1 Diseases of children [B illegible 31] Proposed plan name – history symptoms & causes [Regar] plan of treatment minutely described Other modes of treatment Miscellaneous remedies N.B. Collect all his remarks on art of practising medicine Contents page Introduction Tumour of the head from difficult parturition 5 Cutting the frenum linguae 5 Congenital hydrocele 5 Management of children – as to Particular appetites – Preventive medicine 5 General nature of the diseases of children 6 General operation of remedies in children Diseases within the month Retention of the meconium 8 Jaundice 11 Acidity, Flatulence, Hiccough etc. 12 mothers milk & cows milk 12 Costiveness & its consequences 12:a Vomiting 12:d Diarrhoea 12:f Prolapsus ani 12:l. Aphthae 13 Eruptions in general 19 Strophilus interlinctus or Red gum 19 Strophilus candidus 21 Crusta Sactea 22 Eruptions of Dentition 24 Eruption resembling the itch 24 Venereal Eruptions 25 Infantile Erysipelas (Rose rash) 27 Sore ears (Intertrigo) 30 Tinea capitis [???phlicus]- [illegible] [illegible] on [illegible] [1821-2] 32 Dentition 34 Cholera Infantum 40 Infantile Remittent 55 Mesenteric Fever 61 Tympanitis 66 Worms 69 Volvulus 86 Nervous Rheumatism Infantile [remedy] 89:a. Convulsions 90 Epilepsy 96 Catalepsy 99 Chorea 100 Ulcerated mouth 103:a. Gangrene of the mouth 104 Parotitis or mumps 112 Tonsillitis or Quinsy 115 Rosalia or Scarlet fever 120 Croup or Bronchitis 132 Laryngitis 139 Epidemic catarrh resembling croup 141 Whooping cough or Pertussis 144 Rickets 158 Scrofula 162 Mesenteric fever Hydrocephalus 164 Chilblains 176 Painful aff. from cold without discoloration 177 Burns 177 The cause either is to be found in [???uctural] [illegible] for the [illegible] This will [illegible] men to trust their lives to unknown men, or to fictitious names in the newspapers, where they would not trust property even to a small amount # Formerly prescription of an experienced physician very often set aside for that of the nurse or a negro woman 1 Diseases of children 1 In this part of our course I direct your attention to the history of man in relation to his habits, diseases, & their remedies in his infant state That this subject has occupied the attention of the learned less than any other branch of the medical profession, is universally acknowledged 2 – It is unnecessary for me to enforce the importance of the subject, by any remarks which might be made concerning the evil to society from a neglect of a part of the practice in which the community is so deeply interested 3 – I need but advert to the evils which must result from the practice of committing the management of the diseases of infants to a class in society which is the lowest in point of intelligence 6* [the opinion of the nurse is sometimes taken in opposition to that of the physician – On this subject the world seems to desert its principles of reasoning on other subjects. If a point of law is to be decided men will not trust to a petty of the court, in preference to that of an experienced If a text of scripture is to be explained, men apply to a learned divine in preference to the mere servant of the church & on the subject of wearing apparel it prefers the opinion of the master to that of the apprentice.] 4 – That this subject has occupied the attention of the learned less than any other branch of our profession is universally acknowledged. (The French & Germans however, have neglected it less than the English; and the American physicians have been in the habit of paying more attention to diseases of children than the Europeans) 8 Great attention has been paid to diseases of children within the last 30 or 40 years It has been most neglected in Europe, but less by the French & Germans than by the English 17 European practice differs from ours – but less so at present than formerly because the constitution of our countrymen are coming to resemble those of Europeans 12 It is also the case that European diseases differ from ours on account Disease, here is [illegible] more violent owing probably to the greater of climate etc. Angina [Trachealis] is much milder with them & requires much milder treatment # vicissitudes of the weather 2 5 - The causes which have excluded physicians from the treatment of [infantile] diseases infants, having ceased to exist the subject is now receiving the attention which its importance demands 6 – These causes may be enumerated in few words – viz. the exclusion of the faculty from the practice of midwifery – from the difficulty of obtaining correct ideas upon the subject from its obscurity – the prejudices of the public on this subject – attributing as they do intuitive skill to nurses and matrons * vid. page [illegible] & perhaps also the indifference of the profession 7 – At the present period, however, the enlightened physician watches the mother during the whole period of gestation, receives the child upon its first introduction to the light, & prescribes for its diseases from infancy to old age 9 – As knowledge however must on this subject, as on every other, be progressive, it follows that this part of the profession having but recently received the attention of physicians, has not attained the perfection of the other branches 10 – American physicians need American treatises on this as on other medical subjectds 13 – European practice, as exhibited in their works, is too slow and mild to meet and overcome the morbid excitement of acute diseases in our climate. [Chronic diseases may be treated They practice no deceit 3 with mild remedies, but acute diseases are made worse by remedies if those remedies are not sufficient to overcome the disease The action of the remedy falls in with the diseased action and aggravates all the symptoms if it is not powerful enough to overcome the diseased action IN such cases disease is to be taken out of the hands of nature. The powerful [enemy] is not to be irritated unless there is a prospect of overcoming him] 14 – The difficulty of acquiring a knowledge of the seat of the diseases of children, on account of their being unable to communicate their sensations by language, has been made an excuse by some physicians for neglecting the subject of infantile diseases We may remark however that the difficulty of attaining a correct knowledge of a subject, cannot be given as a reason why it should not be committed to men of intellect & science 15 – Though children cannot communicate their sensations by language, yet the other symptoms by which we determine the seat of their diseases are more uniform in their appearance & more certain in their indications than those of adults 16 Children are under no restraint from feeling fear, [delicacy] or from false modesty In the infant, the mind does not react upon the stomach & destroy its function When Dr Harris published his essay on the acute diseases of children Sydenham said to him “you are the first man I ever envied and it is my firm belief that your little book will be more useful to mankind than # Adult patients also will often deny the existence of dangerous symptoms; for fear they shall be considered as very sick The subject has not yet been thoroughly investigated. No regular course on it has been [illegible] until quite recently in [illegible] of the European schools. I recollect the embarrassment under which I laboured under at the commencement of my practice Cases frequently occurred which were not described in any of the books [&] I was obliged to acquire all my knowledge on the subject from older physicians or from experience. My students have often expressed to me the satisfaction they experience from an examination of my notes and they have often quieted the anxieties of parents by reading extracts from them # In my embarrassment upon being first called to a sick child though familiar with the treatment of adults & having attended the first schools in the country I found my information & in books as to [illegible] nature or treatment and was obliged to have recourse to the older physicians 29 [Dewers] is popular addressed to mothers, very prolix & not intended for a text book but perhaps able [work] & is the 30 [illegible] # Parents think a young physician will do well enough for a young children and are much more apt to call one in for such patients 4 mind does not react upon the stomach & destroy its function We are at no loss how much to attribute to disease & how much to [illegible] # 17 – Still with all these advantages & notwithstanding the importance of the subject it has been neglected & has received less attention than any other branch 18 – When Dr Harris published his essay on the acute diseases of children Sydenham said to him, you are the first man I ever envied, and it is my firm belief that your little book will be more useful to mankind all I have written” This opinion was not founded upon the merits of the book but upon the fact that the attention of physicians would be drawn to this part of their profession, not the least useful though the most neglected 25 Authors on this subject & their merits 26 Underwood Still the department has received less attention than any other branches of our profession 27 Dr Rush in his works, has many remarks 28 Periodicals contain more or less upon the subject 21 – No courses in any of the schools 19 – Some physicians of the first respectability have acknowledged their ignorance & given up to nurses 20 – I recollect the embarrassment I suffered upon this subject # It is a common complaint 22 Since I have lectured upon this subject, our students at parting have expressed their satisfaction. 23 Young physicians are first called to children because the older ones neglect them # hence its importance to them 24 Parents however seem, as a matter of fact, to prefer a young physician, for a young patient! # 34 – I shall first remark upon a few surgical cases which occur to the young physician soon after the birth of the child [illegible] cutting the frenum. I have never seen a case in which this operation was necessary. It is very common for nurses to insist that children are tongue tied. Dr [Eneas Munser] was called in such circumstances he remonstrated the nurse was instant until finally he drew the back of a knife across the frenum & the child he told [illegible] [illegible] hurting and this with this [result] was relieved to the great satisfaction of the nurse. If there is a false frenum it may be divided.” this [illegible] [frenum] is never so short as to confine the tongue & cutting it is a dangerous operation # They will tell you that this particular appetite is indicated by the natural crying of the child The mother will set herself to recollect some former longing of her own [illegible] 6 Hydrocele Young physicians are often called on to prescribe for congenital hydrocele in young children The complaint is apt to excite alarm but neither troublesome nor dangerous. It is readily distinguished from [illegible] by its transparency, insensibility, & not yielding to pressure. In the course of my practice I have had to operate in but one case in children. Dr [Dewers] recommends pouring considerable quantities of cold water on the part. I myself have frequently cured it by washing the part with cold water in the morning and applying camphorated spts in the course of the day. You [illegible] direct the application of spirt & water, camphorated spirits, [muria??] of ammonia, [opium], spirits of nitre, in short every discutient Or you may direct astringent lotion, as a strong decoction of maple bark, spriaea Fomentosa Geranum, Rhei etc. Case in which I had to operate year old probably neglected 2 or 3 inches long about as large as a small egg. Operate without a cannula - with a lancet & catheter & injecting syringe – water 1/6 or 1/8 port wine – children more irritable - vomiting 5 Tumor on the head 35 Children are sometimes born with a tumour on the head occasioned by difficult labour This may be distinguished from a tumor caused by a deficiency in the bones of the cranium, by a uniform hardness. “We may apply mur. amm. or spt & water” 36 – Cutting the Frenum 37. Hydrocele 31 Management Appetites 32 A prejudice prevails in some classes of society with respect to a point in the management of children Some children are thought to be born with a strong appetite for some particular kind of food, which was possessed by the mother previous to the birth of the child & inherited from her. It is thought that the child will [pine] & ultimately die, if this [illegible] appetite be not gratified # It is probable that a belief in this doctrine has caused many children to be killed by the administration of improper food A fact of this kind occurred in Humphreysville, which nearly proved fatal to the child. Vide next page Preventive medicine 33 As a general rule medicine is not to be given to children in health for fear they should be sick. Some are nursed to death, while some die for want of nursing. Some are fed to death while others are starved Some are physicked to death while others die for want of medication injection immediately with [draw] healed [illegible] with swelling The child cried much # - a council of females was called who set themselves to make out what the child needed Finally the mince pie was concluded to be the article the child sucked down the inside & the report was that this effected a cure & saved the life of the infant. Prof. I inquired of the attending physician who informed him that the child was indeed alive and well at present but that it was made very 8ll by the mince pie & came near losing its life. The crying of the child in this case was probably nothing more than a trifling increase of the ordinary crying of very young infants, which is a natural and wholesome exercise # The al. can is large in proportion to the [illegible] of the whole system # The above is a good example of the various prejudices which have prevailed among [nurses] respecting the management of children. Owing to the influence of enlightened physicians these are no disappearing. (examples to be given) 6 38 – Diseases requiring medical treatment General considerations 39 – In investigating the causes and seat of the diseases in infants the mucous membranes claim particular attention 40 The action of this membrane is greater in the infant than in the adult constitution Its secretions are often morbidly increased & are sometimes diminished. It is subject to spasmodic action and to inflammation [illegible] with [illegible] or decomposed with effusion of coagulable lymph. “It is subject to turpidity & to spasmodic action which by sympathy extend to the whole system 41 The liver is much larger in proportion to the body the infants than in adults “& its secretions are much of [illegible] as to quality & quantity than in adults” 42 The secretions are much concerned in their diseases. They are changed as to quantity and quality # Prescott child no ducts lived 3 or 4 months and was excessively emaciated – there was no bile in the stools There was no [previous] duct for the gall bladder into the disorder # There is greater susceptibility to action & tendency to conversion # Just as emetics are given to a stomach [complaint] from excessive quantity of food 7 42 The nervous system of infants is more easily excited, and more affected by the various causes of irritation such as dentition worms acrid substances in the first primae via passages etc. 43 – The blood vessels are more rarely the seat o f disease in infants than in adults – particularly, primarily so much as irritative [acid] if they were affected the action is not [illegible] 44 – Consequently their fevers are fevers of irritation, rarely enteric or those of inflammation 45 Operation of medicines Children bear evacuation better than adults witness the long continued diarrhoea without much debility following, or the salivation for mouths during dentition without a waste of vital energy In operating upon the abdominal viscera it should be [illegible] it is not for the purpose of mere evacuation, it is to produce an excitement for the purpose of overcoming a morbid excitement also to produce healthy excitement a case of torpor # The milder purgatives should be used, the drastic being irritative. Emetics Bleeding Do not bear narcotics vide p. 11 2 – In general the evacuation of the meconium should be effected by the [colostrium] or first milk of the mother which has a laxative property # The child should be put to the breast within 2 or 3 hours from birth # unless [illegible] Instead of suffering the nurse to feed the child for the first 2 or 3 days the breast should soon be presented for if the child feeds it is in danger of losing the instinct to suck If the [colostrium] does not bring away the meconium we may begin with soda as mentioned below or with cold sweetened water Some give a little cold water at first vide [infra] 5 – In strong children cold bathing may be employed with advantage, but the bath should be made tepid for weak ones & gradually used colder as the child can bear it # “If from the exhaustion of parturition the mother be unable to suckle let the nurse commence feeding at the end of 3 hours” vide infra Give a grain of carborate of soda in a teaspoonful of water until iii qts [have] given # The meconium is frequently evacuated during parturition. After birth also the al. canal is set in notion by the crying and mother of the child and the stimulus of the air upon it vide p. 10 skin. # Colostrium is of a yellowish colour probably contains bile & is cathartic # It was formerly supposed that the child should not suck at first. The consequence often was that the child lost the interest to suck 8 Retention of Meconium 1 – The first diseases of infants which claim the attention of the physician are those which arise from retention of the meconium. The meconium is a matter always existing in the bowels at birth & having a dark green colour when evacuated. It resembles tea but is more mucilaginous # It will ordinarily be sufficient to give a little molasses and water to the child until it receives the [illegible] or first milk from the mother which has a laxative quality 6 – If it is suffered to remain a train of diseases may follow. In the diseases which occur within the first moth after birth the retention of the meconium is always to be suspected as the cause 7 – The diseases caused by retention of the meconium are Severe paroxysms of pain in the bowels indicated by crying & writhing – Tumefaction of the bowels. Convulsions. Epileptic fits. Trismus nascertium or Locked Jaw This last disease is very common in some of the West Indian islands, but I have never seen it in this place 8 – Whatever disease may arise from retention of the meconium the principal indication will be to remove the irritation by evacuating the bowels. This is effected by cathartics. A teaspoonful of castor oil is generally sufficient. If [illegible] necessary 1st indic to remove meconium 2nd obviate effects # IT will be sufficient to pour on boiling water instead of boiling the materials in the water The strength however is of little consequence Sometimes the most powerful remedies are to be used beginning with mild. These used full doses of calomel, scammony 2 to 4 yrs – [illegible] assisted by injection, & warm bath until the bowels were moved Wait how long for the operation of each? # By emollient injection, irritation is allayed, and if the lower part of the bowels is excited the rest will be Dose 2 to 6 pills each pill containing 1 gr. of (calomel) # Chalk & calomel is a substitute for blue pill – perhaps the chalk qualifies the cal & at least it corrects acidity Antimony should scarcely ever given to children within the mouth # A great part of the calomel has no effect [illegible] it does not come in contact with the coats covered with mucus In cases where there was great quantities of [mucus] I have given full doses of cal. 9 the dose may be repeated every 4th or 5 hours until half an ounce has been given 8 – If the oil is rejected from the stomach Senna & Manna may be given – zi of the former to zss of the latter boiled in gill of water # & administered freely until the bowels are moved once in ¼ or ½ hour “ Rx Sennae zi [illegible] ferv. 1 gill 1 or 2 teaspf every ½ hour” 9 – The operation of the cathartic should be assisted by emollient injection # 10 – Fomentations to the bowels will assist the operation of cathartics & if spasms exist, will always be needed for their relief 11 Cathartics of various kinds 12 The best cathartic which I have used for infants within the first month after birth is the blue pill (or [mellated] pill It rarely offends the stomach and never produces griping By it the action of the liver & the secretions from the mucous membrane of the intestines are excited more than by any other cathartic except perhaps calomel. In my practice I have never known an infant salivated by it. # 13 In severe cases where the blue pill is insufficient we must have recourse to calomel, which may be given in doses of from two to 10 grains. It is often necessary to give as large doses of calomel to children as to adults owing to the great quantity of mucus in the intestines by which they are defended from its action. # The meconium scammony or jalap as a laxative & had them operate mildly If the cots were [naked] [illegible] a dose would prove fatal for irritation # This is a mild cathartic and supposed to act chemically. # “Evaporate the [illegible] over the fire stirring it until thick then add chalk till it is of a consistence suitable for pilling Each pill may contain 1 or 2 gr. of Dose from 2 to 5 gr. Or it may be dissolved in herb Fish, gall has been recommended [illegible] gall Rattlesnake has been thought to have specific properties especially in fevers. This article is bitter, tonic [illegible], laxative, & [illegible] Continued from page 8 “The infant may be put to the breast in one or tow hours from birth This course will produce permanent contraction of the [uterus] & tend to stop [hemorrhage] & prevent milk fever” When an infant is first born it is well to wet its mouth with half a teaspoonful of coldwater and give it nothing else until it is applied to the breat 10 while retained will likewise prevent the operation of the remedy by involving it in its viscid substance 14 Chalk & calomel may be used in doses of 1 gr. cal. to 4 or 5 chalk repeated once in 2 or 3 hours 15 Other cathartics which may be used are or as recommended by Dewers 1 gr. carb. sod. to a teaspoonful of water repeated every “it operates” 15 minutes until 10 gr have been given. # Decoction of the flowers of the dandelion & the mullein Senna 2 dr. to with 4 dr. of aromatic herbs or seeds The bile of animals (ox gall) is a good cathartic Perhaps we may consider it as acting as a substitute for the childs own bile. It may be given in [catnap] tea milk etc. # 16 An injection of bitter or 16 aromatic herbs will allways assist the operation of whatever cathartic you use & in mild cases frequently will be sufficient of themselves – superceding the necessity of giving anything by the mouth Continued from p. 8 The stimulus of sound upon the child, crying, irritation of the air upon the skin, and especially muscular motion, excites the peristaltic motion of the child. The influence of muscular motion upon the peristaltic action of the bowels, is considerable, as is seen in horses while travelling, the costiveness of sedentary persons etc. “The warm bath at the temperature of 98 or 100 assists the operation of cathartics renders their action more mild equalises the action of the system and nervous irritation It is especially useful when convulsions are present and may be used at any period except in cases of extreme exhaustion” # It is the most powerful antispasmodic for children [have] acting upon the extremities of so many nerves Jaundice “Jaundice sometimes appears at birth indicated by the yellow colour of the countenance and arising from obstruction of the liver etc. Such cases are generally incurable. The first remedies are the mild deobstructant plant, small doses of calomel etc.” 11 When convulsions are present the warm bath should be used to assist the operation of whatever cathartic is used, to render the operation mor mild, to equalise excitement and to remove irritation. This remedy may be safely used at any period after birth # After the cause which excited the convulsions has been removed, if the morbid irritation of the nerves continues, the bath will again be serviceable 18 Antispasmodics may likewise be used such as valerian, aqua ammoniae, elix. asth. artificial musk infusions of catnip etc. We may use aqua amm. 3 or 4 drops or carb. amm 3 or 4 gr. or asafoetida a teaspoonful of the tinct. in milk & water, or camphor by enema Be [cautious] of giving narcotics to children Some are more susceptible than others. And some children are accustomed to [them] from birth. Case of a mother who had inured a child of 3 m. to bear 30 dr. of SS. I proposed to give paregoric, beginning with 8 or 10 drops, and found that the child had often taken with impunity 31 dr. of SS. to produce sleep 4 – “Child bed women are generally to be treated with mild diet for the first week after delivery, unless their strength has been much reduced by parturition, when they may take port wine in moderate doses” # “If light stools indicate a deficiency of bile the administration of oxgall will be found very serviceable vide [illegible] If acidity is produced, add limewater, If diarrhoea is produced, use arrow root instead of the water, or any other [fecula] Children are apt to receive too much food; hence cow’s milk should be diluted with water. Milk may sometimes coagulate in the stomach of children, in large quantities and occasion much uneasiness Meat should not be given under 6 mo. unless in particular cases which are exceptions to the general rule, where milk disagrees or perhaps in the case of some scrofulous children 12 Acidity Flatulence Hiccough 1 – Very young children are often troubled with acidity, flatulence & hiccough These affections may be removed by a free use of magnesia, lime water, or aqua ammoniae 2 – It will not always be sufficient safe? to administer these articles to the child alone. The mother or nurse must often take them likewise 3 – Sometimes the mothers milk disagrees with the child. This will be known by the constant disorder of the bowels of the child. by the evacuation and pain suffering after nursing both child and [illegible] mother may seem to suffer without a cause The stools may be slimy# The child may cry obstinately 5 – If the mother’s milk continues to disagree we may use cow’s milk diluted with one third or one half water & “sweetened” or with arrow root mixed first with a table spoonful of cold & then with one of hot water, in order to make a homogeneous mixture 6 – Children fed on cow’s milk are more apt to be costive. To prevent this give a little magnesia, decoct. of dandelion etc. Peach tree blossoms are much used, but are too violent in their operation The injection will start the machine again The injection may be made of Eupatorium, catnep, elderflowers mallows etc. etc. Apply first whatever can be first prepared counterirritants for instance. Spirit or mustard to the fat ammonia etc. ammonia to the mouth and nostrils etc. endeavouring to rouse the patient 4 – [A young physician should be careful to know what to do in sudden cases (much depends on a favorable impression at first) Neighbors and friends usually assemble around a child and the expect the physician will be able to prescribe at the moment. In such cases set some of the bystanders to preparing a warm or tepid bath – no matter if eventually if it should not be used. Set others to preparing some other thing and so on. Thus while the attendants are all employed he will be able to devise some course to pursue] I recollect an old physician in this situation who was pressed what to do & replied “stop let us think about it” 12:a. Costiveness & its consequences 1 – Physicians are frequently called upon to prescribe for infants who are in health except that they are costive Children fed from a spoon or bottle are mor to be thus affected than those who are nourished from the breast. If costiveness is produced by improper quantity or quality of the food as is sometimes the case, the diet must be changed 2 – Costiveness if not attended to in time produces flatulence, watchfulness, startings, hiccough, diarrhoea vomiting & convulsions 3 – A physician is frequently called to children I fits, who have been apparently well until the convulsions come on The safest and most efficacious prescription that can be made, is an injection & indeed is all the treatment that most cases will require. Let a warm bath be immediately prepared & the patient put in it if the enema does not relieve. While the convulsions continue the mouth is closed & we can operate on the system mainly by the rectum & the skin 5 Be careful to make your directions for administering an enema very definite, unless you know that the family are familiar with injections Case of a mason’s man hands & knees shooting somewhat off fright rolling over murder The enema may consist of simple warm water, or milk & water, or of tea of thoroughwort or catnep etc. a table spoonful of salt may be added finally castor or other oils may be thrown up in extreme cases the rectum has been filled with lard The water for the tepid 12:b. bath should be about blood warm. Be careful to bathe the child, & not merely to scatter or sprinkle water on it. The length of time during which the child may be kept in the bath may be from 5 to 20 min. While the patient is in the bath if it is sufficiently relieved to be capable of swallowing give a dose of calomel for a child of 6 months 6, 8 or even 10 gr. If improper food is the cause 20 gr. are not dangerous, for infants will bear full doses of cathartics though very small ones of narcotics In bad cases of convulsions the means to which we have it in our power to resort, are external irritants such as garlic draughts to the feet, injections of [nervines] the most powerful of which will be a teaspoonful of tinct. camphor thrown up in a gill of milk & water & the warm bath until we can administer articles by the mouth “If the child be feeble & exhausted upon coming out of the bath give cordials or tonics” Any quantity of food in the stomach & bowels which is not congenial, interrupts the process of digestion & the peristaltic motion functions whose importance is second on ly to that of respiration. When these functions are interrupted the muscles are brought into convulsive action to relieve the system Be particular in your enquiries about food for those who have the care of children are very careless and children will swallow whatever is put into the mouth. I recollect being called to see a very strange worm which a child had voided. The imagination of the attending physician & parent were excited. To me whose imagination was cooler the worm appeared to be a piece of bark I enquired if the child had had no slippery elm bark & found that it had been chewing some. Then the supposed worm was accounted for Rye flour is more apt to become acid than oatmeal # Cal. sometimes by its irritation produces convulsions I have known a family, all the children of which were thrown into convulsion by cal. & I was obliged to be very cautious & use blue pill injections etc. There are several milk remedies such as dandelion which is tonic laxative, & deobstrument acting on the liver, mullein fl. elder [blo??] tea “The pollens of most plants has a laxative quality” I have seen no danger from the prussic acid of the [illegible] flower & it is much used [illegible] from [illegible] also among the French they hold a place the French Pharm. Wild liquorice [gal??] [Circa???] resemble the dandelion Moderate friction excites the bowels Sometimes alkalie or chalk, though generally they are rather constipating, prove laxative probably on account of the acid combining 12:c. II II Where is a tendency to costiveness, the use of oatmeal gruel or porridge will be beneficial or a porridge made of wheat flour with the bran, strained through a cloth & mixed with the milk with which the child is fed also rye meal gruel or rye bran gruel If the health is not affected by the constipation be cautious about giving much medicine. It is always better to cure this affection by food than by medicine. # Castor oil from a teaspoonful to a table spoonful is the best cathartic magnesia given with the milk is a good remedy but not always sufficient. Elixir salutis is one of the most common family medicines. This article with castile soap dissolved in it has been found very serviceable. The gall of animals may be recommended. The blue pill operates gently as a cathartic & is useful in changing the habitual disposition to costiveness. I have prescribed with advantage decoction of the flowers of the dandelion, or mullein. The flowers of the peach tree are much used for the same purpose but “are rather too powerful for ordinary cases” “They are powerful even for adults” & sometimes gripe unless combined with aromatics Calomel may be used with safety # “In severe cases mustard and ginger may be applied to the abdomen” Mechanical manes in the form of suppositories are much used by nurses such as a piece of molasses candy or a roll of paper moistened with oil. They are beneficial. # If the child has been weaned pay particular attention to its food. Nurses are very careless. # “No serious evil will arise unless young & anxious mothers should give medicines and thus make the child sick” “If vomiting arises from dentition we must remove the irritation Give laxatives, as magnesia, & narcotic Children should be early accustomed to the reception of enemata to prevent subsequent prejudices upon the subject. I recollect the case of a child about 12 who was suffering from an obstinate constipation caused by an affection of the lower spinal nerves which produced a partial paralysis of the rectum and bladder so that a catheter had to be introduced & injections were [illegible] demanded. But all the efforts of the nurses (women) were unable to administer an enema Calomel had been given until the mouth was affected, yet without producing an evacuation. Finally the patient went into an insensible state, and injections were given & produced free evacuation. I have heard adults say they would die before submitting to receive an enema. 12:d. Vomiting Spontaneous vomiting in infants arises from over distention of the stomach. The discharge is made without nausea & almost without effort, & consists of pure milk or milk coagulated. The mother should simply be cautioned not to allow the child to nurse so long at a time. # Children and old people vomit with more facility than the middle aged If vomiting arises from the sympathy of the stomach with some other part of the system which is in a morbid state, the primary disease must be first cured & used for the irr. of stom. For the vomiting itself in palliative we may prescribe lime water & milk. a teaspoonful of each; soda water, or any liquid affording an abundance of carbonic acid. Vomiting from irritability of the stomach or free [illegible] requires particular attention. The attendant symptoms will be paleness of the countenance, quick & feeble pulse, & cold extremities. Irritants must be applied over the region of the stomach. They may consist of ginger, mustard, horseradish leaves, mint etc. aqu. amm. [illegible] essent oil dissolved in alcohol” The alkalies such as pearl ash, also soda water “lime water” may be given internally. Excite a discharge from the bowels by injection or a calomel cathartic to remedy the irritated action of the stomach “[illegible] counterirritation” The warm bath will be very serviceable, soothing the nerves of the skin & by sympathy producing the same effect upon those of the stomach nervines also may be given We may try putting a little brandy into the mouth or a small quantity of capsicum tea. Hot cloths & fomentations may also be applied externally. A large bulk of warm water water may be thrown up the rectum in obstinate cases, use stimulating injections.. One of the most convenient modes of administering a large injection is by a pipe fastened to a large ox bladder Press the fingers against the end of the pipe which the bladder is fastened so as to make a valve and prevent the escape of the fluid contained in the bladder, until after the pipe has been completely introduced into the rectum # I used to carry this recipe about me when I practiced in the country Frequently irr. of stom. is overcome by irr. o f the rectum by an enema of salt & water or by a large injection to produce a peristaltic motion downwards 12:e. Ren “Remove the cause, which is frequently indigestion. If it proceeds from the teeth, lance the gums The following is an excellent recipe # in these cases Rx Cret. ppt zii sem. card. zi bi carb. potas. zfs grind aqua bullientis 0 fs Give a tablespoonful every half hour I am inclined to the opinion that the alkalis, such as pearlast act by creating an excitability Emetics are particularly safe for children much more so than for adults. Ipecac is generally the best unless the disease in which the emetic is indicated is very threatening, when antimony should be used Squills are indicated in emetic doses in complaints of the chest “with [illegible] [illegible] but should not be administered when there is much inflammatory action in the system. “Warwick’s powder a preparation of antimony, was once popular and often administered without the advice of a physician. I have known it endanger life Nurses should never prescribe antimony” Some situations are more liable – low situations [seashore] Children shut up in low dark apartments suffer from want of amusement. If a diarrhoea from teething is suddenly stopped the brain is apt to be affected. This affection of the brain is peculiarly liable to occur in children. There is no outlet to the brain 12:f. Diarrhoea This complaint sometimes affects children for months & even years Some families are more subject to it than others & I have known those in which all the children would be affected with diarrhoea from a period soon after birth until they were three or foru years old. The children who have this predisposition to the disease are born with diseased liver and bowels & have indeed all the chylopoietic viscera in a disordered condition. Hence among the causes of diarrhoea we may rank a bad constitution. Other causes are want of cleanliness, bad food “want of sufficient clothing” bad air damp rooms, confinement & want of exercise. Exposure to cold & moisture A bad air probably causes diarrhoea mainly by its depressing influence. The effect of confinement and want of exercise is very great. Young animals suffer in the same way Even vegetables seem to need motion for I think I have observed a great deficiency of fruit & a sickly appearance of fruit trees after a season uncommonly free from wind. Confinement is injurious in another manner Children need mental stimulus from a variety of external objects. I have known surprising cures effected apparently by the operation of this very principle. Teething is a frequent cause & whenever it is we must palliate & check, but may not stop the diarrhoea From the sudden stoppage of a diarrhoea during dentition you may expect an affection of the brain to follow. The discharge from the bowels in this case is similar to that of tears from an irritated This will be convenient in many cases as in travelling Other mints may be used spearmint is most agreeable I have given this in the latter stages of the diarrhoea of adults with advantage Almost any cath. will often check a diarrh. Cal or blue pill is generally best Judgment is to be exercised whether to prescribe an emetic or a cathartic & as to the choice of a catheter Ipecac however is almost always safe children bear emetics well Put the parents & the nurse upon investigating as to [diet] Persons are apt to very careless about giving things to children And they may have wrong notions as to particular articles Prohibit solid oily food, crude vegetables and esculent roots. Potatoes are very bad in diarrhoea so are the analogous roots. They contain indeed much fecula, but also much 12:g. eye, or of mucus from the lungs The expressed juice of mentha vulgaris, boiled skimmed and mixed with white sugar is an agreeable, & useful article for the cure of a diarrhoea, which has continued but a short time & is not severe. In the early stages of a diarrhoea, which is sufficiently severe to demand the attention of a physician it will generally be best to commence the treatment with a cathartic; though if fever accompanies it an emetic of ipecacuanha should be the first article administered. Judgement must be exercised in the choice of a cathartic. Calomel will be best if the child be not particularly feeble or of a very delicate constitution & for a feeble child the blue poll. I myself was for formerly many years unable to take any other cathartic than the blue pill without being griped. Generally it will be best to combine chalk with the calomel, as the latter is indicated for its deobstruent, rather than for its purgative effect. The dose may be about 2 gr. cal. with 5 or 6 of chalk If improper diet is the cause the food must be changed; & it will generally be necessary to be particular in our enquiries with regard to the diet for the parents may consider many things a safe which would be strictly forbidden by the physician. Especially will it be necessary to attend to the diet if the child feeds instead of sucking. Every thing hard of digestion, such as salted & oil food should be prohibited The diet should be arrow root and in case of diarrhoea this article will be improved if prepared with a little laudanum or wine sago taipica, which is probably a hydrate of besides They are apt to become acids & acrid in the bowels. In the Polyn. islands The inhabitants living upon taro are very liable to diarrh. West of the Rocky Mts Lewis & Clark found the inhab. subject to diarrhoea for living on a root [illegible] [illegible] men suffered in the same way after they arrived among them In the evacuations & the evacuations of children shd always be exam [may] [illegible] that potatoes remain undigested Cullen & Rush thought different of potatoes The evac. of chil. should always be [illegible] Pies cakes articles containing much sugar hot bread should be prohibited Bread shd be toasted The juice of meat will often be beneficial No gravy (i.e. artificial or carbonized fat with flour etc.) Potatoe starch, pure, is perhaps not inferior to the tapioca etc. Boiled flour becomes s hard as stone almost hydrate It is an old practice It is an excellent preparation make a porrige of it grated Tapioca I suppose is made by sprinkling casserva root, powdered, with water & baking it making a preparation what appears like gum arabic. I have not been able to learn how it is made, but have made it this way a similar substance of arrow root Arrow root & the tapioca are cooked by first dissolving them with a small quantity of cold water & then adding hot water. In this way [illegible] are avoided 12:h. flour or roasted or baked flour made into a porridge with equal parts of milk and lime water. The bread should be toasted and butter should be used very sparingly gravy not at all. Casserva sago etc. An article similar to tapioca, if not the same may be made in the following manner. Tie up a quantity of wheat flour tightly in a clean cloth & boil it for 5 or 6 hours The result will be a hard substance which is to be grated & “[illegible] milk & water or with lime water” made into a porridge this will be palatable & good Rice in gruel, or thoroughly cooked by boiling The worst cases of diarrhoea are attended with feeble pulse, cold extremities, dry skin, & generally a rise of fever once or twice in the 24 hours. Soften the skin by the tepid bath which is [illegible] etc. and keep up an action on it by flannel unless there is fever & in such cases use also absorbents freely with tonics & aromatics. The chalk julep or white decoction will be as good a preparation as any. Rx Chalk [illegible] zfs to zi pul. cinnam. to zii zii, bum arab zi carb. potas. zi water lb I. boil ½ hour Sometimes [illegible] a similar recipe shd be used” The Europeans add [illegible] use [illegible]” a little laudanum may be added. Of this feed freely, giving say a table spoonful from ½ tab sp. to I once in an hour sometimes. As a tonic the vitriolic or tonic solution of Moseley is inferior to none in such cases Rx zinci sulph ziii alum zi water lbi Give from four to twenty drops. Tonics must sometimes be combined with absorbents Opium is always safe in cases where the bowels have been thoroughly evacuated. It is generally better to combine it with ipecac, which will determine its action to the skin and act as a gentle tonic & laxative The tepid bath is [illegible] as it may be called) relieves the irritation of the bowels through the skin Chalk does not act mechanically or chemically it has a specific action upon the stomach as much as bark Make white decoction in various ways if cinnamon offends use some other spice Sometimes add astringents or [illegible] Tonic sol. sulph [illegible] ziii al. zi Mosely sometimes used al. zii In 3 or 4 gtt it is anti emetic In larger doses it may be emetic & cathartic This is a state of the system similar to the collapse of cholera Asiatica It is a collapse taking place during diarrhoea. I have found advantage from stimulating or acrid injections as salt & water, mustard In chronic diarrhoea opium is often invaluable. Some families are obliged to give it 2 or 3 times a day for along time to their children until they are so old as not to be liable to continual diarrhoea The stools may be green clayey from deficiency of bile sour curdled [illegible] or very fetid, so much so as to be very offensive turning the stomach of the attendants. 12:i. In cases of chronic diarrhoea where there is attending it much sensibility and irritability of the bowels opium combined with diaphoretics cathartics or tonics is an invaluable remedy Sometimes violent symptoms supervene vomiting supervenes & the diarrhoea stops the patients hands & feet grow cold his pulse grows small, & if the most active measures are not take used the patient dies in 24 hours. When this change of symptoms take place we must resort to the most powerful means of exciting counterirritation such as application to the epigastrium of mustard, horse radish leaves ol. monardae punctulae, ol. turpent. etc. Such articles as pimento will be grateful and stimulating given internally We may give calomel, opium & the carbon. acid, and use stimulating injections. “Effervescing mixture with SS. [illegible] appt” Particular attention should be paid to the kind of They may be sour & curdled, or mucousy, [illegible] clay colored, water stools for much may be learned from their inspection. Acid is often formed in the whole alimentary canal, producing sour and curdled stools which will indicate lime water or other absorbents, with aromatics. The acid may arise from fermentation or more probably from secretion Such cases I have often cured by the expressed juice of the spear mint prepared as above mentioned & given freely. When the stools are green white, or clayey, give opium to allay irritation. Ipecac to equalise excitement, & the blue pill as a deobstruent, the latter in small doses so as to move the bowels, but once or twice in the 24 hours. Alkalis are useful as # Noel’s plaister was made of white lead red lead castile soap and olive oil, boiled till the red lead was so far decomposed by the oil that the mixture was of a cream colour It is a smooth plaister and is less stimulating than [illegible] Use soft charcoal by burning cork, which is the popular kind or cedar Dose teaspoonful to a tablespoonful in a convenient liquid Lime water & other alkalies may always be given They may be mixed with the food without [injurious] the taste When the disease has continued long & patient is [illegible] phlegmatic temperament we may bandage the bowels, to give mechanical support [Opium] also will be useful applied externally in this way Adults from the Wt. I. with chronic diarrhoea will look like a mummy Bog water is a very soft water & contains carb. hyd. Astringents [illegible] tinct. vitriol decoct. of oak bark with milk & sugar & spice Bandaging & plaisters Take any adhesive plaster and mix about ½ opium Or soap and opium Acetate of lead is not a new remedy 1 2 or 3 gr a day 1 gr at a time continued as long as the relaxed state of the bowels continues as long as they last lead [cholic] cannot take place for 12:j. are also enemata formed by dissolving castile soap in mallows or catnip tea. If there is much griping with tumefaction of the bowels injections of camomile tea give great relief. In diarrhoea of this kind the following is also a good stimulating & correcting laxative Rx castile soap zi elix. sal. zi dissolve & give it 3 or 4 times a day of teaspoonful or ½ teaspoonful doses. If the stools are fetid give charcoal internally. It will correct the fetor & it sometimes cures the disease. For sour stools vie last paragraph of this lecture During the long continuance of chronic diarrhoea it will of ten be advisable to apply mechanical support to the abdomen. We may apply a plaister of white diachylon [illegible] plaister alone or with opium or of lead and soap & a bandage. In chronic diarrhoea the skin becomes brown, of a dark & dirty appearance, & very dry and husky If the tepid bath does not relieve this symptom, we may apply water from peat swamps, which contains carburetted hydrogen. Vide Duncan’s commentaries In the last stages of diarrhoea we must resort to tonic solution to astringents, absorbents & aromatics we may also use opium with cathartics, emetics & absorbents & If we met with a great craving for salt food it should be gratified. The gratification of such an appetite will prove a stimulus, especially to the mind & consequently the more powerful. We meet with similar cases among adults also. Case of a man who could retain no medicines upon his stomach & finally recovered upon bread & cheese, given at his request In the latter stages also of chronic diarrhoea, acetate of lead the [illegible] [become] very lax and there is generally a prolapsus ani patient being [semiphlegmatic] I saw this article much used in this way when a young man and though expecting bad colic no injury resulted. Prof. Smith was very fond of chocolate [illegible] It sometimes acts like a charm Spiraea may be given in decoction or extract. [illegible][illegible] is not so good being unpleasant having a fishy taste & offending the stomach Ger. mac. & [illegible] [arom.] are pure astringents & unobjectionable on this score. I have prescribed sometimes one, or another, according to convenience of locality where I happened to be The root of typh. latif. is used as food by the aborigines European physicians give [althea] [illegible] which is the true marshmallows Usually when diarrhoea has continued long the kidneys become affected. Mucilage will then prove diuretic probably by their [illegible] affect. The terebinthinates will then be useful. The most common practice in this neighborhood is a decoction of white pine bark especially with a little milk it is called healing to the bowels. There is also nutriment in it for the aborigines, sometimes live on it When mucilages to wear out we may resort to terebinth. The species of [polygnomic] knot grass are 12:k. may be given internally. There will be no danger of the production of colic, by this remedy, for the bowels are too much relaxed. The astringents just mentioned may be various We have at least fifty indigenous vegetables, which may be used given in decoction of milk or water such as the bark of the currant, the raspberry, the various species of oak, of viburnum chocolate of acorns etc. white pine bark in milk etc. the roots of the [illegible] of the [geranium] etc. The viburnum Especially deserving of recommendation are the spiraea tomentosa & cornus circinata. The latter of which equalises excitement Of mucilages we may have occasion to use a variety for irritation for any one article may become worn out & another be more grateful We have typha latifolia, twigs of sassafras, hibiscus, malva bran, flax seed, slippery elm, gum arabic etc. all the mallows, all the [illegible] marshmallows hibiscus palustris called rose of [illegible] in the gardens root is [illegible] [illegible] & sub astringent Sour stools Be particular in forbidding the use of animal food. If there be want of bile, give ox gall, lactescent plants dandelion etc. with mild mercurials; e.g. calomel 2 gr. with 6 gr. chalk. Aromatics also may be combined. Astringents elg. [illegible] speraea cornus & geranium do well. Also the following Rx calc. magn. zfs rhei palm. gr. 8 acaciae zi ol. anisi gtt vi aquae purae zi Give a teaspoonful at a dose. “once in 2 hours” In bowel complaints with griping attended with green or sour stools Rx magn. ust zfs pulv. rhei grs viii pulv. gum ar. zi ess. menth pip. gtts vi water zi dose, teaspoonful Spiraea & cornus used – they are mucilaginous sub astringent & diuretic Articles of a stimulating kind are often needed in the latter stages especially erigeron canadande (colt tail) [illegible] The bitter [illegible] which grows in similar situations (ambrosia [elatio??] is also used as a bitter apparently nervine in diarrhoea Roman wormwood) [Cupron] is acrid, sub astringent & diuretic much used in the middle states improper when there is entonic action case of cholerine cured last summer by this garden young man called etc. chewing the plant etc. The other species of erigeron have similar properties espec. E. phil. Various recipes are given for diarrhoea in children Ex mag. zfs rhei gr. 8 [illegible] zi ess. pep. gtts 6 gum ar. zi The popular remedies are generally absorbent [illegible] mucilaginous astringent etc. Much benefit may often be derived from copious mucilaginous injections mutton broth is the most popular probably other broth (fat meat) would answer still mutton suet is less apt to become rancid. It is thought to be useful also as nourishment I have not though much of this may of nourishing Laudanum may be added Also laudanum & starch injections may be advisable to check the excess of the discharge It will generally be best to begin with about 10 drops of SS. though a teaspoonful may be required vide p. 2 [illegible] 2 12:l. Prolapsis Ani This is a troublesome symptom which sometimes occurs in diarrhoea. The protruded intestine should be immediately replaced. Most writers recommend to do this with a dry cloth, but this will irritate the sphincter ani & make it contract. The smoothest and least irritating article within my knowledge, is the crop of a fowl, or the neck of a bladder, turned inside out & filled with warm water # Afterwards we may apply astringent washes & injections of white oak bark or other similar articles, or of acetate of lead. The latter article may also be given internally in doses of from 1 to 2 grains. It will have a tendency to overcome the relaxation. Astringents are multitudinous & have had a specific [illegible], which proved to be the bark of [?strea] virginica At another time I had a specific sent me which proved to be viburnum sentago all the vib. are astringent Prolapsus ani “The part is relaxed and passes down and is then strangulated by the sphincter. For a permanent cure we must resort to astringents & tonics, but the part must be [illegible] by mechanical means If the intestine is not replaced, [illegible] or suppuration will be the consequence” “Take 1 bladder, cut off the neck, turn it inside out, fill it half full of warm water, and tie up the neck” “This disease was very common at the commencement of my practice but is now rare. The change has arisen in a great degree from the more correct notions respecting the proper management of the mother and child which now prevail. It is possible however that it may appear in [epidemics] and that case we should expect that it would appear for a time and the disappear # It frequently follows other diseases both in children and adults # According to the law of contagious diseases and that it is of no use to prevent it # Heat is a stimulus but too much of it produces a debility which may be [illegible] perhaps in direct debility “Since a free ventilation of nurseries has been practical the disease has been rare. laying aside the use of the preparations of alcohol has also been beneficial.” 13 Aphthae or Thrush White thrush from [illegible] (to inflame) This disease often appears within the mouth is then generally unaccompanied with fever. In some cases it is idiopathic but it more generally is a consequence of morbid affection of the primae viae # It is frequently found in adults of robust constitution which have been very much debilitated by previous that disease infancy and old age are most subject to it & in infants, as was just mentioned it is often an idiopathic affection In some families every infant is several with this affection. The vulgar error however, which very generally prevails that all children have the thrush at some sooner or late period other # is contradicted by the fact that many children as I have known never have the least appearance of it at any time “and it may probably in all cases, be prevented” The most feeble and delicate children are affected with the most violence, hence & from the fact of its being an affection of old age & a frequent sequel of other disease in adults, it may be inferred that this is a disease of debility & this [illegible] will be confirmed by the predisposing causes which we find to be, confined air, a very hot room & improper food# It is caused among the poor by bad air & among the rich by too great warmth & confinement. The fever likewise which accompanies it in many cases is of a typhoid character. # “Caused by neglect of the nurse by want of cleanliness & is often the effect of costiveness” # And have been led to prescribe remedies to prevent the thrush “commences on the inner part of the lower lip & corners of the mouth & extends over the tongue & inside of the cheeks & gums sometimes all these parts are affected & sometimes only one of them” “It appears in small eruptions or vesicles containing a whitish fluid resembling a coagulum of milk these vesicles often coalesce so as to form patches” “extend down the oesophagus to the cardia & here in all known cases it has stopped” Prof. Tully has seen p.m. [illegible] which the thrush the al canal [illegible] “The feces are sometimes covered with aphthous sloughs” “in its severest the eruptions are of a dark brown or deep red colour” “The alvine discharges are very acrid” 14 Symptoms – The disease is preceded by languor and sleeping This is so generally the case that it is common for nurses to say that the child is sleeping for the sore mouth In adults I have observed the same fact, & have predicted the appearance of thrush from the drowsiness of my patient # The symptoms of thrush are very obvious. It commences with white specks upon the lips #, angles of the mouth, & tongue effervescence. # In severe cases the specks in crease in number and size until they cover the whole inside of the mouth the throat & are found indeed upon the stomach x & throughout the whole intestinal canal though this is disputed. One thing is certain, whether these specks or flocculi extend throughout whole alimentary canal or not, viz. that they are found upon the rectum, agreeably the law that the orifices of tubes are most affected The white crust will fall off and be succeeded by one of a darker colour. The coats of thrush are often many times renewed & in this case the formation of a new one is preceded by unusually protracted sleep. A typhoid fever may accompany. It seems to be an eruptive disease determined [illegible] the al. canal. “In its milder form it is confined to some particular part of the mouth or to the mouth itself. The eruption is white & the mouth appears “as if a stratum of coagulated milk were spread over it” & but one separation of the curd like crust will take place. The general health will be but little disturbed” “In severer cases two or three successive crop are formed & the habit being unhealthy, the food innutrient, & the frame weak and atrophous, the under [surface] ulcerates and spreads & a low typhoid fever ensues” # “Your principal object should be to produce an excitement in the bowels by some mild medicine” # Because it is an eruptive disease however diaphoretic seen to be indicated & those which [illegible] action “The treatment is ordinarily a gentle laxative but there is a choice in the kind of laxative. Some practitioners recommend oily medicines, as butter, goose oil, pigs foot oil etc. But these articles do mischief As the vital powers of the stomach are weak, these oils will become rancid” # In such circumstances the oils become rancid & consequently irritate. I never allow oils to be given, yet it is a common practice to swab the mouth with oils, especially goose oil (or [illegible]?) # Chalk shd generally be preferred the other articles dissolve more slowly & may act in part mechanically” 15 It is thought that this disease has often been prevented, by giving soon after birth a teaspoonful of cold water & repeating the remedy every morning, for some time taking care also that the bowels be kept open There may be some foundation for this belief inasmuch as the disease is brought on by heat and debility. “In families where the children have uniformly been subject to this disease. I have recommended cold water as directed that the room should be well ventilated and the child not covered with too much clothing” In mild cases & where the constitution of the child is robust, a gentle laxative will be sufficient to remove the complaint # Castor oil is very often prescribed for it & it may be proper to five it to assist the operation of other cathartics But there are several objections to this article. It does not affect the secretions so much as other cathartics. It does not evacuate the contents of the bowels so thoroughly as others & it tends to # relax the coasts of the intestines, already in a state of morbid relaxation “It will not remove the mucus of the intestines” For mild cases magnesia is the best laxative where it can be given in sufficient quantities. If the bowels should not need a cathartic chalk or some one of the other testacious powders may be given “as [illegible] oyster shells, crabs eyes, crabs claws etc.” # Because it is an eruptive disease however, diaphoretics and articles which translate action seem to be indicated # “Give at first the clear liquor of this infusion and if this does not operate stir it up and give the substance (1) “After the stomach and bowels have been evacuated the ipecac should be given in small doses ¼ to 1/6 of a grain, to keep the bowels open, to produce a tonic effect, to determine to the surface & to prevent convulsion Ipecac has more claim to be considered as a specific than any thing else. It obviates the morbid secretions of the bowels it acts as a tonic never produces unequal excitement or other tonics & it does not like astrigents produce constrictions Whenever there is a tendency to unequal excitement it must be obviated or tonics will do no good” # I rely upon the ipecac though I use [illegible] sometimes especially white root asc. tul. # Indeed “if diarrhoea is present, prepared chalk is a good remedy as is also charcoal: the best form of which is burnt oak for this can do no mechanical injury” # “I have found this almost a specific” Since I have used this treatment I have not lost an infant by this disease” Ipecac in small doses as an alteration approaches as near to a specific in any remedy can # which is not to be expected # Astringents must be avoided, though tonics are indicated because they produce unequal & local excitement & stricture they must be given in the latter stages after excitement has been [equalised] A little borax may be given Moseley’s solut. zinc ziii al. zi [illegible] 1 pt 16 In the commencement of the disease if the symptoms do not indicate the probability of a severe case an emetic of ipecac is the best remedy Antimony has been recommended but it is not a safe emetic for children within the mouth Infuse [illegible] of ipecac in 6 teaspoonfuls of warm water & give a teaspoonful every half hour until the patient vomits or purges. # Ipecac has the advantage over antimony in its tonic and antispasmodic properties & in the mildness of its operation, never producing alarming symptoms # If the ipecac empties the stomach and not the bowels, a blue pill should be given of the size of from 2 to 8 grains. If this be found insufficient, it may be assisted by a dose of calomel, or magnesia or an enema (1) After the bowels have been thoroughly cleansed the ipecac should be given in small quantities a fourth or a sixth of a grain to determine to the surface & to prevent convulsions # If this dose moves the bowels too much, we may add “[illegible] or 1/6” one sixth of a 1/8 drop of Laudanum to each dose The absorbent powder or the white decoction may be given at the same time# Astringents should be cautiously avoided until the stomach and bowels been thoroughly evacuated # “& if there is much fever” Where this has been done we may make use of Moseley’s tonic solution, or cornus [circinata] [illegible] alba, or sericea or saffron safely & with advantage It is to be remarked that chemical action is prevented by the vital principle acting upon the food or articles introduced introduced into the stomach, and putrefactive or [acetous] fermentation if the vital powers of the stomach are [vigorous] This principle applies to vegetables Plants taken up in full blown in August and packed in live [sphagnum] will be preserved by the life of the sphagnum In thrush the powers of life are weakened & not only substances taken in but the secretions themselves are subject to fermentation hance the use of obviating the effects by alkalies limewater magnesia, chalk [illegible] absorbent powders white decoct. Rx. “To prevent the increase of vesicles of effervescences, syringe off the acrimonious fluid as well as you are able, by some diluent or detergent gargle and expedite the separation of the sloughs by invigorating astringents” vide Dr Good vol [illegilble] p. 30 “A little borax & ergot may be put into the mouth. But if the mouth is dry & parched, this and other astringent shd not be used. In such cases we should give mucilaginous substances as gum ar. slip. elm. or sassaf X 5 or 6 gr a drachm? of each in a gill of water # or viola pedata (parsley violet) or comfrey We must be very cautious about administering it to infants 17 To correct the acidity which often attends this disease we may administer prepared chalk or lime water & milk Or Rx magn. usta 10 or 12 fr. elix. pareg. xx gtts water zi given in teaspoonful doses every hour If the stools are watery and the child is robust give coct. ppt # vi gr. cal. 1 gr or the compd powder of chalk in doses of vi gr. or a small quantity fo rhubarb instead of the cal. For watery stools give dal. 1 gr & chalk 6 grs or compd powder of chalk It is too much the practice to scratch or rub off the aphthae in a violent manner with a brush or swab. As well might the cure of any other eruptive disease be attempted by violently rubbing or scraping off the pustules. Rubbing the mouth with a brush or swab until the bleeds is a cruelty which ought to be deprecated Still something must generally be done to the mouth in order to satisfy the importunity of nurses & prevent their mischievous attempts A little borax and sugar X is as safe as any thing If the mouth is dry it may be lubricated with muc. gum arab. slippery elm or sassafras twigs When the mouth is in a very high state of irritation probably a small quantity fo sugar of lead would be serviceable. I have not myself ventured to administer it to infants within the mouth For the proper local treatment of ulcers vide ulceration of the mouth From the sympathy which exists between these parts and the surface, tonics should be combined with diaphoretics I have given [illegible] [has] or [illegible] it is [illegible] observed by tonic and determines to the surface # It is mucilaginous sub-emetic & diaphoretic. It may be given freely as a wash or administered freely internally laxative diaphoretic soothing antirritant “The other [illegible] may be as good” The disease of which we have been speaking is a local disease 18 Ipecacuanha in this disease is emetic, tonic, diaphoretic etc. alterative & since I have used it I have not lost a single infant with thrush The viola pedata (parsley violet in some degree resembles ipecac is its qualities & may be internally administered in its stead # “give a teaspoonful of of the decoction” The peculiar kind of thrush of which I have been treating is a local eruptive disease of infants but as it appears in children more advanced it a critical determination of diseased action. It is not unfrequently a favorable symptom, particularly when it succeeds strong morbid action & [illegible] early in the disease In the latter stages & when the system is exhausted it is unfavorable For instance in hydrocephalus, when the whole mouth will sometimes become sore, and the disease seen to be translated to the mouth “from the brain to the muc. memb” In the latter stages of any disease not so fatal as hydrocephalus it is a very dangerous symptom of exhaustion “In cholera infantum it is a dangerous symptom. [illegible] there is not translation from [illegible] essential part” 18 ½ Eruptions in General Children of all ages are subject to various eruptions These are generally occasioned by the quantity or quality of their food. They are frequently cured by change of diet alone & the greatest attention should always paid to the diet is managing them Oily food particularly nuts, must be strictly prohibited, as they often cause eruptions. I have known some adults invariably affected with eruptions about the lips or other parts of the face after eating freely of walnuts Fish & poke week may likewise [illegible] the eruption We may use the tepid bath for the purpose of cleansing the skin. The frequent use of the [illegible] bath is important especially in chronic eruptive diseases of children & adults vide p. 21 & p. 20 For infantile [illegible] [illegible] p. 1831-2 of Good Case of a peculiar eruptive disease vide [illegible] [illegible] P. 1831 1 [illegible] art. The eruption was periodical, appearing at a certain hour every day At first a light coloured opaque elevation of the skin about half an inch log & a quarter broad like the sting of a bee or wasp. Soon after their appearance blood began to ooze from them & producing a drop which concreted into a scab, & at the end of 3 days fall off 8 or ten eruptions came out daily. Treatment was ineffective until a change of air & diet, which effected a cure “Child 8 or 10 yrs of age about 5 p.m. it would complain of a pain in the face then would appear elevation of the skin to the number of 10 or 12 the issue was treated as if [illegible] bark was tried also nit. sil. sulph zinc. arsenic & other minerals emetics cathartics new diet finally fruit was recom ate freely of oranges & was benefitted. Then change of air & travelling were tried or the first day the eruptions diminished & on the third disappeared In such cases try changes of mineral waters & dieting” 19 Red Gum Allied to thrush is that eruption called red gum The original word was red gown (from a sort of spotted red calico) which has been corrupted into red gum It is called by [Willa??] strophilus intertinctus It is a populous eruption & said to be peculiar to children but this last is doubtful The eruption is sometimes confined & sometimes diffused over the whole body. The papulae rise above the skin are distinct from each other & of a rarely contain lymph bright red colour. The vesicles contain by [illegible] only & terminate in scurf. Afterwards subsequent eruptions makes their appearance. The constitution is rarely affected. Physicians are not usually called unless the nurse is inexperienced Nurses give saffron Some physicians suppose this disease to be the same with aphthae. Dr [Willan] thinks they alternate. Dr Russell remarks “I think that aphthae of infants is of the same nature with those eruptions called red gum & differs in this respect that one disease affects the skin & the other the internal surface of the alimentary canal. Dr [illegible] thinks that this affection, preceded by sickness, arises from causes similar to those of aphthae, such as confinement, heat, irritable state of al. can. indigestion [illegible] If the disease be suddenly repelled from the surface, vomiting & spasmodic affections take place. Hence the European physicians Belonging to the primary [page] Probably the patient was not dieted so strictly as was intended & I recommended change of air Oranges however were beneficial. The was too fond of good living, fond of oily nuts There was a slight reappearance after it but of short continuance It was called [illegible], but improperly The eruption was preceded by a warming sensation of pain in the part. “Red gum is an eruption of fine pimples of a red colour affecting infants [illegible] within the mouth. It is a disease that rarely requires the advice of a physician The cure is much better effected by diet and [regimen] by the exhibition of medicines Still the physician is frequently called in and he must prescribe something if for no other object than to satisfy the friends In order any case give a decoction of saffron & snake root to keep the eruption from [striking] in & keep the bowels soluble with tinct. rhei compd tinct sennae magnesia, or other mild cathartics” 20 caution is not to expose infants with this eruption upon them to a current of cold air, or to plunge them into a cold bath. It is said that fatal consequences have resulted from such imprudence The child should be kept clean & be subjected to daily ablution of tepid water. Particular attention should be paid to the quantity & quality of its food. If the eruption should be repelled from the skin the tepid bath will be the best remedy This disease often occurs within the mouth & rarely requires the attention of the physician. [illegible] tone of the mildest of the eruptive diseases “We may give a decoction of saffron crocus? & snake root to prevent the eruption from striking inwards & keep the bowels soluble by mild cathartics such as magnesia & rhubarb. Still more will depend upon diet than upon medicine. Wine & water or one part milk & three water may be given” [belonging] to p. 18a “In managing most eruptive diseases more attention should be paid to diet than to medicine. In most cases it is requisite that the quantity of food should be diminished. If the food is milk, let it be three parts water, or substitute whey. Infants should take no animal food & no crude vegetables within the year. Oily food and the various kinds of nuts should be prohibited even for 2 or 3 years. A strong child in the country, with abundance of air and exercise might be indulged in such excesses with impunity when a feeble child in one of our cities would be destroyed by them” The eruption is so small as not to be observed It is not my object to treat of eruptions in general with minuteness but to give the general principles of treatment food etc. There are many eruptions met with [illegible] children which cannot be classed or be found described There is an affection of children appearing within the weak, which is not described at all. In three or 4 days after birth elevations of the true skin not of the cuticle upon the hands and arms & various parts of the body containing pus and [illegible] or as large, some of them as ½ dollar high [illegible] [fever] I have seen but few cases they were mortal. The books in such affections direct bark & tonics. The practice proved injurious. The disease as I have seen it has been inflammatory and required antiphlogistic treatment It may however be typhoid sometimes perhaps. If so it should be treated accordingly. I have seen but 3 or 4 cases. There were inflammatory. I prescribed in all these cases & from an analogy more fancied than real, between this & [illegible] Eruptions are generally caused by improper quantity or quality of diet. The remedies frequently get the credit of curing the disease when the amended diet cured the patient Oily & highly stimulating food should be avoided. All the nuts one of the worst is the pea nut 21 Strophilus candidus In this species of strophilus the papulae are larger then in any other of the genus. They are not surrounded with an inflamed base. They are very distinct smooth and shining & appear like little pearls under the skin of about the size of half a millet seed. They may continue for some time. A close examination is necessary for their detection. They appear on the bosom & chest They may accompany other diseases I have seen them accompany cholera infantum in the last stages & considered a fatal symptom [illegible] dyspeptic consumption a dangerous symptom The chest appearing to be covered with an oil surface, looking like particles of water I have seen persons attempt to wipe them off as if water had been sprinkled on the part Belonging to p 18 ½ Apples pears and fruits etc. Cleanliness also shd be strictly practised [enjoined] robust children, much in the open air, may have eruptions about the face mouth etc. with impunity when with the same diet delicate children, much confined, would have fatal eruptions, diarrhoea cholera infantum etc. The appearance of the [former] [have] [illegible] and the parents are often much alarmed. The disease is not dangerous however, & leaves no scar behind A scab is formed & the margin continues to suppurate and matter forms underneath “There is a thin [illegible] discharge from the part & the scab comes off leaving a thing pellucid [illegible]” The disease continues & this film is thrown off & the process is repeated 2 or 3 times It is sometimes occasioned by dentition sometimes it is an effort of the system caused by disturbance in the al. can. “A prejudice sometimes prevails with respect to this disease that it is an effort of nature & ought not to be checked It is a loathsome disease extremely unpleasant to both to the patient and the nurse & if allowed to continue some time it would not be safe to stop the evacuation, at least without keeping the bowels open” Some [Phys.] recommend partic [illegible] as specifics. Cal. or blue pill occasionally may be advantageous Buckthorn has been much celebrated in this and other eruptions It is drastic& hydragogue It is perhaps milder in form of syrup. Many families keep it. Half a dozen berries will operate If there is much plethora, the neutral salts may be given Magnesia also both for the indication & as a corrector I have known the muriatic ether much prescribed, but have not used it much myself, substituting for it mur. ac. as below 22 Crusta Lactea This is the [illegible] larvata of Bateman It appears on the lips, forehead & scalp in small pustules yielding pus, which eventually coalesce & form large loose scabs & perhaps extend over the whole face, down the neck and over the whole body. This eruption never leaves a scar behind it however long it may have continued. The skin is left smooth It is more unpleasant than dangerous, as the children affected with it are fleshy and otherwise health. When it has continued a considerable period of time, we must be cautious of checking it, as it is like a habitual discharge from an ulcer Treatment It is very common to give laxatives, such as syrup of buckthorn, neutral salts, magnesia etc. The sweet spirits of sea salt (diluted muriatic ether) is a very popular remedy. IT is given in doses of from 5 to 10 drops, diluted with water & repeated 2 or 3 times a day. I have seen this medicine given in hundreds of cases & am inclined to think it sometimes of service. It, at least give satisfaction to the parents & does no injury. If there is great irritability give 2 or 3 gr. of cal. with chalk. In cases where I have thought proper to remove the eruption. I have given the muriatic acid instead of ether, prepared in the following manner Rx mur. ac. zi alcohol zi Give [3] drops night & morning diluted with water make [oxyg.] oint. by adding the nit. ac. to lard until decomposition ceases, and the resulting ointment is tasteless. It has about the consistence of wax. Some add sulphuric acid but this is not decomposed & is acrid Sometimes the ointments seem to irritate & then we use [illegible] The best is the sulph. pot. zi to a porter bottle of water. Sulph. of soda does not materially differ, but it is unpleasant smelling like bilge water. In different cases apparently similar I have tried ointment & succeeded in one, but failed in another, & succeeded by waste I was led to adopt the use of sulphuret of potash from the analogy between its solution & the water [of] sulphur springs “We may with advantage make application of dry powders arrow root roasted flower hair powder taking care to give a cathartic when we check the discharge. We should pay particular attention to the diet both of the child and mother making the food weak & [simple] Laxatives will commonly be removed; a little magnesia & sulphur so as to move the bowels once or twice a day “A discharge like this may be checked with safety at the commencement, but when it has become habitual it should not be stopped unless a drain is made & kept open in another part.” 23 For this eruption I have found the oxygenated ointment, very efficacious in removing the scabs & healing the sores It is always safe if well prepared. ‘It is made by decomposing nitric acid with lard’ Perhaps the [citric] ointment (nitrate of mercury with lard) may be equally efficacious, but it is less safe. A good ointment may be made by mixing calomel zii with simple cerate zi or mutton suet zi The sulphuret of potash is one of the best remedies for this & other similar affections Dissolve zii in a pint of water & give a table spoonful night and morning also let the part affected be washed with a solution of twice the strength “It sometimes [illegible] two or three days and [illegible] [illegible]” Some prefer sulphuret of soda sulphuret of lime would also be equally efficacious Such solutions small like bilge water & are analogous to the water of sulphur springs I have sometimes used the sulphuret of pot. as an unguent. Sometimes liquid applications & sometimes unguents will succeed best, & if one fails we may try the other “Calomel ointment may be applied about the edges” If the eruption should suddenly dry up & fever ensue, a dose of calomel should be given & be followed by a few drops of antimonial wine 3 or 4 times a day or a small quantity of ipecac. White hellebore may be given Sometimes the eruption degenerates to a phagedenic ulcer. In such cases I have used charcoal eternally also a variety of poultices. I have seen much The const. irr. may expend itself upon the skin or upon the gland. syst. or upon the al. can. etc. We must be cautious about suspending them suddenly “It is important in all kinds of eruptions to keep the skin clean and soft & to effect this we should prescribe the warm or tepid bath, every day or 2 or 3 times a week. It removes itching and irritation, is always safe and almost always beneficial” May be caused by teething or by food etc. Such things often withstand various remedies & hence are prescribed for very empirically 24 benefit derived from the application of roasted flour. It absorbs moisture & excludes the air Eruptions attendant upon Teething Children are very commonly affected with eruptions when teething. They generally put on the appearance of a fine rash, but sometimes consist of distinct pustules containing matter As they are symptomatic merely, they require no particular attention to be paid to them & will disappear when the teeth get through. The worst consequences might result from their sudden suppression; as if this mode of action by which the system relieves itself from the irritation of the teeth, be interrupted, there is great danger that the system will relieve itself by morbid action of the brain, or other parts more essential to life Eruption resembling the itch Another kind of eruption appears on children of one or two years of age. It sonsists of distinct pustules like those of chicken pock, which form a scab, continue to inflame about the edges & contain a watery fluid It usually makes its appearance in summer & if not cured disappears spontaneously at the commencement of cold weather It has often been mistaken for the itch, and attempted to be cured by [?dock] root, but without success. The sulphuret of potash used as above is a good remedy The tepid bath is apt to be neglected but shd not Dock root often fails in this. It is often very successful in children’s eruptions. It is a very old remedy (centuries) Sometimes goes into oblivion & is again revived Prof. Smith thought most highly of R. patientie 6 feet high in gardens. Woodville mentions R [aquaticus] I know not that either is better than our [common] [illegible] I prefer the [Robtusifoli??] or [horserock] It is acrid and acts well when ext. [applied] and is good int. like rhub. R. crispus also has about the same properties but is milder. R. sanguinea is kept by many for it is as a specific for cutaneous eruptions. called also jaundice root & used in jaundice I have used them all and cultivated than all The leaves of the R. sanguinea have all red veins. You will often have such cuticles exhibited to you in families and be [illegible] of about them. Hence the importance of a knowledge of their prop. I have never known them in any but the children of [foreigners] I am inclined to think the taint may be dormant. The eruption at first resembles what is called “horn pock” “sometimes resemble a [illegible]” The nurse was changed & though the new one was health yet the ulcer appeared on her nipple 25 I think this kind of eruption might be cured by diet and the warm both. In all cutaneous affections the warm bath is very important to relieve the skin from every thing that may obstruct perspiration Eruptions & other irritations of the skin translate action from the viscera. Where irritated action exists in the viscera they are symptomatic Gutta rosea of drunkards is an instance of translation of action from the liver “When a cutaneous eruption appears we may generally apprehend that the al. canal is disordered” I cannot too strongly enforce attention to diet. Nothing will avail without it Venereal Eruptions These appear infants born of parents tainted with syphilis, though they may have no symptoms of it at the time of the birth of the child. Some physicians are of opinion that this child may inherit the disease from its ancestor the parents having been apparently free. The eruption appears in smooth hard, circumscribed elevations of the skin of about half the size of a pea 7 resembling a wart before it has seeds. They continue to increase slowly in size for two or three weeks, & become soft, containing a watery fluid in [honey] like substance Subsequently the skin gets rubbed off & leaves an ulcer with ragged edges & sometimes resembling a chancre which is very difficult to cure. I have known one instance in which the ulcer was communicated from the child to the breast of the nurse. Children affected with this Eruptions sometimes depend upon morbid state of the liver analogous to gutta rosea of drunkards Prescribe to the liver “The disease often proves very obstinate” Mercury does not seem to act as in the primary disease Corr. sub. given in this way is as safe as any other article The bowels should be kept free “I think the sublimate acts more on the skin & is therefore preferable to other mercurials” The plantain was once celebrated for the cure of cut. aff. I have known the plaintain in this way apparently cure after mercurials had failed Still the mercury might have prepared the system The plantain is an old English remedy for bites of spiders etc. It is treated of by Woodville & [Willan] It has as little acrimony I have some confidence in its efficacy. There is an old story about a snake & [spider] I have known nondiscript eruption which had resisted the prescription of several phys. cured finally by diet & change of air 26 complaint have a pale & bloated appearance & the powers of life are feeble Treatment. Change the nurse if derived from her Give corr. sub. in doses of 1/30 or 1/40 of a gr. Give the blue pill in moderate quantities but it subl. is better Give the tepid bath. Try the preparations of iron, such as the mur. ferri, or tartr. ferr. or the alkaline solution of iron. This complaint is not so easily cured as the primary [illegible]. Sometimes it will resist the operation of mercurials & all the treatment for scrofula. In this case send the patient into the country & try simple vegetable articles especially the expressed juice of the plantain (plantago major) externally and internally. It is a popular remedy for poison & is apparently valuable. I have known patients cured by the use of this, and of the air of the country. Still I think its main virtue to consist in its bland & mucilaginous quality [In these cases the whole lymphatic system is disordered & deobstruents are indicated. Now the expressed juice of most green vegetables id deobstruent. For instance the farmers make use of green rye in the spring for this purpose] Perhaps the expressed juice of the green plantain is deobstruent Infantile Erysipelas is an improper name vide Gray [illegible] of Erysipelas Good’s is an entirely different disease and his account will completely [illegible] Corresponds perhaps to the rose of the W.F. Goods account of the rash may do pretty well The infantile erysipelas of Europe described in the books is a different thing # Resembles shingles this is accompanied with fever The primary affection is of the al. can. therefore the attention is not to be directed exclusively to the skin I commences with [illegible] [illegible] you are to prescribe to the fever [illegible] This disease is distinguished by the eruption resembling a rose in the shading off of the colour from a dark rose to a light colour & in the concentric circles As I have seen the disease the rash has appeared in patches about the [illegible] thighs principally & the local affection gave no [illegible] and was trifling while the constitutional fever was severe and dangerous. The fever if not broken up in the commencement will resemble a severe case of [autumnal] remittent I have found no satisfactory account of the disease in the books, not even in the W. P. writers. I have however been informed a conversation with W. Indians that the rose is one of their most severe and dangerous infantile diseases fatal in a week and is treated by a vigorous administration of calomel # I have never seen the infantile erysipelas described as occurring in the European lying in hospitals contagious & terminating in gangrene I have seen common erysipelas upon infants however 27 Infantile Erysipelas The classification of this disease id doubtful. It answers tolerably well to the exanthesis roseola of Good “but [illegible] febrile” there is no species in Bateman & Willan which corresponds to it Efflorescence in blushing patches, gradually deepening to a “dark” rose colour, mostly circular or oval, alternately fading & growing brighter chiefly on the legs with irregular appearance somewhat like concentric circles if the patch is not circular the general circumference This is a disease of rare occurrence with us I have met with three or four cases. It is a severe and dangerous disease, apparently the same with the dangerous rose of the W.F. As it appears with us it is very different from the erys. that described by European writers & which is sometimes epidemic in their hospitals. In children in this country it is generally a disease sympathetic with a morbid state of the bowel The elevation of the skin is less than in erys. of adults the discoloration less deep in colour & the skin though a little tumefied is as smooth to the touch as if not diseased In the cases to which I just alluded, the erysipelas began upon the thighs & extended all over the legs. It was accompanied with considerable fever & a hot dry skin The colour of the efflorescence was purplish rather than red ‘We rarely see watery or bloody vesicles, as in other erysipelas’ I evacuated the bowels thoroughly with calomel (for the sake of the excitement rather than the evacuation) & rubbed the part affected The fever will much resemble that of infantile remittent “The spots are in patches from the size of a dollar to 5 or 6 times as large They are shaded in concentric circles from purple in the center to a lighter colour” “If the disease is not checked there will be increase of fever, constipation and tumefaction of the bowels irritation of the stomach affection of the brain, [illegible] death” Administer a full dose of calomel in the first place and repeat it once or twice. Work off the cal. with other cathartics. The secretion excited by the calomel is what we want. The cathar. subsequently given bring away Antimony in small quant. & nitre may be given until the liver is subdued “When the febrile symptoms run high pulse tense, tongue furred skin hot it is a very dangerous practice to apply discutients applications to the eternal affection Acetate of lead applied externally will probably translate the disease to the bowels” “Treatment I first give colored in full doses to alter the secretions to change excitement and promote evacuation, but do not depend upon it as a cathartic I then give [illegible] or [illegible] & [illegible] etc. to move the bowels I afterwards use the absorbants or alkalies, or ant. or iped. in small doses, as the case may require 28 It is attended with constipation & tumefaction & [illegible] of the bowels; with hiccup & severe fever, & may terminate fatally with severe coma “Pulse small & frequent child dies usually on the 5th or 6th day” “Dr Dewers says that in the cases he has seen the disease was not local but would spread rapidly over the body disappearing in one spot without leaving a trace behind it & breaking out in an other & perhaps a remote part thus changing from one end of the body to the other” Treatment. “Evacuate the stomach with an emetic, as ipecac” Clear the bowels thoroughly with cathartics, for the sake of the impression on the system. Give calomel in a dose of from 5 to 10 grs. If it do not operate within three or four hours repeat the dose. If necessary , work off the calomel with senna (or scammony?) adding aromatics if the stomach is irritable or with castor oil if the senna fails using also some laxative injection & the warm bath to assist. Then keep the bowels open with blue pill & “use some mild diaphoretic as aqua amm.” or give antimony from from 1/20 to 1/16 of a grain Pay little regard to the eruption and direct your attention to the bowels I have letters from physicians who have followed my directions & treated the disease not as a local one but with cathartics which testify the complete success of this plan of treatment. In the W.F. also where the “As palliatives after a strong impression has been made on the bowels by calomel, we may give sweet spirits of nitre, aqua ammoniae etc.” I have tried various either applic. without benefit I have “In those cases when the treatment wa local only the patients have uniformly died. I have not lost a single case to which I was called with commencement. I have conversed upon this subject with medical [illegible] out from the W.F. and find that the practice there coincide with mine” “When called to cases of some standing I have endeavoured to arrest the progress of the disease by a blister as [illegible] in gangrene & in the erysipelas of adults. The disease would extend beyond the blister just as if none had been applied” There is an erysip. affection which occurs about the head of children which resembles that of adults which I have treated with lead water 29 disease is frequent it is treated by the physician with calomel & cathartics. They give calomel 10 gr. & repeat it in 5 gr. doses until 20 gr. have been given I once saw a child with a swelling on one ankle supposed to have been produced by the sting of a bee or bite of a spider, which had resisted the operation of poultices & lead water. I gave cathartics but they did not operate, & the child finally died External applications of any activity should not be used, Still it may be necessary to apply something in order to satisfy the parents. The best will be roasted four “dried [illegible] [illegible]. Warm bathing will be very useful. If treated with lead water & cathartics not used, probably every case would be fatal. I have blistered in imitation of Dr Physick, but never with any advantage ‘If the disease be followed by diarrhoea give absorbents & aromatics such as compd powd chalk or white decoction. If followed by weak pulse etc. give tonics’ I have not lost a case when called early ‘This disease is supposed by some to be hereditary I have seen it affect infants on the scalp when it appeared to be a local affection merely In cases of this kind I have used lead water with [illegible] continualy advantage & without any evil consequences’ Cathartics however should be more or less employed in conjunction “afterward aromatics or tonics as the case may require” ‘It sometimes affects the brain’ [illegible] a more [illegible] or [illegible] intertrigo an attenuation & sometimes abrasion of the cuticle. The vessels forming the cuticle are diseased and the skin is formed in an imperfect manner It occurs also about the nates, [illegible] etc. where the skin folds upon itself & the air is excluded sometimes an acrid discharge Cullen thought it a very thematic affection. The skin looks like a new skin upon these parts. it arises from want of cleanliness & from confinement. The stomach may in a state of indigestion secrete an acid and the skin may secrete an acid. Exercise cleanliness treatment in general of eruptive disease When [illegible] flax they would burn a rag and put it in an axe & rub their finger on to harden the skin when chafed. A scorched rag is beneficial & use absorbent powders first nit. [illegible] might be used keep dry the parts Nurses apply “powder post” which is made by [worms] Sometimes it is a vesicular eruption which upon the head is called [farrigo] & in some situations is called ring worm To the [illegible] or intertrigo occurring in various parts the nurses sometimes apply the membrane from suet which is smooth keep off the air, prevents farther chafing and does well. The absorbent powders as starch alabaster etc. do well 30 Sore Ears This forms a very important subject in treating of the diseases of children. Nature has chosen the part behind the ear for eliminating irritation from the system. Under this head I shall speak of purulent discharges from the cavities of the ears & nose Slight blisters and ulcerations behind the ears of infants are very common & are in most cases, so mild as merely to require washing with cold water weak soap suds & with cold water, & being covered with a scorched rag or with roasted flour, to prevent irritation from the cap Frequently the discharge is acrid & excoriates the adjacent skin. Often a miliary eruption at the part commences the disease & is followed by excoriation Affections of the brain are sometimes relieved by a discharge from this part. The discharge is very important to children in time of teething & when affected with bowel complaints. If suddenly stopped fever may follow with full pulse, tense constipated bowels & fulness of the fontanelles & “often nearly all the symptoms of hydrocephalus” cold extremities Blisters behind the ears will generally restore the child to health When an infant is suddenly attacked with symptoms of hydrocephalus [illegible] disease, enquire whether it has had sore ears which have suddenly dried up, & if so, apply blisters behind the ears, for without them nothing perhaps will cure the new complaint. The same is true of old sore legs stopping of the [illegible] & other charges The theory of this, in all such cases, is the necessity, not The quantity of evacuation will not amount perhaps to more than a teaspoonful & the fullness of the fontanelles [rain] in the head & plethora is not owing to the quantity of fluid. The same plethora, pain in the head etc. will result from cessation of catamena which discharges will not amount to more than a table spoonful So you may bleed to the amount of pounds in cessation of a slight discharge for an old sore leg with out relief. while if you start the ulcer again by [illegible] or [mustard] the symptoms will be relieved Case of a man with ulcers on the legs of 10 to [20] years standing discharge stopped [illegible] pleurisy & aff. of liver the discharge restored by [illegible] blisters caustic etc. cure affected Sulphate zinc 10 gr. to oz or 2 oz may be applied Solution [illegible] sil. is one of the mildest application for irritated surfaces vide infra Oxygenated [illegible] is mildest & less apt to become acrid Sometimes when the aff is of an erysipelatous kind [illegible] relax the parts & are injurious Change the nurse also if necessary If the child is fed upon milk by hand, add perhaps a little magnesia or lime water Similar affections may affect the cavity of the ear & the cavity of the nose. If the cavity of the ear is affected in this way & neglected ulceration is apt to take place & the small bones affected causing deafness. First reject milk & water or carb. soda etc. [illegible] Finally if these means fail use stimulating injections myrrh finally [vit.] sil. In the use of [illegible] sil. external began with 5 grs to the oz & increase if necessary to xv or xx to the oz 31 of the evacuation, as is generally said, but of the habitual action of the system. This affection sometimes degenerates into a very troublesome ulcer, extending down the neck, accompanied with much pain & yielding a discharge so acrid as to excoriate the skin wherever it touches it Deep sores will be formed & the affection may terminate in gangrene & death In such cases it may be proper to apply emollient poultices of bread & milk; to which may be added poppy leaves, or pulverized stramonium seeds or ac. plum. Powdered gypsum is one of the best applications Alabaster gypsum is the finest kind Some apply red precipitate but gypsum is far better. Case in which this alone cured; Another physician advised red precipitate The oxygenated ointment if well made is a smooth dressing for them & is the best kind of ointment, where ointments do not disagree, as it sometimes the case. The bowels should be kept open with cal. or blue pill. It will sometimes be necessary to correct the milk of the nurse by administering magnesia & confining her to a simple diet Troublesome & sometimes fetid discharges on the internal surface from the ear arising from a kind of eruption may follow this eruption & may cause deafness if neglected I have known also the cavity of the nostrils & the frontal sinuses affected in the same manner. A cure may be affected in either case by exciting the discharge behind the ear though it may be necessary to keep it open for some time If this fails use (in addition?) milk & water Milk 2 part water 2 part lime water 1 part Tinct. of myrrh if the discharge is fetid & troublesome a teaspoonful to a gill, as an injection for the ear Sol. nit. sil. 1 or 2 gr to oz. water? externally Be very careful in watching the symptom Case of a young man who had had such a discharge for years checked by astringents [delirius] inflammatory fever ertc. bled cathartics etc. Porrigo galeata ([helvetea]) Cuticles below the scales dotted, shining Said to be contagious. I have never happened to see it so though I do not doubt the fact. I have never seen more than one in a family have it A very troublesome complaint The hair becomes pale, perhaps the roots are affected in which case mercury is indicated. Salivation seems to do no good I have seen it practised without any benefit Recent cases I have cured very speedily with oxyg. ointment. Any smooth substance applied to the part & excluding the air, will often cure as for in stance a bladder, or the membrane of suet what is useful also for [fret] Poultices do well, whether upon this principle or moisture changing secretion When a student I recollect there appeared a strong recommendation of poultices A physician of my acquaintance prescribed a poultice & left his patient. It adhered the hair grew into it and the hard crust formed a helmet indeed. It [was] a long time a period of week, before it was removed When it came off however, the disease was removed! 32 Tinea Capitis. Scald Head porrigo This is a local affection & yet much influenced by diet. Sometimes however it affects the system, or is sympathetic of a general affection of the system. The disease consists of scaly eruptions, eventually covering the head with a hard & generally brownish coloured crust. The hair often comes off. Cleanliness holds of course the first place in the list of remedies; the head should be carefully shaved and washed repeatedly with soap and water. Perhaps as successful a mode of treatment as any will be to shave the head closely and apply a bladder or affect skin in close contact with the skin. It excludes the air. Sulphuret of potash zfs or ai to a porter bottle used as a wash & given internally tablespoonful 3 times a day has cured the complaint in a few days mercurials or corrosive sublimate will be useful, but do not always cure. Sulph. prt. internally zii to lb i [illegible] ext zii to lb is [illegible] The ueast poultice is good, but care should be taken that it do not become dry on the head, which should be first shaved. The oxygenated and the citrine ointments have been found useful, as had also the tar ointment which is made as follows Rx tar ziv wax zfs sulphur zi or is Mercurial cathartics should be given from the first and particular attention paid to the diet. # vide last par. The practice in this complaint has been quite empirical & a great variety of remedies, have been popular. Veratrum viride & v. albus & [apocynum] [androsaem??] olium have used for external washes. Syrup of buckthorn is recommended as a cathartic. Muriatic acid Lunar caustic about 6 grs. to zi of water (rain water) well water may decompose it Decoction of cocculus indica, is given internally & externally. Cal. zii al burnt zfs red lead zfs z6 zifs spermaceti cerate head shaved & washed with soap sude every night and afterwards apply this ointment. It is given by [illegible] & Bates [illegible] & called Diet must be attended to Terebinthinate ointment as tar ointment Tar ointment is made of tar and lard or tar & simple cerate There is no difficulty in the diagnosis of the disease. You will be called to prescribe for scalled head and you will find that the nurses have not mistaken the disease. It begins with small pustules the matter [illegible] which is acrid and soon forms a scab over the whole head. The treatment must be principally local. But mercury may be given occasionally. I have not derived much benefit from the common mercurial ointment. Citrine ointment is good however. Also cal zif lard zi 33 has been used 3 or 4 drops in a wine glass of water Finally the sorts of the various species of dock (rumex patientia, crispa obtusifolia, sanguinea, aquatica etc.) have been much used All the species have about the same properties, being acrid purgative etc. They are given internally as cathartics, & externally applied, made for instance into an ointment, by pounding up the fresh root with lard. The following is a recipe Rx yellow resin zii best ale lb i finest flour ziii mix the all & flour thoroughly together & add them gradually to the melted resin. # The tepid bath may be used when this is used always take care to have a supply both of hot and cold water in order to keep up the proper temperature. Ipecac may be administered to equalize excitement in some cases, & as a valuable substitute for this article we can use the root of asclepia, tuberosa, which is expectorant, diaphoretic and laxative. “Vary the remedies according to their affect soften use decoct. rumex particularly r. obtusifol. called horse dock. It at firs increase, the irritation & secretion. Use it externally & internally” The excitement of the al. can. is affected also of the nervous system Various cutaneous aff. different kinds also of local inflammation, or erysipelatous phlegmous gangrenous scrofulous the inflammation varying according to the constitution scrofulous gangrenous I have frequently heard Pres. Dwight speak of the pain he experienced in cutting his wisdom teeth suffered extreme pain for a whole summer She did not appear to me to look like a person in the consumption I was puzzled [illegible] [illegible] I looked into her throat and mouth and found she was cutting r wisdom teeth # The irritation may continue for mouths, from the pressure upon the gum Those who commence cutting teeth at 10 mo. to a year or even later do not necessarily suffer more Delicate & scrofulous children suffer more 34 Dentition Among the causes of infantile diseases no one more claims the attention of the physician than dentition. The bowels and the nervous system are always more or less affected by it & to this cause we are frequently to refer affections of the lungs of the brain, of the ear, of the skin, of the glands, & of the cellular tissue in general. On this subject there is however a difference of opinion, for it is said by many medical men that children which are healthy # well teeth with as much ease as adults. Allowing for the peculiar irritability of [illegible], no doubt they do, but in granting this we concede nothing, for adults often suffer extremely from dentition. I well recollect the case of a Mrs Waters perhaps about 20 or 21 a married woman and the mother of said to have a [illegible] several children, who was supposed to be in the last stage a good deal of cough etc. had raised a little blood on consumption & upon examination & found was cutting the four wisdom teeth. The gums were divided & antispasmodics administered, when she recovered perfectly. # Case of Mrs Purcell’s child had been sick with diarrhoea and fever for some time a flush of fever coming on every day. I had previously extracted defective teeth from the [illegible] mouth. I now looked into the mouth lanced the gum over a double tooth gave no remedies The period of dentition commences at different ages times in different children, varying from the fourth to the sixteenth mouth, but most commonly in the sixth. The two central incisors of the lower jaw appear about the sixth month and are followed in about a month or six weeks by the corresponding teeth of the upper jaw. very [illegible] [illegible] [illegible] cases I have known a double tooth cut first in others an eye tooth in others all the teeth at once You must always examine to see what teeth are cutting You will perceive the gum swollen and harder Some children are born with teeth but such teeth re merely attached to the gum and are useless and should be removed Sometimes there is too much anxiety about dentition generally however not enough Case of a child mother called me insisted upon # irregular distributions of temperature are [illegible] [illegible] hot 5 [illegible] cold 35 Next come the inferior lateral incisors & after these the corresponding teeth above About the twelfth or fifteenth or 20th month appear the anterior molares & are soon succeeded by the cuspidati those of each kind in the lower jaw cutting through before those in the upper. Next we have the posterior molares. The last molar teeth are not found in the child & hence their name, dentis sapientiae. They appear from the 18th to the 25th year. The above is the order in which the teeth commonly appear, but they often come irregularly, sometimes the lateral incisores, sometimes the molares, & in a few rare instances the cuspidati appearing [illegible] Some persons never have more than two incisores in each jaw Occasionally we meet with families who are said to be destitute of teeth. I have known a family from Charleston, who had this peculiarity. The fact however is in such cases that the teeth exist but not rise above the level of the gums, so that they are not ordinarily seen Such teeth have this advantage, that they are not subject to decay & are also very serviceable. Whenever between the fourth and the eighth 2nd year? month symptoms of irritation exist, the cause of which is not obvious, the state of the teeth must be examined. The symptoms of difficult dentition are fretfulness inclination to bit hard substances, putting the fingers into the mouth, slavering, starting in sleep eruptions about the face & on the scalp, flushings in the cheeks. # hot head pupils contracted sometimes dilated sometimes losing their brilliancy In delicate children the eff. will be more chronic & in vigorous more acute The system relieves itself often by evacuation and this is considered often a good symptom as [illegible] there is a great flow of saliva. The system relieves itself by diarrh. by salivation by sweating [illegible] by every mode of equalizing excitement which is the great principles on fevers & indeed in most diseases 36 and cold feet, irregular paroxysms of fever, remitting fever vomiting diarrhoea irregular & green stools wine small in quantity & voided with pain or in large quantities and of a pale colour bloating of the hand feet and face contracted pupils. All the symptoms indeed of extreme irritation may be met with & we likewise find in many cases a tendency to phlegmonous inflammation suppuration in various parts of the body particularly in the ear. Case of a child who was thought to have an affection of the brain. A tumour was found under the arm. Sometimes dentition is accompanied with phlegmonous local inflammations in different parts of the body & suppuration of the glands about the ar by which relief is afforded Ricketty children cut their teeth more slowly than others but not in general with greater difficulty. The child must be held, and the fingers keep in the mouth to keep it off the tongue # The guard being made with a spring, so that when pressed upon the guard will yield and permit the lancet to descend (in the slit of the guard) 37 Treatment. The first and most important indication is to divide the gums with a gum lancet or other convenient instrument. The operation is not usually painful the child will even press against the edge of the lancet. The relief is often immediate and permanent Some relief may indeed be afforded by rubbing the gums with a hard & polised substance & by giving the child something of the same kind to bit, but the most effectual relief will be afforded by the lancet. The chief difficulty in the performance of the operation consists in confining the child. It may be done while the child is asleep & often without waking it. We must also be cautious not to cut the tongue To prevent this it would be better to make gum lancets with a guard # For the double teeth two incisors should be made & it may be necessary to make a transverse one in order to divide a band of a sort of ligamentory substance which confines the tooth. It is sometimes objected to cutting the gums in particular instances that, if it is done too early, the cicatrix formed by the healing of the incision will subsequently render it more difficult for the teeth to push themselves through This is not true for the cicatrix though apparently harder [illegible] less vitality in it than a part which has not been wounded and will be more easily broken through Solution of continuity is more easily made by disease in a cicatrix than in a part which has not been wounded vide J. Hunger. It is a common maxim that an old scar is apt to break out in to a sore The gums should be divided as often as there are any symptoms of irritation, until the teeth Some other diseased action may exist in the system, and the irritation of the teeth be superadded the lancing will only relieve the latter # For the gums having been exposed for a long time to irritation because [illegible], and perhaps ulcerated and are kept irritated by contact with the hard tooth 38 get through I have repeated the operation three or four times upon the same teeth. In some cases however cutting the gums relieves the symptoms only in part. Indeed the irritation sometimes continues after the teeth get through # “use astringents” If any disease from the causes attacks the child during the period of dentition it will be very important to remove all irritation from the latter source, for otherwise all the symptoms may be aggravated & a disease be rendered mortal which would otherwise have been mild. In children of a vigorous constitution dentition is often accompanied with inflammatory symptoms which require an antiphlogistic plan of treatment. Lancing the gums will then be useful as local bleeding & it may even be advisable to bleed from the arm though a few leeches behind the ear are preferable. It must not be forgotten that in infants, the bowels afford a great outlet to diseased action and to irritation: hence the frequent occurrence of a spontaneous diarrhoea. If the patient is costive or if it has a diarrhoea, a dose of calomel should be administered & if the bowels are soluble a milder mercurial, as blue pill may be given. During the whole period of dentition the bowels should be kept open by such cathartics as the state of the system may indicate, such as magnesia, rhubarb etc. adding aromatics if the system is relaxed and debilitated & chalk if there is acidity If a diarrhoea suddenly stops and vomiting supervenes, externally irritant to the [illegible] [surface] generally, injections, calomel The skin shd be kept moist for diaphoresis is one of the most powerful means of equalising excitement etc. If there is much perspiration you may depend upon op. alone but whenever there is much [unequal] excitement opium alone will not do well and ipecac shd be combined with it in small doses # Also by drafts to the [illegible], by local irritants to the skin generally also keep the bowels from remembering that there is no outlet to the brain 39 and the warm bath are to be used, as has already been mentioned under the head of diarrhoea Another & a powerful mode of equalizing excitement & relieving irritation is by diaphoresis. For this use the warm bath & small doses of ipecac & opium or of antimony and opium. Opium will always be useful to allay irritation & particularly if combined with ipecac or antimony, & always safe when there is no determination to the head Small blisters behind the ears relieve the symptoms of dentition & prevent the disease from terminating in hydrocephalus. # If these cannot be kept behind the ears mercurial ointment or cantharides may be applied to the same part. Nervines may be employed either with our without ipecac During dentition exposure to dampness & to currents of air should be carefully avoided & the patient should be kept warm X summer & autumnal epidemic Indeed the effects of it sometimes continue through the winter The desire often resembles spasmodic cholera in the premonitory diarrhoea & the sudden collapse 40 Cholera Infantum This disease appears in New Haven in the month of July August September & October. It rarely commences until the latter part of July & in October there are few cases except those which have commenced in one [illegible] other mouths & continued until this. Indeed cases are sometimes prolonged till the middle of November Symptoms. It begins in various ways; most commonly with diarrhoea, which may continue for days & even weeks without any very alarming symptoms; At other times times with violent vomiting & purging accompanied with high fever. The discharges from the bowels very much in their usually [illegible] from natural colour [illegible] [irritated] [secretion] appearance. Sometimes they are yellow, brown or green, sometimes in small quantities & slimy and bloody & at others in large quantities & watery, smelling like water in which putrid meat has been washed. Worms likewise may be found in all these various sorts of discharges “dead in the advanced stages” The disease is usually accompanied with great restlessness & often with severe pain, which increases by paroxysms at intervals of from fifteen minutes to two hours The pulse is usually quick and weak, the head hot and the extremities cold. The fever is ordinarily remittent but the exacerbations are frequently quite irregular The disease is attended with thirst often [illegible] and after drinking the child vomits. The eyes often appear languid and hollow During the whole progress of the disease [volvulus] may occur Be on the look out for it “The termination of this disease in hydrocephalus I have reason to think is more rare than is commonly supposed. Many cases of this kind occurring in my practice, I have reason to believe were cases of volvulus Or varying from cholera morbus of [illegible] [remittent] bilious fever sometimes putting in the form of cholera of [illegible] at others that of remittent bilious fever 41 while in other cases they may have an unnatural brightness as in pulmonary consumption indication a high degree of mental [illegible] excitement “of bad symptoms” Sometimes the eyes are half open during sleep, as is indeed the case in various bowel complaints of children when severe we often find the diseased action translated from the bowels to the head and terminating in hydrocephalus. Volvulus also may be another termination. Sometimes the vomiting ceases for several days and then returns, while the diarrhoea continues the whole time Duration As to the duration of the disease, it may be very rapid in its progress & terminate fatally in forty eight hours, or continue for months, & the symptoms may vary very much during the progress of the complaint. A damp hot atmosphere will aggravate all the symptoms, while cool weather with the wind from the northwest will mitigate them. In different seasons also cholera infantum will have symptoms peculiar to the year, varying in this respect like other epidemics Finally when it proves mortal, the child is carried off in convulsions, or is worm out with emaciation & dies with aphthae while in some cases death is ushered in by hydrocephalus, volvulus & other diseases Causes. We may consider the cholera infantum as an epidemic sometimes an endemic confined to a particular season of the year analogous (in its grade of action) to the cholera morbus o f adult “This disease is perhaps most analogous to a remittent bilious fever varied by the peculiarities of the [illegible] [illegible] will see in [Jackson] all that can be said in [favour] of the opinion. The very fact that it is often [illlegible] disproves the opinion besides the fact that the disease does not occur at all seasons during the period of dentition The disease is affected by the state of the atmosphere being much aggravated by a damp state of the air always minded by a cool bracing northeast wind The kind and gentle excitement produced by nursing is important in chronic disease “Children should not be weaned till dentition is complete or till 1 ½ years & in the fall” 42 infantile constitution” Dentition has been considered by some as the cause of cholera infantum but to this opinion I cannot assent thought it is held by Dr Jackson & many of our most respectable physicians Dentition may indeed be an exciting cause; it often aggravates all the symptoms & accelerates the fatal termination yet in the winter spring & months it does not produce the disease of not unfrequently children are affected with cholera infantum without any appearance of dentition Worms sometimes make their appearance during the progress of the disease but they cannot be considered as a [illegible] or cause of it. When they exist during the complaint the irritation which they produce must be obviated by such anthelmintics as are not contraindicated by the state of the system. “I think I have seen the [illegible] productive of unfavorable effects.” The cholera infantum probably arises from the same remote causes as the (cholera morbus) & the bilious remitting fever of adults such as damp hot confined air (which can be counteracted only by exercise in the open air) want of cleanliness & bad diet. Improper food may be both a remote & an exciting cause & the same is true of a bad state of the atmosphere muggy or [illegible] of inequality of temperature & exposure to cold. The predisposing cause produced by these remote ones is debility Children weaned in the spring are mor apt to have this complaint, & do not bear the disease so well as those at the breast. I would therefore advise that in places where cholera infantum prevalent. children should be weaned in the fall 43 Some consider malaria the cause Like dysentery this is a disease translated from the surface to the first passages. The fever is of that kind which Sydenham calls febris introversa the action being of an irritated kind in general & rarely of an inflammatory Commencing at the skin & breaking up the balance of the system by obstructing the perspiration the morbid action is transferred to the mucous membrane of the intestines & involves the liver, pancreas & all the glands immediately sympathizing with them. Indications. The indications are 1st To evacuate the first passages; if this has not been already done by the disease itself 2ndly To translate action to the surface & in general to equalize excitement 3dly To excite healthy secretory action and regular peristaltic motion of the bowels 4thly To avoid the causes of irritation and to remove irritation when it exists 5thly To restore the tone of the system & particularly of the stomach and bowels 1st When the disease comes on like the cholera morbus of adults, the stomach and bowels are sufficiently evaluated by the disease generally when the phys. is called and no evacuation s are to be used. It is to be treated like cholera morbus with aromatics as essence of peppermint, with Laudanum We must be careful not to prescribe for the [name] of the disease nor necessarily pursue the plan of treatment generally proper. Often you will find the patient so much debilitated at first as to require stimulants & acrids When we have the collapse stage and a collapse may recur in any disease then the practice of the nurses is correct in acting on the skin Some recommend large doses of cal. [illegible] much smaller the [common] Dr Jackson recommends large doses common in the commencement. Dr [illegible], 1 gr. doses and salt & water I recommend cal. from 1 to 10 gr Though sometimes small doses repeated may change the secretion better than large, yet often a large dose will operate more kindly, then a small one [which] merely irritates “Dr Dewers recommends injections of salt & water 2 or 3 teaspoonfuls to a gill, instead of cathartics. Repeat the injections till full catharsis is produced the morbid action is changed, by translation of excitement from the stomach & small intestines [illegible] [illegible] with cal. ¼ gr. every [illegible] to alter secretion 44 with counterirritants, as mustard, horseradish & brandy on the epigastrium & abdomen with the tepid bath & with injections of starch and laudanum. But when it attacks with a diarrhoea, accompanied with occasional vomiting unless the constitution is very feeble constitution [illegible] extremely delicate the stomach should be evacuated by ipecac and the bowels by calomel or blue pill To vigorous patients & often give in the commencement six grains & would not hesitate to give 10 grs of calomel & an hour after give from one to ten grains of ipecac according to the age and vigour of the patient for in this way the stomach and bowels are more thoroughly evacuated than by giving the calomel after the ipecac has ceased to operate In some cases a single dose of calomel will thoroughly evacuate the bowels, but in others it will only remove the contents of the stomach and small intestines into the colon & a dose of castor oil must be given or one of senna with aromatic seeds The southern physicians, make less use of cathartics and depend much upon stimulating injection, as of salt & water 3 teaspoonfuls to a gill. This practice does not succeed well with us. They also give smaller doses of calomel. This also I cannot approve for a large dose of calomel, ten grains for instance, will evacuate the bowels copiously and kindly, when small ones produce scanty stools, with irritation of the stomach and tenesmus. I may mention also that the French expectant plan of treatment adopted in Philadelphia will frequently be utterly inefficient. Where excited has not been equalized, calomel or any other cathartic may act upon the duodenum only and not produce Such facts as there have been given rise to the opinion that the disease arises from stricture but then the al. can. may be subject to unequal action as much as the skin # a castor oil with elix. sal. aa zi every 2 hours # Yet this practice shd not be adopted indiscriminately where there is weak morbid action accompanied with coldness of [surface] etc. the exhaustion of cathartics will be injurious This is the most important principle in the cure of diseases Sometimes cath. cure the diarrhoea, where the action is unequal. For instance the lower intestines may be torpid and the feces accumulate, the bowels above may be irritated and a diarrhoea of [small] liquid stools may pass by the feces 45 If calomel or any other cathartic produces watery stools in which are small pieces of feces of an ordinary appearance, and there have not previously been copious evacuations, we may conclude that a thorough evacuation of the bowels has been prevented by a spasmodic action of the intestines which has constricted them in places, & confined, perhaps a large quantity of fecal matter. Indeed this may be proved by the success of the treatment, which should be the administration of a dose of opium with a little calomel to change action followed at an interval of one or two hours by a dose of z ¼ and z ½ castor oil or elixir salutis teaspoonful #. It is of the first importance in all typhoid diseases, particularly in those affecting the bowels, that thorough evacuations should be made # 2ndly so translate action to the surface and equalize excitement This indication will be answered by an emetic at the commencement, as already directed & by small doses of ipecac, repeated throughout the disease, & also by small doses of mercurial medicines opium being conjoined in many cases, as will hereafter be mentioned. In some calls where there is much arterial action antimony is preferable to ipecac & the lancet or leeches may be indicated but such cases are rare This indication is also answered by applications to the abdomen of fomentations, with decoctions of aromatic herbs sinapisms, blisters, burdock leaves, horse radish leaves, ginger in spirits aq; amm or the Ulceration of the bowels is generally preceded by aphthae both are effects not causes of the disease “An [epispastic] should not be applied after aphthae have made their appearance. If the pat. is languid & sleepy we may suspect aphthae.” Diluents may be used Obviating irritation by opium is often necessary to have the proper effect of cal. for instance Give opium first & follow with cal. & often you will succeed in obtaining the effect of the cal. when you had failed before “Ipecac when it acts as a cathartic is more apt to produce fecal stools than any other article 46 terebinthinate oils An epispastic upon the epigastrium is very useful to relieve irritation of the stomach & to prevent ulceration of the bowels and aphthae. The warm bath will tend powerfully to equalize excitement will relieve vomiting, quiet restlessness, produce a uniform perspiration & if used at evening, procure a quiet nights’ rest. It may always be used and at any time, unless the patient is in a state of exhaustion. As a substitute for ipecac, the root of the asclepias tuberosa may be used. It is much used in infantile diseases as diluent, to determine to the surface & to promote expectoration. 3dly For changing the secretion of the stomach and bowels and keeping up a gentle peristaltic motion I have found small doses of mercurial cathartics with ipecac of opium superior to all other remedies. If any article deserves the name of a specific in any disease, it is ipecac judiciously administered in cholera infantum. It relieves this disease with more certainty as certainly as than cinchona does intermittents. It may be observed however that a man successful with one remedy only m ay be compared to a mechanic, very skillful with a pen knife! My method of administering the articles is the following. For a child four months old, mix 4 gr. of ipecac & 5 drops of laudanum in twelve teaspoonfuls of water & give a teaspoonful every fourth or fifth hour & at the same time give so much of the blue pill as to You will know when the blue pill begins to have its appropriate effect by the change in the color of the stools Pills of blue pill may be given without much difficulty to children there is little taste except of the saccharine matter. They may be given in food [illegible] dried huckleberries which I have often called for in the country where there was difficulty in administering remedies. There is often great difficulty with respect to this. A child will often scream at the sight of the doctor Opium to allay the irritation of the stomach and prevent the ipecac from being thrown of Ipecac to equalize excitement & determine to the surface Ipecac also, to qualify the opium # Or if this cannot be done, introduce a paste of opium just within the sphincter # Case of a child in a family where 3 or 4 children had previously died of chil. inf. [Lax] & [illegible] habit etc. I commenced the treatment with the pill and ipecac I treated it mildly giving blue pill instead of calomel N.B. For such cases [illegible] 47 procure an evacuation from the bowels two or three times in [never twice] in the twenty four hours. For a child a year old take twice as much ipecac & laudanum with the same quantity of water and give it in the same way. Sometimes three times the quantity of laud. will be necessary; for instance if the child has been in the habit of taking it or if the diarrhoea is very urgent If the diarrhoea is urgent, it may be necessary to administer injections of starch and laudanum & to apply to the abdomen ginger & grandy volatile liniment poultices or other irritants The enema may be made with three table spoonfuls of flour & about 3 or 4 times as much laudanum as you give by the mouth say 10, 15, or 20 drops. # I prefer flour to starch because the foreign starch often contains acid. The chalk mixture or white decoction may also be used. # “Children of a bucophlegmatic temperament and lax habit are very apt to have this disease & with them I have sometimes commenced the treatment by administering blue pill & ipecac.” The success of this plan of treatment will be strikingly shown by the following case. A child 10 months old was taken sick in this town last summer, with cholera infantum, grew worse and was directed by the physicians to be carried into the country Unfortunately the child was carried to a situation not more elevated than N. Haven & while there its strength decayed and all its symptoms were aggravated. The parents despairing of it recovery returned with it to N. Haven & sent for me with a request that I would do something to alleviate its sufferings On recovery from the disease they usually crave [salt] food and salt is a grateful stimulus 48 I found it in a state of emaciation, with hippocratic countenance frequent vomiting, urgent diarrhoea, with stools fetid, watery and containing some slime and mucus, & leaving streaks of blood upon the cloths. The countenance and gestures, expression of great anxiety, and there were frequent paroxysms of extreme distress. I directed ipecac 5 gr. & laud. 10 drops to be put in 10 teaspoonfuls of water and a teaspoonful to be given once in four hours flannel wet with ginger and brandy to be applied to the bowels & gave 5 oz. blue pill, & ordered the diet to be of arrow root flavored with a little brandy. After the second dose the vomiting stopped, the stools became less frequent & within 24 hours the complexion of the stools was much improved. The next day the same medicines were continued and four drops of the tonic solution with a little brandy and water. On the fourth day from my first visit, the child began to relish salt fish, which was allowed Capt. Dennison’s children To correct fetor in the stools we should give charcoal. Carbonic acid, by injection, is given for the same purpose. The mode of injecting carbonic acid, is to place chalk & vinegar in a bladder, and force the gas into the rectum, as it evolved. “This is recommended. I have tried it but not very thoroughly” But if vegetable food undergoes the acetous fermentation it shd not be used. The putrefactive fermentation however is more injurious than the acetous 49 4thly The most common cause of irritation is dentition The gums should be often examined, & be divided if they appear at all swollen. All kinds of food that is hard of digestion should be carefully avoided though for children somewhat advanced perhaps a small quantity of ripe fruit may not be injurious If the child has not been weaned the milk of the mother will be the best food; for those children’ who nurse are more apt to recover than those that have been just weaned. The act of sucking is highly soothing and gratifying & operates like a nervine medicine. The best food for children that have been weaned, will be arrow root, with a little brandy or wine as a condiment & as a substitute for this & similar articles from the shots, we can direct a porridge made of roasted flour. If in the latter stages of the disease the child craves any particular of food, as salt fish, or salt meat, or wine or brandy, it should be given, & all kinds of medicine laid aside if the stomach leathe3s them; for strong disgust will debilitate by exciting nausea. Frequently however we can succeed in preventing this effect, by a different mode of administering the medecine the sight of the spoon for instance may may give rise to the loathing & nausea. With respect to food we may lay it down as a general rule in such cases that when the powers of the stomach are so weak that food must undergo fermentation in it, vegetable diet should be preferred to animal. For local irritations, various applications should be made & various articles administered, especially in the latter stages “Tea juice? boiled beef a teaspoonful with pepper & salt is grateful frequently & checks vomiting but at first vegetable preparations are better” vide supra The chalk mixture made with a little opium in some cases or with astringents etc. a valuable [illegible] 50 of the disease or when we are compelled to try a variety of remedies. When there is unequal excitement & unequal temperature blisters may be used. Blisters sometimes produce perspiration. To relieve irritation of the stomach effervescing mixtures may be drunk, they are often more grateful. [illegible] we may fill the stomach where there is vomiting and dilute its contents with a tumbler of wine whey I have often succeeded with it with a teaspoonful of aqua ammoniae in it as being thrown up will be no objection. If the disease commences with much irritation in the stomach, it may be useful to overcome it by counterirritation in the rectum produced by an injection of soap suds or of salt and water 3 teaspoonfuls of salt to a gill of water, for a child a year old. Dr Dewers relies must upon this latter article in the commencement of cholera infantum and repeats the injections until the bowels are fully evacuated. He likewise recommends small doses of calomel, a quarter of a grain for instance repeated once in an hour until the bowels are evacuated. In cases of irritation of the stomach & torpor of the liver & portal system, this practice of salt & water & small dose of calomel does well. In chronic cases he gives magnesia rhubarb & opium. With respect to small doses of calomel it may be further observed that they will not answer when the intestines are much coated with mucus & that in some localities they do not answer so well as in other places. On the shores of lake Erie for instance the physicians are obliged to give large doses of calomel than we give There are cases in which small doses seem to irritate & large doses operate kindly “In the latter stages Rx magnesia grs 4 SS gtts Rhei gr i.” C. Florida not so pleasant but loses its mawkish & herbaceous taste by keeping (like peruvian bark) The spiraea is though less inclined to act unequally in this state than most other astringents If one astringent wears out try another Oak barks Rose [illegible] (salix [illegible} “A valuable popular remedy” has mucilage combined seeming to resemble ([illegible]) [illegible] was formerly much used but is now superseded by native articles It is well known that because These astringents are often prompt up is specific [illegible] virginica was specified good [illegible] & [illegible] it e.g. viburn. lentigo, raspberry, blackberry, [illegible] [illegible] root decoction recommended by Dr Rush thought to deter to [illegible] used by many) [illegible] bark has [mucilage] There is apt to be a paucity of [urine] in this disease as well as in Diarrhoea & dysentery and then diuretics are indicated and are highly valuable 51 5th When in the latter stages of the disease the principal indication is to restore the tone of the system & particularly of the stomach and bowels we must make free use of tonic and astringents. Moseley’s tonic solution will be one of the safest and best articles in this stage. If the bowels, by a habitual action keep up the diarrhoea, astringent will be more specially indicated such as the compound tincture of vitriol. I prefer however, the cornus circinata to all other articles C. servicea (red [illegible]) C. [illegible] C. alba nearly allied Of astringent vegetables we can make choice from a great variety which are indigenous & common. All the various species of viburnum all the [potentillas] & the roots of the strawberry to say nothing of the bark of the oak & indeed most of our forest trees, are astringent & may be used The spiraea tomentosa is much used in decoction or extract All the species of [illegible] are astringent & the C. [rivale] is a most valuable article; as is also the geranium maculatum, which may be be given in wine & then we shall have red wine. The sttici limonium (marsh rosemary) is not so agreeable but is frequently more efficacious specially if the mouth is sore. Its taste resembles that of salt mud. When given internally, it is boiled sweetened & has a little wine or brandy added. It is also used as a wash in case of the supervention of aphthae. The erigeron canadense, called colt’s tail & strangury weed has been found a valuable article in the latter stage of this complaint and of dysentery given in decoction. It is acrid pungent like [illegible] bitter & stimulating & acts also upon the kidneys as a diuretic. It seems likely to prove a Give it in decoction or in milk which will cover the taste of it Balsam of copaiba or turpentine cannot be combined with mucilage so thoroughly as in the white pine bark in milk & water diuretic & [sheathing] to the bowels I have often used the expressed juice of spearmint as in diarrhoea q.v. It is important in long continued bowel complaints of children that the medicine shd be grateful The diuretics are useful both in children and adults (dysentery diarrhoea & cholera infant) because there is a paucity of urine and acrid irritating secretions In some cases of exhaustion we give opium constantly in small quantities to keep up the [illegible] Mucilages marshmallows or substitutes for which hibiscus palustris hib. syrica hib. [illegible] hib. (rose of [shora]) Mucilages by stopping irritation are diuretic 52 a valuable article in the latter stages of bowel complaints provided there is not too much vascular action. It has been long used, vide Barton, the N.Y. Medicophys. Transactions etc. In 1790 an itinerant came through N. Haven offering to cure the dysentery; and attracted a good deal of notice. It was found that his [illegible] consisted of this article. The other species of erigeron have similar properties. In the latter stages of the diarrhoea mucilages should be given. They made of any of the various in articles in use, but perhaps the most valuable mucilage, will be that made from the inner bark of the white pine, which will furnish a terebinthinate principle in addition to its mucilage Often in the latter stages of the disease, great benefit will result from supporting the abdomen by a bandage and a plaister of white [diachylon] and opium or a soap plaister (of [illegible] & soap) 2 parts sp. 4 pts plaister In extreme exhaustion & debility from the long continuance of the complaint with cold extremities, aromatics and stimulants may be required & we may give spiced tea spiced wine or brandy in small quantities, or the white decoction and apply cloths dipped in brandy to the abdomen & to the extremities Nothing has more affect upon complaints of the stomach liver & bowels than the state of the mind as we see in dyspeptics The We are apt to suppose children not subject to notice of [illegible] children [illegible] mental impressions. When the matter has been dissolved in grief & abandoned to despair I told them to tray as a last resort carrying the child in a hack out of town the excitability was entirely gone the child might as well die in the back as any where strange advice On the top of the [illegible] about two miles out lifted up the child [sound] trees grass birds, etc. opened its eyes before this had lain with eyes half closed noticing nothing 53 Finally when every form of medication seems to fail, our only remaining resource will be change of air. This is a most powerful remedy. The physicians of N. York and Philadelphia are continually recommending it. We are apt to suppose that in children it can be only the purer air & the exercise of travelling that produces a good effect, when they are carried from home for their health, but on the contrary the change of scene seems often to have a more powerful effect upon them than it would upon adults. Children that have lain sick for weeks, instead of pursuing their accustomed amusement even though mere infants seem of ten to settle into a state of utter despondency from long confinement & the constant sight of the same unvarying objects around them, & appear to loath every thing offered to be done for them. This morbid condition of mind seems to be one directly opposite to that of nostalgia or homesickness & is to be relieved in a corresponding manner. I well recollect a child apparently in articulo mortis cold & vomiting nothing wd [illegible] the vomiting entirely beyond the influence of medicine or food. It was carried in a hack to the top of a hill without the town N.Y. [illegible] where it had a view of the sound, & the scenery of the country around. While there is brightened up vomiting ceased and took food staid an hour or more & then was carried back to town, where it finally recoverd. 54 The symptoms attending cholera infantum very very much and give rise to considerable variety of practice It is probably owing principally to this circumstance more than to any other that physicians differ from each other in their mode of treating it. Post mortem examination show that this disease affects principally the mucous membrane of the stomach & the small intestines; rarely the large ones. Sometimes coagulable lymph is found in the intestines but less frequently than in other diseases. Sometimes the mucous membrane of the intestines is thickening & according to Dr Jackson ulcers are occasionally found both in the small & also in the large intestines. The liver is usually enlarged without derangement of structure Ordinarily the brain exhibits no morbid appearances, unless the disease has made a determination to that part constituting hydrocephalus N.B. The remarks upon asclepias tuberosa introduced under the Head of [illegible] capitis probably belonged here Fever of the bowels Acute [illegible] of [illegible] Different writers give different names and do not always give the same symptoms. The European disease differs somewhat from ours. It is our infantile winter epidemic. Typhus infantum of Prof. [Tully] “Disease of the bowels bowel complaint, plague of the bowels, winter epidemic & [illegible] epidemic. Remittent bilious fever (at south) Musgrave’s spurious [illegible] fever Duncan III or IV” There is some [illegible] action but more of the character of irritation like other infantile fevers Rarely vomiting never diarrhoea in commencement The morbid excitement often extends to the lungs putting on the for [illegible] what is called in adults bilious pleurisy The disease is not common at this time though it was very much so formerly Probably it will return It is almost the only winter infantile disease & so common has it been also that the nurses call almost every disease in winter, of childr, by this name of choler. The dis. is to be broken up in its [illegible] by means various in various patients by a strong impression upon the stomach in a strong constitution but by an impression upon the whole system in the delicate constitution Comparison to a weight upon a [illegible] If applied upon one part only it will break it not if applied to [illegible] It is desirable that vomiting or at least nausea should talk place from the cal. In enteric 55 Constipation with Fever or Remittent bilious fever of children Musgrave’s spurious worm fever marasmus acutis This complaint has been known in N. Haven for more than 50 years by the name of choler. It is called in some places at the “It is unfortunate that we have no better [illegible]” eastward, the plague in the bowels. It is a common bilious “It affects however the duodenum & small intestines rather than the liver” fever produced by causes which operate upon the bowels a part of the system which in children more particularly invites Children are attacked by it from the age of 3 mo. to 2 or 3 yrs. febrile action. It is often inflammatory in its commencement Sometimes it [illegible] in the form of typhus Symptoms The pulse in the commencement of the disease is full, frequent & sometimes tense, the skin is hot and dry face flushed, respiration, short and laborious, tongue covered with a white fur, the abdomen fuller and harder, than in health, & the bowels costive; the urine small in quantity and high coloured & sometimes the fever is attended with cough & expectoration. This disease is a fever which often affects the lungs and always the alimentary canal & liver, the secretions being suspended and the bowels constipated. Treatment. This will be antiphlogistic in the commencement of the fever & the first indication will be to evacuate thoroughly the stomach and bowels. This will best be answered by a single dose of calomel of from 5 to 10 or 15 or even 20 grains for a child from four to twelve months old We shall thus produce a strong impression upon the whole alimentary canal & upon the system at large. In entonic cases and vigorous habits a little tartar emetic may be added to the calomel Usually the calomel excites both vomiting and purging, but sometimes it is retained on the stomach and has no immediate cases it may be beat to conjoin tartar emetic for this purpose. Sometimes the cal acts upon the stomach & duodenum & excites the action of the liver, and spends itself there, without producing catharsis Sometimes it is necessary to repeat 10 gr doses of calomel once in 2 hours until 40 or 50 gr have been given and cause them to follow with liquid cath. a [illegible] or jalap or scammony N.B. If there is great difficulty in giving medicine repeatedly, we may give powder of jalap in coffee or fermented liquor or we may give a teaspoonful of the tincture of (not briony root but pure jalap in milk & water which will not be tasted Feeble constitution must have the warm’ bath. # Rx senna zjs man zi senega zii anise seed zis liquorice zfs [illegible] ½ [illegible] This I have held the child with. remember large doses are needed Rx scamm. grs 2 or 3 chalk & diaphoretic antim. this was called Earl of Warwick’s powder & was kept in the shop here. Tart. emet. would be a more certain prop. of art. It produced violent vomiting. Scammony is better united with cal. however. # # Cautiokn about covering the [illegible] with a blanket vide # Cal. was finally substituted for the [diaph.] ant. This Warwick’s powder used to be a shot preparation in this town and parent would send for it. From the uncertainty of the strength of the diaph. ant. however, [dangerous] vomiting sometimes occurred from the use of it 56 effect. In the latter case a second dose may be given two or three hours after adding from an eighth to a quarter of a grain of tartar emetic for a vigorous patient Fifteen or twenty grains of calomel will often empty the stomach and bowels freely & remove all the symptoms. The calomel may however evacuate the bowels but partially & in some instances not at all merely moving the contents of the small intestines into the large ones. In such cases another cathartic is needed for completing the purgative operation If the calomel appears to have no effect, it should be repeated in 5 gr. doses every three or four hours, the patient put immediately into the warm bath & we should commence feeding the child as freely as the stomach will bear with the following R fol. sennae zfs, mannae zi steep in ½ pint of boiling water & if there is a cough, add senedae zii & rad glycyrrizhe zfs. If the stomach will not retain the mixture of senna the powder of jalap or scammony mixed with tea coffee or milk must be substituted, giving 4 or 5 grains in the intervals between the doses of calomel Injections vide p. should be given to assist the operations of the cathartics and repeated every 2 or 3 hours until the bowels have been thoroughly evacuated taking care however not to commence with injection until the cathartics have had time to operate When we have succeeded in procuring stools we shall find them to consist of viscid green mucus mixed with half digested food. Sometimes in the progress of the disease they exhibit the appearance of small pieces of membrane, of There is a membrane [illegible] inflammation of the duodenum similar to that of croup. This indicated by pieces of membrane preceded however by pain in the part obstinate constipation etc. This is a strong indication for calomel which however will not operate as a cathartic until the violence of the disease is broken Warm bath & injections will also be more particularly In some violent cases of the fever where calomel seemed to have no effect. I have known acid as lemon juice advantageously combined with calomel Among the cathartics and laxatives used in the second stage we have the wild liquorice or [illegible] [circa???] which was formerly a popular article and kept in families. It is diaphoretic and laxative and possesses and also deobstruent properties It is said that with this the Indians formerly [died] their porcupine quills # The acids are sometimes used in combination with mercurials I should not use them unless when mercury fails Sometimes it affects the ear & produces suppuration & discharge. It may terminate in effusion into the ventricle of brain. It may terminate by exhaustion Or may terminate in thrush “in which case there is a double translation 1st from the bowels to the head & thence to the mouth oesophagus & bowels 57 & of about the size of petals of peach blossoms, floating in a liquid of the same colour. Such stools as these latter are a sure indication that a farther evacuation from the bowels is needed vide p. 207 They are frequently evacuated by adults in bilious (or common cholic. If such continue it is well to vary the cathartic and give magnesia, or soluble tartar (peerlash & cremer tart.) or phosphate of soda, or any other neutral salt. generally the violence of [illegible] [illegible] & The blue pill may be substituted for the calomel & given three or four times a day, until the stools change their appearance or the mouth is affected, though this rarely happens to children under four years of age. These stools rarely have any smell & as they indicate a want of secretion I the liver & glands of the abdomen, mercurials are peculiarly appropriate. In some states of fever attended with stools of this kind I have known the free use of acids with mercury very useful # After 48 hours the fever generally remits, and sometimes it continues in the form of a remittent for six or eight weeks or more. Very frequently however it changes its seat in the course of 15 or 20 days & terminate in a phlegmous swelling of some of the glands or in phlegmon or is determined to the head & puts on symptoms of hydrocephalus, which are best relieved by blisters behind the ear, a place which is the natural outlet of diseased action in children. They may terminate naturally by a discharge of purulent matter from the cavity of the ear or fatally by effusion into the ventricles of I recollect two cases early in my practice, which continued 6 or 8 months. They were very violently attacked They continued 6 or 8 months coma Hence we should never despair In the latter stages it may be proper to give tonics or those articles which are called tonic very unlike the vegetable tonics however. They produce a [illegible] excitement Giving arsenic is no new practice It is a safe and efficatious remedy, when the dis. continues as a remittent It comes after cal. & tart emet. producing liquid secretions. If long continued it must be followed by bark to restore tone and obviate the debility caused by the arsenic Arsenic can only be called a tonic as it removes disease. It would never be given as a [illegible] is pure debility # # I have used digitalis, in the latter stages to allay irritation # In many cases the fever continues from habit & medicines have little affect. There will be an accession of fever every afternoon. Here give sol arsen 2 drops twice a day which is a full dose for a child ½ years old If this has no effect give it [illegible] times a day” 58 the brain; in two cases I have known them relieved by a thrush. If the disease continue a regular remittent without symptoms of hydrocephalus, it will be proper to give tonics, such Moseley’s tonic solution or if the fever intermits or remits Fowlers solution of arsenic the latter in doses of two or three drops the former from 4 to 20 drops, 3 or 4 times a day. I have known a child 18 months of age cured in this stage of the fever, in the course o f two or three days by taking 2 drops of Fowler’s solution 3 times a day. This article however is liable to produce edema or dropsical effusion & if it does we must substitute the tonic solut. (beginning with about four drops) or some preparation of bark. The dose of the tonic solution will depend upon the irritability of the stomach If irritable from 3 to 6 drops will be as much as can be borne After the inflammatory action has subsided narcotics anodynes are necessary to remove irritation and to procure rest We may use opium, either alone or better combined with ipecac or antimony # Indeed as the skin is usually dry antimony is indicated in almost every stage. The warm bath also is indicated in every stage except in the low typhus state of the fever when it would be too debilitating. Epispastics & irritants are useful in the progress of the disease, to translate action from parts essential to life & in the last stage also perhaps to keep up the action of the system. They may be applied to the abdomen if it is much swollen to the head behind the ears where there is danger of hydrocephalus & Avoid too much heat to prevent tumefaction of the bowels. Terebinthinates a [illegible] oil may be needed proper If pneumonic symptoms blister etc. “If the lungs are much affected, apply a blister to the chest, give expectorants, and pursue the treatment required in pneumonia. Senega & squills are good, but are too stimulating for the earlier stages liquorice anise” By this disease it is sometimes proper to do nothing and omit all medicines in mania etc. In those cases as I have had difficulty to persuade parent to do nothing. I have applied aloetic plasters to the bowels I think they have produced evacuations injections also can sometimes be given Case of a very [illegible] child [furious] parents passed in review before him with roasted apples pears etc. after 26 hours he snatched an apple relapsed in 26 hours they probably had over loaded his stomach however the same management finally succeeded afterwards of the patient recovered. vide p. [20?] The same season I had 3 or 4 more such cases of mania which required to be cured by fasting 59 a large one to the chest if the lungs are affected. “This disease is sometimes followed by thrush when an emetic of ipecac will have a good effect. If the stools are fetid charcoal should be given. If in the latter stages there should be tumefaction and pain in the bowels, the abdomen should be supported by a bandage. In the latter stages also a decoction of the inner bark of the white pine be useful. It possesses some tonic properties” Sometimes in diseases of children the mind is affected, the patient will take neither solids nor liquids & struggle till it is exhausted whenever an attempt is made to administer any thing. If that is the case in this disease we must use the tepid bath & we may a apply for purpose of moving the bowels, a large plaister of aloes and ginger to the abdomen Frequently this derangement & morbid revengeful disposition (according to Dr Rush an affection of the moral faculty is so great that we must wait even for 24 hours or more without administering any thing. It may require great prudence and judgment in such cases, to satisfy the parents. Before leaving the subject I may observe, with respect to the propriety of the course I have directed in the commencement of the disease, that if the cathartic which we administer first produces emesis we may be sure that the alimentary will be operated on, & also that we often require a remedy more powerful than the disease, just as in croup. “As to diet meat must be forbidden but sometimes salt food is craved. The weak chicken broth is good. The dis. is something very rapid & violent Fever as violent as the constitution could bear Collapse from the violence of action Parents considered the patient & dead After the mustard was applied as soon as the skin was reddened a blister was applied, which produced a sore 2 or 3 months in healing “In one hour pat. revived” Nervous system affected Irregular action such as after collapse of cholera Strong clonic spasms once in 15 min. “Pat. kept under a constant [narcosis]” Antispasmodics & tonics finally In two or three weeks [illegible] recovered some strength It was called the child that died & returned to life again The above is account of the disease as it most commonly appears. It is different however in different years sometimes effecting one part of the system sometimes another A practitioner keeps this [illegible] [illegible] 60 Case of a female child 2 yrs of age. The disease ran the most rapid course I ever witnessed. The whole system became affected; the pulse was full & frequent, the skin hot & the tongue furred. In 24 hours the disease came to a crisis and exhausted the excitability of the system; the pulse grew faint, the skin cold and the respiration languid the patient became insensible & was apparently dying sinapisms were applied to the abdomen, ankles & wrists & heated bodies put into the bed, to restore warmth. After the sinapisms had been on an hour and excited some redness, epispastics were applied in their stead. Ammonia & ether were put into the mouth & caustic ammonia was applied to the nostrils to excite Inflammation so as to blister. Ether was also put into the mouth In about two hours the system was resuscitated. Immediately a train of most violent nervous symptoms followed the chill became convulsed almost instantly. After trying antispasmodics in vain the convulsions were checked by laudanum, 6 drops, every two hours. The laudanum lost its effect in two hours & needed to be repeated. The blister on the chest produced a deep ulcer which was difficult to cure Finally tonic solution was administered. The child recovered Child of Mrs “Moulth???] Child of N. Beers’s vide p. 208 diseases and consequently meets with no new disease For they do not make sudden transition as in botany plants he is guided by symptoms & by the operation of remedies Appendix to Mes. fever acute marasmus This disease sometimes appears in an acute form with great irritation Sometimes terminates in hectic Patient will run down very rapidly [illegible] appearances enlargement & [illegible] of mesenteric glands “Called” consumption of the bowels” or Marasmus” Mesenteric fever is thought to terminate in hectic Probably it does especially in scrofulous patient and in those bad cases where the tubercles with a mesentery ulcerate “The pain in the bowels is no usually very severe but of a continued aching kind generally better removed by [camomile] injections than by anodynes” 61 Mesenteric Fever Marasmus tabes [illegible] [illegible] This disease arises from obstructed glands in the mesentery & is accompanied with morbid secretions of the stomach & liver bowels. It is sometimes the consequence of some other fever. It is often connected with scrofula, & it is apt to be attributed to worms. The disease attacks children of from two to ten years of age. Symptoms. The fever is of the intermitting remitting kind, with irregular paroxysms attended with tumefaction of the abdomen, costiveness, indigestion, loss of appetite & very irregular appetite & with paroxysms of pain in the bowels. The patient complains much of its bowels, but the affection seems to be rather distress then sharp pain & is neither constant nor regular. The countenance is very pale except when the cheeks are flushed with fever & the limbs are emaciated This is generally a chronic disease, but sometimes it is acute, & exhibits strong marks of irritation in the system. It may terminate in hectic. Dissections exhibit an enlargement of the mesenteric glands. Causes. It is sometimes as has been said above, the effect of another fever. Among the poor, with whom it is most frequent, it is caused by coarse and unwholesome diet. Children born of scrofulous or gouty parents are more subject to it & hard labor by the mother during the period of gestation may have some influence in predisposing to causing this disease in the child. Patients in this disease are subject to paroxysms of pain 62 The indications are 1st to empty the bowels and to keep up a gentle peristaltic motion in them 2nd to change the secretion of the chylopoeitic viscera. 3d to remove paroxysms of pain 4th to remove the obstruction in the lymphatics. 5th to impose the digestion & to invigorate the system generally 1at To move the bowels and keep up a gentle peristaltic motion mild mercurials as blue pill or calomel & chalk should be given & at the [illegible] time friction as in almost all chronic [illegible] complaint should be employed, upon the abdomen, and persevered in by the attendants. A very good mercurial preparation, will be a pill of four parts gr. blue mass and one 1 or ½ gr of ipecac adding a little opium ½ or 1/8 gr of the bowels are very irritable. If this preparation is not sufficient calomel may be substituted in a dose of 4 to 6 grains. The tincture of rhubarb has in some cases answered well as a laxative & corrector combined with neutral salts and aromatics 2nd For changing the secretions, we must rely upon the articles just mentioned, and also upon those to be mentioned under the 4th head 3d For alleviating sudden paroxysms of pain injections of a gill or a half pint of camomile tea have been found serviceable. If these fail give a camphor injection The pain is relieved by opium plaister There is but a small quantity of iodine and [illegible] effect appears to be produced than shd result from the small quantity of iodine Neutral salts in connexion with tonics have undoubtedly [illegible] deobstruent powers 63 4th For removing obstructions of the mesenteric fluids burnt sponge has been thought very efficacious. I formerly questioned whether it had any superiority over soda. Now it is supposed that all the virtues of the article are owing to the iodine continued in it. It would probably be [illegible] better better to give tincture of iodine in doses of 2 or 3 drops. Still the burnt sponge containing carbon & alkaline matters may have peculiar properties The neutral salts given with tonics have some influence in removing these obstruction It has been proposed to use mercury by injection for this purpose. I know not that it has ever been tried For the indication I have been in the habit of employing the muriate of lime & here given it in connexion with the mercurial pills mentioned under the first head It may be made by adding muriatic acid to chalk or marble & the dose for a child of 3 or 4 years, should be from 5 to 50 drops, given in tea coffee or milk. It is best to begin with a small quantity, say 3 drops & increase by one drop at every dose until the stomach is offended remembering that the stomach bears the article best if much diluted. The muriate of barytes might be used; also the carbonate of barytes is used in dose of but 2 or 3 grains, it being a powerful article. But iodine is probably the best article that we know of Other articles containing iodine, have been used besides burnt sponge, as [fucus] [nodasus] & vesiculosus [reckoned] vide scrofula mur. [illegible] dose 4 or 5 drops in milk & water for a child of 3 or 4 years increasing to 50 even 100 perhaps This [illegible] is not to [illegible] [illegible] it iodine as to be substituted by the latter We are apt to neglect an old remedy as a new one comes on The tepid bath shd not be used when the system is too much debilitated It excites the action of the mucous membrane and of the skin not affecting particularly the blood vessel add a little spirit to make the opium [illegible] if necessary 64 Muriate of lime has the important advantage of exciting the action of the skin which is generally torpid. Hence also the tepid bath has been used with success in this disease The flesh brush too if thoroughly applied several times a day will have a powerful effect. 5. To improve the digestion and invigorate the general system Carbonic acid is a most grateful stimulant to the stomachs of patients in this disease. Hence soda water and other effervescing mixtures, may be recommended spruce bar also & similar articles, if they agree well with the stomach. Aromatics as ginger & spice may often be added to them with advantage Among the tonics which are used to invigorate the system. Iron is very often employed & frequently with good success. The mildest preparations least irritating are the best, such as the tincture of the muriate, the martial flowers & the alkaline solution. Still iron is apt to cause irritation Cold bathing is a good remedy for invigorating the system but if the patient is much debilitated, a cordial should be administered previous to using it When the patient is much debilitated I have found anodyne plaisters upon the abdomen give great relief (where opium did not agree) I have used Noel’s plaister (similar to dyachylon) with soap mix opium zii with zfs of this plaister & spread it sufficiently large to dover the whole abdomen Children are very fond of potatoes but they should not be allowed, unless cooked so as to be dry and [illegible] and then thoroughly mashed Some vegetables as spinach, [illegible] & asparagus may be allowed but only in moderate qualities Preparations of meal of [illegible], especially fried, are bad Rx dough roll it in flour and then cut into thin slips, twist & bake them for [some] hours An excellent preparation for dyspeptic batter than crackers called twisted bread In making broth avoid adding rice, flour, etc. which will make the compound approach the nature of pastry and be more indigestible. Make broths as simple as possible & season with pepper & salt 65 Under this head may be ranked the use of the terebinthinates which have a valuable effect upon the mucous membrane of the alimentary canal The best article is a decoction of white pine bark, which is milder than any preparation of the turpentine of the shops Regimen. Flannel should be constantly worn next the skin to keep up an action in it. The patient should take exercise in the open air whenever the weather is good & damp easterly winds should be carefully voided as they have great influence in all chronic affections particularly glandular of the bowels. Friction & cold bathing have been already mentioned. Diet. This should be carefully attended to Raw fruits, potatoes and other garden vegetables, corned beef & in short all articles which are not of the easiest digestion or which have any tendency to ferment & become acescent in the stomach should be forbidden & caution should be enjoined that the stomach be not distended with liquids, so as to interrupt digestion. The diet should be dry consisting of toasted bread & farinaceous vegetable substance, as arrow root etc. well boiled & seasoned with a little wine & spice. If meat be given it should be broiled & eaten, with condiments. In some cases a piece of lean beef that has been partly broiled & then boiled, makes a broth that is grateful & sits well on the stomach. But if there is much dyspepsia, broth of any kind a not good If this fever terminates in hectic the mineral acid shd be used Undoubtedly however the affection may be produced by excessive purging vide next page low states of fever in adults also for the state of the bowels occurs much oftener than some phys. are aware of “The gases may arise from the ingestion, from a fermentation of the natural secretions, or, as I think from a direct secretion of gas by the intestines. this alone would see to account for the rapidity of its production” sometimes small watery stools 66 Tympanitis In diarrhoea dysentery & constipation with fever & typhus fever after these diseases have passed the first stage, the bowels of children affected with them, are liable to be affected with tympanitis. a troublesome symptom This state of the bowels may occur of itself about the time the febrile action begins to subside, or it may be brought on at an early period by the use of astringents, or by heat produced, either by too many bed clothes or by hot articles applied to the body for the purpose of exciting perspiration it is important to examine daily the state of the abdomen in children affected with bowel complaints, that a tympanitic state may be obviated, as soon as it begins to appear The abdomen is [swollen] and elastic to the touch feeling tense like a drum head under the fingers We can tell as soon as the hand is applied whether the swelling proceeds from inflammation, or from imprisoned air, for in the former case the pressure will cause pain The proximate cause of this state of the bowels I believe always to be a relaxation of the villous coat of the intestines & a deficiency of peristaltic motion in consequence of both which the villous coat falls down & forms a valve which confines the gas, while at the same time there is a morbid secretion of all the chylopoeitic viscera which [illegible] the evolution of the gas In the first stages of tympanitis, the alvine discharge usually cease even if there had been diarrhea & dysentery before & the little patients exhibit signs constant [illegible] not acute pain of great uneasiness from the unusual distention of the “It is thought by some that tympanitis is always occasioned by bad treatment in not giving cathartics enough at the common [illegible] Such persons probably do not examine the abdomen of their patients with sequels of severe bowel complaints. Tympanitis comes on whether cathartics have been used or not and nothing is more likely to bring it on than an excessive of cathartics at the commencement of the disease” The temperature had been raised above it secreting [illegible] & the child might have died “I am very partial to diaphoretic measures in general but must confess it is often abused If carried to excess it rapidly exhausts the patient also if excessive heat as aplied and the pat. does not sweat.” 67 bowels. In the progress of the disease tympanitis the child frequently comatose. The tympany is not always to be regarded as a dangerous symptom it sometimes indicates a favorable crisis, yet if it is accompanied with coma, there is danger that the brain may become seriously affected. If symptoms of congestion in the thorax exist, the disease of the thorax should claim our first attention, and the tympanitic state of the bowels be treated as a [illegible] complaint Treatment. The indications are to evacuate the flatus and excite healthy action of the viscera of the abdomen If the disease has been produced or aggravated by heating applications too many bed clothes or too confined an atmosphere, the heated substances should be removed, the bed clothes thrown off & air admitted freely to the patient. In the summer of 1814 I was called to a child sick with dysentery whose bowels became extremely inflated in consequence of filling with the steam of boiled potatoes in [illegible] the bed in which he lay The child because if much [illegible] & [illegible] was so difficult that it was thought to be dying; but upon removing the potatoes throwing off the bed clothes & opening the doors, the symptoms were at once amended & in the end the disease was completely removed by the use of a little [cajeput] oil in water and laxatives For removing the flatus of the bowels we may use enemata of the decoctions of aromatic plants or suds, such as catnip, camomile; the seed of fennel caraway or masterwort seeds or the essential oil of such suds may I prefer camphor to any other articles 3 or 4 [illegible] IN colicky complaints etc. I have known more benefit [illegible] injections of camphor in milk & water than from any [illegible] articles and that too after the most violent purgatives had vailed. I know of no article which operates so well in relieving irritation of the pelvic viscera [Anodyne] balsam Rx vol. [lin] zi [illegible] camph “Sometimes blister the abdomen” 68 be injected in milk and water. But I think I have experienced the greatest benefit in the case of children from the injection of a teaspoonful 2 or 3 of the tincture of asafoetida in a gill of warm water. It unites more readily with the water of a little milk is added A pipe of ivory or the pipe of a common injecting syringe may be introduced into the rectum as is recommended in hysteria, for the purpose of evacuating the flatus. I have sometimes used an elastic catheter with success The peristaltic motion of the intestines is to be excited and healthy secretions induced For this purpose we are to apply friction with dry flannel to the abdomen and mild cathartics are to be given. The latter may be jalap aloes rhubarb etc. with castor oil to work them off If frictions do not succeed, we may apply volatile liniment camphor, oil of origanum & finally epispastics We may likewise give internally cajeput oil in 3 or 4 in sugar oil of mint, oil of caraway, asafetida zfs to si etc. which is [illegible] to offer [illegible] its stomach & is not offensive to the taste and magnesia with [illegible] & cubebs [illegible] [illegible] or guaiacum Dr Good classifies [worms] according to their locality yet he makes mistakes as to their locality Much has been under the subject, and the remedies are almost innumerable. It is rather difficult to select the most important parts of the subject 69 Worms This subject naturally follows that of bowel complaints From testimony which cannot be invalidated it appears that worms of various sizes and forms have been found in almost every part of the human body. It is only in the alimentary canal however, that they occur with any frequency and give rise to symptoms, from which we are led to infer their presence Those worms which are of anomalous kinds, or are found in anomalous situations (oftenest perhaps in the lungs & frontal sinuses) as they are of rare occurrence & as the indications of their presence were either very obscure or altogether unknown wanting are interesting only as curiosities and will be passed over, without any notice, except an occasional reference to the fact known with regard to them “Worms in the alimentary canal are so common, as to have given rise to a class of diseases called verminous & a class of therapeutic agents called anthelmintics. The kinds of likewise of worms which occur in this part of the body have been thoroughly investigated & we are in possession of a large mass of information upon the subject I shall consider this subject under the following heads 1st The kinds of worms found in the al. canal 2nd their origin & that of worms in general, found in the body 3d the general effect they produce on the system & the general symp 5th the morbid effects produced by each species, with their treatment 4th the general treatment of verminous diseases 70 II. The genera of the common intestinal worms are three; toenia ascaris & tricephalus Of the tania there are two species. Tania solum or cucurbitana & t. lata or vulgaris. Of the ascaris there are also two specis of a. vermicularis & a. lumbricoides. 1st Tania This a long flat worm varying much in breadth and thickness which is formed by a chain of flat articulations, united by a border or edge. The accounts of the length of this worm are almost incredible from thirty to a hundred feet. Taenia solum (called also cucurbitina or gourd seed worm & the armed taenia) is distinguished by having the head forked and surrounded with papillae or long fangs (holders) by which it fastens itself to the mucous membrane. The broken off joints have when discharged the appearance of gourd seeds. hence its name of gourd seed worm. Taenia bata (or vulgaris the unarmed taenia) has an external form like a ribbon joints scarcely perceptible & is white and seen transparent. The head is narrower & smaller & the papillae not elongated 2nd Ascaris vermicularis & a lumbricoides The first, a. vermicularis (thread worm, pin worm & when existing in number called ascarides) is filiform, slender at both ends & from half an inch to an inch in length & of the diameter of a small thread found generally in the rectum & though not confined to that part of the intestines. It feeds on the mucus of the intestines & produce its young in immense quantities. It is found in the stomach & called maw worm 71 Ascaris lumbricoides (or [illegible] long round worm) is perfectly round & from four to ten inches in length bearing a striking resemblance to the common earth worm It is said sometimes to perforate the intestine with its mouth 3 The trichocephalus now called [tric???] is a small capillary worm from an inch to an inch & a half or two inches in length. The body is about half an inch in length & Is terminated a tail which is twice as long & end in a fine hair-like point In addition to these worms have been reckoned two others the vesicularis & the gordius. The former is a small vesicle found in the brain (sometimes in great numbers) & containing many small worms. It is now considered a hydatid & is excluded from the subject of worms & verminous diseases The gordius (horse hair worm) is found in soft stagnant waters from four to six inches long & twisted into various knots & contortions” Good. They are sometimes found in the earth in great numbers they turn black on exposure to the air & resemble horsehair, hence their name of horsehair worm They are very common in our vicinity They are rarely found in the human stomach. I have known them coughed up in abundance from the lungs; when they had probably come from an abscess in the liver. It gives rise to a severe disease among the [lapladens]. Vide Good. The maggots of the common house fly & the’ larvae of many other insects, have occasionally been met with in the alimentary canal of the human body vide Good What were formerly called vesicular worms are now considered as hydatids. [Brera] or worms recommended An attempt has lately been made to revive the doctrine of [equivocan] generation. The learned advocate has attempted to fortify his opinion by the analogy of vegetables. But where the experiment has been made the seeds of the forest trees that come up as [illegible] may be found at the roots of the young trees Hyoscyamus formerly was common here but is not now However when the gourd is broken in the college yard Hyoscyamus springs up. It has also in the soil brought from a cellar in Chapel St. Leeches & a variety of insect are undoubtedly taken in in water etc. In Duncans [illegible] we shall find an account of a number of caterpillars [illegible] by a child produced by eating cabbage leaves I think I have never known an instance of worms in children while nursing 72 II II. The origin of worms in the human body Worms arise from eggs. Some multiply by depositing their eggs to be afterwards fecundated by the male. Others are propagated by copulation between the two sexes While a third kind of the taenia fecundate themselves. I have spent much time in investigating the origin of worms in the human body but must confess that I cannot satisfy myself upon the subject. It has been supposed that worms found in the human body are produced from eggs deposited by flies about the rectum, at the time of going to stool. Were this the fact, they ought to be more abundant in summer than in winter, while the reverse is the fact. I am inclined to think that the rudiments of worms are contained in certain kinds of food as apples pears, cider water & unboiled fruits and vegetables. In infer this from the fact that worms make their appearance, oftenest when such articles have been taken & disappear when they are avoided. If confirmation of this view of their origin we find that children are rarely if ever affected by then when under three months of age & seldom while they are nourished from the breast. For though some have asserted that they have seen worms in the bowels of children within the mouth & even before birth yet the fact is not well ascertained. Breras opinions, also adopted by Good speaking of the fluke worm There is no doubt of the fact of worms within [fetus in uteri] 73 Brera thinks that the minute eggs of worms are absorbed into the circulation He says “when we consider that the eggs of worms are so small that they are not perceptible by the microscope of Hoffman and these eggs themselves are masses of small eggs, nothing is more probable than that the eggs of worms are absorbed by the lymphatic vessels, pass in to the circulation pervade the system with the blood & are deposited in the various parts of the body, where they enlarge and unfold themselves when circumstances favour their development.” If worms are found in the foetus, the fact will favour this idea that the eggs of worms are carried into the circulation. It may be remarked also that the parts of the body which favour the development of their eggs are those abounding with mucous The hypothesis of equivocal generation is neither specious nor probable. It derives no support from analogy aid from reason, nor countenance from fact In its operation it is worse than useless as it tends to obscure truth by substituting conjecture while it disregards with the most vague and licentious imagination the boundaries between the animal and numeral kingdom & ascribes to chemistry what pertains only to animal life When the creator first gave being to the natural world, every part of the vegetable and animal system was brought into existence by an extraordinary exertion of productive power. They were not moulded by the slow operation of time & the cooperation 74 of mechanical and physical forces, but he spake and it was done. But since that first act of creative power, we find are that these creatures are propagated and perfected by processes more gradual successive and [operose], many of which may be traced by human wisdom and admit of being regulated and controlled by human culture & ability Rosenstein says “from the eggs of a fly proceeds a fly, from the egg of a hen a pullet and not a serpent, from the egg of a goose, a goose and not a fish So from one worm is produced a worm and nothing else” II II II. The effects of the presence of worms in the body When the seed of worms are once developed in the human body, the health is more or less affected, and the morbid symptoms which then appear are in proportion to the number of size of the worms the sensibility of the part they occupy and the general morbid diathese which takes place at the time, whether the cause or the effect of the worms Worms in the alimentary canal are less frequently the original cause of diseases than is generally supposed, inasmuch as in many cases of disease where they exist, the disease was merely aggravated & not originated by the worms & all the symptoms of worms from which it is common to infer their presence, may be occasioned by 75 undigestible substances for a diseased state of the bowels Worms are often also found to have existed & that too in great numbers, where the general health has been apparently good. I well recollect the case of a child in North Milford who fell from a height & was taken up in a state of coma from the concussion. A dose of calomel was given him which brought away twenty or thirty large worms. The child had been healthy to all appearance previous to the accident. Some physicians go so far as to say that worms are necessary for the health of vigorous children that they are nature’s scavengers a natural provision to destroy the superabundance of food taken into the stomach. Dr Rush was of this opinion. The opinion supported by Dr [Parr] It is a fact beyond controversy that very healthy children have worms with out manifesting any symptoms of their presence until the supervention of some other disease causes them to make disturbance in the system. It is but seldom that they are the excit. cause of dis. The following are some of the ways in which worms are injurious to the system. They may be injurious from their number obstructing the bowels and consuming too much food. They are particularly hurtful by the irritation which they produce when the irritability of the bowels is excited by fever. They sometimes threaten suffocation by rising in the oesophagus & in one instance a single worm I have known to lie in the fold of a volvulus of the intestines so as completely to obstruct the passage 76 Linneus attributed the dysentery to a worm or insect [illegible] dysenterical [languis] the measles to a similar origin. Various authors the itch, sigler, petechiae lusitanus the syphilis martin the elephantiasis nyander, eruptive & contagious diseases in general lancissi, plague, remitting & intermitting fever considering miasm [it] being a collection of insects # some authors, toothache Dr [Adam] observes cancer itself is nothing more than an animalcule a worm or an insect. It would seem from such speculations, that a great part of the diseases which flesh is [illegible] to result from a superabundance of vitality and that as Good remarks in his [illegible] corruption is no longer the triumph of death over life, but of life in one form over life in another. Such fancies lead into the wildest speculations of equivocal generation & relinquish all principles & all limits in natural history. # Vide N.Y. Rep. about the year 1815 77 Symptoms of worms. Those children are most frequently troubled with worms whose powers of digestion are weak. The symptoms of the presence of worms in the alimentary canal are very equivocal, for they may all proceed from other causes. They are countenance pale or flushed sad and dejected livid around the eyes, eyes sunken eyelids swelled pupils dilated itchings in the nostrils, head ache after taking food, mouth water [illegible] filled with saliva, breath fetid, great thirst, grinding of the teeth in sleep, starting in sleep fainting vertigo, palpitation of the heart, irregular pulse & cold abdomen bowels flatulent costive or loose colic throbbing in the bowels severe from [illegible] the small [intestines & umbilicus] appetite irregular & craving loss of appetite pain in the stomach when empty, which is relieved by food urine increased or diminished turbid and milky, stools irregular, containing much mucus nausea & vomiting Sleepiness particularly after eating, bloated countenance swelled nose & upper lip, paleness of the lips, irritation about the mouth, rubbing the nose, itching at the anus irritation about the neck of the bladder dry & convulsive cough difficult respiration sense of suffocation paroxysms of suffocation body emaciated frequent flushings of fever with irregular pulse convulsions, epilepsy and partial palsy. Of course these are not all present at any one time Chorea catalepsy & epilepsy are produced sometimes, by worms Dry convulsive cough Diff respiration In addition to the other symptoms there may be these of irritation of the lungs producing cough also irritation of the brain [772] It will be impossible to class all the articles inasmuch as we do not certainly know the modus operandi of many articles which yet have sustained their reputation for [illegible] Much stress has been laid upon the operation of cathartics in evacuating the [illegible] which the worms generate by their irritation, just as irritation in the lungs produces [illegible]. But then the [mucus] although it forms [illegible] for them, an effect more than a cause, and the worms will make [mucus] enough for themselves Probably many caths act by their acrimony upon the worms themselves. Others by the violence of their operation dislodges them. “Aloes are beneficial in mild cases as a tonic when there is no excessive irritation. If there is excessive sensibility & irritability they are improper as they irritate the rectum they may be given by injection When there are symptoms of worms though no worms exist aloes are serviceable in the form of elxiir prop.” 77:a. IV. [general treatment] In the treatment of patients afflicted with worms two general objects seem to have been pursued both in popular practice & in that of physicians 1st to destroy & expel the worms themselves & 2d to obviate their effects upon the system & at the same time by the improvement of the general health of the patient, prevent their recurrence and increase This second indication will often coincide with the first, inasmuch as a diseased state of the body is the most favorable for the multiplation of worms Of those remedies which destroy or expel the worms themselves we have three kinds 1st those that expel them by strong cathartic operation 2nd those that act mechanically upon them 3d those that are prisoners to them. 1st Although strong & even violent purges may be used to drive out an accumulation of worms in the bowels yet they should not be often repeated as they would increase the weakness & irritability of the stomach & bowels to such a degree as to favour this increase. In general calomel will be the best cathartic inasmuch as it will tend to promote a flow of healthy bile & to restore healthy secretions. In Europe the gall of animals has been administered. One of the best forms for the administration of cathartics is that of alkoholic tincture, for the sake of the joint effect of the alcohol hence elixir proprietalis in teaspoonful doses & the tinct. “The bark of the button wood taken from the north side of the tree has been recommended. It is a nauseous bitter & a cathartic good” # “It is a question whether cowhage acts mechanically or whether it contains an acrid principle like that which exists in the nettle” # One of the remedies that I have most reliance on for ascaride in tinct [illegible]. Fill a bottle with the young inner bark fill the interstices with [prosp] spirit & give I to zfs night & morning It is an old remedy and better than tinct aloes It is tonic & deobstruent” Some of the acids to be narcotic, are more probably active merely by their pungency, odour etc. 77:b. of hickory bark or buds have been found very serviceable Podophyllum peltatum is much used but is probably not better than other cathartics. The best form would be that of a tincture 2 Mechanical remedies are not now used. Cut hair has been given cowhage though some doubt whether the operation of this is wholly mechanical. I have thought that the root of osmunda given in pieces acted mechanically The filings of tin, formerly were much employed as was also an amalgam of tin & mercury. There is a curious account in one of our journals of a man in Kentucky who took a pound of the amalgam & was unable to expel it from the bowels The mass lodged in a part of the intestines & could be felt externally It was very troublesome to him when riding. Oil has been given with the intent that it should fill the respiratory pores of the tape worms & thereby destroy its life. In Madame Nouffeurs recipe The supper of panada is intended to act mechanically by its bulk. 3d The remedies which destroy the worms seem generally to be narcotics All articles of this class however do not have this effect opium for instance. Particular animals are sensible only to particular narcotics as for instance swine are poisoned by stromonium while sheep eat it with impunity. The most valuable article of this class are the two species of spigelia s. [ma??ndica] & s. anthelmia A strange notion has existed about a little innocent [illegible] was considered as the narcotic agent Similar reasoning has been used with respect to denarcotising the opium Opium denarcotised would be not better than bread Spigelia zii in ¼ pt water to a child may be given in divided doses. It is better to give a cath. e.g. cal. or ruhb Spegelia from zfs to zf for an adult Sometimes but rarely it operates itself as a cathartic Sometimes convulsions are produced Our pink is bad because it is gathered by [illegible] packed in hogsheads & the rotten saved & the rest [illegible] The emigrants from St. [Illegible] brought what they called worm syrup which they said shd be given in the night because it affected the eyes S. [anth.] is [illegible] S. [illegible] about zi if S. anth. “Pink is given more especially for the [round worm] & sometimes for the tape worm” [illegible] [illegible] & [areca] [oleacea] zii to zfs “The French use the syrup of peach flowers & seeds They first give sulph either zi in [illegible] decoction male form & an injection of the same. They probably act by their prussic acid” 77:c. The former is the one commonly used in this country and in England It is called Carolina Pink. This is a most valuable article and is useful not only for its operation upon the worms but for its effects upon the system, in allaying the irritation which they occasion. I have prescribed it for a cough & other symptoms of irritation where I had no reason to suspect the existence of worms Then given for its effect upon the worm from half an ounce to two ounces should be given in decoction in the course of the night, accompanied with rhubarb or some other cathartic to drive the worm off while in a state of intoxication. It may be given in powder in a dose of from 10 to 20 grs The French W. Indies s. anthelmia is used & called wormgrass. It is a stronger article than ours The French use the article in form of a syrup & give a teaspoonful at a dose. Veratrum subadilla & helleborus [fetidis] belong to this class and have been given in doses of 2 to 6 grs for children In Europe the most famous article of this description has been the Felix mas Other articles of this class are camphor, prussic acid & tobacco The bark of the cabbage tree (of which there are two species vide Good) is found highly valuable in this way by the West India physicians Other articles which have been said to be successful in cases of worms owe their success apparently to their acrimony in whole or in part, such as the terebinthinate oils Oil of turpentine is the one commonly Various aromatics have been used, as chenopodium [illegible], rue tansy “The leaves of cedar juniper & [illegible] powdered 20 grs They are acrid stimulating and tonic & may have a mechanical action. It might be used to add to the powdered leaves some aromatic as rue ol. tansy [worm] wood etc.” “Melia [azidurach] bark of root or plant zfi to zi act as emetic cathartic & narcotic. Acts more effectually at the south where the recent article is used” 77:d. employed should be given in large doses, when it will prove cathartic. A concentrated solution of salt has been strongly recommended given by the mouth or by injection Ether is much used by the French & perhaps has an effect upon the worms. Some of the other antispasmodics which have been popular may also have some effect upon them such as asafoetida, petroleum the essential oil of the chenopodium etc. Perhaps arsenic poison intestinal worms I have known it cure. Ammonia may perhaps act on them 2 Of the remedies which are designed to have an effect upon the system. In severe affections from worms our first attention must often be directed toward quieting the excessive irritation of the system, by antispasmodics. Various popular remedies for worms seem to have little other virtue The chenopodium anthelminticus & c. ambrosioides called worm seed & the c. botrys. or [juris] oak ar probably valuable, mainly if not entirely a nervine. They may be given in decoction or the essential oil may be used. The garlics are used in syrup or decoction they are nervine 7 have considerable effect as condiments upon the intestinal canal. The ictodes fetidus is of this class & so are the empyreumatic oils, petroleum given in a dose of 10 to 40 drops barbadoes tar etc. For giving tone to the digestive organs and exciting their sluggish action the tonics the bitters & the aromatics are indicated while mercurial [Artemesia] ][santonica] is no better probably than the other bitter tonics Some confusion results from the appellation worm seed being applied both to this and to [illegible] botrys c. anthel. & “Indeed anything which tends to [procure] healthy secretions of the viscera. Of this kind are the mercurial which produce healthy bile which is especially [illegible] to [illegible]” # “Indian corn or maize has been supposed to favour the generation of worms in the body. The aborigines of this country have been peculiarly subject to them perhaps from this cause” Worms are far less common now as are also colic dysentery et. than formerly when cold water & cider were drunk instead of tea and coffee AT the south likewise the negroes who feed more upon crude and raw articles are more subject [illegible] of the plantations it is a rule to give a decoction of melia to the black children once in 3 months # Though you can cure worms generally by calomel yet sometimes they will resist all treatment Eupatrium perfoliatum is used for worms Flowers of [zinc] are antispasmodic so also sulph zinc Dr Rush thought well of [sugar] especially when given in the morning Petroleum seems to be a valuable article a substitute for turpentine It may be supposed dangerous, but I have used it for many years without inconvenience I began with small quantities from fear of danger, but now I give 10 30 or 60 grs It very often to produce no violent effects. Yet we must not conclude hence that it is useless. Asafoetidae for instance produces nothing but a little [illegible] in healthy persons 77:e. preparations & other deobstruents will be valuable adjuvants. The metallic tonics as the preparations of iron & of zinc, the mineral acids, myrrh, bark, the various bitters & the astringents have been found useful I have used alum whey with advantage. Among us the geraniums & all the indigenous aromatics & bitters have been given in popular practice. Alcohol from its stimulating effect upon the digestive organs will be a useful vehicle, for the exhibition of medicines. Condiments used freely with the food, will answer to the same indication The diet of patient troubled with worms should be dry & stimulating, rather than liquid & cold raw fruit, acids cold water & all indigestible articles should be avoided & in extreme cases I would advise that neither food nor drink be taken but which has not been subjected to heat. I have apparently cured patients by this means. “[illegible] toasted bread [illegible] [illegible] vegetable [illegible] though they occasion [illegible] dyspepsia” A multitude of heterogeneous articles have been used as anthelmentics, besides those already mentioned; some of them are sugar; worm-wood; rue; peach flowers; bark’ of prunus virg; valeriana selequa used by the French; muriate of barytes; injections of mur. of tin (Alibert); oxide of tin grs iii with etr. of juniper (Alibert) mur. of amm. of linseed; mur. of amm. [illegible]I with jal. or rhub 10 gr.; all the forms of ammonia; crude mercury; merc. boiled in water; aethiops mineral; artemisia [illegible] [illegible] ([illegible] [illegible]) & a. [illegible] [illegible] [s?tonica] worm seed bitter & of some value; melia azedarach much used at the south; butternut bark intensely bitter dose a tablesp. full of decoct cathartic & said to be narcotic; allows asclepiadis I think I have seen the a. [illegible] then beneficial; etc. etc. Garlics seem to do well how it is difficult to say perhaps operate upon the worms. Garlic also will relieve the eruptions of worms. It is though also that garlic prevents worms I have a very good opinion of sulph ether introduced into the rectum used by the Germans, Italians nervine & antirritant. It is valuable both in cases for worms & in those of irritation & affections of liver severe pain in bowels etc.” ½ oz or 1 oz. iron filings taste by [illegible] remedy worse than disease Wherever leaves of [illegible] are recommended you may give our common juniper For the imported [illegible] loses its strength by keeping & drying Rosenstein recommends cold water during the operation of a cathartic He recommends effervescing mixtures to destroy the worms by carb. acid An old remedy of the tonic kind is alum whey Rx milk & water equal quantities & put in [illegible] [alum] to [illegible] give the whey [illegible] children takes it pretty freely; It is a given in cases of relaxation of bowels and for ascarides & round worm It is of consequence often to have a remedy [illegible] and not require to be forced down 77:f. Various external applications have been prescribed Oxgall & venice soap aa zi made into a liniment with oil of tansy or wormwood; Aloetic plaisters; ether oz vi, bruised garlic zi, camphor zi (used by the German Brera) for a liniment; petroleum mixed with gall; Most of the patent medicines for worms [illegible] or both contain calomel, Storr’s lozenges are calomel with sugar & gum. These are his white lozenges. His brown are resin of jalap, gum tragacanth & calomel. Good on the authority of the Germans recommends [illegible] milk Electricity A popular article (cath.?) is decoction of [plantanus] occidentalis strong bitter For ascarides I rely as much as any thing upon a saturated tincture of the juglans [illegible] & [illegible] All the indigenous bitters as cherry bark [illegible] melia [azedarach] zii of recent root is divided doses ½ pt water. When dried & long kept it is apt to disappoint here. It is acrid [as the] narcotic & cathartic a powerful article The berries are also narcotic causing lard to fall down not from [choking] as has been thought The [planters] think it too powerful for [white] children! Tape worms frequently produce headache [illegible] about the umbilicus yet generally produce a sense of weight. Yet I have known persons evacuate them when they had not been suspected Case of a man who had kept taking remedies for a catarrh Finally a medicine ? brought away to his own surprise and that of his physician a tapeworm Perhaps vomiting occurs oftener from tape worm than from any other species # “When the worms are very numerous, there is a sensation of something falling from side to side on a change of posture” 78 V. Symptoms of each of the kinds of worms with the treatment. 1st taenia solum. This worm generally inhabits the upper part of the intestines & adheres so firmly as to be removed with difficulty It is sometimes solitary but commonly in considerable numbers. When brought away from the bowels many of the joints are separate & have the appearance of gourd seeds hence the name. 2 T. lata or vulgaris This likewise inhabits the upper part of the intestines and is usually in families of three or four Both are called by the common name of tapeworm They may exist without any apparent symptoms of worms or they may give rise to the severest affections In general they are attended by severer pain in the bowels & more violent symptoms in general than the other worms. The diagnostic marks of their presence in great quantities, are sense of weight in the abdomen, # irritation of the stomach nausea & vomiting loss of appetite, irregular appetite weakness of the chylopoietic viscera, bloated countenance emaciation of the body etc. All these symptoms however may arise from mere irritation of the stomach of a child Adults are more generally affected with tape worms but children sometimes have them. For the taeina solum t. lata or vulgaris or cucurbitina the gourd seed worm the spirits of turpentine has been very successful. Though not prescribed by the physicians it has been used as a popular remedy here for more than T. lata fifty years. I have known a man of intemperate habits No cautions are given about the use of the article (so far as I know) But if it does not act as a cathartic immediately, it will produce great irritation especially of the urinary organs I recollect the case of a lady who had been treated with aph turp. in N.Y. taking 2 or 3 ounces Violent vomiting & catharsis had been produced and the tone of the stomach and bowels seemed to have been permanently destroyed Worry had indeed been brough away, but then they would come away themselves & the relieve was fallacious In delicate cases it had better be combined with castor or sweet oil In the case of the lady cath seemed to do no good, they would indeed bring away large quantities but they would return in a few days. I put her upon arsenic but she left town and I have not heard from her It is difficult to tell how arsenic operates whether upon the worms or producing healthy bile For the t. lata the spts turp. seems to do better 79 take a wine glass full of spirits of turpentine to expell a tape worm Though an habitual inebriate, he said he never had been so drunk in his life & large tape worm of this kind? came away # It is said sometimes to intoxicate & sometimes to produce irritation T. solum 2d The t. lata is the most difficult of all worms to manage. Spts of turpentine do no good at least in those cases in which I have tried the article In T. solum one case I gave zfs. In another I gave it in teaspoonful doses. In the latter it operates freely as a cathartic a single teaspoonful procuring as many as ten stools Worms were evacuated but they would make their appearance again in as large quantities as before. Indeed any medicine may bring them away for the bowels are sometimes so filled with them that they come away T. solum when the patient is walking, or is asleep. I have known two quarts to be brought away in a day, & then a fresh supply in a few days after! T. solum # Arsenic has succeeded better for this kind? with me than any other remedy, which I have used. In the case of a child 5 or 6 years of age who had both the round & the gourd seed worm the common cathartics were given with some advantage, as some worms were brought away; but the symptoms still continued and the worms passed occasionally with the stools. Fowler’s solution of arsenic was administered in doses of four drops three times a day. In a few days worms ceased to be evacuated the symptoms disappeared & the child has once had no recurrence of the worms [Osmunda] cinnamonea is bitter, subastringent and perhaps deobstruent. So is polypodium vulgare and perhaps more decidedly so The polypodium vulgare & felix mas They are used in chronic affections of the stomach & bowels & thought they have not obtained much reputation for worry in this country yet they have sustained their reputation for 2000 years. It was used by Galen “The [form] is tonic” 80 I recollect case of one patient, a woman, who kept passing tapeworms, in great quantities, for months. After failing with medicines I threw them all aside & tried diet All the food taken was roasted or boiled even the water used for drink was boiled. She was cured. It must be remembered the healthy bile & gastric fluid will destroy those worms & from this fact results an important indication, which I shall presently dwell upon. Felix mas the male form has been considered in Europe, as a specific for this worm. With us the osmunda cinnamonea [illegible] ([hog brake]) has been used as a substitute for it. It is bitter, astringent & sweet. The polypodium vulgare, which is tonic & deobstruent, & other forms may probably be used also The famous fern remedy bought by the king of France of Madame [Nouffleur] is as follows. Take a super of the following panada Rx water lbi [illegible] fresh butter z 2 or 3 bread cut into small pieces zii add salt zi & boil thoroughly. If the patient is costive give an injection of water lb is in the evening olive oil zii salt gr. s. The next morning eight or nine hours after the supper the specific is to be given viz. Felix mas ziii in powder, mixed with 4 to 6 z of the distilled water of the fern or the flowers of the linden tree the whole to be swallowed at a dose. In children the dose is reduced to zi of the fern Two hours after the fern is taken the patient is to swallow the following bolus R. cal. & scamm. aa grs xii Gamboge grs V powdered fine & made into a bolus to be given at one dose to a person of vigorous constitutiokn Ether acts especially upon the nervous system on which account it has been used as an anthelmintic Alibert for taenia gives about zi in a glass of the decoction of the male form in the [illegible] an hour after his doze zi of the ol. ricini are to be given in syrup or in composition the dose to be repeated twice & sometime three times a day The worm is usually evacuated after the first doses Mr [Bonadier] directs an injection of the decoction of the male form to which zii of ether are to be added Mat. Med. art. ether 81 Mathieu adds to Mad. Nouffleur’s remedy the filings of tine & the sulphate of potash The French & German add ether to the same remedy Rothier’s method is Rx powdered savin grs xx seeds of rue 15 cab. grs x oil of tansy gtts xii syrup of peach gr. s. make a bolus Take half in the morning & half after dinner, drinking with each dose a glass of vin. tincture of peach kernels Dr Baurdier gives the following Rx sulph. ether zi decoct felix mas 1 gill taken fasting 4 or 5 an injection of the same decoction with zfs of ether an hour after zii ol ricini or zi of the syrup of peach blossom the worm is discharged half organiz Oil is used in order to kill the tape worms by filling their respiratory foramina. Ol ricini has been given for taenia & other worms in doses of 3 or 4 z Liquid carb. amm. might be given for taenia The German physicians are fond of giving 3 or 4 ounces of castor oil They are fond likewise of peach flowers Within 5 or 6 years the bark of pomegranate has been recommended. Paris says bark of the root [illegible] probable however the office preparation is meant viz rind of the fruit which is the most astringent substance to the [illegible] which we have [illegible] also cathartic! I have not [illegible] N.B. The male form is astringent, and is given to enable the bowels by the tone it gives, to bear the [strong] cathartic afterwards. Hence the union of these give in [illegible] [illegible] may be useful I have seen the worm occasionally in rain water I recollection one man of 60 who informed me he had been troubled with then nearly all his life until he removed his [illegible] Change of place may effect a cure by change of water Probably [illegible] of our cholera are troubled with this worm delicate children only suffering much children troubled with them will be faint, have turns of colic etc. you will be called [illegible] Give an injection, and no worms will come [illegible] yet give afterwards a strong cath. & or repeat the injection and worms will come away proof that they were not in the rectum They probably breed in the duodenum I have known but one case in which they were vomited up. The subsequent cath. will bring away smaller worms More is done by diet int his worm than by any thing else Alcohol in this morning especially its bitter tinctures. Condiments are useful. Worms are less common now because condiments are more used. It is said that the aborigines when they cannot get salt used potash ashes by a condiment The aborigines are said to be very subject to worms # Ascarides sometimes produce severe pain at the umbilicus and colic # “Ascarides though often found in the rectum are generated in the stomach & small intestines. Hence they are sometimes no discharged till the second or third operation Hence they are sometimes thrown up by vomiting. I have examined this point carefully 82 3d Ascaris vermicularis. This worm is always troublesome when it exists in considerable numbers though it is but seldom that they exist in healthy persons in such numbers as to give rise to morbid symptoms. They are very common in children, and not rare in adults & are called by the generic name ascarides These worms are commonly found in the rectum & hence are often said to inhabit that part This is a mistake they multiply abundantly & lodge in the rectum as they daily pass void by sphincter. Sometimes they exist in the stomach in vast numbers (hence called maw worms) so as ever to threaten suffocation by rising in a ball into the esophagus & sometimes they cause severe griping pains by their presence in the small intestines # They pass in the stools & sometimes come away spontaneously at night, they are said even to make their way to the vagina & urethra of females producing troublesome symptoms X Ascarides are most troublesome in the latter part of the day & the first of the night, when they excite an intolerable itching at night [illegible] probably than feeding They give rise to symptoms of general irritation & sometimes to a cough # Ascarides are particularly injurious to dyspeptic patients & they themselves may give rise to the symptoms of severe dyspepsia such as craving appetite, indigestion, faintings. Flatulence, cold extremities pale & sallow countenance, cough etc. The irri “They are attended with violent itching about the rectum general irritation convulsions irregular appetite pale urine flatulence want of vigorous action of chylopoietic viscera increase of mucous secretion darting pains in the abdomen stomach & chest faintness cold extremities the symptoms of dyspepsia sporadic cough” Tobacco injections & tobacco smoke injected are very useful and will often cure. It is not safe for children I have seen great prostration produced in children & I have known an adult killed by a tobacco injection # A physician who had been much troubled with ascarides told me he had tried merc. oint. externally with advantage. “I have used it but was rather disappointed # When the ascarides are in the small intestines, tobacco smoke will do not good & by its debilitating effect will favour their existence “Injections of camphor and milk have done more to remove ascarides than all other remedies I have used. The injection immediately removes the irritation produced by the ascarides & the ascarides themselves. It may be made of milk ziv to spts camph. zi This is the form in which I have used it, probably an emulsion is as good, perhaps a better form” M. M. 83 which they cause sometimes, in children brings on convulsions Whenever, finally, they exist, in the alimentary canal they are accompanied with great quantities of mucus in this part. They feed on the mucus of the intestines, the flow of which they excite by punctuating the mucus membrane Treatment It is very difficult to cure a patient troubled with ascarides. The most immediate relief is given by injection. If the worms are in great quantities & too much “Tobacco smoke is one of the most powerful means we possess for the involved in mucus, they may be completely removed by cure of these troublesome worms” injecting tobacco smoke. Injections of warm water or milk & water will relieve for the time being by washing out the rectum & if a quantity of aloes zis to ½ pt is added a still better effect may be expected though camphor being a nervine & a poison to the worms would be a still better addition. Injections of milk and water, with camphor zii tinct camph to ½ pint, will if preserved [illegible] destroy them 15 grs of [illegible] [saladilla] have been injected. Still the frequent injection, required in bad cases may debilitate the bowels & consequently invite the return of the worms. For internal administration. I have found a tincture of the buds or bark of the hickory given in doses from a tea to a tablespoonful one of the best articles both for removing the worms & for preventing their return Drastic cathartics should not be depended upon for they weaken the bowels & increase their irritability & hence favour the production of the worms. On the contrary calomel & tonics should be given to restore healthy secretion Aloes if given should not be in large doses, for that will irritate the rectum still further, but in smaller ones as a tonic Oily articles shd be avoided as butter, because they relax the [illegible] of the intestines Potatoes, vegetables All kinds of pastry avoided All the metallic tonics are useful as tonics They are thought also to be unfriendly to the worms It is said that forth ascarides a pint or a quart of sea water has been drunk with advantage, producing vomiting & purging. Salt is a good remedy. Dr Rush proscribed a teaspoonful of salt in the morning to a gentler one much troubled with ascarides. He told him after trial than the remedy would not do. Dr Rush gave him, then, for worm powders # For the worm the [illegible] the pink shd be the remedy vide [illegible] “Rhub & cal. are the best cath. but all are useful For children Rx tinct. [illegible] Fowlers solut. cold water” “Common salt ground up with cochineal to colour & disguise the article. The gentleman reported that the last prescription had answered well. Dr Rush also believed in sugar. This more doubtful The asclepiasis have been much used especially for this worm especially A. incarnata called wild hemp It is dried pounded to a fine powder mixed with molasses & given in doses of a teaspoonful Or [illegible] down and make a strong decoction [illegible] the [illegible] with it molasses and give freely until it moves the bowels This much used by the practitioners of the state more than any other article after calomel. it is an article which may always be obtained growing in clayey situation and is safe The other asclepians are similar & may be used S syriaca is the most laxative 84 To prevent the return of ascarides, condiments should be freely used such as pepper, ginger etc. in short all warming and bitter things In extreme cases let the diet be so regulated that nothing shall be received into the stomach which as not been subjected to heat. Mercurial ointment has fasted in my hands. 4. Ascaris lumbricoides the long round worm is perhaps more commonly found in the alimentary canal than any other This worm more than any other is found to have existed in the stomach or intestines while the general health has been good is the presence of worms not suspected. Strong purges may be used to remove them & alcoholic tonic tinctures given to prevent their increasing. For this latter object the carbonic acid has been recommended in the London Med. & Phys. Journ. & in confirmation of the idea I have used soda water with advantage Melia azedorach or pride of India a decoction of the bark is much depended on at the south for their young negroes who are much subject to worms. It loses much of its virtue when dried. The spigelia is also sued but of this I shall speak under the head of general treatment. I recollect with an aff. of the liver wh often vomited up dark [gravous] blood, which had evidently been long in collecting. Finally he was said to have thrown at a snake. Many eyewitness testified to the snake & to its eyes & teeth. I saw it. It was a very large round worm of the kind To be distinguished only by the violence of the symptoms. The same itching at the arms will exist as of the ascarides, but non violent etc. “Treatment similar to that for ascarides. It is more common than is generally supposed. Many of disease & death by irritation from an unknown cause, are probably owing to this worm. In examination the contents of the bowels should be placed upon linen cloth and then this worm can be seen.” For the gordius Linnaeus recommended the angelica Archangelica (not our viz the [atropur????]) 85 5. The tricocephalus is but seldom met with The irritation produced it may be so great as even to bring on delirium & will be manifested by screaming throwing of the hands & [fat] etc. I have found this worm in a fold of the volvulus of the intestines vide Volvulus. I should try narcotics for this worm, but cannot speak from my own experience. I should recommend also an injection of a table spoonful of ether in a gill of water or mucilage. Ether given in this way will undoubtedly pass the valves of the intestines in a state of vapour Vesicular worms, according to the old division of verminous diseases, are met with commonly in the brains of adults & are attended with the symptoms of vertigo, convulsions apoplexy & hydrocephalus. Cases of worms & of colic are much less frequent with us than formerly; owing to the change in our mode o f living. They are said to be very common among the aborigines of this country One volvulus may be received within another a second, a third and fourth time & [illegible]. The whole may then become inflamed, the vessels may run from one to another, and the whole become one complete mass of organised matter or sometimes [illegible] “It may occur in any part of the intestines except the rectum though the colon is often received into the rectum” The symptoms of the two kinds [illegible] [illegible] owing to the different susceptibility of these two portions of the al. canal, and the diff. ages of the subjects of each Nor located in books vide Ed. med. & surg. J where the best account of it is given. Good merely mentions it as an accident that is found sometimes to have occurred in ileac passion “Predisposing of exciting causes” The cavity of the natural stricture may not be large than a goose quill, & such children will be very liable to an occurrence of volvulus This is not a primary disease. It occurs more in some families of [illegible] fibre & [illegible] phlegmatic temperament It may occur from debility of constitutional or that of the bowels [illegible] by bowel complaints etc. Local violence One instance, in here the child was apparently thrown into it by being carried over the shoulders 86 Volvulus or Introsusception This is a disease with which I was at first very much perplexed especially as I derived little satisfaction from the books Volvulus or introsusception is the reception of one portion of intestine within another. It doubtless exists often in a slight degree, when there is a strong action of the bowels & are inverted peristaltic motion & the bowels disengage themselves. Sometimes there is a double involution, or one involution within another. In some cases likewise the cavity of that portion of the intestine is entirely obliterated by the tumefaction of the coats. I have always found in post mortem examinations, that the upper portion of intestine was received into the lower & not vice versa the involution having been caused apparently by inverted peristaltic action This affection of the intestines occurs oftenest in children though adults are liable to it. It would seem also that some families of a leucophlegmatic temperament & delicate constitution are particularly liable. It may be caused by a natural stricture of a portion of the intestinal tube when it will be incurable It may arise from extreme irritability; local violence & injury may occasion it, & the irritation of worms may bring it on. Drastic cathartics may bring on volvulus & hence should be cautiously avoided where there is a liability to it. Bowel complaints, as colic, cholera, dysentery etc. sometimes terminate in one or more volvuli of the small intestines. The disease is more frequent in the summer, when debility is greater & bowel complaints prevail “Symptoms incessant irritation one or two copious evacuations but usually these have ceased entirely before the physician arrives constant efforts to vomit, resembling hicup constant efforts to pass stools & nothing passes but mucus streaked with blood Generally mistaken for hydrocephalus In bowels complaint of delicate children look out for volvulus It is much more common in some seasons than in others. About 10 years ago they were quite common. I had many letters from our students, who met with the disease & disagreed with the phys & gained [reputation]. They frequently sent me such accounts. Sometimes there will be a partial involution of the large intestines [illegible] to relaxation of inner membrane what descends like a funnel & may be felt by the finger # In the large intestines there is not very much irritation than is torpor of al. can. not much vomiting except upon the administration. There is no purging You may sometimes determine that of the large intestine by heaving the peristaltic action discard & stop at the [illegible] This is most common in adults. The symptoms are more mile # It occurs in females who have had long continued effetion of uterus, occurring in females about cessation of [catamen] and from long continued bowel complaints. The [inner] membrane will descend like a funnel An injection will perhaps 87 Symptoms These will be different according as the affection is of the small or of the large intestines 1st Where the small intestines have one or more volvuli the symptoms [illegible] vomiting or Symptoms like those of violent injury to abdomen vide case 1st 6.89 a constant endeavour to vomit as often as once in ten or fifteen minutes the matter thrown up being a greenish fluid or simply mucus. In severe cases the vomiting is attended with a discharge from the rectum at the same time. The stools are fecal at first & copious but afterward they are small in quantity & consist principally of white mucus streaked with blood the blood not being diffused throughout the mucus as “no fecal smell generally” in dysentery, but in streaks or specks. These symptoms are attended by others which indicate great inquietude or irritation such as throwing the h ands & feet, rolling the head paleness of coutenance This set of symptoms resemble those of hydrocephalus & hence volvulus is often mistaken for this disease. The pulse is small and frequent “[illegible] usually occurs in 24 or 36 hours” 2 A volvulus of the colon or rectum is not usually attended with much vomiting unless this is excited by cathartics. It is attended with the ordinary symptom of constipation. There is no evacuation from the bowels unless at times a little blood and mucus. If the passage be not completely closed, an enema thrown-up will remain & not come away if completely closed. it either cannot be thrown up or it returns immediately. Blood often follows the introduction of the pipe. Indeed the inflamed part is often so low as to be reached by the pipe & admit of being felt by the finger. come away immediately. [Schyl?la] of feces may come away And large quantities of mucus may come away sometimes ½ a pint. This is not apt to be fatal. Treat by a strong inject prescribe for the [illegible] with conium [illegible] etc. mechanical means The more cath. you give the more the unsolution is increased therefore give more Give mucilaginous injection, in involution of the small intestines, sufficient to fill the intestines. If it is said that the injection will not pass the valves. I answer that whether by sympathy or in whatever manner, I am satisfied of its utility # Give [illegible] enough to allay irritation I have treated # patients for 8 or 10 days without evacuation & cured them Not long since I had a case in what I suppose there was such a volvulus, for the attendants could not make the child receive injection. “thought the bowels were swelled” The child was suffered to get 8 or 10 days without evacuation & eventually died of another disease with which this was connected # In the incipient stages, filling the intestines with warm water [illegible] recovered. I was led to it from its [illegible] strang. hernia I am satisfied it acts well as a local nervine etc. I would recommend the injection of ether in cold water table sp. to a gill warm wat. will make it fly off. The inject of it is practised by the French & Germans. Other antispas. might be [injec??] is asaf. petroleum etc. 88 We may often hear a rumbling noise proceed as far as the stricture & then stop. Treatment The indications of cure are principally, to relieve the excessive irritation both constitutional & local & to attempt the restoration of the involved intestine chiefly by mechanical means When the small intestines are affected we must give opium and aromatics & depend mainly upon these as internal remedies, until the intestine restores itself. As an adjuvant the warm-bath will be valuable & fomentations or irritants, as mustard & horse radish leaves may be applied to the abdomen. Soothing injections also may be copiously given. The quantity of opium which will be safe at a dose may vary from half a drop to 30 None but the mildest cathartics are safe, as blue pill and aromatic tincture of rhubarb I have succeeded in giving only a decoction of senna & the blue pill [Savage] When volvulus is in the large intestines all our remedies must be given by injection. The warm bath etc. may be used & we may also attempt the restoration mechanically, by means of copious injection repeatedly given & thrown up with force Two cases are related of young men cured by inserting into the rectum & keeping these for a considerable time as spermacete candle with a quantity of opium at its extremity. The first case which I had I treated for constipation with repeated cathartics, which are thrown up etc. The attendants complained that they could not give the injections when I ordered I was ignorant of this case Tried warm bath & every remedy for colic constipation etc. Upon examination at first the colon was apparently wasting at the sigmoid flexure where there was a large tumour which we thought to be a malformation It proved to be a repeated & insolution of the intestines Inflammation had taken place & the whole was adherent, some [illegible] Afterwards I was called too late, to a similar case which upon an examination showed circular appearance Afterwards called in consultation to a child said to have hydrocephalus all the children of which family had died in a strange way. I pronounced the disease not hydroc. but some could not say what was the matter. No treatment was serviceable. Examin showed volv. of small intest. Symptom is above. vide p. 204 The children of the family were subject to diarrhoea & were leucophlegmatic. I afterwards [illegible] the family and was very cautious about cath. giving nothing stronger than blue pill or tinct. rhub. The family raised 5 or 6 children afterwards Case of a student [unaccountable] Dr Munson & Dr Smith at a loss. [Cath.] retained & yet not thrown off by vomiting Sitting by him I observed a rumbling noise Which he said upon my enquiry, he felt & which stopped. I felt the stricture. Spermacite candle, sharpened, opium at [end]. kept up about a [illegible] [renewed] afterwards injection passed up Case of a gentleman on the wharf similar cured 89 Cases. A man over whom a cart had passed without leaving any external injury, died with all the symptoms of volvulus of the small intestines. On dissection the duodenum was found cut entirely in two. One remarkable physiological fact occurred in this case; a cathartic was given by the mouth & produced a regular evacuation from the anus, although the intestine was completely severed. An interesting case occurred to me in which the worm ascaris tricocephalus was found to be the cause The worm lay in this fold of the intestine. Grace Linsey, a delict schoolgirl on was taken with slight in disposition for 3 or 4 days the rejected her food by vomiting then came on constipation with vomiting attended with great restlessness & throwing off the bed clothes, cold extremities, low & small pulse the tongue not much furred, little or no thirst, no tumefaction of the abdomen no determination to the head. She was visited on Tuesday and died on Saturday. A blue pill was given & followed by 15 or 20 grs. of calomel in divided doses No effect was produced though they were not rejected. Opium and stimulant were tried but were not retained. There is no pain but faintness & an uneasiness about the alvine & urinary passages. Both copious and small injection pass up well but produce no evacuation. On Wednesday injections produce stools which are clay coloured. Black vomit came on two days before death. P.m ex. liver very pale little bile in the gall bladder no marks of inflammation cavity containing the intestines very dry as in cholera. Two volvuli were found one in the ileum which was disengaged with difficulty, & one in the jejunum In other cases with similar symptoms I have had supposed there was volv. caused by worms, but have had no opportunity to examine Vide p. 204 [illegible] Lindsay’s case continued. After the examination we accidentally observed some of these worms minute & coiled up among the mucus on the cloths. The worms seem more calculated to irritate the bowel than any other “If it could have been known that the worm was there, perhaps tobacco should aught have succeeded # It is called leg ache in slight affections alluded to by DR Rush Affects the legs, calves of the legs [illegible] continues extends up to the [illegible] coats” It is a disease manageable in its commencement Being a severe disease it calls for decisive remedies The indications are to allay pain equalize excitement & promote peristaltic action by opium by diaphoretics by cath. Cal. in full doses some would call 5 grs a full dose some 10 But if 5 gr. should be given every hour it would amount to a full dose. You may give 10 gr. 2 or 3 times repeated. AT the same time apply warm bath & fomentations not regarding your giving cath. Put drafts at the feet. Follow the cal. with senna, salts etc. But do not be too anxious about the calomel’s operating immediately It is better that it shd lie sometimes in [illegible] vessels With the cal give opium also guiacum & guaicum with dovers powder the latter to act on the skin and the whole to produce a decided [nerve] action affect on the al. can. and on the whole system 89:a. Nervous Rheumatism Infantile neuralgia This is a disease which has never to my knowledge been described in the books, though it may have existed unnoticed I first met with it some years ago, but it is [not] some years since I have seen of a case. It may occur again It occurs in the winter and spring mouths & occurs after exposure to cold especially after the feet have been in snow water. Children are the only persons that I have known attacked # This disease is in its symptoms allied to neuralgia acuta. The affection leg ache is probably allied The attack is sudden after exposure to cold with excruciating pain in the inferior extremities sometimes rigidity of the whole muscular system more or less disorder of the digestive passages (apparently the muscular coat of the intestines is affected) abdomen frequently tense and full stomach sometimes irritable. If the disease advances there is nausea, vomiting, tumefaction of abdomen (appearance of tetanus?_ (coma?) etc. and the patient dies in 4 or 5 days The indications of treatment are to equalize excitement by acting upon the whole surface of the alimentary canal and skin at the same time introduce new action in the system commence with a full dose of calomel 5 to 10 grs or 20 & follow it by senna and manna, or castor oil and enemata “I do not expect that cal. [illegible] I as above will operate at 8 years therefore follow it. Immediately after administering the calomel I put the patient into the warm bath or the feet in to the tepid bath, wrapping them afterwards in flannel or boil cedar boughs in water, roll them in cloths and apply them to the body & feet. Irritants also may be applied to the extremities and to the abdomen Sometimes it will be best to repeat the cal in the course of 2 hours. The stools will be fetid and dark but this must not be considered as an indication for further evacuations as the appearance may be caused by the calomel, and is a sign that secretion is beginning to take place. After producing free evacuations by your cathartic you must keep up a regular course of exciting the secretion by cal. & guaicum with Dover’s powders, especially if pain continues & keep up a diaphoretic action by Dover’s powders calomel and camphor alternately increasing doses if necessary. Calomel and gum arabic, as an emulcent, & calomel and decoction of cedar twigs, as a diaphoretic may be given Give the calomel first in divided doses If cold applications are made to the extremities, to discuss the inflammation the disease is translated to the stomach and death is the consequence I called in the first stages, & am always successful in effecting a speedy cure The irritation of the system is so great that secretion is prevented hence the production of secretion I have been called to patients with [illegible] where little had been done the abdomen was swollen the patient went into a comatose state & died and that too where the disease was not of the most violent form After the bowels are thoroughly evacuated depend upon diaphoretics camphor guaiacum and [illegible] etc. giving so as not to offend the stomach and beginning gradually It is a violent and excessively painful disease and it is a great satisfaction to the phys. to cure it Dark stools [illegible], satisfied “The pain usually begins in the calf of the leg and extends to the contiguous parts. Sometimes it is attended with tetanic spasms & a constant rigidity of the abdominal muscles. The stomach becomes in these cases irritable, and nausea & vomiting prevail. In the progress of the disease the abdomen becomes full and tense, with constipation.” “It should be our leading object to make the muc. men. of al. can. & the cutaneous system active [concert] After the operation of cathartics, if the pain is severe give diaphoretics with opium, as Dover’s powders. Camphor & cal. in small doses as an alterative. If the stools are watery & fetid give opium ¼ gr. guaiacum 1 or 2 grs. camph. 1 gr. Ipecac ½ gr. with cal. repeated till some effect is produced not to salivate, but to this children are not so liable as adults” Young physicians are often called in a case of convulsions as their first case The neighbors & friends (women) have assembled in great numbers and their sympathies are excited. Hence an impression is made with respect to a young physician’s talents which will be of great service or detriment Morbid condition to brain so that ordinary stimuli produce convulsive action Convulsion fits may continue 5 m or from 1 to 2 hrs 90 Convulsions vide costiveness 12:a This is a very common disease of infants. The mortality from it is truly appalling nearly one seventh part of the whole number or deaths of patients under the age of puberty by the bills of mort. in Phil in 20 years Medical writers commonly make two kinds of convulsions idiopathic and symptomatic, the former arising from some morbid condition of the brain and nerves and the latter from some other disease, or from irritation. Children are subject to both kinds & most of the diseases of children may be expected when they prove mortal to terminate in convulsions The causes of symptomatic convulsions are as various as the agent capable of producing irritation though the causes of convulsions in one child will not necessarily produce them in another. The susceptibility to them varies with the age of the child and the peculiarity and degree of delicacy of the constitution. Convulsions may arise from the sudden suppression of evacuations to which the system has become habituated. Irritation from teething is a very common cause. Worms in the alimentary canal may excite convulsions. But perhaps the most frequent cause is the presence of indigestible substances in the primae viae. irritating the nerves of the stomach & through them those of the whole system. Over distention of the stomach, even with food of a healthy quality interrupt the progress of digestion & the food undergoing action [illegible] fermentation “Or the excessive quantity of food may produce convulsions from the mere stimulus of distention” “Dyspepsia is a cause” This is an important maxim in the first children of young mothers Their anxiety of mind will often affect their milk 91 in the stomach, becomes noxious matter & excites convulsions In the season of fruit we may always suspect this as a cause in children old enough to eat it. Calomel has been known to be so irritating to the system as to bring on convulsions Costiveness also is a cause of convulsions in children A change in the quality of the milk of the mother or nurse, produced by improper food or by strong affections of the mind, in some instances is the cause of convulsions in young children. Hence not only the diet of nurses should be regulated, but their minds kept tranquil. It may be observed also that the countenance of the mother or nurse as also those of the bystanders has more influence upon children than is commonly supposed. Even a child but 3 weeks old, will be strongly affected. In some families there is said to be an hereditary predisposition to convulsion among the children. For the treatment we have two indications 1st to remove the exciting cause where this is local & 2nd to relieve the irritation of the system 1st We must enquire into the causes with with care. If evacuations are found to have suddenly ceased they must be restored. The guns should be lanced. Anthelmintics should be given if there are worms If improper food is suspected we must be particular in our enquiries, or we may be misled by a [vague] & general answer. When the convulsions have been brought on by improper food or by food in large quantities recently taken the stomach should be evacuated by an emetic of 5 or 6 grs 4 to 8 of sulph of zinc or of ipecac. # How long should we wait after giving one cathartic before we try another? the child being in convulsions all the while? The equilization of temperature will do a great deal to remove convulsive action Besides the soothing of the [nerves] etrc. Some rely on one and [illegible] or another Oil of a amber is not in my opinion better than many others The oil of amber apparently is the [illegible] the oil of [capal] brought from its E. [illegible] It is recommended to dissolve the oxyg oil in [illegible] [but] it is slow of solution It dissolves readily in either 92 If the offending substances have probably passed the stomach & the irritation is in the bowels, these must be evacuated as speedily as possible giving and injection to begin with [illegible] it to [illegible] cathartic. Sometime it will perhaps be best to give a dose of calomel large enough as to operate both as an emetic & cathartic. Frequently large & repeated doses of cathartics will be needed in order to overcome the torpor produced by an excessive quantity of food. The food also diminishes the cathartic operation is the case with the French [dinner] pill. We may give calomel, 5 to 10 grs. or scammony 3 to 4 gr. jalap 2 to 3 gr. senna & manna, castor oil, neutral salts etc. If dry cathartics fail to produce the desired effect, the liquid should be tried. Sometimes will be acted on by one kind when they will not by the other # If one fails after 3 doses try another & assist with injections Begin with cal. & follow with the others 2. If the convulsions continue after the removal of the cause we must rely upon antispasmodics or even at the commencement. Of these the warm bath must be considered the most powerful remedy in convulsions of children always [illegible] & often efficacious. Its influence is immediate and extensive. Antispasmodics, as pearl ashes or aromatic herbs, may be put in to the water of the bath Of antispasmodic articles a great variety are used. Oil of amber Dr Rush called his sheet anchor in spasmodic diseases. It is useful internally, and applied as an external irritant along the spine. The artificial musk a preparation of amber is in my opinion a better article than amber itself, for all cases where amber is “# Seneca oil is more limpid & pure & approaches nearer to naphtha” Soot is a [illegible] Soot is efficient as a nervine tonic & deobstruent It is sometimes very efficacious in jaundice & dyspepsia It was very popular in Philadelphia with ashes for stomach complaints “The British oil is manufactured in this country from Barbadoes ter & spts turpentine” The nostrils may be rubbed & it may be given internally “also rubbed on the skin” Though so offensive to the small yet children taking the tinct readily potash [illegible] & [illegible] All the alkalies & alkaline earths are antispasmodic. They are not nervine properly. There yet seems to be abundant testimony to their antispasmodic properties. They are to a certain degree tonics. i.e. they have a specific action on the mucus membranes. I have maintained [illegible] they operated by generating excitability a view supported by Jobe vide Hufeland’s Journal in Lond. Med. & Phys. 93 indicated. The mineral oils from whatever source obtained, such as petroleum, seneca oil, British oil, are little inferior to the oil of amber I prefer the seneca oil 5 to 30 drops #. The eympreumatic oils are useful antispasmodic and soot is often given by nurses in decoction Ammoniae in any form is a good antispasmodic A solution of ammonia in spirits often contains an empyreumatic oil of this solution we may give to a child from 2 to 6 drops in an ounce of water. Either the spirt, the carbonate or the aqua ammoniae will be useful in alleviating spasms in children either applied to the nostrils, rubbed upon the skin or given internally. Dippel’s animal oil, a very fetid substance distilled from bones in a state of putrefaction owes to antispasmodic virtue to the presence of ammonia. It is too disgusting Castor and valerian are good articles of this class, but in cases of children they are too bulky & a sufficient quantity cannot be introduced into the stomach. A more powerful article than these is the asafoetida fetid gum 10 or 20 40 drops of the tincture. This is a very valuable remedy to give by injection using for this purpose either the tincture zii or a decoction all the alkalies are antispasmodic & are proper for children. The most powerful is pearlash given by injection, zi to zii in lbis of water I have seen more sudden and permanent effects in cases of spasm produced by injection of this kind, than by any other remedy. It has been successful in cases both of In for [illegible] who have [resumed] in convulsion 2 or 3 days when a variety of narcotics had been given. I have seen surprising effects produced by the injection These applications sometimes fail & we cannot tell to what sort of cases they are Yet we must have a variety of resources if we would be able practitioners Opium is powerful, but though it frequently relieves, yet it sometimes aggravates the symptoms I have given it with great success in paroxysmal convulsions anticipating the paroxysms yet in these it will sometimes fail 94 infants and of adults. Sometimes however this remedy fails & I am not able to point out in what particular “We are compelled sometime to practice [illegible]” instances it is indicated. All the narcotics are antispasmodic. Opium is a powerful antispasmodic and may be given to patients of any age when the condition of the system does not contraindicate it vid. lect on m. m I have given opium where the convulsions were violent & returned at stated periods with fever preceding. When the convulsions appear at regular intervals, as once in an hour, or day, opium in repeated doses may be considered a specific. Counter irritation may be valuable adjuvant in the treatment of convulsions. Oil of [origanum] & similar articles may be rubbed along the spine drafts may be applied to the feet and wrists & mustard horse radish leaves etc. to the abdomen. When the convulsions are frequently repeated in children and become in any degree periodical, a cathartic of calomel given once or twice a week, rarely fails to prevent their recurrence. If this fails I give stramonium or other narcotics If convulsions arise from organic affections we can expect to effect more than to palliate instead of curing the disease. “Counterirritation by mustard, horseradish etc. may be useful” An injection can do no harm can always be administered and if one cannot administer articles by the mouth Irritants may be applied immediately e.g. mustard horseradish garlic N.B. we do not need powerful vesication for the tender skin of infants. Even garlic sometimes vesicates Ammoniae to nostrils & in mouth Be sure that you have [water] enough to [illegible] the child completely for the nerves are apt to think that it is sufficient to half [illegible] child & then sprinkle or scatter water over producing an equal excitement Friction may be applied while in the bath & after coming out [illegible] with dry flannel If the irritants have been applied before the bath taken then off when [illegible] about to immerse in the bath & put them on again if necessary after coming out If the child seems to be in a state of asphyxia the emetic may not take effect; then irritate the fauces the child being lard on its abdomen supported by the hand of the nurse 95 When you are called to a child in convulsions, without previous sickness, direct an injection to be immediately administered and the warm bath to be prepared. if the injection does not relieve, put the child in the warm bath previously adding pearl ash in proportion of zfs to a gall. of water. Let the child remain from 5 to 15 minutes taking it out when it begins to grow exhausted. When taken out of the bath let it be wrapped in flannel & put into a warm bed. Then apply irritants as mustard, horseradish garlic, or aqua ammonia to the abdomen feet and wrists Apply aqua ammonia to the nostrils and temples As soon as the child can swallow give a dose of calomel; If the countenance is pale or livid the cause may be suspected to be some offending matter in the stomach & an emetic ipecac not [illegible] generally should be given. We may often succeed in exciting vomiting by irritating the throat with the finger or a feather & this method should be tried when the patient cannot swallow & is known to have taken improper food or when it is desirable to hasten the operation of an emetic. The child will vomit with much more ease if it is held lying with its belly upon the nurses’ hand, which this supports the abdominal muscles If the child is much agitated at the sight of the water which it is to be immersed, let the tub be covered with a blanket & the patient gradually lowered into the water there will then be no difficulty 96 Epileptic fits are very frequent among children Epilepsy is defined by Good A “spasmodic agitation & distortion, chiefly of the muscles of the face; without sensation or consciousness; recurring at periods more or less regular.” One side is generally more affected than the opposite The limbs may be fixed and rigid with twitching of particular parts. The pupils may be contracted or dilated & the attack may be followed by coma. The attack may be abrupt and without warming or may be preceded by hilarity, or a giddiness or other unpleasant sensation. Sometimes there is what is called the Aura epileptica, a sort of formication, creeping up the body for which the ligature may be applied The fits may be kept up by the constant presence of the cause such as malformation of the brain etc. or, by habit & while in the former case the disease will be incurable, in the latter habit will be very difficult to break up. The causes of epilepsy may be, malformation of the brain tumours of the brain derangement of the system produced before birth by syphilis & rickets or the same causes as those which produce the rickets & in children oftener than after preventing the disease may also arise though more rarely from mere excessive irritability of the system, even’ without any exciting cause of irritation such as indigestible substances in the alimentary canal or suppressed evacuations Among children however epileptic fits are most commonly excited by teething, suppressed evacuations & the irritation of a morbid condition of the bowels or of In scrophulous children remedies for scrofula may be given. [illegible] rickets I have often found advantage from blisters behind the [ears] I have found the cath mode of treat successful for children within the year especially calomel In some cases the most powerful cathartics are required If there is acidity of the passages so that cal. seems to gripe much [illegible] chalk any quantity from 5 to 10 It is immaterial whether the action is chem. or certainly the effect is good The system being very irritable ordinary stimuli or rather a little more than ordinary brings on [illegible] Hence improper articles improper exertions of mind & body etc. Careful management & [illegible] 97 indigestible substances in them. The treatment of epilepsy must vary with the causes which produce it but does not differ materially in the case of children from that of convulsion fits In epilepsy from rickets I have used the cold bath with advantage. In children our attention in the treatment of epilepsy must more especially be directed to the alimentary canal. Cathartics are far more valuable with them than for adults. I have almost always succeeded by means of a course of mild cathartics & joined with one of tonics, such as the tonic solution & the different preparation of iron When called to an attack brought on by offending matter in the stomach and bowels, we should commence the treatment with a strong cathartic in order to thoroughly clear the alimentary canal calomel is the best article but if the bowels are loaded with mucus so that calomel fails to operate we may conjoin 1 or 2 gr. of gamboge & of scammony & 5 of jalap & this though powerful, will yet operate kindly. In the subsequent treatment calomel should be given 3 or 4 times a week; though if there is a deficiency of mucus in the bowels an abrasion as it were the blue pill will be preferable or chalk may be conjoined. Among infants most cases are curable by careful management, both of the physician of nurse The diet should be regulated with great care Generally however there is a morbid appetite, & a sub-[insanity] There is often a difficult, particular waywardness [illegible] like into [illegible] etc. In children more than a year old I have given stramonium so far as to dilate the pupils keeping the child under the operation of it I have not prescribed it to children under 2 yrs or 18 m. I recollect one case in which the convulsion begun to subside as soon as the pupils began to dilate I would not prescribe to [illegible] but to [all] symptoms e.g. tonics all the nat. ton. tinc irr. cap. lead I would give the lead where cathartics, from the excessive irritability of the al. can. aggravate all the symptoms Lead will produce a torpor or sub paresis contrary to this Narcotics also will meet this condition Opium will occasionally, but not generally Why it is we know not but the fact is that phys. do not depend on [illegible] ep. seems to cause a determination to the head 98 with regard to food. This subderangement of the mind manifests itself also in other ways by oddity of appearance gesture & action. A strange propensity for climbing for instance is met with & epileptic children will often be so active & so artful as to be very difficult to manage For more particular treatment see my lecture on m. medical articles stramonium & nit. silver [illegible] turpentine from 10 gtts to zi diluted stramonium, camphor, opium atropa belladonna & most of the more powerful narcotics Arsenic zinc is one of the best of the metallic tonics Actual cautery, [moxa] etc. have been highly extolled “In epilepsy caused by rickets or by the same causes as those which produce ricketts. I have used the cold bath with advantage” “Mercurials followed by mild cathartics [Seontod??] etc.” The child will be still breathing languidly The parents think it dead If you look at it carefully you will perceive as languid treating & looking at the eyes you will often perceive a little convulsive motions of the balls pulse not much disturbed The child continues a few [illegible] with paroxysm & comes out with a scream like an adult from nightmare Not dangerous In a few instances [somerset] Case adult patient [illegible] a chair stands fixed eyes fixed come out with a stare irritable & sub derangement for a few days Afterwards [somersets] “asleep once a sleep twice” Case a girl last year gather up [illegible] [somerset], even 50 times than cataleptic then exhausted This case changed from chorea to catalepsy Repeated bleedings did not change the emaciation etc. 99 Catalepsy This affection when it affects children, is called in poular language still convulsions. It is a very rare disease among adults, but among children I have met with several cases of it In catalepsy the muscles are universally or partially affected with a tonic spasm. The patient remains fixed in the position in which it happened to be when seized appears asleep, is insensible and scarcely breathes. The eyes are commonly fixed, but sometimes have a little motion. The paroxysm may terminate with common convulsions. The length of the paroxysms I have known vary from a few minutes to three hours & in some cases they are frequently repeated The disease arises from the same causes in general & requires the same treatment as epilepsy & convulsions. Cataleptic convulsions sometimes follow other convulsions & in some instances have been brought on by drastic cathartics In adults catalepsy is often followed by irritability & a degree of mental derangement. “Catalepsy arises from the same causes and requires the same treatment as epilepsy chiefly by cath. & antispasm. Sometimes children are affected with catalepsy without it being observed When I commenced practice I thought the notion of still convulsions a mere whim” Dancing before the [illegible] of St. Vitus Dance [illegible] 3 or 4 well persons Comes on gradually parents complain that their children are getting into bad habits Awkward motions The dis. is not benefit. by [illegible] I recollect a gentlem. 40 or 50 yrs told me he had chorea when a child & recollects perfectly the indignation, horror & disgust when so long as to be unable to speak [illegible] Hand carried not to the mouth Sometimes the motions finally become regular “The dancing master” feet blind [illegible] then hands then body then stop like a statue then begin one foot like a [falling] [illegible] 100 Chorea Sancti Viti This is a disease not to be mistaken in its ordinary appearance the voluntary muscles are but partially subject to the well and their motion is convulsive. It occurs oftenest in females of relaxed habit & about the age of puberty especially if they have grown rapidly or been much confined to the needle or to study. In children this disease is often caused by irritation in the primae viae Chorea also arises in some cases from a peculiar irritability of the system in which ordinary stimuli produce convulsive action This irritability may be accompanied with relaxation, or with increased action together with a determination to the head. Indeed it is said sometimes to be connected with inflammation of the brain & hydrocephalus. With those who are predisposed to this disease, particularly if they are females about the age of puberty affections of the mind may bring it or epilepsy sometimes runs into chorea, or alternates with it. Finally, the disease may come on in a very gradual manner, so as not to be suspected, causing a strangeness in the gestures walk etc. which at first is attributed by the friends to the formation of bad habits. This disease is rarely fatal and is not difficult to cure in patients under the age of puberty after that period it is seldom cured. When the disease is of long continuance a great variety of remedies are generally “When I give cathartics in chorea it is not for the evacuation but to produce a new action. All cath. will not act favorably. Hamilton’s views in prescribing cath. are not generally correct.” There sometimes irritation of al. can. from accumulation of feces about the coecum. Hence Hamilton’s plan of purgatives Purgatives will cure but [general] by impression on system It is said to arise from a tonic infl. of brain I have read periodicals have not so I have seen all kinds of treatment tonics, cath narcot. electric. galvan. cold bath etc. etc. Perhaps no disease prescribed for more [illegible] periodically We find one and another article fails and are obliged to go the whole [illegible] off [illegible] narcotic etc. # “In one case of chorea I tried the arnica until the head became affected. The patient began with a decoction of zii the flowers & increased to zfs without any abatement of the disease” Prof T’s [illegible] [illegible] Nux vomica has been used with success in many cases but there are other narcotics which act more powerfully & more certainly I have not used it deterred by [Ba??] [Surrey] who found it injurious for some convulsive cases “Stramonium succeeded in a case following epilepsy” 101 tried and the one last given is apt to be considered as having effected the cure; but I am inclined to think that in many of these cases the disease instead of being cut short by the treatment and run its course and then ceased of itself The most common indications are [for] narcotics and tonics with antispasmodics as palliatives & permanent counterirritation along the spine in some cases. In children however cathartics are commonly indicated; though in general the plan of treating chorea by cathartics, has not succeeded very well in my practice. Dr Hamilton however depended upon cathartics and had better success, though it may be remarked that those who act on that treatment are also the metallic [illegible] When there are symptoms are symptoms of worms, of hydrocephalus, or of inflammation, of the brain or when the disease follows epilepsy we must treat as for those diseases; & if it the chorea is the result exclusively of the peculiar irritability above alluded to, narcotics must be our chief dependance. The principal articles which I have employed in my practice are conium, conium & iron sulphate of zinc, sulphate of iron & other metallic tonics. Various narcotics are used, as the nux vomica in doses of 1 or 2 grs of the seed in pill or 15 or 20 drops of the alcoholic tincture; and antispasmodics as valerian musk etc. may be used as palliatives Cullen’s favorite tonic was the ammoniuret of copper 1 to 4 gr. I have lately used it with advantage in pill 2-3 hours in creasing other tonics are mineral acids, nitrate of silver, bark & the arnica montana #, which is a narcotic & tonic & was successfully used by Dr [Monsen] in chorea” Dr. T’s copy [M. ?] “Sulph zinc 1 gr. may be given 3 or 4 times a day nit. sil. 1/6 to ¼ gr. succeeds best in relaxation of the blood-vessels” “Evacuate the first passages and restore the healthy secretions & irritability of the system by tonics & antispasmodic “I have rarely effected a cure by cathartics though I generally begin with them The cure with antisp. & tonic is slow 2-3 [illegible] with narcotics more speedy but uncertain” A good deal may depend upon the careful management of the patient keeping him quiet & amusing him especially avoiding the irritation of the [pressure] and the impertinent curiosity of strangers The young man in a debilitated “So camphor has sometimes been given in mania to such an extend as to produce epilepsy & sub-apoplexy & this sometimes cures the mania” 103 double the quantity, when the head began to be affected still there was no considerable relief The patient was finally cured by taking the bark in substance zi a day. One case which came on in the gradual manner above described & was brought to a high degree by a dysentery proceeded so far at least as to present the peculiar symptoms of hydrophobia such as horror of water etc. convulsives perfectly [like] that frothing of the mouth etc. died in coma exhausted narcotics tonics etc. no effect excitability exhausted by [illegible] This disease may affect the mind causing it to run upon particular subjects especially upon that of numbers & calculation. I once travelled a short time with a book pedlar who had the odd gestures of chorea & had also this facility in calculation, being in this respect fully equal to the famous [Serah] [Colbourn] [Serah] [Colbourn] though furnished in Europe with the best advantages for education never improved and this result I ventured to predict, when I first heard that he was to be educated. I have seen several such cases. # They have a peculiar articulation & expression of countenance; and are deficient in memory and judgment. Vide [illegible] 12 [illegible] for [Serah] [Colbourn] Case girl at stool good talents studied hard [stand] out of schools [illegible] Cal. narc. cath. tonics operated but [Elateri.] 1/16 gr. once 4 hr in about 24 hours deadly sick nausea prostration vom. purg. disease broken up. It may be diff. to class this A year after similar causes brought on a second attack # Connected with acidity gives great pain not dangerous “This is a troublesome and not unfrequent complaint, arising often from improper food and that stab of the stomach which causes acidity. In a torpid state of the stomach when the healthy action ceases or is feeble, chemical action commences, and the acetous or putrefactive fermentation, prevails according to the contents of the stomach” “If our remedy fails try another for there are no two exactly alike & the judicious physician will discriminate as they are indicated” Among the astringents should be mentioned the rose willow It is one of the pleasantest astringents & is a popular remedy in canker It seems to combine a mucilage Almost any of our wild willows may be used Nitrate of silver may be used It is often however difficult to touch the ulcers and we may then use astringent washes. Rhus glabra and R [typhina] are good astringents vide hosp. [illegible] sub. [illegible] The poison of R [vernex] I have more than once known communicated in more than one instances by using the wood as fuel. I recollect a man’s [illegible] to me on account of an eruption on his legs. I told him he was poisoned. He replied that there could be no cause for it but a pair of the pantaloons lately dyed black. Upon investigation I found that the poison species of sumack had been used by the dyer by mistake for the common one. Young persons are more 102 Cold bathing is sometimes advantageous tepid is seldom proper Electricity has been used. I have seen little benefit from it Setons, issues, tartartar emetic ointment along the spine & other modes of counterirritation, are employed & may be advantageous but where the irritability is great they do injury If the disease is not translatable it is made worse by counterirritation In the treatment of patients affected with this disease, we should bear in mind, that they are the subjects of great mental sensitiveness & irritability The presence of strangers in injurious & the remarks of bystanders upon the patient may cause an amount of mental irritation little suspected. I have succeeded in curing chorea by elaterium though this is an article not mentioned by writers as applicable to this disease. A young man debilitated by confinement as a clerk in N. York was thrown into convulsions and derangement of mind, by a sight of distress while on board the packet for this place Elaterium was given to prostrate the system & break up the habit. It was successful & this led to its employment in chorea. I have completely broken up the latter disease by an eighth of a grain of elaterium & this is the only case which I have broken up vide end of this article Case a female delicate 14 yrs of age had not menstruated had been treated with cathartics, epispasmodics and narcotics, which palliated the symptom. The patient then took arnica for 10 or 12 days beginning with moderate doses (zii to a pint of boiling water being given in 24 hours) & increasing to I have found [illegible] which however was Dr [Rush’s] favorite remedy in females about the cessation of the [illegible] useful Friction antispas. electricity etc. had merely palliated The case then [illegible] to indicate tonics [illegible] the other remedies had [illegible] effect or not recovery rapidly upon bark Sometimes connected with pneumonic affected or with [organic] eff. of the heart In some of these cases [illegible] of copper 1 to 3 gr. rarely more than 2 gr. nauseating article [illegible] in such cases more especially As the [disease] advances sometimes [illegilble] difficult [illegible] swallowing dark [tongue] # [illegible] of them the book pedlar and [Minot] [Sheri] [illegible] [illegible] Both these had this facility in [calculating] # At this time there was not excitability enough left to enable the elat. treat. El. shd not be cont. more than 103:a Ulceration of the mouth in children This is sometimes a troublesome complaint and one that does not readily yield to remedies. It is commonly called canker. The complaint consists of one or more ulcers, which commence with an inflamed point or with a white slough situated commonly near the frenum but sometimes extending over the whole inside of the mouth. The edges of the ulcers are inflamed & elevated & their surfaces excavated, as if they had been eaten out with caustic. The child drools much and nursing is evidently very painful to it. A febricula attends the first stage. The bowels are slow and digestion not vigorous indeed the complaint often arises from improper food and is connected with that state of the stomach which causes acidity Treatment. First excite action of the bowels by magnesia, if there is acidity, blue pill, if there is torpor, or calomel grii & chalk grvi. After this give tonics & astringents as Moseley’s tonic solution 3 to 12 2 to 10 gtts 4 to 6 brak compound tinct. vitriol 4 to 5 gtts & the vegetable astringents as geranium in a [ter] spoonful of water statici spriaea cornus etc. a little laudanum may be added For topical applications we may use the vegetable astringents just mentioned, catechu, kino etc. or the following which has been recommended as very efficacious RX sulph. cupri grs x, cort. peruv. zii acad. gum zi mellis et aquae aa zii make a soft paste to be applied to the ulcers with a pencil. A weak wash of corrosive sublimate may be used Sometimes a mild caustic is serviceable, as nitrate of silver A wash of opium or of opium & corr. sub. is sometimes the best viola pedata makes a valuable wash. Asclepias tuberosa is escharotic. [Post] [illegible] case affected by this poison than old. When young I have often been poisoned myself by boing near the plant merely. Now I can brush past it with impunity provided it does not touch my hands or face. Some persons are not affected at all. The uncertainty of its operation is the only reason why it is not used in medicine. Corrosive sublimate is a good application for the affection of the skin. Yet the disease is a specific one and must generate run through its regular course. A similar disease is produced by the oil of the shell? of the cashew nut Ulceration of the mouth continued “The disease sometimes attended with severe pains, as severe as in tooth ach in which case opium is serviceable. Case of an adult use veg. astring. copper, zinc, opium, nit. silv. & at last corros. sublimate. This last would not be safe in the case of children. Intense pain was produced, which was remedied by holding it in the mouth There was a profuse salivation but it soon ceased and the disease was entirely removed. The surface of the ulcer was destroyed by the sub. & the dis. being local this effected a cure # I have turned my attention particularly to the question whether cal. produces it. I have known the dis. to allow dysentery It was an old notion that cal. broke down the crasus of the blood and it produced a tendency to gangrene. But in the venereal wards of hospitals you will see patients with sloughs all over the mouths and yet no gangrene 104 Gangrene of the mouth This is not a primary disease but a termination of other diseases making its appearance soon after their abatement I have known it follow dysentery and other affections of the bowels, but not any disease in which the blood vessels have exhibited an inflammatory action. It seems to follow diseases of the nerves rather than of the vascular system Children are generally subject of it. This disease is sometimes accompanied with much pain & at others with none ordinarily with little or more. One of the first symptoms is a constant inclination in the child to pick some part of the mouth with the fingers where the gangrene first commences either the teeth gums, less or cheek That part becomes spongy & has a fungous appearance in the course of a few days discharges a [illegible] matter, has a livid appearance & finally becomes black and dry the adjoining parts of the face become tumefied and indurated and the disease continues until a considerable part of the face becomes completely [sphacelated] when the patient dies It may continue sphacelatal in [illegible] etc. the sphacelus being hard dry & black like a piece of leather This disease has been attributed to the use of calomel, but it is entirely unlike that produced by this article, and occurs also in cases where no calomel has been given. # In those cases where calomel has been freely given the disease is not so apt to occur vide case 4th I have known a similar affection occur in the leg of a child, & an irritative fever preceded by rheumatism. Commencing with a spongy and orange coloured spot which afterwards become hard & black, the gangrene livid purpled as though the blood had settled pulse small not much disturbance of the circ. syst. except that it was large # & Prof. Smith & myself could not get down much medicine and were obliged to [illegible] [illegible] with external applications We [illegible] injections and a great variety of external application blisters “When the disease appears with tumefaction I think leeches might be of service. This was called by Dr Smith congestive inflammation. In other cases of gangrene, leeches would not be of service It is not easy to [class] the operation of charcoal It has been called a tonic, but it does not much resemble peruv. bark and we do not gain much by classing it with it It seems to act by generating an excitability Charcoal shd be made of soft wood or of lamp black burned over again in crucible, as is sometimes done by the apothecaries 105 extended up the leg and the child above the knees on both sides died [illegible] No applications seemed to have any effect. The child was irritable & The disease under consideration is nearly allied to that called swelled tongue, but the latter oftener attacks quadrupeds The treatment should be stimulant & antiseptic. Acrids as capsicum may be used & the arum triphyllum accidentally has been known to cure. In one case which I shall relate charcoal appears to have effected the cure. Case 1st The first patient that I saw affected with gangrene of the mouth was an adult female who had the typhus fever. The gangrene commenced on the inside of the cheek & when I first visited the patient a portion of the cheek as large as a dollar had sloughed off out? Great part of the food taken into the mouth passed out at the hole in the cheek. The patient continued in this state for eight or ten days & then died The attending physicians informed me that she has received the ordinary treatment for typhus fever. Case 2nd The next patient affected in a similar manner was a girl seven years of age. Previous to the gangrenous affection she had had a most excruciating disease, which affected the knees legs and bowels I have called it nervous rheumatism & shall notice it in another place. For this she had taken large doses of purgatives 106 calomel & opium, with diaphoretics & tonics. In three or four days the pain ceased and the fever almost entirely disappeared. The guns presented no symptoms of salivation & there was no increase of saliva. In five or six days after the fever subsided the patient complained of severe pain situated in the right temple & extending down to the shoulder like that which had been in the extremities. This was removed by opium to complain of the teeth Soon after she began to work at the molar teeth of the upper jaw, on the right side, at the same time she had a cough which was accompanied with an expectoration of white viscid mucus, and the breath became very offensive, resembling the effluvia of an anatomical room where subjects have been kept a long time. The appetite was tolerable, however the patient took animal food, with relish, and the bowels were easily moved with a little rhubarb the patient world at the teeth until she had removed two of the molar teeth with her fingers, she still continued to pick at the gums. The cheek of the side affected became hard, swollen & red. In forty eight hours a black spot appeared in the centre of the swelling. This spot the patient immediately began to rub with her fingers & soon made a hole through her cheek. The gangrene continued to extend, for a week & at the end of that period had proceeded as far back as the angle of the jaw affected the throat & perhaps the aesophagus The patient then died, having taken food and medicine will until within forty eight hours of her death. 