The following is a medical media production from WR AMC TV. In selecting material for this talk on obstruction of the ureter. I used as a basis for the selection of material a page from a recent publication called Gametes and radiology, which I'm sure you're all familiar with. It is a comprehensive list of rick in differential diagnosis and it is by Maurice um reader and Benjamin Felson with contributions by Elliott's keith Harris, her beauty parks and George B. Greenfield, the first three of these more reader, Ben Felson and lethal virus are no strangers to this podium that I'm standing at right now and I am pleased to have them as good friends over the years. Let us look at the list of uh this gamut which is number 831 in their book and just go down the various causes that can produce an obstruction of the euratom. As you will note, these causes are divided into common and uncommon and they are in alphabetical order, which means I will not necessarily present some of these lesions in the order in which they are here, first of all, in among the common we have a blood clot or inspire stated puss calculus. Congenital eureka row pelvic junction obstruction that is banned vessel or adhesion valve, a vessel cystitis across normal bladder with compression or obstruction of intramural puritan inflammation and a Diemer that is pelvic inflammatory disease, invasion or compression by extrinsic malignancy. That is retro peritoneal lymphoma or sarcoma cost normal of the pancreas, cervix or other pelvic organs. Post operative that is lacouture or Diemer around the urethra pregnancy structure. That is congenital traumatic postoperative radiation therapy, inflammatory tuberculosis. Just oh, massages. You re to re seal vascular compression by normal or abnormal vessel or aneurysm. And among the uncommon causes there are benign eureka raw tuna that is polit papilloma, Mesen, Kimmel, Touma Blatter, diverticular um carcinoma of the Euro to primary or metastatic endometriosis, mega colon, popular necrosis where they stuffed happily pelvic lipo mitosis and finally, retro peritoneal fibrosis or Orman's disease. Now, let us look at many of these lesions and have a little discussion on some of the causes for obstruction and some of the embryology and histology behind these lesions. First of all, among congenital lesions causing obstruction. We have here an interesting lesion called congenital blind ending urata. And you can see on this radiograph that there is two years, there are two. Your it is on the left side with one uh in the pelvic pelvis of the left kidney above the other ending blindly at this point right here and rather shortly A second one is this one which is another congenital blind ending ureter and a 35 year old female with chronic urinary track infection. And we see that the duplication is almost complete with the ureter entering uh ending blindly at this point, very close to the pelvis itself. Now, what are these congenital blind ending your edges, they are a failure in an attempt to reduce application of the kidney. Most of these are white type with one year to blind the other connected with the renal pelvis. Sometimes these inter as single as single Eureka's into the bladder. Therefore to your to your general office is on the same side. Or more frequently they are y in type With the two joining together before they reach the bladder. There can be anywhere from 1-2 cm in length, at which time they may resemble a diverticular with the ureter. Or they may, as in the second case here extend almost the complete way. I call your attention to this appearance of a blind ending because we will see this on several other cases where your hands have been tied off for one cause or another. I know of nothing else that looks like this in the ureter. It looks like it ends there. It has no relation no appearance to a calculus or to a tumor. It is a characteristic feature in itself and we will see several others of a similar type as we go along. So much for her blind ending. Eureka's A second type of congenital anomaly is this case of a retro cable ureter. In a 27 year old male with a history of two or three episodes of the material accompanied by lower abdominal pain And the latest episode having occurred just 24 hours ago. The patient's physical exam was negative. His blood count was normal. His urine showed many mucous threads traces of bacteria, 123 red blood cells and 0 to 1 white blood cells. This 15 minute IVP shows gradual accumulation of contrast material within a moderately hydro necrotic right kidney, a normal appearance on the left side. In a 30 minute film we see further accumulation and now we see filling down to the port where the retro cable urata has occurred. And in the 60 minute film we see further filling of the media in the proximal urata. No filling in the distal. You're in a retrograde study was done on the same patient immediately after the IVP. And we see here a feeling of the lower part of the left right urata with a normal size, normal diameter of this section. And we see