MIR %\ * l« *T ;« J * :v* SURGEON GENERAL'S OFFICE LIBRARY. Section No. 113, w.n.s.o.o. No. lA.tf.lb S—613 « r* f > * it ■< t, » ' -?.^ 215 < ' < V. « c * ^ ^ > f • => *; < < / -^ 2 € S r <3! DUE LAST DATE MAY 20 1966 it# E THE MODERN PRACTICE OF MIDWIFERY, A COURSE OF LECTURES 23 OBSTETRICS:^ DELIVERED AT ST. MARY'S HOSPITAL, LONDON, WM. TYLER SMITh, M.D., MEMBER OP THE ROYAL COLLEGE OP PHYSICIANS: WITH AN INTRODUCTORY LECTURE ON THE HISTORY OF THE ART OF MIDWIFERY, AND COPIOUS PRACTICAL ANNOTATIONS, B Y AUGUSTUS/K. GARDNER, A.M., M.D., LATE INSTRUCTOR ON OBSTETRICS IN THE N. Y. PREPARATORY SCHOOL OF MEDICINE I AUTHOR OF THE " CAUSES AND CURATIVE TREATMENT OF STERILITY," ETC. Illustrate bg 212 (SngrgHtrgs. SECOND EDITION. u». 1 , "..vW> NEW YORK: ROBERT M. DE WITT, PUBLISHER, 160 & 162 NASSAU STREET. wo. IS5? F.~ no. 6 '> ^8 . iu Kntei.ud Recording to Act of Congress, in the vear 185S, by ROBERT M. DE WITT, In the Clerk's Office of the Distriot Court for the Su.ithdtn District of New York. W. H. Timkis, PiiMer and Slertotyper. n ... , " *»■ »". Alexakder, Binder. TO WALTER CHANNING, M.D., ETC., LATE PROFESSOR OP OBSTETRICS IN THE MEDICAL DEPARTMENT OF HARVARD COLLEGE, BOSTON, MASS., THE EDITOR'S FIRST TEACHER IN THE ART OF MID- WIFERY ; THE LAST OF FOUR BROTHERS, TO ALL OF WHOM HE HAS BEEN INDEBTED FOR INSTRUCTION IN .ESTHETICS, SCIENCE, AND RELIGION, AND TO JOHN W. FRANCIS, M.D., L.L.D., THE DISTINGUISHED ANNOTATOR OF DENMAN's MIDWIFERY, AND THE ACKNOW- LEDGED HEAD OF THE ACCOUCHEURS OF NEW YORK, WHOSE NAME IS PLACED IN THE FRONT OF THIS BOOK, NOT WITH THE EXPECTATION OF t ADDING TO HIS NUMEROUS AND WELL-DESERVED HONORS, BUT TO TESTIFY TO HIS KINDNESS OF HEART, AND ACTIVE PERSONAL FRIENDSHIP, Qt&te ESTork is most rtsptttfulls fcibi'tatefr. EDITOR'S PREFACE. As the Lectures which form the basis of this volume approached completion in the London Lancet, where they first appeared, I was convinced of their superiority, and that if collected into a volume, they would consti- tute the best body of Midwifery extant. Propositions were made for my superintendence of such a work sup- plying any deficiencies, and rendering it as complete as possible—to serve at once as a manual for students and a reference for the practitioner. Accordingly, it was prepared for the press in the fall of 1857, but on account of the financial revulsion, it was deemed expedient to defer its publication till the present summer, and nume- rous editorial additions mark the second revision thus rendered imperative. Finally, when nearly stereotyped, its progress was again arrested by the delayed appear- ance of the London edition with several new chapters and cuts, requiring the work to be torn in pieces, re-paged, etc., in order to place the additions in their appropriate localities. I have thought it best, however, deviating from the English print, to preserve the form of lectures in which they originally appeared. Further than that, it differs little from the author1 's revised edi- tion, except in immaterial expressions and expletives. 8 editor's preface. [ have carefully avoided making any subtractions from the work even when elimination might have been of utility. The additions which have been made, are inclosed in brackets [ ], and will be found mainly to be of a practical nature ; the introductory lecture and lec- ture xxxiv., on the operations upon the os and cervix uteri, being the most extended. I have also endeavored to present some instruments of a less clumsy character than those depicted by the author, the use of which, especially the forceps, would seem, in their own appear- ance, to indicate the reason why they were so little in favor with English obstetricians. For valuable sugges- tions from Drs. T. G. Thomas and Charles A. Budd, the fruit of their experience as acceptable teachers of this branch of medicine, I must acknowledge my obliga- tions. This work is here submitted to the profession, in the hope that as now issued, it may not fall under the general obloquy of American editions of foreign works. Certainly the enterprising publisher has spared no expense in presenting the work in a creditable manner, and no little labor and thought have been bestowed upon it by The Editor. New York, 141 East Thirteenth Street, September, 1858. CONTENTS. ■*► PAGB Preliminary Lecture,..........11 LECTURE I.—Generation............83 II.—The External Organs of Generation,.....48 III.—The Internal Organs of Generation,......62 IV.—Ovulation,...........76 V.—Menstruation,..........85 VI.—Conception, and the Early Development of the Ovum, . . 97 VII.—The Decidua, Chorion, Placenta, and Umbilical Cord, . . 109 VIII.—Signs of Pregnancy,.........127 IX.—Disorders of Pregnancy, . .......149 X.—Disorders of Pregnancy—(continued),......102 XI.—Causes of Abortion,.........177 XII.—Treatment of Abortion,........192 XIII.—Duration of Pregnancy,........210 XIV.—Molar Pregnancy—Blighted Ova,......223 XV.—Super-fcetation—Extra-uterine Gestation—Missed Labor, . 233 XVI.—The Gravid Uterus,.........249 XVII.—The Nervi-Motor Functions of the Uterus, .... 261 XVIII.—The Fcetus in Utero,.........270 XIX.—The Bones, Articulations, and Ligaments of the Female Pelvis, 284 XX.—The Anatomy of the Fcetal Dead,......309 XXI.—The Mechanism of Labor,........321 XXII.—The Mechanism of Labor—(continued),.....336 X CONTENTS. PAQ8 LECTURE XXIII.—The Stages of Labor,........346 XXIV.__The Management of Natural Labor,......357 XXV.—Management of the Puerperal State......374 XXVI.—Presentation of the Face,.......386 XXVIL—Pelvic Presentations,........400 XXVIII.—Transverse Presentations,.......417 XXIX.—Placental Presentation,...... 428 XXX.—Funis Presentations.........458 XXXI.—Deformities of the Pelvis,.......471 XXXII.—Deformities of the Pelvis—(continued), .... 491 XXXIII.—Obstructed Labor,.........505 XXXIV.—Obstructed Labor from Rigidity of the Os Uteri, . . 518 XXXV.—Tardy and Precipitate Labors,......533 XXXVI.—Difficult Labors depending on the State of the Ovum, . 545 XXXVII.—roST-PARTUM Hemorrhage,.......55C XXXVIII.—Rupture of toe Uterus,.......575 XXXIX.—Inversion of the Uterus, etc.,......585 XL.—Puerperal Mania,.........596 XLI.—Puerperal Convulsions,........605 XLII.—Puerperal Fever,.........624 XLIII.—Puerperal Fever—(continued), . . . . . . 634 XLIV.—Phlegmasia Dolens—Puerperal Arteritis—Sudden Death in the Puerperal State,......648 XLV.—The Induction of Premature Labor,.....657 XLVI.—Turning,...........6Gg XLVII.—The Forceps,..........684 XLVIII.—The Caesarian Section,........>jq% XLIX.—Embryotomy,..........i^ L.—Conclusion,..........ijgg A HISTORY OF THE ART OF MIDWIFERY, (Delivered at the N. Y. College of Physicians and Surgeons, Nov. Wth, 1851.) BY A. K. GARDNER. ■***■ PRELIMINARY LECTURE. Before commencing this series of Lectures comprising the whole study of Midwifery, written with great clearness and pre- cision and with a fullness unequalled in any treatise upon this important branch of medicine, it may be well to note the gra- dual advance of the art and science of midwifery (for it has two aspects). Let me therefore beg your attention to a brief epitome of the origin and history of the art and science of obstetrics, from the earliest records down to the present time; and, if in its narration, there be little food for national pride, let us not fail to notice, that in the brief period since America has vied with the nations of the earth in ameliorating human woes, her contribu- tions towards assuaging the pangs of childbirth, equal, if not surpass, all those of the rest of the world—let us not fail in this to see encouragement for the future; and let all strive to rival one another in the double aim of benefiting mankind and exalting the reputation of our beloved country and its medical profession. From the foundation of the world man has been born of woman; and notwithstanding that his inventive genius has dis- covered steam, the great Briareus of the nineteenth century, and harnessed him to his chariot, and sends the lightning to do n 12 FIRST RECORDED PRESENTATION. his bidding over the almost boundless extent of the world, yet we caniiot°hope that any change can be effected in this particu- lar. But, although man's entrance into this world was always in this manner, the art of midwifery was of much more recent origin. That function which it is the aim of the art of mid- wifery to facilitate, may have been effected in the greater num- ber of cases without the intervention of foreign aid, and the women may at an early period have been confined alone; but childbirth has never, probably, in the most favorable climate, and at any time, been always so easy and prompt. Some women have been exposed to great pains and perils. Compas- sion for suffering, a natural pity and a common lot, brought around the sufferers those who had passed through the same trials, ready to assist and counsel. Those who therein showed the most courage and address were sought for at such times, and these were in great demand. Tradition hands down from gene- ration to generation the wisdom of each preceding, and thus, probably, the midwife was created, and a distinct profession arose, devoted to this calling. The first mention that we have of it is, that the ancient Hebrews employed mid wives to assist in the delivery of their children ; and the first two whose names have descended to pos- terity, are Shiprah and Puah, who were exercising their profes- sion at the time when the Hebrews were first in captivity in Egypt, about the period of the birth of Moses. Long preceding that era, however, we have an account of the confinement of Rebecca and the birth of Esau and Jacob. " And the first came out red, all over like an hairy garment, and they called his name Esau; and after that came his brother out, and his hand took hold on Esau's heel." Thus the first recorded pre- sentations were of the head in Esau's case—and of the head and hand in the case of Jacob. Though I have mentioned that the first midwives whose names are given, were at the time of the first captivity in Lgypt>it; is evident that a distinct class of persons were set apart for this office anterior to this period. For we read that - Rachel travailed and had hard labor; and it came to pass that when she was in hard labor, that the midwife said unto her, Fear not, thou shalt have this son also :" and again it is recorded of Tamar, the daughter-in-law of Judah, of whom it RAPID PROPAGATION. 