107 Peruvian and oak bark, opium & camphor were very freely given the affected side of the mouth between the teeth & the cheek was filled with superfine bark & poultices of bark were applied to the face In the last stage affected perhaps the lungs Case 3rd Another case occurred in [illegible] subject a child etc. A female child, about 5 years of age was attacked, in the winter of 1813 with “constipation with fever” the complaint being principally confined to the bowels The attending physician gave a dose of calomel and worked it off with senna and manna. A considerable quantity of matter was discharged from the bowels, but from its appearance further evacuations were deemed necessary, and several doses of castor oil were given. On the fourth day I was invited to see the patient. I found her with considerable fever of the typhoid grade, attended with pain in the bowels and head. There was also some swelling of one cheek & the child complained of one or two of the double teeth of the upper jaw on that side. These she frequently attempted to pull out with her fingers & finally succeeded in extracting one of them The cheek afterwards became swollen, inflamed, and hard to the touch & in a short time an orange coloured spot, appeared, upon the outside near the centre, which soon became livid, and the gangrene spreading rapidly, the child died, in eight days from my first visit. She became delirious previously to the cheek becoming livid & afterwards, was comatose. In this case the disease seemed to affect the brain as it does in some cases Bark, opium and camphor were truly given & antiseptic 108 poultice applied to the face as bark [illegible] [fermenting] [poultice] Prof. Smith saw this patient soon after my first visit & agreed with me in the opinion that the case would terminate fatally. He informed me that he had seen but one case of the kind before & that he had attributed that case to an injudicious use of calomel After seeing this patient however, he considered his former opinion as incorrect since in this case there were no marks of the effects of calomel & there was no probability that the single dose of calomel, given in the commencement of the illness, could have produced such an effect, especially when repeated doses of other cathartics, had subsequently been given & had operated freely 4th Case. The next case which I met with was that of a female 12 or 13 years of age, who had the dysentery, in the summer of 1815, accompanied with much typhoid fever & rather a larger discharge of blood by stool than is common in dysentery. The child had been sick for some days before a physician was called. I did not succeed in my attempts to determine the diseased action from the bowels to the surface by diaphoretics & the warm bath, & the disease ran its course and nearly exhausted the patient When it began to decline, the stools to present a fecal appearance & the appetite to return, the friends were There had been some aphthae and I was on a careful watch 109 much encouraged I, however, began to expect a fatal result for I observed, between the anterior incisors of the lower jaw, a fungous enlargement of the gum, the apex of merely a slight discoloration [illegible] & swollen between two teeth which had a purplish appearance somewhat as appears in salivation sometimes. I apprehended gangrene in the case (perhaps from the countenance) and on the first symptoms of it informed the parents, who however, could see nothing alarming in the small swelling between two of the front teeth. I began early with oak & peruvian bark, and at the same time gave freely of brandy and porter. As this course had no effect I applied bark and diluted sulphuric acid to the part affected & also covered with the lunar caustic. Still the treatment had no good effect the gangrene extended under lip and chin became black and the child died Case 5th A child about 3 yrs of age cousin of the previous one [illegible] had a dysentery, in the summer of 1815 [illegible] as there was another member of the family sick in oil uncommon & interesting manner viz the case of chorea resembling hydrophobia was much neglected Her fever was typhoid & the stools sometimes bloody and sometimes of a green mucus. After a course of 15 days and amendment in the symptoms took place the stools became less bloody, the green stools more rare & though the patient was extremely weak but no reduced low as the previous one, the appetite returne After convalescing gradually for six or eight days, there came on a samous discharge from the nose, small in quantity but very fetid which reminded me of gangrene # In this case I examined the gums to see if there was any appearance of salivation and found the gums etc. Two teeth and a piece of the alveolar process came out The disease did not spread so rapidly as the other ones In addition to bark, tonic solution etc. I gave charcoal 110 of the mouth which I had not been on the look out for AT this period the patient inclined to keep her fingers I her mouth. # The gums were very clear and bright & adhered firmly to the teeth, except on the left side of the upper jaw, where the gums of the biscupides appeared discolored and discharged a samous matter. I declared the parents that in my opinion the case would terminate fatally. The child complained of pain in the face and teeth. The cheek opposite the teeth became swelled and hard and of an orange colour. I declared to the friends that mortification had taken place 7 pointed to a black spot on that cheek which happened however to be accidental. I was mistaken for the next day it was found that the black spot was produced by a piece of burnt apple skin, which was washed off This encouraged the friends; yet within 24 hours sphacelus took place the apple skin was in the very spot where I had supposed that I had seen it. This gangrene ceased to spread after the spot became as large as the end of the little finger A circular piece sloughed out and left a hole in through the cheek of about a quarter of an inch diameter The disease abated, the affected teeth and a piece of the alveolar process came away the lips of the wound produced by the sphacelus healed up & the child recovered I recommended the same treatment in this case as in the preceding, but having no confidence in it, & abandoned it and gave charcoal to the amount of perhaps a pound or a pound & a half a day I h ad pudding made of half charcoal & half flour, sweetened with molasses & sugar & fed to the child for the appetite was good. Tonic solution When the disease commences of itself # At the time when the disease called the scalled tongue was very prevalent affecting cattle principally with swelling of the tongue & salivation but to some extent human beings with swelling of tongue cheeks etc. It was found that acrids as [arum] were the best remedies pulse 120 tongue then [brown] fur, considerable pain 111 and compd tinct. vitr. were also given & I commenced the treatment with white oak & peruvian barks & yeast poultice. I attribute the cure, however, to charcoal. Case 6th This was an idiopathic affection. Martha Denison a delicate constitution about 12 yrs of age was attacked in 1819 with symptoms of gangrene of the mouth. There was severe pain in the teeth and jaws oppression at the stomach and symptoms of fever. I discovered the purplish spot in the cheek & “the gums soon put on a spongy appearance” In this case I commenced the treatment with an emetic, which operated favorably I gave it to [illegible] the excitability of the system & gave relief. I then gave stimulants, bark, brandy & opium & kept in the mouth between the gums and cheek a paste made of powdered bark wet with brandy and laudanum. The patient recovered, but the two front teeth of the lower jaw became very loose and there was occasional pain & suppuration for nearly a year. It was about a year before the teeth became firm. [Superfine] bark was occasionally used. Case 7th In 1820 I visited a black child in the last stages of this complaint. At the time when I saw it, it could not swallow. It lived however in this situation for several days I have seen several children in the latter stages Even if there is no chance for a cure it si desirable to be able to give a correct prognosis Trouble has sometimes arisen from the opinion that such cases were produced by calomel A student of this school in [Litch.] cty from notes of my lectures It is known by an [illegible] swelling in the throat some fever etc. etc. In some seasons it prevails extensively & affects persons of all ages. In some seasons these diseases which are called contagious affects one description of persons in another another owing to mode of life etc. “It rarely affects a person the second time. It is said that if it affects the parotid of one side only it may occur again” I have treated cases of this disease with great anxiety. I have never known cases of greater irritation than from this disease “It is milder in children than in adults & is seldom translated to the mammae or testicles till after puberty” “Sometimes the swelling of the testicle is simultaneous with that of the parotid gland or [previous] I have seen several such cases” “The first symptom observed is sometimes a soreness of the testicles. They at length become 4 or 6 times their natural size a suspensory bandage will be necessary” “In some cases there arises suddenly, [illegible] pain in the head pulse full and tense eyes red & all symptoms of phrenitis” 112 Cynanche parotidea Mumps This disease is an inflammation of the parotid glands & is generally moderate in its symptoms Sometimes however it is translated to other parts & is then a severe disease endangering life. It is milder in youth than in adults & in general it is only after the age of puberty that it is translated. The parts to which it is translated occasionally, are the testicles & the prostate gland in males the mammae of females more rarely & sometimes the brain or stomach I have never myself seen a case in which the inflammation was transferred to the mammae but do not doubt the fact Sometimes it appears first in the testicle or at least simultaneously in that & the gland This disease has been considered contagious In my opinion it is not, but on the contrary is liable to be epidemic. When its prevailed in college, the students who left in order to avoid the contagion were attacked as early and is certainly as those who remained. I have noticed that it made its appearance pretty regularly once in seven or fourteen years The fever which accompanies the severer forms is either of the inflammatory or the typhus grade or may be merely irritative & should be treated accordingly When the testicles are affected they are painful swollen sometimes to an excessive degree & sometimes so highly inflamed as to indicate venesection When the stomach is affected “it puts on crythomatic inflammation” and there is hiccough, subsultus tendinum, irritability of stomach and frequent vomiting. # When the brain is affected there is pain of the head & eyes, with hard and tense pulse When the parotid glands only are affected the # These symptoms may come on after the affect of test. [illegible] continued, some [illegible] begin to subside. Dr Rush observes that applying a blister directly on the infl. prevents the system from being affected. I do think blisters keep the aff. in one part “In some seasons an emetic at the commencement or a blister will prevent a translation” Having [learned] the importance of attempting the breaking up of diseases I cast about one year for means to interrupt it & found emetics quite efficacious Stramonium After the testicles have been affected some time and the affection begins to subside the symptoms sometimes change There is subsultus tendinum the stomach become affected vomiting is frequent with hiccough etc. In this case apply mustard to the stomach & feet etc. 113 a generally mild and more inconvenient than painful A translation makes it worse; more so when the translation is to the stomach than to the testicles & most of all when to the brain. Sometimes the complaint is very severe, the fever lasts three or four weeks and the patients are many years in recovering from the disease Treatment. The disease is often broken up by an emetic in the commencement It is best to stop it in the first stages if possible. Mild applications to the inflamed parotids we generally sufficient, such as ammonia or volatile liniment. Dr Rush however recommends blisters to the parts affected, in order to prevent a translation. When the disease effects the testicles & give emetics and apply discutients to the local affection. I also apply blisters to the inside of the thighs. They relieve the testicles when they are swollen & prevent translation to the stomach For a discutient was we may take the following Rx mur. amm. ziii; camph zi; brandy or vinegar 1 gill; water 3 gills. When the inflammatory action is high, bleeding may be practised. It will be well also to use a suspensory bandage. If the stomach is affected in the manner above described we have a difficult case to manage. Epispastics must be applied to the scrotum, counterirritants to the epigastrium to ally vomiting, with effervescing mixtures internally for the Ether is best given in effervescing mixture (carb amm. & lemon juice) Carbon ac. makes stimulants more diffusible & hence causes them to be [used] gratefully and often to be well borne when otherwise the would not be Case 18 grs plethoric parot. gland & testicles swollen head affected Relieved by bleeding decidedly entonic the only entonic case which occurred In the progress of his case stom. became very irritable abdomen sore & tender excessive irritability Did not recover his health completely for years was left dyspeptic & with nervous irritability. To correct irritability of stom. lem. juice [illegible] is most grateful add [doses] of aromatics lime water also external blistering etc. Tonics or metallic tonics myrrh asafoetida (nervine also) hops lettuce These cases are so obstinate and will give you an opportunity to try a great variety of remedies cajeput oil on sugar ol. valerian Though the cases may be apparently alike yet you may find one article best for one & another for [another] A very distressing hiccup, accompanied with spasms might have been mentioned in connection with the vomiting give ether lavender cajeput oil also & valerian which are called terebinthinates 114 same purpose diffusible stimuli as ether given to rouse the system opium ipecac, as tonic stimulant, diaphoretic & nervine 7 finally to allay irritation of the system in general antispasmodics as castor & counterirritants to the extremities effervescing mixtures absorbents, also, as chalk & magnesia, cathartics cantheride & occasionally emetics may be indicated. When the brain becomes affected, the lancet should be freely used, cupping, leeches & blisters, applied to the head of the neutral salt given as cathartics Antimonials nit. [illegible] cal. & neutral salts # Some cases will require a vigorous antiphlogistic course of treatment, others with typhoid fever will require in the [illegible] a stimulating & supporting one, while others again will have symptoms of irritation chiefly & require a corresponding treatment In the progress of the disease uniform perspiration will be valuable Angostura serpentaria, qualified with cardamom or cubebs The old writers recommend also [contrayerva] I have much used it atonics of a peculiar character resembles much agrimonia eupatoria which I have used for it in the country where it is easily obtained the latter is non astringent # “Cold to the head and warmth to the feet avoid mental irritation recovery is usually speedy adults most liable to this translation” I consider [quinsy] an affection of the mucus membranes and [tonsils] nearly allied to catarrhal aff. There is a catarrh aff. nearly allied in which there is a thickening of the membrane. This diathesis may also run into croup Good classes angina maligna with quinsy Here is the evil of nosology For scarlet fever gradually runs into quinsy. We must have science and nosology but still we ought to know the errors which nosology is apt to lend [illegible] & the imperfection of science I have the advantage of not [illegible] having seen the disease but of having had it myself often [illegible] with an unpleasant sensation a relaxation a disposition to hawk and throw off [illegible] In this stage it may certainly be cured After the symptoms comes on swelling, or moderately succeeding to this a chill then swelling with pain perhaps extending to the [illegible] The tonsils enlarge The fever is considered enteric or a common but unless among the labouring men in the country it is more usually subacute One tonsil is perhaps more enlarged than the other perhaps one goes on to suppurate & the other becomes of the natural size and appearance The uvula and fauces swell and respiration and deglutition are prevented. Sometimes ulcers from at first upon the tonsils. Examine each case and do not be too positive in calling it quinsy for this & scarlet fever do blend These symptoms continue 2 to 36 or 48 hours I do not know that I have ever seen a fatal case of 115 Cynanche Tonsillaris Quinsy This diseases has been called “I include also under the term quinsy all effections of the upper part of the aesophagus and pharynx which resemble quinsy in their grade of action” Quinsy is an inflammation seated in the larynx glottis & fauces The characteristic symptoms is swelling of the tonsils Sometimes it is seated lower down in the pharynx than the tonsils, but this does not alter the nature of the disease In some cases it is complicated with catarrh. Those who have once had this disease are very liable to a return of it “The disease common at the age of puberty that before or after” Quinsy may be divided into two stages 1st Predisposing debility indicated by relaxation of the uvula and tonsil, irritation about the fauces, weak deglutition, general languor, with cold chills and uncommon sensibility to cold. This usually continues from 3 or 4 to 12 hours the progress of the disease being sometime rapid and sometimes slow 2nd As the disease advances we find, soreness, pain, redness and swelling of one or both of the tonsils & an inflammation of the mucous membrane of the pharynx; deglutition in exceedingly difficult; there is a severe cough & especially a spasmodic one upon taking food or drink, there is much heat about the throat and about the head & sometimes pain in the head, with a pulse so full and tense as to indicate bleeding. Sometimes there is an excruciating pain in the ear. “rarely cough unless complicated with catarrh” This stage may continue three or four 3 to 7 days days. It terminates either in resolution, or suppuration. of quinsy though I have seen many that I thought would prove fatal. I have known a patient continue unable to swallow for 3 days and yet recover When however it is in the form of swelled tongue it may prove fatal. “An entonic fever may attend, with fullness of pulse much headache excruciating pain extending to the ear; but for more commonly at least in my practice, the pulse is little affected, and the disease is almost not entirely local” # riding on horseback and having the snow melt on his throat & [conduct] off the [caloric] rapidly # and shd carry a piece of alum in the pocket “It is important to distinguish this disease from roseola (scarlet fever) There is an erythema of the fauces distinct from both which yet may terminate in either [illegible] The diagnosis is generally easy but there are cases where it is extremely difficult & indeed there is no definite line believed the two especially in the first stages We must bear in mind that quinsy is commonly more inflammatory that it is not apt to ulcerate & we must be guided somewhat by the prescribing epidemic 116 The suppuration is generally in the tonsils, but in some cases where the disease is seated lower down, a part of the aesophagus suppurates. “The tonsils often remain permanently enlarged” Causes. Quinsy occurs must often in the latter part of autumn & in winter. It is caused like catarrh by alternations of heat and cold by exposure to cold & especially by exposure to cold storms of rain or snow. # Sometimes it is connected with dyspepsia & it may be brought on by irritating substances, as acids, acting upon the mucous membrane of the stomach. I recollect a case of a young man who was attacked with a severe quinsy in consequence of drinking freely of cider made cold with ice Persons who are subject to quinsy should be very cautious about exposing themselves to the alternative of heat and cold # Diagnosis. This disease has sometimes been mistaken for scarlet fever. It is not difficult however to discriminate between them by attending to their prominent symptoms the quinsy being as inflammation of the mucous membrane etc. The first stages however of scarlet fever, resemble those of quinsy, and the difficulty of discriminating between them is at that period much greater. In deciding upon any particular case we must be governed by somewhat by the nature of the prevailing epidemics Chewing camphor will also but not so well break up quinsy in the forming stage but chewing this article is apt to produce pleasant symptoms in the stomach and head Other stimulating applications would probably answer as [guaiacum] & any alcoholic tincture “The prophylactic plan of carrying alum in the pocket etc. has succeeded in hundreds of cases. Indeed when called in the latter stages I often tall them I can do little except to prevent it in future” When the dis is fully formed and when there is much pain in the neck running up into the [illegible] fomentations and the vapour of warm water, the steam bath by throwing over the patients head a blanket and having a teapot of warm water A blister also in the above circumstances will relieve the pain and give great relief An emetic also will be often very beneficial in the commencement of the second stage There is often an excessive quantity of acid in the stomach Case A young man in very hot weather [illegible] a large quantity of cider made very cold with ice was taken at night with great pain and difficulty of swallowing The patient was very anxious to be cured that night A large quantity of tartar emetic was given in excessive doses until a severe orgasm was produced then seeing to [illegible] stricture of the upper orifice of the stomach the [illegible] & secreted from every pore from the violence of the action of the system finally he [illegible] away, and continue in syncope for 10 or 15 mins came out of his fainting fit, the tart. ant. acted as a cath. and the patient was entirely relieved of the difficulty of swallowing [illegible] was merely feeble and exhausted from the prostration of the [tart] 117 Treatment In the first or forming stage. Quinsy may be easily broken up by keeping a small piece of alum say of the size of half a pea in the mouth, and swallowing the saliva until the symptoms have left. Various other astringents may be useful in the first stage. I have given the astringent barks and bitter roots, catechu etc. & have also combined with them the mineral acids chlorine etc. “But all these things will be injurious in the 2nd stage” When the disease if farther advanced a more energetic treatment is necessary. If the tonsils are largely swelled astringents will merely aggravate. IN this stage it may often be broken up by a strong impression made by nausea and vomiting. A strong emetic 3 grs tartar emetic with 8 grs of ipecac # may be given & when the disease arises from a chronic affection of the mucous membrane & acidity of the stomach, an emetic will remove it. In one case I gave half a grain of tartar emetic once in 15 min. until the system was affected, I succeeded in conquering the disease. The patient was in extreme pain & exhausted he fainted previous to fainting he was unable to swallow after coming to, he could swallow & the disease was removed. “But if the case has advanced a little farther, emetic will do no good”s Gargles will in general do harm rather than good, where there is much inflammation. If the irritability is extreme mucilages may be given, and when there is great difficulty in swallowing a cloth wet with spirit and water ay be applied over the mouth and nostrils. Cold water applied externally & internally has been recommended but is dangerous. It may be used however as a preventive. # Eupatorium etc. I have known some phys. generally successful [illegible] breaking up quinsy with cold water but as I predicted there was danger of the translation to the brain he lost one patient in this way “It may be used as a preventive” When the trails are much enlarged it is customary to bleed I would bleed it there was much fullness and strength of the pulse I have often bled and seen it done without the beast benefit still however without any injury as I could perceive “V. S. is important when there is danger of affection of the brain” Scarifying is generally practised. It is sometimes beneficial but often it increases the disease as is the case when a boil is scarifyed I do no t know that I can point out the circumstances which it is beneficial but if there is much irritation I think I would not scarify I have often had my own throat scarifyed without benefit Perhaps it is as often as once in 20 cases that the disease proceeds to suppuration. But if you puncture the swelling be careful to see where you introduce your lancet Case of [young] an opening was made which subsequently caused a troublesome sore the swelling burst of itself In various cases astringents was useful Lister’s [scoriae] (devils bit button snake root) it acts a little like seneka stimulating the fauces it operates considerably in a decoction It has been much used not of much consequence I have not much confidence in gargles The patient cannot gargle But you will give great relief by washing out the mouth with warm water or with mucilages or with a little old spirits and water which is very grateful to the patient Wash off the [illegible] which [illegible] Great advantage is derived from injecting with considerable force with a syringe & washing on the parts Spirits & water will be grateful & reviving 118 When there is redness and swelling but not extreme irritability, scarification is beneficial. If there is irritating soreness or inflammation scarifying will aggravate it After the inflammatory stage is past, blisters may be used I have not been successful in scarifying Bleeding may be necessary, if so it will be indicated by pain in the head and a full & tense pulse. When suppuration is about to take place poultice may be applied externally & vapor inhaled The latter remedy may be administered, very well in the following manner. Put a vessel of hot water in the bed, by the side of the patient & cover him with a sheet. # Touching the tonsils with nitrate of silver, is highly useful If the ear is affected, wet a piece of cotton with strong ammonia and apply it to the dear. it produces a pungent sensation and often gives relief The [liatris] scariosa is used in quinsy in the form of a decoction of the root. It is expectorant, diaphoretic & diuretic. It is called “devils bit” “After the inflammatory stage is established apply blisters” “If the irritability is extreme apply mucilages” “[illegible] & diaphoretics have been used in the early stages and are undoubtedly serviceable” # If you cannot well distinguish where suppuration has taken place, you had better not attempt to open the tonsils When the swelling is great poultices are very beneficial Dove’s [Dury] poultice Devils dung asafoetica Album graicum blown through a quill!! much used by my predecessors in this place Cathartics are proper early in the disease neutral salts if the fever if phlogistic Diet & regimen Give while the patient can drink, nitrous ether & water or a acidulated drink etc. Feed with arrow root etc. for the diet When the inability to swallow has continued sometimes the action is not enteric & the patient shd not be bled nor exhausted by cath. The disease is at this time principally local & from want of food etc. the pulse becomes feeble spirit and water injected into the throat will bring grateful and reviving [illegible] exhausted patient “Apply poultices keep the bowels open with enemata” “Inhale vapour of ether” Various gargles are recommended such as chlorine muriatic acid & water etc. but when there is much action they are apt to irritate Camphorated gargle vapour of camphor etc. There are a variety of these things which are mere palliatives The difficulty of swallowing is not caused so much by the swelling as by the soreness and pain for I have seen patients declare themselves much relieved and able to swallow when upon looking into the throat I could perceive no change in its appearance 119 “Scarification is recommended but I could never succeed with it. If the disease were pure inf. scarif. would be of service but it is an irritation infl. & scarific. increases the pain & infl.” In [illegible] case a free scarific. made the case worse in every respect” There is a stage when scarifying is beneficial when there is redness & swelling but not extreme irritability” “Leeches have been applied in the inflammatory stage externally and to the tonsils. It is difficult to make them take hold on the mucous membrane, but they would be more effectual there” “Suppuration does not take place in one tenth part of the cases. There is free secretion but no solution of continuity upon extermination” “When suppuration is likely to take place use poultices and inhalations of vapour poultices of bread and milk with stramonium are serviceable Gargle or syringe the mouth with spirits & water or camphor” “When the disease is seated farther down in the larynx it is essentially the same” “White dry pigeon’s dung in a poultice with bread and milk was used by Dr [Monson] He thought the phosphate of lime of service” I prescribed it in one case and they mistook for it devils dung (asafoetida) & it did wonders. I did not tell them of their mistake” [illegible] state of fever is a better classification than Good’s. Good separates the disease under different classes making one part are [illegible] disease another an aff. of the blood vessels “Scarlatina & angina are sometimes considered as separate diseases, but they seem to be only different forms of the same disease” 120 Scarlet Fever This disease has been called by various names, among medical writers, though the popular English appellation has been scarlet fever with little or no change. Canker rash however has been its common popular appellation in New England, until of late. Under the name scarlet fever I include both scarlatina mitis & S. maligna & likewise the paristhmitis maligna or ulcerated sore throat called also malignant sore throat & malignant quins. Other names that have been given are Scarlatina mitis & maligna cynanche maligna paristhmitis maligna scarlatina anginosa Enanthesis rosalia is defined by Good Rush a scarlet flush appearing about the second day on the face neck or fauces; spreading progressively over the body; and terminating about the seventh day; fever a typhus. This author divides rosalia into two varieties simples or mild scarlet fever which he considers as being slightly contagious & paristhmitica with an ulcerated throat & a rash not so regular as that of the other variety. This he calls highly contagious Under the name scarlet fever I included both the common mild scarlet fever with a rash & nothing more and the most malignant forms of ulcerated sore throat with the intermediate varieties considering them all as being but different degrees of the same disease This disease with its varieties a naturally associated with pneumonia quinsy influenza etc. Quinsy is an exception persons who have had it are more liable to another attack So too in tropical climates even have what is called a seasoning As a matter of fact this disease is theoretically considered contagious practically not so no precautions being taken the patient not being separated nor the friends and neighbors refraining from coming “The notion of contagion may sometimes be useful in keeping away idle visitors case in Guilford” 121 Scarlet fever often appears as a sporadic and sometimes as an epidemic disease. In general it affects children and women more than men. Dr. Rush’s opinion Some say that the disease never persons over 40 years of age. When epidemic however it attacks persons of all ages, though even then the majority of cases are among children and persons of delicate constitution. In general persons who have once had the scarlet fever are not attacked with it again, still this rule is liable to many exceptions for I have known repeated instances of a second appearance of the disease in the same person. This partial security from a second attack is met with in various epidemics & we may say in general that a person who has had any one of several different diseases the same general diathesis is less liable to have another Scarlet fever is said to be contagious especially in its severer forms The fact is disputed but this is the general opinion. Some fevers are perhaps contagion & among them some forms of this may be so. It certainly, however appears to follow the laws of epidemics and I am inclined to think that the facts which have led to the opinion that it is contagion are better explained by reference to those laws. It is said sometimes to go through the country like the influenza. Like other epidemics, those of scarlet fever exhibit appearances in different seasons, being sometimes milk and harmless & at others highly malignant & dangerous It has occasionally been as # And because blisters applied produced mortification It swept off whole families The fever considered a typhus It is not always so It is sometimes [sub-entonic] always however of a typhous grade 122 as the plague. About a century ago this disease prevailed in this state in its most malignant form, sweeping off whole families. It was called the black canker because the sloughs in the throat turned black & this name, though the influence of tradition, inspires terror in this town even to the present day Since that period the disease has probably been growing milder up to the present time. In 1794 however it was very severe in this town in Litchfield county & over the state more malignant than it has been since. Subsequently to that period adult males have been less affected. The last severe epidemic in this town was in 1803. Though sometimes attended with inflammatory symptom. Scarlet fever as a general rule, is of the typhoid or typhus grade & when malignant puts on the form of typhus gravior or gangrenous state of fever Symptoms. This disorder, when not malignant, nor irregular, commences with ordinary febrile symptoms general disturbance of the functions of the system, chills alternated with flashes of heat & pulse in most cases frequent and soft In severe attacks there is much nausea, sometimes vomiting, pain in the head back and limbs & great prostration The tongue of strength. In 1803 the disease frequently commenced with pain in the teeth or in the ear is the first symptoms In the progress of the disease there is more or less tendency in proportion to the violence of the disorder. In severe cases there is often great heat and dryness of the skin & perhaps the color mordax. In such cases also we frequently with an acrid discharge from the eyes & “When delirium is present it arises rather from inanition than repletion IT is accompanied with subsultus” Swelling of the tonsils is rather a favorable symptom Swelling and suppuration of the glands in the neck haemorrhage for the [illegible] & petechiae may occur 123 nose which excoriates the skin wherever it touches. Irritability of the stomach & vomiting are common & sometimes there is a troublesome diarrhoea. Petechiae may make their appearance. Case at [Hotchk??] town Haemorrhages sometimes take place; & in case of heat on the surface and what Armstrong calls congestive state of the system, a slight haemorrhage from the nose will be beneficial. Finally in the ordinary malignant forms of the disease the breath is very fetid. The epidemic of 1803 was characterised by great irritability of the stomach vomiting & diarrhoea pulse very low and feeble. In this epidemic after obviating the inverted action (of the stomach) stimulants were indicated. The throat is more or less affected from a slight redness to a deep slough. Sometimes there is a high degree of inflammation of the uvula & tonsils at others a relaxation indicating astringents both conditions accompanied with a high degree of tumefaction. A common appearance, in the commencement of the severe form of the disease is that of a white coat upon a part of the tonsils In the progress of scarlet fever, the affection of the throat may be more or less troublesome. It often terminates in ulceration & sometimes in gangrene In three or four days from the first appearance of febrile symptoms or rather on the second day of the fever the eruption appears in the form of a fine rash as described in the definition. In about as many days from its appearance about the seventh day of the disease it disappears Peculiar dulness of the eyes hollow sound of the voice patient appearing much like a night walker The first case of the kind which I saw I had no doubt about The friends had doubted whether he was sick enough to send for a phys. I declared at once that he probably would die. This was a case of pneumonia notha Most resembles measles Ordinarily distinguished readily sometimes with difficulty If scarlet fever is accompanied with a running of the discharges from nose with catarrhal symptoms, and is somewhat distinct in its eruption (hard under the touch under the skin) and such cases occur it cannot be distinguished from measles except by the general character of the epidemic I used to notice in the first commencement of my practice that on the first breaking out of the epidemic the older phys. used to wait and observe several cases before they decided upon the name 124 with branny scales & in ordinary cases the patient is then out of danger. The eruptions, however may vary much & even be altogether wanting the local morbid action being determined wholly to the throat. Ataxic cases will have no eruption. The worst cases of scarlet fever are those which transcend ordinary febrile action. In these the patient is scarcely sensible of being ill, appears dull and languid, his countenance indicates torpor of mind, he has little irritability of mind and is indifferent to surrounding object, his extremities are cold & his pulse small frequent and feeble & perhaps intermitting. Upon examining the throat ash coloured sloughs are found upon the tonsils and uvula. In these cases life is extinguished without any reaction of the system in the course of 24 or 48 hours, unless the tendency to death is obviated by the most powerful treatment. These ataxic cases resemble the ataxic cases of yellow fever pneumonia typhodes etc. which have sometimes been called walking cases The scarlet fever is liable to be confounded with measles, the disease which it most resembles. The marks of discrimination are these. In measles the eruption is less diffused is in pimples or circular dots more pointed & partly distinct & partly in clusters & the pimples produce a palpable roughness of the skin. In scarlet fever the eruption is diffused like erysipelas & consists of innumerable points or specks under the cuticle, intermixed with minute pupulae In some cases the eruption is in irregular patches & in others are uniform flush “Symptoms of pneumonia rarely attend scarlatina” This is one of a series of epidemics. It is usually followed or succeeded by measles & is followed by hooping cough For only it probably existed only as an epidemic now we meet with sporadic cases continually 125 while no roughness is felt, except in a slight degree upon the arm. The two diseases differ also in the time at which the eruption appears. In scarlet fever it shows itself upon the face and arms on the second day, but in measles it is not seen upon the arms till the fourth day. The scarlet fever is distinguished also by the absence of the catarrh, cough & determination to the lungs, suffusion of the eyes & the red and swollen state of the eyelids, which generally attend upon the measles. The latter disease also is generally accompanied by an inflammatory fever instead of the typhus which characterises the former. Still these two diseases of ten blend together so as to make the discrimination very difficult. It is barely possible that they are the same disease, though it may be objected to this view, that scarlet fever likewise is occasionally seen to blend with influenza # Epidemics of influenza are followed by [measles & scarlet] The prognosis in this disease will be obvious upon attending to the malignancy or the severity of the symptoms. In its severer forms it is always a dangerous disease & in its highest malignancy one of the most fatal while in its milder forms there is but little danger. # It is sometimes difficult to determine whether a particular case should be considered as one of scarlet fever, or of quinsy A case of scarlet fever in which there is no eruption & the tonsils are inflamed &swollen can be distinguished from one of quinsy only by attending to the state of the pulse, the prevailing epidemic etc. I have known it appear as an epidemic when it required nothing more than nursing One idea which I wish to impress particularly upon your mind, is that you must investigate the particular epidemic which you have to treat for no previous one will probably have been similar 126 The treatment of this disease must vary according to the diathesis. Epidemics of scarlet fever will differ widely in different seasons & different places & require very different treatment In a country where intermittent prevail the treatment will be different This has been some dispute about using the lancet in this disease. This will depend the degree of inflammatory diathesis. As a general rule emetics are indicated, but not always. Cathartics are generally improper but sometimes are required. In short indiscriminate treatment is as improper in this diseases as in any other. In this milder forms of scarlet fever, we may employ the usual treatment for typhoid fever, & administer those remedies which translate & keep up action and equalise excitement, as diaphoretics, the warm bath etc. For the mildest form it will be sufficient to give mild diaphoretics such as wine whey & elder flower tea, with perhaps a little antimony, acidulated drinks & gentle laxatives As the fever is generally of a typhoid or typhus grade, emetics are of especial importance in its treatment. They affect particularly the mucous membranes and may be repeated in the course of the disease, for the purpose of throwing off the accumulated mucus. The violence of the disease may often be completely broken by an emetic “In some epidemics when there is considerable action cath. of cal. are important especially in intermittent districts Rx cal. & jal. as for remittent bilious fever” “When there is tremor paleness, cold sweats, vomiting diarrhoea, cathartics might destroy the patient We must rouse the patient by counterirritants etc. and then we may go on with the treatment by emetics of ipecac etc. “Dr Rush bled but f.s. is very rarely indicated and in such cases as approach to A. tonsillaris” “Still it [illegible] all forms entonic atonic etc. “If malignant give bark & the min. acids. If the system does not respond give cantharides & capsicum oil of cinnamon cloves or cajeput” 127 at the commencement. All writers agree in recommending them. [Witherin] advises ipecac grs vi & tart. ant. gri for an adult followed by a strong decoction of senna Dr Rush recommends the turpenth mineral 2 to 6 grs with the view of strangling the disease in its birth. Sulphate of zinc is a good emetic & is preferable in the latter stage. It is local in its action & tonic in its effect. It operates speedily and produces less exhaustion. Vomiting by snake root has been practised In the irregular forms of scarlet fever, this practice is more questionable & if emetics are given they must be preceded by stimulants to rouse the powers of the system Cathartics are sometimes needed & calomel is to be preferred The judgment of the physician however must be exercised & the character of the epidemic studied, for great caution must be exercised that the system be not weakened by them & in extreme debility they should be preceded by stimulants. In some epidemics they will destroy the pat.” In some epidemics bleeding may be proper, but the apparent indications for it will generally be better answered by leeches about the throats and [temples] In malignant cases where the powers of life are very feeble no evacuations are to be used. External irritants are to be applied to rouse the system such as ginger mustard brandy a paste of mustard spts. turpentine & aqua ammoniae etc. Internal stimulants must be given Ammonia with bark opium etc.” “Tinct. canth 20 drops once in 2 hours till there is some effect.” “Serpentaria with ammonia acts as a tonic and diaphoretic” Where there is a prejudice against cold affusion with water alone spirits or [illegible] or camphor may be added 128 [illegible] to 4 [illegible] 3 or 4 such as capsicum Capsicum especially when the stomach is debilitated 4 to 5 grs [illegible] Cantharides in 20 drop doses. Ammonia camphor quinine, mineral acids etc. Carb. amm. & cantharides may be given to excite the system & be followed by bark and brandy to keep up the excitement. Diffusible stimulants also may be required, such as chloric or sulphuric ether 20 gtts to a teaspoonful of water for a child. In small children if there is difficulty in getting down medicines the bark may be given by injection, or the body covered with it, by means of a bark jacket. In severe cases, not of the most malignant form, the heat and dryness of the skin are often very great & calor mordax may exist. Cold applications to the skin, especially those of stimulating kind will then be beneficial. The cold bath cold affusion, or sponging with vinegar & water or spirits & water may be used according to circumstances. The cold bath or affusion of cold water may be superseded in case of prejudices on the part of the [illegible] or objections from other causes, may be superseded by sponging the body with vinegar & water If the case is attended with extreme debility and relaxation of the system or if any chills are present sponging must be used & [illegible] with caution. If the cold applications produce a chill or if the eruption comes out irregularly. I should advise the tepid bath to determine to the surface. In the advanced stages of the disease when debility & relaxation are great the vinegar & water should be made tepid & spirits may be added. The rules with respect to these applications are the same as in typhus. In the atonic form of “In children with disturbance of the stomach and pain in the bowels at the same time the eruption not coming out well use the tepid bath It obviates the tendency to convulsions and makes the disease regular In the most malignant forms it is inadmissible” “If there is irritability of the stomach give chloride [illegible] 4 grs 2-3 hours absorbents counterirritants” “In the latter stage of protracted cases emetics of sulphur zinc or copper are very useful” “Withering advises in the typhoid state, after evacuating the stomach & bowels to give senega freely This would be injurious in a malignant case” 129 scarlet fever, the cold bath or cold affusion must not be used IN 1803 I used sponging with vinegar and gave internal stimulants at the same time as min. ac. alc. brandy For children the tepid bath is invaluable in scarlitina particularly in the early stages of the disease and when the eruption is not fully out, or where the eruption is irregular. It is questionable however, how it would succeed in the most malignant form of the disease If there is great irritability of the stomach with vomiting, absorbents and counterirritants are to be used & in malignant cases capsicum, tinct. canth. & care to be given In cases of vomiting saffron & snakeroot If there is much diarrhoea we may give # white decoction with opium, injections of laudanum etc. astringents etc. In ordinary cases, when the eruption has been regular & ends with branny scales, about the seventh day the case is out of danger But when the disease is protracted sulphate of zinc or Moseleys tonic solution is to be given as a tonic. The latter article in a dose from a teaspoonful to a tablespoonful is an emetic in cases of great morbid action. Emetics of sulph. zinc & sulph. of copper have been recommended also of acetate of copper The latter article is also escharotic tonic & caustic. The chlorides chlorates are adapted to this stage of the disease [illegible] [chlorate of potassa] grii to vii “In those cases that require stimulants blisters may occasion gangrenes” “When there is tumefaction of the tonsils use blisters paediluvium & gargle with the mur. ac. especially the [oxymorestic] diluted with 6 parts water” 130 The treatment of the local affection of the throat is of two kinds, external & internal When there is much inflammation about the throat, with the uvula elongated, the tonsils enlarged an inflamed & the pulse full I apply epispastics externally. Blisters, mustard, oil of origanum ol. monard punct. etc. may be applied to the throat Gargles are injurious in bad cases & perhaps of little use in most. Still in ordinary forms of the disease from four to six ounces of any mild astringent acidulated perhaps with muriatic acid may be thrown in by a syringe. The marsh rosemary is considered better than any other astringent. The alum root (henchera amer.) is useful both as a gargle & given internally. For the latter purpose sweeten it & add a little brandy When there is not much tumefaction & considerable relaxation of the parts stimulating garbles are good, as capsicum & brandy astringents may be added. In gangrenous cases quinine is good if it can be got down. In the latter stages of the disease it may be useful to touch the ulcers in the throat with nit. silv. “Vinegar & lemon juice may be used as a gargle” “If the ulcers are thick and leathery apply nit. sil.” “I have seen the brain affected and much spasmodic action subderangement pain in the head and all the symptoms of hydrocephalus with a bloating of the whole cellular membrane pulse frequent & extremely quick and all the marks of irritative actions For 3 or 4 years I have used tinct. dose in 4-5 & sat. tinct. canth. in 10 3 or 4 times a day giving also the tonic solution and keeping the bowels open” “It produces eruptions on the skin, heat dryness & soreness of the fauces febrile action & if continued 8 or 10 days I think it would be useful. I would try it were the disease severe and epidemic, whether I thought it contagious or not” 131 The sequel of scarlet fever is dropsy. In children especially an anasarca and sometimes an universal dropsy comes on after the disease has subsided. The first two cases which I met with were in the severe epidemic of 1803. I treated them according to the direction of the books, with bark & brandy opium & lost my patients Considering this as an affection of the absorbent and nervous system I treated the subsequent cases which fell upon my hands with tinct. cantharides & tinct. digitalis The digitalis allayed the morbid action of the exhalents & absorbents & the cantharides acted as a diuretic. “Give of each 2 or 6 drops every 3 or 4 hours It [opens] [illegible] in these cases the effect of irritative action hence the propriety of digitalis Hanneman proposes to prevent the recurrence of scarlet fever by the administration of moderate quantities of atropia belladonna an article which produces an eruption upon the skin, similar to the rash of scarlet fever. The influence of belladonna, upon this hypothesis is similar to that of vaccination in preventing small pox. The termination of the chain of actions in health in some diseases & if we say nature cures the disease then we may say when the tendency is [inevitably] to death that nature commits suicide. The latter is true of this disease Yet if this chain of morbid actions is broken up by a powerful impression the constitution will take on its ordinary action Scarce any disease is more curable when taken in season yet it would not be proper for a physician to say he could cure all cases then pretending infallibility I shd doubt whether Good had ever seen the progress of a single case. He says nothing about the first stage. The tendency of the disease is to destroy the patient not by infl. or irritation but by suffocation from a foreign body in the trachea The stages run into one another, and yet a phys. watching the progress would naturally divide it into three stages Always curable in the first stage unless complicated with some other disease rarely in the second almost never in the last yet I have known cases cured in the last stage The peculiar sound of the cough is alarming (in the first stage) even to those who have never before heard it Dr [Hesark] I have been told divides the disease as I have done into 3 stages and directs to give 2 grs. tart. ant. combined with ipecac. I shd give for the effect not according to the quantity. I put out 3 or 4 gr and give till the effect is produced rarely over 10 grs 132 Croup This disease has been called in America by the popular name of hives which is probably a corruption of heaves called rattles The name given it by Good is empresmia bronchitis. The most common scientific appellation has been cynanche trachealis or angina trachealis The persons attacked by croup are I have never [illegible] 3 and [illegible] almost exclusively children from 3 months to 12 years old # in one instance I have known it attack a person 60 years of age When it occurs in adults it succeeds other diseases I have known 2 or 3 cups of [illegible] “Croup sometimes though less frequently than most diseases, blends with other diseases as catarrh” Some have considered the disease as contagious, but though a few facts appear to favour the supposition, they are not numerous enough to establish a general law. Croup usually occurs in the winter and spring, when it is brough on by exposure to a cold and damp atmosphere. Children upon the sea coast are more subject than in the interior of the country, because exposed to more variable weather and more frequent [thaws] & notwithstanding the greater warmth of the climate on the seacoast For when the air is filled with vapour, the caloric of the body is conducted off with more rapidity than in a dry atmosphere, even if the temperature of the latter is colder. # It is principally confined to persons under 5 years of age though it sometimes attacks persons of all ages, and It is not precisely entonic or atonic & hence might be called specific in peculiar It is said that in croup the exhalent arteries are affected & in catarrh this [illegible] vessels Whether the different vessels are affected or not there is certainly a different action “I have thought croup might destroy life by coating the entire surface of the lungs with a mucous or membranous coat thus preventing the decarbonization of the blood” “I have never seen croup without more or less spasm; & probably in fatal cases it is always a spasmodic contraction that closes the passage to the lungs which is only diminished by the membrane. I never saw a case on the other hand of what is called spasmodic croup which did not if neglected put on the membranous & inflammatory form” A similar [membranific] inflammation exists in the duodenum 133 Croup is a specific disease of a peculiar kind and is never malignant. It comes on with all the symptoms of pyrexia and consist in an inflammatory affection of the mucous membrane of the larynx and trachea, which causes a remarkable shrill sound in breathing & a ringing cough by which those who have seen the complaint cannot fail to recognise it. The proximate cause is a peculiar inflammatory action of the system, determined to the exhalent vessels arteries of the trachea and bronchial vessels, where there is produced an exudation of coagulable lymph similar to that which forms on the membranes of closed cavities from inflammation & entirely different from secretion of the mucous glands whether healthy or unhealthy. This coagulable lymph which is thus exuded, always forms a membrane which lines the larynx and trachea, if the disease proceeds to a fatal termination, and causes death by suffocation. This appearance is always found in the tracheae of those who have died of the disease. The membranific inflammation distinguishes croup in its nature, from catarrh which is in all its varieties, an affection of the mucous glands Most diseases attack in the night “Diseases are cowards, they mostly attack in the night” Rush. “The peculiar ringing sound of croup is made in [expiration] that of hooping cough is inspiration” # As is the case when respiration is impeded by any foreign body there is a great deal of irritation # when the nose discharges [illegible] [illegible] it bronchial vessels secrete mucus and a new action takes place the patient will be apt to recover # The patient was subject to asthma and the croup was neglected until the latter stages finally died + “I have known this to happen only once In this case the friends were not alarmed because the child had been subject to catarrhal affections & the symptoms received no attention till the last stage” # Frequently appears to be [illegible] in the very commencement of the disease 134 This disease sometimes come on like a catarrh and continues two or three days without any alarming symptoms, until suddenly, & often in the night the peculiar symptoms of croup appear. At other times the first symptom of the disease is a severe paroxysm of suffocation attended with the hoarse & shrill ringing noise made during expiration like air through a broken tube & the peculiar ringing cough. The cough in its progress is attended with more or less of spasmodic action. # It is always dry; and when it becomes loose or when mucus is expectorated the disease is broken up and there is no further danger # It rarely continues so long as five days and is sometimes fatal in twenty four hours. Sometimes, though rarely the membrane of coagulated lymph is coughed up. I have met with but one case + In this the membrane was thrown up three times, at each subsequent time forming lower down than before # No disease resembles croup so much as suffocating catarrh yet there are obvious marks of discrimination The latter disease as I have seen it is not attended with much cough and the difficulty of respiration is not in paroxysms but constant & commence with the disease. The pulse is often quickened and when the system is prostrated may be low. # In suffocating catarrh the powers of life are to be raised by external irritants & excitement equalized by the inhalation of the vapor of [illegible] of warm water etc. “Mustard” “If pulse tense bleed” From the earliest of my practice I have been in the habit of dividing it into 3 stages [illegible] that they are perfectly distinct, but [illegible] person would naturally take this view Quiet between the [per.] apparently not much affected during the paroxysms Between the paroxysms pulse natural & eyes bright. You will know this disease in this stage only during the par. Parents in this place know the disease in this stage and send forth phys. In this first stage, the disease must be broken up by a powerful impression upon the system This may be done many ways Some are partial to a [illegible] & some to another “That which is best administered is best” A local effect upon the stomach will not answer I have relied more upon tart. ant. than any other & found it answer all reasonable expectations. I have preferred it to any other I have occasionally used other [illegible] I have found seneka better as an auxiliary than as a commanding [remedy] 135 Croup may be divided into three stages each of them requiring different treatment. 1st The forming stage 2nd The inflammatory stage & 3d The last or suffocating stage 1st In the forming stage, the cough is severe & hoarse & occurs in paroxysms of from five minutes to have an hour in interval. “There is little or no fever” The pulse is regular and small, & sometimes trembling. The patient is often chilly. In this stage the disease may with certainty be cured “I have not lost a patient & have not saved one in [illegible] when not called till the second paroxysm had commenced” In the treatment of this stage we must depend upon emetics. Large doses must be given moderate ones do no good. A dose should be administered sufficiently powerful to affect the whole system and call into action every muscle. We must be regulated not by the quantity but the effect for we must calculate to overcome the diseased action completely by the operator of our remedy. I have given three grains of tartar emetic to a child three months old, & kept up the action by the large doses of seneka repeated every half hour for six or eight hours Tartrate of antimony is the best emetic to commence with and may be given in a dose of from 3 to six grains of strong tart em. After its operation a constant nausea must be kept up by seneka or some similar article, for some time in order to prevent a return of the disease. The seneka excites a new action in the system. It may be given in decoction. Take zfs or zi of bruised seneka to half a pint of water, & boil away a quarter. Give a table spoonful for a It has so happened that with us the [serpentaria] has not answered so well as tart ant. It acts on the fauces perhaps more [illegible] than tart. ant. but does not affect the system act upon the skin & determines to the surface so well as tart. ant. We have not used it however except in the latter stages & perhaps have not given it a thorough trial Sanguinaria vide p. 212 has been used 50 perhaps a hundred years. Three generations of physicians in one locality have used it and relied on it in croup with as much success as upon other articles These mode of using it was in strong decoction without weight & give a table spoonful until the desired effect is produced till vomiting is excited or the disease is broken up There are however forms of the disease where it fails even in [illegible] “Much has been said of the good effects of calomel Give in large doses 20 – 30 [illegible] acting as an emetic it is serviceable but when catharsis is produced, the emetics would fall in with the catharsis. I never could in such a case make the strong impression on the system what I [illegible]” 136 does once in half an hour or as much as the stomach will bear. Seneka has been relied upon by some as a specific in croup, but it is inefficacious when inflammation is present, being a stimulant, and it is too slow in its operation for the first remedy. After giving it as the first article, other emetics seem to lose their influence; acting as cathartics; but after the violence of the disease has been broken up by other emetics, you may avail yourself of the nauseating & deobstruent effects of the seneka & effect a cure. Dr Rush preferred the turpeth mineral 2 to 6 grs as the first emetic. The physicians in Wallingford for 5 years make a strong decoction of sanguinaria, and give it until emesis or a cure is effected. This article may be used instead of seneka in the way above directed In connexion with these means the warm bath and fomentations may be used as adjuvants. Much has been said of the good effects of calomel in this disease You cannot rely upon calomel for the cure of the disease It is too slow in its operation. Never give calomel until you have broken the violence of the disease After emetics have operated and you have availed your self of the operation of seneca & sanguinaria and the disease still exists, give from 5 to 10 grs of calomel By this producing an orgasm in the system more powerful than the disease & continuing it until the latter be overcome, croup may be cured with more certainty than most other diseases. All diseases should be attended I know that there are some very respectable physicians who rely upon calomel For this purpose they give very large doses and produce [illegible] & [illegible] I should prefer it as an auxiliar. I have often used it but after the emetic or with the emetic or before the emetic A variety of other men [illegible] India tobacco which though not allied in botany are so in their operations The common tobacco is generally applied eternally to the pit of the stomach. Lobelia acrid & emetic loses some of its virtues by drying In its recent state 1 gr will often excite full vom. Indeed I have known vom. prod. by merely chewing the capsules & [illegible] without swallowing by the impression upon the mouth Dose of tinct. 20 drops to a t. sp. according to age Other acrid narcotics as veratrum & colchicum may be used In this forming stage bleeding is not indicative by the pulse, nor by state of the system and you will obstruct your efforts to excite a powerful effort of the system if you bleed 2nd stage In this acrid emetics are injurious seneka is too stimulating Sanguinaria had I have seen all the symptoms aggravated by bloodroot in [illegible] the high entonic stage # “If the disease is complicated with a similar affection of the stomach & duodenum give calomel & other cathartics” 137 to in the beginning & it is owing to the imperfection of or our art that every disease is not broken up in its first stages. When however croup supervenes upon other diseases, it is more dangerous. “Those who practice in the country rarely see the disease in the forming stage. I had one winter 20 cases of croup all in town recovered most of the in the country died” 2nd Country practitioners however seldom see this first stage which I have just been treating of when the tongue is not discoloured, the fauces have a natural appearance the pulse is unaffected respiration natural & ordinarily no inflammation about the tonsils. On the contrary they too generally arrive when the disease is in the second or inflammatory stage the disease has effected in which the bloodvessels the skin is hot and dry, the face flushed, the pulse tense & sometimes full the tongue furred, respiration between the paroxysms difficult tongue furred, respiration between the paroxysms difficult and the cough so severe as to threaten immediate death vide p. 213. In this stage we should immediately bleed from freely from a large orifice the arm or jugular vein freely, even until syncope is produced put the patient in the warm bath & let him also inhale the steam of warm water, and give calomel and other cathartics. # Never give emetics in this stage until after depletion by V.S. when we may give 4 grs. of tart. ant. in a table spoonful of warm water & apply epispastics to the throat” in the commencement apply a blister” I dread to be called in this stage of the disease, for it is the almost always fatal venesection sometimes succeeds but very seldom. I would not apply leeches cupping would be better & perhaps friction might be serviceable. Digitalis has been recommended, but In this stage inhale the vapour cover the child & nurse in a chair with a blanket In this stage cal. & cath. may be given In the first stages I have conserved it very unfortunate to find my patient under the operation of a cathartic It feels as if my hands were tied The excitement is of a different kind from what is wanted And emetics are apt to produce hyper cathartics Where the dis tends to the [illegible] the [illegible] a specific. This is known by the cough being less hoarse, by fever, by constipation fever more intestinal membrane will pass off from the duodenum I was formerly disposed to cure this form of the disease [illegible] & described it as such In the second stage epispastics over the whole chest also diaphoretics and tepid bath When the cough is milder and beginning to be loos after being principally broken up in the first stage give cal. in 2 or 3 gr doses once in 2 or 3 hours In the 2nd stage remedies have been given to obviate the fever & digitalis has been used with good effect It was used as a depressing agent It operates by its narcotic power however. here refrigerants are of little efficacy In what may be seen to be the last 138 I have not used it. It is at best but a doubtful remedy in inflammatory effections though calculate to remove more irritations. Sanguinaria diminished arterial action like digitalis and operates powerfully as an emetic. I have not succeeded with it in the last stages of croup & have not used it in the first. [?ronchotomy] has been proposed, but does not promise much benefit, as the disease is seated below the place for operating. “Dr Smith did not recommend it” After depletion and especially after the disease assumes a bilious form you may give powerful cathartics The pt. begins to thrown his head back death may happen any moment 3d IN the last or suffocating stage* you may give emetics of turpeth mineral sulphate of zinc or even corrosive sublimate to throw off the membrane. Something may depend upon changing the emetics & sulphate of zinc may be tried. The cold bath is said to have been successful in this stage, but the fact is not well authenticated. I have used calomel and the warm bath with advantage. Child of Mr Culver [last] in chronic stage “I regret that I have not tried affusion of cold water in the last stage. It is said to cause the membrane to be thrown off & to procure relief even in the very article of death” vide p. 182 *”In the last stage respiration is constantly laborious head thrown back pulse often irregular & intermittent sometimes strong” Chronic form “Sometimes though rarely the disease is only partially subdued I [illegible] on in a chronic form. Calomel vapour best tepid bath are the appropriate remedies” 139 Angina Laryngea Empresma Laryngitis of Good, q.v. for a definition & an account of the disease In this disease the symptoms differ somewhat from those of croup, though the cough is similar The disease is seated in the larynx glottis and fauces & the characteristic symptoms is swelling of the tonsils. The cough is spasmodic and is excited by taking food with drink in this respect also indistinguished from croup. The disease is more violent and rapid than croup, as the inflammation being seated in the narrow part about the glottis produce suffocation sooner. The respiration is more difficult than it croup particularly between the paroxysms This disease more commonly affect adults The first case that I saw was that of an old man in whom the disease was brought on by exposure to cold after a pneumonia From a relation of his symptoms I prescribed seneca which only exasperated the disease, so that when I saw the patient he was unable to speak or swallow. A small red spot appeared on the tonsils. venesection, epispastics, pediluvium, inhalation of vapor etc. were resorted to with no abatement of the symptoms. Venesection was performed a second time & as soon as the patient was able to swallow, 4 grs. of tartar emetic were administered. Some nausea and vomiting with considerable catharsis followed. The vesication “Angina laryngea is mor apt than croup to recur several nights in succession” “The slough were thick and leathery. Sloughing even under blisters. In one instance blisters did not heal in 4 mo. Lunar caustic applied to the tonsils & uvula & inflamed parts proved serviceable # “In one case of A. laryngea I gave sanguinaria It was too acrid and increased the cough etc. It might do good if we could avoid the local effect of its acrimony” 140 was extensively returned & the patient recovered. Much the same treatment is required as in croup but it should be more prompt and with earlier venesection. For the inflammatory stage comes on earlier and the disease runs a more rapid course Last year this diseases differed in its appearance from the former years It has often followed certain affections of the tonsils called black canker. The tonsils are inflamed in black canker and sometime covered with a leathery crust. This comes off and leaves an ulcer. If the inflammation extends to the larynx, symptoms of croup supervene Case of black canker. Two called in the last stage gave blood root with disadvantage # Still at this late period calomel and other cathartics in large doses produced free evacuations and the child recovered Cathartics appear to do better than emetics. In one case after giving cathartics I used the vapour bath and applied a large epispastic over the whole sternum. Though at so late a period the disease abated. A large slough however was produced by the blister which required three months to heal. The morbid action on the skin being similar to that of the tonsils Vie p. 187 Sometimes comes on with a sudden paroxysm of suffocation sometimes gradually “Distinguished in its commencement from croup by the quantity of mucus in the bronchial vessels” “in the case which I have attended, not much febrile action attended the disease” Proximate cause a morbid action of the lining membrane of the lungs accompanied with a viscid secretion of [mucus] By vomiting the disease may be relieved & apparently cured but may appear again in the course of an hour The quantity of mucus is greater than in any other catarrhal affection” 141 Catarrhal epidemic resembling croup Peculiar catarrhal affection resembling croup suffocating catarrh This disease is characterised by a severe hoarse cough, much resembling that of croup. The disease is distinguished in its commencement from croup by the excessive quantity of mucus in the bronchial vessels which causes the suffocation The disease resembles croup likewise in the mode of its attack which is sometimes sudden with symptoms of suffocation, and at other times gradual with paroxysms of coughing and intervals of perfect ease The turns of coughing are so violent in this disease as to produce a livid colour of the face. The extremities evident determination to the head are cold and the head is hot from the quantity of blood thrown into the vessel of the head by coughing. The evacuation from the bowels are healthy and among children with no disease which I am acquainted affect the bowels so little ass this. The proximate cause of the disease is a morbid secretion of mucus on the lining membrane of the lungs & trachaea with obstructed perspiration. The quantity of mucus thrown out by this membrane in this disease is astonishing After the disease is fully formed, great quantities of viscid mucus may be brought away by vomiting, to the great relief of the patient for a short time, and yet within an hour the patient will appear to be suffocating from the the quantity again collected in the bronchial vessels In the commencement of this disease, the indication is to break it up at once by a powerful emetic, of tart. ant. unless the system The principal indication is to break up the disease by a powerful action on the skin on the stomach the duodenum and the fauces It is best affected by tart. ant. which is more difficult in its action than [ipecac] though is very delicate constitutions ipecac may be practicable # prevent accumulation of [mucus] The bowels shd be evacuated not for the purpose of curing the disease but for the prevention of an accumulation of feces which would be irritating In all diseases of the lungs examine the state of the skin and particularly that of the lower extremities for perspiration upon the upper extremities [only] may be a part of the disease I have known the lives of several patients saved by the use of the vapour bath I formerly [illegible] and used [illegible] for transmitting vapour by transmitting air through boiling water It was old practice to apply cat-skins fowls split open (to the feet) etc. with the intention of communicating vitality 142 is too much weakened to bear this treatment. This is a general principle viz, if possible to break a disease in its commencement by means of a strong orgasm. Often the emetic is to be repeated, and it may ever be necessary to give four or five emetics 1 gr [illegible] tart. emet. each in the course of a day. After the disease is somewhat broken up, and epispastic applied upon the breast will assist much in allaying its violence # If the disease still continues or if when first called we find it fully formed and powerful emetics inadmissible the primary indication will be to open the pores of the skin and keep up a gentle perspiration, by small doses of antimonial wine to which may be added in all quantities of camphor by elix. [illegible] & in some cases tinct opii by fomentations and especially by the warm bath and the inhalation of vapour. To affect the latter object the child may be placed in the warm bath & a blanket thrown both over it and the nurse, so as to keep the child in an atmosphere of vapour. Long continued perspiration invariably relieves the symptoms. I have known an instance in which the skin of a sheep warm from the animals body was wrapped round the naked body of the child with beneficial effect. In small children when the stomach ceases to be excited by emetics the throat should be irritated by a feather or the finger, when we wish to produce vomiting For we must never rest satisfied with merely endeavoring to palliate the symptoms. In small children also the mucus should be wiped out of the mouth by the finger or a cloth This disease prevails most in the winter and spring months & does not occur every year. The first patient that I treated for the disease suffered from it a year. I gave mercurials & finally the silver pill (nit sil) 143 I was puzzled with the first cases of this disease which I met with. Some of them continued for weeks and months I was obliged to use perspiration, by warm bath to vapour bath emetics etc. I determined to break up the next cases in the commencement with tartar emetic repeated until full vomiting was produced walking my patients. This plan was more successful A s a general rule break up all diseases if you can “The complaint is epidemic or rather endemic. It has been mistaken for croup, but it differs As croup formerly occurred no mucus was raised in the earlier stages, and when there was an excretion of mucus we considered the disease cured But of late years the two complaints are somewhat blended. Mucus is thrown off sometimes without permanent relief” “There is often in this disease a disturbance of the brain and nervous system resembling epilepsy or chorea produced by the cough” A distinction was formerly made by some writers and some practitioners, between hooping cough and [chin] cough the latter being a spasmodic cough without the hoop. Such a distinction will not hold good there is no difference “Linneas and Rosenstein attributed it to an insect others to malaria” There had been a very severe winter & no one had left the island for months 144 Hooping Cough Pertussis Called also chincough This is a disease which generally attacks children yet occasionally, adults are the subjects. I have known persons of 60 years of age affected with it. As a general rule also it does not affect persons a second time. I have known about 20 or 30 exceptions & among them was the late president Dwight at 60 years Hooping cough generally appears as an epidemic. With respect to its origin there is considerable difficulty in making up an opinion. It is said to be contagious to arise from a specific contagion which affects a person but once. Dr [Dewers], however, says “We confess that we are inclined to believe that it depends upon causes of a more general and pervading influence that contagion.” Dr Cullen asserts that he has said a disease which though evidently arising from chincough contagion never put on any other form than that of common catarrh. In the tenth volume of the medical commentaries DR Willey gives an account of the breaking out of the disease on Block Island under such circumstances that it would seem that it could not have originated from contagion. When the disease prevails many become effected where every precaution is taken” When the disease has been extensively prevalent I have not been particular about keeping patients apart, perhaps however it is best for prudence’ sake to consider the disease as contagious and to treat it as such. One fact I have noticed that in particular seasons may have the disease who have had it before.” Some suppose that it is contagious only in the first stage others in the second “Some think it caused by malaria or animalcular” “The stricture may be overcome by not attempting to inspire, but to expire till the lungs are emptied the pat. can then inspire without difficulty I have known persons subject to this kind of hooping without cough Adults are sometimes attacked in the night with paroxysms of suffocation they start from bed when the recover their breath there is hooping but no cough, at least at first The more they struggle to catch breath the greater the difficulty there seems to be a spasm of the glottis Let them make no effort to inspire but expire the little air remaining in the lungs & they will bye relieved at once. The disease is liable to recur bathe the feet at night give paregoric wine whey diluents The disease is not described 145 Some suppose this disease a peculiar inflammation of the mucous membrane of the trachea and lungs, others that it arises in the bowels This disease often commences with the symptoms of ordinary catarrh & continues without alteration for some days. Sometimes the peculiar mark which gives this cough the appellation of hooping & distinguishes this disease from every other does not appear until the 3d or 4th week It is impossible however to distinguish the disease until this peculiar hooping makes its appearance. When the disease is prevalent it will be safe to treat every severe case of catarrh among children as one of this disease The phenomena peculiar to this disease may be the described. Several frequent expirations are made in succession by spasmodic coughing, and a full inspiration is then necessary to restore air to the lungs. The air as it passes rapidly into the lungs produces a loud sound called whooping The sound however is made more by the structure of the passage than by the rapidity with which the air is drawn into the lungs I have known persons subject to this kind of whooping, without having a cough caused by a spasm of the muscles of the trachea larynx? to which adults are sometimes subject. (Goods laryngismus?) A similar sound is also made in croup, when the air is expired after the passage becomes constricted The patient is aware of the coming on of a paroxysm of coughing by an unpleasant sensation in the throat, & The cough is violent in proportion to the shortness of the paroxysm 146 it is common for children support themselves during its continuance by changing to a chair or other support near them. During the paroxysm the blood is returned with such violence to the head as to produce a livid colour of the face & often in bleeding at the nose. Very violent paroxysm sometimes in young children terminate in convulsions or death The paroxysms continue until a quantity of mucus is thrown up from the lungs or the contents of the stomach are evacuated by vomiting They are short in proportion to the facility with which the mucus is brought up or rather in proportion to the rapidity with which it is secreted It is the secretion of mucus, not its removal which gives relief to the irritation of the lungs Many suppose that this mucus which is generally in considerable quantity is the cause of the paroxysm of coughing instead of the effect of it. The peculiar irritation of membrane in a paroxysm of coughing produces a secretion of [illegible], and when a sufficient quantity has been secreted it is coughed up like the secretion of tears from an irritated eye and the paroxysm is relieved “The mucus sheaths the part & the ceases” The disease continues from one to six months It is often kept up by habit. The cough is usually more violent by night than by day. Violent cases are often attended with considerable fever and in the worst cases respiration is laborious between the fits of coughing. The disease may terminate by apoplexy or suffocation or by ulceration of the lungs and hectic & sometimes by permanent visceral obstruction “or apoplexy or suffocation” Whooping cough is not dangerous to adults and I have never known a child over two years of age die with it. It is most dangerous to infants and the younger the It is usually dangerous to children within the mouth It is apt to wear out very young children especially if they are of a scrofulous tendency It is frequently accompanied with a morbid sensibility and irritability of mind and hence in the latter stages a change of air and of place is salutary as in cholera infantum The same despondency of mind takes place as in chol. inf. q.v. The disease is a fever spending itself upon the lungs and trachea, and affecting also the glandular system Some phys. think this dis. like common catarrh, is always inflammatory in its commencement, and requires antiphlogistic treatment. But we know that pneumonia may be highly typhoid & require treatment opposite to [enteric] pneumonia. If infl. of the lungs exists the antiphlogistic treatment shd be adopted in its fullest extent I have seen antimony as efficacious in this dis as in pneumonia. In general perhaps mild antiphlogistic diet & treatment will be proper. In some cases I have thought the veins lost their power, and in such cases the blood [illegible] has been prescribed & with advantage It is a catarrhal fever at first and to be treated as such 147 child the greater danger in children under the age two years The anger, to be apprehended from the disease will also depend upon the debility of the child when attacked. The cough may be violent and attended with frequent vomiting yet of the patient’s appetite be good there will not be much danger to be apprehended. A moderate hemorrhage from the nose is often salutary Treatment. If the disease is mild and the constitution good little need be done with the way of treatment. But if inflammatory symptoms supervene with a tendency to pneumonia the antiphlogistic treatment must be adopted. Bleeding will often be advisable. A small quantity of blood taken from the arm proves serviceable. In general greater effects may be expected from the application of a few leeches to the breast or neck than from bleeding at the arm but when decided symptoms of pneumonia appear, & the blood seems to be transmitted with difficulty through the lungs. I would recommend venesection. In this case also the bloodroot will be the best article for internal administration In most cases the disease comes on like a catarrh, and should be treated as such, with mild antiphlogistic regiment [illegible] important part of the antiphlogistic treatment of this disease is the keeping the bowels open. Costiveness frequently attends the disease & should be carefully avoided. In general it is better to obviate this symptom by diet as far as it can be done Begin with antimony in small doses 1l or 2 drops ant wine & in [illegible] For very delicate children however it may be better to give ipecac Almost all the writers recommend vomiting [Best] 148 rather than by medicine. The best cathartics for the indication are those which excite the secretions of the stomach and liver. Sometimes the disease has a tendency to produce congestion of the liver and obstruction of the mesenteric glands and in that case also mild mercurials should be given and their use continued as long as any symptoms of congestion exist. All the medical writers on this disease recommended vomiting in the first stage Tart. ant. is in ordinary cases the best emetic. Sometimes for a child from two to six months old two drops of antimonial wine will be an emetic dose while for another of the same age 20 or 3o drops may be required. In affections of the lungs children will bear antimony better than in those of the stomach and duodenum. In some constitutions antimonial emetics produce (in this disease) a sort of spasmodic stricture other emetics also may produce this effect a symptom which must be relieved by diluents and opium In general antimony in small doses may be given to children of any age, either by itself or combined with a small quantity of paregoric or any other mild preparations of opium. Given in this way it removes febrile action and congestion of the lungs, and determines to the surface When the disease has proceeded with You may see the fontanelles swell in such cases. I recollect a child in the whooping cough going into the country I told the parents not to suffer the child to be vomited. A physician in the country said the child must be vomited of course all the books directed it in whooping cough He vomited the child. It went into convulsions and died # Here insert the recipe for hire syrup or compd sys. of squills p. 150 I have known the lives of some patients saved by this antimony internally had lost its power produced no effect 149 violence for some time and there is much determination of blood to the head, threatening convulsions or apoplexy from distention of the blood vessels, or when the patient has become debilitated vomiting by emetics should not be practises or but cautiously. When the system and particularly the stomach has become debilitated. Ipecac is preferable to antimony, given in emetic doses, or in small quantities as an alterative diaphoretic and antispasmodic. And in the latter stages likewise on account of the debility, sulph. tinc. is a good emetic using 5 or 6 grs. with as much of ipecac If there is not much febrile heat, and there is much viscid mucus in the stomach and lungs, and emetic of squills is often serviceable # particularly I [illegible] phlegmatic temperaments syrup of squills vinegar of [illegible] In this disease if there is danger of convulsions from vomiting, blood root and similar articles should be given. The hive syrup or compd tinct. of squills may be used In children under three 6 months, whooping cough may be much relieved (respiration being promoted) by vesication on the breast. A blistering plaster may be applied but I have more generally used the following. Rx common or mild tinct. canth zi targ. ant zi Dissolve the ant. in the tinct. & apply a linen cloth with the mixture till [illegible] or partial vesication is produce & then dress with simple cerate In this way we have the vesicating & irritating qualities combined. This external use of tart. em. was recommended 20 years ago, in the Lon. med. & ph. Journ. This disease may be cured in its first stage but it ordinarily runs a regular course & the treatment is generally palliative brown mixture You will perceive that this is a strong decoction of seneka and squills, with a large proportion of tart ant. shd be given cautiously 4 to 30 drops Narcotics have been strongly recommended e.g. atropa belladonna & hydrogen of the former for 2 gr of the leaves in powder Alibert recommends the fresh bruised root 150 A popular remedy in whooping cough in Godfrey’s cordial, made of molasses and water with a little laudanum and oil of [illegible] “Hive syrup” (or compd syr [illegible]) is made as follows Rx bruised seneka root & squills zz z8 water lb 8 boil and evaporate one half strain and add honey 4 pts boil to lb 6 Add tart. ant. gr.i to every ounce Give for an emetic 8 or 10 20 drops to a child 4 mo. old & repeat the dose every 15 or 20 minutes until vomiting is produced The “brown mixture” is as follows elix. pareg. zi; ant. wine zfs; ext. glyc ziii pul. gum ar. zii wat. zvi trit. & boil dose from ½ teaspoonful to tablespoonful This has been very extensively used This disease has been prescribed for more empirically than most others; a fact which proves the difficulty of curing it It is a popular notion that it must “run its course” & under the influence of this many parents object to its being prescribed for. Undoubtedly this like every other disease must “run its course,” if it is not cured; but this is no reason why the cure should not be attempted. Ammoniae asafoetida (especially if the cough is kept up from habit) 1st antispasmodics 2nd tonics # An emetic is occasionally administered with advantage “I have prepared this from seneca oil also from gun copal” 151 2nd In the second or chronic stage tonics & antispasmodics are indicated. Sulph. of copper or of zinc tinct canth. cinchona, arsenical solution etc. may be required to rouse and support the system & as antispasmodic tinct. asafoet. petroleum Artificial musk etc. and also the narcotics, as hyoscyamus, conium, stramonium, belladona arnica, opium etc. When the cough is kept up by habit, # asafoet. is often administered to children with advantage. It may be given in tinct. or decoct. & if it cannot be given by the mouth it may be thrown up in an enema, using 10, 20, or 30 drops of the tinct. It is a valuable [illegible] the taste is less unpleasant than the [illegible] Artificial musk or oxygenated oil of amber was first introduced by Prof Hufeland of Jena as a specific for whooping cough and has since been found very useful in other spasmodic diseases vid. Lon. M of ph. J. vol. 1: p.181 van Swieten’s comm. etc. Rx nit. ac ziiifs cl. succini zi. And the acid gradually, ina temperature of 100 [degrees] or in the sun. Prof. Hufeland triturated x or xii grs. in a mortar with a few almonds & diluted with z 5 or 6 of water & gave a teaspoonful every 2 hours to a child a year old. This preparation was very celebrated and very effectual, for a time, but afterwards fail was thought to be ill prepared. The truth was the diathesis had changed. Probably it will be as affectual at [illegible] time I have given the above article in tinct. Rx zii of the oxyg. [illegible] [illegible] lbfs alcohol dose 10 to 12 20 gtts It is much more soluble in ether. I frequently dissolve zi of oxygenated amb. in zi of ether dose 1 to 2 drops on sugar 152 It may be prepared indeed of any strength, to suit the convenience of the physician. Probably gum copal oxygenated would answer the same purpose as amber as there is every reason to suppose that the two are essentially the same amber being gum copal mineralised Case of a vein of olibanum or Frankincense found in S. America. Opium is not indicated in this disease except when it is qualified and its action determined to the skin by antimony ipecac or camphor. Hyoscyamus is better than opium for in the cough it produces no constipation and the tincture is very pleasant. I have not however used it in this disease. Conium has been recommended by writers of the first respectability, but later authors do not speak of it with much confidence. It deserves a trial when other things fail. Alibert recommends atropa belladonna 1/6 gr. of the root or leaves powdered & given in milk I have used I have more confidence however stramonium in the [illegible] & think it preferable most of the narcotics to any other narcotic It is peculiarly calculated to remove spasmodic action depending upon irritability of the system or kept up by habit From the relief obtained by its use in asthma I was led to employ it in this disease and from those cases in which I have tried it I am of opinion that it is a very valuable remedy in it The ripe seeds of the stramonium are best the full dose of these for adults is gr. ii for a child 1/10 gr. or more according to the age Mercurials occasionally blue pill rhub & ipecac enough to keep up a gentle excitement in the bowels Not unpleasant to the taste An old [illegible] Chalmers ([illegible] of silver) recommends sulph. cop. & tinct canth in wh. cough # [ago] more used than any other Lately the ox. bis. has taken its place dose the same used for irritating cough & irrit. of stomach 153 Carb. potash is a good antispasmodic used externally and internally. It is not only antacid & antispasmodic but it appears to me to produce a peculiar excitement upon the stomach and aesophagus, which makes the more susceptible to the impression of other articles. Pearlash zfs & water z8 with cochineal enough to colour the solution has been considered relied on by some physicians a specific. The cochineal merely colours the solution. is an article from which I never could perceive any medicinal effects when used alone. I have tried the experiment & could perceive no medicinal effect from it Tonics. I have given the sulphate of zinc more than any other tonic in this disease, and have experienced the greatest benefit. Sulph. tinc given by itself, sometimes produces spasmodic action, the effect I attribute to its being used in substance & hence I always give it in the form of Moseley’s tonic solution. This preparation is both conic and antispasmodic is easily taken and retained on the stomach of very small children Sulph. copper possesses properties similar to those of sulphate of zinc. It is administered in the low stage of whooping cough. In this place the preparation of it called compd tinct vitr has been used according to the recipe in the 10th vol. Duncan’s Commentaries in doses of 3 to 30 drops according to the age of the patient The oxide (or flowers) of zinc & also bismuth formerly much used in spasmodic cough 30 grs have been occasionally used 1 to 3 grs 1 to 10 to an adult The Peruvian bark is a good remedy in the last stages. The only objection to it lies on the difficulty It sometimes happens that the physician is not called in until the latter stages. As one resort we may have recourse to irritate along the spine It is an opinion very extensively prevalent to that it is of no consequence what kind of food a child takes when he has the whooping cough But great attention shd be given Removal from sea side to country and [illegible] country to sea side either is beneficial 154 of administering to small children, a quantity sufficient to produce any considerable effect. This difficulty may now more be overcome by using sulph. quinine ¼ gr to 1 gr Dr Chalmers of South Carolina recommends a combustion of bark, sulphate of copper and cantharides Tinct. cantharides has been long since recommended for whooping cough. It is useful when the system requires an inflammatory diathesis to be produced. Its action on the stomach is probably similar to that which it has in cases of gleet and leucorrhoea the stomach being in a relaxed state & requiring to be excited to a healthy inflammatory action Irritants, as oil of capsicum canth. [illegible] or ol. orig. or vol. lin. rubbed along the spine have been used in the latter stages. They should be tried when you have reason to suspect that the spinal marrow or the nerves proceeding from it are affected. Attention should be paid to the diet of children in the whooping cough avoiding potatoes, oily foods etc. Change of scene & change of air especially by riding should be resorted to in bad cases, to tranquillise the patient & furnish mental excitement. Sometimes the little sufferers will be excessively irritable constantly worrying and teasing until this is done requesting first one thing & the other to be done. It is the worst of such cases, medicine does little good, even the irritation produced by administering it may counteract its beneficial effects. violent palpitation throbbing of the heart a soft flowing pulse and a jarring feel of the pulse under the finger ([illegible]) (The French call an enlarged heart hypertrophy I object to the [name]) For this I have given nit. sil. 1 or 2? gr. (in the chronic stage of [illegible]) Digitalis & also [languinaria] (tinct. 2 or 3 gtts.) This article is dangerous for children because it accumulates in the system Lead has been recommended I have been doubtful with respect to its propriety in affection of the lungs etc. # Pneumonia typhoides 1815 the system seeming to lose the power of [illegible] the blood and the bloodroot was given to promote venous absorption The digitalis might probably be given in such cases but is not as well adapted. I used the blood root and found as much benefit as could or [expected] from any article 155 If the patient having the whooping cough happen to be teething the treatment recommended for dentition should be employed The patients are very liable to have an inflammation of the lungs from taking cold in any stage of the disease & in such cases the remedies for pneumonia should be administered, such as antimony bleeding epispastics, bath etc. The disease I think sometimes determines to the head & produce a relaxation of the sinuses & [illegible] likewise produces a relaxation of the ventricles of the heart the immediate cause being the violence of the cough In such cases I have used lead, but not in sufficient quantities to enable me to recommend it Iodine has been recommended 2 or 3 doses 3 times a day Nit. sil. languinaria & digitalis When in the progress of the disease the circulation becomes much affected the pulse frequent, soft, flowing with occasional intermission respiration high frequent and laborious, with a bloated and sometimes analogous to # a livid countenance, the blood root has done more than any other remedy not failing in any instance to give relief & palliate sympt & in some cases the relief has been permanent. I gave the bloodroot repeatedly, the last spring, 1815 to my patients in the whooping cough. To a child a year old 5 to 10 or 20 grs of the dried root, according to the urgency of the case, infused in 6 or 8 teaspoonful of boiling water. Give a teaspoonful every hour, until vomiting is produced or the patient relieved. Children Sometimes the dis. will be very mild and yet leave the system in such a state that a slight subsequent disease will carry off the patient e.g. in 1815 the dysentery attacking children would often be very slight and yet would carry off every one who had had the whoop. c. in the spring. The attack would be mild and insignificant of dysentery and yet the pat. would go into a [illegible] very speedily like cholera Elaterium has been recommended I shd be cautious in trying it except in very vigorous children I can speak with confidence of arsenic. Excepting occasionally prussic ac. I know of no remedy which so completely cures the wh. cough except prussic acid in some cases. Case child 2 gtts night & a [illegible] in a weak countenance pale, eyes dull face bloated muscular strength weak muscles soft & flabby Parents much [illegible] cough gone recovered colour & strength upon bark I have known several such cases and have known no ultimate injury result from this practice Yet parents are afraid 156 who had the whooping cough that spring were very liable to be carried off by the dysentery of the following summer none died in 1815 of the disease but many in consequence of it, with hydrocephalus and dysentery Prussic acid dose 1/3 of a drop to begin with and arsenic occasionally cut this disease entirely short; and these are the only articles which I have known do so, without leaving a vestige of the disease behind. The former is a dangerous article to use, from its want of uniformity and strength Fowler’s solution of arsenic gtt more [illegible] is safe but does not answer so well in the first stages. If it makes the patient feeble livid bloated & with swollen lips etc. it must be stopped & perhaps bark administered. It has cured the cough in the second stage. Dose 1 drop 1 or 2 drops twice a day. Sometimes is only palliates Case. June 1815. A child of Capt. Totten’s a boy of 5 yrs of age rather full habit had been affected with the cough for a fortnight before I saw him I found his pulse very frequent soft convulsive & with intermissions face swollen and livid, circulation much increased on slight palpitative [illegible] motion of the body in the symptoms aggravated to an alarming degree by a paroxysm of coughing. Previous t the disease a remarkably even tempered and pleasant child he was not on the contrary very irritable. Trifles irritated his mind, and when irritated, all the symptoms of his disease were aggravated. He took an emetic of ipecac, with The sequels of this disease are numerous Sometimes the heart is affected as above and continues so for years. Sometimes the glandular system is affection. Sometimes the lungs. There is a lady in Philadelphia who had (under my care) suppuration of the lungs whoop. cough now healthy hence never despair The stomach and abd. visc. are sometimes affected in a chronic way requiring dandelion mercurials hop [illegible] etc. It is very tedious to attend children in the chronic stage an account of the excessive irritability When bath recommended Cold bath doubtful. I have known patients killed by being brought from the country and plunged in the sea bath “Good speaks highly of rhus [illegible]. It is given to produce a distinct action on the system which shall overcome the diseased action. It determines powerfully to the surface and has a powerful exciting effect on the blood vessels while it does not produce a determination to the brain. I should not recommend this article and it is so uncertain in its effect. On one person it will have no effect at all, when in another it will cause swelling of the eyes, blindness, fever, & great irritation 157 but inconsiderable & temporary relief. He was directed to take the bloodroot every hour, as much as the stomach In relieved the violent symptoms would bear. It was continued for two or three days, and the palpitation of the heart was much abated, the circulation was less irritated, & the livid colour of the face was gone still did not cure When costive he was benefitted by full doses of cathartics. because the system was [illegible] deranged heart lungs etc. I considered the case a fatal one and expressed that opinion to the parents. The cough and other symptoms continued though in a less violent degree disease chronic an epispastic was applied to the chest very irritating (changed clothes often in the day [child] run upon various subjects) Patients strength began to fail and tonics were given white vitriol bark cantharides Finally the patient refused to take any medicine and was left to his own appetite called obstinately for it took cake for food for several days then baked pears then [illegible] Afterwards recovered but was unable to run “for some years” without a palpitation If this disease should again prevail I think I should atropa belladonna as a prophylactic. As the disease continues the stomach may become very much debilitation and require compd powd of [contragerva] cat carilla etc. etc. “Ledus palustra are narcotic” It is not certain that the dis. did not exist before It may have existed before but no general account given of it. It may have been known in diff. places by diff. varies and it [illegible] have been known than the diff names meant the same disease Diseases are not apt to appear suddenly. Still at this period, there [illegible] cause operating for the increase of the dis. Belly usually large and limbs small Joints unusually large Often morbid cravings of appetite Yet the same causes operating in a higher degree produce cretinism There is no difficulty in recognizing the disease You will be struck at first sight with the large size of the head the blue [veins] of the forehead paleness of countenance as you cast your eyes down you will notice the large joints 158 Ricketts This disease according to Underwood was first noticed in England in the year 1628. It is said to have immediately succeeded the increase of manufactures, when people left the villages to settle in large towns, where they wanted exercise and a pure atmosphere Children are rarely attacked with this disease earlier than the sixth month and not usually until after that period. The symptoms are soft flesh muscles & cell. sub. relaxed general relaxation of the system paleness of the countenance unless the face is flushed with fever, which when it exists is of the hectic kind a fever of irritation pulse, usually quick and feeble, tumefaction of the abdomen appetite and digestion bad tendency to acidity veins of the head [illegible] and blue the sutures of the head not firmly closed head large fontanells unusually open joints large in bad cases all the bones of the system enlarged & softened One effect of the disease is that the teeth are cut later than usual. Ricketty children are usually precocious in intellect. Their mental faculties are developped more early but are not capable however of so much improvement, as those of others. Evolution of the mental faculties does not proceed with the tardy progress of the assimilating function The child learns to [illegible] very early and exhibits an acuteness of intellect beyond his years with the exception however of those cases so severe as to have a tendency to cretinism It is a common saying that very forward children are not likely to live long and the precocity of scrofulous & rickety children may have contributed much to the production of this impression. Too much heat may produce an indirect debility Undoubtedly aff. the brain & nervous system Give mercurials occasionally Do not produce salivation and do debilitate by mercury Frictions are very efficacious exciting the skin The reasons why friction are not more successful is that they are not perservered [illegible] the al. can. etc. The cold bath is the only strengthening remedy which acts suddenly No effect can be produced by any medicine equal to the astonishing effect of exercise & amusement in many cases of chronic aff. of stomach & bowel. 159 The causes of this disease as in some instances a predisposition transmitted from debilitated parents sometimes a syphilitic taint of the parents In others bad nursing the children being kept wet and dirty and confined in close & damp apartments or if the child has been carefully fed and kept clean debility produced by confined air too great warmth, too great variety of food and as some think too much saccharine matter in its diet. Inanition may be a cause. The disease prevails among the Alps and is perhaps there caused by the combined influence of cold and moisture This is a disease of debility nearly allied to scrofula & cretinism affecting the viscera of the abdomen generally, the lymphatics and the [isseous] system. The chylopoietic viscera are probably first and afterwards the mesenteric & lymphatic glands generally the indications are to give tone to the system and excite healthy secretions The diet should be dry and nutritious and such as is not only easy of digestion but rather stimulating and the bowels kept open by cathartics which act on the secretions. A dose of calomel with a little ipecac will be useful. The cold bath should be used every day Take the child out of bed in themorning bathe & return. If the Cold bath of salt water is [illegible] tonic patient be very feeble it should be begun with at of a temperature of about 80 [degrees] and gradually used colder The child bath is equal to all other remedies It is more tonic if made of salt water As a substitute for exercise, frictions will be very useful But exercise in the open air should be like whenever the weather is good in a carriage or on horseback and exercise should be so managed as to afford amusement and mental The [guephalin] [polyapt] & also the gr. marg. (which is less odorous) are also used Their agreeable odor if there is no other advantage will prove grateful stimulus & promote healthy secretions Take the child out of bed and plunge him in water (about 70 at first) and replace him in bed Yet in exhaustion of fever the cold bath gives a shock from which the system will not react but yet in the debility the cold bath is highly beneficial whether we can explain it or not. It may be necessary to vary the tonic And it is desirable to have a variety of tonics to [chorea] from also carb iron & tinct. carb. iron ac. fer. alkaline solut The sulph. zinc is not inferior to iron and is not subject to the inconveniences of iron not producing inconveniences Mosely’s sol. The compd tinct vitr. although apparently [illegible] is yet certain in operation and has been long used in this vicinity A tinct. of potash is thought very useful to rub the body with. It is a popular remedy & has sustained its reputation in this neighborhood for many years Lime water made of caustic lime is more tonic than the carbonate That made of shells is thought better being pleasanter than that made for stores probably not as pure but containing muriate of lime. Be careful to see that the shells are thoroughly burnt so as to fall in powder when 160 stimulus by the sight of scenery vegetations, flowers etrc. The patient may even be benefitted by being carried in the arms into the garden and amused in this manner. It must not be forgotten that this cheerful excitement has a powerful effect on the secretions. Feather beds should be prohibited. They are too enervating, and hard ones should be used in their stead. Beds made of the sweet fern (comptonia [asph??folia]) are popular & do very well. They not only from their hardness check the profuse perspiration of the hectic diathesis, but correct the acid smell of the sweat which is very common. IN general heat should be avoided as too relaxing I have rarely failed of curing the disease by the cold bath as the principal remedy, using tonics however as occasion may require. The tonics which we may use are sulphates Phosp. & mur [illegible] 3-10 grs of zinc & of iron muriate of iron martial flowers of iron etc. and the plan has been tried of applying finely powdered bark eternally in a quilted jacket of flannel. It is difficult to give bark in substance to small children. Astringents may be indicated & there is often a degree of acidity so great as to indicate a free use of absorbents The alkalies as pearlash may be beneficial internally & frictions with pearlash & water zfs to a pint may be recommended. Of late iodine has been given in doses of from 2 to 4 drops of the alcoholic tincture 3 or 4 times a day, given mucilage or other convenient vehicle. This article when persevered in has cured a great many cases. It should be [given] at first in small doses & the quantity be gradually increased or a disgust towards it may be created Phosphate of [illegible] was popular Forgetting that the deficiency of [osseous] matter may be defect in the action of the secretions Though the theory was wrong yet the practice was found beneficial absorbents Give a solution of the acid of about the strength of lemonade The phosporus is preferred to the phosphoric quenches in the water you will then have, not as is too commonly the case merely smoky water but lime water of full strength These preparations are called tonics by Good called stimulants (too loose as use of the word) Long before I had any explanation in [illegible] I thought I observed that these articles created a susceptibility to the operation of tonics apparently as generating excitability 161 It has been supposed that the proximate cause of this disease is a deficiency of phosphate of lime with bones but this is an effect, caused by want of action as those vessels which secrete this substance. The proximate cause, as it is called, is in this case the disease itself. In consequence of this notion burnt bones have been much prescribed. They are probably useful not as supplying the matter of bone but as an absorbent & perhaps as a tonic Acids especially the phosphoric have been given. Phosphate of lime has been used with benefit muriate of [illegible] and barytes were formerly much prescribed. The worst cases are those of children born of syphilitic parents for these tonics mercurials and the cold bath will also be the treatment. I give them corr. subl. 1/30 gr with no injurious effect Nearly allied to ricketts and often as sequel of it ricketts often running into it Sometimes appears with ricketts sometimes afterward Ricketts occur with the year. Scrofula occurs later. Ricketts children are more generally of a scrofulous temperament The tendency may exist in the parents and yet be developed only in the children from the causes of bad food [illegible] pain etc. These swellings may continue in children of 5 or 6 [illegible] or within the year with little or no change but increasing of size in spite of poultices filling the whole neck I have found poultices apparently injurious promoting the relaxation but blisters would stimulate and bring on a suppuration. The pus will not be healthy but curdy and whey like The edges will be ragged, not unite readily, and will leave a bad scar. Scrofula, ulcers are said to be distinguished by a smooth overlapping margin. the disease may continue for months and years with little or no change of it does not attack a part essential to life as the lungs, producing tubercular consumption attacking the liver producing a peculiar atonic infl. I have seen cases of scrofula that were [entonic] They were injured by tonics and benefitted by cal. and ant. They would have borne bleeding 162 Scrofula This is a disease of the lymphatics and affects persons of a peculiar temperament this temperament is characterized by a fair, thin, translucent skin, light hair, blue eyes, sometimes black hair and eyes delicate fullness of lips & nostrils usually texture of skin and cellular substance general laxity of muscular fibre usually delicate organization mental faculties developed early on in ricketts. Person who have been affected with ricketts in infancy are after affected with scrofula in after life. This peculiarity of constitution, when a morbid action is superadded, gives rise to the following symptoms First small swellings appear about the neck, slow in their progress & with an imperfect suppuration. Small holes form in the swelling and discharge a subpurulent, watery and flocculent fluid. These scrofulus ulcers when fully formed are distinguished by smooth spongy and overlapping margins & by very lax granulations. The disease forms tubercles upon the lungs, liver kidnies & ovaria & causes a great enlargement of the mesenteric glands This morbid condition and action may be transmitted from parents to children. It prevails especially in cold and variable climates exists most in large manufacturing towns where it is caused by bad food and air, want of cleanliness all of them debilitating causes It is sometimes also in persons predisposed, a sequel of other diseases particularly of small pox, hooping cough & measles Treatment. more may be accomplished in the treatment of scrofula by diet, exercise, sea air etc. than by remedies. Scrofulous swellings should be treated by Avoid cold vegetables & watery diet give animal food articles containing nitrogen as infants are said to abound more in albumen and adults to be [illegible] “Iron zinc copper silver tonics & antispas. are useful” “Conium 2, 3, 4 grs with carb. fer. 10-20 grs” # “I have used with advantage mur. lime 3-4 drops increased to a tablespoonful & also mur. [illegible] 3-30 drops given in milk & water or in coffee. They are tonic & act on the lymph. & gland. syst.” Articles containing [illegible] In [anthelmint???] vesicular [illegible] F. idealis ([illegible]) (sea cabbage) has been given for worms and some families learn their children to cut it A mucilage may be made F [vesiculosis] [illegible] which with bran has constituted a popular poultice for scrofulous tumours When there is loss of tone & an ill conditioned discharge cantharides with opium is a valuable excitant Never continue any remedy after it debilitates by exciting disgust and nausea Mercurial plaister of the shops (gum ammoniac & blue ointment equal parts) has been much used especially for scrof. [swell.] of the joints In these [illegible] become extensively effective and become spongy A man at the westward was very celebrated for curing scrofula. He used wild violets but was not particular as to which species he used 163 blistering van Heuvel’s child a round of remedies had been tried [illegible] Occasional purging with calomel and rhubarb and ipecac in a pill will be useful Preparation of iron, carbonate of iron with conium etc. muriate of [illegible] 3 drops or 6 and barytes in [illegible] you give a teaspoonful iodine scrophularia mar. [Cistus] Canadensis uva ursi Mr Daggett Havanna Dublin Eliza Collis Vide p. 209 Iron no prep. perhaps are better than myrrh mixture or Jenkins’ pills (carb. per. [illegible] camph.) “Bark & quinine” Different preparations of [illegible] & barytes # Now superseded by iodine. I have seen more powerful affects produced by 4 dr. tinct. iod. persevered in a long “5 to 20 gtts within the year 2-3 gtts ter in die” Various vegetable articles I think very highly Rock rose or Cistus Can. (Helia [illegible] [pity] it is changed) Some years since a person went to Long Island to be cured of scrofula to a family famous for curing scrofula returned much benefitted should his remedies they [illegible] [illegible] & [illegible] always used than afterwards, when [illegible] [illegible] from Havan. neck filled up cured by [illegible] had been salivated W. I. without benefit Eliza Collis scrofulous cough much [illegible] cured by [cistis] vide p. 209. Scroph. maril. has been popular has been much used by empirics I have seen it sold at a great price brought from the west a very common plant It has been celebrated for accelerating parturition probably with out foundation The article has probably little or no power. Yet it is advantageous to know such articles in order to [illegible] [illegible] Two entirely different diseases but are classed together and may be treated together “H. externus is correctly named hydrocephalus” “No fever ordinarily attends. The disease consists in loss of town in the absorbents” Of late iodine has been recommended [illegible] two years since I was called to a patient with had enormously distended [illegible] [upon] gr. cal. & 2 drops tinct. iod. [illegible] recovered Tinct. canth. Face pale and bloated child sleepy and [illegible] I know one child who recovered, but at at the ages of 5 or 6 years died of H. internus. If the patient recovers he is more liable to the acute disease afterwards. Puncturing the membrane has been tried with success, and the application of bandages then supporting the child. It is said that puncturing of the pressure has [illegible] 164 Hydrocephalus Divided into two species externus and internus In H. externus the water is formed between the membranes of the brain (between the brain and its membranes?) In H. internus it is in the ventricles of the brain H. externus make its appearance at birth and is usually born with the child. # In its ordinary form it is fatal (It is almost always fatal when it makes its appearance immediately after birth and always so if born with the child) Stimulating and discutient applications to the head have been recommended. Epispastics are said to be serviceable. (Blisters have been found serviceable they should be kept up for a length of time) Mild mercurials cal. or blue pill & the muriate of lime or sometimes [illegible] pressure by bandaging . If the disease is accompanied by rickets the cold bath is indicated and has been found serviceable I have known one child recover from this disease and other who has been mending under medical treatment for 2 years past. I do not know whether it recovered # H. externus appears to be nearly allied to those watery tumours which affect the spine. In consequence of a partial opening of the sutures of the cranium, or the absence of a portion of one of the bones the dura mater and scalp are protruded by the pressure of the contained water & form a swelling on the outside of the head. Puncturing this tumour is suddenly fatal (is as fatal as the same operation performed on the tumor of the spine. Arachnoid inflammation, arachnitis, apoplexia hydrocephalica (Cullen) encephalitis phrenicula of Rush cephalitis profundu of Good We might multiply [illegible] but perhaps this is sufficient The disease different in different cases A great deal has been written and great deal of confusion exists “In this species of hydrocephalus the effusion of serum is into the ventricles of the brain. This serous effusion is the effect of the disease and not the disease itself & hence it may follow diseases of various kinds. I consider the name very improper” # “The vomiting if it cannot be ascribed to improper food in the stomach is an important symptom in the diagnosis” 165 Hydrocephalus Internus acutus Under this unfortunate name I propose to treat of all those cephalic diseases which are less violent in their action than phrenitis (or are less inflammatory). I shall principally confine myself to the disease as it appears in children “Symptoms different in different cases” The disease commences with the following symptoms (one form of the disease is well described by Dr Quin) vide [illegible] vol 2 p. 315 The patient is languid inactive and drowsy more or less feverish at times apparently free from any complaint (drowsy & peevish at intervals easy and apparently free from any complaint) The appetite is poor and irregular (week) & (Nausea &) in many cases vomiting # occurs once or twice a day. The skin “Exacerbation towards [illegible]” is generally hot and dry (towards evening) and if a perspiration occurs it is partial. Soon after these symptoms. The patient is troubled with a headach. The seat of the pain varies in different cases, sometimes it is confined to one side of the head (Soon after these symptoms commence the patient is affected with a sharp headach either in the fore part or crown) It is a common observation that the headache alternates with the affection of the stomach, the vomiting being less troublesome when the pain in the head is most violent. The pain occasionally attacks other parts of the body (& sometimes principally confined to the back of the neck and the space between the scapulae) At this period the patient is averse to the light, cries much & sleeps little While asleep the patient shows # “The tongue is commonly clean & in this respect this aff. differs from remittent bilious fever, in which the vomiting & febricula are attended with a yellow fur upon the tongue” One side of the face body one arm or one leg more affected or moved often is perhaps a severe a pathogen sump. as any other. This is an indication of paralysis I have known [illegible] patient recover from paralysis 166 signs of uneasiness grating grinding the teeth. starting and screaming in sleep as if terrified. The bowels are usually constipated though sometimes relaxed. The pulse in this early stage does not indicate much danger (These symptoms however are subject to great variations). These symptoms are succeeded by affections of the eyes. One eye is turned in ward to the nose its pupil is dilated The pupil contracted in this early & dilated in the latter stages. Sometimes both eyes at the same time are affected in this way both turned inwards & both pupils dilated. In this stage the vomiting becomes more constant and the headache more excruciating, the pulse is frequent and the breathing quick. # If these symptoms supervene to typhus fever, the pulse becomes more slow Exacerbations of fever take place towards evening. There is often a flush upon one cheek (flushing is usually confined to one cheek) Perspiration if it appears is usually confined to the head and chest. A discharge of blood from the nose at this time relieves the symptoms of fever (& removes the flush from the cheek) for a time & any favorable symptoms. Delirium often takes place at this time and is violent in proportion to the age of the patient All this time the disease is undergoing a change. As the disease advances the pulse becomes more slow and unequal & the patient becomes less sensible to (the pain in the head) his sufferings Lethargy succeeds the disturbed sleep and restlessness of the early part of the disease. The strabismus and dilatation of the pupils increase & the eye loses its sensibility Loss of vision (The patient after sleeps with one or both eyes half closed) The patient in this stage often takes medicine & # “Even in this stage patients have been cured by the strong impression on the system made by tartar em. pushed so far as to produce colic” vide infra Sometimes when hemiplegia takes place the disease puts on a chronic form In the 167 sometimes food will sometimes however he obstinately refuses to take any thing. The bowels for the most part continue costive. # To these symptoms succeed a quick small pulse (almost imperceptible) bad symptoms in the last stage sure forerunners of a speedy dissolution (a difficulty of breathing in many cases the flushing of the face is succeeded by extreme paleness sometimes in this stage petechial eruptions appear on various parts of the body & the patient dies in convulsions or sometimes a hemiplegia takes place two or three days before death The disease sometimes runs through its stage in 4 or 5 days at other times it requires as many weeks. The dilatation of the pupils in some cases does not take place until the last stages & perhaps sometimes not at all. In all cases the proper treatment should have been pursued before strabismus, blindness or coma takes place, because very little is to be done afterwards. A constant rolling of the head & moving one arm and one leg are among the most important early symptoms which indicate a dangerous affection of the brain) The disease sometimes puts on the form of an intermittent. When the disease has terminated in effusion the case is probably always fatal. much dissatisfaction after existed When an ordinary fever terminated in hydrocephalus thinking that the phys. was mistaken at first “I think this disease is rarely an idiopathic affection. It supervenes upon other diseases & generally depends on disease of the stomach & bowels” The disease when from ext. violence may exist without any [pathognomic] symptom 168 Causes external violence teething worms Other fevers forming a crisis by effusion into the ventricles of the brain. Typh. fev. & dysent. in children terminate in [illegible] I have known more than one instance in which it followed [illegible] of hip joiont This is very rarely an idiopathic affection unless it may be considered so when it arises from external violence Vide L. J Pringle on dis. of [illegible] When it does arise from external violence it rarely puts on the same symptoms or the same appearances after death All the diseases of children from infancy are liable to terminate by hydrocephalus & hence it is important to examine all the symptoms which may indicate a determination to the brain & check the tendency if possible Case A girl 14 years of age, had symptoms of affection of the brain from a fall upon the occiput she complained of pain in her head for two or three months before she died & occasionally had regular epileptic fits [illegible] [mouth] The pain the head was relieved by cupping and epispastics to the head, but she finally died in an epileptic fit On dissection the dura mater under the cranium, where the injury had been received was thickened and the vessels were injected with blood. The ventricles contained half a pint of water. Dropsy in the brain Yet the pat. had no dilatation of pupils etc. The dis. put on the appearance of epilepsy occurring once a month. More common in some families than in others 169 Causes. Hydrocephalus is a disease nearly allied to with scrofula & like that seems to run in families. Delicate children in whom the mental faculties are more early developed are more subject to it. Hence the common observation that the child is [illegible] forward that it will not live long I think persons of a scrofulous habit are more subject to this disease & that of the hip joint When there has been no local injury to the brain, the disease commences with affection of the bowels, or it is a sympathetic affection from disease of the bowels In the progress of bowel complaints in children, the [illegible] and the small veins become turgid. This enlargement of the vessels seems to invite the blood to that part. In consequence of this child may die with symptoms of hydrocephalus, from the turgescence of the vessels, without any effusion into the ventricles In typhus fever, in dysentery and in other bowel complaints of children it is not uncommon for children to die with symptoms of hydrocephalus It is a good symptom in hydro. to have a discharge from the [sch??der???] membrane 170 Diagnosis “In its early stage, this disease is scarcely to be distinguished from remitting fever When from the anxiety of relatives & of the physician, a diagnosis is eagerly desired, the following circumstances may perhaps assist in forming a judgment If there is occasional vomiting, with febricula the tongue at the same time remaining [illegible], there is reason to apprehend that the primary irritation has its seat in the brain and that it will prove a fatal case of hydrocephalus. But if along with the fever and vomiting the tongue is covered with a thick yellow fur, we may hope that the complaint is confined to the digestive organs and that the disease is nothing more than coler or remittent fever.” Ed.reviewer Diagnostic symptoms between idiopathic arachnitis or cerebral fever, and infantile remittent or fever from intestinal irritation choler In cerebral fever the abdomen is flattened, not tumefied but in intestinal fever it is tumefied. In idiopathic cerebral fever the secretions of saliva and that form the schneideran membrane are diminished. Unless complicated with aff. of muc. m. which is rare. In cerebral fever the tip and edges of the tongue are red In intestinal covered with a thick fur. In cerebral fever the pain in the head is severe and excruciating; in fever from intestinal irritation it is obtuse. # the sides of the head, back of the head on the forehead Perhaps a constant rolling of the head & movement of an arm & leg are among the most important symptoms Different opinion ben entertained about the nature of the disease Some have been so anxious about determining the exact nosological nature of it disease as to refrain from prescribing until the first stage has gone by. Prescribe for the symptoms at all events and make up your mind about the nature of the affection as fast as you can. Too much discrimination cannot be exercised & cultivated yet where we cannot determine the exact nature of the disease we had better treat the existing symptoms & the obvious indications # It varies in scrofulous constit. there is no such state It may approximate in some cases And I might cite the opinion of 20 others The [illegible] it is sometimes entonic & sometimes tonic. It more frequently [illegible] determined Why shd not fevers terminate in the brain as well as [illegible] 171 In intestinal fever the patient more frequently directs his hand to the nose & about the face in cerebral puts his hand to his head # In cerebral affections the head is hotter than the abdomen; but if the disease originates from the bowels the abdomen is the hottest. “There in a very few cases seen picking at the nose in cerebral fever but in general the rule holds good” “The state of the bowels is not pathognomic” Dr Beddoes thinks the disease belongs to inflammations & that at an early period he should be inclined to bleed as largely as in pneumonia # Dr Withering observes “in a great many cases if not in all, congestion or slight inflammation are the precursors of aqueous accumulation Dr Rush thinks that instead of being considered an idiopathic dropsy, it should be regarded only as an affect of primary inflammation or congestion of the brain “Dr Rush says” It appears that the disease in its first stage is the effect of causes which produce a less degree of that inflammation which constitutes phrenitis & that its second stage is a less degree of that effusion which produces serous apoplexy of the brain Dr Darwin supposes torpor or inactivity of the absorbent vessels of the brain to be the cause of H. internus Dr Whytt in his treatise on the disease observes that this and every kind of dropsy depends upon the fact that more fluids are thrown out by the exhalants than [illegible] the absorbents take up I chiefly depend upon calomel for a cure if it cause too much evacuation check it with opium There is no evacuation from the brain therefore the disease must be overcome by altering the secretions counterirritation etc. Bleeding with leeches from the temples seems to translate to the surface and give relief vide John Hunter. Case young man apparently as desperate a cure as ever I saw not scrofulous we concluded to try tart. emet. gave it without much weight in about 8 or 16 hours he complained of violent pain ion the bowels and all the symptoms of the head were relieved [illegible] “Irritant to the schneiderian membrane in the last stages are recommended by Dr Malachi Foote of N. Y. in the Med. Rep. for about 1810. Turpenth min. 1 gr. with liquorice 20 grs [apreynum] [myrici] ipecac etc. are the best [stermentatories]” 172 Treatment Evacuants Bleeding general & local cathartics calomel and jalap gamboge Counterirritation local bleeding cupping epispastics behind the ears and to the whole surface of the head Salivation should be induced but cal. often relieves without altering the secretions There has been a difference of opinion as to the application of epispastics to the head. If venesection be indicated they should not be applied until after bleeding. I prefer cupping and blisters to the back of the neck and behind the ears I think some advantage may be derived from applying to the spine ol. orig. ol. capsc. etc. Where considerable entonic action has existed I have cured this disease by giving tartar emetic until colic was produced. give perhaps a grain & continue its exhibition until the symptoms abate # “gr doses every 2 or 3 hours” Sneiderian membrane dry snuff malachi root Irritants applied to the schneiderian membrane have cured the disease in its last stages Rx 1 part turpenth mineral & 10 parts powdered liquorice for a [ster??tatory] Green tea is sometimes given In the progress of the bowel complaints of children the sinuses may become enlarged & a determination of blood [illegible] to the brain and produce symptoms of hydr. I have known pat. apparently die of hyd. & yet upon dissection no water be found in the [ventricles] in this case some say that the water was absorbed in death this is entirely improbably. Certainly many of the symptoms of hydr may be prod. by other causes e.g. excessive doses of narcotics is stramonium belladonna It shd be remarked that many cases supposed to terminate in hydr. in cases of [termination] in volvulus “All the diseases of children are peculiarly liable to terminate in hydrocephalus. Hence the importance of caution on the part of the physician. He should examine all the symptoms to check the first beginning of determination of diseases action to the head V.S. keep the bowels open blisters behind the ears cupping leeches” 173 Hydrocephalus from bowel complaints If in the progress of any of the bowel complaints of children morbid action should be determined to the brain, Epispastics should be applied behind the ears and irritants to the feet Cathartics are useful to obviate this determination. # In some cases perhaps the determination [marise] from nervous irritation. In such cases the tepid bath gives relief “Strong green tea” Some physicians of respectability have in formed one that they have used digitalis in hydrocephalus with very good success. I have not used it myself but should consider more adapted for that form of the disease which arises from irritation, than any other Hydrocephalus from disease of hip joint. Child of Ezra Hotchkiss child of Horace Edwards. “I have known hyd. alternate with disease of hip joint Case Narcotics etc. till suppuration” Afterwards died of hydrocephalus # I have cured a patient by giving him calomel and lemon juice in sufficient quantity to move the bowels. It increases the secretions and improves the tone of the bowels “I have seen a case in which the child fell 8 or 10 feet upon a pavement & broke his skull like a squash shell yet he recovered in 2 weeks and did well. When the fracture is so extensive there is less danger of compression of the brain” The same case? Hyd. from injury by a fall is not common in young children the sutures are not firmly closed (the bones are softer & more yielding)( # He had other severe wounds as a compd fract. of the radius yet he never suffered his head 174 When the disease is produced by violence Depressions of the cranium in children from blows or falls are not of course fatal though dangerous. A child four months old fell head foremost upon the hearth striking upon the vertex. The head was much flattened & the parietal bones bulged out on each side. The child did not suffer much from the injury. The bowels were kept open by mild mercurial purgatives. In these the head assumed very nearly its natural shape. A boy of eight years fell six or eight feet and struck his head against a stone A depression of the cranium was made larger than the bowl of a spoon. He suffered very little inconvenience from the injury # There is less danger when the skull is so much fractured as not to cause pressure upon the brain If a child has received a fall we may apprehend danger from the following circumstances. If the fall has been upon the occiput the brain is more commonly injured than if the face is upon the os frontis. If the child vomits after the fall and is very sleepy there is danger that the brain will suffer. Treatment If the child vomits or is comatose after the fall upon the head and there is no wound that bleeds the patient should lose blood and take a dose of calomel, one or both according to the urgency of the symptoms & the death of the patient. All the exciting causes of fever should be avoided and the patient kept as quiet as maybe. The symptoms should be carefully watched and if at anytime there should appear to be a tendency to an affectation # for local bleeding is as important a general bleeding “[illegible] all causes of irritation, as light noise heat, food. Keep the pat. perfectly quiet” “Apply an epispastic behind the ear, or better upon the injured part.” “Blisters are very useful” “Use counterirritation & the tepid bath” # In torpor of the br. [illegible] al. can excite the latter may excite the former and excessive action in the former may be translated by it act on the latter “Give strong cath. cal. gamboge jalap etc.” “Afterwards give cal. in small doses as an alterative If it causes too much evacuation check it with opium” “In N. Haven we have followed Abernethy’s plan of treating infl. of brain for 40 years” 175 of the brain the patient ought to be bled & leeches or cupped. # The bowels should be opened with calomel and small doses of the same remedy frequently given as an alterative After depletion epispastics may be applied behind the ears and upon the part of the head where the injury was received. There is no outlet to the brain & consequently more evacuants are needed than in most diseases Frequent cathartics are useful as evacuants and also to translate action from the brain # When effusion has taken place the case is probably always fatal Yet I have had a pat. with dil. of pupils, who cont. so & paralytic for months & finally recover Vide p. 200 The treatment consists of local applications A variety are used One of the best is [illegible] zii alc. zi An equally good or a better application is seneka oil but the smell is disagreeable. Cold water is applied but though it relieves the pain and the insupportable itching it is doubtful whether it is of any permanent benefit Basilicon [illegible] [illegible] absorbents to ulcers 176 Chilblains Pernio This is a local affection to which children and old people are most subject. Some are much more liable than others. [illegible] [illegible] more liable. The parts affected are the toes heels fingers, hands face, ears and with ladies who wear short sleeves in winter. It is caused by exposure to extreme cold & to cold & damp air & on the feet, more especially by walking through melting snow. It is most common in the early part of winter This affection should be prevented by avoiding an exposure of the parts to the air, by keeping the hands warm with soft leather gloves & by keeping the feet warm with stockings and shoes The skin of the part affected becomes tumefied and hard & of a deep purple colour, there is a pungent pain in the part accompanied with an insupportable itching; & these are often so great as to prevent the patient from sleeping. If the disease advances, the cuticle breaks and discharges a thin fluid. Sometimes a deep ulcer is formed The treatment for the first stage should consist of stimulating application as if for a burn. I prefer oil of origanum alcohol & seneca oil are good applications. Spirits of turpentine will ordinarily do well, though in some idiosyncrasies it acts as a poison. Cologne water may be applied or alcohol two parts with one of ol. orig. # For the ulcers you may use the oxygenated ointment ointment of red precip. citrine oint. # or apply a plaister Dyachylon or Noel’s Not being able to have any fire on board for some days [illegible] to pain of a neuralgic kind as [illegible] were a toothache One of the best applications is a cataplasm of stramonium seeds give internally opium narcotics & stimulants Apply [illegible] & narcotics Followed by no infl. to supp. etc. 177 Painful affection from cold We sometimes meet with a painful affection of the feet without discoloration, or any other visible mark, which has been brought on by long exposure to cold without freezing. Sailors coming upon our coast from the I. in winter, from a warmer climate are liable to it. The affection may be a very painful one and give great uneasiness both night and day It is relieved by the external application of stramonium & epispastics or rubefacients, and fomentations Cathartics and opium may also be given internally. Singular effect of cold in Wm Daggett Burns are dangerous in proportion to their extent [illegible] young physicians are called to prescribe for burns it is important for them to treat them in the best manner About 30 years ago a great controversy existed in England between those who advocated [stimulating] In recent cases stimulating or exciting applications are the best provided the burn is not very deep. About 30 years since spts turp. were much used. It in some case and these are not very rare Case myself [water] boiled over into my shoe I immediately poured spts tupr upon the stocking then took off the stocking applied a cloth dipped in spts turp. put on a dry stock. & boot rode out of town and suffered My father was a man of florid complex. & thin skin He was burned in n a similar manner Ol. orig. Linseed oil is smooth mixed with limewater alcohol or proof spts good when the skin is [illegible] off Others use camphor Others stramonium in ointment contain what [illegible] when the article s off Carrot poultices etc. exclude the air Cotton does well except when the cuticle is off if it is used then you had better smear it with oil 178 Burns This subject belongs more particularly to surgery, yet as burns occur most frequently among children, and you may be suddenly called in on such an occasion, when it is important that a remedy be speedily applied. I have thought proper to make some remarks on the subject. For the treatment of burns very different modes have been recommended. A long controversy was carried on in one of the English journals with respect to the phlogistic or antiphlogistic treatment, one party being in favour of cold applications in cold water and the other of stimulating ones as spirits of turpentine The truth seems to be that in adults where the injury is not extensive and the powers of life are strong cold applications do well, but they are dangerous for children especially if the injury is extensive. Burns upon the abdomen will not admit of cold application even in adults It is necessary that reaction take place If there be no reaction of the system, no pain, no inflammation the child dies. The cause of its death is the irritation of the nervous system, extended to the stomach, & hence the death is preceded by cold extremities and vomiting Where cold application are proper such applications may be made as scraped potatoes, cloths wrung out in cold water etc. But if it is necessary to produce reaction and inflammatory action stimulating remedies must be used. And we know from experience that these remedies do effect a speedier cure Cold applications may do well if immediately e.g. dip a burnt arm immediately into cold water. But stim. app. are better. I have tried both. Cold applic. very dang. in extensive burns of children Case scarped potatoes no infl. livid appearance of the burn extrem. cold [illegible] death In such cases apply stim. app. & give ether, elix. [illegible] etc. etc. In these cases the child dies of irritation not infl. It seems to be necessary for a regular [course] of continuity of action in infl. & suppuration The best and mildest application as has been proved by experience is petroleum or seneca oil In one case I tried the experiment of applying seneca oil upon one hand & ol. orig. upon another (both being known alike) one hand was easy the whole night the other painful (the burn was a very extensive from the clothes taking fire) In the suppurating stage use 1 part seneca oil & 3 parts cerate These cases are very troublesome to treat In the above case the system was exhausted by the extensive suppuration the bowels had to be kept open & large quantities of opium to be given. I gave columbo bark and various tonics and aromatics Turner’s cerate is a good application chalk may be sprinkled over it In the progress of the suppuration a pale flabby fungus almost like a blister and is difficult to manage I have applied a sol. nit. sil. also nit. sil. & laudanum [illegible] cop. sometimes after these I have succeeded with ac. op. in ointment green basilicon i.e. verdigris ground fine & mixed with basilicon But if you apply only applications after these caustics 179 The reason is that we apply to the part a stimulus less powerful than that which produced the injury and thus render the diminution of the excessive excitement gradual. On this principle holding the injured part near the fire is beneficial Another important indication in the treatment of burns is to exclude the irritation of the external air Hence the popularity of some applications as cotton. sweet oil etc. 1st Of stimulating applications. Spirits of turpentine will answer for a robust and healthy person but not for a slender & feeble one; and it must be remembered that from a peculiar idiosyncracy it is a poison to some persons. In general spirits of turpentine is liable to cause irritation and may be suspended by better articles. Being burnt myself a complete cure was effected without the least appearance of inflammation, by this article but in the case of my father such violent irritation was produced as to oblige him to desist from applying it A common remedy in this town is the oil of the origanum majorarum called burn oil mix ol. orig. zii with ol. oliv. zi or mix it with alcohol or cerate. Cloths may be dipped in the diluted oil and kept constantly applied Of late years I have used seneca oil and prefer it to either of the two already mentioned. In several cases I have tried both this and the ol orig. & found that the seneca oil relieved more speedily & with less irritation. I usually apply the seneca oil & the fungus [illegible] Apply rather chalk or fine alabaster or scorched flour The sooner you apply stim. appl. the better ol. turp. produces [illegible] etc. seneca oil does not Case a woman thief etc. etc. we rolled immediately in the snow was thrown by it into a state of syncope life almost extinguished was burnt universally except on the legs covered by the stockings was wrapped in sheets dipped in a mixture of ol. orig. & spirits 180 then cover the part with cotton to exclude the air. I let them remain till suppuration takes place, particularly if the skin is broken. When suppuration takes place, apply a poultice to the loose dressings and then apply simple cerate or a cerate made by melting together beeswax and lard and stirring in seneca oil while the mixture is cooling This last is an admirable application for burns Dr [Mons??] said he knew none so wild. It protects the raw surface from the cold air and keeps in the animal heat In the latter stages of the cure, the oxygenated ointment will be a soothing application A popular remedy is stramonium, used in the form of a plaister of the seeds or leaves. It answers well and I have known no ill consequences to happen from its use though it is said that in extensive burns it is dangerous Cotton is a popular application, used by itself For slight burns it will answer but if they are so extensive that suppuration is to take place, it should not be applied in this way Other remedies that are useful upon the principle of excluding the air, are the oils as sweet oil & lamp oil. Linseed oil mixed with one third part lime water, is especially recommended When suppuration takes place and the cicatrices do not form well, oily application should be laid aside and if there is considerable discharge apply absorbents, as plaister of paris, chalk & chalk & cerate i.e. apply chalk first & cover with cerate. Note from Dr Woodward of Wethersfield extracted from Dr A. Talcotts notes “Apply immediately spts turpentine to the inflamed parts and cerate of limewater & linseed oil equal parts on cotton to the vesications 2nd If pain & irritation ointment of stramonium 3d To prevent fungus Rx white lead a teaspoonful lard 2 tablespnfl. ft. ung. Orgrate or chalk and apply simple cerate over it. I have seen a metastasis at the end of a week to the bowels with diarrhoea & tumefaction or the bronchia with croup Treat with opium & bark Dr S. B. Woodward” N. B. I extracted this principally on account of the definite direction about the difficult treatment required according on the burned part is vesicated or not a point on which the above notes of DR Ives do not seem to be sufficiently precise 181 Should there be a fetid discharge from the burn, it may be remedied by pulverised charcoal. Sometimes the ulcers are very difficult to heal and repeatedly break out afresh A fungus may arise upon the part if so it should be touched with caustic. The eager of the ulcers may be touched with sulph. copper or nit. sil. chalk then applied and the whole covered with cerate. If the burn is on parts liable to unite in healing, as between the fingers and toes, care should be taken to prevent the union. A bad cicatrix is often formed which it is difficult to prevent or cure. Internal Treat When the constitution has received a severe shock and the extremities become cold and the powers of life being to fail, the system must be supported by stimulants & cordials & the excessive irritation relieved by opiates. Laudanum ammonia, spirits, alcohol ether are all good. To a child from 5 to 10 years old 15 drops of laudanum may be given; warm-applications may be made & warm aromatics drinks as ginger tea & mint water administered. Elixir paregoric is one of the best preparations of opium in such cases In a case in which a large quantity of sulphuric acid had been drunk by a boy who immediately afterward, ran to a brook and drank of the water. I merely give mild mucilaginous drinks & the patient being of a strong constitution recovered 182 Croup from p. 138 In what may seem to be the second type of patient may go off suddenly. If he throw his head back in order to enlarge the chest it is a bad sign I have found the treat. by tart. ant. so infallible in the first stage & in general so useful that I have not been tempted to desert it. If I am called rather late and find ext. ant. acting locally upon the stomach, I seldom succeed in curing the patient. Other emetics may be used when the excitability is worm out for [illegible] Calomel is proper in the latter stages, [illegible] the disease is partly broke up by antimony If the first stage is not interrupted [illegible] the child may be playful between the paroxysms and though the pulse is not affected, yet the second will surely come on In the second stage bleeding is to be first resorted to in order to prepare for emetics bleed even to fainting conjoining the warm bath for the same etc. Exciting and irritability [illegible] in this second stage do mischief. I have seen sanguinaria do much mischief. Even after bleeding purges is not advisable for as has been remarked there is a constant tendency in the system to the return of this inflammatory symptom Cal. may be given though if it act by the bowels it will be useless. I have seen bleeding and the vapour bath palliate the symptoms. Scarcely ever will the patient recover 183 Croup In the latter part of the last stage the child throws its head back. This is a dangerous symptom. Now the patient goes into the last or suffocating stage. The patient lies on its back struggles violently for breath countenance livid appears apoplectic and often goes into convulsions and in these convulsions sometimes dies Sometimes in this stage you may hear a flapping of the false membrane. This is sometimes thrown up and great relief is afforded and the friends think that all is over. Soon however in most even of those cases a membrane is formed lower down & the patient ultimately dies In this stage the metallic emetics have in a few cases succeeded The sulph. cupri & the sulph. zinc have each cured Cal. is recommended & may be used The cold both has been recommended It may be tried as a dernier resort. In the second stage after bleeding blisters shd be applied over the whole neck & chest Dr Hosack recommends bleeding from the back of the hand immersed in warm water After bleeding has succeeded in subduing the symptoms cal. & the warm bath shd be used 184 Croup This disease has been divided into acute & chronic but without much propriety Sometimes it continues for some time. I have known one case which continued 3 or 4 weeks In some seasons a different mode o f practice is better. I have known seasons in which cath. & diaph. were the best treatment Although for the first 15 years of my practice I considered nothing more unfortunate than to find the child under the operation of a cathartic. In these cases, it was the form in which the duodenum is also affected in a similar manner Case Wallingford [emet.] failed & cal. & diaph [illegible] Others that season occurred which required the same treatment Bronchotomy has been recommended I have seen it performed but never with success It has sometimes succeeded But in the cases which I saw the membrane form lower down, and the patient die 186 You will see by looking into the throat the tonsils perhaps red & the epiglottis certainly inflamed 187 Angina Laryngia Another form of the croup has been called angina laryngia [illegible] the croup you can see nothing by looking into the throat In this the epiglottis & the [illegible] glottidis are affected From the larynx being affected, the actions & more spasmodic Frequently comes on while eating Case of my child While apparently well was taken while eating with the peculiar croup & respiration of croup & became alarmed & treated This is the form which attacks old people probably Geo. Wash. died of it Case The first time I saw this disease the pat. had had pneumonia & may nearly recover when he went into the cold open air without stockings. I was informed that he was taken with difficult respir. & without seeing him prescribed seneka injurious ultimately refused to swallow anything as the act brought on a spasm I tried bleeding, blisters, vapour & after awhile persuaded him to swallow when I gave him 4 gr. tart. ant. in a cable spoonful of water 188 Angina Laryngea The dis. is brought on by eating And if you examine the throat you will see a redness perhaps upon the tonsils, and will certainly see the epiglottis inflamed Bronchotomy promises more in this form of croup Readily distinguished for the other by difficult deglutition paroxysms being brought on by an attempt to swallow This firm It is not of much consequence to distinguish the forms except that laryngea is more rapid And you must avoid acrids in this form as they irritate the fauces & produce spasmodic action For the spasmodic symptoms give in the latter stages of it asafoetida which also acts upon the secretion tinct. ant. & opium It must be remembered that this disease cannot be cured by bleeding alone. It is too far out of the circulation. But by reducing the system very 189 Croup concluded When croup follows other diseases it is more rapid and dangerous they are very apt to die particularly when following ulcerated sore throat You may treat by emetics blisters metallic emetics etc. but you have not so much strength left in the system to act upon In the latter stage where we wish to throw up the membrane the stomach may lose its excitability to a particular emetic then you are to change the em. I have succeeded in throwing up Upon dissection a membrane is found formed But sometimes it is wanting and in A laryngea then probably is not [time] for a membrane to form Vide p. 211 low and suspending the functions you may change the secretions perhaps 190 191 Scarlet Fever Withering in his first edition separated ulcerated sore throat from scarlet fever. In the second he changed his opinion Where there is much heat and fullness of the pulse I would much prefer a strong dose of cal. followed by antimonials [to] commencing with emetics Or is Dr Rush & the elder DR Barton thought best turpeth mineral Epispastics are to be used with caution & adopted this rule viz to apply them where there is much tumefaction [illegible] & enlargement approaching the quinsy. Scarlet fever after resembling quinsy and is with difficulty distinguished except from the previous affections of the family and neighborhood Mineral acids have been considered specifics Chlorine was much used in this town in [1801] etc. as a fumigator. You may give it internally with advantage A great variety of gargles are used generally stimulating ones are better as those of capsicum (with salt say in cider water) In some cases capsicum does not do well If the patient is too weak to gargle use a syringe 192 Scarlet Fever Chlorate of potash was used with advantage to quiet the stomach. It allayed irritation etc. Ammonia and amm. with camphor & gum arabic In the progress of the disease mineral emetics, as sulphate zinc will be useful to excite the system acting speedily they do not exhaust sul. zinc 5 to 20 grs mosely’s solution was the form most used Sulph. copper 2 to 5 gr. also as an emetic Acetate of copper was formerly kept as a nostrum in some families ½ to 1 t. sp. of sat. sol. of common verdigris 2 to 3 gr. In some cases and seasons cath. are required. I have treated children without a single cath & yet in the same family I have given ant. followed by cal. & worked off by salts and senna If a diarrhoea occurs early it must be attended to white decoction 193 Scarlet Fever Dr With. lays great [illegible] upon diuretics particularly senega giving it throughout the disease. In moderate fevers diuretics eliminate morbid action will Serpentaria may be given freely throughout the disease adding bark alcohol ether or wine Diuretics & diaphoretics Irritable state of the stomach is to be counteracted by irritants by aromatics white decoction etc. etc. a little alcohol upon the fauces voiding a great bulk of liquid Case of a boy in delirium his father was forcing down articles which he was puking up I put into his mouth spoon dipped in brandy 20 or 30 drops his eyes opened immediately said it was good continued it in tspfl doses through the night saved his life Scarlet fever occasionally passed by insensible gradations into quinsy and is of an inflammatory character. No one character will distinguish them No one mode of practice will answer in all cases though if any indiscriminate mode of practice is to be followed that by emetics and stimulants will be best In many cases no evacuations at all are to be used if this you must judge by the symptoms In the same family I have lately treated one or two patients with antimonial and nitre and another who had been worn down by fatigue and watching with feeble pulses vomiting coldness etc. was treated by external heat, brandy in moderate 194 Scarlet Fever quantities, counterirritants spiced tea etc. to stop the vomiting # (One of the best articles in fevers of a low grade is spiced tea or hot spiced wine or brandy. The strength is apt to give out first, and an excitement kept up in the mucous membrane of the stomach will have a beneficial effect) # The first patients in this family I had evacuated freely both by vom. & purging etc. while this patient had no evacuation goodness & was supported throughout the whole progress of the disease After I had seen the disease in 3 or 4 epidemics I thought I had seen the disease in all its forms but I found oftenwards that I met with different forms still Not only different epidemics differ, but different cases during the same epidemic may require widely different treatment In the malignant epidemic of ’94 I was informed by some physicians that they met with cases in which there was increased action though the many cases of the epidemic ran rapidly in the [illegible] gangrenous state In 1803 we generally gave emetics It is said that in the malignant form the eruption is a bad symptom. I do not think so. I think it better for a general eruption to come out the action is less unequal than if a scanty or no eruption appears I hesitated in 1803 much about the application of blisters & I finally found that the rule was a safe and beneficial one to apply them where there was swelling of the tonsils In this epidemic I gave bark, the mineral acids, alcohol, wine, and (for the first time) tinct. canth Tinct. cant. [illegible] zi to pt. give 20 gtts once in 2 hours ½ as much to a child 195 In many cases [illegible] requires to be qualified & corrected by serpentaria or carb. amm. If wine injures the stomach and [illegible] too locally continue carb. amm. which will render it diffusible with white vinegar will have somewhat of an effervescing mixture Use also effervescing mixtures, as soda water, with brandy or ether, or aromatics tincture. It is no objection that you thus combine stimulants and refrigerants, for you thus get diffusible action and obviate unequal excitement. The min. acids may be given in form of punch The sugar will be grateful & useful A diarrhoea is apt to take place in the commencement of the disease. Use white decoction laudanum & injections of starch & laudanum RX starch 3 bal. sp. SS. 30 gtts to 2 t.sp. Pay great attention to cleanliness of the patient Where there is fainting apply ammonia and ether & spirits at the nostrils keep them applied to the nostrils to prevent fainting, I have never known any injury done by over excitement by these articles thus applied Capsicum is used in tropical [illegible] in very strong decoction. Salts and vinegar has been much used as an antiseptic gargle? For the diarrhoea use tonics, bark, contrayerva has been though valuable. Avoid injuring the stomach by distention 196 A variety of garbles (or injections by a small syringe) are used. [illegible] rosemary has been thought a specific & carried hundreds of miles into the country Use others when pat. is disgusted with one # Sulph. cop. ac. cop. nit. sil. ([touched]) apply these with a swab What is called the leathery inflammation is sometimes met with. in which the skin dies at first and afterwards comes off & then a discharge follows. This affection sometimes extends down the throat. In such cases apply blisters to the sternum Touch the part with nit. sil. in such cases. IN one of these the blister on the sternum produced an ulcer which was 3 mo. in healing and in another though the affection with throat was relieved the ulcer for the blister destroyed the little patient # [illegible] oak bark etc. pomegranate combine brandy aromatics etc. It might to be remembered that in the latter stages of ulcerated sore throat where there is an accumulation of [many] a phagedenic ulcer, emetics of sulph. zinc give tone and excite action also when Acetate copper in the latter stages used in an emetic as a tonic or locally applied as a caustic When the stomach fails in the latter stages we give capsicum in pill or strong infusion (2 tab. sp. to the pt makes a strong infusion give to an adult a tablespoonful also acrid oils There seems to be an erythematic infl. of the mucous 197 membrane of the stomach hence acrids are indicated to excite action Bark jacket also it seems to have some effect In the latter stages also a cath. will frequently be beneficial an accumulation of feces may exist given mild cath. as castor oil or perhaps a dose of cal. an emetic also may be needed One thing to be guarded against in young children is the supervention of dropsy In 1803 I had 3 cases all the writers considered the disease as one of weak [illegible] action and requiring tonics bark etc. Not successful Bark does not generally do well when there is unequal action I have known in such cases the brain & nervous system apparently much affected I have given in such cases digitalis and cantharides to produce as new excitement and ally this irritation in the nervous system Case related patient very low from a disease digitalis was given and elaterium being advised was given when the patient died upon the second evacuation In general treat these cases with diuretics a moderate use of cath. narcotics & remedies etc. Digitalis is the best narcotic but be cautious giving it to children In ordinary cases of such dropsy a cath. will remove it and frictions & exercise in the open air. Various articles are popular as ol. [mor] [199] [illegible] ol. gaultheria various irritants etc. and to encourage the attendants to persevere in rubbing you may suffer friction to be made with these mere dry friction though probably just as good does not seem to them like giving medicine Various astringents may be 200 Hydrocephalus The management of the pat. is equally important with the medication avoiding in proper diet alternatives of temperature, and all debilitating irritating and exciting agents all the exciting causes of disaster. Sometimes a patient may (after a fall perhaps) continue one two or 3 years not entirely [illegible] and yet not quite sick and finally die of eff. of the brain Sometimes in strumous habits canth. internally may be advantageous Blisters translate action The applications of remedies to the Schneiderian has been thoroughly treated by Dr Malachi [Foot] in the N.Y. Rep. about 20 years ago. The subject has not bee sufficiently attended to Give in the way turpenth wine (mixed with liquorice) verat. vir. apreyn. [illegible] myrica cerifera etc. If a discharge can be excited relief is afforded Salivation can rarely be produced in children In some cases where there is paralysis the acrids and some of the narcotics as strychnos Blisters are applied by some to extreme parts of the body I sometimes change the place of the blister to the back of the neck etc. But the back of 201 ears is more efficacious. It seems to have a grater affect upon the constitution to excite a discharge from this part If the symptoms indicate bleeding bleed leech also. If there is much infl. about the mouth scarify the gums as a depleting measure “In grade of action the fever of hydroceph may vary from high entonic inflammation or phrenitis to low strumous fever. If the action is too high or too low counterirritation will fall in with the morbid action We must first bring it to the “blistering point” (Rush) “Blisters to the head are thought by some to be dangerous and the ears or neck preferred” “In irritable cases and scrofulous habits, strong cathartics are hurtful. Give blue pill especially when the bowels are primarily affected. But in entonic phrenetic fever, use the drastic cath. & tart. ant. ut supra after depletion” “Scrophulous predisposed mesenteria glands generally affected the fever analogous to hectic never entonic pulse soft, frequent, quick I have tinct. cantharides with advantage in this variety” [204] Volvulus continued from p. 89:a:1/2 “Cases I was called to a child 2 years old which had symptoms of irritation and was obstinately constipated It had been carried on the belly upon the shoulders of another person Gave a cathartic Ordered an injection but the attendant said it would not [illegible] The cathartic was thrown up patient died Upon examination after death no color could be found. In the upper [illegible] rectum there was a tumor which seemed of solid flesh as large as the doubled fist inflamed. The color had been completely removed from its place” “I was called to another family where the children had died when 5 or 6 months old as was supposed of an affection of the brain. This child appeared well when born but was very costive etc. Upon p.m. [illegible] 2 inches of the small intestine were found contracted to the size of a goose quill the coats were thickened & the course the cavity must have been extremely small This contraction undoubtedly existed at birth. This contracted part was received into the part below it, and no [illegible] could have availed” from p. 99 ½ “In another family they had lost all their children at about such an age. They supposed the disease to be hydrocephalus. The older physicians called it so. I told them I could not tell what the disease was but it was not hydrocephalus I had then seen no case of volvulus. There were strong 205 marks of irritation the face was pale and much distress was depicted with countenance the head was rolled back and hands tossed violently. There was vomiting and tenesmus and a discharge of mucus streaked with blood Cathartics had been given under the impression that the disease was an affection of the head The cathartics aggravated the disease which ran a rapid course and the child died. The small intestine was found received into itself and its cavity obliterated. This obliteration of the cavity would not of itself cause death; for a patient may continue several days with perfect torpor of the bowel. It is the irritation as in cholera morbus which is the immediate cause of death which [illegible] death usually occurs within 24 or 36 hours” “Called to a child one year old constant vomiting stool, mucus streaked with blood Directed mucilaginous injections & fomentations combined with opium Gave opium freely internally 10-15 minims to allay vomiting. The symptoms subsided gradually & in 3 or 4 days the feces passed off without any cathartic” “Was called to an Academical student had given cathartics and they did no good. Called in older physicians. They were in doubt respecting the case and advised not to do any thing as we might do hurt. As I was sitting by his side I heard a motion in his bowels. I noticed that it passed down to a certain point and then stopped. Upon examination I could distinctly feel the involution. I tried injections and some [illegible] of them would stay. Ordered a spermacetic candle with opium upon its extremity to be passed up the rectum and allowed to remain. It was s 206 passed in to the length of 10 inches. The opium allayed irritation and the application by repetition replaced the part & the patient recovered another case cured by a bougie” “Opium by taking off the spasm and restoring the natural function of the bowels may be said to act as a cathartic just as in spasmodic colic” From p. 56 “I have given when I could obtain it, the [resin] of Mandrake podophyllum peltatum It operates kindly, and more certainly than any other article. If the western gentlemen who have so much mandrake and whiskey, would furnish a supply. I think it [will] supersede every other article” “If there is torpor & a stuffing or infarction of the bowels we must use injections to assist cathartics repeating them every 2 or 3 hours. If other cathartics do not operate give castor oil which will promote their operation” “The particular kind of injection is not important and may be left to parents Thoroughwort, camomile, mayweed catnip, dandelion, weak soap suds salt & water a tablespoonful to ½ pint water 207 Continued from p. 57 “The stools resemble meconium. In the progress of the disease they exhibit small pieces of a membrane of a dark green colours, about the size of the petals of peach blossoms floating in a dark green fluid. The membrane of coagulable lymph, resembles that formed in angina trachealis and sometimes as in that disease it is formed in such quantities as to cause obstructions Still in this case it may not destroy life the action of this part not being so immediately essential to life. Stools of this kind sometimes attend the bilious colic of adults. They are an indication that farther evacuation is needed Continue the calomel or combine it with magnesia or soluble tartar, or phosphate of soda or other neutral salts 208 Infantile remittent continued from p. 60 “Cases A child had violent fever gave calomel & cathartics warm bath symptoms abated. In 2 or 3 weeks the regular symptoms of hydrocephalus appeared; & the patient seised in the greatest danger. In a short time these symptoms were relieved by a violent and dangerous attack of thrush The patient was very much exhausted lay several days very low gradually emerged and after a long course recovered. “Case of a small little boy 5 or 6 years of age After 5 or 6 days head affected & became maniacal very irritable and cross swore profanely would bite and strike all who came near him. If any thing was attempted to be administered he would shut his mouth. If his mouth was pried open he would close his throat with his tongue Advised his parents not to trouble him nor notice him to pass by him with drink roasted apples etc. but not to offer him any thing. The first day to he took nothing second day took roasted apples etc. readily but ate too much mania returned, but soon went off & patient recovered” “In one case the pat. took nothing for a length of time. Recovered by use of [even ato] & external applications as aloetic plaisters to the bowels etc.” Scrofula continued from p. 163. “Scrofulous swellings are very difficult to excite to suppuration I have however then poulticed without effect for 2 or 4 months Of late I have disused poultices & have applied blisters as soon as may be to excite invigorate the absorbents and act as discutients. They do not disturb the system. If there is suppuration the relaxed state requires stimulating applications lunar caustic vegetable astringents etc.” “Case of a young act 18 with bad cough swelled neck scrofulous temperament Gave laxatives blue pill afterwards rub & spec. Then gave decoction of [cistus] [canadensis] for several weeks and pat. recovered “ A physician (Smith) on Long Island (from an old recipe) has acquired reputation by the use of cistus canadensis combined with uva ursi at the same time enjoining a strict & spare diet as in dyspepsia” “I have given with cist. canat. 1/8 gr. corr. sub. & also decoct. scroph. maril. which is thought by the vulgar to be a specific It has been sold as a nostrum to facilitate parturition called nerve root.) I think it useful in scrofula” “I have known the comptonia [illegible] folia given internally. It is tonic & has balsamic rpoperties” “The remedies particularly indicated are tonics & deobstruents such as will not produce congestion such as uva ursi cistus scrophuloria contrayerva agrimonia (entire plant or root angostura etc.” Sea bathing is recommended, but if the lungs are affected, it will not be advantageous. A sea voyage to the eastward has been of service the constant motion of the vessel stimulating all the vital organs to healthy action The change of air is beneficial & at a distance from the shore there is no danger of taking cold In chronic complaints attended with a want of vital energy I direct a voyage to the east rather than to the south Croup continued from p. 189 “Vapour bath Inhalation of warm water in a [pour] blow a current of air through hot water upon the pate & by means of a coffee pot with two spouts” “Tobacco or snuff applied to the patient” “Croup is an epidemic disease & of course it will vary at the different periods of its appearance We must take into account the prevailing diathesis I have described the disease as it has usually occurred in my practice” “The proxim. cause of the dis. is a peculiar morbid action translated to the traches for the disease arises from general causes acting on the system. In catarrh diseased action is seated primarily with mucous membrane. The exciting causes of croup act on the surface and with different diathesis the same crises might produce pneumonia, dysentery enteritis or cephalitis “Disease determines to the weaker part as the rod attracts lightning” Rush Water & snow cold damp air a [illegible] & low situation sudden changes as when the wind blows from Canada or the gulf stream are the exciting causes “In the treatment sanguinaria, if given early in strong decoction very freely, so that enough of it shall be given & still it vomits or relieves the symptoms, in very efficient practice adopted by Drs Jared Potter & Kirtland “But if inflammation has taken place & the second stage has arrived seneca and sanguinaria are both too stimulating and I have seen them do hurt sanguinaria is less stimulating than seneka For p. 137 “Some authors state that the disease is entirely inflammatory not regarding the forming stage. If the forming stage is wanting we must rely solely on the antiphlogistic treatment” “This disease has a direct tender eye to death The physician must take it out of the hands of nature” “When croup supervenes upon catarrh as it frequently does of late year the mucous secretion and expectoration usually cease suddenly “When croup follows diseases that prostrate the system powerfully as angina maligna, there is little chance for recovery. The sympathies of the system are broken down and Archimedes can find no fulcrum for his lever” “I used tart. ant. at the commencement of my practice and succeeded with it as well as I could wish I therefore contained it, but only in the early stages & to produce a powerful orgasm. If it acts upon the stomach only it aggravates the disease Other practitioners rely upon different articles & probably with equal success bearing in mind however that a powerful impression must be made Decoct. sang. to prostration & vomiting seneca or lobelia inflam with the same view” “Sulph. copper & zinc & acetate copper useful to assist in the latter stages or when other emetics are worn our. So also hives syrup which is much used at the south.” “For six or 8 years past croup has been occasionally different from the pure inflammatory. It affects the lungs and duodenum& calomel and cathartics are the remedies to overcome this form. The cough is more frequent and loose the paroxysms less distinct there is pain in the epigastrium vomiting & a membrane is formed in the duodenum which passes off. I have called it angina duodenitis. The same year ulcerated sore throat came on with it the slough leathery & like a burn it seems to be intermediate between A. tonsillaris & A. maligna The application of lunar caustic by a pencil or brush would prevent croup Blisters to the throat & chin were useful yet a blister would produce the same action as existed in the throat, forming an ulcer very difficult to heal Slough ¼ in. deep 3 mo. in healing. In one case the blister cured the croup and the ulcer killed the patient It is desirable to translate action to parts less essential to life. Cal. & carth. would translate it to the duodenum Emetics & powerful treatment do hurt here. The vapour bark is good. “Croup sometimes recurs several nights in succession A. Laryngea is more apt to do so” “When crop assumes a chronic form emetics irritate inhalation of vapour blisters opium diaphoretics & expectorants” “In chronic croup the inflammation in erythematic and not membranific. The vapour bark often does wonders Tartrate of sanguinaria in ¼ gr. doses Tinct. hyoscyamus gtts x N.B. Dr Woodwd treat of subacute ([S?bertonic]) & typhoid croup the latter contraindicating tart. em. & requiring sanguin. turp. mer. calom. etc. & sometimes capsicum, ammonia & even perhaps wine & alcohol. “One of the most extraordinary examples on record however of the effect of disease in developing of perceiving a certain class of relations is that of [Zerab] Colburn His history is well known When quite a child in his sixth year, without any previous instruction, he could by mere intuition perceive the relations of numbers with so much readiness and precision, as to solve almost without reflection questions in arithmetic which would require a long calculation to enable others to answer. How he obtained this result he could not tell. The answer seemed to present itself to his mind with the same readiness and conviction of its truth, that the proposition tow and two make four does to us. These facts I saw are well known, but it is not so well known, that this power was the effect of disease. That such was the case I have very little doubt This was the opinion of a very distinguished physician who saw him at the time, and who ascertained that he was then affected with a peculiar nervous disease the same (chorea) which Jane had a few years since. In conversing with Mr Colburn about a year ago I asked him if he retained the power of calculation which he possessed in his childhood. He said no, and attributed the loss to the want of its exercise. But why should exercise sustain a faculty in existence which was spontaneously developed?” “Account of Jane C. Rider the Springfield somnambulist; by S W Belden MD. Springfield 1834” p. 108 “The discovery of Zerah’s power of calculation was purely accidental Zerah not having yet completed his sixth year was overheard by his father, as he repeated to himself in his play, parts of the multiplication table. The father surprised proceeded to examine him & [found] etc. 1 Diseases of children [B illegible 31] Proposed plan name – history symptoms & causes [Regar] plan of treatment minutely described Other modes of treatment Miscellaneous remedies N.B. Collect all his remarks on art of practising medicine Contents page Introduction Tumour of the head from difficult parturition 5 Cutting the frenum linguae 5 Congenital hydrocele 5 Management of children – as to Particular appetites – Preventive medicine 5 General nature of the diseases of children 6 General operation of remedies in children Diseases within the month Retention of the meconium 8 Jaundice 11 Acidity, Flatulence, Hiccough etc. 12 mothers milk & cows milk 12 Costiveness & its consequences 12:a Vomiting 12:d Diarrhoea 12:f Prolapsus ani 12:l. Aphthae 13 Eruptions in general 19 Strophilus interlinctus or Red gum 19 Strophilus candidus 21 Crusta Sactea 22 Eruptions of Dentition 24 Eruption resembling the itch 24 Venereal Eruptions 25 Infantile Erysipelas (Rose rash) 27 Sore ears (Intertrigo) 30 Tinea capitis [???phlicus]- [illegible] [illegible] on [illegible] [1821-2] 32 Dentition 34 Cholera Infantum 40 Infantile Remittent 55 Mesenteric Fever 61 Tympanitis 66 Worms 69 Volvulus 86 Nervous Rheumatism Infantile [remedy] 89:a. Convulsions 90 Epilepsy 96 Catalepsy 99 Chorea 100 Ulcerated mouth 103:a. Gangrene of the mouth 104 Parotitis or mumps 112 Tonsillitis or Quinsy 115 Rosalia or Scarlet fever 120 Croup or Bronchitis 132 Laryngitis 139 Epidemic catarrh resembling croup 141 Whooping cough or Pertussis 144 Rickets 158 Scrofula 162 Mesenteric fever Hydrocephalus 164 Chilblains 176 Painful aff. from cold without discoloration 177 Burns 177 The cause either is to be found in [???uctural] [illegible] for the [illegible] This will [illegible] men to trust their lives to unknown men, or to fictitious names in the newspapers, where they would not trust property even to a small amount # Formerly prescription of an experienced physician very often set aside for that of the nurse or a negro woman 1 Diseases of children 1 In this part of our course I direct your attention to the history of man in relation to his habits, diseases, & their remedies in his infant state That this subject has occupied the attention of the learned less than any other branch of the medical profession, is universally acknowledged 2 – It is unnecessary for me to enforce the importance of the subject, by any remarks which might be made concerning the evil to society from a neglect of a part of the practice in which the community is so deeply interested 3 – I need but advert to the evils which must result from the practice of committing the management of the diseases of infants to a class in society which is the lowest in point of intelligence 6* [the opinion of the nurse is sometimes taken in opposition to that of the physician – On this subject the world seems to desert its principles of reasoning on other subjects. If a point of law is to be decided men will not trust to a petty of the court, in preference to that of an experienced If a text of scripture is to be explained, men apply to a learned divine in preference to the mere servant of the church & on the subject of wearing apparel it prefers the opinion of the master to that of the apprentice.] 4 – That this subject has occupied the attention of the learned less than any other branch of our profession is universally acknowledged. (The French & Germans however, have neglected it less than the English; and the American physicians have been in the habit of paying more attention to diseases of children than the Europeans) 8 Great attention has been paid to diseases of children within the last 30 or 40 years It has been most neglected in Europe, but less by the French & Germans than by the English 17 European practice differs from ours – but less so at present than formerly because the constitution of our countrymen are coming to resemble those of Europeans 12 It is also the case that European diseases differ from ours on account Disease, here is [illegible] more violent owing probably to the greater of climate etc. Angina [Trachealis] is much milder with them & requires much milder treatment # vicissitudes of the weather 2 5 - The causes which have excluded physicians from the treatment of [infantile] diseases infants, having ceased to exist the subject is now receiving the attention which its importance demands 6 – These causes may be enumerated in few words – viz. the exclusion of the faculty from the practice of midwifery – from the difficulty of obtaining correct ideas upon the subject from its obscurity – the prejudices of the public on this subject – attributing as they do intuitive skill to nurses and matrons * vid. page [illegible] & perhaps also the indifference of the profession 7 – At the present period, however, the enlightened physician watches the mother during the whole period of gestation, receives the child upon its first introduction to the light, & prescribes for its diseases from infancy to old age 9 – As knowledge however must on this subject, as on every other, be progressive, it follows that this part of the profession having but recently received the attention of physicians, has not attained the perfection of the other branches 10 – American physicians need American treatises on this as on other medical subjectds 13 – European practice, as exhibited in their works, is too slow and mild to meet and overcome the morbid excitement of acute diseases in our climate. [Chronic diseases may be treated They practice no deceit 3 with mild remedies, but acute diseases are made worse by remedies if those remedies are not sufficient to overcome the disease The action of the remedy falls in with the diseased action and aggravates all the symptoms if it is not powerful enough to overcome the diseased action IN such cases disease is to be taken out of the hands of nature. The powerful [enemy] is not to be irritated unless there is a prospect of overcoming him] 14 – The difficulty of acquiring a knowledge of the seat of the diseases of children, on account of their being unable to communicate their sensations by language, has been made an excuse by some physicians for neglecting the subject of infantile diseases We may remark however that the difficulty of attaining a correct knowledge of a subject, cannot be given as a reason why it should not be committed to men of intellect & science 15 – Though children cannot communicate their sensations by language, yet the other symptoms by which we determine the seat of their diseases are more uniform in their appearance & more certain in their indications than those of adults 16 Children are under no restraint from feeling fear, [delicacy] or from false modesty In the infant, the mind does not react upon the stomach & destroy its function When Dr Harris published his essay on the acute diseases of children Sydenham said to him “you are the first man I ever envied and it is my firm belief that your little book will be more useful to mankind than # Adult patients also will often deny the existence of dangerous symptoms; for fear they shall be considered as very sick The subject has not yet been thoroughly investigated. No regular course on it has been [illegible] until quite recently in [illegible] of the European schools. I recollect the embarrassment under which I laboured under at the commencement of my practice Cases frequently occurred which were not described in any of the books [&] I was obliged to acquire all my knowledge on the subject from older physicians or from experience. My students have often expressed to me the satisfaction they experience from an examination of my notes and they have often quieted the anxieties of parents by reading extracts from them # In my embarrassment upon being first called to a sick child though familiar with the treatment of adults & having attended the first schools in the country I found my information & in books as to [illegible] nature or treatment and was obliged to have recourse to the older physicians 29 [Dewers] is popular addressed to mothers, very prolix & not intended for a text book but perhaps able [work] & is the 30 [illegible] # Parents think a young physician will do well enough for a young children and are much more apt to call one in for such patients 4 mind does not react upon the stomach & destroy its function We are at no loss how much to attribute to disease & how much to [illegible] # 17 – Still with all these advantages & notwithstanding the importance of the subject it has been neglected & has received less attention than any other branch 18 – When Dr Harris published his essay on the acute diseases of children Sydenham said to him, you are the first man I ever envied, and it is my firm belief that your little book will be more useful to mankind all I have written” This opinion was not founded upon the merits of the book but upon the fact that the attention of physicians would be drawn to this part of their profession, not the least useful though the most neglected 25 Authors on this subject & their merits 26 Underwood Still the department has received less attention than any other branches of our profession 27 Dr Rush in his works, has many remarks 28 Periodicals contain more or less upon the subject 21 – No courses in any of the schools 19 – Some physicians of the first respectability have acknowledged their ignorance & given up to nurses 20 – I recollect the embarrassment I suffered upon this subject # It is a common complaint 22 Since I have lectured upon this subject, our students at parting have expressed their satisfaction. 23 Young physicians are first called to children because the older ones neglect them # hence its importance to them 24 Parents however seem, as a matter of fact, to prefer a young physician, for a young patient! # 34 – I shall first remark upon a few surgical cases which occur to the young physician soon after the birth of the child [illegible] cutting the frenum. I have never seen a case in which this operation was necessary. It is very common for nurses to insist that children are tongue tied. Dr [Eneas Munser] was called in such circumstances he remonstrated the nurse was instant until finally he drew the back of a knife across the frenum & the child he told [illegible] [illegible] hurting and this with this [result] was relieved to the great satisfaction of the nurse. If there is a false frenum it may be divided.” this [illegible] [frenum] is never so short as to confine the tongue & cutting it is a dangerous operation # They will tell you that this particular appetite is indicated by the natural crying of the child The mother will set herself to recollect some former longing of her own [illegible] 6 Hydrocele Young physicians are often called on to prescribe for congenital hydrocele in young children The complaint is apt to excite alarm but neither troublesome nor dangerous. It is readily distinguished from [illegible] by its transparency, insensibility, & not yielding to pressure. In the course of my practice I have had to operate in but one case in children. Dr [Dewers] recommends pouring considerable quantities of cold water on the part. I myself have frequently cured it by washing the part with cold water in the morning and applying camphorated spts in the course of the day. You [illegible] direct the application of spirt & water, camphorated spirits, [muria??] of ammonia, [opium], spirits of nitre, in short every discutient Or you may direct astringent lotion, as a strong decoction of maple bark, spriaea Fomentosa Geranum, Rhei etc. Case in which I had to operate year old probably neglected 2 or 3 inches long about as large as a small egg. Operate without a cannula - with a lancet & catheter & injecting syringe – water 1/6 or 1/8 port wine – children more irritable - vomiting 5 Tumor on the head 35 Children are sometimes born with a tumour on the head occasioned by difficult labour This may be distinguished from a tumor caused by a deficiency in the bones of the cranium, by a uniform hardness. “We may apply mur. amm. or spt & water” 36 – Cutting the Frenum 37. Hydrocele 31 Management Appetites 32 A prejudice prevails in some classes of society with respect to a point in the management of children Some children are thought to be born with a strong appetite for some particular kind of food, which was possessed by the mother previous to the birth of the child & inherited from her. It is thought that the child will [pine] & ultimately die, if this [illegible] appetite be not gratified # It is probable that a belief in this doctrine has caused many children to be killed by the administration of improper food A fact of this kind occurred in Humphreysville, which nearly proved fatal to the child. Vide next page Preventive medicine 33 As a general rule medicine is not to be given to children in health for fear they should be sick. Some are nursed to death, while some die for want of nursing. Some are fed to death while others are starved Some are physicked to death while others die for want of medication injection immediately with [draw] healed [illegible] with swelling The child cried much # - a council of females was called who set themselves to make out what the child needed Finally the mince pie was concluded to be the article the child sucked down the inside & the report was that this effected a cure & saved the life of the infant. Prof. I inquired of the attending physician who informed him that the child was indeed alive and well at present but that it was made very 8ll by the mince pie & came near losing its life. The crying of the child in this case was probably nothing more than a trifling increase of the ordinary crying of very young infants, which is a natural and wholesome exercise # The al. can is large in proportion to the [illegible] of the whole system # The above is a good example of the various prejudices which have prevailed among [nurses] respecting the management of children. Owing to the influence of enlightened physicians these are no disappearing. (examples to be given) 6 38 – Diseases requiring medical treatment General considerations 39 – In investigating the causes and seat of the diseases in infants the mucous membranes claim particular attention 40 The action of this membrane is greater in the infant than in the adult constitution Its secretions are often morbidly increased & are sometimes diminished. It is subject to spasmodic action and to inflammation [illegible] with [illegible] or decomposed with effusion of coagulable lymph. “It is subject to turpidity & to spasmodic action which by sympathy extend to the whole system 41 The liver is much larger in proportion to the body the infants than in adults “& its secretions are much of [illegible] as to quality & quantity than in adults” 42 The secretions are much concerned in their diseases. They are changed as to quantity and quality # Prescott child no ducts lived 3 or 4 months and was excessively emaciated – there was no bile in the stools There was no [previous] duct for the gall bladder into the disorder # There is greater susceptibility to action & tendency to conversion # Just as emetics are given to a stomach [complaint] from excessive quantity of food 7 42 The nervous system of infants is more easily excited, and more affected by the various causes of irritation such as dentition worms acrid substances in the first primae via passages etc. 43 – The blood vessels are more rarely the seat o f disease in infants than in adults – particularly, primarily so much as irritative [acid] if they were affected the action is not [illegible] 44 – Consequently their fevers are fevers of irritation, rarely enteric or those of inflammation 45 Operation of medicines Children bear evacuation better than adults witness the long continued diarrhoea without much debility following, or the salivation for mouths during dentition without a waste of vital energy In operating upon the abdominal viscera it should be [illegible] it is not for the purpose of mere evacuation, it is to produce an excitement for the purpose of overcoming a morbid excitement also to produce healthy excitement a case of torpor # The milder purgatives should be used, the drastic being irritative. Emetics Bleeding Do not bear narcotics vide p. 11 2 – In general the evacuation of the meconium should be effected by the [colostrium] or first milk of the mother which has a laxative property # The child should be put to the breast within 2 or 3 hours from birth # unless [illegible] Instead of suffering the nurse to feed the child for the first 2 or 3 days the breast should soon be presented for if the child feeds it is in danger of losing the instinct to suck If the [colostrium] does not bring away the meconium we may begin with soda as mentioned below or with cold sweetened water Some give a little cold water at first vide [infra] 5 – In strong children cold bathing may be employed with advantage, but the bath should be made tepid for weak ones & gradually used colder as the child can bear it # “If from the exhaustion of parturition the mother be unable to suckle let the nurse commence feeding at the end of 3 hours” vide infra Give a grain of carborate of soda in a teaspoonful of water until iii qts [have] given # The meconium is frequently evacuated during parturition. After birth also the al. canal is set in notion by the crying and mother of the child and the stimulus of the air upon it vide p. 10 skin. # Colostrium is of a yellowish colour probably contains bile & is cathartic # It was formerly supposed that the child should not suck at first. The consequence often was that the child lost the interest to suck 8 Retention of Meconium 1 – The first diseases of infants which claim the attention of the physician are those which arise from retention of the meconium. The meconium is a matter always existing in the bowels at birth & having a dark green colour when evacuated. It resembles tea but is more mucilaginous # It will ordinarily be sufficient to give a little molasses and water to the child until it receives the [illegible] or first milk from the mother which has a laxative quality 6 – If it is suffered to remain a train of diseases may follow. In the diseases which occur within the first moth after birth the retention of the meconium is always to be suspected as the cause 7 – The diseases caused by retention of the meconium are Severe paroxysms of pain in the bowels indicated by crying & writhing – Tumefaction of the bowels. Convulsions. Epileptic fits. Trismus nascertium or Locked Jaw This last disease is very common in some of the West Indian islands, but I have never seen it in this place 8 – Whatever disease may arise from retention of the meconium the principal indication will be to remove the irritation by evacuating the bowels. This is effected by cathartics. A teaspoonful of castor oil is generally sufficient. If [illegible] necessary 1st indic to remove meconium 2nd obviate effects # IT will be sufficient to pour on boiling water instead of boiling the materials in the water The strength however is of little consequence Sometimes the most powerful remedies are to be used beginning with mild. These used full doses of calomel, scammony 2 to 4 yrs – [illegible] assisted by injection, & warm bath until the bowels were moved Wait how long for the operation of each? # By emollient injection, irritation is allayed, and if the lower part of the bowels is excited the rest will be Dose 2 to 6 pills each pill containing 1 gr. of (calomel) # Chalk & calomel is a substitute for blue pill – perhaps the chalk qualifies the cal & at least it corrects acidity Antimony should scarcely ever given to children within the mouth # A great part of the calomel has no effect [illegible] it does not come in contact with the coats covered with mucus In cases where there was great quantities of [mucus] I have given full doses of cal. 9 the dose may be repeated every 4th or 5 hours until half an ounce has been given 8 – If the oil is rejected from the stomach Senna & Manna may be given – zi of the former to zss of the latter boiled in gill of water # & administered freely until the bowels are moved once in ¼ or ½ hour “ Rx Sennae zi [illegible] ferv. 1 gill 1 or 2 teaspf every ½ hour” 9 – The operation of the cathartic should be assisted by emollient injection # 10 – Fomentations to the bowels will assist the operation of cathartics & if spasms exist, will always be needed for their relief 11 Cathartics of various kinds 12 The best cathartic which I have used for infants within the first month after birth is the blue pill (or [mellated] pill It rarely offends the stomach and never produces griping By it the action of the liver & the secretions from the mucous membrane of the intestines are excited more than by any other cathartic except perhaps calomel. In my practice I have never known an infant salivated by it. # 13 In severe cases where the blue pill is insufficient we must have recourse to calomel, which may be given in doses of from two to 10 grains. It is often necessary to give as large doses of calomel to children as to adults owing to the great quantity of mucus in the intestines by which they are defended from its action. # The meconium scammony or jalap as a laxative & had them operate mildly If the cots were [naked] [illegible] a dose would prove fatal for irritation # This is a mild cathartic and supposed to act chemically. # “Evaporate the [illegible] over the fire stirring it until thick then add chalk till it is of a consistence suitable for pilling Each pill may contain 1 or 2 gr. of Dose from 2 to 5 gr. Or it may be dissolved in herb Fish, gall has been recommended [illegible] gall Rattlesnake has been thought to have specific properties especially in fevers. This article is bitter, tonic [illegible], laxative, & [illegible] Continued from page 8 “The infant may be put to the breast in one or tow hours from birth This course will produce permanent contraction of the [uterus] & tend to stop [hemorrhage] & prevent milk fever” When an infant is first born it is well to wet its mouth with half a teaspoonful of coldwater and give it nothing else until it is applied to the breat 10 while retained will likewise prevent the operation of the remedy by involving it in its viscid substance 14 Chalk & calomel may be used in doses of 1 gr. cal. to 4 or 5 chalk repeated once in 2 or 3 hours 15 Other cathartics which may be used are or as recommended by Dewers 1 gr. carb. sod. to a teaspoonful of water repeated every “it operates” 15 minutes until 10 gr have been given. # Decoction of the flowers of the dandelion & the mullein Senna 2 dr. to with 4 dr. of aromatic herbs or seeds The bile of animals (ox gall) is a good cathartic Perhaps we may consider it as acting as a substitute for the childs own bile. It may be given in [catnap] tea milk etc. # 16 An injection of bitter or 16 aromatic herbs will allways assist the operation of whatever cathartic you use & in mild cases frequently will be sufficient of themselves – superceding the necessity of giving anything by the mouth Continued from p. 8 The stimulus of sound upon the child, crying, irritation of the air upon the skin, and especially muscular motion, excites the peristaltic motion of the child. The influence of muscular motion upon the peristaltic action of the bowels, is considerable, as is seen in horses while travelling, the costiveness of sedentary persons etc. “The warm bath at the temperature of 98 or 100 assists the operation of cathartics renders their action more mild equalises the action of the system and nervous irritation It is especially useful when convulsions are present and may be used at any period except in cases of extreme exhaustion” # It is the most powerful antispasmodic for children [have] acting upon the extremities of so many nerves Jaundice “Jaundice sometimes appears at birth indicated by the yellow colour of the countenance and arising from obstruction of the liver etc. Such cases are generally incurable. The first remedies are the mild deobstructant plant, small doses of calomel etc.” 11 When convulsions are present the warm bath should be used to assist the operation of whatever cathartic is used, to render the operation mor mild, to equalise excitement and to remove irritation. This remedy may be safely used at any period after birth # After the cause which excited the convulsions has been removed, if the morbid irritation of the nerves continues, the bath will again be serviceable 18 Antispasmodics may likewise be used such as valerian, aqua ammoniae, elix. asth. artificial musk infusions of catnip etc. We may use aqua amm. 3 or 4 drops or carb. amm 3 or 4 gr. or asafoetida a teaspoonful of the tinct. in milk & water, or camphor by enema Be [cautious] of giving narcotics to children Some are more susceptible than others. And some children are accustomed to [them] from birth. Case of a mother who had inured a child of 3 m. to bear 30 dr. of SS. I proposed to give paregoric, beginning with 8 or 10 drops, and found that the child had often taken with impunity 31 dr. of SS. to produce sleep 4 – “Child bed women are generally to be treated with mild diet for the first week after delivery, unless their strength has been much reduced by parturition, when they may take port wine in moderate doses” # “If light stools indicate a deficiency of bile the administration of oxgall will be found very serviceable vide [illegible] If acidity is produced, add limewater, If diarrhoea is produced, use arrow root instead of the water, or any other [fecula] Children are apt to receive too much food; hence cow’s milk should be diluted with water. Milk may sometimes coagulate in the stomach of children, in large quantities and occasion much uneasiness Meat should not be given under 6 mo. unless in particular cases which are exceptions to the general rule, where milk disagrees or perhaps in the case of some scrofulous children 12 Acidity Flatulence Hiccough 1 – Very young children are often troubled with acidity, flatulence & hiccough These affections may be removed by a free use of magnesia, lime water, or aqua ammoniae 2 – It will not always be sufficient safe? to administer these articles to the child alone. The mother or nurse must often take them likewise 3 – Sometimes the mothers milk disagrees with the child. This will be known by the constant disorder of the bowels of the child. by the evacuation and pain suffering after nursing both child and [illegible] mother may seem to suffer without a cause The stools may be slimy# The child may cry obstinately 5 – If the mother’s milk continues to disagree we may use cow’s milk diluted with one third or one half water & “sweetened” or with arrow root mixed first with a table spoonful of cold & then with one of hot water, in order to make a homogeneous mixture 6 – Children fed on cow’s milk are more apt to be costive. To prevent this give a little magnesia, decoct. of dandelion etc. Peach tree blossoms are much used, but are too violent in their operation The injection will start the machine again The injection may be made of Eupatorium, catnep, elderflowers mallows etc. etc. Apply first whatever can be first prepared counterirritants for instance. Spirit or mustard to the fat ammonia etc. ammonia to the mouth and nostrils etc. endeavouring to rouse the patient 4 – [A young physician should be careful to know what to do in sudden cases (much depends on a favorable impression at first) Neighbors and friends usually assemble around a child and the expect the physician will be able to prescribe at the moment. In such cases set some of the bystanders to preparing a warm or tepid bath – no matter if eventually if it should not be used. Set others to preparing some other thing and so on. Thus while the attendants are all employed he will be able to devise some course to pursue] I recollect an old physician in this situation who was pressed what to do & replied “stop let us think about it” 12:a. Costiveness & its consequences 1 – Physicians are frequently called upon to prescribe for infants who are in health except that they are costive Children fed from a spoon or bottle are mor to be thus affected than those who are nourished from the breast. If costiveness is produced by improper quantity or quality of the food as is sometimes the case, the diet must be changed 2 – Costiveness if not attended to in time produces flatulence, watchfulness, startings, hiccough, diarrhoea vomiting & convulsions 3 – A physician is frequently called to children I fits, who have been apparently well until the convulsions come on The safest and most efficacious prescription that can be made, is an injection & indeed is all the treatment that most cases will require. Let a warm bath be immediately prepared & the patient put in it if the enema does not relieve. While the convulsions continue the mouth is closed & we can operate on the system mainly by the rectum & the skin 5 Be careful to make your directions for administering an enema very definite, unless you know that the family are familiar with injections Case of a mason’s man hands & knees shooting somewhat off fright rolling over murder The enema may consist of simple warm water, or milk & water, or of tea of thoroughwort or catnep etc. a table spoonful of salt may be added finally castor or other oils may be thrown up in extreme cases the rectum has been filled with lard The water for the tepid 12:b. bath should be about blood warm. Be careful to bathe the child, & not merely to scatter or sprinkle water on it. The length of time during which the child may be kept in the bath may be from 5 to 20 min. While the patient is in the bath if it is sufficiently relieved to be capable of swallowing give a dose of calomel for a child of 6 months 6, 8 or even 10 gr. If improper food is the cause 20 gr. are not dangerous, for infants will bear full doses of cathartics though very small ones of narcotics In bad cases of convulsions the means to which we have it in our power to resort, are external irritants such as garlic draughts to the feet, injections of [nervines] the most powerful of which will be a teaspoonful of tinct. camphor thrown up in a gill of milk & water & the warm bath until we can administer articles by the mouth “If the child be feeble & exhausted upon coming out of the bath give cordials or tonics” Any quantity of food in the stomach & bowels which is not congenial, interrupts the process of digestion & the peristaltic motion functions whose importance is second on ly to that of respiration. When these functions are interrupted the muscles are brought into convulsive action to relieve the system Be particular in your enquiries about food for those who have the care of children are very careless and children will swallow whatever is put into the mouth. I recollect being called to see a very strange worm which a child had voided. The imagination of the attending physician & parent were excited. To me whose imagination was cooler the worm appeared to be a piece of bark I enquired if the child had had no slippery elm bark & found that it had been chewing some. Then the supposed worm was accounted for Rye flour is more apt to become acid than oatmeal # Cal. sometimes by its irritation produces convulsions I have known a family, all the children of which were thrown into convulsion by cal. & I was obliged to be very cautious & use blue pill injections etc. There are several milk remedies such as dandelion which is tonic laxative, & deobstrument acting on the liver, mullein fl. elder [blo??] tea “The pollens of most plants has a laxative quality” I have seen no danger from the prussic acid of the [illegible] flower & it is much used [illegible] from [illegible] also among the French they hold a place the French Pharm. Wild liquorice [gal??] [Circa???] resemble the dandelion Moderate friction excites the bowels Sometimes alkalie or chalk, though generally they are rather constipating, prove laxative probably on account of the acid combining 12:c. II II Where is a tendency to costiveness, the use of oatmeal gruel or porridge will be beneficial or a porridge made of wheat flour with the bran, strained through a cloth & mixed with the milk with which the child is fed also rye meal gruel or rye bran gruel If the health is not affected by the constipation be cautious about giving much medicine. It is always better to cure this affection by food than by medicine. # Castor oil from a teaspoonful to a table spoonful is the best cathartic magnesia given with the milk is a good remedy but not always sufficient. Elixir salutis is one of the most common family medicines. This article with castile soap dissolved in it has been found very serviceable. The gall of animals may be recommended. The blue pill operates gently as a cathartic & is useful in changing the habitual disposition to costiveness. I have prescribed with advantage decoction of the flowers of the dandelion, or mullein. The flowers of the peach tree are much used for the same purpose but “are rather too powerful for ordinary cases” “They are powerful even for adults” & sometimes gripe unless combined with aromatics Calomel may be used with safety # “In severe cases mustard and ginger may be applied to the abdomen” Mechanical manes in the form of suppositories are much used by nurses such as a piece of molasses candy or a roll of paper moistened with oil. They are beneficial. # If the child has been weaned pay particular attention to its food. Nurses are very careless. # “No serious evil will arise unless young & anxious mothers should give medicines and thus make the child sick” “If vomiting arises from dentition we must remove the irritation Give laxatives, as magnesia, & narcotic Children should be early accustomed to the reception of enemata to prevent subsequent prejudices upon the subject. I recollect the case of a child about 12 who was suffering from an obstinate constipation caused by an affection of the lower spinal nerves which produced a partial paralysis of the rectum and bladder so that a catheter had to be introduced & injections were [illegible] demanded. But all the efforts of the nurses (women) were unable to administer an enema Calomel had been given until the mouth was affected, yet without producing an evacuation. Finally the patient went into an insensible state, and injections were given & produced free evacuation. I have heard adults say they would die before submitting to receive an enema. 12:d. Vomiting Spontaneous vomiting in infants arises from over distention of the stomach. The discharge is made without nausea & almost without effort, & consists of pure milk or milk coagulated. The mother should simply be cautioned not to allow the child to nurse so long at a time. # Children and old people vomit with more facility than the middle aged If vomiting arises from the sympathy of the stomach with some other part of the system which is in a morbid state, the primary disease must be first cured & used for the irr. of stom. For the vomiting itself in palliative we may prescribe lime water & milk. a teaspoonful of each; soda water, or any liquid affording an abundance of carbonic acid. Vomiting from irritability of the stomach or free [illegible] requires particular attention. The attendant symptoms will be paleness of the countenance, quick & feeble pulse, & cold extremities. Irritants must be applied over the region of the stomach. They may consist of ginger, mustard, horseradish leaves, mint etc. aqu. amm. [illegible] essent oil dissolved in alcohol” The alkalies such as pearl ash, also soda water “lime water” may be given internally. Excite a discharge from the bowels by injection or a calomel cathartic to remedy the irritated action of the stomach “[illegible] counterirritation” The warm bath will be very serviceable, soothing the nerves of the skin & by sympathy producing the same effect upon those of the stomach nervines also may be given We may try putting a little brandy into the mouth or a small quantity of capsicum tea. Hot cloths & fomentations may also be applied externally. A large bulk of warm water water may be thrown up the rectum in obstinate cases, use stimulating injections.. One of the most convenient modes of administering a large injection is by a pipe fastened to a large ox bladder Press the fingers against the end of the pipe which the bladder is fastened so as to make a valve and prevent the escape of the fluid contained in the bladder, until after the pipe has been completely introduced into the rectum # I used to carry this recipe about me when I practiced in the country Frequently irr. of stom. is overcome by irr. o f the rectum by an enema of salt & water or by a large injection to produce a peristaltic motion downwards 12:e. Ren “Remove the cause, which is frequently indigestion. If it proceeds from the teeth, lance the gums The following is an excellent recipe # in these cases Rx Cret. ppt zii sem. card. zi bi carb. potas. zfs grind aqua bullientis 0 fs Give a tablespoonful every half hour I am inclined to the opinion that the alkalis, such as pearlast act by creating an excitability Emetics are particularly safe for children much more so than for adults. Ipecac is generally the best unless the disease in which the emetic is indicated is very threatening, when antimony should be used Squills are indicated in emetic doses in complaints of the chest “with [illegible] [illegible] but should not be administered when there is much inflammatory action in the system. “Warwick’s powder a preparation of antimony, was once popular and often administered without the advice of a physician. I have known it endanger life Nurses should never prescribe antimony” Some situations are more liable – low situations [seashore] Children shut up in low dark apartments suffer from want of amusement. If a diarrhoea from teething is suddenly stopped the brain is apt to be affected. This affection of the brain is peculiarly liable to occur in children. There is no outlet to the brain 12:f. Diarrhoea This complaint sometimes affects children for months & even years Some families are more subject to it than others & I have known those in which all the children would be affected with diarrhoea from a period soon after birth until they were three or foru years old. The children who have this predisposition to the disease are born with diseased liver and bowels & have indeed all the chylopoietic viscera in a disordered condition. Hence among the causes of diarrhoea we may rank a bad constitution. Other causes are want of cleanliness, bad food “want of sufficient clothing” bad air damp rooms, confinement & want of exercise. Exposure to cold & moisture A bad air probably causes diarrhoea mainly by its depressing influence. The effect of confinement and want of exercise is very great. Young animals suffer in the same way Even vegetables seem to need motion for I think I have observed a great deficiency of fruit & a sickly appearance of fruit trees after a season uncommonly free from wind. Confinement is injurious in another manner Children need mental stimulus from a variety of external objects. I have known surprising cures effected apparently by the operation of this very principle. Teething is a frequent cause & whenever it is we must palliate & check, but may not stop the diarrhoea From the sudden stoppage of a diarrhoea during dentition you may expect an affection of the brain to follow. The discharge from the bowels in this case is similar to that of tears from an irritated This will be convenient in many cases as in travelling Other mints may be used spearmint is most agreeable I have given this in the latter stages of the diarrhoea of adults with advantage Almost any cath. will often check a diarrh. Cal or blue pill is generally best Judgment is to be exercised whether to prescribe an emetic or a cathartic & as to the choice of a catheter Ipecac however is almost always safe children bear emetics well Put the parents & the nurse upon investigating as to [diet] Persons are apt to very careless about giving things to children And they may have wrong notions as to particular articles Prohibit solid oily food, crude vegetables and esculent roots. Potatoes are very bad in diarrhoea so are the analogous roots. They contain indeed much fecula, but also much 12:g. eye, or of mucus from the lungs The expressed juice of mentha vulgaris, boiled skimmed and mixed with white sugar is an agreeable, & useful article for the cure of a diarrhoea, which has continued but a short time & is not severe. In the early stages of a diarrhoea, which is sufficiently severe to demand the attention of a physician it will generally be best to commence the treatment with a cathartic; though if fever accompanies it an emetic of ipecacuanha should be the first article administered. Judgement must be exercised in the choice of a cathartic. Calomel will be best if the child be not particularly feeble or of a very delicate constitution & for a feeble child the blue poll. I myself was for formerly many years unable to take any other cathartic than the blue pill without being griped. Generally it will be best to combine chalk with the calomel, as the latter is indicated for its deobstruent, rather than for its purgative effect. The dose may be about 2 gr. cal. with 5 or 6 of chalk If improper diet is the cause the food must be changed; & it will generally be necessary to be particular in our enquiries with regard to the diet for the parents may consider many things a safe which would be strictly forbidden by the physician. Especially will it be necessary to attend to the diet if the child feeds instead of sucking. Every thing hard of digestion, such as salted & oil food should be prohibited The diet should be arrow root and in case of diarrhoea this article will be improved if prepared with a little laudanum or wine sago taipica, which is probably a hydrate of besides They are apt to become acids & acrid in the bowels. In the Polyn. islands The inhabitants living upon taro are very liable to diarrh. West of the Rocky Mts Lewis & Clark found the inhab. subject to diarrhoea for living on a root [illegible] [illegible] men suffered in the same way after they arrived among them In the evacuations & the evacuations of children shd always be exam [may] [illegible] that potatoes remain undigested Cullen & Rush thought different of potatoes The evac. of chil. should always be [illegible] Pies cakes articles containing much sugar hot bread should be prohibited Bread shd be toasted The juice of meat will often be beneficial No gravy (i.e. artificial or carbonized fat with flour etc.) Potatoe starch, pure, is perhaps not inferior to the tapioca etc. Boiled flour becomes s hard as stone almost hydrate It is an old practice It is an excellent preparation make a porrige of it grated Tapioca I suppose is made by sprinkling casserva root, powdered, with water & baking it making a preparation what appears like gum arabic. I have not been able to learn how it is made, but have made it this way a similar substance of arrow root Arrow root & the tapioca are cooked by first dissolving them with a small quantity of cold water & then adding hot water. In this way [illegible] are avoided 12:h. flour or roasted or baked flour made into a porridge with equal parts of milk and lime water. The bread should be toasted and butter should be used very sparingly gravy not at all. Casserva sago etc. An article similar to tapioca, if not the same may be made in the following manner. Tie up a quantity of wheat flour tightly in a clean cloth & boil it for 5 or 6 hours The result will be a hard substance which is to be grated & “[illegible] milk & water or with lime water” made into a porridge this will be palatable & good Rice in gruel, or thoroughly cooked by boiling The worst cases of diarrhoea are attended with feeble pulse, cold extremities, dry skin, & generally a rise of fever once or twice in the 24 hours. Soften the skin by the tepid bath which is [illegible] etc. and keep up an action on it by flannel unless there is fever & in such cases use also absorbents freely with tonics & aromatics. The chalk julep or white decoction will be as good a preparation as any. Rx Chalk [illegible] zfs to zi pul. cinnam. to zii zii, bum arab zi carb. potas. zi water lb I. boil ½ hour Sometimes [illegible] a similar recipe shd be used” The Europeans add [illegible] use [illegible]” a little laudanum may be added. Of this feed freely, giving say a table spoonful from ½ tab sp. to I once in an hour sometimes. As a tonic the vitriolic or tonic solution of Moseley is inferior to none in such cases Rx zinci sulph ziii alum zi water lbi Give from four to twenty drops. Tonics must sometimes be combined with absorbents Opium is always safe in cases where the bowels have been thoroughly evacuated. It is generally better to combine it with ipecac, which will determine its action to the skin and act as a gentle tonic & laxative The tepid bath is [illegible] as it may be called) relieves the irritation of the bowels through the skin Chalk does not act mechanically or chemically it has a specific action upon the stomach as much as bark Make white decoction in various ways if cinnamon offends use some other spice Sometimes add astringents or [illegible] Tonic sol. sulph [illegible] ziii al. zi Mosely sometimes used al. zii In 3 or 4 gtt it is anti emetic In larger doses it may be emetic & cathartic This is a state of the system similar to the collapse of cholera Asiatica It is a collapse taking place during diarrhoea. I have found advantage from stimulating or acrid injections as salt & water, mustard In chronic diarrhoea opium is often invaluable. Some families are obliged to give it 2 or 3 times a day for along time to their children until they are so old as not to be liable to continual diarrhoea The stools may be green clayey from deficiency of bile sour curdled [illegible] or very fetid, so much so as to be very offensive turning the stomach of the attendants. 12:i. In cases of chronic diarrhoea where there is attending it much sensibility and irritability of the bowels opium combined with diaphoretics cathartics or tonics is an invaluable remedy Sometimes violent symptoms supervene vomiting supervenes & the diarrhoea stops the patients hands & feet grow cold his pulse grows small, & if the most active measures are not take used the patient dies in 24 hours. When this change of symptoms take place we must resort to the most powerful means of exciting counterirritation such as application to the epigastrium of mustard, horse radish leaves ol. monardae punctulae, ol. turpent. etc. Such articles as pimento will be grateful and stimulating given internally We may give calomel, opium & the carbon. acid, and use stimulating injections. “Effervescing mixture with SS. [illegible] appt” Particular attention should be paid to the kind of They may be sour & curdled, or mucousy, [illegible] clay colored, water stools for much may be learned from their inspection. Acid is often formed in the whole alimentary canal, producing sour and curdled stools which will indicate lime water or other absorbents, with aromatics. The acid may arise from fermentation or more probably from secretion Such cases I have often cured by the expressed juice of the spear mint prepared as above mentioned & given freely. When the stools are green white, or clayey, give opium to allay irritation. Ipecac to equalise excitement, & the blue pill as a deobstruent, the latter in small doses so as to move the bowels, but once or twice in the 24 hours. Alkalis are useful as # Noel’s plaister was made of white lead red lead castile soap and olive oil, boiled till the red lead was so far decomposed by the oil that the mixture was of a cream colour It is a smooth plaister and is less stimulating than [illegible] Use soft charcoal by burning cork, which is the popular kind or cedar Dose teaspoonful to a tablespoonful in a convenient liquid Lime water & other alkalies may always be given They may be mixed with the food without [injurious] the taste When the disease has continued long & patient is [illegible] phlegmatic temperament we may bandage the bowels, to give mechanical support [Opium] also will be useful applied externally in this way Adults from the Wt. I. with chronic diarrhoea will look like a mummy Bog water is a very soft water & contains carb. hyd. Astringents [illegible] tinct. vitriol decoct. of oak bark with milk & sugar & spice Bandaging & plaisters Take any adhesive plaster and mix about ½ opium Or soap and opium Acetate of lead is not a new remedy 1 2 or 3 gr a day 1 gr at a time continued as long as the relaxed state of the bowels continues as long as they last lead [cholic] cannot take place for 12:j. are also enemata formed by dissolving castile soap in mallows or catnip tea. If there is much griping with tumefaction of the bowels injections of camomile tea give great relief. In diarrhoea of this kind the following is also a good stimulating & correcting laxative Rx castile soap zi elix. sal. zi dissolve & give it 3 or 4 times a day of teaspoonful or ½ teaspoonful doses. If the stools are fetid give charcoal internally. It will correct the fetor & it sometimes cures the disease. For sour stools vie last paragraph of this lecture During the long continuance of chronic diarrhoea it will of ten be advisable to apply mechanical support to the abdomen. We may apply a plaister of white diachylon [illegible] plaister alone or with opium or of lead and soap & a bandage. In chronic diarrhoea the skin becomes brown, of a dark & dirty appearance, & very dry and husky If the tepid bath does not relieve this symptom, we may apply water from peat swamps, which contains carburetted hydrogen. Vide Duncan’s commentaries In the last stages of diarrhoea we must resort to tonic solution to astringents, absorbents & aromatics we may also use opium with cathartics, emetics & absorbents & If we met with a great craving for salt food it should be gratified. The gratification of such an appetite will prove a stimulus, especially to the mind & consequently the more powerful. We meet with similar cases among adults also. Case of a man who could retain no medicines upon his stomach & finally recovered upon bread & cheese, given at his request In the latter stages also of chronic diarrhoea, acetate of lead the [illegible] [become] very lax and there is generally a prolapsus ani patient being [semiphlegmatic] I saw this article much used in this way when a young man and though expecting bad colic no injury resulted. Prof. Smith was very fond of chocolate [illegible] It sometimes acts like a charm Spiraea may be given in decoction or extract. [illegible][illegible] is not so good being unpleasant having a fishy taste & offending the stomach Ger. mac. & [illegible] [arom.] are pure astringents & unobjectionable on this score. I have prescribed sometimes one, or another, according to convenience of locality where I happened to be The root of typh. latif. is used as food by the aborigines European physicians give [althea] [illegible] which is the true marshmallows Usually when diarrhoea has continued long the kidneys become affected. Mucilage will then prove diuretic probably by their [illegible] affect. The terebinthinates will then be useful. The most common practice in this neighborhood is a decoction of white pine bark especially with a little milk it is called healing to the bowels. There is also nutriment in it for the aborigines, sometimes live on it When mucilages to wear out we may resort to terebinth. The species of [polygnomic] knot grass are 12:k. may be given internally. There will be no danger of the production of colic, by this remedy, for the bowels are too much relaxed. The astringents just mentioned may be various We have at least fifty indigenous vegetables, which may be used given in decoction of milk or water such as the bark of the currant, the raspberry, the various species of oak, of viburnum chocolate of acorns etc. white pine bark in milk etc. the roots of the [illegible] of the [geranium] etc. The viburnum Especially deserving of recommendation are the spiraea tomentosa & cornus circinata. The latter of which equalises excitement Of mucilages we may have occasion to use a variety for irritation for any one article may become worn out & another be more grateful We have typha latifolia, twigs of sassafras, hibiscus, malva bran, flax seed, slippery elm, gum arabic etc. all the mallows, all the [illegible] marshmallows hibiscus palustris called rose of [illegible] in the gardens root is [illegible] [illegible] & sub astringent Sour stools Be particular in forbidding the use of animal food. If there be want of bile, give ox gall, lactescent plants dandelion etc. with mild mercurials; e.g. calomel 2 gr. with 6 gr. chalk. Aromatics also may be combined. Astringents elg. [illegible] speraea cornus & geranium do well. Also the following Rx calc. magn. zfs rhei palm. gr. 8 acaciae zi ol. anisi gtt vi aquae purae zi Give a teaspoonful at a dose. “once in 2 hours” In bowel complaints with griping attended with green or sour stools Rx magn. ust zfs pulv. rhei grs viii pulv. gum ar. zi ess. menth pip. gtts vi water zi dose, teaspoonful Spiraea & cornus used – they are mucilaginous sub astringent & diuretic Articles of a stimulating kind are often needed in the latter stages especially erigeron canadande (colt tail) [illegible] The bitter [illegible] which grows in similar situations (ambrosia [elatio??] is also used as a bitter apparently nervine in diarrhoea Roman wormwood) [Cupron] is acrid, sub astringent & diuretic much used in the middle states improper when there is entonic action case of cholerine cured last summer by this garden young man called etc. chewing the plant etc. The other species of erigeron have similar properties espec. E. phil. Various recipes are given for diarrhoea in children Ex mag. zfs rhei gr. 8 [illegible] zi ess. pep. gtts 6 gum ar. zi The popular remedies are generally absorbent [illegible] mucilaginous astringent etc. Much benefit may often be derived from copious mucilaginous injections mutton broth is the most popular probably other broth (fat meat) would answer still mutton suet is less apt to become rancid. It is thought to be useful also as nourishment I have not though much of this may of nourishing Laudanum may be added Also laudanum & starch injections may be advisable to check the excess of the discharge It will generally be best to begin with about 10 drops of SS. though a teaspoonful may be required vide p. 2 [illegible] 2 12:l. Prolapsis Ani This is a troublesome symptom which sometimes occurs in diarrhoea. The protruded intestine should be immediately replaced. Most writers recommend to do this with a dry cloth, but this will irritate the sphincter ani & make it contract. The smoothest and least irritating article within my knowledge, is the crop of a fowl, or the neck of a bladder, turned inside out & filled with warm water # Afterwards we may apply astringent washes & injections of white oak bark or other similar articles, or of acetate of lead. The latter article may also be given internally in doses of from 1 to 2 grains. It will have a tendency to overcome the relaxation. Astringents are multitudinous & have had a specific [illegible], which proved to be the bark of [?strea] virginica At another time I had a specific sent me which proved to be viburnum sentago all the vib. are astringent Prolapsus ani “The part is relaxed and passes down and is then strangulated by the sphincter. For a permanent cure we must resort to astringents & tonics, but the part must be [illegible] by mechanical means If the intestine is not replaced, [illegible] or suppuration will be the consequence” “Take 1 bladder, cut off the neck, turn it inside out, fill it half full of warm water, and tie up the neck” “This disease was very common at the commencement of my practice but is now rare. The change has arisen in a great degree from the more correct notions respecting the proper management of the mother and child which now prevail. It is possible however that it may appear in [epidemics] and that case we should expect that it would appear for a time and the disappear # It frequently follows other diseases both in children and adults # According to the law of contagious diseases and that it is of no use to prevent it # Heat is a stimulus but too much of it produces a debility which may be [illegible] perhaps in direct debility “Since a free ventilation of nurseries has been practical the disease has been rare. laying aside the use of the preparations of alcohol has also been beneficial.” 13 Aphthae or Thrush White thrush from [illegible] (to inflame) This disease often appears within the mouth is then generally unaccompanied with fever. In some cases it is idiopathic but it more generally is a consequence of morbid affection of the primae viae # It is frequently found in adults of robust constitution which have been very much debilitated by previous that disease infancy and old age are most subject to it & in infants, as was just mentioned it is often an idiopathic affection In some families every infant is several with this affection. The vulgar error however, which very generally prevails that all children have the thrush at some sooner or late period other # is contradicted by the fact that many children as I have known never have the least appearance of it at any time “and it may probably in all cases, be prevented” The most feeble and delicate children are affected with the most violence, hence & from the fact of its being an affection of old age & a frequent sequel of other disease in adults, it may be inferred that this is a disease of debility & this [illegible] will be confirmed by the predisposing causes which we find to be, confined air, a very hot room & improper food# It is caused among the poor by bad air & among the rich by too great warmth & confinement. The fever likewise which accompanies it in many cases is of a typhoid character. # “Caused by neglect of the nurse by want of cleanliness & is often the effect of costiveness” # And have been led to prescribe remedies to prevent the thrush “commences on the inner part of the lower lip & corners of the mouth & extends over the tongue & inside of the cheeks & gums sometimes all these parts are affected & sometimes only one of them” “It appears in small eruptions or vesicles containing a whitish fluid resembling a coagulum of milk these vesicles often coalesce so as to form patches” “extend down the oesophagus to the cardia & here in all known cases it has stopped” Prof. Tully has seen p.m. [illegible] which the thrush the al canal [illegible] “The feces are sometimes covered with aphthous sloughs” “in its severest the eruptions are of a dark brown or deep red colour” “The alvine discharges are very acrid” 14 Symptoms – The disease is preceded by languor and sleeping This is so generally the case that it is common for nurses to say that the child is sleeping for the sore mouth In adults I have observed the same fact, & have predicted the appearance of thrush from the drowsiness of my patient # The symptoms of thrush are very obvious. It commences with white specks upon the lips #, angles of the mouth, & tongue effervescence. # In severe cases the specks in crease in number and size until they cover the whole inside of the mouth the throat & are found indeed upon the stomach x & throughout the whole intestinal canal though this is disputed. One thing is certain, whether these specks or flocculi extend throughout whole alimentary canal or not, viz. that they are found upon the rectum, agreeably the law that the orifices of tubes are most affected The white crust will fall off and be succeeded by one of a darker colour. The coats of thrush are often many times renewed & in this case the formation of a new one is preceded by unusually protracted sleep. A typhoid fever may accompany. It seems to be an eruptive disease determined [illegible] the al. canal. “In its milder form it is confined to some particular part of the mouth or to the mouth itself. The eruption is white & the mouth appears “as if a stratum of coagulated milk were spread over it” & but one separation of the curd like crust will take place. The general health will be but little disturbed” “In severer cases two or three successive crop are formed & the habit being unhealthy, the food innutrient, & the frame weak and atrophous, the under [surface] ulcerates and spreads & a low typhoid fever ensues” # “Your principal object should be to produce an excitement in the bowels by some mild medicine” # Because it is an eruptive disease however diaphoretic seen to be indicated & those which [illegible] action “The treatment is ordinarily a gentle laxative but there is a choice in the kind of laxative. Some practitioners recommend oily medicines, as butter, goose oil, pigs foot oil etc. But these articles do mischief As the vital powers of the stomach are weak, these oils will become rancid” # In such circumstances the oils become rancid & consequently irritate. I never allow oils to be given, yet it is a common practice to swab the mouth with oils, especially goose oil (or [illegible]?) # Chalk shd generally be preferred the other articles dissolve more slowly & may act in part mechanically” 15 It is thought that this disease has often been prevented, by giving soon after birth a teaspoonful of cold water & repeating the remedy every morning, for some time taking care also that the bowels be kept open There may be some foundation for this belief inasmuch as the disease is brought on by heat and debility. “In families where the children have uniformly been subject to this disease. I have recommended cold water as directed that the room should be well ventilated and the child not covered with too much clothing” In mild cases & where the constitution of the child is robust, a gentle laxative will be sufficient to remove the complaint # Castor oil is very often prescribed for it & it may be proper to five it to assist the operation of other cathartics But there are several objections to this article. It does not affect the secretions so much as other cathartics. It does not evacuate the contents of the bowels so thoroughly as others & it tends to # relax the coasts of the intestines, already in a state of morbid relaxation “It will not remove the mucus of the intestines” For mild cases magnesia is the best laxative where it can be given in sufficient quantities. If the bowels should not need a cathartic chalk or some one of the other testacious powders may be given “as [illegible] oyster shells, crabs eyes, crabs claws etc.” # Because it is an eruptive disease however, diaphoretics and articles which translate action seem to be indicated # “Give at first the clear liquor of this infusion and if this does not operate stir it up and give the substance (1) “After the stomach and bowels have been evacuated the ipecac should be given in small doses ¼ to 1/6 of a grain, to keep the bowels open, to produce a tonic effect, to determine to the surface & to prevent convulsion Ipecac has more claim to be considered as a specific than any thing else. It obviates the morbid secretions of the bowels it acts as a tonic never produces unequal excitement or other tonics & it does not like astrigents produce constrictions Whenever there is a tendency to unequal excitement it must be obviated or tonics will do no good” # I rely upon the ipecac though I use [illegible] sometimes especially white root asc. tul. # Indeed “if diarrhoea is present, prepared chalk is a good remedy as is also charcoal: the best form of which is burnt oak for this can do no mechanical injury” # “I have found this almost a specific” Since I have used this treatment I have not lost an infant by this disease” Ipecac in small doses as an alteration approaches as near to a specific in any remedy can # which is not to be expected # Astringents must be avoided, though tonics are indicated because they produce unequal & local excitement & stricture they must be given in the latter stages after excitement has been [equalised] A little borax may be given Moseley’s solut. zinc ziii al. zi [illegible] 1 pt 16 In the commencement of the disease if the symptoms do not indicate the probability of a severe case an emetic of ipecac is the best remedy Antimony has been recommended but it is not a safe emetic for children within the mouth Infuse [illegible] of ipecac in 6 teaspoonfuls of warm water & give a teaspoonful every half hour until the patient vomits or purges. # Ipecac has the advantage over antimony in its tonic and antispasmodic properties & in the mildness of its operation, never producing alarming symptoms # If the ipecac empties the stomach and not the bowels, a blue pill should be given of the size of from 2 to 8 grains. If this be found insufficient, it may be assisted by a dose of calomel, or magnesia or an enema (1) After the bowels have been thoroughly cleansed the ipecac should be given in small quantities a fourth or a sixth of a grain to determine to the surface & to prevent convulsions # If this dose moves the bowels too much, we may add “[illegible] or 1/6” one sixth of a 1/8 drop of Laudanum to each dose The absorbent powder or the white decoction may be given at the same time# Astringents should be cautiously avoided until the stomach and bowels been thoroughly evacuated # “& if there is much fever” Where this has been done we may make use of Moseley’s tonic solution, or cornus [circinata] [illegible] alba, or sericea or saffron safely & with advantage It is to be remarked that chemical action is prevented by the vital principle acting upon the food or articles introduced introduced into the stomach, and putrefactive or [acetous] fermentation if the vital powers of the stomach are [vigorous] This principle applies to vegetables Plants taken up in full blown in August and packed in live [sphagnum] will be preserved by the life of the sphagnum In thrush the powers of life are weakened & not only substances taken in but the secretions themselves are subject to fermentation hance the use of obviating the effects by alkalies limewater magnesia, chalk [illegible] absorbent powders white decoct. Rx. “To prevent the increase of vesicles of effervescences, syringe off the acrimonious fluid as well as you are able, by some diluent or detergent gargle and expedite the separation of the sloughs by invigorating astringents” vide Dr Good vol [illegilble] p. 30 “A little borax & ergot may be put into the mouth. But if the mouth is dry & parched, this and other astringent shd not be used. In such cases we should give mucilaginous substances as gum ar. slip. elm. or sassaf X 5 or 6 gr a drachm? of each in a gill of water # or viola pedata (parsley violet) or comfrey We must be very cautious about administering it to infants 17 To correct the acidity which often attends this disease we may administer prepared chalk or lime water & milk Or Rx magn. usta 10 or 12 fr. elix. pareg. xx gtts water zi given in teaspoonful doses every hour If the stools are watery and the child is robust give coct. ppt # vi gr. cal. 1 gr or the compd powder of chalk in doses of vi gr. or a small quantity fo rhubarb instead of the cal. For watery stools give dal. 1 gr & chalk 6 grs or compd powder of chalk It is too much the practice to scratch or rub off the aphthae in a violent manner with a brush or swab. As well might the cure of any other eruptive disease be attempted by violently rubbing or scraping off the pustules. Rubbing the mouth with a brush or swab until the bleeds is a cruelty which ought to be deprecated Still something must generally be done to the mouth in order to satisfy the importunity of nurses & prevent their mischievous attempts A little borax and sugar X is as safe as any thing If the mouth is dry it may be lubricated with muc. gum arab. slippery elm or sassafras twigs When the mouth is in a very high state of irritation probably a small quantity fo sugar of lead would be serviceable. I have not myself ventured to administer it to infants within the mouth For the proper local treatment of ulcers vide ulceration of the mouth From the sympathy which exists between these parts and the surface, tonics should be combined with diaphoretics I have given [illegible] [has] or [illegible] it is [illegible] observed by tonic and determines to the surface # It is mucilaginous sub-emetic & diaphoretic. It may be given freely as a wash or administered freely internally laxative diaphoretic soothing antirritant “The other [illegible] may be as good” The disease of which we have been speaking is a local disease 18 Ipecacuanha in this disease is emetic, tonic, diaphoretic etc. alterative & since I have used it I have not lost a single infant with thrush The viola pedata (parsley violet in some degree resembles ipecac is its qualities & may be internally administered in its stead # “give a teaspoonful of of the decoction” The peculiar kind of thrush of which I have been treating is a local eruptive disease of infants but as it appears in children more advanced it a critical determination of diseased action. It is not unfrequently a favorable symptom, particularly when it succeeds strong morbid action & [illegible] early in the disease In the latter stages & when the system is exhausted it is unfavorable For instance in hydrocephalus, when the whole mouth will sometimes become sore, and the disease seen to be translated to the mouth “from the brain to the muc. memb” In the latter stages of any disease not so fatal as hydrocephalus it is a very dangerous symptom of exhaustion “In cholera infantum it is a dangerous symptom. [illegible] there is not translation from [illegible] essential part” 18 ½ Eruptions in General Children of all ages are subject to various eruptions These are generally occasioned by the quantity or quality of their food. They are frequently cured by change of diet alone & the greatest attention should always paid to the diet is managing them Oily food particularly nuts, must be strictly prohibited, as they often cause eruptions. I have known some adults invariably affected with eruptions about the lips or other parts of the face after eating freely of walnuts Fish & poke week may likewise [illegible] the eruption We may use the tepid bath for the purpose of cleansing the skin. The frequent use of the [illegible] bath is important especially in chronic eruptive diseases of children & adults vide p. 21 & p. 20 For infantile [illegible] [illegible] p. 1831-2 of Good Case of a peculiar eruptive disease vide [illegible] [illegible] P. 1831 1 [illegible] art. The eruption was periodical, appearing at a certain hour every day At first a light coloured opaque elevation of the skin about half an inch log & a quarter broad like the sting of a bee or wasp. Soon after their appearance blood began to ooze from them & producing a drop which concreted into a scab, & at the end of 3 days fall off 8 or ten eruptions came out daily. Treatment was ineffective until a change of air & diet, which effected a cure “Child 8 or 10 yrs of age about 5 p.m. it would complain of a pain in the face then would appear elevation of the skin to the number of 10 or 12 the issue was treated as if [illegible] bark was tried also nit. sil. sulph zinc. arsenic & other minerals emetics cathartics new diet finally fruit was recom ate freely of oranges & was benefitted. Then change of air & travelling were tried or the first day the eruptions diminished & on the third disappeared In such cases try changes of mineral waters & dieting” 19 Red Gum Allied to thrush is that eruption called red gum The original word was red gown (from a sort of spotted red calico) which has been corrupted into red gum It is called by [Willa??] strophilus intertinctus It is a populous eruption & said to be peculiar to children but this last is doubtful The eruption is sometimes confined & sometimes diffused over the whole body. The papulae rise above the skin are distinct from each other & of a rarely contain lymph bright red colour. The vesicles contain by [illegible] only & terminate in scurf. Afterwards subsequent eruptions makes their appearance. The constitution is rarely affected. Physicians are not usually called unless the nurse is inexperienced Nurses give saffron Some physicians suppose this disease to be the same with aphthae. Dr [Willan] thinks they alternate. Dr Russell remarks “I think that aphthae of infants is of the same nature with those eruptions called red gum & differs in this respect that one disease affects the skin & the other the internal surface of the alimentary canal. Dr [illegible] thinks that this affection, preceded by sickness, arises from causes similar to those of aphthae, such as confinement, heat, irritable state of al. can. indigestion [illegible] If the disease be suddenly repelled from the surface, vomiting & spasmodic affections take place. Hence the European physicians Belonging to the primary [page] Probably the patient was not dieted so strictly as was intended & I recommended change of air Oranges however were beneficial. The was too fond of good living, fond of oily nuts There was a slight reappearance after it but of short continuance It was called [illegible], but improperly The eruption was preceded by a warming sensation of pain in the part. “Red gum is an eruption of fine pimples of a red colour affecting infants [illegible] within the mouth. It is a disease that rarely requires the advice of a physician The cure is much better effected by diet and [regimen] by the exhibition of medicines Still the physician is frequently called in and he must prescribe something if for no other object than to satisfy the friends In order any case give a decoction of saffron & snake root to keep the eruption from [striking] in & keep the bowels soluble with tinct. rhei compd tinct sennae magnesia, or other mild cathartics” 20 caution is not to expose infants with this eruption upon them to a current of cold air, or to plunge them into a cold bath. It is said that fatal consequences have resulted from such imprudence The child should be kept clean & be subjected to daily ablution of tepid water. Particular attention should be paid to the quantity & quality of its food. If the eruption should be repelled from the skin the tepid bath will be the best remedy This disease often occurs within the mouth & rarely requires the attention of the physician. [illegible] tone of the mildest of the eruptive diseases “We may give a decoction of saffron crocus? & snake root to prevent the eruption from striking inwards & keep the bowels soluble by mild cathartics such as magnesia & rhubarb. Still more will depend upon diet than upon medicine. Wine & water or one part milk & three water may be given” [belonging] to p. 18a “In managing most eruptive diseases more attention should be paid to diet than to medicine. In most cases it is requisite that the quantity of food should be diminished. If the food is milk, let it be three parts water, or substitute whey. Infants should take no animal food & no crude vegetables within the year. Oily food and the various kinds of nuts should be prohibited even for 2 or 3 years. A strong child in the country, with abundance of air and exercise might be indulged in such excesses with impunity when a feeble child in one of our cities would be destroyed by them” The eruption is so small as not to be observed It is not my object to treat of eruptions in general with minuteness but to give the general principles of treatment food etc. There are many eruptions met with [illegible] children which cannot be classed or be found described There is an affection of children appearing within the weak, which is not described at all. In three or 4 days after birth elevations of the true skin not of the cuticle upon the hands and arms & various parts of the body containing pus and [illegible] or as large, some of them as ½ dollar high [illegible] [fever] I have seen but few cases they were mortal. The books in such affections direct bark & tonics. The practice proved injurious. The disease as I have seen it has been inflammatory and required antiphlogistic treatment It may however be typhoid sometimes perhaps. If so it should be treated accordingly. I have seen but 3 or 4 cases. There were inflammatory. I prescribed in all these cases & from an analogy more fancied than real, between this & [illegible] Eruptions are generally caused by improper quantity or quality of diet. The remedies frequently get the credit of curing the disease when the amended diet cured the patient Oily & highly stimulating food should be avoided. All the nuts one of the worst is the pea nut 21 Strophilus candidus In this species of strophilus the papulae are larger then in any other of the genus. They are not surrounded with an inflamed base. They are very distinct smooth and shining & appear like little pearls under the skin of about the size of half a millet seed. They may continue for some time. A close examination is necessary for their detection. They appear on the bosom & chest They may accompany other diseases I have seen them accompany cholera infantum in the last stages & considered a fatal symptom [illegible] dyspeptic consumption a dangerous symptom The chest appearing to be covered with an oil surface, looking like particles of water I have seen persons attempt to wipe them off as if water had been sprinkled on the part Belonging to p 18 ½ Apples pears and fruits etc. Cleanliness also shd be strictly practised [enjoined] robust children, much in the open air, may have eruptions about the face mouth etc. with impunity when with the same diet delicate children, much confined, would have fatal eruptions, diarrhoea cholera infantum etc. The appearance of the [former] [have] [illegible] and the parents are often much alarmed. The disease is not dangerous however, & leaves no scar behind A scab is formed & the margin continues to suppurate and matter forms underneath “There is a thin [illegible] discharge from the part & the scab comes off leaving a thing pellucid [illegible]” The disease continues & this film is thrown off & the process is repeated 2 or 3 times It is sometimes occasioned by dentition sometimes it is an effort of the system caused by disturbance in the al. can. “A prejudice sometimes prevails with respect to this disease that it is an effort of nature & ought not to be checked It is a loathsome disease extremely unpleasant to both to the patient and the nurse & if allowed to continue some time it would not be safe to stop the evacuation, at least without keeping the bowels open” Some [Phys.] recommend partic [illegible] as specifics. Cal. or blue pill occasionally may be advantageous Buckthorn has been much celebrated in this and other eruptions It is drastic& hydragogue It is perhaps milder in form of syrup. Many families keep it. Half a dozen berries will operate If there is much plethora, the neutral salts may be given Magnesia also both for the indication & as a corrector I have known the muriatic ether much prescribed, but have not used it much myself, substituting for it mur. ac. as below 22 Crusta Lactea This is the [illegible] larvata of Bateman It appears on the lips, forehead & scalp in small pustules yielding pus, which eventually coalesce & form large loose scabs & perhaps extend over the whole face, down the neck and over the whole body. This eruption never leaves a scar behind it however long it may have continued. The skin is left smooth It is more unpleasant than dangerous, as the children affected with it are fleshy and otherwise health. When it has continued a considerable period of time, we must be cautious of checking it, as it is like a habitual discharge from an ulcer Treatment It is very common to give laxatives, such as syrup of buckthorn, neutral salts, magnesia etc. The sweet spirits of sea salt (diluted muriatic ether) is a very popular remedy. IT is given in doses of from 5 to 10 drops, diluted with water & repeated 2 or 3 times a day. I have seen this medicine given in hundreds of cases & am inclined to think it sometimes of service. It, at least give satisfaction to the parents & does no injury. If there is great irritability give 2 or 3 gr. of cal. with chalk. In cases where I have thought proper to remove the eruption. I have given the muriatic acid instead of ether, prepared in the following manner Rx mur. ac. zi alcohol zi Give [3] drops night & morning diluted with water make [oxyg.] oint. by adding the nit. ac. to lard until decomposition ceases, and the resulting ointment is tasteless. It has about the consistence of wax. Some add sulphuric acid but this is not decomposed & is acrid Sometimes the ointments seem to irritate & then we use [illegible] The best is the sulph. pot. zi to a porter bottle of water. Sulph. of soda does not materially differ, but it is unpleasant smelling like bilge water. In different cases apparently similar I have tried ointment & succeeded in one, but failed in another, & succeeded by waste I was led to adopt the use of sulphuret of potash from the analogy between its solution & the water [of] sulphur springs “We may with advantage make application of dry powders arrow root roasted flower hair powder taking care to give a cathartic when we check the discharge. We should pay particular attention to the diet both of the child and mother making the food weak & [simple] Laxatives will commonly be removed; a little magnesia & sulphur so as to move the bowels once or twice a day “A discharge like this may be checked with safety at the commencement, but when it has become habitual it should not be stopped unless a drain is made & kept open in another part.” 23 For this eruption I have found the oxygenated ointment, very efficacious in removing the scabs & healing the sores It is always safe if well prepared. ‘It is made by decomposing nitric acid with lard’ Perhaps the [citric] ointment (nitrate of mercury with lard) may be equally efficacious, but it is less safe. A good ointment may be made by mixing calomel zii with simple cerate zi or mutton suet zi The sulphuret of potash is one of the best remedies for this & other similar affections Dissolve zii in a pint of water & give a table spoonful night and morning also let the part affected be washed with a solution of twice the strength “It sometimes [illegible] two or three days and [illegible] [illegible]” Some prefer sulphuret of soda sulphuret of lime would also be equally efficacious Such solutions small like bilge water & are analogous to the water of sulphur springs I have sometimes used the sulphuret of pot. as an unguent. Sometimes liquid applications & sometimes unguents will succeed best, & if one fails we may try the other “Calomel ointment may be applied about the edges” If the eruption should suddenly dry up & fever ensue, a dose of calomel should be given & be followed by a few drops of antimonial wine 3 or 4 times a day or a small quantity of ipecac. White hellebore may be given Sometimes the eruption degenerates to a phagedenic ulcer. In such cases I have used charcoal eternally also a variety of poultices. I have seen much The const. irr. may expend itself upon the skin or upon the gland. syst. or upon the al. can. etc. We must be cautious about suspending them suddenly “It is important in all kinds of eruptions to keep the skin clean and soft & to effect this we should prescribe the warm or tepid bath, every day or 2 or 3 times a week. It removes itching and irritation, is always safe and almost always beneficial” May be caused by teething or by food etc. Such things often withstand various remedies & hence are prescribed for very empirically 24 benefit derived from the application of roasted flour. It absorbs moisture & excludes the air Eruptions attendant upon Teething Children are very commonly affected with eruptions when teething. They generally put on the appearance of a fine rash, but sometimes consist of distinct pustules containing matter As they are symptomatic merely, they require no particular attention to be paid to them & will disappear when the teeth get through. The worst consequences might result from their sudden suppression; as if this mode of action by which the system relieves itself from the irritation of the teeth, be interrupted, there is great danger that the system will relieve itself by morbid action of the brain, or other parts more essential to life Eruption resembling the itch Another kind of eruption appears on children of one or two years of age. It sonsists of distinct pustules like those of chicken pock, which form a scab, continue to inflame about the edges & contain a watery fluid It usually makes its appearance in summer & if not cured disappears spontaneously at the commencement of cold weather It has often been mistaken for the itch, and attempted to be cured by [?dock] root, but without success. The sulphuret of potash used as above is a good remedy The tepid bath is apt to be neglected but shd not Dock root often fails in this. It is often very successful in children’s eruptions. It is a very old remedy (centuries) Sometimes goes into oblivion & is again revived Prof. Smith thought most highly of R. patientie 6 feet high in gardens. Woodville mentions R [aquaticus] I know not that either is better than our [common] [illegible] I prefer the [Robtusifoli??] or [horserock] It is acrid and acts well when ext. [applied] and is good int. like rhub. R. crispus also has about the same properties but is milder. R. sanguinea is kept by many for it is as a specific for cutaneous eruptions. called also jaundice root & used in jaundice I have used them all and cultivated than all The leaves of the R. sanguinea have all red veins. You will often have such cuticles exhibited to you in families and be [illegible] of about them. Hence the importance of a knowledge of their prop. I have never known them in any but the children of [foreigners] I am inclined to think the taint may be dormant. The eruption at first resembles what is called “horn pock” “sometimes resemble a [illegible]” The nurse was changed & though the new one was health yet the ulcer appeared on her nipple 25 I think this kind of eruption might be cured by diet and the warm both. In all cutaneous affections the warm bath is very important to relieve the skin from every thing that may obstruct perspiration Eruptions & other irritations of the skin translate action from the viscera. Where irritated action exists in the viscera they are symptomatic Gutta rosea of drunkards is an instance of translation of action from the liver “When a cutaneous eruption appears we may generally apprehend that the al. canal is disordered” I cannot too strongly enforce attention to diet. Nothing will avail without it Venereal Eruptions These appear infants born of parents tainted with syphilis, though they may have no symptoms of it at the time of the birth of the child. Some physicians are of opinion that this child may inherit the disease from its ancestor the parents having been apparently free. The eruption appears in smooth hard, circumscribed elevations of the skin of about half the size of a pea 7 resembling a wart before it has seeds. They continue to increase slowly in size for two or three weeks, & become soft, containing a watery fluid in [honey] like substance Subsequently the skin gets rubbed off & leaves an ulcer with ragged edges & sometimes resembling a chancre which is very difficult to cure. I have known one instance in which the ulcer was communicated from the child to the breast of the nurse. Children affected with this Eruptions sometimes depend upon morbid state of the liver analogous to gutta rosea of drunkards Prescribe to the liver “The disease often proves very obstinate” Mercury does not seem to act as in the primary disease Corr. sub. given in this way is as safe as any other article The bowels should be kept free “I think the sublimate acts more on the skin & is therefore preferable to other mercurials” The plantain was once celebrated for the cure of cut. aff. I have known the plaintain in this way apparently cure after mercurials had failed Still the mercury might have prepared the system The plantain is an old English remedy for bites of spiders etc. It is treated of by Woodville & [Willan] It has as little acrimony I have some confidence in its efficacy. There is an old story about a snake & [spider] I have known nondiscript eruption which had resisted the prescription of several phys. cured finally by diet & change of air 26 complaint have a pale & bloated appearance & the powers of life are feeble Treatment. Change the nurse if derived from her Give corr. sub. in doses of 1/30 or 1/40 of a gr. Give the blue pill in moderate quantities but it subl. is better Give the tepid bath. Try the preparations of iron, such as the mur. ferri, or tartr. ferr. or the alkaline solution of iron. This complaint is not so easily cured as the primary [illegible]. Sometimes it will resist the operation of mercurials & all the treatment for scrofula. In this case send the patient into the country & try simple vegetable articles especially the expressed juice of the plantain (plantago major) externally and internally. It is a popular remedy for poison & is apparently valuable. I have known patients cured by the use of this, and of the air of the country. Still I think its main virtue to consist in its bland & mucilaginous quality [In these cases the whole lymphatic system is disordered & deobstruents are indicated. Now the expressed juice of most green vegetables id deobstruent. For instance the farmers make use of green rye in the spring for this purpose] Perhaps the expressed juice of the green plantain is deobstruent Infantile Erysipelas is an improper name vide Gray [illegible] of Erysipelas Good’s is an entirely different disease and his account will completely [illegible] Corresponds perhaps to the rose of the W.F. Goods account of the rash may do pretty well The infantile erysipelas of Europe described in the books is a different thing # Resembles shingles this is accompanied with fever The primary affection is of the al. can. therefore the attention is not to be directed exclusively to the skin I commences with [illegible] [illegible] you are to prescribe to the fever [illegible] This disease is distinguished by the eruption resembling a rose in the shading off of the colour from a dark rose to a light colour & in the concentric circles As I have seen the disease the rash has appeared in patches about the [illegible] thighs principally & the local affection gave no [illegible] and was trifling while the constitutional fever was severe and dangerous. The fever if not broken up in the commencement will resemble a severe case of [autumnal] remittent I have found no satisfactory account of the disease in the books, not even in the W. P. writers. I have however been informed a conversation with W. Indians that the rose is one of their most severe and dangerous infantile diseases fatal in a week and is treated by a vigorous administration of calomel # I have never seen the infantile erysipelas described as occurring in the European lying in hospitals contagious & terminating in gangrene I have seen common erysipelas upon infants however 27 Infantile Erysipelas The classification of this disease id doubtful. It answers tolerably well to the exanthesis roseola of Good “but [illegible] febrile” there is no species in Bateman & Willan which corresponds to it Efflorescence in blushing patches, gradually deepening to a “dark” rose colour, mostly circular or oval, alternately fading & growing brighter chiefly on the legs with irregular appearance somewhat like concentric circles if the patch is not circular the general circumference This is a disease of rare occurrence with us I have met with three or four cases. It is a severe and dangerous disease, apparently the same with the dangerous rose of the W.F. As it appears with us it is very different from the erys. that described by European writers & which is sometimes epidemic in their hospitals. In children in this country it is generally a disease sympathetic with a morbid state of the bowel The elevation of the skin is less than in erys. of adults the discoloration less deep in colour & the skin though a little tumefied is as smooth to the touch as if not diseased In the cases to which I just alluded, the erysipelas began upon the thighs & extended all over the legs. It was accompanied with considerable fever & a hot dry skin The colour of the efflorescence was purplish rather than red ‘We rarely see watery or bloody vesicles, as in other erysipelas’ I evacuated the bowels thoroughly with calomel (for the sake of the excitement rather than the evacuation) & rubbed the part affected The fever will much resemble that of infantile remittent “The spots are in patches from the size of a dollar to 5 or 6 times as large They are shaded in concentric circles from purple in the center to a lighter colour” “If the disease is not checked there will be increase of fever, constipation and tumefaction of the bowels irritation of the stomach affection of the brain, [illegible] death” Administer a full dose of calomel in the first place and repeat it once or twice. Work off the cal. with other cathartics. The secretion excited by the calomel is what we want. The cathar. subsequently given bring away Antimony in small quant. & nitre may be given until the liver is subdued “When the febrile symptoms run high pulse tense, tongue furred skin hot it is a very dangerous practice to apply discutients applications to the eternal affection Acetate of lead applied externally will probably translate the disease to the bowels” “Treatment I first give colored in full doses to alter the secretions to change excitement and promote evacuation, but do not depend upon it as a cathartic I then give [illegible] or [illegible] & [illegible] etc. to move the bowels I afterwards use the absorbants or alkalies, or ant. or iped. in small doses, as the case may require 28 It is attended with constipation & tumefaction & [illegible] of the bowels; with hiccup & severe fever, & may terminate fatally with severe coma “Pulse small & frequent child dies usually on the 5th or 6th day” “Dr Dewers says that in the cases he has seen the disease was not local but would spread rapidly over the body disappearing in one spot without leaving a trace behind it & breaking out in an other & perhaps a remote part thus changing from one end of the body to the other” Treatment. “Evacuate the stomach with an emetic, as ipecac” Clear the bowels thoroughly with cathartics, for the sake of the impression on the system. Give calomel in a dose of from 5 to 10 grs. If it do not operate within three or four hours repeat the dose. If necessary , work off the calomel with senna (or scammony?) adding aromatics if the stomach is irritable or with castor oil if the senna fails using also some laxative injection & the warm bath to assist. Then keep the bowels open with blue pill & “use some mild diaphoretic as aqua amm.” or give antimony from from 1/20 to 1/16 of a grain Pay little regard to the eruption and direct your attention to the bowels I have letters from physicians who have followed my directions & treated the disease not as a local one but with cathartics which testify the complete success of this plan of treatment. In the W.F. also where the “As palliatives after a strong impression has been made on the bowels by calomel, we may give sweet spirits of nitre, aqua ammoniae etc.” I have tried various either applic. without benefit I have “In those cases when the treatment wa local only the patients have uniformly died. I have not lost a single case to which I was called with commencement. I have conversed upon this subject with medical [illegible] out from the W.F. and find that the practice there coincide with mine” “When called to cases of some standing I have endeavoured to arrest the progress of the disease by a blister as [illegible] in gangrene & in the erysipelas of adults. The disease would extend beyond the blister just as if none had been applied” There is an erysip. affection which occurs about the head of children which resembles that of adults which I have treated with lead water 29 disease is frequent it is treated by the physician with calomel & cathartics. They give calomel 10 gr. & repeat it in 5 gr. doses until 20 gr. have been given I once saw a child with a swelling on one ankle supposed to have been produced by the sting of a bee or bite of a spider, which had resisted the operation of poultices & lead water. I gave cathartics but they did not operate, & the child finally died External applications of any activity should not be used, Still it may be necessary to apply something in order to satisfy the parents. The best will be roasted four “dried [illegible] [illegible]. Warm bathing will be very useful. If treated with lead water & cathartics not used, probably every case would be fatal. I have blistered in imitation of Dr Physick, but never with any advantage ‘If the disease be followed by diarrhoea give absorbents & aromatics such as compd powd chalk or white decoction. If followed by weak pulse etc. give tonics’ I have not lost a case when called early ‘This disease is supposed by some to be hereditary I have seen it affect infants on the scalp when it appeared to be a local affection merely In cases of this kind I have used lead water with [illegible] continualy advantage & without any evil consequences’ Cathartics however should be more or less employed in conjunction “afterward aromatics or tonics as the case may require” ‘It sometimes affects the brain’ [illegible] a more [illegible] or [illegible] intertrigo an attenuation & sometimes abrasion of the cuticle. The vessels forming the cuticle are diseased and the skin is formed in an imperfect manner It occurs also about the nates, [illegible] etc. where the skin folds upon itself & the air is excluded sometimes an acrid discharge Cullen thought it a very thematic affection. The skin looks like a new skin upon these parts. it arises from want of cleanliness & from confinement. The stomach may in a state of indigestion secrete an acid and the skin may secrete an acid. Exercise cleanliness treatment in general of eruptive disease When [illegible] flax they would burn a rag and put it in an axe & rub their finger on to harden the skin when chafed. A scorched rag is beneficial & use absorbent powders first nit. [illegible] might be used keep dry the parts Nurses apply “powder post” which is made by [worms] Sometimes it is a vesicular eruption which upon the head is called [farrigo] & in some situations is called ring worm To the [illegible] or intertrigo occurring in various parts the nurses sometimes apply the membrane from suet which is smooth keep off the air, prevents farther chafing and does well. The absorbent powders as starch alabaster etc. do well 30 Sore Ears This forms a very important subject in treating of the diseases of children. Nature has chosen the part behind the ear for eliminating irritation from the system. Under this head I shall speak of purulent discharges from the cavities of the ears & nose Slight blisters and ulcerations behind the ears of infants are very common & are in most cases, so mild as merely to require washing with cold water weak soap suds & with cold water, & being covered with a scorched rag or with roasted flour, to prevent irritation from the cap Frequently the discharge is acrid & excoriates the adjacent skin. Often a miliary eruption at the part commences the disease & is followed by excoriation Affections of the brain are sometimes relieved by a discharge from this part. The discharge is very important to children in time of teething & when affected with bowel complaints. If suddenly stopped fever may follow with full pulse, tense constipated bowels & fulness of the fontanelles & “often nearly all the symptoms of hydrocephalus” cold extremities Blisters behind the ears will generally restore the child to health When an infant is suddenly attacked with symptoms of hydrocephalus [illegible] disease, enquire whether it has had sore ears which have suddenly dried up, & if so, apply blisters behind the ears, for without them nothing perhaps will cure the new complaint. The same is true of old sore legs stopping of the [illegible] & other charges The theory of this, in all such cases, is the necessity, not The quantity of evacuation will not amount perhaps to more than a teaspoonful & the fullness of the fontanelles [rain] in the head & plethora is not owing to the quantity of fluid. The same plethora, pain in the head etc. will result from cessation of catamena which discharges will not amount to more than a table spoonful So you may bleed to the amount of pounds in cessation of a slight discharge for an old sore leg with out relief. while if you start the ulcer again by [illegible] or [mustard] the symptoms will be relieved Case of a man with ulcers on the legs of 10 to [20] years standing discharge stopped [illegible] pleurisy & aff. of liver the discharge restored by [illegible] blisters caustic etc. cure affected Sulphate zinc 10 gr. to oz or 2 oz may be applied Solution [illegible] sil. is one of the mildest application for irritated surfaces vide infra Oxygenated [illegible] is mildest & less apt to become acrid Sometimes when the aff is of an erysipelatous kind [illegible] relax the parts & are injurious Change the nurse also if necessary If the child is fed upon milk by hand, add perhaps a little magnesia or lime water Similar affections may affect the cavity of the ear & the cavity of the nose. If the cavity of the ear is affected in this way & neglected ulceration is apt to take place & the small bones affected causing deafness. First reject milk & water or carb. soda etc. [illegible] Finally if these means fail use stimulating injections myrrh finally [vit.] sil. In the use of [illegible] sil. external began with 5 grs to the oz & increase if necessary to xv or xx to the oz 31 of the evacuation, as is generally said, but of the habitual action of the system. This affection sometimes degenerates into a very troublesome ulcer, extending down the neck, accompanied with much pain & yielding a discharge so acrid as to excoriate the skin wherever it touches it Deep sores will be formed & the affection may terminate in gangrene & death In such cases it may be proper to apply emollient poultices of bread & milk; to which may be added poppy leaves, or pulverized stramonium seeds or ac. plum. Powdered gypsum is one of the best applications Alabaster gypsum is the finest kind Some apply red precipitate but gypsum is far better. Case in which this alone cured; Another physician advised red precipitate The oxygenated ointment if well made is a smooth dressing for them & is the best kind of ointment, where ointments do not disagree, as it sometimes the case. The bowels should be kept open with cal. or blue pill. It will sometimes be necessary to correct the milk of the nurse by administering magnesia & confining her to a simple diet Troublesome & sometimes fetid discharges on the internal surface from the ear arising from a kind of eruption may follow this eruption & may cause deafness if neglected I have known also the cavity of the nostrils & the frontal sinuses affected in the same manner. A cure may be affected in either case by exciting the discharge behind the ear though it may be necessary to keep it open for some time If this fails use (in addition?) milk & water Milk 2 part water 2 part lime water 1 part Tinct. of myrrh if the discharge is fetid & troublesome a teaspoonful to a gill, as an injection for the ear Sol. nit. sil. 1 or 2 gr to oz. water? externally Be very careful in watching the symptom Case of a young man who had had such a discharge for years checked by astringents [delirius] inflammatory fever ertc. bled cathartics etc. Porrigo galeata ([helvetea]) Cuticles below the scales dotted, shining Said to be contagious. I have never happened to see it so though I do not doubt the fact. I have never seen more than one in a family have it A very troublesome complaint The hair becomes pale, perhaps the roots are affected in which case mercury is indicated. Salivation seems to do no good I have seen it practised without any benefit Recent cases I have cured very speedily with oxyg. ointment. Any smooth substance applied to the part & excluding the air, will often cure as for in stance a bladder, or the membrane of suet what is useful also for [fret] Poultices do well, whether upon this principle or moisture changing secretion When a student I recollect there appeared a strong recommendation of poultices A physician of my acquaintance prescribed a poultice & left his patient. It adhered the hair grew into it and the hard crust formed a helmet indeed. It [was] a long time a period of week, before it was removed When it came off however, the disease was removed! 