the typical deformity of the retro cable. Your edit in the film up above there. In this particular patient's surgery was suggested the patient preferred to defer and at last was uh report we have not seen him come back yet for repair of this condition. Another retro cable urata which is somewhat more atypical. Is this one with an associated incomplete rotation of the left kidney. Here we have a more gradual curve of the ureter as it passes towards the midline and downward with very little obstruction to the euro to has shown on the previous case. As we discussed this, let's look back for just a moment at the more characteristic one and let me read you just a little bit about how these occur. Please play, pay attention to this because this is a favorite urinary track question on the board examinations. According from an article by Mayor and Methods. They state this in 18 93. Hochstedt to first described this interesting anomaly, which is also called post cable or circum cable euratom and pre your rhetoric vena cava. The deformity is not due to an error in migration upward of the kidney or your data, but it results from an abnormality of the vascular system. Embry a logically this condition results from the right posterior cardinal vein failing to undergo atrophy and persisting as the adult vena cava. Normally this vein disappears and the right super cardinal vein persists as the vena cava. Occasionally both cardinal veins may possess the vena cava being doubled with the ureter passing between the two divisions. Unfortunately, there are no symptoms pathetic demonic of retro cable. You're usually the symptoms of those of hydro necrosis. Were superimposed infection of calculus. Heh material, gross or microscopic has been frequently noted and was the presenting symptoms in this case right here. Most patients have reached adulthood before symptoms develop as the onset of hydrogen fibrosis is usually insidious. The pilot graphic finding, which is almost pathetic. No Monica. Retro cable. Eureka is the S shaped curve in the upper ureter with displacement of the urine immediately to all beyond the midline at the level of the 3rd, 4th or fifth lumbar vertebra. So much for retro cable. Your otis. Now another case of urethral obstruction, secondary to a congenital abnormalities, abnormal implantation of the Euro. To with an associated eureka, a seal and a female infant in this case with a double kidney and double your. It is on the left. This ivp film at 45 minutes, shows a defect in the base of the bladder here, which later is shown to be the rigorous seal. It shows a filling of a colossal system here which has the group lily appearance of a double kidney. It shows lateral displacement of the uh this portion of the kidney and it shows nothing in the upper part of the kidney. This retrograde study of this uh same case reveals the reason for all of this here is the rigorous zeal in the bladder, causing the bladder deformity. The ureter in this case being implanted at at abnormally low level, which is not uncommon with congenital yuri to sales the Euro to, to the upper portion of the double kidney being implanted, invariably in the bladder at a lower level than the ureter to the lower portion of the kidney. In an article by Salmoni states that your interest seal is a cystic dilatation of the lower end of the ureter associated with our officials to notice stenosis and prolapse of the cyst into the bladder, the wall of the uterus to reseal consists of two layers, The inner layer is derived from the balloon during oral mucosa. While the outer layer represents the vladimir cosa carried downwards on the surface of the prolapse ng urata. The result of all of this is stasis urethral dilatation and infection in the Euro. To and in the kidney. This still yuri to roll the treasure. Another congenital anomaly uh of the Euro to we have already seen at the previous talk. And again, let me just amplify this by showing you uh a longitudinal uh sonogram of the case that we saw earlier in the talk on pelvic masses. Here is the distal ureter producing this large uh translucent mass at this point right here and at a higher level, producing some of this mass at this point. Right here, here again is the Eureka showing its very large dilated sausage shaped deformity, which was the cause for the uh mass. And uh which resulted from the urethral stenosis at the just above the bladder. In this particular case, you can see the deformed small cystic kidney. This is a multi cystic kidney which has its characteristic findings of a small artery, a small ureter or no urata at all, your eternal of treasure etcetera. We will not go further into that description this morning. Now you readable calculus. I probably the most common form of your federal obstruction of all. And here are a few atypical cases of this condition we have here a small calculus with a very high grade obstruction, resulting in real extra visitation of the contrast media with the IVP. This patient was 68 years old. He was. She was awakened at one a.m. with