13 is narrated, " that behold twins were in her womb. And it came to pass when she travailed, that the one put out his hand; and the midwife took and bound upon his hand a scarlet thread, saying, this came out first. And it came to pass as he drew back "his hand, that behold, his brother came out ... . And afterwards came out his brother that had the scarlet thread upon his hand." May not this be most probably the first recorded case of spontaneous evolution in an arm presentation ? Rachel is the first case mentioned that died in labor, although from the above quoted remark of the midwife, it would seem to be not an unfreqnent occurrence, or at least that death in labor did sometimes occur. The narration continues to state, " And it came to pass as her soul was in departing (for she died) that she called his name Benoni." Some idea of the character of the assistance afforded by the midwife maybe judged by the remark of Rachel to Jacob, at the time when she was barren : " And she said, behold my maid, Bilhah, go in" unto her, and she shall bear upon my hues, that I may also have children by her." Again in Exodus, where the king of Egypt spake to the Hebrew mid wives, say ino- " And when ye do the office of midwife to the Hebrew women, and see them upon the stools, if it be a son, then shall ye kill him," etc., but as they failed to do so, and the king asking the reason, they replied, " Because the Hebrew women are not as the Egyptain women ; for they are lively, and are delivered ere the midwives come in unto them." It would thus appear that art had endeavored to invent some method for mitigating the sufferings even at this early period, and that the " Portable ladies' solace or Accoucheur's chair," is no new idea. Hippo- crates makes no mention of a chair or any particular form of bed in natural confinement, but in a tardy labor he speaks of their being placed upon a chair with a hole in it, or on an inclining bed. In the fifteenth and sixteenth centuries the mid- wives carried chairs about with them from house to house, and similar ones are still in use in Germany, and are called kreia* stuhl. While speaking of the Bible history of the art of midwifery, it mav not be amiss to mention an instance of the most rapid propagation mentioned in any work. After Joseph was settled as Governor of Egypt and his father had gone with all his house 14 BIBLE HISTORY. to join him, "all the souls of the house of Jacob which came into Egypt were three score and ten," which evidently refers only to°the males—the descendants, excepting the tribe of Levi, were numbered by Moses, the second year after leaving Egypt, which is variously considered to be from 210 years to 430 years. The number at this time was 003,350 fighting men above 20 years of age. A calculation is gone into in the Talmud, which has been very much ridiculed by many. Allowing for the early marriages capable of being contracted in a warm climate, and ordinary length of life, it is found that for this increase it is necessary that there should be six children at a birth. Those believing this have been jeered at, because it was stated that there never was an instance recorded of so many human beings being born at once. But, recently, a woman at Sidney, New South Wales, was delivered of this number, which has proved the thing possible, though none the less miraculous. There is much in the Old Testament upon kindred topics, many laws are laid down to the PentateuA respecting men- struation and its disabilities, purifications therefrom, etc. Its particular reference to Bathsheba is mentioned in 2d Samuel. Barrenness is called " a closing of the womb " instead of "a stricture of the cervix uteri" of the modern nomenclature. Tho period of utero-gestation is stated at nine months, yet in the Book of Wisdom the following remark occurs relative to the term of pregnancy; c' and in my mother's womb was fashioned to be flesh in the time of ten months." These ten months must of necessity be moons or forty weeks or two-hundred and eighty days : a term deemed most precise of the duration of utero-ges- tation. The words " untimely birth " are to be found in several places as in Job and in the Psalms. Labor pains are noticed in several passages. The management of new-born children is but alluded to in Ezekiel. Lactation was much prolonged, for in the apocrypha a woman says to her son, " I who gave thee suck three years." From this period to the birth of Hippocrates, 458 years before the birth of Christ, we have no record of the advance of the art, if any there were. At this period it would appear that nature was but little assisted by art. The practice was in the hands of females without information upon the subject. Yet Plen- arete, the mother of Socrates, was a midwife ; and Plato speaks of HIPPOCRATES ON OBSTETRICS. 15 midwives and explains their functions and regulates their duties. The knowledge of the anatomy of the parts was extremely imperfect, even to the minds of such individuals as Hippocrates and Galen themselves. Conceive, if you can, the books of the world destroyed, schools of medicine abolished, and the prac- tice of midwifery again in the hands of women, even of the intellectual females of the present day, and after the lapse of fifty or a hundred years, imagine its state ! Far worse was its condition 458 years before the birth of Christ. The traditions upon which the midwife of those days relied, were founded upon error, while a century hence the learning of the present day would in some degree be perpetuated. The writings of Hippocrates upon this subject are three trea- tises ; De Natura Muliebri, De Mulierum Morbis, and De Super- fcetione, papers far more profound and embracing a far wider reach than we should suppose probable at this period. His theory of conception and generation was acknowledged, till quite a late period, as correct. According to him conception was a fermentation of the male and female semen, which he believed was elaborated in the brain : the sex depended upon the predo- minant influence of either parent. Like Democritus, Hippo- crates maintained a locomotive power in the uterus, yet in his book, De Natura Pueri, he furnishes us with some interesting cases concerning the ovum and the means by which it may be expelled. He has treated at much length on difficult labors, notices various presentations and different attachments of the placenta. The singular circumstance that a child of seven month's gestation has, according to some, a greater chance of living than one of eight was noticed by him, and he attempts an unsatisfactory explanation of it. (This question is also moted in the Medrash Rabbah, or the exposition of Rabbah on the book of Exodus, a rabbinical treatise dating from the 3d cen- tury. It there states of the mother of Moses, chap. ii. verse 2 : And the woman conceived and bore a son, and when she saw him, that he was a goodly child, she hid him three months." It seems that the executioners of Pharaoh had spies, who noted carefully all the pregnant women among the Hebrews, and cal- culating closely to the date of their delivery, went and took the child away and destroyed it. In order, therefore, that the child could have been concealed three months, it must have been six 16 THE RABBINS ON OBSTETRICS. months and one day old, says the Medrash, for a child can live at seven months and not at eight.) The writings attributed to Hippocrates treat at some length of difficult labors, and notice various presentations of the child, and gives many gen- eral directions. At the time of Hippocrates the physician and surgeon was called upon by the midwife only when the woman was in extre- mis, for the purpose of delivering, by forcible means, the foetus which threatened the life of the mother. If the labor advanced but slowly, Hippocrates advises that the woman be attached to the bed, which should be considerably inclined, and then forci- bly shaken ; snuff to be given, and the nostrils to be closed when sneezing was excited; fumigations and unctions to the genital organs, and excitants of all kinds. In the teachings of Hippocrates, he advises the breaking up of the cranium and the extraction by the hook. He also counsels turning when prac- ticable.