32 Tinea Capitis. Scald Head porrigo This is a local affection & yet much influenced by diet. Sometimes however it affects the system, or is sympathetic of a general affection of the system. The disease consists of scaly eruptions, eventually covering the head with a hard & generally brownish coloured crust. The hair often comes off. Cleanliness holds of course the first place in the list of remedies; the head should be carefully shaved and washed repeatedly with soap and water. Perhaps as successful a mode of treatment as any will be to shave the head closely and apply a bladder or affect skin in close contact with the skin. It excludes the air. Sulphuret of potash zfs or ai to a porter bottle used as a wash & given internally tablespoonful 3 times a day has cured the complaint in a few days mercurials or corrosive sublimate will be useful, but do not always cure. Sulph. prt. internally zii to lb i [illegible] ext zii to lb is [illegible] The ueast poultice is good, but care should be taken that it do not become dry on the head, which should be first shaved. The oxygenated and the citrine ointments have been found useful, as had also the tar ointment which is made as follows Rx tar ziv wax zfs sulphur zi or is Mercurial cathartics should be given from the first and particular attention paid to the diet. # vide last par. The practice in this complaint has been quite empirical & a great variety of remedies, have been popular. Veratrum viride & v. albus & [apocynum] [androsaem??] olium have used for external washes. Syrup of buckthorn is recommended as a cathartic. Muriatic acid Lunar caustic about 6 grs. to zi of water (rain water) well water may decompose it Decoction of cocculus indica, is given internally & externally. Cal. zii al burnt zfs red lead zfs z6 zifs spermaceti cerate head shaved & washed with soap sude every night and afterwards apply this ointment. It is given by [illegible] & Bates [illegible] & called Diet must be attended to Terebinthinate ointment as tar ointment Tar ointment is made of tar and lard or tar & simple cerate There is no difficulty in the diagnosis of the disease. You will be called to prescribe for scalled head and you will find that the nurses have not mistaken the disease. It begins with small pustules the matter [illegible] which is acrid and soon forms a scab over the whole head. The treatment must be principally local. But mercury may be given occasionally. I have not derived much benefit from the common mercurial ointment. Citrine ointment is good however. Also cal zif lard zi 33 has been used 3 or 4 drops in a wine glass of water Finally the sorts of the various species of dock (rumex patientia, crispa obtusifolia, sanguinea, aquatica etc.) have been much used All the species have about the same properties, being acrid purgative etc. They are given internally as cathartics, & externally applied, made for instance into an ointment, by pounding up the fresh root with lard. The following is a recipe Rx yellow resin zii best ale lb i finest flour ziii mix the all & flour thoroughly together & add them gradually to the melted resin. # The tepid bath may be used when this is used always take care to have a supply both of hot and cold water in order to keep up the proper temperature. Ipecac may be administered to equalize excitement in some cases, & as a valuable substitute for this article we can use the root of asclepia, tuberosa, which is expectorant, diaphoretic and laxative. “Vary the remedies according to their affect soften use decoct. rumex particularly r. obtusifol. called horse dock. It at firs increase, the irritation & secretion. Use it externally & internally” The excitement of the al. can. is affected also of the nervous system Various cutaneous aff. different kinds also of local inflammation, or erysipelatous phlegmous gangrenous scrofulous the inflammation varying according to the constitution scrofulous gangrenous I have frequently heard Pres. Dwight speak of the pain he experienced in cutting his wisdom teeth suffered extreme pain for a whole summer She did not appear to me to look like a person in the consumption I was puzzled [illegible] [illegible] I looked into her throat and mouth and found she was cutting r wisdom teeth # The irritation may continue for mouths, from the pressure upon the gum Those who commence cutting teeth at 10 mo. to a year or even later do not necessarily suffer more Delicate & scrofulous children suffer more 34 Dentition Among the causes of infantile diseases no one more claims the attention of the physician than dentition. The bowels and the nervous system are always more or less affected by it & to this cause we are frequently to refer affections of the lungs of the brain, of the ear, of the skin, of the glands, & of the cellular tissue in general. On this subject there is however a difference of opinion, for it is said by many medical men that children which are healthy # well teeth with as much ease as adults. Allowing for the peculiar irritability of [illegible], no doubt they do, but in granting this we concede nothing, for adults often suffer extremely from dentition. I well recollect the case of a Mrs Waters perhaps about 20 or 21 a married woman and the mother of said to have a [illegible] several children, who was supposed to be in the last stage a good deal of cough etc. had raised a little blood on consumption & upon examination & found was cutting the four wisdom teeth. The gums were divided & antispasmodics administered, when she recovered perfectly. # Case of Mrs Purcell’s child had been sick with diarrhoea and fever for some time a flush of fever coming on every day. I had previously extracted defective teeth from the [illegible] mouth. I now looked into the mouth lanced the gum over a double tooth gave no remedies The period of dentition commences at different ages times in different children, varying from the fourth to the sixteenth mouth, but most commonly in the sixth. The two central incisors of the lower jaw appear about the sixth month and are followed in about a month or six weeks by the corresponding teeth of the upper jaw. very [illegible] [illegible] [illegible] cases I have known a double tooth cut first in others an eye tooth in others all the teeth at once You must always examine to see what teeth are cutting You will perceive the gum swollen and harder Some children are born with teeth but such teeth re merely attached to the gum and are useless and should be removed Sometimes there is too much anxiety about dentition generally however not enough Case of a child mother called me insisted upon # irregular distributions of temperature are [illegible] [illegible] hot 5 [illegible] cold 35 Next come the inferior lateral incisors & after these the corresponding teeth above About the twelfth or fifteenth or 20th month appear the anterior molares & are soon succeeded by the cuspidati those of each kind in the lower jaw cutting through before those in the upper. Next we have the posterior molares. The last molar teeth are not found in the child & hence their name, dentis sapientiae. They appear from the 18th to the 25th year. The above is the order in which the teeth commonly appear, but they often come irregularly, sometimes the lateral incisores, sometimes the molares, & in a few rare instances the cuspidati appearing [illegible] Some persons never have more than two incisores in each jaw Occasionally we meet with families who are said to be destitute of teeth. I have known a family from Charleston, who had this peculiarity. The fact however is in such cases that the teeth exist but not rise above the level of the gums, so that they are not ordinarily seen Such teeth have this advantage, that they are not subject to decay & are also very serviceable. Whenever between the fourth and the eighth 2nd year? month symptoms of irritation exist, the cause of which is not obvious, the state of the teeth must be examined. The symptoms of difficult dentition are fretfulness inclination to bit hard substances, putting the fingers into the mouth, slavering, starting in sleep eruptions about the face & on the scalp, flushings in the cheeks. # hot head pupils contracted sometimes dilated sometimes losing their brilliancy In delicate children the eff. will be more chronic & in vigorous more acute The system relieves itself often by evacuation and this is considered often a good symptom as [illegible] there is a great flow of saliva. The system relieves itself by diarrh. by salivation by sweating [illegible] by every mode of equalizing excitement which is the great principles on fevers & indeed in most diseases 36 and cold feet, irregular paroxysms of fever, remitting fever vomiting diarrhoea irregular & green stools wine small in quantity & voided with pain or in large quantities and of a pale colour bloating of the hand feet and face contracted pupils. All the symptoms indeed of extreme irritation may be met with & we likewise find in many cases a tendency to phlegmonous inflammation suppuration in various parts of the body particularly in the ear. Case of a child who was thought to have an affection of the brain. A tumour was found under the arm. Sometimes dentition is accompanied with phlegmonous local inflammations in different parts of the body & suppuration of the glands about the ar by which relief is afforded Ricketty children cut their teeth more slowly than others but not in general with greater difficulty. The child must be held, and the fingers keep in the mouth to keep it off the tongue # The guard being made with a spring, so that when pressed upon the guard will yield and permit the lancet to descend (in the slit of the guard) 37 Treatment. The first and most important indication is to divide the gums with a gum lancet or other convenient instrument. The operation is not usually painful the child will even press against the edge of the lancet. The relief is often immediate and permanent Some relief may indeed be afforded by rubbing the gums with a hard & polised substance & by giving the child something of the same kind to bit, but the most effectual relief will be afforded by the lancet. The chief difficulty in the performance of the operation consists in confining the child. It may be done while the child is asleep & often without waking it. We must also be cautious not to cut the tongue To prevent this it would be better to make gum lancets with a guard # For the double teeth two incisors should be made & it may be necessary to make a transverse one in order to divide a band of a sort of ligamentory substance which confines the tooth. It is sometimes objected to cutting the gums in particular instances that, if it is done too early, the cicatrix formed by the healing of the incision will subsequently render it more difficult for the teeth to push themselves through This is not true for the cicatrix though apparently harder [illegible] less vitality in it than a part which has not been wounded and will be more easily broken through Solution of continuity is more easily made by disease in a cicatrix than in a part which has not been wounded vide J. Hunger. It is a common maxim that an old scar is apt to break out in to a sore The gums should be divided as often as there are any symptoms of irritation, until the teeth Some other diseased action may exist in the system, and the irritation of the teeth be superadded the lancing will only relieve the latter # For the gums having been exposed for a long time to irritation because [illegible], and perhaps ulcerated and are kept irritated by contact with the hard tooth 38 get through I have repeated the operation three or four times upon the same teeth. In some cases however cutting the gums relieves the symptoms only in part. Indeed the irritation sometimes continues after the teeth get through # “use astringents” If any disease from the causes attacks the child during the period of dentition it will be very important to remove all irritation from the latter source, for otherwise all the symptoms may be aggravated & a disease be rendered mortal which would otherwise have been mild. In children of a vigorous constitution dentition is often accompanied with inflammatory symptoms which require an antiphlogistic plan of treatment. Lancing the gums will then be useful as local bleeding & it may even be advisable to bleed from the arm though a few leeches behind the ear are preferable. It must not be forgotten that in infants, the bowels afford a great outlet to diseased action and to irritation: hence the frequent occurrence of a spontaneous diarrhoea. If the patient is costive or if it has a diarrhoea, a dose of calomel should be administered & if the bowels are soluble a milder mercurial, as blue pill may be given. During the whole period of dentition the bowels should be kept open by such cathartics as the state of the system may indicate, such as magnesia, rhubarb etc. adding aromatics if the system is relaxed and debilitated & chalk if there is acidity If a diarrhoea suddenly stops and vomiting supervenes, externally irritant to the [illegible] [surface] generally, injections, calomel The skin shd be kept moist for diaphoresis is one of the most powerful means of equalising excitement etc. If there is much perspiration you may depend upon op. alone but whenever there is much [unequal] excitement opium alone will not do well and ipecac shd be combined with it in small doses # Also by drafts to the [illegible], by local irritants to the skin generally also keep the bowels from remembering that there is no outlet to the brain 39 and the warm bath are to be used, as has already been mentioned under the head of diarrhoea Another & a powerful mode of equalizing excitement & relieving irritation is by diaphoresis. For this use the warm bath & small doses of ipecac & opium or of antimony and opium. Opium will always be useful to allay irritation & particularly if combined with ipecac or antimony, & always safe when there is no determination to the head Small blisters behind the ears relieve the symptoms of dentition & prevent the disease from terminating in hydrocephalus. # If these cannot be kept behind the ears mercurial ointment or cantharides may be applied to the same part. Nervines may be employed either with our without ipecac During dentition exposure to dampness & to currents of air should be carefully avoided & the patient should be kept warm X summer & autumnal epidemic Indeed the effects of it sometimes continue through the winter The desire often resembles spasmodic cholera in the premonitory diarrhoea & the sudden collapse 40 Cholera Infantum This disease appears in New Haven in the month of July August September & October. It rarely commences until the latter part of July & in October there are few cases except those which have commenced in one [illegible] other mouths & continued until this. Indeed cases are sometimes prolonged till the middle of November Symptoms. It begins in various ways; most commonly with diarrhoea, which may continue for days & even weeks without any very alarming symptoms; At other times times with violent vomiting & purging accompanied with high fever. The discharges from the bowels very much in their usually [illegible] from natural colour [illegible] [irritated] [secretion] appearance. Sometimes they are yellow, brown or green, sometimes in small quantities & slimy and bloody & at others in large quantities & watery, smelling like water in which putrid meat has been washed. Worms likewise may be found in all these various sorts of discharges “dead in the advanced stages” The disease is usually accompanied with great restlessness & often with severe pain, which increases by paroxysms at intervals of from fifteen minutes to two hours The pulse is usually quick and weak, the head hot and the extremities cold. The fever is ordinarily remittent but the exacerbations are frequently quite irregular The disease is attended with thirst often [illegible] and after drinking the child vomits. The eyes often appear languid and hollow During the whole progress of the disease [volvulus] may occur Be on the look out for it “The termination of this disease in hydrocephalus I have reason to think is more rare than is commonly supposed. Many cases of this kind occurring in my practice, I have reason to believe were cases of volvulus Or varying from cholera morbus of [illegible] [remittent] bilious fever sometimes putting in the form of cholera of [illegible] at others that of remittent bilious fever 41 while in other cases they may have an unnatural brightness as in pulmonary consumption indication a high degree of mental [illegible] excitement “of bad symptoms” Sometimes the eyes are half open during sleep, as is indeed the case in various bowel complaints of children when severe we often find the diseased action translated from the bowels to the head and terminating in hydrocephalus. Volvulus also may be another termination. Sometimes the vomiting ceases for several days and then returns, while the diarrhoea continues the whole time Duration As to the duration of the disease, it may be very rapid in its progress & terminate fatally in forty eight hours, or continue for months, & the symptoms may vary very much during the progress of the complaint. A damp hot atmosphere will aggravate all the symptoms, while cool weather with the wind from the northwest will mitigate them. In different seasons also cholera infantum will have symptoms peculiar to the year, varying in this respect like other epidemics Finally when it proves mortal, the child is carried off in convulsions, or is worm out with emaciation & dies with aphthae while in some cases death is ushered in by hydrocephalus, volvulus & other diseases Causes. We may consider the cholera infantum as an epidemic sometimes an endemic confined to a particular season of the year analogous (in its grade of action) to the cholera morbus o f adult “This disease is perhaps most analogous to a remittent bilious fever varied by the peculiarities of the [illegible] [illegible] will see in [Jackson] all that can be said in [favour] of the opinion. The very fact that it is often [illlegible] disproves the opinion besides the fact that the disease does not occur at all seasons during the period of dentition The disease is affected by the state of the atmosphere being much aggravated by a damp state of the air always minded by a cool bracing northeast wind The kind and gentle excitement produced by nursing is important in chronic disease “Children should not be weaned till dentition is complete or till 1 ½ years & in the fall” 42 infantile constitution” Dentition has been considered by some as the cause of cholera infantum but to this opinion I cannot assent thought it is held by Dr Jackson & many of our most respectable physicians Dentition may indeed be an exciting cause; it often aggravates all the symptoms & accelerates the fatal termination yet in the winter spring & months it does not produce the disease of not unfrequently children are affected with cholera infantum without any appearance of dentition Worms sometimes make their appearance during the progress of the disease but they cannot be considered as a [illegible] or cause of it. When they exist during the complaint the irritation which they produce must be obviated by such anthelmintics as are not contraindicated by the state of the system. “I think I have seen the [illegible] productive of unfavorable effects.” The cholera infantum probably arises from the same remote causes as the (cholera morbus) & the bilious remitting fever of adults such as damp hot confined air (which can be counteracted only by exercise in the open air) want of cleanliness & bad diet. Improper food may be both a remote & an exciting cause & the same is true of a bad state of the atmosphere muggy or [illegible] of inequality of temperature & exposure to cold. The predisposing cause produced by these remote ones is debility Children weaned in the spring are mor apt to have this complaint, & do not bear the disease so well as those at the breast. I would therefore advise that in places where cholera infantum prevalent. children should be weaned in the fall 43 Some consider malaria the cause Like dysentery this is a disease translated from the surface to the first passages. The fever is of that kind which Sydenham calls febris introversa the action being of an irritated kind in general & rarely of an inflammatory Commencing at the skin & breaking up the balance of the system by obstructing the perspiration the morbid action is transferred to the mucous membrane of the intestines & involves the liver, pancreas & all the glands immediately sympathizing with them. Indications. The indications are 1st To evacuate the first passages; if this has not been already done by the disease itself 2ndly To translate action to the surface & in general to equalize excitement 3dly To excite healthy secretory action and regular peristaltic motion of the bowels 4thly To avoid the causes of irritation and to remove irritation when it exists 5thly To restore the tone of the system & particularly of the stomach and bowels 1st When the disease comes on like the cholera morbus of adults, the stomach and bowels are sufficiently evaluated by the disease generally when the phys. is called and no evacuation s are to be used. It is to be treated like cholera morbus with aromatics as essence of peppermint, with Laudanum We must be careful not to prescribe for the [name] of the disease nor necessarily pursue the plan of treatment generally proper. Often you will find the patient so much debilitated at first as to require stimulants & acrids When we have the collapse stage and a collapse may recur in any disease then the practice of the nurses is correct in acting on the skin Some recommend large doses of cal. [illegible] much smaller the [common] Dr Jackson recommends large doses common in the commencement. Dr [illegible], 1 gr. doses and salt & water I recommend cal. from 1 to 10 gr Though sometimes small doses repeated may change the secretion better than large, yet often a large dose will operate more kindly, then a small one [which] merely irritates “Dr Dewers recommends injections of salt & water 2 or 3 teaspoonfuls to a gill, instead of cathartics. Repeat the injections till full catharsis is produced the morbid action is changed, by translation of excitement from the stomach & small intestines [illegible] [illegible] with cal. ¼ gr. every [illegible] to alter secretion 44 with counterirritants, as mustard, horseradish & brandy on the epigastrium & abdomen with the tepid bath & with injections of starch and laudanum. But when it attacks with a diarrhoea, accompanied with occasional vomiting unless the constitution is very feeble constitution [illegible] extremely delicate the stomach should be evacuated by ipecac and the bowels by calomel or blue pill To vigorous patients & often give in the commencement six grains & would not hesitate to give 10 grs of calomel & an hour after give from one to ten grains of ipecac according to the age and vigour of the patient for in this way the stomach and bowels are more thoroughly evacuated than by giving the calomel after the ipecac has ceased to operate In some cases a single dose of calomel will thoroughly evacuate the bowels, but in others it will only remove the contents of the stomach and small intestines into the colon & a dose of castor oil must be given or one of senna with aromatic seeds The southern physicians, make less use of cathartics and depend much upon stimulating injection, as of salt & water 3 teaspoonfuls to a gill. This practice does not succeed well with us. They also give smaller doses of calomel. This also I cannot approve for a large dose of calomel, ten grains for instance, will evacuate the bowels copiously and kindly, when small ones produce scanty stools, with irritation of the stomach and tenesmus. I may mention also that the French expectant plan of treatment adopted in Philadelphia will frequently be utterly inefficient. Where excited has not been equalized, calomel or any other cathartic may act upon the duodenum only and not produce Such facts as there have been given rise to the opinion that the disease arises from stricture but then the al. can. may be subject to unequal action as much as the skin # a castor oil with elix. sal. aa zi every 2 hours # Yet this practice shd not be adopted indiscriminately where there is weak morbid action accompanied with coldness of [surface] etc. the exhaustion of cathartics will be injurious This is the most important principle in the cure of diseases Sometimes cath. cure the diarrhoea, where the action is unequal. For instance the lower intestines may be torpid and the feces accumulate, the bowels above may be irritated and a diarrhoea of [small] liquid stools may pass by the feces 45 If calomel or any other cathartic produces watery stools in which are small pieces of feces of an ordinary appearance, and there have not previously been copious evacuations, we may conclude that a thorough evacuation of the bowels has been prevented by a spasmodic action of the intestines which has constricted them in places, & confined, perhaps a large quantity of fecal matter. Indeed this may be proved by the success of the treatment, which should be the administration of a dose of opium with a little calomel to change action followed at an interval of one or two hours by a dose of z ¼ and z ½ castor oil or elixir salutis teaspoonful #. It is of the first importance in all typhoid diseases, particularly in those affecting the bowels, that thorough evacuations should be made # 2ndly so translate action to the surface and equalize excitement This indication will be answered by an emetic at the commencement, as already directed & by small doses of ipecac, repeated throughout the disease, & also by small doses of mercurial medicines opium being conjoined in many cases, as will hereafter be mentioned. In some calls where there is much arterial action antimony is preferable to ipecac & the lancet or leeches may be indicated but such cases are rare This indication is also answered by applications to the abdomen of fomentations, with decoctions of aromatic herbs sinapisms, blisters, burdock leaves, horse radish leaves, ginger in spirits aq; amm or the Ulceration of the bowels is generally preceded by aphthae both are effects not causes of the disease “An [epispastic] should not be applied after aphthae have made their appearance. If the pat. is languid & sleepy we may suspect aphthae.” Diluents may be used Obviating irritation by opium is often necessary to have the proper effect of cal. for instance Give opium first & follow with cal. & often you will succeed in obtaining the effect of the cal. when you had failed before “Ipecac when it acts as a cathartic is more apt to produce fecal stools than any other article 46 terebinthinate oils An epispastic upon the epigastrium is very useful to relieve irritation of the stomach & to prevent ulceration of the bowels and aphthae. The warm bath will tend powerfully to equalize excitement will relieve vomiting, quiet restlessness, produce a uniform perspiration & if used at evening, procure a quiet nights’ rest. It may always be used and at any time, unless the patient is in a state of exhaustion. As a substitute for ipecac, the root of the asclepias tuberosa may be used. It is much used in infantile diseases as diluent, to determine to the surface & to promote expectoration. 3dly For changing the secretion of the stomach and bowels and keeping up a gentle peristaltic motion I have found small doses of mercurial cathartics with ipecac of opium superior to all other remedies. If any article deserves the name of a specific in any disease, it is ipecac judiciously administered in cholera infantum. It relieves this disease with more certainty as certainly as than cinchona does intermittents. It may be observed however that a man successful with one remedy only m ay be compared to a mechanic, very skillful with a pen knife! My method of administering the articles is the following. For a child four months old, mix 4 gr. of ipecac & 5 drops of laudanum in twelve teaspoonfuls of water & give a teaspoonful every fourth or fifth hour & at the same time give so much of the blue pill as to You will know when the blue pill begins to have its appropriate effect by the change in the color of the stools Pills of blue pill may be given without much difficulty to children there is little taste except of the saccharine matter. They may be given in food [illegible] dried huckleberries which I have often called for in the country where there was difficulty in administering remedies. There is often great difficulty with respect to this. A child will often scream at the sight of the doctor Opium to allay the irritation of the stomach and prevent the ipecac from being thrown of Ipecac to equalize excitement & determine to the surface Ipecac also, to qualify the opium # Or if this cannot be done, introduce a paste of opium just within the sphincter # Case of a child in a family where 3 or 4 children had previously died of chil. inf. [Lax] & [illegible] habit etc. I commenced the treatment with the pill and ipecac I treated it mildly giving blue pill instead of calomel N.B. For such cases [illegible] 47 procure an evacuation from the bowels two or three times in [never twice] in the twenty four hours. For a child a year old take twice as much ipecac & laudanum with the same quantity of water and give it in the same way. Sometimes three times the quantity of laud. will be necessary; for instance if the child has been in the habit of taking it or if the diarrhoea is very urgent If the diarrhoea is urgent, it may be necessary to administer injections of starch and laudanum & to apply to the abdomen ginger & grandy volatile liniment poultices or other irritants The enema may be made with three table spoonfuls of flour & about 3 or 4 times as much laudanum as you give by the mouth say 10, 15, or 20 drops. # I prefer flour to starch because the foreign starch often contains acid. The chalk mixture or white decoction may also be used. # “Children of a bucophlegmatic temperament and lax habit are very apt to have this disease & with them I have sometimes commenced the treatment by administering blue pill & ipecac.” The success of this plan of treatment will be strikingly shown by the following case. A child 10 months old was taken sick in this town last summer, with cholera infantum, grew worse and was directed by the physicians to be carried into the country Unfortunately the child was carried to a situation not more elevated than N. Haven & while there its strength decayed and all its symptoms were aggravated. The parents despairing of it recovery returned with it to N. Haven & sent for me with a request that I would do something to alleviate its sufferings On recovery from the disease they usually crave [salt] food and salt is a grateful stimulus 48 I found it in a state of emaciation, with hippocratic countenance frequent vomiting, urgent diarrhoea, with stools fetid, watery and containing some slime and mucus, & leaving streaks of blood upon the cloths. The countenance and gestures, expression of great anxiety, and there were frequent paroxysms of extreme distress. I directed ipecac 5 gr. & laud. 10 drops to be put in 10 teaspoonfuls of water and a teaspoonful to be given once in four hours flannel wet with ginger and brandy to be applied to the bowels & gave 5 oz. blue pill, & ordered the diet to be of arrow root flavored with a little brandy. After the second dose the vomiting stopped, the stools became less frequent & within 24 hours the complexion of the stools was much improved. The next day the same medicines were continued and four drops of the tonic solution with a little brandy and water. On the fourth day from my first visit, the child began to relish salt fish, which was allowed Capt. Dennison’s children To correct fetor in the stools we should give charcoal. Carbonic acid, by injection, is given for the same purpose. The mode of injecting carbonic acid, is to place chalk & vinegar in a bladder, and force the gas into the rectum, as it evolved. “This is recommended. I have tried it but not very thoroughly” But if vegetable food undergoes the acetous fermentation it shd not be used. The putrefactive fermentation however is more injurious than the acetous 49 4thly The most common cause of irritation is dentition The gums should be often examined, & be divided if they appear at all swollen. All kinds of food that is hard of digestion should be carefully avoided though for children somewhat advanced perhaps a small quantity of ripe fruit may not be injurious If the child has not been weaned the milk of the mother will be the best food; for those children’ who nurse are more apt to recover than those that have been just weaned. The act of sucking is highly soothing and gratifying & operates like a nervine medicine. The best food for children that have been weaned, will be arrow root, with a little brandy or wine as a condiment & as a substitute for this & similar articles from the shots, we can direct a porridge made of roasted flour. If in the latter stages of the disease the child craves any particular of food, as salt fish, or salt meat, or wine or brandy, it should be given, & all kinds of medicine laid aside if the stomach leathe3s them; for strong disgust will debilitate by exciting nausea. Frequently however we can succeed in preventing this effect, by a different mode of administering the medecine the sight of the spoon for instance may may give rise to the loathing & nausea. With respect to food we may lay it down as a general rule in such cases that when the powers of the stomach are so weak that food must undergo fermentation in it, vegetable diet should be preferred to animal. For local irritations, various applications should be made & various articles administered, especially in the latter stages “Tea juice? boiled beef a teaspoonful with pepper & salt is grateful frequently & checks vomiting but at first vegetable preparations are better” vide supra The chalk mixture made with a little opium in some cases or with astringents etc. a valuable [illegible] 50 of the disease or when we are compelled to try a variety of remedies. When there is unequal excitement & unequal temperature blisters may be used. Blisters sometimes produce perspiration. To relieve irritation of the stomach effervescing mixtures may be drunk, they are often more grateful. [illegible] we may fill the stomach where there is vomiting and dilute its contents with a tumbler of wine whey I have often succeeded with it with a teaspoonful of aqua ammoniae in it as being thrown up will be no objection. If the disease commences with much irritation in the stomach, it may be useful to overcome it by counterirritation in the rectum produced by an injection of soap suds or of salt and water 3 teaspoonfuls of salt to a gill of water, for a child a year old. Dr Dewers relies must upon this latter article in the commencement of cholera infantum and repeats the injections until the bowels are fully evacuated. He likewise recommends small doses of calomel, a quarter of a grain for instance repeated once in an hour until the bowels are evacuated. In cases of irritation of the stomach & torpor of the liver & portal system, this practice of salt & water & small dose of calomel does well. In chronic cases he gives magnesia rhubarb & opium. With respect to small doses of calomel it may be further observed that they will not answer when the intestines are much coated with mucus & that in some localities they do not answer so well as in other places. On the shores of lake Erie for instance the physicians are obliged to give large doses of calomel than we give There are cases in which small doses seem to irritate & large doses operate kindly “In the latter stages Rx magnesia grs 4 SS gtts Rhei gr i.” C. Florida not so pleasant but loses its mawkish & herbaceous taste by keeping (like peruvian bark) The spiraea is though less inclined to act unequally in this state than most other astringents If one astringent wears out try another Oak barks Rose [illegible] (salix [illegible} “A valuable popular remedy” has mucilage combined seeming to resemble ([illegible]) [illegible] was formerly much used but is now superseded by native articles It is well known that because These astringents are often prompt up is specific [illegible] virginica was specified good [illegible] & [illegible] it e.g. viburn. lentigo, raspberry, blackberry, [illegible] [illegible] root decoction recommended by Dr Rush thought to deter to [illegible] used by many) [illegible] bark has [mucilage] There is apt to be a paucity of [urine] in this disease as well as in Diarrhoea & dysentery and then diuretics are indicated and are highly valuable 51 5th When in the latter stages of the disease the principal indication is to restore the tone of the system & particularly of the stomach and bowels we must make free use of tonic and astringents. Moseley’s tonic solution will be one of the safest and best articles in this stage. If the bowels, by a habitual action keep up the diarrhoea, astringent will be more specially indicated such as the compound tincture of vitriol. I prefer however, the cornus circinata to all other articles C. servicea (red [illegible]) C. [illegible] C. alba nearly allied Of astringent vegetables we can make choice from a great variety which are indigenous & common. All the various species of viburnum all the [potentillas] & the roots of the strawberry to say nothing of the bark of the oak & indeed most of our forest trees, are astringent & may be used The spiraea tomentosa is much used in decoction or extract All the species of [illegible] are astringent & the C. [rivale] is a most valuable article; as is also the geranium maculatum, which may be be given in wine & then we shall have red wine. The sttici limonium (marsh rosemary) is not so agreeable but is frequently more efficacious specially if the mouth is sore. Its taste resembles that of salt mud. When given internally, it is boiled sweetened & has a little wine or brandy added. It is also used as a wash in case of the supervention of aphthae. The erigeron canadense, called colt’s tail & strangury weed has been found a valuable article in the latter stage of this complaint and of dysentery given in decoction. It is acrid pungent like [illegible] bitter & stimulating & acts also upon the kidneys as a diuretic. It seems likely to prove a Give it in decoction or in milk which will cover the taste of it Balsam of copaiba or turpentine cannot be combined with mucilage so thoroughly as in the white pine bark in milk & water diuretic & [sheathing] to the bowels I have often used the expressed juice of spearmint as in diarrhoea q.v. It is important in long continued bowel complaints of children that the medicine shd be grateful The diuretics are useful both in children and adults (dysentery diarrhoea & cholera infant) because there is a paucity of urine and acrid irritating secretions In some cases of exhaustion we give opium constantly in small quantities to keep up the [illegible] Mucilages marshmallows or substitutes for which hibiscus palustris hib. syrica hib. [illegible] hib. (rose of [shora]) Mucilages by stopping irritation are diuretic 52 a valuable article in the latter stages of bowel complaints provided there is not too much vascular action. It has been long used, vide Barton, the N.Y. Medicophys. Transactions etc. In 1790 an itinerant came through N. Haven offering to cure the dysentery; and attracted a good deal of notice. It was found that his [illegible] consisted of this article. The other species of erigeron have similar properties. In the latter stages of the diarrhoea mucilages should be given. They made of any of the various in articles in use, but perhaps the most valuable mucilage, will be that made from the inner bark of the white pine, which will furnish a terebinthinate principle in addition to its mucilage Often in the latter stages of the disease, great benefit will result from supporting the abdomen by a bandage and a plaister of white [diachylon] and opium or a soap plaister (of [illegible] & soap) 2 parts sp. 4 pts plaister In extreme exhaustion & debility from the long continuance of the complaint with cold extremities, aromatics and stimulants may be required & we may give spiced tea spiced wine or brandy in small quantities, or the white decoction and apply cloths dipped in brandy to the abdomen & to the extremities Nothing has more affect upon complaints of the stomach liver & bowels than the state of the mind as we see in dyspeptics The We are apt to suppose children not subject to notice of [illegible] children [illegible] mental impressions. When the matter has been dissolved in grief & abandoned to despair I told them to tray as a last resort carrying the child in a hack out of town the excitability was entirely gone the child might as well die in the back as any where strange advice On the top of the [illegible] about two miles out lifted up the child [sound] trees grass birds, etc. opened its eyes before this had lain with eyes half closed noticing nothing 53 Finally when every form of medication seems to fail, our only remaining resource will be change of air. This is a most powerful remedy. The physicians of N. York and Philadelphia are continually recommending it. We are apt to suppose that in children it can be only the purer air & the exercise of travelling that produces a good effect, when they are carried from home for their health, but on the contrary the change of scene seems often to have a more powerful effect upon them than it would upon adults. Children that have lain sick for weeks, instead of pursuing their accustomed amusement even though mere infants seem of ten to settle into a state of utter despondency from long confinement & the constant sight of the same unvarying objects around them, & appear to loath every thing offered to be done for them. This morbid condition of mind seems to be one directly opposite to that of nostalgia or homesickness & is to be relieved in a corresponding manner. I well recollect a child apparently in articulo mortis cold & vomiting nothing wd [illegible] the vomiting entirely beyond the influence of medicine or food. It was carried in a hack to the top of a hill without the town N.Y. [illegible] where it had a view of the sound, & the scenery of the country around. While there is brightened up vomiting ceased and took food staid an hour or more & then was carried back to town, where it finally recoverd. 54 The symptoms attending cholera infantum very very much and give rise to considerable variety of practice It is probably owing principally to this circumstance more than to any other that physicians differ from each other in their mode of treating it. Post mortem examination show that this disease affects principally the mucous membrane of the stomach & the small intestines; rarely the large ones. Sometimes coagulable lymph is found in the intestines but less frequently than in other diseases. Sometimes the mucous membrane of the intestines is thickening & according to Dr Jackson ulcers are occasionally found both in the small & also in the large intestines. The liver is usually enlarged without derangement of structure Ordinarily the brain exhibits no morbid appearances, unless the disease has made a determination to that part constituting hydrocephalus N.B. The remarks upon asclepias tuberosa introduced under the Head of [illegible] capitis probably belonged here Fever of the bowels Acute [illegible] of [illegible] Different writers give different names and do not always give the same symptoms. The European disease differs somewhat from ours. It is our infantile winter epidemic. Typhus infantum of Prof. [Tully] “Disease of the bowels bowel complaint, plague of the bowels, winter epidemic & [illegible] epidemic. Remittent bilious fever (at south) Musgrave’s spurious [illegible] fever Duncan III or IV” There is some [illegible] action but more of the character of irritation like other infantile fevers Rarely vomiting never diarrhoea in commencement The morbid excitement often extends to the lungs putting on the for [illegible] what is called in adults bilious pleurisy The disease is not common at this time though it was very much so formerly Probably it will return It is almost the only winter infantile disease & so common has it been also that the nurses call almost every disease in winter, of childr, by this name of choler. The dis. is to be broken up in its [illegible] by means various in various patients by a strong impression upon the stomach in a strong constitution but by an impression upon the whole system in the delicate constitution Comparison to a weight upon a [illegible] If applied upon one part only it will break it not if applied to [illegible] It is desirable that vomiting or at least nausea should talk place from the cal. In enteric 55 Constipation with Fever or Remittent bilious fever of children Musgrave’s spurious worm fever marasmus acutis This complaint has been known in N. Haven for more than 50 years by the name of choler. It is called in some places at the “It is unfortunate that we have no better [illegible]” eastward, the plague in the bowels. It is a common bilious “It affects however the duodenum & small intestines rather than the liver” fever produced by causes which operate upon the bowels a part of the system which in children more particularly invites Children are attacked by it from the age of 3 mo. to 2 or 3 yrs. febrile action. It is often inflammatory in its commencement Sometimes it [illegible] in the form of typhus Symptoms The pulse in the commencement of the disease is full, frequent & sometimes tense, the skin is hot and dry face flushed, respiration, short and laborious, tongue covered with a white fur, the abdomen fuller and harder, than in health, & the bowels costive; the urine small in quantity and high coloured & sometimes the fever is attended with cough & expectoration. This disease is a fever which often affects the lungs and always the alimentary canal & liver, the secretions being suspended and the bowels constipated. Treatment. This will be antiphlogistic in the commencement of the fever & the first indication will be to evacuate thoroughly the stomach and bowels. This will best be answered by a single dose of calomel of from 5 to 10 or 15 or even 20 grains for a child from four to twelve months old We shall thus produce a strong impression upon the whole alimentary canal & upon the system at large. In entonic cases and vigorous habits a little tartar emetic may be added to the calomel Usually the calomel excites both vomiting and purging, but sometimes it is retained on the stomach and has no immediate cases it may be beat to conjoin tartar emetic for this purpose. Sometimes the cal acts upon the stomach & duodenum & excites the action of the liver, and spends itself there, without producing catharsis Sometimes it is necessary to repeat 10 gr doses of calomel once in 2 hours until 40 or 50 gr have been given and cause them to follow with liquid cath. a [illegible] or jalap or scammony N.B. If there is great difficulty in giving medicine repeatedly, we may give powder of jalap in coffee or fermented liquor or we may give a teaspoonful of the tincture of (not briony root but pure jalap in milk & water which will not be tasted Feeble constitution must have the warm’ bath. # Rx senna zjs man zi senega zii anise seed zis liquorice zfs [illegible] ½ [illegible] This I have held the child with. remember large doses are needed Rx scamm. grs 2 or 3 chalk & diaphoretic antim. this was called Earl of Warwick’s powder & was kept in the shop here. Tart. emet. would be a more certain prop. of art. It produced violent vomiting. Scammony is better united with cal. however. # # Cautiokn about covering the [illegible] with a blanket vide # Cal. was finally substituted for the [diaph.] ant. This Warwick’s powder used to be a shot preparation in this town and parent would send for it. From the uncertainty of the strength of the diaph. ant. however, [dangerous] vomiting sometimes occurred from the use of it 56 effect. In the latter case a second dose may be given two or three hours after adding from an eighth to a quarter of a grain of tartar emetic for a vigorous patient Fifteen or twenty grains of calomel will often empty the stomach and bowels freely & remove all the symptoms. The calomel may however evacuate the bowels but partially & in some instances not at all merely moving the contents of the small intestines into the large ones. In such cases another cathartic is needed for completing the purgative operation If the calomel appears to have no effect, it should be repeated in 5 gr. doses every three or four hours, the patient put immediately into the warm bath & we should commence feeding the child as freely as the stomach will bear with the following R fol. sennae zfs, mannae zi steep in ½ pint of boiling water & if there is a cough, add senedae zii & rad glycyrrizhe zfs. If the stomach will not retain the mixture of senna the powder of jalap or scammony mixed with tea coffee or milk must be substituted, giving 4 or 5 grains in the intervals between the doses of calomel Injections vide p. should be given to assist the operations of the cathartics and repeated every 2 or 3 hours until the bowels have been thoroughly evacuated taking care however not to commence with injection until the cathartics have had time to operate When we have succeeded in procuring stools we shall find them to consist of viscid green mucus mixed with half digested food. Sometimes in the progress of the disease they exhibit the appearance of small pieces of membrane, of There is a membrane [illegible] inflammation of the duodenum similar to that of croup. This indicated by pieces of membrane preceded however by pain in the part obstinate constipation etc. This is a strong indication for calomel which however will not operate as a cathartic until the violence of the disease is broken Warm bath & injections will also be more particularly In some violent cases of the fever where calomel seemed to have no effect. I have known acid as lemon juice advantageously combined with calomel Among the cathartics and laxatives used in the second stage we have the wild liquorice or [illegible] [circa???] which was formerly a popular article and kept in families. It is diaphoretic and laxative and possesses and also deobstruent properties It is said that with this the Indians formerly [died] their porcupine quills # The acids are sometimes used in combination with mercurials I should not use them unless when mercury fails Sometimes it affects the ear & produces suppuration & discharge. It may terminate in effusion into the ventricle of brain. It may terminate by exhaustion Or may terminate in thrush “in which case there is a double translation 1st from the bowels to the head & thence to the mouth oesophagus & bowels 57 & of about the size of petals of peach blossoms, floating in a liquid of the same colour. Such stools as these latter are a sure indication that a farther evacuation from the bowels is needed vide p. 207 They are frequently evacuated by adults in bilious (or common cholic. If such continue it is well to vary the cathartic and give magnesia, or soluble tartar (peerlash & cremer tart.) or phosphate of soda, or any other neutral salt. generally the violence of [illegible] [illegible] & The blue pill may be substituted for the calomel & given three or four times a day, until the stools change their appearance or the mouth is affected, though this rarely happens to children under four years of age. These stools rarely have any smell & as they indicate a want of secretion I the liver & glands of the abdomen, mercurials are peculiarly appropriate. In some states of fever attended with stools of this kind I have known the free use of acids with mercury very useful # After 48 hours the fever generally remits, and sometimes it continues in the form of a remittent for six or eight weeks or more. Very frequently however it changes its seat in the course of 15 or 20 days & terminate in a phlegmous swelling of some of the glands or in phlegmon or is determined to the head & puts on symptoms of hydrocephalus, which are best relieved by blisters behind the ear, a place which is the natural outlet of diseased action in children. They may terminate naturally by a discharge of purulent matter from the cavity of the ear or fatally by effusion into the ventricles of I recollect two cases early in my practice, which continued 6 or 8 months. They were very violently attacked They continued 6 or 8 months coma Hence we should never despair In the latter stages it may be proper to give tonics or those articles which are called tonic very unlike the vegetable tonics however. They produce a [illegible] excitement Giving arsenic is no new practice It is a safe and efficatious remedy, when the dis. continues as a remittent It comes after cal. & tart emet. producing liquid secretions. If long continued it must be followed by bark to restore tone and obviate the debility caused by the arsenic Arsenic can only be called a tonic as it removes disease. It would never be given as a [illegible] is pure debility # # I have used digitalis, in the latter stages to allay irritation # In many cases the fever continues from habit & medicines have little affect. There will be an accession of fever every afternoon. Here give sol arsen 2 drops twice a day which is a full dose for a child ½ years old If this has no effect give it [illegible] times a day” 58 the brain; in two cases I have known them relieved by a thrush. If the disease continue a regular remittent without symptoms of hydrocephalus, it will be proper to give tonics, such Moseley’s tonic solution or if the fever intermits or remits Fowlers solution of arsenic the latter in doses of two or three drops the former from 4 to 20 drops, 3 or 4 times a day. I have known a child 18 months of age cured in this stage of the fever, in the course o f two or three days by taking 2 drops of Fowler’s solution 3 times a day. This article however is liable to produce edema or dropsical effusion & if it does we must substitute the tonic solut. (beginning with about four drops) or some preparation of bark. The dose of the tonic solution will depend upon the irritability of the stomach If irritable from 3 to 6 drops will be as much as can be borne After the inflammatory action has subsided narcotics anodynes are necessary to remove irritation and to procure rest We may use opium, either alone or better combined with ipecac or antimony # Indeed as the skin is usually dry antimony is indicated in almost every stage. The warm bath also is indicated in every stage except in the low typhus state of the fever when it would be too debilitating. Epispastics & irritants are useful in the progress of the disease, to translate action from parts essential to life & in the last stage also perhaps to keep up the action of the system. They may be applied to the abdomen if it is much swollen to the head behind the ears where there is danger of hydrocephalus & Avoid too much heat to prevent tumefaction of the bowels. Terebinthinates a [illegible] oil may be needed proper If pneumonic symptoms blister etc. “If the lungs are much affected, apply a blister to the chest, give expectorants, and pursue the treatment required in pneumonia. Senega & squills are good, but are too stimulating for the earlier stages liquorice anise” By this disease it is sometimes proper to do nothing and omit all medicines in mania etc. In those cases as I have had difficulty to persuade parent to do nothing. I have applied aloetic plasters to the bowels I think they have produced evacuations injections also can sometimes be given Case of a very [illegible] child [furious] parents passed in review before him with roasted apples pears etc. after 26 hours he snatched an apple relapsed in 26 hours they probably had over loaded his stomach however the same management finally succeeded afterwards of the patient recovered. vide p. [20?] The same season I had 3 or 4 more such cases of mania which required to be cured by fasting 59 a large one to the chest if the lungs are affected. “This disease is sometimes followed by thrush when an emetic of ipecac will have a good effect. If the stools are fetid charcoal should be given. If in the latter stages there should be tumefaction and pain in the bowels, the abdomen should be supported by a bandage. In the latter stages also a decoction of the inner bark of the white pine be useful. It possesses some tonic properties” Sometimes in diseases of children the mind is affected, the patient will take neither solids nor liquids & struggle till it is exhausted whenever an attempt is made to administer any thing. If that is the case in this disease we must use the tepid bath & we may a apply for purpose of moving the bowels, a large plaister of aloes and ginger to the abdomen Frequently this derangement & morbid revengeful disposition (according to Dr Rush an affection of the moral faculty is so great that we must wait even for 24 hours or more without administering any thing. It may require great prudence and judgment in such cases, to satisfy the parents. Before leaving the subject I may observe, with respect to the propriety of the course I have directed in the commencement of the disease, that if the cathartic which we administer first produces emesis we may be sure that the alimentary will be operated on, & also that we often require a remedy more powerful than the disease, just as in croup. “As to diet meat must be forbidden but sometimes salt food is craved. The weak chicken broth is good. The dis. is something very rapid & violent Fever as violent as the constitution could bear Collapse from the violence of action Parents considered the patient & dead After the mustard was applied as soon as the skin was reddened a blister was applied, which produced a sore 2 or 3 months in healing “In one hour pat. revived” Nervous system affected Irregular action such as after collapse of cholera Strong clonic spasms once in 15 min. “Pat. kept under a constant [narcosis]” Antispasmodics & tonics finally In two or three weeks [illegible] recovered some strength It was called the child that died & returned to life again The above is account of the disease as it most commonly appears. It is different however in different years sometimes effecting one part of the system sometimes another A practitioner keeps this [illegible] [illegible] 60 Case of a female child 2 yrs of age. The disease ran the most rapid course I ever witnessed. The whole system became affected; the pulse was full & frequent, the skin hot & the tongue furred. In 24 hours the disease came to a crisis and exhausted the excitability of the system; the pulse grew faint, the skin cold and the respiration languid the patient became insensible & was apparently dying sinapisms were applied to the abdomen, ankles & wrists & heated bodies put into the bed, to restore warmth. After the sinapisms had been on an hour and excited some redness, epispastics were applied in their stead. Ammonia & ether were put into the mouth & caustic ammonia was applied to the nostrils to excite Inflammation so as to blister. Ether was also put into the mouth In about two hours the system was resuscitated. Immediately a train of most violent nervous symptoms followed the chill became convulsed almost instantly. After trying antispasmodics in vain the convulsions were checked by laudanum, 6 drops, every two hours. The laudanum lost its effect in two hours & needed to be repeated. The blister on the chest produced a deep ulcer which was difficult to cure Finally tonic solution was administered. The child recovered Child of Mrs “Moulth???] Child of N. Beers’s vide p. 208 diseases and consequently meets with no new disease For they do not make sudden transition as in botany plants he is guided by symptoms & by the operation of remedies Appendix to Mes. fever acute marasmus This disease sometimes appears in an acute form with great irritation Sometimes terminates in hectic Patient will run down very rapidly [illegible] appearances enlargement & [illegible] of mesenteric glands “Called” consumption of the bowels” or Marasmus” Mesenteric fever is thought to terminate in hectic Probably it does especially in scrofulous patient and in those bad cases where the tubercles with a mesentery ulcerate “The pain in the bowels is no usually very severe but of a continued aching kind generally better removed by [camomile] injections than by anodynes” 61 Mesenteric Fever Marasmus tabes [illegible] [illegible] This disease arises from obstructed glands in the mesentery & is accompanied with morbid secretions of the stomach & liver bowels. It is sometimes the consequence of some other fever. It is often connected with scrofula, & it is apt to be attributed to worms. The disease attacks children of from two to ten years of age. Symptoms. The fever is of the intermitting remitting kind, with irregular paroxysms attended with tumefaction of the abdomen, costiveness, indigestion, loss of appetite & very irregular appetite & with paroxysms of pain in the bowels. The patient complains much of its bowels, but the affection seems to be rather distress then sharp pain & is neither constant nor regular. The countenance is very pale except when the cheeks are flushed with fever & the limbs are emaciated This is generally a chronic disease, but sometimes it is acute, & exhibits strong marks of irritation in the system. It may terminate in hectic. Dissections exhibit an enlargement of the mesenteric glands. Causes. It is sometimes as has been said above, the effect of another fever. Among the poor, with whom it is most frequent, it is caused by coarse and unwholesome diet. Children born of scrofulous or gouty parents are more subject to it & hard labor by the mother during the period of gestation may have some influence in predisposing to causing this disease in the child. Patients in this disease are subject to paroxysms of pain 62 The indications are 1st to empty the bowels and to keep up a gentle peristaltic motion in them 2nd to change the secretion of the chylopoeitic viscera. 3d to remove paroxysms of pain 4th to remove the obstruction in the lymphatics. 5th to impose the digestion & to invigorate the system generally 1at To move the bowels and keep up a gentle peristaltic motion mild mercurials as blue pill or calomel & chalk should be given & at the [illegible] time friction as in almost all chronic [illegible] complaint should be employed, upon the abdomen, and persevered in by the attendants. A very good mercurial preparation, will be a pill of four parts gr. blue mass and one 1 or ½ gr of ipecac adding a little opium ½ or 1/8 gr of the bowels are very irritable. If this preparation is not sufficient calomel may be substituted in a dose of 4 to 6 grains. The tincture of rhubarb has in some cases answered well as a laxative & corrector combined with neutral salts and aromatics 2nd For changing the secretions, we must rely upon the articles just mentioned, and also upon those to be mentioned under the 4th head 3d For alleviating sudden paroxysms of pain injections of a gill or a half pint of camomile tea have been found serviceable. If these fail give a camphor injection The pain is relieved by opium plaister There is but a small quantity of iodine and [illegible] effect appears to be produced than shd result from the small quantity of iodine Neutral salts in connexion with tonics have undoubtedly [illegible] deobstruent powers 63 4th For removing obstructions of the mesenteric fluids burnt sponge has been thought very efficacious. I formerly questioned whether it had any superiority over soda. Now it is supposed that all the virtues of the article are owing to the iodine continued in it. It would probably be [illegible] better better to give tincture of iodine in doses of 2 or 3 drops. Still the burnt sponge containing carbon & alkaline matters may have peculiar properties The neutral salts given with tonics have some influence in removing these obstruction It has been proposed to use mercury by injection for this purpose. I know not that it has ever been tried For the indication I have been in the habit of employing the muriate of lime & here given it in connexion with the mercurial pills mentioned under the first head It may be made by adding muriatic acid to chalk or marble & the dose for a child of 3 or 4 years, should be from 5 to 50 drops, given in tea coffee or milk. It is best to begin with a small quantity, say 3 drops & increase by one drop at every dose until the stomach is offended remembering that the stomach bears the article best if much diluted. The muriate of barytes might be used; also the carbonate of barytes is used in dose of but 2 or 3 grains, it being a powerful article. But iodine is probably the best article that we know of Other articles containing iodine, have been used besides burnt sponge, as [fucus] [nodasus] & vesiculosus [reckoned] vide scrofula mur. [illegible] dose 4 or 5 drops in milk & water for a child of 3 or 4 years increasing to 50 even 100 perhaps This [illegible] is not to [illegible] [illegible] it iodine as to be substituted by the latter We are apt to neglect an old remedy as a new one comes on The tepid bath shd not be used when the system is too much debilitated It excites the action of the mucous membrane and of the skin not affecting particularly the blood vessel add a little spirit to make the opium [illegible] if necessary 64 Muriate of lime has the important advantage of exciting the action of the skin which is generally torpid. Hence also the tepid bath has been used with success in this disease The flesh brush too if thoroughly applied several times a day will have a powerful effect. 5. To improve the digestion and invigorate the general system Carbonic acid is a most grateful stimulant to the stomachs of patients in this disease. Hence soda water and other effervescing mixtures, may be recommended spruce bar also & similar articles, if they agree well with the stomach. Aromatics as ginger & spice may often be added to them with advantage Among the tonics which are used to invigorate the system. Iron is very often employed & frequently with good success. The mildest preparations least irritating are the best, such as the tincture of the muriate, the martial flowers & the alkaline solution. Still iron is apt to cause irritation Cold bathing is a good remedy for invigorating the system but if the patient is much debilitated, a cordial should be administered previous to using it When the patient is much debilitated I have found anodyne plaisters upon the abdomen give great relief (where opium did not agree) I have used Noel’s plaister (similar to dyachylon) with soap mix opium zii with zfs of this plaister & spread it sufficiently large to dover the whole abdomen Children are very fond of potatoes but they should not be allowed, unless cooked so as to be dry and [illegible] and then thoroughly mashed Some vegetables as spinach, [illegible] & asparagus may be allowed but only in moderate qualities Preparations of meal of [illegible], especially fried, are bad Rx dough roll it in flour and then cut into thin slips, twist & bake them for [some] hours An excellent preparation for dyspeptic batter than crackers called twisted bread In making broth avoid adding rice, flour, etc. which will make the compound approach the nature of pastry and be more indigestible. Make broths as simple as possible & season with pepper & salt 65 Under this head may be ranked the use of the terebinthinates which have a valuable effect upon the mucous membrane of the alimentary canal The best article is a decoction of white pine bark, which is milder than any preparation of the turpentine of the shops Regimen. Flannel should be constantly worn next the skin to keep up an action in it. The patient should take exercise in the open air whenever the weather is good & damp easterly winds should be carefully voided as they have great influence in all chronic affections particularly glandular of the bowels. Friction & cold bathing have been already mentioned. Diet. This should be carefully attended to Raw fruits, potatoes and other garden vegetables, corned beef & in short all articles which are not of the easiest digestion or which have any tendency to ferment & become acescent in the stomach should be forbidden & caution should be enjoined that the stomach be not distended with liquids, so as to interrupt digestion. The diet should be dry consisting of toasted bread & farinaceous vegetable substance, as arrow root etc. well boiled & seasoned with a little wine & spice. If meat be given it should be broiled & eaten, with condiments. In some cases a piece of lean beef that has been partly broiled & then boiled, makes a broth that is grateful & sits well on the stomach. But if there is much dyspepsia, broth of any kind a not good If this fever terminates in hectic the mineral acid shd be used Undoubtedly however the affection may be produced by excessive purging vide next page low states of fever in adults also for the state of the bowels occurs much oftener than some phys. are aware of “The gases may arise from the ingestion, from a fermentation of the natural secretions, or, as I think from a direct secretion of gas by the intestines. this alone would see to account for the rapidity of its production” sometimes small watery stools 66 Tympanitis In diarrhoea dysentery & constipation with fever & typhus fever after these diseases have passed the first stage, the bowels of children affected with them, are liable to be affected with tympanitis. a troublesome symptom This state of the bowels may occur of itself about the time the febrile action begins to subside, or it may be brought on at an early period by the use of astringents, or by heat produced, either by too many bed clothes or by hot articles applied to the body for the purpose of exciting perspiration it is important to examine daily the state of the abdomen in children affected with bowel complaints, that a tympanitic state may be obviated, as soon as it begins to appear The abdomen is [swollen] and elastic to the touch feeling tense like a drum head under the fingers We can tell as soon as the hand is applied whether the swelling proceeds from inflammation, or from imprisoned air, for in the former case the pressure will cause pain The proximate cause of this state of the bowels I believe always to be a relaxation of the villous coat of the intestines & a deficiency of peristaltic motion in consequence of both which the villous coat falls down & forms a valve which confines the gas, while at the same time there is a morbid secretion of all the chylopoeitic viscera which [illegible] the evolution of the gas In the first stages of tympanitis, the alvine discharge usually cease even if there had been diarrhea & dysentery before & the little patients exhibit signs constant [illegible] not acute pain of great uneasiness from the unusual distention of the “It is thought by some that tympanitis is always occasioned by bad treatment in not giving cathartics enough at the common [illegible] Such persons probably do not examine the abdomen of their patients with sequels of severe bowel complaints. Tympanitis comes on whether cathartics have been used or not and nothing is more likely to bring it on than an excessive of cathartics at the commencement of the disease” The temperature had been raised above it secreting [illegible] & the child might have died “I am very partial to diaphoretic measures in general but must confess it is often abused If carried to excess it rapidly exhausts the patient also if excessive heat as aplied and the pat. does not sweat.” 67 bowels. In the progress of the disease tympanitis the child frequently comatose. The tympany is not always to be regarded as a dangerous symptom it sometimes indicates a favorable crisis, yet if it is accompanied with coma, there is danger that the brain may become seriously affected. If symptoms of congestion in the thorax exist, the disease of the thorax should claim our first attention, and the tympanitic state of the bowels be treated as a [illegible] complaint Treatment. The indications are to evacuate the flatus and excite healthy action of the viscera of the abdomen If the disease has been produced or aggravated by heating applications too many bed clothes or too confined an atmosphere, the heated substances should be removed, the bed clothes thrown off & air admitted freely to the patient. In the summer of 1814 I was called to a child sick with dysentery whose bowels became extremely inflated in consequence of filling with the steam of boiled potatoes in [illegible] the bed in which he lay The child because if much [illegible] & [illegible] was so difficult that it was thought to be dying; but upon removing the potatoes throwing off the bed clothes & opening the doors, the symptoms were at once amended & in the end the disease was completely removed by the use of a little [cajeput] oil in water and laxatives For removing the flatus of the bowels we may use enemata of the decoctions of aromatic plants or suds, such as catnip, camomile; the seed of fennel caraway or masterwort seeds or the essential oil of such suds may I prefer camphor to any other articles 3 or 4 [illegible] IN colicky complaints etc. I have known more benefit [illegible] injections of camphor in milk & water than from any [illegible] articles and that too after the most violent purgatives had vailed. I know of no article which operates so well in relieving irritation of the pelvic viscera [Anodyne] balsam Rx vol. [lin] zi [illegible] camph “Sometimes blister the abdomen” 68 be injected in milk and water. But I think I have experienced the greatest benefit in the case of children from the injection of a teaspoonful 2 or 3 of the tincture of asafoetida in a gill of warm water. It unites more readily with the water of a little milk is added A pipe of ivory or the pipe of a common injecting syringe may be introduced into the rectum as is recommended in hysteria, for the purpose of evacuating the flatus. I have sometimes used an elastic catheter with success The peristaltic motion of the intestines is to be excited and healthy secretions induced For this purpose we are to apply friction with dry flannel to the abdomen and mild cathartics are to be given. The latter may be jalap aloes rhubarb etc. with castor oil to work them off If frictions do not succeed, we may apply volatile liniment camphor, oil of origanum & finally epispastics We may likewise give internally cajeput oil in 3 or 4 in sugar oil of mint, oil of caraway, asafetida zfs to si etc. which is [illegible] to offer [illegible] its stomach & is not offensive to the taste and magnesia with [illegible] & cubebs [illegible] [illegible] or guaiacum Dr Good classifies [worms] according to their locality yet he makes mistakes as to their locality Much has been under the subject, and the remedies are almost innumerable. It is rather difficult to select the most important parts of the subject 69 Worms This subject naturally follows that of bowel complaints From testimony which cannot be invalidated it appears that worms of various sizes and forms have been found in almost every part of the human body. It is only in the alimentary canal however, that they occur with any frequency and give rise to symptoms, from which we are led to infer their presence Those worms which are of anomalous kinds, or are found in anomalous situations (oftenest perhaps in the lungs & frontal sinuses) as they are of rare occurrence & as the indications of their presence were either very obscure or altogether unknown wanting are interesting only as curiosities and will be passed over, without any notice, except an occasional reference to the fact known with regard to them “Worms in the alimentary canal are so common, as to have given rise to a class of diseases called verminous & a class of therapeutic agents called anthelmintics. The kinds of likewise of worms which occur in this part of the body have been thoroughly investigated & we are in possession of a large mass of information upon the subject I shall consider this subject under the following heads 1st The kinds of worms found in the al. canal 2nd their origin & that of worms in general, found in the body 3d the general effect they produce on the system & the general symp 5th the morbid effects produced by each species, with their treatment 4th the general treatment of verminous diseases 70 II. The genera of the common intestinal worms are three; toenia ascaris & tricephalus Of the tania there are two species. Tania solum or cucurbitana & t. lata or vulgaris. Of the ascaris there are also two specis of a. vermicularis & a. lumbricoides. 1st Tania This a long flat worm varying much in breadth and thickness which is formed by a chain of flat articulations, united by a border or edge. The accounts of the length of this worm are almost incredible from thirty to a hundred feet. Taenia solum (called also cucurbitina or gourd seed worm & the armed taenia) is distinguished by having the head forked and surrounded with papillae or long fangs (holders) by which it fastens itself to the mucous membrane. The broken off joints have when discharged the appearance of gourd seeds. hence its name of gourd seed worm. Taenia bata (or vulgaris the unarmed taenia) has an external form like a ribbon joints scarcely perceptible & is white and seen transparent. The head is narrower & smaller & the papillae not elongated 2nd Ascaris vermicularis & a lumbricoides The first, a. vermicularis (thread worm, pin worm & when existing in number called ascarides) is filiform, slender at both ends & from half an inch to an inch in length & of the diameter of a small thread found generally in the rectum & though not confined to that part of the intestines. It feeds on the mucus of the intestines & produce its young in immense quantities. It is found in the stomach & called maw worm 71 Ascaris lumbricoides (or [illegible] long round worm) is perfectly round & from four to ten inches in length bearing a striking resemblance to the common earth worm It is said sometimes to perforate the intestine with its mouth 3 The trichocephalus now called [tric???] is a small capillary worm from an inch to an inch & a half or two inches in length. The body is about half an inch in length & Is terminated a tail which is twice as long & end in a fine hair-like point In addition to these worms have been reckoned two others the vesicularis & the gordius. The former is a small vesicle found in the brain (sometimes in great numbers) & containing many small worms. It is now considered a hydatid & is excluded from the subject of worms & verminous diseases The gordius (horse hair worm) is found in soft stagnant waters from four to six inches long & twisted into various knots & contortions” Good. They are sometimes found in the earth in great numbers they turn black on exposure to the air & resemble horsehair, hence their name of horsehair worm They are very common in our vicinity They are rarely found in the human stomach. I have known them coughed up in abundance from the lungs; when they had probably come from an abscess in the liver. It gives rise to a severe disease among the [lapladens]. Vide Good. The maggots of the common house fly & the’ larvae of many other insects, have occasionally been met with in the alimentary canal of the human body vide Good What were formerly called vesicular worms are now considered as hydatids. [Brera] or worms recommended An attempt has lately been made to revive the doctrine of [equivocan] generation. The learned advocate has attempted to fortify his opinion by the analogy of vegetables. But where the experiment has been made the seeds of the forest trees that come up as [illegible] may be found at the roots of the young trees Hyoscyamus formerly was common here but is not now However when the gourd is broken in the college yard Hyoscyamus springs up. It has also in the soil brought from a cellar in Chapel St. Leeches & a variety of insect are undoubtedly taken in in water etc. In Duncans [illegible] we shall find an account of a number of caterpillars [illegible] by a child produced by eating cabbage leaves I think I have never known an instance of worms in children while nursing 72 II II. The origin of worms in the human body Worms arise from eggs. Some multiply by depositing their eggs to be afterwards fecundated by the male. Others are propagated by copulation between the two sexes While a third kind of the taenia fecundate themselves. I have spent much time in investigating the origin of worms in the human body but must confess that I cannot satisfy myself upon the subject. It has been supposed that worms found in the human body are produced from eggs deposited by flies about the rectum, at the time of going to stool. Were this the fact, they ought to be more abundant in summer than in winter, while the reverse is the fact. I am inclined to think that the rudiments of worms are contained in certain kinds of food as apples pears, cider water & unboiled fruits and vegetables. In infer this from the fact that worms make their appearance, oftenest when such articles have been taken & disappear when they are avoided. If confirmation of this view of their origin we find that children are rarely if ever affected by then when under three months of age & seldom while they are nourished from the breast. For though some have asserted that they have seen worms in the bowels of children within the mouth & even before birth yet the fact is not well ascertained. Breras opinions, also adopted by Good speaking of the fluke worm There is no doubt of the fact of worms within [fetus in uteri] 73 Brera thinks that the minute eggs of worms are absorbed into the circulation He says “when we consider that the eggs of worms are so small that they are not perceptible by the microscope of Hoffman and these eggs themselves are masses of small eggs, nothing is more probable than that the eggs of worms are absorbed by the lymphatic vessels, pass in to the circulation pervade the system with the blood & are deposited in the various parts of the body, where they enlarge and unfold themselves when circumstances favour their development.” If worms are found in the foetus, the fact will favour this idea that the eggs of worms are carried into the circulation. It may be remarked also that the parts of the body which favour the development of their eggs are those abounding with mucous The hypothesis of equivocal generation is neither specious nor probable. It derives no support from analogy aid from reason, nor countenance from fact In its operation it is worse than useless as it tends to obscure truth by substituting conjecture while it disregards with the most vague and licentious imagination the boundaries between the animal and numeral kingdom & ascribes to chemistry what pertains only to animal life When the creator first gave being to the natural world, every part of the vegetable and animal system was brought into existence by an extraordinary exertion of productive power. They were not moulded by the slow operation of time & the cooperation 74 of mechanical and physical forces, but he spake and it was done. But since that first act of creative power, we find are that these creatures are propagated and perfected by processes more gradual successive and [operose], many of which may be traced by human wisdom and admit of being regulated and controlled by human culture & ability Rosenstein says “from the eggs of a fly proceeds a fly, from the egg of a hen a pullet and not a serpent, from the egg of a goose, a goose and not a fish So from one worm is produced a worm and nothing else” II II II. The effects of the presence of worms in the body When the seed of worms are once developed in the human body, the health is more or less affected, and the morbid symptoms which then appear are in proportion to the number of size of the worms the sensibility of the part they occupy and the general morbid diathese which takes place at the time, whether the cause or the effect of the worms Worms in the alimentary canal are less frequently the original cause of diseases than is generally supposed, inasmuch as in many cases of disease where they exist, the disease was merely aggravated & not originated by the worms & all the symptoms of worms from which it is common to infer their presence, may be occasioned by 75 undigestible substances for a diseased state of the bowels Worms are often also found to have existed & that too in great numbers, where the general health has been apparently good. I well recollect the case of a child in North Milford who fell from a height & was taken up in a state of coma from the concussion. A dose of calomel was given him which brought away twenty or thirty large worms. The child had been healthy to all appearance previous to the accident. Some physicians go so far as to say that worms are necessary for the health of vigorous children that they are nature’s scavengers a natural provision to destroy the superabundance of food taken into the stomach. Dr Rush was of this opinion. The opinion supported by Dr [Parr] It is a fact beyond controversy that very healthy children have worms with out manifesting any symptoms of their presence until the supervention of some other disease causes them to make disturbance in the system. It is but seldom that they are the excit. cause of dis. The following are some of the ways in which worms are injurious to the system. They may be injurious from their number obstructing the bowels and consuming too much food. They are particularly hurtful by the irritation which they produce when the irritability of the bowels is excited by fever. They sometimes threaten suffocation by rising in the oesophagus & in one instance a single worm I have known to lie in the fold of a volvulus of the intestines so as completely to obstruct the passage 76 Linneus attributed the dysentery to a worm or insect [illegible] dysenterical [languis] the measles to a similar origin. Various authors the itch, sigler, petechiae lusitanus the syphilis martin the elephantiasis nyander, eruptive & contagious diseases in general lancissi, plague, remitting & intermitting fever considering miasm [it] being a collection of insects # some authors, toothache Dr [Adam] observes cancer itself is nothing more than an animalcule a worm or an insect. It would seem from such speculations, that a great part of the diseases which flesh is [illegible] to result from a superabundance of vitality and that as Good remarks in his [illegible] corruption is no longer the triumph of death over life, but of life in one form over life in another. Such fancies lead into the wildest speculations of equivocal generation & relinquish all principles & all limits in natural history. # Vide N.Y. Rep. about the year 1815 77 Symptoms of worms. Those children are most frequently troubled with worms whose powers of digestion are weak. The symptoms of the presence of worms in the alimentary canal are very equivocal, for they may all proceed from other causes. They are countenance pale or flushed sad and dejected livid around the eyes, eyes sunken eyelids swelled pupils dilated itchings in the nostrils, head ache after taking food, mouth water [illegible] filled with saliva, breath fetid, great thirst, grinding of the teeth in sleep, starting in sleep fainting vertigo, palpitation of the heart, irregular pulse & cold abdomen bowels flatulent costive or loose colic throbbing in the bowels severe from [illegible] the small [intestines & umbilicus] appetite irregular & craving loss of appetite pain in the stomach when empty, which is relieved by food urine increased or diminished turbid and milky, stools irregular, containing much mucus nausea & vomiting Sleepiness particularly after eating, bloated countenance swelled nose & upper lip, paleness of the lips, irritation about the mouth, rubbing the nose, itching at the anus irritation about the neck of the bladder dry & convulsive cough difficult respiration sense of suffocation paroxysms of suffocation body emaciated frequent flushings of fever with irregular pulse convulsions, epilepsy and partial palsy. Of course these are not all present at any one time Chorea catalepsy & epilepsy are produced sometimes, by worms Dry convulsive cough Diff respiration In addition to the other symptoms there may be these of irritation of the lungs producing cough also irritation of the brain [772] It will be impossible to class all the articles inasmuch as we do not certainly know the modus operandi of many articles which yet have sustained their reputation for [illegible] Much stress has been laid upon the operation of cathartics in evacuating the [illegible] which the worms generate by their irritation, just as irritation in the lungs produces [illegible]. But then the [mucus] although it forms [illegible] for them, an effect more than a cause, and the worms will make [mucus] enough for themselves Probably many caths act by their acrimony upon the worms themselves. Others by the violence of their operation dislodges them. “Aloes are beneficial in mild cases as a tonic when there is no excessive irritation. If there is excessive sensibility & irritability they are improper as they irritate the rectum they may be given by injection When there are symptoms of worms though no worms exist aloes are serviceable in the form of elxiir prop.” 77:a. IV. [general treatment] In the treatment of patients afflicted with worms two general objects seem to have been pursued both in popular practice & in that of physicians 1st to destroy & expel the worms themselves & 2d to obviate their effects upon the system & at the same time by the improvement of the general health of the patient, prevent their recurrence and increase This second indication will often coincide with the first, inasmuch as a diseased state of the body is the most favorable for the multiplation of worms Of those remedies which destroy or expel the worms themselves we have three kinds 1st those that expel them by strong cathartic operation 2nd those that act mechanically upon them 3d those that are prisoners to them. 1st Although strong & even violent purges may be used to drive out an accumulation of worms in the bowels yet they should not be often repeated as they would increase the weakness & irritability of the stomach & bowels to such a degree as to favour this increase. In general calomel will be the best cathartic inasmuch as it will tend to promote a flow of healthy bile & to restore healthy secretions. In Europe the gall of animals has been administered. One of the best forms for the administration of cathartics is that of alkoholic tincture, for the sake of the joint effect of the alcohol hence elixir proprietalis in teaspoonful doses & the tinct. “The bark of the button wood taken from the north side of the tree has been recommended. It is a nauseous bitter & a cathartic good” # “It is a question whether cowhage acts mechanically or whether it contains an acrid principle like that which exists in the nettle” # One of the remedies that I have most reliance on for ascaride in tinct [illegible]. Fill a bottle with the young inner bark fill the interstices with [prosp] spirit & give I to zfs night & morning It is an old remedy and better than tinct aloes It is tonic & deobstruent” Some of the acids to be narcotic, are more probably active merely by their pungency, odour etc. 77:b. of hickory bark or buds have been found very serviceable Podophyllum peltatum is much used but is probably not better than other cathartics. The best form would be that of a tincture 2 Mechanical remedies are not now used. Cut hair has been given cowhage though some doubt whether the operation of this is wholly mechanical. I have thought that the root of osmunda given in pieces acted mechanically The filings of tin, formerly were much employed as was also an amalgam of tin & mercury. There is a curious account in one of our journals of a man in Kentucky who took a pound of the amalgam & was unable to expel it from the bowels The mass lodged in a part of the intestines & could be felt externally It was very troublesome to him when riding. Oil has been given with the intent that it should fill the respiratory pores of the tape worms & thereby destroy its life. In Madame Nouffeurs recipe The supper of panada is intended to act mechanically by its bulk. 3d The remedies which destroy the worms seem generally to be narcotics All articles of this class however do not have this effect opium for instance. Particular animals are sensible only to particular narcotics as for instance swine are poisoned by stromonium while sheep eat it with impunity. The most valuable article of this class are the two species of spigelia s. [ma??ndica] & s. anthelmia A strange notion has existed about a little innocent [illegible] was considered as the narcotic agent Similar reasoning has been used with respect to denarcotising the opium Opium denarcotised would be not better than bread Spigelia zii in ¼ pt water to a child may be given in divided doses. It is better to give a cath. e.g. cal. or ruhb Spegelia from zfs to zf for an adult Sometimes but rarely it operates itself as a cathartic Sometimes convulsions are produced Our pink is bad because it is gathered by [illegible] packed in hogsheads & the rotten saved & the rest [illegible] The emigrants from St. [Illegible] brought what they called worm syrup which they said shd be given in the night because it affected the eyes S. [anth.] is [illegible] S. [illegible] about zi if S. anth. “Pink is given more especially for the [round worm] & sometimes for the tape worm” [illegible] [illegible] & [areca] [oleacea] zii to zfs “The French use the syrup of peach flowers & seeds They first give sulph either zi in [illegible] decoction male form & an injection of the same. They probably act by their prussic acid” 77:c. The former is the one commonly used in this country and in England It is called Carolina Pink. This is a most valuable article and is useful not only for its operation upon the worms but for its effects upon the system, in allaying the irritation which they occasion. I have prescribed it for a cough & other symptoms of irritation where I had no reason to suspect the existence of worms Then given for its effect upon the worm from half an ounce to two ounces should be given in decoction in the course of the night, accompanied with rhubarb or some other cathartic to drive the worm off while in a state of intoxication. It may be given in powder in a dose of from 10 to 20 grs The French W. Indies s. anthelmia is used & called wormgrass. It is a stronger article than ours The French use the article in form of a syrup & give a teaspoonful at a dose. Veratrum subadilla & helleborus [fetidis] belong to this class and have been given in doses of 2 to 6 grs for children In Europe the most famous article of this description has been the Felix mas Other articles of this class are camphor, prussic acid & tobacco The bark of the cabbage tree (of which there are two species vide Good) is found highly valuable in this way by the West India physicians Other articles which have been said to be successful in cases of worms owe their success apparently to their acrimony in whole or in part, such as the terebinthinate oils Oil of turpentine is the one commonly Various aromatics have been used, as chenopodium [illegible], rue tansy “The leaves of cedar juniper & [illegible] powdered 20 grs They are acrid stimulating and tonic & may have a mechanical action. It might be used to add to the powdered leaves some aromatic as rue ol. tansy [worm] wood etc.” “Melia [azidurach] bark of root or plant zfi to zi act as emetic cathartic & narcotic. Acts more effectually at the south where the recent article is used” 77:d. employed should be given in large doses, when it will prove cathartic. A concentrated solution of salt has been strongly recommended given by the mouth or by injection Ether is much used by the French & perhaps has an effect upon the worms. Some of the other antispasmodics which have been popular may also have some effect upon them such as asafoetida, petroleum the essential oil of the chenopodium etc. Perhaps arsenic poison intestinal worms I have known it cure. Ammonia may perhaps act on them 2 Of the remedies which are designed to have an effect upon the system. In severe affections from worms our first attention must often be directed toward quieting the excessive irritation of the system, by antispasmodics. Various popular remedies for worms seem to have little other virtue The chenopodium anthelminticus & c. ambrosioides called worm seed & the c. botrys. or [juris] oak ar probably valuable, mainly if not entirely a nervine. They may be given in decoction or the essential oil may be used. The garlics are used in syrup or decoction they are nervine 7 have considerable effect as condiments upon the intestinal canal. The ictodes fetidus is of this class & so are the empyreumatic oils, petroleum given in a dose of 10 to 40 drops barbadoes tar etc. For giving tone to the digestive organs and exciting their sluggish action the tonics the bitters & the aromatics are indicated while mercurial [Artemesia] ][santonica] is no better probably than the other bitter tonics Some confusion results from the appellation worm seed being applied both to this and to [illegible] botrys c. anthel. & “Indeed anything which tends to [procure] healthy secretions of the viscera. Of this kind are the mercurial which produce healthy bile which is especially [illegible] to [illegible]” # “Indian corn or maize has been supposed to favour the generation of worms in the body. The aborigines of this country have been peculiarly subject to them perhaps from this cause” Worms are far less common now as are also colic dysentery et. than formerly when cold water & cider were drunk instead of tea and coffee AT the south likewise the negroes who feed more upon crude and raw articles are more subject [illegible] of the plantations it is a rule to give a decoction of melia to the black children once in 3 months # Though you can cure worms generally by calomel yet sometimes they will resist all treatment Eupatrium perfoliatum is used for worms Flowers of [zinc] are antispasmodic so also sulph zinc Dr Rush thought well of [sugar] especially when given in the morning Petroleum seems to be a valuable article a substitute for turpentine It may be supposed dangerous, but I have used it for many years without inconvenience I began with small quantities from fear of danger, but now I give 10 30 or 60 grs It very often to produce no violent effects. Yet we must not conclude hence that it is useless. Asafoetidae for instance produces nothing but a little [illegible] in healthy persons 77:e. preparations & other deobstruents will be valuable adjuvants. The metallic tonics as the preparations of iron & of zinc, the mineral acids, myrrh, bark, the various bitters & the astringents have been found useful I have used alum whey with advantage. Among us the geraniums & all the indigenous aromatics & bitters have been given in popular practice. Alcohol from its stimulating effect upon the digestive organs will be a useful vehicle, for the exhibition of medicines. Condiments used freely with the food, will answer to the same indication The diet of patient troubled with worms should be dry & stimulating, rather than liquid & cold raw fruit, acids cold water & all indigestible articles should be avoided & in extreme cases I would advise that neither food nor drink be taken but which has not been subjected to heat. I have apparently cured patients by this means. “[illegible] toasted bread [illegible] [illegible] vegetable [illegible] though they occasion [illegible] dyspepsia” A multitude of heterogeneous articles have been used as anthelmentics, besides those already mentioned; some of them are sugar; worm-wood; rue; peach flowers; bark’ of prunus virg; valeriana selequa used by the French; muriate of barytes; injections of mur. of tin (Alibert); oxide of tin grs iii with etr. of juniper (Alibert) mur. of amm. of linseed; mur. of amm. [illegible]I with jal. or rhub 10 gr.; all the forms of ammonia; crude mercury; merc. boiled in water; aethiops mineral; artemisia [illegible] [illegible] ([illegible] [illegible]) & a. [illegible] [illegible] [s?tonica] worm seed bitter & of some value; melia azedarach much used at the south; butternut bark intensely bitter dose a tablesp. full of decoct cathartic & said to be narcotic; allows asclepiadis I think I have seen the a. [illegible] then beneficial; etc. etc. Garlics seem to do well how it is difficult to say perhaps operate upon the worms. Garlic also will relieve the eruptions of worms. It is though also that garlic prevents worms I have a very good opinion of sulph ether introduced into the rectum used by the Germans, Italians nervine & antirritant. It is valuable both in cases for worms & in those of irritation & affections of liver severe pain in bowels etc.” ½ oz or 1 oz. iron filings taste by [illegible] remedy worse than disease Wherever leaves of [illegible] are recommended you may give our common juniper For the imported [illegible] loses its strength by keeping & drying Rosenstein recommends cold water during the operation of a cathartic He recommends effervescing mixtures to destroy the worms by carb. acid An old remedy of the tonic kind is alum whey Rx milk & water equal quantities & put in [illegible] [alum] to [illegible] give the whey [illegible] children takes it pretty freely; It is a given in cases of relaxation of bowels and for ascarides & round worm It is of consequence often to have a remedy [illegible] and not require to be forced down 77:f. Various external applications have been prescribed Oxgall & venice soap aa zi made into a liniment with oil of tansy or wormwood; Aloetic plaisters; ether oz vi, bruised garlic zi, camphor zi (used by the German Brera) for a liniment; petroleum mixed with gall; Most of the patent medicines for worms [illegible] or both contain calomel, Storr’s lozenges are calomel with sugar & gum. These are his white lozenges. His brown are resin of jalap, gum tragacanth & calomel. Good on the authority of the Germans recommends [illegible] milk Electricity A popular article (cath.?) is decoction of [plantanus] occidentalis strong bitter For ascarides I rely as much as any thing upon a saturated tincture of the juglans [illegible] & [illegible] All the indigenous bitters as cherry bark [illegible] melia [azedarach] zii of recent root is divided doses ½ pt water. When dried & long kept it is apt to disappoint here. It is acrid [as the] narcotic & cathartic a powerful article The berries are also narcotic causing lard to fall down not from [choking] as has been thought The [planters] think it too powerful for [white] children! Tape worms frequently produce headache [illegible] about the umbilicus yet generally produce a sense of weight. Yet I have known persons evacuate them when they had not been suspected Case of a man who had kept taking remedies for a catarrh Finally a medicine ? brought away to his own surprise and that of his physician a tapeworm Perhaps vomiting occurs oftener from tape worm than from any other species # “When the worms are very numerous, there is a sensation of something falling from side to side on a change of posture” 78 V. Symptoms of each of the kinds of worms with the treatment. 1st taenia solum. This worm generally inhabits the upper part of the intestines & adheres so firmly as to be removed with difficulty It is sometimes solitary but commonly in considerable numbers. When brought away from the bowels many of the joints are separate & have the appearance of gourd seeds hence the name. 2 T. lata or vulgaris This likewise inhabits the upper part of the intestines and is usually in families of three or four Both are called by the common name of tapeworm They may exist without any apparent symptoms of worms or they may give rise to the severest affections In general they are attended by severer pain in the bowels & more violent symptoms in general than the other worms. The diagnostic marks of their presence in great quantities, are sense of weight in the abdomen, # irritation of the stomach nausea & vomiting loss of appetite, irregular appetite weakness of the chylopoietic viscera, bloated countenance emaciation of the body etc. All these symptoms however may arise from mere irritation of the stomach of a child Adults are more generally affected with tape worms but children sometimes have them. For the taeina solum t. lata or vulgaris or cucurbitina the gourd seed worm the spirits of turpentine has been very successful. Though not prescribed by the physicians it has been used as a popular remedy here for more than T. lata fifty years. I have known a man of intemperate habits No cautions are given about the use of the article (so far as I know) But if it does not act as a cathartic immediately, it will produce great irritation especially of the urinary organs I recollect the case of a lady who had been treated with aph turp. in N.Y. taking 2 or 3 ounces Violent vomiting & catharsis had been produced and the tone of the stomach and bowels seemed to have been permanently destroyed Worry had indeed been brough away, but then they would come away themselves & the relieve was fallacious In delicate cases it had better be combined with castor or sweet oil In the case of the lady cath seemed to do no good, they would indeed bring away large quantities but they would return in a few days. I put her upon arsenic but she left town and I have not heard from her It is difficult to tell how arsenic operates whether upon the worms or producing healthy bile For the t. lata the spts turp. seems to do better 79 take a wine glass full of spirits of turpentine to expell a tape worm Though an habitual inebriate, he said he never had been so drunk in his life & large tape worm of this kind? came away # It is said sometimes to intoxicate & sometimes to produce irritation T. solum 2d The t. lata is the most difficult of all worms to manage. Spts of turpentine do no good at least in those cases in which I have tried the article In T. solum one case I gave zfs. In another I gave it in teaspoonful doses. In the latter it operates freely as a cathartic a single teaspoonful procuring as many as ten stools Worms were evacuated but they would make their appearance again in as large quantities as before. Indeed any medicine may bring them away for the bowels are sometimes so filled with them that they come away T. solum when the patient is walking, or is asleep. I have known two quarts to be brought away in a day, & then a fresh supply in a few days after! T. solum # Arsenic has succeeded better for this kind? with me than any other remedy, which I have used. In the case of a child 5 or 6 years of age who had both the round & the gourd seed worm the common cathartics were given with some advantage, as some worms were brought away; but the symptoms still continued and the worms passed occasionally with the stools. Fowler’s solution of arsenic was administered in doses of four drops three times a day. In a few days worms ceased to be evacuated the symptoms disappeared & the child has once had no recurrence of the worms [Osmunda] cinnamonea is bitter, subastringent and perhaps deobstruent. So is polypodium vulgare and perhaps more decidedly so The polypodium vulgare & felix mas They are used in chronic affections of the stomach & bowels & thought they have not obtained much reputation for worry in this country yet they have sustained their reputation for 2000 years. It was used by Galen “The [form] is tonic” 80 I recollect case of one patient, a woman, who kept passing tapeworms, in great quantities, for months. After failing with medicines I threw them all aside & tried diet All the food taken was roasted or boiled even the water used for drink was boiled. She was cured. It must be remembered the healthy bile & gastric fluid will destroy those worms & from this fact results an important indication, which I shall presently dwell upon. Felix mas the male form has been considered in Europe, as a specific for this worm. With us the osmunda cinnamonea [illegible] ([hog brake]) has been used as a substitute for it. It is bitter, astringent & sweet. The polypodium vulgare, which is tonic & deobstruent, & other forms may probably be used also The famous fern remedy bought by the king of France of Madame [Nouffleur] is as follows. Take a super of the following panada Rx water lbi [illegible] fresh butter z 2 or 3 bread cut into small pieces zii add salt zi & boil thoroughly. If the patient is costive give an injection of water lb is in the evening olive oil zii salt gr. s. The next morning eight or nine hours after the supper the specific is to be given viz. Felix mas ziii in powder, mixed with 4 to 6 z of the distilled water of the fern or the flowers of the linden tree the whole to be swallowed at a dose. In children the dose is reduced to zi of the fern Two hours after the fern is taken the patient is to swallow the following bolus R. cal. & scamm. aa grs xii Gamboge grs V powdered fine & made into a bolus to be given at one dose to a person of vigorous constitutiokn Ether acts especially upon the nervous system on which account it has been used as an anthelmintic Alibert for taenia gives about zi in a glass of the decoction of the male form in the [illegible] an hour after his doze zi of the ol. ricini are to be given in syrup or in composition the dose to be repeated twice & sometime three times a day The worm is usually evacuated after the first doses Mr [Bonadier] directs an injection of the decoction of the male form to which zii of ether are to be added Mat. Med. art. ether 81 Mathieu adds to Mad. Nouffleur’s remedy the filings of tine & the sulphate of potash The French & German add ether to the same remedy Rothier’s method is Rx powdered savin grs xx seeds of rue 15 cab. grs x oil of tansy gtts xii syrup of peach gr. s. make a bolus Take half in the morning & half after dinner, drinking with each dose a glass of vin. tincture of peach kernels Dr Baurdier gives the following Rx sulph. ether zi decoct felix mas 1 gill taken fasting 4 or 5 an injection of the same decoction with zfs of ether an hour after zii ol ricini or zi of the syrup of peach blossom the worm is discharged half organiz Oil is used in order to kill the tape worms by filling their respiratory foramina. Ol ricini has been given for taenia & other worms in doses of 3 or 4 z Liquid carb. amm. might be given for taenia The German physicians are fond of giving 3 or 4 ounces of castor oil They are fond likewise of peach flowers Within 5 or 6 years the bark of pomegranate has been recommended. Paris says bark of the root [illegible] probable however the office preparation is meant viz rind of the fruit which is the most astringent substance to the [illegible] which we have [illegible] also cathartic! I have not [illegible] N.B. The male form is astringent, and is given to enable the bowels by the tone it gives, to bear the [strong] cathartic afterwards. Hence the union of these give in [illegible] [illegible] may be useful I have seen the worm occasionally in rain water I recollection one man of 60 who informed me he had been troubled with then nearly all his life until he removed his [illegible] Change of place may effect a cure by change of water Probably [illegible] of our cholera are troubled with this worm delicate children only suffering much children troubled with them will be faint, have turns of colic etc. you will be called [illegible] Give an injection, and no worms will come [illegible] yet give afterwards a strong cath. & or repeat the injection and worms will come away proof that they were not in the rectum They probably breed in the duodenum I have known but one case in which they were vomited up. The subsequent cath. will bring away smaller worms More is done by diet int his worm than by any thing else Alcohol in this morning especially its bitter tinctures. Condiments are useful. Worms are less common now because condiments are more used. It is said that the aborigines when they cannot get salt used potash ashes by a condiment The aborigines are said to be very subject to worms # Ascarides sometimes produce severe pain at the umbilicus and colic # “Ascarides though often found in the rectum are generated in the stomach & small intestines. Hence they are sometimes no discharged till the second or third operation Hence they are sometimes thrown up by vomiting. I have examined this point carefully 82 3d Ascaris vermicularis. This worm is always troublesome when it exists in considerable numbers though it is but seldom that they exist in healthy persons in such numbers as to give rise to morbid symptoms. They are very common in children, and not rare in adults & are called by the generic name ascarides These worms are commonly found in the rectum & hence are often said to inhabit that part This is a mistake they multiply abundantly & lodge in the rectum as they daily pass void by sphincter. Sometimes they exist in the stomach in vast numbers (hence called maw worms) so as ever to threaten suffocation by rising in a ball into the esophagus & sometimes they cause severe griping pains by their presence in the small intestines # They pass in the stools & sometimes come away spontaneously at night, they are said even to make their way to the vagina & urethra of females producing troublesome symptoms X Ascarides are most troublesome in the latter part of the day & the first of the night, when they excite an intolerable itching at night [illegible] probably than feeding They give rise to symptoms of general irritation & sometimes to a cough # Ascarides are particularly injurious to dyspeptic patients & they themselves may give rise to the symptoms of severe dyspepsia such as craving appetite, indigestion, faintings. Flatulence, cold extremities pale & sallow countenance, cough etc. The irri “They are attended with violent itching about the rectum general irritation convulsions irregular appetite pale urine flatulence want of vigorous action of chylopoietic viscera increase of mucous secretion darting pains in the abdomen stomach & chest faintness cold extremities the symptoms of dyspepsia sporadic cough” Tobacco injections & tobacco smoke injected are very useful and will often cure. It is not safe for children I have seen great prostration produced in children & I have known an adult killed by a tobacco injection # A physician who had been much troubled with ascarides told me he had tried merc. oint. externally with advantage. “I have used it but was rather disappointed # When the ascarides are in the small intestines, tobacco smoke will do not good & by its debilitating effect will favour their existence “Injections of camphor and milk have done more to remove ascarides than all other remedies I have used. The injection immediately removes the irritation produced by the ascarides & the ascarides themselves. It may be made of milk ziv to spts camph. zi This is the form in which I have used it, probably an emulsion is as good, perhaps a better form” M. M. 83 which they cause sometimes, in children brings on convulsions Whenever, finally, they exist, in the alimentary canal they are accompanied with great quantities of mucus in this part. They feed on the mucus of the intestines, the flow of which they excite by punctuating the mucus membrane Treatment It is very difficult to cure a patient troubled with ascarides. The most immediate relief is given by injection. If the worms are in great quantities & too much “Tobacco smoke is one of the most powerful means we possess for the involved in mucus, they may be completely removed by cure of these troublesome worms” injecting tobacco smoke. Injections of warm water or milk & water will relieve for the time being by washing out the rectum & if a quantity of aloes zis to ½ pt is added a still better effect may be expected though camphor being a nervine & a poison to the worms would be a still better addition. Injections of milk and water, with camphor zii tinct camph to ½ pint, will if preserved [illegible] destroy them 15 grs of [illegible] [saladilla] have been injected. Still the frequent injection, required in bad cases may debilitate the bowels & consequently invite the return of the worms. For internal administration. I have found a tincture of the buds or bark of the hickory given in doses from a tea to a tablespoonful one of the best articles both for removing the worms & for preventing their return Drastic cathartics should not be depended upon for they weaken the bowels & increase their irritability & hence favour the production of the worms. On the contrary calomel & tonics should be given to restore healthy secretion Aloes if given should not be in large doses, for that will irritate the rectum still further, but in smaller ones as a tonic Oily articles shd be avoided as butter, because they relax the [illegible] of the intestines Potatoes, vegetables All kinds of pastry avoided All the metallic tonics are useful as tonics They are thought also to be unfriendly to the worms It is said that forth ascarides a pint or a quart of sea water has been drunk with advantage, producing vomiting & purging. Salt is a good remedy. Dr Rush proscribed a teaspoonful of salt in the morning to a gentler one much troubled with ascarides. He told him after trial than the remedy would not do. Dr Rush gave him, then, for worm powders # For the worm the [illegible] the pink shd be the remedy vide [illegible] “Rhub & cal. are the best cath. but all are useful For children Rx tinct. [illegible] Fowlers solut. cold water” “Common salt ground up with cochineal to colour & disguise the article. The gentleman reported that the last prescription had answered well. Dr Rush also believed in sugar. This more doubtful The asclepiasis have been much used especially for this worm especially A. incarnata called wild hemp It is dried pounded to a fine powder mixed with molasses & given in doses of a teaspoonful Or [illegible] down and make a strong decoction [illegible] the [illegible] with it molasses and give freely until it moves the bowels This much used by the practitioners of the state more than any other article after calomel. it is an article which may always be obtained growing in clayey situation and is safe The other asclepians are similar & may be used S syriaca is the most laxative 84 To prevent the return of ascarides, condiments should be freely used such as pepper, ginger etc. in short all warming and bitter things In extreme cases let the diet be so regulated that nothing shall be received into the stomach which as not been subjected to heat. Mercurial ointment has fasted in my hands. 4. Ascaris lumbricoides the long round worm is perhaps more commonly found in the alimentary canal than any other This worm more than any other is found to have existed in the stomach or intestines while the general health has been good is the presence of worms not suspected. Strong purges may be used to remove them & alcoholic tonic tinctures given to prevent their increasing. For this latter object the carbonic acid has been recommended in the London Med. & Phys. Journ. & in confirmation of the idea I have used soda water with advantage Melia azedorach or pride of India a decoction of the bark is much depended on at the south for their young negroes who are much subject to worms. It loses much of its virtue when dried. The spigelia is also sued but of this I shall speak under the head of general treatment. I recollect with an aff. of the liver wh often vomited up dark [gravous] blood, which had evidently been long in collecting. Finally he was said to have thrown at a snake. Many eyewitness testified to the snake & to its eyes & teeth. I saw it. It was a very large round worm of the kind To be distinguished only by the violence of the symptoms. The same itching at the arms will exist as of the ascarides, but non violent etc. “Treatment similar to that for ascarides. It is more common than is generally supposed. Many of disease & death by irritation from an unknown cause, are probably owing to this worm. In examination the contents of the bowels should be placed upon linen cloth and then this worm can be seen.” For the gordius Linnaeus recommended the angelica Archangelica (not our viz the [atropur????]) 85 5. The tricocephalus is but seldom met with The irritation produced it may be so great as even to bring on delirium & will be manifested by screaming throwing of the hands & [fat] etc. I have found this worm in a fold of the volvulus of the intestines vide Volvulus. I should try narcotics for this worm, but cannot speak from my own experience. I should recommend also an injection of a table spoonful of ether in a gill of water or mucilage. Ether given in this way will undoubtedly pass the valves of the intestines in a state of vapour Vesicular worms, according to the old division of verminous diseases, are met with commonly in the brains of adults & are attended with the symptoms of vertigo, convulsions apoplexy & hydrocephalus. Cases of worms & of colic are much less frequent with us than formerly; owing to the change in our mode o f living. They are said to be very common among the aborigines of this country One volvulus may be received within another a second, a third and fourth time & [illegible]. The whole may then become inflamed, the vessels may run from one to another, and the whole become one complete mass of organised matter or sometimes [illegible] “It may occur in any part of the intestines except the rectum though the colon is often received into the rectum” The symptoms of the two kinds [illegible] [illegible] owing to the different susceptibility of these two portions of the al. canal, and the diff. ages of the subjects of each Nor located in books vide Ed. med. & surg. J where the best account of it is given. Good merely mentions it as an accident that is found sometimes to have occurred in ileac passion “Predisposing of exciting causes” The cavity of the natural stricture may not be large than a goose quill, & such children will be very liable to an occurrence of volvulus This is not a primary disease. It occurs more in some families of [illegible] fibre & [illegible] phlegmatic temperament It may occur from debility of constitutional or that of the bowels [illegible] by bowel complaints etc. Local violence One instance, in here the child was apparently thrown into it by being carried over the shoulders 86 Volvulus or Introsusception This is a disease with which I was at first very much perplexed especially as I derived little satisfaction from the books Volvulus or introsusception is the reception of one portion of intestine within another. It doubtless exists often in a slight degree, when there is a strong action of the bowels & are inverted peristaltic motion & the bowels disengage themselves. Sometimes there is a double involution, or one involution within another. In some cases likewise the cavity of that portion of the intestine is entirely obliterated by the tumefaction of the coats. I have always found in post mortem examinations, that the upper portion of intestine was received into the lower & not vice versa the involution having been caused apparently by inverted peristaltic action This affection of the intestines occurs oftenest in children though adults are liable to it. It would seem also that some families of a leucophlegmatic temperament & delicate constitution are particularly liable. It may be caused by a natural stricture of a portion of the intestinal tube when it will be incurable It may arise from extreme irritability; local violence & injury may occasion it, & the irritation of worms may bring it on. Drastic cathartics may bring on volvulus & hence should be cautiously avoided where there is a liability to it. Bowel complaints, as colic, cholera, dysentery etc. sometimes terminate in one or more volvuli of the small intestines. The disease is more frequent in the summer, when debility is greater & bowel complaints prevail “Symptoms incessant irritation one or two copious evacuations but usually these have ceased entirely before the physician arrives constant efforts to vomit, resembling hicup constant efforts to pass stools & nothing passes but mucus streaked with blood Generally mistaken for hydrocephalus In bowels complaint of delicate children look out for volvulus It is much more common in some seasons than in others. About 10 years ago they were quite common. I had many letters from our students, who met with the disease & disagreed with the phys & gained [reputation]. They frequently sent me such accounts. Sometimes there will be a partial involution of the large intestines [illegible] to relaxation of inner membrane what descends like a funnel & may be felt by the finger # In the large intestines there is not very much irritation than is torpor of al. can. not much vomiting except upon the administration. There is no purging You may sometimes determine that of the large intestine by heaving the peristaltic action discard & stop at the [illegible] This is most common in adults. The symptoms are more mile # It occurs in females who have had long continued effetion of uterus, occurring in females about cessation of [catamen] and from long continued bowel complaints. The [inner] membrane will descend like a funnel An injection will perhaps 87 Symptoms These will be different according as the affection is of the small or of the large intestines 1st Where the small intestines have one or more volvuli the symptoms [illegible] vomiting or Symptoms like those of violent injury to abdomen vide case 1st 6.89 a constant endeavour to vomit as often as once in ten or fifteen minutes the matter thrown up being a greenish fluid or simply mucus. In severe cases the vomiting is attended with a discharge from the rectum at the same time. The stools are fecal at first & copious but afterward they are small in quantity & consist principally of white mucus streaked with blood the blood not being diffused throughout the mucus as “no fecal smell generally” in dysentery, but in streaks or specks. These symptoms are attended by others which indicate great inquietude or irritation such as throwing the h ands & feet, rolling the head paleness of coutenance This set of symptoms resemble those of hydrocephalus & hence volvulus is often mistaken for this disease. The pulse is small and frequent “[illegible] usually occurs in 24 or 36 hours” 2 A volvulus of the colon or rectum is not usually attended with much vomiting unless this is excited by cathartics. It is attended with the ordinary symptom of constipation. There is no evacuation from the bowels unless at times a little blood and mucus. If the passage be not completely closed, an enema thrown-up will remain & not come away if completely closed. it either cannot be thrown up or it returns immediately. Blood often follows the introduction of the pipe. Indeed the inflamed part is often so low as to be reached by the pipe & admit of being felt by the finger. come away immediately. [Schyl?la] of feces may come away And large quantities of mucus may come away sometimes ½ a pint. This is not apt to be fatal. Treat by a strong inject prescribe for the [illegible] with conium [illegible] etc. mechanical means The more cath. you give the more the unsolution is increased therefore give more Give mucilaginous injection, in involution of the small intestines, sufficient to fill the intestines. If it is said that the injection will not pass the valves. I answer that whether by sympathy or in whatever manner, I am satisfied of its utility # Give [illegible] enough to allay irritation I have treated # patients for 8 or 10 days without evacuation & cured them Not long since I had a case in what I suppose there was such a volvulus, for the attendants could not make the child receive injection. “thought the bowels were swelled” The child was suffered to get 8 or 10 days without evacuation & eventually died of another disease with which this was connected # In the incipient stages, filling the intestines with warm water [illegible] recovered. I was led to it from its [illegible] strang. hernia I am satisfied it acts well as a local nervine etc. I would recommend the injection of ether in cold water table sp. to a gill warm wat. will make it fly off. The inject of it is practised by the French & Germans. Other antispas. might be [injec??] is asaf. petroleum etc. 88 We may often hear a rumbling noise proceed as far as the stricture & then stop. Treatment The indications of cure are principally, to relieve the excessive irritation both constitutional & local & to attempt the restoration of the involved intestine chiefly by mechanical means When the small intestines are affected we must give opium and aromatics & depend mainly upon these as internal remedies, until the intestine restores itself. As an adjuvant the warm-bath will be valuable & fomentations or irritants, as mustard & horse radish leaves may be applied to the abdomen. Soothing injections also may be copiously given. The quantity of opium which will be safe at a dose may vary from half a drop to 30 None but the mildest cathartics are safe, as blue pill and aromatic tincture of rhubarb I have succeeded in giving only a decoction of senna & the blue pill [Savage] When volvulus is in the large intestines all our remedies must be given by injection. The warm bath etc. may be used & we may also attempt the restoration mechanically, by means of copious injection repeatedly given & thrown up with force Two cases are related of young men cured by inserting into the rectum & keeping these for a considerable time as spermacete candle with a quantity of opium at its extremity. The first case which I had I treated for constipation with repeated cathartics, which are thrown up etc. The attendants complained that they could not give the injections when I ordered I was ignorant of this case Tried warm bath & every remedy for colic constipation etc. Upon examination at first the colon was apparently wasting at the sigmoid flexure where there was a large tumour which we thought to be a malformation It proved to be a repeated & insolution of the intestines Inflammation had taken place & the whole was adherent, some [illegible] Afterwards I was called too late, to a similar case which upon an examination showed circular appearance Afterwards called in consultation to a child said to have hydrocephalus all the children of which family had died in a strange way. I pronounced the disease not hydroc. but some could not say what was the matter. No treatment was serviceable. Examin showed volv. of small intest. Symptom is above. vide p. 204 The children of the family were subject to diarrhoea & were leucophlegmatic. I afterwards [illegible] the family and was very cautious about cath. giving nothing stronger than blue pill or tinct. rhub. The family raised 5 or 6 children afterwards Case of a student [unaccountable] Dr Munson & Dr Smith at a loss. [Cath.] retained & yet not thrown off by vomiting Sitting by him I observed a rumbling noise Which he said upon my enquiry, he felt & which stopped. I felt the stricture. Spermacite candle, sharpened, opium at [end]. kept up about a [illegible] [renewed] afterwards injection passed up Case of a gentleman on the wharf similar cured 89 Cases. A man over whom a cart had passed without leaving any external injury, died with all the symptoms of volvulus of the small intestines. On dissection the duodenum was found cut entirely in two. One remarkable physiological fact occurred in this case; a cathartic was given by the mouth & produced a regular evacuation from the anus, although the intestine was completely severed. An interesting case occurred to me in which the worm ascaris tricocephalus was found to be the cause The worm lay in this fold of the intestine. Grace Linsey, a delict schoolgirl on was taken with slight in disposition for 3 or 4 days the rejected her food by vomiting then came on constipation with vomiting attended with great restlessness & throwing off the bed clothes, cold extremities, low & small pulse the tongue not much furred, little or no thirst, no tumefaction of the abdomen no determination to the head. She was visited on Tuesday and died on Saturday. A blue pill was given & followed by 15 or 20 grs. of calomel in divided doses No effect was produced though they were not rejected. Opium and stimulant were tried but were not retained. There is no pain but faintness & an uneasiness about the alvine & urinary passages. Both copious and small injection pass up well but produce no evacuation. On Wednesday injections produce stools which are clay coloured. Black vomit came on two days before death. P.m ex. liver very pale little bile in the gall bladder no marks of inflammation cavity containing the intestines very dry as in cholera. Two volvuli were found one in the ileum which was disengaged with difficulty, & one in the jejunum In other cases with similar symptoms I have had supposed there was volv. caused by worms, but have had no opportunity to examine Vide p. 204 [illegible] Lindsay’s case continued. After the examination we accidentally observed some of these worms minute & coiled up among the mucus on the cloths. The worms seem more calculated to irritate the bowel than any other “If it could have been known that the worm was there, perhaps tobacco should aught have succeeded # It is called leg ache in slight affections alluded to by DR Rush Affects the legs, calves of the legs [illegible] continues extends up to the [illegible] coats” It is a disease manageable in its commencement Being a severe disease it calls for decisive remedies The indications are to allay pain equalize excitement & promote peristaltic action by opium by diaphoretics by cath. Cal. in full doses some would call 5 grs a full dose some 10 But if 5 gr. should be given every hour it would amount to a full dose. You may give 10 gr. 2 or 3 times repeated. AT the same time apply warm bath & fomentations not regarding your giving cath. Put drafts at the feet. Follow the cal. with senna, salts etc. But do not be too anxious about the calomel’s operating immediately It is better that it shd lie sometimes in [illegible] vessels With the cal give opium also guiacum & guaicum with dovers powder the latter to act on the skin and the whole to produce a decided [nerve] action affect on the al. can. and on the whole system 89:a. Nervous Rheumatism Infantile neuralgia This is a disease which has never to my knowledge been described in the books, though it may have existed unnoticed I first met with it some years ago, but it is [not] some years since I have seen of a case. It may occur again It occurs in the winter and spring mouths & occurs after exposure to cold especially after the feet have been in snow water. Children are the only persons that I have known attacked # This disease is in its symptoms allied to neuralgia acuta. The affection leg ache is probably allied The attack is sudden after exposure to cold with excruciating pain in the inferior extremities sometimes rigidity of the whole muscular system more or less disorder of the digestive passages (apparently the muscular coat of the intestines is affected) abdomen frequently tense and full stomach sometimes irritable. If the disease advances there is nausea, vomiting, tumefaction of abdomen (appearance of tetanus?_ (coma?) etc. and the patient dies in 4 or 5 days The indications of treatment are to equalize excitement by acting upon the whole surface of the alimentary canal and skin at the same time introduce new action in the system commence with a full dose of calomel 5 to 10 grs or 20 & follow it by senna and manna, or castor oil and enemata “I do not expect that cal. [illegible] I as above will operate at 8 years therefore follow it. Immediately after administering the calomel I put the patient into the warm bath or the feet in to the tepid bath, wrapping them afterwards in flannel or boil cedar boughs in water, roll them in cloths and apply them to the body & feet. Irritants also may be applied to the extremities and to the abdomen Sometimes it will be best to repeat the cal in the course of 2 hours. The stools will be fetid and dark but this must not be considered as an indication for further evacuations as the appearance may be caused by the calomel, and is a sign that secretion is beginning to take place. After producing free evacuations by your cathartic you must keep up a regular course of exciting the secretion by cal. & guaicum with Dover’s powders, especially if pain continues & keep up a diaphoretic action by Dover’s powders calomel and camphor alternately increasing doses if necessary. Calomel and gum arabic, as an emulcent, & calomel and decoction of cedar twigs, as a diaphoretic may be given Give the calomel first in divided doses If cold applications are made to the extremities, to discuss the inflammation the disease is translated to the stomach and death is the consequence I called in the first stages, & am always successful in effecting a speedy cure The irritation of the system is so great that secretion is prevented hence the production of secretion I have been called to patients with [illegible] where little had been done the abdomen was swollen the patient went into a comatose state & died and that too where the disease was not of the most violent form After the bowels are thoroughly evacuated depend upon diaphoretics camphor guaiacum and [illegible] etc. giving so as not to offend the stomach and beginning gradually It is a violent and excessively painful disease and it is a great satisfaction to the phys. to cure it Dark stools [illegible], satisfied “The pain usually begins in the calf of the leg and extends to the contiguous parts. Sometimes it is attended with tetanic spasms & a constant rigidity of the abdominal muscles. The stomach becomes in these cases irritable, and nausea & vomiting prevail. In the progress of the disease the abdomen becomes full and tense, with constipation.” “It should be our leading object to make the muc. men. of al. can. & the cutaneous system active [concert] After the operation of cathartics, if the pain is severe give diaphoretics with opium, as Dover’s powders. Camphor & cal. in small doses as an alterative. If the stools are watery & fetid give opium ¼ gr. guaiacum 1 or 2 grs. camph. 1 gr. Ipecac ½ gr. with cal. repeated till some effect is produced not to salivate, but to this children are not so liable as adults” Young physicians are often called in a case of convulsions as their first case The neighbors & friends (women) have assembled in great numbers and their sympathies are excited. Hence an impression is made with respect to a young physician’s talents which will be of great service or detriment Morbid condition to brain so that ordinary stimuli produce convulsive action Convulsion fits may continue 5 m or from 1 to 2 hrs 90 Convulsions vide costiveness 12:a This is a very common disease of infants. The mortality from it is truly appalling nearly one seventh part of the whole number or deaths of patients under the age of puberty by the bills of mort. in Phil in 20 years Medical writers commonly make two kinds of convulsions idiopathic and symptomatic, the former arising from some morbid condition of the brain and nerves and the latter from some other disease, or from irritation. Children are subject to both kinds & most of the diseases of children may be expected when they prove mortal to terminate in convulsions The causes of symptomatic convulsions are as various as the agent capable of producing irritation though the causes of convulsions in one child will not necessarily produce them in another. The susceptibility to them varies with the age of the child and the peculiarity and degree of delicacy of the constitution. Convulsions may arise from the sudden suppression of evacuations to which the system has become habituated. Irritation from teething is a very common cause. Worms in the alimentary canal may excite convulsions. But perhaps the most frequent cause is the presence of indigestible substances in the primae viae. irritating the nerves of the stomach & through them those of the whole system. Over distention of the stomach, even with food of a healthy quality interrupt the progress of digestion & the food undergoing action [illegible] fermentation “Or the excessive quantity of food may produce convulsions from the mere stimulus of distention” “Dyspepsia is a cause” This is an important maxim in the first children of young mothers Their anxiety of mind will often affect their milk 91 in the stomach, becomes noxious matter & excites convulsions In the season of fruit we may always suspect this as a cause in children old enough to eat it. Calomel has been known to be so irritating to the system as to bring on convulsions Costiveness also is a cause of convulsions in children A change in the quality of the milk of the mother or nurse, produced by improper food or by strong affections of the mind, in some instances is the cause of convulsions in young children. Hence not only the diet of nurses should be regulated, but their minds kept tranquil. It may be observed also that the countenance of the mother or nurse as also those of the bystanders has more influence upon children than is commonly supposed. Even a child but 3 weeks old, will be strongly affected. In some families there is said to be an hereditary predisposition to convulsion among the children. For the treatment we have two indications 1st to remove the exciting cause where this is local & 2nd to relieve the irritation of the system 1st We must enquire into the causes with with care. If evacuations are found to have suddenly ceased they must be restored. The guns should be lanced. Anthelmintics should be given if there are worms If improper food is suspected we must be particular in our enquiries, or we may be misled by a [vague] & general answer. When the convulsions have been brought on by improper food or by food in large quantities recently taken the stomach should be evacuated by an emetic of 5 or 6 grs 4 to 8 of sulph of zinc or of ipecac. # How long should we wait after giving one cathartic before we try another? the child being in convulsions all the while? The equilization of temperature will do a great deal to remove convulsive action Besides the soothing of the [nerves] etrc. Some rely on one and [illegible] or another Oil of a amber is not in my opinion better than many others The oil of amber apparently is the [illegible] the oil of [capal] brought from its E. [illegible] It is recommended to dissolve the oxyg oil in [illegible] [but] it is slow of solution It dissolves readily in either 92 If the offending substances have probably passed the stomach & the irritation is in the bowels, these must be evacuated as speedily as possible giving and injection to begin with [illegible] it to [illegible] cathartic. Sometime it will perhaps be best to give a dose of calomel large enough as to operate both as an emetic & cathartic. Frequently large & repeated doses of cathartics will be needed in order to overcome the torpor produced by an excessive quantity of food. The food also diminishes the cathartic operation is the case with the French [dinner] pill. We may give calomel, 5 to 10 grs. or scammony 3 to 4 gr. jalap 2 to 3 gr. senna & manna, castor oil, neutral salts etc. If dry cathartics fail to produce the desired effect, the liquid should be tried. Sometimes will be acted on by one kind when they will not by the other # If one fails after 3 doses try another & assist with injections Begin with cal. & follow with the others 2. If the convulsions continue after the removal of the cause we must rely upon antispasmodics or even at the commencement. Of these the warm bath must be considered the most powerful remedy in convulsions of children always [illegible] & often efficacious. Its influence is immediate and extensive. Antispasmodics, as pearl ashes or aromatic herbs, may be put in to the water of the bath Of antispasmodic articles a great variety are used. Oil of amber Dr Rush called his sheet anchor in spasmodic diseases. It is useful internally, and applied as an external irritant along the spine. The artificial musk a preparation of amber is in my opinion a better article than amber itself, for all cases where amber is “# Seneca oil is more limpid & pure & approaches nearer to naphtha” Soot is a [illegible] Soot is efficient as a nervine tonic & deobstruent It is sometimes very efficacious in jaundice & dyspepsia It was very popular in Philadelphia with ashes for stomach complaints “The British oil is manufactured in this country from Barbadoes ter & spts turpentine” The nostrils may be rubbed & it may be given internally “also rubbed on the skin” Though so offensive to the small yet children taking the tinct readily potash [illegible] & [illegible] All the alkalies & alkaline earths are antispasmodic. They are not nervine properly. There yet seems to be abundant testimony to their antispasmodic properties. They are to a certain degree tonics. i.e. they have a specific action on the mucus membranes. I have maintained [illegible] they operated by generating excitability a view supported by Jobe vide Hufeland’s Journal in Lond. Med. & Phys. 93 indicated. The mineral oils from whatever source obtained, such as petroleum, seneca oil, British oil, are little inferior to the oil of amber I prefer the seneca oil 5 to 30 drops #. The eympreumatic oils are useful antispasmodic and soot is often given by nurses in decoction Ammoniae in any form is a good antispasmodic A solution of ammonia in spirits often contains an empyreumatic oil of this solution we may give to a child from 2 to 6 drops in an ounce of water. Either the spirt, the carbonate or the aqua ammoniae will be useful in alleviating spasms in children either applied to the nostrils, rubbed upon the skin or given internally. Dippel’s animal oil, a very fetid substance distilled from bones in a state of putrefaction owes to antispasmodic virtue to the presence of ammonia. It is too disgusting Castor and valerian are good articles of this class, but in cases of children they are too bulky & a sufficient quantity cannot be introduced into the stomach. A more powerful article than these is the asafoetida fetid gum 10 or 20 40 drops of the tincture. This is a very valuable remedy to give by injection using for this purpose either the tincture zii or a decoction all the alkalies are antispasmodic & are proper for children. The most powerful is pearlash given by injection, zi to zii in lbis of water I have seen more sudden and permanent effects in cases of spasm produced by injection of this kind, than by any other remedy. It has been successful in cases both of In for [illegible] who have [resumed] in convulsion 2 or 3 days when a variety of narcotics had been given. I have seen surprising effects produced by the injection These applications sometimes fail & we cannot tell to what sort of cases they are Yet we must have a variety of resources if we would be able practitioners Opium is powerful, but though it frequently relieves, yet it sometimes aggravates the symptoms I have given it with great success in paroxysmal convulsions anticipating the paroxysms yet in these it will sometimes fail 94 infants and of adults. Sometimes however this remedy fails & I am not able to point out in what particular “We are compelled sometime to practice [illegible]” instances it is indicated. All the narcotics are antispasmodic. Opium is a powerful antispasmodic and may be given to patients of any age when the condition of the system does not contraindicate it vid. lect on m. m I have given opium where the convulsions were violent & returned at stated periods with fever preceding. When the convulsions appear at regular intervals, as once in an hour, or day, opium in repeated doses may be considered a specific. Counter irritation may be valuable adjuvant in the treatment of convulsions. Oil of [origanum] & similar articles may be rubbed along the spine drafts may be applied to the feet and wrists & mustard horse radish leaves etc. to the abdomen. When the convulsions are frequently repeated in children and become in any degree periodical, a cathartic of calomel given once or twice a week, rarely fails to prevent their recurrence. If this fails I give stramonium or other narcotics If convulsions arise from organic affections we can expect to effect more than to palliate instead of curing the disease. “Counterirritation by mustard, horseradish etc. may be useful” An injection can do no harm can always be administered and if one cannot administer articles by the mouth Irritants may be applied immediately e.g. mustard horseradish garlic N.B. we do not need powerful vesication for the tender skin of infants. Even garlic sometimes vesicates Ammoniae to nostrils & in mouth Be sure that you have [water] enough to [illegible] the child completely for the nerves are apt to think that it is sufficient to half [illegible] child & then sprinkle or scatter water over producing an equal excitement Friction may be applied while in the bath & after coming out [illegible] with dry flannel If the irritants have been applied before the bath taken then off when [illegible] about to immerse in the bath & put them on again if necessary after coming out If the child seems to be in a state of asphyxia the emetic may not take effect; then irritate the fauces the child being lard on its abdomen supported by the hand of the nurse 95 When you are called to a child in convulsions, without previous sickness, direct an injection to be immediately administered and the warm bath to be prepared. if the injection does not relieve, put the child in the warm bath previously adding pearl ash in proportion of zfs to a gall. of water. Let the child remain from 5 to 15 minutes taking it out when it begins to grow exhausted. When taken out of the bath let it be wrapped in flannel & put into a warm bed. Then apply irritants as mustard, horseradish garlic, or aqua ammonia to the abdomen feet and wrists Apply aqua ammonia to the nostrils and temples As soon as the child can swallow give a dose of calomel; If the countenance is pale or livid the cause may be suspected to be some offending matter in the stomach & an emetic ipecac not [illegible] generally should be given. We may often succeed in exciting vomiting by irritating the throat with the finger or a feather & this method should be tried when the patient cannot swallow & is known to have taken improper food or when it is desirable to hasten the operation of an emetic. The child will vomit with much more ease if it is held lying with its belly upon the nurses’ hand, which this supports the abdominal muscles If the child is much agitated at the sight of the water which it is to be immersed, let the tub be covered with a blanket & the patient gradually lowered into the water there will then be no difficulty 96 Epileptic fits are very frequent among children Epilepsy is defined by Good A “spasmodic agitation & distortion, chiefly of the muscles of the face; without sensation or consciousness; recurring at periods more or less regular.” One side is generally more affected than the opposite The limbs may be fixed and rigid with twitching of particular parts. The pupils may be contracted or dilated & the attack may be followed by coma. The attack may be abrupt and without warming or may be preceded by hilarity, or a giddiness or other unpleasant sensation. Sometimes there is what is called the Aura epileptica, a sort of formication, creeping up the body for which the ligature may be applied The fits may be kept up by the constant presence of the cause such as malformation of the brain etc. or, by habit & while in the former case the disease will be incurable, in the latter habit will be very difficult to break up. The causes of epilepsy may be, malformation of the brain tumours of the brain derangement of the system produced before birth by syphilis & rickets or the same causes as those which produce the rickets & in children oftener than after preventing the disease may also arise though more rarely from mere excessive irritability of the system, even’ without any exciting cause of irritation such as indigestible substances in the alimentary canal or suppressed evacuations Among children however epileptic fits are most commonly excited by teething, suppressed evacuations & the irritation of a morbid condition of the bowels or of In scrophulous children remedies for scrofula may be given. [illegible] rickets I have often found advantage from blisters behind the [ears] I have found the cath mode of treat successful for children within the year especially calomel In some cases the most powerful cathartics are required If there is acidity of the passages so that cal. seems to gripe much [illegible] chalk any quantity from 5 to 10 It is immaterial whether the action is chem. or certainly the effect is good The system being very irritable ordinary stimuli or rather a little more than ordinary brings on [illegible] Hence improper articles improper exertions of mind & body etc. Careful management & [illegible] 97 indigestible substances in them. The treatment of epilepsy must vary with the causes which produce it but does not differ materially in the case of children from that of convulsion fits In epilepsy from rickets I have used the cold bath with advantage. In children our attention in the treatment of epilepsy must more especially be directed to the alimentary canal. Cathartics are far more valuable with them than for adults. I have almost always succeeded by means of a course of mild cathartics & joined with one of tonics, such as the tonic solution & the different preparation of iron When called to an attack brought on by offending matter in the stomach and bowels, we should commence the treatment with a strong cathartic in order to thoroughly clear the alimentary canal calomel is the best article but if the bowels are loaded with mucus so that calomel fails to operate we may conjoin 1 or 2 gr. of gamboge & of scammony & 5 of jalap & this though powerful, will yet operate kindly. In the subsequent treatment calomel should be given 3 or 4 times a week; though if there is a deficiency of mucus in the bowels an abrasion as it were the blue pill will be preferable or chalk may be conjoined. Among infants most cases are curable by careful management, both of the physician of nurse The diet should be regulated with great care Generally however there is a morbid appetite, & a sub-[insanity] There is often a difficult, particular waywardness [illegible] like into [illegible] etc. In children more than a year old I have given stramonium so far as to dilate the pupils keeping the child under the operation of it I have not prescribed it to children under 2 yrs or 18 m. I recollect one case in which the convulsion begun to subside as soon as the pupils began to dilate I would not prescribe to [illegible] but to [all] symptoms e.g. tonics all the nat. ton. tinc irr. cap. lead I would give the lead where cathartics, from the excessive irritability of the al. can. aggravate all the symptoms Lead will produce a torpor or sub paresis contrary to this Narcotics also will meet this condition Opium will occasionally, but not generally Why it is we know not but the fact is that phys. do not depend on [illegible] ep. seems to cause a determination to the head 98 with regard to food. This subderangement of the mind manifests itself also in other ways by oddity of appearance gesture & action. A strange propensity for climbing for instance is met with & epileptic children will often be so active & so artful as to be very difficult to manage For more particular treatment see my lecture on m. medical articles stramonium & nit. silver [illegible] turpentine from 10 gtts to zi diluted stramonium, camphor, opium atropa belladonna & most of the more powerful narcotics Arsenic zinc is one of the best of the metallic tonics Actual cautery, [moxa] etc. have been highly extolled “In epilepsy caused by rickets or by the same causes as those which produce ricketts. I have used the cold bath with advantage” “Mercurials followed by mild cathartics [Seontod??] etc.” The child will be still breathing languidly The parents think it dead If you look at it carefully you will perceive as languid treating & looking at the eyes you will often perceive a little convulsive motions of the balls pulse not much disturbed The child continues a few [illegible] with paroxysm & comes out with a scream like an adult from nightmare Not dangerous In a few instances [somerset] Case adult patient [illegible] a chair stands fixed eyes fixed come out with a stare irritable & sub derangement for a few days Afterwards [somersets] “asleep once a sleep twice” Case a girl last year gather up [illegible] [somerset], even 50 times than cataleptic then exhausted This case changed from chorea to catalepsy Repeated bleedings did not change the emaciation etc. 99 Catalepsy This affection when it affects children, is called in poular language still convulsions. It is a very rare disease among adults, but among children I have met with several cases of it In catalepsy the muscles are universally or partially affected with a tonic spasm. The patient remains fixed in the position in which it happened to be when seized appears asleep, is insensible and scarcely breathes. The eyes are commonly fixed, but sometimes have a little motion. The paroxysm may terminate with common convulsions. The length of the paroxysms I have known vary from a few minutes to three hours & in some cases they are frequently repeated The disease arises from the same causes in general & requires the same treatment as epilepsy & convulsions. Cataleptic convulsions sometimes follow other convulsions & in some instances have been brought on by drastic cathartics In adults catalepsy is often followed by irritability & a degree of mental derangement. “Catalepsy arises from the same causes and requires the same treatment as epilepsy chiefly by cath. & antispasm. Sometimes children are affected with catalepsy without it being observed When I commenced practice I thought the notion of still convulsions a mere whim” Dancing before the [illegible] of St. Vitus Dance [illegible] 3 or 4 well persons Comes on gradually parents complain that their children are getting into bad habits Awkward motions The dis. is not benefit. by [illegible] I recollect a gentlem. 40 or 50 yrs told me he had chorea when a child & recollects perfectly the indignation, horror & disgust when so long as to be unable to speak [illegible] Hand carried not to the mouth Sometimes the motions finally become regular “The dancing master” feet blind [illegible] then hands then body then stop like a statue then begin one foot like a [falling] [illegible] 100 Chorea Sancti Viti This is a disease not to be mistaken in its ordinary appearance the voluntary muscles are but partially subject to the well and their motion is convulsive. It occurs oftenest in females of relaxed habit & about the age of puberty especially if they have grown rapidly or been much confined to the needle or to study. In children this disease is often caused by irritation in the primae viae Chorea also arises in some cases from a peculiar irritability of the system in which ordinary stimuli produce convulsive action This irritability may be accompanied with relaxation, or with increased action together with a determination to the head. Indeed it is said sometimes to be connected with inflammation of the brain & hydrocephalus. With those who are predisposed to this disease, particularly if they are females about the age of puberty affections of the mind may bring it or epilepsy sometimes runs into chorea, or alternates with it. Finally, the disease may come on in a very gradual manner, so as not to be suspected, causing a strangeness in the gestures walk etc. which at first is attributed by the friends to the formation of bad habits. This disease is rarely fatal and is not difficult to cure in patients under the age of puberty after that period it is seldom cured. When the disease is of long continuance a great variety of remedies are generally “When I give cathartics in chorea it is not for the evacuation but to produce a new action. All cath. will not act favorably. Hamilton’s views in prescribing cath. are not generally correct.” There sometimes irritation of al. can. from accumulation of feces about the coecum. Hence Hamilton’s plan of purgatives Purgatives will cure but [general] by impression on system It is said to arise from a tonic infl. of brain I have read periodicals have not so I have seen all kinds of treatment tonics, cath narcot. electric. galvan. cold bath etc. etc. Perhaps no disease prescribed for more [illegible] periodically We find one and another article fails and are obliged to go the whole [illegible] off [illegible] narcotic etc. # “In one case of chorea I tried the arnica until the head became affected. The patient began with a decoction of zii the flowers & increased to zfs without any abatement of the disease” Prof T’s [illegible] [illegible] Nux vomica has been used with success in many cases but there are other narcotics which act more powerfully & more certainly I have not used it deterred by [Ba??] [Surrey] who found it injurious for some convulsive cases “Stramonium succeeded in a case following epilepsy” 101 tried and the one last given is apt to be considered as having effected the cure; but I am inclined to think that in many of these cases the disease instead of being cut short by the treatment and run its course and then ceased of itself The most common indications are [for] narcotics and tonics with antispasmodics as palliatives & permanent counterirritation along the spine in some cases. In children however cathartics are commonly indicated; though in general the plan of treating chorea by cathartics, has not succeeded very well in my practice. Dr Hamilton however depended upon cathartics and had better success, though it may be remarked that those who act on that treatment are also the metallic [illegible] When there are symptoms are symptoms of worms, of hydrocephalus, or of inflammation, of the brain or when the disease follows epilepsy we must treat as for those diseases; & if it the chorea is the result exclusively of the peculiar irritability above alluded to, narcotics must be our chief dependance. The principal articles which I have employed in my practice are conium, conium & iron sulphate of zinc, sulphate of iron & other metallic tonics. Various narcotics are used, as the nux vomica in doses of 1 or 2 grs of the seed in pill or 15 or 20 drops of the alcoholic tincture; and antispasmodics as valerian musk etc. may be used as palliatives Cullen’s favorite tonic was the ammoniuret of copper 1 to 4 gr. I have lately used it with advantage in pill 2-3 hours in creasing other tonics are mineral acids, nitrate of silver, bark & the arnica montana #, which is a narcotic & tonic & was successfully used by Dr [Monsen] in chorea” Dr. T’s copy [M. ?] “Sulph zinc 1 gr. may be given 3 or 4 times a day nit. sil. 1/6 to ¼ gr. succeeds best in relaxation of the blood-vessels” “Evacuate the first passages and restore the healthy secretions & irritability of the system by tonics & antispasmodic “I have rarely effected a cure by cathartics though I generally begin with them The cure with antisp. & tonic is slow 2-3 [illegible] with narcotics more speedy but uncertain” A good deal may depend upon the careful management of the patient keeping him quiet & amusing him especially avoiding the irritation of the [pressure] and the impertinent curiosity of strangers The young man in a debilitated “So camphor has sometimes been given in mania to such an extend as to produce epilepsy & sub-apoplexy & this sometimes cures the mania” 103 double the quantity, when the head began to be affected still there was no considerable relief The patient was finally cured by taking the bark in substance zi a day. One case which came on in the gradual manner above described & was brought to a high degree by a dysentery proceeded so far at least as to present the peculiar symptoms of hydrophobia such as horror of water etc. convulsives perfectly [like] that frothing of the mouth etc. died in coma exhausted narcotics tonics etc. no effect excitability exhausted by [illegible] This disease may affect the mind causing it to run upon particular subjects especially upon that of numbers & calculation. I once travelled a short time with a book pedlar who had the odd gestures of chorea & had also this facility in calculation, being in this respect fully equal to the famous [Serah] [Colbourn] [Serah] [Colbourn] though furnished in Europe with the best advantages for education never improved and this result I ventured to predict, when I first heard that he was to be educated. I have seen several such cases. # They have a peculiar articulation & expression of countenance; and are deficient in memory and judgment. Vide [illegible] 12 [illegible] for [Serah] [Colbourn] Case girl at stool good talents studied hard [stand] out of schools [illegible] Cal. narc. cath. tonics operated but [Elateri.] 1/16 gr. once 4 hr in about 24 hours deadly sick nausea prostration vom. purg. disease broken up. It may be diff. to class this A year after similar causes brought on a second attack # Connected with acidity gives great pain not dangerous “This is a troublesome and not unfrequent complaint, arising often from improper food and that stab of the stomach which causes acidity. In a torpid state of the stomach when the healthy action ceases or is feeble, chemical action commences, and the acetous or putrefactive fermentation, prevails according to the contents of the stomach” “If our remedy fails try another for there are no two exactly alike & the judicious physician will discriminate as they are indicated” Among the astringents should be mentioned the rose willow It is one of the pleasantest astringents & is a popular remedy in canker It seems to combine a mucilage Almost any of our wild willows may be used Nitrate of silver may be used It is often however difficult to touch the ulcers and we may then use astringent washes. Rhus glabra and R [typhina] are good astringents vide hosp. [illegible] sub. [illegible] The poison of R [vernex] I have more than once known communicated in more than one instances by using the wood as fuel. I recollect a man’s [illegible] to me on account of an eruption on his legs. I told him he was poisoned. He replied that there could be no cause for it but a pair of the pantaloons lately dyed black. Upon investigation I found that the poison species of sumack had been used by the dyer by mistake for the common one. Young persons are more 102 Cold bathing is sometimes advantageous tepid is seldom proper Electricity has been used. I have seen little benefit from it Setons, issues, tartartar emetic ointment along the spine & other modes of counterirritation, are employed & may be advantageous but where the irritability is great they do injury If the disease is not translatable it is made worse by counterirritation In the treatment of patients affected with this disease, we should bear in mind, that they are the subjects of great mental sensitiveness & irritability The presence of strangers in injurious & the remarks of bystanders upon the patient may cause an amount of mental irritation little suspected. I have succeeded in curing chorea by elaterium though this is an article not mentioned by writers as applicable to this disease. A young man debilitated by confinement as a clerk in N. York was thrown into convulsions and derangement of mind, by a sight of distress while on board the packet for this place Elaterium was given to prostrate the system & break up the habit. It was successful & this led to its employment in chorea. I have completely broken up the latter disease by an eighth of a grain of elaterium & this is the only case which I have broken up vide end of this article Case a female delicate 14 yrs of age had not menstruated had been treated with cathartics, epispasmodics and narcotics, which palliated the symptom. The patient then took arnica for 10 or 12 days beginning with moderate doses (zii to a pint of boiling water being given in 24 hours) & increasing to I have found [illegible] which however was Dr [Rush’s] favorite remedy in females about the cessation of the [illegible] useful Friction antispas. electricity etc. had merely palliated The case then [illegible] to indicate tonics [illegible] the other remedies had [illegible] effect or not recovery rapidly upon bark Sometimes connected with pneumonic affected or with [organic] eff. of the heart In some of these cases [illegible] of copper 1 to 3 gr. rarely more than 2 gr. nauseating article [illegible] in such cases more especially As the [disease] advances sometimes [illegilble] difficult [illegible] swallowing dark [tongue] # [illegible] of them the book pedlar and [Minot] [Sheri] [illegible] [illegible] Both these had this facility in [calculating] # At this time there was not excitability enough left to enable the elat. treat. El. shd not be cont. more than 103:a Ulceration of the mouth in children This is sometimes a troublesome complaint and one that does not readily yield to remedies. It is commonly called canker. The complaint consists of one or more ulcers, which commence with an inflamed point or with a white slough situated commonly near the frenum but sometimes extending over the whole inside of the mouth. The edges of the ulcers are inflamed & elevated & their surfaces excavated, as if they had been eaten out with caustic. The child drools much and nursing is evidently very painful to it. A febricula attends the first stage. The bowels are slow and digestion not vigorous indeed the complaint often arises from improper food and is connected with that state of the stomach which causes acidity Treatment. First excite action of the bowels by magnesia, if there is acidity, blue pill, if there is torpor, or calomel grii & chalk grvi. After this give tonics & astringents as Moseley’s tonic solution 3 to 12 2 to 10 gtts 4 to 6 brak compound tinct. vitriol 4 to 5 gtts & the vegetable astringents as geranium in a [ter] spoonful of water statici spriaea cornus etc. a little laudanum may be added For topical applications we may use the vegetable astringents just mentioned, catechu, kino etc. or the following which has been recommended as very efficacious RX sulph. cupri grs x, cort. peruv. zii acad. gum zi mellis et aquae aa zii make a soft paste to be applied to the ulcers with a pencil. A weak wash of corrosive sublimate may be used Sometimes a mild caustic is serviceable, as nitrate of silver A wash of opium or of opium & corr. sub. is sometimes the best viola pedata makes a valuable wash. Asclepias tuberosa is escharotic. [Post] [illegible] case affected by this poison than old. When young I have often been poisoned myself by boing near the plant merely. Now I can brush past it with impunity provided it does not touch my hands or face. Some persons are not affected at all. The uncertainty of its operation is the only reason why it is not used in medicine. Corrosive sublimate is a good application for the affection of the skin. Yet the disease is a specific one and must generate run through its regular course. A similar disease is produced by the oil of the shell? of the cashew nut Ulceration of the mouth continued “The disease sometimes attended with severe pains, as severe as in tooth ach in which case opium is serviceable. Case of an adult use veg. astring. copper, zinc, opium, nit. silv. & at last corros. sublimate. This last would not be safe in the case of children. Intense pain was produced, which was remedied by holding it in the mouth There was a profuse salivation but it soon ceased and the disease was entirely removed. The surface of the ulcer was destroyed by the sub. & the dis. being local this effected a cure # I have turned my attention particularly to the question whether cal. produces it. I have known the dis. to allow dysentery It was an old notion that cal. broke down the crasus of the blood and it produced a tendency to gangrene. But in the venereal wards of hospitals you will see patients with sloughs all over the mouths and yet no gangrene 104 Gangrene of the mouth This is not a primary disease but a termination of other diseases making its appearance soon after their abatement I have known it follow dysentery and other affections of the bowels, but not any disease in which the blood vessels have exhibited an inflammatory action. It seems to follow diseases of the nerves rather than of the vascular system Children are generally subject of it. This disease is sometimes accompanied with much pain & at others with none ordinarily with little or more. One of the first symptoms is a constant inclination in the child to pick some part of the mouth with the fingers where the gangrene first commences either the teeth gums, less or cheek That part becomes spongy & has a fungous appearance in the course of a few days discharges a [illegible] matter, has a livid appearance & finally becomes black and dry the adjoining parts of the face become tumefied and indurated and the disease continues until a considerable part of the face becomes completely [sphacelated] when the patient dies It may continue sphacelatal in [illegible] etc. the sphacelus being hard dry & black like a piece of leather This disease has been attributed to the use of calomel, but it is entirely unlike that produced by this article, and occurs also in cases where no calomel has been given. # In those cases where calomel has been freely given the disease is not so apt to occur vide case 4th I have known a similar affection occur in the leg of a child, & an irritative fever preceded by rheumatism. Commencing with a spongy and orange coloured spot which afterwards become hard & black, the gangrene livid purpled as though the blood had settled pulse small not much disturbance of the circ. syst. except that it was large # & Prof. Smith & myself could not get down much medicine and were obliged to [illegible] [illegible] with external applications We [illegible] injections and a great variety of external application blisters “When the disease appears with tumefaction I think leeches might be of service. This was called by Dr Smith congestive inflammation. In other cases of gangrene, leeches would not be of service It is not easy to [class] the operation of charcoal It has been called a tonic, but it does not much resemble peruv. bark and we do not gain much by classing it with it It seems to act by generating an excitability Charcoal shd be made of soft wood or of lamp black burned over again in crucible, as is sometimes done by the apothecaries 105 extended up the leg and the child above the knees on both sides died [illegible] No applications seemed to have any effect. The child was irritable & The disease under consideration is nearly allied to that called swelled tongue, but the latter oftener attacks quadrupeds The treatment should be stimulant & antiseptic. Acrids as capsicum may be used & the arum triphyllum accidentally has been known to cure. In one case which I shall relate charcoal appears to have effected the cure. Case 1st The first patient that I saw affected with gangrene of the mouth was an adult female who had the typhus fever. The gangrene commenced on the inside of the cheek & when I first visited the patient a portion of the cheek as large as a dollar had sloughed off out? Great part of the food taken into the mouth passed out at the hole in the cheek. The patient continued in this state for eight or ten days & then died The attending physicians informed me that she has received the ordinary treatment for typhus fever. Case 2nd The next patient affected in a similar manner was a girl seven years of age. Previous to the gangrenous affection she had had a most excruciating disease, which affected the knees legs and bowels I have called it nervous rheumatism & shall notice it in another place. For this she had taken large doses of purgatives 106 calomel & opium, with diaphoretics & tonics. In three or four days the pain ceased and the fever almost entirely disappeared. The guns presented no symptoms of salivation & there was no increase of saliva. In five or six days after the fever subsided the patient complained of severe pain situated in the right temple & extending down to the shoulder like that which had been in the extremities. This was removed by opium to complain of the teeth Soon after she began to work at the molar teeth of the upper jaw, on the right side, at the same time she had a cough which was accompanied with an expectoration of white viscid mucus, and the breath became very offensive, resembling the effluvia of an anatomical room where subjects have been kept a long time. The appetite was tolerable, however the patient took animal food, with relish, and the bowels were easily moved with a little rhubarb the patient world at the teeth until she had removed two of the molar teeth with her fingers, she still continued to pick at the gums. The cheek of the side affected became hard, swollen & red. In forty eight hours a black spot appeared in the centre of the swelling. This spot the patient immediately began to rub with her fingers & soon made a hole through her cheek. The gangrene continued to extend, for a week & at the end of that period had proceeded as far back as the angle of the jaw affected the throat & perhaps the aesophagus The patient then died, having taken food and medicine will until within forty eight hours of her death. 107 Peruvian and oak bark, opium & camphor were very freely given the affected side of the mouth between the teeth & the cheek was filled with superfine bark & poultices of bark were applied to the face In the last stage affected perhaps the lungs Case 3rd Another case occurred in [illegible] subject a child etc. A female child, about 5 years of age was attacked, in the winter of 1813 with “constipation with fever” the complaint being principally confined to the bowels The attending physician gave a dose of calomel and worked it off with senna and manna. A considerable quantity of matter was discharged from the bowels, but from its appearance further evacuations were deemed necessary, and several doses of castor oil were given. On the fourth day I was invited to see the patient. I found her with considerable fever of the typhoid grade, attended with pain in the bowels and head. There was also some swelling of one cheek & the child complained of one or two of the double teeth of the upper jaw on that side. These she frequently attempted to pull out with her fingers & finally succeeded in extracting one of them The cheek afterwards became swollen, inflamed, and hard to the touch & in a short time an orange coloured spot, appeared, upon the outside near the centre, which soon became livid, and the gangrene spreading rapidly, the child died, in eight days from my first visit. She became delirious previously to the cheek becoming livid & afterwards, was comatose. In this case the disease seemed to affect the brain as it does in some cases Bark, opium and camphor were truly given & antiseptic 108 poultice applied to the face as bark [illegible] [fermenting] [poultice] Prof. Smith saw this patient soon after my first visit & agreed with me in the opinion that the case would terminate fatally. He informed me that he had seen but one case of the kind before & that he had attributed that case to an injudicious use of calomel After seeing this patient however, he considered his former opinion as incorrect since in this case there were no marks of the effects of calomel & there was no probability that the single dose of calomel, given in the commencement of the illness, could have produced such an effect, especially when repeated doses of other cathartics, had subsequently been given & had operated freely 4th Case. The next case which I met with was that of a female 12 or 13 years of age, who had the dysentery, in the summer of 1815, accompanied with much typhoid fever & rather a larger discharge of blood by stool than is common in dysentery. The child had been sick for some days before a physician was called. I did not succeed in my attempts to determine the diseased action from the bowels to the surface by diaphoretics & the warm bath, & the disease ran its course and nearly exhausted the patient When it began to decline, the stools to present a fecal appearance & the appetite to return, the friends were There had been some aphthae and I was on a careful watch 109 much encouraged I, however, began to expect a fatal result for I observed, between the anterior incisors of the lower jaw, a fungous enlargement of the gum, the apex of merely a slight discoloration [illegible] & swollen between two teeth which had a purplish appearance somewhat as appears in salivation sometimes. I apprehended gangrene in the case (perhaps from the countenance) and on the first symptoms of it informed the parents, who however, could see nothing alarming in the small swelling between two of the front teeth. I began early with oak & peruvian bark, and at the same time gave freely of brandy and porter. As this course had no effect I applied bark and diluted sulphuric acid to the part affected & also covered with the lunar caustic. Still the treatment had no good effect the gangrene extended under lip and chin became black and the child died Case 5th A child about 3 yrs of age cousin of the previous one [illegible] had a dysentery, in the summer of 1815 [illegible] as there was another member of the family sick in oil uncommon & interesting manner viz the case of chorea resembling hydrophobia was much neglected Her fever was typhoid & the stools sometimes bloody and sometimes of a green mucus. After a course of 15 days and amendment in the symptoms took place the stools became less bloody, the green stools more rare & though the patient was extremely weak but no reduced low as the previous one, the appetite returne After convalescing gradually for six or eight days, there came on a samous discharge from the nose, small in quantity but very fetid which reminded me of gangrene # In this case I examined the gums to see if there was any appearance of salivation and found the gums etc. Two teeth and a piece of the alveolar process came out The disease did not spread so rapidly as the other ones In addition to bark, tonic solution etc. I gave charcoal 110 of the mouth which I had not been on the look out for AT this period the patient inclined to keep her fingers I her mouth. # The gums were very clear and bright & adhered firmly to the teeth, except on the left side of the upper jaw, where the gums of the biscupides appeared discolored and discharged a samous matter. I declared the parents that in my opinion the case would terminate fatally. The child complained of pain in the face and teeth. The cheek opposite the teeth became swelled and hard and of an orange colour. I declared to the friends that mortification had taken place 7 pointed to a black spot on that cheek which happened however to be accidental. I was mistaken for the next day it was found that the black spot was produced by a piece of burnt apple skin, which was washed off This encouraged the friends; yet within 24 hours sphacelus took place the apple skin was in the very spot where I had supposed that I had seen it. This gangrene ceased to spread after the spot became as large as the end of the little finger A circular piece sloughed out and left a hole in through the cheek of about a quarter of an inch diameter The disease abated, the affected teeth and a piece of the alveolar process came away the lips of the wound produced by the sphacelus healed up & the child recovered I recommended the same treatment in this case as in the preceding, but having no confidence in it, & abandoned it and gave charcoal to the amount of perhaps a pound or a pound & a half a day I h ad pudding made of half charcoal & half flour, sweetened with molasses & sugar & fed to the child for the appetite was good. Tonic solution When the disease commences of itself # At the time when the disease called the scalled tongue was very prevalent affecting cattle principally with swelling of the tongue & salivation but to some extent human beings with swelling of tongue cheeks etc. It was found that acrids as [arum] were the best remedies pulse 120 tongue then [brown] fur, considerable pain 111 and compd tinct. vitr. were also given & I commenced the treatment with white oak & peruvian barks & yeast poultice. I attribute the cure, however, to charcoal. Case 6th This was an idiopathic affection. Martha Denison a delicate constitution about 12 yrs of age was attacked in 1819 with symptoms of gangrene of the mouth. There was severe pain in the teeth and jaws oppression at the stomach and symptoms of fever. I discovered the purplish spot in the cheek & “the gums soon put on a spongy appearance” In this case I commenced the treatment with an emetic, which operated favorably I gave it to [illegible] the excitability of the system & gave relief. I then gave stimulants, bark, brandy & opium & kept in the mouth between the gums and cheek a paste made of powdered bark wet with brandy and laudanum. The patient recovered, but the two front teeth of the lower jaw became very loose and there was occasional pain & suppuration for nearly a year. It was about a year before the teeth became firm. [Superfine] bark was occasionally used. Case 7th In 1820 I visited a black child in the last stages of this complaint. At the time when I saw it, it could not swallow. It lived however in this situation for several days I have seen several children in the latter stages Even if there is no chance for a cure it si desirable to be able to give a correct prognosis Trouble has sometimes arisen from the opinion that such cases were produced by calomel A student of this school in [Litch.] cty from notes of my lectures It is known by an [illegible] swelling in the throat some fever etc. etc. In some seasons it prevails extensively & affects persons of all ages. In some seasons these diseases which are called contagious affects one description of persons in another another owing to mode of life etc. “It rarely affects a person the second time. It is said that if it affects the parotid of one side only it may occur again” I have treated cases of this disease with great anxiety. I have never known cases of greater irritation than from this disease “It is milder in children than in adults & is seldom translated to the mammae or testicles till after puberty” “Sometimes the swelling of the testicle is simultaneous with that of the parotid gland or [previous] I have seen several such cases” “The first symptom observed is sometimes a soreness of the testicles. They at length become 4 or 6 times their natural size a suspensory bandage will be necessary” “In some cases there arises suddenly, [illegible] pain in the head pulse full and tense eyes red & all symptoms of phrenitis” 112 Cynanche parotidea Mumps This disease is an inflammation of the parotid glands & is generally moderate in its symptoms Sometimes however it is translated to other parts & is then a severe disease endangering life. It is milder in youth than in adults & in general it is only after the age of puberty that it is translated. The parts to which it is translated occasionally, are the testicles & the prostate gland in males the mammae of females more rarely & sometimes the brain or stomach I have never myself seen a case in which the inflammation was transferred to the mammae but do not doubt the fact Sometimes it appears first in the testicle or at least simultaneously in that & the gland This disease has been considered contagious In my opinion it is not, but on the contrary is liable to be epidemic. When its prevailed in college, the students who left in order to avoid the contagion were attacked as early and is certainly as those who remained. I have noticed that it made its appearance pretty regularly once in seven or fourteen years The fever which accompanies the severer forms is either of the inflammatory or the typhus grade or may be merely irritative & should be treated accordingly When the testicles are affected they are painful swollen sometimes to an excessive degree & sometimes so highly inflamed as to indicate venesection When the stomach is affected “it puts on crythomatic inflammation” and there is hiccough, subsultus tendinum, irritability of stomach and frequent vomiting. # When the brain is affected there is pain of the head & eyes, with hard and tense pulse When the parotid glands only are affected the # These symptoms may come on after the affect of test. [illegible] continued, some [illegible] begin to subside. Dr Rush observes that applying a blister directly on the infl. prevents the system from being affected. I do think blisters keep the aff. in one part “In some seasons an emetic at the commencement or a blister will prevent a translation” Having [learned] the importance of attempting the breaking up of diseases I cast about one year for means to interrupt it & found emetics quite efficacious Stramonium After the testicles have been affected some time and the affection begins to subside the symptoms sometimes change There is subsultus tendinum the stomach become affected vomiting is frequent with hiccough etc. In this case apply mustard to the stomach & feet etc. 113 a generally mild and more inconvenient than painful A translation makes it worse; more so when the translation is to the stomach than to the testicles & most of all when to the brain. Sometimes the complaint is very severe, the fever lasts three or four weeks and the patients are many years in recovering from the disease Treatment. The disease is often broken up by an emetic in the commencement It is best to stop it in the first stages if possible. Mild applications to the inflamed parotids we generally sufficient, such as ammonia or volatile liniment. Dr Rush however recommends blisters to the parts affected, in order to prevent a translation. When the disease effects the testicles & give emetics and apply discutients to the local affection. I also apply blisters to the inside of the thighs. They relieve the testicles when they are swollen & prevent translation to the stomach For a discutient was we may take the following Rx mur. amm. ziii; camph zi; brandy or vinegar 1 gill; water 3 gills. When the inflammatory action is high, bleeding may be practised. It will be well also to use a suspensory bandage. If the stomach is affected in the manner above described we have a difficult case to manage. Epispastics must be applied to the scrotum, counterirritants to the epigastrium to ally vomiting, with effervescing mixtures internally for the Ether is best given in effervescing mixture (carb amm. & lemon juice) Carbon ac. makes stimulants more diffusible & hence causes them to be [used] gratefully and often to be well borne when otherwise the would not be Case 18 grs plethoric parot. gland & testicles swollen head affected Relieved by bleeding decidedly entonic the only entonic case which occurred In the progress of his case stom. became very irritable abdomen sore & tender excessive irritability Did not recover his health completely for years was left dyspeptic & with nervous irritability. To correct irritability of stom. lem. juice [illegible] is most grateful add [doses] of aromatics lime water also external blistering etc. Tonics or metallic tonics myrrh asafoetida (nervine also) hops lettuce These cases are so obstinate and will give you an opportunity to try a great variety of remedies cajeput oil on sugar ol. valerian Though the cases may be apparently alike yet you may find one article best for one & another for [another] A very distressing hiccup, accompanied with spasms might have been mentioned in connection with the vomiting give ether lavender cajeput oil also & valerian which are called terebinthinates 114 same purpose diffusible stimuli as ether given to rouse the system opium ipecac, as tonic stimulant, diaphoretic & nervine 7 finally to allay irritation of the system in general antispasmodics as castor & counterirritants to the extremities effervescing mixtures absorbents, also, as chalk & magnesia, cathartics cantheride & occasionally emetics may be indicated. When the brain becomes affected, the lancet should be freely used, cupping, leeches & blisters, applied to the head of the neutral salt given as cathartics Antimonials nit. [illegible] cal. & neutral salts # Some cases will require a vigorous antiphlogistic course of treatment, others with typhoid fever will require in the [illegible] a stimulating & supporting one, while others again will have symptoms of irritation chiefly & require a corresponding treatment In the progress of the disease uniform perspiration will be valuable Angostura serpentaria, qualified with cardamom or cubebs The old writers recommend also [contrayerva] I have much used it atonics of a peculiar character resembles much agrimonia eupatoria which I have used for it in the country where it is easily obtained the latter is non astringent # “Cold to the head and warmth to the feet avoid mental irritation recovery is usually speedy adults most liable to this translation” I consider [quinsy] an affection of the mucus membranes and [tonsils] nearly allied to catarrhal aff. There is a catarrh aff. nearly allied in which there is a thickening of the membrane. This diathesis may also run into croup Good classes angina maligna with quinsy Here is the evil of nosology For scarlet fever gradually runs into quinsy. We must have science and nosology but still we ought to know the errors which nosology is apt to lend [illegible] & the imperfection of science I have the advantage of not [illegible] having seen the disease but of having had it myself often [illegible] with an unpleasant sensation a relaxation a disposition to hawk and throw off [illegible] In this stage it may certainly be cured After the symptoms comes on swelling, or moderately succeeding to this a chill then swelling with pain perhaps extending to the [illegible] The tonsils enlarge The fever is considered enteric or a common but unless among the labouring men in the country it is more usually subacute One tonsil is perhaps more enlarged than the other perhaps one goes on to suppurate & the other becomes of the natural size and appearance The uvula and fauces swell and respiration and deglutition are prevented. Sometimes ulcers from at first upon the tonsils. Examine each case and do not be too positive in calling it quinsy for this & scarlet fever do blend These symptoms continue 2 to 36 or 48 hours I do not know that I have ever seen a fatal case of 115 Cynanche Tonsillaris Quinsy This diseases has been called “I include also under the term quinsy all effections of the upper part of the aesophagus and pharynx which resemble quinsy in their grade of action” Quinsy is an inflammation seated in the larynx glottis & fauces The characteristic symptoms is swelling of the tonsils Sometimes it is seated lower down in the pharynx than the tonsils, but this does not alter the nature of the disease In some cases it is complicated with catarrh. Those who have once had this disease are very liable to a return of it “The disease common at the age of puberty that before or after” Quinsy may be divided into two stages 1st Predisposing debility indicated by relaxation of the uvula and tonsil, irritation about the fauces, weak deglutition, general languor, with cold chills and uncommon sensibility to cold. This usually continues from 3 or 4 to 12 hours the progress of the disease being sometime rapid and sometimes slow 2nd As the disease advances we find, soreness, pain, redness and swelling of one or both of the tonsils & an inflammation of the mucous membrane of the pharynx; deglutition in exceedingly difficult; there is a severe cough & especially a spasmodic one upon taking food or drink, there is much heat about the throat and about the head & sometimes pain in the head, with a pulse so full and tense as to indicate bleeding. Sometimes there is an excruciating pain in the ear. “rarely cough unless complicated with catarrh” This stage may continue three or four 3 to 7 days days. It terminates either in resolution, or suppuration. of quinsy though I have seen many that I thought would prove fatal. I have known a patient continue unable to swallow for 3 days and yet recover When however it is in the form of swelled tongue it may prove fatal. “An entonic fever may attend, with fullness of pulse much headache excruciating pain extending to the ear; but for more commonly at least in my practice, the pulse is little affected, and the disease is almost not entirely local” # riding on horseback and having the snow melt on his throat & [conduct] off the [caloric] rapidly # and shd carry a piece of alum in the pocket “It is important to distinguish this disease from roseola (scarlet fever) There is an erythema of the fauces distinct from both which yet may terminate in either [illegible] The diagnosis is generally easy but there are cases where it is extremely difficult & indeed there is no definite line believed the two especially in the first stages We must bear in mind that quinsy is commonly more inflammatory that it is not apt to ulcerate & we must be guided somewhat by the prescribing epidemic 116 The suppuration is generally in the tonsils, but in some cases where the disease is seated lower down, a part of the aesophagus suppurates. “The tonsils often remain permanently enlarged” Causes. Quinsy occurs must often in the latter part of autumn & in winter. It is caused like catarrh by alternations of heat and cold by exposure to cold & especially by exposure to cold storms of rain or snow. # Sometimes it is connected with dyspepsia & it may be brought on by irritating substances, as acids, acting upon the mucous membrane of the stomach. I recollect a case of a young man who was attacked with a severe quinsy in consequence of drinking freely of cider made cold with ice Persons who are subject to quinsy should be very cautious about exposing themselves to the alternative of heat and cold # Diagnosis. This disease has sometimes been mistaken for scarlet fever. It is not difficult however to discriminate between them by attending to their prominent symptoms the quinsy being as inflammation of the mucous membrane etc. The first stages however of scarlet fever, resemble those of quinsy, and the difficulty of discriminating between them is at that period much greater. In deciding upon any particular case we must be governed by somewhat by the nature of the prevailing epidemics Chewing camphor will also but not so well break up quinsy in the forming stage but chewing this article is apt to produce pleasant symptoms in the stomach and head Other stimulating applications would probably answer as [guaiacum] & any alcoholic tincture “The prophylactic plan of carrying alum in the pocket etc. has succeeded in hundreds of cases. Indeed when called in the latter stages I often tall them I can do little except to prevent it in future” When the dis is fully formed and when there is much pain in the neck running up into the [illegible] fomentations and the vapour of warm water, the steam bath by throwing over the patients head a blanket and having a teapot of warm water A blister also in the above circumstances will relieve the pain and give great relief An emetic also will be often very beneficial in the commencement of the second stage There is often an excessive quantity of acid in the stomach Case A young man in very hot weather [illegible] a large quantity of cider made very cold with ice was taken at night with great pain and difficulty of swallowing The patient was very anxious to be cured that night A large quantity of tartar emetic was given in excessive doses until a severe orgasm was produced then seeing to [illegible] stricture of the upper orifice of the stomach the [illegible] & secreted from every pore from the violence of the action of the system finally he [illegible] away, and continue in syncope for 10 or 15 mins came out of his fainting fit, the tart. ant. acted as a cath. and the patient was entirely relieved of the difficulty of swallowing [illegible] was merely feeble and exhausted from the prostration of the [tart] 117 Treatment In the first or forming stage. Quinsy may be easily broken up by keeping a small piece of alum say of the size of half a pea in the mouth, and swallowing the saliva until the symptoms have left. Various other astringents may be useful in the first stage. I have given the astringent barks and bitter roots, catechu etc. & have also combined with them the mineral acids chlorine etc. “But all these things will be injurious in the 2nd stage” When the disease if farther advanced a more energetic treatment is necessary. If the tonsils are largely swelled astringents will merely aggravate. IN this stage it may often be broken up by a strong impression made by nausea and vomiting. A strong emetic 3 grs tartar emetic with 8 grs of ipecac # may be given & when the disease arises from a chronic affection of the mucous membrane & acidity of the stomach, an emetic will remove it. In one case I gave half a grain of tartar emetic once in 15 min. until the system was affected, I succeeded in conquering the disease. The patient was in extreme pain & exhausted he fainted previous to fainting he was unable to swallow after coming to, he could swallow & the disease was removed. “But if the case has advanced a little farther, emetic will do no good”s Gargles will in general do harm rather than good, where there is much inflammation. If the irritability is extreme mucilages may be given, and when there is great difficulty in swallowing a cloth wet with spirit and water ay be applied over the mouth and nostrils. Cold water applied externally & internally has been recommended but is dangerous. It may be used however as a preventive. # Eupatorium etc. I have known some phys. generally successful [illegible] breaking up quinsy with cold water but as I predicted there was danger of the translation to the brain he lost one patient in this way “It may be used as a preventive” When the trails are much enlarged it is customary to bleed I would bleed it there was much fullness and strength of the pulse I have often bled and seen it done without the beast benefit still however without any injury as I could perceive “V. S. is important when there is danger of affection of the brain” Scarifying is generally practised. It is sometimes beneficial but often it increases the disease as is the case when a boil is scarifyed I do no t know that I can point out the circumstances which it is beneficial but if there is much irritation I think I would not scarify I have often had my own throat scarifyed without benefit Perhaps it is as often as once in 20 cases that the disease proceeds to suppuration. But if you puncture the swelling be careful to see where you introduce your lancet Case of [young] an opening was made which subsequently caused a troublesome sore the swelling burst of itself In various cases astringents was useful Lister’s [scoriae] (devils bit button snake root) it acts a little like seneka stimulating the fauces it operates considerably in a decoction It has been much used not of much consequence I have not much confidence in gargles The patient cannot gargle But you will give great relief by washing out the mouth with warm water or with mucilages or with a little old spirits and water which is very grateful to the patient Wash off the [illegible] which [illegible] Great advantage is derived from injecting with considerable force with a syringe & washing on the parts Spirits & water will be grateful & reviving 118 When there is redness and swelling but not extreme irritability, scarification is beneficial. If there is irritating soreness or inflammation scarifying will aggravate it After the inflammatory stage is past, blisters may be used I have not been successful in scarifying Bleeding may be necessary, if so it will be indicated by pain in the head and a full & tense pulse. When suppuration is about to take place poultice may be applied externally & vapor inhaled The latter remedy may be administered, very well in the following manner. Put a vessel of hot water in the bed, by the side of the patient & cover him with a sheet. # Touching the tonsils with nitrate of silver, is highly useful If the ear is affected, wet a piece of cotton with strong ammonia and apply it to the dear. it produces a pungent sensation and often gives relief The [liatris] scariosa is used in quinsy in the form of a decoction of the root. It is expectorant, diaphoretic & diuretic. It is called “devils bit” “After the inflammatory stage is established apply blisters” “If the irritability is extreme apply mucilages” “[illegible] & diaphoretics have been used in the early stages and are undoubtedly serviceable” # If you cannot well distinguish where suppuration has taken place, you had better not attempt to open the tonsils When the swelling is great poultices are very beneficial Dove’s [Dury] poultice Devils dung asafoetica Album graicum blown through a quill!! much used by my predecessors in this place Cathartics are proper early in the disease neutral salts if the fever if phlogistic Diet & regimen Give while the patient can drink, nitrous ether & water or a acidulated drink etc. Feed with arrow root etc. for the diet When the inability to swallow has continued sometimes the action is not enteric & the patient shd not be bled nor exhausted by cath. The disease is at this time principally local & from want of food etc. the pulse becomes feeble spirit and water injected into the throat will bring grateful and reviving [illegible] exhausted patient “Apply poultices keep the bowels open with enemata” “Inhale vapour of ether” Various gargles are recommended such as chlorine muriatic acid & water etc. but when there is much action they are apt to irritate Camphorated gargle vapour of camphor etc. There are a variety of these things which are mere palliatives The difficulty of swallowing is not caused so much by the swelling as by the soreness and pain for I have seen patients declare themselves much relieved and able to swallow when upon looking into the throat I could perceive no change in its appearance 119 “Scarification is recommended but I could never succeed with it. If the disease were pure inf. scarif. would be of service but it is an irritation infl. & scarific. increases the pain & infl.” In [illegible] case a free scarific. made the case worse in every respect” There is a stage when scarifying is beneficial when there is redness & swelling but not extreme irritability” “Leeches have been applied in the inflammatory stage externally and to the tonsils. It is difficult to make them take hold on the mucous membrane, but they would be more effectual there” “Suppuration does not take place in one tenth part of the cases. There is free secretion but no solution of continuity upon extermination” “When suppuration is likely to take place use poultices and inhalations of vapour poultices of bread and milk with stramonium are serviceable Gargle or syringe the mouth with spirits & water or camphor” “When the disease is seated farther down in the larynx it is essentially the same” “White dry pigeon’s dung in a poultice with bread and milk was used by Dr [Monson] He thought the phosphate of lime of service” I prescribed it in one case and they mistook for it devils dung (asafoetida) & it did wonders. I did not tell them of their mistake” [illegible] state of fever is a better classification than Good’s. Good separates the disease under different classes making one part are [illegible] disease another an aff. of the blood vessels “Scarlatina & angina are sometimes considered as separate diseases, but they seem to be only different forms of the same disease” 120 Scarlet Fever This disease has been called by various names, among medical writers, though the popular English appellation has been scarlet fever with little or no change. Canker rash however has been its common popular appellation in New England, until of late. Under the name scarlet fever I include both scarlatina mitis & S. maligna & likewise the paristhmitis maligna or ulcerated sore throat called also malignant sore throat & malignant quins. Other names that have been given are Scarlatina mitis & maligna cynanche maligna paristhmitis maligna scarlatina anginosa Enanthesis rosalia is defined by Good Rush a scarlet flush appearing about the second day on the face neck or fauces; spreading progressively over the body; and terminating about the seventh day; fever a typhus. This author divides rosalia into two varieties simples or mild scarlet fever which he considers as being slightly contagious & paristhmitica with an ulcerated throat & a rash not so regular as that of the other variety. This he calls highly contagious Under the name scarlet fever I included both the common mild scarlet fever with a rash & nothing more and the most malignant forms of ulcerated sore throat with the intermediate varieties considering them all as being but different degrees of the same disease This disease with its varieties a naturally associated with pneumonia quinsy influenza etc. Quinsy is an exception persons who have had it are more liable to another attack So too in tropical climates even have what is called a seasoning As a matter of fact this disease is theoretically considered contagious practically not so no precautions being taken the patient not being separated nor the friends and neighbors refraining from coming “The notion of contagion may sometimes be useful in keeping away idle visitors case in Guilford” 121 Scarlet fever often appears as a sporadic and sometimes as an epidemic disease. In general it affects children and women more than men. Dr. Rush’s opinion Some say that the disease never persons over 40 years of age. When epidemic however it attacks persons of all ages, though even then the majority of cases are among children and persons of delicate constitution. In general persons who have once had the scarlet fever are not attacked with it again, still this rule is liable to many exceptions for I have known repeated instances of a second appearance of the disease in the same person. This partial security from a second attack is met with in various epidemics & we may say in general that a person who has had any one of several different diseases the same general diathesis is less liable to have another Scarlet fever is said to be contagious especially in its severer forms The fact is disputed but this is the general opinion. Some fevers are perhaps contagion & among them some forms of this may be so. It certainly, however appears to follow the laws of epidemics and I am inclined to think that the facts which have led to the opinion that it is contagion are better explained by reference to those laws. It is said sometimes to go through the country like the influenza. Like other epidemics, those of scarlet fever exhibit appearances in different seasons, being sometimes milk and harmless & at others highly malignant & dangerous It has occasionally been as # And because blisters applied produced mortification It swept off whole families The fever considered a typhus It is not always so It is sometimes [sub-entonic] always however of a typhous grade 122 as the plague. About a century ago this disease prevailed in this state in its most malignant form, sweeping off whole families. It was called the black canker because the sloughs in the throat turned black & this name, though the influence of tradition, inspires terror in this town even to the present day Since that period the disease has probably been growing milder up to the present time. In 1794 however it was very severe in this town in Litchfield county & over the state more malignant than it has been since. Subsequently to that period adult males have been less affected. The last severe epidemic in this town was in 1803. Though sometimes attended with inflammatory symptom. Scarlet fever as a general rule, is of the typhoid or typhus grade & when malignant puts on the form of typhus gravior or gangrenous state of fever Symptoms. This disorder, when not malignant, nor irregular, commences with ordinary febrile symptoms general disturbance of the functions of the system, chills alternated with flashes of heat & pulse in most cases frequent and soft In severe attacks there is much nausea, sometimes vomiting, pain in the head back and limbs & great prostration The tongue of strength. In 1803 the disease frequently commenced with pain in the teeth or in the ear is the first symptoms In the progress of the disease there is more or less tendency in proportion to the violence of the disorder. In severe cases there is often great heat and dryness of the skin & perhaps the color mordax. In such cases also we frequently with an acrid discharge from the eyes & “When delirium is present it arises rather from inanition than repletion IT is accompanied with subsultus” Swelling of the tonsils is rather a favorable symptom Swelling and suppuration of the glands in the neck haemorrhage for the [illegible] & petechiae may occur 123 nose which excoriates the skin wherever it touches. Irritability of the stomach & vomiting are common & sometimes there is a troublesome diarrhoea. Petechiae may make their appearance. Case at [Hotchk??] town Haemorrhages sometimes take place; & in case of heat on the surface and what Armstrong calls congestive state of the system, a slight haemorrhage from the nose will be beneficial. Finally in the ordinary malignant forms of the disease the breath is very fetid. The epidemic of 1803 was characterised by great irritability of the stomach vomiting & diarrhoea pulse very low and feeble. In this epidemic after obviating the inverted action (of the stomach) stimulants were indicated. The throat is more or less affected from a slight redness to a deep slough. Sometimes there is a high degree of inflammation of the uvula & tonsils at others a relaxation indicating astringents both conditions accompanied with a high degree of tumefaction. A common appearance, in the commencement of the severe form of the disease is that of a white coat upon a part of the tonsils In the progress of scarlet fever, the affection of the throat may be more or less troublesome. It often terminates in ulceration & sometimes in gangrene In three or four days from the first appearance of febrile symptoms or rather on the second day of the fever the eruption appears in the form of a fine rash as described in the definition. In about as many days from its appearance about the seventh day of the disease it disappears Peculiar dulness of the eyes hollow sound of the voice patient appearing much like a night walker The first case of the kind which I saw I had no doubt about The friends had doubted whether he was sick enough to send for a phys. I declared at once that he probably would die. This was a case of pneumonia notha Most resembles measles Ordinarily distinguished readily sometimes with difficulty If scarlet fever is accompanied with a running of the discharges from nose with catarrhal symptoms, and is somewhat distinct in its eruption (hard under the touch under the skin) and such cases occur it cannot be distinguished from measles except by the general character of the epidemic I used to notice in the first commencement of my practice that on the first breaking out of the epidemic the older phys. used to wait and observe several cases before they decided upon the name 124 with branny scales & in ordinary cases the patient is then out of danger. The eruptions, however may vary much & even be altogether wanting the local morbid action being determined wholly to the throat. Ataxic cases will have no eruption. The worst cases of scarlet fever are those which transcend ordinary febrile action. In these the patient is scarcely sensible of being ill, appears dull and languid, his countenance indicates torpor of mind, he has little irritability of mind and is indifferent to surrounding object, his extremities are cold & his pulse small frequent and feeble & perhaps intermitting. Upon examining the throat ash coloured sloughs are found upon the tonsils and uvula. In these cases life is extinguished without any reaction of the system in the course of 24 or 48 hours, unless the tendency to death is obviated by the most powerful treatment. These ataxic cases resemble the ataxic cases of yellow fever pneumonia typhodes etc. which have sometimes been called walking cases The scarlet fever is liable to be confounded with measles, the disease which it most resembles. The marks of discrimination are these. In measles the eruption is less diffused is in pimples or circular dots more pointed & partly distinct & partly in clusters & the pimples produce a palpable roughness of the skin. In scarlet fever the eruption is diffused like erysipelas & consists of innumerable points or specks under the cuticle, intermixed with minute pupulae In some cases the eruption is in irregular patches & in others are uniform flush “Symptoms of pneumonia rarely attend scarlatina” This is one of a series of epidemics. It is usually followed or succeeded by measles & is followed by hooping cough For only it probably existed only as an epidemic now we meet with sporadic cases continually 125 while no roughness is felt, except in a slight degree upon the arm. The two diseases differ also in the time at which the eruption appears. In scarlet fever it shows itself upon the face and arms on the second day, but in measles it is not seen upon the arms till the fourth day. The scarlet fever is distinguished also by the absence of the catarrh, cough & determination to the lungs, suffusion of the eyes & the red and swollen state of the eyelids, which generally attend upon the measles. The latter disease also is generally accompanied by an inflammatory fever instead of the typhus which characterises the former. Still these two diseases of ten blend together so as to make the discrimination very difficult. It is barely possible that they are the same disease, though it may be objected to this view, that scarlet fever likewise is occasionally seen to blend with influenza # Epidemics of influenza are followed by [measles & scarlet] The prognosis in this disease will be obvious upon attending to the malignancy or the severity of the symptoms. In its severer forms it is always a dangerous disease & in its highest malignancy one of the most fatal while in its milder forms there is but little danger. # It is sometimes difficult to determine whether a particular case should be considered as one of scarlet fever, or of quinsy A case of scarlet fever in which there is no eruption & the tonsils are inflamed &swollen can be distinguished from one of quinsy only by attending to the state of the pulse, the prevailing epidemic etc. I have known it appear as an epidemic when it required nothing more than nursing One idea which I wish to impress particularly upon your mind, is that you must investigate the particular epidemic which you have to treat for no previous one will probably have been similar 126 The treatment of this disease must vary according to the diathesis. Epidemics of scarlet fever will differ widely in different seasons & different places & require very different treatment In a country where intermittent prevail the treatment will be different This has been some dispute about using the lancet in this disease. This will depend the degree of inflammatory diathesis. As a general rule emetics are indicated, but not always. Cathartics are generally improper but sometimes are required. In short indiscriminate treatment is as improper in this diseases as in any other. In this milder forms of scarlet fever, we may employ the usual treatment for typhoid fever, & administer those remedies which translate & keep up action and equalise excitement, as diaphoretics, the warm bath etc. For the mildest form it will be sufficient to give mild diaphoretics such as wine whey & elder flower tea, with perhaps a little antimony, acidulated drinks & gentle laxatives As the fever is generally of a typhoid or typhus grade, emetics are of especial importance in its treatment. They affect particularly the mucous membranes and may be repeated in the course of the disease, for the purpose of throwing off the accumulated mucus. The violence of the disease may often be completely broken by an emetic “In some epidemics when there is considerable action cath. of cal. are important especially in intermittent districts Rx cal. & jal. as for remittent bilious fever” “When there is tremor paleness, cold sweats, vomiting diarrhoea, cathartics might destroy the patient We must rouse the patient by counterirritants etc. and then we may go on with the treatment by emetics of ipecac etc. “Dr Rush bled but f.s. is very rarely indicated and in such cases as approach to A. tonsillaris” “Still it [illegible] all forms entonic atonic etc. “If malignant give bark & the min. acids. If the system does not respond give cantharides & capsicum oil of cinnamon cloves or cajeput” 127 at the commencement. All writers agree in recommending them. [Witherin] advises ipecac grs vi & tart. ant. gri for an adult followed by a strong decoction of senna Dr Rush recommends the turpenth mineral 2 to 6 grs with the view of strangling the disease in its birth. Sulphate of zinc is a good emetic & is preferable in the latter stage. It is local in its action & tonic in its effect. It operates speedily and produces less exhaustion. Vomiting by snake root has been practised In the irregular forms of scarlet fever, this practice is more questionable & if emetics are given they must be preceded by stimulants to rouse the powers of the system Cathartics are sometimes needed & calomel is to be preferred The judgment of the physician however must be exercised & the character of the epidemic studied, for great caution must be exercised that the system be not weakened by them & in extreme debility they should be preceded by stimulants. In some epidemics they will destroy the pat.” In some epidemics bleeding may be proper, but the apparent indications for it will generally be better answered by leeches about the throats and [temples] In malignant cases where the powers of life are very feeble no evacuations are to be used. External irritants are to be applied to rouse the system such as ginger mustard brandy a paste of mustard spts. turpentine & aqua ammoniae etc. Internal stimulants must be given Ammonia with bark opium etc.” “Tinct. canth 20 drops once in 2 hours till there is some effect.” “Serpentaria with ammonia acts as a tonic and diaphoretic” Where there is a prejudice against cold affusion with water alone spirits or [illegible] or camphor may be added 128 [illegible] to 4 [illegible] 3 or 4 such as capsicum Capsicum especially when the stomach is debilitated 4 to 5 grs [illegible] Cantharides in 20 drop doses. Ammonia camphor quinine, mineral acids etc. Carb. amm. & cantharides may be given to excite the system & be followed by bark and brandy to keep up the excitement. Diffusible stimulants also may be required, such as chloric or sulphuric ether 20 gtts to a teaspoonful of water for a child. In small children if there is difficulty in getting down medicines the bark may be given by injection, or the body covered with it, by means of a bark jacket. In severe cases, not of the most malignant form, the heat and dryness of the skin are often very great & calor mordax may exist. Cold applications to the skin, especially those of stimulating kind will then be beneficial. The cold bath cold affusion, or sponging with vinegar & water or spirits & water may be used according to circumstances. The cold bath or affusion of cold water may be superseded in case of prejudices on the part of the [illegible] or objections from other causes, may be superseded by sponging the body with vinegar & water If the case is attended with extreme debility and relaxation of the system or if any chills are present sponging must be used & [illegible] with caution. If the cold applications produce a chill or if the eruption comes out irregularly. I should advise the tepid bath to determine to the surface. In the advanced stages of the disease when debility & relaxation are great the vinegar & water should be made tepid & spirits may be added. The rules with respect to these applications are the same as in typhus. In the atonic form of “In children with disturbance of the stomach and pain in the bowels at the same time the eruption not coming out well use the tepid bath It obviates the tendency to convulsions and makes the disease regular In the most malignant forms it is inadmissible” “If there is irritability of the stomach give chloride [illegible] 4 grs 2-3 hours absorbents counterirritants” “In the latter stage of protracted cases emetics of sulphur zinc or copper are very useful” “Withering advises in the typhoid state, after evacuating the stomach & bowels to give senega freely This would be injurious in a malignant case” 129 scarlet fever, the cold bath or cold affusion must not be used IN 1803 I used sponging with vinegar and gave internal stimulants at the same time as min. ac. alc. brandy For children the tepid bath is invaluable in scarlitina particularly in the early stages of the disease and when the eruption is not fully out, or where the eruption is irregular. It is questionable however, how it would succeed in the most malignant form of the disease If there is great irritability of the stomach with vomiting, absorbents and counterirritants are to be used & in malignant cases capsicum, tinct. canth. & care to be given In cases of vomiting saffron & snakeroot If there is much diarrhoea we may give # white decoction with opium, injections of laudanum etc. astringents etc. In ordinary cases, when the eruption has been regular & ends with branny scales, about the seventh day the case is out of danger But when the disease is protracted sulphate of zinc or Moseleys tonic solution is to be given as a tonic. The latter article in a dose from a teaspoonful to a tablespoonful is an emetic in cases of great morbid action. Emetics of sulph. zinc & sulph. of copper have been recommended also of acetate of copper The latter article is also escharotic tonic & caustic. The chlorides chlorates are adapted to this stage of the disease [illegible] [chlorate of potassa] grii to vii “In those cases that require stimulants blisters may occasion gangrenes” “When there is tumefaction of the tonsils use blisters paediluvium & gargle with the mur. ac. especially the [oxymorestic] diluted with 6 parts water” 130 The treatment of the local affection of the throat is of two kinds, external & internal When there is much inflammation about the throat, with the uvula elongated, the tonsils enlarged an inflamed & the pulse full I apply epispastics externally. Blisters, mustard, oil of origanum ol. monard punct. etc. may be applied to the throat Gargles are injurious in bad cases & perhaps of little use in most. Still in ordinary forms of the disease from four to six ounces of any mild astringent acidulated perhaps with muriatic acid may be thrown in by a syringe. The marsh rosemary is considered better than any other astringent. The alum root (henchera amer.) is useful both as a gargle & given internally. For the latter purpose sweeten it & add a little brandy When there is not much tumefaction & considerable relaxation of the parts stimulating garbles are good, as capsicum & brandy astringents may be added. In gangrenous cases quinine is good if it can be got down. In the latter stages of the disease it may be useful to touch the ulcers in the throat with nit. silv. “Vinegar & lemon juice may be used as a gargle” “If the ulcers are thick and leathery apply nit. sil.” “I have seen the brain affected and much spasmodic action subderangement pain in the head and all the symptoms of hydrocephalus with a bloating of the whole cellular membrane pulse frequent & extremely quick and all the marks of irritative actions For 3 or 4 years I have used tinct. dose in 4-5 & sat. tinct. canth. in 10 3 or 4 times a day giving also the tonic solution and keeping the bowels open” “It produces eruptions on the skin, heat dryness & soreness of the fauces febrile action & if continued 8 or 10 days I think it would be useful. I would try it were the disease severe and epidemic, whether I thought it contagious or not” 131 The sequel of scarlet fever is dropsy. In children especially an anasarca and sometimes an universal dropsy comes on after the disease has subsided. The first two cases which I met with were in the severe epidemic of 1803. I treated them according to the direction of the books, with bark & brandy opium & lost my patients Considering this as an affection of the absorbent and nervous system I treated the subsequent cases which fell upon my hands with tinct. cantharides & tinct. digitalis The digitalis allayed the morbid action of the exhalents & absorbents & the cantharides acted as a diuretic. “Give of each 2 or 6 drops every 3 or 4 hours It [opens] [illegible] in these cases the effect of irritative action hence the propriety of digitalis Hanneman proposes to prevent the recurrence of scarlet fever by the administration of moderate quantities of atropia belladonna an article which produces an eruption upon the skin, similar to the rash of scarlet fever. The influence of belladonna, upon this hypothesis is similar to that of vaccination in preventing small pox. The termination of the chain of actions in health in some diseases & if we say nature cures the disease then we may say when the tendency is [inevitably] to death that nature commits suicide. The latter is true of this disease Yet if this chain of morbid actions is broken up by a powerful impression the constitution will take on its ordinary action Scarce any disease is more curable when taken in season yet it would not be proper for a physician to say he could cure all cases then pretending infallibility I shd doubt whether Good had ever seen the progress of a single case. He says nothing about the first stage. The tendency of the disease is to destroy the patient not by infl. or irritation but by suffocation from a foreign body in the trachea The stages run into one another, and yet a phys. watching the progress would naturally divide it into three stages Always curable in the first stage unless complicated with some other disease rarely in the second almost never in the last yet I have known cases cured in the last stage The peculiar sound of the cough is alarming (in the first stage) even to those who have never before heard it Dr [Hesark] I have been told divides the disease as I have done into 3 stages and directs to give 2 grs. tart. ant. combined with ipecac. I shd give for the effect not according to the quantity. I put out 3 or 4 gr and give till the effect is produced rarely over 10 grs 132 Croup This disease has been called in America by the popular name of hives which is probably a corruption of heaves called rattles The name given it by Good is empresmia bronchitis. The most common scientific appellation has been cynanche trachealis or angina trachealis The persons attacked by croup are I have never [illegible] 3 and [illegible] almost exclusively children from 3 months to 12 years old # in one instance I have known it attack a person 60 years of age When it occurs in adults it succeeds other diseases I have known 2 or 3 cups of [illegible] “Croup sometimes though less frequently than most diseases, blends with other diseases as catarrh” Some have considered the disease as contagious, but though a few facts appear to favour the supposition, they are not numerous enough to establish a general law. Croup usually occurs in the winter and spring, when it is brough on by exposure to a cold and damp atmosphere. Children upon the sea coast are more subject than in the interior of the country, because exposed to more variable weather and more frequent [thaws] & notwithstanding the greater warmth of the climate on the seacoast For when the air is filled with vapour, the caloric of the body is conducted off with more rapidity than in a dry atmosphere, even if the temperature of the latter is colder. # It is principally confined to persons under 5 years of age though it sometimes attacks persons of all ages, and It is not precisely entonic or atonic & hence might be called specific in peculiar It is said that in croup the exhalent arteries are affected & in catarrh this [illegible] vessels Whether the different vessels are affected or not there is certainly a different action “I have thought croup might destroy life by coating the entire surface of the lungs with a mucous or membranous coat thus preventing the decarbonization of the blood” “I have never seen croup without more or less spasm; & probably in fatal cases it is always a spasmodic contraction that closes the passage to the lungs which is only diminished by the membrane. I never saw a case on the other hand of what is called spasmodic croup which did not if neglected put on the membranous & inflammatory form” A similar [membranific] inflammation exists in the duodenum 133 Croup is a specific disease of a peculiar kind and is never malignant. It comes on with all the symptoms of pyrexia and consist in an inflammatory affection of the mucous membrane of the larynx and trachea, which causes a remarkable shrill sound in breathing & a ringing cough by which those who have seen the complaint cannot fail to recognise it. The proximate cause is a peculiar inflammatory action of the system, determined to the exhalent vessels arteries of the trachea and bronchial vessels, where there is produced an exudation of coagulable lymph similar to that which forms on the membranes of closed cavities from inflammation & entirely different from secretion of the mucous glands whether healthy or unhealthy. This coagulable lymph which is thus exuded, always forms a membrane which lines the larynx and trachea, if the disease proceeds to a fatal termination, and causes death by suffocation. This appearance is always found in the tracheae of those who have died of the disease. The membranific inflammation distinguishes croup in its nature, from catarrh which is in all its varieties, an affection of the mucous glands Most diseases attack in the night “Diseases are cowards, they mostly attack in the night” Rush. “The peculiar ringing sound of croup is made in [expiration] that of hooping cough is inspiration” # As is the case when respiration is impeded by any foreign body there is a great deal of irritation # when the nose discharges [illegible] [illegible] it bronchial vessels secrete mucus and a new action takes place the patient will be apt to recover # The patient was subject to asthma and the croup was neglected until the latter stages finally died + “I have known this to happen only once In this case the friends were not alarmed because the child had been subject to catarrhal affections & the symptoms received no attention till the last stage” # Frequently appears to be [illegible] in the very commencement of the disease 134 This disease sometimes come on like a catarrh and continues two or three days without any alarming symptoms, until suddenly, & often in the night the peculiar symptoms of croup appear. At other times the first symptom of the disease is a severe paroxysm of suffocation attended with the hoarse & shrill ringing noise made during expiration like air through a broken tube & the peculiar ringing cough. The cough in its progress is attended with more or less of spasmodic action. # It is always dry; and when it becomes loose or when mucus is expectorated the disease is broken up and there is no further danger # It rarely continues so long as five days and is sometimes fatal in twenty four hours. Sometimes, though rarely the membrane of coagulated lymph is coughed up. I have met with but one case + In this the membrane was thrown up three times, at each subsequent time forming lower down than before # No disease resembles croup so much as suffocating catarrh yet there are obvious marks of discrimination The latter disease as I have seen it is not attended with much cough and the difficulty of respiration is not in paroxysms but constant & commence with the disease. The pulse is often quickened and when the system is prostrated may be low. # In suffocating catarrh the powers of life are to be raised by external irritants & excitement equalized by the inhalation of the vapor of [illegible] of warm water etc. “Mustard” “If pulse tense bleed” From the earliest of my practice I have been in the habit of dividing it into 3 stages [illegible] that they are perfectly distinct, but [illegible] person would naturally take this view Quiet between the [per.] apparently not much affected during the paroxysms Between the paroxysms pulse natural & eyes bright. You will know this disease in this stage only during the par. Parents in this place know the disease in this stage and send forth phys. In this first stage, the disease must be broken up by a powerful impression upon the system This may be done many ways Some are partial to a [illegible] & some to another “That which is best administered is best” A local effect upon the stomach will not answer I have relied more upon tart. ant. than any other & found it answer all reasonable expectations. I have preferred it to any other I have occasionally used other [illegible] I have found seneka better as an auxiliary than as a commanding [remedy] 135 Croup may be divided into three stages each of them requiring different treatment. 1st The forming stage 2nd The inflammatory stage & 3d The last or suffocating stage 1st In the forming stage, the cough is severe & hoarse & occurs in paroxysms of from five minutes to have an hour in interval. “There is little or no fever” The pulse is regular and small, & sometimes trembling. The patient is often chilly. In this stage the disease may with certainty be cured “I have not lost a patient & have not saved one in [illegible] when not called till the second paroxysm had commenced” In the treatment of this stage we must depend upon emetics. Large doses must be given moderate ones do no good. A dose should be administered sufficiently powerful to affect the whole system and call into action every muscle. We must be regulated not by the quantity but the effect for we must calculate to overcome the diseased action completely by the operator of our remedy. I have given three grains of tartar emetic to a child three months old, & kept up the action by the large doses of seneka repeated every half hour for six or eight hours Tartrate of antimony is the best emetic to commence with and may be given in a dose of from 3 to six grains of strong tart em. After its operation a constant nausea must be kept up by seneka or some similar article, for some time in order to prevent a return of the disease. The seneka excites a new action in the system. It may be given in decoction. Take zfs or zi of bruised seneka to half a pint of water, & boil away a quarter. Give a table spoonful for a It has so happened that with us the [serpentaria] has not answered so well as tart ant. It acts on the fauces perhaps more [illegible] than tart. ant. but does not affect the system act upon the skin & determines to the surface so well as tart. ant. We have not used it however except in the latter stages & perhaps have not given it a thorough trial Sanguinaria vide p. 212 has been used 50 perhaps a hundred years. Three generations of physicians in one locality have used it and relied on it in croup with as much success as upon other articles These mode of using it was in strong decoction without weight & give a table spoonful until the desired effect is produced till vomiting is excited or the disease is broken up There are however forms of the disease where it fails even in [illegible] “Much has been said of the good effects of calomel Give in large doses 20 – 30 [illegible] acting as an emetic it is serviceable but when catharsis is produced, the emetics would fall in with the catharsis. I never could in such a case make the strong impression on the system what I [illegible]” 136 does once in half an hour or as much as the stomach will bear. Seneka has been relied upon by some as a specific in croup, but it is inefficacious when inflammation is present, being a stimulant, and it is too slow in its operation for the first remedy. After giving it as the first article, other emetics seem to lose their influence; acting as cathartics; but after the violence of the disease has been broken up by other emetics, you may avail yourself of the nauseating & deobstruent effects of the seneka & effect a cure. Dr Rush preferred the turpeth mineral 2 to 6 grs as the first emetic. The physicians in Wallingford for 5 years make a strong decoction of sanguinaria, and give it until emesis or a cure is effected. This article may be used instead of seneka in the way above directed In connexion with these means the warm bath and fomentations may be used as adjuvants. Much has been said of the good effects of calomel in this disease You cannot rely upon calomel for the cure of the disease It is too slow in its operation. Never give calomel until you have broken the violence of the disease After emetics have operated and you have availed your self of the operation of seneca & sanguinaria and the disease still exists, give from 5 to 10 grs of calomel By this producing an orgasm in the system more powerful than the disease & continuing it until the latter be overcome, croup may be cured with more certainty than most other diseases. All diseases should be attended I know that there are some very respectable physicians who rely upon calomel For this purpose they give very large doses and produce [illegible] & [illegible] I should prefer it as an auxiliar. I have often used it but after the emetic or with the emetic or before the emetic A variety of other men [illegible] India tobacco which though not allied in botany are so in their operations The common tobacco is generally applied eternally to the pit of the stomach. Lobelia acrid & emetic loses some of its virtues by drying In its recent state 1 gr will often excite full vom. Indeed I have known vom. prod. by merely chewing the capsules & [illegible] without swallowing by the impression upon the mouth Dose of tinct. 20 drops to a t. sp. according to age Other acrid narcotics as veratrum & colchicum may be used In this forming stage bleeding is not indicative by the pulse, nor by state of the system and you will obstruct your efforts to excite a powerful effort of the system if you bleed 2nd stage In this acrid emetics are injurious seneka is too stimulating Sanguinaria had I have seen all the symptoms aggravated by bloodroot in [illegible] the high entonic stage # “If the disease is complicated with a similar affection of the stomach & duodenum give calomel & other cathartics” 137 to in the beginning & it is owing to the imperfection of or our art that every disease is not broken up in its first stages. When however croup supervenes upon other diseases, it is more dangerous. “Those who practice in the country rarely see the disease in the forming stage. I had one winter 20 cases of croup all in town recovered most of the in the country died” 2nd Country practitioners however seldom see this first stage which I have just been treating of when the tongue is not discoloured, the fauces have a natural appearance the pulse is unaffected respiration natural & ordinarily no inflammation about the tonsils. On the contrary they too generally arrive when the disease is in the second or inflammatory stage the disease has effected in which the bloodvessels the skin is hot and dry, the face flushed, the pulse tense & sometimes full the tongue furred, respiration between the paroxysms difficult tongue furred, respiration between the paroxysms difficult and the cough so severe as to threaten immediate death vide p. 213. In this stage we should immediately bleed from freely from a large orifice the arm or jugular vein freely, even until syncope is produced put the patient in the warm bath & let him also inhale the steam of warm water, and give calomel and other cathartics. # Never give emetics in this stage until after depletion by V.S. when we may give 4 grs. of tart. ant. in a table spoonful of warm water & apply epispastics to the throat” in the commencement apply a blister” I dread to be called in this stage of the disease, for it is the almost always fatal venesection sometimes succeeds but very seldom. I would not apply leeches cupping would be better & perhaps friction might be serviceable. Digitalis has been recommended, but In this stage inhale the vapour cover the child & nurse in a chair with a blanket In this stage cal. & cath. may be given In the first stages I have conserved it very unfortunate to find my patient under the operation of a cathartic It feels as if my hands were tied The excitement is of a different kind from what is wanted And emetics are apt to produce hyper cathartics Where the dis tends to the [illegible] the [illegible] a specific. This is known by the cough being less hoarse, by fever, by constipation fever more intestinal membrane will pass off from the duodenum I was formerly disposed to cure this form of the disease [illegible] & described it as such In the second stage epispastics over the whole chest also diaphoretics and tepid bath When the cough is milder and beginning to be loos after being principally broken up in the first stage give cal. in 2 or 3 gr doses once in 2 or 3 hours In the 2nd stage remedies have been given to obviate the fever & digitalis has been used with good effect It was used as a depressing agent It operates by its narcotic power however. here refrigerants are of little efficacy In what may be seen to be the last 138 I have not used it. It is at best but a doubtful remedy in inflammatory effections though calculate to remove more irritations. Sanguinaria diminished arterial action like digitalis and operates powerfully as an emetic. I have not succeeded with it in the last stages of croup & have not used it in the first. [?ronchotomy] has been proposed, but does not promise much benefit, as the disease is seated below the place for operating. “Dr Smith did not recommend it” After depletion and especially after the disease assumes a bilious form you may give powerful cathartics The pt. begins to thrown his head back death may happen any moment 3d IN the last or suffocating stage* you may give emetics of turpeth mineral sulphate of zinc or even corrosive sublimate to throw off the membrane. Something may depend upon changing the emetics & sulphate of zinc may be tried. The cold bath is said to have been successful in this stage, but the fact is not well authenticated. I have used calomel and the warm bath with advantage. Child of Mr Culver [last] in chronic stage “I regret that I have not tried affusion of cold water in the last stage. It is said to cause the membrane to be thrown off & to procure relief even in the very article of death” vide p. 182 *”In the last stage respiration is constantly laborious head thrown back pulse often irregular & intermittent sometimes strong” Chronic form “Sometimes though rarely the disease is only partially subdued I [illegible] on in a chronic form. Calomel vapour best tepid bath are the appropriate remedies” 139 Angina Laryngea Empresma Laryngitis of Good, q.v. for a definition & an account of the disease In this disease the symptoms differ somewhat from those of croup, though the cough is similar The disease is seated in the larynx glottis and fauces & the characteristic symptoms is swelling of the tonsils. The cough is spasmodic and is excited by taking food with drink in this respect also indistinguished from croup. The disease is more violent and rapid than croup, as the inflammation being seated in the narrow part about the glottis produce suffocation sooner. The respiration is more difficult than it croup particularly between the paroxysms This disease more commonly affect adults The first case that I saw was that of an old man in whom the disease was brought on by exposure to cold after a pneumonia From a relation of his symptoms I prescribed seneca which only exasperated the disease, so that when I saw the patient he was unable to speak or swallow. A small red spot appeared on the tonsils. venesection, epispastics, pediluvium, inhalation of vapor etc. were resorted to with no abatement of the symptoms. Venesection was performed a second time & as soon as the patient was able to swallow, 4 grs. of tartar emetic were administered. Some nausea and vomiting with considerable catharsis followed. The vesication “Angina laryngea is mor apt than croup to recur several nights in succession” “The slough were thick and leathery. Sloughing even under blisters. In one instance blisters did not heal in 4 mo. Lunar caustic applied to the tonsils & uvula & inflamed parts proved serviceable # “In one case of A. laryngea I gave sanguinaria It was too acrid and increased the cough etc. It might do good if we could avoid the local effect of its acrimony” 140 was extensively returned & the patient recovered. Much the same treatment is required as in croup but it should be more prompt and with earlier venesection. For the inflammatory stage comes on earlier and the disease runs a more rapid course Last year this diseases differed in its appearance from the former years It has often followed certain affections of the tonsils called black canker. The tonsils are inflamed in black canker and sometime covered with a leathery crust. This comes off and leaves an ulcer. If the inflammation extends to the larynx, symptoms of croup supervene Case of black canker. Two called in the last stage gave blood root with disadvantage # Still at this late period calomel and other cathartics in large doses produced free evacuations and the child recovered Cathartics appear to do better than emetics. In one case after giving cathartics I used the vapour bath and applied a large epispastic over the whole sternum. Though at so late a period the disease abated. A large slough however was produced by the blister which required three months to heal. The morbid action on the skin being similar to that of the tonsils Vie p. 187 Sometimes comes on with a sudden paroxysm of suffocation sometimes gradually “Distinguished in its commencement from croup by the quantity of mucus in the bronchial vessels” “in the case which I have attended, not much febrile action attended the disease” Proximate cause a morbid action of the lining membrane of the lungs accompanied with a viscid secretion of [mucus] By vomiting the disease may be relieved & apparently cured but may appear again in the course of an hour The quantity of mucus is greater than in any other catarrhal affection” 141 Catarrhal epidemic resembling croup Peculiar catarrhal affection resembling croup suffocating catarrh This disease is characterised by a severe hoarse cough, much resembling that of croup. The disease is distinguished in its commencement from croup by the excessive quantity of mucus in the bronchial vessels which causes the suffocation The disease resembles croup likewise in the mode of its attack which is sometimes sudden with symptoms of suffocation, and at other times gradual with paroxysms of coughing and intervals of perfect ease The turns of coughing are so violent in this disease as to produce a livid colour of the face. The extremities evident determination to the head are cold and the head is hot from the quantity of blood thrown into the vessel of the head by coughing. The evacuation from the bowels are healthy and among children with no disease which I am acquainted affect the bowels so little ass this. The proximate cause of the disease is a morbid secretion of mucus on the lining membrane of the lungs & trachaea with obstructed perspiration. The quantity of mucus thrown out by this membrane in this disease is astonishing After the disease is fully formed, great quantities of viscid mucus may be brought away by vomiting, to the great relief of the patient for a short time, and yet within an hour the patient will appear to be suffocating from the the quantity again collected in the bronchial vessels In the commencement of this disease, the indication is to break it up at once by a powerful emetic, of tart. ant. unless the system The principal indication is to break up the disease by a powerful action on the skin on the stomach the duodenum and the fauces It is best affected by tart. ant. which is more difficult in its action than [ipecac] though is very delicate constitutions ipecac may be practicable # prevent accumulation of [mucus] The bowels shd be evacuated not for the purpose of curing the disease but for the prevention of an accumulation of feces which would be irritating In all diseases of the lungs examine the state of the skin and particularly that of the lower extremities for perspiration upon the upper extremities [only] may be a part of the disease I have known the lives of several patients saved by the use of the vapour bath I formerly [illegible] and used [illegible] for transmitting vapour by transmitting air through boiling water It was old practice to apply cat-skins fowls split open (to the feet) etc. with the intention of communicating vitality 142 is too much weakened to bear this treatment. This is a general principle viz, if possible to break a disease in its commencement by means of a strong orgasm. Often the emetic is to be repeated, and it may ever be necessary to give four or five emetics 1 gr [illegible] tart. emet. each in the course of a day. After the disease is somewhat broken up, and epispastic applied upon the breast will assist much in allaying its violence # If the disease still continues or if when first called we find it fully formed and powerful emetics inadmissible the primary indication will be to open the pores of the skin and keep up a gentle perspiration, by small doses of antimonial wine to which may be added in all quantities of camphor by elix. [illegible] & in some cases tinct opii by fomentations and especially by the warm bath and the inhalation of vapour. To affect the latter object the child may be placed in the warm bath & a blanket thrown both over it and the nurse, so as to keep the child in an atmosphere of vapour. Long continued perspiration invariably relieves the symptoms. I have known an instance in which the skin of a sheep warm from the animals body was wrapped round the naked body of the child with beneficial effect. In small children when the stomach ceases to be excited by emetics the throat should be irritated by a feather or the finger, when we wish to produce vomiting For we must never rest satisfied with merely endeavoring to palliate the symptoms. In small children also the mucus should be wiped out of the mouth by the finger or a cloth This disease prevails most in the winter and spring months & does not occur every year. The first patient that I treated for the disease suffered from it a year. I gave mercurials & finally the silver pill (nit sil) 143 I was puzzled with the first cases of this disease which I met with. Some of them continued for weeks and months I was obliged to use perspiration, by warm bath to vapour bath emetics etc. I determined to break up the next cases in the commencement with tartar emetic repeated until full vomiting was produced walking my patients. This plan was more successful A s a general rule break up all diseases if you can “The complaint is epidemic or rather endemic. It has been mistaken for croup, but it differs As croup formerly occurred no mucus was raised in the earlier stages, and when there was an excretion of mucus we considered the disease cured But of late years the two complaints are somewhat blended. Mucus is thrown off sometimes without permanent relief” “There is often in this disease a disturbance of the brain and nervous system resembling epilepsy or chorea produced by the cough” A distinction was formerly made by some writers and some practitioners, between hooping cough and [chin] cough the latter being a spasmodic cough without the hoop. Such a distinction will not hold good there is no difference “Linneas and Rosenstein attributed it to an insect others to malaria” There had been a very severe winter & no one had left the island for months 144 Hooping Cough Pertussis Called also chincough This is a disease which generally attacks children yet occasionally, adults are the subjects. I have known persons of 60 years of age affected with it. As a general rule also it does not affect persons a second time. I have known about 20 or 30 exceptions & among them was the late president Dwight at 60 years Hooping cough generally appears as an epidemic. With respect to its origin there is considerable difficulty in making up an opinion. It is said to be contagious to arise from a specific contagion which affects a person but once. Dr [Dewers], however, says “We confess that we are inclined to believe that it depends upon causes of a more general and pervading influence that contagion.” Dr Cullen asserts that he has said a disease which though evidently arising from chincough contagion never put on any other form than that of common catarrh. In the tenth volume of the medical commentaries DR Willey gives an account of the breaking out of the disease on Block Island under such circumstances that it would seem that it could not have originated from contagion. When the disease prevails many become effected where every precaution is taken” When the disease has been extensively prevalent I have not been particular about keeping patients apart, perhaps however it is best for prudence’ sake to consider the disease as contagious and to treat it as such. One fact I have noticed that in particular seasons may have the disease who have had it before.” Some suppose that it is contagious only in the first stage others in the second “Some think it caused by malaria or animalcular” “The stricture may be overcome by not attempting to inspire, but to expire till the lungs are emptied the pat. can then inspire without difficulty I have known persons subject to this kind of hooping without cough Adults are sometimes attacked in the night with paroxysms of suffocation they start from bed when the recover their breath there is hooping but no cough, at least at first The more they struggle to catch breath the greater the difficulty there seems to be a spasm of the glottis Let them make no effort to inspire but expire the little air remaining in the lungs & they will bye relieved at once. The disease is liable to recur bathe the feet at night give paregoric wine whey diluents The disease is not described 145 Some suppose this disease a peculiar inflammation of the mucous membrane of the trachea and lungs, others that it arises in the bowels This disease often commences with the symptoms of ordinary catarrh & continues without alteration for some days. Sometimes the peculiar mark which gives this cough the appellation of hooping & distinguishes this disease from every other does not appear until the 3d or 4th week It is impossible however to distinguish the disease until this peculiar hooping makes its appearance. When the disease is prevalent it will be safe to treat every severe case of catarrh among children as one of this disease The phenomena peculiar to this disease may be the described. Several frequent expirations are made in succession by spasmodic coughing, and a full inspiration is then necessary to restore air to the lungs. The air as it passes rapidly into the lungs produces a loud sound called whooping The sound however is made more by the structure of the passage than by the rapidity with which the air is drawn into the lungs I have known persons subject to this kind of whooping, without having a cough caused by a spasm of the muscles of the trachea larynx? to which adults are sometimes subject. (Goods laryngismus?) A similar sound is also made in croup, when the air is expired after the passage becomes constricted The patient is aware of the coming on of a paroxysm of coughing by an unpleasant sensation in the throat, & The cough is violent in proportion to the shortness of the paroxysm 146 it is common for children support themselves during its continuance by changing to a chair or other support near them. During the paroxysm the blood is returned with such violence to the head as to produce a livid colour of the face & often in bleeding at the nose. Very violent paroxysm sometimes in young children terminate in convulsions or death The paroxysms continue until a quantity of mucus is thrown up from the lungs or the contents of the stomach are evacuated by vomiting They are short in proportion to the facility with which the mucus is brought up or rather in proportion to the rapidity with which it is secreted It is the secretion of mucus, not its removal which gives relief to the irritation of the lungs Many suppose that this mucus which is generally in considerable quantity is the cause of the paroxysm of coughing instead of the effect of it. The peculiar irritation of membrane in a paroxysm of coughing produces a secretion of [illegible], and when a sufficient quantity has been secreted it is coughed up like the secretion of tears from an irritated eye and the paroxysm is relieved “The mucus sheaths the part & the ceases” The disease continues from one to six months It is often kept up by habit. The cough is usually more violent by night than by day. Violent cases are often attended with considerable fever and in the worst cases respiration is laborious between the fits of coughing. The disease may terminate by apoplexy or suffocation or by ulceration of the lungs and hectic & sometimes by permanent visceral obstruction “or apoplexy or suffocation” Whooping cough is not dangerous to adults and I have never known a child over two years of age die with it. It is most dangerous to infants and the younger the It is usually dangerous to children within the mouth It is apt to wear out very young children especially if they are of a scrofulous tendency It is frequently accompanied with a morbid sensibility and irritability of mind and hence in the latter stages a change of air and of place is salutary as in cholera infantum The same despondency of mind takes place as in chol. inf. q.v. The disease is a fever spending itself upon the lungs and trachea, and affecting also the glandular system Some phys. think this dis. like common catarrh, is always inflammatory in its commencement, and requires antiphlogistic treatment. But we know that pneumonia may be highly typhoid & require treatment opposite to [enteric] pneumonia. If infl. of the lungs exists the antiphlogistic treatment shd be adopted in its fullest extent I have seen antimony as efficacious in this dis as in pneumonia. In general perhaps mild antiphlogistic diet & treatment will be proper. In some cases I have thought the veins lost their power, and in such cases the blood [illegible] has been prescribed & with advantage It is a catarrhal fever at first and to be treated as such 147 child the greater danger in children under the age two years The anger, to be apprehended from the disease will also depend upon the debility of the child when attacked. The cough may be violent and attended with frequent vomiting yet of the patient’s appetite be good there will not be much danger to be apprehended. A moderate hemorrhage from the nose is often salutary Treatment. If the disease is mild and the constitution good little need be done with the way of treatment. But if inflammatory symptoms supervene with a tendency to pneumonia the antiphlogistic treatment must be adopted. Bleeding will often be advisable. A small quantity of blood taken from the arm proves serviceable. In general greater effects may be expected from the application of a few leeches to the breast or neck than from bleeding at the arm but when decided symptoms of pneumonia appear, & the blood seems to be transmitted with difficulty through the lungs. I would recommend venesection. In this case also the bloodroot will be the best article for internal administration In most cases the disease comes on like a catarrh, and should be treated as such, with mild antiphlogistic regiment [illegible] important part of the antiphlogistic treatment of this disease is the keeping the bowels open. Costiveness frequently attends the disease & should be carefully avoided. In general it is better to obviate this symptom by diet as far as it can be done Begin with antimony in small doses 1l or 2 drops ant wine & in [illegible] For very delicate children however it may be better to give ipecac Almost all the writers recommend vomiting [Best] 148 rather than by medicine. The best cathartics for the indication are those which excite the secretions of the stomach and liver. Sometimes the disease has a tendency to produce congestion of the liver and obstruction of the mesenteric glands and in that case also mild mercurials should be given and their use continued as long as any symptoms of congestion exist. All the medical writers on this disease recommended vomiting in the first stage Tart. ant. is in ordinary cases the best emetic. Sometimes for a child from two to six months old two drops of antimonial wine will be an emetic dose while for another of the same age 20 or 3o drops may be required. In affections of the lungs children will bear antimony better than in those of the stomach and duodenum. In some constitutions antimonial emetics produce (in this disease) a sort of spasmodic stricture other emetics also may produce this effect a symptom which must be relieved by diluents and opium In general antimony in small doses may be given to children of any age, either by itself or combined with a small quantity of paregoric or any other mild preparations of opium. Given in this way it removes febrile action and congestion of the lungs, and determines to the surface When the disease has proceeded with You may see the fontanelles swell in such cases. I recollect a child in the whooping cough going into the country I told the parents not to suffer the child to be vomited. A physician in the country said the child must be vomited of course all the books directed it in whooping cough He vomited the child. It went into convulsions and died # Here insert the recipe for hire syrup or compd sys. of squills p. 150 I have known the lives of some patients saved by this antimony internally had lost its power produced no effect 149 violence for some time and there is much determination of blood to the head, threatening convulsions or apoplexy from distention of the blood vessels, or when the patient has become debilitated vomiting by emetics should not be practises or but cautiously. When the system and particularly the stomach has become debilitated. Ipecac is preferable to antimony, given in emetic doses, or in small quantities as an alterative diaphoretic and antispasmodic. And in the latter stages likewise on account of the debility, sulph. tinc. is a good emetic using 5 or 6 grs. with as much of ipecac If there is not much febrile heat, and there is much viscid mucus in the stomach and lungs, and emetic of squills is often serviceable # particularly I [illegible] phlegmatic temperaments syrup of squills vinegar of [illegible] In this disease if there is danger of convulsions from vomiting, blood root and similar articles should be given. The hive syrup or compd tinct. of squills may be used In children under three 6 months, whooping cough may be much relieved (respiration being promoted) by vesication on the breast. A blistering plaster may be applied but I have more generally used the following. Rx common or mild tinct. canth zi targ. ant zi Dissolve the ant. in the tinct. & apply a linen cloth with the mixture till [illegible] or partial vesication is produce & then dress with simple cerate In this way we have the vesicating & irritating qualities combined. This external use of tart. em. was recommended 20 years ago, in the Lon. med. & ph. Journ. This disease may be cured in its first stage but it ordinarily runs a regular course & the treatment is generally palliative brown mixture You will perceive that this is a strong decoction of seneka and squills, with a large proportion of tart ant. shd be given cautiously 4 to 30 drops Narcotics have been strongly recommended e.g. atropa belladonna & hydrogen of the former for 2 gr of the leaves in powder Alibert recommends the fresh bruised root 150 A popular remedy in whooping cough in Godfrey’s cordial, made of molasses and water with a little laudanum and oil of [illegible] “Hive syrup” (or compd syr [illegible]) is made as follows Rx bruised seneka root & squills zz z8 water lb 8 boil and evaporate one half strain and add honey 4 pts boil to lb 6 Add tart. ant. gr.i to every ounce Give for an emetic 8 or 10 20 drops to a child 4 mo. old & repeat the dose every 15 or 20 minutes until vomiting is produced The “brown mixture” is as follows elix. pareg. zi; ant. wine zfs; ext. glyc ziii pul. gum ar. zii wat. zvi trit. & boil dose from ½ teaspoonful to tablespoonful This has been very extensively used This disease has been prescribed for more empirically than most others; a fact which proves the difficulty of curing it It is a popular notion that it must “run its course” & under the influence of this many parents object to its being prescribed for. Undoubtedly this like every other disease must “run its course,” if it is not cured; but this is no reason why the cure should not be attempted. Ammoniae asafoetida (especially if the cough is kept up from habit) 1st antispasmodics 2nd tonics # An emetic is occasionally administered with advantage “I have prepared this from seneca oil also from gun copal” 151 2nd In the second or chronic stage tonics & antispasmodics are indicated. Sulph. of copper or of zinc tinct canth. cinchona, arsenical solution etc. may be required to rouse and support the system & as antispasmodic tinct. asafoet. petroleum Artificial musk etc. and also the narcotics, as hyoscyamus, conium, stramonium, belladona arnica, opium etc. When the cough is kept up by habit, # asafoet. is often administered to children with advantage. It may be given in tinct. or decoct. & if it cannot be given by the mouth it may be thrown up in an enema, using 10, 20, or 30 drops of the tinct. It is a valuable [illegible] the taste is less unpleasant than the [illegible] Artificial musk or oxygenated oil of amber was first introduced by Prof Hufeland of Jena as a specific for whooping cough and has since been found very useful in other spasmodic diseases vid. Lon. M of ph. J. vol. 1: p.181 van Swieten’s comm. etc. Rx nit. ac ziiifs cl. succini zi. And the acid gradually, ina temperature of 100 [degrees] or in the sun. Prof. Hufeland triturated x or xii grs. in a mortar with a few almonds & diluted with z 5 or 6 of water & gave a teaspoonful every 2 hours to a child a year old. This preparation was very celebrated and very effectual, for a time, but afterwards fail was thought to be ill prepared. The truth was the diathesis had changed. Probably it will be as affectual at [illegible] time I have given the above article in tinct. Rx zii of the oxyg. [illegible] [illegible] lbfs alcohol dose 10 to 12 20 gtts It is much more soluble in ether. I frequently dissolve zi of oxygenated amb. in zi of ether dose 1 to 2 drops on sugar 152 It may be prepared indeed of any strength, to suit the convenience of the physician. Probably gum copal oxygenated would answer the same purpose as amber as there is every reason to suppose that the two are essentially the same amber being gum copal mineralised Case of a vein of olibanum or Frankincense found in S. America. Opium is not indicated in this disease except when it is qualified and its action determined to the skin by antimony ipecac or camphor. Hyoscyamus is better than opium for in the cough it produces no constipation and the tincture is very pleasant. I have not however used it in this disease. Conium has been recommended by writers of the first respectability, but later authors do not speak of it with much confidence. It deserves a trial when other things fail. Alibert recommends atropa belladonna 1/6 gr. of the root or leaves powdered & given in milk I have used I have more confidence however stramonium in the [illegible] & think it preferable most of the narcotics to any other narcotic It is peculiarly calculated to remove spasmodic action depending upon irritability of the system or kept up by habit From the relief obtained by its use in asthma I was led to employ it in this disease and from those cases in which I have tried it I am of opinion that it is a very valuable remedy in it The ripe seeds of the stramonium are best the full dose of these for adults is gr. ii for a child 1/10 gr. or more according to the age Mercurials occasionally blue pill rhub & ipecac enough to keep up a gentle excitement in the bowels Not unpleasant to the taste An old [illegible] Chalmers ([illegible] of silver) recommends sulph. cop. & tinct canth in wh. cough # [ago] more used than any other Lately the ox. bis. has taken its place dose the same used for irritating cough & irrit. of stomach 153 Carb. potash is a good antispasmodic used externally and internally. It is not only antacid & antispasmodic but it appears to me to produce a peculiar excitement upon the stomach and aesophagus, which makes the more susceptible to the impression of other articles. Pearlash zfs & water z8 with cochineal enough to colour the solution has been considered relied on by some physicians a specific. The cochineal merely colours the solution. is an article from which I never could perceive any medicinal effects when used alone. I have tried the experiment & could perceive no medicinal effect from it Tonics. I have given the sulphate of zinc more than any other tonic in this disease, and have experienced the greatest benefit. Sulph. tinc given by itself, sometimes produces spasmodic action, the effect I attribute to its being used in substance & hence I always give it in the form of Moseley’s tonic solution. This preparation is both conic and antispasmodic is easily taken and retained on the stomach of very small children Sulph. copper possesses properties similar to those of sulphate of zinc. It is administered in the low stage of whooping cough. In this place the preparation of it called compd tinct vitr has been used according to the recipe in the 10th vol. Duncan’s Commentaries in doses of 3 to 30 drops according to the age of the patient The oxide (or flowers) of zinc & also bismuth formerly much used in spasmodic cough 30 grs have been occasionally used 1 to 3 grs 1 to 10 to an adult The Peruvian bark is a good remedy in the last stages. The only objection to it lies on the difficulty It sometimes happens that the physician is not called in until the latter stages. As one resort we may have recourse to irritate along the spine It is an opinion very extensively prevalent to that it is of no consequence what kind of food a child takes when he has the whooping cough But great attention shd be given Removal from sea side to country and [illegible] country to sea side either is beneficial 154 of administering to small children, a quantity sufficient to produce any considerable effect. This difficulty may now more be overcome by using sulph. quinine ¼ gr to 1 gr Dr Chalmers of South Carolina recommends a combustion of bark, sulphate of copper and cantharides Tinct. cantharides has been long since recommended for whooping cough. It is useful when the system requires an inflammatory diathesis to be produced. Its action on the stomach is probably similar to that which it has in cases of gleet and leucorrhoea the stomach being in a relaxed state & requiring to be excited to a healthy inflammatory action Irritants, as oil of capsicum canth. [illegible] or ol. orig. or vol. lin. rubbed along the spine have been used in the latter stages. They should be tried when you have reason to suspect that the spinal marrow or the nerves proceeding from it are affected. Attention should be paid to the diet of children in the whooping cough avoiding potatoes, oily foods etc. Change of scene & change of air especially by riding should be resorted to in bad cases, to tranquillise the patient & furnish mental excitement. Sometimes the little sufferers will be excessively irritable constantly worrying and teasing until this is done requesting first one thing & the other to be done. It is the worst of such cases, medicine does little good, even the irritation produced by administering it may counteract its beneficial effects. violent palpitation throbbing of the heart a soft flowing pulse and a jarring feel of the pulse under the finger ([illegible]) (The French call an enlarged heart hypertrophy I object to the [name]) For this I have given nit. sil. 1 or 2? gr. (in the chronic stage of [illegible]) Digitalis & also [languinaria] (tinct. 2 or 3 gtts.) This article is dangerous for children because it accumulates in the system Lead has been recommended I have been doubtful with respect to its propriety in affection of the lungs etc. # Pneumonia typhoides 1815 the system seeming to lose the power of [illegible] the blood and the bloodroot was given to promote venous absorption The digitalis might probably be given in such cases but is not as well adapted. I used the blood root and found as much benefit as could or [expected] from any article 155 If the patient having the whooping cough happen to be teething the treatment recommended for dentition should be employed The patients are very liable to have an inflammation of the lungs from taking cold in any stage of the disease & in such cases the remedies for pneumonia should be administered, such as antimony bleeding epispastics, bath etc. The disease I think sometimes determines to the head & produce a relaxation of the sinuses & [illegible] likewise produces a relaxation of the ventricles of the heart the immediate cause being the violence of the cough In such cases I have used lead, but not in sufficient quantities to enable me to recommend it Iodine has been recommended 2 or 3 doses 3 times a day Nit. sil. languinaria & digitalis When in the progress of the disease the circulation becomes much affected the pulse frequent, soft, flowing with occasional intermission respiration high frequent and laborious, with a bloated and sometimes analogous to # a livid countenance, the blood root has done more than any other remedy not failing in any instance to give relief & palliate sympt & in some cases the relief has been permanent. I gave the bloodroot repeatedly, the last spring, 1815 to my patients in the whooping cough. To a child a year old 5 to 10 or 20 grs of the dried root, according to the urgency of the case, infused in 6 or 8 teaspoonful of boiling water. Give a teaspoonful every hour, until vomiting is produced or the patient relieved. Children Sometimes the dis. will be very mild and yet leave the system in such a state that a slight subsequent disease will carry off the patient e.g. in 1815 the dysentery attacking children would often be very slight and yet would carry off every one who had had the whoop. c. in the spring. The attack would be mild and insignificant of dysentery and yet the pat. would go into a [illegible] very speedily like cholera Elaterium has been recommended I shd be cautious in trying it except in very vigorous children I can speak with confidence of arsenic. Excepting occasionally prussic ac. I know of no remedy which so completely cures the wh. cough except prussic acid in some cases. Case child 2 gtts night & a [illegible] in a weak countenance pale, eyes dull face bloated muscular strength weak muscles soft & flabby Parents much [illegible] cough gone recovered colour & strength upon bark I have known several such cases and have known no ultimate injury result from this practice Yet parents are afraid 156 who had the whooping cough that spring were very liable to be carried off by the dysentery of the following summer none died in 1815 of the disease but many in consequence of it, with hydrocephalus and dysentery Prussic acid dose 1/3 of a drop to begin with and arsenic occasionally cut this disease entirely short; and these are the only articles which I have known do so, without leaving a vestige of the disease behind. The former is a dangerous article to use, from its want of uniformity and strength Fowler’s solution of arsenic gtt more [illegible] is safe but does not answer so well in the first stages. If it makes the patient feeble livid bloated & with swollen lips etc. it must be stopped & perhaps bark administered. It has cured the cough in the second stage. Dose 1 drop 1 or 2 drops twice a day. Sometimes is only palliates Case. June 1815. A child of Capt. Totten’s a boy of 5 yrs of age rather full habit had been affected with the cough for a fortnight before I saw him I found his pulse very frequent soft convulsive & with intermissions face swollen and livid, circulation much increased on slight palpitative [illegible] motion of the body in the symptoms aggravated to an alarming degree by a paroxysm of coughing. Previous t the disease a remarkably even tempered and pleasant child he was not on the contrary very irritable. Trifles irritated his mind, and when irritated, all the symptoms of his disease were aggravated. He took an emetic of ipecac, with The sequels of this disease are numerous Sometimes the heart is affected as above and continues so for years. Sometimes the glandular system is affection. Sometimes the lungs. There is a lady in Philadelphia who had (under my care) suppuration of the lungs whoop. cough now healthy hence never despair The stomach and abd. visc. are sometimes affected in a chronic way requiring dandelion mercurials hop [illegible] etc. It is very tedious to attend children in the chronic stage an account of the excessive irritability When bath recommended Cold bath doubtful. I have known patients killed by being brought from the country and plunged in the sea bath “Good speaks highly of rhus [illegible]. It is given to produce a distinct action on the system which shall overcome the diseased action. It determines powerfully to the surface and has a powerful exciting effect on the blood vessels while it does not produce a determination to the brain. I should not recommend this article and it is so uncertain in its effect. On one person it will have no effect at all, when in another it will cause swelling of the eyes, blindness, fever, & great irritation 157 but inconsiderable & temporary relief. He was directed to take the bloodroot every hour, as much as the stomach In relieved the violent symptoms would bear. It was continued for two or three days, and the palpitation of the heart was much abated, the circulation was less irritated, & the livid colour of the face was gone still did not cure When costive he was benefitted by full doses of cathartics. because the system was [illegible] deranged heart lungs etc. I considered the case a fatal one and expressed that opinion to the parents. The cough and other symptoms continued though in a less violent degree disease chronic an epispastic was applied to the chest very irritating (changed clothes often in the day [child] run upon various subjects) Patients strength began to fail and tonics were given white vitriol bark cantharides Finally the patient refused to take any medicine and was left to his own appetite called obstinately for it took cake for food for several days then baked pears then [illegible] Afterwards recovered but was unable to run “for some years” without a palpitation If this disease should again prevail I think I should atropa belladonna as a prophylactic. As the disease continues the stomach may become very much debilitation and require compd powd of [contragerva] cat carilla etc. etc. “Ledus palustra are narcotic” It is not certain that the dis. did not exist before It may have existed before but no general account given of it. It may have been known in diff. places by diff. varies and it [illegible] have been known than the diff names meant the same disease Diseases are not apt to appear suddenly. Still at this period, there [illegible] cause operating for the increase of the dis. Belly usually large and limbs small Joints unusually large Often morbid cravings of appetite Yet the same causes operating in a higher degree produce cretinism There is no difficulty in recognizing the disease You will be struck at first sight with the large size of the head the blue [veins] of the forehead paleness of countenance as you cast your eyes down you will notice the large joints 158 Ricketts This disease according to Underwood was first noticed in England in the year 1628. It is said to have immediately succeeded the increase of manufactures, when people left the villages to settle in large towns, where they wanted exercise and a pure atmosphere Children are rarely attacked with this disease earlier than the sixth month and not usually until after that period. The symptoms are soft flesh muscles & cell. sub. relaxed general relaxation of the system paleness of the countenance unless the face is flushed with fever, which when it exists is of the hectic kind a fever of irritation pulse, usually quick and feeble, tumefaction of the abdomen appetite and digestion bad tendency to acidity veins of the head [illegible] and blue the sutures of the head not firmly closed head large fontanells unusually open joints large in bad cases all the bones of the system enlarged & softened One effect of the disease is that the teeth are cut later than usual. Ricketty children are usually precocious in intellect. Their mental faculties are developped more early but are not capable however of so much improvement, as those of others. Evolution of the mental faculties does not proceed with the tardy progress of the assimilating function The child learns to [illegible] very early and exhibits an acuteness of intellect beyond his years with the exception however of those cases so severe as to have a tendency to cretinism It is a common saying that very forward children are not likely to live long and the precocity of scrofulous & rickety children may have contributed much to the production of this impression. Too much heat may produce an indirect debility Undoubtedly aff. the brain & nervous system Give mercurials occasionally Do not produce salivation and do debilitate by mercury Frictions are very efficacious exciting the skin The reasons why friction are not more successful is that they are not perservered [illegible] the al. can. etc. The cold bath is the only strengthening remedy which acts suddenly No effect can be produced by any medicine equal to the astonishing effect of exercise & amusement in many cases of chronic aff. of stomach & bowel. 