a sharp left sided flag pain. They close up is shown here of this very small calculus just in the lower your, approximate to the bladder entrance. On this examination. At five minutes we begin to see an accumulation of the contrast material in the involved left side with hydro necrosis of the left kidney, normal findings on the right side. At 15 minutes there, further accumulation of the media. And at 30 minutes we now see the filled system with extra visitation of some of the media media presumably back flowing from the what are these with dissection downward along the kidney pelvis and along the upper part of the your Akhter as well. A very characteristic appearance of extra visitation of media from the kidney and very commonly and not commonly but occasionally seen in high grade obstructions of an acute eureka associated with an acute urinary calculus. The stone eventually was removed with a basket catheter in this individual case. Uh a complication of pregnancy is the presence of a charitable calculus. And here we have such a case. This is a close up of the calculus just adjacent to the infants. Uh, fetuses, head at this point right here and a long shot of the whole system shows the distended your to down to the level of the calculus here. The stitching above here and the hydro nephritis kidney here. The presence of media in the you're too down here probably uh excludes the possibility of the so called ovarian vein syndrome, which is also another. Your it'll type obstruction associated with pregnancy. And we will see such a case of that in just a few minutes. Here's a calculus in a patient who has had an illegal conduit uh, secondary to a pelvic clean out for carcinoma of the cervix, one of the most common malignancies that will produce a frozen pelvis and necessitates uh a diversion of the urinary stream, usually into an illegal can't do it. On the left side, there's normal function and the media is passing into the illegal pouch here. Excuse me. This was not an illegal pouch in this case. This was one of the old fashioned sigmoid pouches which used to be done. But because of various reasons including infection, they are not done to any extent anymore. The right side shows a new program, but no feeling of media and we trace it down to this point right here and we see a calculus in the lower part of this respected urata, just proximity to its entrance into the illegal conduit. This eventually passed and the patient was relieved of the pain. There's a calculus that resembles a tooth. This is merely put in here to say that one has to differentiate occasionally a calculus in the ureter large calculus from a possible tooth within a derm board of the ovary. There are no other findings here to indicate a Dermot of the ovary other than the presence of this large calculus which does resemble a tooth to some extent A far invited within the euro to may produce similar obstructive symptoms. And here is one in a 23 year old female with sickle cell anemia. And we see two foreign materials within the uh you're too here at this point. And at this point, right here in this retrograde study and on a drainage film, made a short time later, we see that there have been impregnation of these non opaque densities in the uh your turn at this point and at this point and we see uh a rather large uh kayla sees in the kidney superior lee here to some extent a little bit lower here. And obviously this is a case of papillary necrosis and a sickle cell er who has stuffed the potbelly. And they have passed down the ureter causing a partial obstruction of the urinary so much for calculator to go now to your Itaru tumors. Let me very quickly give you a classification of the tumors that may be seen in a euratom. And then you show you several examples of these. First of all, there are the epithelial tumors and these may be benign or malignant, The benign being the papilloma as polyps and the adenomas and the malignant epithelial tumors being the transitional cell carcinomas, squamous cell carcinomas and adenocarcinoma. In addition to the epithelial tumors, there is also the occasional meta dermal uh tumors which include among the benign the five Roma's hemangioma is a blood vascular tumors, mama's limb, Fangio mazar lymph vascular tumors and among the malignant there maybe the occasional sarcoma of the urine. You read all chambers have about a 1-2% incidence of all guiyu tumors. They occur in male, about 2 - one over the female. They range anywhere from the teens and 20s up to the later years. The 80s and the 90s. The mean for these lesions being about 74 years The pathologist shows 75-80% being malignant and most of these are of the epithelial origin. The location is usually in the lower third. In about 75% of cases, the symptoms include about 70 to 90% of cases with the material, 20 to 35% with pain associated with the material, 2 to 5% short and abdominal mass. These would have to be very large in such a case And about 10-20% showing abdominal pain alone in this case. Right here we have a benign. Excuse