—Celsus, who lived at the commencement of the Christ- ian era, says, " If the head present, and the child is supposed to.be dead, that a hook should be placed in the eye, ear, mouth or forehead." The deliverance of the placenta was in those early times effected by the weight of the child, the cord not being cut until this was achieved. If the cord was broken by any accident, weights were attached to the portion in connection with the pla- centa, the woman being on a pierced chair or an inclined bed. Hippocrates objects very strongly to drawing upon the cord, and in order to make the traction as gentle and regular as possi- ble, advises that the child, or the weight before mentioned, be placed upon a leathern bottle filled with water, and punc- tured with a few holes, so that the water slowly escaping, the cord would be gently drawn upon. If this method did not suc- ceed he gave sternutatories, that by the sneezing the placenta be thus detached. It is supposed that hysterotomy is of very ancient date, as it was called euPpioeknr) and voreooTouoTOKie by the Greeks ; these terms are still used by modern writers, but it is generally consi- dered that it was only after the death of the mother that they had recourse to this operation. Indeed, writers upon this sub- ject give the ten successful cases of Rousset, published by him in 1581, and translated into Latin in 1661, as the first cases THE CESARIAN OPERATION. 17 where the operation was performed upon the living woman. He has reported ten successful cases, and one woman who was operated upon six times, and died the seventh, because he could find no one willing to operate. This woman was named Godard, of Milly, in Gatany, and was operated upon by a barber. One of the other women, named Ouinville, was also similarly deliver- ed by a barber, who is reported, perhaps as an excuse for the rashness of the act, to have been drunk at the time. The first authentic and successful case is reported by Michel Doeren, professor at Giessen, and afterwards at Breslau, and who died in 1664, which he saw in 1610, operated upon by Jeremiah Trautman. I am, however, convinced that the Caesarian operation was not confined to cases where the mother had died, but that very long before the period mentioned, it was of not unfrequent occurrence. I have recently been shown in the Jewish Mishnah, a passage on this subject. This very remarkable work is one of the most au- thentic on record. It was handed down by tradition for several hundred years, as is supposed, before the Christian era; but the various articles of the work, which is now called the Mishnah, were not collected and written in Hebrew till a.d. 180. In this most curious work, upon all sorts of topics having any reference, however remote, to the Jewish religion, in the 5th chapter of the treatise " Niddah," section 1st, is the discussion of a law question. It relates to the purification of women after delivery ; and the question is whether a woman is unclean who has had the child cut from her side, " yotza-dophan." This would make it appear that the operation on the living person was of much earlier date than generally supposed, as we would not imagine such a question would be debated, if the fact was not known sometimes to occur. After this period, almost a thousand years passed away with- out leaving a trace of the art, and probably without any improvement. Paul of Egineta, who lived in the seventh cen- tury, and who was perhaps the first man-midwife, coincides with Philomenus, of a somewhat earlier date, that the whole aim was to extract the foetus in any way, and without regard to its life, by turning, the crochet in the fontanelles, or by dismembering the child. Albucasis says the same things of Arabian midwi- fery of the twelfth century, and describes various instruments for compressing and breaking up the head, and others, for jg WONDERS OF THE DARK AGES. extracting it. Among them is a species of forceps with teeth which he terms a " misdach," for the purpose of crushing the head and enabling it to pass; he also gives a plate of a single and dou- ble hook, and a knife for cutting off the head. Ambrose 1 are s work, dated 1579, gives plates of various modifications of the same instruments. From this period, these and similar instruments were in gene- ral use, and more attention seems to have been given to the general subject. Ignorance is always credulous, and it is not to be wondered at, that a great number of ridiculous cases and extraordinary tales have come down to us. Among those most credible are reports of children born in pieces, by the anus, through the abdomen, and by vomiting, which seemed most wonderful to the reporters of those days, but which we now recognize to have been extra-uterine pregnancies. Massa, a Venetian, reports a woman, aged 60, who was supposed to have had dropsv, that was confined, after fifteen months, with a o-irl, without eyes or arms, which defects and delay were attri- buted to her advanced age. Jules Crassus gives several instances of children born after eleven months' pregnancy, but admits that these instances are uncommon. It is evident that from this date more attention was paid to the subject, from the reports of writers more credible; Diomede Cornarus, physician to the Emperor Maximilian II., speaks of deafness having occurred after labor, etc. By the following data the gradual growth of the obstetric art may be seen. Aristotle first notes the importance of the menstrual flux, and affirms that, with very rare exceptions, women are barren who have never menstruated. He also treats of the signs of preg- nancy and divides labors into natural and unnatural. Celsus first recommends " turning " in all cases of unnatural presenta- tion. Pliny considers footling cases unnatural, and thinks that twelve children could be born at a birth. Aristotle's credulity stops at five. Galen seems to have been the first to understand the anatomy of the viscera of the female pelvis. Pliny divides the uterus into the fundus and neck and describes the os tinea? • notices the derangement of the digestive organs attendant upon pregnancy; ascribes to the undue union of the ossa pubis the main cause of difficult parturition. Among the Arabians, Serapion treats upon the disorders inci- INVENTION OF THE FORCEPS'. 19 dent to pregnancy. Rhazes directs how to puncture the mem- branes with the nail or a sharp-pointed instrument when they retard labor. Coming down to brighter days, we arrive at the period when, by the discovery of the vectis, the first impulse was given to midwifery, and from whence its subsequent progress com- menced. Although claimed by many for Celsus, its real disco- very or invention is undoubtedly due to Henry Roonhuysen, of Holland. Although its introduction was of great advantage to the art of that day, this instrument, in its various modified forms, is now scarcely used by practitioners, for, employed as a means of traction, it is far inferior to the forceps, and its origi- nal employment as a lever is so dangerous, that it is very pro- perly in a great degree discarded in actual practice. For a considerable time it was in very common use, and till with- in a few years, there were m'any who spoke very highly of its utility in changing the positions of the head—an alteration which is now very generally believed to be due, oftener to the powers of nature than to the manipulations of the accou- cheur. In the invention of the vectis the forceps were half dis- covered ; for it is supposed that from this hint, Dr. Hugh Cham- berlain, some time before 1647, constructed the original of the various modifications and fashions now in use, each of which is so highly vaunted by its possessor, although a similar instru- ment is described by Avicenna. Judging of the success of physicians of past days, with those of the present, it may well be suspected, that the result depends more upon the skillfulness of the hands which hold the instrument, than upon any peculiar shape or fashion of the iron. Since this time but few instruments have been invented for obstetrical operations: one, the cephalotribe, by Baudelocque, Jr.,—a most formidable but exceedingly useful instrument, which I have seen several times used in the cases of the rickety pelves of Europe, with great success by Professor Dubois. It will I trust, be many years before disease shall be so common in this country as to require its assistance. It is an exceedingly useful instrument. Another instrument is of more recent invention, of this country, I think. It is a revival of an ancient attempt to pass a band over the head for the purpose of traction, and is 20 EARLY OBSTETRIC WRITINGS. called a fillet, if I correctly remember. It will probably never be of any great use. Valuable modifications of various instru- ments are referred to in future pages. About this period the illustrious Harvey, in England, and con- temporaneously the renowned Ambrose Pare, in France, by their genius still farther advanced the art and drew attention to it. Pare wrote largely upon monstrosities both human and compara- tive, giving thirteen causes for them, including divine wrath. He divided labors into riatural and preternatural, classing under the former those cases in which the child presented with the head and was delivered coincidently with the discharge of the waters. The preternatural includes all others, in all which cases he advises turning. Guillimeau, his pupil, records cases of rup- tured uteri under his own observation. Harvey's work De Gencratione gives detailed accounts of expe- riments made under royal patronage with a view to the elucida- tion of the subject of generation. In it he attempts to detect the nature of conception, and follows the daily change in the hen's egg during incubation. His examinations are minute and origi- nal. He discovered that the chick originated from the cicatri- cula of the ovum, and the punctum saliens to be the heart. These and many other investigations entitle him to be mentioned with high respect among those who have advanced the obstetric science. About this time, 1663, the ignorant midwife was supplanted by the man of scientific attainments, as will be hereafter mentioned. In 1640, an essay on foetal life was written by Ny mm anus and a treatise on the diseases of women and children by Sennertus. Mauriceau, in 1666, gave to the world his system of midwifery, more ample in its details and richer in practical information than any preceding work. It was translated into English and published by the Chamberlains. From the general introduction of the forceps into obstetric practice about the year 1700, one very happy result was achieved. Previous to this time physicians, as I have before said, were only called to women in labor to correct the blun- ders committed by the ignorant women in attendance, and as this was generally after hope itself had almost fled, he was gene- rally considered as the messenger of death. But the preten- tions of the possessors of this new instrument to greatly abridge EARLY OBSTETRIC TEACHINGS. 