159 The causes of this disease as in some instances a predisposition transmitted from debilitated parents sometimes a syphilitic taint of the parents In others bad nursing the children being kept wet and dirty and confined in close & damp apartments or if the child has been carefully fed and kept clean debility produced by confined air too great warmth, too great variety of food and as some think too much saccharine matter in its diet. Inanition may be a cause. The disease prevails among the Alps and is perhaps there caused by the combined influence of cold and moisture This is a disease of debility nearly allied to scrofula & cretinism affecting the viscera of the abdomen generally, the lymphatics and the [isseous] system. The chylopoietic viscera are probably first and afterwards the mesenteric & lymphatic glands generally the indications are to give tone to the system and excite healthy secretions The diet should be dry and nutritious and such as is not only easy of digestion but rather stimulating and the bowels kept open by cathartics which act on the secretions. A dose of calomel with a little ipecac will be useful. The cold bath should be used every day Take the child out of bed in themorning bathe & return. If the Cold bath of salt water is [illegible] tonic patient be very feeble it should be begun with at of a temperature of about 80 [degrees] and gradually used colder The child bath is equal to all other remedies It is more tonic if made of salt water As a substitute for exercise, frictions will be very useful But exercise in the open air should be like whenever the weather is good in a carriage or on horseback and exercise should be so managed as to afford amusement and mental The [guephalin] [polyapt] & also the gr. marg. (which is less odorous) are also used Their agreeable odor if there is no other advantage will prove grateful stimulus & promote healthy secretions Take the child out of bed and plunge him in water (about 70 at first) and replace him in bed Yet in exhaustion of fever the cold bath gives a shock from which the system will not react but yet in the debility the cold bath is highly beneficial whether we can explain it or not. It may be necessary to vary the tonic And it is desirable to have a variety of tonics to [chorea] from also carb iron & tinct. carb. iron ac. fer. alkaline solut The sulph. zinc is not inferior to iron and is not subject to the inconveniences of iron not producing inconveniences Mosely’s sol. The compd tinct vitr. although apparently [illegible] is yet certain in operation and has been long used in this vicinity A tinct. of potash is thought very useful to rub the body with. It is a popular remedy & has sustained its reputation in this neighborhood for many years Lime water made of caustic lime is more tonic than the carbonate That made of shells is thought better being pleasanter than that made for stores probably not as pure but containing muriate of lime. Be careful to see that the shells are thoroughly burnt so as to fall in powder when 160 stimulus by the sight of scenery vegetations, flowers etrc. The patient may even be benefitted by being carried in the arms into the garden and amused in this manner. It must not be forgotten that this cheerful excitement has a powerful effect on the secretions. Feather beds should be prohibited. They are too enervating, and hard ones should be used in their stead. Beds made of the sweet fern (comptonia [asph??folia]) are popular & do very well. They not only from their hardness check the profuse perspiration of the hectic diathesis, but correct the acid smell of the sweat which is very common. IN general heat should be avoided as too relaxing I have rarely failed of curing the disease by the cold bath as the principal remedy, using tonics however as occasion may require. The tonics which we may use are sulphates Phosp. & mur [illegible] 3-10 grs of zinc & of iron muriate of iron martial flowers of iron etc. and the plan has been tried of applying finely powdered bark eternally in a quilted jacket of flannel. It is difficult to give bark in substance to small children. Astringents may be indicated & there is often a degree of acidity so great as to indicate a free use of absorbents The alkalies as pearlash may be beneficial internally & frictions with pearlash & water zfs to a pint may be recommended. Of late iodine has been given in doses of from 2 to 4 drops of the alcoholic tincture 3 or 4 times a day, given mucilage or other convenient vehicle. This article when persevered in has cured a great many cases. It should be [given] at first in small doses & the quantity be gradually increased or a disgust towards it may be created Phosphate of [illegible] was popular Forgetting that the deficiency of [osseous] matter may be defect in the action of the secretions Though the theory was wrong yet the practice was found beneficial absorbents Give a solution of the acid of about the strength of lemonade The phosporus is preferred to the phosphoric quenches in the water you will then have, not as is too commonly the case merely smoky water but lime water of full strength These preparations are called tonics by Good called stimulants (too loose as use of the word) Long before I had any explanation in [illegible] I thought I observed that these articles created a susceptibility to the operation of tonics apparently as generating excitability 161 It has been supposed that the proximate cause of this disease is a deficiency of phosphate of lime with bones but this is an effect, caused by want of action as those vessels which secrete this substance. The proximate cause, as it is called, is in this case the disease itself. In consequence of this notion burnt bones have been much prescribed. They are probably useful not as supplying the matter of bone but as an absorbent & perhaps as a tonic Acids especially the phosphoric have been given. Phosphate of lime has been used with benefit muriate of [illegible] and barytes were formerly much prescribed. The worst cases are those of children born of syphilitic parents for these tonics mercurials and the cold bath will also be the treatment. I give them corr. subl. 1/30 gr with no injurious effect Nearly allied to ricketts and often as sequel of it ricketts often running into it Sometimes appears with ricketts sometimes afterward Ricketts occur with the year. Scrofula occurs later. Ricketts children are more generally of a scrofulous temperament The tendency may exist in the parents and yet be developed only in the children from the causes of bad food [illegible] pain etc. These swellings may continue in children of 5 or 6 [illegible] or within the year with little or no change but increasing of size in spite of poultices filling the whole neck I have found poultices apparently injurious promoting the relaxation but blisters would stimulate and bring on a suppuration. The pus will not be healthy but curdy and whey like The edges will be ragged, not unite readily, and will leave a bad scar. Scrofula, ulcers are said to be distinguished by a smooth overlapping margin. the disease may continue for months and years with little or no change of it does not attack a part essential to life as the lungs, producing tubercular consumption attacking the liver producing a peculiar atonic infl. I have seen cases of scrofula that were [entonic] They were injured by tonics and benefitted by cal. and ant. They would have borne bleeding 162 Scrofula This is a disease of the lymphatics and affects persons of a peculiar temperament this temperament is characterized by a fair, thin, translucent skin, light hair, blue eyes, sometimes black hair and eyes delicate fullness of lips & nostrils usually texture of skin and cellular substance general laxity of muscular fibre usually delicate organization mental faculties developed early on in ricketts. Person who have been affected with ricketts in infancy are after affected with scrofula in after life. This peculiarity of constitution, when a morbid action is superadded, gives rise to the following symptoms First small swellings appear about the neck, slow in their progress & with an imperfect suppuration. Small holes form in the swelling and discharge a subpurulent, watery and flocculent fluid. These scrofulus ulcers when fully formed are distinguished by smooth spongy and overlapping margins & by very lax granulations. The disease forms tubercles upon the lungs, liver kidnies & ovaria & causes a great enlargement of the mesenteric glands This morbid condition and action may be transmitted from parents to children. It prevails especially in cold and variable climates exists most in large manufacturing towns where it is caused by bad food and air, want of cleanliness all of them debilitating causes It is sometimes also in persons predisposed, a sequel of other diseases particularly of small pox, hooping cough & measles Treatment. more may be accomplished in the treatment of scrofula by diet, exercise, sea air etc. than by remedies. Scrofulous swellings should be treated by Avoid cold vegetables & watery diet give animal food articles containing nitrogen as infants are said to abound more in albumen and adults to be [illegible] “Iron zinc copper silver tonics & antispas. are useful” “Conium 2, 3, 4 grs with carb. fer. 10-20 grs” # “I have used with advantage mur. lime 3-4 drops increased to a tablespoonful & also mur. [illegible] 3-30 drops given in milk & water or in coffee. They are tonic & act on the lymph. & gland. syst.” Articles containing [illegible] In [anthelmint???] vesicular [illegible] F. idealis ([illegible]) (sea cabbage) has been given for worms and some families learn their children to cut it A mucilage may be made F [vesiculosis] [illegible] which with bran has constituted a popular poultice for scrofulous tumours When there is loss of tone & an ill conditioned discharge cantharides with opium is a valuable excitant Never continue any remedy after it debilitates by exciting disgust and nausea Mercurial plaister of the shops (gum ammoniac & blue ointment equal parts) has been much used especially for scrof. [swell.] of the joints In these [illegible] become extensively effective and become spongy A man at the westward was very celebrated for curing scrofula. He used wild violets but was not particular as to which species he used 163 blistering van Heuvel’s child a round of remedies had been tried [illegible] Occasional purging with calomel and rhubarb and ipecac in a pill will be useful Preparation of iron, carbonate of iron with conium etc. muriate of [illegible] 3 drops or 6 and barytes in [illegible] you give a teaspoonful iodine scrophularia mar. [Cistus] Canadensis uva ursi Mr Daggett Havanna Dublin Eliza Collis Vide p. 209 Iron no prep. perhaps are better than myrrh mixture or Jenkins’ pills (carb. per. [illegible] camph.) “Bark & quinine” Different preparations of [illegible] & barytes # Now superseded by iodine. I have seen more powerful affects produced by 4 dr. tinct. iod. persevered in a long “5 to 20 gtts within the year 2-3 gtts ter in die” Various vegetable articles I think very highly Rock rose or Cistus Can. (Helia [illegible] [pity] it is changed) Some years since a person went to Long Island to be cured of scrofula to a family famous for curing scrofula returned much benefitted should his remedies they [illegible] [illegible] & [illegible] always used than afterwards, when [illegible] [illegible] from Havan. neck filled up cured by [illegible] had been salivated W. I. without benefit Eliza Collis scrofulous cough much [illegible] cured by [cistis] vide p. 209. Scroph. maril. has been popular has been much used by empirics I have seen it sold at a great price brought from the west a very common plant It has been celebrated for accelerating parturition probably with out foundation The article has probably little or no power. Yet it is advantageous to know such articles in order to [illegible] [illegible] Two entirely different diseases but are classed together and may be treated together “H. externus is correctly named hydrocephalus” “No fever ordinarily attends. The disease consists in loss of town in the absorbents” Of late iodine has been recommended [illegible] two years since I was called to a patient with had enormously distended [illegible] [upon] gr. cal. & 2 drops tinct. iod. [illegible] recovered Tinct. canth. Face pale and bloated child sleepy and [illegible] I know one child who recovered, but at at the ages of 5 or 6 years died of H. internus. If the patient recovers he is more liable to the acute disease afterwards. Puncturing the membrane has been tried with success, and the application of bandages then supporting the child. It is said that puncturing of the pressure has [illegible] 164 Hydrocephalus Divided into two species externus and internus In H. externus the water is formed between the membranes of the brain (between the brain and its membranes?) In H. internus it is in the ventricles of the brain H. externus make its appearance at birth and is usually born with the child. # In its ordinary form it is fatal (It is almost always fatal when it makes its appearance immediately after birth and always so if born with the child) Stimulating and discutient applications to the head have been recommended. Epispastics are said to be serviceable. (Blisters have been found serviceable they should be kept up for a length of time) Mild mercurials cal. or blue pill & the muriate of lime or sometimes [illegible] pressure by bandaging . If the disease is accompanied by rickets the cold bath is indicated and has been found serviceable I have known one child recover from this disease and other who has been mending under medical treatment for 2 years past. I do not know whether it recovered # H. externus appears to be nearly allied to those watery tumours which affect the spine. In consequence of a partial opening of the sutures of the cranium, or the absence of a portion of one of the bones the dura mater and scalp are protruded by the pressure of the contained water & form a swelling on the outside of the head. Puncturing this tumour is suddenly fatal (is as fatal as the same operation performed on the tumor of the spine. Arachnoid inflammation, arachnitis, apoplexia hydrocephalica (Cullen) encephalitis phrenicula of Rush cephalitis profundu of Good We might multiply [illegible] but perhaps this is sufficient The disease different in different cases A great deal has been written and great deal of confusion exists “In this species of hydrocephalus the effusion of serum is into the ventricles of the brain. This serous effusion is the effect of the disease and not the disease itself & hence it may follow diseases of various kinds. I consider the name very improper” # “The vomiting if it cannot be ascribed to improper food in the stomach is an important symptom in the diagnosis” 165 Hydrocephalus Internus acutus Under this unfortunate name I propose to treat of all those cephalic diseases which are less violent in their action than phrenitis (or are less inflammatory). I shall principally confine myself to the disease as it appears in children “Symptoms different in different cases” The disease commences with the following symptoms (one form of the disease is well described by Dr Quin) vide [illegible] vol 2 p. 315 The patient is languid inactive and drowsy more or less feverish at times apparently free from any complaint (drowsy & peevish at intervals easy and apparently free from any complaint) The appetite is poor and irregular (week) & (Nausea &) in many cases vomiting # occurs once or twice a day. The skin “Exacerbation towards [illegible]” is generally hot and dry (towards evening) and if a perspiration occurs it is partial. Soon after these symptoms. The patient is troubled with a headach. The seat of the pain varies in different cases, sometimes it is confined to one side of the head (Soon after these symptoms commence the patient is affected with a sharp headach either in the fore part or crown) It is a common observation that the headache alternates with the affection of the stomach, the vomiting being less troublesome when the pain in the head is most violent. The pain occasionally attacks other parts of the body (& sometimes principally confined to the back of the neck and the space between the scapulae) At this period the patient is averse to the light, cries much & sleeps little While asleep the patient shows # “The tongue is commonly clean & in this respect this aff. differs from remittent bilious fever, in which the vomiting & febricula are attended with a yellow fur upon the tongue” One side of the face body one arm or one leg more affected or moved often is perhaps a severe a pathogen sump. as any other. This is an indication of paralysis I have known [illegible] patient recover from paralysis 166 signs of uneasiness grating grinding the teeth. starting and screaming in sleep as if terrified. The bowels are usually constipated though sometimes relaxed. The pulse in this early stage does not indicate much danger (These symptoms however are subject to great variations). These symptoms are succeeded by affections of the eyes. One eye is turned in ward to the nose its pupil is dilated The pupil contracted in this early & dilated in the latter stages. Sometimes both eyes at the same time are affected in this way both turned inwards & both pupils dilated. In this stage the vomiting becomes more constant and the headache more excruciating, the pulse is frequent and the breathing quick. # If these symptoms supervene to typhus fever, the pulse becomes more slow Exacerbations of fever take place towards evening. There is often a flush upon one cheek (flushing is usually confined to one cheek) Perspiration if it appears is usually confined to the head and chest. A discharge of blood from the nose at this time relieves the symptoms of fever (& removes the flush from the cheek) for a time & any favorable symptoms. Delirium often takes place at this time and is violent in proportion to the age of the patient All this time the disease is undergoing a change. As the disease advances the pulse becomes more slow and unequal & the patient becomes less sensible to (the pain in the head) his sufferings Lethargy succeeds the disturbed sleep and restlessness of the early part of the disease. The strabismus and dilatation of the pupils increase & the eye loses its sensibility Loss of vision (The patient after sleeps with one or both eyes half closed) The patient in this stage often takes medicine & # “Even in this stage patients have been cured by the strong impression on the system made by tartar em. pushed so far as to produce colic” vide infra Sometimes when hemiplegia takes place the disease puts on a chronic form In the 167 sometimes food will sometimes however he obstinately refuses to take any thing. The bowels for the most part continue costive. # To these symptoms succeed a quick small pulse (almost imperceptible) bad symptoms in the last stage sure forerunners of a speedy dissolution (a difficulty of breathing in many cases the flushing of the face is succeeded by extreme paleness sometimes in this stage petechial eruptions appear on various parts of the body & the patient dies in convulsions or sometimes a hemiplegia takes place two or three days before death The disease sometimes runs through its stage in 4 or 5 days at other times it requires as many weeks. The dilatation of the pupils in some cases does not take place until the last stages & perhaps sometimes not at all. In all cases the proper treatment should have been pursued before strabismus, blindness or coma takes place, because very little is to be done afterwards. A constant rolling of the head & moving one arm and one leg are among the most important early symptoms which indicate a dangerous affection of the brain) The disease sometimes puts on the form of an intermittent. When the disease has terminated in effusion the case is probably always fatal. much dissatisfaction after existed When an ordinary fever terminated in hydrocephalus thinking that the phys. was mistaken at first “I think this disease is rarely an idiopathic affection. It supervenes upon other diseases & generally depends on disease of the stomach & bowels” The disease when from ext. violence may exist without any [pathognomic] symptom 168 Causes external violence teething worms Other fevers forming a crisis by effusion into the ventricles of the brain. Typh. fev. & dysent. in children terminate in [illegible] I have known more than one instance in which it followed [illegible] of hip joiont This is very rarely an idiopathic affection unless it may be considered so when it arises from external violence Vide L. J Pringle on dis. of [illegible] When it does arise from external violence it rarely puts on the same symptoms or the same appearances after death All the diseases of children from infancy are liable to terminate by hydrocephalus & hence it is important to examine all the symptoms which may indicate a determination to the brain & check the tendency if possible Case A girl 14 years of age, had symptoms of affection of the brain from a fall upon the occiput she complained of pain in her head for two or three months before she died & occasionally had regular epileptic fits [illegible] [mouth] The pain the head was relieved by cupping and epispastics to the head, but she finally died in an epileptic fit On dissection the dura mater under the cranium, where the injury had been received was thickened and the vessels were injected with blood. The ventricles contained half a pint of water. Dropsy in the brain Yet the pat. had no dilatation of pupils etc. The dis. put on the appearance of epilepsy occurring once a month. More common in some families than in others 169 Causes. Hydrocephalus is a disease nearly allied to with scrofula & like that seems to run in families. Delicate children in whom the mental faculties are more early developed are more subject to it. Hence the common observation that the child is [illegible] forward that it will not live long I think persons of a scrofulous habit are more subject to this disease & that of the hip joint When there has been no local injury to the brain, the disease commences with affection of the bowels, or it is a sympathetic affection from disease of the bowels In the progress of bowel complaints in children, the [illegible] and the small veins become turgid. This enlargement of the vessels seems to invite the blood to that part. In consequence of this child may die with symptoms of hydrocephalus, from the turgescence of the vessels, without any effusion into the ventricles In typhus fever, in dysentery and in other bowel complaints of children it is not uncommon for children to die with symptoms of hydrocephalus It is a good symptom in hydro. to have a discharge from the [sch??der???] membrane 170 Diagnosis “In its early stage, this disease is scarcely to be distinguished from remitting fever When from the anxiety of relatives & of the physician, a diagnosis is eagerly desired, the following circumstances may perhaps assist in forming a judgment If there is occasional vomiting, with febricula the tongue at the same time remaining [illegible], there is reason to apprehend that the primary irritation has its seat in the brain and that it will prove a fatal case of hydrocephalus. But if along with the fever and vomiting the tongue is covered with a thick yellow fur, we may hope that the complaint is confined to the digestive organs and that the disease is nothing more than coler or remittent fever.” Ed.reviewer Diagnostic symptoms between idiopathic arachnitis or cerebral fever, and infantile remittent or fever from intestinal irritation choler In cerebral fever the abdomen is flattened, not tumefied but in intestinal fever it is tumefied. In idiopathic cerebral fever the secretions of saliva and that form the schneideran membrane are diminished. Unless complicated with aff. of muc. m. which is rare. In cerebral fever the tip and edges of the tongue are red In intestinal covered with a thick fur. In cerebral fever the pain in the head is severe and excruciating; in fever from intestinal irritation it is obtuse. # the sides of the head, back of the head on the forehead Perhaps a constant rolling of the head & movement of an arm & leg are among the most important symptoms Different opinion ben entertained about the nature of the disease Some have been so anxious about determining the exact nosological nature of it disease as to refrain from prescribing until the first stage has gone by. Prescribe for the symptoms at all events and make up your mind about the nature of the affection as fast as you can. Too much discrimination cannot be exercised & cultivated yet where we cannot determine the exact nature of the disease we had better treat the existing symptoms & the obvious indications # It varies in scrofulous constit. there is no such state It may approximate in some cases And I might cite the opinion of 20 others The [illegible] it is sometimes entonic & sometimes tonic. It more frequently [illegible] determined Why shd not fevers terminate in the brain as well as [illegible] 171 In intestinal fever the patient more frequently directs his hand to the nose & about the face in cerebral puts his hand to his head # In cerebral affections the head is hotter than the abdomen; but if the disease originates from the bowels the abdomen is the hottest. “There in a very few cases seen picking at the nose in cerebral fever but in general the rule holds good” “The state of the bowels is not pathognomic” Dr Beddoes thinks the disease belongs to inflammations & that at an early period he should be inclined to bleed as largely as in pneumonia # Dr Withering observes “in a great many cases if not in all, congestion or slight inflammation are the precursors of aqueous accumulation Dr Rush thinks that instead of being considered an idiopathic dropsy, it should be regarded only as an affect of primary inflammation or congestion of the brain “Dr Rush says” It appears that the disease in its first stage is the effect of causes which produce a less degree of that inflammation which constitutes phrenitis & that its second stage is a less degree of that effusion which produces serous apoplexy of the brain Dr Darwin supposes torpor or inactivity of the absorbent vessels of the brain to be the cause of H. internus Dr Whytt in his treatise on the disease observes that this and every kind of dropsy depends upon the fact that more fluids are thrown out by the exhalants than [illegible] the absorbents take up I chiefly depend upon calomel for a cure if it cause too much evacuation check it with opium There is no evacuation from the brain therefore the disease must be overcome by altering the secretions counterirritation etc. Bleeding with leeches from the temples seems to translate to the surface and give relief vide John Hunter. Case young man apparently as desperate a cure as ever I saw not scrofulous we concluded to try tart. emet. gave it without much weight in about 8 or 16 hours he complained of violent pain ion the bowels and all the symptoms of the head were relieved [illegible] “Irritant to the schneiderian membrane in the last stages are recommended by Dr Malachi Foote of N. Y. in the Med. Rep. for about 1810. Turpenth min. 1 gr. with liquorice 20 grs [apreynum] [myrici] ipecac etc. are the best [stermentatories]” 172 Treatment Evacuants Bleeding general & local cathartics calomel and jalap gamboge Counterirritation local bleeding cupping epispastics behind the ears and to the whole surface of the head Salivation should be induced but cal. often relieves without altering the secretions There has been a difference of opinion as to the application of epispastics to the head. If venesection be indicated they should not be applied until after bleeding. I prefer cupping and blisters to the back of the neck and behind the ears I think some advantage may be derived from applying to the spine ol. orig. ol. capsc. etc. Where considerable entonic action has existed I have cured this disease by giving tartar emetic until colic was produced. give perhaps a grain & continue its exhibition until the symptoms abate # “gr doses every 2 or 3 hours” Sneiderian membrane dry snuff malachi root Irritants applied to the schneiderian membrane have cured the disease in its last stages Rx 1 part turpenth mineral & 10 parts powdered liquorice for a [ster??tatory] Green tea is sometimes given In the progress of the bowel complaints of children the sinuses may become enlarged & a determination of blood [illegible] to the brain and produce symptoms of hydr. I have known pat. apparently die of hyd. & yet upon dissection no water be found in the [ventricles] in this case some say that the water was absorbed in death this is entirely improbably. Certainly many of the symptoms of hydr may be prod. by other causes e.g. excessive doses of narcotics is stramonium belladonna It shd be remarked that many cases supposed to terminate in hydr. in cases of [termination] in volvulus “All the diseases of children are peculiarly liable to terminate in hydrocephalus. Hence the importance of caution on the part of the physician. He should examine all the symptoms to check the first beginning of determination of diseases action to the head V.S. keep the bowels open blisters behind the ears cupping leeches” 173 Hydrocephalus from bowel complaints If in the progress of any of the bowel complaints of children morbid action should be determined to the brain, Epispastics should be applied behind the ears and irritants to the feet Cathartics are useful to obviate this determination. # In some cases perhaps the determination [marise] from nervous irritation. In such cases the tepid bath gives relief “Strong green tea” Some physicians of respectability have in formed one that they have used digitalis in hydrocephalus with very good success. I have not used it myself but should consider more adapted for that form of the disease which arises from irritation, than any other Hydrocephalus from disease of hip joint. Child of Ezra Hotchkiss child of Horace Edwards. “I have known hyd. alternate with disease of hip joint Case Narcotics etc. till suppuration” Afterwards died of hydrocephalus # I have cured a patient by giving him calomel and lemon juice in sufficient quantity to move the bowels. It increases the secretions and improves the tone of the bowels “I have seen a case in which the child fell 8 or 10 feet upon a pavement & broke his skull like a squash shell yet he recovered in 2 weeks and did well. When the fracture is so extensive there is less danger of compression of the brain” The same case? Hyd. from injury by a fall is not common in young children the sutures are not firmly closed (the bones are softer & more yielding)( # He had other severe wounds as a compd fract. of the radius yet he never suffered his head 174 When the disease is produced by violence Depressions of the cranium in children from blows or falls are not of course fatal though dangerous. A child four months old fell head foremost upon the hearth striking upon the vertex. The head was much flattened & the parietal bones bulged out on each side. The child did not suffer much from the injury. The bowels were kept open by mild mercurial purgatives. In these the head assumed very nearly its natural shape. A boy of eight years fell six or eight feet and struck his head against a stone A depression of the cranium was made larger than the bowl of a spoon. He suffered very little inconvenience from the injury # There is less danger when the skull is so much fractured as not to cause pressure upon the brain If a child has received a fall we may apprehend danger from the following circumstances. If the fall has been upon the occiput the brain is more commonly injured than if the face is upon the os frontis. If the child vomits after the fall and is very sleepy there is danger that the brain will suffer. Treatment If the child vomits or is comatose after the fall upon the head and there is no wound that bleeds the patient should lose blood and take a dose of calomel, one or both according to the urgency of the symptoms & the death of the patient. All the exciting causes of fever should be avoided and the patient kept as quiet as maybe. The symptoms should be carefully watched and if at anytime there should appear to be a tendency to an affectation # for local bleeding is as important a general bleeding “[illegible] all causes of irritation, as light noise heat, food. Keep the pat. perfectly quiet” “Apply an epispastic behind the ear, or better upon the injured part.” “Blisters are very useful” “Use counterirritation & the tepid bath” # In torpor of the br. [illegible] al. can excite the latter may excite the former and excessive action in the former may be translated by it act on the latter “Give strong cath. cal. gamboge jalap etc.” “Afterwards give cal. in small doses as an alterative If it causes too much evacuation check it with opium” “In N. Haven we have followed Abernethy’s plan of treating infl. of brain for 40 years” 175 of the brain the patient ought to be bled & leeches or cupped. # The bowels should be opened with calomel and small doses of the same remedy frequently given as an alterative After depletion epispastics may be applied behind the ears and upon the part of the head where the injury was received. There is no outlet to the brain & consequently more evacuants are needed than in most diseases Frequent cathartics are useful as evacuants and also to translate action from the brain # When effusion has taken place the case is probably always fatal Yet I have had a pat. with dil. of pupils, who cont. so & paralytic for months & finally recover Vide p. 200 The treatment consists of local applications A variety are used One of the best is [illegible] zii alc. zi An equally good or a better application is seneka oil but the smell is disagreeable. Cold water is applied but though it relieves the pain and the insupportable itching it is doubtful whether it is of any permanent benefit Basilicon [illegible] [illegible] absorbents to ulcers 176 Chilblains Pernio This is a local affection to which children and old people are most subject. Some are much more liable than others. [illegible] [illegible] more liable. The parts affected are the toes heels fingers, hands face, ears and with ladies who wear short sleeves in winter. It is caused by exposure to extreme cold & to cold & damp air & on the feet, more especially by walking through melting snow. It is most common in the early part of winter This affection should be prevented by avoiding an exposure of the parts to the air, by keeping the hands warm with soft leather gloves & by keeping the feet warm with stockings and shoes The skin of the part affected becomes tumefied and hard & of a deep purple colour, there is a pungent pain in the part accompanied with an insupportable itching; & these are often so great as to prevent the patient from sleeping. If the disease advances, the cuticle breaks and discharges a thin fluid. Sometimes a deep ulcer is formed The treatment for the first stage should consist of stimulating application as if for a burn. I prefer oil of origanum alcohol & seneca oil are good applications. Spirits of turpentine will ordinarily do well, though in some idiosyncrasies it acts as a poison. Cologne water may be applied or alcohol two parts with one of ol. orig. # For the ulcers you may use the oxygenated ointment ointment of red precip. citrine oint. # or apply a plaister Dyachylon or Noel’s Not being able to have any fire on board for some days [illegible] to pain of a neuralgic kind as [illegible] were a toothache One of the best applications is a cataplasm of stramonium seeds give internally opium narcotics & stimulants Apply [illegible] & narcotics Followed by no infl. to supp. etc. 177 Painful affection from cold We sometimes meet with a painful affection of the feet without discoloration, or any other visible mark, which has been brought on by long exposure to cold without freezing. Sailors coming upon our coast from the I. in winter, from a warmer climate are liable to it. The affection may be a very painful one and give great uneasiness both night and day It is relieved by the external application of stramonium & epispastics or rubefacients, and fomentations Cathartics and opium may also be given internally. Singular effect of cold in Wm Daggett Burns are dangerous in proportion to their extent [illegible] young physicians are called to prescribe for burns it is important for them to treat them in the best manner About 30 years ago a great controversy existed in England between those who advocated [stimulating] In recent cases stimulating or exciting applications are the best provided the burn is not very deep. About 30 years since spts turp. were much used. It in some case and these are not very rare Case myself [water] boiled over into my shoe I immediately poured spts tupr upon the stocking then took off the stocking applied a cloth dipped in spts turp. put on a dry stock. & boot rode out of town and suffered My father was a man of florid complex. & thin skin He was burned in n a similar manner Ol. orig. Linseed oil is smooth mixed with limewater alcohol or proof spts good when the skin is [illegible] off Others use camphor Others stramonium in ointment contain what [illegible] when the article s off Carrot poultices etc. exclude the air Cotton does well except when the cuticle is off if it is used then you had better smear it with oil 178 Burns This subject belongs more particularly to surgery, yet as burns occur most frequently among children, and you may be suddenly called in on such an occasion, when it is important that a remedy be speedily applied. I have thought proper to make some remarks on the subject. For the treatment of burns very different modes have been recommended. A long controversy was carried on in one of the English journals with respect to the phlogistic or antiphlogistic treatment, one party being in favour of cold applications in cold water and the other of stimulating ones as spirits of turpentine The truth seems to be that in adults where the injury is not extensive and the powers of life are strong cold applications do well, but they are dangerous for children especially if the injury is extensive. Burns upon the abdomen will not admit of cold application even in adults It is necessary that reaction take place If there be no reaction of the system, no pain, no inflammation the child dies. The cause of its death is the irritation of the nervous system, extended to the stomach, & hence the death is preceded by cold extremities and vomiting Where cold application are proper such applications may be made as scraped potatoes, cloths wrung out in cold water etc. But if it is necessary to produce reaction and inflammatory action stimulating remedies must be used. And we know from experience that these remedies do effect a speedier cure Cold applications may do well if immediately e.g. dip a burnt arm immediately into cold water. But stim. app. are better. I have tried both. Cold applic. very dang. in extensive burns of children Case scarped potatoes no infl. livid appearance of the burn extrem. cold [illegible] death In such cases apply stim. app. & give ether, elix. [illegible] etc. etc. In these cases the child dies of irritation not infl. It seems to be necessary for a regular [course] of continuity of action in infl. & suppuration The best and mildest application as has been proved by experience is petroleum or seneca oil In one case I tried the experiment of applying seneca oil upon one hand & ol. orig. upon another (both being known alike) one hand was easy the whole night the other painful (the burn was a very extensive from the clothes taking fire) In the suppurating stage use 1 part seneca oil & 3 parts cerate These cases are very troublesome to treat In the above case the system was exhausted by the extensive suppuration the bowels had to be kept open & large quantities of opium to be given. I gave columbo bark and various tonics and aromatics Turner’s cerate is a good application chalk may be sprinkled over it In the progress of the suppuration a pale flabby fungus almost like a blister and is difficult to manage I have applied a sol. nit. sil. also nit. sil. & laudanum [illegible] cop. sometimes after these I have succeeded with ac. op. in ointment green basilicon i.e. verdigris ground fine & mixed with basilicon But if you apply only applications after these caustics 179 The reason is that we apply to the part a stimulus less powerful than that which produced the injury and thus render the diminution of the excessive excitement gradual. On this principle holding the injured part near the fire is beneficial Another important indication in the treatment of burns is to exclude the irritation of the external air Hence the popularity of some applications as cotton. sweet oil etc. 1st Of stimulating applications. Spirits of turpentine will answer for a robust and healthy person but not for a slender & feeble one; and it must be remembered that from a peculiar idiosyncracy it is a poison to some persons. In general spirits of turpentine is liable to cause irritation and may be suspended by better articles. Being burnt myself a complete cure was effected without the least appearance of inflammation, by this article but in the case of my father such violent irritation was produced as to oblige him to desist from applying it A common remedy in this town is the oil of the origanum majorarum called burn oil mix ol. orig. zii with ol. oliv. zi or mix it with alcohol or cerate. Cloths may be dipped in the diluted oil and kept constantly applied Of late years I have used seneca oil and prefer it to either of the two already mentioned. In several cases I have tried both this and the ol orig. & found that the seneca oil relieved more speedily & with less irritation. I usually apply the seneca oil & the fungus [illegible] Apply rather chalk or fine alabaster or scorched flour The sooner you apply stim. appl. the better ol. turp. produces [illegible] etc. seneca oil does not Case a woman thief etc. etc. we rolled immediately in the snow was thrown by it into a state of syncope life almost extinguished was burnt universally except on the legs covered by the stockings was wrapped in sheets dipped in a mixture of ol. orig. & spirits 180 then cover the part with cotton to exclude the air. I let them remain till suppuration takes place, particularly if the skin is broken. When suppuration takes place, apply a poultice to the loose dressings and then apply simple cerate or a cerate made by melting together beeswax and lard and stirring in seneca oil while the mixture is cooling This last is an admirable application for burns Dr [Mons??] said he knew none so wild. It protects the raw surface from the cold air and keeps in the animal heat In the latter stages of the cure, the oxygenated ointment will be a soothing application A popular remedy is stramonium, used in the form of a plaister of the seeds or leaves. It answers well and I have known no ill consequences to happen from its use though it is said that in extensive burns it is dangerous Cotton is a popular application, used by itself For slight burns it will answer but if they are so extensive that suppuration is to take place, it should not be applied in this way Other remedies that are useful upon the principle of excluding the air, are the oils as sweet oil & lamp oil. Linseed oil mixed with one third part lime water, is especially recommended When suppuration takes place and the cicatrices do not form well, oily application should be laid aside and if there is considerable discharge apply absorbents, as plaister of paris, chalk & chalk & cerate i.e. apply chalk first & cover with cerate. Note from Dr Woodward of Wethersfield extracted from Dr A. Talcotts notes “Apply immediately spts turpentine to the inflamed parts and cerate of limewater & linseed oil equal parts on cotton to the vesications 2nd If pain & irritation ointment of stramonium 3d To prevent fungus Rx white lead a teaspoonful lard 2 tablespnfl. ft. ung. Orgrate or chalk and apply simple cerate over it. I have seen a metastasis at the end of a week to the bowels with diarrhoea & tumefaction or the bronchia with croup Treat with opium & bark Dr S. B. Woodward” N. B. I extracted this principally on account of the definite direction about the difficult treatment required according on the burned part is vesicated or not a point on which the above notes of DR Ives do not seem to be sufficiently precise 181 Should there be a fetid discharge from the burn, it may be remedied by pulverised charcoal. Sometimes the ulcers are very difficult to heal and repeatedly break out afresh A fungus may arise upon the part if so it should be touched with caustic. The eager of the ulcers may be touched with sulph. copper or nit. sil. chalk then applied and the whole covered with cerate. If the burn is on parts liable to unite in healing, as between the fingers and toes, care should be taken to prevent the union. A bad cicatrix is often formed which it is difficult to prevent or cure. Internal Treat When the constitution has received a severe shock and the extremities become cold and the powers of life being to fail, the system must be supported by stimulants & cordials & the excessive irritation relieved by opiates. Laudanum ammonia, spirits, alcohol ether are all good. To a child from 5 to 10 years old 15 drops of laudanum may be given; warm-applications may be made & warm aromatics drinks as ginger tea & mint water administered. Elixir paregoric is one of the best preparations of opium in such cases In a case in which a large quantity of sulphuric acid had been drunk by a boy who immediately afterward, ran to a brook and drank of the water. I merely give mild mucilaginous drinks & the patient being of a strong constitution recovered 182 Croup from p. 138 In what may seem to be the second type of patient may go off suddenly. If he throw his head back in order to enlarge the chest it is a bad sign I have found the treat. by tart. ant. so infallible in the first stage & in general so useful that I have not been tempted to desert it. If I am called rather late and find ext. ant. acting locally upon the stomach, I seldom succeed in curing the patient. Other emetics may be used when the excitability is worm out for [illegible] Calomel is proper in the latter stages, [illegible] the disease is partly broke up by antimony If the first stage is not interrupted [illegible] the child may be playful between the paroxysms and though the pulse is not affected, yet the second will surely come on In the second stage bleeding is to be first resorted to in order to prepare for emetics bleed even to fainting conjoining the warm bath for the same etc. Exciting and irritability [illegible] in this second stage do mischief. I have seen sanguinaria do much mischief. Even after bleeding purges is not advisable for as has been remarked there is a constant tendency in the system to the return of this inflammatory symptom Cal. may be given though if it act by the bowels it will be useless. I have seen bleeding and the vapour bath palliate the symptoms. Scarcely ever will the patient recover 183 Croup In the latter part of the last stage the child throws its head back. This is a dangerous symptom. Now the patient goes into the last or suffocating stage. The patient lies on its back struggles violently for breath countenance livid appears apoplectic and often goes into convulsions and in these convulsions sometimes dies Sometimes in this stage you may hear a flapping of the false membrane. This is sometimes thrown up and great relief is afforded and the friends think that all is over. Soon however in most even of those cases a membrane is formed lower down & the patient ultimately dies In this stage the metallic emetics have in a few cases succeeded The sulph. cupri & the sulph. zinc have each cured Cal. is recommended & may be used The cold both has been recommended It may be tried as a dernier resort. In the second stage after bleeding blisters shd be applied over the whole neck & chest Dr Hosack recommends bleeding from the back of the hand immersed in warm water After bleeding has succeeded in subduing the symptoms cal. & the warm bath shd be used 184 Croup This disease has been divided into acute & chronic but without much propriety Sometimes it continues for some time. I have known one case which continued 3 or 4 weeks In some seasons a different mode o f practice is better. I have known seasons in which cath. & diaph. were the best treatment Although for the first 15 years of my practice I considered nothing more unfortunate than to find the child under the operation of a cathartic. In these cases, it was the form in which the duodenum is also affected in a similar manner Case Wallingford [emet.] failed & cal. & diaph [illegible] Others that season occurred which required the same treatment Bronchotomy has been recommended I have seen it performed but never with success It has sometimes succeeded But in the cases which I saw the membrane form lower down, and the patient die 186 You will see by looking into the throat the tonsils perhaps red & the epiglottis certainly inflamed 187 Angina Laryngia Another form of the croup has been called angina laryngia [illegible] the croup you can see nothing by looking into the throat In this the epiglottis & the [illegible] glottidis are affected From the larynx being affected, the actions & more spasmodic Frequently comes on while eating Case of my child While apparently well was taken while eating with the peculiar croup & respiration of croup & became alarmed & treated This is the form which attacks old people probably Geo. Wash. died of it Case The first time I saw this disease the pat. had had pneumonia & may nearly recover when he went into the cold open air without stockings. I was informed that he was taken with difficult respir. & without seeing him prescribed seneka injurious ultimately refused to swallow anything as the act brought on a spasm I tried bleeding, blisters, vapour & after awhile persuaded him to swallow when I gave him 4 gr. tart. ant. in a cable spoonful of water 188 Angina Laryngea The dis. is brought on by eating And if you examine the throat you will see a redness perhaps upon the tonsils, and will certainly see the epiglottis inflamed Bronchotomy promises more in this form of croup Readily distinguished for the other by difficult deglutition paroxysms being brought on by an attempt to swallow This firm It is not of much consequence to distinguish the forms except that laryngea is more rapid And you must avoid acrids in this form as they irritate the fauces & produce spasmodic action For the spasmodic symptoms give in the latter stages of it asafoetida which also acts upon the secretion tinct. ant. & opium It must be remembered that this disease cannot be cured by bleeding alone. It is too far out of the circulation. But by reducing the system very 189 Croup concluded When croup follows other diseases it is more rapid and dangerous they are very apt to die particularly when following ulcerated sore throat You may treat by emetics blisters metallic emetics etc. but you have not so much strength left in the system to act upon In the latter stage where we wish to throw up the membrane the stomach may lose its excitability to a particular emetic then you are to change the em. I have succeeded in throwing up Upon dissection a membrane is found formed But sometimes it is wanting and in A laryngea then probably is not [time] for a membrane to form Vide p. 211 low and suspending the functions you may change the secretions perhaps 190 191 Scarlet Fever Withering in his first edition separated ulcerated sore throat from scarlet fever. In the second he changed his opinion Where there is much heat and fullness of the pulse I would much prefer a strong dose of cal. followed by antimonials [to] commencing with emetics Or is Dr Rush & the elder DR Barton thought best turpeth mineral Epispastics are to be used with caution & adopted this rule viz to apply them where there is much tumefaction [illegible] & enlargement approaching the quinsy. Scarlet fever after resembling quinsy and is with difficulty distinguished except from the previous affections of the family and neighborhood Mineral acids have been considered specifics Chlorine was much used in this town in [1801] etc. as a fumigator. You may give it internally with advantage A great variety of gargles are used generally stimulating ones are better as those of capsicum (with salt say in cider water) In some cases capsicum does not do well If the patient is too weak to gargle use a syringe 192 Scarlet Fever Chlorate of potash was used with advantage to quiet the stomach. It allayed irritation etc. Ammonia and amm. with camphor & gum arabic In the progress of the disease mineral emetics, as sulphate zinc will be useful to excite the system acting speedily they do not exhaust sul. zinc 5 to 20 grs mosely’s solution was the form most used Sulph. copper 2 to 5 gr. also as an emetic Acetate of copper was formerly kept as a nostrum in some families ½ to 1 t. sp. of sat. sol. of common verdigris 2 to 3 gr. In some cases and seasons cath. are required. I have treated children without a single cath & yet in the same family I have given ant. followed by cal. & worked off by salts and senna If a diarrhoea occurs early it must be attended to white decoction 193 Scarlet Fever Dr With. lays great [illegible] upon diuretics particularly senega giving it throughout the disease. In moderate fevers diuretics eliminate morbid action will Serpentaria may be given freely throughout the disease adding bark alcohol ether or wine Diuretics & diaphoretics Irritable state of the stomach is to be counteracted by irritants by aromatics white decoction etc. etc. a little alcohol upon the fauces voiding a great bulk of liquid Case of a boy in delirium his father was forcing down articles which he was puking up I put into his mouth spoon dipped in brandy 20 or 30 drops his eyes opened immediately said it was good continued it in tspfl doses through the night saved his life Scarlet fever occasionally passed by insensible gradations into quinsy and is of an inflammatory character. No one character will distinguish them No one mode of practice will answer in all cases though if any indiscriminate mode of practice is to be followed that by emetics and stimulants will be best In many cases no evacuations at all are to be used if this you must judge by the symptoms In the same family I have lately treated one or two patients with antimonial and nitre and another who had been worn down by fatigue and watching with feeble pulses vomiting coldness etc. was treated by external heat, brandy in moderate 194 Scarlet Fever quantities, counterirritants spiced tea etc. to stop the vomiting # (One of the best articles in fevers of a low grade is spiced tea or hot spiced wine or brandy. The strength is apt to give out first, and an excitement kept up in the mucous membrane of the stomach will have a beneficial effect) # The first patients in this family I had evacuated freely both by vom. & purging etc. while this patient had no evacuation goodness & was supported throughout the whole progress of the disease After I had seen the disease in 3 or 4 epidemics I thought I had seen the disease in all its forms but I found oftenwards that I met with different forms still Not only different epidemics differ, but different cases during the same epidemic may require widely different treatment In the malignant epidemic of ’94 I was informed by some physicians that they met with cases in which there was increased action though the many cases of the epidemic ran rapidly in the [illegible] gangrenous state In 1803 we generally gave emetics It is said that in the malignant form the eruption is a bad symptom. I do not think so. I think it better for a general eruption to come out the action is less unequal than if a scanty or no eruption appears I hesitated in 1803 much about the application of blisters & I finally found that the rule was a safe and beneficial one to apply them where there was swelling of the tonsils In this epidemic I gave bark, the mineral acids, alcohol, wine, and (for the first time) tinct. canth Tinct. cant. [illegible] zi to pt. give 20 gtts once in 2 hours ½ as much to a child 195 In many cases [illegible] requires to be qualified & corrected by serpentaria or carb. amm. If wine injures the stomach and [illegible] too locally continue carb. amm. which will render it diffusible with white vinegar will have somewhat of an effervescing mixture Use also effervescing mixtures, as soda water, with brandy or ether, or aromatics tincture. It is no objection that you thus combine stimulants and refrigerants, for you thus get diffusible action and obviate unequal excitement. The min. acids may be given in form of punch The sugar will be grateful & useful A diarrhoea is apt to take place in the commencement of the disease. Use white decoction laudanum & injections of starch & laudanum RX starch 3 bal. sp. SS. 30 gtts to 2 t.sp. Pay great attention to cleanliness of the patient Where there is fainting apply ammonia and ether & spirits at the nostrils keep them applied to the nostrils to prevent fainting, I have never known any injury done by over excitement by these articles thus applied Capsicum is used in tropical [illegible] in very strong decoction. Salts and vinegar has been much used as an antiseptic gargle? For the diarrhoea use tonics, bark, contrayerva has been though valuable. Avoid injuring the stomach by distention 196 A variety of garbles (or injections by a small syringe) are used. [illegible] rosemary has been thought a specific & carried hundreds of miles into the country Use others when pat. is disgusted with one # Sulph. cop. ac. cop. nit. sil. ([touched]) apply these with a swab What is called the leathery inflammation is sometimes met with. in which the skin dies at first and afterwards comes off & then a discharge follows. This affection sometimes extends down the throat. In such cases apply blisters to the sternum Touch the part with nit. sil. in such cases. IN one of these the blister on the sternum produced an ulcer which was 3 mo. in healing and in another though the affection with throat was relieved the ulcer for the blister destroyed the little patient # [illegible] oak bark etc. pomegranate combine brandy aromatics etc. It might to be remembered that in the latter stages of ulcerated sore throat where there is an accumulation of [many] a phagedenic ulcer, emetics of sulph. zinc give tone and excite action also when Acetate copper in the latter stages used in an emetic as a tonic or locally applied as a caustic When the stomach fails in the latter stages we give capsicum in pill or strong infusion (2 tab. sp. to the pt makes a strong infusion give to an adult a tablespoonful also acrid oils There seems to be an erythematic infl. of the mucous 197 membrane of the stomach hence acrids are indicated to excite action Bark jacket also it seems to have some effect In the latter stages also a cath. will frequently be beneficial an accumulation of feces may exist given mild cath. as castor oil or perhaps a dose of cal. an emetic also may be needed One thing to be guarded against in young children is the supervention of dropsy In 1803 I had 3 cases all the writers considered the disease as one of weak [illegible] action and requiring tonics bark etc. Not successful Bark does not generally do well when there is unequal action I have known in such cases the brain & nervous system apparently much affected I have given in such cases digitalis and cantharides to produce as new excitement and ally this irritation in the nervous system Case related patient very low from a disease digitalis was given and elaterium being advised was given when the patient died upon the second evacuation In general treat these cases with diuretics a moderate use of cath. narcotics & remedies etc. Digitalis is the best narcotic but be cautious giving it to children In ordinary cases of such dropsy a cath. will remove it and frictions & exercise in the open air. Various articles are popular as ol. [mor] [199] [illegible] ol. gaultheria various irritants etc. and to encourage the attendants to persevere in rubbing you may suffer friction to be made with these mere dry friction though probably just as good does not seem to them like giving medicine Various astringents may be 200 Hydrocephalus The management of the pat. is equally important with the medication avoiding in proper diet alternatives of temperature, and all debilitating irritating and exciting agents all the exciting causes of disaster. Sometimes a patient may (after a fall perhaps) continue one two or 3 years not entirely [illegible] and yet not quite sick and finally die of eff. of the brain Sometimes in strumous habits canth. internally may be advantageous Blisters translate action The applications of remedies to the Schneiderian has been thoroughly treated by Dr Malachi [Foot] in the N.Y. Rep. about 20 years ago. The subject has not bee sufficiently attended to Give in the way turpenth wine (mixed with liquorice) verat. vir. apreyn. [illegible] myrica cerifera etc. If a discharge can be excited relief is afforded Salivation can rarely be produced in children In some cases where there is paralysis the acrids and some of the narcotics as strychnos Blisters are applied by some to extreme parts of the body I sometimes change the place of the blister to the back of the neck etc. But the back of 201 ears is more efficacious. It seems to have a grater affect upon the constitution to excite a discharge from this part If the symptoms indicate bleeding bleed leech also. If there is much infl. about the mouth scarify the gums as a depleting measure “In grade of action the fever of hydroceph may vary from high entonic inflammation or phrenitis to low strumous fever. If the action is too high or too low counterirritation will fall in with the morbid action We must first bring it to the “blistering point” (Rush) “Blisters to the head are thought by some to be dangerous and the ears or neck preferred” “In irritable cases and scrofulous habits, strong cathartics are hurtful. Give blue pill especially when the bowels are primarily affected. But in entonic phrenetic fever, use the drastic cath. & tart. ant. ut supra after depletion” “Scrophulous predisposed mesenteria glands generally affected the fever analogous to hectic never entonic pulse soft, frequent, quick I have tinct. cantharides with advantage in this variety” [204] Volvulus continued from p. 89:a:1/2 “Cases I was called to a child 2 years old which had symptoms of irritation and was obstinately constipated It had been carried on the belly upon the shoulders of another person Gave a cathartic Ordered an injection but the attendant said it would not [illegible] The cathartic was thrown up patient died Upon examination after death no color could be found. In the upper [illegible] rectum there was a tumor which seemed of solid flesh as large as the doubled fist inflamed. The color had been completely removed from its place” “I was called to another family where the children had died when 5 or 6 months old as was supposed of an affection of the brain. This child appeared well when born but was very costive etc. Upon p.m. [illegible] 2 inches of the small intestine were found contracted to the size of a goose quill the coats were thickened & the course the cavity must have been extremely small This contraction undoubtedly existed at birth. This contracted part was received into the part below it, and no [illegible] could have availed” from p. 99 ½ “In another family they had lost all their children at about such an age. They supposed the disease to be hydrocephalus. The older physicians called it so. I told them I could not tell what the disease was but it was not hydrocephalus I had then seen no case of volvulus. There were strong 205 marks of irritation the face was pale and much distress was depicted with countenance the head was rolled back and hands tossed violently. There was vomiting and tenesmus and a discharge of mucus streaked with blood Cathartics had been given under the impression that the disease was an affection of the head The cathartics aggravated the disease which ran a rapid course and the child died. The small intestine was found received into itself and its cavity obliterated. This obliteration of the cavity would not of itself cause death; for a patient may continue several days with perfect torpor of the bowel. It is the irritation as in cholera morbus which is the immediate cause of death which [illegible] death usually occurs within 24 or 36 hours” “Called to a child one year old constant vomiting stool, mucus streaked with blood Directed mucilaginous injections & fomentations combined with opium Gave opium freely internally 10-15 minims to allay vomiting. The symptoms subsided gradually & in 3 or 4 days the feces passed off without any cathartic” “Was called to an Academical student had given cathartics and they did no good. Called in older physicians. They were in doubt respecting the case and advised not to do any thing as we might do hurt. As I was sitting by his side I heard a motion in his bowels. I noticed that it passed down to a certain point and then stopped. Upon examination I could distinctly feel the involution. I tried injections and some [illegible] of them would stay. Ordered a spermacetic candle with opium upon its extremity to be passed up the rectum and allowed to remain. It was s 206 passed in to the length of 10 inches. The opium allayed irritation and the application by repetition replaced the part & the patient recovered another case cured by a bougie” “Opium by taking off the spasm and restoring the natural function of the bowels may be said to act as a cathartic just as in spasmodic colic” From p. 56 “I have given when I could obtain it, the [resin] of Mandrake podophyllum peltatum It operates kindly, and more certainly than any other article. If the western gentlemen who have so much mandrake and whiskey, would furnish a supply. I think it [will] supersede every other article” “If there is torpor & a stuffing or infarction of the bowels we must use injections to assist cathartics repeating them every 2 or 3 hours. If other cathartics do not operate give castor oil which will promote their operation” “The particular kind of injection is not important and may be left to parents Thoroughwort, camomile, mayweed catnip, dandelion, weak soap suds salt & water a tablespoonful to ½ pint water 207 Continued from p. 57 “The stools resemble meconium. In the progress of the disease they exhibit small pieces of a membrane of a dark green colours, about the size of the petals of peach blossoms floating in a dark green fluid. The membrane of coagulable lymph, resembles that formed in angina trachealis and sometimes as in that disease it is formed in such quantities as to cause obstructions Still in this case it may not destroy life the action of this part not being so immediately essential to life. Stools of this kind sometimes attend the bilious colic of adults. They are an indication that farther evacuation is needed Continue the calomel or combine it with magnesia or soluble tartar, or phosphate of soda or other neutral salts 208 Infantile remittent continued from p. 60 “Cases A child had violent fever gave calomel & cathartics warm bath symptoms abated. In 2 or 3 weeks the regular symptoms of hydrocephalus appeared; & the patient seised in the greatest danger. In a short time these symptoms were relieved by a violent and dangerous attack of thrush The patient was very much exhausted lay several days very low gradually emerged and after a long course recovered. “Case of a small little boy 5 or 6 years of age After 5 or 6 days head affected & became maniacal very irritable and cross swore profanely would bite and strike all who came near him. If any thing was attempted to be administered he would shut his mouth. If his mouth was pried open he would close his throat with his tongue Advised his parents not to trouble him nor notice him to pass by him with drink roasted apples etc. but not to offer him any thing. The first day to he took nothing second day took roasted apples etc. readily but ate too much mania returned, but soon went off & patient recovered” “In one case the pat. took nothing for a length of time. Recovered by use of [even ato] & external applications as aloetic plaisters to the bowels etc.” Scrofula continued from p. 163. “Scrofulous swellings are very difficult to excite to suppuration I have however then poulticed without effect for 2 or 4 months Of late I have disused poultices & have applied blisters as soon as may be to excite invigorate the absorbents and act as discutients. They do not disturb the system. If there is suppuration the relaxed state requires stimulating applications lunar caustic vegetable astringents etc.” “Case of a young act 18 with bad cough swelled neck scrofulous temperament Gave laxatives blue pill afterwards rub & spec. Then gave decoction of [cistus] [canadensis] for several weeks and pat. recovered “ A physician (Smith) on Long Island (from an old recipe) has acquired reputation by the use of cistus canadensis combined with uva ursi at the same time enjoining a strict & spare diet as in dyspepsia” “I have given with cist. canat. 1/8 gr. corr. sub. & also decoct. scroph. maril. which is thought by the vulgar to be a specific It has been sold as a nostrum to facilitate parturition called nerve root.) I think it useful in scrofula” “I have known the comptonia [illegible] folia given internally. It is tonic & has balsamic rpoperties” “The remedies particularly indicated are tonics & deobstruents such as will not produce congestion such as uva ursi cistus scrophuloria contrayerva agrimonia (entire plant or root angostura etc.” Sea bathing is recommended, but if the lungs are affected, it will not be advantageous. A sea voyage to the eastward has been of service the constant motion of the vessel stimulating all the vital organs to healthy action The change of air is beneficial & at a distance from the shore there is no danger of taking cold In chronic complaints attended with a want of vital energy I direct a voyage to the east rather than to the south Croup continued from p. 189 “Vapour bath Inhalation of warm water in a [pour] blow a current of air through hot water upon the pate & by means of a coffee pot with two spouts” “Tobacco or snuff applied to the patient” “Croup is an epidemic disease & of course it will vary at the different periods of its appearance We must take into account the prevailing diathesis I have described the disease as it has usually occurred in my practice” “The proxim. cause of the dis. is a peculiar morbid action translated to the traches for the disease arises from general causes acting on the system. In catarrh diseased action is seated primarily with mucous membrane. The exciting causes of croup act on the surface and with different diathesis the same crises might produce pneumonia, dysentery enteritis or cephalitis “Disease determines to the weaker part as the rod attracts lightning” Rush Water & snow cold damp air a [illegible] & low situation sudden changes as when the wind blows from Canada or the gulf stream are the exciting causes “In the treatment sanguinaria, if given early in strong decoction very freely, so that enough of it shall be given & still it vomits or relieves the symptoms, in very efficient practice adopted by Drs Jared Potter & Kirtland “But if inflammation has taken place & the second stage has arrived seneca and sanguinaria are both too stimulating and I have seen them do hurt sanguinaria is less stimulating than seneka For p. 137 “Some authors state that the disease is entirely inflammatory not regarding the forming stage. If the forming stage is wanting we must rely solely on the antiphlogistic treatment” “This disease has a direct tender eye to death The physician must take it out of the hands of nature” “When croup supervenes upon catarrh as it frequently does of late year the mucous secretion and expectoration usually cease suddenly “When croup follows diseases that prostrate the system powerfully as angina maligna, there is little chance for recovery. The sympathies of the system are broken down and Archimedes can find no fulcrum for his lever” “I used tart. ant. at the commencement of my practice and succeeded with it as well as I could wish I therefore contained it, but only in the early stages & to produce a powerful orgasm. If it acts upon the stomach only it aggravates the disease Other practitioners rely upon different articles & probably with equal success bearing in mind however that a powerful impression must be made Decoct. sang. to prostration & vomiting seneca or lobelia inflam with the same view” “Sulph. copper & zinc & acetate copper useful to assist in the latter stages or when other emetics are worn our. So also hives syrup which is much used at the south.” “For six or 8 years past croup has been occasionally different from the pure inflammatory. It affects the lungs and duodenum& calomel and cathartics are the remedies to overcome this form. The cough is more frequent and loose the paroxysms less distinct there is pain in the epigastrium vomiting & a membrane is formed in the duodenum which passes off. I have called it angina duodenitis. The same year ulcerated sore throat came on with it the slough leathery & like a burn it seems to be intermediate between A. tonsillaris & A. maligna The application of lunar caustic by a pencil or brush would prevent croup Blisters to the throat & chin were useful yet a blister would produce the same action as existed in the throat, forming an ulcer very difficult to heal Slough ¼ in. deep 3 mo. in healing. In one case the blister cured the croup and the ulcer killed the patient It is desirable to translate action to parts less essential to life. Cal. & carth. would translate it to the duodenum Emetics & powerful treatment do hurt here. The vapour bark is good. “Croup sometimes recurs several nights in succession A. Laryngea is more apt to do so” “When crop assumes a chronic form emetics irritate inhalation of vapour blisters opium diaphoretics & expectorants” “In chronic croup the inflammation in erythematic and not membranific. The vapour bark often does wonders Tartrate of sanguinaria in ¼ gr. doses Tinct. hyoscyamus gtts x N.B. Dr Woodwd treat of subacute ([S?bertonic]) & typhoid croup the latter contraindicating tart. em. & requiring sanguin. turp. mer. calom. etc. & sometimes capsicum, ammonia & even perhaps wine & alcohol. “One of the most extraordinary examples on record however of the effect of disease in developing of perceiving a certain class of relations is that of [Zerab] Colburn His history is well known When quite a child in his sixth year, without any previous instruction, he could by mere intuition perceive the relations of numbers with so much readiness and precision, as to solve almost without reflection questions in arithmetic which would require a long calculation to enable others to answer. How he obtained this result he could not tell. The answer seemed to present itself to his mind with the same readiness and conviction of its truth, that the proposition tow and two make four does to us. These facts I saw are well known, but it is not so well known, that this power was the effect of disease. That such was the case I have very little doubt This was the opinion of a very distinguished physician who saw him at the time, and who ascertained that he was then affected with a peculiar nervous disease the same (chorea) which Jane had a few years since. In conversing with Mr Colburn about a year ago I asked him if he retained the power of calculation which he possessed in his childhood. He said no, and attributed the loss to the want of its exercise. But why should exercise sustain a faculty in existence which was spontaneously developed?” “Account of Jane C. Rider the Springfield somnambulist; by S W Belden MD. Springfield 1834” p. 108 “The discovery of Zerah’s power of calculation was purely accidental Zerah not having yet completed his sixth year was overheard by his father, as he repeated to himself in his play, parts of the multiplication table. The father surprised proceeded to examine him & [found] etc. 1 Diseases of children [B illegible 31] Proposed plan name – history symptoms & causes [Regar] plan of treatment minutely described Other modes of treatment Miscellaneous remedies N.B. Collect all his remarks on art of practising medicine Contents page Introduction Tumour of the head from difficult parturition 5 Cutting the frenum linguae 5 Congenital hydrocele 5 Management of children – as to Particular appetites – Preventive medicine 5 General nature of the diseases of children 6 General operation of remedies in children Diseases within the month Retention of the meconium 8 Jaundice 11 Acidity, Flatulence, Hiccough etc. 12 mothers milk & cows milk 12 Costiveness & its consequences 12:a Vomiting 12:d Diarrhoea 12:f Prolapsus ani 12:l. Aphthae 13 Eruptions in general 19 Strophilus interlinctus or Red gum 19 Strophilus candidus 21 Crusta Sactea 22 Eruptions of Dentition 24 Eruption resembling the itch 24 Venereal Eruptions 25 Infantile Erysipelas (Rose rash) 27 Sore ears (Intertrigo) 30 Tinea capitis [???phlicus]- [illegible] [illegible] on [illegible] [1821-2] 32 Dentition 34 Cholera Infantum 40 Infantile Remittent 55 Mesenteric Fever 61 Tympanitis 66 Worms 69 Volvulus 86 Nervous Rheumatism Infantile [remedy] 89:a. Convulsions 90 Epilepsy 96 Catalepsy 99 Chorea 100 Ulcerated mouth 103:a. Gangrene of the mouth 104 Parotitis or mumps 112 Tonsillitis or Quinsy 115 Rosalia or Scarlet fever 120 Croup or Bronchitis 132 Laryngitis 139 Epidemic catarrh resembling croup 141 Whooping cough or Pertussis 144 Rickets 158 Scrofula 162 Mesenteric fever Hydrocephalus 164 Chilblains 176 Painful aff. from cold without discoloration 177 Burns 177 The cause either is to be found in [???uctural] [illegible] for the [illegible] This will [illegible] men to trust their lives to unknown men, or to fictitious names in the newspapers, where they would not trust property even to a small amount # Formerly prescription of an experienced physician very often set aside for that of the nurse or a negro woman 1 Diseases of children 1 In this part of our course I direct your attention to the history of man in relation to his habits, diseases, & their remedies in his infant state That this subject has occupied the attention of the learned less than any other branch of the medical profession, is universally acknowledged 2 – It is unnecessary for me to enforce the importance of the subject, by any remarks which might be made concerning the evil to society from a neglect of a part of the practice in which the community is so deeply interested 3 – I need but advert to the evils which must result from the practice of committing the management of the diseases of infants to a class in society which is the lowest in point of intelligence 6* [the opinion of the nurse is sometimes taken in opposition to that of the physician – On this subject the world seems to desert its principles of reasoning on other subjects. If a point of law is to be decided men will not trust to a petty of the court, in preference to that of an experienced If a text of scripture is to be explained, men apply to a learned divine in preference to the mere servant of the church & on the subject of wearing apparel it prefers the opinion of the master to that of the apprentice.] 4 – That this subject has occupied the attention of the learned less than any other branch of our profession is universally acknowledged. (The French & Germans however, have neglected it less than the English; and the American physicians have been in the habit of paying more attention to diseases of children than the Europeans) 8 Great attention has been paid to diseases of children within the last 30 or 40 years It has been most neglected in Europe, but less by the French & Germans than by the English 17 European practice differs from ours – but less so at present than formerly because the constitution of our countrymen are coming to resemble those of Europeans 12 It is also the case that European diseases differ from ours on account Disease, here is [illegible] more violent owing probably to the greater of climate etc. Angina [Trachealis] is much milder with them & requires much milder treatment # vicissitudes of the weather 2 5 - The causes which have excluded physicians from the treatment of [infantile] diseases infants, having ceased to exist the subject is now receiving the attention which its importance demands 6 – These causes may be enumerated in few words – viz. the exclusion of the faculty from the practice of midwifery – from the difficulty of obtaining correct ideas upon the subject from its obscurity – the prejudices of the public on this subject – attributing as they do intuitive skill to nurses and matrons * vid. page [illegible] & perhaps also the indifference of the profession 7 – At the present period, however, the enlightened physician watches the mother during the whole period of gestation, receives the child upon its first introduction to the light, & prescribes for its diseases from infancy to old age 9 – As knowledge however must on this subject, as on every other, be progressive, it follows that this part of the profession having but recently received the attention of physicians, has not attained the perfection of the other branches 10 – American physicians need American treatises on this as on other medical subjectds 13 – European practice, as exhibited in their works, is too slow and mild to meet and overcome the morbid excitement of acute diseases in our climate. [Chronic diseases may be treated They practice no deceit 3 with mild remedies, but acute diseases are made worse by remedies if those remedies are not sufficient to overcome the disease The action of the remedy falls in with the diseased action and aggravates all the symptoms if it is not powerful enough to overcome the diseased action IN such cases disease is to be taken out of the hands of nature. The powerful [enemy] is not to be irritated unless there is a prospect of overcoming him] 14 – The difficulty of acquiring a knowledge of the seat of the diseases of children, on account of their being unable to communicate their sensations by language, has been made an excuse by some physicians for neglecting the subject of infantile diseases We may remark however that the difficulty of attaining a correct knowledge of a subject, cannot be given as a reason why it should not be committed to men of intellect & science 15 – Though children cannot communicate their sensations by language, yet the other symptoms by which we determine the seat of their diseases are more uniform in their appearance & more certain in their indications than those of adults 16 Children are under no restraint from feeling fear, [delicacy] or from false modesty In the infant, the mind does not react upon the stomach & destroy its function When Dr Harris published his essay on the acute diseases of children Sydenham said to him “you are the first man I ever envied and it is my firm belief that your little book will be more useful to mankind than # Adult patients also will often deny the existence of dangerous symptoms; for fear they shall be considered as very sick The subject has not yet been thoroughly investigated. No regular course on it has been [illegible] until quite recently in [illegible] of the European schools. I recollect the embarrassment under which I laboured under at the commencement of my practice Cases frequently occurred which were not described in any of the books [&] I was obliged to acquire all my knowledge on the subject from older physicians or from experience. My students have often expressed to me the satisfaction they experience from an examination of my notes and they have often quieted the anxieties of parents by reading extracts from them # In my embarrassment upon being first called to a sick child though familiar with the treatment of adults & having attended the first schools in the country I found my information & in books as to [illegible] nature or treatment and was obliged to have recourse to the older physicians 29 [Dewers] is popular addressed to mothers, very prolix & not intended for a text book but perhaps able [work] & is the 30 [illegible] # Parents think a young physician will do well enough for a young children and are much more apt to call one in for such patients 4 mind does not react upon the stomach & destroy its function We are at no loss how much to attribute to disease & how much to [illegible] # 17 – Still with all these advantages & notwithstanding the importance of the subject it has been neglected & has received less attention than any other branch 18 – When Dr Harris published his essay on the acute diseases of children Sydenham said to him, you are the first man I ever envied, and it is my firm belief that your little book will be more useful to mankind all I have written” This opinion was not founded upon the merits of the book but upon the fact that the attention of physicians would be drawn to this part of their profession, not the least useful though the most neglected 25 Authors on this subject & their merits 26 Underwood Still the department has received less attention than any other branches of our profession 27 Dr Rush in his works, has many remarks 28 Periodicals contain more or less upon the subject 21 – No courses in any of the schools 19 – Some physicians of the first respectability have acknowledged their ignorance & given up to nurses 20 – I recollect the embarrassment I suffered upon this subject # It is a common complaint 22 Since I have lectured upon this subject, our students at parting have expressed their satisfaction. 23 Young physicians are first called to children because the older ones neglect them # hence its importance to them 24 Parents however seem, as a matter of fact, to prefer a young physician, for a young patient! # 34 – I shall first remark upon a few surgical cases which occur to the young physician soon after the birth of the child [illegible] cutting the frenum. I have never seen a case in which this operation was necessary. It is very common for nurses to insist that children are tongue tied. Dr [Eneas Munser] was called in such circumstances he remonstrated the nurse was instant until finally he drew the back of a knife across the frenum & the child he told [illegible] [illegible] hurting and this with this [result] was relieved to the great satisfaction of the nurse. If there is a false frenum it may be divided.” this [illegible] [frenum] is never so short as to confine the tongue & cutting it is a dangerous operation # They will tell you that this particular appetite is indicated by the natural crying of the child The mother will set herself to recollect some former longing of her own [illegible] 6 Hydrocele Young physicians are often called on to prescribe for congenital hydrocele in young children The complaint is apt to excite alarm but neither troublesome nor dangerous. It is readily distinguished from [illegible] by its transparency, insensibility, & not yielding to pressure. In the course of my practice I have had to operate in but one case in children. Dr [Dewers] recommends pouring considerable quantities of cold water on the part. I myself have frequently cured it by washing the part with cold water in the morning and applying camphorated spts in the course of the day. You [illegible] direct the application of spirt & water, camphorated spirits, [muria??] of ammonia, [opium], spirits of nitre, in short every discutient Or you may direct astringent lotion, as a strong decoction of maple bark, spriaea Fomentosa Geranum, Rhei etc. Case in which I had to operate year old probably neglected 2 or 3 inches long about as large as a small egg. Operate without a cannula - with a lancet & catheter & injecting syringe – water 1/6 or 1/8 port wine – children more irritable - vomiting 5 Tumor on the head 35 Children are sometimes born with a tumour on the head occasioned by difficult labour This may be distinguished from a tumor caused by a deficiency in the bones of the cranium, by a uniform hardness. “We may apply mur. amm. or spt & water” 36 – Cutting the Frenum 37. Hydrocele 31 Management Appetites 32 A prejudice prevails in some classes of society with respect to a point in the management of children Some children are thought to be born with a strong appetite for some particular kind of food, which was possessed by the mother previous to the birth of the child & inherited from her. It is thought that the child will [pine] & ultimately die, if this [illegible] appetite be not gratified # It is probable that a belief in this doctrine has caused many children to be killed by the administration of improper food A fact of this kind occurred in Humphreysville, which nearly proved fatal to the child. Vide next page Preventive medicine 33 As a general rule medicine is not to be given to children in health for fear they should be sick. Some are nursed to death, while some die for want of nursing. Some are fed to death while others are starved Some are physicked to death while others die for want of medication injection immediately with [draw] healed [illegible] with swelling The child cried much # - a council of females was called who set themselves to make out what the child needed Finally the mince pie was concluded to be the article the child sucked down the inside & the report was that this effected a cure & saved the life of the infant. Prof. I inquired of the attending physician who informed him that the child was indeed alive and well at present but that it was made very 8ll by the mince pie & came near losing its life. The crying of the child in this case was probably nothing more than a trifling increase of the ordinary crying of very young infants, which is a natural and wholesome exercise # The al. can is large in proportion to the [illegible] of the whole system # The above is a good example of the various prejudices which have prevailed among [nurses] respecting the management of children. Owing to the influence of enlightened physicians these are no disappearing. (examples to be given) 6 38 – Diseases requiring medical treatment General considerations 39 – In investigating the causes and seat of the diseases in infants the mucous membranes claim particular attention 40 The action of this membrane is greater in the infant than in the adult constitution Its secretions are often morbidly increased & are sometimes diminished. It is subject to spasmodic action and to inflammation [illegible] with [illegible] or decomposed with effusion of coagulable lymph. “It is subject to turpidity & to spasmodic action which by sympathy extend to the whole system 41 The liver is much larger in proportion to the body the infants than in adults “& its secretions are much of [illegible] as to quality & quantity than in adults” 42 The secretions are much concerned in their diseases. They are changed as to quantity and quality # Prescott child no ducts lived 3 or 4 months and was excessively emaciated – there was no bile in the stools There was no [previous] duct for the gall bladder into the disorder # There is greater susceptibility to action & tendency to conversion # Just as emetics are given to a stomach [complaint] from excessive quantity of food 7 42 The nervous system of infants is more easily excited, and more affected by the various causes of irritation such as dentition worms acrid substances in the first primae via passages etc. 43 – The blood vessels are more rarely the seat o f disease in infants than in adults – particularly, primarily so much as irritative [acid] if they were affected the action is not [illegible] 44 – Consequently their fevers are fevers of irritation, rarely enteric or those of inflammation 45 Operation of medicines Children bear evacuation better than adults witness the long continued diarrhoea without much debility following, or the salivation for mouths during dentition without a waste of vital energy In operating upon the abdominal viscera it should be [illegible] it is not for the purpose of mere evacuation, it is to produce an excitement for the purpose of overcoming a morbid excitement also to produce healthy excitement a case of torpor # The milder purgatives should be used, the drastic being irritative. Emetics Bleeding Do not bear narcotics vide p. 11 2 – In general the evacuation of the meconium should be effected by the [colostrium] or first milk of the mother which has a laxative property # The child should be put to the breast within 2 or 3 hours from birth # unless [illegible] Instead of suffering the nurse to feed the child for the first 2 or 3 days the breast should soon be presented for if the child feeds it is in danger of losing the instinct to suck If the [colostrium] does not bring away the meconium we may begin with soda as mentioned below or with cold sweetened water Some give a little cold water at first vide [infra] 5 – In strong children cold bathing may be employed with advantage, but the bath should be made tepid for weak ones & gradually used colder as the child can bear it # “If from the exhaustion of parturition the mother be unable to suckle let the nurse commence feeding at the end of 3 hours” vide infra Give a grain of carborate of soda in a teaspoonful of water until iii qts [have] given # The meconium is frequently evacuated during parturition. After birth also the al. canal is set in notion by the crying and mother of the child and the stimulus of the air upon it vide p. 10 skin. # Colostrium is of a yellowish colour probably contains bile & is cathartic # It was formerly supposed that the child should not suck at first. The consequence often was that the child lost the interest to suck 8 Retention of Meconium 1 – The first diseases of infants which claim the attention of the physician are those which arise from retention of the meconium. The meconium is a matter always existing in the bowels at birth & having a dark green colour when evacuated. It resembles tea but is more mucilaginous # It will ordinarily be sufficient to give a little molasses and water to the child until it receives the [illegible] or first milk from the mother which has a laxative quality 6 – If it is suffered to remain a train of diseases may follow. In the diseases which occur within the first moth after birth the retention of the meconium is always to be suspected as the cause 7 – The diseases caused by retention of the meconium are Severe paroxysms of pain in the bowels indicated by crying & writhing – Tumefaction of the bowels. Convulsions. Epileptic fits. Trismus nascertium or Locked Jaw This last disease is very common in some of the West Indian islands, but I have never seen it in this place 8 – Whatever disease may arise from retention of the meconium the principal indication will be to remove the irritation by evacuating the bowels. This is effected by cathartics. A teaspoonful of castor oil is generally sufficient. If [illegible] necessary 1st indic to remove meconium 2nd obviate effects # IT will be sufficient to pour on boiling water instead of boiling the materials in the water The strength however is of little consequence Sometimes the most powerful remedies are to be used beginning with mild. These used full doses of calomel, scammony 2 to 4 yrs – [illegible] assisted by injection, & warm bath until the bowels were moved Wait how long for the operation of each? # By emollient injection, irritation is allayed, and if the lower part of the bowels is excited the rest will be Dose 2 to 6 pills each pill containing 1 gr. of (calomel) # Chalk & calomel is a substitute for blue pill – perhaps the chalk qualifies the cal & at least it corrects acidity Antimony should scarcely ever given to children within the mouth # A great part of the calomel has no effect [illegible] it does not come in contact with the coats covered with mucus In cases where there was great quantities of [mucus] I have given full doses of cal. 9 the dose may be repeated every 4th or 5 hours until half an ounce has been given 8 – If the oil is rejected from the stomach Senna & Manna may be given – zi of the former to zss of the latter boiled in gill of water # & administered freely until the bowels are moved once in ¼ or ½ hour “ Rx Sennae zi [illegible] ferv. 1 gill 1 or 2 teaspf every ½ hour” 9 – The operation of the cathartic should be assisted by emollient injection # 10 – Fomentations to the bowels will assist the operation of cathartics & if spasms exist, will always be needed for their relief 11 Cathartics of various kinds 12 The best cathartic which I have used for infants within the first month after birth is the blue pill (or [mellated] pill It rarely offends the stomach and never produces griping By it the action of the liver & the secretions from the mucous membrane of the intestines are excited more than by any other cathartic except perhaps calomel. In my practice I have never known an infant salivated by it. # 13 In severe cases where the blue pill is insufficient we must have recourse to calomel, which may be given in doses of from two to 10 grains. It is often necessary to give as large doses of calomel to children as to adults owing to the great quantity of mucus in the intestines by which they are defended from its action. # The meconium scammony or jalap as a laxative & had them operate mildly If the cots were [naked] [illegible] a dose would prove fatal for irritation # This is a mild cathartic and supposed to act chemically. # “Evaporate the [illegible] over the fire stirring it until thick then add chalk till it is of a consistence suitable for pilling Each pill may contain 1 or 2 gr. of Dose from 2 to 5 gr. Or it may be dissolved in herb Fish, gall has been recommended [illegible] gall Rattlesnake has been thought to have specific properties especially in fevers. This article is bitter, tonic [illegible], laxative, & [illegible] Continued from page 8 “The infant may be put to the breast in one or tow hours from birth This course will produce permanent contraction of the [uterus] & tend to stop [hemorrhage] & prevent milk fever” When an infant is first born it is well to wet its mouth with half a teaspoonful of coldwater and give it nothing else until it is applied to the breat 10 while retained will likewise prevent the operation of the remedy by involving it in its viscid substance 14 Chalk & calomel may be used in doses of 1 gr. cal. to 4 or 5 chalk repeated once in 2 or 3 hours 15 Other cathartics which may be used are or as recommended by Dewers 1 gr. carb. sod. to a teaspoonful of water repeated every “it operates” 15 minutes until 10 gr have been given. # Decoction of the flowers of the dandelion & the mullein Senna 2 dr. to with 4 dr. of aromatic herbs or seeds The bile of animals (ox gall) is a good cathartic Perhaps we may consider it as acting as a substitute for the childs own bile. It may be given in [catnap] tea milk etc. # 16 An injection of bitter or 16 aromatic herbs will allways assist the operation of whatever cathartic you use & in mild cases frequently will be sufficient of themselves – superceding the necessity of giving anything by the mouth Continued from p. 8 The stimulus of sound upon the child, crying, irritation of the air upon the skin, and especially muscular motion, excites the peristaltic motion of the child. The influence of muscular motion upon the peristaltic action of the bowels, is considerable, as is seen in horses while travelling, the costiveness of sedentary persons etc. “The warm bath at the temperature of 98 or 100 assists the operation of cathartics renders their action more mild equalises the action of the system and nervous irritation It is especially useful when convulsions are present and may be used at any period except in cases of extreme exhaustion” # It is the most powerful antispasmodic for children [have] acting upon the extremities of so many nerves Jaundice “Jaundice sometimes appears at birth indicated by the yellow colour of the countenance and arising from obstruction of the liver etc. Such cases are generally incurable. The first remedies are the mild deobstructant plant, small doses of calomel etc.” 11 When convulsions are present the warm bath should be used to assist the operation of whatever cathartic is used, to render the operation mor mild, to equalise excitement and to remove irritation. This remedy may be safely used at any period after birth # After the cause which excited the convulsions has been removed, if the morbid irritation of the nerves continues, the bath will again be serviceable 18 Antispasmodics may likewise be used such as valerian, aqua ammoniae, elix. asth. artificial musk infusions of catnip etc. We may use aqua amm. 3 or 4 drops or carb. amm 3 or 4 gr. or asafoetida a teaspoonful of the tinct. in milk & water, or camphor by enema Be [cautious] of giving narcotics to children Some are more susceptible than others. And some children are accustomed to [them] from birth. Case of a mother who had inured a child of 3 m. to bear 30 dr. of SS. I proposed to give paregoric, beginning with 8 or 10 drops, and found that the child had often taken with impunity 31 dr. of SS. to produce sleep 4 – “Child bed women are generally to be treated with mild diet for the first week after delivery, unless their strength has been much reduced by parturition, when they may take port wine in moderate doses” # “If light stools indicate a deficiency of bile the administration of oxgall will be found very serviceable vide [illegible] If acidity is produced, add limewater, If diarrhoea is produced, use arrow root instead of the water, or any other [fecula] Children are apt to receive too much food; hence cow’s milk should be diluted with water. Milk may sometimes coagulate in the stomach of children, in large quantities and occasion much uneasiness Meat should not be given under 6 mo. unless in particular cases which are exceptions to the general rule, where milk disagrees or perhaps in the case of some scrofulous children 12 Acidity Flatulence Hiccough 1 – Very young children are often troubled with acidity, flatulence & hiccough These affections may be removed by a free use of magnesia, lime water, or aqua ammoniae 2 – It will not always be sufficient safe? to administer these articles to the child alone. The mother or nurse must often take them likewise 3 – Sometimes the mothers milk disagrees with the child. This will be known by the constant disorder of the bowels of the child. by the evacuation and pain suffering after nursing both child and [illegible] mother may seem to suffer without a cause The stools may be slimy# The child may cry obstinately 5 – If the mother’s milk continues to disagree we may use cow’s milk diluted with one third or one half water & “sweetened” or with arrow root mixed first with a table spoonful of cold & then with one of hot water, in order to make a homogeneous mixture 6 – Children fed on cow’s milk are more apt to be costive. To prevent this give a little magnesia, decoct. of dandelion etc. Peach tree blossoms are much used, but are too violent in their operation The injection will start the machine again The injection may be made of Eupatorium, catnep, elderflowers mallows etc. etc. Apply first whatever can be first prepared counterirritants for instance. Spirit or mustard to the fat ammonia etc. ammonia to the mouth and nostrils etc. endeavouring to rouse the patient 4 – [A young physician should be careful to know what to do in sudden cases (much depends on a favorable impression at first) Neighbors and friends usually assemble around a child and the expect the physician will be able to prescribe at the moment. In such cases set some of the bystanders to preparing a warm or tepid bath – no matter if eventually if it should not be used. Set others to preparing some other thing and so on. Thus while the attendants are all employed he will be able to devise some course to pursue] I recollect an old physician in this situation who was pressed what to do & replied “stop let us think about it” 12:a. Costiveness & its consequences 1 – Physicians are frequently called upon to prescribe for infants who are in health except that they are costive Children fed from a spoon or bottle are mor to be thus affected than those who are nourished from the breast. If costiveness is produced by improper quantity or quality of the food as is sometimes the case, the diet must be changed 2 – Costiveness if not attended to in time produces flatulence, watchfulness, startings, hiccough, diarrhoea vomiting & convulsions 3 – A physician is frequently called to children I fits, who have been apparently well until the convulsions come on The safest and most efficacious prescription that can be made, is an injection & indeed is all the treatment that most cases will require. Let a warm bath be immediately prepared & the patient put in it if the enema does not relieve. While the convulsions continue the mouth is closed & we can operate on the system mainly by the rectum & the skin 5 Be careful to make your directions for administering an enema very definite, unless you know that the family are familiar with injections Case of a mason’s man hands & knees shooting somewhat off fright rolling over murder The enema may consist of simple warm water, or milk & water, or of tea of thoroughwort or catnep etc. a table spoonful of salt may be added finally castor or other oils may be thrown up in extreme cases the rectum has been filled with lard The water for the tepid 12:b. bath should be about blood warm. Be careful to bathe the child, & not merely to scatter or sprinkle water on it. The length of time during which the child may be kept in the bath may be from 5 to 20 min. While the patient is in the bath if it is sufficiently relieved to be capable of swallowing give a dose of calomel for a child of 6 months 6, 8 or even 10 gr. If improper food is the cause 20 gr. are not dangerous, for infants will bear full doses of cathartics though very small ones of narcotics In bad cases of convulsions the means to which we have it in our power to resort, are external irritants such as garlic draughts to the feet, injections of [nervines] the most powerful of which will be a teaspoonful of tinct. camphor thrown up in a gill of milk & water & the warm bath until we can administer articles by the mouth “If the child be feeble & exhausted upon coming out of the bath give cordials or tonics” Any quantity of food in the stomach & bowels which is not congenial, interrupts the process of digestion & the peristaltic motion functions whose importance is second on ly to that of respiration. When these functions are interrupted the muscles are brought into convulsive action to relieve the system Be particular in your enquiries about food for those who have the care of children are very careless and children will swallow whatever is put into the mouth. I recollect being called to see a very strange worm which a child had voided. The imagination of the attending physician & parent were excited. To me whose imagination was cooler the worm appeared to be a piece of bark I enquired if the child had had no slippery elm bark & found that it had been chewing some. Then the supposed worm was accounted for Rye flour is more apt to become acid than oatmeal # Cal. sometimes by its irritation produces convulsions I have known a family, all the children of which were thrown into convulsion by cal. & I was obliged to be very cautious & use blue pill injections etc. There are several milk remedies such as dandelion which is tonic laxative, & deobstrument acting on the liver, mullein fl. elder [blo??] tea “The pollens of most plants has a laxative quality” I have seen no danger from the prussic acid of the [illegible] flower & it is much used [illegible] from [illegible] also among the French they hold a place the French Pharm. Wild liquorice [gal??] [Circa???] resemble the dandelion Moderate friction excites the bowels Sometimes alkalie or chalk, though generally they are rather constipating, prove laxative probably on account of the acid combining 12:c. II II Where is a tendency to costiveness, the use of oatmeal gruel or porridge will be beneficial or a porridge made of wheat flour with the bran, strained through a cloth & mixed with the milk with which the child is fed also rye meal gruel or rye bran gruel If the health is not affected by the constipation be cautious about giving much medicine. It is always better to cure this affection by food than by medicine. # Castor oil from a teaspoonful to a table spoonful is the best cathartic magnesia given with the milk is a good remedy but not always sufficient. Elixir salutis is one of the most common family medicines. This article with castile soap dissolved in it has been found very serviceable. The gall of animals may be recommended. The blue pill operates gently as a cathartic & is useful in changing the habitual disposition to costiveness. I have prescribed with advantage decoction of the flowers of the dandelion, or mullein. The flowers of the peach tree are much used for the same purpose but “are rather too powerful for ordinary cases” “They are powerful even for adults” & sometimes gripe unless combined with aromatics Calomel may be used with safety # “In severe cases mustard and ginger may be applied to the abdomen” Mechanical manes in the form of suppositories are much used by nurses such as a piece of molasses candy or a roll of paper moistened with oil. They are beneficial. # If the child has been weaned pay particular attention to its food. Nurses are very careless. # “No serious evil will arise unless young & anxious mothers should give medicines and thus make the child sick” “If vomiting arises from dentition we must remove the irritation Give laxatives, as magnesia, & narcotic Children should be early accustomed to the reception of enemata to prevent subsequent prejudices upon the subject. I recollect the case of a child about 12 who was suffering from an obstinate constipation caused by an affection of the lower spinal nerves which produced a partial paralysis of the rectum and bladder so that a catheter had to be introduced & injections were [illegible] demanded. But all the efforts of the nurses (women) were unable to administer an enema Calomel had been given until the mouth was affected, yet without producing an evacuation. Finally the patient went into an insensible state, and injections were given & produced free evacuation. I have heard adults say they would die before submitting to receive an enema. 12:d. Vomiting Spontaneous vomiting in infants arises from over distention of the stomach. The discharge is made without nausea & almost without effort, & consists of pure milk or milk coagulated. The mother should simply be cautioned not to allow the child to nurse so long at a time. # Children and old people vomit with more facility than the middle aged If vomiting arises from the sympathy of the stomach with some other part of the system which is in a morbid state, the primary disease must be first cured & used for the irr. of stom. For the vomiting itself in palliative we may prescribe lime water & milk. a teaspoonful of each; soda water, or any liquid affording an abundance of carbonic acid. Vomiting from irritability of the stomach or free [illegible] requires particular attention. The attendant symptoms will be paleness of the countenance, quick & feeble pulse, & cold extremities. Irritants must be applied over the region of the stomach. They may consist of ginger, mustard, horseradish leaves, mint etc. aqu. amm. [illegible] essent oil dissolved in alcohol” The alkalies such as pearl ash, also soda water “lime water” may be given internally. Excite a discharge from the bowels by injection or a calomel cathartic to remedy the irritated action of the stomach “[illegible] counterirritation” The warm bath will be very serviceable, soothing the nerves of the skin & by sympathy producing the same effect upon those of the stomach nervines also may be given We may try putting a little brandy into the mouth or a small quantity of capsicum tea. Hot cloths & fomentations may also be applied externally. A large bulk of warm water water may be thrown up the rectum in obstinate cases, use stimulating injections.. One of the most convenient modes of administering a large injection is by a pipe fastened to a large ox bladder Press the fingers against the end of the pipe which the bladder is fastened so as to make a valve and prevent the escape of the fluid contained in the bladder, until after the pipe has been completely introduced into the rectum # I used to carry this recipe about me when I practiced in the country Frequently irr. of stom. is overcome by irr. o f the rectum by an enema of salt & water or by a large injection to produce a peristaltic motion downwards 12:e. Ren “Remove the cause, which is frequently indigestion. If it proceeds from the teeth, lance the gums The following is an excellent recipe # in these cases Rx Cret. ppt zii sem. card. zi bi carb. potas. zfs grind aqua bullientis 0 fs Give a tablespoonful every half hour I am inclined to the opinion that the alkalis, such as pearlast act by creating an excitability Emetics are particularly safe for children much more so than for adults. Ipecac is generally the best unless the disease in which the emetic is indicated is very threatening, when antimony should be used Squills are indicated in emetic doses in complaints of the chest “with [illegible] [illegible] but should not be administered when there is much inflammatory action in the system. “Warwick’s powder a preparation of antimony, was once popular and often administered without the advice of a physician. I have known it endanger life Nurses should never prescribe antimony” Some situations are more liable – low situations [seashore] Children shut up in low dark apartments suffer from want of amusement. If a diarrhoea from teething is suddenly stopped the brain is apt to be affected. This affection of the brain is peculiarly liable to occur in children. There is no outlet to the brain 12:f. Diarrhoea This complaint sometimes affects children for months & even years Some families are more subject to it than others & I have known those in which all the children would be affected with diarrhoea from a period soon after birth until they were three or foru years old. The children who have this predisposition to the disease are born with diseased liver and bowels & have indeed all the chylopoietic viscera in a disordered condition. Hence among the causes of diarrhoea we may rank a bad constitution. Other causes are want of cleanliness, bad food “want of sufficient clothing” bad air damp rooms, confinement & want of exercise. Exposure to cold & moisture A bad air probably causes diarrhoea mainly by its depressing influence. The effect of confinement and want of exercise is very great. Young animals suffer in the same way Even vegetables seem to need motion for I think I have observed a great deficiency of fruit & a sickly appearance of fruit trees after a season uncommonly free from wind. Confinement is injurious in another manner Children need mental stimulus from a variety of external objects. I have known surprising cures effected apparently by the operation of this very principle. Teething is a frequent cause & whenever it is we must palliate & check, but may not stop the diarrhoea From the sudden stoppage of a diarrhoea during dentition you may expect an affection of the brain to follow. The discharge from the bowels in this case is similar to that of tears from an irritated This will be convenient in many cases as in travelling Other mints may be used spearmint is most agreeable I have given this in the latter stages of the diarrhoea of adults with advantage Almost any cath. will often check a diarrh. Cal or blue pill is generally best Judgment is to be exercised whether to prescribe an emetic or a cathartic & as to the choice of a catheter Ipecac however is almost always safe children bear emetics well Put the parents & the nurse upon investigating as to [diet] Persons are apt to very careless about giving things to children And they may have wrong notions as to particular articles Prohibit solid oily food, crude vegetables and esculent roots. Potatoes are very bad in diarrhoea so are the analogous roots. They contain indeed much fecula, but also much 12:g. eye, or of mucus from the lungs The expressed juice of mentha vulgaris, boiled skimmed and mixed with white sugar is an agreeable, & useful article for the cure of a diarrhoea, which has continued but a short time & is not severe. In the early stages of a diarrhoea, which is sufficiently severe to demand the attention of a physician it will generally be best to commence the treatment with a cathartic; though if fever accompanies it an emetic of ipecacuanha should be the first article administered. Judgement must be exercised in the choice of a cathartic. Calomel will be best if the child be not particularly feeble or of a very delicate constitution & for a feeble child the blue poll. I myself was for formerly many years unable to take any other cathartic than the blue pill without being griped. Generally it will be best to combine chalk with the calomel, as the latter is indicated for its deobstruent, rather than for its purgative effect. The dose may be about 2 gr. cal. with 5 or 6 of chalk If improper diet is the cause the food must be changed; & it will generally be necessary to be particular in our enquiries with regard to the diet for the parents may consider many things a safe which would be strictly forbidden by the physician. Especially will it be necessary to attend to the diet if the child feeds instead of sucking. Every thing hard of digestion, such as salted & oil food should be prohibited The diet should be arrow root and in case of diarrhoea this article will be improved if prepared with a little laudanum or wine sago taipica, which is probably a hydrate of besides They are apt to become acids & acrid in the bowels. In the Polyn. islands The inhabitants living upon taro are very liable to diarrh. West of the Rocky Mts Lewis & Clark found the inhab. subject to diarrhoea for living on a root [illegible] [illegible] men suffered in the same way after they arrived among them In the evacuations & the evacuations of children shd always be exam [may] [illegible] that potatoes remain undigested Cullen & Rush thought different of potatoes The evac. of chil. should always be [illegible] Pies cakes articles containing much sugar hot bread should be prohibited Bread shd be toasted The juice of meat will often be beneficial No gravy (i.e. artificial or carbonized fat with flour etc.) Potatoe starch, pure, is perhaps not inferior to the tapioca etc. Boiled flour becomes s hard as stone almost hydrate It is an old practice It is an excellent preparation make a porrige of it grated Tapioca I suppose is made by sprinkling casserva root, powdered, with water & baking it making a preparation what appears like gum arabic. I have not been able to learn how it is made, but have made it this way a similar substance of arrow root Arrow root & the tapioca are cooked by first dissolving them with a small quantity of cold water & then adding hot water. In this way [illegible] are avoided 12:h. flour or roasted or baked flour made into a porridge with equal parts of milk and lime water. The bread should be toasted and butter should be used very sparingly gravy not at all. Casserva sago etc. An article similar to tapioca, if not the same may be made in the following manner. Tie up a quantity of wheat flour tightly in a clean cloth & boil it for 5 or 6 hours The result will be a hard substance which is to be grated & “[illegible] milk & water or with lime water” made into a porridge this will be palatable & good Rice in gruel, or thoroughly cooked by boiling The worst cases of diarrhoea are attended with feeble pulse, cold extremities, dry skin, & generally a rise of fever once or twice in the 24 hours. Soften the skin by the tepid bath which is [illegible] etc. and keep up an action on it by flannel unless there is fever & in such cases use also absorbents freely with tonics & aromatics. The chalk julep or white decoction will be as good a preparation as any. Rx Chalk [illegible] zfs to zi pul. cinnam. to zii zii, bum arab zi carb. potas. zi water lb I. boil ½ hour Sometimes [illegible] a similar recipe shd be used” The Europeans add [illegible] use [illegible]” a little laudanum may be added. Of this feed freely, giving say a table spoonful from ½ tab sp. to I once in an hour sometimes. As a tonic the vitriolic or tonic solution of Moseley is inferior to none in such cases Rx zinci sulph ziii alum zi water lbi Give from four to twenty drops. Tonics must sometimes be combined with absorbents Opium is always safe in cases where the bowels have been thoroughly evacuated. It is generally better to combine it with ipecac, which will determine its action to the skin and act as a gentle tonic & laxative The tepid bath is [illegible] as it may be called) relieves the irritation of the bowels through the skin Chalk does not act mechanically or chemically it has a specific action upon the stomach as much as bark Make white decoction in various ways if cinnamon offends use some other spice Sometimes add astringents or [illegible] Tonic sol. sulph [illegible] ziii al. zi Mosely sometimes used al. zii In 3 or 4 gtt it is anti emetic In larger doses it may be emetic & cathartic This is a state of the system similar to the collapse of cholera Asiatica It is a collapse taking place during diarrhoea. I have found advantage from stimulating or acrid injections as salt & water, mustard In chronic diarrhoea opium is often invaluable. Some families are obliged to give it 2 or 3 times a day for along time to their children until they are so old as not to be liable to continual diarrhoea The stools may be green clayey from deficiency of bile sour curdled [illegible] or very fetid, so much so as to be very offensive turning the stomach of the attendants. 12:i. In cases of chronic diarrhoea where there is attending it much sensibility and irritability of the bowels opium combined with diaphoretics cathartics or tonics is an invaluable remedy Sometimes violent symptoms supervene vomiting supervenes & the diarrhoea stops the patients hands & feet grow cold his pulse grows small, & if the most active measures are not take used the patient dies in 24 hours. When this change of symptoms take place we must resort to the most powerful means of exciting counterirritation such as application to the epigastrium of mustard, horse radish leaves ol. monardae punctulae, ol. turpent. etc. Such articles as pimento will be grateful and stimulating given internally We may give calomel, opium & the carbon. acid, and use stimulating injections. “Effervescing mixture with SS. [illegible] appt” Particular attention should be paid to the kind of They may be sour & curdled, or mucousy, [illegible] clay colored, water stools for much may be learned from their inspection. Acid is often formed in the whole alimentary canal, producing sour and curdled stools which will indicate lime water or other absorbents, with aromatics. The acid may arise from fermentation or more probably from secretion Such cases I have often cured by the expressed juice of the spear mint prepared as above mentioned & given freely. When the stools are green white, or clayey, give opium to allay irritation. Ipecac to equalise excitement, & the blue pill as a deobstruent, the latter in small doses so as to move the bowels, but once or twice in the 24 hours. Alkalis are useful as # Noel’s plaister was made of white lead red lead castile soap and olive oil, boiled till the red lead was so far decomposed by the oil that the mixture was of a cream colour It is a smooth plaister and is less stimulating than [illegible] Use soft charcoal by burning cork, which is the popular kind or cedar Dose teaspoonful to a tablespoonful in a convenient liquid Lime water & other alkalies may always be given They may be mixed with the food without [injurious] the taste When the disease has continued long & patient is [illegible] phlegmatic temperament we may bandage the bowels, to give mechanical support [Opium] also will be useful applied externally in this way Adults from the Wt. I. with chronic diarrhoea will look like a mummy Bog water is a very soft water & contains carb. hyd. Astringents [illegible] tinct. vitriol decoct. of oak bark with milk & sugar & spice Bandaging & plaisters Take any adhesive plaster and mix about ½ opium Or soap and opium Acetate of lead is not a new remedy 1 2 or 3 gr a day 1 gr at a time continued as long as the relaxed state of the bowels continues as long as they last lead [cholic] cannot take place for 12:j. are also enemata formed by dissolving castile soap in mallows or catnip tea. If there is much griping with tumefaction of the bowels injections of camomile tea give great relief. In diarrhoea of this kind the following is also a good stimulating & correcting laxative Rx castile soap zi elix. sal. zi dissolve & give it 3 or 4 times a day of teaspoonful or ½ teaspoonful doses. If the stools are fetid give charcoal internally. It will correct the fetor & it sometimes cures the disease. For sour stools vie last paragraph of this lecture During the long continuance of chronic diarrhoea it will of ten be advisable to apply mechanical support to the abdomen. We may apply a plaister of white diachylon [illegible] plaister alone or with opium or of lead and soap & a bandage. In chronic diarrhoea the skin becomes brown, of a dark & dirty appearance, & very dry and husky If the tepid bath does not relieve this symptom, we may apply water from peat swamps, which contains carburetted hydrogen. Vide Duncan’s commentaries In the last stages of diarrhoea we must resort to tonic solution to astringents, absorbents & aromatics we may also use opium with cathartics, emetics & absorbents & If we met with a great craving for salt food it should be gratified. The gratification of such an appetite will prove a stimulus, especially to the mind & consequently the more powerful. We meet with similar cases among adults also. Case of a man who could retain no medicines upon his stomach & finally recovered upon bread & cheese, given at his request In the latter stages also of chronic diarrhoea, acetate of lead the [illegible] [become] very lax and there is generally a prolapsus ani patient being [semiphlegmatic] I saw this article much used in this way when a young man and though expecting bad colic no injury resulted. Prof. Smith was very fond of chocolate [illegible] It sometimes acts like a charm Spiraea may be given in decoction or extract. [illegible][illegible] is not so good being unpleasant having a fishy taste & offending the stomach Ger. mac. & [illegible] [arom.] are pure astringents & unobjectionable on this score. I have prescribed sometimes one, or another, according to convenience of locality where I happened to be The root of typh. latif. is used as food by the aborigines European physicians give [althea] [illegible] which is the true marshmallows Usually when diarrhoea has continued long the kidneys become affected. Mucilage will then prove diuretic probably by their [illegible] affect. The terebinthinates will then be useful. The most common practice in this neighborhood is a decoction of white pine bark especially with a little milk it is called healing to the bowels. There is also nutriment in it for the aborigines, sometimes live on it When mucilages to wear out we may resort to terebinth. The species of [polygnomic] knot grass are 12:k. may be given internally. There will be no danger of the production of colic, by this remedy, for the bowels are too much relaxed. The astringents just mentioned may be various We have at least fifty indigenous vegetables, which may be used given in decoction of milk or water such as the bark of the currant, the raspberry, the various species of oak, of viburnum chocolate of acorns etc. white pine bark in milk etc. the roots of the [illegible] of the [geranium] etc. The viburnum Especially deserving of recommendation are the spiraea tomentosa & cornus circinata. The latter of which equalises excitement Of mucilages we may have occasion to use a variety for irritation for any one article may become worn out & another be more grateful We have typha latifolia, twigs of sassafras, hibiscus, malva bran, flax seed, slippery elm, gum arabic etc. all the mallows, all the [illegible] marshmallows hibiscus palustris called rose of [illegible] in the gardens root is [illegible] [illegible] & sub astringent Sour stools Be particular in forbidding the use of animal food. If there be want of bile, give ox gall, lactescent plants dandelion etc. with mild mercurials; e.g. calomel 2 gr. with 6 gr. chalk. Aromatics also may be combined. Astringents elg. [illegible] speraea cornus & geranium do well. Also the following Rx calc. magn. zfs rhei palm. gr. 8 acaciae zi ol. anisi gtt vi aquae purae zi Give a teaspoonful at a dose. “once in 2 hours” In bowel complaints with griping attended with green or sour stools Rx magn. ust zfs pulv. rhei grs viii pulv. gum ar. zi ess. menth pip. gtts vi water zi dose, teaspoonful Spiraea & cornus used – they are mucilaginous sub astringent & diuretic Articles of a stimulating kind are often needed in the latter stages especially erigeron canadande (colt tail) [illegible] The bitter [illegible] which grows in similar situations (ambrosia [elatio??] is also used as a bitter apparently nervine in diarrhoea Roman wormwood) [Cupron] is acrid, sub astringent & diuretic much used in the middle states improper when there is entonic action case of cholerine cured last summer by this garden young man called etc. chewing the plant etc. The other species of erigeron have similar properties espec. E. phil. Various recipes are given for diarrhoea in children Ex mag. zfs rhei gr. 8 [illegible] zi ess. pep. gtts 6 gum ar. zi The popular remedies are generally absorbent [illegible] mucilaginous astringent etc. Much benefit may often be derived from copious mucilaginous injections mutton broth is the most popular probably other broth (fat meat) would answer still mutton suet is less apt to become rancid. It is thought to be useful also as nourishment I have not though much of this may of nourishing Laudanum may be added Also laudanum & starch injections may be advisable to check the excess of the discharge It will generally be best to begin with about 10 drops of SS. though a teaspoonful may be required vide p. 2 [illegible] 2 12:l. Prolapsis Ani This is a troublesome symptom which sometimes occurs in diarrhoea. The protruded intestine should be immediately replaced. Most writers recommend to do this with a dry cloth, but this will irritate the sphincter ani & make it contract. The smoothest and least irritating article within my knowledge, is the crop of a fowl, or the neck of a bladder, turned inside out & filled with warm water # Afterwards we may apply astringent washes & injections of white oak bark or other similar articles, or of acetate of lead. The latter article may also be given internally in doses of from 1 to 2 grains. It will have a tendency to overcome the relaxation. Astringents are multitudinous & have had a specific [illegible], which proved to be the bark of [?strea] virginica At another time I had a specific sent me which proved to be viburnum sentago all the vib. are astringent Prolapsus ani “The part is relaxed and passes down and is then strangulated by the sphincter. For a permanent cure we must resort to astringents & tonics, but the part must be [illegible] by mechanical means If the intestine is not replaced, [illegible] or suppuration will be the consequence” “Take 1 bladder, cut off the neck, turn it inside out, fill it half full of warm water, and tie up the neck” “This disease was very common at the commencement of my practice but is now rare. The change has arisen in a great degree from the more correct notions respecting the proper management of the mother and child which now prevail. It is possible however that it may appear in [epidemics] and that case we should expect that it would appear for a time and the disappear # It frequently follows other diseases both in children and adults # According to the law of contagious diseases and that it is of no use to prevent it # Heat is a stimulus but too much of it produces a debility which may be [illegible] perhaps in direct debility “Since a free ventilation of nurseries has been practical the disease has been rare. laying aside the use of the preparations of alcohol has also been beneficial.” 13 Aphthae or Thrush White thrush from [illegible] (to inflame) This disease often appears within the mouth is then generally unaccompanied with fever. In some cases it is idiopathic but it more generally is a consequence of morbid affection of the primae viae # It is frequently found in adults of robust constitution which have been very much debilitated by previous that disease infancy and old age are most subject to it & in infants, as was just mentioned it is often an idiopathic affection In some families every infant is several with this affection. The vulgar error however, which very generally prevails that all children have the thrush at some sooner or late period other # is contradicted by the fact that many children as I have known never have the least appearance of it at any time “and it may probably in all cases, be prevented” The most feeble and delicate children are affected with the most violence, hence & from the fact of its being an affection of old age & a frequent sequel of other disease in adults, it may be inferred that this is a disease of debility & this [illegible] will be confirmed by the predisposing causes which we find to be, confined air, a very hot room & improper food# It is caused among the poor by bad air & among the rich by too great warmth & confinement. The fever likewise which accompanies it in many cases is of a typhoid character. # “Caused by neglect of the nurse by want of cleanliness & is often the effect of costiveness” # And have been led to prescribe remedies to prevent the thrush “commences on the inner part of the lower lip & corners of the mouth & extends over the tongue & inside of the cheeks & gums sometimes all these parts are affected & sometimes only one of them” “It appears in small eruptions or vesicles containing a whitish fluid resembling a coagulum of milk these vesicles often coalesce so as to form patches” “extend down the oesophagus to the cardia & here in all known cases it has stopped” Prof. Tully has seen p.m. [illegible] which the thrush the al canal [illegible] “The feces are sometimes covered with aphthous sloughs” “in its severest the eruptions are of a dark brown or deep red colour” “The alvine discharges are very acrid” 14 Symptoms – The disease is preceded by languor and sleeping This is so generally the case that it is common for nurses to say that the child is sleeping for the sore mouth In adults I have observed the same fact, & have predicted the appearance of thrush from the drowsiness of my patient # The symptoms of thrush are very obvious. It commences with white specks upon the lips #, angles of the mouth, & tongue effervescence. # In severe cases the specks in crease in number and size until they cover the whole inside of the mouth the throat & are found indeed upon the stomach x & throughout the whole intestinal canal though this is disputed. One thing is certain, whether these specks or flocculi extend throughout whole alimentary canal or not, viz. that they are found upon the rectum, agreeably the law that the orifices of tubes are most affected The white crust will fall off and be succeeded by one of a darker colour. The coats of thrush are often many times renewed & in this case the formation of a new one is preceded by unusually protracted sleep. A typhoid fever may accompany. It seems to be an eruptive disease determined [illegible] the al. canal. “In its milder form it is confined to some particular part of the mouth or to the mouth itself. The eruption is white & the mouth appears “as if a stratum of coagulated milk were spread over it” & but one separation of the curd like crust will take place. The general health will be but little disturbed” “In severer cases two or three successive crop are formed & the habit being unhealthy, the food innutrient, & the frame weak and atrophous, the under [surface] ulcerates and spreads & a low typhoid fever ensues” # “Your principal object should be to produce an excitement in the bowels by some mild medicine” # Because it is an eruptive disease however diaphoretic seen to be indicated & those which [illegible] action “The treatment is ordinarily a gentle laxative but there is a choice in the kind of laxative. Some practitioners recommend oily medicines, as butter, goose oil, pigs foot oil etc. But these articles do mischief As the vital powers of the stomach are weak, these oils will become rancid” # In such circumstances the oils become rancid & consequently irritate. I never allow oils to be given, yet it is a common practice to swab the mouth with oils, especially goose oil (or [illegible]?) # Chalk shd generally be preferred the other articles dissolve more slowly & may act in part mechanically” 15 It is thought that this disease has often been prevented, by giving soon after birth a teaspoonful of cold water & repeating the remedy every morning, for some time taking care also that the bowels be kept open There may be some foundation for this belief inasmuch as the disease is brought on by heat and debility. “In families where the children have uniformly been subject to this disease. I have recommended cold water as directed that the room should be well ventilated and the child not covered with too much clothing” In mild cases & where the constitution of the child is robust, a gentle laxative will be sufficient to remove the complaint # Castor oil is very often prescribed for it & it may be proper to five it to assist the operation of other cathartics But there are several objections to this article. It does not affect the secretions so much as other cathartics. It does not evacuate the contents of the bowels so thoroughly as others & it tends to # relax the coasts of the intestines, already in a state of morbid relaxation “It will not remove the mucus of the intestines” For mild cases magnesia is the best laxative where it can be given in sufficient quantities. If the bowels should not need a cathartic chalk or some one of the other testacious powders may be given “as [illegible] oyster shells, crabs eyes, crabs claws etc.” # Because it is an eruptive disease however, diaphoretics and articles which translate action seem to be indicated # “Give at first the clear liquor of this infusion and if this does not operate stir it up and give the substance (1) “After the stomach and bowels have been evacuated the ipecac should be given in small doses ¼ to 1/6 of a grain, to keep the bowels open, to produce a tonic effect, to determine to the surface & to prevent convulsion Ipecac has more claim to be considered as a specific than any thing else. It obviates the morbid secretions of the bowels it acts as a tonic never produces unequal excitement or other tonics & it does not like astrigents produce constrictions Whenever there is a tendency to unequal excitement it must be obviated or tonics will do no good” # I rely upon the ipecac though I use [illegible] sometimes especially white root asc. tul. # Indeed “if diarrhoea is present, prepared chalk is a good remedy as is also charcoal: the best form of which is burnt oak for this can do no mechanical injury” # “I have found this almost a specific” Since I have used this treatment I have not lost an infant by this disease” Ipecac in small doses as an alteration approaches as near to a specific in any remedy can # which is not to be expected # Astringents must be avoided, though tonics are indicated because they produce unequal & local excitement & stricture they must be given in the latter stages after excitement has been [equalised] A little borax may be given Moseley’s solut. zinc ziii al. zi [illegible] 1 pt 16 In the commencement of the disease if the symptoms do not indicate the probability of a severe case an emetic of ipecac is the best remedy Antimony has been recommended but it is not a safe emetic for children within the mouth Infuse [illegible] of ipecac in 6 teaspoonfuls of warm water & give a teaspoonful every half hour until the patient vomits or purges. # Ipecac has the advantage over antimony in its tonic and antispasmodic properties & in the mildness of its operation, never producing alarming symptoms # If the ipecac empties the stomach and not the bowels, a blue pill should be given of the size of from 2 to 8 grains. If this be found insufficient, it may be assisted by a dose of calomel, or magnesia or an enema (1) After the bowels have been thoroughly cleansed the ipecac should be given in small quantities a fourth or a sixth of a grain to determine to the surface & to prevent convulsions # If this dose moves the bowels too much, we may add “[illegible] or 1/6” one sixth of a 1/8 drop of Laudanum to each dose The absorbent powder or the white decoction may be given at the same time# Astringents should be cautiously avoided until the stomach and bowels been thoroughly evacuated # “& if there is much fever” Where this has been done we may make use of Moseley’s tonic solution, or cornus [circinata] [illegible] alba, or sericea or saffron safely & with advantage It is to be remarked that chemical action is prevented by the vital principle acting upon the food or articles introduced introduced into the stomach, and putrefactive or [acetous] fermentation if the vital powers of the stomach are [vigorous] This principle applies to vegetables Plants taken up in full blown in August and packed in live [sphagnum] will be preserved by the life of the sphagnum In thrush the powers of life are weakened & not only substances taken in but the secretions themselves are subject to fermentation hance the use of obviating the effects by alkalies limewater magnesia, chalk [illegible] absorbent powders white decoct. Rx. “To prevent the increase of vesicles of effervescences, syringe off the acrimonious fluid as well as you are able, by some diluent or detergent gargle and expedite the separation of the sloughs by invigorating astringents” vide Dr Good vol [illegilble] p. 30 “A little borax & ergot may be put into the mouth. But if the mouth is dry & parched, this and other astringent shd not be used. In such cases we should give mucilaginous substances as gum ar. slip. elm. or sassaf X 5 or 6 gr a drachm? of each in a gill of water # or viola pedata (parsley violet) or comfrey We must be very cautious about administering it to infants 17 To correct the acidity which often attends this disease we may administer prepared chalk or lime water & milk Or Rx magn. usta 10 or 12 fr. elix. pareg. xx gtts water zi given in teaspoonful doses every hour If the stools are watery and the child is robust give coct. ppt # vi gr. cal. 1 gr or the compd powder of chalk in doses of vi gr. or a small quantity fo rhubarb instead of the cal. For watery stools give dal. 1 gr & chalk 6 grs or compd powder of chalk It is too much the practice to scratch or rub off the aphthae in a violent manner with a brush or swab. As well might the cure of any other eruptive disease be attempted by violently rubbing or scraping off the pustules. Rubbing the mouth with a brush or swab until the bleeds is a cruelty which ought to be deprecated Still something must generally be done to the mouth in order to satisfy the importunity of nurses & prevent their mischievous attempts A little borax and sugar X is as safe as any thing If the mouth is dry it may be lubricated with muc. gum arab. slippery elm or sassafras twigs When the mouth is in a very high state of irritation probably a small quantity fo sugar of lead would be serviceable. I have not myself ventured to administer it to infants within the mouth For the proper local treatment of ulcers vide ulceration of the mouth From the sympathy which exists between these parts and the surface, tonics should be combined with diaphoretics I have given [illegible] [has] or [illegible] it is [illegible] observed by tonic and determines to the surface # It is mucilaginous sub-emetic & diaphoretic. It may be given freely as a wash or administered freely internally laxative diaphoretic soothing antirritant “The other [illegible] may be as good” The disease of which we have been speaking is a local disease 18 Ipecacuanha in this disease is emetic, tonic, diaphoretic etc. alterative & since I have used it I have not lost a single infant with thrush The viola pedata (parsley violet in some degree resembles ipecac is its qualities & may be internally administered in its stead # “give a teaspoonful of of the decoction” The peculiar kind of thrush of which I have been treating is a local eruptive disease of infants but as it appears in children more advanced it a critical determination of diseased action. It is not unfrequently a favorable symptom, particularly when it succeeds strong morbid action & [illegible] early in the disease In the latter stages & when the system is exhausted it is unfavorable For instance in hydrocephalus, when the whole mouth will sometimes become sore, and the disease seen to be translated to the mouth “from the brain to the muc. memb” In the latter stages of any disease not so fatal as hydrocephalus it is a very dangerous symptom of exhaustion “In cholera infantum it is a dangerous symptom. [illegible] there is not translation from [illegible] essential part” 18 ½ Eruptions in General Children of all ages are subject to various eruptions These are generally occasioned by the quantity or quality of their food. They are frequently cured by change of diet alone & the greatest attention should always paid to the diet is managing them Oily food particularly nuts, must be strictly prohibited, as they often cause eruptions. I have known some adults invariably affected with eruptions about the lips or other parts of the face after eating freely of walnuts Fish & poke week may likewise [illegible] the eruption We may use the tepid bath for the purpose of cleansing the skin. The frequent use of the [illegible] bath is important especially in chronic eruptive diseases of children & adults vide p. 21 & p. 20 For infantile [illegible] [illegible] p. 1831-2 of Good Case of a peculiar eruptive disease vide [illegible] [illegible] P. 1831 1 [illegible] art. The eruption was periodical, appearing at a certain hour every day At first a light coloured opaque elevation of the skin about half an inch log & a quarter broad like the sting of a bee or wasp. Soon after their appearance blood began to ooze from them & producing a drop which concreted into a scab, & at the end of 3 days fall off 8 or ten eruptions came out daily. Treatment was ineffective until a change of air & diet, which effected a cure “Child 8 or 10 yrs of age about 5 p.m. it would complain of a pain in the face then would appear elevation of the skin to the number of 10 or 12 the issue was treated as if [illegible] bark was tried also nit. sil. sulph zinc. arsenic & other minerals emetics cathartics new diet finally fruit was recom ate freely of oranges & was benefitted. Then change of air & travelling were tried or the first day the eruptions diminished & on the third disappeared In such cases try changes of mineral waters & dieting” 19 Red Gum Allied to thrush is that eruption called red gum The original word was red gown (from a sort of spotted red calico) which has been corrupted into red gum It is called by [Willa??] strophilus intertinctus It is a populous eruption & said to be peculiar to children but this last is doubtful The eruption is sometimes confined & sometimes diffused over the whole body. The papulae rise above the skin are distinct from each other & of a rarely contain lymph bright red colour. The vesicles contain by [illegible] only & terminate in scurf. Afterwards subsequent eruptions makes their appearance. The constitution is rarely affected. Physicians are not usually called unless the nurse is inexperienced Nurses give saffron Some physicians suppose this disease to be the same with aphthae. Dr [Willan] thinks they alternate. Dr Russell remarks “I think that aphthae of infants is of the same nature with those eruptions called red gum & differs in this respect that one disease affects the skin & the other the internal surface of the alimentary canal. Dr [illegible] thinks that this affection, preceded by sickness, arises from causes similar to those of aphthae, such as confinement, heat, irritable state of al. can. indigestion [illegible] If the disease be suddenly repelled from the surface, vomiting & spasmodic affections take place. Hence the European physicians Belonging to the primary [page] Probably the patient was not dieted so strictly as was intended & I recommended change of air Oranges however were beneficial. The was too fond of good living, fond of oily nuts There was a slight reappearance after it but of short continuance It was called [illegible], but improperly The eruption was preceded by a warming sensation of pain in the part. “Red gum is an eruption of fine pimples of a red colour affecting infants [illegible] within the mouth. It is a disease that rarely requires the advice of a physician The cure is much better effected by diet and [regimen] by the exhibition of medicines Still the physician is frequently called in and he must prescribe something if for no other object than to satisfy the friends In order any case give a decoction of saffron & snake root to keep the eruption from [striking] in & keep the bowels soluble with tinct. rhei compd tinct sennae magnesia, or other mild cathartics” 20 caution is not to expose infants with this eruption upon them to a current of cold air, or to plunge them into a cold bath. It is said that fatal consequences have resulted from such imprudence The child should be kept clean & be subjected to daily ablution of tepid water. Particular attention should be paid to the quantity & quality of its food. If the eruption should be repelled from the skin the tepid bath will be the best remedy This disease often occurs within the mouth & rarely requires the attention of the physician. [illegible] tone of the mildest of the eruptive diseases “We may give a decoction of saffron crocus? & snake root to prevent the eruption from striking inwards & keep the bowels soluble by mild cathartics such as magnesia & rhubarb. Still more will depend upon diet than upon medicine. Wine & water or one part milk & three water may be given” [belonging] to p. 18a “In managing most eruptive diseases more attention should be paid to diet than to medicine. In most cases it is requisite that the quantity of food should be diminished. If the food is milk, let it be three parts water, or substitute whey. Infants should take no animal food & no crude vegetables within the year. Oily food and the various kinds of nuts should be prohibited even for 2 or 3 years. A strong child in the country, with abundance of air and exercise might be indulged in such excesses with impunity when a feeble child in one of our cities would be destroyed by them” The eruption is so small as not to be observed It is not my object to treat of eruptions in general with minuteness but to give the general principles of treatment food etc. There are many eruptions met with [illegible] children which cannot be classed or be found described There is an affection of children appearing within the weak, which is not described at all. In three or 4 days after birth elevations of the true skin not of the cuticle upon the hands and arms & various parts of the body containing pus and [illegible] or as large, some of them as ½ dollar high [illegible] [fever] I have seen but few cases they were mortal. The books in such affections direct bark & tonics. The practice proved injurious. The disease as I have seen it has been inflammatory and required antiphlogistic treatment It may however be typhoid sometimes perhaps. If so it should be treated accordingly. I have seen but 3 or 4 cases. There were inflammatory. I prescribed in all these cases & from an analogy more fancied than real, between this & [illegible] Eruptions are generally caused by improper quantity or quality of diet. The remedies frequently get the credit of curing the disease when the amended diet cured the patient Oily & highly stimulating food should be avoided. All the nuts one of the worst is the pea nut 21 Strophilus candidus In this species of strophilus the papulae are larger then in any other of the genus. They are not surrounded with an inflamed base. They are very distinct smooth and shining & appear like little pearls under the skin of about the size of half a millet seed. They may continue for some time. A close examination is necessary for their detection. They appear on the bosom & chest They may accompany other diseases I have seen them accompany cholera infantum in the last stages & considered a fatal symptom [illegible] dyspeptic consumption a dangerous symptom The chest appearing to be covered with an oil surface, looking like particles of water I have seen persons attempt to wipe them off as if water had been sprinkled on the part Belonging to p 18 ½ Apples pears and fruits etc. Cleanliness also shd be strictly practised [enjoined] robust children, much in the open air, may have eruptions about the face mouth etc. with impunity when with the same diet delicate children, much confined, would have fatal eruptions, diarrhoea cholera infantum etc. The appearance of the [former] [have] [illegible] and the parents are often much alarmed. The disease is not dangerous however, & leaves no scar behind A scab is formed & the margin continues to suppurate and matter forms underneath “There is a thin [illegible] discharge from the part & the scab comes off leaving a thing pellucid [illegible]” The disease continues & this film is thrown off & the process is repeated 2 or 3 times It is sometimes occasioned by dentition sometimes it is an effort of the system caused by disturbance in the al. can. “A prejudice sometimes prevails with respect to this disease that it is an effort of nature & ought not to be checked It is a loathsome disease extremely unpleasant to both to the patient and the nurse & if allowed to continue some time it would not be safe to stop the evacuation, at least without keeping the bowels open” Some [Phys.] recommend partic [illegible] as specifics. Cal. or blue pill occasionally may be advantageous Buckthorn has been much celebrated in this and other eruptions It is drastic& hydragogue It is perhaps milder in form of syrup. Many families keep it. Half a dozen berries will operate If there is much plethora, the neutral salts may be given Magnesia also both for the indication & as a corrector I have known the muriatic ether much prescribed, but have not used it much myself, substituting for it mur. ac. as below 22 Crusta Lactea This is the [illegible] larvata of Bateman It appears on the lips, forehead & scalp in small pustules yielding pus, which eventually coalesce & form large loose scabs & perhaps extend over the whole face, down the neck and over the whole body. This eruption never leaves a scar behind it however long it may have continued. The skin is left smooth It is more unpleasant than dangerous, as the children affected with it are fleshy and otherwise health. When it has continued a considerable period of time, we must be cautious of checking it, as it is like a habitual discharge from an ulcer Treatment It is very common to give laxatives, such as syrup of buckthorn, neutral salts, magnesia etc. The sweet spirits of sea salt (diluted muriatic ether) is a very popular remedy. IT is given in doses of from 5 to 10 drops, diluted with water & repeated 2 or 3 times a day. I have seen this medicine given in hundreds of cases & am inclined to think it sometimes of service. It, at least give satisfaction to the parents & does no injury. If there is great irritability give 2 or 3 gr. of cal. with chalk. In cases where I have thought proper to remove the eruption. I have given the muriatic acid instead of ether, prepared in the following manner Rx mur. ac. zi alcohol zi Give [3] drops night & morning diluted with water make [oxyg.] oint. by adding the nit. ac. to lard until decomposition ceases, and the resulting ointment is tasteless. It has about the consistence of wax. Some add sulphuric acid but this is not decomposed & is acrid Sometimes the ointments seem to irritate & then we use [illegible] The best is the sulph. pot. zi to a porter bottle of water. Sulph. of soda does not materially differ, but it is unpleasant smelling like bilge water. In different cases apparently similar I have tried ointment & succeeded in one, but failed in another, & succeeded by waste I was led to adopt the use of sulphuret of potash from the analogy between its solution & the water [of] sulphur springs “We may with advantage make application of dry powders arrow root roasted flower hair powder taking care to give a cathartic when we check the discharge. We should pay particular attention to the diet both of the child and mother making the food weak & [simple] Laxatives will commonly be removed; a little magnesia & sulphur so as to move the bowels once or twice a day “A discharge like this may be checked with safety at the commencement, but when it has become habitual it should not be stopped unless a drain is made & kept open in another part.” 23 For this eruption I have found the oxygenated ointment, very efficacious in removing the scabs & healing the sores It is always safe if well prepared. ‘It is made by decomposing nitric acid with lard’ Perhaps the [citric] ointment (nitrate of mercury with lard) may be equally efficacious, but it is less safe. A good ointment may be made by mixing calomel zii with simple cerate zi or mutton suet zi The sulphuret of potash is one of the best remedies for this & other similar affections Dissolve zii in a pint of water & give a table spoonful night and morning also let the part affected be washed with a solution of twice the strength “It sometimes [illegible] two or three days and [illegible] [illegible]” Some prefer sulphuret of soda sulphuret of lime would also be equally efficacious Such solutions small like bilge water & are analogous to the water of sulphur springs I have sometimes used the sulphuret of pot. as an unguent. Sometimes liquid applications & sometimes unguents will succeed best, & if one fails we may try the other “Calomel ointment may be applied about the edges” If the eruption should suddenly dry up & fever ensue, a dose of calomel should be given & be followed by a few drops of antimonial wine 3 or 4 times a day or a small quantity of ipecac. White hellebore may be given Sometimes the eruption degenerates to a phagedenic ulcer. In such cases I have used charcoal eternally also a variety of poultices. I have seen much The const. irr. may expend itself upon the skin or upon the gland. syst. or upon the al. can. etc. We must be cautious about suspending them suddenly “It is important in all kinds of eruptions to keep the skin clean and soft & to effect this we should prescribe the warm or tepid bath, every day or 2 or 3 times a week. It removes itching and irritation, is always safe and almost always beneficial” May be caused by teething or by food etc. Such things often withstand various remedies & hence are prescribed for very empirically 24 benefit derived from the application of roasted flour. It absorbs moisture & excludes the air Eruptions attendant upon Teething Children are very commonly affected with eruptions when teething. They generally put on the appearance of a fine rash, but sometimes consist of distinct pustules containing matter As they are symptomatic merely, they require no particular attention to be paid to them & will disappear when the teeth get through. The worst consequences might result from their sudden suppression; as if this mode of action by which the system relieves itself from the irritation of the teeth, be interrupted, there is great danger that the system will relieve itself by morbid action of the brain, or other parts more essential to life Eruption resembling the itch Another kind of eruption appears on children of one or two years of age. It sonsists of distinct pustules like those of chicken pock, which form a scab, continue to inflame about the edges & contain a watery fluid It usually makes its appearance in summer & if not cured disappears spontaneously at the commencement of cold weather It has often been mistaken for the itch, and attempted to be cured by [?dock] root, but without success. The sulphuret of potash used as above is a good remedy The tepid bath is apt to be neglected but shd not Dock root often fails in this. It is often very successful in children’s eruptions. It is a very old remedy (centuries) Sometimes goes into oblivion & is again revived Prof. Smith thought most highly of R. patientie 6 feet high in gardens. Woodville mentions R [aquaticus] I know not that either is better than our [common] [illegible] I prefer the [Robtusifoli??] or [horserock] It is acrid and acts well when ext. [applied] and is good int. like rhub. R. crispus also has about the same properties but is milder. R. sanguinea is kept by many for it is as a specific for cutaneous eruptions. called also jaundice root & used in jaundice I have used them all and cultivated than all The leaves of the R. sanguinea have all red veins. You will often have such cuticles exhibited to you in families and be [illegible] of about them. Hence the importance of a knowledge of their prop. I have never known them in any but the children of [foreigners] I am inclined to think the taint may be dormant. The eruption at first resembles what is called “horn pock” “sometimes resemble a [illegible]” The nurse was changed & though the new one was health yet the ulcer appeared on her nipple 25 I think this kind of eruption might be cured by diet and the warm both. In all cutaneous affections the warm bath is very important to relieve the skin from every thing that may obstruct perspiration Eruptions & other irritations of the skin translate action from the viscera. Where irritated action exists in the viscera they are symptomatic Gutta rosea of drunkards is an instance of translation of action from the liver “When a cutaneous eruption appears we may generally apprehend that the al. canal is disordered” I cannot too strongly enforce attention to diet. Nothing will avail without it Venereal Eruptions These appear infants born of parents tainted with syphilis, though they may have no symptoms of it at the time of the birth of the child. Some physicians are of opinion that this child may inherit the disease from its ancestor the parents having been apparently free. The eruption appears in smooth hard, circumscribed elevations of the skin of about half the size of a pea 7 resembling a wart before it has seeds. They continue to increase slowly in size for two or three weeks, & become soft, containing a watery fluid in [honey] like substance Subsequently the skin gets rubbed off & leaves an ulcer with ragged edges & sometimes resembling a chancre which is very difficult to cure. I have known one instance in which the ulcer was communicated from the child to the breast of the nurse. Children affected with this Eruptions sometimes depend upon morbid state of the liver analogous to gutta rosea of drunkards Prescribe to the liver “The disease often proves very obstinate” Mercury does not seem to act as in the primary disease Corr. sub. given in this way is as safe as any other article The bowels should be kept free “I think the sublimate acts more on the skin & is therefore preferable to other mercurials” The plantain was once celebrated for the cure of cut. aff. I have known the plaintain in this way apparently cure after mercurials had failed Still the mercury might have prepared the system The plantain is an old English remedy for bites of spiders etc. It is treated of by Woodville & [Willan] It has as little acrimony I have some confidence in its efficacy. There is an old story about a snake & [spider] I have known nondiscript eruption which had resisted the prescription of several phys. cured finally by diet & change of air 26 complaint have a pale & bloated appearance & the powers of life are feeble Treatment. Change the nurse if derived from her Give corr. sub. in doses of 1/30 or 1/40 of a gr. Give the blue pill in moderate quantities but it subl. is better Give the tepid bath. Try the preparations of iron, such as the mur. ferri, or tartr. ferr. or the alkaline solution of iron. This complaint is not so easily cured as the primary [illegible]. Sometimes it will resist the operation of mercurials & all the treatment for scrofula. In this case send the patient into the country & try simple vegetable articles especially the expressed juice of the plantain (plantago major) externally and internally. It is a popular remedy for poison & is apparently valuable. I have known patients cured by the use of this, and of the air of the country. Still I think its main virtue to consist in its bland & mucilaginous quality [In these cases the whole lymphatic system is disordered & deobstruents are indicated. Now the expressed juice of most green vegetables id deobstruent. For instance the farmers make use of green rye in the spring for this purpose] Perhaps the expressed juice of the green plantain is deobstruent Infantile Erysipelas is an improper name vide Gray [illegible] of Erysipelas Good’s is an entirely different disease and his account will completely [illegible] Corresponds perhaps to the rose of the W.F. Goods account of the rash may do pretty well The infantile erysipelas of Europe described in the books is a different thing # Resembles shingles this is accompanied with fever The primary affection is of the al. can. therefore the attention is not to be directed exclusively to the skin I commences with [illegible] [illegible] you are to prescribe to the fever [illegible] This disease is distinguished by the eruption resembling a rose in the shading off of the colour from a dark rose to a light colour & in the concentric circles As I have seen the disease the rash has appeared in patches about the [illegible] thighs principally & the local affection gave no [illegible] and was trifling while the constitutional fever was severe and dangerous. The fever if not broken up in the commencement will resemble a severe case of [autumnal] remittent I have found no satisfactory account of the disease in the books, not even in the W. P. writers. I have however been informed a conversation with W. Indians that the rose is one of their most severe and dangerous infantile diseases fatal in a week and is treated by a vigorous administration of calomel # I have never seen the infantile erysipelas described as occurring in the European lying in hospitals contagious & terminating in gangrene I have seen common erysipelas upon infants however 27 Infantile Erysipelas The classification of this disease id doubtful. It answers tolerably well to the exanthesis roseola of Good “but [illegible] febrile” there is no species in Bateman & Willan which corresponds to it Efflorescence in blushing patches, gradually deepening to a “dark” rose colour, mostly circular or oval, alternately fading & growing brighter chiefly on the legs with irregular appearance somewhat like concentric circles if the patch is not circular the general circumference This is a disease of rare occurrence with us I have met with three or four cases. It is a severe and dangerous disease, apparently the same with the dangerous rose of the W.F. As it appears with us it is very different from the erys. that described by European writers & which is sometimes epidemic in their hospitals. In children in this country it is generally a disease sympathetic with a morbid state of the bowel The elevation of the skin is less than in erys. of adults the discoloration less deep in colour & the skin though a little tumefied is as smooth to the touch as if not diseased In the cases to which I just alluded, the erysipelas began upon the thighs & extended all over the legs. It was accompanied with considerable fever & a hot dry skin The colour of the efflorescence was purplish rather than red ‘We rarely see watery or bloody vesicles, as in other erysipelas’ I evacuated the bowels thoroughly with calomel (for the sake of the excitement rather than the evacuation) & rubbed the part affected The fever will much resemble that of infantile remittent “The spots are in patches from the size of a dollar to 5 or 6 times as large They are shaded in concentric circles from purple in the center to a lighter colour” “If the disease is not checked there will be increase of fever, constipation and tumefaction of the bowels irritation of the stomach affection of the brain, [illegible] death” Administer a full dose of calomel in the first place and repeat it once or twice. Work off the cal. with other cathartics. The secretion excited by the calomel is what we want. The cathar. subsequently given bring away Antimony in small quant. & nitre may be given until the liver is subdued “When the febrile symptoms run high pulse tense, tongue furred skin hot it is a very dangerous practice to apply discutients applications to the eternal affection Acetate of lead applied externally will probably translate the disease to the bowels” “Treatment I first give colored in full doses to alter the secretions to change excitement and promote evacuation, but do not depend upon it as a cathartic I then give [illegible] or [illegible] & [illegible] etc. to move the bowels I afterwards use the absorbants or alkalies, or ant. or iped. in small doses, as the case may require 28 It is attended with constipation & tumefaction & [illegible] of the bowels; with hiccup & severe fever, & may terminate fatally with severe coma “Pulse small & frequent child dies usually on the 5th or 6th day” “Dr Dewers says that in the cases he has seen the disease was not local but would spread rapidly over the body disappearing in one spot without leaving a trace behind it & breaking out in an other & perhaps a remote part thus changing from one end of the body to the other” Treatment. “Evacuate the stomach with an emetic, as ipecac” Clear the bowels thoroughly with cathartics, for the sake of the impression on the system. Give calomel in a dose of from 5 to 10 grs. If it do not operate within three or four hours repeat the dose. If necessary , work off the calomel with senna (or scammony?) adding aromatics if the stomach is irritable or with castor oil if the senna fails using also some laxative injection & the warm bath to assist. Then keep the bowels open with blue pill & “use some mild diaphoretic as aqua amm.” or give antimony from from 1/20 to 1/16 of a grain Pay little regard to the eruption and direct your attention to the bowels I have letters from physicians who have followed my directions & treated the disease not as a local one but with cathartics which testify the complete success of this plan of treatment. In the W.F. also where the “As palliatives after a strong impression has been made on the bowels by calomel, we may give sweet spirits of nitre, aqua ammoniae etc.” I have tried various either applic. without benefit I have “In those cases when the treatment wa local only the patients have uniformly died. I have not lost a single case to which I was called with commencement. I have conversed upon this subject with medical [illegible] out from the W.F. and find that the practice there coincide with mine” “When called to cases of some standing I have endeavoured to arrest the progress of the disease by a blister as [illegible] in gangrene & in the erysipelas of adults. The disease would extend beyond the blister just as if none had been applied” There is an erysip. affection which occurs about the head of children which resembles that of adults which I have treated with lead water 29 disease is frequent it is treated by the physician with calomel & cathartics. They give calomel 10 gr. & repeat it in 5 gr. doses until 20 gr. have been given I once saw a child with a swelling on one ankle supposed to have been produced by the sting of a bee or bite of a spider, which had resisted the operation of poultices & lead water. I gave cathartics but they did not operate, & the child finally died External applications of any activity should not be used, Still it may be necessary to apply something in order to satisfy the parents. The best will be roasted four “dried [illegible] [illegible]. Warm bathing will be very useful. If treated with lead water & cathartics not used, probably every case would be fatal. I have blistered in imitation of Dr Physick, but never with any advantage ‘If the disease be followed by diarrhoea give absorbents & aromatics such as compd powd chalk or white decoction. If followed by weak pulse etc. give tonics’ I have not lost a case when called early ‘This disease is supposed by some to be hereditary I have seen it affect infants on the scalp when it appeared to be a local affection merely In cases of this kind I have used lead water with [illegible] continualy advantage & without any evil consequences’ Cathartics however should be more or less employed in conjunction “afterward aromatics or tonics as the case may require” ‘It sometimes affects the brain’ [illegible] a more [illegible] or [illegible] intertrigo an attenuation & sometimes abrasion of the cuticle. The vessels forming the cuticle are diseased and the skin is formed in an imperfect manner It occurs also about the nates, [illegible] etc. where the skin folds upon itself & the air is excluded sometimes an acrid discharge Cullen thought it a very thematic affection. The skin looks like a new skin upon these parts. it arises from want of cleanliness & from confinement. The stomach may in a state of indigestion secrete an acid and the skin may secrete an acid. Exercise cleanliness treatment in general of eruptive disease When [illegible] flax they would burn a rag and put it in an axe & rub their finger on to harden the skin when chafed. A scorched rag is beneficial & use absorbent powders first nit. [illegible] might be used keep dry the parts Nurses apply “powder post” which is made by [worms] Sometimes it is a vesicular eruption which upon the head is called [farrigo] & in some situations is called ring worm To the [illegible] or intertrigo occurring in various parts the nurses sometimes apply the membrane from suet which is smooth keep off the air, prevents farther chafing and does well. The absorbent powders as starch alabaster etc. do well 30 Sore Ears This forms a very important subject in treating of the diseases of children. Nature has chosen the part behind the ear for eliminating irritation from the system. Under this head I shall speak of purulent discharges from the cavities of the ears & nose Slight blisters and ulcerations behind the ears of infants are very common & are in most cases, so mild as merely to require washing with cold water weak soap suds & with cold water, & being covered with a scorched rag or with roasted flour, to prevent irritation from the cap Frequently the discharge is acrid & excoriates the adjacent skin. Often a miliary eruption at the part commences the disease & is followed by excoriation Affections of the brain are sometimes relieved by a discharge from this part. The discharge is very important to children in time of teething & when affected with bowel complaints. If suddenly stopped fever may follow with full pulse, tense constipated bowels & fulness of the fontanelles & “often nearly all the symptoms of hydrocephalus” cold extremities Blisters behind the ears will generally restore the child to health When an infant is suddenly attacked with symptoms of hydrocephalus [illegible] disease, enquire whether it has had sore ears which have suddenly dried up, & if so, apply blisters behind the ears, for without them nothing perhaps will cure the new complaint. The same is true of old sore legs stopping of the [illegible] & other charges The theory of this, in all such cases, is the necessity, not The quantity of evacuation will not amount perhaps to more than a teaspoonful & the fullness of the fontanelles [rain] in the head & plethora is not owing to the quantity of fluid. The same plethora, pain in the head etc. will result from cessation of catamena which discharges will not amount to more than a table spoonful So you may bleed to the amount of pounds in cessation of a slight discharge for an old sore leg with out relief. while if you start the ulcer again by [illegible] or [mustard] the symptoms will be relieved Case of a man with ulcers on the legs of 10 to [20] years standing discharge stopped [illegible] pleurisy & aff. of liver the discharge restored by [illegible] blisters caustic etc. cure affected Sulphate zinc 10 gr. to oz or 2 oz may be applied Solution [illegible] sil. is one of the mildest application for irritated surfaces vide infra Oxygenated [illegible] is mildest & less apt to become acrid Sometimes when the aff is of an erysipelatous kind [illegible] relax the parts & are injurious Change the nurse also if necessary If the child is fed upon milk by hand, add perhaps a little magnesia or lime water Similar affections may affect the cavity of the ear & the cavity of the nose. If the cavity of the ear is affected in this way & neglected ulceration is apt to take place & the small bones affected causing deafness. First reject milk & water or carb. soda etc. [illegible] Finally if these means fail use stimulating injections myrrh finally [vit.] sil. In the use of [illegible] sil. external began with 5 grs to the oz & increase if necessary to xv or xx to the oz 31 of the evacuation, as is generally said, but of the habitual action of the system. This affection sometimes degenerates into a very troublesome ulcer, extending down the neck, accompanied with much pain & yielding a discharge so acrid as to excoriate the skin wherever it touches it Deep sores will be formed & the affection may terminate in gangrene & death In such cases it may be proper to apply emollient poultices of bread & milk; to which may be added poppy leaves, or pulverized stramonium seeds or ac. plum. Powdered gypsum is one of the best applications Alabaster gypsum is the finest kind Some apply red precipitate but gypsum is far better. Case in which this alone cured; Another physician advised red precipitate The oxygenated ointment if well made is a smooth dressing for them & is the best kind of ointment, where ointments do not disagree, as it sometimes the case. The bowels should be kept open with cal. or blue pill. It will sometimes be necessary to correct the milk of the nurse by administering magnesia & confining her to a simple diet Troublesome & sometimes fetid discharges on the internal surface from the ear arising from a kind of eruption may follow this eruption & may cause deafness if neglected I have known also the cavity of the nostrils & the frontal sinuses affected in the same manner. A cure may be affected in either case by exciting the discharge behind the ear though it may be necessary to keep it open for some time If this fails use (in addition?) milk & water Milk 2 part water 2 part lime water 1 part Tinct. of myrrh if the discharge is fetid & troublesome a teaspoonful to a gill, as an injection for the ear Sol. nit. sil. 1 or 2 gr to oz. water? externally Be very careful in watching the symptom Case of a young man who had had such a discharge for years checked by astringents [delirius] inflammatory fever ertc. bled cathartics etc. Porrigo galeata ([helvetea]) Cuticles below the scales dotted, shining Said to be contagious. I have never happened to see it so though I do not doubt the fact. I have never seen more than one in a family have it A very troublesome complaint The hair becomes pale, perhaps the roots are affected in which case mercury is indicated. Salivation seems to do no good I have seen it practised without any benefit Recent cases I have cured very speedily with oxyg. ointment. Any smooth substance applied to the part & excluding the air, will often cure as for in stance a bladder, or the membrane of suet what is useful also for [fret] Poultices do well, whether upon this principle or moisture changing secretion When a student I recollect there appeared a strong recommendation of poultices A physician of my acquaintance prescribed a poultice & left his patient. It adhered the hair grew into it and the hard crust formed a helmet indeed. It [was] a long time a period of week, before it was removed When it came off however, the disease was removed! 32 Tinea Capitis. Scald Head porrigo This is a local affection & yet much influenced by diet. Sometimes however it affects the system, or is sympathetic of a general affection of the system. The disease consists of scaly eruptions, eventually covering the head with a hard & generally brownish coloured crust. The hair often comes off. Cleanliness holds of course the first place in the list of remedies; the head should be carefully shaved and washed repeatedly with soap and water. Perhaps as successful a mode of treatment as any will be to shave the head closely and apply a bladder or affect skin in close contact with the skin. It excludes the air. Sulphuret of potash zfs or ai to a porter bottle used as a wash & given internally tablespoonful 3 times a day has cured the complaint in a few days mercurials or corrosive sublimate will be useful, but do not always cure. Sulph. prt. internally zii to lb i [illegible] ext zii to lb is [illegible] The ueast poultice is good, but care should be taken that it do not become dry on the head, which should be first shaved. The oxygenated and the citrine ointments have been found useful, as had also the tar ointment which is made as follows Rx tar ziv wax zfs sulphur zi or is Mercurial cathartics should be given from the first and particular attention paid to the diet. # vide last par. The practice in this complaint has been quite empirical & a great variety of remedies, have been popular. Veratrum viride & v. albus & [apocynum] [androsaem??] olium have used for external washes. Syrup of buckthorn is recommended as a cathartic. Muriatic acid Lunar caustic about 6 grs. to zi of water (rain water) well water may decompose it Decoction of cocculus indica, is given internally & externally. Cal. zii al burnt zfs red lead zfs z6 zifs spermaceti cerate head shaved & washed with soap sude every night and afterwards apply this ointment. It is given by [illegible] & Bates [illegible] & called Diet must be attended to Terebinthinate ointment as tar ointment Tar ointment is made of tar and lard or tar & simple cerate There is no difficulty in the diagnosis of the disease. You will be called to prescribe for scalled head and you will find that the nurses have not mistaken the disease. It begins with small pustules the matter [illegible] which is acrid and soon forms a scab over the whole head. The treatment must be principally local. But mercury may be given occasionally. I have not derived much benefit from the common mercurial ointment. Citrine ointment is good however. Also cal zif lard zi 33 has been used 3 or 4 drops in a wine glass of water Finally the sorts of the various species of dock (rumex patientia, crispa obtusifolia, sanguinea, aquatica etc.) have been much used All the species have about the same properties, being acrid purgative etc. They are given internally as cathartics, & externally applied, made for instance into an ointment, by pounding up the fresh root with lard. The following is a recipe Rx yellow resin zii best ale lb i finest flour ziii mix the all & flour thoroughly together & add them gradually to the melted resin. # The tepid bath may be used when this is used always take care to have a supply both of hot and cold water in order to keep up the proper temperature. Ipecac may be administered to equalize excitement in some cases, & as a valuable substitute for this article we can use the root of asclepia, tuberosa, which is expectorant, diaphoretic and laxative. “Vary the remedies according to their affect soften use decoct. rumex particularly r. obtusifol. called horse dock. It at firs increase, the irritation & secretion. Use it externally & internally” The excitement of the al. can. is affected also of the nervous system Various cutaneous aff. different kinds also of local inflammation, or erysipelatous phlegmous gangrenous scrofulous the inflammation varying according to the constitution scrofulous gangrenous I have frequently heard Pres. Dwight speak of the pain he experienced in cutting his wisdom teeth suffered extreme pain for a whole summer She did not appear to me to look like a person in the consumption I was puzzled [illegible] [illegible] I looked into her throat and mouth and found she was cutting r wisdom teeth # The irritation may continue for mouths, from the pressure upon the gum Those who commence cutting teeth at 10 mo. to a year or even later do not necessarily suffer more Delicate & scrofulous children suffer more 34 Dentition Among the causes of infantile diseases no one more claims the attention of the physician than dentition. The bowels and the nervous system are always more or less affected by it & to this cause we are frequently to refer affections of the lungs of the brain, of the ear, of the skin, of the glands, & of the cellular tissue in general. On this subject there is however a difference of opinion, for it is said by many medical men that children which are healthy # well teeth with as much ease as adults. Allowing for the peculiar irritability of [illegible], no doubt they do, but in granting this we concede nothing, for adults often suffer extremely from dentition. I well recollect the case of a Mrs Waters perhaps about 20 or 21 a married woman and the mother of said to have a [illegible] several children, who was supposed to be in the last stage a good deal of cough etc. had raised a little blood on consumption & upon examination & found was cutting the four wisdom teeth. The gums were divided & antispasmodics administered, when she recovered perfectly. # Case of Mrs Purcell’s child had been sick with diarrhoea and fever for some time a flush of fever coming on every day. I had previously extracted defective teeth from the [illegible] mouth. I now looked into the mouth lanced the gum over a double tooth gave no remedies The period of dentition commences at different ages times in different children, varying from the fourth to the sixteenth mouth, but most commonly in the sixth. The two central incisors of the lower jaw appear about the sixth month and are followed in about a month or six weeks by the corresponding teeth of the upper jaw. very [illegible] [illegible] [illegible] cases I have known a double tooth cut first in others an eye tooth in others all the teeth at once You must always examine to see what teeth are cutting You will perceive the gum swollen and harder Some children are born with teeth but such teeth re merely attached to the gum and are useless and should be removed Sometimes there is too much anxiety about dentition generally however not enough Case of a child mother called me insisted upon # irregular distributions of temperature are [illegible] [illegible] hot 5 [illegible] cold 35 Next come the inferior lateral incisors & after these the corresponding teeth above About the twelfth or fifteenth or 20th month appear the anterior molares & are soon succeeded by the cuspidati those of each kind in the lower jaw cutting through before those in the upper. Next we have the posterior molares. The last molar teeth are not found in the child & hence their name, dentis sapientiae. They appear from the 18th to the 25th year. The above is the order in which the teeth commonly appear, but they often come irregularly, sometimes the lateral incisores, sometimes the molares, & in a few rare instances the cuspidati appearing [illegible] Some persons never have more than two incisores in each jaw Occasionally we meet with families who are said to be destitute of teeth. I have known a family from Charleston, who had this peculiarity. The fact however is in such cases that the teeth exist but not rise above the level of the gums, so that they are not ordinarily seen Such teeth have this advantage, that they are not subject to decay & are also very serviceable. Whenever between the fourth and the eighth 2nd year? month symptoms of irritation exist, the cause of which is not obvious, the state of the teeth must be examined. The symptoms of difficult dentition are fretfulness inclination to bit hard substances, putting the fingers into the mouth, slavering, starting in sleep eruptions about the face & on the scalp, flushings in the cheeks. # hot head pupils contracted sometimes dilated sometimes losing their brilliancy In delicate children the eff. will be more chronic & in vigorous more acute The system relieves itself often by evacuation and this is considered often a good symptom as [illegible] there is a great flow of saliva. The system relieves itself by diarrh. by salivation by sweating [illegible] by every mode of equalizing excitement which is the great principles on fevers & indeed in most diseases 36 and cold feet, irregular paroxysms of fever, remitting fever vomiting diarrhoea irregular & green stools wine small in quantity & voided with pain or in large quantities and of a pale colour bloating of the hand feet and face contracted pupils. All the symptoms indeed of extreme irritation may be met with & we likewise find in many cases a tendency to phlegmonous inflammation suppuration in various parts of the body particularly in the ear. Case of a child who was thought to have an affection of the brain. A tumour was found under the arm. Sometimes dentition is accompanied with phlegmonous local inflammations in different parts of the body & suppuration of the glands about the ar by which relief is afforded Ricketty children cut their teeth more slowly than others but not in general with greater difficulty. The child must be held, and the fingers keep in the mouth to keep it off the tongue # The guard being made with a spring, so that when pressed upon the guard will yield and permit the lancet to descend (in the slit of the guard) 37 Treatment. The first and most important indication is to divide the gums with a gum lancet or other convenient instrument. The operation is not usually painful the child will even press against the edge of the lancet. The relief is often immediate and permanent Some relief may indeed be afforded by rubbing the gums with a hard & polised substance & by giving the child something of the same kind to bit, but the most effectual relief will be afforded by the lancet. The chief difficulty in the performance of the operation consists in confining the child. It may be done while the child is asleep & often without waking it. We must also be cautious not to cut the tongue To prevent this it would be better to make gum lancets with a guard # For the double teeth two incisors should be made & it may be necessary to make a transverse one in order to divide a band of a sort of ligamentory substance which confines the tooth. It is sometimes objected to cutting the gums in particular instances that, if it is done too early, the cicatrix formed by the healing of the incision will subsequently render it more difficult for the teeth to push themselves through This is not true for the cicatrix though apparently harder [illegible] less vitality in it than a part which has not been wounded and will be more easily broken through Solution of continuity is more easily made by disease in a cicatrix than in a part which has not been wounded vide J. Hunger. It is a common maxim that an old scar is apt to break out in to a sore The gums should be divided as often as there are any symptoms of irritation, until the teeth Some other diseased action may exist in the system, and the irritation of the teeth be superadded the lancing will only relieve the latter # For the gums having been exposed for a long time to irritation because [illegible], and perhaps ulcerated and are kept irritated by contact with the hard tooth 38 get through I have repeated the operation three or four times upon the same teeth. In some cases however cutting the gums relieves the symptoms only in part. Indeed the irritation sometimes continues after the teeth get through # “use astringents” If any disease from the causes attacks the child during the period of dentition it will be very important to remove all irritation from the latter source, for otherwise all the symptoms may be aggravated & a disease be rendered mortal which would otherwise have been mild. In children of a vigorous constitution dentition is often accompanied with inflammatory symptoms which require an antiphlogistic plan of treatment. Lancing the gums will then be useful as local bleeding & it may even be advisable to bleed from the arm though a few leeches behind the ear are preferable. It must not be forgotten that in infants, the bowels afford a great outlet to diseased action and to irritation: hence the frequent occurrence of a spontaneous diarrhoea. If the patient is costive or if it has a diarrhoea, a dose of calomel should be administered & if the bowels are soluble a milder mercurial, as blue pill may be given. During the whole period of dentition the bowels should be kept open by such cathartics as the state of the system may indicate, such as magnesia, rhubarb etc. adding aromatics if the system is relaxed and debilitated & chalk if there is acidity If a diarrhoea suddenly stops and vomiting supervenes, externally irritant to the [illegible] [surface] generally, injections, calomel The skin shd be kept moist for diaphoresis is one of the most powerful means of equalising excitement etc. If there is much perspiration you may depend upon op. alone but whenever there is much [unequal] excitement opium alone will not do well and ipecac shd be combined with it in small doses # Also by drafts to the [illegible], by local irritants to the skin generally also keep the bowels from remembering that there is no outlet to the brain 39 and the warm bath are to be used, as has already been mentioned under the head of diarrhoea Another & a powerful mode of equalizing excitement & relieving irritation is by diaphoresis. For this use the warm bath & small doses of ipecac & opium or of antimony and opium. Opium will always be useful to allay irritation & particularly if combined with ipecac or antimony, & always safe when there is no determination to the head Small blisters behind the ears relieve the symptoms of dentition & prevent the disease from terminating in hydrocephalus. # If these cannot be kept behind the ears mercurial ointment or cantharides may be applied to the same part. Nervines may be employed either with our without ipecac During dentition exposure to dampness & to currents of air should be carefully avoided & the patient should be kept warm X summer & autumnal epidemic Indeed the effects of it sometimes continue through the winter The desire often resembles spasmodic cholera in the premonitory diarrhoea & the sudden collapse 40 Cholera Infantum This disease appears in New Haven in the month of July August September & October. It rarely commences until the latter part of July & in October there are few cases except those which have commenced in one [illegible] other mouths & continued until this. Indeed cases are sometimes prolonged till the middle of November Symptoms. It begins in various ways; most commonly with diarrhoea, which may continue for days & even weeks without any very alarming symptoms; At other times times with violent vomiting & purging accompanied with high fever. The discharges from the bowels very much in their usually [illegible] from natural colour [illegible] [irritated] [secretion] appearance. Sometimes they are yellow, brown or green, sometimes in small quantities & slimy and bloody & at others in large quantities & watery, smelling like water in which putrid meat has been washed. Worms likewise may be found in all these various sorts of discharges “dead in the advanced stages” The disease is usually accompanied with great restlessness & often with severe pain, which increases by paroxysms at intervals of from fifteen minutes to two hours The pulse is usually quick and weak, the head hot and the extremities cold. The fever is ordinarily remittent but the exacerbations are frequently quite irregular The disease is attended with thirst often [illegible] and after drinking the child vomits. The eyes often appear languid and hollow During the whole progress of the disease [volvulus] may occur Be on the look out for it “The termination of this disease in hydrocephalus I have reason to think is more rare than is commonly supposed. Many cases of this kind occurring in my practice, I have reason to believe were cases of volvulus Or varying from cholera morbus of [illegible] [remittent] bilious fever sometimes putting in the form of cholera of [illegible] at others that of remittent bilious fever 41 while in other cases they may have an unnatural brightness as in pulmonary consumption indication a high degree of mental [illegible] excitement “of bad symptoms” Sometimes the eyes are half open during sleep, as is indeed the case in various bowel complaints of children when severe we often find the diseased action translated from the bowels to the head and terminating in hydrocephalus. Volvulus also may be another termination. Sometimes the vomiting ceases for several days and then returns, while the diarrhoea continues the whole time Duration As to the duration of the disease, it may be very rapid in its progress & terminate fatally in forty eight hours, or continue for months, & the symptoms may vary very much during the progress of the complaint. A damp hot atmosphere will aggravate all the symptoms, while cool weather with the wind from the northwest will mitigate them. In different seasons also cholera infantum will have symptoms peculiar to the year, varying in this respect like other epidemics Finally when it proves mortal, the child is carried off in convulsions, or is worm out with emaciation & dies with aphthae while in some cases death is ushered in by hydrocephalus, volvulus & other diseases Causes. We may consider the cholera infantum as an epidemic sometimes an endemic confined to a particular season of the year analogous (in its grade of action) to the cholera morbus o f adult “This disease is perhaps most analogous to a remittent bilious fever varied by the peculiarities of the [illegible] [illegible] will see in [Jackson] all that can be said in [favour] of the opinion. The very fact that it is often [illlegible] disproves the opinion besides the fact that the disease does not occur at all seasons during the period of dentition The disease is affected by the state of the atmosphere being much aggravated by a damp state of the air always minded by a cool bracing northeast wind The kind and gentle excitement produced by nursing is important in chronic disease “Children should not be weaned till dentition is complete or till 1 ½ years & in the fall” 42 infantile constitution” Dentition has been considered by some as the cause of cholera infantum but to this opinion I cannot assent thought it is held by Dr Jackson & many of our most respectable physicians Dentition may indeed be an exciting cause; it often aggravates all the symptoms & accelerates the fatal termination yet in the winter spring & months it does not produce the disease of not unfrequently children are affected with cholera infantum without any appearance of dentition Worms sometimes make their appearance during the progress of the disease but they cannot be considered as a [illegible] or cause of it. When they exist during the complaint the irritation which they produce must be obviated by such anthelmintics as are not contraindicated by the state of the system. “I think I have seen the [illegible] productive of unfavorable effects.” The cholera infantum probably arises from the same remote causes as the (cholera morbus) & the bilious remitting fever of adults such as damp hot confined air (which can be counteracted only by exercise in the open air) want of cleanliness & bad diet. Improper food may be both a remote & an exciting cause & the same is true of a bad state of the atmosphere muggy or [illegible] of inequality of temperature & exposure to cold. The predisposing cause produced by these remote ones is debility Children weaned in the spring are mor apt to have this complaint, & do not bear the disease so well as those at the breast. I would therefore advise that in places where cholera infantum prevalent. children should be weaned in the fall 43 Some consider malaria the cause Like dysentery this is a disease translated from the surface to the first passages. The fever is of that kind which Sydenham calls febris introversa the action being of an irritated kind in general & rarely of an inflammatory Commencing at the skin & breaking up the balance of the system by obstructing the perspiration the morbid action is transferred to the mucous membrane of the intestines & involves the liver, pancreas & all the glands immediately sympathizing with them. Indications. The indications are 1st To evacuate the first passages; if this has not been already done by the disease itself 2ndly To translate action to the surface & in general to equalize excitement 3dly To excite healthy secretory action and regular peristaltic motion of the bowels 4thly To avoid the causes of irritation and to remove irritation when it exists 5thly To restore the tone of the system & particularly of the stomach and bowels 1st When the disease comes on like the cholera morbus of adults, the stomach and bowels are sufficiently evaluated by the disease generally when the phys. is called and no evacuation s are to be used. It is to be treated like cholera morbus with aromatics as essence of peppermint, with Laudanum We must be careful not to prescribe for the [name] of the disease nor necessarily pursue the plan of treatment generally proper. Often you will find the patient so much debilitated at first as to require stimulants & acrids When we have the collapse stage and a collapse may recur in any disease then the practice of the nurses is correct in acting on the skin Some recommend large doses of cal. [illegible] much smaller the [common] Dr Jackson recommends large doses common in the commencement. Dr [illegible], 1 gr. doses and salt & water I recommend cal. from 1 to 10 gr Though sometimes small doses repeated may change the secretion better than large, yet often a large dose will operate more kindly, then a small one [which] merely irritates “Dr Dewers recommends injections of salt & water 2 or 3 teaspoonfuls to a gill, instead of cathartics. Repeat the injections till full catharsis is produced the morbid action is changed, by translation of excitement from the stomach & small intestines [illegible] [illegible] with cal. ¼ gr. every [illegible] to alter secretion 44 with counterirritants, as mustard, horseradish & brandy on the epigastrium & abdomen with the tepid bath & with injections of starch and laudanum. But when it attacks with a diarrhoea, accompanied with occasional vomiting unless the constitution is very feeble constitution [illegible] extremely delicate the stomach should be evacuated by ipecac and the bowels by calomel or blue pill To vigorous patients & often give in the commencement six grains & would not hesitate to give 10 grs of calomel & an hour after give from one to ten grains of ipecac according to the age and vigour of the patient for in this way the stomach and bowels are more thoroughly evacuated than by giving the calomel after the ipecac has ceased to operate In some cases a single dose of calomel will thoroughly evacuate the bowels, but in others it will only remove the contents of the stomach and small intestines into the colon & a dose of castor oil must be given or one of senna with aromatic seeds The southern physicians, make less use of cathartics and depend much upon stimulating injection, as of salt & water 3 teaspoonfuls to a gill. This practice does not succeed well with us. They also give smaller doses of calomel. This also I cannot approve for a large dose of calomel, ten grains for instance, will evacuate the bowels copiously and kindly, when small ones produce scanty stools, with irritation of the stomach and tenesmus. I may mention also that the French expectant plan of treatment adopted in Philadelphia will frequently be utterly inefficient. Where excited has not been equalized, calomel or any other cathartic may act upon the duodenum only and not produce Such facts as there have been given rise to the opinion that the disease arises from stricture but then the al. can. may be subject to unequal action as much as the skin # a castor oil with elix. sal. aa zi every 2 hours # Yet this practice shd not be adopted indiscriminately where there is weak morbid action accompanied with coldness of [surface] etc. the exhaustion of cathartics will be injurious This is the most important principle in the cure of diseases Sometimes cath. cure the diarrhoea, where the action is unequal. For instance the lower intestines may be torpid and the feces accumulate, the bowels above may be irritated and a diarrhoea of [small] liquid stools may pass by the feces 45 If calomel or any other cathartic produces watery stools in which are small pieces of feces of an ordinary appearance, and there have not previously been copious evacuations, we may conclude that a thorough evacuation of the bowels has been prevented by a spasmodic action of the intestines which has constricted them in places, & confined, perhaps a large quantity of fecal matter. Indeed this may be proved by the success of the treatment, which should be the administration of a dose of opium with a little calomel to change action followed at an interval of one or two hours by a dose of z ¼ and z ½ castor oil or elixir salutis teaspoonful #. It is of the first importance in all typhoid diseases, particularly in those affecting the bowels, that thorough evacuations should be made # 2ndly so translate action to the surface and equalize excitement This indication will be answered by an emetic at the commencement, as already directed & by small doses of ipecac, repeated throughout the disease, & also by small doses of mercurial medicines opium being conjoined in many cases, as will hereafter be mentioned. In some calls where there is much arterial action antimony is preferable to ipecac & the lancet or leeches may be indicated but such cases are rare This indication is also answered by applications to the abdomen of fomentations, with decoctions of aromatic herbs sinapisms, blisters, burdock leaves, horse radish leaves, ginger in spirits aq; amm or the Ulceration of the bowels is generally preceded by aphthae both are effects not causes of the disease “An [epispastic] should not be applied after aphthae have made their appearance. If the pat. is languid & sleepy we may suspect aphthae.” Diluents may be used Obviating irritation by opium is often necessary to have the proper effect of cal. for instance Give opium first & follow with cal. & often you will succeed in obtaining the effect of the cal. when you had failed before “Ipecac when it acts as a cathartic is more apt to produce fecal stools than any other article 46 terebinthinate oils An epispastic upon the epigastrium is very useful to relieve irritation of the stomach & to prevent ulceration of the bowels and aphthae. The warm bath will tend powerfully to equalize excitement will relieve vomiting, quiet restlessness, produce a uniform perspiration & if used at evening, procure a quiet nights’ rest. It may always be used and at any time, unless the patient is in a state of exhaustion. As a substitute for ipecac, the root of the asclepias tuberosa may be used. It is much used in infantile diseases as diluent, to determine to the surface & to promote expectoration. 3dly For changing the secretion of the stomach and bowels and keeping up a gentle peristaltic motion I have found small doses of mercurial cathartics with ipecac of opium superior to all other remedies. If any article deserves the name of a specific in any disease, it is ipecac judiciously administered in cholera infantum. It relieves this disease with more certainty as certainly as than cinchona does intermittents. It may be observed however that a man successful with one remedy only m ay be compared to a mechanic, very skillful with a pen knife! My method of administering the articles is the following. For a child four months old, mix 4 gr. of ipecac & 5 drops of laudanum in twelve teaspoonfuls of water & give a teaspoonful every fourth or fifth hour & at the same time give so much of the blue pill as to You will know when the blue pill begins to have its appropriate effect by the change in the color of the stools Pills of blue pill may be given without much difficulty to children there is little taste except of the saccharine matter. They may be given in food [illegible] dried huckleberries which I have often called for in the country where there was difficulty in administering remedies. There is often great difficulty with respect to this. A child will often scream at the sight of the doctor Opium to allay the irritation of the stomach and prevent the ipecac from being thrown of Ipecac to equalize excitement & determine to the surface Ipecac also, to qualify the opium # Or if this cannot be done, introduce a paste of opium just within the sphincter # Case of a child in a family where 3 or 4 children had previously died of chil. inf. [Lax] & [illegible] habit etc. I commenced the treatment with the pill and ipecac I treated it mildly giving blue pill instead of calomel N.B. For such cases [illegible] 47 procure an evacuation from the bowels two or three times in [never twice] in the twenty four hours. For a child a year old take twice as much ipecac & laudanum with the same quantity of water and give it in the same way. Sometimes three times the quantity of laud. will be necessary; for instance if the child has been in the habit of taking it or if the diarrhoea is very urgent If the diarrhoea is urgent, it may be necessary to administer injections of starch and laudanum & to apply to the abdomen ginger & grandy volatile liniment poultices or other irritants The enema may be made with three table spoonfuls of flour & about 3 or 4 times as much laudanum as you give by the mouth say 10, 15, or 20 drops. # I prefer flour to starch because the foreign starch often contains acid. The chalk mixture or white decoction may also be used. # “Children of a bucophlegmatic temperament and lax habit are very apt to have this disease & with them I have sometimes commenced the treatment by administering blue pill & ipecac.” The success of this plan of treatment will be strikingly shown by the following case. A child 10 months old was taken sick in this town last summer, with cholera infantum, grew worse and was directed by the physicians to be carried into the country Unfortunately the child was carried to a situation not more elevated than N. Haven & while there its strength decayed and all its symptoms were aggravated. The parents despairing of it recovery returned with it to N. Haven & sent for me with a request that I would do something to alleviate its sufferings On recovery from the disease they usually crave [salt] food and salt is a grateful stimulus 48 I found it in a state of emaciation, with hippocratic countenance frequent vomiting, urgent diarrhoea, with stools fetid, watery and containing some slime and mucus, & leaving streaks of blood upon the cloths. The countenance and gestures, expression of great anxiety, and there were frequent paroxysms of extreme distress. I directed ipecac 5 gr. & laud. 10 drops to be put in 10 teaspoonfuls of water and a teaspoonful to be given once in four hours flannel wet with ginger and brandy to be applied to the bowels & gave 5 oz. blue pill, & ordered the diet to be of arrow root flavored with a little brandy. After the second dose the vomiting stopped, the stools became less frequent & within 24 hours the complexion of the stools was much improved. The next day the same medicines were continued and four drops of the tonic solution with a little brandy and water. On the fourth day from my first visit, the child began to relish salt fish, which was allowed Capt. Dennison’s children To correct fetor in the stools we should give charcoal. Carbonic acid, by injection, is given for the same purpose. The mode of injecting carbonic acid, is to place chalk & vinegar in a bladder, and force the gas into the rectum, as it evolved. “This is recommended. I have tried it but not very thoroughly” But if vegetable food undergoes the acetous fermentation it shd not be used. The putrefactive fermentation however is more injurious than the acetous 49 4thly The most common cause of irritation is dentition The gums should be often examined, & be divided if they appear at all swollen. All kinds of food that is hard of digestion should be carefully avoided though for children somewhat advanced perhaps a small quantity of ripe fruit may not be injurious If the child has not been weaned the milk of the mother will be the best food; for those children’ who nurse are more apt to recover than those that have been just weaned. The act of sucking is highly soothing and gratifying & operates like a nervine medicine. The best food for children that have been weaned, will be arrow root, with a little brandy or wine as a condiment & as a substitute for this & similar articles from the shots, we can direct a porridge made of roasted flour. If in the latter stages of the disease the child craves any particular of food, as salt fish, or salt meat, or wine or brandy, it should be given, & all kinds of medicine laid aside if the stomach leathe3s them; for strong disgust will debilitate by exciting nausea. Frequently however we can succeed in preventing this effect, by a different mode of administering the medecine the sight of the spoon for instance may may give rise to the loathing & nausea. With respect to food we may lay it down as a general rule in such cases that when the powers of the stomach are so weak that food must undergo fermentation in it, vegetable diet should be preferred to animal. For local irritations, various applications should be made & various articles administered, especially in the latter stages “Tea juice? boiled beef a teaspoonful with pepper & salt is grateful frequently & checks vomiting but at first vegetable preparations are better” vide supra The chalk mixture made with a little opium in some cases or with astringents etc. a valuable [illegible] 50 of the disease or when we are compelled to try a variety of remedies. When there is unequal excitement & unequal temperature blisters may be used. Blisters sometimes produce perspiration. To relieve irritation of the stomach effervescing mixtures may be drunk, they are often more grateful. [illegible] we may fill the stomach where there is vomiting and dilute its contents with a tumbler of wine whey I have often succeeded with it with a teaspoonful of aqua ammoniae in it as being thrown up will be no objection. If the disease commences with much irritation in the stomach, it may be useful to overcome it by counterirritation in the rectum produced by an injection of soap suds or of salt and water 3 teaspoonfuls of salt to a gill of water, for a child a year old. Dr Dewers relies must upon this latter article in the commencement of cholera infantum and repeats the injections until the bowels are fully evacuated. He likewise recommends small doses of calomel, a quarter of a grain for instance repeated once in an hour until the bowels are evacuated. In cases of irritation of the stomach & torpor of the liver & portal system, this practice of salt & water & small dose of calomel does well. In chronic cases he gives magnesia rhubarb & opium. With respect to small doses of calomel it may be further observed that they will not answer when the intestines are much coated with mucus & that in some localities they do not answer so well as in other places. On the shores of lake Erie for instance the physicians are obliged to give large doses of calomel than we give There are cases in which small doses seem to irritate & large doses operate kindly “In the latter stages Rx magnesia grs 4 SS gtts Rhei gr i.” C. Florida not so pleasant but loses its mawkish & herbaceous taste by keeping (like peruvian bark) The spiraea is though less inclined to act unequally in this state than most other astringents If one astringent wears out try another Oak barks Rose [illegible] (salix [illegible} “A valuable popular remedy” has mucilage combined seeming to resemble ([illegible]) [illegible] was formerly much used but is now superseded by native articles It is well known that because These astringents are often prompt up is specific [illegible] virginica was specified good [illegible] & [illegible] it e.g. viburn. lentigo, raspberry, blackberry, [illegible] [illegible] root decoction recommended by Dr Rush thought to deter to [illegible] used by many) [illegible] bark has [mucilage] There is apt to be a paucity of [urine] in this disease as well as in Diarrhoea & dysentery and then diuretics are indicated and are highly valuable 51 5th When in the latter stages of the disease the principal indication is to restore the tone of the system & particularly of the stomach and bowels we must make free use of tonic and astringents. Moseley’s tonic solution will be one of the safest and best articles in this stage. If the bowels, by a habitual action keep up the diarrhoea, astringent will be more specially indicated such as the compound tincture of vitriol. I prefer however, the cornus circinata to all other articles C. servicea (red [illegible]) C. [illegible] C. alba nearly allied Of astringent vegetables we can make choice from a great variety which are indigenous & common. All the various species of viburnum all the [potentillas] & the roots of the strawberry to say nothing of the bark of the oak & indeed most of our forest trees, are astringent & may be used The spiraea tomentosa is much used in decoction or extract All the species of [illegible] are astringent & the C. [rivale] is a most valuable article; as is also the geranium maculatum, which may be be given in wine & then we shall have red wine. The sttici limonium (marsh rosemary) is not so agreeable but is frequently more efficacious specially if the mouth is sore. Its taste resembles that of salt mud. When given internally, it is boiled sweetened & has a little wine or brandy added. It is also used as a wash in case of the supervention of aphthae. The erigeron canadense, called colt’s tail & strangury weed has been found a valuable article in the latter stage of this complaint and of dysentery given in decoction. It is acrid pungent like [illegible] bitter & stimulating & acts also upon the kidneys as a diuretic. It seems likely to prove a Give it in decoction or in milk which will cover the taste of it Balsam of copaiba or turpentine cannot be combined with mucilage so thoroughly as in the white pine bark in milk & water diuretic & [sheathing] to the bowels I have often used the expressed juice of spearmint as in diarrhoea q.v. It is important in long continued bowel complaints of children that the medicine shd be grateful The diuretics are useful both in children and adults (dysentery diarrhoea & cholera infant) because there is a paucity of urine and acrid irritating secretions In some cases of exhaustion we give opium constantly in small quantities to keep up the [illegible] Mucilages marshmallows or substitutes for which hibiscus palustris hib. syrica hib. [illegible] hib. (rose of [shora]) Mucilages by stopping irritation are diuretic 52 a valuable article in the latter stages of bowel complaints provided there is not too much vascular action. It has been long used, vide Barton, the N.Y. Medicophys. Transactions etc. In 1790 an itinerant came through N. Haven offering to cure the dysentery; and attracted a good deal of notice. It was found that his [illegible] consisted of this article. The other species of erigeron have similar properties. In the latter stages of the diarrhoea mucilages should be given. They made of any of the various in articles in use, but perhaps the most valuable mucilage, will be that made from the inner bark of the white pine, which will furnish a terebinthinate principle in addition to its mucilage Often in the latter stages of the disease, great benefit will result from supporting the abdomen by a bandage and a plaister of white [diachylon] and opium or a soap plaister (of [illegible] & soap) 2 parts sp. 4 pts plaister In extreme exhaustion & debility from the long continuance of the complaint with cold extremities, aromatics and stimulants may be required & we may give spiced tea spiced wine or brandy in small quantities, or the white decoction and apply cloths dipped in brandy to the abdomen & to the extremities Nothing has more affect upon complaints of the stomach liver & bowels than the state of the mind as we see in dyspeptics The We are apt to suppose children not subject to notice of [illegible] children [illegible] mental impressions. When the matter has been dissolved in grief & abandoned to despair I told them to tray as a last resort carrying the child in a hack out of town the excitability was entirely gone the child might as well die in the back as any where strange advice On the top of the [illegible] about two miles out lifted up the child [sound] trees grass birds, etc. opened its eyes before this had lain with eyes half closed noticing nothing 53 Finally when every form of medication seems to fail, our only remaining resource will be change of air. This is a most powerful remedy. The physicians of N. York and Philadelphia are continually recommending it. We are apt to suppose that in children it can be only the purer air & the exercise of travelling that produces a good effect, when they are carried from home for their health, but on the contrary the change of scene seems often to have a more powerful effect upon them than it would upon adults. Children that have lain sick for weeks, instead of pursuing their accustomed amusement even though mere infants seem of ten to settle into a state of utter despondency from long confinement & the constant sight of the same unvarying objects around them, & appear to loath every thing offered to be done for them. This morbid condition of mind seems to be one directly opposite to that of nostalgia or homesickness & is to be relieved in a corresponding manner. I well recollect a child apparently in articulo mortis cold & vomiting nothing wd [illegible] the vomiting entirely beyond the influence of medicine or food. It was carried in a hack to the top of a hill without the town N.Y. [illegible] where it had a view of the sound, & the scenery of the country around. While there is brightened up vomiting ceased and took food staid an hour or more & then was carried back to town, where it finally recoverd. 54 The symptoms attending cholera infantum very very much and give rise to considerable variety of practice It is probably owing principally to this circumstance more than to any other that physicians differ from each other in their mode of treating it. Post mortem examination show that this disease affects principally the mucous membrane of the stomach & the small intestines; rarely the large ones. Sometimes coagulable lymph is found in the intestines but less frequently than in other diseases. Sometimes the mucous membrane of the intestines is thickening & according to Dr Jackson ulcers are occasionally found both in the small & also in the large intestines. The liver is usually enlarged without derangement of structure Ordinarily the brain exhibits no morbid appearances, unless the disease has made a determination to that part constituting hydrocephalus N.B. The remarks upon asclepias tuberosa introduced under the Head of [illegible] capitis probably belonged here Fever of the bowels Acute [illegible] of [illegible] Different writers give different names and do not always give the same symptoms. The European disease differs somewhat from ours. It is our infantile winter epidemic. Typhus infantum of Prof. [Tully] “Disease of the bowels bowel complaint, plague of the bowels, winter epidemic & [illegible] epidemic. Remittent bilious fever (at south) Musgrave’s spurious [illegible] fever Duncan III or IV” There is some [illegible] action but more of the character of irritation like other infantile fevers Rarely vomiting never diarrhoea in commencement The morbid excitement often extends to the lungs putting on the for [illegible] what is called in adults bilious pleurisy The disease is not common at this time though it was very much so formerly Probably it will return It is almost the only winter infantile disease & so common has it been also that the nurses call almost every disease in winter, of childr, by this name of choler. The dis. is to be broken up in its [illegible] by means various in various patients by a strong impression upon the stomach in a strong constitution but by an impression upon the whole system in the delicate constitution Comparison to a weight upon a [illegible] If applied upon one part only it will break it not if applied to [illegible] It is desirable that vomiting or at least nausea should talk place from the cal. In enteric 55 Constipation with Fever or Remittent bilious fever of children Musgrave’s spurious worm fever marasmus acutis This complaint has been known in N. Haven for more than 50 years by the name of choler. It is called in some places at the “It is unfortunate that we have no better [illegible]” eastward, the plague in the bowels. It is a common bilious “It affects however the duodenum & small intestines rather than the liver” fever produced by causes which operate upon the bowels a part of the system which in children more particularly invites Children are attacked by it from the age of 3 mo. to 2 or 3 yrs. febrile action. It is often inflammatory in its commencement Sometimes it [illegible] in the form of typhus Symptoms The pulse in the commencement of the disease is full, frequent & sometimes tense, the skin is hot and dry face flushed, respiration, short and laborious, tongue covered with a white fur, the abdomen fuller and harder, than in health, & the bowels costive; the urine small in quantity and high coloured & sometimes the fever is attended with cough & expectoration. This disease is a fever which often affects the lungs and always the alimentary canal & liver, the secretions being suspended and the bowels constipated. Treatment. This will be antiphlogistic in the commencement of the fever & the first indication will be to evacuate thoroughly the stomach and bowels. This will best be answered by a single dose of calomel of from 5 to 10 or 15 or even 20 grains for a child from four to twelve months old We shall thus produce a strong impression upon the whole alimentary canal & upon the system at large. In entonic cases and vigorous habits a little tartar emetic may be added to the calomel Usually the calomel excites both vomiting and purging, but sometimes it is retained on the stomach and has no immediate cases it may be beat to conjoin tartar emetic for this purpose. Sometimes the cal acts upon the stomach & duodenum & excites the action of the liver, and spends itself there, without producing catharsis Sometimes it is necessary to repeat 10 gr doses of calomel once in 2 hours until 40 or 50 gr have been given and cause them to follow with liquid cath. a [illegible] or jalap or scammony N.B. If there is great difficulty in giving medicine repeatedly, we may give powder of jalap in coffee or fermented liquor or we may give a teaspoonful of the tincture of (not briony root but pure jalap in milk & water which will not be tasted Feeble constitution must have the warm’ bath. # Rx senna zjs man zi senega zii anise seed zis liquorice zfs [illegible] ½ [illegible] This I have held the child with. remember large doses are needed Rx scamm. grs 2 or 3 chalk & diaphoretic antim. this was called Earl of Warwick’s powder & was kept in the shop here. Tart. emet. would be a more certain prop. of art. It produced violent vomiting. Scammony is better united with cal. however. # # Cautiokn about covering the [illegible] with a blanket vide # Cal. was finally substituted for the [diaph.] ant. This Warwick’s powder used to be a shot preparation in this town and parent would send for it. From the uncertainty of the strength of the diaph. ant. however, [dangerous] vomiting sometimes occurred from the use of it 56 effect. In the latter case a second dose may be given two or three hours after adding from an eighth to a quarter of a grain of tartar emetic for a vigorous patient Fifteen or twenty grains of calomel will often empty the stomach and bowels freely & remove all the symptoms. The calomel may however evacuate the bowels but partially & in some instances not at all merely moving the contents of the small intestines into the large ones. In such cases another cathartic is needed for completing the purgative operation If the calomel appears to have no effect, it should be repeated in 5 gr. doses every three or four hours, the patient put immediately into the warm bath & we should commence feeding the child as freely as the stomach will bear with the following R fol. sennae zfs, mannae zi steep in ½ pint of boiling water & if there is a cough, add senedae zii & rad glycyrrizhe zfs. If the stomach will not retain the mixture of senna the powder of jalap or scammony mixed with tea coffee or milk must be substituted, giving 4 or 5 grains in the intervals between the doses of calomel Injections vide p. should be given to assist the operations of the cathartics and repeated every 2 or 3 hours until the bowels have been thoroughly evacuated taking care however not to commence with injection until the cathartics have had time to operate When we have succeeded in procuring stools we shall find them to consist of viscid green mucus mixed with half digested food. Sometimes in the progress of the disease they exhibit the appearance of small pieces of membrane, of There is a membrane [illegible] inflammation of the duodenum similar to that of croup. This indicated by pieces of membrane preceded however by pain in the part obstinate constipation etc. This is a strong indication for calomel which however will not operate as a cathartic until the violence of the disease is broken Warm bath & injections will also be more particularly In some violent cases of the fever where calomel seemed to have no effect. I have known acid as lemon juice advantageously combined with calomel Among the cathartics and laxatives used in the second stage we have the wild liquorice or [illegible] [circa???] which was formerly a popular article and kept in families. It is diaphoretic and laxative and possesses and also deobstruent properties It is said that with this the Indians formerly [died] their porcupine quills # The acids are sometimes used in combination with mercurials I should not use them unless when mercury fails Sometimes it affects the ear & produces suppuration & discharge. It may terminate in effusion into the ventricle of brain. It may terminate by exhaustion Or may terminate in thrush “in which case there is a double translation 1st from the bowels to the head & thence to the mouth oesophagus & bowels 57 & of about the size of petals of peach blossoms, floating in a liquid of the same colour. Such stools as these latter are a sure indication that a farther evacuation from the bowels is needed vide p. 207 They are frequently evacuated by adults in bilious (or common cholic. If such continue it is well to vary the cathartic and give magnesia, or soluble tartar (peerlash & cremer tart.) or phosphate of soda, or any other neutral salt. generally the violence of [illegible] [illegible] & The blue pill may be substituted for the calomel & given three or four times a day, until the stools change their appearance or the mouth is affected, though this rarely happens to children under four years of age. These stools rarely have any smell & as they indicate a want of secretion I the liver & glands of the abdomen, mercurials are peculiarly appropriate. In some states of fever attended with stools of this kind I have known the free use of acids with mercury very useful # After 48 hours the fever generally remits, and sometimes it continues in the form of a remittent for six or eight weeks or more. Very frequently however it changes its seat in the course of 15 or 20 days & terminate in a phlegmous swelling of some of the glands or in phlegmon or is determined to the head & puts on symptoms of hydrocephalus, which are best relieved by blisters behind the ear, a place which is the natural outlet of diseased action in children. They may terminate naturally by a discharge of purulent matter from the cavity of the ear or fatally by effusion into the ventricles of I recollect two cases early in my practice, which continued 6 or 8 months. They were very violently attacked They continued 6 or 8 months coma Hence we should never despair In the latter stages it may be proper to give tonics or those articles which are called tonic very unlike the vegetable tonics however. They produce a [illegible] excitement Giving arsenic is no new practice It is a safe and efficatious remedy, when the dis. continues as a remittent It comes after cal. & tart emet. producing liquid secretions. If long continued it must be followed by bark to restore tone and obviate the debility caused by the arsenic Arsenic can only be called a tonic as it removes disease. It would never be given as a [illegible] is pure debility # # I have used digitalis, in the latter stages to allay irritation # In many cases the fever continues from habit & medicines have little affect. There will be an accession of fever every afternoon. Here give sol arsen 2 drops twice a day which is a full dose for a child ½ years old If this has no effect give it [illegible] times a day” 58 the brain; in two cases I have known them relieved by a thrush. If the disease continue a regular remittent without symptoms of hydrocephalus, it will be proper to give tonics, such Moseley’s tonic solution or if the fever intermits or remits Fowlers solution of arsenic the latter in doses of two or three drops the former from 4 to 20 drops, 3 or 4 times a day. I have known a child 18 months of age cured in this stage of the fever, in the course o f two or three days by taking 2 drops of Fowler’s solution 3 times a day. This article however is liable to produce edema or dropsical effusion & if it does we must substitute the tonic solut. (beginning with about four drops) or some preparation of bark. The dose of the tonic solution will depend upon the irritability of the stomach If irritable from 3 to 6 drops will be as much as can be borne After the inflammatory action has subsided narcotics anodynes are necessary to remove irritation and to procure rest We may use opium, either alone or better combined with ipecac or antimony # Indeed as the skin is usually dry antimony is indicated in almost every stage. The warm bath also is indicated in every stage except in the low typhus state of the fever when it would be too debilitating. Epispastics & irritants are useful in the progress of the disease, to translate action from parts essential to life & in the last stage also perhaps to keep up the action of the system. They may be applied to the abdomen if it is much swollen to the head behind the ears where there is danger of hydrocephalus & Avoid too much heat to prevent tumefaction of the bowels. Terebinthinates a [illegible] oil may be needed proper If pneumonic symptoms blister etc. “If the lungs are much affected, apply a blister to the chest, give expectorants, and pursue the treatment required in pneumonia. Senega & squills are good, but are too stimulating for the earlier stages liquorice anise” By this disease it is sometimes proper to do nothing and omit all medicines in mania etc. In those cases as I have had difficulty to persuade parent to do nothing. I have applied aloetic plasters to the bowels I think they have produced evacuations injections also can sometimes be given Case of a very [illegible] child [furious] parents passed in review before him with roasted apples pears etc. after 26 hours he snatched an apple relapsed in 26 hours they probably had over loaded his stomach however the same management finally succeeded afterwards of the patient recovered. vide p. [20?] The same season I had 3 or 4 more such cases of mania which required to be cured by fasting 59 a large one to the chest if the lungs are affected. “This disease is sometimes followed by thrush when an emetic of ipecac will have a good effect. If the stools are fetid charcoal should be given. If in the latter stages there should be tumefaction and pain in the bowels, the abdomen should be supported by a bandage. In the latter stages also a decoction of the inner bark of the white pine be useful. It possesses some tonic properties” Sometimes in diseases of children the mind is affected, the patient will take neither solids nor liquids & struggle till it is exhausted whenever an attempt is made to administer any thing. If that is the case in this disease we must use the tepid bath & we may a apply for purpose of moving the bowels, a large plaister of aloes and ginger to the abdomen Frequently this derangement & morbid revengeful disposition (according to Dr Rush an affection of the moral faculty is so great that we must wait even for 24 hours or more without administering any thing. It may require great prudence and judgment in such cases, to satisfy the parents. Before leaving the subject I may observe, with respect to the propriety of the course I have directed in the commencement of the disease, that if the cathartic which we administer first produces emesis we may be sure that the alimentary will be operated on, & also that we often require a remedy more powerful than the disease, just as in croup. “As to diet meat must be forbidden but sometimes salt food is craved. The weak chicken broth is good. The dis. is something very rapid & violent Fever as violent as the constitution could bear Collapse from the violence of action Parents considered the patient & dead After the mustard was applied as soon as the skin was reddened a blister was applied, which produced a sore 2 or 3 months in healing “In one hour pat. revived” Nervous system affected Irregular action such as after collapse of cholera Strong clonic spasms once in 15 min. “Pat. kept under a constant [narcosis]” Antispasmodics & tonics finally In two or three weeks [illegible] recovered some strength It was called the child that died & returned to life again The above is account of the disease as it most commonly appears. It is different however in different years sometimes effecting one part of the system sometimes another A practitioner keeps this [illegible] [illegible] 60 Case of a female child 2 yrs of age. The disease ran the most rapid course I ever witnessed. The whole system became affected; the pulse was full & frequent, the skin hot & the tongue furred. In 24 hours the disease came to a crisis and exhausted the excitability of the system; the pulse grew faint, the skin cold and the respiration languid the patient became insensible & was apparently dying sinapisms were applied to the abdomen, ankles & wrists & heated bodies put into the bed, to restore warmth. After the sinapisms had been on an hour and excited some redness, epispastics were applied in their stead. Ammonia & ether were put into the mouth & caustic ammonia was applied to the nostrils to excite Inflammation so as to blister. Ether was also put into the mouth In about two hours the system was resuscitated. Immediately a train of most violent nervous symptoms followed the chill became convulsed almost instantly. After trying antispasmodics in vain the convulsions were checked by laudanum, 6 drops, every two hours. The laudanum lost its effect in two hours & needed to be repeated. The blister on the chest produced a deep ulcer which was difficult to cure Finally tonic solution was administered. The child recovered Child of Mrs “Moulth???] Child of N. Beers’s vide p. 208 diseases and consequently meets with no new disease For they do not make sudden transition as in botany plants he is guided by symptoms & by the operation of remedies Appendix to Mes. fever acute marasmus This disease sometimes appears in an acute form with great irritation Sometimes terminates in hectic Patient will run down very rapidly [illegible] appearances enlargement & [illegible] of mesenteric glands “Called” consumption of the bowels” or Marasmus” Mesenteric fever is thought to terminate in hectic Probably it does especially in scrofulous patient and in those bad cases where the tubercles with a mesentery ulcerate “The pain in the bowels is no usually very severe but of a continued aching kind generally better removed by [camomile] injections than by anodynes” 61 Mesenteric Fever Marasmus tabes [illegible] [illegible] This disease arises from obstructed glands in the mesentery & is accompanied with morbid secretions of the stomach & liver bowels. It is sometimes the consequence of some other fever. It is often connected with scrofula, & it is apt to be attributed to worms. The disease attacks children of from two to ten years of age. Symptoms. The fever is of the intermitting remitting kind, with irregular paroxysms attended with tumefaction of the abdomen, costiveness, indigestion, loss of appetite & very irregular appetite & with paroxysms of pain in the bowels. The patient complains much of its bowels, but the affection seems to be rather distress then sharp pain & is neither constant nor regular. The countenance is very pale except when the cheeks are flushed with fever & the limbs are emaciated This is generally a chronic disease, but sometimes it is acute, & exhibits strong marks of irritation in the system. It may terminate in hectic. Dissections exhibit an enlargement of the mesenteric glands. Causes. It is sometimes as has been said above, the effect of another fever. Among the poor, with whom it is most frequent, it is caused by coarse and unwholesome diet. Children born of scrofulous or gouty parents are more subject to it & hard labor by the mother during the period of gestation may have some influence in predisposing to causing this disease in the child. Patients in this disease are subject to paroxysms of pain 62 The indications are 1st to empty the bowels and to keep up a gentle peristaltic motion in them 2nd to change the secretion of the chylopoeitic viscera. 3d to remove paroxysms of pain 4th to remove the obstruction in the lymphatics. 5th to impose the digestion & to invigorate the system generally 1at To move the bowels and keep up a gentle peristaltic motion mild mercurials as blue pill or calomel & chalk should be given & at the [illegible] time friction as in almost all chronic [illegible] complaint should be employed, upon the abdomen, and persevered in by the attendants. A very good mercurial preparation, will be a pill of four parts gr. blue mass and one 1 or ½ gr of ipecac adding a little opium ½ or 1/8 gr of the bowels are very irritable. If this preparation is not sufficient calomel may be substituted in a dose of 4 to 6 grains. The tincture of rhubarb has in some cases answered well as a laxative & corrector combined with neutral salts and aromatics 2nd For changing the secretions, we must rely upon the articles just mentioned, and also upon those to be mentioned under the 4th head 3d For alleviating sudden paroxysms of pain injections of a gill or a half pint of camomile tea have been found serviceable. If these fail give a camphor injection The pain is relieved by opium plaister There is but a small quantity of iodine and [illegible] effect appears to be produced than shd result from the small quantity of iodine Neutral salts in connexion with tonics have undoubtedly [illegible] deobstruent powers 63 4th For removing obstructions of the mesenteric fluids burnt sponge has been thought very efficacious. I formerly questioned whether it had any superiority over soda. Now it is supposed that all the virtues of the article are owing to the iodine continued in it. It would probably be [illegible] better better to give tincture of iodine in doses of 2 or 3 drops. Still the burnt sponge containing carbon & alkaline matters may have peculiar properties The neutral salts given with tonics have some influence in removing these obstruction It has been proposed to use mercury by injection for this purpose. I know not that it has ever been tried For the indication I have been in the habit of employing the muriate of lime & here given it in connexion with the mercurial pills mentioned under the first head It may be made by adding muriatic acid to chalk or marble & the dose for a child of 3 or 4 years, should be from 5 to 50 drops, given in tea coffee or milk. It is best to begin with a small quantity, say 3 drops & increase by one drop at every dose until the stomach is offended remembering that the stomach bears the article best if much diluted. The muriate of barytes might be used; also the carbonate of barytes is used in dose of but 2 or 3 grains, it being a powerful article. But iodine is probably the best article that we know of Other articles containing iodine, have been used besides burnt sponge, as [fucus] [nodasus] & vesiculosus [reckoned] vide scrofula mur. [illegible] dose 4 or 5 drops in milk & water for a child of 3 or 4 years increasing to 50 even 100 perhaps This [illegible] is not to [illegible] [illegible] it iodine as to be substituted by the latter We are apt to neglect an old remedy as a new one comes on The tepid bath shd not be used when the system is too much debilitated It excites the action of the mucous membrane and of the skin not affecting particularly the blood vessel add a little spirit to make the opium [illegible] if necessary 64 Muriate of lime has the important advantage of exciting the action of the skin which is generally torpid. Hence also the tepid bath has been used with success in this disease The flesh brush too if thoroughly applied several times a day will have a powerful effect. 5. To improve the digestion and invigorate the general system Carbonic acid is a most grateful stimulant to the stomachs of patients in this disease. Hence soda water and other effervescing mixtures, may be recommended spruce bar also & similar articles, if they agree well with the stomach. Aromatics as ginger & spice may often be added to them with advantage Among the tonics which are used to invigorate the system. Iron is very often employed & frequently with good success. The mildest preparations least irritating are the best, such as the tincture of the muriate, the martial flowers & the alkaline solution. Still iron is apt to cause irritation Cold bathing is a good remedy for invigorating the system but if the patient is much debilitated, a cordial should be administered previous to using it When the patient is much debilitated I have found anodyne plaisters upon the abdomen give great relief (where opium did not agree) I have used Noel’s plaister (similar to dyachylon) with soap mix opium zii with zfs of this plaister & spread it sufficiently large to dover the whole abdomen Children are very fond of potatoes but they should not be allowed, unless cooked so as to be dry and [illegible] and then thoroughly mashed Some vegetables as spinach, [illegible] & asparagus may be allowed but only in moderate qualities Preparations of meal of [illegible], especially fried, are bad Rx dough roll it in flour and then cut into thin slips, twist & bake them for [some] hours An excellent preparation for dyspeptic batter than crackers called twisted bread In making broth avoid adding rice, flour, etc. which will make the compound approach the nature of pastry and be more indigestible. Make broths as simple as possible & season with pepper & salt 65 Under this head may be ranked the use of the terebinthinates which have a valuable effect upon the mucous membrane of the alimentary canal The best article is a decoction of white pine bark, which is milder than any preparation of the turpentine of the shops Regimen. Flannel should be constantly worn next the skin to keep up an action in it. The patient should take exercise in the open air whenever the weather is good & damp easterly winds should be carefully voided as they have great influence in all chronic affections particularly glandular of the bowels. Friction & cold bathing have been already mentioned. Diet. This should be carefully attended to Raw fruits, potatoes and other garden vegetables, corned beef & in short all articles which are not of the easiest digestion or which have any tendency to ferment & become acescent in the stomach should be forbidden & caution should be enjoined that the stomach be not distended with liquids, so as to interrupt digestion. The diet should be dry consisting of toasted bread & farinaceous vegetable substance, as arrow root etc. well boiled & seasoned with a little wine & spice. If meat be given it should be broiled & eaten, with condiments. In some cases a piece of lean beef that has been partly broiled & then boiled, makes a broth that is grateful & sits well on the stomach. But if there is much dyspepsia, broth of any kind a not good If this fever terminates in hectic the mineral acid shd be used Undoubtedly however the affection may be produced by excessive purging vide next page low states of fever in adults also for the state of the bowels occurs much oftener than some phys. are aware of “The gases may arise from the ingestion, from a fermentation of the natural secretions, or, as I think from a direct secretion of gas by the intestines. this alone would see to account for the rapidity of its production” sometimes small watery stools 66 Tympanitis In diarrhoea dysentery & constipation with fever & typhus fever after these diseases have passed the first stage, the bowels of children affected with them, are liable to be affected with tympanitis. a troublesome symptom This state of the bowels may occur of itself about the time the febrile action begins to subside, or it may be brought on at an early period by the use of astringents, or by heat produced, either by too many bed clothes or by hot articles applied to the body for the purpose of exciting perspiration it is important to examine daily the state of the abdomen in children affected with bowel complaints, that a tympanitic state may be obviated, as soon as it begins to appear The abdomen is [swollen] and elastic to the touch feeling tense like a drum head under the fingers We can tell as soon as the hand is applied whether the swelling proceeds from inflammation, or from imprisoned air, for in the former case the pressure will cause pain The proximate cause of this state of the bowels I believe always to be a relaxation of the villous coat of the intestines & a deficiency of peristaltic motion in consequence of both which the villous coat falls down & forms a valve which confines the gas, while at the same time there is a morbid secretion of all the chylopoeitic viscera which [illegible] the evolution of the gas In the first stages of tympanitis, the alvine discharge usually cease even if there had been diarrhea & dysentery before & the little patients exhibit signs constant [illegible] not acute pain of great uneasiness from the unusual distention of the “It is thought by some that tympanitis is always occasioned by bad treatment in not giving cathartics enough at the common [illegible] Such persons probably do not examine the abdomen of their patients with sequels of severe bowel complaints. Tympanitis comes on whether cathartics have been used or not and nothing is more likely to bring it on than an excessive of cathartics at the commencement of the disease” The temperature had been raised above it secreting [illegible] & the child might have died “I am very partial to diaphoretic measures in general but must confess it is often abused If carried to excess it rapidly exhausts the patient also if excessive heat as aplied and the pat. does not sweat.” 67 bowels. In the progress of the disease tympanitis the child frequently comatose. The tympany is not always to be regarded as a dangerous symptom it sometimes indicates a favorable crisis, yet if it is accompanied with coma, there is danger that the brain may become seriously affected. If symptoms of congestion in the thorax exist, the disease of the thorax should claim our first attention, and the tympanitic state of the bowels be treated as a [illegible] complaint Treatment. The indications are to evacuate the flatus and excite healthy action of the viscera of the abdomen If the disease has been produced or aggravated by heating applications too many bed clothes or too confined an atmosphere, the heated substances should be removed, the bed clothes thrown off & air admitted freely to the patient. In the summer of 1814 I was called to a child sick with dysentery whose bowels became extremely inflated in consequence of filling with the steam of boiled potatoes in [illegible] the bed in which he lay The child because if much [illegible] & [illegible] was so difficult that it was thought to be dying; but upon removing the potatoes throwing off the bed clothes & opening the doors, the symptoms were at once amended & in the end the disease was completely removed by the use of a little [cajeput] oil in water and laxatives For removing the flatus of the bowels we may use enemata of the decoctions of aromatic plants or suds, such as catnip, camomile; the seed of fennel caraway or masterwort seeds or the essential oil of such suds may I prefer camphor to any other articles 3 or 4 [illegible] IN colicky complaints etc. I have known more benefit [illegible] injections of camphor in milk & water than from any [illegible] articles and that too after the most violent purgatives had vailed. I know of no article which operates so well in relieving irritation of the pelvic viscera [Anodyne] balsam Rx vol. [lin] zi [illegible] camph “Sometimes blister the abdomen” 68 be injected in milk and water. But I think I have experienced the greatest benefit in the case of children from the injection of a teaspoonful 2 or 3 of the tincture of asafoetida in a gill of warm water. It unites more readily with the water of a little milk is added A pipe of ivory or the pipe of a common injecting syringe may be introduced into the rectum as is recommended in hysteria, for the purpose of evacuating the flatus. I have sometimes used an elastic catheter with success The peristaltic motion of the intestines is to be excited and healthy secretions induced For this purpose we are to apply friction with dry flannel to the abdomen and mild cathartics are to be given. The latter may be jalap aloes rhubarb etc. with castor oil to work them off If frictions do not succeed, we may apply volatile liniment camphor, oil of origanum & finally epispastics We may likewise give internally cajeput oil in 3 or 4 in sugar oil of mint, oil of caraway, asafetida zfs to si etc. which is [illegible] to offer [illegible] its stomach & is not offensive to the taste and magnesia with [illegible] & cubebs [illegible] [illegible] or guaiacum Dr Good classifies [worms] according to their locality yet he makes mistakes as to their locality Much has been under the subject, and the remedies are almost innumerable. It is rather difficult to select the most important parts of the subject 69 Worms This subject naturally follows that of bowel complaints From testimony which cannot be invalidated it appears that worms of various sizes and forms have been found in almost every part of the human body. It is only in the alimentary canal however, that they occur with any frequency and give rise to symptoms, from which we are led to infer their presence Those worms which are of anomalous kinds, or are found in anomalous situations (oftenest perhaps in the lungs & frontal sinuses) as they are of rare occurrence & as the indications of their presence were either very obscure or altogether unknown wanting are interesting only as curiosities and will be passed over, without any notice, except an occasional reference to the fact known with regard to them “Worms in the alimentary canal are so common, as to have given rise to a class of diseases called verminous & a class of therapeutic agents called anthelmintics. The kinds of likewise of worms which occur in this part of the body have been thoroughly investigated & we are in possession of a large mass of information upon the subject I shall consider this subject under the following heads 1st The kinds of worms found in the al. canal 2nd their origin & that of worms in general, found in the body 3d the general effect they produce on the system & the general symp 5th the morbid effects produced by each species, with their treatment 4th the general treatment of verminous diseases 70 II. The genera of the common intestinal worms are three; toenia ascaris & tricephalus Of the tania there are two species. Tania solum or cucurbitana & t. lata or vulgaris. Of the ascaris there are also two specis of a. vermicularis & a. lumbricoides. 1st Tania This a long flat worm varying much in breadth and thickness which is formed by a chain of flat articulations, united by a border or edge. The accounts of the length of this worm are almost incredible from thirty to a hundred feet. Taenia solum (called also cucurbitina or gourd seed worm & the armed taenia) is distinguished by having the head forked and surrounded with papillae or long fangs (holders) by which it fastens itself to the mucous membrane. The broken off joints have when discharged the appearance of gourd seeds. hence its name of gourd seed worm. Taenia bata (or vulgaris the unarmed taenia) has an external form like a ribbon joints scarcely perceptible & is white and seen transparent. The head is narrower & smaller & the papillae not elongated 2nd Ascaris vermicularis & a lumbricoides The first, a. vermicularis (thread worm, pin worm & when existing in number called ascarides) is filiform, slender at both ends & from half an inch to an inch in length & of the diameter of a small thread found generally in the rectum & though not confined to that part of the intestines. It feeds on the mucus of the intestines & produce its young in immense quantities. It is found in the stomach & called maw worm 71 Ascaris lumbricoides (or [illegible] long round worm) is perfectly round & from four to ten inches in length bearing a striking resemblance to the common earth worm It is said sometimes to perforate the intestine with its mouth 3 The trichocephalus now called [tric???] is a small capillary worm from an inch to an inch & a half or two inches in length. The body is about half an inch in length & Is terminated a tail which is twice as long & end in a fine hair-like point In addition to these worms have been reckoned two others the vesicularis & the gordius. The former is a small vesicle found in the brain (sometimes in great numbers) & containing many small worms. It is now considered a hydatid & is excluded from the subject of worms & verminous diseases The gordius (horse hair worm) is found in soft stagnant waters from four to six inches long & twisted into various knots & contortions” Good. They are sometimes found in the earth in great numbers they turn black on exposure to the air & resemble horsehair, hence their name of horsehair worm They are very common in our vicinity They are rarely found in the human stomach. I have known them coughed up in abundance from the lungs; when they had probably come from an abscess in the liver. It gives rise to a severe disease among the [lapladens]. Vide Good. The maggots of the common house fly & the’ larvae of many other insects, have occasionally been met with in the alimentary canal of the human body vide Good What were formerly called vesicular worms are now considered as hydatids. [Brera] or worms recommended An attempt has lately been made to revive the doctrine of [equivocan] generation. The learned advocate has attempted to fortify his opinion by the analogy of vegetables. But where the experiment has been made the seeds of the forest trees that come up as [illegible] may be found at the roots of the young trees Hyoscyamus formerly was common here but is not now However when the gourd is broken in the college yard Hyoscyamus springs up. It has also in the soil brought from a cellar in Chapel St. Leeches & a variety of insect are undoubtedly taken in in water etc. In Duncans [illegible] we shall find an account of a number of caterpillars [illegible] by a child produced by eating cabbage leaves I think I have never known an instance of worms in children while nursing 72 II II. The origin of worms in the human body Worms arise from eggs. Some multiply by depositing their eggs to be afterwards fecundated by the male. Others are propagated by copulation between the two sexes While a third kind of the taenia fecundate themselves. I have spent much time in investigating the origin of worms in the human body but must confess that I cannot satisfy myself upon the subject. It has been supposed that worms found in the human body are produced from eggs deposited by flies about the rectum, at the time of going to stool. Were this the fact, they ought to be more abundant in summer than in winter, while the reverse is the fact. I am inclined to think that the rudiments of worms are contained in certain kinds of food as apples pears, cider water & unboiled fruits and vegetables. In infer this from the fact that worms make their appearance, oftenest when such articles have been taken & disappear when they are avoided. If confirmation of this view of their origin we find that children are rarely if ever affected by then when under three months of age & seldom while they are nourished from the breast. For though some have asserted that they have seen worms in the bowels of children within the mouth & even before birth yet the fact is not well ascertained. Breras opinions, also adopted by Good speaking of the fluke worm There is no doubt of the fact of worms within [fetus in uteri] 73 Brera thinks that the minute eggs of worms are absorbed into the circulation He says “when we consider that the eggs of worms are so small that they are not perceptible by the microscope of Hoffman and these eggs themselves are masses of small eggs, nothing is more probable than that the eggs of worms are absorbed by the lymphatic vessels, pass in to the circulation pervade the system with the blood & are deposited in the various parts of the body, where they enlarge and unfold themselves when circumstances favour their development.” If worms are found in the foetus, the fact will favour this idea that the eggs of worms are carried into the circulation. It may be remarked also that the parts of the body which favour the development of their eggs are those abounding with mucous The hypothesis of equivocal generation is neither specious nor probable. It derives no support from analogy aid from reason, nor countenance from fact In its operation it is worse than useless as it tends to obscure truth by substituting conjecture while it disregards with the most vague and licentious imagination the boundaries between the animal and numeral kingdom & ascribes to chemistry what pertains only to animal life When the creator first gave being to the natural world, every part of the vegetable and animal system was brought into existence by an extraordinary exertion of productive power. They were not moulded by the slow operation of time & the cooperation 74 of mechanical and physical forces, but he spake and it was done. But since that first act of creative power, we find are that these creatures are propagated and perfected by processes more gradual successive and [operose], many of which may be traced by human wisdom and admit of being regulated and controlled by human culture & ability Rosenstein says “from the eggs of a fly proceeds a fly, from the egg of a hen a pullet and not a serpent, from the egg of a goose, a goose and not a fish So from one worm is produced a worm and nothing else” II II II. The effects of the presence of worms in the body When the seed of worms are once developed in the human body, the health is more or less affected, and the morbid symptoms which then appear are in proportion to the number of size of the worms the sensibility of the part they occupy and the general morbid diathese which takes place at the time, whether the cause or the effect of the worms Worms in the alimentary canal are less frequently the original cause of diseases than is generally supposed, inasmuch as in many cases of disease where they exist, the disease was merely aggravated & not originated by the worms & all the symptoms of worms from which it is common to infer their presence, may be occasioned by 75 undigestible substances for a diseased state of the bowels Worms are often also found to have existed & that too in great numbers, where the general health has been apparently good. I well recollect the case of a child in North Milford who fell from a height & was taken up in a state of coma from the concussion. A dose of calomel was given him which brought away twenty or thirty large worms. The child had been healthy to all appearance previous to the accident. Some physicians go so far as to say that worms are necessary for the health of vigorous children that they are nature’s scavengers a natural provision to destroy the superabundance of food taken into the stomach. Dr Rush was of this opinion. The opinion supported by Dr [Parr] It is a fact beyond controversy that very healthy children have worms with out manifesting any symptoms of their presence until the supervention of some other disease causes them to make disturbance in the system. It is but seldom that they are the excit. cause of dis. The following are some of the ways in which worms are injurious to the system. They may be injurious from their number obstructing the bowels and consuming too much food. They are particularly hurtful by the irritation which they produce when the irritability of the bowels is excited by fever. They sometimes threaten suffocation by rising in the oesophagus & in one instance a single worm I have known to lie in the fold of a volvulus of the intestines so as completely to obstruct the passage 76 Linneus attributed the dysentery to a worm or insect [illegible] dysenterical [languis] the measles to a similar origin. Various authors the itch, sigler, petechiae lusitanus the syphilis martin the elephantiasis nyander, eruptive & contagious diseases in general lancissi, plague, remitting & intermitting fever considering miasm [it] being a collection of insects # some authors, toothache Dr [Adam] observes cancer itself is nothing more than an animalcule a worm or an insect. It would seem from such speculations, that a great part of the diseases which flesh is [illegible] to result from a superabundance of vitality and that as Good remarks in his [illegible] corruption is no longer the triumph of death over life, but of life in one form over life in another. Such fancies lead into the wildest speculations of equivocal generation & relinquish all principles & all limits in natural history. # Vide N.Y. Rep. about the year 1815 77 Symptoms of worms. Those children are most frequently troubled with worms whose powers of digestion are weak. The symptoms of the presence of worms in the alimentary canal are very equivocal, for they may all proceed from other causes. They are countenance pale or flushed sad and dejected livid around the eyes, eyes sunken eyelids swelled pupils dilated itchings in the nostrils, head ache after taking food, mouth water [illegible] filled with saliva, breath fetid, great thirst, grinding of the teeth in sleep, starting in sleep fainting vertigo, palpitation of the heart, irregular pulse & cold abdomen bowels flatulent costive or loose colic throbbing in the bowels severe from [illegible] the small [intestines & umbilicus] appetite irregular & craving loss of appetite pain in the stomach when empty, which is relieved by food urine increased or diminished turbid and milky, stools irregular, containing much mucus nausea & vomiting Sleepiness particularly after eating, bloated countenance swelled nose & upper lip, paleness of the lips, irritation about the mouth, rubbing the nose, itching at the anus irritation about the neck of the bladder dry & convulsive cough difficult respiration sense of suffocation paroxysms of suffocation body emaciated frequent flushings of fever with irregular pulse convulsions, epilepsy and partial palsy. Of course these are not all present at any one time Chorea catalepsy & epilepsy are produced sometimes, by worms Dry convulsive cough Diff respiration In addition to the other symptoms there may be these of irritation of the lungs producing cough also irritation of the brain [772] It will be impossible to class all the articles inasmuch as we do not certainly know the modus operandi of many articles which yet have sustained their reputation for [illegible] Much stress has been laid upon the operation of cathartics in evacuating the [illegible] which the worms generate by their irritation, just as irritation in the lungs produces [illegible]. But then the [mucus] although it forms [illegible] for them, an effect more than a cause, and the worms will make [mucus] enough for themselves Probably many caths act by their acrimony upon the worms themselves. Others by the violence of their operation dislodges them. “Aloes are beneficial in mild cases as a tonic when there is no excessive irritation. If there is excessive sensibility & irritability they are improper as they irritate the rectum they may be given by injection When there are symptoms of worms though no worms exist aloes are serviceable in the form of elxiir prop.” 77:a. IV. [general treatment] In the treatment of patients afflicted with worms two general objects seem to have been pursued both in popular practice & in that of physicians 1st to destroy & expel the worms themselves & 2d to obviate their effects upon the system & at the same time by the improvement of the general health of the patient, prevent their recurrence and increase This second indication will often coincide with the first, inasmuch as a diseased state of the body is the most favorable for the multiplation of worms Of those remedies which destroy or expel the worms themselves we have three kinds 1st those that expel them by strong cathartic operation 2nd those that act mechanically upon them 3d those that are prisoners to them. 1st Although strong & even violent purges may be used to drive out an accumulation of worms in the bowels yet they should not be often repeated as they would increase the weakness & irritability of the stomach & bowels to such a degree as to favour this increase. In general calomel will be the best cathartic inasmuch as it will tend to promote a flow of healthy bile & to restore healthy secretions. In Europe the gall of animals has been administered. One of the best forms for the administration of cathartics is that of alkoholic tincture, for the sake of the joint effect of the alcohol hence elixir proprietalis in teaspoonful doses & the tinct. “The bark of the button wood taken from the north side of the tree has been recommended. It is a nauseous bitter & a cathartic good” # “It is a question whether cowhage acts mechanically or whether it contains an acrid principle like that which exists in the nettle” # One of the remedies that I have most reliance on for ascaride in tinct [illegible]. Fill a bottle with the young inner bark fill the interstices with [prosp] spirit & give I to zfs night & morning It is an old remedy and better than tinct aloes It is tonic & deobstruent” Some of the acids to be narcotic, are more probably active merely by their pungency, odour etc. 77:b. of hickory bark or buds have been found very serviceable Podophyllum peltatum is much used but is probably not better than other cathartics. The best form would be that of a tincture 2 Mechanical remedies are not now used. Cut hair has been given cowhage though some doubt whether the operation of this is wholly mechanical. I have thought that the root of osmunda given in pieces acted mechanically The filings of tin, formerly were much employed as was also an amalgam of tin & mercury. There is a curious account in one of our journals of a man in Kentucky who took a pound of the amalgam & was unable to expel it from the bowels The mass lodged in a part of the intestines & could be felt externally It was very troublesome to him when riding. Oil has been given with the intent that it should fill the respiratory pores of the tape worms & thereby destroy its life. In Madame Nouffeurs recipe The supper of panada is intended to act mechanically by its bulk. 3d The remedies which destroy the worms seem generally to be narcotics All articles of this class however do not have this effect opium for instance. Particular animals are sensible only to particular narcotics as for instance swine are poisoned by stromonium while sheep eat it with impunity. The most valuable article of this class are the two species of spigelia s. [ma??ndica] & s. anthelmia A strange notion has existed about a little innocent [illegible] was considered as the narcotic agent Similar reasoning has been used with respect to denarcotising the opium Opium denarcotised would be not better than bread Spigelia zii in ¼ pt water to a child may be given in divided doses. It is better to give a cath. e.g. cal. or ruhb Spegelia from zfs to zf for an adult Sometimes but rarely it operates itself as a cathartic Sometimes convulsions are produced Our pink is bad because it is gathered by [illegible] packed in hogsheads & the rotten saved & the rest [illegible] The emigrants from St. [Illegible] brought what they called worm syrup which they said shd be given in the night because it affected the eyes S. [anth.] is [illegible] S. [illegible] about zi if S. anth. “Pink is given more especially for the [round worm] & sometimes for the tape worm” [illegible] [illegible] & [areca] [oleacea] zii to zfs “The French use the syrup of peach flowers & seeds They first give sulph either zi in [illegible] decoction male form & an injection of the same. They probably act by their prussic acid” 77:c. The former is the one commonly used in this country and in England It is called Carolina Pink. This is a most valuable article and is useful not only for its operation upon the worms but for its effects upon the system, in allaying the irritation which they occasion. I have prescribed it for a cough & other symptoms of irritation where I had no reason to suspect the existence of worms Then given for its effect upon the worm from half an ounce to two ounces should be given in decoction in the course of the night, accompanied with rhubarb or some other cathartic to drive the worm off while in a state of intoxication. It may be given in powder in a dose of from 10 to 20 grs The French W. Indies s. anthelmia is used & called wormgrass. It is a stronger article than ours The French use the article in form of a syrup & give a teaspoonful at a dose. Veratrum subadilla & helleborus [fetidis] belong to this class and have been given in doses of 2 to 6 grs for children In Europe the most famous article of this description has been the Felix mas Other articles of this class are camphor, prussic acid & tobacco The bark of the cabbage tree (of which there are two species vide Good) is found highly valuable in this way by the West India physicians Other articles which have been said to be successful in cases of worms owe their success apparently to their acrimony in whole or in part, such as the terebinthinate oils Oil of turpentine is the one commonly Various aromatics have been used, as chenopodium [illegible], rue tansy “The leaves of cedar juniper & [illegible] powdered 20 grs They are acrid stimulating and tonic & may have a mechanical action. It might be used to add to the powdered leaves some aromatic as rue ol. tansy [worm] wood etc.” “Melia [azidurach] bark of root or plant zfi to zi act as emetic cathartic & narcotic. Acts more effectually at the south where the recent article is used” 77:d. employed should be given in large doses, when it will prove cathartic. A concentrated solution of salt has been strongly recommended given by the mouth or by injection Ether is much used by the French & perhaps has an effect upon the worms. Some of the other antispasmodics which have been popular may also have some effect upon them such as asafoetida, petroleum the essential oil of the chenopodium etc. Perhaps arsenic poison intestinal worms I have known it cure. Ammonia may perhaps act on them 2 Of the remedies which are designed to have an effect upon the system. In severe affections from worms our first attention must often be directed toward quieting the excessive irritation of the system, by antispasmodics. Various popular remedies for worms seem to have little other virtue The chenopodium anthelminticus & c. ambrosioides called worm seed & the c. botrys. or [juris] oak ar probably valuable, mainly if not entirely a nervine. They may be given in decoction or the essential oil may be used. The garlics are used in syrup or decoction they are nervine 7 have considerable effect as condiments upon the intestinal canal. The ictodes fetidus is of this class & so are the empyreumatic oils, petroleum given in a dose of 10 to 40 drops barbadoes tar etc. For giving tone to the digestive organs and exciting their sluggish action the tonics the bitters & the aromatics are indicated while mercurial [Artemesia] ][santonica] is no better probably than the other bitter tonics Some confusion results from the appellation worm seed being applied both to this and to [illegible] botrys c. anthel. & “Indeed anything which tends to [procure] healthy secretions of the viscera. Of this kind are the mercurial which produce healthy bile which is especially [illegible] to [illegible]” # “Indian corn or maize has been supposed to favour the generation of worms in the body. The aborigines of this country have been peculiarly subject to them perhaps from this cause” Worms are far less common now as are also colic dysentery et. than formerly when cold water & cider were drunk instead of tea and coffee AT the south likewise the negroes who feed more upon crude and raw articles are more subject [illegible] of the plantations it is a rule to give a decoction of melia to the black children once in 3 months # Though you can cure worms generally by calomel yet sometimes they will resist all treatment Eupatrium perfoliatum is used for worms Flowers of [zinc] are antispasmodic so also sulph zinc Dr Rush thought well of [sugar] especially when given in the morning Petroleum seems to be a valuable article a substitute for turpentine It may be supposed dangerous, but I have used it for many years without inconvenience I began with small quantities from fear of danger, but now I give 10 30 or 60 grs It very often to produce no violent effects. Yet we must not conclude hence that it is useless. Asafoetidae for instance produces nothing but a little [illegible] in healthy persons 77:e. preparations & other deobstruents will be valuable adjuvants. The metallic tonics as the preparations of iron & of zinc, the mineral acids, myrrh, bark, the various bitters & the astringents have been found useful I have used alum whey with advantage. Among us the geraniums & all the indigenous aromatics & bitters have been given in popular practice. Alcohol from its stimulating effect upon the digestive organs will be a useful vehicle, for the exhibition of medicines. Condiments used freely with the food, will answer to the same indication The diet of patient troubled with worms should be dry & stimulating, rather than liquid & cold raw fruit, acids cold water & all indigestible articles should be avoided & in extreme cases I would advise that neither food nor drink be taken but which has not been subjected to heat. I have apparently cured patients by this means. “[illegible] toasted bread [illegible] [illegible] vegetable [illegible] though they occasion [illegible] dyspepsia” A multitude of heterogeneous articles have been used as anthelmentics, besides those already mentioned; some of them are sugar; worm-wood; rue; peach flowers; bark’ of prunus virg; valeriana selequa used by the French; muriate of barytes; injections of mur. of tin (Alibert); oxide of tin grs iii with etr. of juniper (Alibert) mur. of amm. of linseed; mur. of amm. [illegible]I with jal. or rhub 10 gr.; all the forms of ammonia; crude mercury; merc. boiled in water; aethiops mineral; artemisia [illegible] [illegible] ([illegible] [illegible]) & a. [illegible] [illegible] [s?tonica] worm seed bitter & of some value; melia azedarach much used at the south; butternut bark intensely bitter dose a tablesp. full of decoct cathartic & said to be narcotic; allows asclepiadis I think I have seen the a. [illegible] then beneficial; etc. etc. Garlics seem to do well how it is difficult to say perhaps operate upon the worms. Garlic also will relieve the eruptions of worms. It is though also that garlic prevents worms I have a very good opinion of sulph ether introduced into the rectum used by the Germans, Italians nervine & antirritant. It is valuable both in cases for worms & in those of irritation & affections of liver severe pain in bowels etc.” ½ oz or 1 oz. iron filings taste by [illegible] remedy worse than disease Wherever leaves of [illegible] are recommended you may give our common juniper For the imported [illegible] loses its strength by keeping & drying Rosenstein recommends cold water during the operation of a cathartic He recommends effervescing mixtures to destroy the worms by carb. acid An old remedy of the tonic kind is alum whey Rx milk & water equal quantities & put in [illegible] [alum] to [illegible] give the whey [illegible] children takes it pretty freely; It is a given in cases of relaxation of bowels and for ascarides & round worm It is of consequence often to have a remedy [illegible] and not require to be forced down 77:f. Various external applications have been prescribed Oxgall & venice soap aa zi made into a liniment with oil of tansy or wormwood; Aloetic plaisters; ether oz vi, bruised garlic zi, camphor zi (used by the German Brera) for a liniment; petroleum mixed with gall; Most of the patent medicines for worms [illegible] or both contain calomel, Storr’s lozenges are calomel with sugar & gum. These are his white lozenges. His brown are resin of jalap, gum tragacanth & calomel. Good on the authority of the Germans recommends [illegible] milk Electricity A popular article (cath.?) is decoction of [plantanus] occidentalis strong bitter For ascarides I rely as much as any thing upon a saturated tincture of the juglans [illegible] & [illegible] All the indigenous bitters as cherry bark [illegible] melia [azedarach] zii of recent root is divided doses ½ pt water. When dried & long kept it is apt to disappoint here. It is acrid [as the] narcotic & cathartic a powerful article The berries are also narcotic causing lard to fall down not from [choking] as has been thought The [planters] think it too powerful for [white] children! Tape worms frequently produce headache [illegible] about the umbilicus yet generally produce a sense of weight. Yet I have known persons evacuate them when they had not been suspected Case of a man who had kept taking remedies for a catarrh Finally a medicine ? brought away to his own surprise and that of his physician a tapeworm Perhaps vomiting occurs oftener from tape worm than from any other species # “When the worms are very numerous, there is a sensation of something falling from side to side on a change of posture” 78 V. Symptoms of each of the kinds of worms with the treatment. 1st taenia solum. This worm generally inhabits the upper part of the intestines & adheres so firmly as to be removed with difficulty It is sometimes solitary but commonly in considerable numbers. When brought away from the bowels many of the joints are separate & have the appearance of gourd seeds hence the name. 2 T. lata or vulgaris This likewise inhabits the upper part of the intestines and is usually in families of three or four Both are called by the common name of tapeworm They may exist without any apparent symptoms of worms or they may give rise to the severest affections In general they are attended by severer pain in the bowels & more violent symptoms in general than the other worms. The diagnostic marks of their presence in great quantities, are sense of weight in the abdomen, # irritation of the stomach nausea & vomiting loss of appetite, irregular appetite weakness of the chylopoietic viscera, bloated countenance emaciation of the body etc. All these symptoms however may arise from mere irritation of the stomach of a child Adults are more generally affected with tape worms but children sometimes have them. For the taeina solum t. lata or vulgaris or cucurbitina the gourd seed worm the spirits of turpentine has been very successful. Though not prescribed by the physicians it has been used as a popular remedy here for more than T. lata fifty years. I have known a man of intemperate habits No cautions are given about the use of the article (so far as I know) But if it does not act as a cathartic immediately, it will produce great irritation especially of the urinary organs I recollect the case of a lady who had been treated with aph turp. in N.Y. taking 2 or 3 ounces Violent vomiting & catharsis had been produced and the tone of the stomach and bowels seemed to have been permanently destroyed Worry had indeed been brough away, but then they would come away themselves & the relieve was fallacious In delicate cases it had better be combined with castor or sweet oil In the case of the lady cath seemed to do no good, they would indeed bring away large quantities but they would return in a few days. I put her upon arsenic but she left town and I have not heard from her It is difficult to tell how arsenic operates whether upon the worms or producing healthy bile For the t. lata the spts turp. seems to do better 79 take a wine glass full of spirits of turpentine to expell a tape worm Though an habitual inebriate, he said he never had been so drunk in his life & large tape worm of this kind? came away # It is said sometimes to intoxicate & sometimes to produce irritation T. solum 2d The t. lata is the most difficult of all worms to manage. Spts of turpentine do no good at least in those cases in which I have tried the article In T. solum one case I gave zfs. In another I gave it in teaspoonful doses. In the latter it operates freely as a cathartic a single teaspoonful procuring as many as ten stools Worms were evacuated but they would make their appearance again in as large quantities as before. Indeed any medicine may bring them away for the bowels are sometimes so filled with them that they come away T. solum when the patient is walking, or is asleep. I have known two quarts to be brought away in a day, & then a fresh supply in a few days after! T. solum # Arsenic has succeeded better for this kind? with me than any other remedy, which I have used. In the case of a child 5 or 6 years of age who had both the round & the gourd seed worm the common cathartics were given with some advantage, as some worms were brought away; but the symptoms still continued and the worms passed occasionally with the stools. Fowler’s solution of arsenic was administered in doses of four drops three times a day. In a few days worms ceased to be evacuated the symptoms disappeared & the child has once had no recurrence of the worms [Osmunda] cinnamonea is bitter, subastringent and perhaps deobstruent. So is polypodium vulgare and perhaps more decidedly so The polypodium vulgare & felix mas They are used in chronic affections of the stomach & bowels & thought they have not obtained much reputation for worry in this country yet they have sustained their reputation for 2000 years. It was used by Galen “The [form] is tonic” 80 I recollect case of one patient, a woman, who kept passing tapeworms, in great quantities, for months. After failing with medicines I threw them all aside & tried diet All the food taken was roasted or boiled even the water used for drink was boiled. She was cured. It must be remembered the healthy bile & gastric fluid will destroy those worms & from this fact results an important indication, which I shall presently dwell upon. Felix mas the male form has been considered in Europe, as a specific for this worm. With us the osmunda cinnamonea [illegible] ([hog brake]) has been used as a substitute for it. It is bitter, astringent & sweet. The polypodium vulgare, which is tonic & deobstruent, & other forms may probably be used also The famous fern remedy bought by the king of France of Madame [Nouffleur] is as follows. Take a super of the following panada Rx water lbi [illegible] fresh butter z 2 or 3 bread cut into small pieces zii add salt zi & boil thoroughly. If the patient is costive give an injection of water lb is in the evening olive oil zii salt gr. s. The next morning eight or nine hours after the supper the specific is to be given viz. Felix mas ziii in powder, mixed with 4 to 6 z of the distilled water of the fern or the flowers of the linden tree the whole to be swallowed at a dose. In children the dose is reduced to zi of the fern Two hours after the fern is taken the patient is to swallow the following bolus R. cal. & scamm. aa grs xii Gamboge grs V powdered fine & made into a bolus to be given at one dose to a person of vigorous constitutiokn Ether acts especially upon the nervous system on which account it has been used as an anthelmintic Alibert for taenia gives about zi in a glass of the decoction of the male form in the [illegible] an hour after his doze zi of the ol. ricini are to be given in syrup or in composition the dose to be repeated twice & sometime three times a day The worm is usually evacuated after the first doses Mr [Bonadier] directs an injection of the decoction of the male form to which zii of ether are to be added Mat. Med. art. ether 81 Mathieu adds to Mad. Nouffleur’s remedy the filings of tine & the sulphate of potash The French & German add ether to the same remedy Rothier’s method is Rx powdered savin grs xx seeds of rue 15 cab. grs x oil of tansy gtts xii syrup of peach gr. s. make a bolus Take half in the morning & half after dinner, drinking with each dose a glass of vin. tincture of peach kernels Dr Baurdier gives the following Rx sulph. ether zi decoct felix mas 1 gill taken fasting 4 or 5 an injection of the same decoction with zfs of ether an hour after zii ol ricini or zi of the syrup of peach blossom the worm is discharged half organiz Oil is used in order to kill the tape worms by filling their respiratory foramina. Ol ricini has been given for taenia & other worms in doses of 3 or 4 z Liquid carb. amm. might be given for taenia The German physicians are fond of giving 3 or 4 ounces of castor oil They are fond likewise of peach flowers Within 5 or 6 years the bark of pomegranate has been recommended. Paris says bark of the root [illegible] probable however the office preparation is meant viz rind of the fruit which is the most astringent substance to the [illegible] which we have [illegible] also cathartic! I have not [illegible] N.B. The male form is astringent, and is given to enable the bowels by the tone it gives, to bear the [strong] cathartic afterwards. Hence the union of these give in [illegible] [illegible] may be useful I have seen the worm occasionally in rain water I recollection one man of 60 who informed me he had been troubled with then nearly all his life until he removed his [illegible] Change of place may effect a cure by change of water Probably [illegible] of our cholera are troubled with this worm delicate children only suffering much children troubled with them will be faint, have turns of colic etc. you will be called [illegible] Give an injection, and no worms will come [illegible] yet give afterwards a strong cath. & or repeat the injection and worms will come away proof that they were not in the rectum They probably breed in the duodenum I have known but one case in which they were vomited up. The subsequent cath. will bring away smaller worms More is done by diet int his worm than by any thing else Alcohol in this morning especially its bitter tinctures. Condiments are useful. Worms are less common now because condiments are more used. It is said that the aborigines when they cannot get salt used potash ashes by a condiment The aborigines are said to be very subject to worms # Ascarides sometimes produce severe pain at the umbilicus and colic # “Ascarides though often found in the rectum are generated in the stomach & small intestines. Hence they are sometimes no discharged till the second or third operation Hence they are sometimes thrown up by vomiting. I have examined this point carefully 82 3d Ascaris vermicularis. This worm is always troublesome when it exists in considerable numbers though it is but seldom that they exist in healthy persons in such numbers as to give rise to morbid symptoms. They are very common in children, and not rare in adults & are called by the generic name ascarides These worms are commonly found in the rectum & hence are often said to inhabit that part This is a mistake they multiply abundantly & lodge in the rectum as they daily pass void by sphincter. Sometimes they exist in the stomach in vast numbers (hence called maw worms) so as ever to threaten suffocation by rising in a ball into the esophagus & sometimes they cause severe griping pains by their presence in the small intestines # They pass in the stools & sometimes come away spontaneously at night, they are said even to make their way to the vagina & urethra of females producing troublesome symptoms X Ascarides are most troublesome in the latter part of the day & the first of the night, when they excite an intolerable itching at night [illegible] probably than feeding They give rise to symptoms of general irritation & sometimes to a cough # Ascarides are particularly injurious to dyspeptic patients & they themselves may give rise to the symptoms of severe dyspepsia such as craving appetite, indigestion, faintings. Flatulence, cold extremities pale & sallow countenance, cough etc. The irri “They are attended with violent itching about the rectum general irritation convulsions irregular appetite pale urine flatulence want of vigorous action of chylopoietic viscera increase of mucous secretion darting pains in the abdomen stomach & chest faintness cold extremities the symptoms of dyspepsia sporadic cough” Tobacco injections & tobacco smoke injected are very useful and will often cure. It is not safe for children I have seen great prostration produced in children & I have known an adult killed by a tobacco injection # A physician who had been much troubled with ascarides told me he had tried merc. oint. externally with advantage. “I have used it but was rather disappointed # When the ascarides are in the small intestines, tobacco smoke will do not good & by its debilitating effect will favour their existence “Injections of camphor and milk have done more to remove ascarides than all other remedies I have used. The injection immediately removes the irritation produced by the ascarides & the ascarides themselves. It may be made of milk ziv to spts camph. zi This is the form in which I have used it, probably an emulsion is as good, perhaps a better form” M. M. 83 which they cause sometimes, in children brings on convulsions Whenever, finally, they exist, in the alimentary canal they are accompanied with great quantities of mucus in this part. They feed on the mucus of the intestines, the flow of which they excite by punctuating the mucus membrane Treatment It is very difficult to cure a patient troubled with ascarides. The most immediate relief is given by injection. If the worms are in great quantities & too much “Tobacco smoke is one of the most powerful means we possess for the involved in mucus, they may be completely removed by cure of these troublesome worms” injecting tobacco smoke. Injections of warm water or milk & water will relieve for the time being by washing out the rectum & if a quantity of aloes zis to ½ pt is added a still better effect may be expected though camphor being a nervine & a poison to the worms would be a still better addition. Injections of milk and water, with camphor zii tinct camph to ½ pint, will if preserved [illegible] destroy them 15 grs of [illegible] [saladilla] have been injected. Still the frequent injection, required in bad cases may debilitate the bowels & consequently invite the return of the worms. For internal administration. I have found a tincture of the buds or bark of the hickory given in doses from a tea to a tablespoonful one of the best articles both for removing the worms & for preventing their return Drastic cathartics should not be depended upon for they weaken the bowels & increase their irritability & hence favour the production of the worms. On the contrary calomel & tonics should be given to restore healthy secretion Aloes if given should not be in large doses, for that will irritate the rectum still further, but in smaller ones as a tonic Oily articles shd be avoided as butter, because they relax the [illegible] of the intestines Potatoes, vegetables All kinds of pastry avoided All the metallic tonics are useful as tonics They are thought also to be unfriendly to the worms It is said that forth ascarides a pint or a quart of sea water has been drunk with advantage, producing vomiting & purging. Salt is a good remedy. Dr Rush proscribed a teaspoonful of salt in the morning to a gentler one much troubled with ascarides. He told him after trial than the remedy would not do. Dr Rush gave him, then, for worm powders # For the worm the [illegible] the pink shd be the remedy vide [illegible] “Rhub & cal. are the best cath. but all are useful For children Rx tinct. [illegible] Fowlers solut. cold water” “Common salt ground up with cochineal to colour & disguise the article. The gentleman reported that the last prescription had answered well. Dr Rush also believed in sugar. This more doubtful The asclepiasis have been much used especially for this worm especially A. incarnata called wild hemp It is dried pounded to a fine powder mixed with molasses & given in doses of a teaspoonful Or [illegible] down and make a strong decoction [illegible] the [illegible] with it molasses and give freely until it moves the bowels This much used by the practitioners of the state more than any other article after calomel. it is an article which may always be obtained growing in clayey situation and is safe The other asclepians are similar & may be used S syriaca is the most laxative 84 To prevent the return of ascarides, condiments should be freely used such as pepper, ginger etc. in short all warming and bitter things In extreme cases let the diet be so regulated that nothing shall be received into the stomach which as not been subjected to heat. Mercurial ointment has fasted in my hands. 4. Ascaris lumbricoides the long round worm is perhaps more commonly found in the alimentary canal than any other This worm more than any other is found to have existed in the stomach or intestines while the general health has been good is the presence of worms not suspected. Strong purges may be used to remove them & alcoholic tonic tinctures given to prevent their increasing. For this latter object the carbonic acid has been recommended in the London Med. & Phys. Journ. & in confirmation of the idea I have used soda water with advantage Melia azedorach or pride of India a decoction of the bark is much depended on at the south for their young negroes who are much subject to worms. It loses much of its virtue when dried. The spigelia is also sued but of this I shall speak under the head of general treatment. I recollect with an aff. of the liver wh often vomited up dark [gravous] blood, which had evidently been long in collecting. Finally he was said to have thrown at a snake. Many eyewitness testified to the snake & to its eyes & teeth. I saw it. It was a very large round worm of the kind To be distinguished only by the violence of the symptoms. The same itching at the arms will exist as of the ascarides, but non violent etc. “Treatment similar to that for ascarides. It is more common than is generally supposed. Many of disease & death by irritation from an unknown cause, are probably owing to this worm. In examination the contents of the bowels should be placed upon linen cloth and then this worm can be seen.” For the gordius Linnaeus recommended the angelica Archangelica (not our viz the [atropur????]) 85 5. The tricocephalus is but seldom met with The irritation produced it may be so great as even to bring on delirium & will be manifested by screaming throwing of the hands & [fat] etc. I have found this worm in a fold of the volvulus of the intestines vide Volvulus. I should try narcotics for this worm, but cannot speak from my own experience. I should recommend also an injection of a table spoonful of ether in a gill of water or mucilage. Ether given in this way will undoubtedly pass the valves of the intestines in a state of vapour Vesicular worms, according to the old division of verminous diseases, are met with commonly in the brains of adults & are attended with the symptoms of vertigo, convulsions apoplexy & hydrocephalus. Cases of worms & of colic are much less frequent with us than formerly; owing to the change in our mode o f living. They are said to be very common among the aborigines of this country One volvulus may be received within another a second, a third and fourth time & [illegible]. The whole may then become inflamed, the vessels may run from one to another, and the whole become one complete mass of organised matter or sometimes [illegible] “It may occur in any part of the intestines except the rectum though the colon is often received into the rectum” The symptoms of the two kinds [illegible] [illegible] owing to the different susceptibility of these two portions of the al. canal, and the diff. ages of the subjects of each Nor located in books vide Ed. med. & surg. J where the best account of it is given. Good merely mentions it as an accident that is found sometimes to have occurred in ileac passion “Predisposing of exciting causes” The cavity of the natural stricture may not be large than a goose quill, & such children will be very liable to an occurrence of volvulus This is not a primary disease. It occurs more in some families of [illegible] fibre & [illegible] phlegmatic temperament It may occur from debility of constitutional or that of the bowels [illegible] by bowel complaints etc. Local violence One instance, in here the child was apparently thrown into it by being carried over the shoulders 86 Volvulus or Introsusception This is a disease with which I was at first very much perplexed especially as I derived little satisfaction from the books Volvulus or introsusception is the reception of one portion of intestine within another. It doubtless exists often in a slight degree, when there is a strong action of the bowels & are inverted peristaltic motion & the bowels disengage themselves. Sometimes there is a double involution, or one involution within another. In some cases likewise the cavity of that portion of the intestine is entirely obliterated by the tumefaction of the coats. I have always found in post mortem examinations, that the upper portion of intestine was received into the lower & not vice versa the involution having been caused apparently by inverted peristaltic action This affection of the intestines occurs oftenest in children though adults are liable to it. It would seem also that some families of a leucophlegmatic temperament & delicate constitution are particularly liable. It may be caused by a natural stricture of a portion of the intestinal tube when it will be incurable It may arise from extreme irritability; local violence & injury may occasion it, & the irritation of worms may bring it on. Drastic cathartics may bring on volvulus & hence should be cautiously avoided where there is a liability to it. Bowel complaints, as colic, cholera, dysentery etc. sometimes terminate in one or more volvuli of the small intestines. The disease is more frequent in the summer, when debility is greater & bowel complaints prevail “Symptoms incessant irritation one or two copious evacuations but usually these have ceased entirely before the physician arrives constant efforts to vomit, resembling hicup constant efforts to pass stools & nothing passes but mucus streaked with blood Generally mistaken for hydrocephalus In bowels complaint of delicate children look out for volvulus It is much more common in some seasons than in others. About 10 years ago they were quite common. I had many letters from our students, who met with the disease & disagreed with the phys & gained [reputation]. They frequently sent me such accounts. Sometimes there will be a partial involution of the large intestines [illegible] to relaxation of inner membrane what descends like a funnel & may be felt by the finger # In the large intestines there is not very much irritation than is torpor of al. can. not much vomiting except upon the administration. There is no purging You may sometimes determine that of the large intestine by heaving the peristaltic action discard & stop at the [illegible] This is most common in adults. The symptoms are more mile # It occurs in females who have had long continued effetion of uterus, occurring in females about cessation of [catamen] and from long continued bowel complaints. The [inner] membrane will descend like a funnel An injection will perhaps 87 Symptoms These will be different according as the affection is of the small or of the large intestines 1st Where the small intestines have one or more volvuli the symptoms [illegible] vomiting or Symptoms like those of violent injury to abdomen vide case 1st 6.89 a constant endeavour to vomit as often as once in ten or fifteen minutes the matter thrown up being a greenish fluid or simply mucus. In severe cases the vomiting is attended with a discharge from the rectum at the same time. The stools are fecal at first & copious but afterward they are small in quantity & consist principally of white mucus streaked with blood the blood not being diffused throughout the mucus as “no fecal smell generally” in dysentery, but in streaks or specks. These symptoms are attended by others which indicate great inquietude or irritation such as throwing the h ands & feet, rolling the head paleness of coutenance This set of symptoms resemble those of hydrocephalus & hence volvulus is often mistaken for this disease. The pulse is small and frequent “[illegible] usually occurs in 24 or 36 hours” 2 A volvulus of the colon or rectum is not usually attended with much vomiting unless this is excited by cathartics. It is attended with the ordinary symptom of constipation. There is no evacuation from the bowels unless at times a little blood and mucus. If the passage be not completely closed, an enema thrown-up will remain & not come away if completely closed. it either cannot be thrown up or it returns immediately. Blood often follows the introduction of the pipe. Indeed the inflamed part is often so low as to be reached by the pipe & admit of being felt by the finger. come away immediately. [Schyl?la] of feces may come away And large quantities of mucus may come away sometimes ½ a pint. This is not apt to be fatal. Treat by a strong inject prescribe for the [illegible] with conium [illegible] etc. mechanical means The more cath. you give the more the unsolution is increased therefore give more Give mucilaginous injection, in involution of the small intestines, sufficient to fill the intestines. If it is said that the injection will not pass the valves. I answer that whether by sympathy or in whatever manner, I am satisfied of its utility # Give [illegible] enough to allay irritation I have treated # patients for 8 or 10 days without evacuation & cured them Not long since I had a case in what I suppose there was such a volvulus, for the attendants could not make the child receive injection. “thought the bowels were swelled” The child was suffered to get 8 or 10 days without evacuation & eventually died of another disease with which this was connected # In the incipient stages, filling the intestines with warm water [illegible] recovered. I was led to it from its [illegible] strang. hernia I am satisfied it acts well as a local nervine etc. I would recommend the injection of ether in cold water table sp. to a gill warm wat. will make it fly off. The inject of it is practised by the French & Germans. Other antispas. might be [injec??] is asaf. petroleum etc. 88 We may often hear a rumbling noise proceed as far as the stricture & then stop. Treatment The indications of cure are principally, to relieve the excessive irritation both constitutional & local & to attempt the restoration of the involved intestine chiefly by mechanical means When the small intestines are affected we must give opium and aromatics & depend mainly upon these as internal remedies, until the intestine restores itself. As an adjuvant the warm-bath will be valuable & fomentations or irritants, as mustard & horse radish leaves may be applied to the abdomen. Soothing injections also may be copiously given. The quantity of opium which will be safe at a dose may vary from half a drop to 30 None but the mildest cathartics are safe, as blue pill and aromatic tincture of rhubarb I have succeeded in giving only a decoction of senna & the blue pill [Savage] When volvulus is in the large intestines all our remedies must be given by injection. The warm bath etc. may be used & we may also attempt the restoration mechanically, by means of copious injection repeatedly given & thrown up with force Two cases are related of young men cured by inserting into the rectum & keeping these for a considerable time as spermacete candle with a quantity of opium at its extremity. The first case which I had I treated for constipation with repeated cathartics, which are thrown up etc. The attendants complained that they could not give the injections when I ordered I was ignorant of this case Tried warm bath & every remedy for colic constipation etc. Upon examination at first the colon was apparently wasting at the sigmoid flexure where there was a large tumour which we thought to be a malformation It proved to be a repeated & insolution of the intestines Inflammation had taken place & the whole was adherent, some [illegible] Afterwards I was called too late, to a similar case which upon an examination showed circular appearance Afterwards called in consultation to a child said to have hydrocephalus all the children of which family had died in a strange way. I pronounced the disease not hydroc. but some could not say what was the matter. No treatment was serviceable. Examin showed volv. of small intest. Symptom is above. vide p. 204 The children of the family were subject to diarrhoea & were leucophlegmatic. I afterwards [illegible] the family and was very cautious about cath. giving nothing stronger than blue pill or tinct. rhub. The family raised 5 or 6 children afterwards Case of a student [unaccountable] Dr Munson & Dr Smith at a loss. [Cath.] retained & yet not thrown off by vomiting Sitting by him I observed a rumbling noise Which he said upon my enquiry, he felt & which stopped. I felt the stricture. Spermacite candle, sharpened, opium at [end]. kept up about a [illegible] [renewed] afterwards injection passed up Case of a gentleman on the wharf similar cured 89 Cases. A man over whom a cart had passed without leaving any external injury, died with all the symptoms of volvulus of the small intestines. On dissection the duodenum was found cut entirely in two. One remarkable physiological fact occurred in this case; a cathartic was given by the mouth & produced a regular evacuation from the anus, although the intestine was completely severed. An interesting case occurred to me in which the worm ascaris tricocephalus was found to be the cause The worm lay in this fold of the intestine. Grace Linsey, a delict schoolgirl on was taken with slight in disposition for 3 or 4 days the rejected her food by vomiting then came on constipation with vomiting attended with great restlessness & throwing off the bed clothes, cold extremities, low & small pulse the tongue not much furred, little or no thirst, no tumefaction of the abdomen no determination to the head. She was visited on Tuesday and died on Saturday. A blue pill was given & followed by 15 or 20 grs. of calomel in divided doses No effect was produced though they were not rejected. Opium and stimulant were tried but were not retained. There is no pain but faintness & an uneasiness about the alvine & urinary passages. Both copious and small injection pass up well but produce no evacuation. On Wednesday injections produce stools which are clay coloured. Black vomit came on two days before death. P.m ex. liver very pale little bile in the gall bladder no marks of inflammation cavity containing the intestines very dry as in cholera. Two volvuli were found one in the ileum which was disengaged with difficulty, & one in the jejunum In other cases with similar symptoms I have had supposed there was volv. caused by worms, but have had no opportunity to examine Vide p. 204 [illegible] Lindsay’s case continued. After the examination we accidentally observed some of these worms minute & coiled up among the mucus on the cloths. The worms seem more calculated to irritate the bowel than any other “If it could have been known that the worm was there, perhaps tobacco should aught have succeeded # It is called leg ache in slight affections alluded to by DR Rush Affects the legs, calves of the legs [illegible] continues extends up to the [illegible] coats” It is a disease manageable in its commencement Being a severe disease it calls for decisive remedies The indications are to allay pain equalize excitement & promote peristaltic action by opium by diaphoretics by cath. Cal. in full doses some would call 5 grs a full dose some 10 But if 5 gr. should be given every hour it would amount to a full dose. You may give 10 gr. 2 or 3 times repeated. AT the same time apply warm bath & fomentations not regarding your giving cath. Put drafts at the feet. Follow the cal. with senna, salts etc. But do not be too anxious about the calomel’s operating immediately It is better that it shd lie sometimes in [illegible] vessels With the cal give opium also guiacum & guaicum with dovers powder the latter to act on the skin and the whole to produce a decided [nerve] action affect on the al. can. and on the whole system 89:a. Nervous Rheumatism Infantile neuralgia This is a disease which has never to my knowledge been described in the books, though it may have existed unnoticed I first met with it some years ago, but it is [not] some years since I have seen of a case. It may occur again It occurs in the winter and spring mouths & occurs after exposure to cold especially after the feet have been in snow water. Children are the only persons that I have known attacked # This disease is in its symptoms allied to neuralgia acuta. The affection leg ache is probably allied The attack is sudden after exposure to cold with excruciating pain in the inferior extremities sometimes rigidity of the whole muscular system more or less disorder of the digestive passages (apparently the muscular coat of the intestines is affected) abdomen frequently tense and full stomach sometimes irritable. If the disease advances there is nausea, vomiting, tumefaction of abdomen (appearance of tetanus?