me. In this case. Right here we have a transition. Excuse me, I'll go back again. The first case here is a urine or a polyp in the mail with the material. This retrograde study of the urinary track reveals a filling defect in the lower part of the left ureter with slight dilatation of the aorta, just proximal to the filling defect and violation of the euro area and the area of the filling defect, as shown by the catheter outlining the your laterally here. And if then trickle of contrast. Media, media, media media. Immediately When the euro was opened in this area, operation out popped a small polyp on a pinnacle about one cm in length. Surgical findings are shown on this uh sketch right here, the lesion was removed and the ureter was closed without difficulty. A second case, have you read the polyp is of interest? This 64 year old male was admitted for a vascular work up. The initial IVP examination showed a long filling defect in the right proximal year or two has shown right here. Uh huh. There was a mile hydro necrosis of the right kidney. Several I. V. P. S over the next six weeks continued to show the filling defect and the hydro necrosis. And this is the last of the several examinations that were made. This persistent defect was thought to be on the basis of a benign lesion of some type, but a definite diagnosis could not be made that operation. The urethral polyp was found measuring about six centimeters in length and attached by a very narrow base, just distal to the right you p junction. This unusual configuration of the lesion was probably the result of a soft tissue. A tumour contained within a very firm loom in the ureter with a floor of urine, continuously washing the fixed mass and accorded direction, thus stretching it out in the configuration that we see in this case before leaving benign tumors of the Euro. And let me show you an entity that resembles multiple tumors of the Euro to but it's not in reality these lesions are related to chronic infection. This is a case of Eureka right assist aka involving both your photos with a touch of power light of cystic A. As well. In a 62 year old male with a long history of chronic urinary track infection and renal calculus. We can very nicely see demonstrated here the multiple, small, more or less uniform filling defects within the upper half of the two thirds of the right ureter and similar defects within the upper part of the left ear. To hear A little bit about your to write assist, Aka. The first recorded description of you, you read write a cystic a. Was by our friend Morgue agony in 1761. In a post mortem examination of an old man who had suffered from chronic urinary obstruction, he found in both europe is quote spherical drops unquote of various sizes. Cyst formation is the final stage of the proliferated change in the mucosa, which occurs in the renal pelvis ureter or bladder in response to any longstanding irritation, but usually to a chronic infection, solid bands of epithelium become isolated in the to look appropriate and by meta pleasure develop into secretary glands. Finally, the cyst result from retention of secretions elaborated by these glands. The disease usually occurs in the old age groups and is more common in women. There are no pathetic demonic symptoms or signs, but almost always urinary infection is present often with renal calculus. I slightly material occurs very frequently and is thought to result from spontaneous rupture of one or more of these cysts. The retrograde you're a gram is generally the best method of demonstrating the disease, although a good IVP can do it too. The salient feature is the presence of constant small defects in the contrast field urata or renal pelvis. They may be large indiscreet or multiple and small and may occur anywhere along the track, including the pelvis of the kidney, the Yoda and in the bladder tune differential diagnosis. Although really this can, this looks doesn't look exactly like anything else includes air bubbles, multiple papilloma to tuberculosis, granule ations, multiple small calcula blood clots, and possibly multiple hemangioma. Tous formations within the irritant. So much for benign lesions, let's go now to the primary malignant lesions of the aorta and as I've already mentioned, most of these are of epithelial origin. Here is a rather characteristic, typical pathetic pneumonic picture of a primary transitional cell carcinoma of the ureter and it has rather characteristic findings. First of all, there is what has been described as a goblet or wine shaped deformity of the contrast media column within the ureter. Second, there is a modern dilation of the Euro to just below the tumor, which is rather a constant feature, was first described by Bergman and is known as frequently as Bergman's sign. There is a high grade obstruction here, secondary to the mass of the tumor itself, which occupies a level through here and there is a moderate hydro necrosis and hydro your to approximate to this lesion, the kidney and ureter in this case were removed. A