21 the duration of labor when it was natural, and to save life when difficult, changed the habits of the people. Every woman almost, was delivered with the forceps. The consequence was, that the theoretical knowledge of the physician soon became practical; what had been for so long mere chance, quickly advanced to the dignity of an art. Vigorous and educated minds began to be interested about it; labors were classified and instruments were used only in cases especially requiring them. Nature was no longer interfered with, but assisted when her powers failed. The mechanism of labor then first began to be understood. Previous to this period it was supposed that the child during utero-gestation retained a sitting position in its mother's womb, and that a short time before confinement, it therein turned a somerset in order to bring the head in the usual position for delivery. Astruc thus describes this prevalent opinion : " In this state, the infant has his head upwards and his feet towards the orifice of the uterus, with his face towards his mother's abdomen. During the first six months he remains in this situation, his head being towards his mother's navel, for his feet are, during that time, specifically heavier than the head ; but this part begins at length to grow faster, in proportion, than any other ; wherefore, its superior weight turns the head downwards towards the ori- fice of the uterus, just as we see a ball of lead joined to a piece of cork, by its specifical weight to sink, whilst the cork floats on the surface, or keeps the superior parts. This change of situation of the infant is owing to the speedy growth of the brain. He is thus turned about fifteen days or three weeks before the delivery, which the inidwives, nay, the mothers, per- ceive at that time, wherefore they say that the belly has then fallen." It was then supposed to present, with the long diameter of the head to the short diameter of the pelvis, either the occiput or sinciput to the sacrum. Sir Fielding Ould was the first writer who corrected this latter opinion, and stated that the face was turned in the first part of its progress to one side or the other of the pelvis, "so as to have the chin directly on one of the shoulders." Dr. Smellie, in 1752, began to teach in England. It is reported of him that he had at his door a paper lantern placed, upon which was written, " Midwifery taught here for 22 OBSTETRICS TAUGUT IN AMERICA. five shillings." He corrected the error of the twisting of the neck, but generally agreed with Ould. He also contributed materially to the mechanical improve- ment of instruments, was the first who accurately determined the shape and size of the pelvis, and the head of the foetus, and pointed out the whole progress of parturition. From this period, general attention was given by the profes- sion to the study of midwifery. The art was regularly intro- duced as a branch of education in the medical schools. Nume- rious establishments were devoted to practical instruction of students in surgery and mid wives. The illustrious Ruysch of Holland, prepared two cabinets of preserved foetuses of all ages, sizes and conditions (afterwards sold to Russia) perhaps never equalled. By his writings and labors he greatly^ advanced the science. Maubray, 1723, was the first teacher of the science in England, and opposed the use of instruments. Dioneis reports cases of ruptured uteri. Gregory the younger, gave a course of instruction in Paris in 1733, he gave the first correct idea of the nature of retroversion of the uterus. Manningham a simi- lar course, and a clinique at his own house in London at the same time, having established the first hospital for lying-in women in England. De Lapeyronie, first surgeon to Louis XV., created two chairs for obstetric teaching, one for sages- femmes and one in the college of surgery. The faculty of medicine instituted a similar chair. In 1697, Van Hoorn in Sweden, established a similar professorship for midwives at Stockholm. In 1737, a hospital and practical school was established at Strasbourg, the first institution of the kind created for students. Similar institutions were established all over Europe, and among them in Rome, in 1789, by Pope Pius VI. and in St. Petersburg, in 1797, by the Empress Federowna. The publication of Dr. William Hunter's great work on the gravid uterus in 1775 forms an era in our science. It is unsur- passed in the accuracy of its drawings and the style of their delineation at the present day. In it he portrays the membrana decidua and reflexa which are his own discoveries. Not behindhand in the march of improvement, Dr. Shippen of of Philadelphia, pupil of Dr. W. Hunter, first gave public -e year 1762. ret class often pupils increased to two hundred and fifty instruction in midwifery in the New World in the vear 1762 PROPOSITION OF SYMPHYSIOTOMY. 23 before his death. In 1767, the medical school in New York, under the direction of King's, now Columbia College, was founded with Dr. V. B. Tennant, professor of obstetrics. In 1756, the subject of the induction of premature labor as a substitute for craniotomy, the csesarian section and other similar subsequent dangerous operations, was first made a matter of discussion. The usefulness of the operation was soon allowed, but the mortality soon rendered the matter a questio vexata, not only for the physicians, but for the D.D.'s of the Sorbonne. It is curious to see how similar questions were frequent stumbling-blocks in the schools of France, where a very large majority of the children under discussion were generated in immorality, and then to observe with what clearness the great English teachers, Denman, Clarke, Burns, and others, have investigated these apparently similar questions. Whatever may have been the queries, no objections are now urged against this operation, which is occasionally practised by all the celebrated accoucheurs of the present time. In the year 1768 the plan of dividing the ossa pubis was pro- posed by Sigault, of France, for the purpose of increasing the antero-posterior diameter, and thus safely delivering the child. It is astonishing with what enthusiasm this operation, now every- where reprobated, was received by the profession throughout the world, and more particularly in France. Calm investigation was out of the question, and the operator and inventor were everywhere received with the most distinguished honors. Not- withstanding that the patient, who had previously been deliv- ered by craniotomy, barely escaped with her life, and received a serious injury of the bladder, on the strength of this one case the medical faculty of Paris voted medals to Sigault and his assistant Le Roi, and a pension to the former and his unfortunate patient. In no future case was the success equal to this, the first. " Every operation had its victim," says Hull, " not- withstanding it was sometimes performed upon women whose pelves were slightly deformed, and had previously been delivered without extraordinary assistance." In England, this plan was first seriously examined by the Hunters and Dr. Denman, who reported against it. Indeed, subsequent examination has proved that the division of the ossa pubis does not sensibly enlarge the antero-posterior diameter, and the whole matter seems to have 24 CLASSIFICATION OF OBSTETRIC PRESENTATIONS. been verv much like the question once proposed to a learned academy, and long and profoundly debated by them, why a bowl filled to its utmost capacity with water would yet admit a fish to be placed therein without displacing its contents. Symphy- siotomy has, however, done one good thing. It has taught the profession to be certain of facts, and to reason upon them, and act, also, afterwards. Has the lesson been received ? or is every new theory and medicine—homoeopathy or cod liver oil— received as soon as promulgated ? A somewhat similar operation, called not after its inventor, but by its reviver in 1829, is Catolica's operation, which differs from symphysiotomy in not dividing the cartilage, but the body and ramus of the pubes on each side between the two foramina ovales, as was recommended by Aitken in 1785. A more scientific appellation would be bi-pubiotomy, were a name desirable for an operation which is not recommended by a single successful result. While these foolish proceedings were being enacted, there were some attending to the true interests of the art, and by a curious coincidence, Saxtroph, of Copenhagen, and Solayres de Renhac, of Montpelier, in 1771, published each an essay which agreed in the assertion, that the long diameter of the head, con- trary to all previous teachings, entered the pelvis parallel to one of its oblique diameters, the sagittal suture running in a line from the sacro-iliac synchondrosis behind to the foramen ovale in front and generally from the right sacro-iliac synchondrosis to the left foramen ovale. From this small beginning have proceeded those improve- ments in midwifery which have rescued it from empiricism, and almost transformed an art into a science. Baudelocque, in the year 1791, methodically arranged the posi- tions and presentations of the child, making twenty-two presen- tations and seventy-four positions. This classification, modified as ,t has been by various subsequent writers, among them and the most conspicuous, Naegele of Heidelberg, is at the bottom of the present system of teaching throughout the world No prac titioner who pretends to science at the present day, denie the great importance of a knowledge of the position, as well a he part presenting. All operations are based upon this know die for as formerly the forceps were put on to the head in any man RECENT OBSTETRIC APPLIANCES. 