_ (coma?) etc. and the patient dies in 4 or 5 days The indications of treatment are to equalize excitement by acting upon the whole surface of the alimentary canal and skin at the same time introduce new action in the system commence with a full dose of calomel 5 to 10 grs or 20 & follow it by senna and manna, or castor oil and enemata “I do not expect that cal. [illegible] I as above will operate at 8 years therefore follow it. Immediately after administering the calomel I put the patient into the warm bath or the feet in to the tepid bath, wrapping them afterwards in flannel or boil cedar boughs in water, roll them in cloths and apply them to the body & feet. Irritants also may be applied to the extremities and to the abdomen Sometimes it will be best to repeat the cal in the course of 2 hours. The stools will be fetid and dark but this must not be considered as an indication for further evacuations as the appearance may be caused by the calomel, and is a sign that secretion is beginning to take place. After producing free evacuations by your cathartic you must keep up a regular course of exciting the secretion by cal. & guaicum with Dover’s powders, especially if pain continues & keep up a diaphoretic action by Dover’s powders calomel and camphor alternately increasing doses if necessary. Calomel and gum arabic, as an emulcent, & calomel and decoction of cedar twigs, as a diaphoretic may be given Give the calomel first in divided doses If cold applications are made to the extremities, to discuss the inflammation the disease is translated to the stomach and death is the consequence I called in the first stages, & am always successful in effecting a speedy cure The irritation of the system is so great that secretion is prevented hence the production of secretion I have been called to patients with [illegible] where little had been done the abdomen was swollen the patient went into a comatose state & died and that too where the disease was not of the most violent form After the bowels are thoroughly evacuated depend upon diaphoretics camphor guaiacum and [illegible] etc. giving so as not to offend the stomach and beginning gradually It is a violent and excessively painful disease and it is a great satisfaction to the phys. to cure it Dark stools [illegible], satisfied “The pain usually begins in the calf of the leg and extends to the contiguous parts. Sometimes it is attended with tetanic spasms & a constant rigidity of the abdominal muscles. The stomach becomes in these cases irritable, and nausea & vomiting prevail. In the progress of the disease the abdomen becomes full and tense, with constipation.” “It should be our leading object to make the muc. men. of al. can. & the cutaneous system active [concert] After the operation of cathartics, if the pain is severe give diaphoretics with opium, as Dover’s powders. Camphor & cal. in small doses as an alterative. If the stools are watery & fetid give opium ¼ gr. guaiacum 1 or 2 grs. camph. 1 gr. Ipecac ½ gr. with cal. repeated till some effect is produced not to salivate, but to this children are not so liable as adults” Young physicians are often called in a case of convulsions as their first case The neighbors & friends (women) have assembled in great numbers and their sympathies are excited. Hence an impression is made with respect to a young physician’s talents which will be of great service or detriment Morbid condition to brain so that ordinary stimuli produce convulsive action Convulsion fits may continue 5 m or from 1 to 2 hrs 90 Convulsions vide costiveness 12:a This is a very common disease of infants. The mortality from it is truly appalling nearly one seventh part of the whole number or deaths of patients under the age of puberty by the bills of mort. in Phil in 20 years Medical writers commonly make two kinds of convulsions idiopathic and symptomatic, the former arising from some morbid condition of the brain and nerves and the latter from some other disease, or from irritation. Children are subject to both kinds & most of the diseases of children may be expected when they prove mortal to terminate in convulsions The causes of symptomatic convulsions are as various as the agent capable of producing irritation though the causes of convulsions in one child will not necessarily produce them in another. The susceptibility to them varies with the age of the child and the peculiarity and degree of delicacy of the constitution. Convulsions may arise from the sudden suppression of evacuations to which the system has become habituated. Irritation from teething is a very common cause. Worms in the alimentary canal may excite convulsions. But perhaps the most frequent cause is the presence of indigestible substances in the primae viae. irritating the nerves of the stomach & through them those of the whole system. Over distention of the stomach, even with food of a healthy quality interrupt the progress of digestion & the food undergoing action [illegible] fermentation “Or the excessive quantity of food may produce convulsions from the mere stimulus of distention” “Dyspepsia is a cause” This is an important maxim in the first children of young mothers Their anxiety of mind will often affect their milk 91 in the stomach, becomes noxious matter & excites convulsions In the season of fruit we may always suspect this as a cause in children old enough to eat it. Calomel has been known to be so irritating to the system as to bring on convulsions Costiveness also is a cause of convulsions in children A change in the quality of the milk of the mother or nurse, produced by improper food or by strong affections of the mind, in some instances is the cause of convulsions in young children. Hence not only the diet of nurses should be regulated, but their minds kept tranquil. It may be observed also that the countenance of the mother or nurse as also those of the bystanders has more influence upon children than is commonly supposed. Even a child but 3 weeks old, will be strongly affected. In some families there is said to be an hereditary predisposition to convulsion among the children. For the treatment we have two indications 1st to remove the exciting cause where this is local & 2nd to relieve the irritation of the system 1st We must enquire into the causes with with care. If evacuations are found to have suddenly ceased they must be restored. The guns should be lanced. Anthelmintics should be given if there are worms If improper food is suspected we must be particular in our enquiries, or we may be misled by a [vague] & general answer. When the convulsions have been brought on by improper food or by food in large quantities recently taken the stomach should be evacuated by an emetic of 5 or 6 grs 4 to 8 of sulph of zinc or of ipecac. # How long should we wait after giving one cathartic before we try another? the child being in convulsions all the while? The equilization of temperature will do a great deal to remove convulsive action Besides the soothing of the [nerves] etrc. Some rely on one and [illegible] or another Oil of a amber is not in my opinion better than many others The oil of amber apparently is the [illegible] the oil of [capal] brought from its E. [illegible] It is recommended to dissolve the oxyg oil in [illegible] [but] it is slow of solution It dissolves readily in either 92 If the offending substances have probably passed the stomach & the irritation is in the bowels, these must be evacuated as speedily as possible giving and injection to begin with [illegible] it to [illegible] cathartic. Sometime it will perhaps be best to give a dose of calomel large enough as to operate both as an emetic & cathartic. Frequently large & repeated doses of cathartics will be needed in order to overcome the torpor produced by an excessive quantity of food. The food also diminishes the cathartic operation is the case with the French [dinner] pill. We may give calomel, 5 to 10 grs. or scammony 3 to 4 gr. jalap 2 to 3 gr. senna & manna, castor oil, neutral salts etc. If dry cathartics fail to produce the desired effect, the liquid should be tried. Sometimes will be acted on by one kind when they will not by the other # If one fails after 3 doses try another & assist with injections Begin with cal. & follow with the others 2. If the convulsions continue after the removal of the cause we must rely upon antispasmodics or even at the commencement. Of these the warm bath must be considered the most powerful remedy in convulsions of children always [illegible] & often efficacious. Its influence is immediate and extensive. Antispasmodics, as pearl ashes or aromatic herbs, may be put in to the water of the bath Of antispasmodic articles a great variety are used. Oil of amber Dr Rush called his sheet anchor in spasmodic diseases. It is useful internally, and applied as an external irritant along the spine. The artificial musk a preparation of amber is in my opinion a better article than amber itself, for all cases where amber is “# Seneca oil is more limpid & pure & approaches nearer to naphtha” Soot is a [illegible] Soot is efficient as a nervine tonic & deobstruent It is sometimes very efficacious in jaundice & dyspepsia It was very popular in Philadelphia with ashes for stomach complaints “The British oil is manufactured in this country from Barbadoes ter & spts turpentine” The nostrils may be rubbed & it may be given internally “also rubbed on the skin” Though so offensive to the small yet children taking the tinct readily potash [illegible] & [illegible] All the alkalies & alkaline earths are antispasmodic. They are not nervine properly. There yet seems to be abundant testimony to their antispasmodic properties. They are to a certain degree tonics. i.e. they have a specific action on the mucus membranes. I have maintained [illegible] they operated by generating excitability a view supported by Jobe vide Hufeland’s Journal in Lond. Med. & Phys. 93 indicated. The mineral oils from whatever source obtained, such as petroleum, seneca oil, British oil, are little inferior to the oil of amber I prefer the seneca oil 5 to 30 drops #. The eympreumatic oils are useful antispasmodic and soot is often given by nurses in decoction Ammoniae in any form is a good antispasmodic A solution of ammonia in spirits often contains an empyreumatic oil of this solution we may give to a child from 2 to 6 drops in an ounce of water. Either the spirt, the carbonate or the aqua ammoniae will be useful in alleviating spasms in children either applied to the nostrils, rubbed upon the skin or given internally. Dippel’s animal oil, a very fetid substance distilled from bones in a state of putrefaction owes to antispasmodic virtue to the presence of ammonia. It is too disgusting Castor and valerian are good articles of this class, but in cases of children they are too bulky & a sufficient quantity cannot be introduced into the stomach. A more powerful article than these is the asafoetida fetid gum 10 or 20 40 drops of the tincture. This is a very valuable remedy to give by injection using for this purpose either the tincture zii or a decoction all the alkalies are antispasmodic & are proper for children. The most powerful is pearlash given by injection, zi to zii in lbis of water I have seen more sudden and permanent effects in cases of spasm produced by injection of this kind, than by any other remedy. It has been successful in cases both of In for [illegible] who have [resumed] in convulsion 2 or 3 days when a variety of narcotics had been given. I have seen surprising effects produced by the injection These applications sometimes fail & we cannot tell to what sort of cases they are Yet we must have a variety of resources if we would be able practitioners Opium is powerful, but though it frequently relieves, yet it sometimes aggravates the symptoms I have given it with great success in paroxysmal convulsions anticipating the paroxysms yet in these it will sometimes fail 94 infants and of adults. Sometimes however this remedy fails & I am not able to point out in what particular “We are compelled sometime to practice [illegible]” instances it is indicated. All the narcotics are antispasmodic. Opium is a powerful antispasmodic and may be given to patients of any age when the condition of the system does not contraindicate it vid. lect on m. m I have given opium where the convulsions were violent & returned at stated periods with fever preceding. When the convulsions appear at regular intervals, as once in an hour, or day, opium in repeated doses may be considered a specific. Counter irritation may be valuable adjuvant in the treatment of convulsions. Oil of [origanum] & similar articles may be rubbed along the spine drafts may be applied to the feet and wrists & mustard horse radish leaves etc. to the abdomen. When the convulsions are frequently repeated in children and become in any degree periodical, a cathartic of calomel given once or twice a week, rarely fails to prevent their recurrence. If this fails I give stramonium or other narcotics If convulsions arise from organic affections we can expect to effect more than to palliate instead of curing the disease. “Counterirritation by mustard, horseradish etc. may be useful” An injection can do no harm can always be administered and if one cannot administer articles by the mouth Irritants may be applied immediately e.g. mustard horseradish garlic N.B. we do not need powerful vesication for the tender skin of infants. Even garlic sometimes vesicates Ammoniae to nostrils & in mouth Be sure that you have [water] enough to [illegible] the child completely for the nerves are apt to think that it is sufficient to half [illegible] child & then sprinkle or scatter water over producing an equal excitement Friction may be applied while in the bath & after coming out [illegible] with dry flannel If the irritants have been applied before the bath taken then off when [illegible] about to immerse in the bath & put them on again if necessary after coming out If the child seems to be in a state of asphyxia the emetic may not take effect; then irritate the fauces the child being lard on its abdomen supported by the hand of the nurse 95 When you are called to a child in convulsions, without previous sickness, direct an injection to be immediately administered and the warm bath to be prepared. if the injection does not relieve, put the child in the warm bath previously adding pearl ash in proportion of zfs to a gall. of water. Let the child remain from 5 to 15 minutes taking it out when it begins to grow exhausted. When taken out of the bath let it be wrapped in flannel & put into a warm bed. Then apply irritants as mustard, horseradish garlic, or aqua ammonia to the abdomen feet and wrists Apply aqua ammonia to the nostrils and temples As soon as the child can swallow give a dose of calomel; If the countenance is pale or livid the cause may be suspected to be some offending matter in the stomach & an emetic ipecac not [illegible] generally should be given. We may often succeed in exciting vomiting by irritating the throat with the finger or a feather & this method should be tried when the patient cannot swallow & is known to have taken improper food or when it is desirable to hasten the operation of an emetic. The child will vomit with much more ease if it is held lying with its belly upon the nurses’ hand, which this supports the abdominal muscles If the child is much agitated at the sight of the water which it is to be immersed, let the tub be covered with a blanket & the patient gradually lowered into the water there will then be no difficulty 96 Epileptic fits are very frequent among children Epilepsy is defined by Good A “spasmodic agitation & distortion, chiefly of the muscles of the face; without sensation or consciousness; recurring at periods more or less regular.” One side is generally more affected than the opposite The limbs may be fixed and rigid with twitching of particular parts. The pupils may be contracted or dilated & the attack may be followed by coma. The attack may be abrupt and without warming or may be preceded by hilarity, or a giddiness or other unpleasant sensation. Sometimes there is what is called the Aura epileptica, a sort of formication, creeping up the body for which the ligature may be applied The fits may be kept up by the constant presence of the cause such as malformation of the brain etc. or, by habit & while in the former case the disease will be incurable, in the latter habit will be very difficult to break up. The causes of epilepsy may be, malformation of the brain tumours of the brain derangement of the system produced before birth by syphilis & rickets or the same causes as those which produce the rickets & in children oftener than after preventing the disease may also arise though more rarely from mere excessive irritability of the system, even’ without any exciting cause of irritation such as indigestible substances in the alimentary canal or suppressed evacuations Among children however epileptic fits are most commonly excited by teething, suppressed evacuations & the irritation of a morbid condition of the bowels or of In scrophulous children remedies for scrofula may be given. [illegible] rickets I have often found advantage from blisters behind the [ears] I have found the cath mode of treat successful for children within the year especially calomel In some cases the most powerful cathartics are required If there is acidity of the passages so that cal. seems to gripe much [illegible] chalk any quantity from 5 to 10 It is immaterial whether the action is chem. or certainly the effect is good The system being very irritable ordinary stimuli or rather a little more than ordinary brings on [illegible] Hence improper articles improper exertions of mind & body etc. Careful management & [illegible] 97 indigestible substances in them. The treatment of epilepsy must vary with the causes which produce it but does not differ materially in the case of children from that of convulsion fits In epilepsy from rickets I have used the cold bath with advantage. In children our attention in the treatment of epilepsy must more especially be directed to the alimentary canal. Cathartics are far more valuable with them than for adults. I have almost always succeeded by means of a course of mild cathartics & joined with one of tonics, such as the tonic solution & the different preparation of iron When called to an attack brought on by offending matter in the stomach and bowels, we should commence the treatment with a strong cathartic in order to thoroughly clear the alimentary canal calomel is the best article but if the bowels are loaded with mucus so that calomel fails to operate we may conjoin 1 or 2 gr. of gamboge & of scammony & 5 of jalap & this though powerful, will yet operate kindly. In the subsequent treatment calomel should be given 3 or 4 times a week; though if there is a deficiency of mucus in the bowels an abrasion as it were the blue pill will be preferable or chalk may be conjoined. Among infants most cases are curable by careful management, both of the physician of nurse The diet should be regulated with great care Generally however there is a morbid appetite, & a sub-[insanity] There is often a difficult, particular waywardness [illegible] like into [illegible] etc. In children more than a year old I have given stramonium so far as to dilate the pupils keeping the child under the operation of it I have not prescribed it to children under 2 yrs or 18 m. I recollect one case in which the convulsion begun to subside as soon as the pupils began to dilate I would not prescribe to [illegible] but to [all] symptoms e.g. tonics all the nat. ton. tinc irr. cap. lead I would give the lead where cathartics, from the excessive irritability of the al. can. aggravate all the symptoms Lead will produce a torpor or sub paresis contrary to this Narcotics also will meet this condition Opium will occasionally, but not generally Why it is we know not but the fact is that phys. do not depend on [illegible] ep. seems to cause a determination to the head 98 with regard to food. This subderangement of the mind manifests itself also in other ways by oddity of appearance gesture & action. A strange propensity for climbing for instance is met with & epileptic children will often be so active & so artful as to be very difficult to manage For more particular treatment see my lecture on m. medical articles stramonium & nit. silver [illegible] turpentine from 10 gtts to zi diluted stramonium, camphor, opium atropa belladonna & most of the more powerful narcotics Arsenic zinc is one of the best of the metallic tonics Actual cautery, [moxa] etc. have been highly extolled “In epilepsy caused by rickets or by the same causes as those which produce ricketts. I have used the cold bath with advantage” “Mercurials followed by mild cathartics [Seontod??] etc.” The child will be still breathing languidly The parents think it dead If you look at it carefully you will perceive as languid treating & looking at the eyes you will often perceive a little convulsive motions of the balls pulse not much disturbed The child continues a few [illegible] with paroxysm & comes out with a scream like an adult from nightmare Not dangerous In a few instances [somerset] Case adult patient [illegible] a chair stands fixed eyes fixed come out with a stare irritable & sub derangement for a few days Afterwards [somersets] “asleep once a sleep twice” Case a girl last year gather up [illegible] [somerset], even 50 times than cataleptic then exhausted This case changed from chorea to catalepsy Repeated bleedings did not change the emaciation etc. 99 Catalepsy This affection when it affects children, is called in poular language still convulsions. It is a very rare disease among adults, but among children I have met with several cases of it In catalepsy the muscles are universally or partially affected with a tonic spasm. The patient remains fixed in the position in which it happened to be when seized appears asleep, is insensible and scarcely breathes. The eyes are commonly fixed, but sometimes have a little motion. The paroxysm may terminate with common convulsions. The length of the paroxysms I have known vary from a few minutes to three hours & in some cases they are frequently repeated The disease arises from the same causes in general & requires the same treatment as epilepsy & convulsions. Cataleptic convulsions sometimes follow other convulsions & in some instances have been brought on by drastic cathartics In adults catalepsy is often followed by irritability & a degree of mental derangement. “Catalepsy arises from the same causes and requires the same treatment as epilepsy chiefly by cath. & antispasm. Sometimes children are affected with catalepsy without it being observed When I commenced practice I thought the notion of still convulsions a mere whim” Dancing before the [illegible] of St. Vitus Dance [illegible] 3 or 4 well persons Comes on gradually parents complain that their children are getting into bad habits Awkward motions The dis. is not benefit. by [illegible] I recollect a gentlem. 40 or 50 yrs told me he had chorea when a child & recollects perfectly the indignation, horror & disgust when so long as to be unable to speak [illegible] Hand carried not to the mouth Sometimes the motions finally become regular “The dancing master” feet blind [illegible] then hands then body then stop like a statue then begin one foot like a [falling] [illegible] 100 Chorea Sancti Viti This is a disease not to be mistaken in its ordinary appearance the voluntary muscles are but partially subject to the well and their motion is convulsive. It occurs oftenest in females of relaxed habit & about the age of puberty especially if they have grown rapidly or been much confined to the needle or to study. In children this disease is often caused by irritation in the primae viae Chorea also arises in some cases from a peculiar irritability of the system in which ordinary stimuli produce convulsive action This irritability may be accompanied with relaxation, or with increased action together with a determination to the head. Indeed it is said sometimes to be connected with inflammation of the brain & hydrocephalus. With those who are predisposed to this disease, particularly if they are females about the age of puberty affections of the mind may bring it or epilepsy sometimes runs into chorea, or alternates with it. Finally, the disease may come on in a very gradual manner, so as not to be suspected, causing a strangeness in the gestures walk etc. which at first is attributed by the friends to the formation of bad habits. This disease is rarely fatal and is not difficult to cure in patients under the age of puberty after that period it is seldom cured. When the disease is of long continuance a great variety of remedies are generally “When I give cathartics in chorea it is not for the evacuation but to produce a new action. All cath. will not act favorably. Hamilton’s views in prescribing cath. are not generally correct.” There sometimes irritation of al. can. from accumulation of feces about the coecum. Hence Hamilton’s plan of purgatives Purgatives will cure but [general] by impression on system It is said to arise from a tonic infl. of brain I have read periodicals have not so I have seen all kinds of treatment tonics, cath narcot. electric. galvan. cold bath etc. etc. Perhaps no disease prescribed for more [illegible] periodically We find one and another article fails and are obliged to go the whole [illegible] off [illegible] narcotic etc. # “In one case of chorea I tried the arnica until the head became affected. The patient began with a decoction of zii the flowers & increased to zfs without any abatement of the disease” Prof T’s [illegible] [illegible] Nux vomica has been used with success in many cases but there are other narcotics which act more powerfully & more certainly I have not used it deterred by [Ba??] [Surrey] who found it injurious for some convulsive cases “Stramonium succeeded in a case following epilepsy” 101 tried and the one last given is apt to be considered as having effected the cure; but I am inclined to think that in many of these cases the disease instead of being cut short by the treatment and run its course and then ceased of itself The most common indications are [for] narcotics and tonics with antispasmodics as palliatives & permanent counterirritation along the spine in some cases. In children however cathartics are commonly indicated; though in general the plan of treating chorea by cathartics, has not succeeded very well in my practice. Dr Hamilton however depended upon cathartics and had better success, though it may be remarked that those who act on that treatment are also the metallic [illegible] When there are symptoms are symptoms of worms, of hydrocephalus, or of inflammation, of the brain or when the disease follows epilepsy we must treat as for those diseases; & if it the chorea is the result exclusively of the peculiar irritability above alluded to, narcotics must be our chief dependance. The principal articles which I have employed in my practice are conium, conium & iron sulphate of zinc, sulphate of iron & other metallic tonics. Various narcotics are used, as the nux vomica in doses of 1 or 2 grs of the seed in pill or 15 or 20 drops of the alcoholic tincture; and antispasmodics as valerian musk etc. may be used as palliatives Cullen’s favorite tonic was the ammoniuret of copper 1 to 4 gr. I have lately used it with advantage in pill 2-3 hours in creasing other tonics are mineral acids, nitrate of silver, bark & the arnica montana #, which is a narcotic & tonic & was successfully used by Dr [Monsen] in chorea” Dr. T’s copy [M. ?] “Sulph zinc 1 gr. may be given 3 or 4 times a day nit. sil. 1/6 to ¼ gr. succeeds best in relaxation of the blood-vessels” “Evacuate the first passages and restore the healthy secretions & irritability of the system by tonics & antispasmodic “I have rarely effected a cure by cathartics though I generally begin with them The cure with antisp. & tonic is slow 2-3 [illegible] with narcotics more speedy but uncertain” A good deal may depend upon the careful management of the patient keeping him quiet & amusing him especially avoiding the irritation of the [pressure] and the impertinent curiosity of strangers The young man in a debilitated “So camphor has sometimes been given in mania to such an extend as to produce epilepsy & sub-apoplexy & this sometimes cures the mania” 103 double the quantity, when the head began to be affected still there was no considerable relief The patient was finally cured by taking the bark in substance zi a day. One case which came on in the gradual manner above described & was brought to a high degree by a dysentery proceeded so far at least as to present the peculiar symptoms of hydrophobia such as horror of water etc. convulsives perfectly [like] that frothing of the mouth etc. died in coma exhausted narcotics tonics etc. no effect excitability exhausted by [illegible] This disease may affect the mind causing it to run upon particular subjects especially upon that of numbers & calculation. I once travelled a short time with a book pedlar who had the odd gestures of chorea & had also this facility in calculation, being in this respect fully equal to the famous [Serah] [Colbourn] [Serah] [Colbourn] though furnished in Europe with the best advantages for education never improved and this result I ventured to predict, when I first heard that he was to be educated. I have seen several such cases. # They have a peculiar articulation & expression of countenance; and are deficient in memory and judgment. Vide [illegible] 12 [illegible] for [Serah] [Colbourn] Case girl at stool good talents studied hard [stand] out of schools [illegible] Cal. narc. cath. tonics operated but [Elateri.] 1/16 gr. once 4 hr in about 24 hours deadly sick nausea prostration vom. purg. disease broken up. It may be diff. to class this A year after similar causes brought on a second attack # Connected with acidity gives great pain not dangerous “This is a troublesome and not unfrequent complaint, arising often from improper food and that stab of the stomach which causes acidity. In a torpid state of the stomach when the healthy action ceases or is feeble, chemical action commences, and the acetous or putrefactive fermentation, prevails according to the contents of the stomach” “If our remedy fails try another for there are no two exactly alike & the judicious physician will discriminate as they are indicated” Among the astringents should be mentioned the rose willow It is one of the pleasantest astringents & is a popular remedy in canker It seems to combine a mucilage Almost any of our wild willows may be used Nitrate of silver may be used It is often however difficult to touch the ulcers and we may then use astringent washes. Rhus glabra and R [typhina] are good astringents vide hosp. [illegible] sub. [illegible] The poison of R [vernex] I have more than once known communicated in more than one instances by using the wood as fuel. I recollect a man’s [illegible] to me on account of an eruption on his legs. I told him he was poisoned. He replied that there could be no cause for it but a pair of the pantaloons lately dyed black. Upon investigation I found that the poison species of sumack had been used by the dyer by mistake for the common one. Young persons are more 102 Cold bathing is sometimes advantageous tepid is seldom proper Electricity has been used. I have seen little benefit from it Setons, issues, tartartar emetic ointment along the spine & other modes of counterirritation, are employed & may be advantageous but where the irritability is great they do injury If the disease is not translatable it is made worse by counterirritation In the treatment of patients affected with this disease, we should bear in mind, that they are the subjects of great mental sensitiveness & irritability The presence of strangers in injurious & the remarks of bystanders upon the patient may cause an amount of mental irritation little suspected. I have succeeded in curing chorea by elaterium though this is an article not mentioned by writers as applicable to this disease. A young man debilitated by confinement as a clerk in N. York was thrown into convulsions and derangement of mind, by a sight of distress while on board the packet for this place Elaterium was given to prostrate the system & break up the habit. It was successful & this led to its employment in chorea. I have completely broken up the latter disease by an eighth of a grain of elaterium & this is the only case which I have broken up vide end of this article Case a female delicate 14 yrs of age had not menstruated had been treated with cathartics, epispasmodics and narcotics, which palliated the symptom. The patient then took arnica for 10 or 12 days beginning with moderate doses (zii to a pint of boiling water being given in 24 hours) & increasing to I have found [illegible] which however was Dr [Rush’s] favorite remedy in females about the cessation of the [illegible] useful Friction antispas. electricity etc. had merely palliated The case then [illegible] to indicate tonics [illegible] the other remedies had [illegible] effect or not recovery rapidly upon bark Sometimes connected with pneumonic affected or with [organic] eff. of the heart In some of these cases [illegible] of copper 1 to 3 gr. rarely more than 2 gr. nauseating article [illegible] in such cases more especially As the [disease] advances sometimes [illegilble] difficult [illegible] swallowing dark [tongue] # [illegible] of them the book pedlar and [Minot] [Sheri] [illegible] [illegible] Both these had this facility in [calculating] # At this time there was not excitability enough left to enable the elat. treat. El. shd not be cont. more than 103:a Ulceration of the mouth in children This is sometimes a troublesome complaint and one that does not readily yield to remedies. It is commonly called canker. The complaint consists of one or more ulcers, which commence with an inflamed point or with a white slough situated commonly near the frenum but sometimes extending over the whole inside of the mouth. The edges of the ulcers are inflamed & elevated & their surfaces excavated, as if they had been eaten out with caustic. The child drools much and nursing is evidently very painful to it. A febricula attends the first stage. The bowels are slow and digestion not vigorous indeed the complaint often arises from improper food and is connected with that state of the stomach which causes acidity Treatment. First excite action of the bowels by magnesia, if there is acidity, blue pill, if there is torpor, or calomel grii & chalk grvi. After this give tonics & astringents as Moseley’s tonic solution 3 to 12 2 to 10 gtts 4 to 6 brak compound tinct. vitriol 4 to 5 gtts & the vegetable astringents as geranium in a [ter] spoonful of water statici spriaea cornus etc. a little laudanum may be added For topical applications we may use the vegetable astringents just mentioned, catechu, kino etc. or the following which has been recommended as very efficacious RX sulph. cupri grs x, cort. peruv. zii acad. gum zi mellis et aquae aa zii make a soft paste to be applied to the ulcers with a pencil. A weak wash of corrosive sublimate may be used Sometimes a mild caustic is serviceable, as nitrate of silver A wash of opium or of opium & corr. sub. is sometimes the best viola pedata makes a valuable wash. Asclepias tuberosa is escharotic. [Post] [illegible] case affected by this poison than old. When young I have often been poisoned myself by boing near the plant merely. Now I can brush past it with impunity provided it does not touch my hands or face. Some persons are not affected at all. The uncertainty of its operation is the only reason why it is not used in medicine. Corrosive sublimate is a good application for the affection of the skin. Yet the disease is a specific one and must generate run through its regular course. A similar disease is produced by the oil of the shell? of the cashew nut Ulceration of the mouth continued “The disease sometimes attended with severe pains, as severe as in tooth ach in which case opium is serviceable. Case of an adult use veg. astring. copper, zinc, opium, nit. silv. & at last corros. sublimate. This last would not be safe in the case of children. Intense pain was produced, which was remedied by holding it in the mouth There was a profuse salivation but it soon ceased and the disease was entirely removed. The surface of the ulcer was destroyed by the sub. & the dis. being local this effected a cure # I have turned my attention particularly to the question whether cal. produces it. I have known the dis. to allow dysentery It was an old notion that cal. broke down the crasus of the blood and it produced a tendency to gangrene. But in the venereal wards of hospitals you will see patients with sloughs all over the mouths and yet no gangrene 104 Gangrene of the mouth This is not a primary disease but a termination of other diseases making its appearance soon after their abatement I have known it follow dysentery and other affections of the bowels, but not any disease in which the blood vessels have exhibited an inflammatory action. It seems to follow diseases of the nerves rather than of the vascular system Children are generally subject of it. This disease is sometimes accompanied with much pain & at others with none ordinarily with little or more. One of the first symptoms is a constant inclination in the child to pick some part of the mouth with the fingers where the gangrene first commences either the teeth gums, less or cheek That part becomes spongy & has a fungous appearance in the course of a few days discharges a [illegible] matter, has a livid appearance & finally becomes black and dry the adjoining parts of the face become tumefied and indurated and the disease continues until a considerable part of the face becomes completely [sphacelated] when the patient dies It may continue sphacelatal in [illegible] etc. the sphacelus being hard dry & black like a piece of leather This disease has been attributed to the use of calomel, but it is entirely unlike that produced by this article, and occurs also in cases where no calomel has been given. # In those cases where calomel has been freely given the disease is not so apt to occur vide case 4th I have known a similar affection occur in the leg of a child, & an irritative fever preceded by rheumatism. Commencing with a spongy and orange coloured spot which afterwards become hard & black, the gangrene livid purpled as though the blood had settled pulse small not much disturbance of the circ. syst. except that it was large # & Prof. Smith & myself could not get down much medicine and were obliged to [illegible] [illegible] with external applications We [illegible] injections and a great variety of external application blisters “When the disease appears with tumefaction I think leeches might be of service. This was called by Dr Smith congestive inflammation. In other cases of gangrene, leeches would not be of service It is not easy to [class] the operation of charcoal It has been called a tonic, but it does not much resemble peruv. bark and we do not gain much by classing it with it It seems to act by generating an excitability Charcoal shd be made of soft wood or of lamp black burned over again in crucible, as is sometimes done by the apothecaries 105 extended up the leg and the child above the knees on both sides died [illegible] No applications seemed to have any effect. The child was irritable & The disease under consideration is nearly allied to that called swelled tongue, but the latter oftener attacks quadrupeds The treatment should be stimulant & antiseptic. Acrids as capsicum may be used & the arum triphyllum accidentally has been known to cure. In one case which I shall relate charcoal appears to have effected the cure. Case 1st The first patient that I saw affected with gangrene of the mouth was an adult female who had the typhus fever. The gangrene commenced on the inside of the cheek & when I first visited the patient a portion of the cheek as large as a dollar had sloughed off out? Great part of the food taken into the mouth passed out at the hole in the cheek. The patient continued in this state for eight or ten days & then died The attending physicians informed me that she has received the ordinary treatment for typhus fever. Case 2nd The next patient affected in a similar manner was a girl seven years of age. Previous to the gangrenous affection she had had a most excruciating disease, which affected the knees legs and bowels I have called it nervous rheumatism & shall notice it in another place. For this she had taken large doses of purgatives 106 calomel & opium, with diaphoretics & tonics. In three or four days the pain ceased and the fever almost entirely disappeared. The guns presented no symptoms of salivation & there was no increase of saliva. In five or six days after the fever subsided the patient complained of severe pain situated in the right temple & extending down to the shoulder like that which had been in the extremities. This was removed by opium to complain of the teeth Soon after she began to work at the molar teeth of the upper jaw, on the right side, at the same time she had a cough which was accompanied with an expectoration of white viscid mucus, and the breath became very offensive, resembling the effluvia of an anatomical room where subjects have been kept a long time. The appetite was tolerable, however the patient took animal food, with relish, and the bowels were easily moved with a little rhubarb the patient world at the teeth until she had removed two of the molar teeth with her fingers, she still continued to pick at the gums. The cheek of the side affected became hard, swollen & red. In forty eight hours a black spot appeared in the centre of the swelling. This spot the patient immediately began to rub with her fingers & soon made a hole through her cheek. The gangrene continued to extend, for a week & at the end of that period had proceeded as far back as the angle of the jaw affected the throat & perhaps the aesophagus The patient then died, having taken food and medicine will until within forty eight hours of her death. 107 Peruvian and oak bark, opium & camphor were very freely given the affected side of the mouth between the teeth & the cheek was filled with superfine bark & poultices of bark were applied to the face In the last stage affected perhaps the lungs Case 3rd Another case occurred in [illegible] subject a child etc. A female child, about 5 years of age was attacked, in the winter of 1813 with “constipation with fever” the complaint being principally confined to the bowels The attending physician gave a dose of calomel and worked it off with senna and manna. A considerable quantity of matter was discharged from the bowels, but from its appearance further evacuations were deemed necessary, and several doses of castor oil were given. On the fourth day I was invited to see the patient. I found her with considerable fever of the typhoid grade, attended with pain in the bowels and head. There was also some swelling of one cheek & the child complained of one or two of the double teeth of the upper jaw on that side. These she frequently attempted to pull out with her fingers & finally succeeded in extracting one of them The cheek afterwards became swollen, inflamed, and hard to the touch & in a short time an orange coloured spot, appeared, upon the outside near the centre, which soon became livid, and the gangrene spreading rapidly, the child died, in eight days from my first visit. She became delirious previously to the cheek becoming livid & afterwards, was comatose. In this case the disease seemed to affect the brain as it does in some cases Bark, opium and camphor were truly given & antiseptic 108 poultice applied to the face as bark [illegible] [fermenting] [poultice] Prof. Smith saw this patient soon after my first visit & agreed with me in the opinion that the case would terminate fatally. He informed me that he had seen but one case of the kind before & that he had attributed that case to an injudicious use of calomel After seeing this patient however, he considered his former opinion as incorrect since in this case there were no marks of the effects of calomel & there was no probability that the single dose of calomel, given in the commencement of the illness, could have produced such an effect, especially when repeated doses of other cathartics, had subsequently been given & had operated freely 4th Case. The next case which I met with was that of a female 12 or 13 years of age, who had the dysentery, in the summer of 1815, accompanied with much typhoid fever & rather a larger discharge of blood by stool than is common in dysentery. The child had been sick for some days before a physician was called. I did not succeed in my attempts to determine the diseased action from the bowels to the surface by diaphoretics & the warm bath, & the disease ran its course and nearly exhausted the patient When it began to decline, the stools to present a fecal appearance & the appetite to return, the friends were There had been some aphthae and I was on a careful watch 109 much encouraged I, however, began to expect a fatal result for I observed, between the anterior incisors of the lower jaw, a fungous enlargement of the gum, the apex of merely a slight discoloration [illegible] & swollen between two teeth which had a purplish appearance somewhat as appears in salivation sometimes. I apprehended gangrene in the case (perhaps from the countenance) and on the first symptoms of it informed the parents, who however, could see nothing alarming in the small swelling between two of the front teeth. I began early with oak & peruvian bark, and at the same time gave freely of brandy and porter. As this course had no effect I applied bark and diluted sulphuric acid to the part affected & also covered with the lunar caustic. Still the treatment had no good effect the gangrene extended under lip and chin became black and the child died Case 5th A child about 3 yrs of age cousin of the previous one [illegible] had a dysentery, in the summer of 1815 [illegible] as there was another member of the family sick in oil uncommon & interesting manner viz the case of chorea resembling hydrophobia was much neglected Her fever was typhoid & the stools sometimes bloody and sometimes of a green mucus. After a course of 15 days and amendment in the symptoms took place the stools became less bloody, the green stools more rare & though the patient was extremely weak but no reduced low as the previous one, the appetite returne After convalescing gradually for six or eight days, there came on a samous discharge from the nose, small in quantity but very fetid which reminded me of gangrene # In this case I examined the gums to see if there was any appearance of salivation and found the gums etc. Two teeth and a piece of the alveolar process came out The disease did not spread so rapidly as the other ones In addition to bark, tonic solution etc. I gave charcoal 110 of the mouth which I had not been on the look out for AT this period the patient inclined to keep her fingers I her mouth. # The gums were very clear and bright & adhered firmly to the teeth, except on the left side of the upper jaw, where the gums of the biscupides appeared discolored and discharged a samous matter. I declared the parents that in my opinion the case would terminate fatally. The child complained of pain in the face and teeth. The cheek opposite the teeth became swelled and hard and of an orange colour. I declared to the friends that mortification had taken place 7 pointed to a black spot on that cheek which happened however to be accidental. I was mistaken for the next day it was found that the black spot was produced by a piece of burnt apple skin, which was washed off This encouraged the friends; yet within 24 hours sphacelus took place the apple skin was in the very spot where I had supposed that I had seen it. This gangrene ceased to spread after the spot became as large as the end of the little finger A circular piece sloughed out and left a hole in through the cheek of about a quarter of an inch diameter The disease abated, the affected teeth and a piece of the alveolar process came away the lips of the wound produced by the sphacelus healed up & the child recovered I recommended the same treatment in this case as in the preceding, but having no confidence in it, & abandoned it and gave charcoal to the amount of perhaps a pound or a pound & a half a day I h ad pudding made of half charcoal & half flour, sweetened with molasses & sugar & fed to the child for the appetite was good. Tonic solution When the disease commences of itself # At the time when the disease called the scalled tongue was very prevalent affecting cattle principally with swelling of the tongue & salivation but to some extent human beings with swelling of tongue cheeks etc. It was found that acrids as [arum] were the best remedies pulse 120 tongue then [brown] fur, considerable pain 111 and compd tinct. vitr. were also given & I commenced the treatment with white oak & peruvian barks & yeast poultice. I attribute the cure, however, to charcoal. Case 6th This was an idiopathic affection. Martha Denison a delicate constitution about 12 yrs of age was attacked in 1819 with symptoms of gangrene of the mouth. There was severe pain in the teeth and jaws oppression at the stomach and symptoms of fever. I discovered the purplish spot in the cheek & “the gums soon put on a spongy appearance” In this case I commenced the treatment with an emetic, which operated favorably I gave it to [illegible] the excitability of the system & gave relief. I then gave stimulants, bark, brandy & opium & kept in the mouth between the gums and cheek a paste made of powdered bark wet with brandy and laudanum. The patient recovered, but the two front teeth of the lower jaw became very loose and there was occasional pain & suppuration for nearly a year. It was about a year before the teeth became firm. [Superfine] bark was occasionally used. Case 7th In 1820 I visited a black child in the last stages of this complaint. At the time when I saw it, it could not swallow. It lived however in this situation for several days I have seen several children in the latter stages Even if there is no chance for a cure it si desirable to be able to give a correct prognosis Trouble has sometimes arisen from the opinion that such cases were produced by calomel A student of this school in [Litch.] cty from notes of my lectures It is known by an [illegible] swelling in the throat some fever etc. etc. In some seasons it prevails extensively & affects persons of all ages. In some seasons these diseases which are called contagious affects one description of persons in another another owing to mode of life etc. “It rarely affects a person the second time. It is said that if it affects the parotid of one side only it may occur again” I have treated cases of this disease with great anxiety. I have never known cases of greater irritation than from this disease “It is milder in children than in adults & is seldom translated to the mammae or testicles till after puberty” “Sometimes the swelling of the testicle is simultaneous with that of the parotid gland or [previous] I have seen several such cases” “The first symptom observed is sometimes a soreness of the testicles. They at length become 4 or 6 times their natural size a suspensory bandage will be necessary” “In some cases there arises suddenly, [illegible] pain in the head pulse full and tense eyes red & all symptoms of phrenitis” 112 Cynanche parotidea Mumps This disease is an inflammation of the parotid glands & is generally moderate in its symptoms Sometimes however it is translated to other parts & is then a severe disease endangering life. It is milder in youth than in adults & in general it is only after the age of puberty that it is translated. The parts to which it is translated occasionally, are the testicles & the prostate gland in males the mammae of females more rarely & sometimes the brain or stomach I have never myself seen a case in which the inflammation was transferred to the mammae but do not doubt the fact Sometimes it appears first in the testicle or at least simultaneously in that & the gland This disease has been considered contagious In my opinion it is not, but on the contrary is liable to be epidemic. When its prevailed in college, the students who left in order to avoid the contagion were attacked as early and is certainly as those who remained. I have noticed that it made its appearance pretty regularly once in seven or fourteen years The fever which accompanies the severer forms is either of the inflammatory or the typhus grade or may be merely irritative & should be treated accordingly When the testicles are affected they are painful swollen sometimes to an excessive degree & sometimes so highly inflamed as to indicate venesection When the stomach is affected “it puts on crythomatic inflammation” and there is hiccough, subsultus tendinum, irritability of stomach and frequent vomiting. # When the brain is affected there is pain of the head & eyes, with hard and tense pulse When the parotid glands only are affected the # These symptoms may come on after the affect of test. [illegible] continued, some [illegible] begin to subside. Dr Rush observes that applying a blister directly on the infl. prevents the system from being affected. I do think blisters keep the aff. in one part “In some seasons an emetic at the commencement or a blister will prevent a translation” Having [learned] the importance of attempting the breaking up of diseases I cast about one year for means to interrupt it & found emetics quite efficacious Stramonium After the testicles have been affected some time and the affection begins to subside the symptoms sometimes change There is subsultus tendinum the stomach become affected vomiting is frequent with hiccough etc. In this case apply mustard to the stomach & feet etc. 113 a generally mild and more inconvenient than painful A translation makes it worse; more so when the translation is to the stomach than to the testicles & most of all when to the brain. Sometimes the complaint is very severe, the fever lasts three or four weeks and the patients are many years in recovering from the disease Treatment. The disease is often broken up by an emetic in the commencement It is best to stop it in the first stages if possible. Mild applications to the inflamed parotids we generally sufficient, such as ammonia or volatile liniment. Dr Rush however recommends blisters to the parts affected, in order to prevent a translation. When the disease effects the testicles & give emetics and apply discutients to the local affection. I also apply blisters to the inside of the thighs. They relieve the testicles when they are swollen & prevent translation to the stomach For a discutient was we may take the following Rx mur. amm. ziii; camph zi; brandy or vinegar 1 gill; water 3 gills. When the inflammatory action is high, bleeding may be practised. It will be well also to use a suspensory bandage. If the stomach is affected in the manner above described we have a difficult case to manage. Epispastics must be applied to the scrotum, counterirritants to the epigastrium to ally vomiting, with effervescing mixtures internally for the Ether is best given in effervescing mixture (carb amm. & lemon juice) Carbon ac. makes stimulants more diffusible & hence causes them to be [used] gratefully and often to be well borne when otherwise the would not be Case 18 grs plethoric parot. gland & testicles swollen head affected Relieved by bleeding decidedly entonic the only entonic case which occurred In the progress of his case stom. became very irritable abdomen sore & tender excessive irritability Did not recover his health completely for years was left dyspeptic & with nervous irritability. To correct irritability of stom. lem. juice [illegible] is most grateful add [doses] of aromatics lime water also external blistering etc. Tonics or metallic tonics myrrh asafoetida (nervine also) hops lettuce These cases are so obstinate and will give you an opportunity to try a great variety of remedies cajeput oil on sugar ol. valerian Though the cases may be apparently alike yet you may find one article best for one & another for [another] A very distressing hiccup, accompanied with spasms might have been mentioned in connection with the vomiting give ether lavender cajeput oil also & valerian which are called terebinthinates 114 same purpose diffusible stimuli as ether given to rouse the system opium ipecac, as tonic stimulant, diaphoretic & nervine 7 finally to allay irritation of the system in general antispasmodics as castor & counterirritants to the extremities effervescing mixtures absorbents, also, as chalk & magnesia, cathartics cantheride & occasionally emetics may be indicated. When the brain becomes affected, the lancet should be freely used, cupping, leeches & blisters, applied to the head of the neutral salt given as cathartics Antimonials nit. [illegible] cal. & neutral salts # Some cases will require a vigorous antiphlogistic course of treatment, others with typhoid fever will require in the [illegible] a stimulating & supporting one, while others again will have symptoms of irritation chiefly & require a corresponding treatment In the progress of the disease uniform perspiration will be valuable Angostura serpentaria, qualified with cardamom or cubebs The old writers recommend also [contrayerva] I have much used it atonics of a peculiar character resembles much agrimonia eupatoria which I have used for it in the country where it is easily obtained the latter is non astringent # “Cold to the head and warmth to the feet avoid mental irritation recovery is usually speedy adults most liable to this translation” I consider [quinsy] an affection of the mucus membranes and [tonsils] nearly allied to catarrhal aff. There is a catarrh aff. nearly allied in which there is a thickening of the membrane. This diathesis may also run into croup Good classes angina maligna with quinsy Here is the evil of nosology For scarlet fever gradually runs into quinsy. We must have science and nosology but still we ought to know the errors which nosology is apt to lend [illegible] & the imperfection of science I have the advantage of not [illegible] having seen the disease but of having had it myself often [illegible] with an unpleasant sensation a relaxation a disposition to hawk and throw off [illegible] In this stage it may certainly be cured After the symptoms comes on swelling, or moderately succeeding to this a chill then swelling with pain perhaps extending to the [illegible] The tonsils enlarge The fever is considered enteric or a common but unless among the labouring men in the country it is more usually subacute One tonsil is perhaps more enlarged than the other perhaps one goes on to suppurate & the other becomes of the natural size and appearance The uvula and fauces swell and respiration and deglutition are prevented. Sometimes ulcers from at first upon the tonsils. Examine each case and do not be too positive in calling it quinsy for this & scarlet fever do blend These symptoms continue 2 to 36 or 48 hours I do not know that I have ever seen a fatal case of 115 Cynanche Tonsillaris Quinsy This diseases has been called “I include also under the term quinsy all effections of the upper part of the aesophagus and pharynx which resemble quinsy in their grade of action” Quinsy is an inflammation seated in the larynx glottis & fauces The characteristic symptoms is swelling of the tonsils Sometimes it is seated lower down in the pharynx than the tonsils, but this does not alter the nature of the disease In some cases it is complicated with catarrh. Those who have once had this disease are very liable to a return of it “The disease common at the age of puberty that before or after” Quinsy may be divided into two stages 1st Predisposing debility indicated by relaxation of the uvula and tonsil, irritation about the fauces, weak deglutition, general languor, with cold chills and uncommon sensibility to cold. This usually continues from 3 or 4 to 12 hours the progress of the disease being sometime rapid and sometimes slow 2nd As the disease advances we find, soreness, pain, redness and swelling of one or both of the tonsils & an inflammation of the mucous membrane of the pharynx; deglutition in exceedingly difficult; there is a severe cough & especially a spasmodic one upon taking food or drink, there is much heat about the throat and about the head & sometimes pain in the head, with a pulse so full and tense as to indicate bleeding. Sometimes there is an excruciating pain in the ear. “rarely cough unless complicated with catarrh” This stage may continue three or four 3 to 7 days days. It terminates either in resolution, or suppuration. of quinsy though I have seen many that I thought would prove fatal. I have known a patient continue unable to swallow for 3 days and yet recover When however it is in the form of swelled tongue it may prove fatal. “An entonic fever may attend, with fullness of pulse much headache excruciating pain extending to the ear; but for more commonly at least in my practice, the pulse is little affected, and the disease is almost not entirely local” # riding on horseback and having the snow melt on his throat & [conduct] off the [caloric] rapidly # and shd carry a piece of alum in the pocket “It is important to distinguish this disease from roseola (scarlet fever) There is an erythema of the fauces distinct from both which yet may terminate in either [illegible] The diagnosis is generally easy but there are cases where it is extremely difficult & indeed there is no definite line believed the two especially in the first stages We must bear in mind that quinsy is commonly more inflammatory that it is not apt to ulcerate & we must be guided somewhat by the prescribing epidemic 116 The suppuration is generally in the tonsils, but in some cases where the disease is seated lower down, a part of the aesophagus suppurates. “The tonsils often remain permanently enlarged” Causes. Quinsy occurs must often in the latter part of autumn & in winter. It is caused like catarrh by alternations of heat and cold by exposure to cold & especially by exposure to cold storms of rain or snow. # Sometimes it is connected with dyspepsia & it may be brought on by irritating substances, as acids, acting upon the mucous membrane of the stomach. I recollect a case of a young man who was attacked with a severe quinsy in consequence of drinking freely of cider made cold with ice Persons who are subject to quinsy should be very cautious about exposing themselves to the alternative of heat and cold # Diagnosis. This disease has sometimes been mistaken for scarlet fever. It is not difficult however to discriminate between them by attending to their prominent symptoms the quinsy being as inflammation of the mucous membrane etc. The first stages however of scarlet fever, resemble those of quinsy, and the difficulty of discriminating between them is at that period much greater. In deciding upon any particular case we must be governed by somewhat by the nature of the prevailing epidemics Chewing camphor will also but not so well break up quinsy in the forming stage but chewing this article is apt to produce pleasant symptoms in the stomach and head Other stimulating applications would probably answer as [guaiacum] & any alcoholic tincture “The prophylactic plan of carrying alum in the pocket etc. has succeeded in hundreds of cases. Indeed when called in the latter stages I often tall them I can do little except to prevent it in future” When the dis is fully formed and when there is much pain in the neck running up into the [illegible] fomentations and the vapour of warm water, the steam bath by throwing over the patients head a blanket and having a teapot of warm water A blister also in the above circumstances will relieve the pain and give great relief An emetic also will be often very beneficial in the commencement of the second stage There is often an excessive quantity of acid in the stomach Case A young man in very hot weather [illegible] a large quantity of cider made very cold with ice was taken at night with great pain and difficulty of swallowing The patient was very anxious to be cured that night A large quantity of tartar emetic was given in excessive doses until a severe orgasm was produced then seeing to [illegible] stricture of the upper orifice of the stomach the [illegible] & secreted from every pore from the violence of the action of the system finally he [illegible] away, and continue in syncope for 10 or 15 mins came out of his fainting fit, the tart. ant. acted as a cath. and the patient was entirely relieved of the difficulty of swallowing [illegible] was merely feeble and exhausted from the prostration of the [tart] 117 Treatment In the first or forming stage. Quinsy may be easily broken up by keeping a small piece of alum say of the size of half a pea in the mouth, and swallowing the saliva until the symptoms have left. Various other astringents may be useful in the first stage. I have given the astringent barks and bitter roots, catechu etc. & have also combined with them the mineral acids chlorine etc. “But all these things will be injurious in the 2nd stage” When the disease if farther advanced a more energetic treatment is necessary. If the tonsils are largely swelled astringents will merely aggravate. IN this stage it may often be broken up by a strong impression made by nausea and vomiting. A strong emetic 3 grs tartar emetic with 8 grs of ipecac # may be given & when the disease arises from a chronic affection of the mucous membrane & acidity of the stomach, an emetic will remove it. In one case I gave half a grain of tartar emetic once in 15 min. until the system was affected, I succeeded in conquering the disease. The patient was in extreme pain & exhausted he fainted previous to fainting he was unable to swallow after coming to, he could swallow & the disease was removed. “But if the case has advanced a little farther, emetic will do no good”s Gargles will in general do harm rather than good, where there is much inflammation. If the irritability is extreme mucilages may be given, and when there is great difficulty in swallowing a cloth wet with spirit and water ay be applied over the mouth and nostrils. Cold water applied externally & internally has been recommended but is dangerous. It may be used however as a preventive. # Eupatorium etc. I have known some phys. generally successful [illegible] breaking up quinsy with cold water but as I predicted there was danger of the translation to the brain he lost one patient in this way “It may be used as a preventive” When the trails are much enlarged it is customary to bleed I would bleed it there was much fullness and strength of the pulse I have often bled and seen it done without the beast benefit still however without any injury as I could perceive “V. S. is important when there is danger of affection of the brain” Scarifying is generally practised. It is sometimes beneficial but often it increases the disease as is the case when a boil is scarifyed I do no t know that I can point out the circumstances which it is beneficial but if there is much irritation I think I would not scarify I have often had my own throat scarifyed without benefit Perhaps it is as often as once in 20 cases that the disease proceeds to suppuration. But if you puncture the swelling be careful to see where you introduce your lancet Case of [young] an opening was made which subsequently caused a troublesome sore the swelling burst of itself In various cases astringents was useful Lister’s [scoriae] (devils bit button snake root) it acts a little like seneka stimulating the fauces it operates considerably in a decoction It has been much used not of much consequence I have not much confidence in gargles The patient cannot gargle But you will give great relief by washing out the mouth with warm water or with mucilages or with a little old spirits and water which is very grateful to the patient Wash off the [illegible] which [illegible] Great advantage is derived from injecting with considerable force with a syringe & washing on the parts Spirits & water will be grateful & reviving 118 When there is redness and swelling but not extreme irritability, scarification is beneficial. If there is irritating soreness or inflammation scarifying will aggravate it After the inflammatory stage is past, blisters may be used I have not been successful in scarifying Bleeding may be necessary, if so it will be indicated by pain in the head and a full & tense pulse. When suppuration is about to take place poultice may be applied externally & vapor inhaled The latter remedy may be administered, very well in the following manner. Put a vessel of hot water in the bed, by the side of the patient & cover him with a sheet. # Touching the tonsils with nitrate of silver, is highly useful If the ear is affected, wet a piece of cotton with strong ammonia and apply it to the dear. it produces a pungent sensation and often gives relief The [liatris] scariosa is used in quinsy in the form of a decoction of the root. It is expectorant, diaphoretic & diuretic. It is called “devils bit” “After the inflammatory stage is established apply blisters” “If the irritability is extreme apply mucilages” “[illegible] & diaphoretics have been used in the early stages and are undoubtedly serviceable” # If you cannot well distinguish where suppuration has taken place, you had better not attempt to open the tonsils When the swelling is great poultices are very beneficial Dove’s [Dury] poultice Devils dung asafoetica Album graicum blown through a quill!! much used by my predecessors in this place Cathartics are proper early in the disease neutral salts if the fever if phlogistic Diet & regimen Give while the patient can drink, nitrous ether & water or a acidulated drink etc. Feed with arrow root etc. for the diet When the inability to swallow has continued sometimes the action is not enteric & the patient shd not be bled nor exhausted by cath. The disease is at this time principally local & from want of food etc. the pulse becomes feeble spirit and water injected into the throat will bring grateful and reviving [illegible] exhausted patient “Apply poultices keep the bowels open with enemata” “Inhale vapour of ether” Various gargles are recommended such as chlorine muriatic acid & water etc. but when there is much action they are apt to irritate Camphorated gargle vapour of camphor etc. There are a variety of these things which are mere palliatives The difficulty of swallowing is not caused so much by the swelling as by the soreness and pain for I have seen patients declare themselves much relieved and able to swallow when upon looking into the throat I could perceive no change in its appearance 119 “Scarification is recommended but I could never succeed with it. If the disease were pure inf. scarif. would be of service but it is an irritation infl. & scarific. increases the pain & infl.” In [illegible] case a free scarific. made the case worse in every respect” There is a stage when scarifying is beneficial when there is redness & swelling but not extreme irritability” “Leeches have been applied in the inflammatory stage externally and to the tonsils. It is difficult to make them take hold on the mucous membrane, but they would be more effectual there” “Suppuration does not take place in one tenth part of the cases. There is free secretion but no solution of continuity upon extermination” “When suppuration is likely to take place use poultices and inhalations of vapour poultices of bread and milk with stramonium are serviceable Gargle or syringe the mouth with spirits & water or camphor” “When the disease is seated farther down in the larynx it is essentially the same” “White dry pigeon’s dung in a poultice with bread and milk was used by Dr [Monson] He thought the phosphate of lime of service” I prescribed it in one case and they mistook for it devils dung (asafoetida) & it did wonders. I did not tell them of their mistake” [illegible] state of fever is a better classification than Good’s. Good separates the disease under different classes making one part are [illegible] disease another an aff. of the blood vessels “Scarlatina & angina are sometimes considered as separate diseases, but they seem to be only different forms of the same disease” 120 Scarlet Fever This disease has been called by various names, among medical writers, though the popular English appellation has been scarlet fever with little or no change. Canker rash however has been its common popular appellation in New England, until of late. Under the name scarlet fever I include both scarlatina mitis & S. maligna & likewise the paristhmitis maligna or ulcerated sore throat called also malignant sore throat & malignant quins. Other names that have been given are Scarlatina mitis & maligna cynanche maligna paristhmitis maligna scarlatina anginosa Enanthesis rosalia is defined by Good Rush a scarlet flush appearing about the second day on the face neck or fauces; spreading progressively over the body; and terminating about the seventh day; fever a typhus. This author divides rosalia into two varieties simples or mild scarlet fever which he considers as being slightly contagious & paristhmitica with an ulcerated throat & a rash not so regular as that of the other variety. This he calls highly contagious Under the name scarlet fever I included both the common mild scarlet fever with a rash & nothing more and the most malignant forms of ulcerated sore throat with the intermediate varieties considering them all as being but different degrees of the same disease This disease with its varieties a naturally associated with pneumonia quinsy influenza etc. Quinsy is an exception persons who have had it are more liable to another attack So too in tropical climates even have what is called a seasoning As a matter of fact this disease is theoretically considered contagious practically not so no precautions being taken the patient not being separated nor the friends and neighbors refraining from coming “The notion of contagion may sometimes be useful in keeping away idle visitors case in Guilford” 121 Scarlet fever often appears as a sporadic and sometimes as an epidemic disease. In general it affects children and women more than men. Dr. Rush’s opinion Some say that the disease never persons over 40 years of age. When epidemic however it attacks persons of all ages, though even then the majority of cases are among children and persons of delicate constitution. In general persons who have once had the scarlet fever are not attacked with it again, still this rule is liable to many exceptions for I have known repeated instances of a second appearance of the disease in the same person. This partial security from a second attack is met with in various epidemics & we may say in general that a person who has had any one of several different diseases the same general diathesis is less liable to have another Scarlet fever is said to be contagious especially in its severer forms The fact is disputed but this is the general opinion. Some fevers are perhaps contagion & among them some forms of this may be so. It certainly, however appears to follow the laws of epidemics and I am inclined to think that the facts which have led to the opinion that it is contagion are better explained by reference to those laws. It is said sometimes to go through the country like the influenza. Like other epidemics, those of scarlet fever exhibit appearances in different seasons, being sometimes milk and harmless & at others highly malignant & dangerous It has occasionally been as # And because blisters applied produced mortification It swept off whole families The fever considered a typhus It is not always so It is sometimes [sub-entonic] always however of a typhous grade 122 as the plague. About a century ago this disease prevailed in this state in its most malignant form, sweeping off whole families. It was called the black canker because the sloughs in the throat turned black & this name, though the influence of tradition, inspires terror in this town even to the present day Since that period the disease has probably been growing milder up to the present time. In 1794 however it was very severe in this town in Litchfield county & over the state more malignant than it has been since. Subsequently to that period adult males have been less affected. The last severe epidemic in this town was in 1803. Though sometimes attended with inflammatory symptom. Scarlet fever as a general rule, is of the typhoid or typhus grade & when malignant puts on the form of typhus gravior or gangrenous state of fever Symptoms. This disorder, when not malignant, nor irregular, commences with ordinary febrile symptoms general disturbance of the functions of the system, chills alternated with flashes of heat & pulse in most cases frequent and soft In severe attacks there is much nausea, sometimes vomiting, pain in the head back and limbs & great prostration The tongue of strength. In 1803 the disease frequently commenced with pain in the teeth or in the ear is the first symptoms In the progress of the disease there is more or less tendency in proportion to the violence of the disorder. In severe cases there is often great heat and dryness of the skin & perhaps the color mordax. In such cases also we frequently with an acrid discharge from the eyes & “When delirium is present it arises rather from inanition than repletion IT is accompanied with subsultus” Swelling of the tonsils is rather a favorable symptom Swelling and suppuration of the glands in the neck haemorrhage for the [illegible] & petechiae may occur 123 nose which excoriates the skin wherever it touches. Irritability of the stomach & vomiting are common & sometimes there is a troublesome diarrhoea. Petechiae may make their appearance. Case at [Hotchk??] town Haemorrhages sometimes take place; & in case of heat on the surface and what Armstrong calls congestive state of the system, a slight haemorrhage from the nose will be beneficial. Finally in the ordinary malignant forms of the disease the breath is very fetid. The epidemic of 1803 was characterised by great irritability of the stomach vomiting & diarrhoea pulse very low and feeble. In this epidemic after obviating the inverted action (of the stomach) stimulants were indicated. The throat is more or less affected from a slight redness to a deep slough. Sometimes there is a high degree of inflammation of the uvula & tonsils at others a relaxation indicating astringents both conditions accompanied with a high degree of tumefaction. A common appearance, in the commencement of the severe form of the disease is that of a white coat upon a part of the tonsils In the progress of scarlet fever, the affection of the throat may be more or less troublesome. It often terminates in ulceration & sometimes in gangrene In three or four days from the first appearance of febrile symptoms or rather on the second day of the fever the eruption appears in the form of a fine rash as described in the definition. In about as many days from its appearance about the seventh day of the disease it disappears Peculiar dulness of the eyes hollow sound of the voice patient appearing much like a night walker The first case of the kind which I saw I had no doubt about The friends had doubted whether he was sick enough to send for a phys. I declared at once that he probably would die. This was a case of pneumonia notha Most resembles measles Ordinarily distinguished readily sometimes with difficulty If scarlet fever is accompanied with a running of the discharges from nose with catarrhal symptoms, and is somewhat distinct in its eruption (hard under the touch under the skin) and such cases occur it cannot be distinguished from measles except by the general character of the epidemic I used to notice in the first commencement of my practice that on the first breaking out of the epidemic the older phys. used to wait and observe several cases before they decided upon the name 124 with branny scales & in ordinary cases the patient is then out of danger. The eruptions, however may vary much & even be altogether wanting the local morbid action being determined wholly to the throat. Ataxic cases will have no eruption. The worst cases of scarlet fever are those which transcend ordinary febrile action. In these the patient is scarcely sensible of being ill, appears dull and languid, his countenance indicates torpor of mind, he has little irritability of mind and is indifferent to surrounding object, his extremities are cold & his pulse small frequent and feeble & perhaps intermitting. Upon examining the throat ash coloured sloughs are found upon the tonsils and uvula. In these cases life is extinguished without any reaction of the system in the course of 24 or 48 hours, unless the tendency to death is obviated by the most powerful treatment. These ataxic cases resemble the ataxic cases of yellow fever pneumonia typhodes etc. which have sometimes been called walking cases The scarlet fever is liable to be confounded with measles, the disease which it most resembles. The marks of discrimination are these. In measles the eruption is less diffused is in pimples or circular dots more pointed & partly distinct & partly in clusters & the pimples produce a palpable roughness of the skin. In scarlet fever the eruption is diffused like erysipelas & consists of innumerable points or specks under the cuticle, intermixed with minute pupulae In some cases the eruption is in irregular patches & in others are uniform flush “Symptoms of pneumonia rarely attend scarlatina” This is one of a series of epidemics. It is usually followed or succeeded by measles & is followed by hooping cough For only it probably existed only as an epidemic now we meet with sporadic cases continually 125 while no roughness is felt, except in a slight degree upon the arm. The two diseases differ also in the time at which the eruption appears. In scarlet fever it shows itself upon the face and arms on the second day, but in measles it is not seen upon the arms till the fourth day. The scarlet fever is distinguished also by the absence of the catarrh, cough & determination to the lungs, suffusion of the eyes & the red and swollen state of the eyelids, which generally attend upon the measles. The latter disease also is generally accompanied by an inflammatory fever instead of the typhus which characterises the former. Still these two diseases of ten blend together so as to make the discrimination very difficult. It is barely possible that they are the same disease, though it may be objected to this view, that scarlet fever likewise is occasionally seen to blend with influenza # Epidemics of influenza are followed by [measles & scarlet] The prognosis in this disease will be obvious upon attending to the malignancy or the severity of the symptoms. In its severer forms it is always a dangerous disease & in its highest malignancy one of the most fatal while in its milder forms there is but little danger. # It is sometimes difficult to determine whether a particular case should be considered as one of scarlet fever, or of quinsy A case of scarlet fever in which there is no eruption & the tonsils are inflamed &swollen can be distinguished from one of quinsy only by attending to the state of the pulse, the prevailing epidemic etc. I have known it appear as an epidemic when it required nothing more than nursing One idea which I wish to impress particularly upon your mind, is that you must investigate the particular epidemic which you have to treat for no previous one will probably have been similar 126 The treatment of this disease must vary according to the diathesis. Epidemics of scarlet fever will differ widely in different seasons & different places & require very different treatment In a country where intermittent prevail the treatment will be different This has been some dispute about using the lancet in this disease. This will depend the degree of inflammatory diathesis. As a general rule emetics are indicated, but not always. Cathartics are generally improper but sometimes are required. In short indiscriminate treatment is as improper in this diseases as in any other. In this milder forms of scarlet fever, we may employ the usual treatment for typhoid fever, & administer those remedies which translate & keep up action and equalise excitement, as diaphoretics, the warm bath etc. For the mildest form it will be sufficient to give mild diaphoretics such as wine whey & elder flower tea, with perhaps a little antimony, acidulated drinks & gentle laxatives As the fever is generally of a typhoid or typhus grade, emetics are of especial importance in its treatment. They affect particularly the mucous membranes and may be repeated in the course of the disease, for the purpose of throwing off the accumulated mucus. The violence of the disease may often be completely broken by an emetic “In some epidemics when there is considerable action cath. of cal. are important especially in intermittent districts Rx cal. & jal. as for remittent bilious fever” “When there is tremor paleness, cold sweats, vomiting diarrhoea, cathartics might destroy the patient We must rouse the patient by counterirritants etc. and then we may go on with the treatment by emetics of ipecac etc. “Dr Rush bled but f.s. is very rarely indicated and in such cases as approach to A. tonsillaris” “Still it [illegible] all forms entonic atonic etc. “If malignant give bark & the min. acids. If the system does not respond give cantharides & capsicum oil of cinnamon cloves or cajeput” 127 at the commencement. All writers agree in recommending them. [Witherin] advises ipecac grs vi & tart. ant. gri for an adult followed by a strong decoction of senna Dr Rush recommends the turpenth mineral 2 to 6 grs with the view of strangling the disease in its birth. Sulphate of zinc is a good emetic & is preferable in the latter stage. It is local in its action & tonic in its effect. It operates speedily and produces less exhaustion. Vomiting by snake root has been practised In the irregular forms of scarlet fever, this practice is more questionable & if emetics are given they must be preceded by stimulants to rouse the powers of the system Cathartics are sometimes needed & calomel is to be preferred The judgment of the physician however must be exercised & the character of the epidemic studied, for great caution must be exercised that the system be not weakened by them & in extreme debility they should be preceded by stimulants. In some epidemics they will destroy the pat.” In some epidemics bleeding may be proper, but the apparent indications for it will generally be better answered by leeches about the throats and [temples] In malignant cases where the powers of life are very feeble no evacuations are to be used. External irritants are to be applied to rouse the system such as ginger mustard brandy a paste of mustard spts. turpentine & aqua ammoniae etc. Internal stimulants must be given Ammonia with bark opium etc.” “Tinct. canth 20 drops once in 2 hours till there is some effect.” “Serpentaria with ammonia acts as a tonic and diaphoretic” Where there is a prejudice against cold affusion with water alone spirits or [illegible] or camphor may be added 128 [illegible] to 4 [illegible] 3 or 4 such as capsicum Capsicum especially when the stomach is debilitated 4 to 5 grs [illegible] Cantharides in 20 drop doses. Ammonia camphor quinine, mineral acids etc. Carb. amm. & cantharides may be given to excite the system & be followed by bark and brandy to keep up the excitement. Diffusible stimulants also may be required, such as chloric or sulphuric ether 20 gtts to a teaspoonful of water for a child. In small children if there is difficulty in getting down medicines the bark may be given by injection, or the body covered with it, by means of a bark jacket. In severe cases, not of the most malignant form, the heat and dryness of the skin are often very great & calor mordax may exist. Cold applications to the skin, especially those of stimulating kind will then be beneficial. The cold bath cold affusion, or sponging with vinegar & water or spirits & water may be used according to circumstances. The cold bath or affusion of cold water may be superseded in case of prejudices on the part of the [illegible] or objections from other causes, may be superseded by sponging the body with vinegar & water If the case is attended with extreme debility and relaxation of the system or if any chills are present sponging must be used & [illegible] with caution. If the cold applications produce a chill or if the eruption comes out irregularly. I should advise the tepid bath to determine to the surface. In the advanced stages of the disease when debility & relaxation are great the vinegar & water should be made tepid & spirits may be added. The rules with respect to these applications are the same as in typhus. In the atonic form of “In children with disturbance of the stomach and pain in the bowels at the same time the eruption not coming out well use the tepid bath It obviates the tendency to convulsions and makes the disease regular In the most malignant forms it is inadmissible” “If there is irritability of the stomach give chloride [illegible] 4 grs 2-3 hours absorbents counterirritants” “In the latter stage of protracted cases emetics of sulphur zinc or copper are very useful” “Withering advises in the typhoid state, after evacuating the stomach & bowels to give senega freely This would be injurious in a malignant case” 129 scarlet fever, the cold bath or cold affusion must not be used IN 1803 I used sponging with vinegar and gave internal stimulants at the same time as min. ac. alc. brandy For children the tepid bath is invaluable in scarlitina particularly in the early stages of the disease and when the eruption is not fully out, or where the eruption is irregular. It is questionable however, how it would succeed in the most malignant form of the disease If there is great irritability of the stomach with vomiting, absorbents and counterirritants are to be used & in malignant cases capsicum, tinct. canth. & care to be given In cases of vomiting saffron & snakeroot If there is much diarrhoea we may give # white decoction with opium, injections of laudanum etc. astringents etc. In ordinary cases, when the eruption has been regular & ends with branny scales, about the seventh day the case is out of danger But when the disease is protracted sulphate of zinc or Moseleys tonic solution is to be given as a tonic. The latter article in a dose from a teaspoonful to a tablespoonful is an emetic in cases of great morbid action. Emetics of sulph. zinc & sulph. of copper have been recommended also of acetate of copper The latter article is also escharotic tonic & caustic. The chlorides chlorates are adapted to this stage of the disease [illegible] [chlorate of potassa] grii to vii “In those cases that require stimulants blisters may occasion gangrenes” “When there is tumefaction of the tonsils use blisters paediluvium & gargle with the mur. ac. especially the [oxymorestic] diluted with 6 parts water” 130 The treatment of the local affection of the throat is of two kinds, external & internal When there is much inflammation about the throat, with the uvula elongated, the tonsils enlarged an inflamed & the pulse full I apply epispastics externally. Blisters, mustard, oil of origanum ol. monard punct. etc. may be applied to the throat Gargles are injurious in bad cases & perhaps of little use in most. Still in ordinary forms of the disease from four to six ounces of any mild astringent acidulated perhaps with muriatic acid may be thrown in by a syringe. The marsh rosemary is considered better than any other astringent. The alum root (henchera amer.) is useful both as a gargle & given internally. For the latter purpose sweeten it & add a little brandy When there is not much tumefaction & considerable relaxation of the parts stimulating garbles are good, as capsicum & brandy astringents may be added. In gangrenous cases quinine is good if it can be got down. In the latter stages of the disease it may be useful to touch the ulcers in the throat with nit. silv. “Vinegar & lemon juice may be used as a gargle” “If the ulcers are thick and leathery apply nit. sil.” “I have seen the brain affected and much spasmodic action subderangement pain in the head and all the symptoms of hydrocephalus with a bloating of the whole cellular membrane pulse frequent & extremely quick and all the marks of irritative actions For 3 or 4 years I have used tinct. dose in 4-5 & sat. tinct. canth. in 10 3 or 4 times a day giving also the tonic solution and keeping the bowels open” “It produces eruptions on the skin, heat dryness & soreness of the fauces febrile action & if continued 8 or 10 days I think it would be useful. I would try it were the disease severe and epidemic, whether I thought it contagious or not” 131 The sequel of scarlet fever is dropsy. In children especially an anasarca and sometimes an universal dropsy comes on after the disease has subsided. The first two cases which I met with were in the severe epidemic of 1803. I treated them according to the direction of the books, with bark & brandy opium & lost my patients Considering this as an affection of the absorbent and nervous system I treated the subsequent cases which fell upon my hands with tinct. cantharides & tinct. digitalis The digitalis allayed the morbid action of the exhalents & absorbents & the cantharides acted as a diuretic. “Give of each 2 or 6 drops every 3 or 4 hours It [opens] [illegible] in these cases the effect of irritative action hence the propriety of digitalis Hanneman proposes to prevent the recurrence of scarlet fever by the administration of moderate quantities of atropia belladonna an article which produces an eruption upon the skin, similar to the rash of scarlet fever. The influence of belladonna, upon this hypothesis is similar to that of vaccination in preventing small pox. The termination of the chain of actions in health in some diseases & if we say nature cures the disease then we may say when the tendency is [inevitably] to death that nature commits suicide. The latter is true of this disease Yet if this chain of morbid actions is broken up by a powerful impression the constitution will take on its ordinary action Scarce any disease is more curable when taken in season yet it would not be proper for a physician to say he could cure all cases then pretending infallibility I shd doubt whether Good had ever seen the progress of a single case. He says nothing about the first stage. The tendency of the disease is to destroy the patient not by infl. or irritation but by suffocation from a foreign body in the trachea The stages run into one another, and yet a phys. watching the progress would naturally divide it into three stages Always curable in the first stage unless complicated with some other disease rarely in the second almost never in the last yet I have known cases cured in the last stage The peculiar sound of the cough is alarming (in the first stage) even to those who have never before heard it Dr [Hesark] I have been told divides the disease as I have done into 3 stages and directs to give 2 grs. tart. ant. combined with ipecac. I shd give for the effect not according to the quantity. I put out 3 or 4 gr and give till the effect is produced rarely over 10 grs 132 Croup This disease has been called in America by the popular name of hives which is probably a corruption of heaves called rattles The name given it by Good is empresmia bronchitis. The most common scientific appellation has been cynanche trachealis or angina trachealis The persons attacked by croup are I have never [illegible] 3 and [illegible] almost exclusively children from 3 months to 12 years old # in one instance I have known it attack a person 60 years of age When it occurs in adults it succeeds other diseases I have known 2 or 3 cups of [illegible] “Croup sometimes though less frequently than most diseases, blends with other diseases as catarrh” Some have considered the disease as contagious, but though a few facts appear to favour the supposition, they are not numerous enough to establish a general law. Croup usually occurs in the winter and spring, when it is brough on by exposure to a cold and damp atmosphere. Children upon the sea coast are more subject than in the interior of the country, because exposed to more variable weather and more frequent [thaws] & notwithstanding the greater warmth of the climate on the seacoast For when the air is filled with vapour, the caloric of the body is conducted off with more rapidity than in a dry atmosphere, even if the temperature of the latter is colder. # It is principally confined to persons under 5 years of age though it sometimes attacks persons of all ages, and It is not precisely entonic or atonic & hence might be called specific in peculiar It is said that in croup the exhalent arteries are affected & in catarrh this [illegible] vessels Whether the different vessels are affected or not there is certainly a different action “I have thought croup might destroy life by coating the entire surface of the lungs with a mucous or membranous coat thus preventing the decarbonization of the blood” “I have never seen croup without more or less spasm; & probably in fatal cases it is always a spasmodic contraction that closes the passage to the lungs which is only diminished by the membrane. I never saw a case on the other hand of what is called spasmodic croup which did not if neglected put on the membranous & inflammatory form” A similar [membranific] inflammation exists in the duodenum 133 Croup is a specific disease of a peculiar kind and is never malignant. It comes on with all the symptoms of pyrexia and consist in an inflammatory affection of the mucous membrane of the larynx and trachea, which causes a remarkable shrill sound in breathing & a ringing cough by which those who have seen the complaint cannot fail to recognise it. The proximate cause is a peculiar inflammatory action of the system, determined to the exhalent vessels arteries of the trachea and bronchial vessels, where there is produced an exudation of coagulable lymph similar to that which forms on the membranes of closed cavities from inflammation & entirely different from secretion of the mucous glands whether healthy or unhealthy. This coagulable lymph which is thus exuded, always forms a membrane which lines the larynx and trachea, if the disease proceeds to a fatal termination, and causes death by suffocation. This appearance is always found in the tracheae of those who have died of the disease. The membranific inflammation distinguishes croup in its nature, from catarrh which is in all its varieties, an affection of the mucous glands Most diseases attack in the night “Diseases are cowards, they mostly attack in the night” Rush. “The peculiar ringing sound of croup is made in [expiration] that of hooping cough is inspiration” # As is the case when respiration is impeded by any foreign body there is a great deal of irritation # when the nose discharges [illegible] [illegible] it bronchial vessels secrete mucus and a new action takes place the patient will be apt to recover # The patient was subject to asthma and the croup was neglected until the latter stages finally died + “I have known this to happen only once In this case the friends were not alarmed because the child had been subject to catarrhal affections & the symptoms received no attention till the last stage” # Frequently appears to be [illegible] in the very commencement of the disease 134 This disease sometimes come on like a catarrh and continues two or three days without any alarming symptoms, until suddenly, & often in the night the peculiar symptoms of croup appear. At other times the first symptom of the disease is a severe paroxysm of suffocation attended with the hoarse & shrill ringing noise made during expiration like air through a broken tube & the peculiar ringing cough. The cough in its progress is attended with more or less of spasmodic action. # It is always dry; and when it becomes loose or when mucus is expectorated the disease is broken up and there is no further danger # It rarely continues so long as five days and is sometimes fatal in twenty four hours. Sometimes, though rarely the membrane of coagulated lymph is coughed up. I have met with but one case + In this the membrane was thrown up three times, at each subsequent time forming lower down than before # No disease resembles croup so much as suffocating catarrh yet there are obvious marks of discrimination The latter disease as I have seen it is not attended with much cough and the difficulty of respiration is not in paroxysms but constant & commence with the disease. The pulse is often quickened and when the system is prostrated may be low. # In suffocating catarrh the powers of life are to be raised by external irritants & excitement equalized by the inhalation of the vapor of [illegible] of warm water etc. “Mustard” “If pulse tense bleed” From the earliest of my practice I have been in the habit of dividing it into 3 stages [illegible] that they are perfectly distinct, but [illegible] person would naturally take this view Quiet between the [per.] apparently not much affected during the paroxysms Between the paroxysms pulse natural & eyes bright. You will know this disease in this stage only during the par. Parents in this place know the disease in this stage and send forth phys. In this first stage, the disease must be broken up by a powerful impression upon the system This may be done many ways Some are partial to a [illegible] & some to another “That which is best administered is best” A local effect upon the stomach will not answer I have relied more upon tart. ant. than any other & found it answer all reasonable expectations. I have preferred it to any other I have occasionally used other [illegible] I have found seneka better as an auxiliary than as a commanding [remedy] 135 Croup may be divided into three stages each of them requiring different treatment. 1st The forming stage 2nd The inflammatory stage & 3d The last or suffocating stage 1st In the forming stage, the cough is severe & hoarse & occurs in paroxysms of from five minutes to have an hour in interval. “There is little or no fever” The pulse is regular and small, & sometimes trembling. The patient is often chilly. In this stage the disease may with certainty be cured “I have not lost a patient & have not saved one in [illegible] when not called till the second paroxysm had commenced” In the treatment of this stage we must depend upon emetics. Large doses must be given moderate ones do no good. A dose should be administered sufficiently powerful to affect the whole system and call into action every muscle. We must be regulated not by the quantity but the effect for we must calculate to overcome the diseased action completely by the operator of our remedy. I have given three grains of tartar emetic to a child three months old, & kept up the action by the large doses of seneka repeated every half hour for six or eight hours Tartrate of antimony is the best emetic to commence with and may be given in a dose of from 3 to six grains of strong tart em. After its operation a constant nausea must be kept up by seneka or some similar article, for some time in order to prevent a return of the disease. The seneka excites a new action in the system. It may be given in decoction. Take zfs or zi of bruised seneka to half a pint of water, & boil away a quarter. Give a table spoonful for a It has so happened that with us the [serpentaria] has not answered so well as tart ant. It acts on the fauces perhaps more [illegible] than tart. ant. but does not affect the system act upon the skin & determines to the surface so well as tart. ant. We have not used it however except in the latter stages & perhaps have not given it a thorough trial Sanguinaria vide p. 212 has been used 50 perhaps a hundred years. Three generations of physicians in one locality have used it and relied on it in croup with as much success as upon other articles These mode of using it was in strong decoction without weight & give a table spoonful until the desired effect is produced till vomiting is excited or the disease is broken up There are however forms of the disease where it fails even in [illegible] “Much has been said of the good effects of calomel Give in large doses 20 – 30 [illegible] acting as an emetic it is serviceable but when catharsis is produced, the emetics would fall in with the catharsis. I never could in such a case make the strong impression on the system what I [illegible]” 136 does once in half an hour or as much as the stomach will bear. Seneka has been relied upon by some as a specific in croup, but it is inefficacious when inflammation is present, being a stimulant, and it is too slow in its operation for the first remedy. After giving it as the first article, other emetics seem to lose their influence; acting as cathartics; but after the violence of the disease has been broken up by other emetics, you may avail yourself of the nauseating & deobstruent effects of the seneka & effect a cure. Dr Rush preferred the turpeth mineral 2 to 6 grs as the first emetic. The physicians in Wallingford for 5 years make a strong decoction of sanguinaria, and give it until emesis or a cure is effected. This article may be used instead of seneka in the way above directed In connexion with these means the warm bath and fomentations may be used as adjuvants. Much has been said of the good effects of calomel in this disease You cannot rely upon calomel for the cure of the disease It is too slow in its operation. Never give calomel until you have broken the violence of the disease After emetics have operated and you have availed your self of the operation of seneca & sanguinaria and the disease still exists, give from 5 to 10 grs of calomel By this producing an orgasm in the system more powerful than the disease & continuing it until the latter be overcome, croup may be cured with more certainty than most other diseases. All diseases should be attended I know that there are some very respectable physicians who rely upon calomel For this purpose they give very large doses and produce [illegible] & [illegible] I should prefer it as an auxiliar. I have often used it but after the emetic or with the emetic or before the emetic A variety of other men [illegible] India tobacco which though not allied in botany are so in their operations The common tobacco is generally applied eternally to the pit of the stomach. Lobelia acrid & emetic loses some of its virtues by drying In its recent state 1 gr will often excite full vom. Indeed I have known vom. prod. by merely chewing the capsules & [illegible] without swallowing by the impression upon the mouth Dose of tinct. 20 drops to a t. sp. according to age Other acrid narcotics as veratrum & colchicum may be used In this forming stage bleeding is not indicative by the pulse, nor by state of the system and you will obstruct your efforts to excite a powerful effort of the system if you bleed 2nd stage In this acrid emetics are injurious seneka is too stimulating Sanguinaria had I have seen all the symptoms aggravated by bloodroot in [illegible] the high entonic stage # “If the disease is complicated with a similar affection of the stomach & duodenum give calomel & other cathartics” 137 to in the beginning & it is owing to the imperfection of or our art that every disease is not broken up in its first stages. When however croup supervenes upon other diseases, it is more dangerous. “Those who practice in the country rarely see the disease in the forming stage. I had one winter 20 cases of croup all in town recovered most of the in the country died” 2nd Country practitioners however seldom see this first stage which I have just been treating of when the tongue is not discoloured, the fauces have a natural appearance the pulse is unaffected respiration natural & ordinarily no inflammation about the tonsils. On the contrary they too generally arrive when the disease is in the second or inflammatory stage the disease has effected in which the bloodvessels the skin is hot and dry, the face flushed, the pulse tense & sometimes full the tongue furred, respiration between the paroxysms difficult tongue furred, respiration between the paroxysms difficult and the cough so severe as to threaten immediate death vide p. 213. In this stage we should immediately bleed from freely from a large orifice the arm or jugular vein freely, even until syncope is produced put the patient in the warm bath & let him also inhale the steam of warm water, and give calomel and other cathartics. # Never give emetics in this stage until after depletion by V.S. when we may give 4 grs. of tart. ant. in a table spoonful of warm water & apply epispastics to the throat” in the commencement apply a blister” I dread to be called in this stage of the disease, for it is the almost always fatal venesection sometimes succeeds but very seldom. I would not apply leeches cupping would be better & perhaps friction might be serviceable. Digitalis has been recommended, but In this stage inhale the vapour cover the child & nurse in a chair with a blanket In this stage cal. & cath. may be given In the first stages I have conserved it very unfortunate to find my patient under the operation of a cathartic It feels as if my hands were tied The excitement is of a different kind from what is wanted And emetics are apt to produce hyper cathartics Where the dis tends to the [illegible] the [illegible] a specific. This is known by the cough being less hoarse, by fever, by constipation fever more intestinal membrane will pass off from the duodenum I was formerly disposed to cure this form of the disease [illegible] & described it as such In the second stage epispastics over the whole chest also diaphoretics and tepid bath When the cough is milder and beginning to be loos after being principally broken up in the first stage give cal. in 2 or 3 gr doses once in 2 or 3 hours In the 2nd stage remedies have been given to obviate the fever & digitalis has been used with good effect It was used as a depressing agent It operates by its narcotic power however. here refrigerants are of little efficacy In what may be seen to be the last 138 I have not used it. It is at best but a doubtful remedy in inflammatory effections though calculate to remove more irritations. Sanguinaria diminished arterial action like digitalis and operates powerfully as an emetic. I have not succeeded with it in the last stages of croup & have not used it in the first. [?ronchotomy] has been proposed, but does not promise much benefit, as the disease is seated below the place for operating. “Dr Smith did not recommend it” After depletion and especially after the disease assumes a bilious form you may give powerful cathartics The pt. begins to thrown his head back death may happen any moment 3d IN the last or suffocating stage* you may give emetics of turpeth mineral sulphate of zinc or even corrosive sublimate to throw off the membrane. Something may depend upon changing the emetics & sulphate of zinc may be tried. The cold bath is said to have been successful in this stage, but the fact is not well authenticated. I have used calomel and the warm bath with advantage. Child of Mr Culver [last] in chronic stage “I regret that I have not tried affusion of cold water in the last stage. It is said to cause the membrane to be thrown off & to procure relief even in the very article of death” vide p. 182 *”In the last stage respiration is constantly laborious head thrown back pulse often irregular & intermittent sometimes strong” Chronic form “Sometimes though rarely the disease is only partially subdued I [illegible] on in a chronic form. Calomel vapour best tepid bath are the appropriate remedies” 139 Angina Laryngea Empresma Laryngitis of Good, q.v. for a definition & an account of the disease In this disease the symptoms differ somewhat from those of croup, though the cough is similar The disease is seated in the larynx glottis and fauces & the characteristic symptoms is swelling of the tonsils. The cough is spasmodic and is excited by taking food with drink in this respect also indistinguished from croup. The disease is more violent and rapid than croup, as the inflammation being seated in the narrow part about the glottis produce suffocation sooner. The respiration is more difficult than it croup particularly between the paroxysms This disease more commonly affect adults The first case that I saw was that of an old man in whom the disease was brought on by exposure to cold after a pneumonia From a relation of his symptoms I prescribed seneca which only exasperated the disease, so that when I saw the patient he was unable to speak or swallow. A small red spot appeared on the tonsils. venesection, epispastics, pediluvium, inhalation of vapor etc. were resorted to with no abatement of the symptoms. Venesection was performed a second time & as soon as the patient was able to swallow, 4 grs. of tartar emetic were administered. Some nausea and vomiting with considerable catharsis followed. The vesication “Angina laryngea is mor apt than croup to recur several nights in succession” “The slough were thick and leathery. Sloughing even under blisters. In one instance blisters did not heal in 4 mo. Lunar caustic applied to the tonsils & uvula & inflamed parts proved serviceable # “In one case of A. laryngea I gave sanguinaria It was too acrid and increased the cough etc. It might do good if we could avoid the local effect of its acrimony” 140 was extensively returned & the patient recovered. Much the same treatment is required as in croup but it should be more prompt and with earlier venesection. For the inflammatory stage comes on earlier and the disease runs a more rapid course Last year this diseases differed in its appearance from the former years It has often followed certain affections of the tonsils called black canker. The tonsils are inflamed in black canker and sometime covered with a leathery crust. This comes off and leaves an ulcer. If the inflammation extends to the larynx, symptoms of croup supervene Case of black canker. Two called in the last stage gave blood root with disadvantage # Still at this late period calomel and other cathartics in large doses produced free evacuations and the child recovered Cathartics appear to do better than emetics. In one case after giving cathartics I used the vapour bath and applied a large epispastic over the whole sternum. Though at so late a period the disease abated. A large slough however was produced by the blister which required three months to heal. The morbid action on the skin being similar to that of the tonsils Vie p. 187 Sometimes comes on with a sudden paroxysm of suffocation sometimes gradually “Distinguished in its commencement from croup by the quantity of mucus in the bronchial vessels” “in the case which I have attended, not much febrile action attended the disease” Proximate cause a morbid action of the lining membrane of the lungs accompanied with a viscid secretion of [mucus] By vomiting the disease may be relieved & apparently cured but may appear again in the course of an hour The quantity of mucus is greater than in any other catarrhal affection” 141 Catarrhal epidemic resembling croup Peculiar catarrhal affection resembling croup suffocating catarrh This disease is characterised by a severe hoarse cough, much resembling that of croup. The disease is distinguished in its commencement from croup by the excessive quantity of mucus in the bronchial vessels which causes the suffocation The disease resembles croup likewise in the mode of its attack which is sometimes sudden with symptoms of suffocation, and at other times gradual with paroxysms of coughing and intervals of perfect ease The turns of coughing are so violent in this disease as to produce a livid colour of the face. The extremities evident determination to the head are cold and the head is hot from the quantity of blood thrown into the vessel of the head by coughing. The evacuation from the bowels are healthy and among children with no disease which I am acquainted affect the bowels so little ass this. The proximate cause of the disease is a morbid secretion of mucus on the lining membrane of the lungs & trachaea with obstructed perspiration. The quantity of mucus thrown out by this membrane in this disease is astonishing After the disease is fully formed, great quantities of viscid mucus may be brought away by vomiting, to the great relief of the patient for a short time, and yet within an hour the patient will appear to be suffocating from the the quantity again collected in the bronchial vessels In the commencement of this disease, the indication is to break it up at once by a powerful emetic, of tart. ant. unless the system The principal indication is to break up the disease by a powerful action on the skin on the stomach the duodenum and the fauces It is best affected by tart. ant. which is more difficult in its action than [ipecac] though is very delicate constitutions ipecac may be practicable # prevent accumulation of [mucus] The bowels shd be evacuated not for the purpose of curing the disease but for the prevention of an accumulation of feces which would be irritating In all diseases of the lungs examine the state of the skin and particularly that of the lower extremities for perspiration upon the upper extremities [only] may be a part of the disease I have known the lives of several patients saved by the use of the vapour bath I formerly [illegible] and used [illegible] for transmitting vapour by transmitting air through boiling water It was old practice to apply cat-skins fowls split open (to the feet) etc. with the intention of communicating vitality 142 is too much weakened to bear this treatment. This is a general principle viz, if possible to break a disease in its commencement by means of a strong orgasm. Often the emetic is to be repeated, and it may ever be necessary to give four or five emetics 1 gr [illegible] tart. emet. each in the course of a day. After the disease is somewhat broken up, and epispastic applied upon the breast will assist much in allaying its violence # If the disease still continues or if when first called we find it fully formed and powerful emetics inadmissible the primary indication will be to open the pores of the skin and keep up a gentle perspiration, by small doses of antimonial wine to which may be added in all quantities of camphor by elix. [illegible] & in some cases tinct opii by fomentations and especially by the warm bath and the inhalation of vapour. To affect the latter object the child may be placed in the warm bath & a blanket thrown both over it and the nurse, so as to keep the child in an atmosphere of vapour. Long continued perspiration invariably relieves the symptoms. I have known an instance in which the skin of a sheep warm from the animals body was wrapped round the naked body of the child with beneficial effect. In small children when the stomach ceases to be excited by emetics the throat should be irritated by a feather or the finger, when we wish to produce vomiting For we must never rest satisfied with merely endeavoring to palliate the symptoms. In small children also the mucus should be wiped out of the mouth by the finger or a cloth This disease prevails most in the winter and spring months & does not occur every year. The first patient that I treated for the disease suffered from it a year. I gave mercurials & finally the silver pill (nit sil) 143 I was puzzled with the first cases of this disease which I met with. Some of them continued for weeks and months I was obliged to use perspiration, by warm bath to vapour bath emetics etc. I determined to break up the next cases in the commencement with tartar emetic repeated until full vomiting was produced walking my patients. This plan was more successful A s a general rule break up all diseases if you can “The complaint is epidemic or rather endemic. It has been mistaken for croup, but it differs As croup formerly occurred no mucus was raised in the earlier stages, and when there was an excretion of mucus we considered the disease cured But of late years the two complaints are somewhat blended. Mucus is thrown off sometimes without permanent relief” “There is often in this disease a disturbance of the brain and nervous system resembling epilepsy or chorea produced by the cough” A distinction was formerly made by some writers and some practitioners, between hooping cough and [chin] cough the latter being a spasmodic cough without the hoop. Such a distinction will not hold good there is no difference “Linneas and Rosenstein attributed it to an insect others to malaria” There had been a very severe winter & no one had left the island for months 144 Hooping Cough Pertussis Called also chincough This is a disease which generally attacks children yet occasionally, adults are the subjects. I have known persons of 60 years of age affected with it. As a general rule also it does not affect persons a second time. I have known about 20 or 30 exceptions & among them was the late president Dwight at 60 years Hooping cough generally appears as an epidemic. With respect to its origin there is considerable difficulty in making up an opinion. It is said to be contagious to arise from a specific contagion which affects a person but once. Dr [Dewers], however, says “We confess that we are inclined to believe that it depends upon causes of a more general and pervading influence that contagion.” Dr Cullen asserts that he has said a disease which though evidently arising from chincough contagion never put on any other form than that of common catarrh. In the tenth volume of the medical commentaries DR Willey gives an account of the breaking out of the disease on Block Island under such circumstances that it would seem that it could not have originated from contagion. When the disease prevails many become effected where every precaution is taken” When the disease has been extensively prevalent I have not been particular about keeping patients apart, perhaps however it is best for prudence’ sake to consider the disease as contagious and to treat it as such. One fact I have noticed that in particular seasons may have the disease who have had it before.” Some suppose that it is contagious only in the first stage others in the second “Some think it caused by malaria or animalcular” “The stricture may be overcome by not attempting to inspire, but to expire till the lungs are emptied the pat. can then inspire without difficulty I have known persons subject to this kind of hooping without cough Adults are sometimes attacked in the night with paroxysms of suffocation they start from bed when the recover their breath there is hooping but no cough, at least at first The more they struggle to catch breath the greater the difficulty there seems to be a spasm of the glottis Let them make no effort to inspire but expire the little air remaining in the lungs & they will bye relieved at once. The disease is liable to recur bathe the feet at night give paregoric wine whey diluents The disease is not described 145 Some suppose this disease a peculiar inflammation of the mucous membrane of the trachea and lungs, others that it arises in the bowels This disease often commences with the symptoms of ordinary catarrh & continues without alteration for some days. Sometimes the peculiar mark which gives this cough the appellation of hooping & distinguishes this disease from every other does not appear until the 3d or 4th week It is impossible however to distinguish the disease until this peculiar hooping makes its appearance. When the disease is prevalent it will be safe to treat every severe case of catarrh among children as one of this disease The phenomena peculiar to this disease may be the described. Several frequent expirations are made in succession by spasmodic coughing, and a full inspiration is then necessary to restore air to the lungs. The air as it passes rapidly into the lungs produces a loud sound called whooping The sound however is made more by the structure of the passage than by the rapidity with which the air is drawn into the lungs I have known persons subject to this kind of whooping, without having a cough caused by a spasm of the muscles of the trachea larynx? to which adults are sometimes subject. (Goods laryngismus?) A similar sound is also made in croup, when the air is expired after the passage becomes constricted The patient is aware of the coming on of a paroxysm of coughing by an unpleasant sensation in the throat, & The cough is violent in proportion to the shortness of the paroxysm 146 it is common for children support themselves during its continuance by changing to a chair or other support near them. During the paroxysm the blood is returned with such violence to the head as to produce a livid colour of the face & often in bleeding at the nose. Very violent paroxysm sometimes in young children terminate in convulsions or death The paroxysms continue until a quantity of mucus is thrown up from the lungs or the contents of the stomach are evacuated by vomiting They are short in proportion to the facility with which the mucus is brought up or rather in proportion to the rapidity with which it is secreted It is the secretion of mucus, not its removal which gives relief to the irritation of the lungs Many suppose that this mucus which is generally in considerable quantity is the cause of the paroxysm of coughing instead of the effect of it. The peculiar irritation of membrane in a paroxysm of coughing produces a secretion of [illegible], and when a sufficient quantity has been secreted it is coughed up like the secretion of tears from an irritated eye and the paroxysm is relieved “The mucus sheaths the part & the ceases” The disease continues from one to six months It is often kept up by habit. The cough is usually more violent by night than by day. Violent cases are often attended with considerable fever and in the worst cases respiration is laborious between the fits of coughing. The disease may terminate by apoplexy or suffocation or by ulceration of the lungs and hectic & sometimes by permanent visceral obstruction “or apoplexy or suffocation” Whooping cough is not dangerous to adults and I have never known a child over two years of age die with it. It is most dangerous to infants and the younger the It is usually dangerous to children within the mouth It is apt to wear out very young children especially if they are of a scrofulous tendency It is frequently accompanied with a morbid sensibility and irritability of mind and hence in the latter stages a change of air and of place is salutary as in cholera infantum The same despondency of mind takes place as in chol. inf. q.v. The disease is a fever spending itself upon the lungs and trachea, and affecting also the glandular system Some phys. think this dis. like common catarrh, is always inflammatory in its commencement, and requires antiphlogistic treatment. But we know that pneumonia may be highly typhoid & require treatment opposite to [enteric] pneumonia. If infl. of the lungs exists the antiphlogistic treatment shd be adopted in its fullest extent I have seen antimony as efficacious in this dis as in pneumonia. In general perhaps mild antiphlogistic diet & treatment will be proper. In some cases I have thought the veins lost their power, and in such cases the blood [illegible] has been prescribed & with advantage It is a catarrhal fever at first and to be treated as such 147 child the greater danger in children under the age two years The anger, to be apprehended from the disease will also depend upon the debility of the child when attacked. The cough may be violent and attended with frequent vomiting yet of the patient’s appetite be good there will not be much danger to be apprehended. A moderate hemorrhage from the nose is often salutary Treatment. If the disease is mild and the constitution good little need be done with the way of treatment. But if inflammatory symptoms supervene with a tendency to pneumonia the antiphlogistic treatment must be adopted. Bleeding will often be advisable. A small quantity of blood taken from the arm proves serviceable. In general greater effects may be expected from the application of a few leeches to the breast or neck than from bleeding at the arm but when decided symptoms of pneumonia appear, & the blood seems to be transmitted with difficulty through the lungs. I would recommend venesection. In this case also the bloodroot will be the best article for internal administration In most cases the disease comes on like a catarrh, and should be treated as such, with mild antiphlogistic regiment [illegible] important part of the antiphlogistic treatment of this disease is the keeping the bowels open. Costiveness frequently attends the disease & should be carefully avoided. In general it is better to obviate this symptom by diet as far as it can be done Begin with antimony in small doses 1l or 2 drops ant wine & in [illegible] For very delicate children however it may be better to give ipecac Almost all the writers recommend vomiting [Best] 148 rather than by medicine. The best cathartics for the indication are those which excite the secretions of the stomach and liver. Sometimes the disease has a tendency to produce congestion of the liver and obstruction of the mesenteric glands and in that case also mild mercurials should be given and their use continued as long as any symptoms of congestion exist. All the medical writers on this disease recommended vomiting in the first stage Tart. ant. is in ordinary cases the best emetic. Sometimes for a child from two to six months old two drops of antimonial wine will be an emetic dose while for another of the same age 20 or 3o drops may be required. In affections of the lungs children will bear antimony better than in those of the stomach and duodenum. In some constitutions antimonial emetics produce (in this disease) a sort of spasmodic stricture other emetics also may produce this effect a symptom which must be relieved by diluents and opium In general antimony in small doses may be given to children of any age, either by itself or combined with a small quantity of paregoric or any other mild preparations of opium. Given in this way it removes febrile action and congestion of the lungs, and determines to the surface When the disease has proceeded with You may see the fontanelles swell in such cases. I recollect a child in the whooping cough going into the country I told the parents not to suffer the child to be vomited. A physician in the country said the child must be vomited of course all the books directed it in whooping cough He vomited the child. It went into convulsions and died # Here insert the recipe for hire syrup or compd sys. of squills p. 150 I have known the lives of some patients saved by this antimony internally had lost its power produced no effect 149 violence for some time and there is much determination of blood to the head, threatening convulsions or apoplexy from distention of the blood vessels, or when the patient has become debilitated vomiting by emetics should not be practises or but cautiously. When the system and particularly the stomach has become debilitated. Ipecac is preferable to antimony, given in emetic doses, or in small quantities as an alterative diaphoretic and antispasmodic. And in the latter stages likewise on account of the debility, sulph. tinc. is a good emetic using 5 or 6 grs. with as much of ipecac If there is not much febrile heat, and there is much viscid mucus in the stomach and lungs, and emetic of squills is often serviceable # particularly I [illegible] phlegmatic temperaments syrup of squills vinegar of [illegible] In this disease if there is danger of convulsions from vomiting, blood root and similar articles should be given. The hive syrup or compd tinct. of squills may be used In children under three 6 months, whooping cough may be much relieved (respiration being promoted) by vesication on the breast. A blistering plaster may be applied but I have more generally used the following. Rx common or mild tinct. canth zi targ. ant zi Dissolve the ant. in the tinct. & apply a linen cloth with the mixture till [illegible] or partial vesication is produce & then dress with simple cerate In this way we have the vesicating & irritating qualities combined. This external use of tart. em. was recommended 20 years ago, in the Lon. med. & ph. Journ. This disease may be cured in its first stage but it ordinarily runs a regular course & the treatment is generally palliative brown mixture You will perceive that this is a strong decoction of seneka and squills, with a large proportion of tart ant. shd be given cautiously 4 to 30 drops Narcotics have been strongly recommended e.g. atropa belladonna & hydrogen of the former for 2 gr of the leaves in powder Alibert recommends the fresh bruised root 150 A popular remedy in whooping cough in Godfrey’s cordial, made of molasses and water with a little laudanum and oil of [illegible] “Hive syrup” (or compd syr [illegible]) is made as follows Rx bruised seneka root & squills zz z8 water lb 8 boil and evaporate one half strain and add honey 4 pts boil to lb 6 Add tart. ant. gr.i to every ounce Give for an emetic 8 or 10 20 drops to a child 4 mo. old & repeat the dose every 15 or 20 minutes until vomiting is produced The “brown mixture” is as follows elix. pareg. zi; ant. wine zfs; ext. glyc ziii pul. gum ar. zii wat. zvi trit. & boil dose from ½ teaspoonful to tablespoonful This has been very extensively used This disease has been prescribed for more empirically than most others; a fact which proves the difficulty of curing it It is a popular notion that it must “run its course” & under the influence of this many parents object to its being prescribed for. Undoubtedly this like every other disease must “run its course,” if it is not cured; but this is no reason why the cure should not be attempted. Ammoniae asafoetida (especially if the cough is kept up from habit) 1st antispasmodics 2nd tonics # An emetic is occasionally administered with advantage “I have prepared this from seneca oil also from gun copal” 151 2nd In the second or chronic stage tonics & antispasmodics are indicated. Sulph. of copper or of zinc tinct canth. cinchona, arsenical solution etc. may be required to rouse and support the system & as antispasmodic tinct. asafoet. petroleum Artificial musk etc. and also the narcotics, as hyoscyamus, conium, stramonium, belladona arnica, opium etc. When the cough is kept up by habit, # asafoet. is often administered to children with advantage. It may be given in tinct. or decoct. & if it cannot be given by the mouth it may be thrown up in an enema, using 10, 20, or 30 drops of the tinct. It is a valuable [illegible] the taste is less unpleasant than the [illegible] Artificial musk or oxygenated oil of amber was first introduced by Prof Hufeland of Jena as a specific for whooping cough and has since been found very useful in other spasmodic diseases vid. Lon. M of ph. J. vol. 1: p.181 van Swieten’s comm. etc. Rx nit. ac ziiifs cl. succini zi. And the acid gradually, ina temperature of 100 [degrees] or in the sun. Prof. Hufeland triturated x or xii grs. in a mortar with a few almonds & diluted with z 5 or 6 of water & gave a teaspoonful every 2 hours to a child a year old. This preparation was very celebrated and very effectual, for a time, but afterwards fail was thought to be ill prepared. The truth was the diathesis had changed. Probably it will be as affectual at [illegible] time I have given the above article in tinct. Rx zii of the oxyg. [illegible] [illegible] lbfs alcohol dose 10 to 12 20 gtts It is much more soluble in ether. I frequently dissolve zi of oxygenated amb. in zi of ether dose 1 to 2 drops on sugar 152 It may be prepared indeed of any strength, to suit the convenience of the physician. Probably gum copal oxygenated would answer the same purpose as amber as there is every reason to suppose that the two are essentially the same amber being gum copal mineralised Case of a vein of olibanum or Frankincense found in S. America. Opium is not indicated in this disease except when it is qualified and its action determined to the skin by antimony ipecac or camphor. Hyoscyamus is better than opium for in the cough it produces no constipation and the tincture is very pleasant. I have not however used it in this disease. Conium has been recommended by writers of the first respectability, but later authors do not speak of it with much confidence. It deserves a trial when other things fail. Alibert recommends atropa belladonna 1/6 gr. of the root or leaves powdered & given in milk I have used I have more confidence however stramonium in the [illegible] & think it preferable most of the narcotics to any other narcotic It is peculiarly calculated to remove spasmodic action depending upon irritability of the system or kept up by habit From the relief obtained by its use in asthma I was led to employ it in this disease and from those cases in which I have tried it I am of opinion that it is a very valuable remedy in it The ripe seeds of the stramonium are best the full dose of these for adults is gr. ii for a child 1/10 gr. or more according to the age Mercurials occasionally blue pill rhub & ipecac enough to keep up a gentle excitement in the bowels Not unpleasant to the taste An old [illegible] Chalmers ([illegible] of silver) recommends sulph. cop. & tinct canth in wh. cough # [ago] more used than any other Lately the ox. bis. has taken its place dose the same used for irritating cough & irrit. of stomach 153 Carb. potash is a good antispasmodic used externally and internally. It is not only antacid & antispasmodic but it appears to me to produce a peculiar excitement upon the stomach and aesophagus, which makes the more susceptible to the impression of other articles. Pearlash zfs & water z8 with cochineal enough to colour the solution has been considered relied on by some physicians a specific. The cochineal merely colours the solution. is an article from which I never could perceive any medicinal effects when used alone. I have tried the experiment & could perceive no medicinal effect from it Tonics. I have given the sulphate of zinc more than any other tonic in this disease, and have experienced the greatest benefit. Sulph. tinc given by itself, sometimes produces spasmodic action, the effect I attribute to its being used in substance & hence I always give it in the form of Moseley’s tonic solution. This preparation is both conic and antispasmodic is easily taken and retained on the stomach of very small children Sulph. copper possesses properties similar to those of sulphate of zinc. It is administered in the low stage of whooping cough. In this place the preparation of it called compd tinct vitr has been used according to the recipe in the 10th vol. Duncan’s Commentaries in doses of 3 to 30 drops according to the age of the patient The oxide (or flowers) of zinc & also bismuth formerly much used in spasmodic cough 30 grs have been occasionally used 1 to 3 grs 1 to 10 to an adult The Peruvian bark is a good remedy in the last stages. The only objection to it lies on the difficulty It sometimes happens that the physician is not called in until the latter stages. As one resort we may have recourse to irritate along the spine It is an opinion very extensively prevalent to that it is of no consequence what kind of food a child takes when he has the whooping cough But great attention shd be given Removal from sea side to country and [illegible] country to sea side either is beneficial 154 of administering to small children, a quantity sufficient to produce any considerable effect. This difficulty may now more be overcome by using sulph. quinine ¼ gr to 1 gr Dr Chalmers of South Carolina recommends a combustion of bark, sulphate of copper and cantharides Tinct. cantharides has been long since recommended for whooping cough. It is useful when the system requires an inflammatory diathesis to be produced. Its action on the stomach is probably similar to that which it has in cases of gleet and leucorrhoea the stomach being in a relaxed state & requiring to be excited to a healthy inflammatory action Irritants, as oil of capsicum canth. [illegible] or ol. orig. or vol. lin. rubbed along the spine have been used in the latter stages. They should be tried when you have reason to suspect that the spinal marrow or the nerves proceeding from it are affected. Attention should be paid to the diet of children in the whooping cough avoiding potatoes, oily foods etc. Change of scene & change of air especially by riding should be resorted to in bad cases, to tranquillise the patient & furnish mental excitement. Sometimes the little sufferers will be excessively irritable constantly worrying and teasing until this is done requesting first one thing & the other to be done. It is the worst of such cases, medicine does little good, even the irritation produced by administering it may counteract its beneficial effects. violent palpitation throbbing of the heart a soft flowing pulse and a jarring feel of the pulse under the finger ([illegible]) (The French call an enlarged heart hypertrophy I object to the [name]) For this I have given nit. sil. 1 or 2? gr. (in the chronic stage of [illegible]) Digitalis & also [languinaria] (tinct. 2 or 3 gtts.) This article is dangerous for children because it accumulates in the system Lead has been recommended I have been doubtful with respect to its propriety in affection of the lungs etc. # Pneumonia typhoides 1815 the system seeming to lose the power of [illegible] the blood and the bloodroot was given to promote venous absorption The digitalis might probably be given in such cases but is not as well adapted. I used the blood root and found as much benefit as could or [expected] from any article 155 If the patient having the whooping cough happen to be teething the treatment recommended for dentition should be employed The patients are very liable to have an inflammation of the lungs from taking cold in any stage of the disease & in such cases the remedies for pneumonia should be administered, such as antimony bleeding epispastics, bath etc. The disease I think sometimes determines to the head & produce a relaxation of the sinuses & [illegible] likewise produces a relaxation of the ventricles of the heart the immediate cause being the violence of the cough In such cases I have used lead, but not in sufficient quantities to enable me to recommend it Iodine has been recommended 2 or 3 doses 3 times a day Nit. sil. languinaria & digitalis When in the progress of the disease the circulation becomes much affected the pulse frequent, soft, flowing with occasional intermission respiration high frequent and laborious, with a bloated and sometimes analogous to # a livid countenance, the blood root has done more than any other remedy not failing in any instance to give relief & palliate sympt & in some cases the relief has been permanent. I gave the bloodroot repeatedly, the last spring, 1815 to my patients in the whooping cough. To a child a year old 5 to 10 or 20 grs of the dried root, according to the urgency of the case, infused in 6 or 8 teaspoonful of boiling water. Give a teaspoonful every hour, until vomiting is produced or the patient relieved. Children Sometimes the dis. will be very mild and yet leave the system in such a state that a slight subsequent disease will carry off the patient e.g. in 1815 the dysentery attacking children would often be very slight and yet would carry off every one who had had the whoop. c. in the spring. The attack would be mild and insignificant of dysentery and yet the pat. would go into a [illegible] very speedily like cholera Elaterium has been recommended I shd be cautious in trying it except in very vigorous children I can speak with confidence of arsenic. Excepting occasionally prussic ac. I know of no remedy which so completely cures the wh. cough except prussic acid in some cases. Case child 2 gtts night & a [illegible] in a weak countenance pale, eyes dull face bloated muscular strength weak muscles soft & flabby Parents much [illegible] cough gone recovered colour & strength upon bark I have known several such cases and have known no ultimate injury result from this practice Yet parents are afraid 156 who had the whooping cough that spring were very liable to be carried off by the dysentery of the following summer none died in 1815 of the disease but many in consequence of it, with hydrocephalus and dysentery Prussic acid dose 1/3 of a drop to begin with and arsenic occasionally cut this disease entirely short; and these are the only articles which I have known do so, without leaving a vestige of the disease behind. The former is a dangerous article to use, from its want of uniformity and strength Fowler’s solution of arsenic gtt more [illegible] is safe but does not answer so well in the first stages. If it makes the patient feeble livid bloated & with swollen lips etc. it must be stopped & perhaps bark administered. It has cured the cough in the second stage. Dose 1 drop 1 or 2 drops twice a day. Sometimes is only palliates Case. June 1815. A child of Capt. Totten’s a boy of 5 yrs of age rather full habit had been affected with the cough for a fortnight before I saw him I found his pulse very frequent soft convulsive & with intermissions face swollen and livid, circulation much increased on slight palpitative [illegible] motion of the body in the symptoms aggravated to an alarming degree by a paroxysm of coughing. Previous t the disease a remarkably even tempered and pleasant child he was not on the contrary very irritable. Trifles irritated his mind, and when irritated, all the symptoms of his disease were aggravated. He took an emetic of ipecac, with The sequels of this disease are numerous Sometimes the heart is affected as above and continues so for years. Sometimes the glandular system is affection. Sometimes the lungs. There is a lady in Philadelphia who had (under my care) suppuration of the lungs whoop. cough now healthy hence never despair The stomach and abd. visc. are sometimes affected in a chronic way requiring dandelion mercurials hop [illegible] etc. It is very tedious to attend children in the chronic stage an account of the excessive irritability When bath recommended Cold bath doubtful. I have known patients killed by being brought from the country and plunged in the sea bath “Good speaks highly of rhus [illegible]. It is given to produce a distinct action on the system which shall overcome the diseased action. It determines powerfully to the surface and has a powerful exciting effect on the blood vessels while it does not produce a determination to the brain. I should not recommend this article and it is so uncertain in its effect. On one person it will have no effect at all, when in another it will cause swelling of the eyes, blindness, fever, & great irritation 157 but inconsiderable & temporary relief. He was directed to take the bloodroot every hour, as much as the stomach In relieved the violent symptoms would bear. It was continued for two or three days, and the palpitation of the heart was much abated, the circulation was less irritated, & the livid colour of the face was gone still did not cure When costive he was benefitted by full doses of cathartics. because the system was [illegible] deranged heart lungs etc. I considered the case a fatal one and expressed that opinion to the parents. The cough and other symptoms continued though in a less violent degree disease chronic an epispastic was applied to the chest very irritating (changed clothes often in the day [child] run upon various subjects) Patients strength began to fail and tonics were given white vitriol bark cantharides Finally the patient refused to take any medicine and was left to his own appetite called obstinately for it took cake for food for several days then baked pears then [illegible] Afterwards recovered but was unable to run “for some years” without a palpitation If this disease should again prevail I think I should atropa belladonna as a prophylactic. As the disease continues the stomach may become very much debilitation and require compd powd of [contragerva] cat carilla etc. etc. “Ledus palustra are narcotic” It is not certain that the dis. did not exist before It may have existed before but no general account given of it. It may have been known in diff. places by diff. varies and it [illegible] have been known than the diff names meant the same disease Diseases are not apt to appear suddenly. Still at this period, there [illegible] cause operating for the increase of the dis. Belly usually large and limbs small Joints unusually large Often morbid cravings of appetite Yet the same causes operating in a higher degree produce cretinism There is no difficulty in recognizing the disease You will be struck at first sight with the large size of the head the blue [veins] of the forehead paleness of countenance as you cast your eyes down you will notice the large joints 158 Ricketts This disease according to Underwood was first noticed in England in the year 1628. It is said to have immediately succeeded the increase of manufactures, when people left the villages to settle in large towns, where they wanted exercise and a pure atmosphere Children are rarely attacked with this disease earlier than the sixth month and not usually until after that period. The symptoms are soft flesh muscles & cell. sub. relaxed general relaxation of the system paleness of the countenance unless the face is flushed with fever, which when it exists is of the hectic kind a fever of irritation pulse, usually quick and feeble, tumefaction of the abdomen appetite and digestion bad tendency to acidity veins of the head [illegible] and blue the sutures of the head not firmly closed head large fontanells unusually open joints large in bad cases all the bones of the system enlarged & softened One effect of the disease is that the teeth are cut later than usual. Ricketty children are usually precocious in intellect. Their mental faculties are developped more early but are not capable however of so much improvement, as those of others. Evolution of the mental faculties does not proceed with the tardy progress of the assimilating function The child learns to [illegible] very early and exhibits an acuteness of intellect beyond his years with the exception however of those cases so severe as to have a tendency to cretinism It is a common saying that very forward children are not likely to live long and the precocity of scrofulous & rickety children may have contributed much to the production of this impression. Too much heat may produce an indirect debility Undoubtedly aff. the brain & nervous system Give mercurials occasionally Do not produce salivation and do debilitate by mercury Frictions are very efficacious exciting the skin The reasons why friction are not more successful is that they are not perservered [illegible] the al. can. etc. The cold bath is the only strengthening remedy which acts suddenly No effect can be produced by any medicine equal to the astonishing effect of exercise & amusement in many cases of chronic aff. of stomach & bowel. 159 The causes of this disease as in some instances a predisposition transmitted from debilitated parents sometimes a syphilitic taint of the parents In others bad nursing the children being kept wet and dirty and confined in close & damp apartments or if the child has been carefully fed and kept clean debility produced by confined air too great warmth, too great variety of food and as some think too much saccharine matter in its diet. Inanition may be a cause. The disease prevails among the Alps and is perhaps there caused by the combined influence of cold and moisture This is a disease of debility nearly allied to scrofula & cretinism affecting the viscera of the abdomen generally, the lymphatics and the [isseous] system. The chylopoietic viscera are probably first and afterwards the mesenteric & lymphatic glands generally the indications are to give tone to the system and excite healthy secretions The diet should be dry and nutritious and such as is not only easy of digestion but rather stimulating and the bowels kept open by cathartics which act on the secretions. A dose of calomel with a little ipecac will be useful. The cold bath should be used every day Take the child out of bed in themorning bathe & return. If the Cold bath of salt water is [illegible] tonic patient be very feeble it should be begun with at of a temperature of about 80 [degrees] and gradually used colder The child bath is equal to all other remedies It is more tonic if made of salt water As a substitute for exercise, frictions will be very useful But exercise in the open air should be like whenever the weather is good in a carriage or on horseback and exercise should be so managed as to afford amusement and mental The [guephalin] [polyapt] & also the gr. marg. (which is less odorous) are also used Their agreeable odor if there is no other advantage will prove grateful stimulus & promote healthy secretions Take the child out of bed and plunge him in water (about 70 at first) and replace him in bed Yet in exhaustion of fever the cold bath gives a shock from which the system will not react but yet in the debility the cold bath is highly beneficial whether we can explain it or not. It may be necessary to vary the tonic And it is desirable to have a variety of tonics to [chorea] from also carb iron & tinct. carb. iron ac. fer. alkaline solut The sulph. zinc is not inferior to iron and is not subject to the inconveniences of iron not producing inconveniences Mosely’s sol. The compd tinct vitr. although apparently [illegible] is yet certain in operation and has been long used in this vicinity A tinct. of potash is thought very useful to rub the body with. It is a popular remedy & has sustained its reputation in this neighborhood for many years Lime water made of caustic lime is more tonic than the carbonate That made of shells is thought better being pleasanter than that made for stores probably not as pure but containing muriate of lime. Be careful to see that the shells are thoroughly burnt so as to fall in powder when 160 stimulus by the sight of scenery vegetations, flowers etrc. The patient may even be benefitted by being carried in the arms into the garden and amused in this manner. It must not be forgotten that this cheerful excitement has a powerful effect on the secretions. Feather beds should be prohibited. They are too enervating, and hard ones should be used in their stead. Beds made of the sweet fern (comptonia [asph??folia]) are popular & do very well. They not only from their hardness check the profuse perspiration of the hectic diathesis, but correct the acid smell of the sweat which is very common. IN general heat should be avoided as too relaxing I have rarely failed of curing the disease by the cold bath as the principal remedy, using tonics however as occasion may require. The tonics which we may use are sulphates Phosp. & mur [illegible] 3-10 grs of zinc & of iron muriate of iron martial flowers of iron etc. and the plan has been tried of applying finely powdered bark eternally in a quilted jacket of flannel. It is difficult to give bark in substance to small children. Astringents may be indicated & there is often a degree of acidity so great as to indicate a free use of absorbents The alkalies as pearlash may be beneficial internally & frictions with pearlash & water zfs to a pint may be recommended. Of late iodine has been given in doses of from 2 to 4 drops of the alcoholic tincture 3 or 4 times a day, given mucilage or other convenient vehicle. This article when persevered in has cured a great many cases. It should be [given] at first in small doses & the quantity be gradually increased or a disgust towards it may be created Phosphate of [illegible] was popular Forgetting that the deficiency of [osseous] matter may be defect in the action of the secretions Though the theory was wrong yet the practice was found beneficial absorbents Give a solution of the acid of about the strength of lemonade The phosporus is preferred to the phosphoric quenches in the water you will then have, not as is too commonly the case merely smoky water but lime water of full strength These preparations are called tonics by Good called stimulants (too loose as use of the word) Long before I had any explanation in [illegible] I thought I observed that these articles created a susceptibility to the operation of tonics apparently as generating excitability 161 It has been supposed that the proximate cause of this disease is a deficiency of phosphate of lime with bones but this is an effect, caused by want of action as those vessels which secrete this substance. The proximate cause, as it is called, is in this case the disease itself. In consequence of this notion burnt bones have been much prescribed. They are probably useful not as supplying the matter of bone but as an absorbent & perhaps as a tonic Acids especially the phosphoric have been given. Phosphate of lime has been used with benefit muriate of [illegible] and barytes were formerly much prescribed. The worst cases are those of children born of syphilitic parents for these tonics mercurials and the cold bath will also be the treatment. I give them corr. subl. 1/30 gr with no injurious effect Nearly allied to ricketts and often as sequel of it ricketts often running into it Sometimes appears with ricketts sometimes afterward Ricketts occur with the year. Scrofula occurs later. Ricketts children are more generally of a scrofulous temperament The tendency may exist in the parents and yet be developed only in the children from the causes of bad food [illegible] pain etc. These swellings may continue in children of 5 or 6 [illegible] or within the year with little or no change but increasing of size in spite of poultices filling the whole neck I have found poultices apparently injurious promoting the relaxation but blisters would stimulate and bring on a suppuration. The pus will not be healthy but curdy and whey like The edges will be ragged, not unite readily, and will leave a bad scar. Scrofula, ulcers are said to be distinguished by a smooth overlapping margin. the disease may continue for months and years with little or no change of it does not attack a part essential to life as the lungs, producing tubercular consumption attacking the liver producing a peculiar atonic infl. I have seen cases of scrofula that were [entonic] They were injured by tonics and benefitted by cal. and ant. They would have borne bleeding 162 Scrofula This is a disease of the lymphatics and affects persons of a peculiar temperament this temperament is characterized by a fair, thin, translucent skin, light hair, blue eyes, sometimes black hair and eyes delicate fullness of lips & nostrils usually texture of skin and cellular substance general laxity of muscular fibre usually delicate organization mental faculties developed early on in ricketts. Person who have been affected with ricketts in infancy are after affected with scrofula in after life. This peculiarity of constitution, when a morbid action is superadded, gives rise to the following symptoms First small swellings appear about the neck, slow in their progress & with an imperfect suppuration. Small holes form in the swelling and discharge a subpurulent, watery and flocculent fluid. These scrofulus ulcers when fully formed are distinguished by smooth spongy and overlapping margins & by very lax granulations. The disease forms tubercles upon the lungs, liver kidnies & ovaria & causes a great enlargement of the mesenteric glands This morbid condition and action may be transmitted from parents to children. It prevails especially in cold and variable climates exists most in large manufacturing towns where it is caused by bad food and air, want of cleanliness all of them debilitating causes It is sometimes also in persons predisposed, a sequel of other diseases particularly of small pox, hooping cough & measles Treatment. more may be accomplished in the treatment of scrofula by diet, exercise, sea air etc. than by remedies. Scrofulous swellings should be treated by Avoid cold vegetables & watery diet give animal food articles containing nitrogen as infants are said to abound more in albumen and adults to be [illegible] “Iron zinc copper silver tonics & antispas. are useful” “Conium 2, 3, 4 grs with carb. fer. 10-20 grs” # “I have used with advantage mur. lime 3-4 drops increased to a tablespoonful & also mur. [illegible] 3-30 drops given in milk & water or in coffee. They are tonic & act on the lymph. & gland. syst.” Articles containing [illegible] In [anthelmint???] vesicular [illegible] F. idealis ([illegible]) (sea cabbage) has been given for worms and some families learn their children to cut it A mucilage may be made F [vesiculosis] [illegible] which with bran has constituted a popular poultice for scrofulous tumours When there is loss of tone & an ill conditioned discharge cantharides with opium is a valuable excitant Never continue any remedy after it debilitates by exciting disgust and nausea Mercurial plaister of the shops (gum ammoniac & blue ointment equal parts) has been much used especially for scrof. [swell.] of the joints In these [illegible] become extensively effective and become spongy A man at the westward was very celebrated for curing scrofula. He used wild violets but was not particular as to which species he used 163 blistering van Heuvel’s child a round of remedies had been tried [illegible] Occasional purging with calomel and rhubarb and ipecac in a pill will be useful Preparation of iron, carbonate of iron with conium etc. muriate of [illegible] 3 drops or 6 and barytes in [illegible] you give a teaspoonful iodine scrophularia mar. [Cistus] Canadensis uva ursi Mr Daggett Havanna Dublin Eliza Collis Vide p. 209 Iron no prep. perhaps are better than myrrh mixture or Jenkins’ pills (carb. per. [illegible] camph.) “Bark & quinine” Different preparations of [illegible] & barytes # Now superseded by iodine. I have seen more powerful affects produced by 4 dr. tinct. iod. persevered in a long “5 to 20 gtts within the year 2-3 gtts ter in die” Various vegetable articles I think very highly Rock rose or Cistus Can. (Helia [illegible] [pity] it is changed) Some years since a person went to Long Island to be cured of scrofula to a family famous for curing scrofula returned much benefitted should his remedies they [illegible] [illegible] & [illegible] always used than afterwards, when [illegible] [illegible] from Havan. neck filled up cured by [illegible] had been salivated W. I. without benefit Eliza Collis scrofulous cough much [illegible] cured by [cistis] vide p. 209. Scroph. maril. has been popular has been much used by empirics I have seen it sold at a great price brought from the west a very common plant It has been celebrated for accelerating parturition probably with out foundation The article has probably little or no power. Yet it is advantageous to know such articles in order to [illegible] [illegible] Two entirely different diseases but are classed together and may be treated together “H. externus is correctly named hydrocephalus” “No fever ordinarily attends. The disease consists in loss of town in the absorbents” Of late iodine has been recommended [illegible] two years since I was called to a patient with had enormously distended [illegible] [upon] gr. cal. & 2 drops tinct. iod. [illegible] recovered Tinct. canth. Face pale and bloated child sleepy and [illegible] I know one child who recovered, but at at the ages of 5 or 6 years died of H. internus. If the patient recovers he is more liable to the acute disease afterwards. Puncturing the membrane has been tried with success, and the application of bandages then supporting the child. It is said that puncturing of the pressure has [illegible] 164 Hydrocephalus Divided into two species externus and internus In H. externus the water is formed between the membranes of the brain (between the brain and its membranes?) In H. internus it is in the ventricles of the brain H. externus make its appearance at birth and is usually born with the child. # In its ordinary form it is fatal (It is almost always fatal when it makes its appearance immediately after birth and always so if born with the child) Stimulating and discutient applications to the head have been recommended. Epispastics are said to be serviceable. (Blisters have been found serviceable they should be kept up for a length of time) Mild mercurials cal. or blue pill & the muriate of lime or sometimes [illegible] pressure by bandaging . If the disease is accompanied by rickets the cold bath is indicated and has been found serviceable I have known one child recover from this disease and other who has been mending under medical treatment for 2 years past. I do not know whether it recovered # H. externus appears to be nearly allied to those watery tumours which affect the spine. In consequence of a partial opening of the sutures of the cranium, or the absence of a portion of one of the bones the dura mater and scalp are protruded by the pressure of the contained water & form a swelling on the outside of the head. Puncturing this tumour is suddenly fatal (is as fatal as the same operation performed on the tumor of the spine. Arachnoid inflammation, arachnitis, apoplexia hydrocephalica (Cullen) encephalitis phrenicula of Rush cephalitis profundu of Good We might multiply [illegible] but perhaps this is sufficient The disease different in different cases A great deal has been written and great deal of confusion exists “In this species of hydrocephalus the effusion of serum is into the ventricles of the brain. This serous effusion is the effect of the disease and not the disease itself & hence it may follow diseases of various kinds. I consider the name very improper” # “The vomiting if it cannot be ascribed to improper food in the stomach is an important symptom in the diagnosis” 165 Hydrocephalus Internus acutus Under this unfortunate name I propose to treat of all those cephalic diseases which are less violent in their action than phrenitis (or are less inflammatory). I shall principally confine myself to the disease as it appears in children “Symptoms different in different cases” The disease commences with the following symptoms (one form of the disease is well described by Dr Quin) vide [illegible] vol 2 p. 315 The patient is languid inactive and drowsy more or less feverish at times apparently free from any complaint (drowsy & peevish at intervals easy and apparently free from any complaint) The appetite is poor and irregular (week) & (Nausea &) in many cases vomiting # occurs once or twice a day. The skin “Exacerbation towards [illegible]” is generally hot and dry (towards evening) and if a perspiration occurs it is partial. Soon after these symptoms. The patient is troubled with a headach. The seat of the pain varies in different cases, sometimes it is confined to one side of the head (Soon after these symptoms commence the patient is affected with a sharp headach either in the fore part or crown) It is a common observation that the headache alternates with the affection of the stomach, the vomiting being less troublesome when the pain in the head is most violent. The pain occasionally attacks other parts of the body (& sometimes principally confined to the back of the neck and the space between the scapulae) At this period the patient is averse to the light, cries much & sleeps little While asleep the patient shows # “The tongue is commonly clean & in this respect this aff. differs from remittent bilious fever, in which the vomiting & febricula are attended with a yellow fur upon the tongue” One side of the face body one arm or one leg more affected or moved often is perhaps a severe a pathogen sump. as any other. This is an indication of paralysis I have known [illegible] patient recover from paralysis 166 signs of uneasiness grating grinding the teeth. starting and screaming in sleep as if terrified. The bowels are usually constipated though sometimes relaxed. The pulse in this early stage does not indicate much danger (These symptoms however are subject to great variations). These symptoms are succeeded by affections of the eyes. One eye is turned in ward to the nose its pupil is dilated The pupil contracted in this early & dilated in the latter stages. Sometimes both eyes at the same time are affected in this way both turned inwards & both pupils dilated. In this stage the vomiting becomes more constant and the headache more excruciating, the pulse is frequent and the breathing quick. # If these symptoms supervene to typhus fever, the pulse becomes more slow Exacerbations of fever take place towards evening. There is often a flush upon one cheek (flushing is usually confined to one cheek) Perspiration if it appears is usually confined to the head and chest. A discharge of blood from the nose at this time relieves the symptoms of fever (& removes the flush from the cheek) for a time & any favorable symptoms. Delirium often takes place at this time and is violent in proportion to the age of the patient All this time the disease is undergoing a change. As the disease advances the pulse becomes more slow and unequal & the patient becomes less sensible to (the pain in the head) his sufferings Lethargy succeeds the disturbed sleep and restlessness of the early part of the disease. The strabismus and dilatation of the pupils increase & the eye loses its sensibility Loss of vision (The patient after sleeps with one or both eyes half closed) The patient in this stage often takes medicine & # “Even in this stage patients have been cured by the strong impression on the system made by tartar em. pushed so far as to produce colic” vide infra Sometimes when hemiplegia takes place the disease puts on a chronic form In the 167 sometimes food will sometimes however he obstinately refuses to take any thing. The bowels for the most part continue costive. # To these symptoms succeed a quick small pulse (almost imperceptible) bad symptoms in the last stage sure forerunners of a speedy dissolution (a difficulty of breathing in many cases the flushing of the face is succeeded by extreme paleness sometimes in this stage petechial eruptions appear on various parts of the body & the patient dies in convulsions or sometimes a hemiplegia takes place two or three days before death The disease sometimes runs through its stage in 4 or 5 days at other times it requires as many weeks. The dilatation of the pupils in some cases does not take place until the last stages & perhaps sometimes not at all. In all cases the proper treatment should have been pursued before strabismus, blindness or coma takes place, because very little is to be done afterwards. A constant rolling of the head & moving one arm and one leg are among the most important early symptoms which indicate a dangerous affection of the brain) The disease sometimes puts on the form of an intermittent. When the disease has terminated in effusion the case is probably always fatal. much dissatisfaction after existed When an ordinary fever terminated in hydrocephalus thinking that the phys. was mistaken at first “I think this disease is rarely an idiopathic affection. It supervenes upon other diseases & generally depends on disease of the stomach & bowels” The disease when from ext. violence may exist without any [pathognomic] symptom 168 Causes external violence teething worms Other fevers forming a crisis by effusion into the ventricles of the brain. Typh. fev. & dysent. in children terminate in [illegible] I have known more than one instance in which it followed [illegible] of hip joiont This is very rarely an idiopathic affection unless it may be considered so when it arises from external violence Vide L. J Pringle on dis. of [illegible] When it does arise from external violence it rarely puts on the same symptoms or the same appearances after death All the diseases of children from infancy are liable to terminate by hydrocephalus & hence it is important to examine all the symptoms which may indicate a determination to the brain & check the tendency if possible Case A girl 14 years of age, had symptoms of affection of the brain from a fall upon the occiput she complained of pain in her head for two or three months before she died & occasionally had regular epileptic fits [illegible] [mouth] The pain the head was relieved by cupping and epispastics to the head, but she finally died in an epileptic fit On dissection the dura mater under the cranium, where the injury had been received was thickened and the vessels were injected with blood. The ventricles contained half a pint of water. Dropsy in the brain Yet the pat. had no dilatation of pupils etc. The dis. put on the appearance of epilepsy occurring once a month. More common in some families than in others 169 Causes. Hydrocephalus is a disease nearly allied to with scrofula & like that seems to run in families. Delicate children in whom the mental faculties are more early developed are more subject to it. Hence the common observation that the child is [illegible] forward that it will not live long I think persons of a scrofulous habit are more subject to this disease & that of the hip joint When there has been no local injury to the brain, the disease commences with affection of the bowels, or it is a sympathetic affection from disease of the bowels In the progress of bowel complaints in children, the [illegible] and the small veins become turgid. This enlargement of the vessels seems to invite the blood to that part. In consequence of this child may die with symptoms of hydrocephalus, from the turgescence of the vessels, without any effusion into the ventricles In typhus fever, in dysentery and in other bowel complaints of children it is not uncommon for children to die with symptoms of hydrocephalus It is a good symptom in hydro. to have a discharge from the [sch??der???] membrane 170 Diagnosis “In its early stage, this disease is scarcely to be distinguished from remitting fever When from the anxiety of relatives & of the physician, a diagnosis is eagerly desired, the following circumstances may perhaps assist in forming a judgment If there is occasional vomiting, with febricula the tongue at the same time remaining [illegible], there is reason to apprehend that the primary irritation has its seat in the brain and that it will prove a fatal case of hydrocephalus. But if along with the fever and vomiting the tongue is covered with a thick yellow fur, we may hope that the complaint is confined to the digestive organs and that the disease is nothing more than coler or remittent fever.” Ed.reviewer Diagnostic symptoms between idiopathic arachnitis or cerebral fever, and infantile remittent or fever from intestinal irritation choler In cerebral fever the abdomen is flattened, not tumefied but in intestinal fever it is tumefied. In idiopathic cerebral fever the secretions of saliva and that form the schneideran membrane are diminished. Unless complicated with aff. of muc. m. which is rare. In cerebral fever the tip and edges of the tongue are red In intestinal covered with a thick fur. In cerebral fever the pain in the head is severe and excruciating; in fever from intestinal irritation it is obtuse. # the sides of the head, back of the head on the forehead Perhaps a constant rolling of the head & movement of an arm & leg are among the most important symptoms Different opinion ben entertained about the nature of the disease Some have been so anxious about determining the exact nosological nature of it disease as to refrain from prescribing until the first stage has gone by. Prescribe for the symptoms at all events and make up your mind about the nature of the affection as fast as you can. Too much discrimination cannot be exercised & cultivated yet where we cannot determine the exact nature of the disease we had better treat the existing symptoms & the obvious indications # It varies in scrofulous constit. there is no such state It may approximate in some cases And I might cite the opinion of 20 others The [illegible] it is sometimes entonic & sometimes tonic. It more frequently [illegible] determined Why shd not fevers terminate in the brain as well as [illegible] 171 In intestinal fever the patient more frequently directs his hand to the nose & about the face in cerebral puts his hand to his head # In cerebral affections the head is hotter than the abdomen; but if the disease originates from the bowels the abdomen is the hottest. “There in a very few cases seen picking at the nose in cerebral fever but in general the rule holds good” “The state of the bowels is not pathognomic” Dr Beddoes thinks the disease belongs to inflammations & that at an early period he should be inclined to bleed as largely as in pneumonia # Dr Withering observes “in a great many cases if not in all, congestion or slight inflammation are the precursors of aqueous accumulation Dr Rush thinks that instead of being considered an idiopathic dropsy, it should be regarded only as an affect of primary inflammation or congestion of the brain “Dr Rush says” It appears that the disease in its first stage is the effect of causes which produce a less degree of that inflammation which constitutes phrenitis & that its second stage is a less degree of that effusion which produces serous apoplexy of the brain Dr Darwin supposes torpor or inactivity of the absorbent vessels of the brain to be the cause of H. internus Dr Whytt in his treatise on the disease observes that this and every kind of dropsy depends upon the fact that more fluids are thrown out by the exhalants than [illegible] the absorbents take up I chiefly depend upon calomel for a cure if it cause too much evacuation check it with opium There is no evacuation from the brain therefore the disease must be overcome by altering the secretions counterirritation etc. Bleeding with leeches from the temples seems to translate to the surface and give relief vide John Hunter. Case young man apparently as desperate a cure as ever I saw not scrofulous we concluded to try tart. emet. gave it without much weight in about 8 or 16 hours he complained of violent pain ion the bowels and all the symptoms of the head were relieved [illegible] “Irritant to the schneiderian membrane in the last stages are recommended by Dr Malachi Foote of N. Y. in the Med. Rep. for about 1810. Turpenth min. 1 gr. with liquorice 20 grs [apreynum] [myrici] ipecac etc. are the best [stermentatories]” 172 Treatment Evacuants Bleeding general & local cathartics calomel and jalap gamboge Counterirritation local bleeding cupping epispastics behind the ears and to the whole surface of the head Salivation should be induced but cal. often relieves without altering the secretions There has been a difference of opinion as to the application of epispastics to the head. If venesection be indicated they should not be applied until after bleeding. I prefer cupping and blisters to the back of the neck and behind the ears I think some advantage may be derived from applying to the spine ol. orig. ol. capsc. etc. Where considerable entonic action has existed I have cured this disease by giving tartar emetic until colic was produced. give perhaps a grain & continue its exhibition until the symptoms abate # “gr doses every 2 or 3 hours” Sneiderian membrane dry snuff malachi root Irritants applied to the schneiderian membrane have cured the disease in its last stages Rx 1 part turpenth mineral & 10 parts powdered liquorice for a [ster??tatory] Green tea is sometimes given In the progress of the bowel complaints of children the sinuses may become enlarged & a determination of blood [illegible] to the brain and produce symptoms of hydr. I have known pat. apparently die of hyd. & yet upon dissection no water be found in the [ventricles] in this case some say that the water was absorbed in death this is entirely improbably. Certainly many of the symptoms of hydr may be prod. by other causes e.g. excessive doses of narcotics is stramonium belladonna It shd be remarked that many cases supposed to terminate in hydr. in cases of [termination] in volvulus “All the diseases of children are peculiarly liable to terminate in hydrocephalus. Hence the importance of caution on the part of the physician. He should examine all the symptoms to check the first beginning of determination of diseases action to the head V.S. keep the bowels open blisters behind the ears cupping leeches” 173 Hydrocephalus from bowel complaints If in the progress of any of the bowel complaints of children morbid action should be determined to the brain, Epispastics should be applied behind the ears and irritants to the feet Cathartics are useful to obviate this determination. # In some cases perhaps the determination [marise] from nervous irritation. In such cases the tepid bath gives relief “Strong green tea” Some physicians of respectability have in formed one that they have used digitalis in hydrocephalus with very good success. I have not used it myself but should consider more adapted for that form of the disease which arises from irritation, than any other Hydrocephalus from disease of hip joint. Child of Ezra Hotchkiss child of Horace Edwards. “I have known hyd. alternate with disease of hip joint Case Narcotics etc. till suppuration” Afterwards died of hydrocephalus # I have cured a patient by giving him calomel and lemon juice in sufficient quantity to move the bowels. It increases the secretions and improves the tone of the bowels “I have seen a case in which the child fell 8 or 10 feet upon a pavement & broke his skull like a squash shell yet he recovered in 2 weeks and did well. When the fracture is so extensive there is less danger of compression of the brain” The same case? Hyd. from injury by a fall is not common in young children the sutures are not firmly closed (the bones are softer & more yielding)( # He had other severe wounds as a compd fract. of the radius yet he never suffered his head 174 When the disease is produced by violence Depressions of the cranium in children from blows or falls are not of course fatal though dangerous. A child four months old fell head foremost upon the hearth striking upon the vertex. The head was much flattened & the parietal bones bulged out on each side. The child did not suffer much from the injury. The bowels were kept open by mild mercurial purgatives. In these the head assumed very nearly its natural shape. A boy of eight years fell six or eight feet and struck his head against a stone A depression of the cranium was made larger than the bowl of a spoon. He suffered very little inconvenience from the injury # There is less danger when the skull is so much fractured as not to cause pressure upon the brain If a child has received a fall we may apprehend danger from the following circumstances. If the fall has been upon the occiput the brain is more commonly injured than if the face is upon the os frontis. If the child vomits after the fall and is very sleepy there is danger that the brain will suffer. Treatment If the child vomits or is comatose after the fall upon the head and there is no wound that bleeds the patient should lose blood and take a dose of calomel, one or both according to the urgency of the symptoms & the death of the patient. All the exciting causes of fever should be avoided and the patient kept as quiet as maybe. The symptoms should be carefully watched and if at anytime there should appear to be a tendency to an affectation # for local bleeding is as important a general bleeding “[illegible] all causes of irritation, as light noise heat, food. Keep the pat. perfectly quiet” “Apply an epispastic behind the ear, or better upon the injured part.” “Blisters are very useful” “Use counterirritation & the tepid bath” # In torpor of the br. [illegible] al. can excite the latter may excite the former and excessive action in the former may be translated by it act on the latter “Give strong cath. cal. gamboge jalap etc.” “Afterwards give cal. in small doses as an alterative If it causes too much evacuation check it with opium” “In N. Haven we have followed Abernethy’s plan of treating infl. of brain for 40 years” 175 of the brain the patient ought to be bled & leeches or cupped. # The bowels should be opened with calomel and small doses of the same remedy frequently given as an alterative After depletion epispastics may be applied behind the ears and upon the part of the head where the injury was received. There is no outlet to the brain & consequently more evacuants are needed than in most diseases Frequent cathartics are useful as evacuants and also to translate action from the brain # When effusion has taken place the case is probably always fatal Yet I have had a pat. with dil. of pupils, who cont. so & paralytic for months & finally recover Vide p. 200 The treatment consists of local applications A variety are used One of the best is [illegible] zii alc. zi An equally good or a better application is seneka oil but the smell is disagreeable. Cold water is applied but though it relieves the pain and the insupportable itching it is doubtful whether it is of any permanent benefit Basilicon [illegible] [illegible] absorbents to ulcers 176 Chilblains Pernio This is a local affection to which children and old people are most subject. Some are much more liable than others. [illegible] [illegible] more liable. The parts affected are the toes heels fingers, hands face, ears and with ladies who wear short sleeves in winter. It is caused by exposure to extreme cold & to cold & damp air & on the feet, more especially by walking through melting snow. It is most common in the early part of winter This affection should be prevented by avoiding an exposure of the parts to the air, by keeping the hands warm with soft leather gloves & by keeping the feet warm with stockings and shoes The skin of the part affected becomes tumefied and hard & of a deep purple colour, there is a pungent pain in the part accompanied with an insupportable itching; & these are often so great as to prevent the patient from sleeping. If the disease advances, the cuticle breaks and discharges a thin fluid. Sometimes a deep ulcer is formed The treatment for the first stage should consist of stimulating application as if for a burn. I prefer oil of origanum alcohol & seneca oil are good applications. Spirits of turpentine will ordinarily do well, though in some idiosyncrasies it acts as a poison. Cologne water may be applied or alcohol two parts with one of ol. orig. # For the ulcers you may use the oxygenated ointment ointment of red precip. citrine oint. # or apply a plaister Dyachylon or Noel’s Not being able to have any fire on board for some days [illegible] to pain of a neuralgic kind as [illegible] were a toothache One of the best applications is a cataplasm of stramonium seeds give internally opium narcotics & stimulants Apply [illegible] & narcotics Followed by no infl. to supp. etc. 177 Painful affection from cold We sometimes meet with a painful affection of the feet without discoloration, or any other visible mark, which has been brought on by long exposure to cold without freezing. Sailors coming upon our coast from the I. in winter, from a warmer climate are liable to it. The affection may be a very painful one and give great uneasiness both night and day It is relieved by the external application of stramonium & epispastics or rubefacients, and fomentations Cathartics and opium may also be given internally. Singular effect of cold in Wm Daggett Burns are dangerous in proportion to their extent [illegible] young physicians are called to prescribe for burns it is important for them to treat them in the best manner About 30 years ago a great controversy existed in England between those who advocated [stimulating] In recent cases stimulating or exciting applications are the best provided the burn is not very deep. About 30 years since spts turp. were much used. It in some case and these are not very rare Case myself [water] boiled over into my shoe I immediately poured spts tupr upon the stocking then took off the stocking applied a cloth dipped in spts turp. put on a dry stock. & boot rode out of town and suffered My father was a man of florid complex. & thin skin He was burned in n a similar manner Ol. orig. Linseed oil is smooth mixed with limewater alcohol or proof spts good when the skin is [illegible] off Others use camphor Others stramonium in ointment contain what [illegible] when the article s off Carrot poultices etc. exclude the air Cotton does well except when the cuticle is off if it is used then you had better smear it with oil 178 Burns This subject belongs more particularly to surgery, yet as burns occur most frequently among children, and you may be suddenly called in on such an occasion, when it is important that a remedy be speedily applied. I have thought proper to make some remarks on the subject. For the treatment of burns very different modes have been recommended. A long controversy was carried on in one of the English journals with respect to the phlogistic or antiphlogistic treatment, one party being in favour of cold applications in cold water and the other of stimulating ones as spirits of turpentine The truth seems to be that in adults where the injury is not extensive and the powers of life are strong cold applications do well, but they are dangerous for children especially if the injury is extensive. Burns upon the abdomen will not admit of cold application even in adults It is necessary that reaction take place If there be no reaction of the system, no pain, no inflammation the child dies. The cause of its death is the irritation of the nervous system, extended to the stomach, & hence the death is preceded by cold extremities and vomiting Where cold application are proper such applications may be made as scraped potatoes, cloths wrung out in cold water etc. But if it is necessary to produce reaction and inflammatory action stimulating remedies must be used. And we know from experience that these remedies do effect a speedier cure Cold applications may do well if immediately e.g. dip a burnt arm immediately into cold water. But stim. app. are better. I have tried both. Cold applic. very dang. in extensive burns of children Case scarped potatoes no infl. livid appearance of the burn extrem. cold [illegible] death In such cases apply stim. app. & give ether, elix. [illegible] etc. etc. In these cases the child dies of irritation not infl. It seems to be necessary for a regular [course] of continuity of action in infl. & suppuration The best and mildest application as has been proved by experience is petroleum or seneca oil In one case I tried the experiment of applying seneca oil upon one hand & ol. orig. upon another (both being known alike) one hand was easy the whole night the other painful (the burn was a very extensive from the clothes taking fire) In the suppurating stage use 1 part seneca oil & 3 parts cerate These cases are very troublesome to treat In the above case the system was exhausted by the extensive suppuration the bowels had to be kept open & large quantities of opium to be given. I gave columbo bark and various tonics and aromatics Turner’s cerate is a good application chalk may be sprinkled over it In the progress of the suppuration a pale flabby fungus almost like a blister and is difficult to manage I have applied a sol. nit. sil. also nit. sil. & laudanum [illegible] cop. sometimes after these I have succeeded with ac. op. in ointment green basilicon i.e. verdigris ground fine & mixed with basilicon But if you apply only applications after these caustics 179 The reason is that we apply to the part a stimulus less powerful than that which produced the injury and thus render the diminution of the excessive excitement gradual. On this principle holding the injured part near the fire is beneficial Another important indication in the treatment of burns is to exclude the irritation of the external air Hence the popularity of some applications as cotton. sweet oil etc. 1st Of stimulating applications. Spirits of turpentine will answer for a robust and healthy person but not for a slender & feeble one; and it must be remembered that from a peculiar idiosyncracy it is a poison to some persons. In general spirits of turpentine is liable to cause irritation and may be suspended by better articles. Being burnt myself a complete cure was effected without the least appearance of inflammation, by this article but in the case of my father such violent irritation was produced as to oblige him to desist from applying it A common remedy in this town is the oil of the origanum majorarum called burn oil mix ol. orig. zii with ol. oliv. zi or mix it with alcohol or cerate. Cloths may be dipped in the diluted oil and kept constantly applied Of late years I have used seneca oil and prefer it to either of the two already mentioned. In several cases I have tried both this and the ol orig. & found that the seneca oil relieved more speedily & with less irritation. I usually apply the seneca oil & the fungus [illegible] Apply rather chalk or fine alabaster or scorched flour The sooner you apply stim. appl. the better ol. turp. produces [illegible] etc. seneca oil does not Case a woman thief etc. etc. we rolled immediately in the snow was thrown by it into a state of syncope life almost extinguished was burnt universally except on the legs covered by the stockings was wrapped in sheets dipped in a mixture of ol. orig. & spirits 180 then cover the part with cotton to exclude the air. I let them remain till suppuration takes place, particularly if the skin is broken. When suppuration takes place, apply a poultice to the loose dressings and then apply simple cerate or a cerate made by melting together beeswax and lard and stirring in seneca oil while the mixture is cooling This last is an admirable application for burns Dr [Mons??] said he knew none so wild. It protects the raw surface from the cold air and keeps in the animal heat In the latter stages of the cure, the oxygenated ointment will be a soothing application A popular remedy is stramonium, used in the form of a plaister of the seeds or leaves. It answers well and I have known no ill consequences to happen from its use though it is said that in extensive burns it is dangerous Cotton is a popular application, used by itself For slight burns it will answer but if they are so extensive that suppuration is to take place, it should not be applied in this way Other remedies that are useful upon the principle of excluding the air, are the oils as sweet oil & lamp oil. Linseed oil mixed with one third part lime water, is especially recommended When suppuration takes place and the cicatrices do not form well, oily application should be laid aside and if there is considerable discharge apply absorbents, as plaister of paris, chalk & chalk & cerate i.e. apply chalk first & cover with cerate. Note from Dr Woodward of Wethersfield extracted from Dr A. Talcotts notes “Apply immediately spts turpentine to the inflamed parts and cerate of limewater & linseed oil equal parts on cotton to the vesications 2nd If pain & irritation ointment of stramonium 3d To prevent fungus Rx white lead a teaspoonful lard 2 tablespnfl. ft. ung. Orgrate or chalk and apply simple cerate over it. I have seen a metastasis at the end of a week to the bowels with diarrhoea & tumefaction or the bronchia with croup Treat with opium & bark Dr S. B. Woodward” N. B. I extracted this principally on account of the definite direction about the difficult treatment required according on the burned part is vesicated or not a point on which the above notes of DR Ives do not seem to be sufficiently precise 181 Should there be a fetid discharge from the burn, it may be remedied by pulverised charcoal. Sometimes the ulcers are very difficult to heal and repeatedly break out afresh A fungus may arise upon the part if so it should be touched with caustic. The eager of the ulcers may be touched with sulph. copper or nit. sil. chalk then applied and the whole covered with cerate. If the burn is on parts liable to unite in healing, as between the fingers and toes, care should be taken to prevent the union. A bad cicatrix is often formed which it is difficult to prevent or cure. Internal Treat When the constitution has received a severe shock and the extremities become cold and the powers of life being to fail, the system must be supported by stimulants & cordials & the excessive irritation relieved by opiates. Laudanum ammonia, spirits, alcohol ether are all good. To a child from 5 to 10 years old 15 drops of laudanum may be given; warm-applications may be made & warm aromatics drinks as ginger tea & mint water administered. Elixir paregoric is one of the best preparations of opium in such cases In a case in which a large quantity of sulphuric acid had been drunk by a boy who immediately afterward, ran to a brook and drank of the water. I merely give mild mucilaginous drinks & the patient being of a strong constitution recovered 182 Croup from p. 138 In what may seem to be the second type of patient may go off suddenly. If he throw his head back in order to enlarge the chest it is a bad sign I have found the treat. by tart. ant. so infallible in the first stage & in general so useful that I have not been tempted to desert it. If I am called rather late and find ext. ant. acting locally upon the stomach, I seldom succeed in curing the patient. Other emetics may be used when the excitability is worm out for [illegible] Calomel is proper in the latter stages, [illegible] the disease is partly broke up by antimony If the first stage is not interrupted [illegible] the child may be playful between the paroxysms and though the pulse is not affected, yet the second will surely come on In the second stage bleeding is to be first resorted to in order to prepare for emetics bleed even to fainting conjoining the warm bath for the same etc. Exciting and irritability [illegible] in this second stage do mischief. I have seen sanguinaria do much mischief. Even after bleeding purges is not advisable for as has been remarked there is a constant tendency in the system to the return of this inflammatory symptom Cal. may be given though if it act by the bowels it will be useless. I have seen bleeding and the vapour bath palliate the symptoms. Scarcely ever will the patient recover 183 Croup In the latter part of the last stage the child throws its head back. This is a dangerous symptom. Now the patient goes into the last or suffocating stage. The patient lies on its back struggles violently for breath countenance livid appears apoplectic and often goes into convulsions and in these convulsions sometimes dies Sometimes in this stage you may hear a flapping of the false membrane. This is sometimes thrown up and great relief is afforded and the friends think that all is over. Soon however in most even of those cases a membrane is formed lower down & the patient ultimately dies In this stage the metallic emetics have in a few cases succeeded The sulph. cupri & the sulph. zinc have each cured Cal. is recommended & may be used The cold both has been recommended It may be tried as a dernier resort. In the second stage after bleeding blisters shd be applied over the whole neck & chest Dr Hosack recommends bleeding from the back of the hand immersed in warm water After bleeding has succeeded in subduing the symptoms cal. & the warm bath shd be used 184 Croup This disease has been divided into acute & chronic but without much propriety Sometimes it continues for some time. I have known one case which continued 3 or 4 weeks In some seasons a different mode o f practice is better. I have known seasons in which cath. & diaph. were the best treatment Although for the first 15 years of my practice I considered nothing more unfortunate than to find the child under the operation of a cathartic. In these cases, it was the form in which the duodenum is also affected in a similar manner Case Wallingford [emet.] failed & cal. & diaph [illegible] Others that season occurred which required the same treatment Bronchotomy has been recommended I have seen it performed but never with success It has sometimes succeeded But in the cases which I saw the membrane form lower down, and the patient die 186 You will see by looking into the throat the tonsils perhaps red & the epiglottis certainly inflamed 187 Angina Laryngia Another form of the croup has been called angina laryngia [illegible] the croup you can see nothing by looking into the throat In this the epiglottis & the [illegible] glottidis are affected From the larynx being affected, the actions & more spasmodic Frequently comes on while eating Case of my child While apparently well was taken while eating with the peculiar croup & respiration of croup & became alarmed & treated This is the form which attacks old people probably Geo. Wash. died of it Case The first time I saw this disease the pat. had had pneumonia & may nearly recover when he went into the cold open air without stockings. I was informed that he was taken with difficult respir. & without seeing him prescribed seneka injurious ultimately refused to swallow anything as the act brought on a spasm I tried bleeding, blisters, vapour & after awhile persuaded him to swallow when I gave him 4 gr. tart. ant. in a cable spoonful of water 188 Angina Laryngea The dis. is brought on by eating And if you examine the throat you will see a redness perhaps upon the tonsils, and will certainly see the epiglottis inflamed Bronchotomy promises more in this form of croup Readily distinguished for the other by difficult deglutition paroxysms being brought on by an attempt to swallow This firm It is not of much consequence to distinguish the forms except that laryngea is more rapid And you must avoid acrids in this form as they irritate the fauces & produce spasmodic action For the spasmodic symptoms give in the latter stages of it asafoetida which also acts upon the secretion tinct. ant. & opium It must be remembered that this disease cannot be cured by bleeding alone. It is too far out of the circulation. But by reducing the system very 189 Croup concluded When croup follows other diseases it is more rapid and dangerous they are very apt to die particularly when following ulcerated sore throat You may treat by emetics blisters metallic emetics etc. but you have not so much strength left in the system to act upon In the latter stage where we wish to throw up the membrane the stomach may lose its excitability to a particular emetic then you are to change the em. I have succeeded in throwing up Upon dissection a membrane is found formed But sometimes it is wanting and in A laryngea then probably is not [time] for a membrane to form Vide p. 211 low and suspending the functions you may change the secretions perhaps 190 191 Scarlet Fever Withering in his first edition separated ulcerated sore throat from scarlet fever. In the second he changed his opinion Where there is much heat and fullness of the pulse I would much prefer a strong dose of cal. followed by antimonials [to] commencing with emetics Or is Dr Rush & the elder DR Barton thought best turpeth mineral Epispastics are to be used with caution & adopted this rule viz to apply them where there is much tumefaction [illegible] & enlargement approaching the quinsy. Scarlet fever after resembling quinsy and is with difficulty distinguished except from the previous affections of the family and neighborhood Mineral acids have been considered specifics Chlorine was much used in this town in [1801] etc. as a fumigator. You may give it internally with advantage A great variety of gargles are used generally stimulating ones are better as those of capsicum (with salt say in cider water) In some cases capsicum does not do well If the patient is too weak to gargle use a syringe 192 Scarlet Fever Chlorate of potash was used with advantage to quiet the stomach. It allayed irritation etc. Ammonia and amm. with camphor & gum arabic In the progress of the disease mineral emetics, as sulphate zinc will be useful to excite the system acting speedily they do not exhaust sul. zinc 5 to 20 grs mosely’s solution was the form most used Sulph. copper 2 to 5 gr. also as an emetic Acetate of copper was formerly kept as a nostrum in some families ½ to 1 t. sp. of sat. sol. of common verdigris 2 to 3 gr. In some cases and seasons cath. are required. I have treated children without a single cath & yet in the same family I have given ant. followed by cal. & worked off by salts and senna If a diarrhoea occurs early it must be attended to white decoction 193 Scarlet Fever Dr With. lays great [illegible] upon diuretics particularly senega giving it throughout the disease. In moderate fevers diuretics eliminate morbid action will Serpentaria may be given freely throughout the disease adding bark alcohol ether or wine Diuretics & diaphoretics Irritable state of the stomach is to be counteracted by irritants by aromatics white decoction etc. etc. a little alcohol upon the fauces voiding a great bulk of liquid Case of a boy in delirium his father was forcing down articles which he was puking up I put into his mouth spoon dipped in brandy 20 or 30 drops his eyes opened immediately said it was good continued it in tspfl doses through the night saved his life Scarlet fever occasionally passed by insensible gradations into quinsy and is of an inflammatory character. No one character will distinguish them No one mode of practice will answer in all cases though if any indiscriminate mode of practice is to be followed that by emetics and stimulants will be best In many cases no evacuations at all are to be used if this you must judge by the symptoms In the same family I have lately treated one or two patients with antimonial and nitre and another who had been worn down by fatigue and watching with feeble pulses vomiting coldness etc. was treated by external heat, brandy in moderate 194 Scarlet Fever quantities, counterirritants spiced tea etc. to stop the vomiting # (One of the best articles in fevers of a low grade is spiced tea or hot spiced wine or brandy. The strength is apt to give out first, and an excitement kept up in the mucous membrane of the stomach will have a beneficial effect) # The first patients in this family I had evacuated freely both by vom. & purging etc. while this patient had no evacuation goodness & was supported throughout the whole progress of the disease After I had seen the disease in 3 or 4 epidemics I thought I had seen the disease in all its forms but I found oftenwards that I met with different forms still Not only different epidemics differ, but different cases during the same epidemic may require widely different treatment In the malignant epidemic of ’94 I was informed by some physicians that they met with cases in which there was increased action though the many cases of the epidemic ran rapidly in the [illegible] gangrenous state In 1803 we generally gave emetics It is said that in the malignant form the eruption is a bad symptom. I do not think so. I think it better for a general eruption to come out the action is less unequal than if a scanty or no eruption appears I hesitated in 1803 much about the application of blisters & I finally found that the rule was a safe and beneficial one to apply them where there was swelling of the tonsils In this epidemic I gave bark, the mineral acids, alcohol, wine, and (for the first time) tinct. canth Tinct. cant. [illegible] zi to pt. give 20 gtts once in 2 hours ½ as much to a child 195 In many cases [illegible] requires to be qualified & corrected by serpentaria or carb. amm. If wine injures the stomach and [illegible] too locally continue carb. amm. which will render it diffusible with white vinegar will have somewhat of an effervescing mixture Use also effervescing mixtures, as soda water, with brandy or ether, or aromatics tincture. It is no objection that you thus combine stimulants and refrigerants, for you thus get diffusible action and obviate unequal excitement. The min. acids may be given in form of punch The sugar will be grateful & useful A diarrhoea is apt to take place in the commencement of the disease. Use white decoction laudanum & injections of starch & laudanum RX starch 3 bal. sp. SS. 30 gtts to 2 t.sp. Pay great attention to cleanliness of the patient Where there is fainting apply ammonia and ether & spirits at the nostrils keep them applied to the nostrils to prevent fainting, I have never known any injury done by over excitement by these articles thus applied Capsicum is used in tropical [illegible] in very strong decoction. Salts and vinegar has been much used as an antiseptic gargle? For the diarrhoea use tonics, bark, contrayerva has been though valuable. Avoid injuring the stomach by distention 196 A variety of garbles (or injections by a small syringe) are used. [illegible] rosemary has been thought a specific & carried hundreds of miles into the country Use others when pat. is disgusted with one # Sulph. cop. ac. cop. nit. sil. ([touched]) apply these with a swab What is called the leathery inflammation is sometimes met with. in which the skin dies at first and afterwards comes off & then a discharge follows. This affection sometimes extends down the throat. In such cases apply blisters to the sternum Touch the part with nit. sil. in such cases. IN one of these the blister on the sternum produced an ulcer which was 3 mo. in healing and in another though the affection with throat was relieved the ulcer for the blister destroyed the little patient # [illegible] oak bark etc. pomegranate combine brandy aromatics etc. It might to be remembered that in the latter stages of ulcerated sore throat where there is an accumulation of [many] a phagedenic ulcer, emetics of sulph. zinc give tone and excite action also when Acetate copper in the latter stages used in an emetic as a tonic or locally applied as a caustic When the stomach fails in the latter stages we give capsicum in pill or strong infusion (2 tab. sp. to the pt makes a strong infusion give to an adult a tablespoonful also acrid oils There seems to be an erythematic infl. of the mucous 197 membrane of the stomach hence acrids are indicated to excite action Bark jacket also it seems to have some effect In the latter stages also a cath. will frequently be beneficial an accumulation of feces may exist given mild cath. as castor oil or perhaps a dose of cal. an emetic also may be needed One thing to be guarded against in young children is the supervention of dropsy In 1803 I had 3 cases all the writers considered the disease as one of weak [illegible] action and requiring tonics bark etc. Not successful Bark does not generally do well when there is unequal action I have known in such cases the brain & nervous system apparently much affected I have given in such cases digitalis and cantharides to produce as new excitement and ally this irritation in the nervous system Case related patient very low from a disease digitalis was given and elaterium being advised was given when the patient died upon the second evacuation In general treat these cases with diuretics a moderate use of cath. narcotics & remedies etc. Digitalis is the best narcotic but be cautious giving it to children In ordinary cases of such dropsy a cath. will remove it and frictions & exercise in the open air. Various articles are popular as ol. [mor] [199] [illegible] ol. gaultheria various irritants etc. and to encourage the attendants to persevere in rubbing you may suffer friction to be made with these mere dry friction though probably just as good does not seem to them like giving medicine Various astringents may be 200 Hydrocephalus The management of the pat. is equally important with the medication avoiding in proper diet alternatives of temperature, and all debilitating irritating and exciting agents all the exciting causes of disaster. Sometimes a patient may (after a fall perhaps) continue one two or 3 years not entirely [illegible] and yet not quite sick and finally die of eff. of the brain Sometimes in strumous habits canth. internally may be advantageous Blisters translate action The applications of remedies to the Schneiderian has been thoroughly treated by Dr Malachi [Foot] in the N.Y. Rep. about 20 years ago. The subject has not bee sufficiently attended to Give in the way turpenth wine (mixed with liquorice) verat. vir. apreyn. [illegible] myrica cerifera etc. If a discharge can be excited relief is afforded Salivation can rarely be produced in children In some cases where there is paralysis the acrids and some of the narcotics as strychnos Blisters are applied by some to extreme parts of the body I sometimes change the place of the blister to the back of the neck etc. But the back of 201 ears is more efficacious. It seems to have a grater affect upon the constitution to excite a discharge from this part If the symptoms indicate bleeding bleed leech also. If there is much infl. about the mouth scarify the gums as a depleting measure “In grade of action the fever of hydroceph may vary from high entonic inflammation or phrenitis to low strumous fever. If the action is too high or too low counterirritation will fall in with the morbid action We must first bring it to the “blistering point” (Rush) “Blisters to the head are thought by some to be dangerous and the ears or neck preferred” “In irritable cases and scrofulous habits, strong cathartics are hurtful. Give blue pill especially when the bowels are primarily affected. But in entonic phrenetic fever, use the drastic cath. & tart. ant. ut supra after depletion” “Scrophulous predisposed mesenteria glands generally affected the fever analogous to hectic never entonic pulse soft, frequent, quick I have tinct. cantharides with advantage in this variety” [204] Volvulus continued from p. 89:a:1/2 “Cases I was called to a child 2 years old which had symptoms of irritation and was obstinately constipated It had been carried on the belly upon the shoulders of another person Gave a cathartic Ordered an injection but the attendant said it would not [illegible] The cathartic was thrown up patient died Upon examination after death no color could be found. In the upper [illegible] rectum there was a tumor which seemed of solid flesh as large as the doubled fist inflamed. The color had been completely removed from its place” “I was called to another family where the children had died when 5 or 6 months old as was supposed of an affection of the brain. This child appeared well when born but was very costive etc. Upon p.m. [illegible] 2 inches of the small intestine were found contracted to the size of a goose quill the coats were thickened & the course the cavity must have been extremely small This contraction undoubtedly existed at birth. This contracted part was received into the part below it, and no [illegible] could have availed” from p. 99 ½ “In another family they had lost all their children at about such an age. They supposed the disease to be hydrocephalus. The older physicians called it so. I told them I could not tell what the disease was but it was not hydrocephalus I had then seen no case of volvulus. There were strong 205 marks of irritation the face was pale and much distress was depicted with countenance the head was rolled back and hands tossed violently. There was vomiting and tenesmus and a discharge of mucus streaked with blood Cathartics had been given under the impression that the disease was an affection of the head The cathartics aggravated the disease which ran a rapid course and the child died. The small intestine was found received into itself and its cavity obliterated. This obliteration of the cavity would not of itself cause death; for a patient may continue several days with perfect torpor of the bowel. It is the irritation as in cholera morbus which is the immediate cause of death which [illegible] death usually occurs within 24 or 36 hours” “Called to a child one year old constant vomiting stool, mucus streaked with blood Directed mucilaginous injections & fomentations combined with opium Gave opium freely internally 10-15 minims to allay vomiting. The symptoms subsided gradually & in 3 or 4 days the feces passed off without any cathartic” “Was called to an Academical student had given cathartics and they did no good. Called in older physicians. They were in doubt respecting the case and advised not to do any thing as we might do hurt. As I was sitting by his side I heard a motion in his bowels. I noticed that it passed down to a certain point and then stopped. Upon examination I could distinctly feel the involution. I tried injections and some [illegible] of them would stay. Ordered a spermacetic candle with opium upon its extremity to be passed up the rectum and allowed to remain. It was s 206 passed in to the length of 10 inches. The opium allayed irritation and the application by repetition replaced the part & the patient recovered another case cured by a bougie” “Opium by taking off the spasm and restoring the natural function of the bowels may be said to act as a cathartic just as in spasmodic colic” From p. 56 “I have given when I could obtain it, the [resin] of Mandrake podophyllum peltatum It operates kindly, and more certainly than any other article. If the western gentlemen who have so much mandrake and whiskey, would furnish a supply. I think it [will] supersede every other article” “If there is torpor & a stuffing or infarction of the bowels we must use injections to assist cathartics repeating them every 2 or 3 hours. If other cathartics do not operate give castor oil which will promote their operation” “The particular kind of injection is not important and may be left to parents Thoroughwort, camomile, mayweed catnip, dandelion, weak soap suds salt & water a tablespoonful to ½ pint water 207 Continued from p. 57 “The stools resemble meconium. In the progress of the disease they exhibit small pieces of a membrane of a dark green colours, about the size of the petals of peach blossoms floating in a dark green fluid. The membrane of coagulable lymph, resembles that formed in angina trachealis and sometimes as in that disease it is formed in such quantities as to cause obstructions Still in this case it may not destroy life the action of this part not being so immediately essential to life. Stools of this kind sometimes attend the bilious colic of adults. They are an indication that farther evacuation is needed Continue the calomel or combine it with magnesia or soluble tartar, or phosphate of soda or other neutral salts 208 Infantile remittent continued from p. 60 “Cases A child had violent fever gave calomel & cathartics warm bath symptoms abated. In 2 or 3 weeks the regular symptoms of hydrocephalus appeared; & the patient seised in the greatest danger. In a short time these symptoms were relieved by a violent and dangerous attack of thrush The patient was very much exhausted lay several days very low gradually emerged and after a long course recovered. “Case of a small little boy 5 or 6 years of age After 5 or 6 days head affected & became maniacal very irritable and cross swore profanely would bite and strike all who came near him. If any thing was attempted to be administered he would shut his mouth. If his mouth was pried open he would close his throat with his tongue Advised his parents not to trouble him nor notice him to pass by him with drink roasted apples etc. but not to offer him any thing. The first day to he took nothing second day took roasted apples etc. readily but ate too much mania returned, but soon went off & patient recovered” “In one case the pat. took nothing for a length of time. Recovered by use of [even ato] & external applications as aloetic plaisters to the bowels etc.” Scrofula continued from p. 163. “Scrofulous swellings are very difficult to excite to suppuration I have however then poulticed without effect for 2 or 4 months Of late I have disused poultices & have applied blisters as soon as may be to excite invigorate the absorbents and act as discutients. They do not disturb the system. If there is suppuration the relaxed state requires stimulating applications lunar caustic vegetable astringents etc.” “Case of a young act 18 with bad cough swelled neck scrofulous temperament Gave laxatives blue pill afterwards rub & spec. Then gave decoction of [cistus] [canadensis] for several weeks and pat. recovered “ A physician (Smith) on Long Island (from an old recipe) has acquired reputation by the use of cistus canadensis combined with uva ursi at the same time enjoining a strict & spare diet as in dyspepsia” “I have given with cist. canat. 1/8 gr. corr. sub. & also decoct. scroph. maril. which is thought by the vulgar to be a specific It has been sold as a nostrum to facilitate parturition called nerve root.) I think it useful in scrofula” “I have known the comptonia [illegible] folia given internally. It is tonic & has balsamic rpoperties” “The remedies particularly indicated are tonics & deobstruents such as will not produce congestion such as uva ursi cistus scrophuloria contrayerva agrimonia (entire plant or root angostura etc.” Sea bathing is recommended, but if the lungs are affected, it will not be advantageous. A sea voyage to the eastward has been of service the constant motion of the vessel stimulating all the vital organs to healthy action The change of air is beneficial & at a distance from the shore there is no danger of taking cold In chronic complaints attended with a want of vital energy I direct a voyage to the east rather than to the south Croup continued from p. 189 “Vapour bath Inhalation of warm water in a [pour] blow a current of air through hot water upon the pate & by means of a coffee pot with two spouts” “Tobacco or snuff applied to the patient” “Croup is an epidemic disease & of course it will vary at the different periods of its appearance We must take into account the prevailing diathesis I have described the disease as it has usually occurred in my practice” “The proxim. cause of the dis. is a peculiar morbid action translated to the traches for the disease arises from general causes acting on the system. In catarrh diseased action is seated primarily with mucous membrane. The exciting causes of croup act on the surface and with different diathesis the same crises might produce pneumonia, dysentery enteritis or cephalitis “Disease determines to the weaker part as the rod attracts lightning” Rush Water & snow cold damp air a [illegible] & low situation sudden changes as when the wind blows from Canada or the gulf stream are the exciting causes “In the treatment sanguinaria, if given early in strong decoction very freely, so that enough of it shall be given & still it vomits or relieves the symptoms, in very efficient practice adopted by Drs Jared Potter & Kirtland “But if inflammation has taken place & the second stage has arrived seneca and sanguinaria are both too stimulating and I have seen them do hurt sanguinaria is less stimulating than seneka For p. 137 “Some authors state that the disease is entirely inflammatory not regarding the forming stage. If the forming stage is wanting we must rely solely on the antiphlogistic treatment” “This disease has a direct tender eye to death The physician must take it out of the hands of nature” “When croup supervenes upon catarrh as it frequently does of late year the mucous secretion and expectoration usually cease suddenly “When croup follows diseases that prostrate the system powerfully as angina maligna, there is little chance for recovery. The sympathies of the system are broken down and Archimedes can find no fulcrum for his lever” “I used tart. ant. at the commencement of my practice and succeeded with it as well as I could wish I therefore contained it, but only in the early stages & to produce a powerful orgasm. If it acts upon the stomach only it aggravates the disease Other practitioners rely upon different articles & probably with equal success bearing in mind however that a powerful impression must be made Decoct. sang. to prostration & vomiting seneca or lobelia inflam with the same view” “Sulph. copper & zinc & acetate copper useful to assist in the latter stages or when other emetics are worn our. So also hives syrup which is much used at the south.” “For six or 8 years past croup has been occasionally different from the pure inflammatory. It affects the lungs and duodenum& calomel and cathartics are the remedies to overcome this form. The cough is more frequent and loose the paroxysms less distinct there is pain in the epigastrium vomiting & a membrane is formed in the duodenum which passes off. I have called it angina duodenitis. The same year ulcerated sore throat came on with it the slough leathery & like a burn it seems to be intermediate between A. tonsillaris & A. maligna The application of lunar caustic by a pencil or brush would prevent croup Blisters to the throat & chin were useful yet a blister would produce the same action as existed in the throat, forming an ulcer very difficult to heal Slough ¼ in. deep 3 mo. in healing. In one case the blister cured the croup and the ulcer killed the patient It is desirable to translate action to parts less essential to life. Cal. & carth. would translate it to the duodenum Emetics & powerful treatment do hurt here. The vapour bark is good. “Croup sometimes recurs several nights in succession A. Laryngea is more apt to do so” “When crop assumes a chronic form emetics irritate inhalation of vapour blisters opium diaphoretics & expectorants” “In chronic croup the inflammation in erythematic and not membranific. The vapour bark often does wonders Tartrate of sanguinaria in ¼ gr. doses Tinct. hyoscyamus gtts x N.B. Dr Woodwd treat of subacute ([S?bertonic]) & typhoid croup the latter contraindicating tart. em. & requiring sanguin. turp. mer. calom. etc. & sometimes capsicum, ammonia & even perhaps wine & alcohol. “One of the most extraordinary examples on record however of the effect of disease in developing of perceiving a certain class of relations is that of [Zerab] Colburn His history is well known When quite a child in his sixth year, without any previous instruction, he could by mere intuition perceive the relations of numbers with so much readiness and precision, as to solve almost without reflection questions in arithmetic which would require a long calculation to enable others to answer. How he obtained this result he could not tell. The answer seemed to present itself to his mind with the same readiness and conviction of its truth, that the proposition tow and two make four does to us. These facts I saw are well known, but it is not so well known, that this power was the effect of disease. That such was the case I have very little doubt This was the opinion of a very distinguished physician who saw him at the time, and who ascertained that he was then affected with a peculiar nervous disease the same (chorea) which Jane had a few years since. In conversing with Mr Colburn about a year ago I asked him if he retained the power of calculation which he possessed in his childhood. He said no, and attributed the loss to the want of its exercise. But why should exercise sustain a faculty in existence which was spontaneously developed?” “Account of Jane C. Rider the Springfield somnambulist; by S W Belden MD. Springfield 1834” p. 108 “The discovery of Zerah’s power of calculation was purely accidental Zerah not having yet completed his sixth year was overheard by his father, as he repeated to himself in his play, parts of the multiplication table. The father surprised proceeded to examine him & [found] etc. 1 Diseases of children [B illegible 31] Proposed plan name – history symptoms & causes [Regar] plan of treatment minutely described Other modes of treatment Miscellaneous remedies N.B. Collect all his remarks on art of practising medicine Contents page Introduction Tumour of the head from difficult parturition 5 Cutting the frenum linguae 5 Congenital hydrocele 5 Management of children – as to Particular appetites – Preventive medicine 5 General nature of the diseases of children 6 General operation of remedies in children Diseases within the month Retention of the meconium 8 Jaundice 11 Acidity, Flatulence, Hiccough etc. 12 mothers milk & cows milk 12 Costiveness & its consequences 12:a Vomiting 12:d Diarrhoea 12:f Prolapsus ani 12:l. Aphthae 13 Eruptions in general 19 Strophilus interlinctus or Red gum 19 Strophilus candidus 21 Crusta Sactea 22 Eruptions of Dentition 24 Eruption resembling the itch 24 Venereal Eruptions 25 Infantile Erysipelas (Rose rash) 27 Sore ears (Intertrigo) 30 Tinea capitis [???phlicus]- [illegible] [illegible] on [illegible] [1821-2] 32 Dentition 34 Cholera Infantum 40 Infantile Remittent 55 Mesenteric Fever 61 Tympanitis 66 Worms 69 Volvulus 86 Nervous Rheumatism Infantile [remedy] 89:a. Convulsions 90 Epilepsy 96 Catalepsy 99 Chorea 100 Ulcerated mouth 103:a. Gangrene of the mouth 104 Parotitis or mumps 112 Tonsillitis or Quinsy 115 Rosalia or Scarlet fever 120 Croup or Bronchitis 132 Laryngitis 139 Epidemic catarrh resembling croup 141 Whooping cough or Pertussis 144 Rickets 158 Scrofula 162 Mesenteric fever Hydrocephalus 164 Chilblains 176 Painful aff. from cold without discoloration 177 Burns 177 The cause either is to be found in [???uctural] [illegible] for the [illegible] This will [illegible] men to trust their lives to unknown men, or to fictitious names in the newspapers, where they would not trust property even to a small amount # Formerly prescription of an experienced physician very often set aside for that of the nurse or a negro woman 1 Diseases of children 1 In this part of our course I direct your attention to the history of man in relation to his habits, diseases, & their remedies in his infant state That this subject has occupied the attention of the learned less than any other branch of the medical profession, is universally acknowledged 2 – It is unnecessary for me to enforce the importance of the subject, by any remarks which might be made concerning the evil to society from a neglect of a part of the practice in which the community is so deeply interested 3 – I need but advert to the evils which must result from the practice of committing the management of the diseases of infants to a class in society which is the lowest in point of intelligence 6* [the opinion of the nurse is sometimes taken in opposition to that of the physician – On this subject the world seems to desert its principles of reasoning on other subjects. If a point of law is to be decided men will not trust to a petty of the court, in preference to that of an experienced If a text of scripture is to be explained, men apply to a learned divine in preference to the mere servant of the church & on the subject of wearing apparel it prefers the opinion of the master to that of the apprentice.] 4 – That this subject has occupied the attention of the learned less than any other branch of our profession is universally acknowledged. (The French & Germans however, have neglected it less than the English; and the American physicians have been in the habit of paying more attention to diseases of children than the Europeans) 8 Great attention has been paid to diseases of children within the last 30 or 40 years It has been most neglected in Europe, but less by the French & Germans than by the English 17 European practice differs from ours – but less so at present than formerly because the constitution of our countrymen are coming to resemble those of Europeans 12 It is also the case that European diseases differ from ours on account Disease, here is [illegible] more violent owing probably to the greater of climate etc. Angina [Trachealis] is much milder with them & requires much milder treatment # vicissitudes of the weather 2 5 - The causes which have excluded physicians from the treatment of [infantile] diseases infants, having ceased to exist the subject is now receiving the attention which its importance demands 6 – These causes may be enumerated in few words – viz. the exclusion of the faculty from the practice of midwifery – from the difficulty of obtaining correct ideas upon the subject from its obscurity – the prejudices of the public on this subject – attributing as they do intuitive skill to nurses and matrons * vid. page [illegible] & perhaps also the indifference of the profession 7 – At the present period, however, the enlightened physician watches the mother during the whole period of gestation, receives the child upon its first introduction to the light, & prescribes for its diseases from infancy to old age 9 – As knowledge however must on this subject, as on every other, be progressive, it follows that this part of the profession having but recently received the attention of physicians, has not attained the perfection of the other branches 10 – American physicians need American treatises on this as on other medical subjectds 13 – European practice, as exhibited in their works, is too slow and mild to meet and overcome the morbid excitement of acute diseases in our climate. [Chronic diseases may be treated They practice no deceit 3 with mild remedies, but acute diseases are made worse by remedies if those remedies are not sufficient to overcome the disease The action of the remedy falls in with the diseased action and aggravates all the symptoms if it is not powerful enough to overcome the diseased action IN such cases disease is to be taken out of the hands of nature. The powerful [enemy] is not to be irritated unless there is a prospect of overcoming him] 14 – The difficulty of acquiring a knowledge of the seat of the diseases of children, on account of their being unable to communicate their sensations by language, has been made an excuse by some physicians for neglecting the subject of infantile diseases We may remark however that the difficulty of attaining a correct knowledge of a subject, cannot be given as a reason why it should not be committed to men of intellect & science 15 – Though children cannot communicate their sensations by language, yet the other symptoms by which we determine the seat of their diseases are more uniform in their appearance & more certain in their indications than those of adults 16 Children are under no restraint from feeling fear, [delicacy] or from false modesty In the infant, the mind does not react upon the stomach & destroy its function When Dr Harris published his essay on the acute diseases of children Sydenham said to him “you are the first man I ever envied and it is my firm belief that your little book will be more useful to mankind than # Adult patients also will often deny the existence of dangerous symptoms; for fear they shall be considered as very sick The subject has not yet been thoroughly investigated. No regular course on it has been [illegible] until quite recently in [illegible] of the European schools. I recollect the embarrassment under which I laboured under at the commencement of my practice Cases frequently occurred which were not described in any of the books [&] I was obliged to acquire all my knowledge on the subject from older physicians or from experience. My students have often expressed to me the satisfaction they experience from an examination of my notes and they have often quieted the anxieties of parents by reading extracts from them # In my embarrassment upon being first called to a sick child though familiar with the treatment of adults & having attended the first schools in the country I found my information & in books as to [illegible] nature or treatment and was obliged to have recourse to the older physicians 29 [Dewers] is popular addressed to mothers, very prolix & not intended for a text book but perhaps able [work] & is the 30 [illegible] # Parents think a young physician will do well enough for a young children and are much more apt to call one in for such patients 4 mind does not react upon the stomach & destroy its function We are at no loss how much to attribute to disease & how much to [illegible] # 17 – Still with all these advantages & notwithstanding the importance of the subject it has been neglected & has received less attention than any other branch 18 – When Dr Harris published his essay on the acute diseases of children Sydenham said to him, you are the first man I ever envied, and it is my firm belief that your little book will be more useful to mankind all I have written” This opinion was not founded upon the merits of the book but upon the fact that the attention of physicians would be drawn to this part of their profession, not the least useful though the most neglected 25 Authors on this subject & their merits 26 Underwood Still the department has received less attention than any other branches of our profession 27 Dr Rush in his works, has many remarks 28 Periodicals contain more or less upon the subject 21 – No courses in any of the schools 19 – Some physicians of the first respectability have acknowledged their ignorance & given up to nurses 20 – I recollect the embarrassment I suffered upon this subject # It is a common complaint 22 Since I have lectured upon this subject, our students at parting have expressed their satisfaction. 23 Young physicians are first called to children because the older ones neglect them # hence its importance to them 24 Parents however seem, as a matter of fact, to prefer a young physician, for a young patient! # 34 – I shall first remark upon a few surgical cases which occur to the young physician soon after the birth of the child [illegible] cutting the frenum. I have never seen a case in which this operation was necessary. It is very common for nurses to insist that children are tongue tied. Dr [Eneas Munser] was called in such circumstances he remonstrated the nurse was instant until finally he drew the back of a knife across the frenum & the child he told [illegible] [illegible] hurting and this with this [result] was relieved to the great satisfaction of the nurse. If there is a false frenum it may be divided.” this [illegible] [frenum] is never so short as to confine the tongue & cutting it is a dangerous operation # They will tell you that this particular appetite is indicated by the natural crying of the child The mother will set herself to recollect some former longing of her own [illegible] 6 Hydrocele Young physicians are often called on to prescribe for congenital hydrocele in young children The complaint is apt to excite alarm but neither troublesome nor dangerous. It is readily distinguished from [illegible] by its transparency, insensibility, & not yielding to pressure. In the course of my practice I have had to operate in but one case in children. Dr [Dewers] recommends pouring considerable quantities of cold water on the part. I myself have frequently cured it by washing the part with cold water in the morning and applying camphorated spts in the course of the day. You [illegible] direct the application of spirt & water, camphorated spirits, [muria??] of ammonia, [opium], spirits of nitre, in short every discutient Or you may direct astringent lotion, as a strong decoction of maple bark, spriaea Fomentosa Geranum, Rhei etc. Case in which I had to operate year old probably neglected 2 or 3 inches long about as large as a small egg. Operate without a cannula - with a lancet & catheter & injecting syringe – water 1/6 or 1/8 port wine – children more irritable - vomiting 5 Tumor on the head 35 Children are sometimes born with a tumour on the head occasioned by difficult labour This may be distinguished from a tumor caused by a deficiency in the bones of the cranium, by a uniform hardness. “We may apply mur. amm. or spt & water” 36 – Cutting the Frenum 37. Hydrocele 31 Management Appetites 32 A prejudice prevails in some classes of society with respect to a point in the management of children Some children are thought to be born with a strong appetite for some particular kind of food, which was possessed by the mother previous to the birth of the child & inherited from her. It is thought that the child will [pine] & ultimately die, if this [illegible] appetite be not gratified # It is probable that a belief in this doctrine has caused many children to be killed by the administration of improper food A fact of this kind occurred in Humphreysville, which nearly proved fatal to the child. Vide next page Preventive medicine 33 As a general rule medicine is not to be given to children in health for fear they should be sick. Some are nursed to death, while some die for want of nursing. Some are fed to death while others are starved Some are physicked to death while others die for want of medication injection immediately with [draw] healed [illegible] with swelling The child cried much # - a council of females was called who set themselves to make out what the child needed Finally the mince pie was concluded to be the article the child sucked down the inside & the report was that this effected a cure & saved the life of the infant. Prof. I inquired of the attending physician who informed him that the child was indeed alive and well at present but that it was made very 8ll by the mince pie & came near losing its life. The crying of the child in this case was probably nothing more than a trifling increase of the ordinary crying of very young infants, which is a natural and wholesome exercise # The al. can is large in proportion to the [illegible] of the whole system # The above is a good example of the various prejudices which have prevailed among [nurses] respecting the management of children. Owing to the influence of enlightened physicians these are no disappearing. (examples to be given) 6 38 – Diseases requiring medical treatment General considerations 39 – In investigating the causes and seat of the diseases in infants the mucous membranes claim particular attention 40 The action of this membrane is greater in the infant than in the adult constitution Its secretions are often morbidly increased & are sometimes diminished. It is subject to spasmodic action and to inflammation [illegible] with [illegible] or decomposed with effusion of coagulable lymph. “It is subject to turpidity & to spasmodic action which by sympathy extend to the whole system 41 The liver is much larger in proportion to the body the infants than in adults “& its secretions are much of [illegible] as to quality & quantity than in adults” 42 The secretions are much concerned in their diseases. They are changed as to quantity and quality # Prescott child no ducts lived 3 or 4 months and was excessively emaciated – there was no bile in the stools There was no [previous] duct for the gall bladder into the disorder # There is greater susceptibility to action & tendency to conversion # Just as emetics are given to a stomach [complaint] from excessive quantity of food 7 42 The nervous system of infants is more easily excited, and more affected by the various causes of irritation such as dentition worms acrid substances in the first primae via passages etc. 43 – The blood vessels are more rarely the seat o f disease in infants than in adults – particularly, primarily so much as irritative [acid] if they were affected the action is not [illegible] 44 – Consequently their fevers are fevers of irritation, rarely enteric or those of inflammation 45 Operation of medicines Children bear evacuation better than adults witness the long continued diarrhoea without much debility following, or the salivation for mouths during dentition without a waste of vital energy In operating upon the abdominal viscera it should be [illegible] it is not for the purpose of mere evacuation, it is to produce an excitement for the purpose of overcoming a morbid excitement also to produce healthy excitement a case of torpor # The milder purgatives should be used, the drastic being irritative. Emetics Bleeding Do not bear narcotics vide p. 11 2 – In general the evacuation of the meconium should be effected by the [colostrium] or first milk of the mother which has a laxative property # The child should be put to the breast within 2 or 3 hours from birth # unless [illegible] Instead of suffering the nurse to feed the child for the first 2 or 3 days the breast should soon be presented for if the child feeds it is in danger of losing the instinct to suck If the [colostrium] does not bring away the meconium we may begin with soda as mentioned below or with cold sweetened water Some give a little cold water at first vide [infra] 5 – In strong children cold bathing may be employed with advantage, but the bath should be made tepid for weak ones & gradually used colder as the child can bear it # “If from the exhaustion of parturition the mother be unable to suckle let the nurse commence feeding at the end of 3 hours” vide infra Give a grain of carborate of soda in a teaspoonful of water until iii qts [have] given # The meconium is frequently evacuated during parturition. After birth also the al. canal is set in notion by the crying and mother of the child and the stimulus of the air upon it vide p. 10 skin. # Colostrium is of a yellowish colour probably contains bile & is cathartic # It was formerly supposed that the child should not suck at first. The consequence often was that the child lost the interest to suck 8 Retention of Meconium 1 – The first diseases of infants which claim the attention of the physician are those which arise from retention of the meconium. The meconium is a matter always existing in the bowels at birth & having a dark green colour when evacuated. It resembles tea but is more mucilaginous # It will ordinarily be sufficient to give a little molasses and water to the child until it receives the [illegible] or first milk from the mother which has a laxative quality 6 – If it is suffered to remain a train of diseases may follow. In the diseases which occur within the first moth after birth the retention of the meconium is always to be suspected as the cause 7 – The diseases caused by retention of the meconium are Severe paroxysms of pain in the bowels indicated by crying & writhing – Tumefaction of the bowels. Convulsions. Epileptic fits. Trismus nascertium or Locked Jaw This last disease is very common in some of the West Indian islands, but I have never seen it in this place 8 – Whatever disease may arise from retention of the meconium the principal indication will be to remove the irritation by evacuating the bowels. This is effected by cathartics. A teaspoonful of castor oil is generally sufficient. If [illegible] necessary 1st indic to remove meconium 2nd obviate effects # IT will be sufficient to pour on boiling water instead of boiling the materials in the water The strength however is of little consequence Sometimes the most powerful remedies are to be used beginning with mild. These used full doses of calomel, scammony 2 to 4 yrs – [illegible] assisted by injection, & warm bath until the bowels were moved Wait how long for the operation of each? # By emollient injection, irritation is allayed, and if the lower part of the bowels is excited the rest will be Dose 2 to 6 pills each pill containing 1 gr. of (calomel) # Chalk & calomel is a substitute for blue pill – perhaps the chalk qualifies the cal & at least it corrects acidity Antimony should scarcely ever given to children within the mouth # A great part of the calomel has no effect [illegible] it does not come in contact with the coats covered with mucus In cases where there was great quantities of [mucus] I have given full doses of cal. 9 the dose may be repeated every 4th or 5 hours until half an ounce has been given 8 – If the oil is rejected from the stomach Senna & Manna may be given – zi of the former to zss of the latter boiled in gill of water # & administered freely until the bowels are moved once in ¼ or ½ hour “ Rx Sennae zi [illegible] ferv. 1 gill 1 or 2 teaspf every ½ hour” 9 – The operation of the cathartic should be assisted by emollient injection # 10 – Fomentations to the bowels will assist the operation of cathartics & if spasms exist, will always be needed for their relief 11 Cathartics of various kinds 12 The best cathartic which I have used for infants within the first month after birth is the blue pill (or [mellated] pill It rarely offends the stomach and never produces griping By it the action of the liver & the secretions from the mucous membrane of the intestines are excited more than by any other cathartic except perhaps calomel. In my practice I have never known an infant salivated by it. # 13 In severe cases where the blue pill is insufficient we must have recourse to calomel, which may be given in doses of from two to 10 grains. It is often necessary to give as large doses of calomel to children as to adults owing to the great quantity of mucus in the intestines by which they are defended from its action. # The meconium scammony or jalap as a laxative & had them operate mildly If the cots were [naked] [illegible] a dose would prove fatal for irritation # This is a mild cathartic and supposed to act chemically. # “Evaporate the [illegible] over the fire stirring it until thick then add chalk till it is of a consistence suitable for pilling Each pill may contain 1 or 2 gr. of Dose from 2 to 5 gr. Or it may be dissolved in herb Fish, gall has been recommended [illegible] gall Rattlesnake has been thought to have specific properties especially in fevers. This article is bitter, tonic [illegible], laxative, & [illegible] Continued from page 8 “The infant may be put to the breast in one or tow hours from birth This course will produce permanent contraction of the [uterus] & tend to stop [hemorrhage] & prevent milk fever” When an infant is first born it is well to wet its mouth with half a teaspoonful of coldwater and give it nothing else until it is applied to the breat 10 while retained will likewise prevent the operation of the remedy by involving it in its viscid substance 14 Chalk & calomel may be used in doses of 1 gr. cal. to 4 or 5 chalk repeated once in 2 or 3 hours 15 Other cathartics which may be used are or as recommended by Dewers 1 gr. carb. sod. to a teaspoonful of water repeated every “it operates” 15 minutes until 10 gr have been given. # Decoction of the flowers of the dandelion & the mullein Senna 2 dr. to with 4 dr. of aromatic herbs or seeds The bile of animals (ox gall) is a good cathartic Perhaps we may consider it as acting as a substitute for the childs own bile. It may be given in [catnap] tea milk etc. # 16 An injection of bitter or 16 aromatic herbs will allways assist the operation of whatever cathartic you use & in mild cases frequently will be sufficient of themselves – superceding the necessity of giving anything by the mouth Continued from p. 8 The stimulus of sound upon the child, crying, irritation of the air upon the skin, and especially muscular motion, excites the peristaltic motion of the child. The influence of muscular motion upon the peristaltic action of the bowels, is considerable, as is seen in horses while travelling, the costiveness of sedentary persons etc. “The warm bath at the temperature of 98 or 100 assists the operation of cathartics renders their action more mild equalises the action of the system and nervous irritation It is especially useful when convulsions are present and may be used at any period except in cases of extreme exhaustion” # It is the most powerful antispasmodic for children [have] acting upon the extremities of so many nerves Jaundice “Jaundice sometimes appears at birth indicated by the yellow colour of the countenance and arising from obstruction of the liver etc. Such cases are generally incurable. The first remedies are the mild deobstructant plant, small doses of calomel etc.” 11 When convulsions are present the warm bath should be used to assist the operation of whatever cathartic is used, to render the operation mor mild, to equalise excitement and to remove irritation. This remedy may be safely used at any period after birth # After the cause which excited the convulsions has been removed, if the morbid irritation of the nerves continues, the bath will again be serviceable 18 Antispasmodics may likewise be used such as valerian, aqua ammoniae, elix. asth. artificial musk infusions of catnip etc. We may use aqua amm. 3 or 4 drops or carb. amm 3 or 4 gr. or asafoetida a teaspoonful of the tinct. in milk & water, or camphor by enema Be [cautious] of giving narcotics to children Some are more susceptible than others. And some children are accustomed to [them] from birth. Case of a mother who had inured a child of 3 m. to bear 30 dr. of SS. I proposed to give paregoric, beginning with 8 or 10 drops, and found that the child had often taken with impunity 31 dr. of SS. to produce sleep 4 – “Child bed women are generally to be treated with mild diet for the first week after delivery, unless their strength has been much reduced by parturition, when they may take port wine in moderate doses” # “If light stools indicate a deficiency of bile the administration of oxgall will be found very serviceable vide [illegible] If acidity is produced, add limewater, If diarrhoea is produced, use arrow root instead of the water, or any other [fecula] Children are apt to receive too much food; hence cow’s milk should be diluted with water. Milk may sometimes coagulate in the stomach of children, in large quantities and occasion much uneasiness Meat should not be given under 6 mo. unless in particular cases which are exceptions to the general rule, where milk disagrees or perhaps in the case of some scrofulous children 12 Acidity Flatulence Hiccough 1 – Very young children are often troubled with acidity, flatulence & hiccough These affections may be removed by a free use of magnesia, lime water, or aqua ammoniae 2 – It will not always be sufficient safe? to administer these articles to the child alone. The mother or nurse must often take them likewise 3 – Sometimes the mothers milk disagrees with the child. This will be known by the constant disorder of the bowels of the child. by the evacuation and pain suffering after nursing both child and [illegible] mother may seem to suffer without a cause The stools may be slimy# The child may cry obstinately 5 – If the mother’s milk continues to disagree we may use cow’s milk diluted with one third or one half water & “sweetened” or with arrow root mixed first with a table spoonful of cold & then with one of hot water, in order to make a homogeneous mixture 6 – Children fed on cow’s milk are more apt to be costive. To prevent this give a little magnesia, decoct. of dandelion etc. Peach tree blossoms are much used, but are too violent in their operation The injection will start the machine again The injection may be made of Eupatorium, catnep, elderflowers mallows etc. etc. Apply first whatever can be first prepared counterirritants for instance. Spirit or mustard to the fat ammonia etc. ammonia to the mouth and nostrils etc. endeavouring to rouse the patient 4 – [A young physician should be careful to know what to do in sudden cases (much depends on a favorable impression at first) Neighbors and friends usually assemble around a child and the expect the physician will be able to prescribe at the moment. In such cases set some of the bystanders to preparing a warm or tepid bath – no matter if eventually if it should not be used. Set others to preparing some other thing and so on. Thus while the attendants are all employed he will be able to devise some course to pursue] I recollect an old physician in this situation who was pressed what to do & replied “stop let us think about it” 12:a. Costiveness & its consequences 1 – Physicians are frequently called upon to prescribe for infants who are in health except that they are costive Children fed from a spoon or bottle are mor to be thus affected than those who are nourished from the breast. If costiveness is produced by improper quantity or quality of the food as is sometimes the case, the diet must be changed 2 – Costiveness if not attended to in time produces flatulence, watchfulness, startings, hiccough, diarrhoea vomiting & convulsions 3 – A physician is frequently called to children I fits, who have been apparently well until the convulsions come on The safest and most efficacious prescription that can be made, is an injection & indeed is all the treatment that most cases will require. Let a warm bath be immediately prepared & the patient put in it if the enema does not relieve. While the convulsions continue the mouth is closed & we can operate on the system mainly by the rectum & the skin 5 Be careful to make your directions for administering an enema very definite, unless you know that the family are familiar with injections Case of a mason’s man hands & knees shooting somewhat off fright rolling over murder The enema may consist of simple warm water, or milk & water, or of tea of thoroughwort or catnep etc. a table spoonful of salt may be added finally castor or other oils may be thrown up in extreme cases the rectum has been filled with lard The water for the tepid 12:b. bath should be about blood warm. Be careful to bathe the child, & not merely to scatter or sprinkle water on it. The length of time during which the child may be kept in the bath may be from 5 to 20 min. While the patient is in the bath if it is sufficiently relieved to be capable of swallowing give a dose of calomel for a child of 6 months 6, 8 or even 10 gr. If improper food is the cause 20 gr. are not dangerous, for infants will bear full doses of cathartics though very small ones of narcotics In bad cases of convulsions the means to which we have it in our power to resort, are external irritants such as garlic draughts to the feet, injections of [nervines] the most powerful of which will be a teaspoonful of tinct. camphor thrown up in a gill of milk & water & the warm bath until we can administer articles by the mouth “If the child be feeble & exhausted upon coming out of the bath give cordials or tonics” Any quantity of food in the stomach & bowels which is not congenial, interrupts the process of digestion & the peristaltic motion functions whose importance is second on ly to that of respiration. When these functions are interrupted the muscles are brought into convulsive action to relieve the system Be particular in your enquiries about food for those who have the care of children are very careless and children will swallow whatever is put into the mouth. I recollect being called to see a very strange worm which a child had voided. The imagination of the attending physician & parent were excited. To me whose imagination was cooler the worm appeared to be a piece of bark I enquired if the child had had no slippery elm bark & found that it had been chewing some. Then the supposed worm was accounted for Rye flour is more apt to become acid than oatmeal # Cal. sometimes by its irritation produces convulsions I have known a family, all the children of which were thrown into convulsion by cal. & I was obliged to be very cautious & use blue pill injections etc. There are several milk remedies such as dandelion which is tonic laxative, & deobstrument acting on the liver, mullein fl. elder [blo??] tea “The pollens of most plants has a laxative quality” I have seen no danger from the prussic acid of the [illegible] flower & it is much used [illegible] from [illegible] also among the French they hold a place the French Pharm. Wild liquorice [gal??] [Circa???] resemble the dandelion Moderate friction excites the bowels Sometimes alkalie or chalk, though generally they are rather constipating, prove laxative probably on account of the acid combining 12:c. II II Where is a tendency to costiveness, the use of oatmeal gruel or porridge will be beneficial or a porridge made of wheat flour with the bran, strained through a cloth & mixed with the milk with which the child is fed also rye meal gruel or rye bran gruel If the health is not affected by the constipation be cautious about giving much medicine. It is always better to cure this affection by food than by medicine. # Castor oil from a teaspoonful to a table spoonful is the best cathartic magnesia given with the milk is a good remedy but not always sufficient. Elixir salutis is one of the most common family medicines. This article with castile soap dissolved in it has been found very serviceable. The gall of animals may be recommended. The blue pill operates gently as a cathartic & is useful in changing the habitual disposition to costiveness. I have prescribed with advantage decoction of the flowers of the dandelion, or mullein. The flowers of the peach tree are much used for the same purpose but “are rather too powerful for ordinary cases” “They are powerful even for adults” & sometimes gripe unless combined with aromatics Calomel may be used with safety # “In severe cases mustard and ginger may be applied to the abdomen” Mechanical manes in the form of suppositories are much used by nurses such as a piece of molasses candy or a roll of paper moistened with oil. They are beneficial. # If the child has been weaned pay particular attention to its food. Nurses are very careless. # “No serious evil will arise unless young & anxious mothers should give medicines and thus make the child sick” “If vomiting arises from dentition we must remove the irritation Give laxatives, as magnesia, & narcotic Children should be early accustomed to the reception of enemata to prevent subsequent prejudices upon the subject. I recollect the case of a child about 12 who was suffering from an obstinate constipation caused by an affection of the lower spinal nerves which produced a partial paralysis of the rectum and bladder so that a catheter had to be introduced & injections were [illegible] demanded. But all the efforts of the nurses (women) were unable to administer an enema Calomel had been given until the mouth was affected, yet without producing an evacuation. Finally the patient went into an insensible state, and injections were given & produced free evacuation. I have heard adults say they would die before submitting to receive an enema. 12:d. Vomiting Spontaneous vomiting in infants arises from over distention of the stomach. The discharge is made without nausea & almost without effort, & consists of pure milk or milk coagulated. The mother should simply be cautioned not to allow the child to nurse so long at a time. # Children and old people vomit with more facility than the middle aged If vomiting arises from the sympathy of the stomach with some other part of the system which is in a morbid state, the primary disease must be first cured & used for the irr. of stom. For the vomiting itself in palliative we may prescribe lime water & milk. a teaspoonful of each; soda water, or any liquid affording an abundance of carbonic acid. Vomiting from irritability of the stomach or free [illegible] requires particular attention. The attendant symptoms will be paleness of the countenance, quick & feeble pulse, & cold extremities. Irritants must be applied over the region of the stomach. They may consist of ginger, mustard, horseradish leaves, mint etc. aqu. amm. [illegible] essent oil dissolved in alcohol” The alkalies such as pearl ash, also soda water “lime water” may be given internally. Excite a discharge from the bowels by injection or a calomel cathartic to remedy the irritated action of the stomach “[illegible] counterirritation” The warm bath will be very serviceable, soothing the nerves of the skin & by sympathy producing the same effect upon those of the stomach nervines also may be given We may try putting a little brandy into the mouth or a small quantity of capsicum tea. Hot cloths & fomentations may also be applied externally. A large bulk of warm water water may be thrown up the rectum in obstinate cases, use stimulating injections.. One of the most convenient modes of administering a large injection is by a pipe fastened to a large ox bladder Press the fingers against the end of the pipe which the bladder is fastened so as to make a valve and prevent the escape of the fluid contained in the bladder, until after the pipe has been completely introduced into the rectum # I used to carry this recipe about me when I practiced in the country Frequently irr. of stom. is overcome by irr. o f the rectum by an enema of salt & water or by a large injection to produce a peristaltic motion downwards 12:e. Ren “Remove the cause, which is frequently indigestion. If it proceeds from the teeth, lance the gums The following is an excellent recipe # in these cases Rx Cret. ppt zii sem. card. zi bi carb. potas. zfs grind aqua bullientis 0 fs Give a tablespoonful every half hour I am inclined to the opinion that the alkalis, such as pearlast act by creating an excitability Emetics are particularly safe for children much more so than for adults. Ipecac is generally the best unless the disease in which the emetic is indicated is very threatening, when antimony should be used Squills are indicated in emetic doses in complaints of the chest “with [illegible] [illegible] but should not be administered when there is much inflammatory action in the system. “Warwick’s powder a preparation of antimony, was once popular and often administered without the advice of a physician. I have known it endanger life Nurses should never prescribe antimony” Some situations are more liable – low situations [seashore] Children shut up in low dark apartments suffer from want of amusement. If a diarrhoea from teething is suddenly stopped the brain is apt to be affected. This affection of the brain is peculiarly liable to occur in children. There is no outlet to the brain 12:f. Diarrhoea This complaint sometimes affects children for months & even years Some families are more subject to it than others & I have known those in which all the children would be affected with diarrhoea from a period soon after birth until they were three or foru years old. The children who have this predisposition to the disease are born with diseased liver and bowels & have indeed all the chylopoietic viscera in a disordered condition. Hence among the causes of diarrhoea we may rank a bad constitution. Other causes are want of cleanliness, bad food “want of sufficient clothing” bad air damp rooms, confinement & want of exercise. Exposure to cold & moisture A bad air probably causes diarrhoea mainly by its depressing influence. The effect of confinement and want of exercise is very great. Young animals suffer in the same way Even vegetables seem to need motion for I think I have observed a great deficiency of fruit & a sickly appearance of fruit trees after a season uncommonly free from wind. Confinement is injurious in another manner Children need mental stimulus from a variety of external objects. I have known surprising cures effected apparently by the operation of this very principle. Teething is a frequent cause & whenever it is we must palliate & check, but may not stop the diarrhoea From the sudden stoppage of a diarrhoea during dentition you may expect an affection of the brain to follow. The discharge from the bowels in this case is similar to that of tears from an irritated This will be convenient in many cases as in travelling Other mints may be used spearmint is most agreeable I have given this in the latter stages of the diarrhoea of adults with advantage Almost any cath. will often check a diarrh. Cal or blue pill is generally best Judgment is to be exercised whether to prescribe an emetic or a cathartic & as to the choice of a catheter Ipecac however is almost always safe children bear emetics well Put the parents & the nurse upon investigating as to [diet] Persons are apt to very careless about giving things to children And they may have wrong notions as to particular articles Prohibit solid oily food, crude vegetables and esculent roots. Potatoes are very bad in diarrhoea so are the analogous roots. They contain indeed much fecula, but also much 12:g. eye, or of mucus from the lungs The expressed juice of mentha vulgaris, boiled skimmed and mixed with white sugar is an agreeable, & useful article for the cure of a diarrhoea, which has continued but a short time & is not severe. In the early stages of a diarrhoea, which is sufficiently severe to demand the attention of a physician it will generally be best to commence the treatment with a cathartic; though if fever accompanies it an emetic of ipecacuanha should be the first article administered. Judgement must be exercised in the choice of a cathartic. Calomel will be best if the child be not particularly feeble or of a very delicate constitution & for a feeble child the blue poll. I myself was for formerly many years unable to take any other cathartic than the blue pill without being griped. Generally it will be best to combine chalk with the calomel, as the latter is indicated for its deobstruent, rather than for its purgative effect. The dose may be about 2 gr. cal. with 5 or 6 of chalk If improper diet is the cause the food must be changed; & it will generally be necessary to be particular in our enquiries with regard to the diet for the parents may consider many things a safe which would be strictly forbidden by the physician. Especially will it be necessary to attend to the diet if the child feeds instead of sucking. Every thing hard of digestion, such as salted & oil food should be prohibited The diet should be arrow root and in case of diarrhoea this article will be improved if prepared with a little laudanum or wine sago taipica, which is probably a hydrate of besides They are apt to become acids & acrid in the bowels. In the Polyn. islands The inhabitants living upon taro are very liable to diarrh. West of the Rocky Mts Lewis & Clark found the inhab. subject to diarrhoea for living on a root [illegible] [illegible] men suffered in the same way after they arrived among them In the evacuations & the evacuations of children shd always be exam [may] [illegible] that potatoes remain undigested Cullen & Rush thought different of potatoes The evac. of chil. should always be [illegible] Pies cakes articles containing much sugar hot bread should be prohibited Bread shd be toasted The juice of meat will often be beneficial No gravy (i.e. artificial or carbonized fat with flour etc.) Potatoe starch, pure, is perhaps not inferior to the tapioca etc. Boiled flour becomes s hard as stone almost hydrate It is an old practice It is an excellent preparation make a porrige of it grated Tapioca I suppose is made by sprinkling casserva root, powdered, with water & baking it making a preparation what appears like gum arabic. I have not been able to learn how it is made, but have made it this way a similar substance of arrow root Arrow root & the tapioca are cooked by first dissolving them with a small quantity of cold water & then adding hot water. In this way [illegible] are avoided 12:h. flour or roasted or baked flour made into a porridge with equal parts of milk and lime water. The bread should be toasted and butter should be used very sparingly gravy not at all. Casserva sago etc. An article similar to tapioca, if not the same may be made in the following manner. Tie up a quantity of wheat flour tightly in a clean cloth & boil it for 5 or 6 hours The result will be a hard substance which is to be grated & “[illegible] milk & water or with lime water” made into a porridge this will be palatable & good Rice in gruel, or thoroughly cooked by boiling The worst cases of diarrhoea are attended with feeble pulse, cold extremities, dry skin, & generally a rise of fever once or twice in the 24 hours. Soften the skin by the tepid bath which is [illegible] etc. and keep up an action on it by flannel unless there is fever & in such cases use also absorbents freely with tonics & aromatics. The chalk julep or white decoction will be as good a preparation as any. Rx Chalk [illegible] zfs to zi pul. cinnam. to zii zii, bum arab zi carb. potas. zi water lb I. boil ½ hour Sometimes [illegible] a similar recipe shd be used” The Europeans add [illegible] use [illegible]” a little laudanum may be added. Of this feed freely, giving say a table spoonful from ½ tab sp. to I once in an hour sometimes. As a tonic the vitriolic or tonic solution of Moseley is inferior to none in such cases Rx zinci sulph ziii alum zi water lbi Give from four to twenty drops. Tonics must sometimes be combined with absorbents Opium is always safe in cases where the bowels have been thoroughly evacuated. It is generally better to combine it with ipecac, which will determine its action to the skin and act as a gentle tonic & laxative The tepid bath is [illegible] as it may be called) relieves the irritation of the bowels through the skin Chalk does not act mechanically or chemically it has a specific action upon the stomach as much as bark Make white decoction in various ways if cinnamon offends use some other spice Sometimes add astringents or [illegible] Tonic sol. sulph [illegible] ziii al. zi Mosely sometimes used al. zii In 3 or 4 gtt it is anti emetic In larger doses it may be emetic & cathartic This is a state of the system similar to the collapse of cholera Asiatica It is a collapse taking place during diarrhoea. I have found advantage from stimulating or acrid injections as salt & water, mustard In chronic diarrhoea opium is often invaluable. Some families are obliged to give it 2 or 3 times a day for along time to their children until they are so old as not to be liable to continual diarrhoea The stools may be green clayey from deficiency of bile sour curdled [illegible] or very fetid, so much so as to be very offensive turning the stomach of the attendants. 12:i. In cases of chronic diarrhoea where there is attending it much sensibility and irritability of the bowels opium combined with diaphoretics cathartics or tonics is an invaluable remedy Sometimes violent symptoms supervene vomiting supervenes & the diarrhoea stops the patients hands & feet grow cold his pulse grows small, & if the most active measures are not take used the patient dies in 24 hours. When this change of symptoms take place we must resort to the most powerful means of exciting counterirritation such as application to the epigastrium of mustard, horse radish leaves ol. monardae punctulae, ol. turpent. etc. Such articles as pimento will be grateful and stimulating given internally We may give calomel, opium & the carbon. acid, and use stimulating injections. “Effervescing mixture with SS. [illegible] appt” Particular attention should be paid to the kind of They may be sour & curdled, or mucousy, [illegible] clay colored, water stools for much may be learned from their inspection. Acid is often formed in the whole alimentary canal, producing sour and curdled stools which will indicate lime water or other absorbents, with aromatics. The acid may arise from fermentation or more probably from secretion Such cases I have often cured by the expressed juice of the spear mint prepared as above mentioned & given freely. When the stools are green white, or clayey, give opium to allay irritation. Ipecac to equalise excitement, & the blue pill as a deobstruent, the latter in small doses so as to move the bowels, but once or twice in the 24 hours. Alkalis are useful as # Noel’s plaister was made of white lead red lead castile soap and olive oil, boiled till the red lead was so far decomposed by the oil that the mixture was of a cream colour It is a smooth plaister and is less stimulating than [illegible] Use soft charcoal by burning cork, which is the popular kind or cedar Dose teaspoonful to a tablespoonful in a convenient liquid Lime water & other alkalies may always be given They may be mixed with the food without [injurious] the taste When the disease has continued long & patient is [illegible] phlegmatic temperament we may bandage the bowels, to give mechanical support [Opium] also will be useful applied externally in this way Adults from the Wt. I. with chronic diarrhoea will look like a mummy Bog water is a very soft water & contains carb. hyd. Astringents [illegible] tinct. vitriol decoct. of oak bark with milk & sugar & spice Bandaging & plaisters Take any adhesive plaster and mix about ½ opium Or soap and opium Acetate of lead is not a new remedy 1 2 or 3 gr a day 1 gr at a time continued as long as the relaxed state of the bowels continues as long as they last lead [cholic] cannot take place for 12:j. are also enemata formed by dissolving castile soap in mallows or catnip tea. If there is much griping with tumefaction of the bowels injections of camomile tea give great relief. In diarrhoea of this kind the following is also a good stimulating & correcting laxative Rx castile soap zi elix. sal. zi dissolve & give it 3 or 4 times a day of teaspoonful or ½ teaspoonful doses. If the stools are fetid give charcoal internally. It will correct the fetor & it sometimes cures the disease. For sour stools vie last paragraph of this lecture During the long continuance of chronic diarrhoea it will of ten be advisable to apply mechanical support to the abdomen. We may apply a plaister of white diachylon [illegible] plaister alone or with opium or of lead and soap & a bandage. In chronic diarrhoea the skin becomes brown, of a dark & dirty appearance, & very dry and husky If the tepid bath does not relieve this symptom, we may apply water from peat swamps, which contains carburetted hydrogen. Vide Duncan’s commentaries In the last stages of diarrhoea we must resort to tonic solution to astringents, absorbents & aromatics we may also use opium with cathartics, emetics & absorbents & If we met with a great craving for salt food it should be gratified. The gratification of such an appetite will prove a stimulus, especially to the mind & consequently the more powerful. We meet with similar cases among adults also. Case of a man who could retain no medicines upon his stomach & finally recovered upon bread & cheese, given at his request In the latter stages also of chronic diarrhoea, acetate of lead the [illegible] [become] very lax and there is generally a prolapsus ani patient being [semiphlegmatic] I saw this article much used in this way when a young man and though expecting bad colic no injury resulted. Prof. Smith was very fond of chocolate [illegible] It sometimes acts like a charm Spiraea may be given in decoction or extract. [illegible][illegible] is not so good being unpleasant having a fishy taste & offending the stomach Ger. mac. & [illegible] [arom.] are pure astringents & unobjectionable on this score. I have prescribed sometimes one, or another, according to convenience of locality where I happened to be The root of typh. latif. is used as food by the aborigines European physicians give [althea] [illegible] which is the true marshmallows Usually when diarrhoea has continued long the kidneys become affected. Mucilage will then prove diuretic probably by their [illegible] affect. The terebinthinates will then be useful. The most common practice in this neighborhood is a decoction of white pine bark especially with a little milk it is called healing to the bowels. There is also nutriment in it for the aborigines, sometimes live on it When mucilages to wear out we may resort to terebinth. The species of [polygnomic] knot grass are 12:k. may be given internally. There will be no danger of the production of colic, by this remedy, for the bowels are too much relaxed. The astringents just mentioned may be various We have at least fifty indigenous vegetables, which may be used given in decoction of milk or water such as the bark of the currant, the raspberry, the various species of oak, of viburnum chocolate of acorns etc. white pine bark in milk etc. the roots of the [illegible] of the [geranium] etc. The viburnum Especially deserving of recommendation are the spiraea tomentosa & cornus circinata. The latter of which equalises excitement Of mucilages we may have occasion to use a variety for irritation for any one article may become worn out & another be more grateful We have typha latifolia, twigs of sassafras, hibiscus, malva bran, flax seed, slippery elm, gum arabic etc. all the mallows, all the [illegible] marshmallows hibiscus palustris called rose of [illegible] in the gardens root is [illegible] [illegible] & sub astringent Sour stools Be particular in forbidding the use of animal food. If there be want of bile, give ox gall, lactescent plants dandelion etc. with mild mercurials; e.g. calomel 2 gr. with 6 gr. chalk. Aromatics also may be combined. Astringents elg. [illegible] speraea cornus & geranium do well. Also the following Rx calc. magn. zfs rhei palm. gr. 8 acaciae zi ol. anisi gtt vi aquae purae zi Give a teaspoonful at a dose. “once in 2 hours” In bowel complaints with griping attended with green or sour stools Rx magn. ust zfs pulv. rhei grs viii pulv. gum ar. zi ess. menth pip. gtts vi water zi dose, teaspoonful Spiraea & cornus used – they are mucilaginous sub astringent & diuretic Articles of a stimulating kind are often needed in the latter stages especially erigeron canadande (colt tail) [illegible] The bitter [illegible] which grows in similar situations (ambrosia [elatio??] is also used as a bitter apparently nervine in diarrhoea Roman wormwood) [Cupron] is acrid, sub astringent & diuretic much used in the middle states improper when there is entonic action case of cholerine cured last summer by this garden young man called etc. chewing the plant etc. The other species of erigeron have similar properties espec. E. phil. Various recipes are given for diarrhoea in children Ex mag. zfs rhei gr. 8 [illegible] zi ess. pep. gtts 6 gum ar. zi The popular remedies are generally absorbent [illegible] mucilaginous astringent etc. Much benefit may often be derived from copious mucilaginous injections mutton broth is the most popular probably other broth (fat meat) would answer still mutton suet is less apt to become rancid. It is thought to be useful also as nourishment I have not though much of this may of nourishing Laudanum may be added Also laudanum & starch injections may be advisable to check the excess of the discharge It will generally be best to begin with about 10 drops of SS. though a teaspoonful may be required vide p. 2 [illegible] 2 12:l. Prolapsis Ani This is a troublesome symptom which sometimes occurs in diarrhoea. The protruded intestine should be immediately replaced. Most writers recommend to do this with a dry cloth, but this will irritate the sphincter ani & make it contract. The smoothest and least irritating article within my knowledge, is the crop of a fowl, or the neck of a bladder, turned inside out & filled with warm water # Afterwards we may apply astringent washes & injections of white oak bark or other similar articles, or of acetate of lead. The latter article may also be given internally in doses of from 1 to 2 grains. It will have a tendency to overcome the relaxation. Astringents are multitudinous & have had a specific [illegible], which proved to be the bark of [?strea] virginica At another time I had a specific sent me which proved to be viburnum sentago all the vib. are astringent Prolapsus ani “The part is relaxed and passes down and is then strangulated by the sphincter. For a permanent cure we must resort to astringents & tonics, but the part must be [illegible] by mechanical means If the intestine is not replaced, [illegible] or suppuration will be the consequence” “Take 1 bladder, cut off the neck, turn it inside out, fill it half full of warm water, and tie up the neck” “This disease was very common at the commencement of my practice but is now rare. The change has arisen in a great degree from the more correct notions respecting the proper management of the mother and child which now prevail. It is possible however that it may appear in [epidemics] and that case we should expect that it would appear for a time and the disappear # It frequently follows other diseases both in children and adults # According to the law of contagious diseases and that it is of no use to prevent it # Heat is a stimulus but too much of it produces a debility which may be [illegible] perhaps in direct debility “Since a free ventilation of nurseries has been practical the disease has been rare. laying aside the use of the preparations of alcohol has also been beneficial.” 