second case of interest somewhat atypical is this patient who was for 65 years of age And had had a four year history of Eureka assisted juncture obstruction. This general was apparently treated prior to admission, but the type of treatment was not stated. Chief complaint was pelvic pain. In this patient, she was admitted. An examination revealed papa limiter on the wall of the bladder and up into the left your them and the lesion was cauterized in the bladder. Three days afterward, the patient was dismissed from the hospital. Three days after the patient was dismissed from the hospital, she had further symptoms pathology and she was readmitted surgery at this time included removal of the left, your removal of the left kidney and removal of the involved parts of the bladder. The pathological diagnosis was superficial transitional cell carcinoma of the bladder with extensive papilloma ketosis of the lower ureter, which probably was a superficial uh involvement of the ureter in a similar uh type of histology that is transitional cell carcinoma in this patient. Right here, the transitional cell carcinoma began in the kidney and was later ceded to the euratom. Here is a patient who has a deformity of the upper pole of the left kidney with an infant nebula involvement and a superior pelvic involvement here. Further study showed that the Euro two was normal in this case the patient was an elderly man with cardiovascular disease. So it was elected to do only an effect to me and to remove that portion of the your took which they could get to through the flank incision. The best treatment of these of course, is to remove not only that you're that you can get to that way, but to make a lower incision and remove the lower part of the ureter as well along with a cuff of the bladder and in order to forestall seeding of the tumor downward and re ah development of additional metastatic or implant lesions. This patient later on came back and now we see the stump of the right ureter which was left with involvement at several levels, including right here with transitional cell carcinoma and up here with transitional cell carcinoma, the entire ureter and a portion of the bladder was removed at this time. Again, I point out the bulbous deformity of the approximately end of the ureter here where it was tied off. Similar to that we saw in the blind ending your to at the earlier part of this talk, This patient came in for the next several years with 10 or more admissions for additional fall durations of tumors developing in the bladder and he eventually died of a cardiovascular death, not of a urinary truck death, pelvic abnormalities causing urinal obstructions, including inflammations causing a Diemer, a stricture at the offices to us in the bladder and prostate and prostatic hypertrophy anomalies of the bladder, such as extra fee displacements by pro laps adjacent lesions and so forth. Let's look at three cases illustrating some of these abnormalities. First, here is a patient with extra fee of the bladder with the characteristic deformity of the pelvis, a lack of a synthesis pubis. As shown here. If this patient was examined clinically, one would have seen prior to surgery that the anterior wall of the bladder was absent or poorly developed and that the Eureka's could be seen entering the bladder on its posterior superior side. This patient was repaired and here is a tantalum mesh over the area of repair at this point right here. This had not prevented the patient, though from having an obstructed right your order at least with a hydro necrosis associated in the right kidney. Here is an interesting patient with bilateral obstructions of the your eaters, Secondary to bladder calculate this was a 24 year old male with persistent diarrhea. The patient's history is of interest and I'll give it to you in just a second on a plane film examination these large opaque calculus I was seen. And at a closer look at these, calculate eye, one can see that they have a poorly defined radio lucent center. These were removed and examined and they were found to have as the night us in the center of these some paraffin and the history uh came out that this patient had on several occasions, uh self instrumented his bladder with rolled up tubes of paraffin and evidently at one time some of these paraffin parts broke off into the bladder, remained there and worthy noticed for these large exorcised, calculate I, which developed at a later time. Mm. Here is the examination of the patient several weeks later, following the removal of these. And we can see that the re Toral obstructions which probably were not secondary to the calcula but rather to infection within the bladder and the Deemer of the offices has now subsided and there is no longer any hydro necrosis. This is another example of a broader deformity causing the hydro necrosis. Here is a patient with a sister seal. This was a 64 year old female with the material, flank pain and temperature 104 F. She was found to have a urinary tract infection. She was also found