25 ner which wa9 the most, convenient, at the present day their application is in accordance with established rules, each depend- ing upon the position of the head. In 1791, Frederick William Voigtel published a volume, I think the first on the subject, upon the " toucher" and the signs of pregnancy shown by it. In 1S07, the first addition to the obstetric art from America was made by the discovery of the peculiar virtues of Ergot in excit- ing uterine contractions, by Doctor John Stearns, late of this city. The general virtues of this very valuable medicine were for a long period but little known to the mass of practitioners, and its use confined to the younger members of the profession, and those of the elder who have sided in its favor. Many and long were the controversies respecting its virtues. Its value as a medicine in various diseases of women is still under investigation. In 1818, Mr. Mayer, of Geneva, first applied auscultation to the diagnosis of pregnancy—a discovery of very great value to the accoucheur, but a branch to which too little attention is paid by the profession generally. Another operation still, and fully stated in Lecture xxxiv, is the division of the os and cervix uteri in cases of obstinate rigidity, and where the urgency of the case demands the active interfer- ence of the attending physician. When this matter shall be fairly brought to the attention of the profession, I venture to predict that it will take its place as one of the rarely required but possible and justifiable obstetric operations. Of many recent additions to the appliances of obstetric sur- gery I can but merely allude, as their exact value cannot be fully estimated till time has stamped them with its seal; they are, however, more fully mentioned in the following pages. They are the colpeurynter, the sponge tent, the douche, where- with to produce premature delivery ; the uterine sound to diag- nosticate the interior condition and size of the uterus; the measurement of tumors etc.; the speculum used in connection with obstetrics to facilitate the tamponing of the os uteri and the vagina, in cases of haemorrhage ; and in general the improve- ment of the forceps, tractor or vectis, craniotonry forceps, and other instruments, in effect almost equally their recreation, and greatly diminishing the mortality of parturient females. Finally, within the remembrance of all, the application of 2Q ANESTHESIA INTRODUCED. anesthesia to our art has driven away the suffering and the fears from many minds. Early used by Simpson of Edinburgh and .tron-ly recommended by that distinguished physician, it has been received with much distrust in this country. The wife ot Longfellow, our distinguished poet, was the first in America to e-ay its wondrous virtues under the direction of Dr. Bigelow, Senior, of Boston. Its use in that city is now very general, but exceedingly limited in New York, although not a single unfortu- nate case has been reported that I have heard of. Having been myself among the earliest, if not the first, phy- sician in New York to administer chloroform in labor [see cases reported by me, in the voluminous work published in Boston by Dr. Channing, Professor of Obstetrics in Harvard University, entitled " A Treatise on ^Etherization in Child-birth," with reports of 5S1 cases], and having continued ks use until the pre- sent time, I feel entitled, from personal experience, to commend its administration in almost every case of labor, as well in simple and natural as in difficult and instrumental. The religious objections made against its use, that it nullifies the curse " I will greatly multiply thy sorrow and thy concep- tion ; in sorrow thou shalt bring forth children," reminds one of similar discussions respecting craniotomy in olden time, of which the distinguished Astruc thus speaks : 'v Reason itself and daily practice affirm that the mother's (life) should be saved at the expense of the child's; wherefore when authority, reason and example concur in the determination of any affair whatsoever, we should always submit thereto. Yet some divines and phy- sicians of no small note maintain that the infant's life should be rather preserved, that he should not die in original sin, which is washed away by baptism. But as the weight of their arguments is chiefly built on a religious circumstance, the difficulty may be removed in most cases by administering this sacrament to the infant in the mother's womb, whether any part of its body presents itself to our view, or whether it does not, so that the baptismal water may be conveyed immediately on this part by the help of a syringe, breaking its membranes if they intervene ; which practice should be put in execution in all difficult births, before the extraction of the infant is attempted. For it is authorized by able divines and daily example: wherefore rejecting the second, we should acquiesce in the decision of the first pan." OBSTETRIC WRITERS OF THE NINETEENTH CENTURY. 27 The great value of anaesthesia in many cases of operative midwifery, few will pretend to deny, and already a large number of medical men throughout the country approve of its moderate use to mitigate the sufferings of this state. This number I think is greatly increasing, and before this generation has passed away, we will probably see labor rendered painless an every day occurrence. Should it be so, the art of midwifery will have advanced more rapidly in this than in the famous eighteenth century, its golden epoch. The nineteenth century has been prolific in writings. Not to remention Baudelocque and Naegeld, the writings of Moreau, Cazeaux, Chailly (Honore), Colombat, Velpeau, Capuron, Dubois in France; Kiwisch, Bauer and others in Germany; Rigby, Ramsbotham, Gooch, Blundell, Murphy, Churchill, Simpson, Collins, Lee, Hardy,Bennet,Tyler Smith, AVest, Lever, Oldham and many others in Great Britain; Dewees, Bard, Francis, Meigs, Channing, Trask, Oilman in this country, have added much to the reliableness of obstetric knowledge. Add to this the frequent reports of cases and monographs in the numerous journals, the debates in scientific associations, and it may readily be seen that the science is not at a stand-still, but advancing with a rapidity equal to any branch of the healing art. During the dark ages, and probably from the beginning of the world, as I have previously said, the care of women in child- bed appertained exclusively to their own sex. Even Paul of iEgineta, who is styled the first male practitioner of midwifery, in the 7th century, it is probable, had little if any practice. As late as 1552, Dr. Veit, in Hamburg, was publicly branded for having attended as a midwife in female garb. Dr. Atwood was the first physician in New York, who dared advertise himself as a man-midwife before the revolution in 1762. During all this season the most gross empiricism and the most iuperstitious practices reigned in this branch of medicine. The nost simple precepts of hygiene were consecrated by religious ceremonies, which greedy priests, in those days of credulity and ignorance, easily multiplied. Every woman among the Greeks and Romans at the time she first noticed her pregnancy, vent to the temple of Diana and deposited her girdle, and took afterwards garments suitable to her new condition. 28 INEFFICIENCY OF FEMALE OBSTETRICIANS. Although Juno and Lucina presided in a general manner over labor and child-bearing, particular divinities were invoked at every stage, and for every accident in the course of this func- tion. Mena, who appears to be the same as Diana, preserved women from floodings during pregnancy and childbirth. Vows were made to Postversa and Prorsa, when the child presented in an unusual and dangerous manner. During this period we can learn little of the duties of the midwife. This individual seems to have been a remarkable busybody. It is highly probable that she did too much rather than too little. She busied herself about everything which interested women, and was the oracle respecting everything rela- tive to their outward embellishment, the color of the skin, the shape, the breasts, and all sequelae, probably numerous enough, of confinement. She made marriages, procured abortion, and cured sterility ; in short, the Cleopatras, Aspasias and Agno- dices of Ancient Greece, were very similar and probably more ignorant than the infamous Restells and Costellos of our day. At the present time there is a proposition mooted—springing from the same high source which advocates woman's rights, the Bloomer costume, and other similar nonsensical theories—to give again the portion of the healing art of which I am treating, if not the whole domain of medicine, to the females. I have pointed out some of the absurdities of former days, when entirely under the direction of women, and have gradually traced the subse- quent ameliorations, most, if not all of which, have been made since the time of Louis XIV., when Julien Clement, first as an accoucheur, attended Mad'lle Lavalliere, selected by her, as it is reported, because she wished her confinement kept a secret. The student of the history of midwifery will in vain seek to find a single instance recorded of any useful practical discovery made by the midwife. They perpetuated the errors of the time—they have not in a single instance, up to the present day, scarcely excepting Mesdames Lachapelle and Boivin, been the authors of a solitary improvement in the art. In the practice, their success stands in no better light. In 1820 it was stated—and the remark has never been refuted—by the then Professor of Midwifery of the University of New York, Dr. John W. Francis, a gentleman whose deference for the sex is only equalled by the excellence of his judgment and the cer- DUTIES OF CONSCIENTIOUS PHYSICIANS. 