13 Aphthae or Thrush White thrush from [illegible] (to inflame) This disease often appears within the mouth is then generally unaccompanied with fever. In some cases it is idiopathic but it more generally is a consequence of morbid affection of the primae viae # It is frequently found in adults of robust constitution which have been very much debilitated by previous that disease infancy and old age are most subject to it & in infants, as was just mentioned it is often an idiopathic affection In some families every infant is several with this affection. The vulgar error however, which very generally prevails that all children have the thrush at some sooner or late period other # is contradicted by the fact that many children as I have known never have the least appearance of it at any time “and it may probably in all cases, be prevented” The most feeble and delicate children are affected with the most violence, hence & from the fact of its being an affection of old age & a frequent sequel of other disease in adults, it may be inferred that this is a disease of debility & this [illegible] will be confirmed by the predisposing causes which we find to be, confined air, a very hot room & improper food# It is caused among the poor by bad air & among the rich by too great warmth & confinement. The fever likewise which accompanies it in many cases is of a typhoid character. # “Caused by neglect of the nurse by want of cleanliness & is often the effect of costiveness” # And have been led to prescribe remedies to prevent the thrush “commences on the inner part of the lower lip & corners of the mouth & extends over the tongue & inside of the cheeks & gums sometimes all these parts are affected & sometimes only one of them” “It appears in small eruptions or vesicles containing a whitish fluid resembling a coagulum of milk these vesicles often coalesce so as to form patches” “extend down the oesophagus to the cardia & here in all known cases it has stopped” Prof. Tully has seen p.m. [illegible] which the thrush the al canal [illegible] “The feces are sometimes covered with aphthous sloughs” “in its severest the eruptions are of a dark brown or deep red colour” “The alvine discharges are very acrid” 14 Symptoms – The disease is preceded by languor and sleeping This is so generally the case that it is common for nurses to say that the child is sleeping for the sore mouth In adults I have observed the same fact, & have predicted the appearance of thrush from the drowsiness of my patient # The symptoms of thrush are very obvious. It commences with white specks upon the lips #, angles of the mouth, & tongue effervescence. # In severe cases the specks in crease in number and size until they cover the whole inside of the mouth the throat & are found indeed upon the stomach x & throughout the whole intestinal canal though this is disputed. One thing is certain, whether these specks or flocculi extend throughout whole alimentary canal or not, viz. that they are found upon the rectum, agreeably the law that the orifices of tubes are most affected The white crust will fall off and be succeeded by one of a darker colour. The coats of thrush are often many times renewed & in this case the formation of a new one is preceded by unusually protracted sleep. A typhoid fever may accompany. It seems to be an eruptive disease determined [illegible] the al. canal. “In its milder form it is confined to some particular part of the mouth or to the mouth itself. The eruption is white & the mouth appears “as if a stratum of coagulated milk were spread over it” & but one separation of the curd like crust will take place. The general health will be but little disturbed” “In severer cases two or three successive crop are formed & the habit being unhealthy, the food innutrient, & the frame weak and atrophous, the under [surface] ulcerates and spreads & a low typhoid fever ensues” # “Your principal object should be to produce an excitement in the bowels by some mild medicine” # Because it is an eruptive disease however diaphoretic seen to be indicated & those which [illegible] action “The treatment is ordinarily a gentle laxative but there is a choice in the kind of laxative. Some practitioners recommend oily medicines, as butter, goose oil, pigs foot oil etc. But these articles do mischief As the vital powers of the stomach are weak, these oils will become rancid” # In such circumstances the oils become rancid & consequently irritate. I never allow oils to be given, yet it is a common practice to swab the mouth with oils, especially goose oil (or [illegible]?) # Chalk shd generally be preferred the other articles dissolve more slowly & may act in part mechanically” 15 It is thought that this disease has often been prevented, by giving soon after birth a teaspoonful of cold water & repeating the remedy every morning, for some time taking care also that the bowels be kept open There may be some foundation for this belief inasmuch as the disease is brought on by heat and debility. “In families where the children have uniformly been subject to this disease. I have recommended cold water as directed that the room should be well ventilated and the child not covered with too much clothing” In mild cases & where the constitution of the child is robust, a gentle laxative will be sufficient to remove the complaint # Castor oil is very often prescribed for it & it may be proper to five it to assist the operation of other cathartics But there are several objections to this article. It does not affect the secretions so much as other cathartics. It does not evacuate the contents of the bowels so thoroughly as others & it tends to # relax the coasts of the intestines, already in a state of morbid relaxation “It will not remove the mucus of the intestines” For mild cases magnesia is the best laxative where it can be given in sufficient quantities. If the bowels should not need a cathartic chalk or some one of the other testacious powders may be given “as [illegible] oyster shells, crabs eyes, crabs claws etc.” # Because it is an eruptive disease however, diaphoretics and articles which translate action seem to be indicated # “Give at first the clear liquor of this infusion and if this does not operate stir it up and give the substance (1) “After the stomach and bowels have been evacuated the ipecac should be given in small doses ¼ to 1/6 of a grain, to keep the bowels open, to produce a tonic effect, to determine to the surface & to prevent convulsion Ipecac has more claim to be considered as a specific than any thing else. It obviates the morbid secretions of the bowels it acts as a tonic never produces unequal excitement or other tonics & it does not like astrigents produce constrictions Whenever there is a tendency to unequal excitement it must be obviated or tonics will do no good” # I rely upon the ipecac though I use [illegible] sometimes especially white root asc. tul. # Indeed “if diarrhoea is present, prepared chalk is a good remedy as is also charcoal: the best form of which is burnt oak for this can do no mechanical injury” # “I have found this almost a specific” Since I have used this treatment I have not lost an infant by this disease” Ipecac in small doses as an alteration approaches as near to a specific in any remedy can # which is not to be expected # Astringents must be avoided, though tonics are indicated because they produce unequal & local excitement & stricture they must be given in the latter stages after excitement has been [equalised] A little borax may be given Moseley’s solut. zinc ziii al. zi [illegible] 1 pt 16 In the commencement of the disease if the symptoms do not indicate the probability of a severe case an emetic of ipecac is the best remedy Antimony has been recommended but it is not a safe emetic for children within the mouth Infuse [illegible] of ipecac in 6 teaspoonfuls of warm water & give a teaspoonful every half hour until the patient vomits or purges. # Ipecac has the advantage over antimony in its tonic and antispasmodic properties & in the mildness of its operation, never producing alarming symptoms # If the ipecac empties the stomach and not the bowels, a blue pill should be given of the size of from 2 to 8 grains. If this be found insufficient, it may be assisted by a dose of calomel, or magnesia or an enema (1) After the bowels have been thoroughly cleansed the ipecac should be given in small quantities a fourth or a sixth of a grain to determine to the surface & to prevent convulsions # If this dose moves the bowels too much, we may add “[illegible] or 1/6” one sixth of a 1/8 drop of Laudanum to each dose The absorbent powder or the white decoction may be given at the same time# Astringents should be cautiously avoided until the stomach and bowels been thoroughly evacuated # “& if there is much fever” Where this has been done we may make use of Moseley’s tonic solution, or cornus [circinata] [illegible] alba, or sericea or saffron safely & with advantage It is to be remarked that chemical action is prevented by the vital principle acting upon the food or articles introduced introduced into the stomach, and putrefactive or [acetous] fermentation if the vital powers of the stomach are [vigorous] This principle applies to vegetables Plants taken up in full blown in August and packed in live [sphagnum] will be preserved by the life of the sphagnum In thrush the powers of life are weakened & not only substances taken in but the secretions themselves are subject to fermentation hance the use of obviating the effects by alkalies limewater magnesia, chalk [illegible] absorbent powders white decoct. Rx. “To prevent the increase of vesicles of effervescences, syringe off the acrimonious fluid as well as you are able, by some diluent or detergent gargle and expedite the separation of the sloughs by invigorating astringents” vide Dr Good vol [illegilble] p. 30 “A little borax & ergot may be put into the mouth. But if the mouth is dry & parched, this and other astringent shd not be used. In such cases we should give mucilaginous substances as gum ar. slip. elm. or sassaf X 5 or 6 gr a drachm? of each in a gill of water # or viola pedata (parsley violet) or comfrey We must be very cautious about administering it to infants 17 To correct the acidity which often attends this disease we may administer prepared chalk or lime water & milk Or Rx magn. usta 10 or 12 fr. elix. pareg. xx gtts water zi given in teaspoonful doses every hour If the stools are watery and the child is robust give coct. ppt # vi gr. cal. 1 gr or the compd powder of chalk in doses of vi gr. or a small quantity fo rhubarb instead of the cal. For watery stools give dal. 1 gr & chalk 6 grs or compd powder of chalk It is too much the practice to scratch or rub off the aphthae in a violent manner with a brush or swab. As well might the cure of any other eruptive disease be attempted by violently rubbing or scraping off the pustules. Rubbing the mouth with a brush or swab until the bleeds is a cruelty which ought to be deprecated Still something must generally be done to the mouth in order to satisfy the importunity of nurses & prevent their mischievous attempts A little borax and sugar X is as safe as any thing If the mouth is dry it may be lubricated with muc. gum arab. slippery elm or sassafras twigs When the mouth is in a very high state of irritation probably a small quantity fo sugar of lead would be serviceable. I have not myself ventured to administer it to infants within the mouth For the proper local treatment of ulcers vide ulceration of the mouth From the sympathy which exists between these parts and the surface, tonics should be combined with diaphoretics I have given [illegible] [has] or [illegible] it is [illegible] observed by tonic and determines to the surface # It is mucilaginous sub-emetic & diaphoretic. It may be given freely as a wash or administered freely internally laxative diaphoretic soothing antirritant “The other [illegible] may be as good” The disease of which we have been speaking is a local disease 18 Ipecacuanha in this disease is emetic, tonic, diaphoretic etc. alterative & since I have used it I have not lost a single infant with thrush The viola pedata (parsley violet in some degree resembles ipecac is its qualities & may be internally administered in its stead # “give a teaspoonful of of the decoction” The peculiar kind of thrush of which I have been treating is a local eruptive disease of infants but as it appears in children more advanced it a critical determination of diseased action. It is not unfrequently a favorable symptom, particularly when it succeeds strong morbid action & [illegible] early in the disease In the latter stages & when the system is exhausted it is unfavorable For instance in hydrocephalus, when the whole mouth will sometimes become sore, and the disease seen to be translated to the mouth “from the brain to the muc. memb” In the latter stages of any disease not so fatal as hydrocephalus it is a very dangerous symptom of exhaustion “In cholera infantum it is a dangerous symptom. [illegible] there is not translation from [illegible] essential part” 18 ½ Eruptions in General Children of all ages are subject to various eruptions These are generally occasioned by the quantity or quality of their food. They are frequently cured by change of diet alone & the greatest attention should always paid to the diet is managing them Oily food particularly nuts, must be strictly prohibited, as they often cause eruptions. I have known some adults invariably affected with eruptions about the lips or other parts of the face after eating freely of walnuts Fish & poke week may likewise [illegible] the eruption We may use the tepid bath for the purpose of cleansing the skin. The frequent use of the [illegible] bath is important especially in chronic eruptive diseases of children & adults vide p. 21 & p. 20 For infantile [illegible] [illegible] p. 1831-2 of Good Case of a peculiar eruptive disease vide [illegible] [illegible] P. 1831 1 [illegible] art. The eruption was periodical, appearing at a certain hour every day At first a light coloured opaque elevation of the skin about half an inch log & a quarter broad like the sting of a bee or wasp. Soon after their appearance blood began to ooze from them & producing a drop which concreted into a scab, & at the end of 3 days fall off 8 or ten eruptions came out daily. Treatment was ineffective until a change of air & diet, which effected a cure “Child 8 or 10 yrs of age about 5 p.m. it would complain of a pain in the face then would appear elevation of the skin to the number of 10 or 12 the issue was treated as if [illegible] bark was tried also nit. sil. sulph zinc. arsenic & other minerals emetics cathartics new diet finally fruit was recom ate freely of oranges & was benefitted. Then change of air & travelling were tried or the first day the eruptions diminished & on the third disappeared In such cases try changes of mineral waters & dieting” 19 Red Gum Allied to thrush is that eruption called red gum The original word was red gown (from a sort of spotted red calico) which has been corrupted into red gum It is called by [Willa??] strophilus intertinctus It is a populous eruption & said to be peculiar to children but this last is doubtful The eruption is sometimes confined & sometimes diffused over the whole body. The papulae rise above the skin are distinct from each other & of a rarely contain lymph bright red colour. The vesicles contain by [illegible] only & terminate in scurf. Afterwards subsequent eruptions makes their appearance. The constitution is rarely affected. Physicians are not usually called unless the nurse is inexperienced Nurses give saffron Some physicians suppose this disease to be the same with aphthae. Dr [Willan] thinks they alternate. Dr Russell remarks “I think that aphthae of infants is of the same nature with those eruptions called red gum & differs in this respect that one disease affects the skin & the other the internal surface of the alimentary canal. Dr [illegible] thinks that this affection, preceded by sickness, arises from causes similar to those of aphthae, such as confinement, heat, irritable state of al. can. indigestion [illegible] If the disease be suddenly repelled from the surface, vomiting & spasmodic affections take place. Hence the European physicians Belonging to the primary [page] Probably the patient was not dieted so strictly as was intended & I recommended change of air Oranges however were beneficial. The was too fond of good living, fond of oily nuts There was a slight reappearance after it but of short continuance It was called [illegible], but improperly The eruption was preceded by a warming sensation of pain in the part. “Red gum is an eruption of fine pimples of a red colour affecting infants [illegible] within the mouth. It is a disease that rarely requires the advice of a physician The cure is much better effected by diet and [regimen] by the exhibition of medicines Still the physician is frequently called in and he must prescribe something if for no other object than to satisfy the friends In order any case give a decoction of saffron & snake root to keep the eruption from [striking] in & keep the bowels soluble with tinct. rhei compd tinct sennae magnesia, or other mild cathartics” 20 caution is not to expose infants with this eruption upon them to a current of cold air, or to plunge them into a cold bath. It is said that fatal consequences have resulted from such imprudence The child should be kept clean & be subjected to daily ablution of tepid water. Particular attention should be paid to the quantity & quality of its food. If the eruption should be repelled from the skin the tepid bath will be the best remedy This disease often occurs within the mouth & rarely requires the attention of the physician. [illegible] tone of the mildest of the eruptive diseases “We may give a decoction of saffron crocus? & snake root to prevent the eruption from striking inwards & keep the bowels soluble by mild cathartics such as magnesia & rhubarb. Still more will depend upon diet than upon medicine. Wine & water or one part milk & three water may be given” [belonging] to p. 18a “In managing most eruptive diseases more attention should be paid to diet than to medicine. In most cases it is requisite that the quantity of food should be diminished. If the food is milk, let it be three parts water, or substitute whey. Infants should take no animal food & no crude vegetables within the year. Oily food and the various kinds of nuts should be prohibited even for 2 or 3 years. A strong child in the country, with abundance of air and exercise might be indulged in such excesses with impunity when a feeble child in one of our cities would be destroyed by them” The eruption is so small as not to be observed It is not my object to treat of eruptions in general with minuteness but to give the general principles of treatment food etc. There are many eruptions met with [illegible] children which cannot be classed or be found described There is an affection of children appearing within the weak, which is not described at all. In three or 4 days after birth elevations of the true skin not of the cuticle upon the hands and arms & various parts of the body containing pus and [illegible] or as large, some of them as ½ dollar high [illegible] [fever] I have seen but few cases they were mortal. The books in such affections direct bark & tonics. The practice proved injurious. The disease as I have seen it has been inflammatory and required antiphlogistic treatment It may however be typhoid sometimes perhaps. If so it should be treated accordingly. I have seen but 3 or 4 cases. There were inflammatory. I prescribed in all these cases & from an analogy more fancied than real, between this & [illegible] Eruptions are generally caused by improper quantity or quality of diet. The remedies frequently get the credit of curing the disease when the amended diet cured the patient Oily & highly stimulating food should be avoided. All the nuts one of the worst is the pea nut 21 Strophilus candidus In this species of strophilus the papulae are larger then in any other of the genus. They are not surrounded with an inflamed base. They are very distinct smooth and shining & appear like little pearls under the skin of about the size of half a millet seed. They may continue for some time. A close examination is necessary for their detection. They appear on the bosom & chest They may accompany other diseases I have seen them accompany cholera infantum in the last stages & considered a fatal symptom [illegible] dyspeptic consumption a dangerous symptom The chest appearing to be covered with an oil surface, looking like particles of water I have seen persons attempt to wipe them off as if water had been sprinkled on the part Belonging to p 18 ½ Apples pears and fruits etc. Cleanliness also shd be strictly practised [enjoined] robust children, much in the open air, may have eruptions about the face mouth etc. with impunity when with the same diet delicate children, much confined, would have fatal eruptions, diarrhoea cholera infantum etc. The appearance of the [former] [have] [illegible] and the parents are often much alarmed. The disease is not dangerous however, & leaves no scar behind A scab is formed & the margin continues to suppurate and matter forms underneath “There is a thin [illegible] discharge from the part & the scab comes off leaving a thing pellucid [illegible]” The disease continues & this film is thrown off & the process is repeated 2 or 3 times It is sometimes occasioned by dentition sometimes it is an effort of the system caused by disturbance in the al. can. “A prejudice sometimes prevails with respect to this disease that it is an effort of nature & ought not to be checked It is a loathsome disease extremely unpleasant to both to the patient and the nurse & if allowed to continue some time it would not be safe to stop the evacuation, at least without keeping the bowels open” Some [Phys.] recommend partic [illegible] as specifics. Cal. or blue pill occasionally may be advantageous Buckthorn has been much celebrated in this and other eruptions It is drastic& hydragogue It is perhaps milder in form of syrup. Many families keep it. Half a dozen berries will operate If there is much plethora, the neutral salts may be given Magnesia also both for the indication & as a corrector I have known the muriatic ether much prescribed, but have not used it much myself, substituting for it mur. ac. as below 22 Crusta Lactea This is the [illegible] larvata of Bateman It appears on the lips, forehead & scalp in small pustules yielding pus, which eventually coalesce & form large loose scabs & perhaps extend over the whole face, down the neck and over the whole body. This eruption never leaves a scar behind it however long it may have continued. The skin is left smooth It is more unpleasant than dangerous, as the children affected with it are fleshy and otherwise health. When it has continued a considerable period of time, we must be cautious of checking it, as it is like a habitual discharge from an ulcer Treatment It is very common to give laxatives, such as syrup of buckthorn, neutral salts, magnesia etc. The sweet spirits of sea salt (diluted muriatic ether) is a very popular remedy. IT is given in doses of from 5 to 10 drops, diluted with water & repeated 2 or 3 times a day. I have seen this medicine given in hundreds of cases & am inclined to think it sometimes of service. It, at least give satisfaction to the parents & does no injury. If there is great irritability give 2 or 3 gr. of cal. with chalk. In cases where I have thought proper to remove the eruption. I have given the muriatic acid instead of ether, prepared in the following manner Rx mur. ac. zi alcohol zi Give [3] drops night & morning diluted with water make [oxyg.] oint. by adding the nit. ac. to lard until decomposition ceases, and the resulting ointment is tasteless. It has about the consistence of wax. Some add sulphuric acid but this is not decomposed & is acrid Sometimes the ointments seem to irritate & then we use [illegible] The best is the sulph. pot. zi to a porter bottle of water. Sulph. of soda does not materially differ, but it is unpleasant smelling like bilge water. In different cases apparently similar I have tried ointment & succeeded in one, but failed in another, & succeeded by waste I was led to adopt the use of sulphuret of potash from the analogy between its solution & the water [of] sulphur springs “We may with advantage make application of dry powders arrow root roasted flower hair powder taking care to give a cathartic when we check the discharge. We should pay particular attention to the diet both of the child and mother making the food weak & [simple] Laxatives will commonly be removed; a little magnesia & sulphur so as to move the bowels once or twice a day “A discharge like this may be checked with safety at the commencement, but when it has become habitual it should not be stopped unless a drain is made & kept open in another part.” 23 For this eruption I have found the oxygenated ointment, very efficacious in removing the scabs & healing the sores It is always safe if well prepared. ‘It is made by decomposing nitric acid with lard’ Perhaps the [citric] ointment (nitrate of mercury with lard) may be equally efficacious, but it is less safe. A good ointment may be made by mixing calomel zii with simple cerate zi or mutton suet zi The sulphuret of potash is one of the best remedies for this & other similar affections Dissolve zii in a pint of water & give a table spoonful night and morning also let the part affected be washed with a solution of twice the strength “It sometimes [illegible] two or three days and [illegible] [illegible]” Some prefer sulphuret of soda sulphuret of lime would also be equally efficacious Such solutions small like bilge water & are analogous to the water of sulphur springs I have sometimes used the sulphuret of pot. as an unguent. Sometimes liquid applications & sometimes unguents will succeed best, & if one fails we may try the other “Calomel ointment may be applied about the edges” If the eruption should suddenly dry up & fever ensue, a dose of calomel should be given & be followed by a few drops of antimonial wine 3 or 4 times a day or a small quantity of ipecac. White hellebore may be given Sometimes the eruption degenerates to a phagedenic ulcer. In such cases I have used charcoal eternally also a variety of poultices. I have seen much The const. irr. may expend itself upon the skin or upon the gland. syst. or upon the al. can. etc. We must be cautious about suspending them suddenly “It is important in all kinds of eruptions to keep the skin clean and soft & to effect this we should prescribe the warm or tepid bath, every day or 2 or 3 times a week. It removes itching and irritation, is always safe and almost always beneficial” May be caused by teething or by food etc. Such things often withstand various remedies & hence are prescribed for very empirically 24 benefit derived from the application of roasted flour. It absorbs moisture & excludes the air Eruptions attendant upon Teething Children are very commonly affected with eruptions when teething. They generally put on the appearance of a fine rash, but sometimes consist of distinct pustules containing matter As they are symptomatic merely, they require no particular attention to be paid to them & will disappear when the teeth get through. The worst consequences might result from their sudden suppression; as if this mode of action by which the system relieves itself from the irritation of the teeth, be interrupted, there is great danger that the system will relieve itself by morbid action of the brain, or other parts more essential to life Eruption resembling the itch Another kind of eruption appears on children of one or two years of age. It sonsists of distinct pustules like those of chicken pock, which form a scab, continue to inflame about the edges & contain a watery fluid It usually makes its appearance in summer & if not cured disappears spontaneously at the commencement of cold weather It has often been mistaken for the itch, and attempted to be cured by [?dock] root, but without success. The sulphuret of potash used as above is a good remedy The tepid bath is apt to be neglected but shd not Dock root often fails in this. It is often very successful in children’s eruptions. It is a very old remedy (centuries) Sometimes goes into oblivion & is again revived Prof. Smith thought most highly of R. patientie 6 feet high in gardens. Woodville mentions R [aquaticus] I know not that either is better than our [common] [illegible] I prefer the [Robtusifoli??] or [horserock] It is acrid and acts well when ext. [applied] and is good int. like rhub. R. crispus also has about the same properties but is milder. R. sanguinea is kept by many for it is as a specific for cutaneous eruptions. called also jaundice root & used in jaundice I have used them all and cultivated than all The leaves of the R. sanguinea have all red veins. You will often have such cuticles exhibited to you in families and be [illegible] of about them. Hence the importance of a knowledge of their prop. I have never known them in any but the children of [foreigners] I am inclined to think the taint may be dormant. The eruption at first resembles what is called “horn pock” “sometimes resemble a [illegible]” The nurse was changed & though the new one was health yet the ulcer appeared on her nipple 25 I think this kind of eruption might be cured by diet and the warm both. In all cutaneous affections the warm bath is very important to relieve the skin from every thing that may obstruct perspiration Eruptions & other irritations of the skin translate action from the viscera. Where irritated action exists in the viscera they are symptomatic Gutta rosea of drunkards is an instance of translation of action from the liver “When a cutaneous eruption appears we may generally apprehend that the al. canal is disordered” I cannot too strongly enforce attention to diet. Nothing will avail without it Venereal Eruptions These appear infants born of parents tainted with syphilis, though they may have no symptoms of it at the time of the birth of the child. Some physicians are of opinion that this child may inherit the disease from its ancestor the parents having been apparently free. The eruption appears in smooth hard, circumscribed elevations of the skin of about half the size of a pea 7 resembling a wart before it has seeds. They continue to increase slowly in size for two or three weeks, & become soft, containing a watery fluid in [honey] like substance Subsequently the skin gets rubbed off & leaves an ulcer with ragged edges & sometimes resembling a chancre which is very difficult to cure. I have known one instance in which the ulcer was communicated from the child to the breast of the nurse. Children affected with this Eruptions sometimes depend upon morbid state of the liver analogous to gutta rosea of drunkards Prescribe to the liver “The disease often proves very obstinate” Mercury does not seem to act as in the primary disease Corr. sub. given in this way is as safe as any other article The bowels should be kept free “I think the sublimate acts more on the skin & is therefore preferable to other mercurials” The plantain was once celebrated for the cure of cut. aff. I have known the plaintain in this way apparently cure after mercurials had failed Still the mercury might have prepared the system The plantain is an old English remedy for bites of spiders etc. It is treated of by Woodville & [Willan] It has as little acrimony I have some confidence in its efficacy. There is an old story about a snake & [spider] I have known nondiscript eruption which had resisted the prescription of several phys. cured finally by diet & change of air 26 complaint have a pale & bloated appearance & the powers of life are feeble Treatment. Change the nurse if derived from her Give corr. sub. in doses of 1/30 or 1/40 of a gr. Give the blue pill in moderate quantities but it subl. is better Give the tepid bath. Try the preparations of iron, such as the mur. ferri, or tartr. ferr. or the alkaline solution of iron. This complaint is not so easily cured as the primary [illegible]. Sometimes it will resist the operation of mercurials & all the treatment for scrofula. In this case send the patient into the country & try simple vegetable articles especially the expressed juice of the plantain (plantago major) externally and internally. It is a popular remedy for poison & is apparently valuable. I have known patients cured by the use of this, and of the air of the country. Still I think its main virtue to consist in its bland & mucilaginous quality [In these cases the whole lymphatic system is disordered & deobstruents are indicated. Now the expressed juice of most green vegetables id deobstruent. For instance the farmers make use of green rye in the spring for this purpose] Perhaps the expressed juice of the green plantain is deobstruent Infantile Erysipelas is an improper name vide Gray [illegible] of Erysipelas Good’s is an entirely different disease and his account will completely [illegible] Corresponds perhaps to the rose of the W.F. Goods account of the rash may do pretty well The infantile erysipelas of Europe described in the books is a different thing # Resembles shingles this is accompanied with fever The primary affection is of the al. can. therefore the attention is not to be directed exclusively to the skin I commences with [illegible] [illegible] you are to prescribe to the fever [illegible] This disease is distinguished by the eruption resembling a rose in the shading off of the colour from a dark rose to a light colour & in the concentric circles As I have seen the disease the rash has appeared in patches about the [illegible] thighs principally & the local affection gave no [illegible] and was trifling while the constitutional fever was severe and dangerous. The fever if not broken up in the commencement will resemble a severe case of [autumnal] remittent I have found no satisfactory account of the disease in the books, not even in the W. P. writers. I have however been informed a conversation with W. Indians that the rose is one of their most severe and dangerous infantile diseases fatal in a week and is treated by a vigorous administration of calomel # I have never seen the infantile erysipelas described as occurring in the European lying in hospitals contagious & terminating in gangrene I have seen common erysipelas upon infants however 27 Infantile Erysipelas The classification of this disease id doubtful. It answers tolerably well to the exanthesis roseola of Good “but [illegible] febrile” there is no species in Bateman & Willan which corresponds to it Efflorescence in blushing patches, gradually deepening to a “dark” rose colour, mostly circular or oval, alternately fading & growing brighter chiefly on the legs with irregular appearance somewhat like concentric circles if the patch is not circular the general circumference This is a disease of rare occurrence with us I have met with three or four cases. It is a severe and dangerous disease, apparently the same with the dangerous rose of the W.F. As it appears with us it is very different from the erys. that described by European writers & which is sometimes epidemic in their hospitals. In children in this country it is generally a disease sympathetic with a morbid state of the bowel The elevation of the skin is less than in erys. of adults the discoloration less deep in colour & the skin though a little tumefied is as smooth to the touch as if not diseased In the cases to which I just alluded, the erysipelas began upon the thighs & extended all over the legs. It was accompanied with considerable fever & a hot dry skin The colour of the efflorescence was purplish rather than red ‘We rarely see watery or bloody vesicles, as in other erysipelas’ I evacuated the bowels thoroughly with calomel (for the sake of the excitement rather than the evacuation) & rubbed the part affected The fever will much resemble that of infantile remittent “The spots are in patches from the size of a dollar to 5 or 6 times as large They are shaded in concentric circles from purple in the center to a lighter colour” “If the disease is not checked there will be increase of fever, constipation and tumefaction of the bowels irritation of the stomach affection of the brain, [illegible] death” Administer a full dose of calomel in the first place and repeat it once or twice. Work off the cal. with other cathartics. The secretion excited by the calomel is what we want. The cathar. subsequently given bring away Antimony in small quant. & nitre may be given until the liver is subdued “When the febrile symptoms run high pulse tense, tongue furred skin hot it is a very dangerous practice to apply discutients applications to the eternal affection Acetate of lead applied externally will probably translate the disease to the bowels” “Treatment I first give colored in full doses to alter the secretions to change excitement and promote evacuation, but do not depend upon it as a cathartic I then give [illegible] or [illegible] & [illegible] etc. to move the bowels I afterwards use the absorbants or alkalies, or ant. or iped. in small doses, as the case may require 28 It is attended with constipation & tumefaction & [illegible] of the bowels; with hiccup & severe fever, & may terminate fatally with severe coma “Pulse small & frequent child dies usually on the 5th or 6th day” “Dr Dewers says that in the cases he has seen the disease was not local but would spread rapidly over the body disappearing in one spot without leaving a trace behind it & breaking out in an other & perhaps a remote part thus changing from one end of the body to the other” Treatment. “Evacuate the stomach with an emetic, as ipecac” Clear the bowels thoroughly with cathartics, for the sake of the impression on the system. Give calomel in a dose of from 5 to 10 grs. If it do not operate within three or four hours repeat the dose. If necessary , work off the calomel with senna (or scammony?) adding aromatics if the stomach is irritable or with castor oil if the senna fails using also some laxative injection & the warm bath to assist. Then keep the bowels open with blue pill & “use some mild diaphoretic as aqua amm.” or give antimony from from 1/20 to 1/16 of a grain Pay little regard to the eruption and direct your attention to the bowels I have letters from physicians who have followed my directions & treated the disease not as a local one but with cathartics which testify the complete success of this plan of treatment. In the W.F. also where the “As palliatives after a strong impression has been made on the bowels by calomel, we may give sweet spirits of nitre, aqua ammoniae etc.” I have tried various either applic. without benefit I have “In those cases when the treatment wa local only the patients have uniformly died. I have not lost a single case to which I was called with commencement. I have conversed upon this subject with medical [illegible] out from the W.F. and find that the practice there coincide with mine” “When called to cases of some standing I have endeavoured to arrest the progress of the disease by a blister as [illegible] in gangrene & in the erysipelas of adults. The disease would extend beyond the blister just as if none had been applied” There is an erysip. affection which occurs about the head of children which resembles that of adults which I have treated with lead water 29 disease is frequent it is treated by the physician with calomel & cathartics. They give calomel 10 gr. & repeat it in 5 gr. doses until 20 gr. have been given I once saw a child with a swelling on one ankle supposed to have been produced by the sting of a bee or bite of a spider, which had resisted the operation of poultices & lead water. I gave cathartics but they did not operate, & the child finally died External applications of any activity should not be used, Still it may be necessary to apply something in order to satisfy the parents. The best will be roasted four “dried [illegible] [illegible]. Warm bathing will be very useful. If treated with lead water & cathartics not used, probably every case would be fatal. I have blistered in imitation of Dr Physick, but never with any advantage ‘If the disease be followed by diarrhoea give absorbents & aromatics such as compd powd chalk or white decoction. If followed by weak pulse etc. give tonics’ I have not lost a case when called early ‘This disease is supposed by some to be hereditary I have seen it affect infants on the scalp when it appeared to be a local affection merely In cases of this kind I have used lead water with [illegible] continualy advantage & without any evil consequences’ Cathartics however should be more or less employed in conjunction “afterward aromatics or tonics as the case may require” ‘It sometimes affects the brain’ [illegible] a more [illegible] or [illegible] intertrigo an attenuation & sometimes abrasion of the cuticle. The vessels forming the cuticle are diseased and the skin is formed in an imperfect manner It occurs also about the nates, [illegible] etc. where the skin folds upon itself & the air is excluded sometimes an acrid discharge Cullen thought it a very thematic affection. The skin looks like a new skin upon these parts. it arises from want of cleanliness & from confinement. The stomach may in a state of indigestion secrete an acid and the skin may secrete an acid. Exercise cleanliness treatment in general of eruptive disease When [illegible] flax they would burn a rag and put it in an axe & rub their finger on to harden the skin when chafed. A scorched rag is beneficial & use absorbent powders first nit. [illegible] might be used keep dry the parts Nurses apply “powder post” which is made by [worms] Sometimes it is a vesicular eruption which upon the head is called [farrigo] & in some situations is called ring worm To the [illegible] or intertrigo occurring in various parts the nurses sometimes apply the membrane from suet which is smooth keep off the air, prevents farther chafing and does well. The absorbent powders as starch alabaster etc. do well 30 Sore Ears This forms a very important subject in treating of the diseases of children. Nature has chosen the part behind the ear for eliminating irritation from the system. Under this head I shall speak of purulent discharges from the cavities of the ears & nose Slight blisters and ulcerations behind the ears of infants are very common & are in most cases, so mild as merely to require washing with cold water weak soap suds & with cold water, & being covered with a scorched rag or with roasted flour, to prevent irritation from the cap Frequently the discharge is acrid & excoriates the adjacent skin. Often a miliary eruption at the part commences the disease & is followed by excoriation Affections of the brain are sometimes relieved by a discharge from this part. The discharge is very important to children in time of teething & when affected with bowel complaints. If suddenly stopped fever may follow with full pulse, tense constipated bowels & fulness of the fontanelles & “often nearly all the symptoms of hydrocephalus” cold extremities Blisters behind the ears will generally restore the child to health When an infant is suddenly attacked with symptoms of hydrocephalus [illegible] disease, enquire whether it has had sore ears which have suddenly dried up, & if so, apply blisters behind the ears, for without them nothing perhaps will cure the new complaint. The same is true of old sore legs stopping of the [illegible] & other charges The theory of this, in all such cases, is the necessity, not The quantity of evacuation will not amount perhaps to more than a teaspoonful & the fullness of the fontanelles [rain] in the head & plethora is not owing to the quantity of fluid. The same plethora, pain in the head etc. will result from cessation of catamena which discharges will not amount to more than a table spoonful So you may bleed to the amount of pounds in cessation of a slight discharge for an old sore leg with out relief. while if you start the ulcer again by [illegible] or [mustard] the symptoms will be relieved Case of a man with ulcers on the legs of 10 to [20] years standing discharge stopped [illegible] pleurisy & aff. of liver the discharge restored by [illegible] blisters caustic etc. cure affected Sulphate zinc 10 gr. to oz or 2 oz may be applied Solution [illegible] sil. is one of the mildest application for irritated surfaces vide infra Oxygenated [illegible] is mildest & less apt to become acrid Sometimes when the aff is of an erysipelatous kind [illegible] relax the parts & are injurious Change the nurse also if necessary If the child is fed upon milk by hand, add perhaps a little magnesia or lime water Similar affections may affect the cavity of the ear & the cavity of the nose. If the cavity of the ear is affected in this way & neglected ulceration is apt to take place & the small bones affected causing deafness. First reject milk & water or carb. soda etc. [illegible] Finally if these means fail use stimulating injections myrrh finally [vit.] sil. In the use of [illegible] sil. external began with 5 grs to the oz & increase if necessary to xv or xx to the oz 31 of the evacuation, as is generally said, but of the habitual action of the system. This affection sometimes degenerates into a very troublesome ulcer, extending down the neck, accompanied with much pain & yielding a discharge so acrid as to excoriate the skin wherever it touches it Deep sores will be formed & the affection may terminate in gangrene & death In such cases it may be proper to apply emollient poultices of bread & milk; to which may be added poppy leaves, or pulverized stramonium seeds or ac. plum. Powdered gypsum is one of the best applications Alabaster gypsum is the finest kind Some apply red precipitate but gypsum is far better. Case in which this alone cured; Another physician advised red precipitate The oxygenated ointment if well made is a smooth dressing for them & is the best kind of ointment, where ointments do not disagree, as it sometimes the case. The bowels should be kept open with cal. or blue pill. It will sometimes be necessary to correct the milk of the nurse by administering magnesia & confining her to a simple diet Troublesome & sometimes fetid discharges on the internal surface from the ear arising from a kind of eruption may follow this eruption & may cause deafness if neglected I have known also the cavity of the nostrils & the frontal sinuses affected in the same manner. A cure may be affected in either case by exciting the discharge behind the ear though it may be necessary to keep it open for some time If this fails use (in addition?) milk & water Milk 2 part water 2 part lime water 1 part Tinct. of myrrh if the discharge is fetid & troublesome a teaspoonful to a gill, as an injection for the ear Sol. nit. sil. 1 or 2 gr to oz. water? externally Be very careful in watching the symptom Case of a young man who had had such a discharge for years checked by astringents [delirius] inflammatory fever ertc. bled cathartics etc. Porrigo galeata ([helvetea]) Cuticles below the scales dotted, shining Said to be contagious. I have never happened to see it so though I do not doubt the fact. I have never seen more than one in a family have it A very troublesome complaint The hair becomes pale, perhaps the roots are affected in which case mercury is indicated. Salivation seems to do no good I have seen it practised without any benefit Recent cases I have cured very speedily with oxyg. ointment. Any smooth substance applied to the part & excluding the air, will often cure as for in stance a bladder, or the membrane of suet what is useful also for [fret] Poultices do well, whether upon this principle or moisture changing secretion When a student I recollect there appeared a strong recommendation of poultices A physician of my acquaintance prescribed a poultice & left his patient. It adhered the hair grew into it and the hard crust formed a helmet indeed. It [was] a long time a period of week, before it was removed When it came off however, the disease was removed! 32 Tinea Capitis. Scald Head porrigo This is a local affection & yet much influenced by diet. Sometimes however it affects the system, or is sympathetic of a general affection of the system. The disease consists of scaly eruptions, eventually covering the head with a hard & generally brownish coloured crust. The hair often comes off. Cleanliness holds of course the first place in the list of remedies; the head should be carefully shaved and washed repeatedly with soap and water. Perhaps as successful a mode of treatment as any will be to shave the head closely and apply a bladder or affect skin in close contact with the skin. It excludes the air. Sulphuret of potash zfs or ai to a porter bottle used as a wash & given internally tablespoonful 3 times a day has cured the complaint in a few days mercurials or corrosive sublimate will be useful, but do not always cure. Sulph. prt. internally zii to lb i [illegible] ext zii to lb is [illegible] The ueast poultice is good, but care should be taken that it do not become dry on the head, which should be first shaved. The oxygenated and the citrine ointments have been found useful, as had also the tar ointment which is made as follows Rx tar ziv wax zfs sulphur zi or is Mercurial cathartics should be given from the first and particular attention paid to the diet. # vide last par. The practice in this complaint has been quite empirical & a great variety of remedies, have been popular. Veratrum viride & v. albus & [apocynum] [androsaem??] olium have used for external washes. Syrup of buckthorn is recommended as a cathartic. Muriatic acid Lunar caustic about 6 grs. to zi of water (rain water) well water may decompose it Decoction of cocculus indica, is given internally & externally. Cal. zii al burnt zfs red lead zfs z6 zifs spermaceti cerate head shaved & washed with soap sude every night and afterwards apply this ointment. It is given by [illegible] & Bates [illegible] & called Diet must be attended to Terebinthinate ointment as tar ointment Tar ointment is made of tar and lard or tar & simple cerate There is no difficulty in the diagnosis of the disease. You will be called to prescribe for scalled head and you will find that the nurses have not mistaken the disease. It begins with small pustules the matter [illegible] which is acrid and soon forms a scab over the whole head. The treatment must be principally local. But mercury may be given occasionally. I have not derived much benefit from the common mercurial ointment. Citrine ointment is good however. Also cal zif lard zi 33 has been used 3 or 4 drops in a wine glass of water Finally the sorts of the various species of dock (rumex patientia, crispa obtusifolia, sanguinea, aquatica etc.) have been much used All the species have about the same properties, being acrid purgative etc. They are given internally as cathartics, & externally applied, made for instance into an ointment, by pounding up the fresh root with lard. The following is a recipe Rx yellow resin zii best ale lb i finest flour ziii mix the all & flour thoroughly together & add them gradually to the melted resin. # The tepid bath may be used when this is used always take care to have a supply both of hot and cold water in order to keep up the proper temperature. Ipecac may be administered to equalize excitement in some cases, & as a valuable substitute for this article we can use the root of asclepia, tuberosa, which is expectorant, diaphoretic and laxative. “Vary the remedies according to their affect soften use decoct. rumex particularly r. obtusifol. called horse dock. It at firs increase, the irritation & secretion. Use it externally & internally” The excitement of the al. can. is affected also of the nervous system Various cutaneous aff. different kinds also of local inflammation, or erysipelatous phlegmous gangrenous scrofulous the inflammation varying according to the constitution scrofulous gangrenous I have frequently heard Pres. Dwight speak of the pain he experienced in cutting his wisdom teeth suffered extreme pain for a whole summer She did not appear to me to look like a person in the consumption I was puzzled [illegible] [illegible] I looked into her throat and mouth and found she was cutting r wisdom teeth # The irritation may continue for mouths, from the pressure upon the gum Those who commence cutting teeth at 10 mo. to a year or even later do not necessarily suffer more Delicate & scrofulous children suffer more 34 Dentition Among the causes of infantile diseases no one more claims the attention of the physician than dentition. The bowels and the nervous system are always more or less affected by it & to this cause we are frequently to refer affections of the lungs of the brain, of the ear, of the skin, of the glands, & of the cellular tissue in general. On this subject there is however a difference of opinion, for it is said by many medical men that children which are healthy # well teeth with as much ease as adults. Allowing for the peculiar irritability of [illegible], no doubt they do, but in granting this we concede nothing, for adults often suffer extremely from dentition. I well recollect the case of a Mrs Waters perhaps about 20 or 21 a married woman and the mother of said to have a [illegible] several children, who was supposed to be in the last stage a good deal of cough etc. had raised a little blood on consumption & upon examination & found was cutting the four wisdom teeth. The gums were divided & antispasmodics administered, when she recovered perfectly. # Case of Mrs Purcell’s child had been sick with diarrhoea and fever for some time a flush of fever coming on every day. I had previously extracted defective teeth from the [illegible] mouth. I now looked into the mouth lanced the gum over a double tooth gave no remedies The period of dentition commences at different ages times in different children, varying from the fourth to the sixteenth mouth, but most commonly in the sixth. The two central incisors of the lower jaw appear about the sixth month and are followed in about a month or six weeks by the corresponding teeth of the upper jaw. very [illegible] [illegible] [illegible] cases I have known a double tooth cut first in others an eye tooth in others all the teeth at once You must always examine to see what teeth are cutting You will perceive the gum swollen and harder Some children are born with teeth but such teeth re merely attached to the gum and are useless and should be removed Sometimes there is too much anxiety about dentition generally however not enough Case of a child mother called me insisted upon # irregular distributions of temperature are [illegible] [illegible] hot 5 [illegible] cold 35 Next come the inferior lateral incisors & after these the corresponding teeth above About the twelfth or fifteenth or 20th month appear the anterior molares & are soon succeeded by the cuspidati those of each kind in the lower jaw cutting through before those in the upper. Next we have the posterior molares. The last molar teeth are not found in the child & hence their name, dentis sapientiae. They appear from the 18th to the 25th year. The above is the order in which the teeth commonly appear, but they often come irregularly, sometimes the lateral incisores, sometimes the molares, & in a few rare instances the cuspidati appearing [illegible] Some persons never have more than two incisores in each jaw Occasionally we meet with families who are said to be destitute of teeth. I have known a family from Charleston, who had this peculiarity. The fact however is in such cases that the teeth exist but not rise above the level of the gums, so that they are not ordinarily seen Such teeth have this advantage, that they are not subject to decay & are also very serviceable. Whenever between the fourth and the eighth 2nd year? month symptoms of irritation exist, the cause of which is not obvious, the state of the teeth must be examined. The symptoms of difficult dentition are fretfulness inclination to bit hard substances, putting the fingers into the mouth, slavering, starting in sleep eruptions about the face & on the scalp, flushings in the cheeks. # hot head pupils contracted sometimes dilated sometimes losing their brilliancy In delicate children the eff. will be more chronic & in vigorous more acute The system relieves itself often by evacuation and this is considered often a good symptom as [illegible] there is a great flow of saliva. The system relieves itself by diarrh. by salivation by sweating [illegible] by every mode of equalizing excitement which is the great principles on fevers & indeed in most diseases 36 and cold feet, irregular paroxysms of fever, remitting fever vomiting diarrhoea irregular & green stools wine small in quantity & voided with pain or in large quantities and of a pale colour bloating of the hand feet and face contracted pupils. All the symptoms indeed of extreme irritation may be met with & we likewise find in many cases a tendency to phlegmonous inflammation suppuration in various parts of the body particularly in the ear. Case of a child who was thought to have an affection of the brain. A tumour was found under the arm. Sometimes dentition is accompanied with phlegmonous local inflammations in different parts of the body & suppuration of the glands about the ar by which relief is afforded Ricketty children cut their teeth more slowly than others but not in general with greater difficulty. The child must be held, and the fingers keep in the mouth to keep it off the tongue # The guard being made with a spring, so that when pressed upon the guard will yield and permit the lancet to descend (in the slit of the guard) 37 Treatment. The first and most important indication is to divide the gums with a gum lancet or other convenient instrument. The operation is not usually painful the child will even press against the edge of the lancet. The relief is often immediate and permanent Some relief may indeed be afforded by rubbing the gums with a hard & polised substance & by giving the child something of the same kind to bit, but the most effectual relief will be afforded by the lancet. The chief difficulty in the performance of the operation consists in confining the child. It may be done while the child is asleep & often without waking it. We must also be cautious not to cut the tongue To prevent this it would be better to make gum lancets with a guard # For the double teeth two incisors should be made & it may be necessary to make a transverse one in order to divide a band of a sort of ligamentory substance which confines the tooth. It is sometimes objected to cutting the gums in particular instances that, if it is done too early, the cicatrix formed by the healing of the incision will subsequently render it more difficult for the teeth to push themselves through This is not true for the cicatrix though apparently harder [illegible] less vitality in it than a part which has not been wounded and will be more easily broken through Solution of continuity is more easily made by disease in a cicatrix than in a part which has not been wounded vide J. Hunger. It is a common maxim that an old scar is apt to break out in to a sore The gums should be divided as often as there are any symptoms of irritation, until the teeth Some other diseased action may exist in the system, and the irritation of the teeth be superadded the lancing will only relieve the latter # For the gums having been exposed for a long time to irritation because [illegible], and perhaps ulcerated and are kept irritated by contact with the hard tooth 38 get through I have repeated the operation three or four times upon the same teeth. In some cases however cutting the gums relieves the symptoms only in part. Indeed the irritation sometimes continues after the teeth get through # “use astringents” If any disease from the causes attacks the child during the period of dentition it will be very important to remove all irritation from the latter source, for otherwise all the symptoms may be aggravated & a disease be rendered mortal which would otherwise have been mild. In children of a vigorous constitution dentition is often accompanied with inflammatory symptoms which require an antiphlogistic plan of treatment. Lancing the gums will then be useful as local bleeding & it may even be advisable to bleed from the arm though a few leeches behind the ear are preferable. It must not be forgotten that in infants, the bowels afford a great outlet to diseased action and to irritation: hence the frequent occurrence of a spontaneous diarrhoea. If the patient is costive or if it has a diarrhoea, a dose of calomel should be administered & if the bowels are soluble a milder mercurial, as blue pill may be given. During the whole period of dentition the bowels should be kept open by such cathartics as the state of the system may indicate, such as magnesia, rhubarb etc. adding aromatics if the system is relaxed and debilitated & chalk if there is acidity If a diarrhoea suddenly stops and vomiting supervenes, externally irritant to the [illegible] [surface] generally, injections, calomel The skin shd be kept moist for diaphoresis is one of the most powerful means of equalising excitement etc. If there is much perspiration you may depend upon op. alone but whenever there is much [unequal] excitement opium alone will not do well and ipecac shd be combined with it in small doses # Also by drafts to the [illegible], by local irritants to the skin generally also keep the bowels from remembering that there is no outlet to the brain 39 and the warm bath are to be used, as has already been mentioned under the head of diarrhoea Another & a powerful mode of equalizing excitement & relieving irritation is by diaphoresis. For this use the warm bath & small doses of ipecac & opium or of antimony and opium. Opium will always be useful to allay irritation & particularly if combined with ipecac or antimony, & always safe when there is no determination to the head Small blisters behind the ears relieve the symptoms of dentition & prevent the disease from terminating in hydrocephalus. # If these cannot be kept behind the ears mercurial ointment or cantharides may be applied to the same part. Nervines may be employed either with our without ipecac During dentition exposure to dampness & to currents of air should be carefully avoided & the patient should be kept warm X summer & autumnal epidemic Indeed the effects of it sometimes continue through the winter The desire often resembles spasmodic cholera in the premonitory diarrhoea & the sudden collapse 40 Cholera Infantum This disease appears in New Haven in the month of July August September & October. It rarely commences until the latter part of July & in October there are few cases except those which have commenced in one [illegible] other mouths & continued until this. Indeed cases are sometimes prolonged till the middle of November Symptoms. It begins in various ways; most commonly with diarrhoea, which may continue for days & even weeks without any very alarming symptoms; At other times times with violent vomiting & purging accompanied with high fever. The discharges from the bowels very much in their usually [illegible] from natural colour [illegible] [irritated] [secretion] appearance. Sometimes they are yellow, brown or green, sometimes in small quantities & slimy and bloody & at others in large quantities & watery, smelling like water in which putrid meat has been washed. Worms likewise may be found in all these various sorts of discharges “dead in the advanced stages” The disease is usually accompanied with great restlessness & often with severe pain, which increases by paroxysms at intervals of from fifteen minutes to two hours The pulse is usually quick and weak, the head hot and the extremities cold. The fever is ordinarily remittent but the exacerbations are frequently quite irregular The disease is attended with thirst often [illegible] and after drinking the child vomits. The eyes often appear languid and hollow During the whole progress of the disease [volvulus] may occur Be on the look out for it “The termination of this disease in hydrocephalus I have reason to think is more rare than is commonly supposed. Many cases of this kind occurring in my practice, I have reason to believe were cases of volvulus Or varying from cholera morbus of [illegible] [remittent] bilious fever sometimes putting in the form of cholera of [illegible] at others that of remittent bilious fever 41 while in other cases they may have an unnatural brightness as in pulmonary consumption indication a high degree of mental [illegible] excitement “of bad symptoms” Sometimes the eyes are half open during sleep, as is indeed the case in various bowel complaints of children when severe we often find the diseased action translated from the bowels to the head and terminating in hydrocephalus. Volvulus also may be another termination. Sometimes the vomiting ceases for several days and then returns, while the diarrhoea continues the whole time Duration As to the duration of the disease, it may be very rapid in its progress & terminate fatally in forty eight hours, or continue for months, & the symptoms may vary very much during the progress of the complaint. A damp hot atmosphere will aggravate all the symptoms, while cool weather with the wind from the northwest will mitigate them. In different seasons also cholera infantum will have symptoms peculiar to the year, varying in this respect like other epidemics Finally when it proves mortal, the child is carried off in convulsions, or is worm out with emaciation & dies with aphthae while in some cases death is ushered in by hydrocephalus, volvulus & other diseases Causes. We may consider the cholera infantum as an epidemic sometimes an endemic confined to a particular season of the year analogous (in its grade of action) to the cholera morbus o f adult “This disease is perhaps most analogous to a remittent bilious fever varied by the peculiarities of the [illegible] [illegible] will see in [Jackson] all that can be said in [favour] of the opinion. The very fact that it is often [illlegible] disproves the opinion besides the fact that the disease does not occur at all seasons during the period of dentition The disease is affected by the state of the atmosphere being much aggravated by a damp state of the air always minded by a cool bracing northeast wind The kind and gentle excitement produced by nursing is important in chronic disease “Children should not be weaned till dentition is complete or till 1 ½ years & in the fall” 42 infantile constitution” Dentition has been considered by some as the cause of cholera infantum but to this opinion I cannot assent thought it is held by Dr Jackson & many of our most respectable physicians Dentition may indeed be an exciting cause; it often aggravates all the symptoms & accelerates the fatal termination yet in the winter spring & months it does not produce the disease of not unfrequently children are affected with cholera infantum without any appearance of dentition Worms sometimes make their appearance during the progress of the disease but they cannot be considered as a [illegible] or cause of it. When they exist during the complaint the irritation which they produce must be obviated by such anthelmintics as are not contraindicated by the state of the system. “I think I have seen the [illegible] productive of unfavorable effects.” The cholera infantum probably arises from the same remote causes as the (cholera morbus) & the bilious remitting fever of adults such as damp hot confined air (which can be counteracted only by exercise in the open air) want of cleanliness & bad diet. Improper food may be both a remote & an exciting cause & the same is true of a bad state of the atmosphere muggy or [illegible] of inequality of temperature & exposure to cold. The predisposing cause produced by these remote ones is debility Children weaned in the spring are mor apt to have this complaint, & do not bear the disease so well as those at the breast. I would therefore advise that in places where cholera infantum prevalent. children should be weaned in the fall 43 Some consider malaria the cause Like dysentery this is a disease translated from the surface to the first passages. The fever is of that kind which Sydenham calls febris introversa the action being of an irritated kind in general & rarely of an inflammatory Commencing at the skin & breaking up the balance of the system by obstructing the perspiration the morbid action is transferred to the mucous membrane of the intestines & involves the liver, pancreas & all the glands immediately sympathizing with them. Indications. The indications are 1st To evacuate the first passages; if this has not been already done by the disease itself 2ndly To translate action to the surface & in general to equalize excitement 3dly To excite healthy secretory action and regular peristaltic motion of the bowels 4thly To avoid the causes of irritation and to remove irritation when it exists 5thly To restore the tone of the system & particularly of the stomach and bowels 1st When the disease comes on like the cholera morbus of adults, the stomach and bowels are sufficiently evaluated by the disease generally when the phys. is called and no evacuation s are to be used. It is to be treated like cholera morbus with aromatics as essence of peppermint, with Laudanum We must be careful not to prescribe for the [name] of the disease nor necessarily pursue the plan of treatment generally proper. Often you will find the patient so much debilitated at first as to require stimulants & acrids When we have the collapse stage and a collapse may recur in any disease then the practice of the nurses is correct in acting on the skin Some recommend large doses of cal. [illegible] much smaller the [common] Dr Jackson recommends large doses common in the commencement. Dr [illegible], 1 gr. doses and salt & water I recommend cal. from 1 to 10 gr Though sometimes small doses repeated may change the secretion better than large, yet often a large dose will operate more kindly, then a small one [which] merely irritates “Dr Dewers recommends injections of salt & water 2 or 3 teaspoonfuls to a gill, instead of cathartics. Repeat the injections till full catharsis is produced the morbid action is changed, by translation of excitement from the stomach & small intestines [illegible] [illegible] with cal. ¼ gr. every [illegible] to alter secretion 44 with counterirritants, as mustard, horseradish & brandy on the epigastrium & abdomen with the tepid bath & with injections of starch and laudanum. But when it attacks with a diarrhoea, accompanied with occasional vomiting unless the constitution is very feeble constitution [illegible] extremely delicate the stomach should be evacuated by ipecac and the bowels by calomel or blue pill To vigorous patients & often give in the commencement six grains & would not hesitate to give 10 grs of calomel & an hour after give from one to ten grains of ipecac according to the age and vigour of the patient for in this way the stomach and bowels are more thoroughly evacuated than by giving the calomel after the ipecac has ceased to operate In some cases a single dose of calomel will thoroughly evacuate the bowels, but in others it will only remove the contents of the stomach and small intestines into the colon & a dose of castor oil must be given or one of senna with aromatic seeds The southern physicians, make less use of cathartics and depend much upon stimulating injection, as of salt & water 3 teaspoonfuls to a gill. This practice does not succeed well with us. They also give smaller doses of calomel. This also I cannot approve for a large dose of calomel, ten grains for instance, will evacuate the bowels copiously and kindly, when small ones produce scanty stools, with irritation of the stomach and tenesmus. I may mention also that the French expectant plan of treatment adopted in Philadelphia will frequently be utterly inefficient. Where excited has not been equalized, calomel or any other cathartic may act upon the duodenum only and not produce Such facts as there have been given rise to the opinion that the disease arises from stricture but then the al. can. may be subject to unequal action as much as the skin # a castor oil with elix. sal. aa zi every 2 hours # Yet this practice shd not be adopted indiscriminately where there is weak morbid action accompanied with coldness of [surface] etc. the exhaustion of cathartics will be injurious This is the most important principle in the cure of diseases Sometimes cath. cure the diarrhoea, where the action is unequal. For instance the lower intestines may be torpid and the feces accumulate, the bowels above may be irritated and a diarrhoea of [small] liquid stools may pass by the feces 45 If calomel or any other cathartic produces watery stools in which are small pieces of feces of an ordinary appearance, and there have not previously been copious evacuations, we may conclude that a thorough evacuation of the bowels has been prevented by a spasmodic action of the intestines which has constricted them in places, & confined, perhaps a large quantity of fecal matter. Indeed this may be proved by the success of the treatment, which should be the administration of a dose of opium with a little calomel to change action followed at an interval of one or two hours by a dose of z ¼ and z ½ castor oil or elixir salutis teaspoonful #. It is of the first importance in all typhoid diseases, particularly in those affecting the bowels, that thorough evacuations should be made # 2ndly so translate action to the surface and equalize excitement This indication will be answered by an emetic at the commencement, as already directed & by small doses of ipecac, repeated throughout the disease, & also by small doses of mercurial medicines opium being conjoined in many cases, as will hereafter be mentioned. In some calls where there is much arterial action antimony is preferable to ipecac & the lancet or leeches may be indicated but such cases are rare This indication is also answered by applications to the abdomen of fomentations, with decoctions of aromatic herbs sinapisms, blisters, burdock leaves, horse radish leaves, ginger in spirits aq; amm or the Ulceration of the bowels is generally preceded by aphthae both are effects not causes of the disease “An [epispastic] should not be applied after aphthae have made their appearance. If the pat. is languid & sleepy we may suspect aphthae.” Diluents may be used Obviating irritation by opium is often necessary to have the proper effect of cal. for instance Give opium first & follow with cal. & often you will succeed in obtaining the effect of the cal. when you had failed before “Ipecac when it acts as a cathartic is more apt to produce fecal stools than any other article 46 terebinthinate oils An epispastic upon the epigastrium is very useful to relieve irritation of the stomach & to prevent ulceration of the bowels and aphthae. The warm bath will tend powerfully to equalize excitement will relieve vomiting, quiet restlessness, produce a uniform perspiration & if used at evening, procure a quiet nights’ rest. It may always be used and at any time, unless the patient is in a state of exhaustion. As a substitute for ipecac, the root of the asclepias tuberosa may be used. It is much used in infantile diseases as diluent, to determine to the surface & to promote expectoration. 3dly For changing the secretion of the stomach and bowels and keeping up a gentle peristaltic motion I have found small doses of mercurial cathartics with ipecac of opium superior to all other remedies. If any article deserves the name of a specific in any disease, it is ipecac judiciously administered in cholera infantum. It relieves this disease with more certainty as certainly as than cinchona does intermittents. It may be observed however that a man successful with one remedy only m ay be compared to a mechanic, very skillful with a pen knife! My method of administering the articles is the following. For a child four months old, mix 4 gr. of ipecac & 5 drops of laudanum in twelve teaspoonfuls of water & give a teaspoonful every fourth or fifth hour & at the same time give so much of the blue pill as to You will know when the blue pill begins to have its appropriate effect by the change in the color of the stools Pills of blue pill may be given without much difficulty to children there is little taste except of the saccharine matter. They may be given in food [illegible] dried huckleberries which I have often called for in the country where there was difficulty in administering remedies. There is often great difficulty with respect to this. A child will often scream at the sight of the doctor Opium to allay the irritation of the stomach and prevent the ipecac from being thrown of Ipecac to equalize excitement & determine to the surface Ipecac also, to qualify the opium # Or if this cannot be done, introduce a paste of opium just within the sphincter # Case of a child in a family where 3 or 4 children had previously died of chil. inf. [Lax] & [illegible] habit etc. I commenced the treatment with the pill and ipecac I treated it mildly giving blue pill instead of calomel N.B. For such cases [illegible] 47 procure an evacuation from the bowels two or three times in [never twice] in the twenty four hours. For a child a year old take twice as much ipecac & laudanum with the same quantity of water and give it in the same way. Sometimes three times the quantity of laud. will be necessary; for instance if the child has been in the habit of taking it or if the diarrhoea is very urgent If the diarrhoea is urgent, it may be necessary to administer injections of starch and laudanum & to apply to the abdomen ginger & grandy volatile liniment poultices or other irritants The enema may be made with three table spoonfuls of flour & about 3 or 4 times as much laudanum as you give by the mouth say 10, 15, or 20 drops. # I prefer flour to starch because the foreign starch often contains acid. The chalk mixture or white decoction may also be used. # “Children of a bucophlegmatic temperament and lax habit are very apt to have this disease & with them I have sometimes commenced the treatment by administering blue pill & ipecac.” The success of this plan of treatment will be strikingly shown by the following case. A child 10 months old was taken sick in this town last summer, with cholera infantum, grew worse and was directed by the physicians to be carried into the country Unfortunately the child was carried to a situation not more elevated than N. Haven & while there its strength decayed and all its symptoms were aggravated. The parents despairing of it recovery returned with it to N. Haven & sent for me with a request that I would do something to alleviate its sufferings On recovery from the disease they usually crave [salt] food and salt is a grateful stimulus 48 I found it in a state of emaciation, with hippocratic countenance frequent vomiting, urgent diarrhoea, with stools fetid, watery and containing some slime and mucus, & leaving streaks of blood upon the cloths. The countenance and gestures, expression of great anxiety, and there were frequent paroxysms of extreme distress. I directed ipecac 5 gr. & laud. 10 drops to be put in 10 teaspoonfuls of water and a teaspoonful to be given once in four hours flannel wet with ginger and brandy to be applied to the bowels & gave 5 oz. blue pill, & ordered the diet to be of arrow root flavored with a little brandy. After the second dose the vomiting stopped, the stools became less frequent & within 24 hours the complexion of the stools was much improved. The next day the same medicines were continued and four drops of the tonic solution with a little brandy and water. On the fourth day from my first visit, the child began to relish salt fish, which was allowed Capt. Dennison’s children To correct fetor in the stools we should give charcoal. Carbonic acid, by injection, is given for the same purpose. The mode of injecting carbonic acid, is to place chalk & vinegar in a bladder, and force the gas into the rectum, as it evolved. “This is recommended. I have tried it but not very thoroughly” But if vegetable food undergoes the acetous fermentation it shd not be used. The putrefactive fermentation however is more injurious than the acetous 49 4thly The most common cause of irritation is dentition The gums should be often examined, & be divided if they appear at all swollen. All kinds of food that is hard of digestion should be carefully avoided though for children somewhat advanced perhaps a small quantity of ripe fruit may not be injurious If the child has not been weaned the milk of the mother will be the best food; for those children’ who nurse are more apt to recover than those that have been just weaned. The act of sucking is highly soothing and gratifying & operates like a nervine medicine. The best food for children that have been weaned, will be arrow root, with a little brandy or wine as a condiment & as a substitute for this & similar articles from the shots, we can direct a porridge made of roasted flour. If in the latter stages of the disease the child craves any particular of food, as salt fish, or salt meat, or wine or brandy, it should be given, & all kinds of medicine laid aside if the stomach leathe3s them; for strong disgust will debilitate by exciting nausea. Frequently however we can succeed in preventing this effect, by a different mode of administering the medecine the sight of the spoon for instance may may give rise to the loathing & nausea. With respect to food we may lay it down as a general rule in such cases that when the powers of the stomach are so weak that food must undergo fermentation in it, vegetable diet should be preferred to animal. For local irritations, various applications should be made & various articles administered, especially in the latter stages “Tea juice? boiled beef a teaspoonful with pepper & salt is grateful frequently & checks vomiting but at first vegetable preparations are better” vide supra The chalk mixture made with a little opium in some cases or with astringents etc. a valuable [illegible] 50 of the disease or when we are compelled to try a variety of remedies. When there is unequal excitement & unequal temperature blisters may be used. Blisters sometimes produce perspiration. To relieve irritation of the stomach effervescing mixtures may be drunk, they are often more grateful. [illegible] we may fill the stomach where there is vomiting and dilute its contents with a tumbler of wine whey I have often succeeded with it with a teaspoonful of aqua ammoniae in it as being thrown up will be no objection. If the disease commences with much irritation in the stomach, it may be useful to overcome it by counterirritation in the rectum produced by an injection of soap suds or of salt and water 3 teaspoonfuls of salt to a gill of water, for a child a year old. Dr Dewers relies must upon this latter article in the commencement of cholera infantum and repeats the injections until the bowels are fully evacuated. He likewise recommends small doses of calomel, a quarter of a grain for instance repeated once in an hour until the bowels are evacuated. In cases of irritation of the stomach & torpor of the liver & portal system, this practice of salt & water & small dose of calomel does well. In chronic cases he gives magnesia rhubarb & opium. With respect to small doses of calomel it may be further observed that they will not answer when the intestines are much coated with mucus & that in some localities they do not answer so well as in other places. On the shores of lake Erie for instance the physicians are obliged to give large doses of calomel than we give There are cases in which small doses seem to irritate & large doses operate kindly “In the latter stages Rx magnesia grs 4 SS gtts Rhei gr i.” C. Florida not so pleasant but loses its mawkish & herbaceous taste by keeping (like peruvian bark) The spiraea is though less inclined to act unequally in this state than most other astringents If one astringent wears out try another Oak barks Rose [illegible] (salix [illegible} “A valuable popular remedy” has mucilage combined seeming to resemble ([illegible]) [illegible] was formerly much used but is now superseded by native articles It is well known that because These astringents are often prompt up is specific [illegible] virginica was specified good [illegible] & [illegible] it e.g. viburn. lentigo, raspberry, blackberry, [illegible] [illegible] root decoction recommended by Dr Rush thought to deter to [illegible] used by many) [illegible] bark has [mucilage] There is apt to be a paucity of [urine] in this disease as well as in Diarrhoea & dysentery and then diuretics are indicated and are highly valuable 51 5th When in the latter stages of the disease the principal indication is to restore the tone of the system & particularly of the stomach and bowels we must make free use of tonic and astringents. Moseley’s tonic solution will be one of the safest and best articles in this stage. If the bowels, by a habitual action keep up the diarrhoea, astringent will be more specially indicated such as the compound tincture of vitriol. I prefer however, the cornus circinata to all other articles C. servicea (red [illegible]) C. [illegible] C. alba nearly allied Of astringent vegetables we can make choice from a great variety which are indigenous & common. All the various species of viburnum all the [potentillas] & the roots of the strawberry to say nothing of the bark of the oak & indeed most of our forest trees, are astringent & may be used The spiraea tomentosa is much used in decoction or extract All the species of [illegible] are astringent & the C. [rivale] is a most valuable article; as is also the geranium maculatum, which may be be given in wine & then we shall have red wine. The sttici limonium (marsh rosemary) is not so agreeable but is frequently more efficacious specially if the mouth is sore. Its taste resembles that of salt mud. When given internally, it is boiled sweetened & has a little wine or brandy added. It is also used as a wash in case of the supervention of aphthae. The erigeron canadense, called colt’s tail & strangury weed has been found a valuable article in the latter stage of this complaint and of dysentery given in decoction. It is acrid pungent like [illegible] bitter & stimulating & acts also upon the kidneys as a diuretic. It seems likely to prove a Give it in decoction or in milk which will cover the taste of it Balsam of copaiba or turpentine cannot be combined with mucilage so thoroughly as in the white pine bark in milk & water diuretic & [sheathing] to the bowels I have often used the expressed juice of spearmint as in diarrhoea q.v. It is important in long continued bowel complaints of children that the medicine shd be grateful The diuretics are useful both in children and adults (dysentery diarrhoea & cholera infant) because there is a paucity of urine and acrid irritating secretions In some cases of exhaustion we give opium constantly in small quantities to keep up the [illegible] Mucilages marshmallows or substitutes for which hibiscus palustris hib. syrica hib. [illegible] hib. (rose of [shora]) Mucilages by stopping irritation are diuretic 52 a valuable article in the latter stages of bowel complaints provided there is not too much vascular action. It has been long used, vide Barton, the N.Y. Medicophys. Transactions etc. In 1790 an itinerant came through N. Haven offering to cure the dysentery; and attracted a good deal of notice. It was found that his [illegible] consisted of this article. The other species of erigeron have similar properties. In the latter stages of the diarrhoea mucilages should be given. They made of any of the various in articles in use, but perhaps the most valuable mucilage, will be that made from the inner bark of the white pine, which will furnish a terebinthinate principle in addition to its mucilage Often in the latter stages of the disease, great benefit will result from supporting the abdomen by a bandage and a plaister of white [diachylon] and opium or a soap plaister (of [illegible] & soap) 2 parts sp. 4 pts plaister In extreme exhaustion & debility from the long continuance of the complaint with cold extremities, aromatics and stimulants may be required & we may give spiced tea spiced wine or brandy in small quantities, or the white decoction and apply cloths dipped in brandy to the abdomen & to the extremities Nothing has more affect upon complaints of the stomach liver & bowels than the state of the mind as we see in dyspeptics The We are apt to suppose children not subject to notice of [illegible] children [illegible] mental impressions. When the matter has been dissolved in grief & abandoned to despair I told them to tray as a last resort carrying the child in a hack out of town the excitability was entirely gone the child might as well die in the back as any where strange advice On the top of the [illegible] about two miles out lifted up the child [sound] trees grass birds, etc. opened its eyes before this had lain with eyes half closed noticing nothing 53 Finally when every form of medication seems to fail, our only remaining resource will be change of air. This is a most powerful remedy. The physicians of N. York and Philadelphia are continually recommending it. We are apt to suppose that in children it can be only the purer air & the exercise of travelling that produces a good effect, when they are carried from home for their health, but on the contrary the change of scene seems often to have a more powerful effect upon them than it would upon adults. Children that have lain sick for weeks, instead of pursuing their accustomed amusement even though mere infants seem of ten to settle into a state of utter despondency from long confinement & the constant sight of the same unvarying objects around them, & appear to loath every thing offered to be done for them. This morbid condition of mind seems to be one directly opposite to that of nostalgia or homesickness & is to be relieved in a corresponding manner. I well recollect a child apparently in articulo mortis cold & vomiting nothing wd [illegible] the vomiting entirely beyond the influence of medicine or food. It was carried in a hack to the top of a hill without the town N.Y. [illegible] where it had a view of the sound, & the scenery of the country around. While there is brightened up vomiting ceased and took food staid an hour or more & then was carried back to town, where it finally recoverd. 54 The symptoms attending cholera infantum very very much and give rise to considerable variety of practice It is probably owing principally to this circumstance more than to any other that physicians differ from each other in their mode of treating it. Post mortem examination show that this disease affects principally the mucous membrane of the stomach & the small intestines; rarely the large ones. Sometimes coagulable lymph is found in the intestines but less frequently than in other diseases. Sometimes the mucous membrane of the intestines is thickening & according to Dr Jackson ulcers are occasionally found both in the small & also in the large intestines. The liver is usually enlarged without derangement of structure Ordinarily the brain exhibits no morbid appearances, unless the disease has made a determination to that part constituting hydrocephalus N.B. The remarks upon asclepias tuberosa introduced under the Head of [illegible] capitis probably belonged here Fever of the bowels Acute [illegible] of [illegible] Different writers give different names and do not always give the same symptoms. The European disease differs somewhat from ours. It is our infantile winter epidemic. Typhus infantum of Prof. [Tully] “Disease of the bowels bowel complaint, plague of the bowels, winter epidemic & [illegible] epidemic. Remittent bilious fever (at south) Musgrave’s spurious [illegible] fever Duncan III or IV” There is some [illegible] action but more of the character of irritation like other infantile fevers Rarely vomiting never diarrhoea in commencement The morbid excitement often extends to the lungs putting on the for [illegible] what is called in adults bilious pleurisy The disease is not common at this time though it was very much so formerly Probably it will return It is almost the only winter infantile disease & so common has it been also that the nurses call almost every disease in winter, of childr, by this name of choler. The dis. is to be broken up in its [illegible] by means various in various patients by a strong impression upon the stomach in a strong constitution but by an impression upon the whole system in the delicate constitution Comparison to a weight upon a [illegible] If applied upon one part only it will break it not if applied to [illegible] It is desirable that vomiting or at least nausea should talk place from the cal. In enteric 55 Constipation with Fever or Remittent bilious fever of children Musgrave’s spurious worm fever marasmus acutis This complaint has been known in N. Haven for more than 50 years by the name of choler. It is called in some places at the “It is unfortunate that we have no better [illegible]” eastward, the plague in the bowels. It is a common bilious “It affects however the duodenum & small intestines rather than the liver” fever produced by causes which operate upon the bowels a part of the system which in children more particularly invites Children are attacked by it from the age of 3 mo. to 2 or 3 yrs. febrile action. It is often inflammatory in its commencement Sometimes it [illegible] in the form of typhus Symptoms The pulse in the commencement of the disease is full, frequent & sometimes tense, the skin is hot and dry face flushed, respiration, short and laborious, tongue covered with a white fur, the abdomen fuller and harder, than in health, & the bowels costive; the urine small in quantity and high coloured & sometimes the fever is attended with cough & expectoration. This disease is a fever which often affects the lungs and always the alimentary canal & liver, the secretions being suspended and the bowels constipated. Treatment. This will be antiphlogistic in the commencement of the fever & the first indication will be to evacuate thoroughly the stomach and bowels. This will best be answered by a single dose of calomel of from 5 to 10 or 15 or even 20 grains for a child from four to twelve months old We shall thus produce a strong impression upon the whole alimentary canal & upon the system at large. In entonic cases and vigorous habits a little tartar emetic may be added to the calomel Usually the calomel excites both vomiting and purging, but sometimes it is retained on the stomach and has no immediate cases it may be beat to conjoin tartar emetic for this purpose. Sometimes the cal acts upon the stomach & duodenum & excites the action of the liver, and spends itself there, without producing catharsis Sometimes it is necessary to repeat 10 gr doses of calomel once in 2 hours until 40 or 50 gr have been given and cause them to follow with liquid cath. a [illegible] or jalap or scammony N.B. If there is great difficulty in giving medicine repeatedly, we may give powder of jalap in coffee or fermented liquor or we may give a teaspoonful of the tincture of (not briony root but pure jalap in milk & water which will not be tasted Feeble constitution must have the warm’ bath. # Rx senna zjs man zi senega zii anise seed zis liquorice zfs [illegible] ½ [illegible] This I have held the child with. remember large doses are needed Rx scamm. grs 2 or 3 chalk & diaphoretic antim. this was called Earl of Warwick’s powder & was kept in the shop here. Tart. emet. would be a more certain prop. of art. It produced violent vomiting. Scammony is better united with cal. however. # # Cautiokn about covering the [illegible] with a blanket vide # Cal. was finally substituted for the [diaph.] ant. This Warwick’s powder used to be a shot preparation in this town and parent would send for it. From the uncertainty of the strength of the diaph. ant. however, [dangerous] vomiting sometimes occurred from the use of it 56 effect. In the latter case a second dose may be given two or three hours after adding from an eighth to a quarter of a grain of tartar emetic for a vigorous patient Fifteen or twenty grains of calomel will often empty the stomach and bowels freely & remove all the symptoms. The calomel may however evacuate the bowels but partially & in some instances not at all merely moving the contents of the small intestines into the large ones. In such cases another cathartic is needed for completing the purgative operation If the calomel appears to have no effect, it should be repeated in 5 gr. doses every three or four hours, the patient put immediately into the warm bath & we should commence feeding the child as freely as the stomach will bear with the following R fol. sennae zfs, mannae zi steep in ½ pint of boiling water & if there is a cough, add senedae zii & rad glycyrrizhe zfs. If the stomach will not retain the mixture of senna the powder of jalap or scammony mixed with tea coffee or milk must be substituted, giving 4 or 5 grains in the intervals between the doses of calomel Injections vide p. should be given to assist the operations of the cathartics and repeated every 2 or 3 hours until the bowels have been thoroughly evacuated taking care however not to commence with injection until the cathartics have had time to operate When we have succeeded in procuring stools we shall find them to consist of viscid green mucus mixed with half digested food. Sometimes in the progress of the disease they exhibit the appearance of small pieces of membrane, of There is a membrane [illegible] inflammation of the duodenum similar to that of croup. This indicated by pieces of membrane preceded however by pain in the part obstinate constipation etc. This is a strong indication for calomel which however will not operate as a cathartic until the violence of the disease is broken Warm bath & injections will also be more particularly In some violent cases of the fever where calomel seemed to have no effect. I have known acid as lemon juice advantageously combined with calomel Among the cathartics and laxatives used in the second stage we have the wild liquorice or [illegible] [circa???] which was formerly a popular article and kept in families. It is diaphoretic and laxative and possesses and also deobstruent properties It is said that with this the Indians formerly [died] their porcupine quills # The acids are sometimes used in combination with mercurials I should not use them unless when mercury fails Sometimes it affects the ear & produces suppuration & discharge. It may terminate in effusion into the ventricle of brain. It may terminate by exhaustion Or may terminate in thrush “in which case there is a double translation 1st from the bowels to the head & thence to the mouth oesophagus & bowels 57 & of about the size of petals of peach blossoms, floating in a liquid of the same colour. Such stools as these latter are a sure indication that a farther evacuation from the bowels is needed vide p. 207 They are frequently evacuated by adults in bilious (or common cholic. If such continue it is well to vary the cathartic and give magnesia, or soluble tartar (peerlash & cremer tart.) or phosphate of soda, or any other neutral salt. generally the violence of [illegible] [illegible] & The blue pill may be substituted for the calomel & given three or four times a day, until the stools change their appearance or the mouth is affected, though this rarely happens to children under four years of age. These stools rarely have any smell & as they indicate a want of secretion I the liver & glands of the abdomen, mercurials are peculiarly appropriate. In some states of fever attended with stools of this kind I have known the free use of acids with mercury very useful # After 48 hours the fever generally remits, and sometimes it continues in the form of a remittent for six or eight weeks or more. Very frequently however it changes its seat in the course of 15 or 20 days & terminate in a phlegmous swelling of some of the glands or in phlegmon or is determined to the head & puts on symptoms of hydrocephalus, which are best relieved by blisters behind the ear, a place which is the natural outlet of diseased action in children. They may terminate naturally by a discharge of purulent matter from the cavity of the ear or fatally by effusion into the ventricles of I recollect two cases early in my practice, which continued 6 or 8 months. They were very violently attacked They continued 6 or 8 months coma Hence we should never despair In the latter stages it may be proper to give tonics or those articles which are called tonic very unlike the vegetable tonics however. They produce a [illegible] excitement Giving arsenic is no new practice It is a safe and efficatious remedy, when the dis. continues as a remittent It comes after cal. & tart emet. producing liquid secretions. If long continued it must be followed by bark to restore tone and obviate the debility caused by the arsenic Arsenic can only be called a tonic as it removes disease. It would never be given as a [illegible] is pure debility # # I have used digitalis, in the latter stages to allay irritation # In many cases the fever continues from habit & medicines have little affect. There will be an accession of fever every afternoon. Here give sol arsen 2 drops twice a day which is a full dose for a child ½ years old If this has no effect give it [illegible] times a day” 58 the brain; in two cases I have known them relieved by a thrush. If the disease continue a regular remittent without symptoms of hydrocephalus, it will be proper to give tonics, such Moseley’s tonic solution or if the fever intermits or remits Fowlers solution of arsenic the latter in doses of two or three drops the former from 4 to 20 drops, 3 or 4 times a day. I have known a child 18 months of age cured in this stage of the fever, in the course o f two or three days by taking 2 drops of Fowler’s solution 3 times a day. This article however is liable to produce edema or dropsical effusion & if it does we must substitute the tonic solut. (beginning with about four drops) or some preparation of bark. The dose of the tonic solution will depend upon the irritability of the stomach If irritable from 3 to 6 drops will be as much as can be borne After the inflammatory action has subsided narcotics anodynes are necessary to remove irritation and to procure rest We may use opium, either alone or better combined with ipecac or antimony # Indeed as the skin is usually dry antimony is indicated in almost every stage. The warm bath also is indicated in every stage except in the low typhus state of the fever when it would be too debilitating. Epispastics & irritants are useful in the progress of the disease, to translate action from parts essential to life & in the last stage also perhaps to keep up the action of the system. They may be applied to the abdomen if it is much swollen to the head behind the ears where there is danger of hydrocephalus & Avoid too much heat to prevent tumefaction of the bowels. Terebinthinates a [illegible] oil may be needed proper If pneumonic symptoms blister etc. “If the lungs are much affected, apply a blister to the chest, give expectorants, and pursue the treatment required in pneumonia. Senega & squills are good, but are too stimulating for the earlier stages liquorice anise” By this disease it is sometimes proper to do nothing and omit all medicines in mania etc. In those cases as I have had difficulty to persuade parent to do nothing. I have applied aloetic plasters to the bowels I think they have produced evacuations injections also can sometimes be given Case of a very [illegible] child [furious] parents passed in review before him with roasted apples pears etc. after 26 hours he snatched an apple relapsed in 26 hours they probably had over loaded his stomach however the same management finally succeeded afterwards of the patient recovered. vide p. [20?] The same season I had 3 or 4 more such cases of mania which required to be cured by fasting 59 a large one to the chest if the lungs are affected. “This disease is sometimes followed by thrush when an emetic of ipecac will have a good effect. If the stools are fetid charcoal should be given. If in the latter stages there should be tumefaction and pain in the bowels, the abdomen should be supported by a bandage. In the latter stages also a decoction of the inner bark of the white pine be useful. It possesses some tonic properties” Sometimes in diseases of children the mind is affected, the patient will take neither solids nor liquids & struggle till it is exhausted whenever an attempt is made to administer any thing. If that is the case in this disease we must use the tepid bath & we may a apply for purpose of moving the bowels, a large plaister of aloes and ginger to the abdomen Frequently this derangement & morbid revengeful disposition (according to Dr Rush an affection of the moral faculty is so great that we must wait even for 24 hours or more without administering any thing. It may require great prudence and judgment in such cases, to satisfy the parents. Before leaving the subject I may observe, with respect to the propriety of the course I have directed in the commencement of the disease, that if the cathartic which we administer first produces emesis we may be sure that the alimentary will be operated on, & also that we often require a remedy more powerful than the disease, just as in croup. “As to diet meat must be forbidden but sometimes salt food is craved. The weak chicken broth is good. The dis. is something very rapid & violent Fever as violent as the constitution could bear Collapse from the violence of action Parents considered the patient & dead After the mustard was applied as soon as the skin was reddened a blister was applied, which produced a sore 2 or 3 months in healing “In one hour pat. revived” Nervous system affected Irregular action such as after collapse of cholera Strong clonic spasms once in 15 min. “Pat. kept under a constant [narcosis]” Antispasmodics & tonics finally In two or three weeks [illegible] recovered some strength It was called the child that died & returned to life again The above is account of the disease as it most commonly appears. It is different however in different years sometimes effecting one part of the system sometimes another A practitioner keeps this [illegible] [illegible] 60 Case of a female child 2 yrs of age. The disease ran the most rapid course I ever witnessed. The whole system became affected; the pulse was full & frequent, the skin hot & the tongue furred. In 24 hours the disease came to a crisis and exhausted the excitability of the system; the pulse grew faint, the skin cold and the respiration languid the patient became insensible & was apparently dying sinapisms were applied to the abdomen, ankles & wrists & heated bodies put into the bed, to restore warmth. After the sinapisms had been on an hour and excited some redness, epispastics were applied in their stead. Ammonia & ether were put into the mouth & caustic ammonia was applied to the nostrils to excite Inflammation so as to blister. Ether was also put into the mouth In about two hours the system was resuscitated. Immediately a train of most violent nervous symptoms followed the chill became convulsed almost instantly. After trying antispasmodics in vain the convulsions were checked by laudanum, 6 drops, every two hours. The laudanum lost its effect in two hours & needed to be repeated. The blister on the chest produced a deep ulcer which was difficult to cure Finally tonic solution was administered. The child recovered Child of Mrs “Moulth???] Child of N. Beers’s vide p. 208 diseases and consequently meets with no new disease For they do not make sudden transition as in botany plants he is guided by symptoms & by the operation of remedies Appendix to Mes. fever acute marasmus This disease sometimes appears in an acute form with great irritation Sometimes terminates in hectic Patient will run down very rapidly [illegible] appearances enlargement & [illegible] of mesenteric glands “Called” consumption of the bowels” or Marasmus” Mesenteric fever is thought to terminate in hectic Probably it does especially in scrofulous patient and in those bad cases where the tubercles with a mesentery ulcerate “The pain in the bowels is no usually very severe but of a continued aching kind generally better removed by [camomile] injections than by anodynes” 61 Mesenteric Fever Marasmus tabes [illegible] [illegible] This disease arises from obstructed glands in the mesentery & is accompanied with morbid secretions of the stomach & liver bowels. It is sometimes the consequence of some other fever. It is often connected with scrofula, & it is apt to be attributed to worms. The disease attacks children of from two to ten years of age. Symptoms. The fever is of the intermitting remitting kind, with irregular paroxysms attended with tumefaction of the abdomen, costiveness, indigestion, loss of appetite & very irregular appetite & with paroxysms of pain in the bowels. The patient complains much of its bowels, but the affection seems to be rather distress then sharp pain & is neither constant nor regular. The countenance is very pale except when the cheeks are flushed with fever & the limbs are emaciated This is generally a chronic disease, but sometimes it is acute, & exhibits strong marks of irritation in the system. It may terminate in hectic. Dissections exhibit an enlargement of the mesenteric glands. Causes. It is sometimes as has been said above, the effect of another fever. Among the poor, with whom it is most frequent, it is caused by coarse and unwholesome diet. Children born of scrofulous or gouty parents are more subject to it & hard labor by the mother during the period of gestation may have some influence in predisposing to causing this disease in the child. Patients in this disease are subject to paroxysms of pain 62 The indications are 1st to empty the bowels and to keep up a gentle peristaltic motion in them 2nd to change the secretion of the chylopoeitic viscera. 3d to remove paroxysms of pain 4th to remove the obstruction in the lymphatics. 5th to impose the digestion & to invigorate the system generally 1at To move the bowels and keep up a gentle peristaltic motion mild mercurials as blue pill or calomel & chalk should be given & at the [illegible] time friction as in almost all chronic [illegible] complaint should be employed, upon the abdomen, and persevered in by the attendants. A very good mercurial preparation, will be a pill of four parts gr. blue mass and one 1 or ½ gr of ipecac adding a little opium ½ or 1/8 gr of the bowels are very irritable. If this preparation is not sufficient calomel may be substituted in a dose of 4 to 6 grains. The tincture of rhubarb has in some cases answered well as a laxative & corrector combined with neutral salts and aromatics 2nd For changing the secretions, we must rely upon the articles just mentioned, and also upon those to be mentioned under the 4th head 3d For alleviating sudden paroxysms of pain injections of a gill or a half pint of camomile tea have been found serviceable. If these fail give a camphor injection The pain is relieved by opium plaister There is but a small quantity of iodine and [illegible] effect appears to be produced than shd result from the small quantity of iodine Neutral salts in connexion with tonics have undoubtedly [illegible] deobstruent powers 63 4th For removing obstructions of the mesenteric fluids burnt sponge has been thought very efficacious. I formerly questioned whether it had any superiority over soda. Now it is supposed that all the virtues of the article are owing to the iodine continued in it. It would probably be [illegible] better better to give tincture of iodine in doses of 2 or 3 drops. Still the burnt sponge containing carbon & alkaline matters may have peculiar properties The neutral salts given with tonics have some influence in removing these obstruction It has been proposed to use mercury by injection for this purpose. I know not that it has ever been tried For the indication I have been in the habit of employing the muriate of lime & here given it in connexion with the mercurial pills mentioned under the first head It may be made by adding muriatic acid to chalk or marble & the dose for a child of 3 or 4 years, should be from 5 to 50 drops, given in tea coffee or milk. It is best to begin with a small quantity, say 3 drops & increase by one drop at every dose until the stomach is offended remembering that the stomach bears the article best if much diluted. The muriate of barytes might be used; also the carbonate of barytes is used in dose of but 2 or 3 grains, it being a powerful article. But iodine is probably the best article that we know of Other articles containing iodine, have been used besides burnt sponge, as [fucus] [nodasus] & vesiculosus [reckoned] vide scrofula mur. [illegible] dose 4 or 5 drops in milk & water for a child of 3 or 4 years increasing to 50 even 100 perhaps This [illegible] is not to [illegible] [illegible] it iodine as to be substituted by the latter We are apt to neglect an old remedy as a new one comes on The tepid bath shd not be used when the system is too much debilitated It excites the action of the mucous membrane and of the skin not affecting particularly the blood vessel add a little spirit to make the opium [illegible] if necessary 64 Muriate of lime has the important advantage of exciting the action of the skin which is generally torpid. Hence also the tepid bath has been used with success in this disease The flesh brush too if thoroughly applied several times a day will have a powerful effect. 5. To improve the digestion and invigorate the general system Carbonic acid is a most grateful stimulant to the stomachs of patients in this disease. Hence soda water and other effervescing mixtures, may be recommended spruce bar also & similar articles, if they agree well with the stomach. Aromatics as ginger & spice may often be added to them with advantage Among the tonics which are used to invigorate the system. Iron is very often employed & frequently with good success. The mildest preparations least irritating are the best, such as the tincture of the muriate, the martial flowers & the alkaline solution. Still iron is apt to cause irritation Cold bathing is a good remedy for invigorating the system but if the patient is much debilitated, a cordial should be administered previous to using it When the patient is much debilitated I have found anodyne plaisters upon the abdomen give great relief (where opium did not agree) I have used Noel’s plaister (similar to dyachylon) with soap mix opium zii with zfs of this plaister & spread it sufficiently large to dover the whole abdomen Children are very fond of potatoes but they should not be allowed, unless cooked so as to be dry and [illegible] and then thoroughly mashed Some vegetables as spinach, [illegible] & asparagus may be allowed but only in moderate qualities Preparations of meal of [illegible], especially fried, are bad Rx dough roll it in flour and then cut into thin slips, twist & bake them for [some] hours An excellent preparation for dyspeptic batter than crackers called twisted bread In making broth avoid adding rice, flour, etc. which will make the compound approach the nature of pastry and be more indigestible. Make broths as simple as possible & season with pepper & salt 65 Under this head may be ranked the use of the terebinthinates which have a valuable effect upon the mucous membrane of the alimentary canal The best article is a decoction of white pine bark, which is milder than any preparation of the turpentine of the shops Regimen. Flannel should be constantly worn next the skin to keep up an action in it. The patient should take exercise in the open air whenever the weather is good & damp easterly winds should be carefully voided as they have great influence in all chronic affections particularly glandular of the bowels. Friction & cold bathing have been already mentioned. Diet. This should be carefully attended to Raw fruits, potatoes and other garden vegetables, corned beef & in short all articles which are not of the easiest digestion or which have any tendency to ferment & become acescent in the stomach should be forbidden & caution should be enjoined that the stomach be not distended with liquids, so as to interrupt digestion. The diet should be dry consisting of toasted bread & farinaceous vegetable substance, as arrow root etc. well boiled & seasoned with a little wine & spice. If meat be given it should be broiled & eaten, with condiments. In some cases a piece of lean beef that has been partly broiled & then boiled, makes a broth that is grateful & sits well on the stomach. But if there is much dyspepsia, broth of any kind a not good If this fever terminates in hectic the mineral acid shd be used Undoubtedly however the affection may be produced by excessive purging vide next page low states of fever in adults also for the state of the bowels occurs much oftener than some phys. are aware of “The gases may arise from the ingestion, from a fermentation of the natural secretions, or, as I think from a direct secretion of gas by the intestines. this alone would see to account for the rapidity of its production” sometimes small watery stools 66 Tympanitis In diarrhoea dysentery & constipation with fever & typhus fever after these diseases have passed the first stage, the bowels of children affected with them, are liable to be affected with tympanitis. a troublesome symptom This state of the bowels may occur of itself about the time the febrile action begins to subside, or it may be brought on at an early period by the use of astringents, or by heat produced, either by too many bed clothes or by hot articles applied to the body for the purpose of exciting perspiration it is important to examine daily the state of the abdomen in children affected with bowel complaints, that a tympanitic state may be obviated, as soon as it begins to appear The abdomen is [swollen] and elastic to the touch feeling tense like a drum head under the fingers We can tell as soon as the hand is applied whether the swelling proceeds from inflammation, or from imprisoned air, for in the former case the pressure will cause pain The proximate cause of this state of the bowels I believe always to be a relaxation of the villous coat of the intestines & a deficiency of peristaltic motion in consequence of both which the villous coat falls down & forms a valve which confines the gas, while at the same time there is a morbid secretion of all the chylopoeitic viscera which [illegible] the evolution of the gas In the first stages of tympanitis, the alvine discharge usually cease even if there had been diarrhea & dysentery before & the little patients exhibit signs constant [illegible] not acute pain of great uneasiness from the unusual distention of the “It is thought by some that tympanitis is always occasioned by bad treatment in not giving cathartics enough at the common [illegible] Such persons probably do not examine the abdomen of their patients with sequels of severe bowel complaints. Tympanitis comes on whether cathartics have been used or not and nothing is more likely to bring it on than an excessive of cathartics at the commencement of the disease” The temperature had been raised above it secreting [illegible] & the child might have died “I am very partial to diaphoretic measures in general but must confess it is often abused If carried to excess it rapidly exhausts the patient also if excessive heat as aplied and the pat. does not sweat.” 67 bowels. In the progress of the disease tympanitis the child frequently comatose. The tympany is not always to be regarded as a dangerous symptom it sometimes indicates a favorable crisis, yet if it is accompanied with coma, there is danger that the brain may become seriously affected. If symptoms of congestion in the thorax exist, the disease of the thorax should claim our first attention, and the tympanitic state of the bowels be treated as a [illegible] complaint Treatment. The indications are to evacuate the flatus and excite healthy action of the viscera of the abdomen If the disease has been produced or aggravated by heating applications too many bed clothes or too confined an atmosphere, the heated substances should be removed, the bed clothes thrown off & air admitted freely to the patient. In the summer of 1814 I was called to a child sick with dysentery whose bowels became extremely inflated in consequence of filling with the steam of boiled potatoes in [illegible] the bed in which he lay The child because if much [illegible] & [illegible] was so difficult that it was thought to be dying; but upon removing the potatoes throwing off the bed clothes & opening the doors, the symptoms were at once amended & in the end the disease was completely removed by the use of a little [cajeput] oil in water and laxatives For removing the flatus of the bowels we may use enemata of the decoctions of aromatic plants or suds, such as catnip, camomile; the seed of fennel caraway or masterwort seeds or the essential oil of such suds may I prefer camphor to any other articles 3 or 4 [illegible] IN colicky complaints etc. I have known more benefit [illegible] injections of camphor in milk & water than from any [illegible] articles and that too after the most violent purgatives had vailed. I know of no article which operates so well in relieving irritation of the pelvic viscera [Anodyne] balsam Rx vol. [lin] zi [illegible] camph “Sometimes blister the abdomen” 68 be injected in milk and water. But I think I have experienced the greatest benefit in the case of children from the injection of a teaspoonful 2 or 3 of the tincture of asafoetida in a gill of warm water. It unites more readily with the water of a little milk is added A pipe of ivory or the pipe of a common injecting syringe may be introduced into the rectum as is recommended in hysteria, for the purpose of evacuating the flatus. I have sometimes used an elastic catheter with success The peristaltic motion of the intestines is to be excited and healthy secretions induced For this purpose we are to apply friction with dry flannel to the abdomen and mild cathartics are to be given. The latter may be jalap aloes rhubarb etc. with castor oil to work them off If frictions do not succeed, we may apply volatile liniment camphor, oil of origanum & finally epispastics We may likewise give internally cajeput oil in 3 or 4 in sugar oil of mint, oil of caraway, asafetida zfs to si etc. which is [illegible] to offer [illegible] its stomach & is not offensive to the taste and magnesia with [illegible] & cubebs [illegible] [illegible] or guaiacum Dr Good classifies [worms] according to their locality yet he makes mistakes as to their locality Much has been under the subject, and the remedies are almost innumerable. It is rather difficult to select the most important parts of the subject 69 Worms This subject naturally follows that of bowel complaints From testimony which cannot be invalidated it appears that worms of various sizes and forms have been found in almost every part of the human body. It is only in the alimentary canal however, that they occur with any frequency and give rise to symptoms, from which we are led to infer their presence Those worms which are of anomalous kinds, or are found in anomalous situations (oftenest perhaps in the lungs & frontal sinuses) as they are of rare occurrence & as the indications of their presence were either very obscure or altogether unknown wanting are interesting only as curiosities and will be passed over, without any notice, except an occasional reference to the fact known with regard to them “Worms in the alimentary canal are so common, as to have given rise to a class of diseases called verminous & a class of therapeutic agents called anthelmintics. The kinds of likewise of worms which occur in this part of the body have been thoroughly investigated & we are in possession of a large mass of information upon the subject I shall consider this subject under the following heads 1st The kinds of worms found in the al. canal 2nd their origin & that of worms in general, found in the body 3d the general effect they produce on the system & the general symp 5th the morbid effects produced by each species, with their treatment 4th the general treatment of verminous diseases 70 II. The genera of the common intestinal worms are three; toenia ascaris & tricephalus Of the tania there are two species. Tania solum or cucurbitana & t. lata or vulgaris. Of the ascaris there are also two specis of a. vermicularis & a. lumbricoides. 1st Tania This a long flat worm varying much in breadth and thickness which is formed by a chain of flat articulations, united by a border or edge. The accounts of the length of this worm are almost incredible from thirty to a hundred feet. Taenia solum (called also cucurbitina or gourd seed worm & the armed taenia) is distinguished by having the head forked and surrounded with papillae or long fangs (holders) by which it fastens itself to the mucous membrane. The broken off joints have when discharged the appearance of gourd seeds. hence its name of gourd seed worm. Taenia bata (or vulgaris the unarmed taenia) has an external form like a ribbon joints scarcely perceptible & is white and seen transparent. The head is narrower & smaller & the papillae not elongated 2nd Ascaris vermicularis & a lumbricoides The first, a. vermicularis (thread worm, pin worm & when existing in number called ascarides) is filiform, slender at both ends & from half an inch to an inch in length & of the diameter of a small thread found generally in the rectum & though not confined to that part of the intestines. It feeds on the mucus of the intestines & produce its young in immense quantities. It is found in the stomach & called maw worm 71 Ascaris lumbricoides (or [illegible] long round worm) is perfectly round & from four to ten inches in length bearing a striking resemblance to the common earth worm It is said sometimes to perforate the intestine with its mouth 3 The trichocephalus now called [tric???] is a small capillary worm from an inch to an inch & a half or two inches in length. The body is about half an inch in length & Is terminated a tail which is twice as long & end in a fine hair-like point In addition to these worms have been reckoned two others the vesicularis & the gordius. The former is a small vesicle found in the brain (sometimes in great numbers) & containing many small worms. It is now considered a hydatid & is excluded from the subject of worms & verminous diseases The gordius (horse hair worm) is found in soft stagnant waters from four to six inches long & twisted into various knots & contortions” Good. They are sometimes found in the earth in great numbers they turn black on exposure to the air & resemble horsehair, hence their name of horsehair worm They are very common in our vicinity They are rarely found in the human stomach. I have known them coughed up in abundance from the lungs; when they had probably come from an abscess in the liver. It gives rise to a severe disease among the [lapladens]. Vide Good. The maggots of the common house fly & the’ larvae of many other insects, have occasionally been met with in the alimentary canal of the human body vide Good What were formerly called vesicular worms are now considered as hydatids. [Brera] or worms recommended An attempt has lately been made to revive the doctrine of [equivocan] generation. The learned advocate has attempted to fortify his opinion by the analogy of vegetables. But where the experiment has been made the seeds of the forest trees that come up as [illegible] may be found at the roots of the young trees Hyoscyamus formerly was common here but is not now However when the gourd is broken in the college yard Hyoscyamus springs up. It has also in the soil brought from a cellar in Chapel St. Leeches & a variety of insect are undoubtedly taken in in water etc. In Duncans [illegible] we shall find an account of a number of caterpillars [illegible] by a child produced by eating cabbage leaves I think I have never known an instance of worms in children while nursing 72 II II. The origin of worms in the human body Worms arise from eggs. Some multiply by depositing their eggs to be afterwards fecundated by the male. Others are propagated by copulation between the two sexes While a third kind of the taenia fecundate themselves. I have spent much time in investigating the origin of worms in the human body but must confess that I cannot satisfy myself upon the subject. It has been supposed that worms found in the human body are produced from eggs deposited by flies about the rectum, at the time of going to stool. Were this the fact, they ought to be more abundant in summer than in winter, while the reverse is the fact. I am inclined to think that the rudiments of worms are contained in certain kinds of food as apples pears, cider water & unboiled fruits and vegetables. In infer this from the fact that worms make their appearance, oftenest when such articles have been taken & disappear when they are avoided. If confirmation of this view of their origin we find that children are rarely if ever affected by then when under three months of age & seldom while they are nourished from the breast. For though some have asserted that they have seen worms in the bowels of children within the mouth & even before birth yet the fact is not well ascertained. Breras opinions, also adopted by Good speaking of the fluke worm There is no doubt of the fact of worms within [fetus in uteri] 73 Brera thinks that the minute eggs of worms are absorbed into the circulation He says “when we consider that the eggs of worms are so small that they are not perceptible by the microscope of Hoffman and these eggs themselves are masses of small eggs, nothing is more probable than that the eggs of worms are absorbed by the lymphatic vessels, pass in to the circulation pervade the system with the blood & are deposited in the various parts of the body, where they enlarge and unfold themselves when circumstances favour their development.” If worms are found in the foetus, the fact will favour this idea that the eggs of worms are carried into the circulation. It may be remarked also that the parts of the body which favour the development of their eggs are those abounding with mucous The hypothesis of equivocal generation is neither specious nor probable. It derives no support from analogy aid from reason, nor countenance from fact In its operation it is worse than useless as it tends to obscure truth by substituting conjecture while it disregards with the most vague and licentious imagination the boundaries between the animal and numeral kingdom & ascribes to chemistry what pertains only to animal life When the creator first gave being to the natural world, every part of the vegetable and animal system was brought into existence by an extraordinary exertion of productive power. They were not moulded by the slow operation of time & the cooperation 74 of mechanical and physical forces, but he spake and it was done. But since that first act of creative power, we find are that these creatures are propagated and perfected by processes more gradual successive and [operose], many of which may be traced by human wisdom and admit of being regulated and controlled by human culture & ability Rosenstein says “from the eggs of a fly proceeds a fly, from the egg of a hen a pullet and not a serpent, from the egg of a goose, a goose and not a fish So from one worm is produced a worm and nothing else” II II II. The effects of the presence of worms in the body When the seed of worms are once developed in the human body, the health is more or less affected, and the morbid symptoms which then appear are in proportion to the number of size of the worms the sensibility of the part they occupy and the general morbid diathese which takes place at the time, whether the cause or the effect of the worms Worms in the alimentary canal are less frequently the original cause of diseases than is generally supposed, inasmuch as in many cases of disease where they exist, the disease was merely aggravated & not originated by the worms & all the symptoms of worms from which it is common to infer their presence, may be occasioned by 75 undigestible substances for a diseased state of the bowels Worms are often also found to have existed & that too in great numbers, where the general health has been apparently good. I well recollect the case of a child in North Milford who fell from a height & was taken up in a state of coma from the concussion. A dose of calomel was given him which brought away twenty or thirty large worms. The child had been healthy to all appearance previous to the accident. Some physicians go so far as to say that worms are necessary for the health of vigorous children that they are nature’s scavengers a natural provision to destroy the superabundance of food taken into the stomach. Dr Rush was of this opinion. The opinion supported by Dr [Parr] It is a fact beyond controversy that very healthy children have worms with out manifesting any symptoms of their presence until the supervention of some other disease causes them to make disturbance in the system. It is but seldom that they are the excit. cause of dis. The following are some of the ways in which worms are injurious to the system. They may be injurious from their number obstructing the bowels and consuming too much food. They are particularly hurtful by the irritation which they produce when the irritability of the bowels is excited by fever. They sometimes threaten suffocation by rising in the oesophagus & in one instance a single worm I have known to lie in the fold of a volvulus of the intestines so as completely to obstruct the passage 76 Linneus attributed the dysentery to a worm or insect [illegible] dysenterical [languis] the measles to a similar origin. Various authors the itch, sigler, petechiae lusitanus the syphilis martin the elephantiasis nyander, eruptive & contagious diseases in general lancissi, plague, remitting & intermitting fever considering miasm [it] being a collection of insects # some authors, toothache Dr [Adam] observes cancer itself is nothing more than an animalcule a worm or an insect. It would seem from such speculations, that a great part of the diseases which flesh is [illegible] to result from a superabundance of vitality and that as Good remarks in his [illegible] corruption is no longer the triumph of death over life, but of life in one form over life in another. Such fancies lead into the wildest speculations of equivocal generation & relinquish all principles & all limits in natural history. # Vide N.Y. Rep. about the year 1815 77 Symptoms of worms. Those children are most frequently troubled with worms whose powers of digestion are weak. The symptoms of the presence of worms in the alimentary canal are very equivocal, for they may all proceed from other causes. They are countenance pale or flushed sad and dejected livid around the eyes, eyes sunken eyelids swelled pupils dilated itchings in the nostrils, head ache after taking food, mouth water [illegible] filled with saliva, breath fetid, great thirst, grinding of the teeth in sleep, starting in sleep fainting vertigo, palpitation of the heart, irregular pulse & cold abdomen bowels flatulent costive or loose colic throbbing in the bowels severe from [illegible] the small [intestines & umbilicus] appetite irregular & craving loss of appetite pain in the stomach when empty, which is relieved by food urine increased or diminished turbid and milky, stools irregular, containing much mucus nausea & vomiting Sleepiness particularly after eating, bloated countenance swelled nose & upper lip, paleness of the lips, irritation about the mouth, rubbing the nose, itching at the anus irritation about the neck of the bladder dry & convulsive cough difficult respiration sense of suffocation paroxysms of suffocation body emaciated frequent flushings of fever with irregular pulse convulsions, epilepsy and partial palsy. Of course these are not all present at any one time Chorea catalepsy & epilepsy are produced sometimes, by worms Dry convulsive cough Diff respiration In addition to the other symptoms there may be these of irritation of the lungs producing cough also irritation of the brain [772] It will be impossible to class all the articles inasmuch as we do not certainly know the modus operandi of many articles which yet have sustained their reputation for [illegible] Much stress has been laid upon the operation of cathartics in evacuating the [illegible] which the worms generate by their irritation, just as irritation in the lungs produces [illegible]. But then the [mucus] although it forms [illegible] for them, an effect more than a cause, and the worms will make [mucus] enough for themselves Probably many caths act by their acrimony upon the worms themselves. Others by the violence of their operation dislodges them. “Aloes are beneficial in mild cases as a tonic when there is no excessive irritation. If there is excessive sensibility & irritability they are improper as they irritate the rectum they may be given by injection When there are symptoms of worms though no worms exist aloes are serviceable in the form of elxiir prop.” 77:a. IV. [general treatment] In the treatment of patients afflicted with worms two general objects seem to have been pursued both in popular practice & in that of physicians 1st to destroy & expel the worms themselves & 2d to obviate their effects upon the system & at the same time by the improvement of the general health of the patient, prevent their recurrence and increase This second indication will often coincide with the first, inasmuch as a diseased state of the body is the most favorable for the multiplation of worms Of those remedies which destroy or expel the worms themselves we have three kinds 1st those that expel them by strong cathartic operation 2nd those that act mechanically upon them 3d those that are prisoners to them. 1st Although strong & even violent purges may be used to drive out an accumulation of worms in the bowels yet they should not be often repeated as they would increase the weakness & irritability of the stomach & bowels to such a degree as to favour this increase. In general calomel will be the best cathartic inasmuch as it will tend to promote a flow of healthy bile & to restore healthy secretions. In Europe the gall of animals has been administered. One of the best forms for the administration of cathartics is that of alkoholic tincture, for the sake of the joint effect of the alcohol hence elixir proprietalis in teaspoonful doses & the tinct. “The bark of the button wood taken from the north side of the tree has been recommended. It is a nauseous bitter & a cathartic good” # “It is a question whether cowhage acts mechanically or whether it contains an acrid principle like that which exists in the nettle” # One of the remedies that I have most reliance on for ascaride in tinct [illegible]. Fill a bottle with the young inner bark fill the interstices with [prosp] spirit & give I to zfs night & morning It is an old remedy and better than tinct aloes It is tonic & deobstruent” Some of the acids to be narcotic, are more probably active merely by their pungency, odour etc. 77:b. of hickory bark or buds have been found very serviceable Podophyllum peltatum is much used but is probably not better than other cathartics. The best form would be that of a tincture 2 Mechanical remedies are not now used. Cut hair has been given cowhage though some doubt whether the operation of this is wholly mechanical. I have thought that the root of osmunda given in pieces acted mechanically The filings of tin, formerly were much employed as was also an amalgam of tin & mercury. There is a curious account in one of our journals of a man in Kentucky who took a pound of the amalgam & was unable to expel it from the bowels The mass lodged in a part of the intestines & could be felt externally It was very troublesome to him when riding. Oil has been given with the intent that it should fill the respiratory pores of the tape worms & thereby destroy its life. In Madame Nouffeurs recipe The supper of panada is intended to act mechanically by its bulk. 3d The remedies which destroy the worms seem generally to be narcotics All articles of this class however do not have this effect opium for instance. Particular animals are sensible only to particular narcotics as for instance swine are poisoned by stromonium while sheep eat it with impunity. The most valuable article of this class are the two species of spigelia s. [ma??ndica] & s. anthelmia A strange notion has existed about a little innocent [illegible] was considered as the narcotic agent Similar reasoning has been used with respect to denarcotising the opium Opium denarcotised would be not better than bread Spigelia zii in ¼ pt water to a child may be given in divided doses. It is better to give a cath. e.g. cal. or ruhb Spegelia from zfs to zf for an adult Sometimes but rarely it operates itself as a cathartic Sometimes convulsions are produced Our pink is bad because it is gathered by [illegible] packed in hogsheads & the rotten saved & the rest [illegible] The emigrants from St. [Illegible] brought what they called worm syrup which they said shd be given in the night because it affected the eyes S. [anth.] is [illegible] S. [illegible] about zi if S. anth. “Pink is given more especially for the [round worm] & sometimes for the tape worm” [illegible] [illegible] & [areca] [oleacea] zii to zfs “The French use the syrup of peach flowers & seeds They first give sulph either zi in [illegible] decoction male form & an injection of the same. They probably act by their prussic acid” 77:c. The former is the one commonly used in this country and in England It is called Carolina Pink. This is a most valuable article and is useful not only for its operation upon the worms but for its effects upon the system, in allaying the irritation which they occasion. I have prescribed it for a cough & other symptoms of irritation where I had no reason to suspect the existence of worms Then given for its effect upon the worm from half an ounce to two ounces should be given in decoction in the course of the night, accompanied with rhubarb or some other cathartic to drive the worm off while in a state of intoxication. It may be given in powder in a dose of from 10 to 20 grs The French W. Indies s. anthelmia is used & called wormgrass. It is a stronger article than ours The French use the article in form of a syrup & give a teaspoonful at a dose. Veratrum subadilla & helleborus [fetidis] belong to this class and have been given in doses of 2 to 6 grs for children In Europe the most famous article of this description has been the Felix mas Other articles of this class are camphor, prussic acid & tobacco The bark of the cabbage tree (of which there are two species vide Good) is found highly valuable in this way by the West India physicians Other articles which have been said to be successful in cases of worms owe their success apparently to their acrimony in whole or in part, such as the terebinthinate oils Oil of turpentine is the one commonly Various aromatics have been used, as chenopodium [illegible], rue tansy “The leaves of cedar juniper & [illegible] powdered 20 grs They are acrid stimulating and tonic & may have a mechanical action. It might be used to add to the powdered leaves some aromatic as rue ol. tansy [worm] wood etc.” “Melia [azidurach] bark of root or plant zfi to zi act as emetic cathartic & narcotic. Acts more effectually at the south where the recent article is used” 77:d. employed should be given in large doses, when it will prove cathartic. A concentrated solution of salt has been strongly recommended given by the mouth or by injection Ether is much used by the French & perhaps has an effect upon the worms. Some of the other antispasmodics which have been popular may also have some effect upon them such as asafoetida, petroleum the essential oil of the chenopodium etc. Perhaps arsenic poison intestinal worms I have known it cure. Ammonia may perhaps act on them 2 Of the remedies which are designed to have an effect upon the system. In severe affections from worms our first attention must often be directed toward quieting the excessive irritation of the system, by antispasmodics. Various popular remedies for worms seem to have little other virtue The chenopodium anthelminticus & c. ambrosioides called worm seed & the c. botrys. or [juris] oak ar probably valuable, mainly if not entirely a nervine. They may be given in decoction or the essential oil may be used. The garlics are used in syrup or decoction they are nervine 7 have considerable effect as condiments upon the intestinal canal. The ictodes fetidus is of this class & so are the empyreumatic oils, petroleum given in a dose of 10 to 40 drops barbadoes tar etc. For giving tone to the digestive organs and exciting their sluggish action the tonics the bitters & the aromatics are indicated while mercurial [Artemesia] ][santonica] is no better probably than the other bitter tonics Some confusion results from the appellation worm seed being applied both to this and to [illegible] botrys c. anthel. & “Indeed anything which tends to [procure] healthy secretions of the viscera. Of this kind are the mercurial which produce healthy bile which is especially [illegible] to [illegible]” # “Indian corn or maize has been supposed to favour the generation of worms in the body. The aborigines of this country have been peculiarly subject to them perhaps from this cause” Worms are far less common now as are also colic dysentery et. than formerly when cold water & cider were drunk instead of tea and coffee AT the south likewise the negroes who feed more upon crude and raw articles are more subject [illegible] of the plantations it is a rule to give a decoction of melia to the black children once in 3 months # Though you can cure worms generally by calomel yet sometimes they will resist all treatment Eupatrium perfoliatum is used for worms Flowers of [zinc] are antispasmodic so also sulph zinc Dr Rush thought well of [sugar] especially when given in the morning Petroleum seems to be a valuable article a substitute for turpentine It may be supposed dangerous, but I have used it for many years without inconvenience I began with small quantities from fear of danger, but now I give 10 30 or 60 grs It very often to produce no violent effects. Yet we must not conclude hence that it is useless. Asafoetidae for instance produces nothing but a little [illegible] in healthy persons 77:e. preparations & other deobstruents will be valuable adjuvants. The metallic tonics as the preparations of iron & of zinc, the mineral acids, myrrh, bark, the various bitters & the astringents have been found useful I have used alum whey with advantage. Among us the geraniums & all the indigenous aromatics & bitters have been given in popular practice. Alcohol from its stimulating effect upon the digestive organs will be a useful vehicle, for the exhibition of medicines. Condiments used freely with the food, will answer to the same indication The diet of patient troubled with worms should be dry & stimulating, rather than liquid & cold raw fruit, acids cold water & all indigestible articles should be avoided & in extreme cases I would advise that neither food nor drink be taken but which has not been subjected to heat. I have apparently cured patients by this means. “[illegible] toasted bread [illegible] [illegible] vegetable [illegible] though they occasion [illegible] dyspepsia” A multitude of heterogeneous articles have been used as anthelmentics, besides those already mentioned; some of them are sugar; worm-wood; rue; peach flowers; bark’ of prunus virg; valeriana selequa used by the French; muriate of barytes; injections of mur. of tin (Alibert); oxide of tin grs iii with etr. of juniper (Alibert) mur. of amm. of linseed; mur. of amm. [illegible]I with jal. or rhub 10 gr.; all the forms of ammonia; crude mercury; merc. boiled in water; aethiops mineral; artemisia [illegible] [illegible] ([illegible] [illegible]) & a. [illegible] [illegible] [s?tonica] worm seed bitter & of some value; melia azedarach much used at the south; butternut bark intensely bitter dose a tablesp. full of decoct cathartic & said to be narcotic; allows asclepiadis I think I have seen the a. [illegible] then beneficial; etc. etc. Garlics seem to do well how it is difficult to say perhaps operate upon the worms. Garlic also will relieve the eruptions of worms. It is though also that garlic prevents worms I have a very good opinion of sulph ether introduced into the rectum used by the Germans, Italians nervine & antirritant. It is valuable both in cases for worms & in those of irritation & affections of liver severe pain in bowels etc.” ½ oz or 1 oz. iron filings taste by [illegible] remedy worse than disease Wherever leaves of [illegible] are recommended you may give our common juniper For the imported [illegible] loses its strength by keeping & drying Rosenstein recommends cold water during the operation of a cathartic He recommends effervescing mixtures to destroy the worms by carb. acid An old remedy of the tonic kind is alum whey Rx milk & water equal quantities & put in [illegible] [alum] to [illegible] give the whey [illegible] children takes it pretty freely; It is a given in cases of relaxation of bowels and for ascarides & round worm It is of consequence often to have a remedy [illegible] and not require to be forced down 77:f. Various external applications have been prescribed Oxgall & venice soap aa zi made into a liniment with oil of tansy or wormwood; Aloetic plaisters; ether oz vi, bruised garlic zi, camphor zi (used by the German Brera) for a liniment; petroleum mixed with gall; Most of the patent medicines for worms [illegible] or both contain calomel, Storr’s lozenges are calomel with sugar & gum. These are his white lozenges. His brown are resin of jalap, gum tragacanth & calomel. Good on the authority of the Germans recommends [illegible] milk Electricity A popular article (cath.?) is decoction of [plantanus] occidentalis strong bitter For ascarides I rely as much as any thing upon a saturated tincture of the juglans [illegible] & [illegible] All the indigenous bitters as cherry bark [illegible] melia [azedarach] zii of recent root is divided doses ½ pt water. When dried & long kept it is apt to disappoint here. It is acrid [as the] narcotic & cathartic a powerful article The berries are also narcotic causing lard to fall down not from [choking] as has been thought The [planters] think it too powerful for [white] children! Tape worms frequently produce headache [illegible] about the umbilicus yet generally produce a sense of weight. Yet I have known persons evacuate them when they had not been suspected Case of a man who had kept taking remedies for a catarrh Finally a medicine ? brought away to his own surprise and that of his physician a tapeworm Perhaps vomiting occurs oftener from tape worm than from any other species # “When the worms are very numerous, there is a sensation of something falling from side to side on a change of posture” 78 V. Symptoms of each of the kinds of worms with the treatment. 1st taenia solum. This worm generally inhabits the upper part of the intestines & adheres so firmly as to be removed with difficulty It is sometimes solitary but commonly in considerable numbers. When brought away from the bowels many of the joints are separate & have the appearance of gourd seeds hence the name. 2 T. lata or vulgaris This likewise inhabits the upper part of the intestines and is usually in families of three or four Both are called by the common name of tapeworm They may exist without any apparent symptoms of worms or they may give rise to the severest affections In general they are attended by severer pain in the bowels & more violent symptoms in general than the other worms. The diagnostic marks of their presence in great quantities, are sense of weight in the abdomen, # irritation of the stomach nausea & vomiting loss of appetite, irregular appetite weakness of the chylopoietic viscera, bloated countenance emaciation of the body etc. All these symptoms however may arise from mere irritation of the stomach of a child Adults are more generally affected with tape worms but children sometimes have them. For the taeina solum t. lata or vulgaris or cucurbitina the gourd seed worm the spirits of turpentine has been very successful. Though not prescribed by the physicians it has been used as a popular remedy here for more than T. lata fifty years. I have known a man of intemperate habits No cautions are given about the use of the article (so far as I know) But if it does not act as a cathartic immediately, it will produce great irritation especially of the urinary organs I recollect the case of a lady who had been treated with aph turp. in N.Y. taking 2 or 3 ounces Violent vomiting & catharsis had been produced and the tone of the stomach and bowels seemed to have been permanently destroyed Worry had indeed been brough away, but then they would come away themselves & the relieve was fallacious In delicate cases it had better be combined with castor or sweet oil In the case of the lady cath seemed to do no good, they would indeed bring away large quantities but they would return in a few days. I put her upon arsenic but she left town and I have not heard from her It is difficult to tell how arsenic operates whether upon the worms or producing healthy bile For the t. lata the spts turp. seems to do better 79 take a wine glass full of spirits of turpentine to expell a tape worm Though an habitual inebriate, he said he never had been so drunk in his life & large tape worm of this kind? came away # It is said sometimes to intoxicate & sometimes to produce irritation T. solum 2d The t. lata is the most difficult of all worms to manage. Spts of turpentine do no good at least in those cases in which I have tried the article In T. solum one case I gave zfs. In another I gave it in teaspoonful doses. In the latter it operates freely as a cathartic a single teaspoonful procuring as many as ten stools Worms were evacuated but they would make their appearance again in as large quantities as before. Indeed any medicine may bring them away for the bowels are sometimes so filled with them that they come away T. solum when the patient is walking, or is asleep. I have known two quarts to be brought away in a day, & then a fresh supply in a few days after! T. solum # Arsenic has succeeded better for this kind? with me than any other remedy, which I have used. In the case of a child 5 or 6 years of age who had both the round & the gourd seed worm the common cathartics were given with some advantage, as some worms were brought away; but the symptoms still continued and the worms passed occasionally with the stools. Fowler’s solution of arsenic was administered in doses of four drops three times a day. In a few days worms ceased to be evacuated the symptoms disappeared & the child has once had no recurrence of the worms [Osmunda] cinnamonea is bitter, subastringent and perhaps deobstruent. So is polypodium vulgare and perhaps more decidedly so The polypodium vulgare & felix mas They are used in chronic affections of the stomach & bowels & thought they have not obtained much reputation for worry in this country yet they have sustained their reputation for 2000 years. It was used by Galen “The [form] is tonic” 80 I recollect case of one patient, a woman, who kept passing tapeworms, in great quantities, for months. After failing with medicines I threw them all aside & tried diet All the food taken was roasted or boiled even the water used for drink was boiled. She was cured. It must be remembered the healthy bile & gastric fluid will destroy those worms & from this fact results an important indication, which I shall presently dwell upon. Felix mas the male form has been considered in Europe, as a specific for this worm. With us the osmunda cinnamonea [illegible] ([hog brake]) has been used as a substitute for it. It is bitter, astringent & sweet. The polypodium vulgare, which is tonic & deobstruent, & other forms may probably be used also The famous fern remedy bought by the king of France of Madame [Nouffleur] is as follows. Take a super of the following panada Rx water lbi [illegible] fresh butter z 2 or 3 bread cut into small pieces zii add salt zi & boil thoroughly. If the patient is costive give an injection of water lb is in the evening olive oil zii salt gr. s. The next morning eight or nine hours after the supper the specific is to be given viz. Felix mas ziii in powder, mixed with 4 to 6 z of the distilled water of the fern or the flowers of the linden tree the whole to be swallowed at a dose. In children the dose is reduced to zi of the fern Two hours after the fern is taken the patient is to swallow the following bolus R. cal. & scamm. aa grs xii Gamboge grs V powdered fine & made into a bolus to be given at one dose to a person of vigorous constitutiokn Ether acts especially upon the nervous system on which account it has been used as an anthelmintic Alibert for taenia gives about zi in a glass of the decoction of the male form in the [illegible] an hour after his doze zi of the ol. ricini are to be given in syrup or in composition the dose to be repeated twice & sometime three times a day The worm is usually evacuated after the first doses Mr [Bonadier] directs an injection of the decoction of the male form to which zii of ether are to be added Mat. Med. art. ether 81 Mathieu adds to Mad. Nouffleur’s remedy the filings of tine & the sulphate of potash The French & German add ether to the same remedy Rothier’s method is Rx powdered savin grs xx seeds of rue 15 cab. grs x oil of tansy gtts xii syrup of peach gr. s. make a bolus Take half in the morning & half after dinner, drinking with each dose a glass of vin. tincture of peach kernels Dr Baurdier gives the following Rx sulph. ether zi decoct felix mas 1 gill taken fasting 4 or 5 an injection of the same decoction with zfs of ether an hour after zii ol ricini or zi of the syrup of peach blossom the worm is discharged half organiz Oil is used in order to kill the tape worms by filling their respiratory foramina. Ol ricini has been given for taenia & other worms in doses of 3 or 4 z Liquid carb. amm. might be given for taenia The German physicians are fond of giving 3 or 4 ounces of castor oil They are fond likewise of peach flowers Within 5 or 6 years the bark of pomegranate has been recommended. Paris says bark of the root [illegible] probable however the office preparation is meant viz rind of the fruit which is the most astringent substance to the [illegible] which we have [illegible] also cathartic! I have not [illegible] N.B. The male form is astringent, and is given to enable the bowels by the tone it gives, to bear the [strong] cathartic afterwards. Hence the union of these give in [illegible] [illegible] may be useful I have seen the worm occasionally in rain water I recollection one man of 60 who informed me he had been troubled with then nearly all his life until he removed his [illegible] Change of place may effect a cure by change of water Probably [illegible] of our cholera are troubled with this worm delicate children only suffering much children troubled with them will be faint, have turns of colic etc. you will be called [illegible] Give an injection, and no worms will come [illegible] yet give afterwards a strong cath. & or repeat the injection and worms will come away proof that they were not in the rectum They probably breed in the duodenum I have known but one case in which they were vomited up. The subsequent cath. will bring away smaller worms More is done by diet int his worm than by any thing else Alcohol in this morning especially its bitter tinctures. Condiments are useful. Worms are less common now because condiments are more used. It is said that the aborigines when they cannot get salt used potash ashes by a condiment The aborigines are said to be very subject to worms # Ascarides sometimes produce severe pain at the umbilicus and colic # “Ascarides though often found in the rectum are generated in the stomach & small intestines. Hence they are sometimes no discharged till the second or third operation Hence they are sometimes thrown up by vomiting. I have examined this point carefully 82 3d Ascaris vermicularis. This worm is always troublesome when it exists in considerable numbers though it is but seldom that they exist in healthy persons in such numbers as to give rise to morbid symptoms. They are very common in children, and not rare in adults & are called by the generic name ascarides These worms are commonly found in the rectum & hence are often said to inhabit that part This is a mistake they multiply abundantly & lodge in the rectum as they daily pass void by sphincter. Sometimes they exist in the stomach in vast numbers (hence called maw worms) so as ever to threaten suffocation by rising in a ball into the esophagus & sometimes they cause severe griping pains by their presence in the small intestines # They pass in the stools & sometimes come away spontaneously at night, they are said even to make their way to the vagina & urethra of females producing troublesome symptoms X Ascarides are most troublesome in the latter part of the day & the first of the night, when they excite an intolerable itching at night [illegible] probably than feeding They give rise to symptoms of general irritation & sometimes to a cough # Ascarides are particularly injurious to dyspeptic patients & they themselves may give rise to the symptoms of severe dyspepsia such as craving appetite, indigestion, faintings. Flatulence, cold extremities pale & sallow countenance, cough etc. The irri “They are attended with violent itching about the rectum general irritation convulsions irregular appetite pale urine flatulence want of vigorous action of chylopoietic viscera increase of mucous secretion darting pains in the abdomen stomach & chest faintness cold extremities the symptoms of dyspepsia sporadic cough” Tobacco injections & tobacco smoke injected are very useful and will often cure. It is not safe for children I have seen great prostration produced in children & I have known an adult killed by a tobacco injection # A physician who had been much troubled with ascarides told me he had tried merc. oint. externally with advantage. “I have used it but was rather disappointed # When the ascarides are in the small intestines, tobacco smoke will do not good & by its debilitating effect will favour their existence “Injections of camphor and milk have done more to remove ascarides than all other remedies I have used. The injection immediately removes the irritation produced by the ascarides & the ascarides themselves. It may be made of milk ziv to spts camph. zi This is the form in which I have used it, probably an emulsion is as good, perhaps a better form” M. M. 83 which they cause sometimes, in children brings on convulsions Whenever, finally, they exist, in the alimentary canal they are accompanied with great quantities of mucus in this part. They feed on the mucus of the intestines, the flow of which they excite by punctuating the mucus membrane Treatment It is very difficult to cure a patient troubled with ascarides. The most immediate relief is given by injection. If the worms are in great quantities & too much “Tobacco smoke is one of the most powerful means we possess for the involved in mucus, they may be completely removed by cure of these troublesome worms” injecting tobacco smoke. Injections of warm water or milk & water will relieve for the time being by washing out the rectum & if a quantity of aloes zis to ½ pt is added a still better effect may be expected though camphor being a nervine & a poison to the worms would be a still better addition. Injections of milk and water, with camphor zii tinct camph to ½ pint, will if preserved [illegible] destroy them 15 grs of [illegible] [saladilla] have been injected. Still the frequent injection, required in bad cases may debilitate the bowels & consequently invite the return of the worms. For internal administration. I have found a tincture of the buds or bark of the hickory given in doses from a tea to a tablespoonful one of the best articles both for removing the worms & for preventing their return Drastic cathartics should not be depended upon for they weaken the bowels & increase their irritability & hence favour the production of the worms. On the contrary calomel & tonics should be given to restore healthy secretion Aloes if given should not be in large doses, for that will irritate the rectum still further, but in smaller ones as a tonic Oily articles shd be avoided as butter, because they relax the [illegible] of the intestines Potatoes, vegetables All kinds of pastry avoided All the metallic tonics are useful as tonics They are thought also to be unfriendly to the worms It is said that forth ascarides a pint or a quart of sea water has been drunk with advantage, producing vomiting & purging. Salt is a good remedy. Dr Rush proscribed a teaspoonful of salt in the morning to a gentler one much troubled with ascarides. He told him after trial than the remedy would not do. Dr Rush gave him, then, for worm powders # For the worm the [illegible] the pink shd be the remedy vide [illegible] “Rhub & cal. are the best cath. but all are useful For children Rx tinct. [illegible] Fowlers solut. cold water” “Common salt ground up with cochineal to colour & disguise the article. The gentleman reported that the last prescription had answered well. Dr Rush also believed in sugar. This more doubtful The asclepiasis have been much used especially for this worm especially A. incarnata called wild hemp It is dried pounded to a fine powder mixed with molasses & given in doses of a teaspoonful Or [illegible] down and make a strong decoction [illegible] the [illegible] with it molasses and give freely until it moves the bowels This much used by the practitioners of the state more than any other article after calomel. it is an article which may always be obtained growing in clayey situation and is safe The other asclepians are similar & may be used S syriaca is the most laxative 84 To prevent the return of ascarides, condiments should be freely used such as pepper, ginger etc. in short all warming and bitter things In extreme cases let the diet be so regulated that nothing shall be received into the stomach which as not been subjected to heat. Mercurial ointment has fasted in my hands. 4. Ascaris lumbricoides the long round worm is perhaps more commonly found in the alimentary canal than any other This worm more than any other is found to have existed in the stomach or intestines while the general health has been good is the presence of worms not suspected. Strong purges may be used to remove them & alcoholic tonic tinctures given to prevent their increasing. For this latter object the carbonic acid has been recommended in the London Med. & Phys. Journ. & in confirmation of the idea I have used soda water with advantage Melia azedorach or pride of India a decoction of the bark is much depended on at the south for their young negroes who are much subject to worms. It loses much of its virtue when dried. The spigelia is also sued but of this I shall speak under the head of general treatment. I recollect with an aff. of the liver wh often vomited up dark [gravous] blood, which had evidently been long in collecting. Finally he was said to have thrown at a snake. Many eyewitness testified to the snake & to its eyes & teeth. I saw it. It was a very large round worm of the kind To be distinguished only by the violence of the symptoms. The same itching at the arms will exist as of the ascarides, but non violent etc. “Treatment similar to that for ascarides. It is more common than is generally supposed. Many of disease & death by irritation from an unknown cause, are probably owing to this worm. In examination the contents of the bowels should be placed upon linen cloth and then this worm can be seen.” For the gordius Linnaeus recommended the angelica Archangelica (not our viz the [atropur????]) 85 5. The tricocephalus is but seldom met with The irritation produced it may be so great as even to bring on delirium & will be manifested by screaming throwing of the hands & [fat] etc. I have found this worm in a fold of the volvulus of the intestines vide Volvulus. I should try narcotics for this worm, but cannot speak from my own experience. I should recommend also an injection of a table spoonful of ether in a gill of water or mucilage. Ether given in this way will undoubtedly pass the valves of the intestines in a state of vapour Vesicular worms, according to the old division of verminous diseases, are met with commonly in the brains of adults & are attended with the symptoms of vertigo, convulsions apoplexy & hydrocephalus. Cases of worms & of colic are much less frequent with us than formerly; owing to the change in our mode o f living. They are said to be very common among the aborigines of this country One volvulus may be received within another a second, a third and fourth time & [illegible]. The whole may then become inflamed, the vessels may run from one to another, and the whole become one complete mass of organised matter or sometimes [illegible] “It may occur in any part of the intestines except the rectum though the colon is often received into the rectum” The symptoms of the two kinds [illegible] [illegible] owing to the different susceptibility of these two portions of the al. canal, and the diff. ages of the subjects of each Nor located in books vide Ed. med. & surg. J where the best account of it is given. Good merely mentions it as an accident that is found sometimes to have occurred in ileac passion “Predisposing of exciting causes” The cavity of the natural stricture may not be large than a goose quill, & such children will be very liable to an occurrence of volvulus This is not a primary disease. It occurs more in some families of [illegible] fibre & [illegible] phlegmatic temperament It may occur from debility of constitutional or that of the bowels [illegible] by bowel complaints etc. Local violence One instance, in here the child was apparently thrown into it by being carried over the shoulders 86 Volvulus or Introsusception This is a disease with which I was at first very much perplexed especially as I derived little satisfaction from the books Volvulus or introsusception is the reception of one portion of intestine within another. It doubtless exists often in a slight degree, when there is a strong action of the bowels & are inverted peristaltic motion & the bowels disengage themselves. Sometimes there is a double involution, or one involution within another. In some cases likewise the cavity of that portion of the intestine is entirely obliterated by the tumefaction of the coats. I have always found in post mortem examinations, that the upper portion of intestine was received into the lower & not vice versa the involution having been caused apparently by inverted peristaltic action This affection of the intestines occurs oftenest in children though adults are liable to it. It would seem also that some families of a leucophlegmatic temperament & delicate constitution are particularly liable. It may be caused by a natural stricture of a portion of the intestinal tube when it will be incurable It may arise from extreme irritability; local violence & injury may occasion it, & the irritation of worms may bring it on. Drastic cathartics may bring on volvulus & hence should be cautiously avoided where there is a liability to it. Bowel complaints, as colic, cholera, dysentery etc. sometimes terminate in one or more volvuli of the small intestines. The disease is more frequent in the summer, when debility is greater & bowel complaints prevail “Symptoms incessant irritation one or two copious evacuations but usually these have ceased entirely before the physician arrives constant efforts to vomit, resembling hicup constant efforts to pass stools & nothing passes but mucus streaked with blood Generally mistaken for hydrocephalus In bowels complaint of delicate children look out for volvulus It is much more common in some seasons than in others. About 10 years ago they were quite common. I had many letters from our students, who met with the disease & disagreed with the phys & gained [reputation]. They frequently sent me such accounts. Sometimes there will be a partial involution of the large intestines [illegible] to relaxation of inner membrane what descends like a funnel & may be felt by the finger # In the large intestines there is not very much irritation than is torpor of al. can. not much vomiting except upon the administration. There is no purging You may sometimes determine that of the large intestine by heaving the peristaltic action discard & stop at the [illegible] This is most common in adults. The symptoms are more mile # It occurs in females who have had long continued effetion of uterus, occurring in females about cessation of [catamen] and from long continued bowel complaints. The [inner] membrane will descend like a funnel An injection will perhaps 87 Symptoms These will be different according as the affection is of the small or of the large intestines 1st Where the small intestines have one or more volvuli the symptoms [illegible] vomiting or Symptoms like those of violent injury to abdomen vide case 1st 6.89 a constant endeavour to vomit as often as once in ten or fifteen minutes the matter thrown up being a greenish fluid or simply mucus. In severe cases the vomiting is attended with a discharge from the rectum at the same time. The stools are fecal at first & copious but afterward they are small in quantity & consist principally of white mucus streaked with blood the blood not being diffused throughout the mucus as “no fecal smell generally” in dysentery, but in streaks or specks. These symptoms are attended by others which indicate great inquietude or irritation such as throwing the h ands & feet, rolling the head paleness of coutenance This set of symptoms resemble those of hydrocephalus & hence volvulus is often mistaken for this disease. The pulse is small and frequent “[illegible] usually occurs in 24 or 36 hours” 2 A volvulus of the colon or rectum is not usually attended with much vomiting unless this is excited by cathartics. It is attended with the ordinary symptom of constipation. There is no evacuation from the bowels unless at times a little blood and mucus. If the passage be not completely closed, an enema thrown-up will remain & not come away if completely closed. it either cannot be thrown up or it returns immediately. Blood often follows the introduction of the pipe. Indeed the inflamed part is often so low as to be reached by the pipe & admit of being felt by the finger. come away immediately. [Schyl?la] of feces may come away And large quantities of mucus may come away sometimes ½ a pint. This is not apt to be fatal. Treat by a strong inject prescribe for the [illegible] with conium [illegible] etc. mechanical means The more cath. you give the more the unsolution is increased therefore give more Give mucilaginous injection, in involution of the small intestines, sufficient to fill the intestines. If it is said that the injection will not pass the valves. I answer that whether by sympathy or in whatever manner, I am satisfied of its utility # Give [illegible] enough to allay irritation I have treated # patients for 8 or 10 days without evacuation & cured them Not long since I had a case in what I suppose there was such a volvulus, for the attendants could not make the child receive injection. “thought the bowels were swelled” The child was suffered to get 8 or 10 days without evacuation & eventually died of another disease with which this was connected # In the incipient stages, filling the intestines with warm water [illegible] recovered. I was led to it from its [illegible] strang. hernia I am satisfied it acts well as a local nervine etc. I would recommend the injection of ether in cold water table sp. to a gill warm wat. will make it fly off. The inject of it is practised by the French & Germans. Other antispas. might be [injec??] is asaf. petroleum etc. 88 We may often hear a rumbling noise proceed as far as the stricture & then stop. Treatment The indications of cure are principally, to relieve the excessive irritation both constitutional & local & to attempt the restoration of the involved intestine chiefly by mechanical means When the small intestines are affected we must give opium and aromatics & depend mainly upon these as internal remedies, until the intestine restores itself. As an adjuvant the warm-bath will be valuable & fomentations or irritants, as mustard & horse radish leaves may be applied to the abdomen. Soothing injections also may be copiously given. The quantity of opium which will be safe at a dose may vary from half a drop to 30 None but the mildest cathartics are safe, as blue pill and aromatic tincture of rhubarb I have succeeded in giving only a decoction of senna & the blue pill [Savage] When volvulus is in the large intestines all our remedies must be given by injection. The warm bath etc. may be used & we may also attempt the restoration mechanically, by means of copious injection repeatedly given & thrown up with force Two cases are related of young men cured by inserting into the rectum & keeping these for a considerable time as spermacete candle with a quantity of opium at its extremity. The first case which I had I treated for constipation with repeated cathartics, which are thrown up etc. The attendants complained that they could not give the injections when I ordered I was ignorant of this case Tried warm bath & every remedy for colic constipation etc. Upon examination at first the colon was apparently wasting at the sigmoid flexure where there was a large tumour which we thought to be a malformation It proved to be a repeated & insolution of the intestines Inflammation had taken place & the whole was adherent, some [illegible] Afterwards I was called too late, to a similar case which upon an examination showed circular appearance Afterwards called in consultation to a child said to have hydrocephalus all the children of which family had died in a strange way. I pronounced the disease not hydroc. but some could not say what was the matter. No treatment was serviceable. Examin showed volv. of small intest. Symptom is above. vide p. 204 The children of the family were subject to diarrhoea & were leucophlegmatic. I afterwards [illegible] the family and was very cautious about cath. giving nothing stronger than blue pill or tinct. rhub. The family raised 5 or 6 children afterwards Case of a student [unaccountable] Dr Munson & Dr Smith at a loss. [Cath.] retained & yet not thrown off by vomiting Sitting by him I observed a rumbling noise Which he said upon my enquiry, he felt & which stopped. I felt the stricture. Spermacite candle, sharpened, opium at [end]. kept up about a [illegible] [renewed] afterwards injection passed up Case of a gentleman on the wharf similar cured 89 Cases. A man over whom a cart had passed without leaving any external injury, died with all the symptoms of volvulus of the small intestines. On dissection the duodenum was found cut entirely in two. One remarkable physiological fact occurred in this case; a cathartic was given by the mouth & produced a regular evacuation from the anus, although the intestine was completely severed. An interesting case occurred to me in which the worm ascaris tricocephalus was found to be the cause The worm lay in this fold of the intestine. Grace Linsey, a delict schoolgirl on was taken with slight in disposition for 3 or 4 days the rejected her food by vomiting then came on constipation with vomiting attended with great restlessness & throwing off the bed clothes, cold extremities, low & small pulse the tongue not much furred, little or no thirst, no tumefaction of the abdomen no determination to the head. She was visited on Tuesday and died on Saturday. A blue pill was given & followed by 15 or 20 grs. of calomel in divided doses No effect was produced though they were not rejected. Opium and stimulant were tried but were not retained. There is no pain but faintness & an uneasiness about the alvine & urinary passages. Both copious and small injection pass up well but produce no evacuation. On Wednesday injections produce stools which are clay coloured. Black vomit came on two days before death. P.m ex. liver very pale little bile in the gall bladder no marks of inflammation cavity containing the intestines very dry as in cholera. Two volvuli were found one in the ileum which was disengaged with difficulty, & one in the jejunum In other cases with similar symptoms I have had supposed there was volv. caused by worms, but have had no opportunity to examine Vide p. 204 [illegible] Lindsay’s case continued. After the examination we accidentally observed some of these worms minute & coiled up among the mucus on the cloths. The worms seem more calculated to irritate the bowel than any other “If it could have been known that the worm was there, perhaps tobacco should aught have succeeded # It is called leg ache in slight affections alluded to by DR Rush Affects the legs, calves of the legs [illegible] continues extends up to the [illegible] coats” It is a disease manageable in its commencement Being a severe disease it calls for decisive remedies The indications are to allay pain equalize excitement & promote peristaltic action by opium by diaphoretics by cath. Cal. in full doses some would call 5 grs a full dose some 10 But if 5 gr. should be given every hour it would amount to a full dose. You may give 10 gr. 2 or 3 times repeated. AT the same time apply warm bath & fomentations not regarding your giving cath. Put drafts at the feet. Follow the cal. with senna, salts etc. But do not be too anxious about the calomel’s operating immediately It is better that it shd lie sometimes in [illegible] vessels With the cal give opium also guiacum & guaicum with dovers powder the latter to act on the skin and the whole to produce a decided [nerve] action affect on the al. can. and on the whole system 89:a. Nervous Rheumatism Infantile neuralgia This is a disease which has never to my knowledge been described in the books, though it may have existed unnoticed I first met with it some years ago, but it is [not] some years since I have seen of a case. It may occur again It occurs in the winter and spring mouths & occurs after exposure to cold especially after the feet have been in snow water. Children are the only persons that I have known attacked # This disease is in its symptoms allied to neuralgia acuta. The affection leg ache is probably allied The attack is sudden after exposure to cold with excruciating pain in the inferior extremities sometimes rigidity of the whole muscular system more or less disorder of the digestive passages (apparently the muscular coat of the intestines is affected) abdomen frequently tense and full stomach sometimes irritable. If the disease advances there is nausea, vomiting, tumefaction of abdomen (appearance of tetanus?_ (coma?) etc. and the patient dies in 4 or 5 days The indications of treatment are to equalize excitement by acting upon the whole surface of the alimentary canal and skin at the same time introduce new action in the system commence with a full dose of calomel 5 to 10 grs or 20 & follow it by senna and manna, or castor oil and enemata “I do not expect that cal. [illegible] I as above will operate at 8 years therefore follow it. Immediately after administering the calomel I put the patient into the warm bath or the feet in to the tepid bath, wrapping them afterwards in flannel or boil cedar boughs in water, roll them in cloths and apply them to the body & feet. Irritants also may be applied to the extremities and to the abdomen Sometimes it will be best to repeat the cal in the course of 2 hours. The stools will be fetid and dark but this must not be considered as an indication for further evacuations as the appearance may be caused by the calomel, and is a sign that secretion is beginning to take place. After producing free evacuations by your cathartic you must keep up a regular course of exciting the secretion by cal. & guaicum with Dover’s powders, especially if pain continues & keep up a diaphoretic action by Dover’s powders calomel and camphor alternately increasing doses if necessary. Calomel and gum arabic, as an emulcent, & calomel and decoction of cedar twigs, as a diaphoretic may be given Give the calomel first in divided doses If cold applications are made to the extremities, to discuss the inflammation the disease is translated to the stomach and death is the consequence I called in the first stages, & am always successful in effecting a speedy cure The irritation of the system is so great that secretion is prevented hence the production of secretion I have been called to patients with [illegible] where little had been done the abdomen was swollen the patient went into a comatose state & died and that too where the disease was not of the most violent form After the bowels are thoroughly evacuated depend upon diaphoretics camphor guaiacum and [illegible] etc. giving so as not to offend the stomach and beginning gradually It is a violent and excessively painful disease and it is a great satisfaction to the phys. to cure it Dark stools [illegible], satisfied “The pain usually begins in the calf of the leg and extends to the contiguous parts. Sometimes it is attended with tetanic spasms & a constant rigidity of the abdominal muscles. The stomach becomes in these cases irritable, and nausea & vomiting prevail. In the progress of the disease the abdomen becomes full and tense, with constipation.” “It should be our leading object to make the muc. men. of al. can. & the cutaneous system active [concert] After the operation of cathartics, if the pain is severe give diaphoretics with opium, as Dover’s powders. Camphor & cal. in small doses as an alterative. If the stools are watery & fetid give opium ¼ gr. guaiacum 1 or 2 grs. camph. 1 gr. Ipecac ½ gr. with cal. repeated till some effect is produced not to salivate, but to this children are not so liable as adults” Young physicians are often called in a case of convulsions as their first case The neighbors & friends (women) have assembled in great numbers and their sympathies are excited. Hence an impression is made with respect to a young physician’s talents which will be of great service or detriment Morbid condition to brain so that ordinary stimuli produce convulsive action Convulsion fits may continue 5 m or from 1 to 2 hrs 90 Convulsions vide costiveness 12:a This is a very common disease of infants. The mortality from it is truly appalling nearly one seventh part of the whole number or deaths of patients under the age of puberty by the bills of mort. in Phil in 20 years Medical writers commonly make two kinds of convulsions idiopathic and symptomatic, the former arising from some morbid condition of the brain and nerves and the latter from some other disease, or from irritation. Children are subject to both kinds & most of the diseases of children may be expected when they prove mortal to terminate in convulsions The causes of symptomatic convulsions are as various as the agent capable of producing irritation though the causes of convulsions in one child will not necessarily produce them in another. The susceptibility to them varies with the age of the child and the peculiarity and degree of delicacy of the constitution. Convulsions may arise from the sudden suppression of evacuations to which the system has become habituated. Irritation from teething is a very common cause. Worms in the alimentary canal may excite convulsions. But perhaps the most frequent cause is the presence of indigestible substances in the primae viae. irritating the nerves of the stomach & through them those of the whole system. Over distention of the stomach, even with food of a healthy quality interrupt the progress of digestion & the food undergoing action [illegible] fermentation “Or the excessive quantity of food may produce convulsions from the mere stimulus of distention” “Dyspepsia is a cause” This is an important maxim in the first children of young mothers Their anxiety of mind will often affect their milk 91 in the stomach, becomes noxious matter & excites convulsions In the season of fruit we may always suspect this as a cause in children old enough to eat it. Calomel has been known to be so irritating to the system as to bring on convulsions Costiveness also is a cause of convulsions in children A change in the quality of the milk of the mother or nurse, produced by improper food or by strong affections of the mind, in some instances is the cause of convulsions in young children. Hence not only the diet of nurses should be regulated, but their minds kept tranquil. It may be observed also that the countenance of the mother or nurse as also those of the bystanders has more influence upon children than is commonly supposed. Even a child but 3 weeks old, will be strongly affected. In some families there is said to be an hereditary predisposition to convulsion among the children. For the treatment we have two indications 1st to remove the exciting cause where this is local & 2nd to relieve the irritation of the system 1st We must enquire into the causes with with care. If evacuations are found to have suddenly ceased they must be restored. The guns should be lanced. Anthelmintics should be given if there are worms If improper food is suspected we must be particular in our enquiries, or we may be misled by a [vague] & general answer. When the convulsions have been brought on by improper food or by food in large quantities recently taken the stomach should be evacuated by an emetic of 5 or 6 grs 4 to 8 of sulph of zinc or of ipecac. # How long should we wait after giving one cathartic before we try another? the child being in convulsions all the while? The equilization of temperature will do a great deal to remove convulsive action Besides the soothing of the [nerves] etrc. Some rely on one and [illegible] or another Oil of a amber is not in my opinion better than many others The oil of amber apparently is the [illegible] the oil of [capal] brought from its E. [illegible] It is recommended to dissolve the oxyg oil in [illegible] [but] it is slow of solution It dissolves readily in either 92 If the offending substances have probably passed the stomach & the irritation is in the bowels, these must be evacuated as speedily as possible giving and injection to begin with [illegible] it to [illegible] cathartic. Sometime it will perhaps be best to give a dose of calomel large enough as to operate both as an emetic & cathartic. Frequently large & repeated doses of cathartics will be needed in order to overcome the torpor produced by an excessive quantity of food. The food also diminishes the cathartic operation is the case with the French [dinner] pill. We may give calomel, 5 to 10 grs. or scammony 3 to 4 gr. jalap 2 to 3 gr. senna & manna, castor oil, neutral salts etc. If dry cathartics fail to produce the desired effect, the liquid should be tried. Sometimes will be acted on by one kind when they will not by the other # If one fails after 3 doses try another & assist with injections Begin with cal. & follow with the others 2. If the convulsions continue after the removal of the cause we must rely upon antispasmodics or even at the commencement. Of these the warm bath must be considered the most powerful remedy in convulsions of children always [illegible] & often efficacious. Its influence is immediate and extensive. Antispasmodics, as pearl ashes or aromatic herbs, may be put in to the water of the bath Of antispasmodic articles a great variety are used. Oil of amber Dr Rush called his sheet anchor in spasmodic diseases. It is useful internally, and applied as an external irritant along the spine. The artificial musk a preparation of amber is in my opinion a better article than amber itself, for all cases where amber is “# Seneca oil is more limpid & pure & approaches nearer to naphtha” Soot is a [illegible] Soot is efficient as a nervine tonic & deobstruent It is sometimes very efficacious in jaundice & dyspepsia It was very popular in Philadelphia with ashes for stomach complaints “The British oil is manufactured in this country from Barbadoes ter & spts turpentine” The nostrils may be rubbed & it may be given internally “also rubbed on the skin” Though so offensive to the small yet children taking the tinct readily potash [illegible] & [illegible] All the alkalies & alkaline earths are antispasmodic. They are not nervine properly. There yet seems to be abundant testimony to their antispasmodic properties. They are to a certain degree tonics. i.e. they have a specific action on the mucus membranes. I have maintained [illegible] they operated by generating excitability a view supported by Jobe vide Hufeland’s Journal in Lond. Med. & Phys. 93 indicated. The mineral oils from whatever source obtained, such as petroleum, seneca oil, British oil, are little inferior to the oil of amber I prefer the seneca oil 5 to 30 drops #. The eympreumatic oils are useful antispasmodic and soot is often given by nurses in decoction Ammoniae in any form is a good antispasmodic A solution of ammonia in spirits often contains an empyreumatic oil of this solution we may give to a child from 2 to 6 drops in an ounce of water. Either the spirt, the carbonate or the aqua ammoniae will be useful in alleviating spasms in children either applied to the nostrils, rubbed upon the skin or given internally. Dippel’s animal oil, a very fetid substance distilled from bones in a state of putrefaction owes to antispasmodic virtue to the presence of ammonia. It is too disgusting Castor and valerian are good articles of this class, but in cases of children they are too bulky & a sufficient quantity cannot be introduced into the stomach. A more powerful article than these is the asafoetida fetid gum 10 or 20 40 drops of the tincture. This is a very valuable remedy to give by injection using for this purpose either the tincture zii or a decoction all the alkalies are antispasmodic & are proper for children. The most powerful is pearlash given by injection, zi to zii in lbis of water I have seen more sudden and permanent effects in cases of spasm produced by injection of this kind, than by any other remedy. It has been successful in cases both of In for [illegible] who have [resumed] in convulsion 2 or 3 days when a variety of narcotics had been given. I have seen surprising effects produced by the injection These applications sometimes fail & we cannot tell to what sort of cases they are Yet we must have a variety of resources if we would be able practitioners Opium is powerful, but though it frequently relieves, yet it sometimes aggravates the symptoms I have given it with great success in paroxysmal convulsions anticipating the paroxysms yet in these it will sometimes fail 94 infants and of adults. Sometimes however this remedy fails & I am not able to point out in what particular “We are compelled sometime to practice [illegible]” instances it is indicated. All the narcotics are antispasmodic. Opium is a powerful antispasmodic and may be given to patients of any age when the condition of the system does not contraindicate it vid. lect on m. m I have given opium where the convulsions were violent & returned at stated periods with fever preceding. When the convulsions appear at regular intervals, as once in an hour, or day, opium in repeated doses may be considered a specific. Counter irritation may be valuable adjuvant in the treatment of convulsions. Oil of [origanum] & similar articles may be rubbed along the spine drafts may be applied to the feet and wrists & mustard horse radish leaves etc. to the abdomen. When the convulsions are frequently repeated in children and become in any degree periodical, a cathartic of calomel given once or twice a week, rarely fails to prevent their recurrence. If this fails I give stramonium or other narcotics If convulsions arise from organic affections we can expect to effect more than to palliate instead of curing the disease. “Counterirritation by mustard, horseradish etc. may be useful” An injection can do no harm can always be administered and if one cannot administer articles by the mouth Irritants may be applied immediately e.g. mustard horseradish garlic N.B. we do not need powerful vesication for the tender skin of infants. Even garlic sometimes vesicates Ammoniae to nostrils & in mouth Be sure that you have [water] enough to [illegible] the child completely for the nerves are apt to think that it is sufficient to half [illegible] child & then sprinkle or scatter water over producing an equal excitement Friction may be applied while in the bath & after coming out [illegible] with dry flannel If the irritants have been applied before the bath taken then off when [illegible] about to immerse in the bath & put them on again if necessary after coming out If the child seems to be in a state of asphyxia the emetic may not take effect; then irritate the fauces the child being lard on its abdomen supported by the hand of the nurse 95 When you are called to a child in convulsions, without previous sickness, direct an injection to be immediately administered and the warm bath to be prepared. if the injection does not relieve, put the child in the warm bath previously adding pearl ash in proportion of zfs to a gall. of water. Let the child remain from 5 to 15 minutes taking it out when it begins to grow exhausted. When taken out of the bath let it be wrapped in flannel & put into a warm bed. Then apply irritants as mustard, horseradish garlic, or aqua ammonia to the abdomen feet and wrists Apply aqua ammonia to the nostrils and temples As soon as the child can swallow give a dose of calomel; If the countenance is pale or livid the cause may be suspected to be some offending matter in the stomach & an emetic ipecac not [illegible] generally should be given. We may often succeed in exciting vomiting by irritating the throat with the finger or a feather & this method should be tried when the patient cannot swallow & is known to have taken improper food or when it is desirable to hasten the operation of an emetic. The child will vomit with much more ease if it is held lying with its belly upon the nurses’ hand, which this supports the abdominal muscles If the child is much agitated at the sight of the water which it is to be immersed, let the tub be covered with a blanket & the patient gradually lowered into the water there will then be no difficulty 96 Epileptic fits are very frequent among children Epilepsy is defined by Good A “spasmodic agitation & distortion, chiefly of the muscles of the face; without sensation or consciousness; recurring at periods more or less regular.” One side is generally more affected than the opposite The limbs may be fixed and rigid with twitching of particular parts. The pupils may be contracted or dilated & the attack may be followed by coma. The attack may be abrupt and without warming or may be preceded by hilarity, or a giddiness or other unpleasant sensation. Sometimes there is what is called the Aura epileptica, a sort of formication, creeping up the body for which the ligature may be applied The fits may be kept up by the constant presence of the cause such as malformation of the brain etc. or, by habit & while in the former case the disease will be incurable, in the latter habit will be very difficult to break up. The causes of epilepsy may be, malformation of the brain tumours of the brain derangement of the system produced before birth by syphilis & rickets or the same causes as those which produce the rickets & in children oftener than after preventing the disease may also arise though more rarely from mere excessive irritability of the system, even’ without any exciting cause of irritation such as indigestible substances in the alimentary canal or suppressed evacuations Among children however epileptic fits are most commonly excited by teething, suppressed evacuations & the irritation of a morbid condition of the bowels or of In scrophulous children remedies for scrofula may be given. [illegible] rickets I have often found advantage from blisters behind the [ears] I have found the cath mode of treat successful for children within the year especially calomel In some cases the most powerful cathartics are required If there is acidity of the passages so that cal. seems to gripe much [illegible] chalk any quantity from 5 to 10 It is immaterial whether the action is chem. or certainly the effect is good The system being very irritable ordinary stimuli or rather a little more than ordinary brings on [illegible] Hence improper articles improper exertions of mind & body etc. Careful management & [illegible] 97 indigestible substances in them. The treatment of epilepsy must vary with the causes which produce it but does not differ materially in the case of children from that of convulsion fits In epilepsy from rickets I have used the cold bath with advantage. In children our attention in the treatment of epilepsy must more especially be directed to the alimentary canal. Cathartics are far more valuable with them than for adults. I have almost always succeeded by means of a course of mild cathartics & joined with one of tonics, such as the tonic solution & the different preparation of iron When called to an attack brought on by offending matter in the stomach and bowels, we should commence the treatment with a strong cathartic in order to thoroughly clear the alimentary canal calomel is the best article but if the bowels are loaded with mucus so that calomel fails to operate we may conjoin 1 or 2 gr. of gamboge & of scammony & 5 of jalap & this though powerful, will yet operate kindly. In the subsequent treatment calomel should be given 3 or 4 times a week; though if there is a deficiency of mucus in the bowels an abrasion as it were the blue pill will be preferable or chalk may be conjoined. Among infants most cases are curable by careful management, both of the physician of nurse The diet should be regulated with great care Generally however there is a morbid appetite, & a sub-[insanity] There is often a difficult, particular waywardness [illegible] like into [illegible] etc. In children more than a year old I have given stramonium so far as to dilate the pupils keeping the child under the operation of it I have not prescribed it to children under 2 yrs or 18 m. I recollect one case in which the convulsion begun to subside as soon as the pupils began to dilate I would not prescribe to [illegible] but to [all] symptoms e.g. tonics all the nat. ton. tinc irr. cap. lead I would give the lead where cathartics, from the excessive irritability of the al. can. aggravate all the symptoms Lead will produce a torpor or sub paresis contrary to this Narcotics also will meet this condition Opium will occasionally, but not generally Why it is we know not but the fact is that phys. do not depend on [illegible] ep. seems to cause a determination to the head 98 with regard to food. This subderangement of the mind manifests itself also in other ways by oddity of appearance gesture & action. A strange propensity for climbing for instance is met with & epileptic children will often be so active & so artful as to be very difficult to manage For more particular treatment see my lecture on m. medical articles stramonium & nit. silver [illegible] turpentine from 10 gtts to zi diluted stramonium, camphor, opium atropa belladonna & most of the more powerful narcotics Arsenic zinc is one of the best of the metallic tonics Actual cautery, [moxa] etc. have been highly extolled “In epilepsy caused by rickets or by the same causes as those which produce ricketts. I have used the cold bath with advantage” “Mercurials followed by mild cathartics [Seontod??] etc.” The child will be still breathing languidly The parents think it dead If you look at it carefully you will perceive as languid treating & looking at the eyes you will often perceive a little convulsive motions of the balls pulse not much disturbed The child continues a few [illegible] with paroxysm & comes out with a scream like an adult from nightmare Not dangerous In a few instances [somerset] Case adult patient [illegible] a chair stands fixed eyes fixed come out with a stare irritable & sub derangement for a few days Afterwards [somersets] “asleep once a sleep twice” Case a girl last year gather up [illegible] [somerset], even 50 times than cataleptic then exhausted This case changed from chorea to catalepsy Repeated bleedings did not change the emaciation etc. 99 Catalepsy This affection when it affects children, is called in poular language still convulsions. It is a very rare disease among adults, but among children I have met with several cases of it In catalepsy the muscles are universally or partially affected with a tonic spasm. The patient remains fixed in the position in which it happened to be when seized appears asleep, is insensible and scarcely breathes. The eyes are commonly fixed, but sometimes have a little motion. The paroxysm may terminate with common convulsions. The length of the paroxysms I have known vary from a few minutes to three hours & in some cases they are frequently repeated The disease arises from the same causes in general & requires the same treatment as epilepsy & convulsions. Cataleptic convulsions sometimes follow other convulsions & in some instances have been brought on by drastic cathartics In adults catalepsy is often followed by irritability & a degree of mental derangement. “Catalepsy arises from the same causes and requires the same treatment as epilepsy chiefly by cath. & antispasm. Sometimes children are affected with catalepsy without it being observed When I commenced practice I thought the notion of still convulsions a mere whim” Dancing before the [illegible] of St. Vitus Dance [illegible] 3 or 4 well persons Comes on gradually parents complain that their children are getting into bad habits Awkward motions The dis. is not benefit. by [illegible] I recollect a gentlem. 40 or 50 yrs told me he had chorea when a child & recollects perfectly the indignation, horror & disgust when so long as to be unable to speak [illegible] Hand carried not to the mouth Sometimes the motions finally become regular “The dancing master” feet blind [illegible] then hands then body then stop like a statue then begin one foot like a [falling] [illegible] 100 Chorea Sancti Viti This is a disease not to be mistaken in its ordinary appearance the voluntary muscles are but partially subject to the well and their motion is convulsive. It occurs oftenest in females of relaxed habit & about the age of puberty especially if they have grown rapidly or been much confined to the needle or to study. In children this disease is often caused by irritation in the primae viae Chorea also arises in some cases from a peculiar irritability of the system in which ordinary stimuli produce convulsive action This irritability may be accompanied with relaxation, or with increased action together with a determination to the head. Indeed it is said sometimes to be connected with inflammation of the brain & hydrocephalus. With those who are predisposed to this disease, particularly if they are females about the age of puberty affections of the mind may bring it or epilepsy sometimes runs into chorea, or alternates with it. Finally, the disease may come on in a very gradual manner, so as not to be suspected, causing a strangeness in the gestures walk etc. which at first is attributed by the friends to the formation of bad habits. This disease is rarely fatal and is not difficult to cure in patients under the age of puberty after that period it is seldom cured. When the disease is of long continuance a great variety of remedies are generally “When I give cathartics in chorea it is not for the evacuation but to produce a new action. All cath. will not act favorably. Hamilton’s views in prescribing cath. are not generally correct.” There sometimes irritation of al. can. from accumulation of feces about the coecum. Hence Hamilton’s plan of purgatives Purgatives will cure but [general] by impression on system It is said to arise from a tonic infl. of brain I have read periodicals have not so I have seen all kinds of treatment tonics, cath narcot. electric. galvan. cold bath etc. etc. Perhaps no disease prescribed for more [illegible] periodically We find one and another article fails and are obliged to go the whole [illegible] off [illegible] narcotic etc. # “In one case of chorea I tried the arnica until the head became affected. The patient began with a decoction of zii the flowers & increased to zfs without any abatement of the disease” Prof T’s [illegible] [illegible] Nux vomica has been used with success in many cases but there are other narcotics which act more powerfully & more certainly I have not used it deterred by [Ba??] [Surrey] who found it injurious for some convulsive cases “Stramonium succeeded in a case following epilepsy” 101 tried and the one last given is apt to be considered as having effected the cure; but I am inclined to think that in many of these cases the disease instead of being cut short by the treatment and run its course and then ceased of itself The most common indications are [for] narcotics and tonics with antispasmodics as palliatives & permanent counterirritation along the spine in some cases. In children however cathartics are commonly indicated; though in general the plan of treating chorea by cathartics, has not succeeded very well in my practice. Dr Hamilton however depended upon cathartics and had better success, though it may be remarked that those who act on that treatment are also the metallic [illegible] When there are symptoms are symptoms of worms, of hydrocephalus, or of inflammation, of the brain or when the disease follows epilepsy we must treat as for those diseases; & if it the chorea is the result exclusively of the peculiar irritability above alluded to, narcotics must be our chief dependance. The principal articles which I have employed in my practice are conium, conium & iron sulphate of zinc, sulphate of iron & other metallic tonics. Various narcotics are used, as the nux vomica in doses of 1 or 2 grs of the seed in pill or 15 or 20 drops of the alcoholic tincture; and antispasmodics as valerian musk etc. may be used as palliatives Cullen’s favorite tonic was the ammoniuret of copper 1 to 4 gr. I have lately used it with advantage in pill 2-3 hours in creasing other tonics are mineral acids, nitrate of silver, bark & the arnica montana #, which is a narcotic & tonic & was successfully used by Dr [Monsen] in chorea” Dr. T’s copy [M. ?] “Sulph zinc 1 gr. may be given 3 or 4 times a day nit. sil. 1/6 to ¼ gr. succeeds best in relaxation of the blood-vessels” “Evacuate the first passages and restore the healthy secretions & irritability of the system by tonics & antispasmodic “I have rarely effected a cure by cathartics though I generally begin with them The cure with antisp. & tonic is slow 2-3 [illegible] with narcotics more speedy but uncertain” A good deal may depend upon the careful management of the patient keeping him quiet & amusing him especially avoiding the irritation of the [pressure] and the impertinent curiosity of strangers The young man in a debilitated “So camphor has sometimes been given in mania to such an extend as to produce epilepsy & sub-apoplexy & this sometimes cures the mania” 103 double the quantity, when the head began to be affected still there was no considerable relief The patient was finally cured by taking the bark in substance zi a day. One case which came on in the gradual manner above described & was brought to a high degree by a dysentery proceeded so far at least as to present the peculiar symptoms of hydrophobia such as horror of water etc. convulsives perfectly [like] that frothing of the mouth etc. died in coma exhausted narcotics tonics etc. no effect excitability exhausted by [illegible] This disease may affect the mind causing it to run upon particular subjects especially upon that of numbers & calculation. I once travelled a short time with a book pedlar who had the odd gestures of chorea & had also this facility in calculation, being in this respect fully equal to the famous [Serah] [Colbourn] [Serah] [Colbourn] though furnished in Europe with the best advantages for education never improved and this result I ventured to predict, when I first heard that he was to be educated. I have seen several such cases. # They have a peculiar articulation & expression of countenance; and are deficient in memory and judgment. Vide [illegible] 12 [illegible] for [Serah] [Colbourn] Case girl at stool good talents studied hard [stand] out of schools [illegible] Cal. narc. cath. tonics operated but [Elateri.] 1/16 gr. once 4 hr in about 24 hours deadly sick nausea prostration vom. purg. disease broken up. It may be diff. to class this A year after similar causes brought on a second attack # Connected with acidity gives great pain not dangerous “This is a troublesome and not unfrequent complaint, arising often from improper food and that stab of the stomach which causes acidity. In a torpid state of the stomach when the healthy action ceases or is feeble, chemical action commences, and the acetous or putrefactive fermentation, prevails according to the contents of the stomach” “If our remedy fails try another for there are no two exactly alike & the judicious physician will discriminate as they are indicated” Among the astringents should be mentioned the rose willow It is one of the pleasantest astringents & is a popular remedy in canker It seems to combine a mucilage Almost any of our wild willows may be used Nitrate of silver may be used It is often however difficult to touch the ulcers and we may then use astringent washes. Rhus glabra and R [typhina] are good astringents vide hosp. [illegible] sub. [illegible] The poison of R [vernex] I have more than once known communicated in more than one instances by using the wood as fuel. I recollect a man’s [illegible] to me on account of an eruption on his legs. I told him he was poisoned. He replied that there could be no cause for it but a pair of the pantaloons lately dyed black. Upon investigation I found that the poison species of sumack had been used by the dyer by mistake for the common one. Young persons are more 102 Cold bathing is sometimes advantageous tepid is seldom proper Electricity has been used. I have seen little benefit from it Setons, issues, tartartar emetic ointment along the spine & other modes of counterirritation, are employed & may be advantageous but where the irritability is great they do injury If the disease is not translatable it is made worse by counterirritation In the treatment of patients affected with this disease, we should bear in mind, that they are the subjects of great mental sensitiveness & irritability The presence of strangers in injurious & the remarks of bystanders upon the patient may cause an amount of mental irritation little suspected. I have succeeded in curing chorea by elaterium though this is an article not mentioned by writers as applicable to this disease. A young man debilitated by confinement as a clerk in N. York was thrown into convulsions and derangement of mind, by a sight of distress while on board the packet for this place Elaterium was given to prostrate the system & break up the habit. It was successful & this led to its employment in chorea. I have completely broken up the latter disease by an eighth of a grain of elaterium & this is the only case which I have broken up vide end of this article Case a female delicate 14 yrs of age had not menstruated had been treated with cathartics, epispasmodics and narcotics, which palliated the symptom. The patient then took arnica for 10 or 12 days beginning with moderate doses (zii to a pint of boiling water being given in 24 hours) & increasing to I have found [illegible] which however was Dr [Rush’s] favorite remedy in females about the cessation of the [illegible] useful Friction antispas. electricity etc. had merely palliated The case then [illegible] to indicate tonics [illegible] the other remedies had [illegible] effect or not recovery rapidly upon bark Sometimes connected with pneumonic affected or with [organic] eff. of the heart In some of these cases [illegible] of copper 1 to 3 gr. rarely more than 2 gr. nauseating article [illegible] in such cases more especially As the [disease] advances sometimes [illegilble] difficult [illegible] swallowing dark [tongue] # [illegible] of them the book pedlar and [Minot] [Sheri] [illegible] [illegible] Both these had this facility in [calculating] # At this time there was not excitability enough left to enable the elat. treat. El. shd not be cont. more than 103:a Ulceration of the mouth in children This is sometimes a troublesome complaint and one that does not readily yield to remedies. It is commonly called canker. The complaint consists of one or more ulcers, which commence with an inflamed point or with a white slough situated commonly near the frenum but sometimes extending over the whole inside of the mouth. The edges of the ulcers are inflamed & elevated & their surfaces excavated, as if they had been eaten out with caustic. The child drools much and nursing is evidently very painful to it. A febricula attends the first stage. The bowels are slow and digestion not vigorous indeed the complaint often arises from improper food and is connected with that state of the stomach which causes acidity Treatment. First excite action of the bowels by magnesia, if there is acidity, blue pill, if there is torpor, or calomel grii & chalk grvi. After this give tonics & astringents as Moseley’s tonic solution 3 to 12 2 to 10 gtts 4 to 6 brak compound tinct. vitriol 4 to 5 gtts & the vegetable astringents as geranium in a [ter] spoonful of water statici spriaea cornus etc. a little laudanum may be added For topical applications we may use the vegetable astringents just mentioned, catechu, kino etc. or the following which has been recommended as very efficacious RX sulph. cupri grs x, cort. peruv. zii acad. gum zi mellis et aquae aa zii make a soft paste to be applied to the ulcers with a pencil. A weak wash of corrosive sublimate may be used Sometimes a mild caustic is serviceable, as nitrate of silver A wash of opium or of opium & corr. sub. is sometimes the best viola pedata makes a valuable wash. Asclepias tuberosa is escharotic. [Post] [illegible] case affected by this poison than old. When young I have often been poisoned myself by boing near the plant merely. Now I can brush past it with impunity provided it does not touch my hands or face. Some persons are not affected at all. The uncertainty of its operation is the only reason why it is not used in medicine. Corrosive sublimate is a good application for the affection of the skin. Yet the disease is a specific one and must generate run through its regular course. A similar disease is produced by the oil of the shell? of the cashew nut Ulceration of the mouth continued “The disease sometimes attended with severe pains, as severe as in tooth ach in which case opium is serviceable. Case of an adult use veg. astring. copper, zinc, opium, nit. silv. & at last corros. sublimate. This last would not be safe in the case of children. Intense pain was produced, which was remedied by holding it in the mouth There was a profuse salivation but it soon ceased and the disease was entirely removed. The surface of the ulcer was destroyed by the sub. & the dis. being local this effected a cure # I have turned my attention particularly to the question whether cal. produces it. I have known the dis. to allow dysentery It was an old notion that cal. broke down the crasus of the blood and it produced a tendency to gangrene. But in the venereal wards of hospitals you will see patients with sloughs all over the mouths and yet no gangrene 104 Gangrene of the mouth This is not a primary disease but a termination of other diseases making its appearance soon after their abatement I have known it follow dysentery and other affections of the bowels, but not any disease in which the blood vessels have exhibited an inflammatory action. It seems to follow diseases of the nerves rather than of the vascular system Children are generally subject of it. This disease is sometimes accompanied with much pain & at others with none ordinarily with little or more. One of the first symptoms is a constant inclination in the child to pick some part of the mouth with the fingers where the gangrene first commences either the teeth gums, less or cheek That part becomes spongy & has a fungous appearance in the course of a few days discharges a [illegible] matter, has a livid appearance & finally becomes black and dry the adjoining parts of the face become tumefied and indurated and the disease continues until a considerable part of the face becomes completely [sphacelated] when the patient dies It may continue sphacelatal in [illegible] etc. the sphacelus being hard dry & black like a piece of leather This disease has been attributed to the use of calomel, but it is entirely unlike that produced by this article, and occurs also in cases where no calomel has been given. # In those cases where calomel has been freely given the disease is not so apt to occur vide case 4th I have known a similar affection occur in the leg of a child, & an irritative fever preceded by rheumatism. Commencing with a spongy and orange coloured spot which afterwards become hard & black, the gangrene livid purpled as though the blood had settled pulse small not much disturbance of the circ. syst. except that it was large # & Prof. Smith & myself could not get down much medicine and were obliged to [illegible] [illegible] with external applications We [illegible] injections and a great variety of external application blisters “When the disease appears with tumefaction I think leeches might be of service. This was called by Dr Smith congestive inflammation. In other cases of gangrene, leeches would not be of service It is not easy to [class] the operation of charcoal It has been called a tonic, but it does not much resemble peruv. bark and we do not gain much by classing it with it It seems to act by generating an excitability Charcoal shd be made of soft wood or of lamp black burned over again in crucible, as is sometimes done by the apothecaries 105 extended up the leg and the child above the knees on both sides died [illegible] No applications seemed to have any effect. The child was irritable & The disease under consideration is nearly allied to that called swelled tongue, but the latter oftener attacks quadrupeds The treatment should be stimulant & antiseptic. Acrids as capsicum may be used & the arum triphyllum accidentally has been known to cure. In one case which I shall relate charcoal appears to have effected the cure. Case 1st The first patient that I saw affected with gangrene of the mouth was an adult female who had the typhus fever. The gangrene commenced on the inside of the cheek & when I first visited the patient a portion of the cheek as large as a dollar had sloughed off out? Great part of the food taken into the mouth passed out at the hole in the cheek. The patient continued in this state for eight or ten days & then died The attending physicians informed me that she has received the ordinary treatment for typhus fever. Case 2nd The next patient affected in a similar manner was a girl seven years of age. Previous to the gangrenous affection she had had a most excruciating disease, which affected the knees legs and bowels I have called it nervous rheumatism & shall notice it in another place. For this she had taken large doses of purgatives 106 calomel & opium, with diaphoretics & tonics. In three or four days the pain ceased and the fever almost entirely disappeared. The guns presented no symptoms of salivation & there was no increase of saliva. In five or six days after the fever subsided the patient complained of severe pain situated in the right temple & extending down to the shoulder like that which had been in the extremities. This was removed by opium to complain of the teeth Soon after she began to work at the molar teeth of the upper jaw, on the right side, at the same time she had a cough which was accompanied with an expectoration of white viscid mucus, and the breath became very offensive, resembling the effluvia of an anatomical room where subjects have been kept a long time. The appetite was tolerable, however the patient took animal food, with relish, and the bowels were easily moved with a little rhubarb the patient world at the teeth until she had removed two of the molar teeth with her fingers, she still continued to pick at the gums. The cheek of the side affected became hard, swollen & red. In forty eight hours a black spot appeared in the centre of the swelling. This spot the patient immediately began to rub with her fingers & soon made a hole through her cheek. The gangrene continued to extend, for a week & at the end of that period had proceeded as far back as the angle of the jaw affected the throat & perhaps the aesophagus The patient then died, having taken food and medicine will until within forty eight hours of her death. 107 Peruvian and oak bark, opium & camphor were very freely given the affected side of the mouth between the teeth & the cheek was filled with superfine bark & poultices of bark were applied to the face In the last stage affected perhaps the lungs Case 3rd Another case occurred in [illegible] subject a child etc. A female child, about 5 years of age was attacked, in the winter of 1813 with “constipation with fever” the complaint being principally confined to the bowels The attending physician gave a dose of calomel and worked it off with senna and manna. A considerable quantity of matter was discharged from the bowels, but from its appearance further evacuations were deemed necessary, and several doses of castor oil were given. On the fourth day I was invited to see the patient. I found her with considerable fever of the typhoid grade, attended with pain in the bowels and head. There was also some swelling of one cheek & the child complained of one or two of the double teeth of the upper jaw on that side. These she frequently attempted to pull out with her fingers & finally succeeded in extracting one of them The cheek afterwards became swollen, inflamed, and hard to the touch & in a short time an orange coloured spot, appeared, upon the outside near the centre, which soon became livid, and the gangrene spreading rapidly, the child died, in eight days from my first visit. She became delirious previously to the cheek becoming livid & afterwards, was comatose. In this case the disease seemed to affect the brain as it does in some cases Bark, opium and camphor were truly given & antiseptic 108 poultice applied to the face as bark [illegible] [fermenting] [poultice] Prof. Smith saw this patient soon after my first visit & agreed with me in the opinion that the case would terminate fatally. He informed me that he had seen but one case of the kind before & that he had attributed that case to an injudicious use of calomel After seeing this patient however, he considered his former opinion as incorrect since in this case there were no marks of the effects of calomel & there was no probability that the single dose of calomel, given in the commencement of the illness, could have produced such an effect, especially when repeated doses of other cathartics, had subsequently been given & had operated freely 4th Case. The next case which I met with was that of a female 12 or 13 years of age, who had the dysentery, in the summer of 1815, accompanied with much typhoid fever & rather a larger discharge of blood by stool than is common in dysentery. The child had been sick for some days before a physician was called. I did not succeed in my attempts to determine the diseased action from the bowels to the surface by diaphoretics & the warm bath, & the disease ran its course and nearly exhausted the patient When it began to decline, the stools to present a fecal appearance & the appetite to return, the friends were There had been some aphthae and I was on a careful watch 109 much encouraged I, however, began to expect a fatal result for I observed, between the anterior incisors of the lower jaw, a fungous enlargement of the gum, the apex of merely a slight discoloration [illegible] & swollen between two teeth which had a purplish appearance somewhat as appears in salivation sometimes. I apprehended gangrene in the case (perhaps from the countenance) and on the first symptoms of it informed the parents, who however, could see nothing alarming in the small swelling between two of the front teeth. I began early with oak & peruvian bark, and at the same time gave freely of brandy and porter. As this course had no effect I applied bark and diluted sulphuric acid to the part affected & also covered with the lunar caustic. Still the treatment had no good effect the gangrene extended under lip and chin became black and the child died Case 5th A child about 3 yrs of age cousin of the previous one [illegible] had a dysentery, in the summer of 1815 [illegible] as there was another member of the family sick in oil uncommon & interesting manner viz the case of chorea resembling hydrophobia was much neglected Her fever was typhoid & the stools sometimes bloody and sometimes of a green mucus. After a course of 15 days and amendment in the symptoms took place the stools became less bloody, the green stools more rare & though the patient was extremely weak but no reduced low as the previous one, the appetite returne After convalescing gradually for six or eight days, there came on a samous discharge from the nose, small in quantity but very fetid which reminded me of gangrene # In this case I examined the gums to see if there was any appearance of salivation and found the gums etc. Two teeth and a piece of the alveolar process came out The disease did not spread so rapidly as the other ones In addition to bark, tonic solution etc. I gave charcoal 110 of the mouth which I had not been on the look out for AT this period the patient inclined to keep her fingers I her mouth. # The gums were very clear and bright & adhered firmly to the teeth, except on the left side of the upper jaw, where the gums of the biscupides appeared discolored and discharged a samous matter. I declared the parents that in my opinion the case would terminate fatally. The child complained of pain in the face and teeth. The cheek opposite the teeth became swelled and hard and of an orange colour. I declared to the friends that mortification had taken place 7 pointed to a black spot on that cheek which happened however to be accidental. I was mistaken for the next day it was found that the black spot was produced by a piece of burnt apple skin, which was washed off This encouraged the friends; yet within 24 hours sphacelus took place the apple skin was in the very spot where I had supposed that I had seen it. This gangrene ceased to spread after the spot became as large as the end of the little finger A circular piece sloughed out and left a hole in through the cheek of about a quarter of an inch diameter The disease abated, the affected teeth and a piece of the alveolar process came away the lips of the wound produced by the sphacelus healed up & the child recovered I recommended the same treatment in this case as in the preceding, but having no confidence in it, & abandoned it and gave charcoal to the amount of perhaps a pound or a pound & a half a day I h ad pudding made of half charcoal & half flour, sweetened with molasses & sugar & fed to the child for the appetite was good. Tonic solution When the disease commences of itself # At the time when the disease called the scalled tongue was very prevalent affecting cattle principally with swelling of the tongue & salivation but to some extent human beings with swelling of tongue cheeks etc. It was found that acrids as [arum] were the best remedies pulse 120 tongue then [brown] fur, considerable pain 111 and compd tinct. vitr. were also given & I commenced the treatment with white oak & peruvian barks & yeast poultice. I attribute the cure, however, to charcoal. Case 6th This was an idiopathic affection. Martha Denison a delicate constitution about 12 yrs of age was attacked in 1819 with symptoms of gangrene of the mouth. There was severe pain in the teeth and jaws oppression at the stomach and symptoms of fever. I discovered the purplish spot in the cheek & “the gums soon put on a spongy appearance” In this case I commenced the treatment with an emetic, which operated favorably I gave it to [illegible] the excitability of the system & gave relief. I then gave stimulants, bark, brandy & opium & kept in the mouth between the gums and cheek a paste made of powdered bark wet with brandy and laudanum. The patient recovered, but the two front teeth of the lower jaw became very loose and there was occasional pain & suppuration for nearly a year. It was about a year before the teeth became firm. [Superfine] bark was occasionally used. Case 7th In 1820 I visited a black child in the last stages of this complaint. At the time when I saw it, it could not swallow. It lived however in this situation for several days I have seen several children in the latter stages Even if there is no chance for a cure it si desirable to be able to give a correct prognosis Trouble has sometimes arisen from the opinion that such cases were produced by calomel A student of this school in [Litch.] cty from notes of my lectures It is known by an [illegible] swelling in the throat some fever etc. etc. In some seasons it prevails extensively & affects persons of all ages. In some seasons these diseases which are called contagious affects one description of persons in another another owing to mode of life etc. “It rarely affects a person the second time. It is said that if it affects the parotid of one side only it may occur again” I have treated cases of this disease with great anxiety. I have never known cases of greater irritation than from this disease “It is milder in children than in adults & is seldom translated to the mammae or testicles till after puberty” “Sometimes the swelling of the testicle is simultaneous with that of the parotid gland or [previous] I have seen several such cases” “The first symptom observed is sometimes a soreness of the testicles. They at length become 4 or 6 times their natural size a suspensory bandage will be necessary” “In some cases there arises suddenly, [illegible] pain in the head pulse full and tense eyes red & all symptoms of phrenitis” 112 Cynanche parotidea Mumps This disease is an inflammation of the parotid glands & is generally moderate in its symptoms Sometimes however it is translated to other parts & is then a severe disease endangering life. It is milder in youth than in adults & in general it is only after the age of puberty that it is translated. The parts to which it is translated occasionally, are the testicles & the prostate gland in males the mammae of females more rarely & sometimes the brain or stomach I have never myself seen a case in which the inflammation was transferred to the mammae but do not doubt the fact Sometimes it appears first in the testicle or at least simultaneously in that & the gland This disease has been considered contagious In my opinion it is not, but on the contrary is liable to be epidemic. When its prevailed in college, the students who left in order to avoid the contagion were attacked as early and is certainly as those who remained. I have noticed that it made its appearance pretty regularly once in seven or fourteen years The fever which accompanies the severer forms is either of the inflammatory or the typhus grade or may be merely irritative & should be treated accordingly When the testicles are affected they are painful swollen sometimes to an excessive degree & sometimes so highly inflamed as to indicate venesection When the stomach is affected “it puts on crythomatic inflammation” and there is hiccough, subsultus tendinum, irritability of stomach and frequent vomiting. # When the brain is affected there is pain of the head & eyes, with hard and tense pulse When the parotid glands only are affected the # These symptoms may come on after the affect of test. [illegible] continued, some [illegible] begin to subside. Dr Rush observes that applying a blister directly on the infl. prevents the system from being affected. I do think blisters keep the aff. in one part “In some seasons an emetic at the commencement or a blister will prevent a translation” Having [learned] the importance of attempting the breaking up of diseases I cast about one year for means to interrupt it & found emetics quite efficacious Stramonium After the testicles have been affected some time and the affection begins to subside the symptoms sometimes change There is subsultus tendinum the stomach become affected vomiting is frequent with hiccough etc. In this case apply mustard to the stomach & feet etc. 113 a generally mild and more inconvenient than painful A translation makes it worse; more so when the translation is to the stomach than to the testicles & most of all when to the brain. Sometimes the complaint is very severe, the fever lasts three or four weeks and the patients are many years in recovering from the disease Treatment. The disease is often broken up by an emetic in the commencement It is best to stop it in the first stages if possible. Mild applications to the inflamed parotids we generally sufficient, such as ammonia or volatile liniment. Dr Rush however recommends blisters to the parts affected, in order to prevent a translation. When the disease effects the testicles & give emetics and apply discutients to the local affection. I also apply blisters to the inside of the thighs. They relieve the testicles when they are swollen & prevent translation to the stomach For a discutient was we may take the following Rx mur. amm. ziii; camph zi; brandy or vinegar 1 gill; water 3 gills. When the inflammatory action is high, bleeding may be practised. It will be well also to use a suspensory bandage. If the stomach is affected in the manner above described we have a difficult case to manage. Epispastics must be applied to the scrotum, counterirritants to the epigastrium to ally vomiting, with effervescing mixtures internally for the Ether is best given in effervescing mixture (carb amm. & lemon juice) Carbon ac. makes stimulants more diffusible & hence causes them to be [used] gratefully and often to be well borne when otherwise the would not be Case 18 grs plethoric parot. gland & testicles swollen head affected Relieved by bleeding decidedly entonic the only entonic case which occurred In the progress of his case stom. became very irritable abdomen sore & tender excessive irritability Did not recover his health completely for years was left dyspeptic & with nervous irritability. To correct irritability of stom. lem. juice [illegible] is most grateful add [doses] of aromatics lime water also external blistering etc. Tonics or metallic tonics myrrh asafoetida (nervine also) hops lettuce These cases are so obstinate and will give you an opportunity to try a great variety of remedies cajeput oil on sugar ol. valerian Though the cases may be apparently alike yet you may find one article best for one & another for [another] A very distressing hiccup, accompanied with spasms might have been mentioned in connection with the vomiting give ether lavender cajeput oil also & valerian which are called terebinthinates 114 same purpose diffusible stimuli as ether given to rouse the system opium ipecac, as tonic stimulant, diaphoretic & nervine 7 finally to allay irritation of the system in general antispasmodics as castor & counterirritants to the extremities effervescing mixtures absorbents, also, as chalk & magnesia, cathartics cantheride & occasionally emetics may be indicated. When the brain becomes affected, the lancet should be freely used, cupping, leeches & blisters, applied to the head of the neutral salt given as cathartics Antimonials nit. [illegible] cal. & neutral salts # Some cases will require a vigorous antiphlogistic course of treatment, others with typhoid fever will require in the [illegible] a stimulating & supporting one, while others again will have symptoms of irritation chiefly & require a corresponding treatment In the progress of the disease uniform perspiration will be valuable Angostura serpentaria, qualified with cardamom or cubebs The old writers recommend also [contrayerva] I have much used it atonics of a peculiar character resembles much agrimonia eupatoria which I have used for it in the country where it is easily obtained the latter is non astringent # “Cold to the head and warmth to the feet avoid mental irritation recovery is usually speedy adults most liable to this translation” I consider [quinsy] an affection of the mucus membranes and [tonsils] nearly allied to catarrhal aff. There is a catarrh aff. nearly allied in which there is a thickening of the membrane. This diathesis may also run into croup Good classes angina maligna with quinsy Here is the evil of nosology For scarlet fever gradually runs into quinsy. We must have science and nosology but still we ought to know the errors which nosology is apt to lend [illegible] & the imperfection of science I have the advantage of not [illegible] having seen the disease but of having had it myself often [illegible] with an unpleasant sensation a relaxation a disposition to hawk and throw off [illegible] In this stage it may certainly be cured After the symptoms comes on swelling, or moderately succeeding to this a chill then swelling with pain perhaps extending to the [illegible] The tonsils enlarge The fever is considered enteric or a common but unless among the labouring men in the country it is more usually subacute One tonsil is perhaps more enlarged than the other perhaps one goes on to suppurate & the other becomes of the natural size and appearance The uvula and fauces swell and respiration and deglutition are prevented. Sometimes ulcers from at first upon the tonsils. Examine each case and do not be too positive in calling it quinsy for this & scarlet fever do blend These symptoms continue 2 to 36 or 48 hours I do not know that I have ever seen a fatal case of 115 Cynanche Tonsillaris Quinsy This diseases has been called “I include also under the term quinsy all effections of the upper part of the aesophagus and pharynx which resemble quinsy in their grade of action” Quinsy is an inflammation seated in the larynx glottis & fauces The characteristic symptoms is swelling of the tonsils Sometimes it is seated lower down in the pharynx than the tonsils, but this does not alter the nature of the disease In some cases it is complicated with catarrh. Those who have once had this disease are very liable to a return of it “The disease common at the age of puberty that before or after” Quinsy may be divided into two stages 1st Predisposing debility indicated by relaxation of the uvula and tonsil, irritation about the fauces, weak deglutition, general languor, with cold chills and uncommon sensibility to cold. This usually continues from 3 or 4 to 12 hours the progress of the disease being sometime rapid and sometimes slow 2nd As the disease advances we find, soreness, pain, redness and swelling of one or both of the tonsils & an inflammation of the mucous membrane of the pharynx; deglutition in exceedingly difficult; there is a severe cough & especially a spasmodic one upon taking food or drink, there is much heat about the throat and about the head & sometimes pain in the head, with a pulse so full and tense as to indicate bleeding. Sometimes there is an excruciating pain in the ear. “rarely cough unless complicated with catarrh” This stage may continue three or four 3 to 7 days days. It terminates either in resolution, or suppuration. of quinsy though I have seen many that I thought would prove fatal. I have known a patient continue unable to swallow for 3 days and yet recover When however it is in the form of swelled tongue it may prove fatal. “An entonic fever may attend, with fullness of pulse much headache excruciating pain extending to the ear; but for more commonly at least in my practice, the pulse is little affected, and the disease is almost not entirely local” # riding on horseback and having the snow melt on his throat & [conduct] off the [caloric] rapidly # and shd carry a piece of alum in the pocket “It is important to distinguish this disease from roseola (scarlet fever) There is an erythema of the fauces distinct from both which yet may terminate in either [illegible] The diagnosis is generally easy but there are cases where it is extremely difficult & indeed there is no definite line believed the two especially in the first stages We must bear in mind that quinsy is commonly more inflammatory that it is not apt to ulcerate & we must be guided somewhat by the prescribing epidemic 116 The suppuration is generally in the tonsils, but in some cases where the disease is seated lower down, a part of the aesophagus suppurates. “The tonsils often remain permanently enlarged” Causes. Quinsy occurs must often in the latter part of autumn & in winter. It is caused like catarrh by alternations of heat and cold by exposure to cold & especially by exposure to cold storms of rain or snow. # Sometimes it is connected with dyspepsia & it may be brought on by irritating substances, as acids, acting upon the mucous membrane of the stomach. I recollect a case of a young man who was attacked with a severe quinsy in consequence of drinking freely of cider made cold with ice Persons who are subject to quinsy should be very cautious about exposing themselves to the alternative of heat and cold # Diagnosis. This disease has sometimes been mistaken for scarlet fever. It is not difficult however to discriminate between them by attending to their prominent symptoms the quinsy being as inflammation of the mucous membrane etc. The first stages however of scarlet fever, resemble those of quinsy, and the difficulty of discriminating between them is at that period much greater. In deciding upon any particular case we must be governed by somewhat by the nature of the prevailing epidemics Chewing camphor will also but not so well break up quinsy in the forming stage but chewing this article is apt to produce pleasant symptoms in the stomach and head Other stimulating applications would probably answer as [guaiacum] & any alcoholic tincture “The prophylactic plan of carrying alum in the pocket etc. has succeeded in hundreds of cases. Indeed when called in the latter stages I often tall them I can do little except to prevent it in future” When the dis is fully formed and when there is much pain in the neck running up into the [illegible] fomentations and the vapour of warm water, the steam bath by throwing over the patients head a blanket and having a teapot of warm water A blister also in the above circumstances will relieve the pain and give great relief An emetic also will be often very beneficial in the commencement of the second stage There is often an excessive quantity of acid in the stomach Case A young man in very hot weather [illegible] a large quantity of cider made very cold with ice was taken at night with great pain and difficulty of swallowing The patient was very anxious to be cured that night A large quantity of tartar emetic was given in excessive doses until a severe orgasm was produced then seeing to [illegible] stricture of the upper orifice of the stomach the [illegible] & secreted from every pore from the violence of the action of the system finally he [illegible] away, and continue in syncope for 10 or 15 mins came out of his fainting fit, the tart. ant. acted as a cath. and the patient was entirely relieved of the difficulty of swallowing [illegible] was merely feeble and exhausted from the prostration of the [tart] 117 Treatment In the first or forming stage. Quinsy may be easily broken up by keeping a small piece of alum say of the size of half a pea in the mouth, and swallowing the saliva until the symptoms have left. Various other astringents may be useful in the first stage. I have given the astringent barks and bitter roots, catechu etc. & have also combined with them the mineral acids chlorine etc. “But all these things will be injurious in the 2nd stage” When the disease if farther advanced a more energetic treatment is necessary. If the tonsils are largely swelled astringents will merely aggravate. IN this stage it may often be broken up by a strong impression made by nausea and vomiting. A strong emetic 3 grs tartar emetic with 8 grs of ipecac # may be given & when the disease arises from a chronic affection of the mucous membrane & acidity of the stomach, an emetic will remove it. In one case I gave half a grain of tartar emetic once in 15 min. until the system was affected, I succeeded in conquering the disease. The patient was in extreme pain & exhausted he fainted previous to fainting he was unable to swallow after coming to, he could swallow & the disease was removed. “But if the case has advanced a little farther, emetic will do no good”s Gargles will in general do harm rather than good, where there is much inflammation. If the irritability is extreme mucilages may be given, and when there is great difficulty in swallowing a cloth wet with spirit and water ay be applied over the mouth and nostrils. Cold water applied externally & internally has been recommended but is dangerous. It may be used however as a preventive. # Eupatorium etc. I have known some phys. generally successful [illegible] breaking up quinsy with cold water but as I predicted there was danger of the translation to the brain he lost one patient in this way “It may be used as a preventive” When the trails are much enlarged it is customary to bleed I would bleed it there was much fullness and strength of the pulse I have often bled and seen it done without the beast benefit still however without any injury as I could perceive “V. S. is important when there is danger of affection of the brain” Scarifying is generally practised. It is sometimes beneficial but often it increases the disease as is the case when a boil is scarifyed I do no t know that I can point out the circumstances which it is beneficial but if there is much irritation I think I would not scarify I have often had my own throat scarifyed without benefit Perhaps it is as often as once in 20 cases that the disease proceeds to suppuration. But if you puncture the swelling be careful to see where you introduce your lancet Case of [young] an opening was made which subsequently caused a troublesome sore the swelling burst of itself In various cases astringents was useful Lister’s [scoriae] (devils bit button snake root) it acts a little like seneka stimulating the fauces it operates considerably in a decoction It has been much used not of much consequence I have not much confidence in gargles The patient cannot gargle But you will give great relief by washing out the mouth with warm water or with mucilages or with a little old spirits and water which is very grateful to the patient Wash off the [illegible] which [illegible] Great advantage is derived from injecting with considerable force with a syringe & washing on the parts Spirits & water will be grateful & reviving 118 When there is redness and swelling but not extreme irritability, scarification is beneficial. If there is irritating soreness or inflammation scarifying will aggravate it After the inflammatory stage is past, blisters may be used I have not been successful in scarifying Bleeding may be necessary, if so it will be indicated by pain in the head and a full & tense pulse. When suppuration is about to take place poultice may be applied externally & vapor inhaled The latter remedy may be administered, very well in the following manner. Put a vessel of hot water in the bed, by the side of the patient & cover him with a sheet. # Touching the tonsils with nitrate of silver, is highly useful If the ear is affected, wet a piece of cotton with strong ammonia and apply it to the dear. it produces a pungent sensation and often gives relief The [liatris] scariosa is used in quinsy in the form of a decoction of the root. It is expectorant, diaphoretic & diuretic. It is called “devils bit” “After the inflammatory stage is established apply blisters” “If the irritability is extreme apply mucilages” “[illegible] & diaphoretics have been used in the early stages and are undoubtedly serviceable” # If you cannot well distinguish where suppuration has taken place, you had better not attempt to open the tonsils When the swelling is great poultices are very beneficial Dove’s [Dury] poultice Devils dung asafoetica Album graicum blown through a quill!! much used by my predecessors in this place Cathartics are proper early in the disease neutral salts if the fever if phlogistic Diet & regimen Give while the patient can drink, nitrous ether & water or a acidulated drink etc. Feed with arrow root etc. for the diet When the inability to swallow has continued sometimes the action is not enteric & the patient shd not be bled nor exhausted by cath. The disease is at this time principally local & from want of food etc. the pulse becomes feeble spirit and water injected into the throat will bring grateful and reviving [illegible] exhausted patient “Apply poultices keep the bowels open with enemata” “Inhale vapour of ether” Various gargles are recommended such as chlorine muriatic acid & water etc. but when there is much action they are apt to irritate Camphorated gargle vapour of camphor etc. There are a variety of these things which are mere palliatives The difficulty of swallowing is not caused so much by the swelling as by the soreness and pain for I have seen patients declare themselves much relieved and able to swallow when upon looking into the throat I could perceive no change in its appearance 119 “Scarification is recommended but I could never succeed with it. If the disease were pure inf. scarif. would be of service but it is an irritation infl. & scarific. increases the pain & infl.” In [illegible] case a free scarific. made the case worse in every respect” There is a stage when scarifying is beneficial when there is redness & swelling but not extreme irritability” “Leeches have been applied in the inflammatory stage externally and to the tonsils. It is difficult to make them take hold on the mucous membrane, but they would be more effectual there” “Suppuration does not take place in one tenth part of the cases. There is free secretion but no solution of continuity upon extermination” “When suppuration is likely to take place use poultices and inhalations of vapour poultices of bread and milk with stramonium are serviceable Gargle or syringe the mouth with spirits & water or camphor” “When the disease is seated farther down in the larynx it is essentially the same” “White dry pigeon’s dung in a poultice with bread and milk was used by Dr [Monson] He thought the phosphate of lime of service” I prescribed it in one case and they mistook for it devils dung (asafoetida) & it did wonders. I did not tell them of their mistake” [illegible] state of fever is a better classification than Good’s. Good separates the disease under different classes making one part are [illegible] disease another an aff. of the blood vessels “Scarlatina & angina are sometimes considered as separate diseases, but they seem to be only different forms of the same disease” 120 Scarlet Fever This disease has been called by various names, among medical writers, though the popular English appellation has been scarlet fever with little or no change. Canker rash however has been its common popular appellation in New England, until of late. Under the name scarlet fever I include both scarlatina mitis & S. maligna & likewise the paristhmitis maligna or ulcerated sore throat called also malignant sore throat & malignant quins. Other names that have been given are Scarlatina mitis & maligna cynanche maligna paristhmitis maligna scarlatina anginosa Enanthesis rosalia is defined by Good Rush a scarlet flush appearing about the second day on the face neck or fauces; spreading progressively over the body; and terminating about the seventh day; fever a typhus. This author divides rosalia into two varieties simples or mild scarlet fever which he considers as being slightly contagious & paristhmitica with an ulcerated throat & a rash not so regular as that of the other variety. This he calls highly contagious Under the name scarlet fever I included both the common mild scarlet fever with a rash & nothing more and the most malignant forms of ulcerated sore throat with the intermediate varieties considering them all as being but different degrees of the same disease This disease with its varieties a naturally associated with pneumonia quinsy influenza etc. Quinsy is an exception persons who have had it are more liable to another attack So too in tropical climates even have what is called a seasoning As a matter of fact this disease is theoretically considered contagious practically not so no precautions being taken the patient not being separated nor the friends and neighbors refraining from coming “The notion of contagion may sometimes be useful in keeping away idle visitors case in Guilford” 121 Scarlet fever often appears as a sporadic and sometimes as an epidemic disease. In general it affects children and women more than men. Dr. Rush’s opinion Some say that the disease never persons over 40 years of age. When epidemic however it attacks persons of all ages, though even then the majority of cases are among children and persons of delicate constitution. In general persons who have once had the scarlet fever are not attacked with it again, still this rule is liable to many exceptions for I have known repeated instances of a second appearance of the disease in the same person. This partial security from a second attack is met with in various epidemics & we may say in general that a person who has had any one of several different diseases the same general diathesis is less liable to have another Scarlet fever is said to be contagious especially in its severer forms The fact is disputed but this is the general opinion. Some fevers are perhaps contagion & among them some forms of this may be so. It certainly, however appears to follow the laws of epidemics and I am inclined to think that the facts which have led to the opinion that it is contagion are better explained by reference to those laws. It is said sometimes to go through the country like the influenza. Like other epidemics, those of scarlet fever exhibit appearances in different seasons, being sometimes milk and harmless & at others highly malignant & dangerous It has occasionally been as # And because blisters applied produced mortification It swept off whole families The fever considered a typhus It is not always so It is sometimes [sub-entonic] always however of a typhous grade 122 as the plague. About a century ago this disease prevailed in this state in its most malignant form, sweeping off whole families. It was called the black canker because the sloughs in the throat turned black & this name, though the influence of tradition, inspires terror in this town even to the present day Since that period the disease has probably been growing milder up to the present time. In 1794 however it was very severe in this town in Litchfield county & over the state more malignant than it has been since. Subsequently to that period adult males have been less affected. The last severe epidemic in this town was in 1803. Though sometimes attended with inflammatory symptom. Scarlet fever as a general rule, is of the typhoid or typhus grade & when malignant puts on the form of typhus gravior or gangrenous state of fever Symptoms. This disorder, when not malignant, nor irregular, commences with ordinary febrile symptoms general disturbance of the functions of the system, chills alternated with flashes of heat & pulse in most cases frequent and soft In severe attacks there is much nausea, sometimes vomiting, pain in the head back and limbs & great prostration The tongue of strength. In 1803 the disease frequently commenced with pain in the teeth or in the ear is the first symptoms In the progress of the disease there is more or less tendency in proportion to the violence of the disorder. In severe cases there is often great heat and dryness of the skin & perhaps the color mordax. In such cases also we frequently with an acrid discharge from the eyes & “When delirium is present it arises rather from inanition than repletion IT is accompanied with subsultus” Swelling of the tonsils is rather a favorable symptom Swelling and suppuration of the glands in the neck haemorrhage for the [illegible] & petechiae may occur 123 nose which excoriates the skin wherever it touches. Irritability of the stomach & vomiting are common & sometimes there is a troublesome diarrhoea. Petechiae may make their appearance. Case at [Hotchk??] town Haemorrhages sometimes take place; & in case of heat on the surface and what Armstrong calls congestive state of the system, a slight haemorrhage from the nose will be beneficial. Finally in the ordinary malignant forms of the disease the breath is very fetid. The epidemic of 1803 was characterised by great irritability of the stomach vomiting & diarrhoea pulse very low and feeble. In this epidemic after obviating the inverted action (of the stomach) stimulants were indicated. The throat is more or less affected from a slight redness to a deep slough. Sometimes there is a high degree of inflammation of the uvula & tonsils at others a relaxation indicating astringents both conditions accompanied with a high degree of tumefaction. A common appearance, in the commencement of the severe form of the disease is that of a white coat upon a part of the tonsils In the progress of scarlet fever, the affection of the throat may be more or less troublesome. It often terminates in ulceration & sometimes in gangrene In three or four days from the first appearance of febrile symptoms or rather on the second day of the fever the eruption appears in the form of a fine rash as described in the definition. In about as many days from its appearance about the seventh day of the disease it disappears Peculiar dulness of the eyes hollow sound of the voice patient appearing much like a night walker The first case of the kind which I saw I had no doubt about The friends had doubted whether he was sick enough to send for a phys. I declared at once that he probably would die. This was a case of pneumonia notha Most resembles measles Ordinarily distinguished readily sometimes with difficulty If scarlet fever is accompanied with a running of the discharges from nose with catarrhal symptoms, and is somewhat distinct in its eruption (hard under the touch under the skin) and such cases occur it cannot be distinguished from measles except by the general character of the epidemic I used to notice in the first commencement of my practice that on the first breaking out of the epidemic the older phys. used to wait and observe several cases before they decided upon the name 124 with branny scales & in ordinary cases the patient is then out of danger. The eruptions, however may vary much & even be altogether wanting the local morbid action being determined wholly to the throat. Ataxic cases will have no eruption. The worst cases of scarlet fever are those which transcend ordinary febrile action. In these the patient is scarcely sensible of being ill, appears dull and languid, his countenance indicates torpor of mind, he has little irritability of mind and is indifferent to surrounding object, his extremities are cold & his pulse small frequent and feeble & perhaps intermitting. Upon examining the throat ash coloured sloughs are found upon the tonsils and uvula. In these cases life is extinguished without any reaction of the system in the course of 24 or 48 hours, unless the tendency to death is obviated by the most powerful treatment. These ataxic cases resemble the ataxic cases of yellow fever pneumonia typhodes etc. which have sometimes been called walking cases The scarlet fever is liable to be confounded with measles, the disease which it most resembles. The marks of discrimination are these. In measles the eruption is less diffused is in pimples or circular dots more pointed & partly distinct & partly in clusters & the pimples produce a palpable roughness of the skin. In scarlet fever the eruption is diffused like erysipelas & consists of innumerable points or specks under the cuticle, intermixed with minute pupulae In some cases the eruption is in irregular patches & in others are uniform flush “Symptoms of pneumonia rarely attend scarlatina” This is one of a series of epidemics. It is usually followed or succeeded by measles & is followed by hooping cough For only it probably existed only as an epidemic now we meet with sporadic cases continually 125 while no roughness is felt, except in a slight degree upon the arm. The two diseases differ also in the time at which the eruption appears. In scarlet fever it shows itself upon the face and arms on the second day, but in measles it is not seen upon the arms till the fourth day. The scarlet fever is distinguished also by the absence of the catarrh, cough & determination to the lungs, suffusion of the eyes & the red and swollen state of the eyelids, which generally attend upon the measles. The latter disease also is generally accompanied by an inflammatory fever instead of the typhus which characterises the former. Still these two diseases of ten blend together so as to make the discrimination very difficult. It is barely possible that they are the same disease, though it may be objected to this view, that scarlet fever likewise is occasionally seen to blend with influenza # Epidemics of influenza are followed by [measles & scarlet] The prognosis in this disease will be obvious upon attending to the malignancy or the severity of the symptoms. In its severer forms it is always a dangerous disease & in its highest malignancy one of the most fatal while in its milder forms there is but little danger. # It is sometimes difficult to determine whether a particular case should be considered as one of scarlet fever, or of quinsy A case of scarlet fever in which there is no eruption & the tonsils are inflamed &swollen can be distinguished from one of quinsy only by attending to the state of the pulse, the prevailing epidemic etc. I have known it appear as an epidemic when it required nothing more than nursing One idea which I wish to impress particularly upon your mind, is that you must investigate the particular epidemic which you have to treat for no previous one will probably have been similar 126 The treatment of this disease must vary according to the diathesis. Epidemics of scarlet fever will differ widely in different seasons & different places & require very different treatment In a country where intermittent prevail the treatment will be different This has been some dispute about using the lancet in this disease. This will depend the degree of inflammatory diathesis. As a general rule emetics are indicated, but not always. Cathartics are generally improper but sometimes are required. In short indiscriminate treatment is as improper in this diseases as in any other. In this milder forms of scarlet fever, we may employ the usual treatment for typhoid fever, & administer those remedies which translate & keep up action and equalise excitement, as diaphoretics, the warm bath etc. For the mildest form it will be sufficient to give mild diaphoretics such as wine whey & elder flower tea, with perhaps a little antimony, acidulated drinks & gentle laxatives As the fever is generally of a typhoid or typhus grade, emetics are of especial importance in its treatment. They affect particularly the mucous membranes and may be repeated in the course of the disease, for the purpose of throwing off the accumulated mucus. The violence of the disease may often be completely broken by an emetic “In some epidemics when there is considerable action cath. of cal. are important especially in intermittent districts Rx cal. & jal. as for remittent bilious fever” “When there is tremor paleness, cold sweats, vomiting diarrhoea, cathartics might destroy the patient We must rouse the patient by counterirritants etc. and then we may go on with the treatment by emetics of ipecac etc. “Dr Rush bled but f.s. is very rarely indicated and in such cases as approach to A. tonsillaris” “Still it [illegible] all forms entonic atonic etc. “If malignant give bark & the min. acids. If the system does not respond give cantharides & capsicum oil of cinnamon cloves or cajeput” 127 at the commencement. All writers agree in recommending them. [Witherin] advises ipecac grs vi & tart. ant. gri for an adult followed by a strong decoction of senna Dr Rush recommends the turpenth mineral 2 to 6 grs with the view of strangling the disease in its birth. Sulphate of zinc is a good emetic & is preferable in the latter stage. It is local in its action & tonic in its effect. It operates speedily and produces less exhaustion. Vomiting by snake root has been practised In the irregular forms of scarlet fever, this practice is more questionable & if emetics are given they must be preceded by stimulants to rouse the powers of the system Cathartics are sometimes needed & calomel is to be preferred The judgment of the physician however must be exercised & the character of the epidemic studied, for great caution must be exercised that the system be not weakened by them & in extreme debility they should be preceded by stimulants. In some epidemics they will destroy the pat.” In some epidemics bleeding may be proper, but the apparent indications for it will generally be better answered by leeches about the throats and [temples] In malignant cases where the powers of life are very feeble no evacuations are to be used. External irritants are to be applied to rouse the system such as ginger mustard brandy a paste of mustard spts. turpentine & aqua ammoniae etc. Internal stimulants must be given Ammonia with bark opium etc.” “Tinct. canth 20 drops once in 2 hours till there is some effect.” “Serpentaria with ammonia acts as a tonic and diaphoretic” Where there is a prejudice against cold affusion with water alone spirits or [illegible] or camphor may be added 128 [illegible] to 4 [illegible] 3 or 4 such as capsicum Capsicum especially when the stomach is debilitated 4 to 5 grs [illegible] Cantharides in 20 drop doses. Ammonia camphor quinine, mineral acids etc. Carb. amm. & cantharides may be given to excite the system & be followed by bark and brandy to keep up the excitement. Diffusible stimulants also may be required, such as chloric or sulphuric ether 20 gtts to a teaspoonful of water for a child. In small children if there is difficulty in getting down medicines the bark may be given by injection, or the body covered with it, by means of a bark jacket. In severe cases, not of the most malignant form, the heat and dryness of the skin are often very great & calor mordax may exist. Cold applications to the skin, especially those of stimulating kind will then be beneficial. The cold bath cold affusion, or sponging with vinegar & water or spirits & water may be used according to circumstances. The cold bath or affusion of cold water may be superseded in case of prejudices on the part of the [illegible] or objections from other causes, may be superseded by sponging the body with vinegar & water If the case is attended with extreme debility and relaxation of the system or if any chills are present sponging must be used & [illegible] with caution. If the cold applications produce a chill or if the eruption comes out irregularly. I should advise the tepid bath to determine to the surface. In the advanced stages of the disease when debility & relaxation are great the vinegar & water should be made tepid & spirits may be added. The rules with respect to these applications are the same as in typhus. In the atonic form of “In children with disturbance of the stomach and pain in the bowels at the same time the eruption not coming out well use the tepid bath It obviates the tendency to convulsions and makes the disease regular In the most malignant forms it is inadmissible” “If there is irritability of the stomach give chloride [illegible] 4 grs 2-3 hours absorbents counterirritants” “In the latter stage of protracted cases emetics of sulphur zinc or copper are very useful” “Withering advises in the typhoid state, after evacuating the stomach & bowels to give senega freely This would be injurious in a malignant case” 129 scarlet fever, the cold bath or cold affusion must not be used IN 1803 I used sponging with vinegar and gave internal stimulants at the same time as min. ac. alc. brandy For children the tepid bath is invaluable in scarlitina particularly in the early stages of the disease and when the eruption is not fully out, or where the eruption is irregular. It is questionable however, how it would succeed in the most malignant form of the disease If there is great irritability of the stomach with vomiting, absorbents and counterirritants are to be used & in malignant cases capsicum, tinct. canth. & care to be given In cases of vomiting saffron & snakeroot If there is much diarrhoea we may give # white decoction with opium, injections of laudanum etc. astringents etc. In ordinary cases, when the eruption has been regular & ends with branny scales, about the seventh day the case is out of danger But when the disease is protracted sulphate of zinc or Moseleys tonic solution is to be given as a tonic. The latter article in a dose from a teaspoonful to a tablespoonful is an emetic in cases of great morbid action. Emetics of sulph. zinc & sulph. of copper have been recommended also of acetate of copper The latter article is also escharotic tonic & caustic. The chlorides chlorates are adapted to this stage of the disease [illegible] [chlorate of potassa] grii to vii “In those cases that require stimulants blisters may occasion gangrenes” “When there is tumefaction of the tonsils use blisters paediluvium & gargle with the mur. ac. especially the [oxymorestic] diluted with 6 parts water” 130 The treatment of the local affection of the throat is of two kinds, external & internal When there is much inflammation about the throat, with the uvula elongated, the tonsils enlarged an inflamed & the pulse full I apply epispastics externally. Blisters, mustard, oil of origanum ol. monard punct. etc. may be applied to the throat Gargles are injurious in bad cases & perhaps of little use in most. Still in ordinary forms of the disease from four to six ounces of any mild astringent acidulated perhaps with muriatic acid may be thrown in by a syringe. The marsh rosemary is considered better than any other astringent. The alum root (henchera amer.) is useful both as a gargle & given internally. For the latter purpose sweeten it & add a little brandy When there is not much tumefaction & considerable relaxation of the parts stimulating garbles are good, as capsicum & brandy astringents may be added. In gangrenous cases quinine is good if it can be got down. In the latter stages of the disease it may be useful to touch the ulcers in the throat with nit. silv. “Vinegar & lemon juice may be used as a gargle” “If the ulcers are thick and leathery apply nit. sil.” “I have seen the brain affected and much spasmodic action subderangement pain in the head and all the symptoms of hydrocephalus with a bloating of the whole cellular membrane pulse frequent & extremely quick and all the marks of irritative actions For 3 or 4 years I have used tinct. dose in 4-5 & sat. tinct. canth. in 10 3 or 4 times a day giving also the tonic solution and keeping the bowels open” “It produces eruptions on the skin, heat dryness & soreness of the fauces febrile action & if continued 8 or 10 days I think it would be useful. I would try it were the disease severe and epidemic, whether I thought it contagious or not” 131 The sequel of scarlet fever is dropsy. In children especially an anasarca and sometimes an universal dropsy comes on after the disease has subsided. The first two cases which I met with were in the severe epidemic of 1803. I treated them according to the direction of the books, with bark & brandy opium & lost my patients Considering this as an affection of the absorbent and nervous system I treated the subsequent cases which fell upon my hands with tinct. cantharides & tinct. digitalis The digitalis allayed the morbid action of the exhalents & absorbents & the cantharides acted as a diuretic. “Give of each 2 or 6 drops every 3 or 4 hours It [opens] [illegible] in these cases the effect of irritative action hence the propriety of digitalis Hanneman proposes to prevent the recurrence of scarlet fever by the administration of moderate quantities of atropia belladonna an article which produces an eruption upon the skin, similar to the rash of scarlet fever. The influence of belladonna, upon this hypothesis is similar to that of vaccination in preventing small pox. The termination of the chain of actions in health in some diseases & if we say nature cures the disease then we may say when the tendency is [inevitably] to death that nature commits suicide. The latter is true of this disease Yet if this chain of morbid actions is broken up by a powerful impression the constitution will take on its ordinary action Scarce any disease is more curable when taken in season yet it would not be proper for a physician to say he could cure all cases then pretending infallibility I shd doubt whether Good had ever seen the progress of a single case. He says nothing about the first stage. The tendency of the disease is to destroy the patient not by infl. or irritation but by suffocation from a foreign body in the trachea The stages run into one another, and yet a phys. watching the progress would naturally divide it into three stages Always curable in the first stage unless complicated with some other disease rarely in the second almost never in the last yet I have known cases cured in the last stage The peculiar sound of the cough is alarming (in the first stage) even to those who have never before heard it Dr [Hesark] I have been told divides the disease as I have done into 3 stages and directs to give 2 grs. tart. ant. combined with ipecac. I shd give for the effect not according to the quantity. I put out 3 or 4 gr and give till the effect is produced rarely over 10 grs 132 Croup This disease has been called in America by the popular name of hives which is probably a corruption of heaves called rattles The name given it by Good is empresmia bronchitis. The most common scientific appellation has been cynanche trachealis or angina trachealis The persons attacked by croup are I have never [illegible] 3 and [illegible] almost exclusively children from 3 months to 12 years old # in one instance I have known it attack a person 60 years of age When it occurs in adults it succeeds other diseases I have known 2 or 3 cups of [illegible] “Croup sometimes though less frequently than most diseases, blends with other diseases as catarrh” Some have considered the disease as contagious, but though a few facts appear to favour the supposition, they are not numerous enough to establish a general law. Croup usually occurs in the winter and spring, when it is brough on by exposure to a cold and damp atmosphere. Children upon the sea coast are more subject than in the interior of the country, because exposed to more variable weather and more frequent [thaws] & notwithstanding the greater warmth of the climate on the seacoast For when the air is filled with vapour, the caloric of the body is conducted off with more rapidity than in a dry atmosphere, even if the temperature of the latter is colder. # It is principally confined to persons under 5 years of age though it sometimes attacks persons of all ages, and It is not precisely entonic or atonic & hence might be called specific in peculiar It is said that in croup the exhalent arteries are affected & in catarrh this [illegible] vessels Whether the different vessels are affected or not there is certainly a different action “I have thought croup might destroy life by coating the entire surface of the lungs with a mucous or membranous coat thus preventing the decarbonization of the blood” “I have never seen croup without more or less spasm; & probably in fatal cases it is always a spasmodic contraction that closes the passage to the lungs which is only diminished by the membrane. I never saw a case on the other hand of what is called spasmodic croup which did not if neglected put on the membranous & inflammatory form” A similar [membranific] inflammation exists in the duodenum 133 Croup is a specific disease of a peculiar kind and is never malignant. It comes on with all the symptoms of pyrexia and consist in an inflammatory affection of the mucous membrane of the larynx and trachea, which causes a remarkable shrill sound in breathing & a ringing cough by which those who have seen the complaint cannot fail to recognise it. The proximate cause is a peculiar inflammatory action of the system, determined to the exhalent vessels arteries of the trachea and bronchial vessels, where there is produced an exudation of coagulable lymph similar to that which forms on the membranes of closed cavities from inflammation & entirely different from secretion of the mucous glands whether healthy or unhealthy. This coagulable lymph which is thus exuded, always forms a membrane which lines the larynx and trachea, if the disease proceeds to a fatal termination, and causes death by suffocation. This appearance is always found in the tracheae of those who have died of the disease. The membranific inflammation distinguishes croup in its nature, from catarrh which is in all its varieties, an affection of the mucous glands Most diseases attack in the night “Diseases are cowards, they mostly attack in the night” Rush. “The peculiar ringing sound of croup is made in [expiration] that of hooping cough is inspiration” # As is the case when respiration is impeded by any foreign body there is a great deal of irritation # when the nose discharges [illegible] [illegible] it bronchial vessels secrete mucus and a new action takes place the patient will be apt to recover # The patient was subject to asthma and the croup was neglected until the latter stages finally died + “I have known this to happen only once In this case the friends were not alarmed because the child had been subject to catarrhal affections & the symptoms received no attention till the last stage” # Frequently appears to be [illegible] in the very commencement of the disease 134 This disease sometimes come on like a catarrh and continues two or three days without any alarming symptoms, until suddenly, & often in the night the peculiar symptoms of croup appear. At other times the first symptom of the disease is a severe paroxysm of suffocation attended with the hoarse & shrill ringing noise made during expiration like air through a broken tube & the peculiar ringing cough. The cough in its progress is attended with more or less of spasmodic action. # It is always dry; and when it becomes loose or when mucus is expectorated the disease is broken up and there is no further danger # It rarely continues so long as five days and is sometimes fatal in twenty four hours. Sometimes, though rarely the membrane of coagulated lymph is coughed up. I have met with but one case + In this the membrane was thrown up three times, at each subsequent time forming lower down than before # No disease resembles croup so much as suffocating catarrh yet there are obvious marks of discrimination The latter disease as I have seen it is not attended with much cough and the difficulty of respiration is not in paroxysms but constant & commence with the disease. The pulse is often quickened and when the system is prostrated may be low. # In suffocating catarrh the powers of life are to be raised by external irritants & excitement equalized by the inhalation of the vapor of [illegible] of warm water etc. “Mustard” “If pulse tense bleed” From the earliest of my practice I have been in the habit of dividing it into 3 stages [illegible] that they are perfectly distinct, but [illegible] person would naturally take this view Quiet between the [per.] apparently not much affected during the paroxysms Between the paroxysms pulse natural & eyes bright. You will know this disease in this stage only during the par. Parents in this place know the disease in this stage and send forth phys. In this first stage, the disease must be broken up by a powerful impression upon the system This may be done many ways Some are partial to a [illegible] & some to another “That which is best administered is best” A local effect upon the stomach will not answer I have relied more upon tart. ant. than any other & found it answer all reasonable expectations. I have preferred it to any other I have occasionally used other [illegible] I have found seneka better as an auxiliary than as a commanding [remedy] 135 Croup may be divided into three stages each of them requiring different treatment. 1st The forming stage 2nd The inflammatory stage & 3d The last or suffocating stage 1st In the forming stage, the cough is severe & hoarse & occurs in paroxysms of from five minutes to have an hour in interval. “There is little or no fever” The pulse is regular and small, & sometimes trembling. The patient is often chilly. In this stage the disease may with certainty be cured “I have not lost a patient & have not saved one in [illegible] when not called till the second paroxysm had commenced” In the treatment of this stage we must depend upon emetics. Large doses must be given moderate ones do no good. A dose should be administered sufficiently powerful to affect the whole system and call into action every muscle. We must be regulated not by the quantity but the effect for we must calculate to overcome the diseased action completely by the operator of our remedy. I have given three grains of tartar emetic to a child three months old, & kept up the action by the large doses of seneka repeated every half hour for six or eight hours Tartrate of antimony is the best emetic to commence with and may be given in a dose of from 3 to six grains of strong tart em. After its operation a constant nausea must be kept up by seneka or some similar article, for some time in order to prevent a return of the disease. The seneka excites a new action in the system. It may be given in decoction. Take zfs or zi of bruised seneka to half a pint of water, & boil away a quarter. Give a table spoonful for a It has so happened that with us the [serpentaria] has not answered so well as tart ant. It acts on the fauces perhaps more [illegible] than tart. ant. but does not affect the system act upon the skin & determines to the surface so well as tart. ant. We have not used it however except in the latter stages & perhaps have not given it a thorough trial Sanguinaria vide p. 212 has been used 50 perhaps a hundred years. Three generations of physicians in one locality have used it and relied on it in croup with as much success as upon other articles These mode of using it was in strong decoction without weight & give a table spoonful until the desired effect is produced till vomiting is excited or the disease is broken up There are however forms of the disease where it fails even in [illegible] “Much has been said of the good effects of calomel Give in large doses 20 – 30 [illegible] acting as an emetic it is serviceable but when catharsis is produced, the emetics would fall in with the catharsis. I never could in such a case make the strong impression on the system what I [illegible]” 136 does once in half an hour or as much as the stomach will bear. Seneka has been relied upon by some as a specific in croup, but it is inefficacious when inflammation is present, being a stimulant, and it is too slow in its operation for the first remedy. After giving it as the first article, other emetics seem to lose their influence; acting as cathartics; but after the violence of the disease has been broken up by other emetics, you may avail yourself of the nauseating & deobstruent effects of the seneka & effect a cure. Dr Rush preferred the turpeth mineral 2 to 6 grs as the first emetic. The physicians in Wallingford for 5 years make a strong decoction of sanguinaria, and give it until emesis or a cure is effected. This article may be used instead of seneka in the way above directed In connexion with these means the warm bath and fomentations may be used as adjuvants. Much has been said of the good effects of calomel in this disease You cannot rely upon calomel for the cure of the disease It is too slow in its operation. Never give calomel until you have broken the violence of the disease After emetics have operated and you have availed your self of the operation of seneca & sanguinaria and the disease still exists, give from 5 to 10 grs of calomel By this producing an orgasm in the system more powerful than the disease & continuing it until the latter be overcome, croup may be cured with more certainty than most other diseases. All diseases should be attended I know that there are some very respectable physicians who rely upon calomel For this purpose they give very large doses and produce [illegible] & [illegible] I should prefer it as an auxiliar. I have often used it but after the emetic or with the emetic or before the emetic A variety of other men [illegible] India tobacco which though not allied in botany are so in their operations The common tobacco is generally applied eternally to the pit of the stomach. Lobelia acrid & emetic loses some of its virtues by drying In its recent state 1 gr will often excite full vom. Indeed I have known vom. prod. by merely chewing the capsules & [illegible] without swallowing by the impression upon the mouth Dose of tinct. 