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In 1975, when I became Director, I think oneof the most prominent defects to be repaired

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at the boundary between NIH and society wasthe definition of those very boundaries themselves.

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More specifically, we had to find ways againsta barrage of criticism to protect our scientific

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programs from regulatory and service obligations,including excessive health promotion exercises

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that can be constant threats to the objectivityand the maintenance of the sharpest edge on

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our instruments of scientific inquiry.