29 tainty of his statements, that " the bills of mortality in London and Dublin attest, that one in seventy of those women perish in childbirth who are in the hands of midwives, whilst from the accounts of the lying-in hospitals in those very cities which are under the care of male attendants, parturition is fatal to less than one half the number—nor indeed is the process of parturi- tion so free from difficulties as is by many imagined. We learn, from the last reports under the authority of Mr. Hey, of the Leeds Infirmary, that of 827 cases of Midwifery, one hundred and fifty were such as required manual aid, either with regard to the expulsion of the placenta or child. I hope it is not irre- verent to females to assert, that the acts of resolution and firm- ness which such occurrences impose, are less fitted to their delicacy than to the hardihood of the other sex." It is truly not a matter of wonder that it should be generally supposed that any old woman was capable of taking the charge of a lying-in woman, when it is seen how lightly the subject is treated by the profession itself. Many physicians seem to think, that the only utility to be derived from their presence in the puerperal chamber, is the subsequent fee, and I am inclined to think with them. Their practice is an "expectant" practice in more than one particular. They are willing to allow a woman to remain with the head impacted, or retained by the perinaeum for scores of hours, practising one only of Blundell's excellent instructions, viz., wait. This fatal delay is not the consequence of a settled conviction of the general inadvisability of opera- tions, or in conformity with any opinions in regard to " med- dlesome midwifery^," but solely from an utter ignorance of the true state of things, or from an extreme timidity respecting all interference with nature. It is from these causes that we find so many cases of vesico and recto-vaginal fistulas, which are, I will venture to say, rarely, if ever, the result of an injury from the forceps, as proved by statistics on a future page. While the attendant physician is slumbering in his comfortable rocking- chair, the impacted head is effecting those disorganizations, the responsibility of which he afterwards endeavors to fling off his shoulders, by ascribing this awful result to the forceps. Far be it from me to urge or advocate the frequent use of instruments, but I wish to direct the public attention to the cause of the injurious results which are so willingly ascribed to their use. I think that accurate statistics of the two above men- 30 PROPRIETY OF INSTRUMENTAL INTERFERENCE. tioned injuries, as well as rupture of the uterus during labor, will show that these very much preponderate when forceps have not been used. And allowing; that where instruments were used these sad results occurred in consequence, were they not preferable to the grave ? So much has been said against instrumental interference, that there is little danger, that in this community unnecessary opera- tions will be performed, and so universal is the antipathy to such a resort, that it seems to me that these resources of art are too little called upon, and thereby much unnecessary suffering per- mitted, and much injury done to the women, and children's lives unnecessarily sacrificed. I have been sometimes inclined to think, when seeing the lit- tle efforts made to resuscitate the still-born babe in the Parisian hospitals, that they thought a life which, for a long series of years afterwards, was to be at the expense of the state, was scarcely worth the trouble of saving; and it sometimes seems as if physicians here thought it perhaps better humanity, to allow children to perish impacted in the pelvis, or from the effects of ergot wrongly administered, rather than to deliver them by instruments, and allow them to live a life afterwards to be exposed to hunger, cold and filth, finally to be swept away by the yearly recurring cholera infantum or the wasting mar- asmus. The aim of the physician is clearly stated by Ramsbotham, to strive, " equally to escape the imputation of haste and indiscre- tion on the one hand, and of delay and indecision on the other; yet let us ever bear in mind, that more injury may possibly accrue from too long delay than arise from premature assis- tance." In similar terms speak the great mass of the teachers of the world. The great want of the profession in this particular, is knowledge of the subject. What if the finger can pass freely around the sides of the head, and the pelvis seems sufficiently spacious ? if the long diameter of the head of the foetus is present- ing to the short diameter of the pelvis, human interference is demanded. The diagnosis therefore of the position is equally important as that of the presentation. The next want of the profession is decision, and here I may again quote from the celebrated preface of the American edition of Denman's Introduction to Midwifery. "Nowhere are promp- DANGERS THREATENING THE PROFESSION. 31 titude and decision more required; in no situation is the man of science more distinguishable from the mere pretender; in no situation is the conduct of the physician more the object of pre- sent attention or of subsequent criticism. In the lying-in cham- ber no opportunity is afforded for qualification or deliberation. The case demands immediate assistance, and it is vain to tem- porize ; vacillation and delay, always dangerous, may here prove fatal. The student's mind must be thoroughly prepared, else the imputation of ignorance will attend his hesitation and confusion. Firmness and decision, founded on accurate and precise know- ledge, will alone secure to him present confidence and future approbation." Two dangers now menace the practice of midwifery in this country, either of which threatens to do it an irreparable injury. The one which particular!}' concerns us is the carelessness and inefficiency of the profession itself. The students at graduation know little or nothing of the subject. Practically, they are entirely ignorant of its simplest forms. They have no methodized habits, no illustrative reminiscences to throw light upon the obscurities which may occur in their subsequent practice. The student may graduate without ever having attended at the bed- side of a parturient woman. After the first few cases, in which he is sufficiently alarmed, but which, fortunately, pass by suc- cessfully, he concludes that all the talk of position, presentation, rotation, and such like terms, is all nonsense, or at the best, theoretical, and he joins the "expectant" practitioners, trusts to the vis medicatrix naturae, confidently expects that spontane- ous evolution will always occur, and by a dull inactivity, result- ing from ignorance, loses the child, and not unfrequently the mother also, and injures the reputation of the profession, the capabilities and attainments of which he does not understand. The next great danger springs from the love of mammon. Ignorance and presumption, which thrive upon ignorance and credulity, when " fools rush in where angels fear to tread." The dark ages seem to be again reviving. Hand in hand with the infinitesimals and the water wonder-worker, comes the hard-faced midwife, tinctured with both theories (for theory means absurdity now, and professor is a term applied to moun- tebanks and quacks). We have lecturers and lecturesses, and female colleges, where the very large and highly intelligent 32 QUACKERY IN OBSTETRICS. classes are taught how to get children, and especially how not to get them. The Woman's Rights Convention cannot see why women should bear children more than men, and while waiting- some plan to equalize this matter, they refuse to bear them them- selves. From these fields of literature come the midwives, with reck- less rashness, not like our Californian adventurers, themselves to incur any perils for the sake of gold, but to allow the unfortu- nates who confide in them to run any risk, and to suffer any calamity which their temerity and ignorance might cause. Wet sheets and globules are poor substitutes for science and practical skill. Quackery, gentlemen, is rife in every branch of the profes- sion, and revolutionary opinions are being expressed in various of its domains—the province of midwifery threatens to secede from the union by which she is bound to medicine and surgery. Shall we allow such an act to be accomplished, to the manifest detriment of all parties concerned ? Against such a result we must arm ourselves