by clinical examination to have a sister seal. A rector sealed and an epidural seal. A passerby was inserted as a temporary measure. And we can see this car didn't quite drop. But that's all right. We can see that the pastry uh one week following the previous examination has cleared up the hydro necrosis here that the earth has now entered at a higher level into the bladder rather than into the pull down and stretched portions as shown on the previous film. And that there is now relatively little if any hydro necrosis in the kidneys. Uh huh. Several examples of urinary obstruction related to surgery here is a patient with advanced carcinoma of the cervix. The patient has had a pelvic clean out and an illegal conduit, elio conduits, as you're probably aware uh isolated segments of ilium which are closed off at one end and the other end is brought out to the skin for drainage. The non resected parts of the Euro. Tas following surgery for the pelvic clean out or implanted into this illegal loop. The remaining ilium of course, which was not used for the conduit is reinvest opposed indian for a bowel function. It has frequently happens that there are temporary obstructions associated with these probably due to uh edema around the office where the Yorkies are implanted into the illegal conduit. It frequently happens that this partial obstruction clears up later. And we have more or less normal findings in the urinary track either on the left or right side on both sides. Here is a patient that had a persistent obstruction to some extent partial in nature which produced a mild degree of hydro ureter and a moderate degree of hydro necrosis uh bilaterally. Another your obstructed by surgery is this one in a 49 year old female. She had a hysterectomy during which the left ovarian artery was relegated at the pelvic inlet. Following surgery and abnormally small urinary output was noted and an IvP was done on here is shown. We see that the left ureter is blocked off at this point again with a bulb ascending characteristic of a tied off or a respected your toe. And that there is a martyr degree of hydro hydro necrosis. This is a four hour film so that the right kidney normal side has already drained out. This patient was re admitted uh For surgery was was re operated upon and the lacouture was removed from the ureter and urinary tract function was normal. Following thereafter this patient was submitted for surgery and she had a vaginal hysterectomy. Uh It was realized after surgery that the urinary output which was first three or 400 CC. On the next postoperative day diminished to zero an I. V. P. At this time was done. And we see here the obstructed your actors with bilateral hydro necrosis and some extra visitation of contrast material due to this high grade obstruction of an acute nature. Similar to that we saw on the left side caused by the urinary calculus. A little bit later earlier the patient was taken to the operating room. Following this, she was prepped and draped in the dorsal, the thought of my position and after adequate general anesthesia was obtained. Both external called Golda plastic suitcases were located, grasp and cut and removed. There was noted to be almost immediate flow of urine from the foley catheter. Here is an example of the ureter after it had been dis dislocated and uh Retrograde Catheters had been inserted into the Euro two for the drainage. Following the surgery, the construction of the ureter is noted in the left side at that point, right there and the construction of the right ureter was noted in the right side, right here. This could be an alarming thing if it was not discovered. But fortunately in this patient, the lesion was determined. The cause for the obstruction was determined and the patient was dislocated with good results. Mm hmm. Finally, some uh your edible obstructions and displacements secondary to non urinary tract lesions. There are many causes for these but we want to cite just a few of them I mentioned a little earlier that there can be during pregnancy. A syndrome which is known as ovarian vein syndrome, in which characteristically there is a cut off of the ureter at the point right here where the your two passes over the iliac artery and vein and the ovarian vein and there's usually no media distantly in the urinary shown here, this is thought to be due to thickening of the right ovarian vein related to the pregnancy. And since the right ovarian vein drains into the in pierre part of the vena cava, it is commonly a cause, it is occasionally it cause during pregnancy for obstruction on the right side. This entity does not occur on the left side because the left ovarian vein does not enter the inferior vena cave and thus does not obstruct the Euro to. But rather it is into the uh renal vein at the higher level on the left side. Here is an interesting case that I have not seen before in a patient with a right urethral obstruction at about the same level as the ovarian vein syndrome, which was caused by a tortuous iliac artery. In this case