20 drops to a t. sp. according to age Other acrid narcotics as veratrum & colchicum may be used In this forming stage bleeding is not indicative by the pulse, nor by state of the system and you will obstruct your efforts to excite a powerful effort of the system if you bleed 2nd stage In this acrid emetics are injurious seneka is too stimulating Sanguinaria had I have seen all the symptoms aggravated by bloodroot in [illegible] the high entonic stage # “If the disease is complicated with a similar affection of the stomach & duodenum give calomel & other cathartics” 137 to in the beginning & it is owing to the imperfection of or our art that every disease is not broken up in its first stages. When however croup supervenes upon other diseases, it is more dangerous. “Those who practice in the country rarely see the disease in the forming stage. I had one winter 20 cases of croup all in town recovered most of the in the country died” 2nd Country practitioners however seldom see this first stage which I have just been treating of when the tongue is not discoloured, the fauces have a natural appearance the pulse is unaffected respiration natural & ordinarily no inflammation about the tonsils. On the contrary they too generally arrive when the disease is in the second or inflammatory stage the disease has effected in which the bloodvessels the skin is hot and dry, the face flushed, the pulse tense & sometimes full the tongue furred, respiration between the paroxysms difficult tongue furred, respiration between the paroxysms difficult and the cough so severe as to threaten immediate death vide p. 213. In this stage we should immediately bleed from freely from a large orifice the arm or jugular vein freely, even until syncope is produced put the patient in the warm bath & let him also inhale the steam of warm water, and give calomel and other cathartics. # Never give emetics in this stage until after depletion by V.S. when we may give 4 grs. of tart. ant. in a table spoonful of warm water & apply epispastics to the throat” in the commencement apply a blister” I dread to be called in this stage of the disease, for it is the almost always fatal venesection sometimes succeeds but very seldom. I would not apply leeches cupping would be better & perhaps friction might be serviceable. Digitalis has been recommended, but In this stage inhale the vapour cover the child & nurse in a chair with a blanket In this stage cal. & cath. may be given In the first stages I have conserved it very unfortunate to find my patient under the operation of a cathartic It feels as if my hands were tied The excitement is of a different kind from what is wanted And emetics are apt to produce hyper cathartics Where the dis tends to the [illegible] the [illegible] a specific. This is known by the cough being less hoarse, by fever, by constipation fever more intestinal membrane will pass off from the duodenum I was formerly disposed to cure this form of the disease [illegible] & described it as such In the second stage epispastics over the whole chest also diaphoretics and tepid bath When the cough is milder and beginning to be loos after being principally broken up in the first stage give cal. in 2 or 3 gr doses once in 2 or 3 hours In the 2nd stage remedies have been given to obviate the fever & digitalis has been used with good effect It was used as a depressing agent It operates by its narcotic power however. here refrigerants are of little efficacy In what may be seen to be the last 138 I have not used it. It is at best but a doubtful remedy in inflammatory effections though calculate to remove more irritations. Sanguinaria diminished arterial action like digitalis and operates powerfully as an emetic. I have not succeeded with it in the last stages of croup & have not used it in the first. [?ronchotomy] has been proposed, but does not promise much benefit, as the disease is seated below the place for operating. “Dr Smith did not recommend it” After depletion and especially after the disease assumes a bilious form you may give powerful cathartics The pt. begins to thrown his head back death may happen any moment 3d IN the last or suffocating stage* you may give emetics of turpeth mineral sulphate of zinc or even corrosive sublimate to throw off the membrane. Something may depend upon changing the emetics & sulphate of zinc may be tried. The cold bath is said to have been successful in this stage, but the fact is not well authenticated. I have used calomel and the warm bath with advantage. Child of Mr Culver [last] in chronic stage “I regret that I have not tried affusion of cold water in the last stage. It is said to cause the membrane to be thrown off & to procure relief even in the very article of death” vide p. 182 *”In the last stage respiration is constantly laborious head thrown back pulse often irregular & intermittent sometimes strong” Chronic form “Sometimes though rarely the disease is only partially subdued I [illegible] on in a chronic form. Calomel vapour best tepid bath are the appropriate remedies” 139 Angina Laryngea Empresma Laryngitis of Good, q.v. for a definition & an account of the disease In this disease the symptoms differ somewhat from those of croup, though the cough is similar The disease is seated in the larynx glottis and fauces & the characteristic symptoms is swelling of the tonsils. The cough is spasmodic and is excited by taking food with drink in this respect also indistinguished from croup. The disease is more violent and rapid than croup, as the inflammation being seated in the narrow part about the glottis produce suffocation sooner. The respiration is more difficult than it croup particularly between the paroxysms This disease more commonly affect adults The first case that I saw was that of an old man in whom the disease was brought on by exposure to cold after a pneumonia From a relation of his symptoms I prescribed seneca which only exasperated the disease, so that when I saw the patient he was unable to speak or swallow. A small red spot appeared on the tonsils. venesection, epispastics, pediluvium, inhalation of vapor etc. were resorted to with no abatement of the symptoms. Venesection was performed a second time & as soon as the patient was able to swallow, 4 grs. of tartar emetic were administered. Some nausea and vomiting with considerable catharsis followed. The vesication “Angina laryngea is mor apt than croup to recur several nights in succession” “The slough were thick and leathery. Sloughing even under blisters. In one instance blisters did not heal in 4 mo. Lunar caustic applied to the tonsils & uvula & inflamed parts proved serviceable # “In one case of A. laryngea I gave sanguinaria It was too acrid and increased the cough etc. It might do good if we could avoid the local effect of its acrimony” 140 was extensively returned & the patient recovered. Much the same treatment is required as in croup but it should be more prompt and with earlier venesection. For the inflammatory stage comes on earlier and the disease runs a more rapid course Last year this diseases differed in its appearance from the former years It has often followed certain affections of the tonsils called black canker. The tonsils are inflamed in black canker and sometime covered with a leathery crust. This comes off and leaves an ulcer. If the inflammation extends to the larynx, symptoms of croup supervene Case of black canker. Two called in the last stage gave blood root with disadvantage # Still at this late period calomel and other cathartics in large doses produced free evacuations and the child recovered Cathartics appear to do better than emetics. In one case after giving cathartics I used the vapour bath and applied a large epispastic over the whole sternum. Though at so late a period the disease abated. A large slough however was produced by the blister which required three months to heal. The morbid action on the skin being similar to that of the tonsils Vie p. 187 Sometimes comes on with a sudden paroxysm of suffocation sometimes gradually “Distinguished in its commencement from croup by the quantity of mucus in the bronchial vessels” “in the case which I have attended, not much febrile action attended the disease” Proximate cause a morbid action of the lining membrane of the lungs accompanied with a viscid secretion of [mucus] By vomiting the disease may be relieved & apparently cured but may appear again in the course of an hour The quantity of mucus is greater than in any other catarrhal affection” 141 Catarrhal epidemic resembling croup Peculiar catarrhal affection resembling croup suffocating catarrh This disease is characterised by a severe hoarse cough, much resembling that of croup. The disease is distinguished in its commencement from croup by the excessive quantity of mucus in the bronchial vessels which causes the suffocation The disease resembles croup likewise in the mode of its attack which is sometimes sudden with symptoms of suffocation, and at other times gradual with paroxysms of coughing and intervals of perfect ease The turns of coughing are so violent in this disease as to produce a livid colour of the face. The extremities evident determination to the head are cold and the head is hot from the quantity of blood thrown into the vessel of the head by coughing. The evacuation from the bowels are healthy and among children with no disease which I am acquainted affect the bowels so little ass this. The proximate cause of the disease is a morbid secretion of mucus on the lining membrane of the lungs & trachaea with obstructed perspiration. The quantity of mucus thrown out by this membrane in this disease is astonishing After the disease is fully formed, great quantities of viscid mucus may be brought away by vomiting, to the great relief of the patient for a short time, and yet within an hour the patient will appear to be suffocating from the the quantity again collected in the bronchial vessels In the commencement of this disease, the indication is to break it up at once by a powerful emetic, of tart. ant. unless the system The principal indication is to break up the disease by a powerful action on the skin on the stomach the duodenum and the fauces It is best affected by tart. ant. which is more difficult in its action than [ipecac] though is very delicate constitutions ipecac may be practicable # prevent accumulation of [mucus] The bowels shd be evacuated not for the purpose of curing the disease but for the prevention of an accumulation of feces which would be irritating In all diseases of the lungs examine the state of the skin and particularly that of the lower extremities for perspiration upon the upper extremities [only] may be a part of the disease I have known the lives of several patients saved by the use of the vapour bath I formerly [illegible] and used [illegible] for transmitting vapour by transmitting air through boiling water It was old practice to apply cat-skins fowls split open (to the feet) etc. with the intention of communicating vitality 142 is too much weakened to bear this treatment. This is a general principle viz, if possible to break a disease in its commencement by means of a strong orgasm. Often the emetic is to be repeated, and it may ever be necessary to give four or five emetics 1 gr [illegible] tart. emet. each in the course of a day. After the disease is somewhat broken up, and epispastic applied upon the breast will assist much in allaying its violence # If the disease still continues or if when first called we find it fully formed and powerful emetics inadmissible the primary indication will be to open the pores of the skin and keep up a gentle perspiration, by small doses of antimonial wine to which may be added in all quantities of camphor by elix. [illegible] & in some cases tinct opii by fomentations and especially by the warm bath and the inhalation of vapour. To affect the latter object the child may be placed in the warm bath & a blanket thrown both over it and the nurse, so as to keep the child in an atmosphere of vapour. Long continued perspiration invariably relieves the symptoms. I have known an instance in which the skin of a sheep warm from the animals body was wrapped round the naked body of the child with beneficial effect. In small children when the stomach ceases to be excited by emetics the throat should be irritated by a feather or the finger, when we wish to produce vomiting For we must never rest satisfied with merely endeavoring to palliate the symptoms. In small children also the mucus should be wiped out of the mouth by the finger or a cloth This disease prevails most in the winter and spring months & does not occur every year. The first patient that I treated for the disease suffered from it a year. I gave mercurials & finally the silver pill (nit sil) 143 I was puzzled with the first cases of this disease which I met with. Some of them continued for weeks and months I was obliged to use perspiration, by warm bath to vapour bath emetics etc. I determined to break up the next cases in the commencement with tartar emetic repeated until full vomiting was produced walking my patients. This plan was more successful A s a general rule break up all diseases if you can “The complaint is epidemic or rather endemic. It has been mistaken for croup, but it differs As croup formerly occurred no mucus was raised in the earlier stages, and when there was an excretion of mucus we considered the disease cured But of late years the two complaints are somewhat blended. Mucus is thrown off sometimes without permanent relief” “There is often in this disease a disturbance of the brain and nervous system resembling epilepsy or chorea produced by the cough” A distinction was formerly made by some writers and some practitioners, between hooping cough and [chin] cough the latter being a spasmodic cough without the hoop. Such a distinction will not hold good there is no difference “Linneas and Rosenstein attributed it to an insect others to malaria” There had been a very severe winter & no one had left the island for months 144 Hooping Cough Pertussis Called also chincough This is a disease which generally attacks children yet occasionally, adults are the subjects. I have known persons of 60 years of age affected with it. As a general rule also it does not affect persons a second time. I have known about 20 or 30 exceptions & among them was the late president Dwight at 60 years Hooping cough generally appears as an epidemic. With respect to its origin there is considerable difficulty in making up an opinion. It is said to be contagious to arise from a specific contagion which affects a person but once. Dr [Dewers], however, says “We confess that we are inclined to believe that it depends upon causes of a more general and pervading influence that contagion.” Dr Cullen asserts that he has said a disease which though evidently arising from chincough contagion never put on any other form than that of common catarrh. In the tenth volume of the medical commentaries DR Willey gives an account of the breaking out of the disease on Block Island under such circumstances that it would seem that it could not have originated from contagion. When the disease prevails many become effected where every precaution is taken” When the disease has been extensively prevalent I have not been particular about keeping patients apart, perhaps however it is best for prudence’ sake to consider the disease as contagious and to treat it as such. One fact I have noticed that in particular seasons may have the disease who have had it before.” Some suppose that it is contagious only in the first stage others in the second “Some think it caused by malaria or animalcular” “The stricture may be overcome by not attempting to inspire, but to expire till the lungs are emptied the pat. can then inspire without difficulty I have known persons subject to this kind of hooping without cough Adults are sometimes attacked in the night with paroxysms of suffocation they start from bed when the recover their breath there is hooping but no cough, at least at first The more they struggle to catch breath the greater the difficulty there seems to be a spasm of the glottis Let them make no effort to inspire but expire the little air remaining in the lungs & they will bye relieved at once. The disease is liable to recur bathe the feet at night give paregoric wine whey diluents The disease is not described 145 Some suppose this disease a peculiar inflammation of the mucous membrane of the trachea and lungs, others that it arises in the bowels This disease often commences with the symptoms of ordinary catarrh & continues without alteration for some days. Sometimes the peculiar mark which gives this cough the appellation of hooping & distinguishes this disease from every other does not appear until the 3d or 4th week It is impossible however to distinguish the disease until this peculiar hooping makes its appearance. When the disease is prevalent it will be safe to treat every severe case of catarrh among children as one of this disease The phenomena peculiar to this disease may be the described. Several frequent expirations are made in succession by spasmodic coughing, and a full inspiration is then necessary to restore air to the lungs. The air as it passes rapidly into the lungs produces a loud sound called whooping The sound however is made more by the structure of the passage than by the rapidity with which the air is drawn into the lungs I have known persons subject to this kind of whooping, without having a cough caused by a spasm of the muscles of the trachea larynx? to which adults are sometimes subject. (Goods laryngismus?) A similar sound is also made in croup, when the air is expired after the passage becomes constricted The patient is aware of the coming on of a paroxysm of coughing by an unpleasant sensation in the throat, & The cough is violent in proportion to the shortness of the paroxysm 146 it is common for children support themselves during its continuance by changing to a chair or other support near them. During the paroxysm the blood is returned with such violence to the head as to produce a livid colour of the face & often in bleeding at the nose. Very violent paroxysm sometimes in young children terminate in convulsions or death The paroxysms continue until a quantity of mucus is thrown up from the lungs or the contents of the stomach are evacuated by vomiting They are short in proportion to the facility with which the mucus is brought up or rather in proportion to the rapidity with which it is secreted It is the secretion of mucus, not its removal which gives relief to the irritation of the lungs Many suppose that this mucus which is generally in considerable quantity is the cause of the paroxysm of coughing instead of the effect of it. The peculiar irritation of membrane in a paroxysm of coughing produces a secretion of [illegible], and when a sufficient quantity has been secreted it is coughed up like the secretion of tears from an irritated eye and the paroxysm is relieved “The mucus sheaths the part & the ceases” The disease continues from one to six months It is often kept up by habit. The cough is usually more violent by night than by day. Violent cases are often attended with considerable fever and in the worst cases respiration is laborious between the fits of coughing. The disease may terminate by apoplexy or suffocation or by ulceration of the lungs and hectic & sometimes by permanent visceral obstruction “or apoplexy or suffocation” Whooping cough is not dangerous to adults and I have never known a child over two years of age die with it. It is most dangerous to infants and the younger the It is usually dangerous to children within the mouth It is apt to wear out very young children especially if they are of a scrofulous tendency It is frequently accompanied with a morbid sensibility and irritability of mind and hence in the latter stages a change of air and of place is salutary as in cholera infantum The same despondency of mind takes place as in chol. inf. q.v. The disease is a fever spending itself upon the lungs and trachea, and affecting also the glandular system Some phys. think this dis. like common catarrh, is always inflammatory in its commencement, and requires antiphlogistic treatment. But we know that pneumonia may be highly typhoid & require treatment opposite to [enteric] pneumonia. If infl. of the lungs exists the antiphlogistic treatment shd be adopted in its fullest extent I have seen antimony as efficacious in this dis as in pneumonia. In general perhaps mild antiphlogistic diet & treatment will be proper. In some cases I have thought the veins lost their power, and in such cases the blood [illegible] has been prescribed & with advantage It is a catarrhal fever at first and to be treated as such 147 child the greater danger in children under the age two years The anger, to be apprehended from the disease will also depend upon the debility of the child when attacked. The cough may be violent and attended with frequent vomiting yet of the patient’s appetite be good there will not be much danger to be apprehended. A moderate hemorrhage from the nose is often salutary Treatment. If the disease is mild and the constitution good little need be done with the way of treatment. But if inflammatory symptoms supervene with a tendency to pneumonia the antiphlogistic treatment must be adopted. Bleeding will often be advisable. A small quantity of blood taken from the arm proves serviceable. In general greater effects may be expected from the application of a few leeches to the breast or neck than from bleeding at the arm but when decided symptoms of pneumonia appear, & the blood seems to be transmitted with difficulty through the lungs. I would recommend venesection. In this case also the bloodroot will be the best article for internal administration In most cases the disease comes on like a catarrh, and should be treated as such, with mild antiphlogistic regiment [illegible] important part of the antiphlogistic treatment of this disease is the keeping the bowels open. Costiveness frequently attends the disease & should be carefully avoided. In general it is better to obviate this symptom by diet as far as it can be done Begin with antimony in small doses 1l or 2 drops ant wine & in [illegible] For very delicate children however it may be better to give ipecac Almost all the writers recommend vomiting [Best] 148 rather than by medicine. The best cathartics for the indication are those which excite the secretions of the stomach and liver. Sometimes the disease has a tendency to produce congestion of the liver and obstruction of the mesenteric glands and in that case also mild mercurials should be given and their use continued as long as any symptoms of congestion exist. All the medical writers on this disease recommended vomiting in the first stage Tart. ant. is in ordinary cases the best emetic. Sometimes for a child from two to six months old two drops of antimonial wine will be an emetic dose while for another of the same age 20 or 3o drops may be required. In affections of the lungs children will bear antimony better than in those of the stomach and duodenum. In some constitutions antimonial emetics produce (in this disease) a sort of spasmodic stricture other emetics also may produce this effect a symptom which must be relieved by diluents and opium In general antimony in small doses may be given to children of any age, either by itself or combined with a small quantity of paregoric or any other mild preparations of opium. Given in this way it removes febrile action and congestion of the lungs, and determines to the surface When the disease has proceeded with You may see the fontanelles swell in such cases. I recollect a child in the whooping cough going into the country I told the parents not to suffer the child to be vomited. A physician in the country said the child must be vomited of course all the books directed it in whooping cough He vomited the child. It went into convulsions and died # Here insert the recipe for hire syrup or compd sys. of squills p. 150 I have known the lives of some patients saved by this antimony internally had lost its power produced no effect 149 violence for some time and there is much determination of blood to the head, threatening convulsions or apoplexy from distention of the blood vessels, or when the patient has become debilitated vomiting by emetics should not be practises or but cautiously. When the system and particularly the stomach has become debilitated. Ipecac is preferable to antimony, given in emetic doses, or in small quantities as an alterative diaphoretic and antispasmodic. And in the latter stages likewise on account of the debility, sulph. tinc. is a good emetic using 5 or 6 grs. with as much of ipecac If there is not much febrile heat, and there is much viscid mucus in the stomach and lungs, and emetic of squills is often serviceable # particularly I [illegible] phlegmatic temperaments syrup of squills vinegar of [illegible] In this disease if there is danger of convulsions from vomiting, blood root and similar articles should be given. The hive syrup or compd tinct. of squills may be used In children under three 6 months, whooping cough may be much relieved (respiration being promoted) by vesication on the breast. A blistering plaster may be applied but I have more generally used the following. Rx common or mild tinct. canth zi targ. ant zi Dissolve the ant. in the tinct. & apply a linen cloth with the mixture till [illegible] or partial vesication is produce & then dress with simple cerate In this way we have the vesicating & irritating qualities combined. This external use of tart. em. was recommended 20 years ago, in the Lon. med. & ph. Journ. This disease may be cured in its first stage but it ordinarily runs a regular course & the treatment is generally palliative brown mixture You will perceive that this is a strong decoction of seneka and squills, with a large proportion of tart ant. shd be given cautiously 4 to 30 drops Narcotics have been strongly recommended e.g. atropa belladonna & hydrogen of the former for 2 gr of the leaves in powder Alibert recommends the fresh bruised root 150 A popular remedy in whooping cough in Godfrey’s cordial, made of molasses and water with a little laudanum and oil of [illegible] “Hive syrup” (or compd syr [illegible]) is made as follows Rx bruised seneka root & squills zz z8 water lb 8 boil and evaporate one half strain and add honey 4 pts boil to lb 6 Add tart. ant. gr.i to every ounce Give for an emetic 8 or 10 20 drops to a child 4 mo. old & repeat the dose every 15 or 20 minutes until vomiting is produced The “brown mixture” is as follows elix. pareg. zi; ant. wine zfs; ext. glyc ziii pul. gum ar. zii wat. zvi trit. & boil dose from ½ teaspoonful to tablespoonful This has been very extensively used This disease has been prescribed for more empirically than most others; a fact which proves the difficulty of curing it It is a popular notion that it must “run its course” & under the influence of this many parents object to its being prescribed for. Undoubtedly this like every other disease must “run its course,” if it is not cured; but this is no reason why the cure should not be attempted. Ammoniae asafoetida (especially if the cough is kept up from habit) 1st antispasmodics 2nd tonics # An emetic is occasionally administered with advantage “I have prepared this from seneca oil also from gun copal” 151 2nd In the second or chronic stage tonics & antispasmodics are indicated. Sulph. of copper or of zinc tinct canth. cinchona, arsenical solution etc. may be required to rouse and support the system & as antispasmodic tinct. asafoet. petroleum Artificial musk etc. and also the narcotics, as hyoscyamus, conium, stramonium, belladona arnica, opium etc. When the cough is kept up by habit, # asafoet. is often administered to children with advantage. It may be given in tinct. or decoct. & if it cannot be given by the mouth it may be thrown up in an enema, using 10, 20, or 30 drops of the tinct. It is a valuable [illegible] the taste is less unpleasant than the [illegible] Artificial musk or oxygenated oil of amber was first introduced by Prof Hufeland of Jena as a specific for whooping cough and has since been found very useful in other spasmodic diseases vid. Lon. M of ph. J. vol. 1: p.181 van Swieten’s comm. etc. Rx nit. ac ziiifs cl. succini zi. And the acid gradually, ina temperature of 100 [degrees] or in the sun. Prof. Hufeland triturated x or xii grs. in a mortar with a few almonds & diluted with z 5 or 6 of water & gave a teaspoonful every 2 hours to a child a year old. This preparation was very celebrated and very effectual, for a time, but afterwards fail was thought to be ill prepared. The truth was the diathesis had changed. Probably it will be as affectual at [illegible] time I have given the above article in tinct. Rx zii of the oxyg. [illegible] [illegible] lbfs alcohol dose 10 to 12 20 gtts It is much more soluble in ether. I frequently dissolve zi of oxygenated amb. in zi of ether dose 1 to 2 drops on sugar 152 It may be prepared indeed of any strength, to suit the convenience of the physician. Probably gum copal oxygenated would answer the same purpose as amber as there is every reason to suppose that the two are essentially the same amber being gum copal mineralised Case of a vein of olibanum or Frankincense found in S. America. Opium is not indicated in this disease except when it is qualified and its action determined to the skin by antimony ipecac or camphor. Hyoscyamus is better than opium for in the cough it produces no constipation and the tincture is very pleasant. I have not however used it in this disease. Conium has been recommended by writers of the first respectability, but later authors do not speak of it with much confidence. It deserves a trial when other things fail. Alibert recommends atropa belladonna 1/6 gr. of the root or leaves powdered & given in milk I have used I have more confidence however stramonium in the [illegible] & think it preferable most of the narcotics to any other narcotic It is peculiarly calculated to remove spasmodic action depending upon irritability of the system or kept up by habit From the relief obtained by its use in asthma I was led to employ it in this disease and from those cases in which I have tried it I am of opinion that it is a very valuable remedy in it The ripe seeds of the stramonium are best the full dose of these for adults is gr. ii for a child 1/10 gr. or more according to the age Mercurials occasionally blue pill rhub & ipecac enough to keep up a gentle excitement in the bowels Not unpleasant to the taste An old [illegible] Chalmers ([illegible] of silver) recommends sulph. cop. & tinct canth in wh. cough # [ago] more used than any other Lately the ox. bis. has taken its place dose the same used for irritating cough & irrit. of stomach 153 Carb. potash is a good antispasmodic used externally and internally. It is not only antacid & antispasmodic but it appears to me to produce a peculiar excitement upon the stomach and aesophagus, which makes the more susceptible to the impression of other articles. Pearlash zfs & water z8 with cochineal enough to colour the solution has been considered relied on by some physicians a specific. The cochineal merely colours the solution. is an article from which I never could perceive any medicinal effects when used alone. I have tried the experiment & could perceive no medicinal effect from it Tonics. I have given the sulphate of zinc more than any other tonic in this disease, and have experienced the greatest benefit. Sulph. tinc given by itself, sometimes produces spasmodic action, the effect I attribute to its being used in substance & hence I always give it in the form of Moseley’s tonic solution. This preparation is both conic and antispasmodic is easily taken and retained on the stomach of very small children Sulph. copper possesses properties similar to those of sulphate of zinc. It is administered in the low stage of whooping cough. In this place the preparation of it called compd tinct vitr has been used according to the recipe in the 10th vol. Duncan’s Commentaries in doses of 3 to 30 drops according to the age of the patient The oxide (or flowers) of zinc & also bismuth formerly much used in spasmodic cough 30 grs have been occasionally used 1 to 3 grs 1 to 10 to an adult The Peruvian bark is a good remedy in the last stages. The only objection to it lies on the difficulty It sometimes happens that the physician is not called in until the latter stages. As one resort we may have recourse to irritate along the spine It is an opinion very extensively prevalent to that it is of no consequence what kind of food a child takes when he has the whooping cough But great attention shd be given Removal from sea side to country and [illegible] country to sea side either is beneficial 154 of administering to small children, a quantity sufficient to produce any considerable effect. This difficulty may now more be overcome by using sulph. quinine ¼ gr to 1 gr Dr Chalmers of South Carolina recommends a combustion of bark, sulphate of copper and cantharides Tinct. cantharides has been long since recommended for whooping cough. It is useful when the system requires an inflammatory diathesis to be produced. Its action on the stomach is probably similar to that which it has in cases of gleet and leucorrhoea the stomach being in a relaxed state & requiring to be excited to a healthy inflammatory action Irritants, as oil of capsicum canth. [illegible] or ol. orig. or vol. lin. rubbed along the spine have been used in the latter stages. They should be tried when you have reason to suspect that the spinal marrow or the nerves proceeding from it are affected. Attention should be paid to the diet of children in the whooping cough avoiding potatoes, oily foods etc. Change of scene & change of air especially by riding should be resorted to in bad cases, to tranquillise the patient & furnish mental excitement. Sometimes the little sufferers will be excessively irritable constantly worrying and teasing until this is done requesting first one thing & the other to be done. It is the worst of such cases, medicine does little good, even the irritation produced by administering it may counteract its beneficial effects. violent palpitation throbbing of the heart a soft flowing pulse and a jarring feel of the pulse under the finger ([illegible]) (The French call an enlarged heart hypertrophy I object to the [name]) For this I have given nit. sil. 1 or 2? gr. (in the chronic stage of [illegible]) Digitalis & also [languinaria] (tinct. 2 or 3 gtts.) This article is dangerous for children because it accumulates in the system Lead has been recommended I have been doubtful with respect to its propriety in affection of the lungs etc. # Pneumonia typhoides 1815 the system seeming to lose the power of [illegible] the blood and the bloodroot was given to promote venous absorption The digitalis might probably be given in such cases but is not as well adapted. I used the blood root and found as much benefit as could or [expected] from any article 155 If the patient having the whooping cough happen to be teething the treatment recommended for dentition should be employed The patients are very liable to have an inflammation of the lungs from taking cold in any stage of the disease & in such cases the remedies for pneumonia should be administered, such as antimony bleeding epispastics, bath etc. The disease I think sometimes determines to the head & produce a relaxation of the sinuses & [illegible] likewise produces a relaxation of the ventricles of the heart the immediate cause being the violence of the cough In such cases I have used lead, but not in sufficient quantities to enable me to recommend it Iodine has been recommended 2 or 3 doses 3 times a day Nit. sil. languinaria & digitalis When in the progress of the disease the circulation becomes much affected the pulse frequent, soft, flowing with occasional intermission respiration high frequent and laborious, with a bloated and sometimes analogous to # a livid countenance, the blood root has done more than any other remedy not failing in any instance to give relief & palliate sympt & in some cases the relief has been permanent. I gave the bloodroot repeatedly, the last spring, 1815 to my patients in the whooping cough. To a child a year old 5 to 10 or 20 grs of the dried root, according to the urgency of the case, infused in 6 or 8 teaspoonful of boiling water. Give a teaspoonful every hour, until vomiting is produced or the patient relieved. Children Sometimes the dis. will be very mild and yet leave the system in such a state that a slight subsequent disease will carry off the patient e.g. in 1815 the dysentery attacking children would often be very slight and yet would carry off every one who had had the whoop. c. in the spring. The attack would be mild and insignificant of dysentery and yet the pat. would go into a [illegible] very speedily like cholera Elaterium has been recommended I shd be cautious in trying it except in very vigorous children I can speak with confidence of arsenic. Excepting occasionally prussic ac. I know of no remedy which so completely cures the wh. cough except prussic acid in some cases. Case child 2 gtts night & a [illegible] in a weak countenance pale, eyes dull face bloated muscular strength weak muscles soft & flabby Parents much [illegible] cough gone recovered colour & strength upon bark I have known several such cases and have known no ultimate injury result from this practice Yet parents are afraid 156 who had the whooping cough that spring were very liable to be carried off by the dysentery of the following summer none died in 1815 of the disease but many in consequence of it, with hydrocephalus and dysentery Prussic acid dose 1/3 of a drop to begin with and arsenic occasionally cut this disease entirely short; and these are the only articles which I have known do so, without leaving a vestige of the disease behind. The former is a dangerous article to use, from its want of uniformity and strength Fowler’s solution of arsenic gtt more [illegible] is safe but does not answer so well in the first stages. If it makes the patient feeble livid bloated & with swollen lips etc. it must be stopped & perhaps bark administered. It has cured the cough in the second stage. Dose 1 drop 1 or 2 drops twice a day. Sometimes is only palliates Case. June 1815. A child of Capt. Totten’s a boy of 5 yrs of age rather full habit had been affected with the cough for a fortnight before I saw him I found his pulse very frequent soft convulsive & with intermissions face swollen and livid, circulation much increased on slight palpitative [illegible] motion of the body in the symptoms aggravated to an alarming degree by a paroxysm of coughing. Previous t the disease a remarkably even tempered and pleasant child he was not on the contrary very irritable. Trifles irritated his mind, and when irritated, all the symptoms of his disease were aggravated. He took an emetic of ipecac, with The sequels of this disease are numerous Sometimes the heart is affected as above and continues so for years. Sometimes the glandular system is affection. Sometimes the lungs. There is a lady in Philadelphia who had (under my care) suppuration of the lungs whoop. cough now healthy hence never despair The stomach and abd. visc. are sometimes affected in a chronic way requiring dandelion mercurials hop [illegible] etc. It is very tedious to attend children in the chronic stage an account of the excessive irritability When bath recommended Cold bath doubtful. I have known patients killed by being brought from the country and plunged in the sea bath “Good speaks highly of rhus [illegible]. It is given to produce a distinct action on the system which shall overcome the diseased action. It determines powerfully to the surface and has a powerful exciting effect on the blood vessels while it does not produce a determination to the brain. I should not recommend this article and it is so uncertain in its effect. On one person it will have no effect at all, when in another it will cause swelling of the eyes, blindness, fever, & great irritation 157 but inconsiderable & temporary relief. He was directed to take the bloodroot every hour, as much as the stomach In relieved the violent symptoms would bear. It was continued for two or three days, and the palpitation of the heart was much abated, the circulation was less irritated, & the livid colour of the face was gone still did not cure When costive he was benefitted by full doses of cathartics. because the system was [illegible] deranged heart lungs etc. I considered the case a fatal one and expressed that opinion to the parents. The cough and other symptoms continued though in a less violent degree disease chronic an epispastic was applied to the chest very irritating (changed clothes often in the day [child] run upon various subjects) Patients strength began to fail and tonics were given white vitriol bark cantharides Finally the patient refused to take any medicine and was left to his own appetite called obstinately for it took cake for food for several days then baked pears then [illegible] Afterwards recovered but was unable to run “for some years” without a palpitation If this disease should again prevail I think I should atropa belladonna as a prophylactic. As the disease continues the stomach may become very much debilitation and require compd powd of [contragerva] cat carilla etc. etc. “Ledus palustra are narcotic” It is not certain that the dis. did not exist before It may have existed before but no general account given of it. It may have been known in diff. places by diff. varies and it [illegible] have been known than the diff names meant the same disease Diseases are not apt to appear suddenly. Still at this period, there [illegible] cause operating for the increase of the dis. Belly usually large and limbs small Joints unusually large Often morbid cravings of appetite Yet the same causes operating in a higher degree produce cretinism There is no difficulty in recognizing the disease You will be struck at first sight with the large size of the head the blue [veins] of the forehead paleness of countenance as you cast your eyes down you will notice the large joints 158 Ricketts This disease according to Underwood was first noticed in England in the year 1628. It is said to have immediately succeeded the increase of manufactures, when people left the villages to settle in large towns, where they wanted exercise and a pure atmosphere Children are rarely attacked with this disease earlier than the sixth month and not usually until after that period. The symptoms are soft flesh muscles & cell. sub. relaxed general relaxation of the system paleness of the countenance unless the face is flushed with fever, which when it exists is of the hectic kind a fever of irritation pulse, usually quick and feeble, tumefaction of the abdomen appetite and digestion bad tendency to acidity veins of the head [illegible] and blue the sutures of the head not firmly closed head large fontanells unusually open joints large in bad cases all the bones of the system enlarged & softened One effect of the disease is that the teeth are cut later than usual. Ricketty children are usually precocious in intellect. Their mental faculties are developped more early but are not capable however of so much improvement, as those of others. Evolution of the mental faculties does not proceed with the tardy progress of the assimilating function The child learns to [illegible] very early and exhibits an acuteness of intellect beyond his years with the exception however of those cases so severe as to have a tendency to cretinism It is a common saying that very forward children are not likely to live long and the precocity of scrofulous & rickety children may have contributed much to the production of this impression. Too much heat may produce an indirect debility Undoubtedly aff. the brain & nervous system Give mercurials occasionally Do not produce salivation and do debilitate by mercury Frictions are very efficacious exciting the skin The reasons why friction are not more successful is that they are not perservered [illegible] the al. can. etc. The cold bath is the only strengthening remedy which acts suddenly No effect can be produced by any medicine equal to the astonishing effect of exercise & amusement in many cases of chronic aff. of stomach & bowel. 159 The causes of this disease as in some instances a predisposition transmitted from debilitated parents sometimes a syphilitic taint of the parents In others bad nursing the children being kept wet and dirty and confined in close & damp apartments or if the child has been carefully fed and kept clean debility produced by confined air too great warmth, too great variety of food and as some think too much saccharine matter in its diet. Inanition may be a cause. The disease prevails among the Alps and is perhaps there caused by the combined influence of cold and moisture This is a disease of debility nearly allied to scrofula & cretinism affecting the viscera of the abdomen generally, the lymphatics and the [isseous] system. The chylopoietic viscera are probably first and afterwards the mesenteric & lymphatic glands generally the indications are to give tone to the system and excite healthy secretions The diet should be dry and nutritious and such as is not only easy of digestion but rather stimulating and the bowels kept open by cathartics which act on the secretions. A dose of calomel with a little ipecac will be useful. The cold bath should be used every day Take the child out of bed in themorning bathe & return. If the Cold bath of salt water is [illegible] tonic patient be very feeble it should be begun with at of a temperature of about 80 [degrees] and gradually used colder The child bath is equal to all other remedies It is more tonic if made of salt water As a substitute for exercise, frictions will be very useful But exercise in the open air should be like whenever the weather is good in a carriage or on horseback and exercise should be so managed as to afford amusement and mental The [guephalin] [polyapt] & also the gr. marg. (which is less odorous) are also used Their agreeable odor if there is no other advantage will prove grateful stimulus & promote healthy secretions Take the child out of bed and plunge him in water (about 70 at first) and replace him in bed Yet in exhaustion of fever the cold bath gives a shock from which the system will not react but yet in the debility the cold bath is highly beneficial whether we can explain it or not. It may be necessary to vary the tonic And it is desirable to have a variety of tonics to [chorea] from also carb iron & tinct. carb. iron ac. fer. alkaline solut The sulph. zinc is not inferior to iron and is not subject to the inconveniences of iron not producing inconveniences Mosely’s sol. The compd tinct vitr. although apparently [illegible] is yet certain in operation and has been long used in this vicinity A tinct. of potash is thought very useful to rub the body with. It is a popular remedy & has sustained its reputation in this neighborhood for many years Lime water made of caustic lime is more tonic than the carbonate That made of shells is thought better being pleasanter than that made for stores probably not as pure but containing muriate of lime. Be careful to see that the shells are thoroughly burnt so as to fall in powder when 160 stimulus by the sight of scenery vegetations, flowers etrc. The patient may even be benefitted by being carried in the arms into the garden and amused in this manner. It must not be forgotten that this cheerful excitement has a powerful effect on the secretions. Feather beds should be prohibited. They are too enervating, and hard ones should be used in their stead. Beds made of the sweet fern (comptonia [asph??folia]) are popular & do very well. They not only from their hardness check the profuse perspiration of the hectic diathesis, but correct the acid smell of the sweat which is very common. IN general heat should be avoided as too relaxing I have rarely failed of curing the disease by the cold bath as the principal remedy, using tonics however as occasion may require. The tonics which we may use are sulphates Phosp. & mur [illegible] 3-10 grs of zinc & of iron muriate of iron martial flowers of iron etc. and the plan has been tried of applying finely powdered bark eternally in a quilted jacket of flannel. It is difficult to give bark in substance to small children. Astringents may be indicated & there is often a degree of acidity so great as to indicate a free use of absorbents The alkalies as pearlash may be beneficial internally & frictions with pearlash & water zfs to a pint may be recommended. Of late iodine has been given in doses of from 2 to 4 drops of the alcoholic tincture 3 or 4 times a day, given mucilage or other convenient vehicle. This article when persevered in has cured a great many cases. It should be [given] at first in small doses & the quantity be gradually increased or a disgust towards it may be created Phosphate of [illegible] was popular Forgetting that the deficiency of [osseous] matter may be defect in the action of the secretions Though the theory was wrong yet the practice was found beneficial absorbents Give a solution of the acid of about the strength of lemonade The phosporus is preferred to the phosphoric quenches in the water you will then have, not as is too commonly the case merely smoky water but lime water of full strength These preparations are called tonics by Good called stimulants (too loose as use of the word) Long before I had any explanation in [illegible] I thought I observed that these articles created a susceptibility to the operation of tonics apparently as generating excitability 161 It has been supposed that the proximate cause of this disease is a deficiency of phosphate of lime with bones but this is an effect, caused by want of action as those vessels which secrete this substance. The proximate cause, as it is called, is in this case the disease itself. In consequence of this notion burnt bones have been much prescribed. They are probably useful not as supplying the matter of bone but as an absorbent & perhaps as a tonic Acids especially the phosphoric have been given. Phosphate of lime has been used with benefit muriate of [illegible] and barytes were formerly much prescribed. The worst cases are those of children born of syphilitic parents for these tonics mercurials and the cold bath will also be the treatment. I give them corr. subl. 1/30 gr with no injurious effect Nearly allied to ricketts and often as sequel of it ricketts often running into it Sometimes appears with ricketts sometimes afterward Ricketts occur with the year. Scrofula occurs later. Ricketts children are more generally of a scrofulous temperament The tendency may exist in the parents and yet be developed only in the children from the causes of bad food [illegible] pain etc. These swellings may continue in children of 5 or 6 [illegible] or within the year with little or no change but increasing of size in spite of poultices filling the whole neck I have found poultices apparently injurious promoting the relaxation but blisters would stimulate and bring on a suppuration. The pus will not be healthy but curdy and whey like The edges will be ragged, not unite readily, and will leave a bad scar. Scrofula, ulcers are said to be distinguished by a smooth overlapping margin. the disease may continue for months and years with little or no change of it does not attack a part essential to life as the lungs, producing tubercular consumption attacking the liver producing a peculiar atonic infl. I have seen cases of scrofula that were [entonic] They were injured by tonics and benefitted by cal. and ant. They would have borne bleeding 162 Scrofula This is a disease of the lymphatics and affects persons of a peculiar temperament this temperament is characterized by a fair, thin, translucent skin, light hair, blue eyes, sometimes black hair and eyes delicate fullness of lips & nostrils usually texture of skin and cellular substance general laxity of muscular fibre usually delicate organization mental faculties developed early on in ricketts. Person who have been affected with ricketts in infancy are after affected with scrofula in after life. This peculiarity of constitution, when a morbid action is superadded, gives rise to the following symptoms First small swellings appear about the neck, slow in their progress & with an imperfect suppuration. Small holes form in the swelling and discharge a subpurulent, watery and flocculent fluid. These scrofulus ulcers when fully formed are distinguished by smooth spongy and overlapping margins & by very lax granulations. The disease forms tubercles upon the lungs, liver kidnies & ovaria & causes a great enlargement of the mesenteric glands This morbid condition and action may be transmitted from parents to children. It prevails especially in cold and variable climates exists most in large manufacturing towns where it is caused by bad food and air, want of cleanliness all of them debilitating causes It is sometimes also in persons predisposed, a sequel of other diseases particularly of small pox, hooping cough & measles Treatment. more may be accomplished in the treatment of scrofula by diet, exercise, sea air etc. than by remedies. Scrofulous swellings should be treated by Avoid cold vegetables & watery diet give animal food articles containing nitrogen as infants are said to abound more in albumen and adults to be [illegible] “Iron zinc copper silver tonics & antispas. are useful” “Conium 2, 3, 4 grs with carb. fer. 10-20 grs” # “I have used with advantage mur. lime 3-4 drops increased to a tablespoonful & also mur. [illegible] 3-30 drops given in milk & water or in coffee. They are tonic & act on the lymph. & gland. syst.” Articles containing [illegible] In [anthelmint???] vesicular [illegible] F. idealis ([illegible]) (sea cabbage) has been given for worms and some families learn their children to cut it A mucilage may be made F [vesiculosis] [illegible] which with bran has constituted a popular poultice for scrofulous tumours When there is loss of tone & an ill conditioned discharge cantharides with opium is a valuable excitant Never continue any remedy after it debilitates by exciting disgust and nausea Mercurial plaister of the shops (gum ammoniac & blue ointment equal parts) has been much used especially for scrof. [swell.] of the joints In these [illegible] become extensively effective and become spongy A man at the westward was very celebrated for curing scrofula. He used wild violets but was not particular as to which species he used 163 blistering van Heuvel’s child a round of remedies had been tried [illegible] Occasional purging with calomel and rhubarb and ipecac in a pill will be useful Preparation of iron, carbonate of iron with conium etc. muriate of [illegible] 3 drops or 6 and barytes in [illegible] you give a teaspoonful iodine scrophularia mar. [Cistus] Canadensis uva ursi Mr Daggett Havanna Dublin Eliza Collis Vide p. 209 Iron no prep. perhaps are better than myrrh mixture or Jenkins’ pills (carb. per. [illegible] camph.) “Bark & quinine” Different preparations of [illegible] & barytes # Now superseded by iodine. I have seen more powerful affects produced by 4 dr. tinct. iod. persevered in a long “5 to 20 gtts within the year 2-3 gtts ter in die” Various vegetable articles I think very highly Rock rose or Cistus Can. (Helia [illegible] [pity] it is changed) Some years since a person went to Long Island to be cured of scrofula to a family famous for curing scrofula returned much benefitted should his remedies they [illegible] [illegible] & [illegible] always used than afterwards, when [illegible] [illegible] from Havan. neck filled up cured by [illegible] had been salivated W. I. without benefit Eliza Collis scrofulous cough much [illegible] cured by [cistis] vide p. 209. Scroph. maril. has been popular has been much used by empirics I have seen it sold at a great price brought from the west a very common plant It has been celebrated for accelerating parturition probably with out foundation The article has probably little or no power. Yet it is advantageous to know such articles in order to [illegible] [illegible] Two entirely different diseases but are classed together and may be treated together “H. externus is correctly named hydrocephalus” “No fever ordinarily attends. The disease consists in loss of town in the absorbents” Of late iodine has been recommended [illegible] two years since I was called to a patient with had enormously distended [illegible] [upon] gr. cal. & 2 drops tinct. iod. [illegible] recovered Tinct. canth. Face pale and bloated child sleepy and [illegible] I know one child who recovered, but at at the ages of 5 or 6 years died of H. internus. If the patient recovers he is more liable to the acute disease afterwards. Puncturing the membrane has been tried with success, and the application of bandages then supporting the child. It is said that puncturing of the pressure has [illegible] 164 Hydrocephalus Divided into two species externus and internus In H. externus the water is formed between the membranes of the brain (between the brain and its membranes?) In H. internus it is in the ventricles of the brain H. externus make its appearance at birth and is usually born with the child. # In its ordinary form it is fatal (It is almost always fatal when it makes its appearance immediately after birth and always so if born with the child) Stimulating and discutient applications to the head have been recommended. Epispastics are said to be serviceable. (Blisters have been found serviceable they should be kept up for a length of time) Mild mercurials cal. or blue pill & the muriate of lime or sometimes [illegible] pressure by bandaging . If the disease is accompanied by rickets the cold bath is indicated and has been found serviceable I have known one child recover from this disease and other who has been mending under medical treatment for 2 years past. I do not know whether it recovered # H. externus appears to be nearly allied to those watery tumours which affect the spine. In consequence of a partial opening of the sutures of the cranium, or the absence of a portion of one of the bones the dura mater and scalp are protruded by the pressure of the contained water & form a swelling on the outside of the head. Puncturing this tumour is suddenly fatal (is as fatal as the same operation performed on the tumor of the spine. Arachnoid inflammation, arachnitis, apoplexia hydrocephalica (Cullen) encephalitis phrenicula of Rush cephalitis profundu of Good We might multiply [illegible] but perhaps this is sufficient The disease different in different cases A great deal has been written and great deal of confusion exists “In this species of hydrocephalus the effusion of serum is into the ventricles of the brain. This serous effusion is the effect of the disease and not the disease itself & hence it may follow diseases of various kinds. I consider the name very improper” # “The vomiting if it cannot be ascribed to improper food in the stomach is an important symptom in the diagnosis” 165 Hydrocephalus Internus acutus Under this unfortunate name I propose to treat of all those cephalic diseases which are less violent in their action than phrenitis (or are less inflammatory). I shall principally confine myself to the disease as it appears in children “Symptoms different in different cases” The disease commences with the following symptoms (one form of the disease is well described by Dr Quin) vide [illegible] vol 2 p. 315 The patient is languid inactive and drowsy more or less feverish at times apparently free from any complaint (drowsy & peevish at intervals easy and apparently free from any complaint) The appetite is poor and irregular (week) & (Nausea &) in many cases vomiting # occurs once or twice a day. The skin “Exacerbation towards [illegible]” is generally hot and dry (towards evening) and if a perspiration occurs it is partial. Soon after these symptoms. The patient is troubled with a headach. The seat of the pain varies in different cases, sometimes it is confined to one side of the head (Soon after these symptoms commence the patient is affected with a sharp headach either in the fore part or crown) It is a common observation that the headache alternates with the affection of the stomach, the vomiting being less troublesome when the pain in the head is most violent. The pain occasionally attacks other parts of the body (& sometimes principally confined to the back of the neck and the space between the scapulae) At this period the patient is averse to the light, cries much & sleeps little While asleep the patient shows # “The tongue is commonly clean & in this respect this aff. differs from remittent bilious fever, in which the vomiting & febricula are attended with a yellow fur upon the tongue” One side of the face body one arm or one leg more affected or moved often is perhaps a severe a pathogen sump. as any other. This is an indication of paralysis I have known [illegible] patient recover from paralysis 166 signs of uneasiness grating grinding the teeth. starting and screaming in sleep as if terrified. The bowels are usually constipated though sometimes relaxed. The pulse in this early stage does not indicate much danger (These symptoms however are subject to great variations). These symptoms are succeeded by affections of the eyes. One eye is turned in ward to the nose its pupil is dilated The pupil contracted in this early & dilated in the latter stages. Sometimes both eyes at the same time are affected in this way both turned inwards & both pupils dilated. In this stage the vomiting becomes more constant and the headache more excruciating, the pulse is frequent and the breathing quick. # If these symptoms supervene to typhus fever, the pulse becomes more slow Exacerbations of fever take place towards evening. There is often a flush upon one cheek (flushing is usually confined to one cheek) Perspiration if it appears is usually confined to the head and chest. A discharge of blood from the nose at this time relieves the symptoms of fever (& removes the flush from the cheek) for a time & any favorable symptoms. Delirium often takes place at this time and is violent in proportion to the age of the patient All this time the disease is undergoing a change. As the disease advances the pulse becomes more slow and unequal & the patient becomes less sensible to (the pain in the head) his sufferings Lethargy succeeds the disturbed sleep and restlessness of the early part of the disease. The strabismus and dilatation of the pupils increase & the eye loses its sensibility Loss of vision (The patient after sleeps with one or both eyes half closed) The patient in this stage often takes medicine & # “Even in this stage patients have been cured by the strong impression on the system made by tartar em. pushed so far as to produce colic” vide infra Sometimes when hemiplegia takes place the disease puts on a chronic form In the 167 sometimes food will sometimes however he obstinately refuses to take any thing. The bowels for the most part continue costive. # To these symptoms succeed a quick small pulse (almost imperceptible) bad symptoms in the last stage sure forerunners of a speedy dissolution (a difficulty of breathing in many cases the flushing of the face is succeeded by extreme paleness sometimes in this stage petechial eruptions appear on various parts of the body & the patient dies in convulsions or sometimes a hemiplegia takes place two or three days before death The disease sometimes runs through its stage in 4 or 5 days at other times it requires as many weeks. The dilatation of the pupils in some cases does not take place until the last stages & perhaps sometimes not at all. In all cases the proper treatment should have been pursued before strabismus, blindness or coma takes place, because very little is to be done afterwards. A constant rolling of the head & moving one arm and one leg are among the most important early symptoms which indicate a dangerous affection of the brain) The disease sometimes puts on the form of an intermittent. When the disease has terminated in effusion the case is probably always fatal. much dissatisfaction after existed When an ordinary fever terminated in hydrocephalus thinking that the phys. was mistaken at first “I think this disease is rarely an idiopathic affection. It supervenes upon other diseases & generally depends on disease of the stomach & bowels” The disease when from ext. violence may exist without any [pathognomic] symptom 168 Causes external violence teething worms Other fevers forming a crisis by effusion into the ventricles of the brain. Typh. fev. & dysent. in children terminate in [illegible] I have known more than one instance in which it followed [illegible] of hip joiont This is very rarely an idiopathic affection unless it may be considered so when it arises from external violence Vide L. J Pringle on dis. of [illegible] When it does arise from external violence it rarely puts on the same symptoms or the same appearances after death All the diseases of children from infancy are liable to terminate by hydrocephalus & hence it is important to examine all the symptoms which may indicate a determination to the brain & check the tendency if possible Case A girl 14 years of age, had symptoms of affection of the brain from a fall upon the occiput she complained of pain in her head for two or three months before she died & occasionally had regular epileptic fits [illegible] [mouth] The pain the head was relieved by cupping and epispastics to the head, but she finally died in an epileptic fit On dissection the dura mater under the cranium, where the injury had been received was thickened and the vessels were injected with blood. The ventricles contained half a pint of water. Dropsy in the brain Yet the pat. had no dilatation of pupils etc. The dis. put on the appearance of epilepsy occurring once a month. More common in some families than in others 169 Causes. Hydrocephalus is a disease nearly allied to with scrofula & like that seems to run in families. Delicate children in whom the mental faculties are more early developed are more subject to it. Hence the common observation that the child is [illegible] forward that it will not live long I think persons of a scrofulous habit are more subject to this disease & that of the hip joint When there has been no local injury to the brain, the disease commences with affection of the bowels, or it is a sympathetic affection from disease of the bowels In the progress of bowel complaints in children, the [illegible] and the small veins become turgid. This enlargement of the vessels seems to invite the blood to that part. In consequence of this child may die with symptoms of hydrocephalus, from the turgescence of the vessels, without any effusion into the ventricles In typhus fever, in dysentery and in other bowel complaints of children it is not uncommon for children to die with symptoms of hydrocephalus It is a good symptom in hydro. to have a discharge from the [sch??der???] membrane 170 Diagnosis “In its early stage, this disease is scarcely to be distinguished from remitting fever When from the anxiety of relatives & of the physician, a diagnosis is eagerly desired, the following circumstances may perhaps assist in forming a judgment If there is occasional vomiting, with febricula the tongue at the same time remaining [illegible], there is reason to apprehend that the primary irritation has its seat in the brain and that it will prove a fatal case of hydrocephalus. But if along with the fever and vomiting the tongue is covered with a thick yellow fur, we may hope that the complaint is confined to the digestive organs and that the disease is nothing more than coler or remittent fever.” Ed.reviewer Diagnostic symptoms between idiopathic arachnitis or cerebral fever, and infantile remittent or fever from intestinal irritation choler In cerebral fever the abdomen is flattened, not tumefied but in intestinal fever it is tumefied. In idiopathic cerebral fever the secretions of saliva and that form the schneideran membrane are diminished. Unless complicated with aff. of muc. m. which is rare. In cerebral fever the tip and edges of the tongue are red In intestinal covered with a thick fur. In cerebral fever the pain in the head is severe and excruciating; in fever from intestinal irritation it is obtuse. # the sides of the head, back of the head on the forehead Perhaps a constant rolling of the head & movement of an arm & leg are among the most important symptoms Different opinion ben entertained about the nature of the disease Some have been so anxious about determining the exact nosological nature of it disease as to refrain from prescribing until the first stage has gone by. Prescribe for the symptoms at all events and make up your mind about the nature of the affection as fast as you can. Too much discrimination cannot be exercised & cultivated yet where we cannot determine the exact nature of the disease we had better treat the existing symptoms & the obvious indications # It varies in scrofulous constit. there is no such state It may approximate in some cases And I might cite the opinion of 20 others The [illegible] it is sometimes entonic & sometimes tonic. It more frequently [illegible] determined Why shd not fevers terminate in the brain as well as [illegible] 171 In intestinal fever the patient more frequently directs his hand to the nose & about the face in cerebral puts his hand to his head # In cerebral affections the head is hotter than the abdomen; but if the disease originates from the bowels the abdomen is the hottest. “There in a very few cases seen picking at the nose in cerebral fever but in general the rule holds good” “The state of the bowels is not pathognomic” Dr Beddoes thinks the disease belongs to inflammations & that at an early period he should be inclined to bleed as largely as in pneumonia # Dr Withering observes “in a great many cases if not in all, congestion or slight inflammation are the precursors of aqueous accumulation Dr Rush thinks that instead of being considered an idiopathic dropsy, it should be regarded only as an affect of primary inflammation or congestion of the brain “Dr Rush says” It appears that the disease in its first stage is the effect of causes which produce a less degree of that inflammation which constitutes phrenitis & that its second stage is a less degree of that effusion which produces serous apoplexy of the brain Dr Darwin supposes torpor or inactivity of the absorbent vessels of the brain to be the cause of H. internus Dr Whytt in his treatise on the disease observes that this and every kind of dropsy depends upon the fact that more fluids are thrown out by the exhalants than [illegible] the absorbents take up I chiefly depend upon calomel for a cure if it cause too much evacuation check it with opium There is no evacuation from the brain therefore the disease must be overcome by altering the secretions counterirritation etc. Bleeding with leeches from the temples seems to translate to the surface and give relief vide John Hunter. Case young man apparently as desperate a cure as ever I saw not scrofulous we concluded to try tart. emet. gave it without much weight in about 8 or 16 hours he complained of violent pain ion the bowels and all the symptoms of the head were relieved [illegible] “Irritant to the schneiderian membrane in the last stages are recommended by Dr Malachi Foote of N. Y. in the Med. Rep. for about 1810. Turpenth min. 1 gr. with liquorice 20 grs [apreynum] [myrici] ipecac etc. are the best [stermentatories]” 172 Treatment Evacuants Bleeding general & local cathartics calomel and jalap gamboge Counterirritation local bleeding cupping epispastics behind the ears and to the whole surface of the head Salivation should be induced but cal. often relieves without altering the secretions There has been a difference of opinion as to the application of epispastics to the head. If venesection be indicated they should not be applied until after bleeding. I prefer cupping and blisters to the back of the neck and behind the ears I think some advantage may be derived from applying to the spine ol. orig. ol. capsc. etc. Where considerable entonic action has existed I have cured this disease by giving tartar emetic until colic was produced. give perhaps a grain & continue its exhibition until the symptoms abate # “gr doses every 2 or 3 hours” Sneiderian membrane dry snuff malachi root Irritants applied to the schneiderian membrane have cured the disease in its last stages Rx 1 part turpenth mineral & 10 parts powdered liquorice for a [ster??tatory] Green tea is sometimes given In the progress of the bowel complaints of children the sinuses may become enlarged & a determination of blood [illegible] to the brain and produce symptoms of hydr. I have known pat. apparently die of hyd. & yet upon dissection no water be found in the [ventricles] in this case some say that the water was absorbed in death this is entirely improbably. Certainly many of the symptoms of hydr may be prod. by other causes e.g. excessive doses of narcotics is stramonium belladonna It shd be remarked that many cases supposed to terminate in hydr. in cases of [termination] in volvulus “All the diseases of children are peculiarly liable to terminate in hydrocephalus. Hence the importance of caution on the part of the physician. He should examine all the symptoms to check the first beginning of determination of diseases action to the head V.S. keep the bowels open blisters behind the ears cupping leeches” 173 Hydrocephalus from bowel complaints If in the progress of any of the bowel complaints of children morbid action should be determined to the brain, Epispastics should be applied behind the ears and irritants to the feet Cathartics are useful to obviate this determination. # In some cases perhaps the determination [marise] from nervous irritation. In such cases the tepid bath gives relief “Strong green tea” Some physicians of respectability have in formed one that they have used digitalis in hydrocephalus with very good success. I have not used it myself but should consider more adapted for that form of the disease which arises from irritation, than any other Hydrocephalus from disease of hip joint. Child of Ezra Hotchkiss child of Horace Edwards. “I have known hyd. alternate with disease of hip joint Case Narcotics etc. till suppuration” Afterwards died of hydrocephalus # I have cured a patient by giving him calomel and lemon juice in sufficient quantity to move the bowels. It increases the secretions and improves the tone of the bowels “I have seen a case in which the child fell 8 or 10 feet upon a pavement & broke his skull like a squash shell yet he recovered in 2 weeks and did well. When the fracture is so extensive there is less danger of compression of the brain” The same case? Hyd. from injury by a fall is not common in young children the sutures are not firmly closed (the bones are softer & more yielding)( # He had other severe wounds as a compd fract. of the radius yet he never suffered his head 174 When the disease is produced by violence Depressions of the cranium in children from blows or falls are not of course fatal though dangerous. A child four months old fell head foremost upon the hearth striking upon the vertex. The head was much flattened & the parietal bones bulged out on each side. The child did not suffer much from the injury. The bowels were kept open by mild mercurial purgatives. In these the head assumed very nearly its natural shape. A boy of eight years fell six or eight feet and struck his head against a stone A depression of the cranium was made larger than the bowl of a spoon. He suffered very little inconvenience from the injury # There is less danger when the skull is so much fractured as not to cause pressure upon the brain If a child has received a fall we may apprehend danger from the following circumstances. If the fall has been upon the occiput the brain is more commonly injured than if the face is upon the os frontis. If the child vomits after the fall and is very sleepy there is danger that the brain will suffer. Treatment If the child vomits or is comatose after the fall upon the head and there is no wound that bleeds the patient should lose blood and take a dose of calomel, one or both according to the urgency of the symptoms & the death of the patient. All the exciting causes of fever should be avoided and the patient kept as quiet as maybe. The symptoms should be carefully watched and if at anytime there should appear to be a tendency to an affectation # for local bleeding is as important a general bleeding “[illegible] all causes of irritation, as light noise heat, food. Keep the pat. perfectly quiet” “Apply an epispastic behind the ear, or better upon the injured part.” “Blisters are very useful” “Use counterirritation & the tepid bath” # In torpor of the br. [illegible] al. can excite the latter may excite the former and excessive action in the former may be translated by it act on the latter “Give strong cath. cal. gamboge jalap etc.” “Afterwards give cal. in small doses as an alterative If it causes too much evacuation check it with opium” “In N. Haven we have followed Abernethy’s plan of treating infl. of brain for 40 years” 175 of the brain the patient ought to be bled & leeches or cupped. # The bowels should be opened with calomel and small doses of the same remedy frequently given as an alterative After depletion epispastics may be applied behind the ears and upon the part of the head where the injury was received. There is no outlet to the brain & consequently more evacuants are needed than in most diseases Frequent cathartics are useful as evacuants and also to translate action from the brain # When effusion has taken place the case is probably always fatal Yet I have had a pat. with dil. of pupils, who cont. so & paralytic for months & finally recover Vide p. 200 The treatment consists of local applications A variety are used One of the best is [illegible] zii alc. zi An equally good or a better application is seneka oil but the smell is disagreeable. Cold water is applied but though it relieves the pain and the insupportable itching it is doubtful whether it is of any permanent benefit Basilicon [illegible] [illegible] absorbents to ulcers 176 Chilblains Pernio This is a local affection to which children and old people are most subject. Some are much more liable than others. [illegible] [illegible] more liable. The parts affected are the toes heels fingers, hands face, ears and with ladies who wear short sleeves in winter. It is caused by exposure to extreme cold & to cold & damp air & on the feet, more especially by walking through melting snow. It is most common in the early part of winter This affection should be prevented by avoiding an exposure of the parts to the air, by keeping the hands warm with soft leather gloves & by keeping the feet warm with stockings and shoes The skin of the part affected becomes tumefied and hard & of a deep purple colour, there is a pungent pain in the part accompanied with an insupportable itching; & these are often so great as to prevent the patient from sleeping. If the disease advances, the cuticle breaks and discharges a thin fluid. Sometimes a deep ulcer is formed The treatment for the first stage should consist of stimulating application as if for a burn. I prefer oil of origanum alcohol & seneca oil are good applications. Spirits of turpentine will ordinarily do well, though in some idiosyncrasies it acts as a poison. Cologne water may be applied or alcohol two parts with one of ol. orig. # For the ulcers you may use the oxygenated ointment ointment of red precip. citrine oint. # or apply a plaister Dyachylon or Noel’s Not being able to have any fire on board for some days [illegible] to pain of a neuralgic kind as [illegible] were a toothache One of the best applications is a cataplasm of stramonium seeds give internally opium narcotics & stimulants Apply [illegible] & narcotics Followed by no infl. to supp. etc. 177 Painful affection from cold We sometimes meet with a painful affection of the feet without discoloration, or any other visible mark, which has been brought on by long exposure to cold without freezing. Sailors coming upon our coast from the I. in winter, from a warmer climate are liable to it. The affection may be a very painful one and give great uneasiness both night and day It is relieved by the external application of stramonium & epispastics or rubefacients, and fomentations Cathartics and opium may also be given internally. Singular effect of cold in Wm Daggett Burns are dangerous in proportion to their extent [illegible] young physicians are called to prescribe for burns it is important for them to treat them in the best manner About 30 years ago a great controversy existed in England between those who advocated [stimulating] In recent cases stimulating or exciting applications are the best provided the burn is not very deep. About 30 years since spts turp. were much used. It in some case and these are not very rare Case myself [water] boiled over into my shoe I immediately poured spts tupr upon the stocking then took off the stocking applied a cloth dipped in spts turp. put on a dry stock. & boot rode out of town and suffered My father was a man of florid complex. & thin skin He was burned in n a similar manner Ol. orig. Linseed oil is smooth mixed with limewater alcohol or proof spts good when the skin is [illegible] off Others use camphor Others stramonium in ointment contain what [illegible] when the article s off Carrot poultices etc. exclude the air Cotton does well except when the cuticle is off if it is used then you had better smear it with oil 178 Burns This subject belongs more particularly to surgery, yet as burns occur most frequently among children, and you may be suddenly called in on such an occasion, when it is important that a remedy be speedily applied. I have thought proper to make some remarks on the subject. For the treatment of burns very different modes have been recommended. A long controversy was carried on in one of the English journals with respect to the phlogistic or antiphlogistic treatment, one party being in favour of cold applications in cold water and the other of stimulating ones as spirits of turpentine The truth seems to be that in adults where the injury is not extensive and the powers of life are strong cold applications do well, but they are dangerous for children especially if the injury is extensive. Burns upon the abdomen will not admit of cold application even in adults It is necessary that reaction take place If there be no reaction of the system, no pain, no inflammation the child dies. The cause of its death is the irritation of the nervous system, extended to the stomach, & hence the death is preceded by cold extremities and vomiting Where cold application are proper such applications may be made as scraped potatoes, cloths wrung out in cold water etc. But if it is necessary to produce reaction and inflammatory action stimulating remedies must be used. And we know from experience that these remedies do effect a speedier cure Cold applications may do well if immediately e.g. dip a burnt arm immediately into cold water. But stim. app. are better. I have tried both. Cold applic. very dang. in extensive burns of children Case scarped potatoes no infl. livid appearance of the burn extrem. cold [illegible] death In such cases apply stim. app. & give ether, elix. [illegible] etc. etc. In these cases the child dies of irritation not infl. It seems to be necessary for a regular [course] of continuity of action in infl. & suppuration The best and mildest application as has been proved by experience is petroleum or seneca oil In one case I tried the experiment of applying seneca oil upon one hand & ol. orig. upon another (both being known alike) one hand was easy the whole night the other painful (the burn was a very extensive from the clothes taking fire) In the suppurating stage use 1 part seneca oil & 3 parts cerate These cases are very troublesome to treat In the above case the system was exhausted by the extensive suppuration the bowels had to be kept open & large quantities of opium to be given. I gave columbo bark and various tonics and aromatics Turner’s cerate is a good application chalk may be sprinkled over it In the progress of the suppuration a pale flabby fungus almost like a blister and is difficult to manage I have applied a sol. nit. sil. also nit. sil. & laudanum [illegible] cop. sometimes after these I have succeeded with ac. op. in ointment green basilicon i.e. verdigris ground fine & mixed with basilicon But if you apply only applications after these caustics 179 The reason is that we apply to the part a stimulus less powerful than that which produced the injury and thus render the diminution of the excessive excitement gradual. On this principle holding the injured part near the fire is beneficial Another important indication in the treatment of burns is to exclude the irritation of the external air Hence the popularity of some applications as cotton. sweet oil etc. 1st Of stimulating applications. Spirits of turpentine will answer for a robust and healthy person but not for a slender & feeble one; and it must be remembered that from a peculiar idiosyncracy it is a poison to some persons. In general spirits of turpentine is liable to cause irritation and may be suspended by better articles. Being burnt myself a complete cure was effected without the least appearance of inflammation, by this article but in the case of my father such violent irritation was produced as to oblige him to desist from applying it A common remedy in this town is the oil of the origanum majorarum called burn oil mix ol. orig. zii with ol. oliv. zi or mix it with alcohol or cerate. Cloths may be dipped in the diluted oil and kept constantly applied Of late years I have used seneca oil and prefer it to either of the two already mentioned. In several cases I have tried both this and the ol orig. & found that the seneca oil relieved more speedily & with less irritation. I usually apply the seneca oil & the fungus [illegible] Apply rather chalk or fine alabaster or scorched flour The sooner you apply stim. appl. the better ol. turp. produces [illegible] etc. seneca oil does not Case a woman thief etc. etc. we rolled immediately in the snow was thrown by it into a state of syncope life almost extinguished was burnt universally except on the legs covered by the stockings was wrapped in sheets dipped in a mixture of ol. orig. & spirits 180 then cover the part with cotton to exclude the air. I let them remain till suppuration takes place, particularly if the skin is broken. When suppuration takes place, apply a poultice to the loose dressings and then apply simple cerate or a cerate made by melting together beeswax and lard and stirring in seneca oil while the mixture is cooling This last is an admirable application for burns Dr [Mons??] said he knew none so wild. It protects the raw surface from the cold air and keeps in the animal heat In the latter stages of the cure, the oxygenated ointment will be a soothing application A popular remedy is stramonium, used in the form of a plaister of the seeds or leaves. It answers well and I have known no ill consequences to happen from its use though it is said that in extensive burns it is dangerous Cotton is a popular application, used by itself For slight burns it will answer but if they are so extensive that suppuration is to take place, it should not be applied in this way Other remedies that are useful upon the principle of excluding the air, are the oils as sweet oil & lamp oil. Linseed oil mixed with one third part lime water, is especially recommended When suppuration takes place and the cicatrices do not form well, oily application should be laid aside and if there is considerable discharge apply absorbents, as plaister of paris, chalk & chalk & cerate i.e. apply chalk first & cover with cerate. Note from Dr Woodward of Wethersfield extracted from Dr A. Talcotts notes “Apply immediately spts turpentine to the inflamed parts and cerate of limewater & linseed oil equal parts on cotton to the vesications 2nd If pain & irritation ointment of stramonium 3d To prevent fungus Rx white lead a teaspoonful lard 2 tablespnfl. ft. ung. Orgrate or chalk and apply simple cerate over it. I have seen a metastasis at the end of a week to the bowels with diarrhoea & tumefaction or the bronchia with croup Treat with opium & bark Dr S. B. Woodward” N. B. I extracted this principally on account of the definite direction about the difficult treatment required according on the burned part is vesicated or not a point on which the above notes of DR Ives do not seem to be sufficiently precise 181 Should there be a fetid discharge from the burn, it may be remedied by pulverised charcoal. Sometimes the ulcers are very difficult to heal and repeatedly break out afresh A fungus may arise upon the part if so it should be touched with caustic. The eager of the ulcers may be touched with sulph. copper or nit. sil. chalk then applied and the whole covered with cerate. If the burn is on parts liable to unite in healing, as between the fingers and toes, care should be taken to prevent the union. A bad cicatrix is often formed which it is difficult to prevent or cure. Internal Treat When the constitution has received a severe shock and the extremities become cold and the powers of life being to fail, the system must be supported by stimulants & cordials & the excessive irritation relieved by opiates. Laudanum ammonia, spirits, alcohol ether are all good. To a child from 5 to 10 years old 15 drops of laudanum may be given; warm-applications may be made & warm aromatics drinks as ginger tea & mint water administered. Elixir paregoric is one of the best preparations of opium in such cases In a case in which a large quantity of sulphuric acid had been drunk by a boy who immediately afterward, ran to a brook and drank of the water. I merely give mild mucilaginous drinks & the patient being of a strong constitution recovered 182 Croup from p. 138 In what may seem to be the second type of patient may go off suddenly. If he throw his head back in order to enlarge the chest it is a bad sign I have found the treat. by tart. ant. so infallible in the first stage & in general so useful that I have not been tempted to desert it. If I am called rather late and find ext. ant. acting locally upon the stomach, I seldom succeed in curing the patient. Other emetics may be used when the excitability is worm out for [illegible] Calomel is proper in the latter stages, [illegible] the disease is partly broke up by antimony If the first stage is not interrupted [illegible] the child may be playful between the paroxysms and though the pulse is not affected, yet the second will surely come on In the second stage bleeding is to be first resorted to in order to prepare for emetics bleed even to fainting conjoining the warm bath for the same etc. Exciting and irritability [illegible] in this second stage do mischief. I have seen sanguinaria do much mischief. Even after bleeding purges is not advisable for as has been remarked there is a constant tendency in the system to the return of this inflammatory symptom Cal. may be given though if it act by the bowels it will be useless. I have seen bleeding and the vapour bath palliate the symptoms. Scarcely ever will the patient recover 183 Croup In the latter part of the last stage the child throws its head back. This is a dangerous symptom. Now the patient goes into the last or suffocating stage. The patient lies on its back struggles violently for breath countenance livid appears apoplectic and often goes into convulsions and in these convulsions sometimes dies Sometimes in this stage you may hear a flapping of the false membrane. This is sometimes thrown up and great relief is afforded and the friends think that all is over. Soon however in most even of those cases a membrane is formed lower down & the patient ultimately dies In this stage the metallic emetics have in a few cases succeeded The sulph. cupri & the sulph. zinc have each cured Cal. is recommended & may be used The cold both has been recommended It may be tried as a dernier resort. In the second stage after bleeding blisters shd be applied over the whole neck & chest Dr Hosack recommends bleeding from the back of the hand immersed in warm water After bleeding has succeeded in subduing the symptoms cal. & the warm bath shd be used 184 Croup This disease has been divided into acute & chronic but without much propriety Sometimes it continues for some time. I have known one case which continued 3 or 4 weeks In some seasons a different mode o f practice is better. I have known seasons in which cath. & diaph. were the best treatment Although for the first 15 years of my practice I considered nothing more unfortunate than to find the child under the operation of a cathartic. In these cases, it was the form in which the duodenum is also affected in a similar manner Case Wallingford [emet.] failed & cal. & diaph [illegible] Others that season occurred which required the same treatment Bronchotomy has been recommended I have seen it performed but never with success It has sometimes succeeded But in the cases which I saw the membrane form lower down, and the patient die 186 You will see by looking into the throat the tonsils perhaps red & the epiglottis certainly inflamed 187 Angina Laryngia Another form of the croup has been called angina laryngia [illegible] the croup you can see nothing by looking into the throat In this the epiglottis & the [illegible] glottidis are affected From the larynx being affected, the actions & more spasmodic Frequently comes on while eating Case of my child While apparently well was taken while eating with the peculiar croup & respiration of croup & became alarmed & treated This is the form which attacks old people probably Geo. Wash. died of it Case The first time I saw this disease the pat. had had pneumonia & may nearly recover when he went into the cold open air without stockings. I was informed that he was taken with difficult respir. & without seeing him prescribed seneka injurious ultimately refused to swallow anything as the act brought on a spasm I tried bleeding, blisters, vapour & after awhile persuaded him to swallow when I gave him 4 gr. tart. ant. in a cable spoonful of water 188 Angina Laryngea The dis. is brought on by eating And if you examine the throat you will see a redness perhaps upon the tonsils, and will certainly see the epiglottis inflamed Bronchotomy promises more in this form of croup Readily distinguished for the other by difficult deglutition paroxysms being brought on by an attempt to swallow This firm It is not of much consequence to distinguish the forms except that laryngea is more rapid And you must avoid acrids in this form as they irritate the fauces & produce spasmodic action For the spasmodic symptoms give in the latter stages of it asafoetida which also acts upon the secretion tinct. ant. & opium It must be remembered that this disease cannot be cured by bleeding alone. It is too far out of the circulation. But by reducing the system very 189 Croup concluded When croup follows other diseases it is more rapid and dangerous they are very apt to die particularly when following ulcerated sore throat You may treat by emetics blisters metallic emetics etc. but you have not so much strength left in the system to act upon In the latter stage where we wish to throw up the membrane the stomach may lose its excitability to a particular emetic then you are to change the em. I have succeeded in throwing up Upon dissection a membrane is found formed But sometimes it is wanting and in A laryngea then probably is not [time] for a membrane to form Vide p. 211 low and suspending the functions you may change the secretions perhaps 190 191 Scarlet Fever Withering in his first edition separated ulcerated sore throat from scarlet fever. In the second he changed his opinion Where there is much heat and fullness of the pulse I would much prefer a strong dose of cal. followed by antimonials [to] commencing with emetics Or is Dr Rush & the elder DR Barton thought best turpeth mineral Epispastics are to be used with caution & adopted this rule viz to apply them where there is much tumefaction [illegible] & enlargement approaching the quinsy. Scarlet fever after resembling quinsy and is with difficulty distinguished except from the previous affections of the family and neighborhood Mineral acids have been considered specifics Chlorine was much used in this town in [1801] etc. as a fumigator. You may give it internally with advantage A great variety of gargles are used generally stimulating ones are better as those of capsicum (with salt say in cider water) In some cases capsicum does not do well If the patient is too weak to gargle use a syringe 192 Scarlet Fever Chlorate of potash was used with advantage to quiet the stomach. It allayed irritation etc. Ammonia and amm. with camphor & gum arabic In the progress of the disease mineral emetics, as sulphate zinc will be useful to excite the system acting speedily they do not exhaust sul. zinc 5 to 20 grs mosely’s solution was the form most used Sulph. copper 2 to 5 gr. also as an emetic Acetate of copper was formerly kept as a nostrum in some families ½ to 1 t. sp. of sat. sol. of common verdigris 2 to 3 gr. In some cases and seasons cath. are required. I have treated children without a single cath & yet in the same family I have given ant. followed by cal. & worked off by salts and senna If a diarrhoea occurs early it must be attended to white decoction 193 Scarlet Fever Dr With. lays great [illegible] upon diuretics particularly senega giving it throughout the disease. In moderate fevers diuretics eliminate morbid action will Serpentaria may be given freely throughout the disease adding bark alcohol ether or wine Diuretics & diaphoretics Irritable state of the stomach is to be counteracted by irritants by aromatics white decoction etc. etc. a little alcohol upon the fauces voiding a great bulk of liquid Case of a boy in delirium his father was forcing down articles which he was puking up I put into his mouth spoon dipped in brandy 20 or 30 drops his eyes opened immediately said it was good continued it in tspfl doses through the night saved his life Scarlet fever occasionally passed by insensible gradations into quinsy and is of an inflammatory character. No one character will distinguish them No one mode of practice will answer in all cases though if any indiscriminate mode of practice is to be followed that by emetics and stimulants will be best In many cases no evacuations at all are to be used if this you must judge by the symptoms In the same family I have lately treated one or two patients with antimonial and nitre and another who had been worn down by fatigue and watching with feeble pulses vomiting coldness etc. was treated by external heat, brandy in moderate 194 Scarlet Fever quantities, counterirritants spiced tea etc. to stop the vomiting # (One of the best articles in fevers of a low grade is spiced tea or hot spiced wine or brandy. The strength is apt to give out first, and an excitement kept up in the mucous membrane of the stomach will have a beneficial effect) # The first patients in this family I had evacuated freely both by vom. & purging etc. while this patient had no evacuation goodness & was supported throughout the whole progress of the disease After I had seen the disease in 3 or 4 epidemics I thought I had seen the disease in all its forms but I found oftenwards that I met with different forms still Not only different epidemics differ, but different cases during the same epidemic may require widely different treatment In the malignant epidemic of ’94 I was informed by some physicians that they met with cases in which there was increased action though the many cases of the epidemic ran rapidly in the [illegible] gangrenous state In 1803 we generally gave emetics It is said that in the malignant form the eruption is a bad symptom. I do not think so. I think it better for a general eruption to come out the action is less unequal than if a scanty or no eruption appears I hesitated in 1803 much about the application of blisters & I finally found that the rule was a safe and beneficial one to apply them where there was swelling of the tonsils In this epidemic I gave bark, the mineral acids, alcohol, wine, and (for the first time) tinct. canth Tinct. cant. [illegible] zi to pt. give 20 gtts once in 2 hours ½ as much to a child 195 In many cases [illegible] requires to be qualified & corrected by serpentaria or carb. amm. If wine injures the stomach and [illegible] too locally continue carb. amm. which will render it diffusible with white vinegar will have somewhat of an effervescing mixture Use also effervescing mixtures, as soda water, with brandy or ether, or aromatics tincture. It is no objection that you thus combine stimulants and refrigerants, for you thus get diffusible action and obviate unequal excitement. The min. acids may be given in form of punch The sugar will be grateful & useful A diarrhoea is apt to take place in the commencement of the disease. Use white decoction laudanum & injections of starch & laudanum RX starch 3 bal. sp. SS. 30 gtts to 2 t.sp. Pay great attention to cleanliness of the patient Where there is fainting apply ammonia and ether & spirits at the nostrils keep them applied to the nostrils to prevent fainting, I have never known any injury done by over excitement by these articles thus applied Capsicum is used in tropical [illegible] in very strong decoction. Salts and vinegar has been much used as an antiseptic gargle? For the diarrhoea use tonics, bark, contrayerva has been though valuable. Avoid injuring the stomach by distention 196 A variety of garbles (or injections by a small syringe) are used. [illegible] rosemary has been thought a specific & carried hundreds of miles into the country Use others when pat. is disgusted with one # Sulph. cop. ac. cop. nit. sil. ([touched]) apply these with a swab What is called the leathery inflammation is sometimes met with. in which the skin dies at first and afterwards comes off & then a discharge follows. This affection sometimes extends down the throat. In such cases apply blisters to the sternum Touch the part with nit. sil. in such cases. IN one of these the blister on the sternum produced an ulcer which was 3 mo. in healing and in another though the affection with throat was relieved the ulcer for the blister destroyed the little patient # [illegible] oak bark etc. pomegranate combine brandy aromatics etc. It might to be remembered that in the latter stages of ulcerated sore throat where there is an accumulation of [many] a phagedenic ulcer, emetics of sulph. zinc give tone and excite action also when Acetate copper in the latter stages used in an emetic as a tonic or locally applied as a caustic When the stomach fails in the latter stages we give capsicum in pill or strong infusion (2 tab. sp. to the pt makes a strong infusion give to an adult a tablespoonful also acrid oils There seems to be an erythematic infl. of the mucous 197 membrane of the stomach hence acrids are indicated to excite action Bark jacket also it seems to have some effect In the latter stages also a cath. will frequently be beneficial an accumulation of feces may exist given mild cath. as castor oil or perhaps a dose of cal. an emetic also may be needed One thing to be guarded against in young children is the supervention of dropsy In 1803 I had 3 cases all the writers considered the disease as one of weak [illegible] action and requiring tonics bark etc. Not successful Bark does not generally do well when there is unequal action I have known in such cases the brain & nervous system apparently much affected I have given in such cases digitalis and cantharides to produce as new excitement and ally this irritation in the nervous system Case related patient very low from a disease digitalis was given and elaterium being advised was given when the patient died upon the second evacuation In general treat these cases with diuretics a moderate use of cath. narcotics & remedies etc. Digitalis is the best narcotic but be cautious giving it to children In ordinary cases of such dropsy a cath. will remove it and frictions & exercise in the open air. Various articles are popular as ol. [mor] [199] [illegible] ol. gaultheria various irritants etc. and to encourage the attendants to persevere in rubbing you may suffer friction to be made with these mere dry friction though probably just as good does not seem to them like giving medicine Various astringents may be 200 Hydrocephalus The management of the pat. is equally important with the medication avoiding in proper diet alternatives of temperature, and all debilitating irritating and exciting agents all the exciting causes of disaster. Sometimes a patient may (after a fall perhaps) continue one two or 3 years not entirely [illegible] and yet not quite sick and finally die of eff. of the brain Sometimes in strumous habits canth. internally may be advantageous Blisters translate action The applications of remedies to the Schneiderian has been thoroughly treated by Dr Malachi [Foot] in the N.Y. Rep. about 20 years ago. The subject has not bee sufficiently attended to Give in the way turpenth wine (mixed with liquorice) verat. vir. apreyn. [illegible] myrica cerifera etc. If a discharge can be excited relief is afforded Salivation can rarely be produced in children In some cases where there is paralysis the acrids and some of the narcotics as strychnos Blisters are applied by some to extreme parts of the body I sometimes change the place of the blister to the back of the neck etc. But the back of 201 ears is more efficacious. It seems to have a grater affect upon the constitution to excite a discharge from this part If the symptoms indicate bleeding bleed leech also. If there is much infl. about the mouth scarify the gums as a depleting measure “In grade of action the fever of hydroceph may vary from high entonic inflammation or phrenitis to low strumous fever. If the action is too high or too low counterirritation will fall in with the morbid action We must first bring it to the “blistering point” (Rush) “Blisters to the head are thought by some to be dangerous and the ears or neck preferred” “In irritable cases and scrofulous habits, strong cathartics are hurtful. Give blue pill especially when the bowels are primarily affected. But in entonic phrenetic fever, use the drastic cath. & tart. ant. ut supra after depletion” “Scrophulous predisposed mesenteria glands generally affected the fever analogous to hectic never entonic pulse soft, frequent, quick I have tinct. cantharides with advantage in this variety” [204] Volvulus continued from p. 89:a:1/2 “Cases I was called to a child 2 years old which had symptoms of irritation and was obstinately constipated It had been carried on the belly upon the shoulders of another person Gave a cathartic Ordered an injection but the attendant said it would not [illegible] The cathartic was thrown up patient died Upon examination after death no color could be found. In the upper [illegible] rectum there was a tumor which seemed of solid flesh as large as the doubled fist inflamed. The color had been completely removed from its place” “I was called to another family where the children had died when 5 or 6 months old as was supposed of an affection of the brain. This child appeared well when born but was very costive etc. Upon p.m. [illegible] 2 inches of the small intestine were found contracted to the size of a goose quill the coats were thickened & the course the cavity must have been extremely small This contraction undoubtedly existed at birth. This contracted part was received into the part below it, and no [illegible] could have availed” from p. 99 ½ “In another family they had lost all their children at about such an age. They supposed the disease to be hydrocephalus. The older physicians called it so. I told them I could not tell what the disease was but it was not hydrocephalus I had then seen no case of volvulus. There were strong 205 marks of irritation the face was pale and much distress was depicted with countenance the head was rolled back and hands tossed violently. There was vomiting and tenesmus and a discharge of mucus streaked with blood Cathartics had been given under the impression that the disease was an affection of the head The cathartics aggravated the disease which ran a rapid course and the child died. The small intestine was found received into itself and its cavity obliterated. This obliteration of the cavity would not of itself cause death; for a patient may continue several days with perfect torpor of the bowel. It is the irritation as in cholera morbus which is the immediate cause of death which [illegible] death usually occurs within 24 or 36 hours” “Called to a child one year old constant vomiting stool, mucus streaked with blood Directed mucilaginous injections & fomentations combined with opium Gave opium freely internally 10-15 minims to allay vomiting. The symptoms subsided gradually & in 3 or 4 days the feces passed off without any cathartic” “Was called to an Academical student had given cathartics and they did no good. Called in older physicians. They were in doubt respecting the case and advised not to do any thing as we might do hurt. As I was sitting by his side I heard a motion in his bowels. I noticed that it passed down to a certain point and then stopped. Upon examination I could distinctly feel the involution. I tried injections and some [illegible] of them would stay. Ordered a spermacetic candle with opium upon its extremity to be passed up the rectum and allowed to remain. It was s 206 passed in to the length of 10 inches. The opium allayed irritation and the application by repetition replaced the part & the patient recovered another case cured by a bougie” “Opium by taking off the spasm and restoring the natural function of the bowels may be said to act as a cathartic just as in spasmodic colic” From p. 56 “I have given when I could obtain it, the [resin] of Mandrake podophyllum peltatum It operates kindly, and more certainly than any other article. If the western gentlemen who have so much mandrake and whiskey, would furnish a supply. I think it [will] supersede every other article” “If there is torpor & a stuffing or infarction of the bowels we must use injections to assist cathartics repeating them every 2 or 3 hours. If other cathartics do not operate give castor oil which will promote their operation” “The particular kind of injection is not important and may be left to parents Thoroughwort, camomile, mayweed catnip, dandelion, weak soap suds salt & water a tablespoonful to ½ pint water 207 Continued from p. 57 “The stools resemble meconium. In the progress of the disease they exhibit small pieces of a membrane of a dark green colours, about the size of the petals of peach blossoms floating in a dark green fluid. The membrane of coagulable lymph, resembles that formed in angina trachealis and sometimes as in that disease it is formed in such quantities as to cause obstructions Still in this case it may not destroy life the action of this part not being so immediately essential to life. Stools of this kind sometimes attend the bilious colic of adults. They are an indication that farther evacuation is needed Continue the calomel or combine it with magnesia or soluble tartar, or phosphate of soda or other neutral salts 208 Infantile remittent continued from p. 60 “Cases A child had violent fever gave calomel & cathartics warm bath symptoms abated. In 2 or 3 weeks the regular symptoms of hydrocephalus appeared; & the patient seised in the greatest danger. In a short time these symptoms were relieved by a violent and dangerous attack of thrush The patient was very much exhausted lay several days very low gradually emerged and after a long course recovered. “Case of a small little boy 5 or 6 years of age After 5 or 6 days head affected & became maniacal very irritable and cross swore profanely would bite and strike all who came near him. If any thing was attempted to be administered he would shut his mouth. If his mouth was pried open he would close his throat with his tongue Advised his parents not to trouble him nor notice him to pass by him with drink roasted apples etc. but not to offer him any thing. The first day to he took nothing second day took roasted apples etc. readily but ate too much mania returned, but soon went off & patient recovered” “In one case the pat. took nothing for a length of time. Recovered by use of [even ato] & external applications as aloetic plaisters to the bowels etc.” Scrofula continued from p. 163. “Scrofulous swellings are very difficult to excite to suppuration I have however then poulticed without effect for 2 or 4 months Of late I have disused poultices & have applied blisters as soon as may be to excite invigorate the absorbents and act as discutients. They do not disturb the system. If there is suppuration the relaxed state requires stimulating applications lunar caustic vegetable astringents etc.” “Case of a young act 18 with bad cough swelled neck scrofulous temperament Gave laxatives blue pill afterwards rub & spec. Then gave decoction of [cistus] [canadensis] for several weeks and pat. recovered “ A physician (Smith) on Long Island (from an old recipe) has acquired reputation by the use of cistus canadensis combined with uva ursi at the same time enjoining a strict & spare diet as in dyspepsia” “I have given with cist. canat. 1/8 gr. corr. sub. & also decoct. scroph. maril. which is thought by the vulgar to be a specific It has been sold as a nostrum to facilitate parturition called nerve root.) I think it useful in scrofula” “I have known the comptonia [illegible] folia given internally. It is tonic & has balsamic rpoperties” “The remedies particularly indicated are tonics & deobstruents such as will not produce congestion such as uva ursi cistus scrophuloria contrayerva agrimonia (entire plant or root angostura etc.” Sea bathing is recommended, but if the lungs are affected, it will not be advantageous. A sea voyage to the eastward has been of service the constant motion of the vessel stimulating all the vital organs to healthy action The change of air is beneficial & at a distance from the shore there is no danger of taking cold In chronic complaints attended with a want of vital energy I direct a voyage to the east rather than to the south Croup continued from p. 189 “Vapour bath Inhalation of warm water in a [pour] blow a current of air through hot water upon the pate & by means of a coffee pot with two spouts” “Tobacco or snuff applied to the patient” “Croup is an epidemic disease & of course it will vary at the different periods of its appearance We must take into account the prevailing diathesis I have described the disease as it has usually occurred in my practice” “The proxim. cause of the dis. is a peculiar morbid action translated to the traches for the disease arises from general causes acting on the system. In catarrh diseased action is seated primarily with mucous membrane. The exciting causes of croup act on the surface and with different diathesis the same crises might produce pneumonia, dysentery enteritis or cephalitis “Disease determines to the weaker part as the rod attracts lightning” Rush Water & snow cold damp air a [illegible] & low situation sudden changes as when the wind blows from Canada or the gulf stream are the exciting causes “In the treatment sanguinaria, if given early in strong decoction very freely, so that enough of it shall be given & still it vomits or relieves the symptoms, in very efficient practice adopted by Drs Jared Potter & Kirtland “But if inflammation has taken place & the second stage has arrived seneca and sanguinaria are both too stimulating and I have seen them do hurt sanguinaria is less stimulating than seneka For p. 137 “Some authors state that the disease is entirely inflammatory not regarding the forming stage. If the forming stage is wanting we must rely solely on the antiphlogistic treatment” “This disease has a direct tender eye to death The physician must take it out of the hands of nature” “When croup supervenes upon catarrh as it frequently does of late year the mucous secretion and expectoration usually cease suddenly “When croup follows diseases that prostrate the system powerfully as angina maligna, there is little chance for recovery. The sympathies of the system are broken down and Archimedes can find no fulcrum for his lever” “I used tart. ant. at the commencement of my practice and succeeded with it as well as I could wish I therefore contained it, but only in the early stages & to produce a powerful orgasm. If it acts upon the stomach only it aggravates the disease Other practitioners rely upon different articles & probably with equal success bearing in mind however that a powerful impression must be made Decoct. sang. to prostration & vomiting seneca or lobelia inflam with the same view” “Sulph. copper & zinc & acetate copper useful to assist in the latter stages or when other emetics are worn our. So also hives syrup which is much used at the south.” “For six or 8 years past croup has been occasionally different from the pure inflammatory. It affects the lungs and duodenum& calomel and cathartics are the remedies to overcome this form. The cough is more frequent and loose the paroxysms less distinct there is pain in the epigastrium vomiting & a membrane is formed in the duodenum which passes off. I have called it angina duodenitis. The same year ulcerated sore throat came on with it the slough leathery & like a burn it seems to be intermediate between A. tonsillaris & A. maligna The application of lunar caustic by a pencil or brush would prevent croup Blisters to the throat & chin were useful yet a blister would produce the same action as existed in the throat, forming an ulcer very difficult to heal Slough ¼ in. deep 3 mo. in healing. In one case the blister cured the croup and the ulcer killed the patient It is desirable to translate action to parts less essential to life. Cal. & carth. would translate it to the duodenum Emetics & powerful treatment do hurt here. The vapour bark is good. “Croup sometimes recurs several nights in succession A. Laryngea is more apt to do so” “When crop assumes a chronic form emetics irritate inhalation of vapour blisters opium diaphoretics & expectorants” “In chronic croup the inflammation in erythematic and not membranific. The vapour bark often does wonders Tartrate of sanguinaria in ¼ gr. doses Tinct. hyoscyamus gtts x N.B. Dr Woodwd treat of subacute ([S?bertonic]) & typhoid croup the latter contraindicating tart. em. & requiring sanguin. turp. mer. calom. etc. & sometimes capsicum, ammonia & even perhaps wine & alcohol. “One of the most extraordinary examples on record however of the effect of disease in developing of perceiving a certain class of relations is that of [Zerab] Colburn His history is well known When quite a child in his sixth year, without any previous instruction, he could by mere intuition perceive the relations of numbers with so much readiness and precision, as to solve almost without reflection questions in arithmetic which would require a long calculation to enable others to answer. How he obtained this result he could not tell. The answer seemed to present itself to his mind with the same readiness and conviction of its truth, that the proposition tow and two make four does to us. These facts I saw are well known, but it is not so well known, that this power was the effect of disease. That such was the case I have very little doubt This was the opinion of a very distinguished physician who saw him at the time, and who ascertained that he was then affected with a peculiar nervous disease the same (chorea) which Jane had a few years since. In conversing with Mr Colburn about a year ago I asked him if he retained the power of calculation which he possessed in his childhood. He said no, and attributed the loss to the want of its exercise. But why should exercise sustain a faculty in existence which was spontaneously developed?” “Account of Jane C. Rider the Springfield somnambulist; by S W Belden MD. Springfield 1834” p. 108 “The discovery of Zerah’s power of calculation was purely accidental Zerah not having yet completed his sixth year was overheard by his father, as he repeated to himself in his play, parts of the multiplication table. The father surprised proceeded to examine him & [found] etc. 1 Diseases of children [B illegible 31] Proposed plan name – history symptoms & causes [Regar] plan of treatment minutely described Other modes of treatment Miscellaneous remedies N.B. Collect all his remarks on art of practising medicine Contents page Introduction Tumour of the head from difficult parturition 5 Cutting the frenum linguae 5 Congenital hydrocele 5 Management of children – as to Particular appetites – Preventive medicine 5 General nature of the diseases of children 6 General operation of remedies in children Diseases within the month Retention of the meconium 8 Jaundice 11 Acidity, Flatulence, Hiccough etc. 12 mothers milk & cows milk 12 Costiveness & its consequences 12:a Vomiting 12:d Diarrhoea 12:f Prolapsus ani 12:l. Aphthae 13 Eruptions in general 19 Strophilus interlinctus or Red gum 19 Strophilus candidus 21 Crusta Sactea 22 Eruptions of Dentition 24 Eruption resembling the itch 24 Venereal Eruptions 25 Infantile Erysipelas (Rose rash) 27 Sore ears (Intertrigo) 30 Tinea capitis [???phlicus]- [illegible] [illegible] on [illegible] [1821-2] 32 Dentition 34 Cholera Infantum 40 Infantile Remittent 55 Mesenteric Fever 61 Tympanitis 66 Worms 69 Volvulus 86 Nervous Rheumatism Infantile [remedy] 89:a. Convulsions 90 Epilepsy 96 Catalepsy 99 Chorea 100 Ulcerated mouth 103:a. Gangrene of the mouth 104 Parotitis or mumps 112 Tonsillitis or Quinsy 115 Rosalia or Scarlet fever 120 Croup or Bronchitis 132 Laryngitis 139 Epidemic catarrh resembling croup 141 Whooping cough or Pertussis 144 Rickets 158 Scrofula 162 Mesenteric fever Hydrocephalus 164 Chilblains 176 Painful aff. from cold without discoloration 177 Burns 177 The cause either is to be found in [???uctural] [illegible] for the [illegible] This will [illegible] men to trust their lives to unknown men, or to fictitious names in the newspapers, where they would not trust property even to a small amount # Formerly prescription of an experienced physician very often set aside for that of the nurse or a negro woman 1 Diseases of children 1 In this part of our course I direct your attention to the history of man in relation to his habits, diseases, & their remedies in his infant state That this subject has occupied the attention of the learned less than any other branch of the medical profession, is universally acknowledged 2 – It is unnecessary for me to enforce the importance of the subject, by any remarks which might be made concerning the evil to society from a neglect of a part of the practice in which the community is so deeply interested 3 – I need but advert to the evils which must result from the practice of committing the management of the diseases of infants to a class in society which is the lowest in point of intelligence 6* [the opinion of the nurse is sometimes taken in opposition to that of the physician – On this subject the world seems to desert its principles of reasoning on other subjects. If a point of law is to be decided men will not trust to a petty of the court, in preference to that of an experienced If a text of scripture is to be explained, men apply to a learned divine in preference to the mere servant of the church & on the subject of wearing apparel it prefers the opinion of the master to that of the apprentice.] 4 – That this subject has occupied the attention of the learned less than any other branch of our profession is universally acknowledged. (The French & Germans however, have neglected it less than the English; and the American physicians have been in the habit of paying more attention to diseases of children than the Europeans) 8 Great attention has been paid to diseases of children within the last 30 or 40 years It has been most neglected in Europe, but less by the French & Germans than by the English 17 European practice differs from ours – but less so at present than formerly because the constitution of our countrymen are coming to resemble those of Europeans 12 It is also the case that European diseases differ from ours on account Disease, here is [illegible] more violent owing probably to the greater of climate etc. Angina [Trachealis] is much milder with them & requires much milder treatment # vicissitudes of the weather 2 5 - The causes which have excluded physicians from the treatment of [infantile] diseases infants, having ceased to exist the subject is now receiving the attention which its importance demands 6 – These causes may be enumerated in few words – viz. the exclusion of the faculty from the practice of midwifery – from the difficulty of obtaining correct ideas upon the subject from its obscurity – the prejudices of the public on this subject – attributing as they do intuitive skill to nurses and matrons * vid. page [illegible] & perhaps also the indifference of the profession 7 – At the present period, however, the enlightened physician watches the mother during the whole period of gestation, receives the child upon its first introduction to the light, & prescribes for its diseases from infancy to old age 9 – As knowledge however must on this subject, as on every other, be progressive, it follows that this part of the profession having but recently received the attention of physicians, has not attained the perfection of the other branches 10 – American physicians need American treatises on this as on other medical subjectds 13 – European practice, as exhibited in their works, is too slow and mild to meet and overcome the morbid excitement of acute diseases in our climate. [Chronic diseases may be treated They practice no deceit 3 with mild remedies, but acute diseases are made worse by remedies if those remedies are not sufficient to overcome the disease The action of the remedy falls in with the diseased action and aggravates all the symptoms if it is not powerful enough to overcome the diseased action IN such cases disease is to be taken out of the hands of nature. The powerful [enemy] is not to be irritated unless there is a prospect of overcoming him] 14 – The difficulty of acquiring a knowledge of the seat of the diseases of children, on account of their being unable to communicate their sensations by language, has been made an excuse by some physicians for neglecting the subject of infantile diseases We may remark however that the difficulty of attaining a correct knowledge of a subject, cannot be given as a reason why it should not be committed to men of intellect & science 15 – Though children cannot communicate their sensations by language, yet the other symptoms by which we determine the seat of their diseases are more uniform in their appearance & more certain in their indications than those of adults 16 Children are under no restraint from feeling fear, [delicacy] or from false modesty In the infant, the mind does not react upon the stomach & destroy its function When Dr Harris published his essay on the acute diseases of children Sydenham said to him “you are the first man I ever envied and it is my firm belief that your little book will be more useful to mankind than # Adult patients also will often deny the existence of dangerous symptoms; for fear they shall be considered as very sick The subject has not yet been thoroughly investigated. No regular course on it has been [illegible] until quite recently in [illegible] of the European schools. I recollect the embarrassment under which I laboured under at the commencement of my practice Cases frequently occurred which were not described in any of the books [&] I was obliged to acquire all my knowledge on the subject from older physicians or from experience. My students have often expressed to me the satisfaction they experience from an examination of my notes and they have often quieted the anxieties of parents by reading extracts from them # In my embarrassment upon being first called to a sick child though familiar with the treatment of adults & having attended the first schools in the country I found my information & in books as to [illegible] nature or treatment and was obliged to have recourse to the older physicians 29 [Dewers] is popular addressed to mothers, very prolix & not intended for a text book but perhaps able [work] & is the 30 [illegible] # Parents think a young physician will do well enough for a young children and are much more apt to call one in for such patients 4 mind does not react upon the stomach & destroy its function We are at no loss how much to attribute to disease & how much to [illegible] # 17 – Still with all these advantages & notwithstanding the importance of the subject it has been neglected & has received less attention than any other branch 18 – When Dr Harris published his essay on the acute diseases of children Sydenham said to him, you are the first man I ever envied, and it is my firm belief that your little book will be more useful to mankind all I have written” This opinion was not founded upon the merits of the book but upon the fact that the attention of physicians would be drawn to this part of their profession, not the least useful though the most neglected 25 Authors on this subject & their merits 26 Underwood Still the department has received less attention than any other branches of our profession 27 Dr Rush in his works, has many remarks 28 Periodicals contain more or less upon the subject 21 – No courses in any of the schools 19 – Some physicians of the first respectability have acknowledged their ignorance & given up to nurses 20 – I recollect the embarrassment I suffered upon this subject # It is a common complaint 22 Since I have lectured upon this subject, our students at parting have expressed their satisfaction. 23 Young physicians are first called to children because the older ones neglect them # hence its importance to them 24 Parents however seem, as a matter of fact, to prefer a young physician, for a young patient! # 34 – I shall first remark upon a few surgical cases which occur to the young physician soon after the birth of the child [illegible] cutting the frenum. I have never seen a case in which this operation was necessary. It is very common for nurses to insist that children are tongue tied. Dr [Eneas Munser] was called in such circumstances he remonstrated the nurse was instant until finally he drew the back of a knife across the frenum & the child he told [illegible] [illegible] hurting and this with this [result] was relieved to the great satisfaction of the nurse. If there is a false frenum it may be divided.” this [illegible] [frenum] is never so short as to confine the tongue & cutting it is a dangerous operation # They will tell you that this particular appetite is indicated by the natural crying of the child The mother will set herself to recollect some former longing of her own [illegible] 6 Hydrocele Young physicians are often called on to prescribe for congenital hydrocele in young children The complaint is apt to excite alarm but neither troublesome nor dangerous. It is readily distinguished from [illegible] by its transparency, insensibility, & not yielding to pressure. In the course of my practice I have had to operate in but one case in children. Dr [Dewers] recommends pouring considerable quantities of cold water on the part. I myself have frequently cured it by washing the part with cold water in the morning and applying camphorated spts in the course of the day. You [illegible] direct the application of spirt & water, camphorated spirits, [muria??] of ammonia, [opium], spirits of nitre, in short every discutient Or you may direct astringent lotion, as a strong decoction of maple bark, spriaea Fomentosa Geranum, Rhei etc. Case in which I had to operate year old probably neglected 2 or 3 inches long about as large as a small egg. Operate without a cannula - with a lancet & catheter & injecting syringe – water 1/6 or 1/8 port wine – children more irritable - vomiting 5 Tumor on the head 35 Children are sometimes born with a tumour on the head occasioned by difficult labour This may be distinguished from a tumor caused by a deficiency in the bones of the cranium, by a uniform hardness. “We may apply mur. amm. or spt & water” 36 – Cutting the Frenum 37. Hydrocele 31 Management Appetites 32 A prejudice prevails in some classes of society with respect to a point in the management of children Some children are thought to be born with a strong appetite for some particular kind of food, which was possessed by the mother previous to the birth of the child & inherited from her. It is thought that the child will [pine] & ultimately die, if this [illegible] appetite be not gratified # It is probable that a belief in this doctrine has caused many children to be killed by the administration of improper food A fact of this kind occurred in Humphreysville, which nearly proved fatal to the child. Vide next page Preventive medicine 33 As a general rule medicine is not to be given to children in health for fear they should be sick. Some are nursed to death, while some die for want of nursing. Some are fed to death while others are starved Some are physicked to death while others die for want of medication injection immediately with [draw] healed [illegible] with swelling The child cried much # - a council of females was called who set themselves to make out what the child needed Finally the mince pie was concluded to be the article the child sucked down the inside & the report was that this effected a cure & saved the life of the infant. Prof. I inquired of the attending physician who informed him that the child was indeed alive and well at present but that it was made very 8ll by the mince pie & came near losing its life. The crying of the child in this case was probably nothing more than a trifling increase of the ordinary crying of very young infants, which is a natural and wholesome exercise # The al. can is large in proportion to the [illegible] of the whole system # The above is a good example of the various prejudices which have prevailed among [nurses] respecting the management of children. Owing to the influence of enlightened physicians these are no disappearing. (examples to be given) 6 38 – Diseases requiring medical treatment General considerations 39 – In investigating the causes and seat of the diseases in infants the mucous membranes claim particular attention 40 The action of this membrane is greater in the infant than in the adult constitution Its secretions are often morbidly increased & are sometimes diminished. It is subject to spasmodic action and to inflammation [illegible] with [illegible] or decomposed with effusion of coagulable lymph. “It is subject to turpidity & to spasmodic action which by sympathy extend to the whole system 41 The liver is much larger in proportion to the body the infants than in adults “& its secretions are much of [illegible] as to quality & quantity than in adults” 42 The secretions are much concerned in their diseases. They are changed as to quantity and quality # Prescott child no ducts lived 3 or 4 months and was excessively emaciated – there was no bile in the stools There was no [previous] duct for the gall bladder into the disorder # There is greater susceptibility to action & tendency to conversion # Just as emetics are given to a stomach [complaint] from excessive quantity of food 7 42 The nervous system of infants is more easily excited, and more affected by the various causes of irritation such as dentition worms acrid substances in the first primae via passages etc. 43 – The blood vessels are more rarely the seat o f disease in infants than in adults – particularly, primarily so much as irritative [acid] if they were affected the action is not [illegible] 44 – Consequently their fevers are fevers of irritation, rarely enteric or those of inflammation 45 Operation of medicines Children bear evacuation better than adults witness the long continued diarrhoea without much debility following, or the salivation for mouths during dentition without a waste of vital energy In operating upon the abdominal viscera it should be [illegible] it is not for the purpose of mere evacuation, it is to produce an excitement for the purpose of overcoming a morbid excitement also to produce healthy excitement a case of torpor # The milder purgatives should be used, the drastic being irritative. Emetics Bleeding Do not bear narcotics vide p. 11 2 – In general the evacuation of the meconium should be effected by the [colostrium] or first milk of the mother which has a laxative property # The child should be put to the breast within 2 or 3 hours from birth # unless [illegible] Instead of suffering the nurse to feed the child for the first 2 or 3 days the breast should soon be presented for if the child feeds it is in danger of losing the instinct to suck If the [colostrium] does not bring away the meconium we may begin with soda as mentioned below or with cold sweetened water Some give a little cold water at first vide [infra] 5 – In strong children cold bathing may be employed with advantage, but the bath should be made tepid for weak ones & gradually used colder as the child can bear it # “If from the exhaustion of parturition the mother be unable to suckle let the nurse commence feeding at the end of 3 hours” vide infra Give a grain of carborate of soda in a teaspoonful of water until iii qts [have] given # The meconium is frequently evacuated during parturition. After birth also the al. canal is set in notion by the crying and mother of the child and the stimulus of the air upon it vide p. 10 skin. # Colostrium is of a yellowish colour probably contains bile & is cathartic # It was formerly supposed that the child should not suck at first. The consequence often was that the child lost the interest to suck 8 Retention of Meconium 1 – The first diseases of infants which claim the attention of the physician are those which arise from retention of the meconium. The meconium is a matter always existing in the bowels at birth & having a dark green colour when evacuated. It resembles tea but is more mucilaginous # It will ordinarily be sufficient to give a little molasses and water to the child until it receives the [illegible] or first milk from the mother which has a laxative quality 6 – If it is suffered to remain a train of diseases may follow. In the diseases which occur within the first moth after birth the retention of the meconium is always to be suspected as the cause 7 – The diseases caused by retention of the meconium are Severe paroxysms of pain in the bowels indicated by crying & writhing – Tumefaction of the bowels. Convulsions. Epileptic fits. Trismus nascertium or Locked Jaw This last disease is very common in some of the West Indian islands, but I have never seen it in this place 8 – Whatever disease may arise from retention of the meconium the principal indication will be to remove the irritation by evacuating the bowels. This is effected by cathartics. A teaspoonful of castor oil is generally sufficient. If [illegible] necessary 1st indic to remove meconium 2nd obviate effects # IT will be sufficient to pour on boiling water instead of boiling the materials in the water The strength however is of little consequence Sometimes the most powerful remedies are to be used beginning with mild. These used full doses of calomel, scammony 2 to 4 yrs – [illegible] assisted by injection, & warm bath until the bowels were moved Wait how long for the operation of each? # By emollient injection, irritation is allayed, and if the lower part of the bowels is excited the rest will be Dose 2 to 6 pills each pill containing 1 gr. of (calomel) # Chalk & calomel is a substitute for blue pill – perhaps the chalk qualifies the cal & at least it corrects acidity Antimony should scarcely ever given to children within the mouth # A great part of the calomel has no effect [illegible] it does not come in contact with the coats covered with mucus In cases where there was great quantities of [mucus] I have given full doses of cal. 9 the dose may be repeated every 4th or 5 hours until half an ounce has been given 8 – If the oil is rejected from the stomach Senna & Manna may be given – zi of the former to zss of the latter boiled in gill of water # & administered freely until the bowels are moved once in ¼ or ½ hour “ Rx Sennae zi [illegible] ferv. 1 gill 1 or 2 teaspf every ½ hour” 9 – The operation of the cathartic should be assisted by emollient injection # 10 – Fomentations to the bowels will assist the operation of cathartics & if spasms exist, will always be needed for their relief 11 Cathartics of various kinds 12 The best cathartic which I have used for infants within the first month after birth is the blue pill (or [mellated] pill It rarely offends the stomach and never produces griping By it the action of the liver & the secretions from the mucous membrane of the intestines are excited more than by any other cathartic except perhaps calomel. In my practice I have never known an infant salivated by it. # 13 In severe cases where the blue pill is insufficient we must have recourse to calomel, which may be given in doses of from two to 10 grains. It is often necessary to give as large doses of calomel to children as to adults owing to the great quantity of mucus in the intestines by which they are defended from its action. # The meconium scammony or jalap as a laxative & had them operate mildly If the cots were [naked] [illegible] a dose would prove fatal for irritation # This is a mild cathartic and supposed to act chemically. # “Evaporate the [illegible] over the fire stirring it until thick then add chalk till it is of a consistence suitable for pilling Each pill may contain 1 or 2 gr. of Dose from 2 to 5 gr. Or it may be dissolved in herb Fish, gall has been recommended [illegible] gall Rattlesnake has been thought to have specific properties especially in fevers. This article is bitter, tonic [illegible], laxative, & [illegible] Continued from page 8 “The infant may be put to the breast in one or tow hours from birth This course will produce permanent contraction of the [uterus] & tend to stop [hemorrhage] & prevent milk fever” When an infant is first born it is well to wet its mouth with half a teaspoonful of coldwater and give it nothing else until it is applied to the breat 10 while retained will likewise prevent the operation of the remedy by involving it in its viscid substance 14 Chalk & calomel may be used in doses of 1 gr. cal. to 4 or 5 chalk repeated once in 2 or 3 hours 15 Other cathartics which may be used are or as recommended by Dewers 1 gr. carb. sod. to a teaspoonful of water repeated every “it operates” 15 minutes until 10 gr have been given. # Decoction of the flowers of the dandelion & the mullein Senna 2 dr. to with 4 dr. of aromatic herbs or seeds The bile of animals (ox gall) is a good cathartic Perhaps we may consider it as acting as a substitute for the childs own bile. It may be given in [catnap] tea milk etc. # 16 An injection of bitter or 16 aromatic herbs will allways assist the operation of whatever cathartic you use & in mild cases frequently will be sufficient of themselves – superceding the necessity of giving anything by the mouth Continued from p. 8 The stimulus of sound upon the child, crying, irritation of the air upon the skin, and especially muscular motion, excites the peristaltic motion of the child. The influence of muscular motion upon the peristaltic action of the bowels, is considerable, as is seen in horses while travelling, the costiveness of sedentary persons etc. “The warm bath at the temperature of 98 or 100 assists the operation of cathartics renders their action more mild equalises the action of the system and nervous irritation It is especially useful when convulsions are present and may be used at any period except in cases of extreme exhaustion” # It is the most powerful antispasmodic for children [have] acting upon the extremities of so many nerves Jaundice “Jaundice sometimes appears at birth indicated by the yellow colour of the countenance and arising from obstruction of the liver etc. Such cases are generally incurable. The first remedies are the mild deobstructant plant, small doses of calomel etc.” 11 When convulsions are present the warm bath should be used to assist the operation of whatever cathartic is used, to render the operation mor mild, to equalise excitement and to remove irritation. This remedy may be safely used at any period after birth # After the cause which excited the convulsions has been removed, if the morbid irritation of the nerves continues, the bath will again be serviceable 18 Antispasmodics may likewise be used such as valerian, aqua ammoniae, elix. asth. artificial musk infusions of catnip etc. We may use aqua amm. 3 or 4 drops or carb. amm 3 or 4 gr. or asafoetida a teaspoonful of the tinct. in milk & water, or camphor by enema Be [cautious] of giving narcotics to children Some are more susceptible than others. And some children are accustomed to [them] from birth. Case of a mother who had inured a child of 3 m. to bear 30 dr. of SS. I proposed to give paregoric, beginning with 8 or 10 drops, and found that the child had often taken with impunity 31 dr. of SS. to produce sleep 4 – “Child bed women are generally to be treated with mild diet for the first week after delivery, unless their strength has been much reduced by parturition, when they may take port wine in moderate doses” # “If light stools indicate a deficiency of bile the administration of oxgall will be found very serviceable vide [illegible] If acidity is produced, add limewater, If diarrhoea is produced, use arrow root instead of the water, or any other [fecula] Children are apt to receive too much food; hence cow’s milk should be diluted with water. Milk may sometimes coagulate in the stomach of children, in large quantities and occasion much uneasiness Meat should not be given under 6 mo. unless in particular cases which are exceptions to the general rule, where milk disagrees or perhaps in the case of some scrofulous children 12 Acidity Flatulence Hiccough 1 – Very young children are often troubled with acidity, flatulence & hiccough These affections may be removed by a free use of magnesia, lime water, or aqua ammoniae 2 – It will not always be sufficient safe? to administer these articles to the child alone. The mother or nurse must often take them likewise 3 – Sometimes the mothers milk disagrees with the child. This will be known by the constant disorder of the bowels of the child. by the evacuation and pain suffering after nursing both child and [illegible] mother may seem to suffer without a cause The stools may be slimy# The child may cry obstinately 5 – If the mother’s milk continues to disagree we may use cow’s milk diluted with one third or one half water & “sweetened” or with arrow root mixed first with a table spoonful of cold & then with one of hot water, in order to make a homogeneous mixture 6 – Children fed on cow’s milk are more apt to be costive. To prevent this give a little magnesia, decoct. of dandelion etc. Peach tree blossoms are much used, but are too violent in their operation The injection will start the machine again The injection may be made of Eupatorium, catnep, elderflowers mallows etc. etc. Apply first whatever can be first prepared counterirritants for instance. Spirit or mustard to the fat ammonia etc. ammonia to the mouth and nostrils etc. endeavouring to rouse the patient 4 – [A young physician should be careful to know what to do in sudden cases (much depends on a favorable impression at first) Neighbors and friends usually assemble around a child and the expect the physician will be able to prescribe at the moment. In such cases set some of the bystanders to preparing a warm or tepid bath – no matter if eventually if it should not be used. Set others to preparing some other thing and so on. Thus while the attendants are all employed he will be able to devise some course to pursue] I recollect an old physician in this situation who was pressed what to do & replied “stop let us think about it” 12:a. Costiveness & its consequences 1 – Physicians are frequently called upon to prescribe for infants who are in health except that they are costive Children fed from a spoon or bottle are mor to be thus affected than those who are nourished from the breast. If costiveness is produced by improper quantity or quality of the food as is sometimes the case, the diet must be changed 2 – Costiveness if not attended to in time produces flatulence, watchfulness, startings, hiccough, diarrhoea vomiting & convulsions 3 – A physician is frequently called to children I fits, who have been apparently well until the convulsions come on The safest and most efficacious prescription that can be made, is an injection & indeed is all the treatment that most cases will require. Let a warm bath be immediately prepared & the patient put in it if the enema does not relieve. While the convulsions continue the mouth is closed & we can operate on the system mainly by the rectum & the skin 5 Be careful to make your directions for administering an enema very definite, unless you know that the family are familiar with injections Case of a mason’s man hands & knees shooting somewhat off fright rolling over murder The enema may consist of simple warm water, or milk & water, or of tea of thoroughwort or catnep etc. a table spoonful of salt may be added finally castor or other oils may be thrown up in extreme cases the rectum has been filled with lard The water for the tepid 12:b. bath should be about blood warm. Be careful to bathe the child, & not merely to scatter or sprinkle water on it. The length of time during which the child may be kept in the bath may be from 5 to 20 min. While the patient is in the bath if it is sufficiently relieved to be capable of swallowing give a dose of calomel for a child of 6 months 6, 8 or even 10 gr. If improper food is the cause 20 gr. are not dangerous, for infants will bear full doses of cathartics though very small ones of narcotics In bad cases of convulsions the means to which we have it in our power to resort, are external irritants such as garlic draughts to the feet, injections of [nervines] the most powerful of which will be a teaspoonful of tinct. camphor thrown up in a gill of milk & water & the warm bath until we can administer articles by the mouth “If the child be feeble & exhausted upon coming out of the bath give cordials or tonics” Any quantity of food in the stomach & bowels which is not congenial, interrupts the process of digestion & the peristaltic motion functions whose importance is second on ly to that of respiration. When these functions are interrupted the muscles are brought into convulsive action to relieve the system Be particular in your enquiries about food for those who have the care of children are very careless and children will swallow whatever is put into the mouth. I recollect being called to see a very strange worm which a child had voided. The imagination of the attending physician & parent were excited. To me whose imagination was cooler the worm appeared to be a piece of bark I enquired if the child had had no slippery elm bark & found that it had been chewing some. Then the supposed worm was accounted for Rye flour is more apt to become acid than oatmeal # Cal. sometimes by its irritation produces convulsions I have known a family, all the children of which were thrown into convulsion by cal. & I was obliged to be very cautious & use blue pill injections etc. There are several milk remedies such as dandelion which is tonic laxative, & deobstrument acting on the liver, mullein fl. elder [blo??] tea “The pollens of most plants has a laxative quality” I have seen no danger from the prussic acid of the [illegible] flower & it is much used [illegible] from [illegible] also among the French they hold a place the French Pharm. Wild liquorice [gal??] [Circa???] resemble the dandelion Moderate friction excites the bowels Sometimes alkalie or chalk, though generally they are rather constipating, prove laxative probably on account of the acid combining 12:c. II II Where is a tendency to costiveness, the use of oatmeal gruel or porridge will be beneficial or a porridge made of wheat flour with the bran, strained through a cloth & mixed with the milk with which the child is fed also rye meal gruel or rye bran gruel If the health is not affected by the constipation be cautious about giving much medicine. It is always better to cure this affection by food than by medicine. # Castor oil from a teaspoonful to a table spoonful is the best cathartic magnesia given with the milk is a good remedy but not always sufficient. Elixir salutis is one of the most common family medicines. This article with castile soap dissolved in it has been found very serviceable. The gall of animals may be recommended. The blue pill operates gently as a cathartic & is useful in changing the habitual disposition to costiveness. I have prescribed with advantage decoction of the flowers of the dandelion, or mullein. The flowers of the peach tree are much used for the same purpose but “are rather too powerful for ordinary cases” “They are powerful even for adults” & sometimes gripe unless combined with aromatics Calomel may be used with safety # “In severe cases mustard and ginger may be applied to the abdomen” Mechanical manes in the form of suppositories are much used by nurses such as a piece of molasses candy or a roll of paper moistened with oil. They are beneficial. # If the child has been weaned pay particular attention to its food. Nurses are very careless. # “No serious evil will arise unless young & anxious mothers should give medicines and thus make the child sick” “If vomiting arises from dentition we must remove the irritation Give laxatives, as magnesia, & narcotic Children should be early accustomed to the reception of enemata to prevent subsequent prejudices upon the subject. I recollect the case of a child about 12 who was suffering from an obstinate constipation caused by an affection of the lower spinal nerves which produced a partial paralysis of the rectum and bladder so that a catheter had to be introduced & injections were [illegible] demanded. But all the efforts of the nurses (women) were unable to administer an enema Calomel had been given until the mouth was affected, yet without producing an evacuation. Finally the patient went into an insensible state, and injections were given & produced free evacuation. I have heard adults say they would die before submitting to receive an enema. 12:d. Vomiting Spontaneous vomiting in infants arises from over distention of the stomach. The discharge is made without nausea & almost without effort, & consists of pure milk or milk coagulated. The mother should simply be cautioned not to allow the child to nurse so long at a time. # Children and old people vomit with more facility than the middle aged If vomiting arises from the sympathy of the stomach with some other part of the system which is in a morbid state, the primary disease must be first cured & used for the irr. of stom. For the vomiting itself in palliative we may prescribe lime water & milk. a teaspoonful of each; soda water, or any liquid affording an abundance of carbonic acid. Vomiting from irritability of the stomach or free [illegible] requires particular attention. The attendant symptoms will be paleness of the countenance, quick & feeble pulse, & cold extremities. Irritants must be applied over the region of the stomach. They may consist of ginger, mustard, horseradish leaves, mint etc. aqu. amm. [illegible] essent oil dissolved in alcohol” The alkalies such as pearl ash, also soda water “lime water” may be given internally. Excite a discharge from the bowels by injection or a calomel cathartic to remedy the irritated action of the stomach “[illegible] counterirritation” The warm bath will be very serviceable, soothing the nerves of the skin & by sympathy producing the same effect upon those of the stomach nervines also may be given We may try putting a little brandy into the mouth or a small quantity of capsicum tea. Hot cloths & fomentations may also be applied externally. A large bulk of warm water water may be thrown up the rectum in obstinate cases, use stimulating injections.. One of the most convenient modes of administering a large injection is by a pipe fastened to a large ox bladder Press the fingers against the end of the pipe which the bladder is fastened so as to make a valve and prevent the escape of the fluid contained in the bladder, until after the pipe has been completely introduced into the rectum # I used to carry this recipe about me when I practiced in the country Frequently irr. of stom. is overcome by irr. o f the rectum by an enema of salt & water or by a large injection to produce a peristaltic motion downwards 12:e. Ren “Remove the cause, which is frequently indigestion. If it proceeds from the teeth, lance the gums The following is an excellent recipe # in these cases Rx Cret. ppt zii sem. card. zi bi carb. potas. zfs grind aqua bullientis 0 fs Give a tablespoonful every half hour I am inclined to the opinion that the alkalis, such as pearlast act by creating an excitability Emetics are particularly safe for children much more so than for adults. Ipecac is generally the best unless the disease in which the emetic is indicated is very threatening, when antimony should be used Squills are indicated in emetic doses in complaints of the chest “with [illegible] [illegible] but should not be administered when there is much inflammatory action in the system. “Warwick’s powder a preparation of antimony, was once popular and often administered without the advice of a physician. I have known it endanger life Nurses should never prescribe antimony” Some situations are more liable – low situations [seashore] Children shut up in low dark apartments suffer from want of amusement. If a diarrhoea from teething is suddenly stopped the brain is apt to be affected. This affection of the brain is peculiarly liable to occur in children. There is no outlet to the brain 12:f. Diarrhoea This complaint sometimes affects children for months & even years Some families are more subject to it than others & I have known those in which all the children would be affected with diarrhoea from a period soon after birth until they were three or foru years old. The children who have this predisposition to the disease are born with diseased liver and bowels & have indeed all the chylopoietic viscera in a disordered condition. Hence among the causes of diarrhoea we may rank a bad constitution. Other causes are want of cleanliness, bad food “want of sufficient clothing” bad air damp rooms, confinement & want of exercise. Exposure to cold & moisture A bad air probably causes diarrhoea mainly by its depressing influence. The effect of confinement and want of exercise is very great. Young animals suffer in the same way Even vegetables seem to need motion for I think I have observed a great deficiency of fruit & a sickly appearance of fruit trees after a season uncommonly free from wind. Confinement is injurious in another manner Children need mental stimulus from a variety of external objects. I have known surprising cures effected apparently by the operation of this very principle. Teething is a frequent cause & whenever it is we must palliate & check, but may not stop the diarrhoea From the sudden stoppage of a diarrhoea during dentition you may expect an affection of the brain to follow. The discharge from the bowels in this case is similar to that of tears from an irritated This will be convenient in many cases as in travelling Other mints may be used spearmint is most agreeable I have given this in the latter stages of the diarrhoea of adults with advantage Almost any cath. will often check a diarrh. Cal or blue pill is generally best Judgment is to be exercised whether to prescribe an emetic or a cathartic & as to the choice of a catheter Ipecac however is almost always safe children bear emetics well Put the parents & the nurse upon investigating as to [diet] Persons are apt to very careless about giving things to children And they may have wrong notions as to particular articles Prohibit solid oily food, crude vegetables and esculent roots. Potatoes are very bad in diarrhoea so are the analogous roots. They contain indeed much fecula, but also much 12:g. eye, or of mucus from the lungs The expressed juice of mentha vulgaris, boiled skimmed and mixed with white sugar is an agreeable, & useful article for the cure of a diarrhoea, which has continued but a short time & is not severe. In the early stages of a diarrhoea, which is sufficiently severe to demand the attention of a physician it will generally be best to commence the treatment with a cathartic; though if fever accompanies it an emetic of ipecacuanha should be the first article administered. Judgement must be exercised in the choice of a cathartic. Calomel will be best if the child be not particularly feeble or of a very delicate constitution & for a feeble child the blue poll. I myself was for formerly many years unable to take any other cathartic than the blue pill without being griped. Generally it will be best to combine chalk with the calomel, as the latter is indicated for its deobstruent, rather than for its purgative effect. The dose may be about 2 gr. cal. with 5 or 6 of chalk If improper diet is the cause the food must be changed; & it will generally be necessary to be particular in our enquiries with regard to the diet for the parents may consider many things a safe which would be strictly forbidden by the physician. Especially will it be necessary to attend to the diet if the child feeds instead of sucking. Every thing hard of digestion, such as salted & oil food should be prohibited The diet should be arrow root and in case of diarrhoea this article will be improved if prepared with a little laudanum or wine sago taipica, which is probably a hydrate of besides They are apt to become acids & acrid in the bowels. In the Polyn. islands The inhabitants living upon taro are very liable to diarrh. West of the Rocky Mts Lewis & Clark found the inhab. subject to diarrhoea for living on a root [illegible] [illegible] men suffered in the same way after they arrived among them In the evacuations & the evacuations of children shd always be exam [may] [illegible] that potatoes remain undigested Cullen & Rush thought different of potatoes The evac. of chil. should always be [illegible] Pies cakes articles containing much sugar hot bread should be prohibited Bread shd be toasted The juice of meat will often be beneficial No gravy (i.e. artificial or carbonized fat with flour etc.) Potatoe starch, pure, is perhaps not inferior to the tapioca etc. Boiled flour becomes s hard as stone almost hydrate It is an old practice It is an excellent preparation make a porrige of it grated Tapioca I suppose is made by sprinkling casserva root, powdered, with water & baking it making a preparation what appears like gum arabic. I have not been able to learn how it is made, but have made it this way a similar substance of arrow root Arrow root & the tapioca are cooked by first dissolving them with a small quantity of cold water & then adding hot water. In this way [illegible] are avoided 12:h. flour or roasted or baked flour made into a porridge with equal parts of milk and lime water. The bread should be toasted and butter should be used very sparingly gravy not at all. Casserva sago etc. An article similar to tapioca, if not the same may be made in the following manner. Tie up a quantity of wheat flour tightly in a clean cloth & boil it for 5 or 6 hours The result will be a hard substance which is to be grated & “[illegible] milk & water or with lime water” made into a porridge this will be palatable & good Rice in gruel, or thoroughly cooked by boiling The worst cases of diarrhoea are attended with feeble pulse, cold extremities, dry skin, & generally a rise of fever once or twice in the 24 hours. Soften the skin by the tepid bath which is [illegible] etc. and keep up an action on it by flannel unless there is fever & in such cases use also absorbents freely with tonics & aromatics. The chalk julep or white decoction will be as good a preparation as any. Rx Chalk [illegible] zfs to zi pul. cinnam. to zii zii, bum arab zi carb. potas. zi water lb I. boil ½ hour Sometimes [illegible] a similar recipe shd be used” The Europeans add [illegible] use [illegible]” a little laudanum may be added. Of this feed freely, giving say a table spoonful from ½ tab sp. to I once in an hour sometimes. As a tonic the vitriolic or tonic solution of Moseley is inferior to none in such cases Rx zinci sulph ziii alum zi water lbi Give from four to twenty drops. Tonics must sometimes be combined with absorbents Opium is always safe in cases where the bowels have been thoroughly evacuated. It is generally better to combine it with ipecac, which will determine its action to the skin and act as a gentle tonic & laxative The tepid bath is [illegible] as it may be called) relieves the irritation of the bowels through the skin Chalk does not act mechanically or chemically it has a specific action upon the stomach as much as bark Make white decoction in various ways if cinnamon offends use some other spice Sometimes add astringents or [illegible] Tonic sol. sulph [illegible] ziii al. zi Mosely sometimes used al. zii In 3 or 4 gtt it is anti emetic In larger doses it may be emetic & cathartic This is a state of the system similar to the collapse of cholera Asiatica It is a collapse taking place during diarrhoea. I have found advantage from stimulating or acrid injections as salt & water, mustard In chronic diarrhoea opium is often invaluable. Some families are obliged to give it 2 or 3 times a day for along time to their children until they are so old as not to be liable to continual diarrhoea The stools may be green clayey from deficiency of bile sour curdled [illegible] or very fetid, so much so as to be very offensive turning the stomach of the attendants. 12:i. In cases of chronic diarrhoea where there is attending it much sensibility and irritability of the bowels opium combined with diaphoretics cathartics or tonics is an invaluable remedy Sometimes violent symptoms supervene vomiting supervenes & the diarrhoea stops the patients hands & feet grow cold his pulse grows small, & if the most active measures are not take used the patient dies in 24 hours. When this change of symptoms take place we must resort to the most powerful means of exciting counterirritation such as application to the epigastrium of mustard, horse radish leaves ol. monardae punctulae, ol. turpent. etc. Such articles as pimento will be grateful and stimulating given internally We may give calomel, opium & the carbon. acid, and use stimulating injections. “Effervescing mixture with SS. [illegible] appt” Particular attention should be paid to the kind of They may be sour & curdled, or mucousy, [illegible] clay colored, water stools for much may be learned from their inspection. Acid is often formed in the whole alimentary canal, producing sour and curdled stools which will indicate lime water or other absorbents, with aromatics. The acid may arise from fermentation or more probably from secretion Such cases I have often cured by the expressed juice of the spear mint prepared as above mentioned & given freely. When the stools are green white, or clayey, give opium to allay irritation. Ipecac to equalise excitement, & the blue pill as a deobstruent, the latter in small doses so as to move the bowels, but once or twice in the 24 hours. Alkalis are useful as # Noel’s plaister was made of white lead red lead castile soap and olive oil, boiled till the red lead was so far decomposed by the oil that the mixture was of a cream colour It is a smooth plaister and is less stimulating than [illegible] Use soft charcoal by burning cork, which is the popular kind or cedar Dose teaspoonful to a tablespoonful in a convenient liquid Lime water & other alkalies may always be given They may be mixed with the food without [injurious] the taste When the disease has continued long & patient is [illegible] phlegmatic temperament we may bandage the bowels, to give mechanical support [Opium] also will be useful applied externally in this way Adults from the Wt. I. with chronic diarrhoea will look like a mummy Bog water is a very soft water & contains carb. hyd. Astringents [illegible] tinct. vitriol decoct. of oak bark with milk & sugar & spice Bandaging & plaisters Take any adhesive plaster and mix about ½ opium Or soap and opium Acetate of lead is not a new remedy 1 2 or 3 gr a day 1 gr at a time continued as long as the relaxed state of the bowels continues as long as they last lead [cholic] cannot take place for 12:j. are also enemata formed by dissolving castile soap in mallows or catnip tea. If there is much griping with tumefaction of the bowels injections of camomile tea give great relief. In diarrhoea of this kind the following is also a good stimulating & correcting laxative Rx castile soap zi elix. sal. zi dissolve & give it 3 or 4 times a day of teaspoonful or ½ teaspoonful doses. If the stools are fetid give charcoal internally. It will correct the fetor & it sometimes cures the disease. For sour stools vie last paragraph of this lecture During the long continuance of chronic diarrhoea it will of ten be advisable to apply mechanical support to the abdomen. We may apply a plaister of white diachylon [illegible] plaister alone or with opium or of lead and soap & a bandage. In chronic diarrhoea the skin becomes brown, of a dark & dirty appearance, & very dry and husky If the tepid bath does not relieve this symptom, we may apply water from peat swamps, which contains carburetted hydrogen. Vide Duncan’s commentaries In the last stages of diarrhoea we must resort to tonic solution to astringents, absorbents & aromatics we may also use opium with cathartics, emetics & absorbents & If we met with a great craving for salt food it should be gratified. The gratification of such an appetite will prove a stimulus, especially to the mind & consequently the more powerful. We meet with similar cases among adults also. Case of a man who could retain no medicines upon his stomach & finally recovered upon bread & cheese, given at his request In the latter stages also of chronic diarrhoea, acetate of lead the [illegible] [become] very lax and there is generally a prolapsus ani patient being [semiphlegmatic] I saw this article much used in this way when a young man and though expecting bad colic no injury resulted. Prof. Smith was very fond of chocolate [illegible] It sometimes acts like a charm Spiraea may be given in decoction or extract. [illegible][illegible] is not so good being unpleasant having a fishy taste & offending the stomach Ger. mac. & [illegible] [arom.] are pure astringents & unobjectionable on this score. I have prescribed sometimes one, or another, according to convenience of locality where I happened to be The root of typh. latif. is used as food by the aborigines European physicians give [althea] [illegible] which is the true marshmallows Usually when diarrhoea has continued long the kidneys become affected. Mucilage will then prove diuretic probably by their [illegible] affect. The terebinthinates will then be useful. The most common practice in this neighborhood is a decoction of white pine bark especially with a little milk it is called healing to the bowels. There is also nutriment in it for the aborigines, sometimes live on it When mucilages to wear out we may resort to terebinth. The species of [polygnomic] knot grass are 12:k. may be given internally. There will be no danger of the production of colic, by this remedy, for the bowels are too much relaxed. The astringents just mentioned may be various We have at least fifty indigenous vegetables, which may be used given in decoction of milk or water such as the bark of the currant, the raspberry, the various species of oak, of viburnum chocolate of acorns etc. white pine bark in milk etc. the roots of the [illegible] of the [geranium] etc. The viburnum Especially deserving of recommendation are the spiraea tomentosa & cornus circinata. The latter of which equalises excitement Of mucilages we may have occasion to use a variety for irritation for any one article may become worn out & another be more grateful We have typha latifolia, twigs of sassafras, hibiscus, malva bran, flax seed, slippery elm, gum arabic etc. all the mallows, all the [illegible] marshmallows hibiscus palustris called rose of [illegible] in the gardens root is [illegible] [illegible] & sub astringent Sour stools Be particular in forbidding the use of animal food. If there be want of bile, give ox gall, lactescent plants dandelion etc. with mild mercurials; e.g. calomel 2 gr. with 6 gr. chalk. Aromatics also may be combined. Astringents elg. [illegible] speraea cornus & geranium do well. Also the following Rx calc. magn. zfs rhei palm. gr. 8 acaciae zi ol. anisi gtt vi aquae purae zi Give a teaspoonful at a dose. “once in 2 hours” In bowel complaints with griping attended with green or sour stools Rx magn. ust zfs pulv. rhei grs viii pulv. gum ar. zi ess. menth pip. gtts vi water zi dose, teaspoonful Spiraea & cornus used – they are mucilaginous sub astringent & diuretic Articles of a stimulating kind are often needed in the latter stages especially erigeron canadande (colt tail) [illegible] The bitter [illegible] which grows in similar situations (ambrosia [elatio??] is also used as a bitter apparently nervine in diarrhoea Roman wormwood) [Cupron] is acrid, sub astringent & diuretic much used in the middle states improper when there is entonic action case of cholerine cured last summer by this garden young man called etc. chewing the plant etc. The other species of erigeron have similar properties espec. E. phil. Various recipes are given for diarrhoea in children Ex mag. zfs rhei gr. 8 [illegible] zi ess. pep. gtts 6 gum ar. zi The popular remedies are generally absorbent [illegible] mucilaginous astringent etc. Much benefit may often be derived from copious mucilaginous injections mutton broth is the most popular probably other broth (fat meat) would answer still mutton suet is less apt to become rancid. It is thought to be useful also as nourishment I have not though much of this may of nourishing Laudanum may be added Also laudanum & starch injections may be advisable to check the excess of the discharge It will generally be best to begin with about 10 drops of SS. though a teaspoonful may be required vide p. 2 [illegible] 2 12:l. Prolapsis Ani This is a troublesome symptom which sometimes occurs in diarrhoea. The protruded intestine should be immediately replaced. Most writers recommend to do this with a dry cloth, but this will irritate the sphincter ani & make it contract. The smoothest and least irritating article within my knowledge, is the crop of a fowl, or the neck of a bladder, turned inside out & filled with warm water # Afterwards we may apply astringent washes & injections of white oak bark or other similar articles, or of acetate of lead. The latter article may also be given internally in doses of from 1 to 2 grains. It will have a tendency to overcome the relaxation. Astringents are multitudinous & have had a specific [illegible], which proved to be the bark of [?strea] virginica At another time I had a specific sent me which proved to be viburnum sentago all the vib. are astringent Prolapsus ani “The part is relaxed and passes down and is then strangulated by the sphincter. For a permanent cure we must resort to astringents & tonics, but the part must be [illegible] by mechanical means If the intestine is not replaced, [illegible] or suppuration will be the consequence” “Take 1 bladder, cut off the neck, turn it inside out, fill it half full of warm water, and tie up the neck” “This disease was very common at the commencement of my practice but is now rare. The change has arisen in a great degree from the more correct notions respecting the proper management of the mother and child which now prevail. It is possible however that it may appear in [epidemics] and that case we should expect that it would appear for a time and the disappear # It frequently follows other diseases both in children and adults # According to the law of contagious diseases and that it is of no use to prevent it # Heat is a stimulus but too much of it produces a debility which may be [illegible] perhaps in direct debility “Since a free ventilation of nurseries has been practical the disease has been rare. laying aside the use of the preparations of alcohol has also been beneficial.” 13 Aphthae or Thrush White thrush from [illegible] (to inflame) This disease often appears within the mouth is then generally unaccompanied with fever. In some cases it is idiopathic but it more generally is a consequence of morbid affection of the primae viae # It is frequently found in adults of robust constitution which have been very much debilitated by previous that disease infancy and old age are most subject to it & in infants, as was just mentioned it is often an idiopathic affection In some families every infant is several with this affection. The vulgar error however, which very generally prevails that all children have the thrush at some sooner or late period other # is contradicted by the fact that many children as I have known never have the least appearance of it at any time “and it may probably in all cases, be prevented” The most feeble and delicate children are affected with the most violence, hence & from the fact of its being an affection of old age & a frequent sequel of other disease in adults, it may be inferred that this is a disease of debility & this [illegible] will be confirmed by the predisposing causes which we find to be, confined air, a very hot room & improper food# It is caused among the poor by bad air & among the rich by too great warmth & confinement. The fever likewise which accompanies it in many cases is of a typhoid character. # “Caused by neglect of the nurse by want of cleanliness & is often the effect of costiveness” # And have been led to prescribe remedies to prevent the thrush “commences on the inner part of the lower lip & corners of the mouth & extends over the tongue & inside of the cheeks & gums sometimes all these parts are affected & sometimes only one of them” “It appears in small eruptions or vesicles containing a whitish fluid resembling a coagulum of milk these vesicles often coalesce so as to form patches” “extend down the oesophagus to the cardia & here in all known cases it has stopped” Prof. Tully has seen p.m. [illegible] which the thrush the al canal [illegible] “The feces are sometimes covered with aphthous sloughs” “in its severest the eruptions are of a dark brown or deep red colour” “The alvine discharges are very acrid” 14 Symptoms – The disease is preceded by languor and sleeping This is so generally the case that it is common for nurses to say that the child is sleeping for the sore mouth In adults I have observed the same fact, & have predicted the appearance of thrush from the drowsiness of my patient # The symptoms of thrush are very obvious. It commences with white specks upon the lips #, angles of the mouth, & tongue effervescence. # In severe cases the specks in crease in number and size until they cover the whole inside of the mouth the throat & are found indeed upon the stomach x & throughout the whole intestinal canal though this is disputed. One thing is certain, whether these specks or flocculi extend throughout whole alimentary canal or not, viz. that they are found upon the rectum, agreeably the law that the orifices of tubes are most affected The white crust will fall off and be succeeded by one of a darker colour. The coats of thrush are often many times renewed & in this case the formation of a new one is preceded by unusually protracted sleep. A typhoid fever may accompany. It seems to be an eruptive disease determined [illegible] the al. canal. “In its milder form it is confined to some particular part of the mouth or to the mouth itself. The eruption is white & the mouth appears “as if a stratum of coagulated milk were spread over it” & but one separation of the curd like crust will take place. The general health will be but little disturbed” “In severer cases two or three successive crop are formed & the habit being unhealthy, the food innutrient, & the frame weak and atrophous, the under [surface] ulcerates and spreads & a low typhoid fever ensues” # “Your principal object should be to produce an excitement in the bowels by some mild medicine” # Because it is an eruptive disease however diaphoretic seen to be indicated & those which [illegible] action “The treatment is ordinarily a gentle laxative but there is a choice in the kind of laxative. Some practitioners recommend oily medicines, as butter, goose oil, pigs foot oil etc. But these articles do mischief As the vital powers of the stomach are weak, these oils will become rancid” # In such circumstances the oils become rancid & consequently irritate. I never allow oils to be given, yet it is a common practice to swab the mouth with oils, especially goose oil (or [illegible]?) # Chalk shd generally be preferred the other articles dissolve more slowly & may act in part mechanically” 15 It is thought that this disease has often been prevented, by giving soon after birth a teaspoonful of cold water & repeating the remedy every morning, for some time taking care also that the bowels be kept open There may be some foundation for this belief inasmuch as the disease is brought on by heat and debility. “In families where the children have uniformly been subject to this disease. I have recommended cold water as directed that the room should be well ventilated and the child not covered with too much clothing” In mild cases & where the constitution of the child is robust, a gentle laxative will be sufficient to remove the complaint # Castor oil is very often prescribed for it & it may be proper to five it to assist the operation of other cathartics But there are several objections to this article. It does not affect the secretions so much as other cathartics. It does not evacuate the contents of the bowels so thoroughly as others & it tends to # relax the coasts of the intestines, already in a state of morbid relaxation “It will not remove the mucus of the intestines” For mild cases magnesia is the best laxative where it can be given in sufficient quantities. If the bowels should not need a cathartic chalk or some one of the other testacious powders may be given “as [illegible] oyster shells, crabs eyes, crabs claws etc.” # Because it is an eruptive disease however, diaphoretics and articles which translate action seem to be indicated # “Give at first the clear liquor of this infusion and if this does not operate stir it up and give the substance (1) “After the stomach and bowels have been evacuated the ipecac should be given in small doses ¼ to 1/6 of a grain, to keep the bowels open, to produce a tonic effect, to determine to the surface & to prevent convulsion Ipecac has more claim to be considered as a specific than any thing else. It obviates the morbid secretions of the bowels it acts as a tonic never produces unequal excitement or other tonics & it does not like astrigents produce constrictions Whenever there is a tendency to unequal excitement it must be obviated or tonics will do no good” # I rely upon the ipecac though I use [illegible] sometimes especially white root asc. tul. # Indeed “if diarrhoea is present, prepared chalk is a good remedy as is also charcoal: the best form of which is burnt oak for this can do no mechanical injury” # “I have found this almost a specific” Since I have used this treatment I have not lost an infant by this disease” Ipecac in small doses as an alteration approaches as near to a specific in any remedy can # which is not to be expected # Astringents must be avoided, though tonics are indicated because they produce unequal & local excitement & stricture they must be given in the latter stages after excitement has been [equalised] A little borax may be given Moseley’s solut. zinc ziii al. zi [illegible] 1 pt 16 In the commencement of the disease if the symptoms do not indicate the probability of a severe case an emetic of ipecac is the best remedy Antimony has been recommended but it is not a safe emetic for children within the mouth Infuse [illegible] of ipecac in 6 teaspoonfuls of warm water & give a teaspoonful every half hour until the patient vomits or purges. # Ipecac has the advantage over antimony in its tonic and antispasmodic properties & in the mildness of its operation, never producing alarming symptoms # If the ipecac empties the stomach and not the bowels, a blue pill should be given of the size of from 2 to 8 grains. If this be found insufficient, it may be assisted by a dose of calomel, or magnesia or an enema (1) After the bowels have been thoroughly cleansed the ipecac should be given in small quantities a fourth or a sixth of a grain to determine to the surface & to prevent convulsions # If this dose moves the bowels too much, we may add “[illegible] or 1/6” one sixth of a 1/8 drop of Laudanum to each dose The absorbent powder or the white decoction may be given at the same time# Astringents should be cautiously avoided until the stomach and bowels been thoroughly evacuated # “& if there is much fever” Where this has been done we may make use of Moseley’s tonic solution, or cornus [circinata] [illegible] alba, or sericea or saffron safely & with advantage It is to be remarked that chemical action is prevented by the vital principle acting upon the food or articles introduced introduced into the stomach, and putrefactive or [acetous] fermentation if the vital powers of the stomach are [vigorous] This principle applies to vegetables Plants taken up in full blown in August and packed in live [sphagnum] will be preserved by the life of the sphagnum In thrush the powers of life are weakened & not only substances taken in but the secretions themselves are subject to fermentation hance the use of obviating the effects by alkalies limewater magnesia, chalk [illegible] absorbent powders white decoct. Rx. “To prevent the increase of vesicles of effervescences, syringe off the acrimonious fluid as well as you are able, by some diluent or detergent gargle and expedite the separation of the sloughs by invigorating astringents” vide Dr Good vol [illegilble] p. 30 “A little borax & ergot may be put into the mouth. But if the mouth is dry & parched, this and other astringent shd not be used. In such cases we should give mucilaginous substances as gum ar. slip. elm. or sassaf X 5 or 6 gr a drachm? of each in a gill of water # or viola pedata (parsley violet) or comfrey We must be very cautious about administering it to infants 17 To correct the acidity which often attends this disease we may administer prepared chalk or lime water & milk Or Rx magn. usta 10 or 12 fr. elix. pareg. xx gtts water zi given in teaspoonful doses every hour If the stools are watery and the child is robust give coct. ppt # vi gr. cal. 1 gr or the compd powder of chalk in doses of vi gr. or a small quantity fo rhubarb instead of the cal. For watery stools give dal. 1 gr & chalk 6 grs or compd powder of chalk It is too much the practice to scratch or rub off the aphthae in a violent manner with a brush or swab. As well might the cure of any other eruptive disease be attempted by violently rubbing or scraping off the pustules. Rubbing the mouth with a brush or swab until the bleeds is a cruelty which ought to be deprecated Still something must generally be done to the mouth in order to satisfy the importunity of nurses & prevent their mischievous attempts A little borax and sugar X is as safe as any thing If the mouth is dry it may be lubricated with muc. gum arab. slippery elm or sassafras twigs When the mouth is in a very high state of irritation probably a small quantity fo sugar of lead would be serviceable. I have not myself ventured to administer it to infants within the mouth For the proper local treatment of ulcers vide ulceration of the mouth From the sympathy which exists between these parts and the surface, tonics should be combined with diaphoretics I have given [illegible] [has] or [illegible] it is [illegible] observed by tonic and determines to the surface # It is mucilaginous sub-emetic & diaphoretic. It may be given freely as a wash or administered freely internally laxative diaphoretic soothing antirritant “The other [illegible] may be as good” The disease of which we have been speaking is a local disease 18 Ipecacuanha in this disease is emetic, tonic, diaphoretic etc. alterative & since I have used it I have not lost a single infant with thrush The viola pedata (parsley violet in some degree resembles ipecac is its qualities & may be internally administered in its stead # “give a teaspoonful of of the decoction” The peculiar kind of thrush of which I have been treating is a local eruptive disease of infants but as it appears in children more advanced it a critical determination of diseased action. It is not unfrequently a favorable symptom, particularly when it succeeds strong morbid action & [illegible] early in the disease In the latter stages & when the system is exhausted it is unfavorable For instance in hydrocephalus, when the whole mouth will sometimes become sore, and the disease seen to be translated to the mouth “from the brain to the muc. memb” In the latter stages of any disease not so fatal as hydrocephalus it is a very dangerous symptom of exhaustion “In cholera infantum it is a dangerous symptom. [illegible] there is not translation from [illegible] essential part” 18 ½ Eruptions in General Children of all ages are subject to various eruptions These are generally occasioned by the quantity or quality of their food. They are frequently cured by change of diet alone & the greatest attention should always paid to the diet is managing them Oily food particularly nuts, must be strictly prohibited, as they often cause eruptions. I have known some adults invariably affected with eruptions about the lips or other parts of the face after eating freely of walnuts Fish & poke week may likewise [illegible] the eruption We may use the tepid bath for the purpose of cleansing the skin. The frequent use of the [illegible] bath is important especially in chronic eruptive diseases of children & adults vide p. 21 & p. 20 For infantile [illegible] [illegible] p. 1831-2 of Good Case of a peculiar eruptive disease vide [illegible] [illegible] P. 1831 1 [illegible] art. The eruption was periodical, appearing at a certain hour every day At first a light coloured opaque elevation of the skin about half an inch log & a quarter broad like the sting of a bee or wasp. Soon after their appearance blood began to ooze from them & producing a drop which concreted into a scab, & at the end of 3 days fall off 8 or ten eruptions came out daily. Treatment was ineffective until a change of air & diet, which effected a cure “Child 8 or 10 yrs of age about 5 p.m. it would complain of a pain in the face then would appear elevation of the skin to the number of 10 or 12 the issue was treated as if [illegible] bark was tried also nit. sil. sulph zinc. arsenic & other minerals emetics cathartics new diet finally fruit was recom ate freely of oranges & was benefitted. Then change of air & travelling were tried or the first day the eruptions diminished & on the third disappeared In such cases try changes of mineral waters & dieting” 19 Red Gum Allied to thrush is that eruption called red gum The original word was red gown (from a sort of spotted red calico) which has been corrupted into red gum It is called by [Willa??] strophilus intertinctus It is a populous eruption & said to be peculiar to children but this last is doubtful The eruption is sometimes confined & sometimes diffused over the whole body. The papulae rise above the skin are distinct from each other & of a rarely contain lymph bright red colour. The vesicles contain by [illegible] only & terminate in scurf. Afterwards subsequent eruptions makes their appearance. The constitution is rarely affected. Physicians are not usually called unless the nurse is inexperienced Nurses give saffron Some physicians suppose this disease to be the same with aphthae. Dr [Willan] thinks they alternate. Dr Russell remarks “I think that aphthae of infants is of the same nature with those eruptions called red gum & differs in this respect that one disease affects the skin & the other the internal surface of the alimentary canal. Dr [illegible] thinks that this affection, preceded by sickness, arises from causes similar to those of aphthae, such as confinement, heat, irritable state of al. can. indigestion [illegible] If the disease be suddenly repelled from the surface, vomiting & spasmodic affections take place. Hence the European physicians Belonging to the primary [page] Probably the patient was not dieted so strictly as was intended & I recommended change of air Oranges however were beneficial. The was too fond of good living, fond of oily nuts There was a slight reappearance after it but of short continuance It was called [illegible], but improperly The eruption was preceded by a warming sensation of pain in the part. “Red gum is an eruption of fine pimples of a red colour affecting infants [illegible] within the mouth. It is a disease that rarely requires the advice of a physician The cure is much better effected by diet and [regimen] by the exhibition of medicines Still the physician is frequently called in and he must prescribe something if for no other object than to satisfy the friends In order any case give a decoction of saffron & snake root to keep the eruption from [striking] in & keep the bowels soluble with tinct. rhei compd tinct sennae magnesia, or other mild cathartics” 20 caution is not to expose infants with this eruption upon them to a current of cold air, or to plunge them into a cold bath. It is said that fatal consequences have resulted from such imprudence The child should be kept clean & be subjected to daily ablution of tepid water. Particular attention should be paid to the quantity & quality of its food. If the eruption should be repelled from the skin the tepid bath will be the best remedy This disease often occurs within the mouth & rarely requires the attention of the physician. [illegible] tone of the mildest of the eruptive diseases “We may give a decoction of saffron crocus? & snake root to prevent the eruption from striking inwards & keep the bowels soluble by mild cathartics such as magnesia & rhubarb. Still more will depend upon diet than upon medicine. Wine & water or one part milk & three water may be given” [belonging] to p. 18a “In managing most eruptive diseases more attention should be paid to diet than to medicine. In most cases it is requisite that the quantity of food should be diminished. If the food is milk, let it be three parts water, or substitute whey. Infants should take no animal food & no crude vegetables within the year. Oily food and the various kinds of nuts should be prohibited even for 2 or 3 years. A strong child in the country, with abundance of air and exercise might be indulged in such excesses with impunity when a feeble child in one of our cities would be destroyed by them” The eruption is so small as not to be observed It is not my object to treat of eruptions in general with minuteness but to give the general principles of treatment food etc. There are many eruptions met with [illegible] children which cannot be classed or be found described There is an affection of children appearing within the weak, which is not described at all. In three or 4 days after birth elevations of the true skin not of the cuticle upon the hands and arms & various parts of the body containing pus and [illegible] or as large, some of them as ½ dollar high [illegible] [fever] I have seen but few cases they were mortal. The books in such affections direct bark & tonics. The practice proved injurious. The disease as I have seen it has been inflammatory and required antiphlogistic treatment It may however be typhoid sometimes perhaps. If so it should be treated accordingly. I have seen but 3 or 4 cases. There were inflammatory. I prescribed in all these cases & from an analogy more fancied than real, between this & [illegible] Eruptions are generally caused by improper quantity or quality of diet. The remedies frequently get the credit of curing the disease when the amended diet cured the patient Oily & highly stimulating food should be avoided. All the nuts one of the worst is the pea nut 21 Strophilus candidus In this species of strophilus the papulae are larger then in any other of the genus. They are not surrounded with an inflamed base. They are very distinct smooth and shining & appear like little pearls under the skin of about the size of half a millet seed. They may continue for some time. A close examination is necessary for their detection. They appear on the bosom & chest They may accompany other diseases I have seen them accompany cholera infantum in the last stages & considered a fatal symptom [illegible] dyspeptic consumption a dangerous symptom The chest appearing to be covered with an oil surface, looking like particles of water I have seen persons attempt to wipe them off as if water had been sprinkled on the part Belonging to p 18 ½ Apples pears and fruits etc. Cleanliness also shd be strictly practised [enjoined] robust children, much in the open air, may have eruptions about the face mouth etc. with impunity when with the same diet delicate children, much confined, would have fatal eruptions, diarrhoea cholera infantum etc. The appearance of the [former] [have] [illegible] and the parents are often much alarmed. The disease is not dangerous however, & leaves no scar behind A scab is formed & the margin continues to suppurate and matter forms underneath “There is a thin [illegible] discharge from the part & the scab comes off leaving a thing pellucid [illegible]” The disease continues & this film is thrown off & the process is repeated 2 or 3 times It is sometimes occasioned by dentition sometimes it is an effort of the system caused by disturbance in the al. can. “A prejudice sometimes prevails with respect to this disease that it is an effort of nature & ought not to be checked It is a loathsome disease extremely unpleasant to both to the patient and the nurse & if allowed to continue some time it would not be safe to stop the evacuation, at least without keeping the bowels open” Some [Phys.] recommend partic [illegible] as specifics. Cal. or blue pill occasionally may be advantageous Buckthorn has been much celebrated in this and other eruptions It is drastic& hydragogue It is perhaps milder in form of syrup. Many families keep it. Half a dozen berries will operate If there is much plethora, the neutral salts may be given Magnesia also both for the indication & as a corrector I have known the muriatic ether much prescribed, but have not used it much myself, substituting for it mur. ac. as below 22 Crusta Lactea This is the [illegible] larvata of Bateman It appears on the lips, forehead & scalp in small pustules yielding pus, which eventually coalesce & form large loose scabs & perhaps extend over the whole face, down the neck and over the whole body. This eruption never leaves a scar behind it however long it may have continued. The skin is left smooth It is more unpleasant than dangerous, as the children affected with it are fleshy and otherwise health. When it has continued a considerable period of time, we must be cautious of checking it, as it is like a habitual discharge from an ulcer Treatment It is very common to give laxatives, such as syrup of buckthorn, neutral salts, magnesia etc. The sweet spirits of sea salt (diluted muriatic ether) is a very popular remedy. IT is given in doses of from 5 to 10 drops, diluted with water & repeated 2 or 3 times a day. I have seen this medicine given in hundreds of cases & am inclined to think it sometimes of service. It, at least give satisfaction to the parents & does no injury. If there is great irritability give 2 or 3 gr. of cal. with chalk. In cases where I have thought proper to remove the eruption. I have given the muriatic acid instead of ether, prepared in the following manner Rx mur. ac. zi alcohol zi Give [3] drops night & morning diluted with water make [oxyg.] oint. by adding the nit. ac. to lard until decomposition ceases, and the resulting ointment is tasteless. It has about the consistence of wax. Some add sulphuric acid but this is not decomposed & is acrid Sometimes the ointments seem to irritate & then we use [illegible] The best is the sulph. pot. zi to a porter bottle of water. Sulph. of soda does not materially differ, but it is unpleasant smelling like bilge water. In different cases apparently similar I have tried ointment & succeeded in one, but failed in another, & succeeded by waste I was led to adopt the use of sulphuret of potash from the analogy between its solution & the water [of] sulphur springs “We may with advantage make application of dry powders arrow root roasted flower hair powder taking care to give a cathartic when we check the discharge. We should pay particular attention to the diet both of the child and mother making the food weak & [simple] Laxatives will commonly be removed; a little magnesia & sulphur so as to move the bowels once or twice a day “A discharge like this may be checked with safety at the commencement, but when it has become habitual it should not be stopped unless a drain is made & kept open in another part.” 23 For this eruption I have found the oxygenated ointment, very efficacious in removing the scabs & healing the sores It is always safe if well prepared. ‘It is made by decomposing nitric acid with lard’ Perhaps the [citric] ointment (nitrate of mercury with lard) may be equally efficacious, but it is less safe. A good ointment may be made by mixing calomel zii with simple cerate zi or mutton suet zi The sulphuret of potash is one of the best remedies for this & other similar affections Dissolve zii in a pint of water & give a table spoonful night and morning also let the part affected be washed with a solution of twice the strength “It sometimes [illegible] two or three days and [illegible] [illegible]” Some prefer sulphuret of soda sulphuret of lime would also be equally efficacious Such solutions small like bilge water & are analogous to the water of sulphur springs I have sometimes used the sulphuret of pot. as an unguent. Sometimes liquid applications & sometimes unguents will succeed best, & if one fails we may try the other “Calomel ointment may be applied about the edges” If the eruption should suddenly dry up & fever ensue, a dose of calomel should be given & be followed by a few drops of antimonial wine 3 or 4 times a day or a small quantity of ipecac. White hellebore may be given Sometimes the eruption degenerates to a phagedenic ulcer. In such cases I have used charcoal eternally also a variety of poultices. I have seen much The const. irr. may expend itself upon the skin or upon the gland. syst. or upon the al. can. etc. We must be cautious about suspending them suddenly “It is important in all kinds of eruptions to keep the skin clean and soft & to effect this we should prescribe the warm or tepid bath, every day or 2 or 3 times a week. It removes itching and irritation, is always safe and almost always beneficial” May be caused by teething or by food etc. Such things often withstand various remedies & hence are prescribed for very empirically 24 benefit derived from the application of roasted flour. It absorbs moisture & excludes the air Eruptions attendant upon Teething Children are very commonly affected with eruptions when teething. They generally put on the appearance of a fine rash, but sometimes consist of distinct pustules containing matter As they are symptomatic merely, they require no particular attention to be paid to them & will disappear when the teeth get through. The worst consequences might result from their sudden suppression; as if this mode of action by which the system relieves itself from the irritation of the teeth, be interrupted, there is great danger that the system will relieve itself by morbid action of the brain, or other parts more essential to life Eruption resembling the itch Another kind of eruption appears on children of one or two years of age. It sonsists of distinct pustules like those of chicken pock, which form a scab, continue to inflame about the edges & contain a watery fluid It usually makes its appearance in summer & if not cured disappears spontaneously at the commencement of cold weather It has often been mistaken for the itch, and attempted to be cured by [?dock] root, but without success. The sulphuret of potash used as above is a good remedy The tepid bath is apt to be neglected but shd not Dock root often fails in this. It is often very successful in children’s eruptions. It is a very old remedy (centuries) Sometimes goes into oblivion & is again revived Prof. Smith thought most highly of R. patientie 6 feet high in gardens. Woodville mentions R [aquaticus] I know not that either is better than our [common] [illegible] I prefer the [Robtusifoli??] or [horserock] It is acrid and acts well when ext. [applied] and is good int. like rhub. R. crispus also has about the same properties but is milder. R. sanguinea is kept by many for it is as a specific for cutaneous eruptions. called also jaundice root & used in jaundice I have used them all and cultivated than all The leaves of the R. sanguinea have all red veins. You will often have such cuticles exhibited to you in families and be [illegible] of about them. Hence the importance of a knowledge of their prop. I have never known them in any but the children of [foreigners] I am inclined to think the taint may be dormant. The eruption at first resembles what is called “horn pock” “sometimes resemble a [illegible]” The nurse was changed & though the new one was health yet the ulcer appeared on her nipple 25 I think this kind of eruption might be cured by diet and the warm both. In all cutaneous affections the warm bath is very important to relieve the skin from every thing that may obstruct perspiration Eruptions & other irritations of the skin translate action from the viscera. Where irritated action exists in the viscera they are symptomatic Gutta rosea of drunkards is an instance of translation of action from the liver “When a cutaneous eruption appears we may generally apprehend that the al. canal is disordered” I cannot too strongly enforce attention to diet. Nothing will avail without it Venereal Eruptions These appear infants born of parents tainted with syphilis, though they may have no symptoms of it at the time of the birth of the child. Some physicians are of opinion that this child may inherit the disease from its ancestor the parents having been apparently free. The eruption appears in smooth hard, circumscribed elevations of the skin of about half the size of a pea 7 resembling a wart before it has seeds. They continue to increase slowly in size for two or three weeks, & become soft, containing a watery fluid in [honey] like substance Subsequently the skin gets rubbed off & leaves an ulcer with ragged edges & sometimes resembling a chancre which is very difficult to cure. I have known one instance in which the ulcer was communicated from the child to the breast of the nurse. Children affected with this Eruptions sometimes depend upon morbid state of the liver analogous to gutta rosea of drunkards Prescribe to the liver “The disease often proves very obstinate” Mercury does not seem to act as in the primary disease Corr. sub. given in this way is as safe as any other article The bowels should be kept free “I think the sublimate acts more on the skin & is therefore preferable to other mercurials” The plantain was once celebrated for the cure of cut. aff. I have known the plaintain in this way apparently cure after mercurials had failed Still the mercury might have prepared the system The plantain is an old English remedy for bites of spiders etc. It is treated of by Woodville & [Willan] It has as little acrimony I have some confidence in its efficacy. There is an old story about a snake & [spider] I have known nondiscript eruption which had resisted the prescription of several phys. cured finally by diet & change of air 26 complaint have a pale & bloated appearance & the powers of life are feeble Treatment. Change the nurse if derived from her Give corr. sub. in doses of 1/30 or 1/40 of a gr. Give the blue pill in moderate quantities but it subl. is better Give the tepid bath. Try the preparations of iron, such as the mur. ferri, or tartr. ferr. or the alkaline solution of iron. This complaint is not so easily cured as the primary [illegible]. Sometimes it will resist the operation of mercurials & all the treatment for scrofula. In this case send the patient into the country & try simple vegetable articles especially the expressed juice of the plantain (plantago major) externally and internally. It is a popular remedy for poison & is apparently valuable. I have known patients cured by the use of this, and of the air of the country. Still I think its main virtue to consist in its bland & mucilaginous quality [In these cases the whole lymphatic system is disordered & deobstruents are indicated. Now the expressed juice of most green vegetables id deobstruent. For instance the farmers make use of green rye in the spring for this purpose] Perhaps the expressed juice of the green plantain is deobstruent Infantile Erysipelas is an improper name vide Gray [illegible] of Erysipelas Good’s is an entirely different disease and his account will completely [illegible] Corresponds perhaps to the rose of the W.F. Goods account of the rash may do pretty well The infantile erysipelas of Europe described in the books is a different thing # Resembles shingles this is accompanied with fever The primary affection is of the al. can. therefore the attention is not to be directed exclusively to the skin I commences with [illegible] [illegible] you are to prescribe to the fever [illegible] This disease is distinguished by the eruption resembling a rose in the shading off of the colour from a dark rose to a light colour & in the concentric circles As I have seen the disease the rash has appeared in patches about the [illegible] thighs principally & the local affection gave no [illegible] and was trifling while the constitutional fever was severe and dangerous. The fever if not broken up in the commencement will resemble a severe case of [autumnal] remittent I have found no satisfactory account of the disease in the books, not even in the W. P. writers. I have however been informed a conversation with W. Indians that the rose is one of their most severe and dangerous infantile diseases fatal in a week and is treated by a vigorous administration of calomel # I have never seen the infantile erysipelas described as occurring in the European lying in hospitals contagious & terminating in gangrene I have seen common erysipelas upon infants however 27 Infantile Erysipelas The classification of this disease id doubtful. It answers tolerably well to the exanthesis roseola of Good “but [illegible] febrile” there is no species in Bateman & Willan which corresponds to it Efflorescence in blushing patches, gradually deepening to a “dark” rose colour, mostly circular or oval, alternately fading & growing brighter chiefly on the legs with irregular appearance somewhat like concentric circles if the patch is not circular the general circumference This is a disease of rare occurrence with us I have met with three or four cases. It is a severe and dangerous disease, apparently the same with the dangerous rose of the W.F. As it appears with us it is very different from the erys. that described by European writers & which is sometimes epidemic in their hospitals. In children in this country it is generally a disease sympathetic with a morbid state of the bowel The elevation of the skin is less than in erys. of adults the discoloration less deep in colour & the skin though a little tumefied is as smooth to the touch as if not diseased In the cases to which I just alluded, the erysipelas began upon the thighs & extended all over the legs. It was accompanied with considerable fever & a hot dry skin The colour of the efflorescence was purplish rather than red ‘We rarely see watery or bloody vesicles, as in other erysipelas’ I evacuated the bowels thoroughly with calomel (for the sake of the excitement rather than the evacuation) & rubbed the part affected The fever will much resemble that of infantile remittent “The spots are in patches from the size of a dollar to 5 or 6 times as large They are shaded in concentric circles from purple in the center to a lighter colour” “If the disease is not checked there will be increase of fever, constipation and tumefaction of the bowels irritation of the stomach affection of the brain, [illegible] death” Administer a full dose of calomel in the first place and repeat it once or twice. Work off the cal. with other cathartics. The secretion excited by the calomel is what we want. The cathar. subsequently given bring away Antimony in small quant. & nitre may be given until the liver is subdued “When the febrile symptoms run high pulse tense, tongue furred skin hot it is a very dangerous practice to apply discutients applications to the eternal affection Acetate of lead applied externally will probably translate the disease to the bowels” “Treatment I first give colored in full doses to alter the secretions to change excitement and promote evacuation, but do not depend upon it as a cathartic I then give [illegible] or [illegible] & [illegible] etc. to move the bowels I afterwards use the absorbants or alkalies, or ant. or iped. in small doses, as the case may require 28 It is attended with constipation & tumefaction & [illegible] of the bowels; with hiccup & severe fever, & may terminate fatally with severe coma “Pulse small & frequent child dies usually on the 5th or 6th day” “Dr Dewers says that in the cases he has seen the disease was not local but would spread rapidly over the body disappearing in one spot without leaving a trace behind it & breaking out in an other & perhaps a remote part thus changing from one end of the body to the other” Treatment. “Evacuate the stomach with an emetic, as ipecac” Clear the bowels thoroughly with cathartics, for the sake of the impression on the system. Give calomel in a dose of from 5 to 10 grs. If it do not operate within three or four hours repeat the dose. If necessary , work off the calomel with senna (or scammony?) adding aromatics if the stomach is irritable or with castor oil if the senna fails using also some laxative injection & the warm bath to assist. Then keep the bowels open with blue pill & “use some mild diaphoretic as aqua amm.” or give antimony from from 1/20 to 1/16 of a grain Pay little regard to the eruption and direct your attention to the bowels I have letters from physicians who have followed my directions & treated the disease not as a local one but with cathartics which testify the complete success of this plan of treatment. In the W.F. also where the “As palliatives after a strong impression has been made on the bowels by calomel, we may give sweet spirits of nitre, aqua ammoniae etc.” I have tried various either applic. without benefit I have “In those cases when the treatment wa local only the patients have uniformly died. I have not lost a single case to which I was called with commencement. I have conversed upon this subject with medical [illegible] out from the W.F. and find that the practice there coincide with mine” “When called to cases of some standing I have endeavoured to arrest the progress of the disease by a blister as [illegible] in gangrene & in the erysipelas of adults. The disease would extend beyond the blister just as if none had been applied” There is an erysip. affection which occurs about the head of children which resembles that of adults which I have treated with lead water 29 disease is frequent it is treated by the physician with calomel & cathartics. They give calomel 10 gr. & repeat it in 5 gr. doses until 20 gr. have been given I once saw a child with a swelling on one ankle supposed to have been produced by the sting of a bee or bite of a spider, which had resisted the operation of poultices & lead water. I gave cathartics but they did not operate, & the child finally died External applications of any activity should not be used, Still it may be necessary to apply something in order to satisfy the parents. The best will be roasted four “dried [illegible] [illegible]. Warm bathing will be very useful. If treated with lead water & cathartics not used, probably every case would be fatal. I have blistered in imitation of Dr Physick, but never with any advantage ‘If the disease be followed by diarrhoea give absorbents & aromatics such as compd powd chalk or white decoction. If followed by weak pulse etc. give tonics’ I have not lost a case when called early ‘This disease is supposed by some to be hereditary I have seen it affect infants on the scalp when it appeared to be a local affection merely In cases of this kind I have used lead water with [illegible] continualy advantage & without any evil consequences’ Cathartics however should be more or less employed in conjunction “afterward aromatics or tonics as the case may require” ‘It sometimes affects the brain’ [illegible] a more [illegible] or [illegible] intertrigo an attenuation & sometimes abrasion of the cuticle. The vessels forming the cuticle are diseased and the skin is formed in an imperfect manner It occurs also about the nates, [illegible] etc. where the skin folds upon itself & the air is excluded sometimes an acrid discharge Cullen thought it a very thematic affection. The skin looks like a new skin upon these parts. it arises from want of cleanliness & from confinement. The stomach may in a state of indigestion secrete an acid and the skin may secrete an acid. Exercise cleanliness treatment in general of eruptive disease When [illegible] flax they would burn a rag and put it in an axe & rub their finger on to harden the skin when chafed. A scorched rag is beneficial & use absorbent powders first nit. [illegible] might be used keep dry the parts Nurses apply “powder post” which is made by [worms] Sometimes it is a vesicular eruption which upon the head is called [farrigo] & in some situations is called ring worm To the [illegible] or intertrigo occurring in various parts the nurses sometimes apply the membrane from suet which is smooth keep off the air, prevents farther chafing and does well. The absorbent powders as starch alabaster etc. do well 30 Sore Ears This forms a very important subject in treating of the diseases of children. Nature has chosen the part behind the ear for eliminating irritation from the system. Under this head I shall speak of purulent discharges from the cavities of the ears & nose Slight blisters and ulcerations behind the ears of infants are very common & are in most cases, so mild as merely to require washing with cold water weak soap suds & with cold water, & being covered with a scorched rag or with roasted flour, to prevent irritation from the cap Frequently the discharge is acrid & excoriates the adjacent skin. Often a miliary eruption at the part commences the disease & is followed by excoriation Affections of the brain are sometimes relieved by a discharge from this part. The discharge is very important to children in time of teething & when affected with bowel complaints. If suddenly stopped fever may follow with full pulse, tense constipated bowels & fulness of the fontanelles & “often nearly all the symptoms of hydrocephalus” cold extremities Blisters behind the ears will generally restore the child to health When an infant is suddenly attacked with symptoms of hydrocephalus [illegible] disease, enquire whether it has had sore ears which have suddenly dried up, & if so, apply blisters behind the ears, for without them nothing perhaps will cure the new complaint. The same is true of old sore legs stopping of the [illegible] & other charges The theory of this, in all such cases, is the necessity, not The quantity of evacuation will not amount perhaps to more than a teaspoonful & the fullness of the fontanelles [rain] in the head & plethora is not owing to the quantity of fluid. The same plethora, pain in the head etc. will result from cessation of catamena which discharges will not amount to more than a table spoonful So you may bleed to the amount of pounds in cessation of a slight discharge for an old sore leg with out relief. while if you start the ulcer again by [illegible] or [mustard] the symptoms will be relieved Case of a man with ulcers on the legs of 10 to [20] years standing discharge stopped [illegible] pleurisy & aff. of liver the discharge restored by [illegible] blisters caustic etc. cure affected Sulphate zinc 10 gr. to oz or 2 oz may be applied Solution [illegible] sil. is one of the mildest application for irritated surfaces vide infra Oxygenated [illegible] is mildest & less apt to become acrid Sometimes when the aff is of an erysipelatous kind [illegible] relax the parts & are injurious Change the nurse also if necessary If the child is fed upon milk by hand, add perhaps a little magnesia or lime water Similar affections may affect the cavity of the ear & the cavity of the nose. If the cavity of the ear is affected in this way & neglected ulceration is apt to take place & the small bones affected causing deafness. First reject milk & water or carb. soda etc. [illegible] Finally if these means fail use stimulating injections myrrh finally [vit.] sil. In the use of [illegible] sil. external began with 5 grs to the oz & increase if necessary to xv or xx to the oz 31 of the evacuation, as is generally said, but of the habitual action of the system. This affection sometimes degenerates into a very troublesome ulcer, extending down the neck, accompanied with much pain & yielding a discharge so acrid as to excoriate the skin wherever it touches it Deep sores will be formed & the affection may terminate in gangrene & death In such cases it may be proper to apply emollient poultices of bread & milk; to which may be added poppy leaves, or pulverized stramonium seeds or ac. plum. Powdered gypsum is one of the best applications Alabaster gypsum is the finest kind Some apply red precipitate but gypsum is far better. Case in which this alone cured; Another physician advised red precipitate The oxygenated ointment if well made is a smooth dressing for them & is the best kind of ointment, where ointments do not disagree, as it sometimes the case. The bowels should be kept open with cal. or blue pill. It will sometimes be necessary to correct the milk of the nurse by administering magnesia & confining her to a simple diet Troublesome & sometimes fetid discharges on the internal surface from the ear arising from a kind of eruption may follow this eruption & may cause deafness if neglected I have known also the cavity of the nostrils & the frontal sinuses affected in the same manner. A cure may be affected in either case by exciting the discharge behind the ear though it may be necessary to keep it open for some time If this fails use (in addition?) milk & water Milk 2 part water 2 part lime water 1 part Tinct. of myrrh if the discharge is fetid & troublesome a teaspoonful to a gill, as an injection for the ear Sol. nit. sil. 1 or 2 gr to oz. water? externally Be very careful in watching the symptom Case of a young man who had had such a discharge for years checked by astringents [delirius] inflammatory fever ertc. bled cathartics etc. Porrigo galeata ([helvetea]) Cuticles below the scales dotted, shining Said to be contagious. I have never happened to see it so though I do not doubt the fact. I have never seen more than one in a family have it A very troublesome complaint The hair becomes pale, perhaps the roots are affected in which case mercury is indicated. Salivation seems to do no good I have seen it practised without any benefit Recent cases I have cured very speedily with oxyg. ointment. Any smooth substance applied to the part & excluding the air, will often cure as for in stance a bladder, or the membrane of suet what is useful also for [fret] Poultices do well, whether upon this principle or moisture changing secretion When a student I recollect there appeared a strong recommendation of poultices A physician of my acquaintance prescribed a poultice & left his patient. It adhered the hair grew into it and the hard crust formed a helmet indeed. It [was] a long time a period of week, before it was removed When it came off however, the disease was removed! 32 Tinea Capitis. Scald Head porrigo This is a local affection & yet much influenced by diet. Sometimes however it affects the system, or is sympathetic of a general affection of the system. The disease consists of scaly eruptions, eventually covering the head with a hard & generally brownish coloured crust. The hair often comes off. Cleanliness holds of course the first place in the list of remedies; the head should be carefully shaved and washed repeatedly with soap and water. Perhaps as successful a mode of treatment as any will be to shave the head closely and apply a bladder or affect skin in close contact with the skin. It excludes the air. Sulphuret of potash zfs or ai to a porter bottle used as a wash & given internally tablespoonful 3 times a day has cured the complaint in a few days mercurials or corrosive sublimate will be useful, but do not always cure. Sulph. prt. internally zii to lb i [illegible] ext zii to lb is [illegible] The ueast poultice is good, but care should be taken that it do not become dry on the head, which should be first shaved. The oxygenated and the citrine ointments have been found useful, as had also the tar ointment which is made as follows Rx tar ziv wax zfs sulphur zi or is Mercurial cathartics should be given from the first and particular attention paid to the diet. # vide last par. The practice in this complaint has been quite empirical & a great variety of remedies, have been popular. Veratrum viride & v. albus & [apocynum] [androsaem??] olium have used for external washes. Syrup of buckthorn is recommended as a cathartic. Muriatic acid Lunar caustic about 6 grs. to zi of water (rain water) well water may decompose it Decoction of cocculus indica, is given internally & externally. Cal. zii al burnt zfs red lead zfs z6 zifs spermaceti cerate head shaved & washed with soap sude every night and afterwards apply this ointment. It is given by [illegible] & Bates [illegible] & called Diet must be attended to Terebinthinate ointment as tar ointment Tar ointment is made of tar and lard or tar & simple cerate There is no difficulty in the diagnosis of the disease. You will be called to prescribe for scalled head and you will find that the nurses have not mistaken the disease. It begins with small pustules the matter [illegible] which is acrid and soon forms a scab over the whole head. The treatment must be principally local. But mercury may be given occasionally. I have not derived much benefit from the common mercurial ointment. Citrine ointment is good however. Also cal zif lard zi 33 has been used 3 or 4 drops in a wine glass of water Finally the sorts of the various species of dock (rumex patientia, crispa obtusifolia, sanguinea, aquatica etc.) have been much used All the species have about the same properties, being acrid purgative etc. They are given internally as cathartics, & externally applied, made for instance into an ointment, by pounding up the fresh root with lard. The following is a recipe Rx yellow resin zii best ale lb i finest flour ziii mix the all & flour thoroughly together & add them gradually to the melted resin. # The tepid bath may be used when this is used always take care to have a supply both of hot and cold water in order to keep up the proper temperature. Ipecac may be administered to equalize excitement in some cases, & as a valuable substitute for this article we can use the root of asclepia, tuberosa, which is expectorant, diaphoretic and laxative. “Vary the remedies according to their affect soften use decoct. rumex particularly r. obtusifol. called horse dock. It at firs increase, the irritation & secretion. Use it externally & internally” The excitement of the al. can. is affected also of the nervous system Various cutaneous aff. different kinds also of local inflammation, or erysipelatous phlegmous gangrenous scrofulous the inflammation varying according to the constitution scrofulous gangrenous I have frequently heard Pres. Dwight speak of the pain he experienced in cutting his wisdom teeth suffered extreme pain for a whole summer She did not appear to me to look like a person in the consumption I was puzzled [illegible] [illegible] I looked into her throat and mouth and found she was cutting r wisdom teeth # The irritation may continue for mouths, from the pressure upon the gum Those who commence cutting teeth at 10 mo. to a year or even later do not necessarily suffer more Delicate & scrofulous children suffer more 34 Dentition Among the causes of infantile diseases no one more claims the attention of the physician than dentition. The bowels and the nervous system are always more or less affected by it & to this cause we are frequently to refer affections of the lungs of the brain, of the ear, of the skin, of the glands, & of the cellular tissue in general. On this subject there is however a difference of opinion, for it is said by many medical men that children which are healthy # well teeth with as much ease as adults. Allowing for the peculiar irritability of [illegible], no doubt they do, but in granting this we concede nothing, for adults often suffer extremely from dentition. I well recollect the case of a Mrs Waters perhaps about 20 or 21 a married woman and the mother of said to have a [illegible] several children, who was supposed to be in the last stage a good deal of cough etc. had raised a little blood on consumption & upon examination & found was cutting the four wisdom teeth. The gums were divided & antispasmodics administered, when she recovered perfectly. # Case of Mrs Purcell’s child had been sick with diarrhoea and fever for some time a flush of fever coming on every day. I had previously extracted defective teeth from the [illegible] mouth. I now looked into the mouth lanced the gum over a double tooth gave no remedies The period of dentition commences at different ages times in different children, varying from the fourth to the sixteenth mouth, but most commonly in the sixth. The two central incisors of the lower jaw appear about the sixth month and are followed in about a month or six weeks by the corresponding teeth of the upper jaw. very [illegible] [illegible] [illegible] cases I have known a double tooth cut first in others an eye tooth in others all the teeth at once You must always examine to see what teeth are cutting You will perceive the gum swollen and harder Some children are born with teeth but such teeth re merely attached to the gum and are useless and should be removed Sometimes there is too much anxiety about dentition generally however not enough Case of a child mother called me insisted upon # irregular distributions of temperature are [illegible] [illegible] hot 5 [illegible] cold 35 Next come the inferior lateral incisors & after these the corresponding teeth above About the twelfth or fifteenth or 20th month appear the anterior molares & are soon succeeded by the cuspidati those of each kind in the lower jaw cutting through before those in the upper. Next we have the posterior molares. The last molar teeth are not found in the child & hence their name, dentis sapientiae. They appear from the 18th to the 25th year. The above is the order in which the teeth commonly appear, but they often come irregularly, sometimes the lateral incisores, sometimes the molares, & in a few rare instances the cuspidati appearing [illegible] Some persons never have more than two incisores in each jaw Occasionally we meet with families who are said to be destitute of teeth. I have known a family from Charleston, who had this peculiarity. The fact however is in such cases that the teeth exist but not rise above the level of the gums, so that they are not ordinarily seen Such teeth have this advantage, that they are not subject to decay & are also very serviceable. Whenever between the fourth and the eighth 2nd year? month symptoms of irritation exist, the cause of which is not obvious, the state of the teeth must be examined. The symptoms of difficult dentition are fretfulness inclination to bit hard substances, putting the fingers into the mouth, slavering, starting in sleep eruptions about the face & on the scalp, flushings in the cheeks. # hot head pupils contracted sometimes dilated sometimes losing their brilliancy In delicate children the eff. will be more chronic & in vigorous more acute The system relieves itself often by evacuation and this is considered often a good symptom as [illegible] there is a great flow of saliva. The system relieves itself by diarrh. by salivation by sweating [illegible] by every mode of equalizing excitement which is the great principles on fevers & indeed in most diseases 36 and cold feet, irregular paroxysms of fever, remitting fever vomiting diarrhoea irregular & green stools wine small in quantity & voided with pain or in large quantities and of a pale colour bloating of the hand feet and face contracted pupils. All the symptoms indeed of extreme irritation may be met with & we likewise find in many cases a tendency to phlegmonous inflammation suppuration in various parts of the body particularly in the ear. Case of a child who was thought to have an affection of the brain. A tumour was found under the arm. Sometimes dentition is accompanied with phlegmonous local inflammations in different parts of the body & suppuration of the glands about the ar by which relief is afforded Ricketty children cut their teeth more slowly than others but not in general with greater difficulty. The child must be held, and the fingers keep in the mouth to keep it off the tongue # The guard being made with a spring, so that when pressed upon the guard will yield and permit the lancet to descend (in the slit of the guard) 37 Treatment. The first and most important indication is to divide the gums with a gum lancet or other convenient instrument. The operation is not usually painful the child will even press against the edge of the lancet. The relief is often immediate and permanent Some relief may indeed be afforded by rubbing the gums with a hard & polised substance & by giving the child something of the same kind to bit, but the most effectual relief will be afforded by the lancet. The chief difficulty in the performance of the operation consists in confining the child. It may be done while the child is asleep & often without waking it. We must also be cautious not to cut the tongue To prevent this it would be better to make gum lancets with a guard # For the double teeth two incisors should be made & it may be necessary to make a transverse one in order to divide a band of a sort of ligamentory substance which confines the tooth. It is sometimes objected to cutting the gums in particular instances that, if it is done too early, the cicatrix formed by the healing of the incision will subsequently render it more difficult for the teeth to push themselves through This is not true for the cicatrix though apparently harder [illegible] less vitality in it than a part which has not been wounded and will be more easily broken through Solution of continuity is more easily made by disease in a cicatrix than in a part which has not been wounded vide J. Hunger. It is a common maxim that an old scar is apt to break out in to a sore The gums should be divided as often as there are any symptoms of irritation, until the teeth Some other diseased action may exist in the system, and the irritation of the teeth be superadded the lancing will only relieve the latter # For the gums having been exposed for a long time to irritation because [illegible], and perhaps ulcerated and are kept irritated by contact with the hard tooth 38 get through I have repeated the operation three or four times upon the same teeth. In some cases however cutting the gums relieves the symptoms only in part. Indeed the irritation sometimes continues after the teeth get through # “use astringents” If any disease from the causes attacks the child during the period of dentition it will be very important to remove all irritation from the latter source, for otherwise all the symptoms may be aggravated & a disease be rendered mortal which would otherwise have been mild. In children of a vigorous constitution dentition is often accompanied with inflammatory symptoms which require an antiphlogistic plan of treatment. Lancing the gums will then be useful as local bleeding & it may even be advisable to bleed from the arm though a few leeches behind the ear are preferable. It must not be forgotten that in infants, the bowels afford a great outlet to diseased action and to irritation: hence the frequent occurrence of a spontaneous diarrhoea. If the patient is costive or if it has a diarrhoea, a dose of calomel should be administered & if the bowels are soluble a milder mercurial, as blue pill may be given. During the whole period of dentition the bowels should be kept open by such cathartics as the state of the system may indicate, such as magnesia, rhubarb etc. adding aromatics if the system is relaxed and debilitated & chalk if there is acidity If a diarrhoea suddenly stops and vomiting supervenes, externally irritant to the [illegible] [surface] generally, injections, calomel The skin shd be kept moist for diaphoresis is one of the most powerful means of equalising excitement etc. If there is much perspiration you may depend upon op. alone but whenever there is much [unequal] excitement opium alone will not do well and ipecac shd be combined with it in small doses # Also by drafts to the [illegible], by local irritants to the skin generally also keep the bowels from remembering that there is no outlet to the brain 39 and the warm bath are to be used, as has already been mentioned under the head of diarrhoea Another & a powerful mode of equalizing excitement & relieving irritation is by diaphoresis. For this use the warm bath & small doses of ipecac & opium or of antimony and opium. Opium will always be useful to allay irritation & particularly if combined with ipecac or antimony, & always safe when there is no determination to the head Small blisters behind the ears relieve the symptoms of dentition & prevent the disease from terminating in hydrocephalus. # If these cannot be kept behind the ears mercurial ointment or cantharides may be applied to the same part. Nervines may be employed either with our without ipecac During dentition exposure to dampness & to currents of air should be carefully avoided & the patient should be kept warm X summer & autumnal epidemic Indeed the effects of it sometimes continue through the winter The desire often resembles spasmodic cholera in the premonitory diarrhoea & the sudden collapse 40 Cholera Infantum This disease appears in New Haven in the month of July August September & October. It rarely commences until the latter part of July & in October there are few cases except those which have commenced in one [illegible] other mouths & continued until this. Indeed cases are sometimes prolonged till the middle of November Symptoms. It begins in various ways; most commonly with diarrhoea, which may continue for days & even weeks without any very alarming symptoms; At other times times with violent vomiting & purging accompanied with high fever. The discharges from the bowels very much in their usually [illegible] from natural colour [illegible] [irritated] [secretion] appearance. Sometimes they are yellow, brown or green, sometimes in small quantities & slimy and bloody & at others in large quantities & watery, smelling like water in which putrid meat has been washed. Worms likewise may be found in all these various sorts of discharges “dead in the advanced stages” The disease is usually accompanied with great restlessness & often with severe pain, which increases by paroxysms at intervals of from fifteen minutes to two hours The pulse is usually quick and weak, the head hot and the extremities cold. The fever is ordinarily remittent but the exacerbations are frequently quite irregular The disease is attended with thirst often [illegible] and after drinking the child vomits. The eyes often appear languid and hollow During the whole progress of the disease [volvulus] may occur Be on the look out for it “The termination of this disease in hydrocephalus I have reason to think is more rare than is commonly supposed. Many cases of this kind occurring in my practice, I have reason to believe were cases of volvulus Or varying from cholera morbus of [illegible] [remittent] bilious fever sometimes putting in the form of cholera of [illegible] at others that of remittent bilious fever 41 while in other cases they may have an unnatural brightness as in pulmonary consumption indication a high degree of mental [illegible] excitement “of bad symptoms” Sometimes the eyes are half open during sleep, as is indeed the case in various bowel complaints of children when severe we often find the diseased action translated from the bowels to the head and terminating in hydrocephalus. Volvulus also may be another termination. Sometimes the vomiting ceases for several days and then returns, while the diarrhoea continues the whole time Duration As to the duration of the disease, it may be very rapid in its progress & terminate fatally in forty eight hours, or continue for months, & the symptoms may vary very much during the progress of the complaint. A damp hot atmosphere will aggravate all the symptoms, while cool weather with the wind from the northwest will mitigate them. In different seasons also cholera infantum will have symptoms peculiar to the year, varying in this respect like other epidemics Finally when it proves mortal, the child is carried off in convulsions, or is worm out with emaciation & dies with aphthae while in some cases death is ushered in by hydrocephalus, volvulus & other diseases Causes. We may consider the cholera infantum as an epidemic sometimes an endemic confined to a particular season of the year analogous (in its grade of action) to the cholera morbus o f adult “This disease is perhaps most analogous to a remittent bilious fever varied by the peculiarities of the [illegible] [illegible] will see in [Jackson] all that can be said in [favour] of the opinion. The very fact that it is often [illlegible] disproves the opinion besides the fact that the disease does not occur at all seasons during the period of dentition The disease is affected by the state of the atmosphere being much aggravated by a damp state of the air always minded by a cool bracing northeast wind The kind and gentle excitement produced by nursing is important in chronic disease “Children should not be weaned till dentition is complete or till 1 ½ years & in the fall” 42 infantile constitution” Dentition has been considered by some as the cause of cholera infantum but to this opinion I cannot assent thought it is held by Dr Jackson & many of our most respectable physicians Dentition may indeed be an exciting cause; it often aggravates all the symptoms & accelerates the fatal termination yet in the winter spring & months it does not produce the disease of not unfrequently children are affected with cholera infantum without any appearance of dentition Worms sometimes make their appearance during the progress of the disease but they cannot be considered as a [illegible] or cause of it. When they exist during the complaint the irritation which they produce must be obviated by such anthelmintics as are not contraindicated by the state of the system. “I think I have seen the [illegible] productive of unfavorable effects.” The cholera infantum probably arises from the same remote causes as the (cholera morbus) & the bilious remitting fever of adults such as damp hot confined air (which can be counteracted only by exercise in the open air) want of cleanliness & bad diet. Improper food may be both a remote & an exciting cause & the same is true of a bad state of the atmosphere muggy or [illegible] of inequality of temperature & exposure to cold. The predisposing cause produced by these remote ones is debility Children weaned in the spring are mor apt to have this complaint, & do not bear the disease so well as those at the breast. I would therefore advise that in places where cholera infantum prevalent. children should be weaned in the fall 43 Some consider malaria the cause Like dysentery this is a disease translated from the surface to the first passages. The fever is of that kind which Sydenham calls febris introversa the action being of an irritated kind in general & rarely of an inflammatory Commencing at the skin & breaking up the balance of the system by obstructing the perspiration the morbid action is transferred to the mucous membrane of the intestines & involves the liver, pancreas & all the glands immediately sympathizing with them. Indications. The indications are 1st To evacuate the first passages; if this has not been already done by the disease itself 2ndly To translate action to the surface & in general to equalize excitement 3dly To excite healthy secretory action and regular peristaltic motion of the bowels 4thly To avoid the causes of irritation and to remove irritation when it exists 5thly To restore the tone of the system & particularly of the stomach and bowels 1st When the disease comes on like the cholera morbus of adults, the stomach and bowels are sufficiently evaluated by the disease generally when the phys. is called and no evacuation s are to be used. It is to be treated like cholera morbus with aromatics as essence of peppermint, with Laudanum We must be careful not to prescribe for the [name] of the disease nor necessarily pursue the plan of treatment generally proper. Often you will find the patient so much debilitated at first as to require stimulants & acrids When we have the collapse stage and a collapse may recur in any disease then the practice of the nurses is correct in acting on the skin Some recommend large doses of cal. [illegible] much smaller the [common] Dr Jackson recommends large doses common in the commencement. Dr [illegible], 1 gr. doses and salt & water I recommend cal. from 1 to 10 gr Though sometimes small doses repeated may change the secretion better than large, yet often a large dose will operate more kindly, then a small one [which] merely irritates “Dr Dewers recommends injections of salt & water 2 or 3 teaspoonfuls to a gill, instead of cathartics. Repeat the injections till full catharsis is produced the morbid action is changed, by translation of excitement from the stomach & small intestines [illegible] [illegible] with cal. ¼ gr. every [illegible] to alter secretion 44 with counterirritants, as mustard, horseradish & brandy on the epigastrium & abdomen with the tepid bath & with injections of starch and laudanum. But when it attacks with a diarrhoea, accompanied with occasional vomiting unless the constitution is very feeble constitution [illegible] extremely delicate the stomach should be evacuated by ipecac and the bowels by calomel or blue pill To vigorous patients & often give in the commencement six grains & would not hesitate to give 10 grs of calomel & an hour after give from one to ten grains of ipecac according to the age and vigour of the patient for in this way the stomach and bowels are more thoroughly evacuated than by giving the calomel after the ipecac has ceased to operate In some cases a single dose of calomel will thoroughly evacuate the bowels, but in others it will only remove the contents of the stomach and small intestines into the colon & a dose of castor oil must be given or one of senna with aromatic seeds The southern physicians, make less use of cathartics and depend much upon stimulating injection, as of salt & water 3 teaspoonfuls to a gill. This practice does not succeed well with us. They also give smaller doses of calomel. This also I cannot approve for a large dose of calomel, ten grains for instance, will evacuate the bowels copiously and kindly, when small ones produce scanty stools, with irritation of the stomach and tenesmus. I may mention also that the French expectant plan of treatment adopted in Philadelphia will frequently be utterly inefficient. Where excited has not been equalized, calomel or any other cathartic may act upon the duodenum only and not produce Such facts as there have been given rise to the opinion that the disease arises from stricture but then the al. can. may be subject to unequal action as much as the skin # a castor oil with elix. sal. aa zi every 2 hours # Yet this practice shd not be adopted indiscriminately where there is weak morbid action accompanied with coldness of [surface] etc. the exhaustion of cathartics will be injurious This is the most important principle in the cure of diseases Sometimes cath. cure the diarrhoea, where the action is unequal. For instance the lower intestines may be torpid and the feces accumulate, the bowels above may be irritated and a diarrhoea of [small] liquid stools may pass by the feces 45 If calomel or any other cathartic produces watery stools in which are small pieces of feces of an ordinary appearance, and there have not previously been copious evacuations, we may conclude that a thorough evacuation of the bowels has been prevented by a spasmodic action of the intestines which has constricted them in places, & confined, perhaps a large quantity of fecal matter. Indeed this may be proved by the success of the treatment, which should be the administration of a dose of opium with a little calomel to change action followed at an interval of one or two hours by a dose of z ¼ and z ½ castor oil or elixir salutis teaspoonful #. It is of the first importance in all typhoid diseases, particularly in those affecting the bowels, that thorough evacuations should be made # 2ndly so translate action to the surface and equalize excitement This indication will be answered by an emetic at the commencement, as already directed & by small doses of ipecac, repeated throughout the disease, & also by small doses of mercurial medicines opium being conjoined in many cases, as will hereafter be mentioned. In some calls where there is much arterial action antimony is preferable to ipecac & the lancet or leeches may be indicated but such cases are rare This indication is also answered by applications to the abdomen of fomentations, with decoctions of aromatic herbs sinapisms, blisters, burdock leaves, horse radish leaves, ginger in spirits aq; amm or the Ulceration of the bowels is generally preceded by aphthae both are effects not causes of the disease “An [epispastic] should not be applied after aphthae have made their appearance. If the pat. is languid & sleepy we may suspect aphthae.” Diluents may be used Obviating irritation by opium is often necessary to have the proper effect of cal. for instance Give opium first & follow with cal. & often you will succeed in obtaining the effect of the cal. when you had failed before “Ipecac when it acts as a cathartic is more apt to produce fecal stools than any other article 46 terebinthinate oils An epispastic upon the epigastrium is very useful to relieve irritation of the stomach & to prevent ulceration of the bowels and aphthae. The warm bath will tend powerfully to equalize excitement will relieve vomiting, quiet restlessness, produce a uniform perspiration & if used at evening, procure a quiet nights’ rest. It may always be used and at any time, unless the patient is in a state of exhaustion. As a substitute for ipecac, the root of the asclepias tuberosa may be used. It is much used in infantile diseases as diluent, to determine to the surface & to promote expectoration. 3dly For changing the secretion of the stomach and bowels and keeping up a gentle peristaltic motion I have found small doses of mercurial cathartics with ipecac of opium superior to all other remedies. If any article deserves the name of a specific in any disease, it is ipecac judiciously administered in cholera infantum. It relieves this disease with more certainty as certainly as than cinchona does intermittents. It may be observed however that a man successful with one remedy only m ay be compared to a mechanic, very skillful with a pen knife! My method of administering the articles is the following. For a child four months old, mix 4 gr. of ipecac & 5 drops of laudanum in twelve teaspoonfuls of water & give a teaspoonful every fourth or fifth hour & at the same time give so much of the blue pill as to You will know when the blue pill begins to have its appropriate effect by the change in the color of the stools Pills of blue pill may be given without much difficulty to children there is little taste except of the saccharine matter. They may be given in food [illegible] dried huckleberries which I have often called for in the country where there was difficulty in administering remedies. There is often great difficulty with respect to this. A child will often scream at the sight of the doctor Opium to allay the irritation of the stomach and prevent the ipecac from being thrown of Ipecac to equalize excitement & determine to the surface Ipecac also, to qualify the opium # Or if this cannot be done, introduce a paste of opium just within the sphincter # Case of a child in a family where 3 or 4 children had previously died of chil. inf. [Lax] & [illegible] habit etc. I commenced the treatment with the pill and ipecac I treated it mildly giving blue pill instead of calomel N.B. For such cases [illegible] 47 procure an evacuation from the bowels two or three times in [never twice] in the twenty four hours. For a child a year old take twice as much ipecac & laudanum with the same quantity of water and give it in the same way. Sometimes three times the quantity of laud. will be necessary; for instance if the child has been in the habit of taking it or if the diarrhoea is very urgent If the diarrhoea is urgent, it may be necessary to administer injections of starch and laudanum & to apply to the abdomen ginger & grandy volatile liniment poultices or other irritants The enema may be made with three table spoonfuls of flour & about 3 or 4 times as much laudanum as you give by the mouth say 10, 15, or 20 drops. # I prefer flour to starch because the foreign starch often contains acid. The chalk mixture or white decoction may also be used. # “Children of a bucophlegmatic temperament and lax habit are very apt to have this disease & with them I have sometimes commenced the treatment by administering blue pill & ipecac.” The success of this plan of treatment will be strikingly shown by the following case. A child 10 months old was taken sick in this town last summer, with cholera infantum, grew worse and was directed by the physicians to be carried into the country Unfortunately the child was carried to a situation not more elevated than N. Haven & while there its strength decayed and all its symptoms were aggravated. The parents despairing of it recovery returned with it to N. Haven & sent for me with a request that I would do something to alleviate its sufferings On recovery from the disease they usually crave [salt] food and salt is a grateful stimulus 48 I found it in a state of emaciation, with hippocratic countenance frequent vomiting, urgent diarrhoea, with stools fetid, watery and containing some slime and mucus, & leaving streaks of blood upon the cloths. The countenance and gestures, expression of great anxiety, and there were frequent paroxysms of extreme distress. I directed ipecac 5 gr. & laud. 10 drops to be put in 10 teaspoonfuls of water and a teaspoonful to be given once in four hours flannel wet with ginger and brandy to be applied to the bowels & gave 5 oz. blue pill, & ordered the diet to be of arrow root flavored with a little brandy. After the second dose the vomiting stopped, the stools became less frequent & within 24 hours the complexion of the stools was much improved. The next day the same medicines were continued and four drops of the tonic solution with a little brandy and water. On the fourth day from my first visit, the child began to relish salt fish, which was allowed Capt. Dennison’s children To correct fetor in the stools we should give charcoal. Carbonic acid, by injection, is given for the same purpose. The mode of injecting carbonic acid, is to place chalk & vinegar in a bladder, and force the gas into the rectum, as it evolved. “This is recommended. I have tried it but not very thoroughly” But if vegetable food undergoes the acetous fermentation it shd not be used. The putrefactive fermentation however is more injurious than the acetous 49 4thly The most common cause of irritation is dentition The gums should be often examined, & be divided if they appear at all swollen. All kinds of food that is hard of digestion should be carefully avoided though for children somewhat advanced perhaps a small quantity of ripe fruit may not be injurious If the child has not been weaned the milk of the mother will be the best food; for those children’ who nurse are more apt to recover than those that have been just weaned. The act of sucking is highly soothing and gratifying & operates like a nervine medicine. The best food for children that have been weaned, will be arrow root, with a little brandy or wine as a condiment & as a substitute for this & similar articles from the shots, we can direct a porridge made of roasted flour. If in the latter stages of the disease the child craves any particular of food, as salt fish, or salt meat, or wine or brandy, it should be given, & all kinds of medicine laid aside if the stomach leathe3s them; for strong disgust will debilitate by exciting nausea. Frequently however we can succeed in preventing this effect, by a different mode of administering the medecine the sight of the spoon for instance may may give rise to the loathing & nausea. With respect to food we may lay it down as a general rule in such cases that when the powers of the stomach are so weak that food must undergo fermentation in it, vegetable diet should be preferred to animal. For local irritations, various applications should be made & various articles administered, especially in the latter stages “Tea juice? boiled beef a teaspoonful with pepper & salt is grateful frequently & checks vomiting but at first vegetable preparations are better” vide supra The chalk mixture made with a little opium in some cases or with astringents etc. a valuable [illegible] 50 of the disease or when we are compelled to try a variety of remedies. When there is unequal excitement & unequal temperature blisters may be used. Blisters sometimes produce perspiration. To relieve irritation of the stomach effervescing mixtures may be drunk, they are often more grateful. [illegible] we may fill the stomach where there is vomiting and dilute its contents with a tumbler of wine whey I have often succeeded with it with a teaspoonful of aqua ammoniae in it as being thrown up will be no objection. If the disease commences with much irritation in the stomach, it may be useful to overcome it by counterirritation in the rectum produced by an injection of soap suds or of salt and water 3 teaspoonfuls of salt to a gill of water, for a child a year old. Dr Dewers relies must upon this latter article in the commencement of cholera infantum and repeats the injections until the bowels are fully evacuated. He likewise recommends small doses of calomel, a quarter of a grain for instance repeated once in an hour until the bowels are evacuated. In cases of irritation of the stomach & torpor of the liver & portal system, this practice of salt & water & small dose of calomel does well. In chronic cases he gives magnesia rhubarb & opium. With respect to small doses of calomel it may be further observed that they will not answer when the intestines are much coated with mucus & that in some localities they do not answer so well as in other places. On the shores of lake Erie for instance the physicians are obliged to give large doses of calomel than we give There are cases in which small doses seem to irritate & large doses operate kindly “In the latter stages Rx magnesia grs 4 SS gtts Rhei gr i.” C. Florida not so pleasant but loses its mawkish & herbaceous taste by keeping (like peruvian bark) The spiraea is though less inclined to act unequally in this state than most other astringents If one astringent wears out try another Oak barks Rose [illegible] (salix [illegible} “A valuable popular remedy” has mucilage combined seeming to resemble ([illegible]) [illegible] was formerly much used but is now superseded by native articles It is well known that because These astringents are often prompt up is specific [illegible] virginica was specified good [illegible] & [illegible] it e.g. viburn. lentigo, raspberry, blackberry, [illegible] [illegible] root decoction recommended by Dr Rush thought to deter to [illegible] used by many) [illegible] bark has [mucilage] There is apt to be a paucity of [urine] in this disease as well as in Diarrhoea & dysentery and then diuretics are indicated and are highly valuable 51 5th When in the latter stages of the disease the principal indication is to restore the tone of the system & particularly of the stomach and bowels we must make free use of tonic and astringents. Moseley’s tonic solution will be one of the safest and best articles in this stage. If the bowels, by a habitual action keep up the diarrhoea, astringent will be more specially indicated such as the compound tincture of vitriol. I prefer however, the cornus circinata to all other articles C. servicea (red [illegible]) C. [illegible] C. alba nearly allied Of astringent vegetables we can make choice from a great variety which are indigenous & common. All the various species of viburnum all the [potentillas] & the roots of the strawberry to say nothing of the bark of the oak & indeed most of our forest trees, are astringent & may be used The spiraea tomentosa is much used in decoction or extract All the species of [illegible] are astringent & the C. [rivale] is a most valuable article; as is also the geranium maculatum, which may be be given in wine & then we shall have red wine. The sttici limonium (marsh rosemary) is not so agreeable but is frequently more efficacious specially if the mouth is sore. Its taste resembles that of salt mud. When given internally, it is boiled sweetened & has a little wine or brandy added. It is also used as a wash in case of the supervention of aphthae. The erigeron canadense, called colt’s tail & strangury weed has been found a valuable article in the latter stage of this complaint and of dysentery given in decoction. It is acrid pungent like [illegible] bitter & stimulating & acts also upon the kidneys as a diuretic. It seems likely to prove a Give it in decoction or in milk which will cover the taste of it Balsam of copaiba or turpentine cannot be combined with mucilage so thoroughly as in the white pine bark in milk & water diuretic & [sheathing] to the bowels I have often used the expressed juice of spearmint as in diarrhoea q.v. It is important in long continued bowel complaints of children that the medicine shd be grateful The diuretics are useful both in children and adults (dysentery diarrhoea & cholera infant) because there is a paucity of urine and acrid irritating secretions In some cases of exhaustion we give opium constantly in small quantities to keep up the [illegible] Mucilages marshmallows or substitutes for which hibiscus palustris hib. syrica hib. [illegible] hib. (rose of [shora]) Mucilages by stopping irritation are diuretic 52 a valuable article in the latter stages of bowel complaints provided there is not too much vascular action. It has been long used, vide Barton, the N.Y. Medicophys. Transactions etc. In 1790 an itinerant came through N. Haven offering to cure the dysentery; and attracted a good deal of notice. It was found that his [illegible] consisted of this article. The other species of erigeron have similar properties. In the latter stages of the diarrhoea mucilages should be given. They made of any of the various in articles in use, but perhaps the most valuable mucilage, will be that made from the inner bark of the white pine, which will furnish a terebinthinate principle in addition to its mucilage Often in the latter stages of the disease, great benefit will result from supporting the abdomen by a bandage and a plaister of white [diachylon] and opium or a soap plaister (of [illegible] & soap) 2 parts sp. 4 pts plaister In extreme exhaustion & debility from the long continuance of the complaint with cold extremities, aromatics and stimulants may be required & we may give spiced tea spiced wine or brandy in small quantities, or the white decoction and apply cloths dipped in brandy to the abdomen & to the extremities Nothing has more affect upon complaints of the stomach liver & bowels than the state of the mind as we see in dyspeptics The We are apt to suppose children not subject to notice of [illegible] children [illegible] mental impressions. When the matter has been dissolved in grief & abandoned to despair I told them to tray as a last resort carrying the child in a hack out of town the excitability was entirely gone the child might as well die in the back as any where strange advice On the top of the [illegible] about two miles out lifted up the child [sound] trees grass birds, etc. opened its eyes before this had lain with eyes half closed noticing nothing 53 Finally when every form of medication seems to fail, our only remaining resource will be change of air. This is a most powerful remedy. The physicians of N. York and Philadelphia are continually recommending it. We are apt to suppose that in children it can be only the purer air & the exercise of travelling that produces a good effect, when they are carried from home for their health, but on the contrary the change of scene seems often to have a more powerful effect upon them than it would upon adults. Children that have lain sick for weeks, instead of pursuing their accustomed amusement even though mere infants seem of ten to settle into a state of utter despondency from long confinement & the constant sight of the same unvarying objects around them, & appear to loath every thing offered to be done for them. This morbid condition of mind seems to be one directly opposite to that of nostalgia or homesickness & is to be relieved in a corresponding manner. I well recollect a child apparently in articulo mortis cold & vomiting nothing wd [illegible] the vomiting entirely beyond the influence of medicine or food. It was carried in a hack to the top of a hill without the town N.Y. [illegible] where it had a view of the sound, & the scenery of the country around. While there is brightened up vomiting ceased and took food staid an hour or more & then was carried back to town, where it finally recoverd. 54 The symptoms attending cholera infantum very very much and give rise to considerable variety of practice It is probably owing principally to this circumstance more than to any other that physicians differ from each other in their mode of treating it. Post mortem examination show that this disease affects principally the mucous membrane of the stomach & the small intestines; rarely the large ones. Sometimes coagulable lymph is found in the intestines but less frequently than in other diseases. Sometimes the mucous membrane of the intestines is thickening & according to Dr Jackson ulcers are occasionally found both in the small & also in the large intestines. The liver is usually enlarged without derangement of structure Ordinarily the brain exhibits no morbid appearances, unless the disease has made a determination to that part constituting hydrocephalus N.B. The remarks upon asclepias tuberosa introduced under the Head of [illegible] capitis probably belonged here Fever of the bowels Acute [illegible] of [illegible] Different writers give different names and do not always give the same symptoms. The European disease differs somewhat from ours. It is our infantile winter epidemic. Typhus infantum of Prof. [Tully] “Disease of the bowels bowel complaint, plague of the bowels, winter epidemic & [illegible] epidemic. Remittent bilious fever (at south) Musgrave’s spurious [illegible] fever Duncan III or IV” There is some [illegible] action but more of the character of irritation like other infantile fevers Rarely vomiting never diarrhoea in commencement The morbid excitement often extends to the lungs putting on the for [illegible] what is called in adults bilious pleurisy The disease is not common at this time though it was very much so formerly Probably it will return It is almost the only winter infantile disease & so common has it been also that the nurses call almost every disease in winter, of childr, by this name of choler. The dis. is to be broken up in its [illegible] by means various in various patients by a strong impression upon the stomach in a strong constitution but by an impression upon the whole system in the delicate constitution Comparison to a weight upon a [illegible] If applied upon one part only it will break it not if applied to [illegible] It is desirable that vomiting or at least nausea should talk place from the cal. In enteric 55 Constipation with Fever or Remittent bilious fever of children Musgrave’s spurious worm fever marasmus acutis This complaint has been known in N. Haven for more than 50 years by the name of choler. It is called in some places at the “It is unfortunate that we have no better [illegible]” eastward, the plague in the bowels. It is a common bilious “It affects however the duodenum & small intestines rather than the liver” fever produced by causes which operate upon the bowels a part of the system which in children more particularly invites Children are attacked by it from the age of 3 mo. to 2 or 3 yrs. febrile action. It is often inflammatory in its commencement Sometimes it [illegible] in the form of typhus Symptoms The pulse in the commencement of the disease is full, frequent & sometimes tense, the skin is hot and dry face flushed, respiration, short and laborious, tongue covered with a white fur, the abdomen fuller and harder, than in health, & the bowels costive; the urine small in quantity and high coloured & sometimes the fever is attended with cough & expectoration. This disease is a fever which often affects the lungs and always the alimentary canal & liver, the secretions being suspended and the bowels constipated. Treatment. This will be antiphlogistic in the commencement of the fever & the first indication will be to evacuate thoroughly the stomach and bowels. This will best be answered by a single dose of calomel of from 5 to 10 or 15 or even 20 grains for a child from four to twelve months old We shall thus produce a strong impression upon the whole alimentary canal & upon the system at large. In entonic cases and vigorous habits a little tartar emetic may be added to the calomel Usually the calomel excites both vomiting and purging, but sometimes it is retained on the stomach and has no immediate cases it may be beat to conjoin tartar emetic for this purpose. Sometimes the cal acts upon the stomach & duodenum & excites the action of the liver, and spends itself there, without producing catharsis Sometimes it is necessary to repeat 10 gr doses of calomel once in 2 hours until 40 or 50 gr have been given and cause them to follow with liquid cath. a [illegible] or jalap or scammony N.B. If there is great difficulty in giving medicine repeatedly, we may give powder of jalap in coffee or fermented liquor or we may give a teaspoonful of the tincture of (not briony root but pure jalap in milk & water which will not be tasted Feeble constitution must have the warm’ bath. # Rx senna zjs man zi senega zii anise seed zis liquorice zfs [illegible] ½ [illegible] This I have held the child with. remember large doses are needed Rx scamm. grs 2 or 3 chalk & diaphoretic antim. this was called Earl of Warwick’s powder & was kept in the shop here. Tart. emet. would be a more certain prop. of art. It produced violent vomiting. Scammony is better united with cal. however. # # Cautiokn about covering the [illegible] with a blanket vide # Cal. was finally substituted for the [diaph.] ant. This Warwick’s powder used to be a shot preparation in this town and parent would send for it. From the uncertainty of the strength of the diaph. ant. however, [dangerous] vomiting sometimes occurred from the use of it 56 effect. In the latter case a second dose may be given two or three hours after adding from an eighth to a quarter of a grain of tartar emetic for a vigorous patient Fifteen or twenty grains of calomel will often empty the stomach and bowels freely & remove all the symptoms. The calomel may however evacuate the bowels but partially & in some instances not at all merely moving the contents of the small intestines into the large ones. In such cases another cathartic is needed for completing the purgative operation If the calomel appears to have no effect, it should be repeated in 5 gr. doses every three or four hours, the patient put immediately into the warm bath & we should commence feeding the child as freely as the stomach will bear with the following R fol. sennae zfs, mannae zi steep in ½ pint of boiling water & if there is a cough, add senedae zii & rad glycyrrizhe zfs. If the stomach will not retain the mixture of senna the powder of jalap or scammony mixed with tea coffee or milk must be substituted, giving 4 or 5 grains in the intervals between the doses of calomel Injections vide p. should be given to assist the operations of the cathartics and repeated every 2 or 3 hours until the bowels have been thoroughly evacuated taking care however not to commence with injection until the cathartics have had time to operate When we have succeeded in procuring stools we shall find them to consist of viscid green mucus mixed with half digested food. Sometimes in the progress of the disease they exhibit the appearance of small pieces of membrane, of There is a membrane [illegible] inflammation of the duodenum similar to that of croup. This indicated by pieces of membrane preceded however by pain in the part obstinate constipation etc. This is a strong indication for calomel which however will not operate as a cathartic until the violence of the disease is broken Warm bath & injections will also be more particularly In some violent cases of the fever where calomel seemed to have no effect. I have known acid as lemon juice advantageously combined with calomel Among the cathartics and laxatives used in the second stage we have the wild liquorice or [illegible] [circa???] which was formerly a popular article and kept in families. It is diaphoretic and laxative and possesses and also deobstruent properties It is said that with this the Indians formerly [died] their porcupine quills # The acids are sometimes used in combination with mercurials I should not use them unless when mercury fails Sometimes it affects the ear & produces suppuration & discharge. It may terminate in effusion into the ventricle of brain. It may terminate by exhaustion Or may terminate in thrush “in which case there is a double translation 1st from the bowels to the head & thence to the mouth oesophagus & bowels 57 & of about the size of petals of peach blossoms, floating in a liquid of the same colour. Such stools as these latter are a sure indication that a farther evacuation from the bowels is needed vide p. 207 They are frequently evacuated by adults in bilious (or common cholic. If such continue it is well to vary the cathartic and give magnesia, or soluble tartar (peerlash & cremer tart.) or phosphate of soda, or any other neutral salt. generally the violence of [illegible] [illegible] & The blue pill may be substituted for the calomel & given three or four times a day, until the stools change their appearance or the mouth is affected, though this rarely happens to children under four years of age. These stools rarely have any smell & as they indicate a want of secretion I the liver & glands of the abdomen, mercurials are peculiarly appropriate. In some states of fever attended with stools of this kind I have known the free use of acids with mercury very useful # After 48 hours the fever generally remits, and sometimes it continues in the form of a remittent for six or eight weeks or more. Very frequently however it changes its seat in the course of 15 or 20 days & terminate in a phlegmous swelling of some of the glands or in phlegmon or is determined to the head & puts on symptoms of hydrocephalus, which are best relieved by blisters behind the ear, a place which is the natural outlet of diseased action in children. They may terminate naturally by a discharge of purulent matter from the cavity of the ear or fatally by effusion into the ventricles of I recollect two cases early in my practice, which continued 6 or 8 months. They were very violently attacked They continued 6 or 8 months coma Hence we should never despair In the latter stages it may be proper to give tonics or those articles which are called tonic very unlike the vegetable tonics however. They produce a [illegible] excitement Giving arsenic is no new practice It is a safe and efficatious remedy, when the dis. continues as a remittent It comes after cal. & tart emet. producing liquid secretions. If long continued it must be followed by bark to restore tone and obviate the debility caused by the arsenic Arsenic can only be called a tonic as it removes disease. It would never be given as a [illegible] is pure debility # # I have used digitalis, in the latter stages to allay irritation # In many cases the fever continues from habit & medicines have little affect. There will be an accession of fever every afternoon. Here give sol arsen 2 drops twice a day which is a full dose for a child ½ years old If this has no effect give it [illegible] times a day” 58 the brain; in two cases I have known them relieved by a thrush. If the disease continue a regular remittent without symptoms of hydrocephalus, it will be proper to give tonics, such Moseley’s tonic solution or if the fever intermits or remits Fowlers solution of arsenic the latter in doses of two or three drops the former from 4 to 20 drops, 3 or 4 times a day. I have known a child 18 months of age cured in this stage of the fever, in the course o f two or three days by taking 2 drops of Fowler’s solution 3 times a day. This article however is liable to produce edema or dropsical effusion & if it does we must substitute the tonic solut. (beginning with about four drops) or some preparation of bark. The dose of the tonic solution will depend upon the irritability of the stomach If irritable from 3 to 6 drops will be as much as can be borne After the inflammatory action has subsided narcotics anodynes are necessary to remove irritation and to procure rest We may use opium, either alone or better combined with ipecac or antimony # Indeed as the skin is usually dry antimony is indicated in almost every stage. The warm bath also is indicated in every stage except in the low typhus state of the fever when it would be too debilitating. Epispastics & irritants are useful in the progress of the disease, to translate action from parts essential to life & in the last stage also perhaps to keep up the action of the system. They may be applied to the abdomen if it is much swollen to the head behind the ears where there is danger of hydrocephalus & Avoid too much heat to prevent tumefaction of the bowels. Terebinthinates a [illegible] oil may be needed proper If pneumonic symptoms blister etc. “If the lungs are much affected, apply a blister to the chest, give expectorants, and pursue the treatment required in pneumonia. Senega & squills are good, but are too stimulating for the earlier stages liquorice anise” By this disease it is sometimes proper to do nothing and omit all medicines in mania etc. In those cases as I have had difficulty to persuade parent to do nothing. I have applied aloetic plasters to the bowels I think they have produced evacuations injections also can sometimes be given Case of a very [illegible] child [furious] parents passed in review before him with roasted apples pears etc. after 26 hours he snatched an apple relapsed in 26 hours they probably had over loaded his stomach however the same management finally succeeded afterwards of the patient recovered. vide p. [20?] The same season I had 3 or 4 more such cases of mania which required to be cured by fasting 59 a large one to the chest if the lungs are affected. “This disease is sometimes followed by thrush when an emetic of ipecac will have a good effect. If the stools are fetid charcoal should be given. If in the latter stages there should be tumefaction and pain in the bowels, the abdomen should be supported by a bandage. In the latter stages also a decoction of the inner bark of the white pine be useful. It possesses some tonic properties” Sometimes in diseases of children the mind is affected, the patient will take neither solids nor liquids & struggle till it is exhausted whenever an attempt is made to administer any thing. If that is the case in this disease we must use the tepid bath & we may a apply for purpose of moving the bowels, a large plaister of aloes and ginger to the abdomen Frequently this derangement & morbid revengeful disposition (according to Dr Rush an affection of the moral faculty is so great that we must wait even for 24 hours or more without administering any thing. It may require great prudence and judgment in such cases, to satisfy the parents. Before leaving the subject I may observe, with respect to the propriety of the course I have directed in the commencement of the disease, that if the cathartic which we administer first produces emesis we may be sure that the alimentary will be operated on, & also that we often require a remedy more powerful than the disease, just as in croup. “As to diet meat must be forbidden but sometimes salt food is craved. The weak chicken broth is good. The dis. is something very rapid & violent Fever as violent as the constitution could bear Collapse from the violence of action Parents considered the patient & dead After the mustard was applied as soon as the skin was reddened a blister was applied, which produced a sore 2 or 3 months in healing “In one hour pat. revived” Nervous system affected Irregular action such as after collapse of cholera Strong clonic spasms once in 15 min. “Pat. kept under a constant [narcosis]” Antispasmodics & tonics finally In two or three weeks [illegible] recovered some strength It was called the child that died & returned to life again The above is account of the disease as it most commonly appears. It is different however in different years sometimes effecting one part of the system sometimes another A practitioner keeps this [illegible] [illegible] 60 Case of a female child 2 yrs of age. The disease ran the most rapid course I ever witnessed. The whole system became affected; the pulse was full & frequent, the skin hot & the tongue furred. In 24 hours the disease came to a crisis and exhausted the excitability of the system; the pulse grew faint, the skin cold and the respiration languid the patient became insensible & was apparently dying sinapisms were applied to the abdomen, ankles & wrists & heated bodies put into the bed, to restore warmth. After the sinapisms had been on an hour and excited some redness, epispastics were applied in their stead. Ammonia & ether were put into the mouth & caustic ammonia was applied to the nostrils to excite Inflammation so as to blister. Ether was also put into the mouth In about two hours the system was resuscitated. Immediately a train of most violent nervous symptoms followed the chill became convulsed almost instantly. After trying antispasmodics in vain the convulsions were checked by laudanum, 6 drops, every two hours. The laudanum lost its effect in two hours & needed to be repeated. The blister on the chest produced a deep ulcer which was difficult to cure Finally tonic solution was administered. The child recovered Child of Mrs “Moulth???] Child of N. Beers’s vide p. 208 diseases and consequently meets with no new disease For they do not make sudden transition as in botany plants he is guided by symptoms & by the operation of remedies Appendix to Mes. fever acute marasmus This disease sometimes appears in an acute form with great irritation Sometimes terminates in hectic Patient will run down very rapidly [illegible] appearances enlargement & [illegible] of mesenteric glands “Called” consumption of the bowels” or Marasmus” Mesenteric fever is thought to terminate in hectic Probably it does especially in scrofulous patient and in those bad cases where the tubercles with a mesentery ulcerate “The pain in the bowels is no usually very severe but of a continued aching kind generally better removed by [camomile] injections than by anodynes” 61 Mesenteric Fever Marasmus tabes [illegible] [illegible] This disease arises from obstructed glands in the mesentery & is accompanied with morbid secretions of the stomach & liver bowels. It is sometimes the consequence of some other fever. It is often connected with scrofula, & it is apt to be attributed to worms. The disease attacks children of from two to ten years of age. Symptoms. The fever is of the intermitting remitting kind, with irregular paroxysms attended with tumefaction of the abdomen, costiveness, indigestion, loss of appetite & very irregular appetite & with paroxysms of pain in the bowels. The patient complains much of its bowels, but the affection seems to be rather distress then sharp pain & is neither constant nor regular. The countenance is very pale except when the cheeks are flushed with fever & the limbs are emaciated This is generally a chronic disease, but sometimes it is acute, & exhibits strong marks of irritation in the system. It may terminate in hectic. Dissections exhibit an enlargement of the mesenteric glands. Causes. It is sometimes as has been said above, the effect of another fever. Among the poor, with whom it is most frequent, it is caused by coarse and unwholesome diet. Children born of scrofulous or gouty parents are more subject to it & hard labor by the mother during the period of gestation may have some influence in predisposing to causing this disease in the child. Patients in this disease are subject to paroxysms of pain 62 The indications are 1st to empty the bowels and to keep up a gentle peristaltic motion in them 2nd to change the secretion of the chylopoeitic viscera. 3d to remove paroxysms of pain 4th to remove the obstruction in the lymphatics. 5th to impose the digestion & to invigorate the system generally 1at To move the bowels and keep up a gentle peristaltic motion mild mercurials as blue pill or calomel & chalk should be given & at the [illegible] time friction as in almost all chronic [illegible] complaint should be employed, upon the abdomen, and persevered in by the attendants. A very good mercurial preparation, will be a pill of four parts gr. blue mass and one 1 or ½ gr of ipecac adding a little opium ½ or 1/8 gr of the bowels are very irritable. If this preparation is not sufficient calomel may be substituted in a dose of 4 to 6 grains. The tincture of rhubarb has in some cases answered well as a laxative & corrector combined with neutral salts and aromatics 2nd For changing the secretions, we must rely upon the articles just mentioned, and also upon those to be mentioned under the 4th head 3d For alleviating sudden paroxysms of pain injections of a gill or a half pint of camomile tea have been found serviceable. If these fail give a camphor injection The pain is relieved by opium plaister There is but a small quantity of iodine and [illegible] effect appears to be produced than shd result from the small quantity of iodine Neutral salts in connexion with tonics have undoubtedly [illegible] deobstruent powers 63 4th For removing obstructions of the mesenteric fluids burnt sponge has been thought very efficacious. I formerly questioned whether it had any superiority over soda. Now it is supposed that all the virtues of the article are owing to the iodine continued in it. It would probably be [illegible] better better to give tincture of iodine in doses of 2 or 3 drops. Still the burnt sponge containing carbon & alkaline matters may have peculiar properties The neutral salts given with tonics have some influence in removing these obstruction It has been proposed to use mercury by injection for this purpose. I know not that it has ever been tried For the indication I have been in the habit of employing the muriate of lime & here given it in connexion with the mercurial pills mentioned under the first head It may be made by adding muriatic acid to chalk or marble & the dose for a child of 3 or 4 years, should be from 5 to 50 drops, given in tea coffee or milk. It is best to begin with a small quantity, say 3 drops & increase by one drop at every dose until the stomach is offended remembering that the stomach bears the article best if much diluted. The muriate of barytes might be used; also the carbonate of barytes is used in dose of but 2 or 3 grains, it being a powerful article. But iodine is probably the best article that we know of Other articles containing iodine, have been used besides burnt sponge, as [fucus] [nodasus] & vesiculosus [reckoned] vide scrofula mur. [illegible] dose 4 or 5 drops in milk & water for a child of 3 or 4 years increasing to 50 even 100 perhaps This [illegible] is not to [illegible] [illegible] it iodine as to be substituted by the latter We are apt to neglect an old remedy as a new one comes on The tepid bath shd not be used when the system is too much debilitated It excites the action of the mucous membrane and of the skin not affecting particularly the blood vessel add a little spirit to make the opium [illegible] if necessary 64 Muriate of lime has the important advantage of exciting the action of the skin which is generally torpid. Hence also the tepid bath has been used with success in this disease The flesh brush too if thoroughly applied several times a day will have a powerful effect. 5. To improve the digestion and invigorate the general system Carbonic acid is a most grateful stimulant to the stomachs of patients in this disease. Hence soda water and other effervescing mixtures, may be recommended spruce bar also & similar articles, if they agree well with the stomach. Aromatics as ginger & spice may often be added to them with advantage Among the tonics which are used to invigorate the system. Iron is very often employed & frequently with good success. The mildest preparations least irritating are the best, such as the tincture of the muriate, the martial flowers & the alkaline solution. Still iron is apt to cause irritation Cold bathing is a good remedy for invigorating the system but if the patient is much debilitated, a cordial should be administered previous to using it When the patient is much debilitated I have found anodyne plaisters upon the abdomen give great relief (where opium did not agree) I have used Noel’s plaister (similar to dyachylon) with soap mix opium zii with zfs of this plaister & spread it sufficiently large to dover the whole abdomen Children are very fond of potatoes but they should not be allowed, unless cooked so as to be dry and [illegible] and then thoroughly mashed Some vegetables as spinach, [illegible] & asparagus may be allowed but only in moderate qualities Preparations of meal of [illegible], especially fried, are bad Rx dough roll it in flour and then cut into thin slips, twist & bake them for [some] hours An excellent preparation for dyspeptic batter than crackers called twisted bread In making broth avoid adding rice, flour, etc. which will make the compound approach the nature of pastry and be more indigestible. Make broths as simple as possible & season with pepper & salt 65 Under this head may be ranked the use of the terebinthinates which have a valuable effect upon the mucous membrane of the alimentary canal The best article is a decoction of white pine bark, which is milder than any preparation of the turpentine of the shops Regimen. Flannel should be constantly worn next the skin to keep up an action in it. The patient should take exercise in the open air whenever the weather is good & damp easterly winds should be carefully voided as they have great influence in all chronic affections particularly glandular of the bowels. Friction & cold bathing have been already mentioned. Diet. This should be carefully attended to Raw fruits, potatoes and other garden vegetables, corned beef & in short all articles which are not of the easiest digestion or which have any tendency to ferment & become acescent in the stomach should be forbidden & caution should be enjoined that the stomach be not distended with liquids, so as to interrupt digestion. The diet should be dry consisting of toasted bread & farinaceous vegetable substance, as arrow root etc. well boiled & seasoned with a little wine & spice. If meat be given it should be broiled & eaten, with condiments. In some cases a piece of lean beef that has been partly broiled & then boiled, makes a broth that is grateful & sits well on the stomach. But if there is much dyspepsia, broth of any kind a not good If this fever terminates in hectic the mineral acid shd be used Undoubtedly however the affection may be produced by excessive purging vide next page low states of fever in adults also for the state of the bowels occurs much oftener than some phys. are aware of “The gases may arise from the ingestion, from a fermentation of the natural secretions, or, as I think from a direct secretion of gas by the intestines. this alone would see to account for the rapidity of its production” sometimes small watery stools 66 Tympanitis In diarrhoea dysentery & constipation with fever & typhus fever after these diseases have passed the first stage, the bowels of children affected with them, are liable to be affected with tympanitis. a troublesome symptom This state of the bowels may occur of itself about the time the febrile action begins to subside, or it may be brought on at an early period by the use of astringents, or by heat produced, either by too many bed clothes or by hot articles applied to the body for the purpose of exciting perspiration it is important to examine daily the state of the abdomen in children affected with bowel complaints, that a tympanitic state may be obviated, as soon as it begins to appear The abdomen is [swollen] and elastic to the touch feeling tense like a drum head under the fingers We can tell as soon as the hand is applied whether the swelling proceeds from inflammation, or from imprisoned air, for in the former case the pressure will cause pain The proximate cause of this state of the bowels I believe always to be a relaxation of the villous coat of the intestines & a deficiency of peristaltic motion in consequence of both which the villous coat falls down & forms a valve which confines the gas, while at the same time there is a morbid secretion of all the chylopoeitic viscera which [illegible] the evolution of the gas In the first stages of tympanitis, the alvine discharge usually cease even if there had been diarrhea & dysentery before & the little patients exhibit signs constant [illegible] not acute pain of great uneasiness from the unusual distention of the “It is thought by some that tympanitis is always occasioned by bad treatment in not giving cathartics enough at the common [illegible] Such persons probably do not examine the abdomen of their patients with sequels of severe bowel complaints. Tympanitis comes on whether cathartics have been used or not and nothing is more likely to bring it on than an excessive of cathartics at the commencement of the disease” The temperature had been raised above it secreting [illegible] & the child might have died “I am very partial to diaphoretic measures in general but must confess it is often abused If carried to excess it rapidly exhausts the patient also if excessive heat as aplied and the pat. does not sweat.” 