by fresh acquisitions ; we must rub off the rust from our old learning, and by constant study and watchful- ness be ever ready to maintain the dignity, integrity and efficiency of the healing art. What the future may be, depends upon us. The present is ours, the past is ours also; for medicine is not a science of yesterday, nor the dream of any wild schemer, but one originating in antiquity, practised by the Redeemer, handed down, enriched and improved, through centuries, to be perfected only in eternity. The greatest minds of the earth have given the admiration of their youth, their manhood has improved, ornamented and simplified, and their old age has relied upon it. The vegetable and mineral kingdoms are closely allied, and kin- dred sciences give to it their strong support. This is the lofty fabric planned by the Great Architect, founded upon a rock of adamant, which has resisted the storms of time, the floods of per- secution and ridicule, the stormy gusts of passion and envy, and remains not only unscathed, but whose fair proportions are daily more colossal and finished. This is the glorious edifice that you would tear down, to build upon its ruins a flimsy structure of ephemeral materials and shapeless construction, " the baseless fabric of a vision, to melt away, leaving not a rack behind." W. TYLER SMITH ON THE THEORY ^lISTD PRACTICE OF OBSTETRICS. ---------<»» LECTURE I. GENERATION. Gentlemen :—In this, the first Lecture of a Course on the Theory and Practice of Obstetrics, it is proposed to draw atten* tion to some general considerations concerning the reproduction and development of living beings. Beginning with matters re- lating to the most simple modes by which the propagation of animals can be effected, we may ascend to the study of the higher forms of reproduction, until we arrive at the generation of the human species. It will be found, as we proceed, that there are no races so low in the scale of creation but that tho history of their generative phenomena is calculated to throw light upon the same functions in classes of the highest rank .in the animal kingdom. This circumstance must plead as my excuse for attempting to deal, at the commencement, with the elements or principles of generation. At the very threshold of this subject, we are met by the long- agitated question of Spontaneous or Equivocal Generation. Can any form of animal life be produced upon the globe we inhabit, out of dead inanimate matter, or indeed otherwise than 3 ** 34 SPONTANEOUS GENERATION- —INFUSORIA. as part of a procession or series of living organisms, every genera- tion of which must depend for its existence upon the generations that have preceded it ? In former times, many facts connected with the generation of the humbler forms of living matter seemed altogether inexplicable; and naturalists and physiologists were driven to a belief in the doctrine that, under special cir- cumstances, such as the decomposition of animal and vegetable structures, some of the lower forms of animal existence might be developed spontaneously. The progress of knowledge has, however, steadily diminished the number of these mysteries: and it may be said that, in recent days, the last stronghold of the believers in spontaneous generation has been the condi- tions under which the Infusoria and Entozoa can be produced. From any vegetable infusion, under certain regulations as regards light, air, and temperature, myriads of microscopical infusoria are called into existence. The same infusions uni- formly produce the same animalcules, and the lowest forms of infusorial life are those which first appear. The results are the same when water, which has been boiled or distilled, is used ; and observers of eminence have declared that they have seen the debris of vegetable matter, while undergoing decomposition, transformed into infusoria. Others have believed that animal- cules may be produced, by the action of electricity, from silica •and similar inorganic matters. It may, however, be said, at the present time, with regard to infusoria, that the difficulties in the way of explaining their almost omnipresence have disap- peared, and that their production, except under natural circum- stances, can be satisfactorily disproved. The different modes of propagation in the infusoria have been investigated, and it is known that in their most simple form, the perfect infusoria, and in other cases the germs, are almost innu- merable, and of well-nigh unextinguishable vitality. One animalcule, the Monas crepusculus, is 2~o of a line in diameter; and it is remarked by Professor Owen that a single drop of water may contain no less than five hundred millions of these minute beings. The drop evaporated, this vast population, greater in number than the living inhabitants of the world, be- come dry and preserve their latent life in the air and in the dust of the earth, to be revivified on the occurrence of the conditions necessary to their existence. Not a mote of the sunbeam but is ANIMALCULES. 35 peopled with these animalcular organisms. Their power of resisting destructive agencies is not one of their least wonderful properties. They live in water under ice, or inclosed in vesicles in the ice itself. Fontana revived some specimens of Rotifera after they had been exposed to the sun for upwards of two years in dry sand; and Spallanzani and Schultze have revived them after four years of desiccation. Other animalcules, in drying, burst, and liberate myriads of germs, which preserve their vitality under almost' every conceiveable circumstance. These and similar facts show that no particle of air, dust or wa- ter can be taken which does not contain infusoria or their germs, thus rendering it almost certain that the vegetable infusion does nothing more than favor the restoration of dried ani- malcules, or the development of their invisible germs. But the cxperimentum crucis respecting the spontaneous generation of the infusoria has been applied by Schwann and Schultze. The access of air, which no doubt contains infusoria or their germs, is known to be necessary to the production of animal- cules in vegetable infusions. One of these experimenters passed the air employed through caustic potash and through strong sul- phuric acid ; and the other through iron tubes heated to redness, the infusions used having been previously boiled. Under these conditions no infusoria were produced, though a rapid develop- ment of animalcules occurred on the admission of air to simi- lar infusions, when no such precautions were observed. As regards the Entozoa, the presumptive evidence in favor of their spontaneous generation was still more conclusive than in the case of the infusoria. Entozoa are found in situations to which they could not be supposed to have access by any natural means. The Cysticercus celhdosoe is found in the anterior cham- ber of the eye, in the choroid plexus, and in the substance of the heart. The Trichina spiralis infests the voluntary muscles, and the Strongylus gig as the parenchyma of the kidney. A di- plostomum in the aqueous humor has itself been found to be infested with parasitic animalcules. Entozoa have been detected in the foetus in utero, in the blood, and in the eggs of oviparous animals. Such facts appear to present insuperable difficulties to the explanation of the existence of entozoa in their special habitats, unless upon the supposition that.they are produced spontaneously. It came to be known that many of the higher 36 ENTOZOA. forms of entozoa possess complicated organs of generation, and produced ova and embryos in abundance, which themselves be- came the subject of observation. For a time, however, this knowledge only increased the difficulty. How could entozoa reach the foetus, or enter the eye, when their ova were known to greatly exceed the diameter of the capillary vessels ? It was at last discovered, that the entozoa, particularly in their embryo forms, possess a special boring apparatus, which had been noticed by John Hunter in some species, by means of which they are able to make their way through the solid tissues of the body with extraordinary facility, producing little or no disturbance in their progress, and leaving no traces of their ope- rations behind them. It was also found that a vast variety of special provisions existed for the diffusion and localization of these creatures. The numbers, too, of the ova of some of the entozoa are immense. A single specimen of the Tcenia serrate, an entozoon which infests the dog, will produce twenty-five millions of ova! while a mature female of the Ascaris lumbri- coidcs will contain upwards of sixty millions ! Many of them pass through several phases of existence in different animals before they arrive at the perfect state, provision being made for their transfer from one animal to another. It is believed that in every species of tape worm, two animals, are at least necessary for their complete development, and of these two ani- mals, the one generally stands in the relation of food, or prey to the other. Thus the scolex, er embryo head, of the Tcenia crassicolis, is found in the mouse, while the perfect taenia infests the intestines of the cat. The mouse is of course the means of introducing the embryo of the taenia into the larger animal. The power of the entozoa in resisting destructive agents is even greater than the infusoria. Some of these worms of complicated structure remain alive after being boiled a considerable time; others are reanimated after being frozen for several weeks. Their ova have still greater powers of self-preservation. These and similar facts respecting their numbers, modes of generation, indes- tructibility, and powers of penetrating animal tissues, appear suffi- cient to explain all the seeming mysteries respecting the entozoa without resorting to the theory of spontaneous generation. The most simple form of animal life is that met with in the Gregarinae, a genus of microscopic entozoa found in the inter- SIMPLEST TYPE OF REPRODUCTION. 