we see the deformity of the you order at this point right here. In a uh an oblique view, we see a little bit better filling and know that it is not a tumor within the order itself, but rather appears to be caused by external compression and displacement. And in this bleak view, we see that the causes appears to be posterior to the here are two. An angiogram was done on this patient and they oughta graham where they run off into the iliac arteries. And we see a very interesting tortuous city of the right iliac artery at this point, right here which corresponded identically to the defect that we saw on the medial and posterior aspects of the ureter at that point, right there here is an example of a right law urinal obstruction by large endometrium, a in the pelvic area which is not readily demonstrated in these views. But this rvP made because of the pelvic mass with films in Supan and in upright positions shows a fairly marked obstruction on the right side with hydro necrosis and hydro urata. And in the upright film, a leveling out of the heavier media under the urine contained within the pelvis of and policies of the right kidney and a tortuous city of the kidney itself, your to itself. And this was proven to result from the large endometrium in the pelvic area obstructing the right urata to a high grade here is an example of Crohn's disease. Obstructing the right ureter and causing a deformity of the bladder. Several articles in recent times have indicated and have suggested the use of the IVP in all cases of regional underwriters, particularly with involvement of the distal ilium because of the presence of fistulas tracks and thickening of tissues and abscess formation and so on that might obstruct one or both of the year. It is in this case the right ureter was obstructed and there is a mild hydro Yoda and hydro necrosis on the right and there is a deformity of the bladder with an upward elevation into a testing process at this point right here, here is some contrast media barium which had been given to the patient in a previous small intestinal examination. And here is the picture in the same patient of the small intestine showing the mark, degree of involvement of the distal ilium in this regional enteritis. And I believe that these areas right here are the areas that we saw on the IVP where the media had uh collected and had caused thickening and probably abscess formation in this area. And uh this plus surrounding non visualized tissues caused the deformity of the bladder itself. A similar type can happen. Similar type thing can happen in ovarian and in appendix cell abscesses which cause uh mass formation within the retro peritoneal area and obstruction of the right ureter. Here is a patient similar to the one we saw earlier in which there was a retro peritoneal. Adn apathy again, the curator's are partially deformed and displaced by these nodes in the iliac area and in the para aortic areas. And we see some of the deformities here again in this classical picture caused by the enlarged retro iliac nodes on the left side, particularly to the right side to some extent here and at higher levels. The lateral displacements of the kidneys and the ureter is caused by the large masses of retro peritoneal and apathy notice in this case too that there has been some rotation of the kidneys. And this is not an uncommon finding in this entity. And here is a case of the left Eureka and the kidney markedly displaced upward and immediately by very large retro peritoneal mass, which has a relative radio loose syncing. This mass extends all the way from the kidney, above, down into the pelvic area below, and one can see in here relative radio loosest areas with the lines of water density here, which represented the fibrous tissues within a large lipo sarcoma of the retro peritoneal space. Not an uncommon place to have lipo sarcoma developed and particularly around the urinary structures with subsequent displacement of these structures. And here finally, is a large retro peritoneal hematoma. In a patient with hemophilia. And we see here the large mass of blood accumulated in this retro peritoneal area in this patient with hemophilia with subsequent mark deformity of the ureter, even to displacement across the midline to the right side, and with partial obstruction of the ureter causing this hydra necrosis in the right, in the left kidney. So these are some of the examples of your eternal obstructions that were mentioned in Gamut age 31 from the book. Gametes in radiology, I might say, for those who don't know it, that this is a wonderful book for differential diagnosis and certainly one should be on your shelf in your own office or home. This is my last talk to you today, and I appreciate the opportunity that the doctor made well. And his staff gave me for coming to the F. I. P. And giving these four talks on the subjects of the media steinem, the pelvic masses and the uh your natural obstructions. And thank all of you for your attention, a medical media production from w. R. M. C t. V.