67 bowels. In the progress of the disease tympanitis the child frequently comatose. The tympany is not always to be regarded as a dangerous symptom it sometimes indicates a favorable crisis, yet if it is accompanied with coma, there is danger that the brain may become seriously affected. If symptoms of congestion in the thorax exist, the disease of the thorax should claim our first attention, and the tympanitic state of the bowels be treated as a [illegible] complaint Treatment. The indications are to evacuate the flatus and excite healthy action of the viscera of the abdomen If the disease has been produced or aggravated by heating applications too many bed clothes or too confined an atmosphere, the heated substances should be removed, the bed clothes thrown off & air admitted freely to the patient. In the summer of 1814 I was called to a child sick with dysentery whose bowels became extremely inflated in consequence of filling with the steam of boiled potatoes in [illegible] the bed in which he lay The child because if much [illegible] & [illegible] was so difficult that it was thought to be dying; but upon removing the potatoes throwing off the bed clothes & opening the doors, the symptoms were at once amended & in the end the disease was completely removed by the use of a little [cajeput] oil in water and laxatives For removing the flatus of the bowels we may use enemata of the decoctions of aromatic plants or suds, such as catnip, camomile; the seed of fennel caraway or masterwort seeds or the essential oil of such suds may I prefer camphor to any other articles 3 or 4 [illegible] IN colicky complaints etc. I have known more benefit [illegible] injections of camphor in milk & water than from any [illegible] articles and that too after the most violent purgatives had vailed. I know of no article which operates so well in relieving irritation of the pelvic viscera [Anodyne] balsam Rx vol. [lin] zi [illegible] camph “Sometimes blister the abdomen” 68 be injected in milk and water. But I think I have experienced the greatest benefit in the case of children from the injection of a teaspoonful 2 or 3 of the tincture of asafoetida in a gill of warm water. It unites more readily with the water of a little milk is added A pipe of ivory or the pipe of a common injecting syringe may be introduced into the rectum as is recommended in hysteria, for the purpose of evacuating the flatus. I have sometimes used an elastic catheter with success The peristaltic motion of the intestines is to be excited and healthy secretions induced For this purpose we are to apply friction with dry flannel to the abdomen and mild cathartics are to be given. The latter may be jalap aloes rhubarb etc. with castor oil to work them off If frictions do not succeed, we may apply volatile liniment camphor, oil of origanum & finally epispastics We may likewise give internally cajeput oil in 3 or 4 in sugar oil of mint, oil of caraway, asafetida zfs to si etc. which is [illegible] to offer [illegible] its stomach & is not offensive to the taste and magnesia with [illegible] & cubebs [illegible] [illegible] or guaiacum Dr Good classifies [worms] according to their locality yet he makes mistakes as to their locality Much has been under the subject, and the remedies are almost innumerable. It is rather difficult to select the most important parts of the subject 69 Worms This subject naturally follows that of bowel complaints From testimony which cannot be invalidated it appears that worms of various sizes and forms have been found in almost every part of the human body. It is only in the alimentary canal however, that they occur with any frequency and give rise to symptoms, from which we are led to infer their presence Those worms which are of anomalous kinds, or are found in anomalous situations (oftenest perhaps in the lungs & frontal sinuses) as they are of rare occurrence & as the indications of their presence were either very obscure or altogether unknown wanting are interesting only as curiosities and will be passed over, without any notice, except an occasional reference to the fact known with regard to them “Worms in the alimentary canal are so common, as to have given rise to a class of diseases called verminous & a class of therapeutic agents called anthelmintics. The kinds of likewise of worms which occur in this part of the body have been thoroughly investigated & we are in possession of a large mass of information upon the subject I shall consider this subject under the following heads 1st The kinds of worms found in the al. canal 2nd their origin & that of worms in general, found in the body 3d the general effect they produce on the system & the general symp 5th the morbid effects produced by each species, with their treatment 4th the general treatment of verminous diseases 70 II. The genera of the common intestinal worms are three; toenia ascaris & tricephalus Of the tania there are two species. Tania solum or cucurbitana & t. lata or vulgaris. Of the ascaris there are also two specis of a. vermicularis & a. lumbricoides. 1st Tania This a long flat worm varying much in breadth and thickness which is formed by a chain of flat articulations, united by a border or edge. The accounts of the length of this worm are almost incredible from thirty to a hundred feet. Taenia solum (called also cucurbitina or gourd seed worm & the armed taenia) is distinguished by having the head forked and surrounded with papillae or long fangs (holders) by which it fastens itself to the mucous membrane. The broken off joints have when discharged the appearance of gourd seeds. hence its name of gourd seed worm. Taenia bata (or vulgaris the unarmed taenia) has an external form like a ribbon joints scarcely perceptible & is white and seen transparent. The head is narrower & smaller & the papillae not elongated 2nd Ascaris vermicularis & a lumbricoides The first, a. vermicularis (thread worm, pin worm & when existing in number called ascarides) is filiform, slender at both ends & from half an inch to an inch in length & of the diameter of a small thread found generally in the rectum & though not confined to that part of the intestines. It feeds on the mucus of the intestines & produce its young in immense quantities. It is found in the stomach & called maw worm 71 Ascaris lumbricoides (or [illegible] long round worm) is perfectly round & from four to ten inches in length bearing a striking resemblance to the common earth worm It is said sometimes to perforate the intestine with its mouth 3 The trichocephalus now called [tric???] is a small capillary worm from an inch to an inch & a half or two inches in length. The body is about half an inch in length & Is terminated a tail which is twice as long & end in a fine hair-like point In addition to these worms have been reckoned two others the vesicularis & the gordius. The former is a small vesicle found in the brain (sometimes in great numbers) & containing many small worms. It is now considered a hydatid & is excluded from the subject of worms & verminous diseases The gordius (horse hair worm) is found in soft stagnant waters from four to six inches long & twisted into various knots & contortions” Good. They are sometimes found in the earth in great numbers they turn black on exposure to the air & resemble horsehair, hence their name of horsehair worm They are very common in our vicinity They are rarely found in the human stomach. I have known them coughed up in abundance from the lungs; when they had probably come from an abscess in the liver. It gives rise to a severe disease among the [lapladens]. Vide Good. The maggots of the common house fly & the’ larvae of many other insects, have occasionally been met with in the alimentary canal of the human body vide Good What were formerly called vesicular worms are now considered as hydatids. [Brera] or worms recommended An attempt has lately been made to revive the doctrine of [equivocan] generation. The learned advocate has attempted to fortify his opinion by the analogy of vegetables. But where the experiment has been made the seeds of the forest trees that come up as [illegible] may be found at the roots of the young trees Hyoscyamus formerly was common here but is not now However when the gourd is broken in the college yard Hyoscyamus springs up. It has also in the soil brought from a cellar in Chapel St. Leeches & a variety of insect are undoubtedly taken in in water etc. In Duncans [illegible] we shall find an account of a number of caterpillars [illegible] by a child produced by eating cabbage leaves I think I have never known an instance of worms in children while nursing 72 II II. The origin of worms in the human body Worms arise from eggs. Some multiply by depositing their eggs to be afterwards fecundated by the male. Others are propagated by copulation between the two sexes While a third kind of the taenia fecundate themselves. I have spent much time in investigating the origin of worms in the human body but must confess that I cannot satisfy myself upon the subject. It has been supposed that worms found in the human body are produced from eggs deposited by flies about the rectum, at the time of going to stool. Were this the fact, they ought to be more abundant in summer than in winter, while the reverse is the fact. I am inclined to think that the rudiments of worms are contained in certain kinds of food as apples pears, cider water & unboiled fruits and vegetables. In infer this from the fact that worms make their appearance, oftenest when such articles have been taken & disappear when they are avoided. If confirmation of this view of their origin we find that children are rarely if ever affected by then when under three months of age & seldom while they are nourished from the breast. For though some have asserted that they have seen worms in the bowels of children within the mouth & even before birth yet the fact is not well ascertained. Breras opinions, also adopted by Good speaking of the fluke worm There is no doubt of the fact of worms within [fetus in uteri] 73 Brera thinks that the minute eggs of worms are absorbed into the circulation He says “when we consider that the eggs of worms are so small that they are not perceptible by the microscope of Hoffman and these eggs themselves are masses of small eggs, nothing is more probable than that the eggs of worms are absorbed by the lymphatic vessels, pass in to the circulation pervade the system with the blood & are deposited in the various parts of the body, where they enlarge and unfold themselves when circumstances favour their development.” If worms are found in the foetus, the fact will favour this idea that the eggs of worms are carried into the circulation. It may be remarked also that the parts of the body which favour the development of their eggs are those abounding with mucous The hypothesis of equivocal generation is neither specious nor probable. It derives no support from analogy aid from reason, nor countenance from fact In its operation it is worse than useless as it tends to obscure truth by substituting conjecture while it disregards with the most vague and licentious imagination the boundaries between the animal and numeral kingdom & ascribes to chemistry what pertains only to animal life When the creator first gave being to the natural world, every part of the vegetable and animal system was brought into existence by an extraordinary exertion of productive power. They were not moulded by the slow operation of time & the cooperation 74 of mechanical and physical forces, but he spake and it was done. But since that first act of creative power, we find are that these creatures are propagated and perfected by processes more gradual successive and [operose], many of which may be traced by human wisdom and admit of being regulated and controlled by human culture & ability Rosenstein says “from the eggs of a fly proceeds a fly, from the egg of a hen a pullet and not a serpent, from the egg of a goose, a goose and not a fish So from one worm is produced a worm and nothing else” II II II. The effects of the presence of worms in the body When the seed of worms are once developed in the human body, the health is more or less affected, and the morbid symptoms which then appear are in proportion to the number of size of the worms the sensibility of the part they occupy and the general morbid diathese which takes place at the time, whether the cause or the effect of the worms Worms in the alimentary canal are less frequently the original cause of diseases than is generally supposed, inasmuch as in many cases of disease where they exist, the disease was merely aggravated & not originated by the worms & all the symptoms of worms from which it is common to infer their presence, may be occasioned by 75 undigestible substances for a diseased state of the bowels Worms are often also found to have existed & that too in great numbers, where the general health has been apparently good. I well recollect the case of a child in North Milford who fell from a height & was taken up in a state of coma from the concussion. A dose of calomel was given him which brought away twenty or thirty large worms. The child had been healthy to all appearance previous to the accident. Some physicians go so far as to say that worms are necessary for the health of vigorous children that they are nature’s scavengers a natural provision to destroy the superabundance of food taken into the stomach. Dr Rush was of this opinion. The opinion supported by Dr [Parr] It is a fact beyond controversy that very healthy children have worms with out manifesting any symptoms of their presence until the supervention of some other disease causes them to make disturbance in the system. It is but seldom that they are the excit. cause of dis. The following are some of the ways in which worms are injurious to the system. They may be injurious from their number obstructing the bowels and consuming too much food. They are particularly hurtful by the irritation which they produce when the irritability of the bowels is excited by fever. They sometimes threaten suffocation by rising in the oesophagus & in one instance a single worm I have known to lie in the fold of a volvulus of the intestines so as completely to obstruct the passage 76 Linneus attributed the dysentery to a worm or insect [illegible] dysenterical [languis] the measles to a similar origin. Various authors the itch, sigler, petechiae lusitanus the syphilis martin the elephantiasis nyander, eruptive & contagious diseases in general lancissi, plague, remitting & intermitting fever considering miasm [it] being a collection of insects # some authors, toothache Dr [Adam] observes cancer itself is nothing more than an animalcule a worm or an insect. It would seem from such speculations, that a great part of the diseases which flesh is [illegible] to result from a superabundance of vitality and that as Good remarks in his [illegible] corruption is no longer the triumph of death over life, but of life in one form over life in another. Such fancies lead into the wildest speculations of equivocal generation & relinquish all principles & all limits in natural history. # Vide N.Y. Rep. about the year 1815 77 Symptoms of worms. Those children are most frequently troubled with worms whose powers of digestion are weak. The symptoms of the presence of worms in the alimentary canal are very equivocal, for they may all proceed from other causes. They are countenance pale or flushed sad and dejected livid around the eyes, eyes sunken eyelids swelled pupils dilated itchings in the nostrils, head ache after taking food, mouth water [illegible] filled with saliva, breath fetid, great thirst, grinding of the teeth in sleep, starting in sleep fainting vertigo, palpitation of the heart, irregular pulse & cold abdomen bowels flatulent costive or loose colic throbbing in the bowels severe from [illegible] the small [intestines & umbilicus] appetite irregular & craving loss of appetite pain in the stomach when empty, which is relieved by food urine increased or diminished turbid and milky, stools irregular, containing much mucus nausea & vomiting Sleepiness particularly after eating, bloated countenance swelled nose & upper lip, paleness of the lips, irritation about the mouth, rubbing the nose, itching at the anus irritation about the neck of the bladder dry & convulsive cough difficult respiration sense of suffocation paroxysms of suffocation body emaciated frequent flushings of fever with irregular pulse convulsions, epilepsy and partial palsy. Of course these are not all present at any one time Chorea catalepsy & epilepsy are produced sometimes, by worms Dry convulsive cough Diff respiration In addition to the other symptoms there may be these of irritation of the lungs producing cough also irritation of the brain [772] It will be impossible to class all the articles inasmuch as we do not certainly know the modus operandi of many articles which yet have sustained their reputation for [illegible] Much stress has been laid upon the operation of cathartics in evacuating the [illegible] which the worms generate by their irritation, just as irritation in the lungs produces [illegible]. But then the [mucus] although it forms [illegible] for them, an effect more than a cause, and the worms will make [mucus] enough for themselves Probably many caths act by their acrimony upon the worms themselves. Others by the violence of their operation dislodges them. “Aloes are beneficial in mild cases as a tonic when there is no excessive irritation. If there is excessive sensibility & irritability they are improper as they irritate the rectum they may be given by injection When there are symptoms of worms though no worms exist aloes are serviceable in the form of elxiir prop.” 77:a. IV. [general treatment] In the treatment of patients afflicted with worms two general objects seem to have been pursued both in popular practice & in that of physicians 1st to destroy & expel the worms themselves & 2d to obviate their effects upon the system & at the same time by the improvement of the general health of the patient, prevent their recurrence and increase This second indication will often coincide with the first, inasmuch as a diseased state of the body is the most favorable for the multiplation of worms Of those remedies which destroy or expel the worms themselves we have three kinds 1st those that expel them by strong cathartic operation 2nd those that act mechanically upon them 3d those that are prisoners to them. 1st Although strong & even violent purges may be used to drive out an accumulation of worms in the bowels yet they should not be often repeated as they would increase the weakness & irritability of the stomach & bowels to such a degree as to favour this increase. In general calomel will be the best cathartic inasmuch as it will tend to promote a flow of healthy bile & to restore healthy secretions. In Europe the gall of animals has been administered. One of the best forms for the administration of cathartics is that of alkoholic tincture, for the sake of the joint effect of the alcohol hence elixir proprietalis in teaspoonful doses & the tinct. “The bark of the button wood taken from the north side of the tree has been recommended. It is a nauseous bitter & a cathartic good” # “It is a question whether cowhage acts mechanically or whether it contains an acrid principle like that which exists in the nettle” # One of the remedies that I have most reliance on for ascaride in tinct [illegible]. Fill a bottle with the young inner bark fill the interstices with [prosp] spirit & give I to zfs night & morning It is an old remedy and better than tinct aloes It is tonic & deobstruent” Some of the acids to be narcotic, are more probably active merely by their pungency, odour etc. 77:b. of hickory bark or buds have been found very serviceable Podophyllum peltatum is much used but is probably not better than other cathartics. The best form would be that of a tincture 2 Mechanical remedies are not now used. Cut hair has been given cowhage though some doubt whether the operation of this is wholly mechanical. I have thought that the root of osmunda given in pieces acted mechanically The filings of tin, formerly were much employed as was also an amalgam of tin & mercury. There is a curious account in one of our journals of a man in Kentucky who took a pound of the amalgam & was unable to expel it from the bowels The mass lodged in a part of the intestines & could be felt externally It was very troublesome to him when riding. Oil has been given with the intent that it should fill the respiratory pores of the tape worms & thereby destroy its life. In Madame Nouffeurs recipe The supper of panada is intended to act mechanically by its bulk. 3d The remedies which destroy the worms seem generally to be narcotics All articles of this class however do not have this effect opium for instance. Particular animals are sensible only to particular narcotics as for instance swine are poisoned by stromonium while sheep eat it with impunity. The most valuable article of this class are the two species of spigelia s. [ma??ndica] & s. anthelmia A strange notion has existed about a little innocent [illegible] was considered as the narcotic agent Similar reasoning has been used with respect to denarcotising the opium Opium denarcotised would be not better than bread Spigelia zii in ¼ pt water to a child may be given in divided doses. It is better to give a cath. e.g. cal. or ruhb Spegelia from zfs to zf for an adult Sometimes but rarely it operates itself as a cathartic Sometimes convulsions are produced Our pink is bad because it is gathered by [illegible] packed in hogsheads & the rotten saved & the rest [illegible] The emigrants from St. [Illegible] brought what they called worm syrup which they said shd be given in the night because it affected the eyes S. [anth.] is [illegible] S. [illegible] about zi if S. anth. “Pink is given more especially for the [round worm] & sometimes for the tape worm” [illegible] [illegible] & [areca] [oleacea] zii to zfs “The French use the syrup of peach flowers & seeds They first give sulph either zi in [illegible] decoction male form & an injection of the same. They probably act by their prussic acid” 77:c. The former is the one commonly used in this country and in England It is called Carolina Pink. This is a most valuable article and is useful not only for its operation upon the worms but for its effects upon the system, in allaying the irritation which they occasion. I have prescribed it for a cough & other symptoms of irritation where I had no reason to suspect the existence of worms Then given for its effect upon the worm from half an ounce to two ounces should be given in decoction in the course of the night, accompanied with rhubarb or some other cathartic to drive the worm off while in a state of intoxication. It may be given in powder in a dose of from 10 to 20 grs The French W. Indies s. anthelmia is used & called wormgrass. It is a stronger article than ours The French use the article in form of a syrup & give a teaspoonful at a dose. Veratrum subadilla & helleborus [fetidis] belong to this class and have been given in doses of 2 to 6 grs for children In Europe the most famous article of this description has been the Felix mas Other articles of this class are camphor, prussic acid & tobacco The bark of the cabbage tree (of which there are two species vide Good) is found highly valuable in this way by the West India physicians Other articles which have been said to be successful in cases of worms owe their success apparently to their acrimony in whole or in part, such as the terebinthinate oils Oil of turpentine is the one commonly Various aromatics have been used, as chenopodium [illegible], rue tansy “The leaves of cedar juniper & [illegible] powdered 20 grs They are acrid stimulating and tonic & may have a mechanical action. It might be used to add to the powdered leaves some aromatic as rue ol. tansy [worm] wood etc.” “Melia [azidurach] bark of root or plant zfi to zi act as emetic cathartic & narcotic. Acts more effectually at the south where the recent article is used” 77:d. employed should be given in large doses, when it will prove cathartic. A concentrated solution of salt has been strongly recommended given by the mouth or by injection Ether is much used by the French & perhaps has an effect upon the worms. Some of the other antispasmodics which have been popular may also have some effect upon them such as asafoetida, petroleum the essential oil of the chenopodium etc. Perhaps arsenic poison intestinal worms I have known it cure. Ammonia may perhaps act on them 2 Of the remedies which are designed to have an effect upon the system. In severe affections from worms our first attention must often be directed toward quieting the excessive irritation of the system, by antispasmodics. Various popular remedies for worms seem to have little other virtue The chenopodium anthelminticus & c. ambrosioides called worm seed & the c. botrys. or [juris] oak ar probably valuable, mainly if not entirely a nervine. They may be given in decoction or the essential oil may be used. The garlics are used in syrup or decoction they are nervine 7 have considerable effect as condiments upon the intestinal canal. The ictodes fetidus is of this class & so are the empyreumatic oils, petroleum given in a dose of 10 to 40 drops barbadoes tar etc. For giving tone to the digestive organs and exciting their sluggish action the tonics the bitters & the aromatics are indicated while mercurial [Artemesia] ][santonica] is no better probably than the other bitter tonics Some confusion results from the appellation worm seed being applied both to this and to [illegible] botrys c. anthel. & “Indeed anything which tends to [procure] healthy secretions of the viscera. Of this kind are the mercurial which produce healthy bile which is especially [illegible] to [illegible]” # “Indian corn or maize has been supposed to favour the generation of worms in the body. The aborigines of this country have been peculiarly subject to them perhaps from this cause” Worms are far less common now as are also colic dysentery et. than formerly when cold water & cider were drunk instead of tea and coffee AT the south likewise the negroes who feed more upon crude and raw articles are more subject [illegible] of the plantations it is a rule to give a decoction of melia to the black children once in 3 months # Though you can cure worms generally by calomel yet sometimes they will resist all treatment Eupatrium perfoliatum is used for worms Flowers of [zinc] are antispasmodic so also sulph zinc Dr Rush thought well of [sugar] especially when given in the morning Petroleum seems to be a valuable article a substitute for turpentine It may be supposed dangerous, but I have used it for many years without inconvenience I began with small quantities from fear of danger, but now I give 10 30 or 60 grs It very often to produce no violent effects. Yet we must not conclude hence that it is useless. Asafoetidae for instance produces nothing but a little [illegible] in healthy persons 77:e. preparations & other deobstruents will be valuable adjuvants. The metallic tonics as the preparations of iron & of zinc, the mineral acids, myrrh, bark, the various bitters & the astringents have been found useful I have used alum whey with advantage. Among us the geraniums & all the indigenous aromatics & bitters have been given in popular practice. Alcohol from its stimulating effect upon the digestive organs will be a useful vehicle, for the exhibition of medicines. Condiments used freely with the food, will answer to the same indication The diet of patient troubled with worms should be dry & stimulating, rather than liquid & cold raw fruit, acids cold water & all indigestible articles should be avoided & in extreme cases I would advise that neither food nor drink be taken but which has not been subjected to heat. I have apparently cured patients by this means. “[illegible] toasted bread [illegible] [illegible] vegetable [illegible] though they occasion [illegible] dyspepsia” A multitude of heterogeneous articles have been used as anthelmentics, besides those already mentioned; some of them are sugar; worm-wood; rue; peach flowers; bark’ of prunus virg; valeriana selequa used by the French; muriate of barytes; injections of mur. of tin (Alibert); oxide of tin grs iii with etr. of juniper (Alibert) mur. of amm. of linseed; mur. of amm. [illegible]I with jal. or rhub 10 gr.; all the forms of ammonia; crude mercury; merc. boiled in water; aethiops mineral; artemisia [illegible] [illegible] ([illegible] [illegible]) & a. [illegible] [illegible] [s?tonica] worm seed bitter & of some value; melia azedarach much used at the south; butternut bark intensely bitter dose a tablesp. full of decoct cathartic & said to be narcotic; allows asclepiadis I think I have seen the a. [illegible] then beneficial; etc. etc. Garlics seem to do well how it is difficult to say perhaps operate upon the worms. Garlic also will relieve the eruptions of worms. It is though also that garlic prevents worms I have a very good opinion of sulph ether introduced into the rectum used by the Germans, Italians nervine & antirritant. It is valuable both in cases for worms & in those of irritation & affections of liver severe pain in bowels etc.” ½ oz or 1 oz. iron filings taste by [illegible] remedy worse than disease Wherever leaves of [illegible] are recommended you may give our common juniper For the imported [illegible] loses its strength by keeping & drying Rosenstein recommends cold water during the operation of a cathartic He recommends effervescing mixtures to destroy the worms by carb. acid An old remedy of the tonic kind is alum whey Rx milk & water equal quantities & put in [illegible] [alum] to [illegible] give the whey [illegible] children takes it pretty freely; It is a given in cases of relaxation of bowels and for ascarides & round worm It is of consequence often to have a remedy [illegible] and not require to be forced down 77:f. Various external applications have been prescribed Oxgall & venice soap aa zi made into a liniment with oil of tansy or wormwood; Aloetic plaisters; ether oz vi, bruised garlic zi, camphor zi (used by the German Brera) for a liniment; petroleum mixed with gall; Most of the patent medicines for worms [illegible] or both contain calomel, Storr’s lozenges are calomel with sugar & gum. These are his white lozenges. His brown are resin of jalap, gum tragacanth & calomel. Good on the authority of the Germans recommends [illegible] milk Electricity A popular article (cath.?) is decoction of [plantanus] occidentalis strong bitter For ascarides I rely as much as any thing upon a saturated tincture of the juglans [illegible] & [illegible] All the indigenous bitters as cherry bark [illegible] melia [azedarach] zii of recent root is divided doses ½ pt water. When dried & long kept it is apt to disappoint here. It is acrid [as the] narcotic & cathartic a powerful article The berries are also narcotic causing lard to fall down not from [choking] as has been thought The [planters] think it too powerful for [white] children! Tape worms frequently produce headache [illegible] about the umbilicus yet generally produce a sense of weight. Yet I have known persons evacuate them when they had not been suspected Case of a man who had kept taking remedies for a catarrh Finally a medicine ? brought away to his own surprise and that of his physician a tapeworm Perhaps vomiting occurs oftener from tape worm than from any other species # “When the worms are very numerous, there is a sensation of something falling from side to side on a change of posture” 78 V. Symptoms of each of the kinds of worms with the treatment. 1st taenia solum. This worm generally inhabits the upper part of the intestines & adheres so firmly as to be removed with difficulty It is sometimes solitary but commonly in considerable numbers. When brought away from the bowels many of the joints are separate & have the appearance of gourd seeds hence the name. 2 T. lata or vulgaris This likewise inhabits the upper part of the intestines and is usually in families of three or four Both are called by the common name of tapeworm They may exist without any apparent symptoms of worms or they may give rise to the severest affections In general they are attended by severer pain in the bowels & more violent symptoms in general than the other worms. The diagnostic marks of their presence in great quantities, are sense of weight in the abdomen, # irritation of the stomach nausea & vomiting loss of appetite, irregular appetite weakness of the chylopoietic viscera, bloated countenance emaciation of the body etc. All these symptoms however may arise from mere irritation of the stomach of a child Adults are more generally affected with tape worms but children sometimes have them. For the taeina solum t. lata or vulgaris or cucurbitina the gourd seed worm the spirits of turpentine has been very successful. Though not prescribed by the physicians it has been used as a popular remedy here for more than T. lata fifty years. I have known a man of intemperate habits No cautions are given about the use of the article (so far as I know) But if it does not act as a cathartic immediately, it will produce great irritation especially of the urinary organs I recollect the case of a lady who had been treated with aph turp. in N.Y. taking 2 or 3 ounces Violent vomiting & catharsis had been produced and the tone of the stomach and bowels seemed to have been permanently destroyed Worry had indeed been brough away, but then they would come away themselves & the relieve was fallacious In delicate cases it had better be combined with castor or sweet oil In the case of the lady cath seemed to do no good, they would indeed bring away large quantities but they would return in a few days. I put her upon arsenic but she left town and I have not heard from her It is difficult to tell how arsenic operates whether upon the worms or producing healthy bile For the t. lata the spts turp. seems to do better 79 take a wine glass full of spirits of turpentine to expell a tape worm Though an habitual inebriate, he said he never had been so drunk in his life & large tape worm of this kind? came away # It is said sometimes to intoxicate & sometimes to produce irritation T. solum 2d The t. lata is the most difficult of all worms to manage. Spts of turpentine do no good at least in those cases in which I have tried the article In T. solum one case I gave zfs. In another I gave it in teaspoonful doses. In the latter it operates freely as a cathartic a single teaspoonful procuring as many as ten stools Worms were evacuated but they would make their appearance again in as large quantities as before. Indeed any medicine may bring them away for the bowels are sometimes so filled with them that they come away T. solum when the patient is walking, or is asleep. I have known two quarts to be brought away in a day, & then a fresh supply in a few days after! T. solum # Arsenic has succeeded better for this kind? with me than any other remedy, which I have used. In the case of a child 5 or 6 years of age who had both the round & the gourd seed worm the common cathartics were given with some advantage, as some worms were brought away; but the symptoms still continued and the worms passed occasionally with the stools. Fowler’s solution of arsenic was administered in doses of four drops three times a day. In a few days worms ceased to be evacuated the symptoms disappeared & the child has once had no recurrence of the worms [Osmunda] cinnamonea is bitter, subastringent and perhaps deobstruent. So is polypodium vulgare and perhaps more decidedly so The polypodium vulgare & felix mas They are used in chronic affections of the stomach & bowels & thought they have not obtained much reputation for worry in this country yet they have sustained their reputation for 2000 years. It was used by Galen “The [form] is tonic” 80 I recollect case of one patient, a woman, who kept passing tapeworms, in great quantities, for months. After failing with medicines I threw them all aside & tried diet All the food taken was roasted or boiled even the water used for drink was boiled. She was cured. It must be remembered the healthy bile & gastric fluid will destroy those worms & from this fact results an important indication, which I shall presently dwell upon. Felix mas the male form has been considered in Europe, as a specific for this worm. With us the osmunda cinnamonea [illegible] ([hog brake]) has been used as a substitute for it. It is bitter, astringent & sweet. The polypodium vulgare, which is tonic & deobstruent, & other forms may probably be used also The famous fern remedy bought by the king of France of Madame [Nouffleur] is as follows. Take a super of the following panada Rx water lbi [illegible] fresh butter z 2 or 3 bread cut into small pieces zii add salt zi & boil thoroughly. If the patient is costive give an injection of water lb is in the evening olive oil zii salt gr. s. The next morning eight or nine hours after the supper the specific is to be given viz. Felix mas ziii in powder, mixed with 4 to 6 z of the distilled water of the fern or the flowers of the linden tree the whole to be swallowed at a dose. In children the dose is reduced to zi of the fern Two hours after the fern is taken the patient is to swallow the following bolus R. cal. & scamm. aa grs xii Gamboge grs V powdered fine & made into a bolus to be given at one dose to a person of vigorous constitutiokn Ether acts especially upon the nervous system on which account it has been used as an anthelmintic Alibert for taenia gives about zi in a glass of the decoction of the male form in the [illegible] an hour after his doze zi of the ol. ricini are to be given in syrup or in composition the dose to be repeated twice & sometime three times a day The worm is usually evacuated after the first doses Mr [Bonadier] directs an injection of the decoction of the male form to which zii of ether are to be added Mat. Med. art. ether 81 Mathieu adds to Mad. Nouffleur’s remedy the filings of tine & the sulphate of potash The French & German add ether to the same remedy Rothier’s method is Rx powdered savin grs xx seeds of rue 15 cab. grs x oil of tansy gtts xii syrup of peach gr. s. make a bolus Take half in the morning & half after dinner, drinking with each dose a glass of vin. tincture of peach kernels Dr Baurdier gives the following Rx sulph. ether zi decoct felix mas 1 gill taken fasting 4 or 5 an injection of the same decoction with zfs of ether an hour after zii ol ricini or zi of the syrup of peach blossom the worm is discharged half organiz Oil is used in order to kill the tape worms by filling their respiratory foramina. Ol ricini has been given for taenia & other worms in doses of 3 or 4 z Liquid carb. amm. might be given for taenia The German physicians are fond of giving 3 or 4 ounces of castor oil They are fond likewise of peach flowers Within 5 or 6 years the bark of pomegranate has been recommended. Paris says bark of the root [illegible] probable however the office preparation is meant viz rind of the fruit which is the most astringent substance to the [illegible] which we have [illegible] also cathartic! I have not [illegible] N.B. The male form is astringent, and is given to enable the bowels by the tone it gives, to bear the [strong] cathartic afterwards. Hence the union of these give in [illegible] [illegible] may be useful I have seen the worm occasionally in rain water I recollection one man of 60 who informed me he had been troubled with then nearly all his life until he removed his [illegible] Change of place may effect a cure by change of water Probably [illegible] of our cholera are troubled with this worm delicate children only suffering much children troubled with them will be faint, have turns of colic etc. you will be called [illegible] Give an injection, and no worms will come [illegible] yet give afterwards a strong cath. & or repeat the injection and worms will come away proof that they were not in the rectum They probably breed in the duodenum I have known but one case in which they were vomited up. The subsequent cath. will bring away smaller worms More is done by diet int his worm than by any thing else Alcohol in this morning especially its bitter tinctures. Condiments are useful. Worms are less common now because condiments are more used. It is said that the aborigines when they cannot get salt used potash ashes by a condiment The aborigines are said to be very subject to worms # Ascarides sometimes produce severe pain at the umbilicus and colic # “Ascarides though often found in the rectum are generated in the stomach & small intestines. Hence they are sometimes no discharged till the second or third operation Hence they are sometimes thrown up by vomiting. I have examined this point carefully 82 3d Ascaris vermicularis. This worm is always troublesome when it exists in considerable numbers though it is but seldom that they exist in healthy persons in such numbers as to give rise to morbid symptoms. They are very common in children, and not rare in adults & are called by the generic name ascarides These worms are commonly found in the rectum & hence are often said to inhabit that part This is a mistake they multiply abundantly & lodge in the rectum as they daily pass void by sphincter. Sometimes they exist in the stomach in vast numbers (hence called maw worms) so as ever to threaten suffocation by rising in a ball into the esophagus & sometimes they cause severe griping pains by their presence in the small intestines # They pass in the stools & sometimes come away spontaneously at night, they are said even to make their way to the vagina & urethra of females producing troublesome symptoms X Ascarides are most troublesome in the latter part of the day & the first of the night, when they excite an intolerable itching at night [illegible] probably than feeding They give rise to symptoms of general irritation & sometimes to a cough # Ascarides are particularly injurious to dyspeptic patients & they themselves may give rise to the symptoms of severe dyspepsia such as craving appetite, indigestion, faintings. Flatulence, cold extremities pale & sallow countenance, cough etc. The irri “They are attended with violent itching about the rectum general irritation convulsions irregular appetite pale urine flatulence want of vigorous action of chylopoietic viscera increase of mucous secretion darting pains in the abdomen stomach & chest faintness cold extremities the symptoms of dyspepsia sporadic cough” Tobacco injections & tobacco smoke injected are very useful and will often cure. It is not safe for children I have seen great prostration produced in children & I have known an adult killed by a tobacco injection # A physician who had been much troubled with ascarides told me he had tried merc. oint. externally with advantage. “I have used it but was rather disappointed # When the ascarides are in the small intestines, tobacco smoke will do not good & by its debilitating effect will favour their existence “Injections of camphor and milk have done more to remove ascarides than all other remedies I have used. The injection immediately removes the irritation produced by the ascarides & the ascarides themselves. It may be made of milk ziv to spts camph. zi This is the form in which I have used it, probably an emulsion is as good, perhaps a better form” M. M. 83 which they cause sometimes, in children brings on convulsions Whenever, finally, they exist, in the alimentary canal they are accompanied with great quantities of mucus in this part. They feed on the mucus of the intestines, the flow of which they excite by punctuating the mucus membrane Treatment It is very difficult to cure a patient troubled with ascarides. The most immediate relief is given by injection. If the worms are in great quantities & too much “Tobacco smoke is one of the most powerful means we possess for the involved in mucus, they may be completely removed by cure of these troublesome worms” injecting tobacco smoke. Injections of warm water or milk & water will relieve for the time being by washing out the rectum & if a quantity of aloes zis to ½ pt is added a still better effect may be expected though camphor being a nervine & a poison to the worms would be a still better addition. Injections of milk and water, with camphor zii tinct camph to ½ pint, will if preserved [illegible] destroy them 15 grs of [illegible] [saladilla] have been injected. Still the frequent injection, required in bad cases may debilitate the bowels & consequently invite the return of the worms. For internal administration. I have found a tincture of the buds or bark of the hickory given in doses from a tea to a tablespoonful one of the best articles both for removing the worms & for preventing their return Drastic cathartics should not be depended upon for they weaken the bowels & increase their irritability & hence favour the production of the worms. On the contrary calomel & tonics should be given to restore healthy secretion Aloes if given should not be in large doses, for that will irritate the rectum still further, but in smaller ones as a tonic Oily articles shd be avoided as butter, because they relax the [illegible] of the intestines Potatoes, vegetables All kinds of pastry avoided All the metallic tonics are useful as tonics They are thought also to be unfriendly to the worms It is said that forth ascarides a pint or a quart of sea water has been drunk with advantage, producing vomiting & purging. Salt is a good remedy. Dr Rush proscribed a teaspoonful of salt in the morning to a gentler one much troubled with ascarides. He told him after trial than the remedy would not do. Dr Rush gave him, then, for worm powders # For the worm the [illegible] the pink shd be the remedy vide [illegible] “Rhub & cal. are the best cath. but all are useful For children Rx tinct. [illegible] Fowlers solut. cold water” “Common salt ground up with cochineal to colour & disguise the article. The gentleman reported that the last prescription had answered well. Dr Rush also believed in sugar. This more doubtful The asclepiasis have been much used especially for this worm especially A. incarnata called wild hemp It is dried pounded to a fine powder mixed with molasses & given in doses of a teaspoonful Or [illegible] down and make a strong decoction [illegible] the [illegible] with it molasses and give freely until it moves the bowels This much used by the practitioners of the state more than any other article after calomel. it is an article which may always be obtained growing in clayey situation and is safe The other asclepians are similar & may be used S syriaca is the most laxative 84 To prevent the return of ascarides, condiments should be freely used such as pepper, ginger etc. in short all warming and bitter things In extreme cases let the diet be so regulated that nothing shall be received into the stomach which as not been subjected to heat. Mercurial ointment has fasted in my hands. 4. Ascaris lumbricoides the long round worm is perhaps more commonly found in the alimentary canal than any other This worm more than any other is found to have existed in the stomach or intestines while the general health has been good is the presence of worms not suspected. Strong purges may be used to remove them & alcoholic tonic tinctures given to prevent their increasing. For this latter object the carbonic acid has been recommended in the London Med. & Phys. Journ. & in confirmation of the idea I have used soda water with advantage Melia azedorach or pride of India a decoction of the bark is much depended on at the south for their young negroes who are much subject to worms. It loses much of its virtue when dried. The spigelia is also sued but of this I shall speak under the head of general treatment. I recollect with an aff. of the liver wh often vomited up dark [gravous] blood, which had evidently been long in collecting. Finally he was said to have thrown at a snake. Many eyewitness testified to the snake & to its eyes & teeth. I saw it. It was a very large round worm of the kind To be distinguished only by the violence of the symptoms. The same itching at the arms will exist as of the ascarides, but non violent etc. “Treatment similar to that for ascarides. It is more common than is generally supposed. Many of disease & death by irritation from an unknown cause, are probably owing to this worm. In examination the contents of the bowels should be placed upon linen cloth and then this worm can be seen.” For the gordius Linnaeus recommended the angelica Archangelica (not our viz the [atropur????]) 85 5. The tricocephalus is but seldom met with The irritation produced it may be so great as even to bring on delirium & will be manifested by screaming throwing of the hands & [fat] etc. I have found this worm in a fold of the volvulus of the intestines vide Volvulus. I should try narcotics for this worm, but cannot speak from my own experience. I should recommend also an injection of a table spoonful of ether in a gill of water or mucilage. Ether given in this way will undoubtedly pass the valves of the intestines in a state of vapour Vesicular worms, according to the old division of verminous diseases, are met with commonly in the brains of adults & are attended with the symptoms of vertigo, convulsions apoplexy & hydrocephalus. Cases of worms & of colic are much less frequent with us than formerly; owing to the change in our mode o f living. They are said to be very common among the aborigines of this country One volvulus may be received within another a second, a third and fourth time & [illegible]. The whole may then become inflamed, the vessels may run from one to another, and the whole become one complete mass of organised matter or sometimes [illegible] “It may occur in any part of the intestines except the rectum though the colon is often received into the rectum” The symptoms of the two kinds [illegible] [illegible] owing to the different susceptibility of these two portions of the al. canal, and the diff. ages of the subjects of each Nor located in books vide Ed. med. & surg. J where the best account of it is given. Good merely mentions it as an accident that is found sometimes to have occurred in ileac passion “Predisposing of exciting causes” The cavity of the natural stricture may not be large than a goose quill, & such children will be very liable to an occurrence of volvulus This is not a primary disease. It occurs more in some families of [illegible] fibre & [illegible] phlegmatic temperament It may occur from debility of constitutional or that of the bowels [illegible] by bowel complaints etc. Local violence One instance, in here the child was apparently thrown into it by being carried over the shoulders 86 Volvulus or Introsusception This is a disease with which I was at first very much perplexed especially as I derived little satisfaction from the books Volvulus or introsusception is the reception of one portion of intestine within another. It doubtless exists often in a slight degree, when there is a strong action of the bowels & are inverted peristaltic motion & the bowels disengage themselves. Sometimes there is a double involution, or one involution within another. In some cases likewise the cavity of that portion of the intestine is entirely obliterated by the tumefaction of the coats. I have always found in post mortem examinations, that the upper portion of intestine was received into the lower & not vice versa the involution having been caused apparently by inverted peristaltic action This affection of the intestines occurs oftenest in children though adults are liable to it. It would seem also that some families of a leucophlegmatic temperament & delicate constitution are particularly liable. It may be caused by a natural stricture of a portion of the intestinal tube when it will be incurable It may arise from extreme irritability; local violence & injury may occasion it, & the irritation of worms may bring it on. Drastic cathartics may bring on volvulus & hence should be cautiously avoided where there is a liability to it. Bowel complaints, as colic, cholera, dysentery etc. sometimes terminate in one or more volvuli of the small intestines. The disease is more frequent in the summer, when debility is greater & bowel complaints prevail “Symptoms incessant irritation one or two copious evacuations but usually these have ceased entirely before the physician arrives constant efforts to vomit, resembling hicup constant efforts to pass stools & nothing passes but mucus streaked with blood Generally mistaken for hydrocephalus In bowels complaint of delicate children look out for volvulus It is much more common in some seasons than in others. About 10 years ago they were quite common. I had many letters from our students, who met with the disease & disagreed with the phys & gained [reputation]. They frequently sent me such accounts. Sometimes there will be a partial involution of the large intestines [illegible] to relaxation of inner membrane what descends like a funnel & may be felt by the finger # In the large intestines there is not very much irritation than is torpor of al. can. not much vomiting except upon the administration. There is no purging You may sometimes determine that of the large intestine by heaving the peristaltic action discard & stop at the [illegible] This is most common in adults. The symptoms are more mile # It occurs in females who have had long continued effetion of uterus, occurring in females about cessation of [catamen] and from long continued bowel complaints. The [inner] membrane will descend like a funnel An injection will perhaps 87 Symptoms These will be different according as the affection is of the small or of the large intestines 1st Where the small intestines have one or more volvuli the symptoms [illegible] vomiting or Symptoms like those of violent injury to abdomen vide case 1st 6.89 a constant endeavour to vomit as often as once in ten or fifteen minutes the matter thrown up being a greenish fluid or simply mucus. In severe cases the vomiting is attended with a discharge from the rectum at the same time. The stools are fecal at first & copious but afterward they are small in quantity & consist principally of white mucus streaked with blood the blood not being diffused throughout the mucus as “no fecal smell generally” in dysentery, but in streaks or specks. These symptoms are attended by others which indicate great inquietude or irritation such as throwing the h ands & feet, rolling the head paleness of coutenance This set of symptoms resemble those of hydrocephalus & hence volvulus is often mistaken for this disease. The pulse is small and frequent “[illegible] usually occurs in 24 or 36 hours” 2 A volvulus of the colon or rectum is not usually attended with much vomiting unless this is excited by cathartics. It is attended with the ordinary symptom of constipation. There is no evacuation from the bowels unless at times a little blood and mucus. If the passage be not completely closed, an enema thrown-up will remain & not come away if completely closed. it either cannot be thrown up or it returns immediately. Blood often follows the introduction of the pipe. Indeed the inflamed part is often so low as to be reached by the pipe & admit of being felt by the finger. come away immediately. [Schyl?la] of feces may come away And large quantities of mucus may come away sometimes ½ a pint. This is not apt to be fatal. Treat by a strong inject prescribe for the [illegible] with conium [illegible] etc. mechanical means The more cath. you give the more the unsolution is increased therefore give more Give mucilaginous injection, in involution of the small intestines, sufficient to fill the intestines. If it is said that the injection will not pass the valves. I answer that whether by sympathy or in whatever manner, I am satisfied of its utility # Give [illegible] enough to allay irritation I have treated # patients for 8 or 10 days without evacuation & cured them Not long since I had a case in what I suppose there was such a volvulus, for the attendants could not make the child receive injection. “thought the bowels were swelled” The child was suffered to get 8 or 10 days without evacuation & eventually died of another disease with which this was connected # In the incipient stages, filling the intestines with warm water [illegible] recovered. I was led to it from its [illegible] strang. hernia I am satisfied it acts well as a local nervine etc. I would recommend the injection of ether in cold water table sp. to a gill warm wat. will make it fly off. The inject of it is practised by the French & Germans. Other antispas. might be [injec??] is asaf. petroleum etc. 88 We may often hear a rumbling noise proceed as far as the stricture & then stop. Treatment The indications of cure are principally, to relieve the excessive irritation both constitutional & local & to attempt the restoration of the involved intestine chiefly by mechanical means When the small intestines are affected we must give opium and aromatics & depend mainly upon these as internal remedies, until the intestine restores itself. As an adjuvant the warm-bath will be valuable & fomentations or irritants, as mustard & horse radish leaves may be applied to the abdomen. Soothing injections also may be copiously given. The quantity of opium which will be safe at a dose may vary from half a drop to 30 None but the mildest cathartics are safe, as blue pill and aromatic tincture of rhubarb I have succeeded in giving only a decoction of senna & the blue pill [Savage] When volvulus is in the large intestines all our remedies must be given by injection. The warm bath etc. may be used & we may also attempt the restoration mechanically, by means of copious injection repeatedly given & thrown up with force Two cases are related of young men cured by inserting into the rectum & keeping these for a considerable time as spermacete candle with a quantity of opium at its extremity. The first case which I had I treated for constipation with repeated cathartics, which are thrown up etc. The attendants complained that they could not give the injections when I ordered I was ignorant of this case Tried warm bath & every remedy for colic constipation etc. Upon examination at first the colon was apparently wasting at the sigmoid flexure where there was a large tumour which we thought to be a malformation It proved to be a repeated & insolution of the intestines Inflammation had taken place & the whole was adherent, some [illegible] Afterwards I was called too late, to a similar case which upon an examination showed circular appearance Afterwards called in consultation to a child said to have hydrocephalus all the children of which family had died in a strange way. I pronounced the disease not hydroc. but some could not say what was the matter. No treatment was serviceable. Examin showed volv. of small intest. Symptom is above. vide p. 204 The children of the family were subject to diarrhoea & were leucophlegmatic. I afterwards [illegible] the family and was very cautious about cath. giving nothing stronger than blue pill or tinct. rhub. The family raised 5 or 6 children afterwards Case of a student [unaccountable] Dr Munson & Dr Smith at a loss. [Cath.] retained & yet not thrown off by vomiting Sitting by him I observed a rumbling noise Which he said upon my enquiry, he felt & which stopped. I felt the stricture. Spermacite candle, sharpened, opium at [end]. kept up about a [illegible] [renewed] afterwards injection passed up Case of a gentleman on the wharf similar cured 89 Cases. A man over whom a cart had passed without leaving any external injury, died with all the symptoms of volvulus of the small intestines. On dissection the duodenum was found cut entirely in two. One remarkable physiological fact occurred in this case; a cathartic was given by the mouth & produced a regular evacuation from the anus, although the intestine was completely severed. An interesting case occurred to me in which the worm ascaris tricocephalus was found to be the cause The worm lay in this fold of the intestine. Grace Linsey, a delict schoolgirl on was taken with slight in disposition for 3 or 4 days the rejected her food by vomiting then came on constipation with vomiting attended with great restlessness & throwing off the bed clothes, cold extremities, low & small pulse the tongue not much furred, little or no thirst, no tumefaction of the abdomen no determination to the head. She was visited on Tuesday and died on Saturday. A blue pill was given & followed by 15 or 20 grs. of calomel in divided doses No effect was produced though they were not rejected. Opium and stimulant were tried but were not retained. There is no pain but faintness & an uneasiness about the alvine & urinary passages. Both copious and small injection pass up well but produce no evacuation. On Wednesday injections produce stools which are clay coloured. Black vomit came on two days before death. P.m ex. liver very pale little bile in the gall bladder no marks of inflammation cavity containing the intestines very dry as in cholera. Two volvuli were found one in the ileum which was disengaged with difficulty, & one in the jejunum In other cases with similar symptoms I have had supposed there was volv. caused by worms, but have had no opportunity to examine Vide p. 204 [illegible] Lindsay’s case continued. After the examination we accidentally observed some of these worms minute & coiled up among the mucus on the cloths. The worms seem more calculated to irritate the bowel than any other “If it could have been known that the worm was there, perhaps tobacco should aught have succeeded # It is called leg ache in slight affections alluded to by DR Rush Affects the legs, calves of the legs [illegible] continues extends up to the [illegible] coats” It is a disease manageable in its commencement Being a severe disease it calls for decisive remedies The indications are to allay pain equalize excitement & promote peristaltic action by opium by diaphoretics by cath. Cal. in full doses some would call 5 grs a full dose some 10 But if 5 gr. should be given every hour it would amount to a full dose. You may give 10 gr. 2 or 3 times repeated. AT the same time apply warm bath & fomentations not regarding your giving cath. Put drafts at the feet. Follow the cal. with senna, salts etc. But do not be too anxious about the calomel’s operating immediately It is better that it shd lie sometimes in [illegible] vessels With the cal give opium also guiacum & guaicum with dovers powder the latter to act on the skin and the whole to produce a decided [nerve] action affect on the al. can. and on the whole system 89:a. Nervous Rheumatism Infantile neuralgia This is a disease which has never to my knowledge been described in the books, though it may have existed unnoticed I first met with it some years ago, but it is [not] some years since I have seen of a case. It may occur again It occurs in the winter and spring mouths & occurs after exposure to cold especially after the feet have been in snow water. Children are the only persons that I have known attacked # This disease is in its symptoms allied to neuralgia acuta. The affection leg ache is probably allied The attack is sudden after exposure to cold with excruciating pain in the inferior extremities sometimes rigidity of the whole muscular system more or less disorder of the digestive passages (apparently the muscular coat of the intestines is affected) abdomen frequently tense and full stomach sometimes irritable. If the disease advances there is nausea, vomiting, tumefaction of abdomen (appearance of tetanus?_ (coma?) etc. and the patient dies in 4 or 5 days The indications of treatment are to equalize excitement by acting upon the whole surface of the alimentary canal and skin at the same time introduce new action in the system commence with a full dose of calomel 5 to 10 grs or 20 & follow it by senna and manna, or castor oil and enemata “I do not expect that cal. [illegible] I as above will operate at 8 years therefore follow it. Immediately after administering the calomel I put the patient into the warm bath or the feet in to the tepid bath, wrapping them afterwards in flannel or boil cedar boughs in water, roll them in cloths and apply them to the body & feet. Irritants also may be applied to the extremities and to the abdomen Sometimes it will be best to repeat the cal in the course of 2 hours. The stools will be fetid and dark but this must not be considered as an indication for further evacuations as the appearance may be caused by the calomel, and is a sign that secretion is beginning to take place. After producing free evacuations by your cathartic you must keep up a regular course of exciting the secretion by cal. & guaicum with Dover’s powders, especially if pain continues & keep up a diaphoretic action by Dover’s powders calomel and camphor alternately increasing doses if necessary. Calomel and gum arabic, as an emulcent, & calomel and decoction of cedar twigs, as a diaphoretic may be given Give the calomel first in divided doses If cold applications are made to the extremities, to discuss the inflammation the disease is translated to the stomach and death is the consequence I called in the first stages, & am always successful in effecting a speedy cure The irritation of the system is so great that secretion is prevented hence the production of secretion I have been called to patients with [illegible] where little had been done the abdomen was swollen the patient went into a comatose state & died and that too where the disease was not of the most violent form After the bowels are thoroughly evacuated depend upon diaphoretics camphor guaiacum and [illegible] etc. giving so as not to offend the stomach and beginning gradually It is a violent and excessively painful disease and it is a great satisfaction to the phys. to cure it Dark stools [illegible], satisfied “The pain usually begins in the calf of the leg and extends to the contiguous parts. Sometimes it is attended with tetanic spasms & a constant rigidity of the abdominal muscles. The stomach becomes in these cases irritable, and nausea & vomiting prevail. In the progress of the disease the abdomen becomes full and tense, with constipation.” “It should be our leading object to make the muc. men. of al. can. & the cutaneous system active [concert] After the operation of cathartics, if the pain is severe give diaphoretics with opium, as Dover’s powders. Camphor & cal. in small doses as an alterative. If the stools are watery & fetid give opium ¼ gr. guaiacum 1 or 2 grs. camph. 1 gr. Ipecac ½ gr. with cal. repeated till some effect is produced not to salivate, but to this children are not so liable as adults” Young physicians are often called in a case of convulsions as their first case The neighbors & friends (women) have assembled in great numbers and their sympathies are excited. Hence an impression is made with respect to a young physician’s talents which will be of great service or detriment Morbid condition to brain so that ordinary stimuli produce convulsive action Convulsion fits may continue 5 m or from 1 to 2 hrs 90 Convulsions vide costiveness 12:a This is a very common disease of infants. The mortality from it is truly appalling nearly one seventh part of the whole number or deaths of patients under the age of puberty by the bills of mort. in Phil in 20 years Medical writers commonly make two kinds of convulsions idiopathic and symptomatic, the former arising from some morbid condition of the brain and nerves and the latter from some other disease, or from irritation. Children are subject to both kinds & most of the diseases of children may be expected when they prove mortal to terminate in convulsions The causes of symptomatic convulsions are as various as the agent capable of producing irritation though the causes of convulsions in one child will not necessarily produce them in another. The susceptibility to them varies with the age of the child and the peculiarity and degree of delicacy of the constitution. Convulsions may arise from the sudden suppression of evacuations to which the system has become habituated. Irritation from teething is a very common cause. Worms in the alimentary canal may excite convulsions. But perhaps the most frequent cause is the presence of indigestible substances in the primae viae. irritating the nerves of the stomach & through them those of the whole system. Over distention of the stomach, even with food of a healthy quality interrupt the progress of digestion & the food undergoing action [illegible] fermentation “Or the excessive quantity of food may produce convulsions from the mere stimulus of distention” “Dyspepsia is a cause” This is an important maxim in the first children of young mothers Their anxiety of mind will often affect their milk 91 in the stomach, becomes noxious matter & excites convulsions In the season of fruit we may always suspect this as a cause in children old enough to eat it. Calomel has been known to be so irritating to the system as to bring on convulsions Costiveness also is a cause of convulsions in children A change in the quality of the milk of the mother or nurse, produced by improper food or by strong affections of the mind, in some instances is the cause of convulsions in young children. Hence not only the diet of nurses should be regulated, but their minds kept tranquil. It may be observed also that the countenance of the mother or nurse as also those of the bystanders has more influence upon children than is commonly supposed. Even a child but 3 weeks old, will be strongly affected. In some families there is said to be an hereditary predisposition to convulsion among the children. For the treatment we have two indications 1st to remove the exciting cause where this is local & 2nd to relieve the irritation of the system 1st We must enquire into the causes with with care. If evacuations are found to have suddenly ceased they must be restored. The guns should be lanced. Anthelmintics should be given if there are worms If improper food is suspected we must be particular in our enquiries, or we may be misled by a [vague] & general answer. When the convulsions have been brought on by improper food or by food in large quantities recently taken the stomach should be evacuated by an emetic of 5 or 6 grs 4 to 8 of sulph of zinc or of ipecac. # How long should we wait after giving one cathartic before we try another? the child being in convulsions all the while? The equilization of temperature will do a great deal to remove convulsive action Besides the soothing of the [nerves] etrc. Some rely on one and [illegible] or another Oil of a amber is not in my opinion better than many others The oil of amber apparently is the [illegible] the oil of [capal] brought from its E. [illegible] It is recommended to dissolve the oxyg oil in [illegible] [but] it is slow of solution It dissolves readily in either 92 If the offending substances have probably passed the stomach & the irritation is in the bowels, these must be evacuated as speedily as possible giving and injection to begin with [illegible] it to [illegible] cathartic. Sometime it will perhaps be best to give a dose of calomel large enough as to operate both as an emetic & cathartic. Frequently large & repeated doses of cathartics will be needed in order to overcome the torpor produced by an excessive quantity of food. The food also diminishes the cathartic operation is the case with the French [dinner] pill. We may give calomel, 5 to 10 grs. or scammony 3 to 4 gr. jalap 2 to 3 gr. senna & manna, castor oil, neutral salts etc. If dry cathartics fail to produce the desired effect, the liquid should be tried. Sometimes will be acted on by one kind when they will not by the other # If one fails after 3 doses try another & assist with injections Begin with cal. & follow with the others 2. If the convulsions continue after the removal of the cause we must rely upon antispasmodics or even at the commencement. Of these the warm bath must be considered the most powerful remedy in convulsions of children always [illegible] & often efficacious. Its influence is immediate and extensive. Antispasmodics, as pearl ashes or aromatic herbs, may be put in to the water of the bath Of antispasmodic articles a great variety are used. Oil of amber Dr Rush called his sheet anchor in spasmodic diseases. It is useful internally, and applied as an external irritant along the spine. The artificial musk a preparation of amber is in my opinion a better article than amber itself, for all cases where amber is “# Seneca oil is more limpid & pure & approaches nearer to naphtha” Soot is a [illegible] Soot is efficient as a nervine tonic & deobstruent It is sometimes very efficacious in jaundice & dyspepsia It was very popular in Philadelphia with ashes for stomach complaints “The British oil is manufactured in this country from Barbadoes ter & spts turpentine” The nostrils may be rubbed & it may be given internally “also rubbed on the skin” Though so offensive to the small yet children taking the tinct readily potash [illegible] & [illegible] All the alkalies & alkaline earths are antispasmodic. They are not nervine properly. There yet seems to be abundant testimony to their antispasmodic properties. They are to a certain degree tonics. i.e. they have a specific action on the mucus membranes. I have maintained [illegible] they operated by generating excitability a view supported by Jobe vide Hufeland’s Journal in Lond. Med. & Phys. 93 indicated. The mineral oils from whatever source obtained, such as petroleum, seneca oil, British oil, are little inferior to the oil of amber I prefer the seneca oil 5 to 30 drops #. The eympreumatic oils are useful antispasmodic and soot is often given by nurses in decoction Ammoniae in any form is a good antispasmodic A solution of ammonia in spirits often contains an empyreumatic oil of this solution we may give to a child from 2 to 6 drops in an ounce of water. Either the spirt, the carbonate or the aqua ammoniae will be useful in alleviating spasms in children either applied to the nostrils, rubbed upon the skin or given internally. Dippel’s animal oil, a very fetid substance distilled from bones in a state of putrefaction owes to antispasmodic virtue to the presence of ammonia. It is too disgusting Castor and valerian are good articles of this class, but in cases of children they are too bulky & a sufficient quantity cannot be introduced into the stomach. A more powerful article than these is the asafoetida fetid gum 10 or 20 40 drops of the tincture. This is a very valuable remedy to give by injection using for this purpose either the tincture zii or a decoction all the alkalies are antispasmodic & are proper for children. The most powerful is pearlash given by injection, zi to zii in lbis of water I have seen more sudden and permanent effects in cases of spasm produced by injection of this kind, than by any other remedy. It has been successful in cases both of In for [illegible] who have [resumed] in convulsion 2 or 3 days when a variety of narcotics had been given. I have seen surprising effects produced by the injection These applications sometimes fail & we cannot tell to what sort of cases they are Yet we must have a variety of resources if we would be able practitioners Opium is powerful, but though it frequently relieves, yet it sometimes aggravates the symptoms I have given it with great success in paroxysmal convulsions anticipating the paroxysms yet in these it will sometimes fail 94 infants and of adults. Sometimes however this remedy fails & I am not able to point out in what particular “We are compelled sometime to practice [illegible]” instances it is indicated. All the narcotics are antispasmodic. Opium is a powerful antispasmodic and may be given to patients of any age when the condition of the system does not contraindicate it vid. lect on m. m I have given opium where the convulsions were violent & returned at stated periods with fever preceding. When the convulsions appear at regular intervals, as once in an hour, or day, opium in repeated doses may be considered a specific. Counter irritation may be valuable adjuvant in the treatment of convulsions. Oil of [origanum] & similar articles may be rubbed along the spine drafts may be applied to the feet and wrists & mustard horse radish leaves etc. to the abdomen. When the convulsions are frequently repeated in children and become in any degree periodical, a cathartic of calomel given once or twice a week, rarely fails to prevent their recurrence. If this fails I give stramonium or other narcotics If convulsions arise from organic affections we can expect to effect more than to palliate instead of curing the disease. “Counterirritation by mustard, horseradish etc. may be useful” An injection can do no harm can always be administered and if one cannot administer articles by the mouth Irritants may be applied immediately e.g. mustard horseradish garlic N.B. we do not need powerful vesication for the tender skin of infants. Even garlic sometimes vesicates Ammoniae to nostrils & in mouth Be sure that you have [water] enough to [illegible] the child completely for the nerves are apt to think that it is sufficient to half [illegible] child & then sprinkle or scatter water over producing an equal excitement Friction may be applied while in the bath & after coming out [illegible] with dry flannel If the irritants have been applied before the bath taken then off when [illegible] about to immerse in the bath & put them on again if necessary after coming out If the child seems to be in a state of asphyxia the emetic may not take effect; then irritate the fauces the child being lard on its abdomen supported by the hand of the nurse 95 When you are called to a child in convulsions, without previous sickness, direct an injection to be immediately administered and the warm bath to be prepared. if the injection does not relieve, put the child in the warm bath previously adding pearl ash in proportion of zfs to a gall. of water. Let the child remain from 5 to 15 minutes taking it out when it begins to grow exhausted. When taken out of the bath let it be wrapped in flannel & put into a warm bed. Then apply irritants as mustard, horseradish garlic, or aqua ammonia to the abdomen feet and wrists Apply aqua ammonia to the nostrils and temples As soon as the child can swallow give a dose of calomel; If the countenance is pale or livid the cause may be suspected to be some offending matter in the stomach & an emetic ipecac not [illegible] generally should be given. We may often succeed in exciting vomiting by irritating the throat with the finger or a feather & this method should be tried when the patient cannot swallow & is known to have taken improper food or when it is desirable to hasten the operation of an emetic. The child will vomit with much more ease if it is held lying with its belly upon the nurses’ hand, which this supports the abdominal muscles If the child is much agitated at the sight of the water which it is to be immersed, let the tub be covered with a blanket & the patient gradually lowered into the water there will then be no difficulty 96 Epileptic fits are very frequent among children Epilepsy is defined by Good A “spasmodic agitation & distortion, chiefly of the muscles of the face; without sensation or consciousness; recurring at periods more or less regular.” One side is generally more affected than the opposite The limbs may be fixed and rigid with twitching of particular parts. The pupils may be contracted or dilated & the attack may be followed by coma. The attack may be abrupt and without warming or may be preceded by hilarity, or a giddiness or other unpleasant sensation. Sometimes there is what is called the Aura epileptica, a sort of formication, creeping up the body for which the ligature may be applied The fits may be kept up by the constant presence of the cause such as malformation of the brain etc. or, by habit & while in the former case the disease will be incurable, in the latter habit will be very difficult to break up. The causes of epilepsy may be, malformation of the brain tumours of the brain derangement of the system produced before birth by syphilis & rickets or the same causes as those which produce the rickets & in children oftener than after preventing the disease may also arise though more rarely from mere excessive irritability of the system, even’ without any exciting cause of irritation such as indigestible substances in the alimentary canal or suppressed evacuations Among children however epileptic fits are most commonly excited by teething, suppressed evacuations & the irritation of a morbid condition of the bowels or of In scrophulous children remedies for scrofula may be given. [illegible] rickets I have often found advantage from blisters behind the [ears] I have found the cath mode of treat successful for children within the year especially calomel In some cases the most powerful cathartics are required If there is acidity of the passages so that cal. seems to gripe much [illegible] chalk any quantity from 5 to 10 It is immaterial whether the action is chem. or certainly the effect is good The system being very irritable ordinary stimuli or rather a little more than ordinary brings on [illegible] Hence improper articles improper exertions of mind & body etc. Careful management & [illegible] 97 indigestible substances in them. The treatment of epilepsy must vary with the causes which produce it but does not differ materially in the case of children from that of convulsion fits In epilepsy from rickets I have used the cold bath with advantage. In children our attention in the treatment of epilepsy must more especially be directed to the alimentary canal. Cathartics are far more valuable with them than for adults. I have almost always succeeded by means of a course of mild cathartics & joined with one of tonics, such as the tonic solution & the different preparation of iron When called to an attack brought on by offending matter in the stomach and bowels, we should commence the treatment with a strong cathartic in order to thoroughly clear the alimentary canal calomel is the best article but if the bowels are loaded with mucus so that calomel fails to operate we may conjoin 1 or 2 gr. of gamboge & of scammony & 5 of jalap & this though powerful, will yet operate kindly. In the subsequent treatment calomel should be given 3 or 4 times a week; though if there is a deficiency of mucus in the bowels an abrasion as it were the blue pill will be preferable or chalk may be conjoined. Among infants most cases are curable by careful management, both of the physician of nurse The diet should be regulated with great care Generally however there is a morbid appetite, & a sub-[insanity] There is often a difficult, particular waywardness [illegible] like into [illegible] etc. In children more than a year old I have given stramonium so far as to dilate the pupils keeping the child under the operation of it I have not prescribed it to children under 2 yrs or 18 m. I recollect one case in which the convulsion begun to subside as soon as the pupils began to dilate I would not prescribe to [illegible] but to [all] symptoms e.g. tonics all the nat. ton. tinc irr. cap. lead I would give the lead where cathartics, from the excessive irritability of the al. can. aggravate all the symptoms Lead will produce a torpor or sub paresis contrary to this Narcotics also will meet this condition Opium will occasionally, but not generally Why it is we know not but the fact is that phys. do not depend on [illegible] ep. seems to cause a determination to the head 98 with regard to food. This subderangement of the mind manifests itself also in other ways by oddity of appearance gesture & action. A strange propensity for climbing for instance is met with & epileptic children will often be so active & so artful as to be very difficult to manage For more particular treatment see my lecture on m. medical articles stramonium & nit. silver [illegible] turpentine from 10 gtts to zi diluted stramonium, camphor, opium atropa belladonna & most of the more powerful narcotics Arsenic zinc is one of the best of the metallic tonics Actual cautery, [moxa] etc. have been highly extolled “In epilepsy caused by rickets or by the same causes as those which produce ricketts. I have used the cold bath with advantage” “Mercurials followed by mild cathartics [Seontod??] etc.” The child will be still breathing languidly The parents think it dead If you look at it carefully you will perceive as languid treating & looking at the eyes you will often perceive a little convulsive motions of the balls pulse not much disturbed The child continues a few [illegible] with paroxysm & comes out with a scream like an adult from nightmare Not dangerous In a few instances [somerset] Case adult patient [illegible] a chair stands fixed eyes fixed come out with a stare irritable & sub derangement for a few days Afterwards [somersets] “asleep once a sleep twice” Case a girl last year gather up [illegible] [somerset], even 50 times than cataleptic then exhausted This case changed from chorea to catalepsy Repeated bleedings did not change the emaciation etc. 99 Catalepsy This affection when it affects children, is called in poular language still convulsions. It is a very rare disease among adults, but among children I have met with several cases of it In catalepsy the muscles are universally or partially affected with a tonic spasm. The patient remains fixed in the position in which it happened to be when seized appears asleep, is insensible and scarcely breathes. The eyes are commonly fixed, but sometimes have a little motion. The paroxysm may terminate with common convulsions. The length of the paroxysms I have known vary from a few minutes to three hours & in some cases they are frequently repeated The disease arises from the same causes in general & requires the same treatment as epilepsy & convulsions. Cataleptic convulsions sometimes follow other convulsions & in some instances have been brought on by drastic cathartics In adults catalepsy is often followed by irritability & a degree of mental derangement. “Catalepsy arises from the same causes and requires the same treatment as epilepsy chiefly by cath. & antispasm. Sometimes children are affected with catalepsy without it being observed When I commenced practice I thought the notion of still convulsions a mere whim” Dancing before the [illegible] of St. Vitus Dance [illegible] 3 or 4 well persons Comes on gradually parents complain that their children are getting into bad habits Awkward motions The dis. is not benefit. by [illegible] I recollect a gentlem. 40 or 50 yrs told me he had chorea when a child & recollects perfectly the indignation, horror & disgust when so long as to be unable to speak [illegible] Hand carried not to the mouth Sometimes the motions finally become regular “The dancing master” feet blind [illegible] then hands then body then stop like a statue then begin one foot like a [falling] [illegible] 100 Chorea Sancti Viti This is a disease not to be mistaken in its ordinary appearance the voluntary muscles are but partially subject to the well and their motion is convulsive. It occurs oftenest in females of relaxed habit & about the age of puberty especially if they have grown rapidly or been much confined to the needle or to study. In children this disease is often caused by irritation in the primae viae Chorea also arises in some cases from a peculiar irritability of the system in which ordinary stimuli produce convulsive action This irritability may be accompanied with relaxation, or with increased action together with a determination to the head. Indeed it is said sometimes to be connected with inflammation of the brain & hydrocephalus. With those who are predisposed to this disease, particularly if they are females about the age of puberty affections of the mind may bring it or epilepsy sometimes runs into chorea, or alternates with it. Finally, the disease may come on in a very gradual manner, so as not to be suspected, causing a strangeness in the gestures walk etc. which at first is attributed by the friends to the formation of bad habits. This disease is rarely fatal and is not difficult to cure in patients under the age of puberty after that period it is seldom cured. When the disease is of long continuance a great variety of remedies are generally “When I give cathartics in chorea it is not for the evacuation but to produce a new action. All cath. will not act favorably. Hamilton’s views in prescribing cath. are not generally correct.” There sometimes irritation of al. can. from accumulation of feces about the coecum. Hence Hamilton’s plan of purgatives Purgatives will cure but [general] by impression on system It is said to arise from a tonic infl. of brain I have read periodicals have not so I have seen all kinds of treatment tonics, cath narcot. electric. galvan. cold bath etc. etc. Perhaps no disease prescribed for more [illegible] periodically We find one and another article fails and are obliged to go the whole [illegible] off [illegible] narcotic etc. # “In one case of chorea I tried the arnica until the head became affected. The patient began with a decoction of zii the flowers & increased to zfs without any abatement of the disease” Prof T’s [illegible] [illegible] Nux vomica has been used with success in many cases but there are other narcotics which act more powerfully & more certainly I have not used it deterred by [Ba??] [Surrey] who found it injurious for some convulsive cases “Stramonium succeeded in a case following epilepsy” 101 tried and the one last given is apt to be considered as having effected the cure; but I am inclined to think that in many of these cases the disease instead of being cut short by the treatment and run its course and then ceased of itself The most common indications are [for] narcotics and tonics with antispasmodics as palliatives & permanent counterirritation along the spine in some cases. In children however cathartics are commonly indicated; though in general the plan of treating chorea by cathartics, has not succeeded very well in my practice. Dr Hamilton however depended upon cathartics and had better success, though it may be remarked that those who act on that treatment are also the metallic [illegible] When there are symptoms are symptoms of worms, of hydrocephalus, or of inflammation, of the brain or when the disease follows epilepsy we must treat as for those diseases; & if it the chorea is the result exclusively of the peculiar irritability above alluded to, narcotics must be our chief dependance. The principal articles which I have employed in my practice are conium, conium & iron sulphate of zinc, sulphate of iron & other metallic tonics. Various narcotics are used, as the nux vomica in doses of 1 or 2 grs of the seed in pill or 15 or 20 drops of the alcoholic tincture; and antispasmodics as valerian musk etc. may be used as palliatives Cullen’s favorite tonic was the ammoniuret of copper 1 to 4 gr. I have lately used it with advantage in pill 2-3 hours in creasing other tonics are mineral acids, nitrate of silver, bark & the arnica montana #, which is a narcotic & tonic & was successfully used by Dr [Monsen] in chorea” Dr. T’s copy [M. ?] “Sulph zinc 1 gr. may be given 3 or 4 times a day nit. sil. 1/6 to ¼ gr. succeeds best in relaxation of the blood-vessels” “Evacuate the first passages and restore the healthy secretions & irritability of the system by tonics & antispasmodic “I have rarely effected a cure by cathartics though I generally begin with them The cure with antisp. & tonic is slow 2-3 [illegible] with narcotics more speedy but uncertain” A good deal may depend upon the careful management of the patient keeping him quiet & amusing him especially avoiding the irritation of the [pressure] and the impertinent curiosity of strangers The young man in a debilitated “So camphor has sometimes been given in mania to such an extend as to produce epilepsy & sub-apoplexy & this sometimes cures the mania” 103 double the quantity, when the head began to be affected still there was no considerable relief The patient was finally cured by taking the bark in substance zi a day. One case which came on in the gradual manner above described & was brought to a high degree by a dysentery proceeded so far at least as to present the peculiar symptoms of hydrophobia such as horror of water etc. convulsives perfectly [like] that frothing of the mouth etc. died in coma exhausted narcotics tonics etc. no effect excitability exhausted by [illegible] This disease may affect the mind causing it to run upon particular subjects especially upon that of numbers & calculation. I once travelled a short time with a book pedlar who had the odd gestures of chorea & had also this facility in calculation, being in this respect fully equal to the famous [Serah] [Colbourn] [Serah] [Colbourn] though furnished in Europe with the best advantages for education never improved and this result I ventured to predict, when I first heard that he was to be educated. I have seen several such cases. # They have a peculiar articulation & expression of countenance; and are deficient in memory and judgment. Vide [illegible] 12 [illegible] for [Serah] [Colbourn] Case girl at stool good talents studied hard [stand] out of schools [illegible] Cal. narc. cath. tonics operated but [Elateri.] 1/16 gr. once 4 hr in about 24 hours deadly sick nausea prostration vom. purg. disease broken up. It may be diff. to class this A year after similar causes brought on a second attack # Connected with acidity gives great pain not dangerous “This is a troublesome and not unfrequent complaint, arising often from improper food and that stab of the stomach which causes acidity. In a torpid state of the stomach when the healthy action ceases or is feeble, chemical action commences, and the acetous or putrefactive fermentation, prevails according to the contents of the stomach” “If our remedy fails try another for there are no two exactly alike & the judicious physician will discriminate as they are indicated” Among the astringents should be mentioned the rose willow It is one of the pleasantest astringents & is a popular remedy in canker It seems to combine a mucilage Almost any of our wild willows may be used Nitrate of silver may be used It is often however difficult to touch the ulcers and we may then use astringent washes. Rhus glabra and R [typhina] are good astringents vide hosp. [illegible] sub. [illegible] The poison of R [vernex] I have more than once known communicated in more than one instances by using the wood as fuel. I recollect a man’s [illegible] to me on account of an eruption on his legs. I told him he was poisoned. He replied that there could be no cause for it but a pair of the pantaloons lately dyed black. Upon investigation I found that the poison species of sumack had been used by the dyer by mistake for the common one. Young persons are more 102 Cold bathing is sometimes advantageous tepid is seldom proper Electricity has been used. I have seen little benefit from it Setons, issues, tartartar emetic ointment along the spine & other modes of counterirritation, are employed & may be advantageous but where the irritability is great they do injury If the disease is not translatable it is made worse by counterirritation In the treatment of patients affected with this disease, we should bear in mind, that they are the subjects of great mental sensitiveness & irritability The presence of strangers in injurious & the remarks of bystanders upon the patient may cause an amount of mental irritation little suspected. I have succeeded in curing chorea by elaterium though this is an article not mentioned by writers as applicable to this disease. A young man debilitated by confinement as a clerk in N. York was thrown into convulsions and derangement of mind, by a sight of distress while on board the packet for this place Elaterium was given to prostrate the system & break up the habit. It was successful & this led to its employment in chorea. I have completely broken up the latter disease by an eighth of a grain of elaterium & this is the only case which I have broken up vide end of this article Case a female delicate 14 yrs of age had not menstruated had been treated with cathartics, epispasmodics and narcotics, which palliated the symptom. The patient then took arnica for 10 or 12 days beginning with moderate doses (zii to a pint of boiling water being given in 24 hours) & increasing to I have found [illegible] which however was Dr [Rush’s] favorite remedy in females about the cessation of the [illegible] useful Friction antispas. electricity etc. had merely palliated The case then [illegible] to indicate tonics [illegible] the other remedies had [illegible] effect or not recovery rapidly upon bark Sometimes connected with pneumonic affected or with [organic] eff. of the heart In some of these cases [illegible] of copper 1 to 3 gr. rarely more than 2 gr. nauseating article [illegible] in such cases more especially As the [disease] advances sometimes [illegilble] difficult [illegible] swallowing dark [tongue] # [illegible] of them the book pedlar and [Minot] [Sheri] [illegible] [illegible] Both these had this facility in [calculating] # At this time there was not excitability enough left to enable the elat. treat. El. shd not be cont. more than 103:a Ulceration of the mouth in children This is sometimes a troublesome complaint and one that does not readily yield to remedies. It is commonly called canker. The complaint consists of one or more ulcers, which commence with an inflamed point or with a white slough situated commonly near the frenum but sometimes extending over the whole inside of the mouth. The edges of the ulcers are inflamed & elevated & their surfaces excavated, as if they had been eaten out with caustic. The child drools much and nursing is evidently very painful to it. A febricula attends the first stage. The bowels are slow and digestion not vigorous indeed the complaint often arises from improper food and is connected with that state of the stomach which causes acidity Treatment. First excite action of the bowels by magnesia, if there is acidity, blue pill, if there is torpor, or calomel grii & chalk grvi. After this give tonics & astringents as Moseley’s tonic solution 3 to 12 2 to 10 gtts 4 to 6 brak compound tinct. vitriol 4 to 5 gtts & the vegetable astringents as geranium in a [ter] spoonful of water statici spriaea cornus etc. a little laudanum may be added For topical applications we may use the vegetable astringents just mentioned, catechu, kino etc. or the following which has been recommended as very efficacious RX sulph. cupri grs x, cort. peruv. zii acad. gum zi mellis et aquae aa zii make a soft paste to be applied to the ulcers with a pencil. A weak wash of corrosive sublimate may be used Sometimes a mild caustic is serviceable, as nitrate of silver A wash of opium or of opium & corr. sub. is sometimes the best viola pedata makes a valuable wash. Asclepias tuberosa is escharotic. [Post] [illegible] case affected by this poison than old. When young I have often been poisoned myself by boing near the plant merely. Now I can brush past it with impunity provided it does not touch my hands or face. Some persons are not affected at all. The uncertainty of its operation is the only reason why it is not used in medicine. Corrosive sublimate is a good application for the affection of the skin. Yet the disease is a specific one and must generate run through its regular course. A similar disease is produced by the oil of the shell? of the cashew nut Ulceration of the mouth continued “The disease sometimes attended with severe pains, as severe as in tooth ach in which case opium is serviceable. Case of an adult use veg. astring. copper, zinc, opium, nit. silv. & at last corros. sublimate. This last would not be safe in the case of children. Intense pain was produced, which was remedied by holding it in the mouth There was a profuse salivation but it soon ceased and the disease was entirely removed. The surface of the ulcer was destroyed by the sub. & the dis. being local this effected a cure # I have turned my attention particularly to the question whether cal. produces it. I have known the dis. to allow dysentery It was an old notion that cal. broke down the crasus of the blood and it produced a tendency to gangrene. But in the venereal wards of hospitals you will see patients with sloughs all over the mouths and yet no gangrene 104 Gangrene of the mouth This is not a primary disease but a termination of other diseases making its appearance soon after their abatement I have known it follow dysentery and other affections of the bowels, but not any disease in which the blood vessels have exhibited an inflammatory action. It seems to follow diseases of the nerves rather than of the vascular system Children are generally subject of it. This disease is sometimes accompanied with much pain & at others with none ordinarily with little or more. One of the first symptoms is a constant inclination in the child to pick some part of the mouth with the fingers where the gangrene first commences either the teeth gums, less or cheek That part becomes spongy & has a fungous appearance in the course of a few days discharges a [illegible] matter, has a livid appearance & finally becomes black and dry the adjoining parts of the face become tumefied and indurated and the disease continues until a considerable part of the face becomes completely [sphacelated] when the patient dies It may continue sphacelatal in [illegible] etc. the sphacelus being hard dry & black like a piece of leather This disease has been attributed to the use of calomel, but it is entirely unlike that produced by this article, and occurs also in cases where no calomel has been given. # In those cases where calomel has been freely given the disease is not so apt to occur vide case 4th I have known a similar affection occur in the leg of a child, & an irritative fever preceded by rheumatism. Commencing with a spongy and orange coloured spot which afterwards become hard & black, the gangrene livid purpled as though the blood had settled pulse small not much disturbance of the circ. syst. except that it was large # & Prof. Smith & myself could not get down much medicine and were obliged to [illegible] [illegible] with external applications We [illegible] injections and a great variety of external application blisters “When the disease appears with tumefaction I think leeches might be of service. This was called by Dr Smith congestive inflammation. In other cases of gangrene, leeches would not be of service It is not easy to [class] the operation of charcoal It has been called a tonic, but it does not much resemble peruv. bark and we do not gain much by classing it with it It seems to act by generating an excitability Charcoal shd be made of soft wood or of lamp black burned over again in crucible, as is sometimes done by the apothecaries 105 extended up the leg and the child above the knees on both sides died [illegible] No applications seemed to have any effect. The child was irritable & The disease under consideration is nearly allied to that called swelled tongue, but the latter oftener attacks quadrupeds The treatment should be stimulant & antiseptic. Acrids as capsicum may be used & the arum triphyllum accidentally has been known to cure. In one case which I shall relate charcoal appears to have effected the cure. Case 1st The first patient that I saw affected with gangrene of the mouth was an adult female who had the typhus fever. The gangrene commenced on the inside of the cheek & when I first visited the patient a portion of the cheek as large as a dollar had sloughed off out? Great part of the food taken into the mouth passed out at the hole in the cheek. The patient continued in this state for eight or ten days & then died The attending physicians informed me that she has received the ordinary treatment for typhus fever. Case 2nd The next patient affected in a similar manner was a girl seven years of age. Previous to the gangrenous affection she had had a most excruciating disease, which affected the knees legs and bowels I have called it nervous rheumatism & shall notice it in another place. For this she had taken large doses of purgatives 106 calomel & opium, with diaphoretics & tonics. In three or four days the pain ceased and the fever almost entirely disappeared. The guns presented no symptoms of salivation & there was no increase of saliva. In five or six days after the fever subsided the patient complained of severe pain situated in the right temple & extending down to the shoulder like that which had been in the extremities. This was removed by opium to complain of the teeth Soon after she began to work at the molar teeth of the upper jaw, on the right side, at the same time she had a cough which was accompanied with an expectoration of white viscid mucus, and the breath became very offensive, resembling the effluvia of an anatomical room where subjects have been kept a long time. The appetite was tolerable, however the patient took animal food, with relish, and the bowels were easily moved with a little rhubarb the patient world at the teeth until she had removed two of the molar teeth with her fingers, she still continued to pick at the gums. The cheek of the side affected became hard, swollen & red. In forty eight hours a black spot appeared in the centre of the swelling. This spot the patient immediately began to rub with her fingers & soon made a hole through her cheek. The gangrene continued to extend, for a week & at the end of that period had proceeded as far back as the angle of the jaw affected the throat & perhaps the aesophagus The patient then died, having taken food and medicine will until within forty eight hours of her death. 107 Peruvian and oak bark, opium & camphor were very freely given the affected side of the mouth between the teeth & the cheek was filled with superfine bark & poultices of bark were applied to the face In the last stage affected perhaps the lungs Case 3rd Another case occurred in [illegible] subject a child etc. A female child, about 5 years of age was attacked, in the winter of 1813 with “constipation with fever” the complaint being principally confined to the bowels The attending physician gave a dose of calomel and worked it off with senna and manna. A considerable quantity of matter was discharged from the bowels, but from its appearance further evacuations were deemed necessary, and several doses of castor oil were given. On the fourth day I was invited to see the patient. I found her with considerable fever of the typhoid grade, attended with pain in the bowels and head. There was also some swelling of one cheek & the child complained of one or two of the double teeth of the upper jaw on that side. These she frequently attempted to pull out with her fingers & finally succeeded in extracting one of them The cheek afterwards became swollen, inflamed, and hard to the touch & in a short time an orange coloured spot, appeared, upon the outside near the centre, which soon became livid, and the gangrene spreading rapidly, the child died, in eight days from my first visit. She became delirious previously to the cheek becoming livid & afterwards, was comatose. In this case the disease seemed to affect the brain as it does in some cases Bark, opium and camphor were truly given & antiseptic 108 poultice applied to the face as bark [illegible] [fermenting] [poultice] Prof. Smith saw this patient soon after my first visit & agreed with me in the opinion that the case would terminate fatally. He informed me that he had seen but one case of the kind before & that he had attributed that case to an injudicious use of calomel After seeing this patient however, he considered his former opinion as incorrect since in this case there were no marks of the effects of calomel & there was no probability that the single dose of calomel, given in the commencement of the illness, could have produced such an effect, especially when repeated doses of other cathartics, had subsequently been given & had operated freely 4th Case. The next case which I met with was that of a female 12 or 13 years of age, who had the dysentery, in the summer of 1815, accompanied with much typhoid fever & rather a larger discharge of blood by stool than is common in dysentery. The child had been sick for some days before a physician was called. I did not succeed in my attempts to determine the diseased action from the bowels to the surface by diaphoretics & the warm bath, & the disease ran its course and nearly exhausted the patient When it began to decline, the stools to present a fecal appearance & the appetite to return, the friends were There had been some aphthae and I was on a careful watch 109 much encouraged I, however, began to expect a fatal result for I observed, between the anterior incisors of the lower jaw, a fungous enlargement of the gum, the apex of merely a slight discoloration [illegible] & swollen between two teeth which had a purplish appearance somewhat as appears in salivation sometimes. I apprehended gangrene in the case (perhaps from the countenance) and on the first symptoms of it informed the parents, who however, could see nothing alarming in the small swelling between two of the front teeth. I began early with oak & peruvian bark, and at the same time gave freely of brandy and porter. As this course had no effect I applied bark and diluted sulphuric acid to the part affected & also covered with the lunar caustic. Still the treatment had no good effect the gangrene extended under lip and chin became black and the child died Case 5th A child about 3 yrs of age cousin of the previous one [illegible] had a dysentery, in the summer of 1815 [illegible] as there was another member of the family sick in oil uncommon & interesting manner viz the case of chorea resembling hydrophobia was much neglected Her fever was typhoid & the stools sometimes bloody and sometimes of a green mucus. After a course of 15 days and amendment in the symptoms took place the stools became less bloody, the green stools more rare & though the patient was extremely weak but no reduced low as the previous one, the appetite returne After convalescing gradually for six or eight days, there came on a samous discharge from the nose, small in quantity but very fetid which reminded me of gangrene # In this case I examined the gums to see if there was any appearance of salivation and found the gums etc. Two teeth and a piece of the alveolar process came out The disease did not spread so rapidly as the other ones In addition to bark, tonic solution etc. I gave charcoal 110 of the mouth which I had not been on the look out for AT this period the patient inclined to keep her fingers I her mouth. # The gums were very clear and bright & adhered firmly to the teeth, except on the left side of the upper jaw, where the gums of the biscupides appeared discolored and discharged a samous matter. I declared the parents that in my opinion the case would terminate fatally. The child complained of pain in the face and teeth. The cheek opposite the teeth became swelled and hard and of an orange colour. I declared to the friends that mortification had taken place 7 pointed to a black spot on that cheek which happened however to be accidental. I was mistaken for the next day it was found that the black spot was produced by a piece of burnt apple skin, which was washed off This encouraged the friends; yet within 24 hours sphacelus took place the apple skin was in the very spot where I had supposed that I had seen it. This gangrene ceased to spread after the spot became as large as the end of the little finger A circular piece sloughed out and left a hole in through the cheek of about a quarter of an inch diameter The disease abated, the affected teeth and a piece of the alveolar process came away the lips of the wound produced by the sphacelus healed up & the child recovered I recommended the same treatment in this case as in the preceding, but having no confidence in it, & abandoned it and gave charcoal to the amount of perhaps a pound or a pound & a half a day I h ad pudding made of half charcoal & half flour, sweetened with molasses & sugar & fed to the child for the appetite was good. Tonic solution When the disease commences of itself # At the time when the disease called the scalled tongue was very prevalent affecting cattle principally with swelling of the tongue & salivation but to some extent human beings with swelling of tongue cheeks etc. It was found that acrids as [arum] were the best remedies pulse 120 tongue then [brown] fur, considerable pain 111 and compd tinct. vitr. were also given & I commenced the treatment with white oak & peruvian barks & yeast poultice. I attribute the cure, however, to charcoal. Case 6th This was an idiopathic affection. Martha Denison a delicate constitution about 12 yrs of age was attacked in 1819 with symptoms of gangrene of the mouth. There was severe pain in the teeth and jaws oppression at the stomach and symptoms of fever. I discovered the purplish spot in the cheek & “the gums soon put on a spongy appearance” In this case I commenced the treatment with an emetic, which operated favorably I gave it to [illegible] the excitability of the system & gave relief. I then gave stimulants, bark, brandy & opium & kept in the mouth between the gums and cheek a paste made of powdered bark wet with brandy and laudanum. The patient recovered, but the two front teeth of the lower jaw became very loose and there was occasional pain & suppuration for nearly a year. It was about a year before the teeth became firm. [Superfine] bark was occasionally used. Case 7th In 1820 I visited a black child in the last stages of this complaint. At the time when I saw it, it could not swallow. It lived however in this situation for several days I have seen several children in the latter stages Even if there is no chance for a cure it si desirable to be able to give a correct prognosis Trouble has sometimes arisen from the opinion that such cases were produced by calomel A student of this school in [Litch.] cty from notes of my lectures It is known by an [illegible] swelling in the throat some fever etc. etc. In some seasons it prevails extensively & affects persons of all ages. In some seasons these diseases which are called contagious affects one description of persons in another another owing to mode of life etc. “It rarely affects a person the second time. It is said that if it affects the parotid of one side only it may occur again” I have treated cases of this disease with great anxiety. I have never known cases of greater irritation than from this disease “It is milder in children than in adults & is seldom translated to the mammae or testicles till after puberty” “Sometimes the swelling of the testicle is simultaneous with that of the parotid gland or [previous] I have seen several such cases” “The first symptom observed is sometimes a soreness of the testicles. They at length become 4 or 6 times their natural size a suspensory bandage will be necessary” “In some cases there arises suddenly, [illegible] pain in the head pulse full and tense eyes red & all symptoms of phrenitis” 112 Cynanche parotidea Mumps This disease is an inflammation of the parotid glands & is generally moderate in its symptoms Sometimes however it is translated to other parts & is then a severe disease endangering life. It is milder in youth than in adults & in general it is only after the age of puberty that it is translated. The parts to which it is translated occasionally, are the testicles & the prostate gland in males the mammae of females more rarely & sometimes the brain or stomach I have never myself seen a case in which the inflammation was transferred to the mammae but do not doubt the fact Sometimes it appears first in the testicle or at least simultaneously in that & the gland This disease has been considered contagious In my opinion it is not, but on the contrary is liable to be epidemic. When its prevailed in college, the students who left in order to avoid the contagion were attacked as early and is certainly as those who remained. I have noticed that it made its appearance pretty regularly once in seven or fourteen years The fever which accompanies the severer forms is either of the inflammatory or the typhus grade or may be merely irritative & should be treated accordingly When the testicles are affected they are painful swollen sometimes to an excessive degree & sometimes so highly inflamed as to indicate venesection When the stomach is affected “it puts on crythomatic inflammation” and there is hiccough, subsultus tendinum, irritability of stomach and frequent vomiting. # When the brain is affected there is pain of the head & eyes, with hard and tense pulse When the parotid glands only are affected the # These symptoms may come on after the affect of test. [illegible] continued, some [illegible] begin to subside. Dr Rush observes that applying a blister directly on the infl. prevents the system from being affected. I do think blisters keep the aff. in one part “In some seasons an emetic at the commencement or a blister will prevent a translation” Having [learned] the importance of attempting the breaking up of diseases I cast about one year for means to interrupt it & found emetics quite efficacious Stramonium After the testicles have been affected some time and the affection begins to subside the symptoms sometimes change There is subsultus tendinum the stomach become affected vomiting is frequent with hiccough etc. In this case apply mustard to the stomach & feet etc. 113 a generally mild and more inconvenient than painful A translation makes it worse; more so when the translation is to the stomach than to the testicles & most of all when to the brain. Sometimes the complaint is very severe, the fever lasts three or four weeks and the patients are many years in recovering from the disease Treatment. The disease is often broken up by an emetic in the commencement It is best to stop it in the first stages if possible. Mild applications to the inflamed parotids we generally sufficient, such as ammonia or volatile liniment. Dr Rush however recommends blisters to the parts affected, in order to prevent a translation. When the disease effects the testicles & give emetics and apply discutients to the local affection. I also apply blisters to the inside of the thighs. They relieve the testicles when they are swollen & prevent translation to the stomach For a discutient was we may take the following Rx mur. amm. ziii; camph zi; brandy or vinegar 1 gill; water 3 gills. When the inflammatory action is high, bleeding may be practised. It will be well also to use a suspensory bandage. If the stomach is affected in the manner above described we have a difficult case to manage. Epispastics must be applied to the scrotum, counterirritants to the epigastrium to ally vomiting, with effervescing mixtures internally for the Ether is best given in effervescing mixture (carb amm. & lemon juice) Carbon ac. makes stimulants more diffusible & hence causes them to be [used] gratefully and often to be well borne when otherwise the would not be Case 18 grs plethoric parot. gland & testicles swollen head affected Relieved by bleeding decidedly entonic the only entonic case which occurred In the progress of his case stom. became very irritable abdomen sore & tender excessive irritability Did not recover his health completely for years was left dyspeptic & with nervous irritability. To correct irritability of stom. lem. juice [illegible] is most grateful add [doses] of aromatics lime water also external blistering etc. Tonics or metallic tonics myrrh asafoetida (nervine also) hops lettuce These cases are so obstinate and will give you an opportunity to try a great variety of remedies cajeput oil on sugar ol. valerian Though the cases may be apparently alike yet you may find one article best for one & another for [another] A very distressing hiccup, accompanied with spasms might have been mentioned in connection with the vomiting give ether lavender cajeput oil also & valerian which are called terebinthinates 114 same purpose diffusible stimuli as ether given to rouse the system opium ipecac, as tonic stimulant, diaphoretic & nervine 7 finally to allay irritation of the system in general antispasmodics as castor & counterirritants to the extremities effervescing mixtures absorbents, also, as chalk & magnesia, cathartics cantheride & occasionally emetics may be indicated. When the brain becomes affected, the lancet should be freely used, cupping, leeches & blisters, applied to the head of the neutral salt given as cathartics Antimonials nit. [illegible] cal. & neutral salts # Some cases will require a vigorous antiphlogistic course of treatment, others with typhoid fever will require in the [illegible] a stimulating & supporting one, while others again will have symptoms of irritation chiefly & require a corresponding treatment In the progress of the disease uniform perspiration will be valuable Angostura serpentaria, qualified with cardamom or cubebs The old writers recommend also [contrayerva] I have much used it atonics of a peculiar character resembles much agrimonia eupatoria which I have used for it in the country where it is easily obtained the latter is non astringent # “Cold to the head and warmth to the feet avoid mental irritation recovery is usually speedy adults most liable to this translation” I consider [quinsy] an affection of the mucus membranes and [tonsils] nearly allied to catarrhal aff. There is a catarrh aff. nearly allied in which there is a thickening of the membrane. This diathesis may also run into croup Good classes angina maligna with quinsy Here is the evil of nosology For scarlet fever gradually runs into quinsy. We must have science and nosology but still we ought to know the errors which nosology is apt to lend [illegible] & the imperfection of science I have the advantage of not [illegible] having seen the disease but of having had it myself often [illegible] with an unpleasant sensation a relaxation a disposition to hawk and throw off [illegible] In this stage it may certainly be cured After the symptoms comes on swelling, or moderately succeeding to this a chill then swelling with pain perhaps extending to the [illegible] The tonsils enlarge The fever is considered enteric or a common but unless among the labouring men in the country it is more usually subacute One tonsil is perhaps more enlarged than the other perhaps one goes on to suppurate & the other becomes of the natural size and appearance The uvula and fauces swell and respiration and deglutition are prevented. Sometimes ulcers from at first upon the tonsils. Examine each case and do not be too positive in calling it quinsy for this & scarlet fever do blend These symptoms continue 2 to 36 or 48 hours I do not know that I have ever seen a fatal case of 115 Cynanche Tonsillaris Quinsy This diseases has been called “I include also under the term quinsy all effections of the upper part of the aesophagus and pharynx which resemble quinsy in their grade of action” Quinsy is an inflammation seated in the larynx glottis & fauces The characteristic symptoms is swelling of the tonsils Sometimes it is seated lower down in the pharynx than the tonsils, but this does not alter the nature of the disease In some cases it is complicated with catarrh. Those who have once had this disease are very liable to a return of it “The disease common at the age of puberty that before or after” Quinsy may be divided into two stages 1st Predisposing debility indicated by relaxation of the uvula and tonsil, irritation about the fauces, weak deglutition, general languor, with cold chills and uncommon sensibility to cold. This usually continues from 3 or 4 to 12 hours the progress of the disease being sometime rapid and sometimes slow 2nd As the disease advances we find, soreness, pain, redness and swelling of one or both of the tonsils & an inflammation of the mucous membrane of the pharynx; deglutition in exceedingly difficult; there is a severe cough & especially a spasmodic one upon taking food or drink, there is much heat about the throat and about the head & sometimes pain in the head, with a pulse so full and tense as to indicate bleeding. Sometimes there is an excruciating pain in the ear. “rarely cough unless complicated with catarrh” This stage may continue three or four 3 to 7 days days. It terminates either in resolution, or suppuration. of quinsy though I have seen many that I thought would prove fatal. I have known a patient continue unable to swallow for 3 days and yet recover When however it is in the form of swelled tongue it may prove fatal. “An entonic fever may attend, with fullness of pulse much headache excruciating pain extending to the ear; but for more commonly at least in my practice, the pulse is little affected, and the disease is almost not entirely local” # riding on horseback and having the snow melt on his throat & [conduct] off the [caloric] rapidly # and shd carry a piece of alum in the pocket “It is important to distinguish this disease from roseola (scarlet fever) There is an erythema of the fauces distinct from both which yet may terminate in either [illegible] The diagnosis is generally easy but there are cases where it is extremely difficult & indeed there is no definite line believed the two especially in the first stages We must bear in mind that quinsy is commonly more inflammatory that it is not apt to ulcerate & we must be guided somewhat by the prescribing epidemic 116 The suppuration is generally in the tonsils, but in some cases where the disease is seated lower down, a part of the aesophagus suppurates. “The tonsils often remain permanently enlarged” Causes. Quinsy occurs must often in the latter part of autumn & in winter. It is caused like catarrh by alternations of heat and cold by exposure to cold & especially by exposure to cold storms of rain or snow. # Sometimes it is connected with dyspepsia & it may be brought on by irritating substances, as acids, acting upon the mucous membrane of the stomach. I recollect a case of a young man who was attacked with a severe quinsy in consequence of drinking freely of cider made cold with ice Persons who are subject to quinsy should be very cautious about exposing themselves to the alternative of heat and cold # Diagnosis. This disease has sometimes been mistaken for scarlet fever. It is not difficult however to discriminate between them by attending to their prominent symptoms the quinsy being as inflammation of the mucous membrane etc. The first stages however of scarlet fever, resemble those of quinsy, and the difficulty of discriminating between them is at that period much greater. In deciding upon any particular case we must be governed by somewhat by the nature of the prevailing epidemics Chewing camphor will also but not so well break up quinsy in the forming stage but chewing this article is apt to produce pleasant symptoms in the stomach and head Other stimulating applications would probably answer as [guaiacum] & any alcoholic tincture “The prophylactic plan of carrying alum in the pocket etc. has succeeded in hundreds of cases. Indeed when called in the latter stages I often tall them I can do little except to prevent it in future” When the dis is fully formed and when there is much pain in the neck running up into the [illegible] fomentations and the vapour of warm water, the steam bath by throwing over the patients head a blanket and having a teapot of warm water A blister also in the above circumstances will relieve the pain and give great relief An emetic also will be often very beneficial in the commencement of the second stage There is often an excessive quantity of acid in the stomach Case A young man in very hot weather [illegible] a large quantity of cider made very cold with ice was taken at night with great pain and difficulty of swallowing The patient was very anxious to be cured that night A large quantity of tartar emetic was given in excessive doses until a severe orgasm was produced then seeing to [illegible] stricture of the upper orifice of the stomach the [illegible] & secreted from every pore from the violence of the action of the system finally he [illegible] away, and continue in syncope for 10 or 15 mins came out of his fainting fit, the tart. ant. acted as a cath. and the patient was entirely relieved of the difficulty of swallowing [illegible] was merely feeble and exhausted from the prostration of the [tart] 117 Treatment In the first or forming stage. Quinsy may be easily broken up by keeping a small piece of alum say of the size of half a pea in the mouth, and swallowing the saliva until the symptoms have left. Various other astringents may be useful in the first stage. I have given the astringent barks and bitter roots, catechu etc. & have also combined with them the mineral acids chlorine etc. “But all these things will be injurious in the 2nd stage” When the disease if farther advanced a more energetic treatment is necessary. If the tonsils are largely swelled astringents will merely aggravate. IN this stage it may often be broken up by a strong impression made by nausea and vomiting. A strong emetic 3 grs tartar emetic with 8 grs of ipecac # may be given & when the disease arises from a chronic affection of the mucous membrane & acidity of the stomach, an emetic will remove it. In one case I gave half a grain of tartar emetic once in 15 min. until the system was affected, I succeeded in conquering the disease. The patient was in extreme pain & exhausted he fainted previous to fainting he was unable to swallow after coming to, he could swallow & the disease was removed. “But if the case has advanced a little farther, emetic will do no good”s Gargles will in general do harm rather than good, where there is much inflammation. If the irritability is extreme mucilages may be given, and when there is great difficulty in swallowing a cloth wet with spirit and water ay be applied over the mouth and nostrils. Cold water applied externally & internally has been recommended but is dangerous. It may be used however as a preventive. # Eupatorium etc. I have known some phys. generally successful [illegible] breaking up quinsy with cold water but as I predicted there was danger of the translation to the brain he lost one patient in this way “It may be used as a preventive” When the trails are much enlarged it is customary to bleed I would bleed it there was much fullness and strength of the pulse I have often bled and seen it done without the beast benefit still however without any injury as I could perceive “V. S. is important when there is danger of affection of the brain” Scarifying is generally practised. It is sometimes beneficial but often it increases the disease as is the case when a boil is scarifyed I do no t know that I can point out the circumstances which it is beneficial but if there is much irritation I think I would not scarify I have often had my own throat scarifyed without benefit Perhaps it is as often as once in 20 cases that the disease proceeds to suppuration. But if you puncture the swelling be careful to see where you introduce your lancet Case of [young] an opening was made which subsequently caused a troublesome sore the swelling burst of itself In various cases astringents was useful Lister’s [scoriae] (devils bit button snake root) it acts a little like seneka stimulating the fauces it operates considerably in a decoction It has been much used not of much consequence I have not much confidence in gargles The patient cannot gargle But you will give great relief by washing out the mouth with warm water or with mucilages or with a little old spirits and water which is very grateful to the patient Wash off the [illegible] which [illegible] Great advantage is derived from injecting with considerable force with a syringe & washing on the parts Spirits & water will be grateful & reviving 118 When there is redness and swelling but not extreme irritability, scarification is beneficial. If there is irritating soreness or inflammation scarifying will aggravate it After the inflammatory stage is past, blisters may be used I have not been successful in scarifying Bleeding may be necessary, if so it will be indicated by pain in the head and a full & tense pulse. When suppuration is about to take place poultice may be applied externally & vapor inhaled The latter remedy may be administered, very well in the following manner. Put a vessel of hot water in the bed, by the side of the patient & cover him with a sheet. # Touching the tonsils with nitrate of silver, is highly useful If the ear is affected, wet a piece of cotton with strong ammonia and apply it to the dear. it produces a pungent sensation and often gives relief The [liatris] scariosa is used in quinsy in the form of a decoction of the root. It is expectorant, diaphoretic & diuretic. It is called “devils bit” “After the inflammatory stage is established apply blisters” “If the irritability is extreme apply mucilages” “[illegible] & diaphoretics have been used in the early stages and are undoubtedly serviceable” # If you cannot well distinguish where suppuration has taken place, you had better not attempt to open the tonsils When the swelling is great poultices are very beneficial Dove’s [Dury] poultice Devils dung asafoetica Album graicum blown through a quill!! much used by my predecessors in this place Cathartics are proper early in the disease neutral salts if the fever if phlogistic Diet & regimen Give while the patient can drink, nitrous ether & water or a acidulated drink etc. Feed with arrow root etc. for the diet When the inability to swallow has continued sometimes the action is not enteric & the patient shd not be bled nor exhausted by cath. The disease is at this time principally local & from want of food etc. the pulse becomes feeble spirit and water injected into the throat will bring grateful and reviving [illegible] exhausted patient “Apply poultices keep the bowels open with enemata” “Inhale vapour of ether” Various gargles are recommended such as chlorine muriatic acid & water etc. but when there is much action they are apt to irritate Camphorated gargle vapour of camphor etc. There are a variety of these things which are mere palliatives The difficulty of swallowing is not caused so much by the swelling as by the soreness and pain for I have seen patients declare themselves much relieved and able to swallow when upon looking into the throat I could perceive no change in its appearance 119 “Scarification is recommended but I could never succeed with it. If the disease were pure inf. scarif. would be of service but it is an irritation infl. & scarific. increases the pain & infl.” In [illegible] case a free scarific. made the case worse in every respect” There is a stage when scarifying is beneficial when there is redness & swelling but not extreme irritability” “Leeches have been applied in the inflammatory stage externally and to the tonsils. It is difficult to make them take hold on the mucous membrane, but they would be more effectual there” “Suppuration does not take place in one tenth part of the cases. There is free secretion but no solution of continuity upon extermination” “When suppuration is likely to take place use poultices and inhalations of vapour poultices of bread and milk with stramonium are serviceable Gargle or syringe the mouth with spirits & water or camphor” “When the disease is seated farther down in the larynx it is essentially the same” “White dry pigeon’s dung in a poultice with bread and milk was used by Dr [Monson] He thought the phosphate of lime of service” I prescribed it in one case and they mistook for it devils dung (asafoetida) & it did wonders. I did not tell them of their mistake” [illegible] state of fever is a better classification than Good’s. Good separates the disease under different classes making one part are [illegible] disease another an aff. of the blood vessels “Scarlatina & angina are sometimes considered as separate diseases, but they seem to be only different forms of the same disease” 120 Scarlet Fever This disease has been called by various names, among medical writers, though the popular English appellation has been scarlet fever with little or no change. Canker rash however has been its common popular appellation in New England, until of late. Under the name scarlet fever I include both scarlatina mitis & S. maligna & likewise the paristhmitis maligna or ulcerated sore throat called also malignant sore throat & malignant quins. Other names that have been given are Scarlatina mitis & maligna cynanche maligna paristhmitis maligna scarlatina anginosa Enanthesis rosalia is defined by Good Rush a scarlet flush appearing about the second day on the face neck or fauces; spreading progressively over the body; and terminating about the seventh day; fever a typhus. This author divides rosalia into two varieties simples or mild scarlet fever which he considers as being slightly contagious & paristhmitica with an ulcerated throat & a rash not so regular as that of the other variety. This he calls highly contagious Under the name scarlet fever I included both the common mild scarlet fever with a rash & nothing more and the most malignant forms of ulcerated sore throat with the intermediate varieties considering them all as being but different degrees of the same disease This disease with its varieties a naturally associated with pneumonia quinsy influenza etc. Quinsy is an exception persons who have had it are more liable to another attack So too in tropical climates even have what is called a seasoning As a matter of fact this disease is theoretically considered contagious practically not so no precautions being taken the patient not being separated nor the friends and neighbors refraining from coming “The notion of contagion may sometimes be useful in keeping away idle visitors case in Guilford” 121 Scarlet fever often appears as a sporadic and sometimes as an epidemic disease. In general it affects children and women more than men. Dr. Rush’s opinion Some say that the disease never persons over 40 years of age. When epidemic however it attacks persons of all ages, though even then the majority of cases are among children and persons of delicate constitution. In general persons who have once had the scarlet fever are not attacked with it again, still this rule is liable to many exceptions for I have known repeated instances of a second appearance of the disease in the same person. This partial security from a second attack is met with in various epidemics & we may say in general that a person who has had any one of several different diseases the same general diathesis is less liable to have another Scarlet fever is said to be contagious especially in its severer forms The fact is disputed but this is the general opinion. Some fevers are perhaps contagion & among them some forms of this may be so. It certainly, however appears to follow the laws of epidemics and I am inclined to think that the facts which have led to the opinion that it is contagion are better explained by reference to those laws. It is said sometimes to go through the country like the influenza. Like other epidemics, those of scarlet fever exhibit appearances in different seasons, being sometimes milk and harmless & at others highly malignant & dangerous It has occasionally been as # And because blisters applied produced mortification It swept off whole families The fever considered a typhus It is not always so It is sometimes [sub-entonic] always however of a typhous grade 122 as the plague. About a century ago this disease prevailed in this state in its most malignant form, sweeping off whole families. It was called the black canker because the sloughs in the throat turned black & this name, though the influence of tradition, inspires terror in this town even to the present day Since that period the disease has probably been growing milder up to the present time. In 1794 however it was very severe in this town in Litchfield county & over the state more malignant than it has been since. Subsequently to that period adult males have been less affected. The last severe epidemic in this town was in 1803. Though sometimes attended with inflammatory symptom. Scarlet fever as a general rule, is of the typhoid or typhus grade & when malignant puts on the form of typhus gravior or gangrenous state of fever Symptoms. This disorder, when not malignant, nor irregular, commences with ordinary febrile symptoms general disturbance of the functions of the system, chills alternated with flashes of heat & pulse in most cases frequent and soft In severe attacks there is much nausea, sometimes vomiting, pain in the head back and limbs & great prostration The tongue of strength. In 1803 the disease frequently commenced with pain in the teeth or in the ear is the first symptoms In the progress of the disease there is more or less tendency in proportion to the violence of the disorder. In severe cases there is often great heat and dryness of the skin & perhaps the color mordax. In such cases also we frequently with an acrid discharge from the eyes & “When delirium is present it arises rather from inanition than repletion IT is accompanied with subsultus” Swelling of the tonsils is rather a favorable symptom Swelling and suppuration of the glands in the neck haemorrhage for the [illegible] & petechiae may occur 123 nose which excoriates the skin wherever it touches. Irritability of the stomach & vomiting are common & sometimes there is a troublesome diarrhoea. Petechiae may make their appearance. Case at [Hotchk??] town Haemorrhages sometimes take place; & in case of heat on the surface and what Armstrong calls congestive state of the system, a slight haemorrhage from the nose will be beneficial. Finally in the ordinary malignant forms of the disease the breath is very fetid. The epidemic of 1803 was characterised by great irritability of the stomach vomiting & diarrhoea pulse very low and feeble. In this epidemic after obviating the inverted action (of the stomach) stimulants were indicated. The throat is more or less affected from a slight redness to a deep slough. Sometimes there is a high degree of inflammation of the uvula & tonsils at others a relaxation indicating astringents both conditions accompanied with a high degree of tumefaction. A common appearance, in the commencement of the severe form of the disease is that of a white coat upon a part of the tonsils In the progress of scarlet fever, the affection of the throat may be more or less troublesome. It often terminates in ulceration & sometimes in gangrene In three or four days from the first appearance of febrile symptoms or rather on the second day of the fever the eruption appears in the form of a fine rash as described in the definition. In about as many days from its appearance about the seventh day of the disease it disappears Peculiar dulness of the eyes hollow sound of the voice patient appearing much like a night walker The first case of the kind which I saw I had no doubt about The friends had doubted whether he was sick enough to send for a phys. I declared at once that he probably would die. This was a case of pneumonia notha Most resembles measles Ordinarily distinguished readily sometimes with difficulty If scarlet fever is accompanied with a running of the discharges from nose with catarrhal symptoms, and is somewhat distinct in its eruption (hard under the touch under the skin) and such cases occur it cannot be distinguished from measles except by the general character of the epidemic I used to notice in the first commencement of my practice that on the first breaking out of the epidemic the older phys. used to wait and observe several cases before they decided upon the name 124 with branny scales & in ordinary cases the patient is then out of danger. The eruptions, however may vary much & even be altogether wanting the local morbid action being determined wholly to the throat. Ataxic cases will have no eruption. The worst cases of scarlet fever are those which transcend ordinary febrile action. In these the patient is scarcely sensible of being ill, appears dull and languid, his countenance indicates torpor of mind, he has little irritability of mind and is indifferent to surrounding object, his extremities are cold & his pulse small frequent and feeble & perhaps intermitting. Upon examining the throat ash coloured sloughs are found upon the tonsils and uvula. In these cases life is extinguished without any reaction of the system in the course of 24 or 48 hours, unless the tendency to death is obviated by the most powerful treatment. These ataxic cases resemble the ataxic cases of yellow fever pneumonia typhodes etc. which have sometimes been called walking cases The scarlet fever is liable to be confounded with measles, the disease which it most resembles. The marks of discrimination are these. In measles the eruption is less diffused is in pimples or circular dots more pointed & partly distinct & partly in clusters & the pimples produce a palpable roughness of the skin. In scarlet fever the eruption is diffused like erysipelas & consists of innumerable points or specks under the cuticle, intermixed with minute pupulae In some cases the eruption is in irregular patches & in others are uniform flush “Symptoms of pneumonia rarely attend scarlatina” This is one of a series of epidemics. It is usually followed or succeeded by measles & is followed by hooping cough For only it probably existed only as an epidemic now we meet with sporadic cases continually 125 while no roughness is felt, except in a slight degree upon the arm. The two diseases differ also in the time at which the eruption appears. In scarlet fever it shows itself upon the face and arms on the second day, but in measles it is not seen upon the arms till the fourth day. The scarlet fever is distinguished also by the absence of the catarrh, cough & determination to the lungs, suffusion of the eyes & the red and swollen state of the eyelids, which generally attend upon the measles. The latter disease also is generally accompanied by an inflammatory fever instead of the typhus which characterises the former. Still these two diseases of ten blend together so as to make the discrimination very difficult. It is barely possible that they are the same disease, though it may be objected to this view, that scarlet fever likewise is occasionally seen to blend with influenza # Epidemics of influenza are followed by [measles & scarlet] The prognosis in this disease will be obvious upon attending to the malignancy or the severity of the symptoms. In its severer forms it is always a dangerous disease & in its highest malignancy one of the most fatal while in its milder forms there is but little danger. # It is sometimes difficult to determine whether a particular case should be considered as one of scarlet fever, or of quinsy A case of scarlet fever in which there is no eruption & the tonsils are inflamed &swollen can be distinguished from one of quinsy only by attending to the state of the pulse, the prevailing epidemic etc. I have known it appear as an epidemic when it required nothing more than nursing One idea which I wish to impress particularly upon your mind, is that you must investigate the particular epidemic which you have to treat for no previous one will probably have been similar 126 The treatment of this disease must vary according to the diathesis. Epidemics of scarlet fever will differ widely in different seasons & different places & require very different treatment In a country where intermittent prevail the treatment will be different This has been some dispute about using the lancet in this disease. This will depend the degree of inflammatory diathesis. As a general rule emetics are indicated, but not always. Cathartics are generally improper but sometimes are required. In short indiscriminate treatment is as improper in this diseases as in any other. In this milder forms of scarlet fever, we may employ the usual treatment for typhoid fever, & administer those remedies which translate & keep up action and equalise excitement, as diaphoretics, the warm bath etc. For the mildest form it will be sufficient to give mild diaphoretics such as wine whey & elder flower tea, with perhaps a little antimony, acidulated drinks & gentle laxatives As the fever is generally of a typhoid or typhus grade, emetics are of especial importance in its treatment. They affect particularly the mucous membranes and may be repeated in the course of the disease, for the purpose of throwing off the accumulated mucus. The violence of the disease may often be completely broken by an emetic “In some epidemics when there is considerable action cath. of cal. are important especially in intermittent districts Rx cal. & jal. as for remittent bilious fever” “When there is tremor paleness, cold sweats, vomiting diarrhoea, cathartics might destroy the patient We must rouse the patient by counterirritants etc. and then we may go on with the treatment by emetics of ipecac etc. “Dr Rush bled but f.s. is very rarely indicated and in such cases as approach to A. tonsillaris” “Still it [illegible] all forms entonic atonic etc. “If malignant give bark & the min. acids. If the system does not respond give cantharides & capsicum oil of cinnamon cloves or cajeput” 127 at the commencement. All writers agree in recommending them. [Witherin] advises ipecac grs vi & tart. ant. gri for an adult followed by a strong decoction of senna Dr Rush recommends the turpenth mineral 2 to 6 grs with the view of strangling the disease in its birth. Sulphate of zinc is a good emetic & is preferable in the latter stage. It is local in its action & tonic in its effect. It operates speedily and produces less exhaustion. Vomiting by snake root has been practised In the irregular forms of scarlet fever, this practice is more questionable & if emetics are given they must be preceded by stimulants to rouse the powers of the system Cathartics are sometimes needed & calomel is to be preferred The judgment of the physician however must be exercised & the character of the epidemic studied, for great caution must be exercised that the system be not weakened by them & in extreme debility they should be preceded by stimulants. In some epidemics they will destroy the pat.” In some epidemics bleeding may be proper, but the apparent indications for it will generally be better answered by leeches about the throats and [temples] In malignant cases where the powers of life are very feeble no evacuations are to be used. External irritants are to be applied to rouse the system such as ginger mustard brandy a paste of mustard spts. turpentine & aqua ammoniae etc. Internal stimulants must be given Ammonia with bark opium etc.” “Tinct. canth 20 drops once in 2 hours till there is some effect.” “Serpentaria with ammonia acts as a tonic and diaphoretic” Where there is a prejudice against cold affusion with water alone spirits or [illegible] or camphor may be added 128 [illegible] to 4 [illegible] 3 or 4 such as capsicum Capsicum especially when the stomach is debilitated 4 to 5 grs [illegible] Cantharides in 20 drop doses. Ammonia camphor quinine, mineral acids etc. Carb. amm. & cantharides may be given to excite the system & be followed by bark and brandy to keep up the excitement. Diffusible stimulants also may be required, such as chloric or sulphuric ether 20 gtts to a teaspoonful of water for a child. In small children if there is difficulty in getting down medicines the bark may be given by injection, or the body covered with it, by means of a bark jacket. In severe cases, not of the most malignant form, the heat and dryness of the skin are often very great & calor mordax may exist. Cold applications to the skin, especially those of stimulating kind will then be beneficial. The cold bath cold affusion, or sponging with vinegar & water or spirits & water may be used according to circumstances. The cold bath or affusion of cold water may be superseded in case of prejudices on the part of the [illegible] or objections from other causes, may be superseded by sponging the body with vinegar & water If the case is attended with extreme debility and relaxation of the system or if any chills are present sponging must be used & [illegible] with caution. If the cold applications produce a chill or if the eruption comes out irregularly. I should advise the tepid bath to determine to the surface. In the advanced stages of the disease when debility & relaxation are great the vinegar & water should be made tepid & spirits may be added. The rules with respect to these applications are the same as in typhus. In the atonic form of “In children with disturbance of the stomach and pain in the bowels at the same time the eruption not coming out well use the tepid bath It obviates the tendency to convulsions and makes the disease regular In the most malignant forms it is inadmissible” “If there is irritability of the stomach give chloride [illegible] 4 grs 2-3 hours absorbents counterirritants” “In the latter stage of protracted cases emetics of sulphur zinc or copper are very useful” “Withering advises in the typhoid state, after evacuating the stomach & bowels to give senega freely This would be injurious in a malignant case” 129 scarlet fever, the cold bath or cold affusion must not be used IN 1803 I used sponging with vinegar and gave internal stimulants at the same time as min. ac. alc. brandy For children the tepid bath is invaluable in scarlitina particularly in the early stages of the disease and when the eruption is not fully out, or where the eruption is irregular. It is questionable however, how it would succeed in the most malignant form of the disease If there is great irritability of the stomach with vomiting, absorbents and counterirritants are to be used & in malignant cases capsicum, tinct. canth. & care to be given In cases of vomiting saffron & snakeroot If there is much diarrhoea we may give # white decoction with opium, injections of laudanum etc. astringents etc. In ordinary cases, when the eruption has been regular & ends with branny scales, about the seventh day the case is out of danger But when the disease is protracted sulphate of zinc or Moseleys tonic solution is to be given as a tonic. The latter article in a dose from a teaspoonful to a tablespoonful is an emetic in cases of great morbid action. Emetics of sulph. zinc & sulph. of copper have been recommended also of acetate of copper The latter article is also escharotic tonic & caustic. The chlorides chlorates are adapted to this stage of the disease [illegible] [chlorate of potassa] grii to vii “In those cases that require stimulants blisters may occasion gangrenes” “When there is tumefaction of the tonsils use blisters paediluvium & gargle with the mur. ac. especially the [oxymorestic] diluted with 6 parts water” 130 The treatment of the local affection of the throat is of two kinds, external & internal When there is much inflammation about the throat, with the uvula elongated, the tonsils enlarged an inflamed & the pulse full I apply epispastics externally. Blisters, mustard, oil of origanum ol. monard punct. etc. may be applied to the throat Gargles are injurious in bad cases & perhaps of little use in most. Still in ordinary forms of the disease from four to six ounces of any mild astringent acidulated perhaps with muriatic acid may be thrown in by a syringe. The marsh rosemary is considered better than any other astringent. The alum root (henchera amer.) is useful both as a gargle & given internally. For the latter purpose sweeten it & add a little brandy When there is not much tumefaction & considerable relaxation of the parts stimulating garbles are good, as capsicum & brandy astringents may be added. In gangrenous cases quinine is good if it can be got down. In the latter stages of the disease it may be useful to touch the ulcers in the throat with nit. silv. “Vinegar & lemon juice may be used as a gargle” “If the ulcers are thick and leathery apply nit. sil.” “I have seen the brain affected and much spasmodic action subderangement pain in the head and all the symptoms of hydrocephalus with a bloating of the whole cellular membrane pulse frequent & extremely quick and all the marks of irritative actions For 3 or 4 years I have used tinct. dose in 4-5 & sat. tinct. canth. in 10 3 or 4 times a day giving also the tonic solution and keeping the bowels open” “It produces eruptions on the skin, heat dryness & soreness of the fauces febrile action & if continued 8 or 10 days I think it would be useful. I would try it were the disease severe and epidemic, whether I thought it contagious or not” 131 The sequel of scarlet fever is dropsy. In children especially an anasarca and sometimes an universal dropsy comes on after the disease has subsided. The first two cases which I met with were in the severe epidemic of 1803. I treated them according to the direction of the books, with bark & brandy opium & lost my patients Considering this as an affection of the absorbent and nervous system I treated the subsequent cases which fell upon my hands with tinct. cantharides & tinct. digitalis The digitalis allayed the morbid action of the exhalents & absorbents & the cantharides acted as a diuretic. “Give of each 2 or 6 drops every 3 or 4 hours It [opens] [illegible] in these cases the effect of irritative action hence the propriety of digitalis Hanneman proposes to prevent the recurrence of scarlet fever by the administration of moderate quantities of atropia belladonna an article which produces an eruption upon the skin, similar to the rash of scarlet fever. The influence of belladonna, upon this hypothesis is similar to that of vaccination in preventing small pox. The termination of the chain of actions in health in some diseases & if we say nature cures the disease then we may say when the tendency is [inevitably] to death that nature commits suicide. The latter is true of this disease Yet if this chain of morbid actions is broken up by a powerful impression the constitution will take on its ordinary action Scarce any disease is more curable when taken in season yet it would not be proper for a physician to say he could cure all cases then pretending infallibility I shd doubt whether Good had ever seen the progress of a single case. He says nothing about the first stage. The tendency of the disease is to destroy the patient not by infl. or irritation but by suffocation from a foreign body in the trachea The stages run into one another, and yet a phys. watching the progress would naturally divide it into three stages Always curable in the first stage unless complicated with some other disease rarely in the second almost never in the last yet I have known cases cured in the last stage The peculiar sound of the cough is alarming (in the first stage) even to those who have never before heard it Dr [Hesark] I have been told divides the disease as I have done into 3 stages and directs to give 2 grs. tart. ant. combined with ipecac. I shd give for the effect not according to the quantity. I put out 3 or 4 gr and give till the effect is produced rarely over 10 grs 132 Croup This disease has been called in America by the popular name of hives which is probably a corruption of heaves called rattles The name given it by Good is empresmia bronchitis. The most common scientific appellation has been cynanche trachealis or angina trachealis The persons attacked by croup are I have never [illegible] 3 and [illegible] almost exclusively children from 3 months to 12 years old # in one instance I have known it attack a person 60 years of age When it occurs in adults it succeeds other diseases I have known 2 or 3 cups of [illegible] “Croup sometimes though less frequently than most diseases, blends with other diseases as catarrh” Some have considered the disease as contagious, but though a few facts appear to favour the supposition, they are not numerous enough to establish a general law. Croup usually occurs in the winter and spring, when it is brough on by exposure to a cold and damp atmosphere. Children upon the sea coast are more subject than in the interior of the country, because exposed to more variable weather and more frequent [thaws] & notwithstanding the greater warmth of the climate on the seacoast For when the air is filled with vapour, the caloric of the body is conducted off with more rapidity than in a dry atmosphere, even if the temperature of the latter is colder. # It is principally confined to persons under 5 years of age though it sometimes attacks persons of all ages, and It is not precisely entonic or atonic & hence might be called specific in peculiar It is said that in croup the exhalent arteries are affected & in catarrh this [illegible] vessels Whether the different vessels are affected or not there is certainly a different action “I have thought croup might destroy life by coating the entire surface of the lungs with a mucous or membranous coat thus preventing the decarbonization of the blood” “I have never seen croup without more or less spasm; & probably in fatal cases it is always a spasmodic contraction that closes the passage to the lungs which is only diminished by the membrane. I never saw a case on the other hand of what is called spasmodic croup which did not if neglected put on the membranous & inflammatory form” A similar [membranific] inflammation exists in the duodenum 133 Croup is a specific disease of a peculiar kind and is never malignant. It comes on with all the symptoms of pyrexia and consist in an inflammatory affection of the mucous membrane of the larynx and trachea, which causes a remarkable shrill sound in breathing & a ringing cough by which those who have seen the complaint cannot fail to recognise it. The proximate cause is a peculiar inflammatory action of the system, determined to the exhalent vessels arteries of the trachea and bronchial vessels, where there is produced an exudation of coagulable lymph similar to that which forms on the membranes of closed cavities from inflammation & entirely different from secretion of the mucous glands whether healthy or unhealthy. This coagulable lymph which is thus exuded, always forms a membrane which lines the larynx and trachea, if the disease proceeds to a fatal termination, and causes death by suffocation. This appearance is always found in the tracheae of those who have died of the disease. The membranific inflammation distinguishes croup in its nature, from catarrh which is in all its varieties, an affection of the mucous glands Most diseases attack in the night “Diseases are cowards, they mostly attack in the night” Rush. “The peculiar ringing sound of croup is made in [expiration] that of hooping cough is inspiration” # As is the case when respiration is impeded by any foreign body there is a great deal of irritation # when the nose discharges [illegible] [illegible] it bronchial vessels secrete mucus and a new action takes place the patient will be apt to recover # The patient was subject to asthma and the croup was neglected until the latter stages finally died + “I have known this to happen only once In this case the friends were not alarmed because the child had been subject to catarrhal affections & the symptoms received no attention till the last stage” # Frequently appears to be [illegible] in the very commencement of the disease 134 This disease sometimes come on like a catarrh and continues two or three days without any alarming symptoms, until suddenly, & often in the night the peculiar symptoms of croup appear. At other times the first symptom of the disease is a severe paroxysm of suffocation attended with the hoarse & shrill ringing noise made during expiration like air through a broken tube & the peculiar ringing cough. The cough in its progress is attended with more or less of spasmodic action. # It is always dry; and when it becomes loose or when mucus is expectorated the disease is broken up and there is no further danger # It rarely continues so long as five days and is sometimes fatal in twenty four hours. Sometimes, though rarely the membrane of coagulated lymph is coughed up. I have met with but one case + In this the membrane was thrown up three times, at each subsequent time forming lower down than before # No disease resembles croup so much as suffocating catarrh yet there are obvious marks of discrimination The latter disease as I have seen it is not attended with much cough and the difficulty of respiration is not in paroxysms but constant & commence with the disease. The pulse is often quickened and when the system is prostrated may be low. # In suffocating catarrh the powers of life are to be raised by external irritants & excitement equalized by the inhalation of the vapor of [illegible] of warm water etc. “Mustard” “If pulse tense bleed” From the earliest of my practice I have been in the habit of dividing it into 3 stages [illegible] that they are perfectly distinct, but [illegible] person would naturally take this view Quiet between the [per.] apparently not much affected during the paroxysms Between the paroxysms pulse natural & eyes bright. You will know this disease in this stage only during the par. Parents in this place know the disease in this stage and send forth phys. In this first stage, the disease must be broken up by a powerful impression upon the system This may be done many ways Some are partial to a [illegible] & some to another “That which is best administered is best” A local effect upon the stomach will not answer I have relied more upon tart. ant. than any other & found it answer all reasonable expectations. I have preferred it to any other I have occasionally used other [illegible] I have found seneka better as an auxiliary than as a commanding [remedy] 135 Croup may be divided into three stages each of them requiring different treatment. 1st The forming stage 2nd The inflammatory stage & 3d The last or suffocating stage 1st In the forming stage, the cough is severe & hoarse & occurs in paroxysms of from five minutes to have an hour in interval. “There is little or no fever” The pulse is regular and small, & sometimes trembling. The patient is often chilly. In this stage the disease may with certainty be cured “I have not lost a patient & have not saved one in [illegible] when not called till the second paroxysm had commenced” In the treatment of this stage we must depend upon emetics. Large doses must be given moderate ones do no good. A dose should be administered sufficiently powerful to affect the whole system and call into action every muscle. We must be regulated not by the quantity but the effect for we must calculate to overcome the diseased action completely by the operator of our remedy. I have given three grains of tartar emetic to a child three months old, & kept up the action by the large doses of seneka repeated every half hour for six or eight hours Tartrate of antimony is the best emetic to commence with and may be given in a dose of from 3 to six grains of strong tart em. After its operation a constant nausea must be kept up by seneka or some similar article, for some time in order to prevent a return of the disease. The seneka excites a new action in the system. It may be given in decoction. Take zfs or zi of bruised seneka to half a pint of water, & boil away a quarter. Give a table spoonful for a It has so happened that with us the [serpentaria] has not answered so well as tart ant. It acts on the fauces perhaps more [illegible] than tart. ant. but does not affect the system act upon the skin & determines to the surface so well as tart. ant. We have not used it however except in the latter stages & perhaps have not given it a thorough trial Sanguinaria vide p. 212 has been used 50 perhaps a hundred years. Three generations of physicians in one locality have used it and relied on it in croup with as much success as upon other articles These mode of using it was in strong decoction without weight & give a table spoonful until the desired effect is produced till vomiting is excited or the disease is broken up There are however forms of the disease where it fails even in [illegible] “Much has been said of the good effects of calomel Give in large doses 20 – 30 [illegible] acting as an emetic it is serviceable but when catharsis is produced, the emetics would fall in with the catharsis. I never could in such a case make the strong impression on the system what I [illegible]” 136 does once in half an hour or as much as the stomach will bear. Seneka has been relied upon by some as a specific in croup, but it is inefficacious when inflammation is present, being a stimulant, and it is too slow in its operation for the first remedy. After giving it as the first article, other emetics seem to lose their influence; acting as cathartics; but after the violence of the disease has been broken up by other emetics, you may avail yourself of the nauseating & deobstruent effects of the seneka & effect a cure. Dr Rush preferred the turpeth mineral 2 to 6 grs as the first emetic. The physicians in Wallingford for 5 years make a strong decoction of sanguinaria, and give it until emesis or a cure is effected. This article may be used instead of seneka in the way above directed In connexion with these means the warm bath and fomentations may be used as adjuvants. Much has been said of the good effects of calomel in this disease You cannot rely upon calomel for the cure of the disease It is too slow in its operation. Never give calomel until you have broken the violence of the disease After emetics have operated and you have availed your self of the operation of seneca & sanguinaria and the disease still exists, give from 5 to 10 grs of calomel By this producing an orgasm in the system more powerful than the disease & continuing it until the latter be overcome, croup may be cured with more certainty than most other diseases. All diseases should be attended I know that there are some very respectable physicians who rely upon calomel For this purpose they give very large doses and produce [illegible] & [illegible] I should prefer it as an auxiliar. I have often used it but after the emetic or with the emetic or before the emetic A variety of other men [illegible] India tobacco which though not allied in botany are so in their operations The common tobacco is generally applied eternally to the pit of the stomach. Lobelia acrid & emetic loses some of its virtues by drying In its recent state 1 gr will often excite full vom. Indeed I have known vom. prod. by merely chewing the capsules & [illegible] without swallowing by the impression upon the mouth Dose of tinct. 20 drops to a t. sp. according to age Other acrid narcotics as veratrum & colchicum may be used In this forming stage bleeding is not indicative by the pulse, nor by state of the system and you will obstruct your efforts to excite a powerful effort of the system if you bleed 2nd stage In this acrid emetics are injurious seneka is too stimulating Sanguinaria had I have seen all the symptoms aggravated by bloodroot in [illegible] the high entonic stage # “If the disease is complicated with a similar affection of the stomach & duodenum give calomel & other cathartics” 137 to in the beginning & it is owing to the imperfection of or our art that every disease is not broken up in its first stages. When however croup supervenes upon other diseases, it is more dangerous. “Those who practice in the country rarely see the disease in the forming stage. I had one winter 20 cases of croup all in town recovered most of the in the country died” 2nd Country practitioners however seldom see this first stage which I have just been treating of when the tongue is not discoloured, the fauces have a natural appearance the pulse is unaffected respiration natural & ordinarily no inflammation about the tonsils. On the contrary they too generally arrive when the disease is in the second or inflammatory stage the disease has effected in which the bloodvessels the skin is hot and dry, the face flushed, the pulse tense & sometimes full the tongue furred, respiration between the paroxysms difficult tongue furred, respiration between the paroxysms difficult and the cough so severe as to threaten immediate death vide p. 213. In this stage we should immediately bleed from freely from a large orifice the arm or jugular vein freely, even until syncope is produced put the patient in the warm bath & let him also inhale the steam of warm water, and give calomel and other cathartics. # Never give emetics in this stage until after depletion by V.S. when we may give 4 grs. of tart. ant. in a table spoonful of warm water & apply epispastics to the throat” in the commencement apply a blister” I dread to be called in this stage of the disease, for it is the almost always fatal venesection sometimes succeeds but very seldom. I would not apply leeches cupping would be better & perhaps friction might be serviceable. Digitalis has been recommended, but In this stage inhale the vapour cover the child & nurse in a chair with a blanket In this stage cal. & cath. may be given In the first stages I have conserved it very unfortunate to find my patient under the operation of a cathartic It feels as if my hands were tied The excitement is of a different kind from what is wanted And emetics are apt to produce hyper cathartics Where the dis tends to the [illegible] the [illegible] a specific. This is known by the cough being less hoarse, by fever, by constipation fever more intestinal membrane will pass off from the duodenum I was formerly disposed to cure this form of the disease [illegible] & described it as such In the second stage epispastics over the whole chest also diaphoretics and tepid bath When the cough is milder and beginning to be loos after being principally broken up in the first stage give cal. in 2 or 3 gr doses once in 2 or 3 hours In the 2nd stage remedies have been given to obviate the fever & digitalis has been used with good effect It was used as a depressing agent It operates by its narcotic power however. here refrigerants are of little efficacy In what may be seen to be the last 138 I have not used it. It is at best but a doubtful remedy in inflammatory effections though calculate to remove more irritations. Sanguinaria diminished arterial action like digitalis and operates powerfully as an emetic. I have not succeeded with it in the last stages of croup & have not used it in the first. [?ronchotomy] has been proposed, but does not promise much benefit, as the disease is seated below the place for operating. “Dr Smith did not recommend it” After depletion and especially after the disease assumes a bilious form you may give powerful cathartics The pt. begins to thrown his head back death may happen any moment 3d IN the last or suffocating stage* you may give emetics of turpeth mineral sulphate of zinc or even corrosive sublimate to throw off the membrane. Something may depend upon changing the emetics & sulphate of zinc may be tried. The cold bath is said to have been successful in this stage, but the fact is not well authenticated. I have used calomel and the warm bath with advantage. Child of Mr Culver [last] in chronic stage “I regret that I have not tried affusion of cold water in the last stage. It is said to cause the membrane to be thrown off & to procure relief even in the very article of death” vide p. 182 *”In the last stage respiration is constantly laborious head thrown back pulse often irregular & intermittent sometimes strong” Chronic form “Sometimes though rarely the disease is only partially subdued I [illegible] on in a chronic form. Calomel vapour best tepid bath are the appropriate remedies” 139 Angina Laryngea Empresma Laryngitis of Good, q.v. for a definition & an account of the disease In this disease the symptoms differ somewhat from those of croup, though the cough is similar The disease is seated in the larynx glottis and fauces & the characteristic symptoms is swelling of the tonsils. The cough is spasmodic and is excited by taking food with drink in this respect also indistinguished from croup. The disease is more violent and rapid than croup, as the inflammation being seated in the narrow part about the glottis produce suffocation sooner. The respiration is more difficult than it croup particularly between the paroxysms This disease more commonly affect adults The first case that I saw was that of an old man in whom the disease was brought on by exposure to cold after a pneumonia From a relation of his symptoms I prescribed seneca which only exasperated the disease, so that when I saw the patient he was unable to speak or swallow. A small red spot appeared on the tonsils. venesection, epispastics, pediluvium, inhalation of vapor etc. were resorted to with no abatement of the symptoms. Venesection was performed a second time & as soon as the patient was able to swallow, 4 grs. of tartar emetic were administered. Some nausea and vomiting with considerable catharsis followed. The vesication “Angina laryngea is mor apt than croup to recur several nights in succession” “The slough were thick and leathery. Sloughing even under blisters. In one instance blisters did not heal in 4 mo. Lunar caustic applied to the tonsils & uvula & inflamed parts proved serviceable # “In one case of A. laryngea I gave sanguinaria It was too acrid and increased the cough etc. It might do good if we could avoid the local effect of its acrimony” 140 was extensively returned & the patient recovered. Much the same treatment is required as in croup but it should be more prompt and with earlier venesection. For the inflammatory stage comes on earlier and the disease runs a more rapid course Last year this diseases differed in its appearance from the former years It has often followed certain affections of the tonsils called black canker. The tonsils are inflamed in black canker and sometime covered with a leathery crust. This comes off and leaves an ulcer. If the inflammation extends to the larynx, symptoms of croup supervene Case of black canker. Two called in the last stage gave blood root with disadvantage # Still at this late period calomel and other cathartics in large doses produced free evacuations and the child recovered Cathartics appear to do better than emetics. In one case after giving cathartics I used the vapour bath and applied a large epispastic over the whole sternum. Though at so late a period the disease abated. A large slough however was produced by the blister which required three months to heal. The morbid action on the skin being similar to that of the tonsils Vie p. 187 Sometimes comes on with a sudden paroxysm of suffocation sometimes gradually “Distinguished in its commencement from croup by the quantity of mucus in the bronchial vessels” “in the case which I have attended, not much febrile action attended the disease” Proximate cause a morbid action of the lining membrane of the lungs accompanied with a viscid secretion of [mucus] By vomiting the disease may be relieved & apparently cured but may appear again in the course of an hour The quantity of mucus is greater than in any other catarrhal affection” 141 Catarrhal epidemic resembling croup Peculiar catarrhal affection resembling croup suffocating catarrh This disease is characterised by a severe hoarse cough, much resembling that of croup. The disease is distinguished in its commencement from croup by the excessive quantity of mucus in the bronchial vessels which causes the suffocation The disease resembles croup likewise in the mode of its attack which is sometimes sudden with symptoms of suffocation, and at other times gradual with paroxysms of coughing and intervals of perfect ease The turns of coughing are so violent in this disease as to produce a livid colour of the face. The extremities evident determination to the head are cold and the head is hot from the quantity of blood thrown into the vessel of the head by coughing. The evacuation from the bowels are healthy and among children with no disease which I am acquainted affect the bowels so little ass this. The proximate cause of the disease is a morbid secretion of mucus on the lining membrane of the lungs & trachaea with obstructed perspiration. The quantity of mucus thrown out by this membrane in this disease is astonishing After the disease is fully formed, great quantities of viscid mucus may be brought away by vomiting, to the great relief of the patient for a short time, and yet within an hour the patient will appear to be suffocating from the the quantity again collected in the bronchial vessels In the commencement of this disease, the indication is to break it up at once by a powerful emetic, of tart. ant. unless the system The principal indication is to break up the disease by a powerful action on the skin on the stomach the duodenum and the fauces It is best affected by tart. ant. which is more difficult in its action than [ipecac] though is very delicate constitutions ipecac may be practicable # prevent accumulation of [mucus] The bowels shd be evacuated not for the purpose of curing the disease but for the prevention of an accumulation of feces which would be irritating In all diseases of the lungs examine the state of the skin and particularly that of the lower extremities for perspiration upon the upper extremities [only] may be a part of the disease I have known the lives of several patients saved by the use of the vapour bath I formerly [illegible] and used [illegible] for transmitting vapour by transmitting air through boiling water It was old practice to apply cat-skins fowls split open (to the feet) etc. with the intention of communicating vitality 142 is too much weakened to bear this treatment. This is a general principle viz, if possible to break a disease in its commencement by means of a strong orgasm. Often the emetic is to be repeated, and it may ever be necessary to give four or five emetics 1 gr [illegible] tart. emet. each in the course of a day. After the disease is somewhat broken up, and epispastic applied upon the breast will assist much in allaying its violence # If the disease still continues or if when first called we find it fully formed and powerful emetics inadmissible the primary indication will be to open the pores of the skin and keep up a gentle perspiration, by small doses of antimonial wine to which may be added in all quantities of camphor by elix. [illegible] & in some cases tinct opii by fomentations and especially by the warm bath and the inhalation of vapour. To affect the latter object the child may be placed in the warm bath & a blanket thrown both over it and the nurse, so as to keep the child in an atmosphere of vapour. Long continued perspiration invariably relieves the symptoms. I have known an instance in which the skin of a sheep warm from the animals body was wrapped round the naked body of the child with beneficial effect. In small children when the stomach ceases to be excited by emetics the throat should be irritated by a feather or the finger, when we wish to produce vomiting For we must never rest satisfied with merely endeavoring to palliate the symptoms. In small children also the mucus should be wiped out of the mouth by the finger or a cloth This disease prevails most in the winter and spring months & does not occur every year. The first patient that I treated for the disease suffered from it a year. I gave mercurials & finally the silver pill (nit sil) 143 I was puzzled with the first cases of this disease which I met with. Some of them continued for weeks and months I was obliged to use perspiration, by warm bath to vapour bath emetics etc. I determined to break up the next cases in the commencement with tartar emetic repeated until full vomiting was produced walking my patients. This plan was more successful A s a general rule break up all diseases if you can “The complaint is epidemic or rather endemic. It has been mistaken for croup, but it differs As croup formerly occurred no mucus was raised in the earlier stages, and when there was an excretion of mucus we considered the disease cured But of late years the two complaints are somewhat blended. Mucus is thrown off sometimes without permanent relief” “There is often in this disease a disturbance of the brain and nervous system resembling epilepsy or chorea produced by the cough” A distinction was formerly made by some writers and some practitioners, between hooping cough and [chin] cough the latter being a spasmodic cough without the hoop. Such a distinction will not hold good there is no difference “Linneas and Rosenstein attributed it to an insect others to malaria” There had been a very severe winter & no one had left the island for months 144 Hooping Cough Pertussis Called also chincough This is a disease which generally attacks children yet occasionally, adults are the subjects. I have known persons of 60 years of age affected with it. As a general rule also it does not affect persons a second time. I have known about 20 or 30 exceptions & among them was the late president Dwight at 60 years Hooping cough generally appears as an epidemic. With respect to its origin there is considerable difficulty in making up an opinion. It is said to be contagious to arise from a specific contagion which affects a person but once. Dr [Dewers], however, says “We confess that we are inclined to believe that it depends upon causes of a more general and pervading influence that contagion.” Dr Cullen asserts that he has said a disease which though evidently arising from chincough contagion never put on any other form than that of common catarrh. In the tenth volume of the medical commentaries DR Willey gives an account of the breaking out of the disease on Block Island under such circumstances that it would seem that it could not have originated from contagion. When the disease prevails many become effected where every precaution is taken” When the disease has been extensively prevalent I have not been particular about keeping patients apart, perhaps however it is best for prudence’ sake to consider the disease as contagious and to treat it as such. One fact I have noticed that in particular seasons may have the disease who have had it before.” Some suppose that it is contagious only in the first stage others in the second “Some think it caused by malaria or animalcular” “The stricture may be overcome by not attempting to inspire, but to expire till the lungs are emptied the pat. can then inspire without difficulty I have known persons subject to this kind of hooping without cough Adults are sometimes attacked in the night with paroxysms of suffocation they start from bed when the recover their breath there is hooping but no cough, at least at first The more they struggle to catch breath the greater the difficulty there seems to be a spasm of the glottis Let them make no effort to inspire but expire the little air remaining in the lungs & they will bye relieved at once. The disease is liable to recur bathe the feet at night give paregoric wine whey diluents The disease is not described 145 Some suppose this disease a peculiar inflammation of the mucous membrane of the trachea and lungs, others that it arises in the bowels This disease often commences with the symptoms of ordinary catarrh & continues without alteration for some days. Sometimes the peculiar mark which gives this cough the appellation of hooping & distinguishes this disease from every other does not appear until the 3d or 4th week It is impossible however to distinguish the disease until this peculiar hooping makes its appearance. When the disease is prevalent it will be safe to treat every severe case of catarrh among children as one of this disease The phenomena peculiar to this disease may be the described. Several frequent expirations are made in succession by spasmodic coughing, and a full inspiration is then necessary to restore air to the lungs. The air as it passes rapidly into the lungs produces a loud sound called whooping The sound however is made more by the structure of the passage than by the rapidity with which the air is drawn into the lungs I have known persons subject to this kind of whooping, without having a cough caused by a spasm of the muscles of the trachea larynx? to which adults are sometimes subject. (Goods laryngismus?) A similar sound is also made in croup, when the air is expired after the passage becomes constricted The patient is aware of the coming on of a paroxysm of coughing by an unpleasant sensation in the throat, & The cough is violent in proportion to the shortness of the paroxysm 146 it is common for children support themselves during its continuance by changing to a chair or other support near them. During the paroxysm the blood is returned with such violence to the head as to produce a livid colour of the face & often in bleeding at the nose. Very violent paroxysm sometimes in young children terminate in convulsions or death The paroxysms continue until a quantity of mucus is thrown up from the lungs or the contents of the stomach are evacuated by vomiting They are short in proportion to the facility with which the mucus is brought up or rather in proportion to the rapidity with which it is secreted It is the secretion of mucus, not its removal which gives relief to the irritation of the lungs Many suppose that this mucus which is generally in considerable quantity is the cause of the paroxysm of coughing instead of the effect of it. The peculiar irritation of membrane in a paroxysm of coughing produces a secretion of [illegible], and when a sufficient quantity has been secreted it is coughed up like the secretion of tears from an irritated eye and the paroxysm is relieved “The mucus sheaths the part & the ceases” The disease continues from one to six months It is often kept up by habit. The cough is usually more violent by night than by day. Violent cases are often attended with considerable fever and in the worst cases respiration is laborious between the fits of coughing. The disease may terminate by apoplexy or suffocation or by ulceration of the lungs and hectic & sometimes by permanent visceral obstruction “or apoplexy or suffocation” Whooping cough is not dangerous to adults and I have never known a child over two years of age die with it. It is most dangerous to infants and the younger the It is usually dangerous to children within the mouth It is apt to wear out very young children especially if they are of a scrofulous tendency It is frequently accompanied with a morbid sensibility and irritability of mind and hence in the latter stages a change of air and of place is salutary as in cholera infantum The same despondency of mind takes place as in chol. inf. q.v. The disease is a fever spending itself upon the lungs and trachea, and affecting also the glandular system Some phys. think this dis. like common catarrh, is always inflammatory in its commencement, and requires antiphlogistic treatment. But we know that pneumonia may be highly typhoid & require treatment opposite to [enteric] pneumonia. If infl. of the lungs exists the antiphlogistic treatment shd be adopted in its fullest extent I have seen antimony as efficacious in this dis as in pneumonia. In general perhaps mild antiphlogistic diet & treatment will be proper. In some cases I have thought the veins lost their power, and in such cases the blood [illegible] has been prescribed & with advantage It is a catarrhal fever at first and to be treated as such 147 child the greater danger in children under the age two years The anger, to be apprehended from the disease will also depend upon the debility of the child when attacked. The cough may be violent and attended with frequent vomiting yet of the patient’s appetite be good there will not be much danger to be apprehended. A moderate hemorrhage from the nose is often salutary Treatment. If the disease is mild and the constitution good little need be done with the way of treatment. But if inflammatory symptoms supervene with a tendency to pneumonia the antiphlogistic treatment must be adopted. Bleeding will often be advisable. A small quantity of blood taken from the arm proves serviceable. In general greater effects may be expected from the application of a few leeches to the breast or neck than from bleeding at the arm but when decided symptoms of pneumonia appear, & the blood seems to be transmitted with difficulty through the lungs. I would recommend venesection. In this case also the bloodroot will be the best article for internal administration In most cases the disease comes on like a catarrh, and should be treated as such, with mild antiphlogistic regiment [illegible] important part of the antiphlogistic treatment of this disease is the keeping the bowels open. Costiveness frequently attends the disease & should be carefully avoided. In general it is better to obviate this symptom by diet as far as it can be done Begin with antimony in small doses 1l or 2 drops ant wine & in [illegible] For very delicate children however it may be better to give ipecac Almost all the writers recommend vomiting [Best] 148 rather than by medicine. The best cathartics for the indication are those which excite the secretions of the stomach and liver. Sometimes the disease has a tendency to produce congestion of the liver and obstruction of the mesenteric glands and in that case also mild mercurials should be given and their use continued as long as any symptoms of congestion exist. All the medical writers on this disease recommended vomiting in the first stage Tart. ant. is in ordinary cases the best emetic. Sometimes for a child from two to six months old two drops of antimonial wine will be an emetic dose while for another of the same age 20 or 3o drops may be required. In affections of the lungs children will bear antimony better than in those of the stomach and duodenum. In some constitutions antimonial emetics produce (in this disease) a sort of spasmodic stricture other emetics also may produce this effect a symptom which must be relieved by diluents and opium In general antimony in small doses may be given to children of any age, either by itself or combined with a small quantity of paregoric or any other mild preparations of opium. Given in this way it removes febrile action and congestion of the lungs, and determines to the surface When the disease has proceeded with You may see the fontanelles swell in such cases. I recollect a child in the whooping cough going into the country I told the parents not to suffer the child to be vomited. A physician in the country said the child must be vomited of course all the books directed it in whooping cough He vomited the child. It went into convulsions and died # Here insert the recipe for hire syrup or compd sys. of squills p. 150 I have known the lives of some patients saved by this antimony internally had lost its power produced no effect 149 violence for some time and there is much determination of blood to the head, threatening convulsions or apoplexy from distention of the blood vessels, or when the patient has become debilitated vomiting by emetics should not be practises or but cautiously. When the system and particularly the stomach has become debilitated. Ipecac is preferable to antimony, given in emetic doses, or in small quantities as an alterative diaphoretic and antispasmodic. And in the latter stages likewise on account of the debility, sulph. tinc. is a good emetic using 5 or 6 grs. with as much of ipecac If there is not much febrile heat, and there is much viscid mucus in the stomach and lungs, and emetic of squills is often serviceable # particularly I [illegible] phlegmatic temperaments syrup of squills vinegar of [illegible] In this disease if there is danger of convulsions from vomiting, blood root and similar articles should be given. The hive syrup or compd tinct. of squills may be used In children under three 6 months, whooping cough may be much relieved (respiration being promoted) by vesication on the breast. A blistering plaster may be applied but I have more generally used the following. Rx common or mild tinct. canth zi targ. ant zi Dissolve the ant. in the tinct. & apply a linen cloth with the mixture till [illegible] or partial vesication is produce & then dress with simple cerate In this way we have the vesicating & irritating qualities combined. This external use of tart. em. was recommended 20 years ago, in the Lon. med. & ph. Journ. This disease may be cured in its first stage but it ordinarily runs a regular course & the treatment is generally palliative brown mixture You will perceive that this is a strong decoction of seneka and squills, with a large proportion of tart ant. shd be given cautiously 4 to 30 drops Narcotics have been strongly recommended e.g. atropa belladonna & hydrogen of the former for 2 gr of the leaves in powder Alibert recommends the fresh bruised root 150 A popular remedy in whooping cough in Godfrey’s cordial, made of molasses and water with a little laudanum and oil of [illegible] “Hive syrup” (or compd syr [illegible]) is made as follows Rx bruised seneka root & squills zz z8 water lb 8 boil and evaporate one half strain and add honey 4 pts boil to lb 6 Add tart. ant. gr.i to every ounce Give for an emetic 8 or 10 20 drops to a child 4 mo. old & repeat the dose every 15 or 20 minutes until vomiting is produced The “brown mixture” is as follows elix. pareg. zi; ant. wine zfs; ext. glyc ziii pul. gum ar. zii wat. zvi trit. & boil dose from ½ teaspoonful to tablespoonful This has been very extensively used This disease has been prescribed for more empirically than most others; a fact which proves the difficulty of curing it It is a popular notion that it must “run its course” & under the influence of this many parents object to its being prescribed for. Undoubtedly this like every other disease must “run its course,” if it is not cured; but this is no reason why the cure should not be attempted. Ammoniae asafoetida (especially if the cough is kept up from habit) 1st antispasmodics 2nd tonics # An emetic is occasionally administered with advantage “I have prepared this from seneca oil also from gun copal” 151 2nd In the second or chronic stage tonics & antispasmodics are indicated. Sulph. of copper or of zinc tinct canth. cinchona, arsenical solution etc. may be required to rouse and support the system & as antispasmodic tinct. asafoet. petroleum Artificial musk etc. and also the narcotics, as hyoscyamus, conium, stramonium, belladona arnica, opium etc. When the cough is kept up by habit, # asafoet. is often administered to children with advantage. It may be given in tinct. or decoct. & if it cannot be given by the mouth it may be thrown up in an enema, using 10, 20, or 30 drops of the tinct. It is a valuable [illegible] the taste is less unpleasant than the [illegible] Artificial musk or oxygenated oil of amber was first introduced by Prof Hufeland of Jena as a specific for whooping cough and has since been found very useful in other spasmodic diseases vid. Lon. M of ph. J. vol. 1: p.181 van Swieten’s comm. etc. Rx nit. ac ziiifs cl. succini zi. And the acid gradually, ina temperature of 100 [degrees] or in the sun. Prof. Hufeland triturated x or xii grs. in a mortar with a few almonds & diluted with z 5 or 6 of water & gave a teaspoonful every 2 hours to a child a year old. This preparation was very celebrated and very effectual, for a time, but afterwards fail was thought to be ill prepared. The truth was the diathesis had changed. Probably it will be as affectual at [illegible] time I have given the above article in tinct. Rx zii of the oxyg. [illegible] [illegible] lbfs alcohol dose 10 to 12 20 gtts It is much more soluble in ether. I frequently dissolve zi of oxygenated amb. in zi of ether dose 1 to 2 drops on sugar 152 It may be prepared indeed of any strength, to suit the convenience of the physician. Probably gum copal oxygenated would answer the same purpose as amber as there is every reason to suppose that the two are essentially the same amber being gum copal mineralised Case of a vein of olibanum or Frankincense found in S. America. Opium is not indicated in this disease except when it is qualified and its action determined to the skin by antimony ipecac or camphor. Hyoscyamus is better than opium for in the cough it produces no constipation and the tincture is very pleasant. I have not however used it in this disease. Conium has been recommended by writers of the first respectability, but later authors do not speak of it with much confidence. It deserves a trial when other things fail. Alibert recommends atropa belladonna 1/6 gr. of the root or leaves powdered & given in milk I have used I have more confidence however stramonium in the [illegible] & think it preferable most of the narcotics to any other narcotic It is peculiarly calculated to remove spasmodic action depending upon irritability of the system or kept up by habit From the relief obtained by its use in asthma I was led to employ it in this disease and from those cases in which I have tried it I am of opinion that it is a very valuable remedy in it The ripe seeds of the stramonium are best the full dose of these for adults is gr. ii for a child 1/10 gr. or more according to the age Mercurials occasionally blue pill rhub & ipecac enough to keep up a gentle excitement in the bowels Not unpleasant to the taste An old [illegible] Chalmers ([illegible] of silver) recommends sulph. cop. & tinct canth in wh. cough # [ago] more used than any other Lately the ox. bis. has taken its place dose the same used for irritating cough & irrit. of stomach 153 Carb. potash is a good antispasmodic used externally and internally. It is not only antacid & antispasmodic but it appears to me to produce a peculiar excitement upon the stomach and aesophagus, which makes the more susceptible to the impression of other articles. Pearlash zfs & water z8 with cochineal enough to colour the solution has been considered relied on by some physicians a specific. The cochineal merely colours the solution. is an article from which I never could perceive any medicinal effects when used alone. I have tried the experiment & could perceive no medicinal effect from it Tonics. I have given the sulphate of zinc more than any other tonic in this disease, and have experienced the greatest benefit. Sulph. tinc given by itself, sometimes produces spasmodic action, the effect I attribute to its being used in substance & hence I always give it in the form of Moseley’s tonic solution. This preparation is both conic and antispasmodic is easily taken and retained on the stomach of very small children Sulph. copper possesses properties similar to those of sulphate of zinc. It is administered in the low stage of whooping cough. In this place the preparation of it called compd tinct vitr has been used according to the recipe in the 10th vol. Duncan’s Commentaries in doses of 3 to 30 drops according to the age of the patient The oxide (or flowers) of zinc & also bismuth formerly much used in spasmodic cough 30 grs have been occasionally used 1 to 3 grs 1 to 10 to an adult The Peruvian bark is a good remedy in the last stages. The only objection to it lies on the difficulty It sometimes happens that the physician is not called in until the latter stages. As one resort we may have recourse to irritate along the spine It is an opinion very extensively prevalent to that it is of no consequence what kind of food a child takes when he has the whooping cough But great attention shd be given Removal from sea side to country and [illegible] country to sea side either is beneficial 154 of administering to small children, a quantity sufficient to produce any considerable effect. This difficulty may now more be overcome by using sulph. quinine ¼ gr to 1 gr Dr Chalmers of South Carolina recommends a combustion of bark, sulphate of copper and cantharides Tinct. cantharides has been long since recommended for whooping cough. It is useful when the system requires an inflammatory diathesis to be produced. Its action on the stomach is probably similar to that which it has in cases of gleet and leucorrhoea the stomach being in a relaxed state & requiring to be excited to a healthy inflammatory action Irritants, as oil of capsicum canth. [illegible] or ol. orig. or vol. lin. rubbed along the spine have been used in the latter stages. They should be tried when you have reason to suspect that the spinal marrow or the nerves proceeding from it are affected. Attention should be paid to the diet of children in the whooping cough avoiding potatoes, oily foods etc. Change of scene & change of air especially by riding should be resorted to in bad cases, to tranquillise the patient & furnish mental excitement. Sometimes the little sufferers will be excessively irritable constantly worrying and teasing until this is done requesting first one thing & the other to be done. It is the worst of such cases, medicine does little good, even the irritation produced by administering it may counteract its beneficial effects. violent palpitation throbbing of the heart a soft flowing pulse and a jarring feel of the pulse under the finger ([illegible]) (The French call an enlarged heart hypertrophy I object to the [name]) For this I have given nit. sil. 1 or 2? gr. (in the chronic stage of [illegible]) Digitalis & also [languinaria] (tinct. 2 or 3 gtts.) This article is dangerous for children because it accumulates in the system Lead has been recommended I have been doubtful with respect to its propriety in affection of the lungs etc. # Pneumonia typhoides 1815 the system seeming to lose the power of [illegible] the blood and the bloodroot was given to promote venous absorption The digitalis might probably be given in such cases but is not as well adapted. I used the blood root and found as much benefit as could or [expected] from any article 155 If the patient having the whooping cough happen to be teething the treatment recommended for dentition should be employed The patients are very liable to have an inflammation of the lungs from taking cold in any stage of the disease & in such cases the remedies for pneumonia should be administered, such as antimony bleeding epispastics, bath etc. The disease I think sometimes determines to the head & produce a relaxation of the sinuses & [illegible] likewise produces a relaxation of the ventricles of the heart the immediate cause being the violence of the cough In such cases I have used lead, but not in sufficient quantities to enable me to recommend it Iodine has been recommended 2 or 3 doses 3 times a day Nit. sil. languinaria & digitalis When in the progress of the disease the circulation becomes much affected the pulse frequent, soft, flowing with occasional intermission respiration high frequent and laborious, with a bloated and sometimes analogous to # a livid countenance, the blood root has done more than any other remedy not failing in any instance to give relief & palliate sympt & in some cases the relief has been permanent. I gave the bloodroot repeatedly, the last spring, 1815 to my patients in the whooping cough. To a child a year old 5 to 10 or 20 grs of the dried root, according to the urgency of the case, infused in 6 or 8 teaspoonful of boiling water. Give a teaspoonful every hour, until vomiting is produced or the patient relieved. Children Sometimes the dis. will be very mild and yet leave the system in such a state that a slight subsequent disease will carry off the patient e.g. in 1815 the dysentery attacking children would often be very slight and yet would carry off every one who had had the whoop. c. in the spring. The attack would be mild and insignificant of dysentery and yet the pat. would go into a [illegible] very speedily like cholera Elaterium has been recommended I shd be cautious in trying it except in very vigorous children I can speak with confidence of arsenic. Excepting occasionally prussic ac. I know of no remedy which so completely cures the wh. cough except prussic acid in some cases. Case child 2 gtts night & a [illegible] in a weak countenance pale, eyes dull face bloated muscular strength weak muscles soft & flabby Parents much [illegible] cough gone recovered colour & strength upon bark I have known several such cases and have known no ultimate injury result from this practice Yet parents are afraid 156 who had the whooping cough that spring were very liable to be carried off by the dysentery of the following summer none died in 1815 of the disease but many in consequence of it, with hydrocephalus and dysentery Prussic acid dose 1/3 of a drop to begin with and arsenic occasionally cut this disease entirely short; and these are the only articles which I have known do so, without leaving a vestige of the disease behind. The former is a dangerous article to use, from its want of uniformity and strength Fowler’s solution of arsenic gtt more [illegible] is safe but does not answer so well in the first stages. If it makes the patient feeble livid bloated & with swollen lips etc. it must be stopped & perhaps bark administered. It has cured the cough in the second stage. Dose 1 drop 1 or 2 drops twice a day. Sometimes is only palliates Case. June 1815. A child of Capt. Totten’s a boy of 5 yrs of age rather full habit had been affected with the cough for a fortnight before I saw him I found his pulse very frequent soft convulsive & with intermissions face swollen and livid, circulation much increased on slight palpitative [illegible] motion of the body in the symptoms aggravated to an alarming degree by a paroxysm of coughing. Previous t the disease a remarkably even tempered and pleasant child he was not on the contrary very irritable. Trifles irritated his mind, and when irritated, all the symptoms of his disease were aggravated. He took an emetic of ipecac, with The sequels of this disease are numerous Sometimes the heart is affected as above and continues so for years. Sometimes the glandular system is affection. Sometimes the lungs. There is a lady in Philadelphia who had (under my care) suppuration of the lungs whoop. cough now healthy hence never despair The stomach and abd. visc. are sometimes affected in a chronic way requiring dandelion mercurials hop [illegible] etc. It is very tedious to attend children in the chronic stage an account of the excessive irritability When bath recommended Cold bath doubtful. I have known patients killed by being brought from the country and plunged in the sea bath “Good speaks highly of rhus [illegible]. It is given to produce a distinct action on the system which shall overcome the diseased action. It determines powerfully to the surface and has a powerful exciting effect on the blood vessels while it does not produce a determination to the brain. I should not recommend this article and it is so uncertain in its effect. On one person it will have no effect at all, when in another it will cause swelling of the eyes, blindness, fever, & great irritation 157 but inconsiderable & temporary relief. He was directed to take the bloodroot every hour, as much as the stomach In relieved the violent symptoms would bear. It was continued for two or three days, and the palpitation of the heart was much abated, the circulation was less irritated, & the livid colour of the face was gone still did not cure When costive he was benefitted by full doses of cathartics. because the system was [illegible] deranged heart lungs etc. I considered the case a fatal one and expressed that opinion to the parents. The cough and other symptoms continued though in a less violent degree disease chronic an epispastic was applied to the chest very irritating (changed clothes often in the day [child] run upon various subjects) Patients strength began to fail and tonics were given white vitriol bark cantharides Finally the patient refused to take any medicine and was left to his own appetite called obstinately for it took cake for food for several days then baked pears then [illegible] Afterwards recovered but was unable to run “for some years” without a palpitation If this disease should again prevail I think I should atropa belladonna as a prophylactic. As the disease continues the stomach may become very much debilitation and require compd powd of [contragerva] cat carilla etc. etc. “Ledus palustra are narcotic” It is not certain that the dis. did not exist before It may have existed before but no general account given of it. It may have been known in diff. places by diff. varies and it [illegible] have been known than the diff names meant the same disease Diseases are not apt to appear suddenly. Still at this period, there [illegible] cause operating for the increase of the dis. Belly usually large and limbs small Joints unusually large Often morbid cravings of appetite Yet the same causes operating in a higher degree produce cretinism There is no difficulty in recognizing the disease You will be struck at first sight with the large size of the head the blue [veins] of the forehead paleness of countenance as you cast your eyes down you will notice the large joints 158 Ricketts This disease according to Underwood was first noticed in England in the year 1628. It is said to have immediately succeeded the increase of manufactures, when people left the villages to settle in large towns, where they wanted exercise and a pure atmosphere Children are rarely attacked with this disease earlier than the sixth month and not usually until after that period. The symptoms are soft flesh muscles & cell. sub. relaxed general relaxation of the system paleness of the countenance unless the face is flushed with fever, which when it exists is of the hectic kind a fever of irritation pulse, usually quick and feeble, tumefaction of the abdomen appetite and digestion bad tendency to acidity veins of the head [illegible] and blue the sutures of the head not firmly closed head large fontanells unusually open joints large in bad cases all the bones of the system enlarged & softened One effect of the disease is that the teeth are cut later than usual. Ricketty children are usually precocious in intellect. Their mental faculties are developped more early but are not capable however of so much improvement, as those of others. Evolution of the mental faculties does not proceed with the tardy progress of the assimilating function The child learns to [illegible] very early and exhibits an acuteness of intellect beyond his years with the exception however of those cases so severe as to have a tendency to cretinism It is a common saying that very forward children are not likely to live long and the precocity of scrofulous & rickety children may have contributed much to the production of this impression. Too much heat may produce an indirect debility Undoubtedly aff. the brain & nervous system Give mercurials occasionally Do not produce salivation and do debilitate by mercury Frictions are very efficacious exciting the skin The reasons why friction are not more successful is that they are not perservered [illegible] the al. can. etc. The cold bath is the only strengthening remedy which acts suddenly No effect can be produced by any medicine equal to the astonishing effect of exercise & amusement in many cases of chronic aff. of stomach & bowel. 159 The causes of this disease as in some instances a predisposition transmitted from debilitated parents sometimes a syphilitic taint of the parents In others bad nursing the children being kept wet and dirty and confined in close & damp apartments or if the child has been carefully fed and kept clean debility produced by confined air too great warmth, too great variety of food and as some think too much saccharine matter in its diet. Inanition may be a cause. The disease prevails among the Alps and is perhaps there caused by the combined influence of cold and moisture This is a disease of debility nearly allied to scrofula & cretinism affecting the viscera of the abdomen generally, the lymphatics and the [isseous] system. The chylopoietic viscera are probably first and afterwards the mesenteric & lymphatic glands generally the indications are to give tone to the system and excite healthy secretions The diet should be dry and nutritious and such as is not only easy of digestion but rather stimulating and the bowels kept open by cathartics which act on the secretions. A dose of calomel with a little ipecac will be useful. The cold bath should be used every day Take the child out of bed in themorning bathe & return. If the Cold bath of salt water is [illegible] tonic patient be very feeble it should be begun with at of a temperature of about 80 [degrees] and gradually used colder The child bath is equal to all other remedies It is more tonic if made of salt water As a substitute for exercise, frictions will be very useful But exercise in the open air should be like whenever the weather is good in a carriage or on horseback and exercise should be so managed as to afford amusement and mental The [guephalin] [polyapt] & also the gr. marg. (which is less odorous) are also used Their agreeable odor if there is no other advantage will prove grateful stimulus & promote healthy secretions Take the child out of bed and plunge him in water (about 70 at first) and replace him in bed Yet in exhaustion of fever the cold bath gives a shock from which the system will not react but yet in the debility the cold bath is highly beneficial whether we can explain it or not. It may be necessary to vary the tonic And it is desirable to have a variety of tonics to [chorea] from also carb iron & tinct. carb. iron ac. fer. alkaline solut The sulph. zinc is not inferior to iron and is not subject to the inconveniences of iron not producing inconveniences Mosely’s sol. The compd tinct vitr. although apparently [illegible] is yet certain in operation and has been long used in this vicinity A tinct. of potash is thought very useful to rub the body with. It is a popular remedy & has sustained its reputation in this neighborhood for many years Lime water made of caustic lime is more tonic than the carbonate That made of shells is thought better being pleasanter than that made for stores probably not as pure but containing muriate of lime. Be careful to see that the shells are thoroughly burnt so as to fall in powder when 160 stimulus by the sight of scenery vegetations, flowers etrc. The patient may even be benefitted by being carried in the arms into the garden and amused in this manner. It must not be forgotten that this cheerful excitement has a powerful effect on the secretions. Feather beds should be prohibited. They are too enervating, and hard ones should be used in their stead. Beds made of the sweet fern (comptonia [asph??folia]) are popular & do very well. They not only from their hardness check the profuse perspiration of the hectic diathesis, but correct the acid smell of the sweat which is very common. IN general heat should be avoided as too relaxing I have rarely failed of curing the disease by the cold bath as the principal remedy, using tonics however as occasion may require. The tonics which we may use are sulphates Phosp. & mur [illegible] 3-10 grs of zinc & of iron muriate of iron martial flowers of iron etc. and the plan has been tried of applying finely powdered bark eternally in a quilted jacket of flannel. It is difficult to give bark in substance to small children. Astringents may be indicated & there is often a degree of acidity so great as to indicate a free use of absorbents The alkalies as pearlash may be beneficial internally & frictions with pearlash & water zfs to a pint may be recommended. Of late iodine has been given in doses of from 2 to 4 drops of the alcoholic tincture 3 or 4 times a day, given mucilage or other convenient vehicle. This article when persevered in has cured a great many cases. It should be [given] at first in small doses & the quantity be gradually increased or a disgust towards it may be created Phosphate of [illegible] was popular Forgetting that the deficiency of [osseous] matter may be defect in the action of the secretions Though the theory was wrong yet the practice was found beneficial absorbents Give a solution of the acid of about the strength of lemonade The phosporus is preferred to the phosphoric quenches in the water you will then have, not as is too commonly the case merely smoky water but lime water of full strength These preparations are called tonics by Good called stimulants (too loose as use of the word) Long before I had any explanation in [illegible] I thought I observed that these articles created a susceptibility to the operation of tonics apparently as generating excitability 161 It has been supposed that the proximate cause of this disease is a deficiency of phosphate of lime with bones but this is an effect, caused by want of action as those vessels which secrete this substance. The proximate cause, as it is called, is in this case the disease itself. In consequence of this notion burnt bones have been much prescribed. They are probably useful not as supplying the matter of bone but as an absorbent & perhaps as a tonic Acids especially the phosphoric have been given. Phosphate of lime has been used with benefit muriate of [illegible] and barytes were formerly much prescribed. The worst cases are those of children born of syphilitic parents for these tonics mercurials and the cold bath will also be the treatment. I give them corr. subl. 1/30 gr with no injurious effect Nearly allied to ricketts and often as sequel of it ricketts often running into it Sometimes appears with ricketts sometimes afterward Ricketts occur with the year. Scrofula occurs later. Ricketts children are more generally of a scrofulous temperament The tendency may exist in the parents and yet be developed only in the children from the causes of bad food [illegible] pain etc. These swellings may continue in children of 5 or 6 [illegible] or within the year with little or no change but increasing of size in spite of poultices filling the whole neck I have found poultices apparently injurious promoting the relaxation but blisters would stimulate and bring on a suppuration. The pus will not be healthy but curdy and whey like The edges will be ragged, not unite readily, and will leave a bad scar. Scrofula, ulcers are said to be distinguished by a smooth overlapping margin. the disease may continue for months and years with little or no change of it does not attack a part essential to life as the lungs, producing tubercular consumption attacking the liver producing a peculiar atonic infl. I have seen cases of scrofula that were [entonic] They were injured by tonics and benefitted by cal. and ant. They would have borne bleeding 162 Scrofula This is a disease of the lymphatics and affects persons of a peculiar temperament this temperament is characterized by a fair, thin, translucent skin, light hair, blue eyes, sometimes black hair and eyes delicate fullness of lips & nostrils usually texture of skin and cellular substance general laxity of muscular fibre usually delicate organization mental faculties developed early on in ricketts. Person who have been affected with ricketts in infancy are after affected with scrofula in after life. This peculiarity of constitution, when a morbid action is superadded, gives rise to the following symptoms First small swellings appear about the neck, slow in their progress & with an imperfect suppuration. Small holes form in the swelling and discharge a subpurulent, watery and flocculent fluid. These scrofulus ulcers when fully formed are distinguished by smooth spongy and overlapping margins & by very lax granulations. The disease forms tubercles upon the lungs, liver kidnies & ovaria & causes a great enlargement of the mesenteric glands This morbid condition and action may be transmitted from parents to children. It prevails especially in cold and variable climates exists most in large manufacturing towns where it is caused by bad food and air, want of cleanliness all of them debilitating causes It is sometimes also in persons predisposed, a sequel of other diseases particularly of small pox, hooping cough & measles Treatment. more may be accomplished in the treatment of scrofula by diet, exercise, sea air etc. than by remedies. Scrofulous swellings should be treated by Avoid cold vegetables & watery diet give animal food articles containing nitrogen as infants are said to abound more in albumen and adults to be [illegible] “Iron zinc copper silver tonics & antispas. are useful” “Conium 2, 3, 4 grs with carb. fer. 10-20 grs” # “I have used with advantage mur. lime 3-4 drops increased to a tablespoonful & also mur. [illegible] 3-30 drops given in milk & water or in coffee. They are tonic & act on the lymph. & gland. syst.” Articles containing [illegible] In [anthelmint???] vesicular [illegible] F. idealis ([illegible]) (sea cabbage) has been given for worms and some families learn their children to cut it A mucilage may be made F [vesiculosis] [illegible] which with bran has constituted a popular poultice for scrofulous tumours When there is loss of tone & an ill conditioned discharge cantharides with opium is a valuable excitant Never continue any remedy after it debilitates by exciting disgust and nausea Mercurial plaister of the shops (gum ammoniac & blue ointment equal parts) has been much used especially for scrof. [swell.] of the joints In these [illegible] become extensively effective and become spongy A man at the westward was very celebrated for curing scrofula. He used wild violets but was not particular as to which species he used 163 blistering van Heuvel’s child a round of remedies had been tried [illegible] Occasional purging with calomel and rhubarb and ipecac in a pill will be useful Preparation of iron, carbonate of iron with conium etc. muriate of [illegible] 3 drops or 6 and barytes in [illegible] you give a teaspoonful iodine scrophularia mar. [Cistus] Canadensis uva ursi Mr Daggett Havanna Dublin Eliza Collis Vide p. 209 Iron no prep. perhaps are better than myrrh mixture or Jenkins’ pills (carb. per. [illegible] camph.) “Bark & quinine” Different preparations of [illegible] & barytes # Now superseded by iodine. I have seen more powerful affects produced by 4 dr. tinct. iod. persevered in a long “5 to 20 gtts within the year 2-3 gtts ter in die” Various vegetable articles I think very highly Rock rose or Cistus Can. (Helia [illegible] [pity] it is changed) Some years since a person went to Long Island to be cured of scrofula to a family famous for curing scrofula returned much benefitted should his remedies they [illegible] [illegible] & [illegible] always used than afterwards, when [illegible] [illegible] from Havan. neck filled up cured by [illegible] had been salivated W. I. without benefit Eliza Collis scrofulous cough much [illegible] cured by [cistis] vide p. 209. Scroph. maril. has been popular has been much used by empirics I have seen it sold at a great price brought from the west a very common plant It has been celebrated for accelerating parturition probably with out foundation The article has probably little or no power. Yet it is advantageous to know such articles in order to [illegible] [illegible] Two entirely different diseases but are classed together and may be treated together “H. externus is correctly named hydrocephalus” “No fever ordinarily attends. The disease consists in loss of town in the absorbents” Of late iodine has been recommended [illegible] two years since I was called to a patient with had enormously distended [illegible] [upon] gr. cal. & 2 drops tinct. iod. [illegible] recovered Tinct. canth. Face pale and bloated child sleepy and [illegible] I know one child who recovered, but at at the ages of 5 or 6 years died of H. internus. If the patient recovers he is more liable to the acute disease afterwards. Puncturing the membrane has been tried with success, and the application of bandages then supporting the child. It is said that puncturing of the pressure has [illegible] 164 Hydrocephalus Divided into two species externus and internus In H. externus the water is formed between the membranes of the brain (between the brain and its membranes?) In H. internus it is in the ventricles of the brain H. externus make its appearance at birth and is usually born with the child. # In its ordinary form it is fatal (It is almost always fatal when it makes its appearance immediately after birth and always so if born with the child) Stimulating and discutient applications to the head have been recommended. Epispastics are said to be serviceable. (Blisters have been found serviceable they should be kept up for a length of time) Mild mercurials cal. or blue pill & the muriate of lime or sometimes [illegible] pressure by bandaging . If the disease is accompanied by rickets the cold bath is indicated and has been found serviceable I have known one child recover from this disease and other who has been mending under medical treatment for 2 years past. I do not know whether it recovered # H. externus appears to be nearly allied to those watery tumours which affect the spine. In consequence of a partial opening of the sutures of the cranium, or the absence of a portion of one of the bones the dura mater and scalp are protruded by the pressure of the contained water & form a swelling on the outside of the head. Puncturing this tumour is suddenly fatal (is as fatal as the same operation performed on the tumor of the spine. Arachnoid inflammation, arachnitis, apoplexia hydrocephalica (Cullen) encephalitis phrenicula of Rush cephalitis profundu of Good We might multiply [illegible] but perhaps this is sufficient The disease different in different cases A great deal has been written and great deal of confusion exists “In this species of hydrocephalus the effusion of serum is into the ventricles of the brain. This serous effusion is the effect of the disease and not the disease itself & hence it may follow diseases of various kinds. I consider the name very improper” # “The vomiting if it cannot be ascribed to improper food in the stomach is an important symptom in the diagnosis” 165 Hydrocephalus Internus acutus Under this unfortunate name I propose to treat of all those cephalic diseases which are less violent in their action than phrenitis (or are less inflammatory). I shall principally confine myself to the disease as it appears in children “Symptoms different in different cases” The disease commences with the following symptoms (one form of the disease is well described by Dr Quin) vide [illegible] vol 2 p. 315 The patient is languid inactive and drowsy more or less feverish at times apparently free from any complaint (drowsy & peevish at intervals easy and apparently free from any complaint) The appetite is poor and irregular (week) & (Nausea &) in many cases vomiting # occurs once or twice a day. The skin “Exacerbation towards [illegible]” is generally hot and dry (towards evening) and if a perspiration occurs it is partial. Soon after these symptoms. The patient is troubled with a headach. The seat of the pain varies in different cases, sometimes it is confined to one side of the head (Soon after these symptoms commence the patient is affected with a sharp headach either in the fore part or crown) It is a common observation that the headache alternates with the affection of the stomach, the vomiting being less troublesome when the pain in the head is most violent. The pain occasionally attacks other parts of the body (& sometimes principally confined to the back of the neck and the space between the scapulae) At this period the patient is averse to the light, cries much & sleeps little While asleep the patient shows # “The tongue is commonly clean & in this respect this aff. differs from remittent bilious fever, in which the vomiting & febricula are attended with a yellow fur upon the tongue” One side of the face body one arm or one leg more affected or moved often is perhaps a severe a pathogen sump. as any other. This is an indication of paralysis I have known [illegible] patient recover from paralysis 166 signs of uneasiness grating grinding the teeth. starting and screaming in sleep as if terrified. The bowels are usually constipated though sometimes relaxed. The pulse in this early stage does not indicate much danger (These symptoms however are subject to great variations). These symptoms are succeeded by affections of the eyes. One eye is turned in ward to the nose its pupil is dilated The pupil contracted in this early & dilated in the latter stages. Sometimes both eyes at the same time are affected in this way both turned inwards & both pupils dilated. In this stage the vomiting becomes more constant and the headache more excruciating, the pulse is frequent and the breathing quick. # If these symptoms supervene to typhus fever, the pulse becomes more slow Exacerbations of fever take place towards evening. There is often a flush upon one cheek (flushing is usually confined to one cheek) Perspiration if it appears is usually confined to the head and chest. A discharge of blood from the nose at this time relieves the symptoms of fever (& removes the flush from the cheek) for a time & any favorable symptoms. Delirium often takes place at this time and is violent in proportion to the age of the patient All this time the disease is undergoing a change. As the disease advances the pulse becomes more slow and unequal & the patient becomes less sensible to (the pain in the head) his sufferings Lethargy succeeds the disturbed sleep and restlessness of the early part of the disease. The strabismus and dilatation of the pupils increase & the eye loses its sensibility Loss of vision (The patient after sleeps with one or both eyes half closed) The patient in this stage often takes medicine & # “Even in this stage patients have been cured by the strong impression on the system made by tartar em. pushed so far as to produce colic” vide infra Sometimes when hemiplegia takes place the disease puts on a chronic form In the 167 sometimes food will sometimes however he obstinately refuses to take any thing. The bowels for the most part continue costive. # To these symptoms succeed a quick small pulse (almost imperceptible) bad symptoms in the last stage sure forerunners of a speedy dissolution (a difficulty of breathing in many cases the flushing of the face is succeeded by extreme paleness sometimes in this stage petechial eruptions appear on various parts of the body & the patient dies in convulsions or sometimes a hemiplegia takes place two or three days before death The disease sometimes runs through its stage in 4 or 5 days at other times it requires as many weeks. The dilatation of the pupils in some cases does not take place until the last stages & perhaps sometimes not at all. In all cases the proper treatment should have been pursued before strabismus, blindness or coma takes place, because very little is to be done afterwards. A constant rolling of the head & moving one arm and one leg are among the most important early symptoms which indicate a dangerous affection of the brain) The disease sometimes puts on the form of an intermittent. When the disease has terminated in effusion the case is probably always fatal. much dissatisfaction after existed When an ordinary fever terminated in hydrocephalus thinking that the phys. was mistaken at first “I think this disease is rarely an idiopathic affection. It supervenes upon other diseases & generally depends on disease of the stomach & bowels” The disease when from ext. violence may exist without any [pathognomic] symptom 168 Causes external violence teething worms Other fevers forming a crisis by effusion into the ventricles of the brain. Typh. fev. & dysent. in children terminate in [illegible] I have known more than one instance in which it followed [illegible] of hip joiont This is very rarely an idiopathic affection unless it may be considered so when it arises from external violence Vide L. J Pringle on dis. of [illegible] When it does arise from external violence it rarely puts on the same symptoms or the same appearances after death All the diseases of children from infancy are liable to terminate by hydrocephalus & hence it is important to examine all the symptoms which may indicate a determination to the brain & check the tendency if possible Case A girl 14 years of age, had symptoms of affection of the brain from a fall upon the occiput she complained of pain in her head for two or three months before she died & occasionally had regular epileptic fits [illegible] [mouth] The pain the head was relieved by cupping and epispastics to the head, but she finally died in an epileptic fit On dissection the dura mater under the cranium, where the injury had been received was thickened and the vessels were injected with blood. The ventricles contained half a pint of water. Dropsy in the brain Yet the pat. had no dilatation of pupils etc. The dis. put on the appearance of epilepsy occurring once a month. More common in some families than in others 169 Causes. Hydrocephalus is a disease nearly allied to with scrofula & like that seems to run in families. Delicate children in whom the mental faculties are more early developed are more subject to it. Hence the common observation that the child is [illegible] forward that it will not live long I think persons of a scrofulous habit are more subject to this disease & that of the hip joint When there has been no local injury to the brain, the disease commences with affection of the bowels, or it is a sympathetic affection from disease of the bowels In the progress of bowel complaints in children, the [illegible] and the small veins become turgid. This enlargement of the vessels seems to invite the blood to that part. In consequence of this child may die with symptoms of hydrocephalus, from the turgescence of the vessels, without any effusion into the ventricles In typhus fever, in dysentery and in other bowel complaints of children it is not uncommon for children to die with symptoms of hydrocephalus It is a good symptom in hydro. to have a discharge from the [sch??der???] membrane 170 Diagnosis “In its early stage, this disease is scarcely to be distinguished from remitting fever When from the anxiety of relatives & of the physician, a diagnosis is eagerly desired, the following circumstances may perhaps assist in forming a judgment If there is occasional vomiting, with febricula the tongue at the same time remaining [illegible], there is reason to apprehend that the primary irritation has its seat in the brain and that it will prove a fatal case of hydrocephalus. But if along with the fever and vomiting the tongue is covered with a thick yellow fur, we may hope that the complaint is confined to the digestive organs and that the disease is nothing more than coler or remittent fever.” Ed.reviewer Diagnostic symptoms between idiopathic arachnitis or cerebral fever, and infantile remittent or fever from intestinal irritation choler In cerebral fever the abdomen is flattened, not tumefied but in intestinal fever it is tumefied. In idiopathic cerebral fever the secretions of saliva and that form the schneideran membrane are diminished. Unless complicated with aff. of muc. m. which is rare. In cerebral fever the tip and edges of the tongue are red In intestinal covered with a thick fur. In cerebral fever the pain in the head is severe and excruciating; in fever from intestinal irritation it is obtuse. # the sides of the head, back of the head on the forehead Perhaps a constant rolling of the head & movement of an arm & leg are among the most important symptoms Different opinion ben entertained about the nature of the disease Some have been so anxious about determining the exact nosological nature of it disease as to refrain from prescribing until the first stage has gone by. Prescribe for the symptoms at all events and make up your mind about the nature of the affection as fast as you can. Too much discrimination cannot be exercised & cultivated yet where we cannot determine the exact nature of the disease we had better treat the existing symptoms & the obvious indications # It varies in scrofulous constit. there is no such state It may approximate in some cases And I might cite the opinion of 20 others The [illegible] it is sometimes entonic & sometimes tonic. It more frequently [illegible] determined Why shd not fevers terminate in the brain as well as [illegible] 171 In intestinal fever the patient more frequently directs his hand to the nose & about the face in cerebral puts his hand to his head # In cerebral affections the head is hotter than the abdomen; but if the disease originates from the bowels the abdomen is the hottest. “There in a very few cases seen picking at the nose in cerebral fever but in general the rule holds good” “The state of the bowels is not pathognomic” Dr Beddoes thinks the disease belongs to inflammations & that at an early period he should be inclined to bleed as largely as in pneumonia # Dr Withering observes “in a great many cases if not in all, congestion or slight inflammation are the precursors of aqueous accumulation Dr Rush thinks that instead of being considered an idiopathic dropsy, it should be regarded only as an affect of primary inflammation or congestion of the brain “Dr Rush says” It appears that the disease in its first stage is the effect of causes which produce a less degree of that inflammation which constitutes phrenitis & that its second stage is a less degree of that effusion which produces serous apoplexy of the brain Dr Darwin supposes torpor or inactivity of the absorbent vessels of the brain to be the cause of H. internus Dr Whytt in his treatise on the disease observes that this and every kind of dropsy depends upon the fact that more fluids are thrown out by the exhalants than [illegible] the absorbents take up I chiefly depend upon calomel for a cure if it cause too much evacuation check it with opium There is no evacuation from the brain therefore the disease must be overcome by altering the secretions counterirritation etc. Bleeding with leeches from the temples seems to translate to the surface and give relief vide John Hunter. Case young man apparently as desperate a cure as ever I saw not scrofulous we concluded to try tart. emet. gave it without much weight in about 8 or 16 hours he complained of violent pain ion the bowels and all the symptoms of the head were relieved [illegible] “Irritant to the schneiderian membrane in the last stages are recommended by Dr Malachi Foote of N. Y. in the Med. Rep. for about 1810. Turpenth min. 1 gr. with liquorice 20 grs [apreynum] [myrici] ipecac etc. are the best [stermentatories]” 172 Treatment Evacuants Bleeding general & local cathartics calomel and jalap gamboge Counterirritation local bleeding cupping epispastics behind the ears and to the whole surface of the head Salivation should be induced but cal. often relieves without altering the secretions There has been a difference of opinion as to the application of epispastics to the head. If venesection be indicated they should not be applied until after bleeding. I prefer cupping and blisters to the back of the neck and behind the ears I think some advantage may be derived from applying to the spine ol. orig. ol. capsc. etc. Where considerable entonic action has existed I have cured this disease by giving tartar emetic until colic was produced. give perhaps a grain & continue its exhibition until the symptoms abate # “gr doses every 2 or 3 hours” Sneiderian membrane dry snuff malachi root Irritants applied to the schneiderian membrane have cured the disease in its last stages Rx 1 part turpenth mineral & 10 parts powdered liquorice for a [ster??tatory] Green tea is sometimes given In the progress of the bowel complaints of children the sinuses may become enlarged & a determination of blood [illegible] to the brain and produce symptoms of hydr. I have known pat. apparently die of hyd. & yet upon dissection no water be found in the [ventricles] in this case some say that the water was absorbed in death this is entirely improbably. Certainly many of the symptoms of hydr may be prod. by other causes e.g. excessive doses of narcotics is stramonium belladonna It shd be remarked that many cases supposed to terminate in hydr. in cases of [termination] in volvulus “All the diseases of children are peculiarly liable to terminate in hydrocephalus. Hence the importance of caution on the part of the physician. He should examine all the symptoms to check the first beginning of determination of diseases action to the head V.S. keep the bowels open blisters behind the ears cupping leeches” 173 Hydrocephalus from bowel complaints If in the progress of any of the bowel complaints of children morbid action should be determined to the brain, Epispastics should be applied behind the ears and irritants to the feet Cathartics are useful to obviate this determination. # In some cases perhaps the determination [marise] from nervous irritation. In such cases the tepid bath gives relief “Strong green tea” Some physicians of respectability have in formed one that they have used digitalis in hydrocephalus with very good success. I have not used it myself but should consider more adapted for that form of the disease which arises from irritation, than any other Hydrocephalus from disease of hip joint. Child of Ezra Hotchkiss child of Horace Edwards. “I have known hyd. alternate with disease of hip joint Case Narcotics etc. till suppuration” Afterwards died of hydrocephalus # I have cured a patient by giving him calomel and lemon juice in sufficient quantity to move the bowels. It increases the secretions and improves the tone of the bowels “I have seen a case in which the child fell 8 or 10 feet upon a pavement & broke his skull like a squash shell yet he recovered in 2 weeks and did well. When the fracture is so extensive there is less danger of compression of the brain” The same case? Hyd. from injury by a fall is not common in young children the sutures are not firmly closed (the bones are softer & more yielding)( # He had other severe wounds as a compd fract. of the radius yet he never suffered his head 174 When the disease is produced by violence Depressions of the cranium in children from blows or falls are not of course fatal though dangerous. A child four months old fell head foremost upon the hearth striking upon the vertex. The head was much flattened & the parietal bones bulged out on each side. The child did not suffer much from the injury. The bowels were kept open by mild mercurial purgatives. In these the head assumed very nearly its natural shape. A boy of eight years fell six or eight feet and struck his head against a stone A depression of the cranium was made larger than the bowl of a spoon. He suffered very little inconvenience from the injury # There is less danger when the skull is so much fractured as not to cause pressure upon the brain If a child has received a fall we may apprehend danger from the following circumstances. If the fall has been upon the occiput the brain is more commonly injured than if the face is upon the os frontis. If the child vomits after the fall and is very sleepy there is danger that the brain will suffer. Treatment If the child vomits or is comatose after the fall upon the head and there is no wound that bleeds the patient should lose blood and take a dose of calomel, one or both according to the urgency of the symptoms & the death of the patient. All the exciting causes of fever should be avoided and the patient kept as quiet as maybe. The symptoms should be carefully watched and if at anytime there should appear to be a tendency to an affectation # for local bleeding is as important a general bleeding “[illegible] all causes of irritation, as light noise heat, food. Keep the pat. perfectly quiet” “Apply an epispastic behind the ear, or better upon the injured part.” “Blisters are very useful” “Use counterirritation & the tepid bath” # In torpor of the br. [illegible] al. can excite the latter may excite the former and excessive action in the former may be translated by it act on the latter “Give strong cath. cal. gamboge jalap etc.” “Afterwards give cal. in small doses as an alterative If it causes too much evacuation check it with opium” “In N. Haven we have followed Abernethy’s plan of treating infl. of brain for 40 years” 175 of the brain the patient ought to be bled & leeches or cupped. # The bowels should be opened with calomel and small doses of the same remedy frequently given as an alterative After depletion epispastics may be applied behind the ears and upon the part of the head where the injury was received. There is no outlet to the brain & consequently more evacuants are needed than in most diseases Frequent cathartics are useful as evacuants and also to translate action from the brain # When effusion has taken place the case is probably always fatal Yet I have had a pat. with dil. of pupils, who cont. so & paralytic for months & finally recover Vide p. 200 The treatment consists of local applications A variety are used One of the best is [illegible] zii alc. zi An equally good or a better application is seneka oil but the smell is disagreeable. Cold water is applied but though it relieves the pain and the insupportable itching it is doubtful whether it is of any permanent benefit Basilicon [illegible] [illegible] absorbents to ulcers 176 Chilblains Pernio This is a local affection to which children and old people are most subject. Some are much more liable than others. [illegible] [illegible] more liable. The parts affected are the toes heels fingers, hands face, ears and with ladies who wear short sleeves in winter. It is caused by exposure to extreme cold & to cold & damp air & on the feet, more especially by walking through melting snow. It is most common in the early part of winter This affection should be prevented by avoiding an exposure of the parts to the air, by keeping the hands warm with soft leather gloves & by keeping the feet warm with stockings and shoes The skin of the part affected becomes tumefied and hard & of a deep purple colour, there is a pungent pain in the part accompanied with an insupportable itching; & these are often so great as to prevent the patient from sleeping. If the disease advances, the cuticle breaks and discharges a thin fluid. Sometimes a deep ulcer is formed The treatment for the first stage should consist of stimulating application as if for a burn. I prefer oil of origanum alcohol & seneca oil are good applications. Spirits of turpentine will ordinarily do well, though in some idiosyncrasies it acts as a poison. Cologne water may be applied or alcohol two parts with one of ol. orig. # For the ulcers you may use the oxygenated ointment ointment of red precip. citrine oint. # or apply a plaister Dyachylon or Noel’s Not being able to have any fire on board for some days [illegible] to pain of a neuralgic kind as [illegible] were a toothache One of the best applications is a cataplasm of stramonium seeds give internally opium narcotics & stimulants Apply [illegible] & narcotics Followed by no infl. to supp. etc. 177 Painful affection from cold We sometimes meet with a painful affection of the feet without discoloration, or any other visible mark, which has been brought on by long exposure to cold without freezing. Sailors coming upon our coast from the I. in winter, from a warmer climate are liable to it. The affection may be a very painful one and give great uneasiness both night and day It is relieved by the external application of stramonium & epispastics or rubefacients, and fomentations Cathartics and opium may also be given internally. Singular effect of cold in Wm Daggett Burns are dangerous in proportion to their extent [illegible] young physicians are called to prescribe for burns it is important for them to treat them in the best manner About 30 years ago a great controversy existed in England between those who advocated [stimulating] In recent cases stimulating or exciting applications are the best provided the burn is not very deep. About 30 years since spts turp. were much used. It in some case and these are not very rare Case myself [water] boiled over into my shoe I immediately poured spts tupr upon the stocking then took off the stocking applied a cloth dipped in spts turp. put on a dry stock. & boot rode out of town and suffered My father was a man of florid complex. & thin skin He was burned in n a similar manner Ol. orig. Linseed oil is smooth mixed with limewater alcohol or proof spts good when the skin is [illegible] off Others use camphor Others stramonium in ointment contain what [illegible] when the article s off Carrot poultices etc. exclude the air Cotton does well except when the cuticle is off if it is used then you had better smear it with oil 178 Burns This subject belongs more particularly to surgery, yet as burns occur most frequently among children, and you may be suddenly called in on such an occasion, when it is important that a remedy be speedily applied. I have thought proper to make some remarks on the subject. For the treatment of burns very different modes have been recommended. A long controversy was carried on in one of the English journals with respect to the phlogistic or antiphlogistic treatment, one party being in favour of cold applications in cold water and the other of stimulating ones as spirits of turpentine The truth seems to be that in adults where the injury is not extensive and the powers of life are strong cold applications do well, but they are dangerous for children especially if the injury is extensive. Burns upon the abdomen will not admit of cold application even in adults It is necessary that reaction take place If there be no reaction of the system, no pain, no inflammation the child dies. The cause of its death is the irritation of the nervous system, extended to the stomach, & hence the death is preceded by cold extremities and vomiting Where cold application are proper such applications may be made as scraped potatoes, cloths wrung out in cold water etc. But if it is necessary to produce reaction and inflammatory action stimulating remedies must be used. And we know from experience that these remedies do effect a speedier cure Cold applications may do well if immediately e.g. dip a burnt arm immediately into cold water. But stim. app. are better. I have tried both. Cold applic. very dang. in extensive burns of children Case scarped potatoes no infl. livid appearance of the burn extrem. cold [illegible] death In such cases apply stim. app. & give ether, elix. [illegible] etc. etc. In these cases the child dies of irritation not infl. It seems to be necessary for a regular [course] of continuity of action in infl. & suppuration The best and mildest application as has been proved by experience is petroleum or seneca oil In one case I tried the experiment of applying seneca oil upon one hand & ol. orig. upon another (both being known alike) one hand was easy the whole night the other painful (the burn was a very extensive from the clothes taking fire) In the suppurating stage use 1 part seneca oil & 3 parts cerate These cases are very troublesome to treat In the above case the system was exhausted by the extensive suppuration the bowels had to be kept open & large quantities of opium to be given. I gave columbo bark and various tonics and aromatics Turner’s cerate is a good application chalk may be sprinkled over it In the progress of the suppuration a pale flabby fungus almost like a blister and is difficult to manage I have applied a sol. nit. sil. also nit. sil. & laudanum [illegible] cop. sometimes after these I have succeeded with ac. op. in ointment green basilicon i.e. verdigris ground fine & mixed with basilicon But if you apply only applications after these caustics 179 The reason is that we apply to the part a stimulus less powerful than that which produced the injury and thus render the diminution of the excessive excitement gradual. On this principle holding the injured part near the fire is beneficial Another important indication in the treatment of burns is to exclude the irritation of the external air Hence the popularity of some applications as cotton. sweet oil etc. 1st Of stimulating applications. Spirits of turpentine will answer for a robust and healthy person but not for a slender & feeble one; and it must be remembered that from a peculiar idiosyncracy it is a poison to some persons. In general spirits of turpentine is liable to cause irritation and may be suspended by better articles. Being burnt myself a complete cure was effected without the least appearance of inflammation, by this article but in the case of my father such violent irritation was produced as to oblige him to desist from applying it A common remedy in this town is the oil of the origanum majorarum called burn oil mix ol. orig. zii with ol. oliv. zi or mix it with alcohol or cerate. Cloths may be dipped in the diluted oil and kept constantly applied Of late years I have used seneca oil and prefer it to either of the two already mentioned. In several cases I have tried both this and the ol orig. & found that the seneca oil relieved more speedily & with less irritation. I usually apply the seneca oil & the fungus [illegible] Apply rather chalk or fine alabaster or scorched flour The sooner you apply stim. appl. the better ol. turp. produces [illegible] etc. seneca oil does not Case a woman thief etc. etc. we rolled immediately in the snow was thrown by it into a state of syncope life almost extinguished was burnt universally except on the legs covered by the stockings was wrapped in sheets dipped in a mixture of ol. orig. & spirits 180 then cover the part with cotton to exclude the air. I let them remain till suppuration takes place, particularly if the skin is broken. When suppuration takes place, apply a poultice to the loose dressings and then apply simple cerate or a cerate made by melting together beeswax and lard and stirring in seneca oil while the mixture is cooling This last is an admirable application for burns Dr [Mons??] said he knew none so wild. It protects the raw surface from the cold air and keeps in the animal heat In the latter stages of the cure, the oxygenated ointment will be a soothing application A popular remedy is stramonium, used in the form of a plaister of the seeds or leaves. It answers well and I have known no ill consequences to happen from its use though it is said that in extensive burns it is dangerous Cotton is a popular application, used by itself For slight burns it will answer but if they are so extensive that suppuration is to take place, it should not be applied in this way Other remedies that are useful upon the principle of excluding the air, are the oils as sweet oil & lamp oil. Linseed oil mixed with one third part lime water, is especially recommended When suppuration takes place and the cicatrices do not form well, oily application should be laid aside and if there is considerable discharge apply absorbents, as plaister of paris, chalk & chalk & cerate i.e. apply chalk first & cover with cerate. Note from Dr Woodward of Wethersfield extracted from Dr A. Talcotts notes “Apply immediately spts turpentine to the inflamed parts and cerate of limewater & linseed oil equal parts on cotton to the vesications 2nd If pain & irritation ointment of stramonium 3d To prevent fungus Rx white lead a teaspoonful lard 2 tablespnfl. ft. ung. Orgrate or chalk and apply simple cerate over it. I have seen a metastasis at the end of a week to the bowels with diarrhoea & tumefaction or the bronchia with croup Treat with opium & bark Dr S. B. Woodward” N. B. I extracted this principally on account of the definite direction about the difficult treatment required according on the burned part is vesicated or not a point on which the above notes of DR Ives do not seem to be sufficiently precise 181 Should there be a fetid discharge from the burn, it may be remedied by pulverised charcoal. Sometimes the ulcers are very difficult to heal and repeatedly break out afresh A fungus may arise upon the part if so it should be touched with caustic. The eager of the ulcers may be touched with sulph. copper or nit. sil. chalk then applied and the whole covered with cerate. If the burn is on parts liable to unite in healing, as between the fingers and toes, care should be taken to prevent the union. A bad cicatrix is often formed which it is difficult to prevent or cure. Internal Treat When the constitution has received a severe shock and the extremities become cold and the powers of life being to fail, the system must be supported by stimulants & cordials & the excessive irritation relieved by opiates. Laudanum ammonia, spirits, alcohol ether are all good. To a child from 5 to 10 years old 15 drops of laudanum may be given; warm-applications may be made & warm aromatics drinks as ginger tea & mint water administered. Elixir paregoric is one of the best preparations of opium in such cases In a case in which a large quantity of sulphuric acid had been drunk by a boy who immediately afterward, ran to a brook and drank of the water. I merely give mild mucilaginous drinks & the patient being of a strong constitution recovered 182 Croup from p. 138 In what may seem to be the second type of patient may go off suddenly. If he throw his head back in order to enlarge the chest it is a bad sign I have found the treat. by tart. ant. so infallible in the first stage & in general so useful that I have not been tempted to desert it. If I am called rather late and find ext. ant. acting locally upon the stomach, I seldom succeed in curing the patient. Other emetics may be used when the excitability is worm out for [illegible] Calomel is proper in the latter stages, [illegible] the disease is partly broke up by antimony If the first stage is not interrupted [illegible] the child may be playful between the paroxysms and though the pulse is not affected, yet the second will surely come on In the second stage bleeding is to be first resorted to in order to prepare for emetics bleed even to fainting conjoining the warm bath for the same etc. Exciting and irritability [illegible] in this second stage do mischief. I have seen sanguinaria do much mischief. Even after bleeding purges is not advisable for as has been remarked there is a constant tendency in the system to the return of this inflammatory symptom Cal. may be given though if it act by the bowels it will be useless. I have seen bleeding and the vapour bath palliate the symptoms. Scarcely ever will the patient recover 183 Croup In the latter part of the last stage the child throws its head back. This is a dangerous symptom. Now the patient goes into the last or suffocating stage. The patient lies on its back struggles violently for breath countenance livid appears apoplectic and often goes into convulsions and in these convulsions sometimes dies Sometimes in this stage you may hear a flapping of the false membrane. This is sometimes thrown up and great relief is afforded and the friends think that all is over. Soon however in most even of those cases a membrane is formed lower down & the patient ultimately dies In this stage the metallic emetics have in a few cases succeeded The sulph. cupri & the sulph. zinc have each cured Cal. is recommended & may be used The cold both has been recommended It may be tried as a dernier resort. In the second stage after bleeding blisters shd be applied over the whole neck & chest Dr Hosack recommends bleeding from the back of the hand immersed in warm water After bleeding has succeeded in subduing the symptoms cal. & the warm bath shd be used 184 Croup This disease has been divided into acute & chronic but without much propriety Sometimes it continues for some time. I have known one case which continued 3 or 4 weeks In some seasons a different mode o f practice is better. I have known seasons in which cath. & diaph. were the best treatment Although for the first 15 years of my practice I considered nothing more unfortunate than to find the child under the operation of a cathartic. In these cases, it was the form in which the duodenum is also affected in a similar manner Case Wallingford [emet.] failed & cal. & diaph [illegible] Others that season occurred which required the same treatment Bronchotomy has been recommended I have seen it performed but never with success It has sometimes succeeded But in the cases which I saw the membrane form lower down, and the patient die 186 You will see by looking into the throat the tonsils perhaps red & the epiglottis certainly inflamed 187 Angina Laryngia Another form of the croup has been called angina laryngia [illegible] the croup you can see nothing by looking into the throat In this the epiglottis & the [illegible] glottidis are affected From the larynx being affected, the actions & more spasmodic Frequently comes on while eating Case of my child While apparently well was taken while eating with the peculiar croup & respiration of croup & became alarmed & treated This is the form which attacks old people probably Geo. Wash. died of it Case The first time I saw this disease the pat. had had pneumonia & may nearly recover when he went into the cold open air without stockings. I was informed that he was taken with difficult respir. & without seeing him prescribed seneka injurious ultimately refused to swallow anything as the act brought on a spasm I tried bleeding, blisters, vapour & after awhile persuaded him to swallow when I gave him 4 gr. tart. ant. in a cable spoonful of water 188 Angina Laryngea The dis. is brought on by eating And if you examine the throat you will see a redness perhaps upon the tonsils, and will certainly see the epiglottis inflamed Bronchotomy promises more in this form of croup Readily distinguished for the other by difficult deglutition paroxysms being brought on by an attempt to swallow This firm It is not of much consequence to distinguish the forms except that laryngea is more rapid And you must avoid acrids in this form as they irritate the fauces & produce spasmodic action For the spasmodic symptoms give in the latter stages of it asafoetida which also acts upon the secretion tinct. ant. & opium It must be remembered that this disease cannot be cured by bleeding alone. It is too far out of the circulation. But by reducing the system very 189 Croup concluded When croup follows other diseases it is more rapid and dangerous they are very apt to die particularly when following ulcerated sore throat You may treat by emetics blisters metallic emetics etc. but you have not so much strength left in the system to act upon In the latter stage where we wish to throw up the membrane the stomach may lose its excitability to a particular emetic then you are to change the em. I have succeeded in throwing up Upon dissection a membrane is found formed But sometimes it is wanting and in A laryngea then probably is not [time] for a membrane to form Vide p. 211 low and suspending the functions you may change the secretions perhaps 190 191 Scarlet Fever Withering in his first edition separated ulcerated sore throat from scarlet fever. In the second he changed his opinion Where there is much heat and fullness of the pulse I would much prefer a strong dose of cal. followed by antimonials [to] commencing with emetics Or is Dr Rush & the elder DR Barton thought best turpeth mineral Epispastics are to be used with caution & adopted this rule viz to apply them where there is much tumefaction [illegible] & enlargement approaching the quinsy. Scarlet fever after resembling quinsy and is with difficulty distinguished except from the previous affections of the family and neighborhood Mineral acids have been considered specifics Chlorine was much used in this town in [1801] etc. as a fumigator. You may give it internally with advantage A great variety of gargles are used generally stimulating ones are better as those of capsicum (with salt say in cider water) In some cases capsicum does not do well If the patient is too weak to gargle use a syringe 192 Scarlet Fever Chlorate of potash was used with advantage to quiet the stomach. It allayed irritation etc. Ammonia and amm. with camphor & gum arabic In the progress of the disease mineral emetics, as sulphate zinc will be useful to excite the system acting speedily they do not exhaust sul. zinc 5 to 20 grs mosely’s solution was the form most used Sulph. copper 2 to 5 gr. also as an emetic Acetate of copper was formerly kept as a nostrum in some families ½ to 1 t. sp. of sat. sol. of common verdigris 2 to 3 gr. In some cases and seasons cath. are required. I have treated children without a single cath & yet in the same family I have given ant. followed by cal. & worked off by salts and senna If a diarrhoea occurs early it must be attended to white decoction 193 Scarlet Fever Dr With. lays great [illegible] upon diuretics particularly senega giving it throughout the disease. In moderate fevers diuretics eliminate morbid action will Serpentaria may be given freely throughout the disease adding bark alcohol ether or wine Diuretics & diaphoretics Irritable state of the stomach is to be counteracted by irritants by aromatics white decoction etc. etc. a little alcohol upon the fauces voiding a great bulk of liquid Case of a boy in delirium his father was forcing down articles which he was puking up I put into his mouth spoon dipped in brandy 20 or 30 drops his eyes opened immediately said it was good continued it in tspfl doses through the night saved his life Scarlet fever occasionally passed by insensible gradations into quinsy and is of an inflammatory character. No one character will distinguish them No one mode of practice will answer in all cases though if any indiscriminate mode of practice is to be followed that by emetics and stimulants will be best In many cases no evacuations at all are to be used if this you must judge by the symptoms In the same family I have lately treated one or two patients with antimonial and nitre and another who had been worn down by fatigue and watching with feeble pulses vomiting coldness etc. was treated by external heat, brandy in moderate 194 Scarlet Fever quantities, counterirritants spiced tea etc. to stop the vomiting # (One of the best articles in fevers of a low grade is spiced tea or hot spiced wine or brandy. The strength is apt to give out first, and an excitement kept up in the mucous membrane of the stomach will have a beneficial effect) # The first patients in this family I had evacuated freely both by vom. & purging etc. while this patient had no evacuation goodness & was supported throughout the whole progress of the disease After I had seen the disease in 3 or 4 epidemics I thought I had seen the disease in all its forms but I found oftenwards that I met with different forms still Not only different epidemics differ, but different cases during the same epidemic may require widely different treatment In the malignant epidemic of ’94 I was informed by some physicians that they met with cases in which there was increased action though the many cases of the epidemic ran rapidly in the [illegible] gangrenous state In 1803 we generally gave emetics It is said that in the malignant form the eruption is a bad symptom. I do not think so. I think it better for a general eruption to come out the action is less unequal than if a scanty or no eruption appears I hesitated in 1803 much about the application of blisters & I finally found that the rule was a safe and beneficial one to apply them where there was swelling of the tonsils In this epidemic I gave bark, the mineral acids, alcohol, wine, and (for the first time) tinct. canth Tinct. cant. [illegible] zi to pt. give 20 gtts once in 2 hours ½ as much to a child 195 In many cases [illegible] requires to be qualified & corrected by serpentaria or carb. amm. If wine injures the stomach and [illegible] too locally continue carb. amm. which will render it diffusible with white vinegar will have somewhat of an effervescing mixture Use also effervescing mixtures, as soda water, with brandy or ether, or aromatics tincture. It is no objection that you thus combine stimulants and refrigerants, for you thus get diffusible action and obviate unequal excitement. The min. acids may be given in form of punch The sugar will be grateful & useful A diarrhoea is apt to take place in the commencement of the disease. Use white decoction laudanum & injections of starch & laudanum RX starch 3 bal. sp. SS. 30 gtts to 2 t.sp. Pay great attention to cleanliness of the patient Where there is fainting apply ammonia and ether & spirits at the nostrils keep them applied to the nostrils to prevent fainting, I have never known any injury done by over excitement by these articles thus applied Capsicum is used in tropical [illegible] in very strong decoction. Salts and vinegar has been much used as an antiseptic gargle? For the diarrhoea use tonics, bark, contrayerva has been though valuable. Avoid injuring the stomach by distention 196 A variety of garbles (or injections by a small syringe) are used. [illegible] rosemary has been thought a specific & carried hundreds of miles into the country Use others when pat. is disgusted with one # Sulph. cop. ac. cop. nit. sil. ([touched]) apply these with a swab What is called the leathery inflammation is sometimes met with. in which the skin dies at first and afterwards comes off & then a discharge follows. This affection sometimes extends down the throat. In such cases apply blisters to the sternum Touch the part with nit. sil. in such cases. IN one of these the blister on the sternum produced an ulcer which was 3 mo. in healing and in another though the affection with throat was relieved the ulcer for the blister destroyed the little patient # [illegible] oak bark etc. pomegranate combine brandy aromatics etc. It might to be remembered that in the latter stages of ulcerated sore throat where there is an accumulation of [many] a phagedenic ulcer, emetics of sulph. zinc give tone and excite action also when Acetate copper in the latter stages used in an emetic as a tonic or locally applied as a caustic When the stomach fails in the latter stages we give capsicum in pill or strong infusion (2 tab. sp. to the pt makes a strong infusion give to an adult a tablespoonful also acrid oils There seems to be an erythematic infl. of the mucous 197 membrane of the stomach hence acrids are indicated to excite action Bark jacket also it seems to have some effect In the latter stages also a cath. will frequently be beneficial an accumulation of feces may exist given mild cath. as castor oil or perhaps a dose of cal. an emetic also may be needed One thing to be guarded against in young children is the supervention of dropsy In 1803 I had 3 cases all the writers considered the disease as one of weak [illegible] action and requiring tonics bark etc. Not successful Bark does not generally do well when there is unequal action I have known in such cases the brain & nervous system apparently much affected I have given in such cases digitalis and cantharides to produce as new excitement and ally this irritation in the nervous system Case related patient very low from a disease digitalis was given and elaterium being advised was given when the patient died upon the second evacuation In general treat these cases with diuretics a moderate use of cath. narcotics & remedies etc. Digitalis is the best narcotic but be cautious giving it to children In ordinary cases of such dropsy a cath. will remove it and frictions & exercise in the open air. Various articles are popular as ol. [mor] [199] [illegible] ol. gaultheria various irritants etc. and to encourage the attendants to persevere in rubbing you may suffer friction to be made with these mere dry friction though probably just as good does not seem to them like giving medicine Various astringents may be 200 Hydrocephalus The management of the pat. is equally important with the medication avoiding in proper diet alternatives of temperature, and all debilitating irritating and exciting agents all the exciting causes of disaster. Sometimes a patient may (after a fall perhaps) continue one two or 3 years not entirely [illegible] and yet not quite sick and finally die of eff. of the brain Sometimes in strumous habits canth. internally may be advantageous Blisters translate action The applications of remedies to the Schneiderian has been thoroughly treated by Dr Malachi [Foot] in the N.Y. Rep. about 20 years ago. The subject has not bee sufficiently attended to Give in the way turpenth wine (mixed with liquorice) verat. vir. apreyn. [illegible] myrica cerifera etc. If a discharge can be excited relief is afforded Salivation can rarely be produced in children In some cases where there is paralysis the acrids and some of the narcotics as strychnos Blisters are applied by some to extreme parts of the body I sometimes change the place of the blister to the back of the neck etc. But the back of 201 ears is more efficacious. It seems to have a grater affect upon the constitution to excite a discharge from this part If the symptoms indicate bleeding bleed leech also. If there is much infl. about the mouth scarify the gums as a depleting measure “In grade of action the fever of hydroceph may vary from high entonic inflammation or phrenitis to low strumous fever. If the action is too high or too low counterirritation will fall in with the morbid action We must first bring it to the “blistering point” (Rush) “Blisters to the head are thought by some to be dangerous and the ears or neck preferred” “In irritable cases and scrofulous habits, strong cathartics are hurtful. Give blue pill especially when the bowels are primarily affected. But in entonic phrenetic fever, use the drastic cath. & tart. ant. ut supra after depletion” “Scrophulous predisposed mesenteria glands generally affected the fever analogous to hectic never entonic pulse soft, frequent, quick I have tinct. cantharides with advantage in this variety” [204] Volvulus continued from p. 89:a:1/2 “Cases I was called to a child 2 years old which had symptoms of irritation and was obstinately constipated It had been carried on the belly upon the shoulders of another person Gave a cathartic Ordered an injection but the attendant said it would not [illegible] The cathartic was thrown up patient died Upon examination after death no color could be found. In the upper [illegible] rectum there was a tumor which seemed of solid flesh as large as the doubled fist inflamed. The color had been completely removed from its place” “I was called to another family where the children had died when 5 or 6 months old as was supposed of an affection of the brain. This child appeared well when born but was very costive etc. Upon p.m. [illegible] 2 inches of the small intestine were found contracted to the size of a goose quill the coats were thickened & the course the cavity must have been extremely small This contraction undoubtedly existed at birth. This contracted part was received into the part below it, and no [illegible] could have availed” from p. 99 ½ “In another family they had lost all their children at about such an age. They supposed the disease to be hydrocephalus. The older physicians called it so. I told them I could not tell what the disease was but it was not hydrocephalus I had then seen no case of volvulus. There were strong 205 marks of irritation the face was pale and much distress was depicted with countenance the head was rolled back and hands tossed violently. There was vomiting and tenesmus and a discharge of mucus streaked with blood Cathartics had been given under the impression that the disease was an affection of the head The cathartics aggravated the disease which ran a rapid course and the child died. The small intestine was found received into itself and its cavity obliterated. This obliteration of the cavity would not of itself cause death; for a patient may continue several days with perfect torpor of the bowel. It is the irritation as in cholera morbus which is the immediate cause of death which [illegible] death usually occurs within 24 or 36 hours” “Called to a child one year old constant vomiting stool, mucus streaked with blood Directed mucilaginous injections & fomentations combined with opium Gave opium freely internally 10-15 minims to allay vomiting. The symptoms subsided gradually & in 3 or 4 days the feces passed off without any cathartic” “Was called to an Academical student had given cathartics and they did no good. Called in older physicians. They were in doubt respecting the case and advised not to do any thing as we might do hurt. As I was sitting by his side I heard a motion in his bowels. I noticed that it passed down to a certain point and then stopped. Upon examination I could distinctly feel the involution. I tried injections and some [illegible] of them would stay. Ordered a spermacetic candle with opium upon its extremity to be passed up the rectum and allowed to remain. It was s 206 passed in to the length of 10 inches. The opium allayed irritation and the application by repetition replaced the part & the patient recovered another case cured by a bougie” “Opium by taking off the spasm and restoring the natural function of the bowels may be said to act as a cathartic just as in spasmodic colic” From p. 56 “I have given when I could obtain it, the [resin] of Mandrake podophyllum peltatum It operates kindly, and more certainly than any other article. If the western gentlemen who have so much mandrake and whiskey, would furnish a supply. I think it [will] supersede every other article” “If there is torpor & a stuffing or infarction of the bowels we must use injections to assist cathartics repeating them every 2 or 3 hours. If other cathartics do not operate give castor oil which will promote their operation” “The particular kind of injection is not important and may be left to parents Thoroughwort, camomile, mayweed catnip, dandelion, weak soap suds salt & water a tablespoonful to ½ pint water 207 Continued from p. 57 “The stools resemble meconium. In the progress of the disease they exhibit small pieces of a membrane of a dark green colours, about the size of the petals of peach blossoms floating in a dark green fluid. The membrane of coagulable lymph, resembles that formed in angina trachealis and sometimes as in that disease it is formed in such quantities as to cause obstructions Still in this case it may not destroy life the action of this part not being so immediately essential to life. Stools of this kind sometimes attend the bilious colic of adults. They are an indication that farther evacuation is needed Continue the calomel or combine it with magnesia or soluble tartar, or phosphate of soda or other neutral salts 208 Infantile remittent continued from p. 60 “Cases A child had violent fever gave calomel & cathartics warm bath symptoms abated. In 2 or 3 weeks the regular symptoms of hydrocephalus appeared; & the patient seised in the greatest danger. In a short time these symptoms were relieved by a violent and dangerous attack of thrush The patient was very much exhausted lay several days very low gradually emerged and after a long course recovered. “Case of a small little boy 5 or 6 years of age After 5 or 6 days head affected & became maniacal very irritable and cross swore profanely would bite and strike all who came near him. If any thing was attempted to be administered he would shut his mouth. If his mouth was pried open he would close his throat with his tongue Advised his parents not to trouble him nor notice him to pass by him with drink roasted apples etc. but not to offer him any thing. The first day to he took nothing second day took roasted apples etc. readily but ate too much mania returned, but soon went off & patient recovered” “In one case the pat. took nothing for a length of time. Recovered by use of [even ato] & external applications as aloetic plaisters to the bowels etc.” Scrofula continued from p. 163. “Scrofulous swellings are very difficult to excite to suppuration I have however then poulticed without effect for 2 or 4 months Of late I have disused poultices & have applied blisters as soon as may be to excite invigorate the absorbents and act as discutients. They do not disturb the system. If there is suppuration the relaxed state requires stimulating applications lunar caustic vegetable astringents etc.” “Case of a young act 18 with bad cough swelled neck scrofulous temperament Gave laxatives blue pill afterwards rub & spec. Then gave decoction of [cistus] [canadensis] for several weeks and pat. recovered “ A physician (Smith) on Long Island (from an old recipe) has acquired reputation by the use of cistus canadensis combined with uva ursi at the same time enjoining a strict & spare diet as in dyspepsia” “I have given with cist. canat. 1/8 gr. corr. sub. & also decoct. scroph. maril. which is thought by the vulgar to be a specific It has been sold as a nostrum to facilitate parturition called nerve root.) I think it useful in scrofula” “I have known the comptonia [illegible] folia given internally. It is tonic & has balsamic rpoperties” “The remedies particularly indicated are tonics & deobstruents such as will not produce congestion such as uva ursi cistus scrophuloria contrayerva agrimonia (entire plant or root angostura etc.” Sea bathing is recommended, but if the lungs are affected, it will not be advantageous. A sea voyage to the eastward has been of service the constant motion of the vessel stimulating all the vital organs to healthy action The change of air is beneficial & at a distance from the shore there is no danger of taking cold In chronic complaints attended with a want of vital energy I direct a voyage to the east rather than to the south Croup continued from p. 189 “Vapour bath Inhalation of warm water in a [pour] blow a current of air through hot water upon the pate & by means of a coffee pot with two spouts” “Tobacco or snuff applied to the patient” “Croup is an epidemic disease & of course it will vary at the different periods of its appearance We must take into account the prevailing diathesis I have described the disease as it has usually occurred in my practice” “The proxim. cause of the dis. is a peculiar morbid action translated to the traches for the disease arises from general causes acting on the system. In catarrh diseased action is seated primarily with mucous membrane. The exciting causes of croup act on the surface and with different diathesis the same crises might produce pneumonia, dysentery enteritis or cephalitis “Disease determines to the weaker part as the rod attracts lightning” Rush Water & snow cold damp air a [illegible] & low situation sudden changes as when the wind blows from Canada or the gulf stream are the exciting causes “In the treatment sanguinaria, if given early in strong decoction very freely, so that enough of it shall be given & still it vomits or relieves the symptoms, in very efficient practice adopted by Drs Jared Potter & Kirtland “But if inflammation has taken place & the second stage has arrived seneca and sanguinaria are both too stimulating and I have seen them do hurt sanguinaria is less stimulating than seneka For p. 137 “Some authors state that the disease is entirely inflammatory not regarding the forming stage. If the forming stage is wanting we must rely solely on the antiphlogistic treatment” “This disease has a direct tender eye to death The physician must take it out of the hands of nature” “When croup supervenes upon catarrh as it frequently does of late year the mucous secretion and expectoration usually cease suddenly “When croup follows diseases that prostrate the system powerfully as angina maligna, there is little chance for recovery. The sympathies of the system are broken down and Archimedes can find no fulcrum for his lever” “I used tart. ant. at the commencement of my practice and succeeded with it as well as I could wish I therefore contained it, but only in the early stages & to produce a powerful orgasm. If it acts upon the stomach only it aggravates the disease Other practitioners rely upon different articles & probably with equal success bearing in mind however that a powerful impression must be made Decoct. sang. to prostration & vomiting seneca or lobelia inflam with the same view” “Sulph. copper & zinc & acetate copper useful to assist in the latter stages or when other emetics are worn our. So also hives syrup which is much used at the south.” “For six or 8 years past croup has been occasionally different from the pure inflammatory. It affects the lungs and duodenum& calomel and cathartics are the remedies to overcome this form. The cough is more frequent and loose the paroxysms less distinct there is pain in the epigastrium vomiting & a membrane is formed in the duodenum which passes off. I have called it angina duodenitis. The same year ulcerated sore throat came on with it the slough leathery & like a burn it seems to be intermediate between A. tonsillaris & A. maligna The application of lunar caustic by a pencil or brush would prevent croup Blisters to the throat & chin were useful yet a blister would produce the same action as existed in the throat, forming an ulcer very difficult to heal Slough ¼ in. deep 3 mo. in healing. In one case the blister cured the croup and the ulcer killed the patient It is desirable to translate action to parts less essential to life. Cal. & carth. would translate it to the duodenum Emetics & powerful treatment do hurt here. The vapour bark is good. “Croup sometimes recurs several nights in succession A. Laryngea is more apt to do so” “When crop assumes a chronic form emetics irritate inhalation of vapour blisters opium diaphoretics & expectorants” “In chronic croup the inflammation in erythematic and not membranific. The vapour bark often does wonders Tartrate of sanguinaria in ¼ gr. doses Tinct. hyoscyamus gtts x N.B. Dr Woodwd treat of subacute ([S?bertonic]) & typhoid croup the latter contraindicating tart. em. & requiring sanguin. turp. mer. calom. etc. & sometimes capsicum, ammonia & even perhaps wine & alcohol. “One of the most extraordinary examples on record however of the effect of disease in developing of perceiving a certain class of relations is that of [Zerab] Colburn His history is well known When quite a child in his sixth year, without any previous instruction, he could by mere intuition perceive the relations of numbers with so much readiness and precision, as to solve almost without reflection questions in arithmetic which would require a long calculation to enable others to answer. How he obtained this result he could not tell. The answer seemed to present itself to his mind with the same readiness and conviction of its truth, that the proposition tow and two make four does to us. These facts I saw are well known, but it is not so well known, that this power was the effect of disease. That such was the case I have very little doubt This was the opinion of a very distinguished physician who saw him at the time, and who ascertained that he was then affected with a peculiar nervous disease the same (chorea) which Jane had a few years since. In conversing with Mr Colburn about a year ago I asked him if he retained the power of calculation which he possessed in his childhood. He said no, and attributed the loss to the want of its exercise. But why should exercise sustain a faculty in existence which was spontaneously developed?” “Account of Jane C. Rider the Springfield somnambulist; by S W Belden MD. Springfield 1834” p. 108 “The discovery of Zerah’s power of calculation was purely accidental Zerah not having yet completed his sixth year was overheard by his father, as he repeated to himself in his play, parts of the multiplication table. The father surprised proceeded to examine him & [found] etc.