37 ruL l nal organs of worms and insects. The Gregarina consists essen- tially of a single cell, or of a cell-wall with its contained-fluid, and a central nucleus. (Fig. 1.) It moves by contraction of its cell-wall, and only differs from a vegetable cell in its contractility, and its solubility in acetic acid. In the simplest infusoria, the polygastrian ani- malcules, a class below the entozoa in the animal series, the same monadiform organization is found; and throughout the infusoria, although many addi- tions, in the shape of cilia, and internal organs oc- cur, the type of a cell, with a central nucleus, or nuclei, is preserved. This central portion consists of hyaline matter, of an amber colour, which is sup- posed to be fatty in character, and is believed to bear a resemblance to the spermatic particles of higher animals. The Chlamydomonas may be cited as one of the simplest of the infusoria. (Fig. 2.) The primary and most simple type of reproduc- tion, that which is found in these unicellular, mo- nadiform animalcules, is that of spontaneous fission, or Fissiparous Generation, as it is called. In this mode of reproduction, in the most simple forms of infusoria, a single unicellular animalcule divides into two or more cells, which, after their division, become similar to the parent cell. The first infusorial animal- cule ever known, the Vorticella convallaria, discovered by Leeuwenhoeck nearly two hundred years ago, multiplies itself in this manner. Sometimes the fissure takes place longitudi- nally, at others transversely (Fig 3,) a notch first appearing at Gregarina. Jfto.2. Fig. 3. A, B, C. Longitudinal fissure of elongated infusoria. D, E, P. Transverse fission of oval ani- malcules. the point of subsequent division, which enlarges until the separation is nearly completed, when the two cells struggle, by 38 FISSIPAROUS GENERATION. means of their cilia, until they are free from each other, and swim off as independent animalcules. In some infusoria the fission consists in a simple division of one cell into two. In others, they divide, but still remain connected in groups, as a chain or in a spherical mass. The latter is the case with the Volvox globator, a well known animalcule. Instances are met with in which the division of succeeding generations are regular multiples of each other, as two, four, eight, and so on. This occurs for instance, in the Chlamydomonas. (Fig. 4.) In the Fig. 4. A, B, C. Multiple fission of Chlamydomonas. n, Nuclei. process of fission, the nucleus is always the first part to divide, and it is this cleavage of the nuclear portion which rules the segmentation of the whole cell. In these simple organisms, the sperm and germ-force reside in the nucleus or nuclear par- ticles—every nucleated infusorial cell, multiplying in this way, being from its birth, as it were, impregnated and ready to pro- pagate its kind by fission. No diminution of the reproductive force is caused by successive fissions, each generation of purely fissiparous animalcules having the same powers as its progeni- tors. Many infusoria multiply by other modes of generation as well as by fission, but the rate of increase by this means alone is very great. The Paramcecium aurelia, if well fed, divides every twenty-four hours, its progeny in successive generations continuing to divide in the same ratio. In this way, in the course of four weeks, one animalcule will produce upwards of two hundred and fifty millions of new beings. This fissiparous mode of generation is found not only in Infusoria and Entozoa, but in Polypi, Medusae, and Annulata. It is in the Infusoria also that the first acts of parturition are observed. In the Lox- odes Bursaria, four or five cells are formed in the interior of the animalcule, which are gradually developed into embryos. These embryos make their way slowly through the tissues of the parent and escape externally. No aperture or channel exists GEMMIPAROUS GENERATION. 39 previously, and the situation of the parturient escape of the em- bryo seems entirely to depend upon accident. (Fig. 5.) At whatever part of the parent organism the embryo is developed Fig. 6. A, B. Formation of germs and embryos in Loxodes Bursaria. C. The process of parturition. D, E. Free moving embryos. there a way is made for its escape. Sometimes two or three embryos are escaping from different parts of the parent at the same time. From this simple beginning, the extrusion of the ova and embryo goes on in the animal series, until it reaches the complexity and difficulty witnessed in the higher mam- malia and in the human species. The next form of reproduction met with in the animal kingdom is Gemmiparous Generation, in which the offspring arise from the parent in the shape of gemmae, or buds, which acquire a similar organization of the parent animal, and separate to as- sume an independent existence. In the Hydra viridis for in- stance, a prominence first appears upon the surface of the ani- mal, which gradually assumes the form of a miniature polyp. It contains a cavity, which, in the first instance, communicates with the stomach of the parent Hydra. An oval aperture, sur- rounded with tentacles, is developed at its free extremity. At 40 REPRODUCTION OF POLYPS. first the food digested in the stomachal cavity of the parent sup- plies the gemmule, but, after a time, the young polyp begins to catch food, and contributes to the support of itself and parent. At length its connection with the parent polyp becomes slender, and it separates altogether. (Fig. 6.) Another mode of gem- Fig. 6. o A, B, C. Polypoid Acalephs, giving off gemmas or buds. miparous generation is where, as in the sponges, small free gemmules, or buds, are separated from the body of the parent animal, and become developed into perfect individuals. The part of the body from which gemmation takes place indifferent animals is very various. In some, it may occur at any part of the surface of the body ; in others the gemmules are formed in the digestive cavity, and extruded from the oval aperture. In the medusae, the gemmae arise from the ovaries, stomach, pro- boscis, and tentacles. In other other cases, as in the Alcyoni- dium elegans, an Alcyonian zoophyte, the tubercles which con- stitute the gemmae, or buds, are produced in particular strips of tegumentary membrane. In some of the gemmiparous animals, new creatures may be multiplied to almost any extent by mechanical division. The Hydra viridis may be divided lon- gitudinally or transversely into several parts, and each fragment will become a perfect polyp ; or if a wound is made in the body of the animal, a new polyp sprouts from the site of injury. The gemmiparous form of generation is met with in a large variety of animals. It exists in the Infusoria, Entozoa, Polypi, Medusae Annulata, and Tunicata. In the Nereis, and in some of themy- riapoda, gemmation forms an important part of the reproduc- tive process. In the former, a constriction first appears in the tail of the animal, immediately behind which the head of a new nereis is developed, and the posterior division becomes separ- ated from the anterior, or parent nereis, as a perfect animal. CONJUGATE GENERATION. 41 The earliest traces of a dioecious mode of reproduction in ani- mals, in which two individuals are engaged in the production of offspring, is met with in the humble Gregarina already men- tioned. These microscopical entozoa propagate not only by fis- sion, but by a process termed conjugation. In the latter mode of generation, two of the elongated cells or animalcules are said by Stein and other observers to approach each other; the two ends which are in opposition become flattened, so that the two conjoined animalcules resemble a single Gregarina in shape. A complete fusion of the granular contents of the two individuals takes place, and from the joint mass a number of small bodies are produced, which are believed to be the embryos of this monadiform entozoon. (Fig. 7.) Other instances of Conju- Fig. 7. Conjugation of Gregarinae. A. single Gregarina. B, C, D. Two animalcules in a state of conjuga- tion. E, F, G. Formation of embryos. H. Free embryos. gate Generation have been observed by Kolliker, Siebold, and Cohn. This mode of generation appears to be quite wanting in anything of an ordinary sexual character. The conjugating Gregarinae appear to be precisely similar to each other, and their reproduction seems to be by a kind of duplicate fission. It is, however, impossible not to be struck with the similarity of the process of conjugation, and the union of the sperm cell and germ cell in the higher animals, to which sex has been added in the scheme of reproduction. In the latter case, the sperm and 42 HERMAPHRODITE GENERATION. germ cells unite to produce, by division and subdivision, the particles forming the germ mass, and out of which the embryo is evolved. As soon as sexual generation commences, two kinds of cells are required in the process of reproduction—one produced in the ovarium, the other in the testes. In the lower classes these two organs are frequently found upon the same in- dividual, constituting complete hermaphrodite generation. In other instances the individuals are hermaphrodite, but the mu- tual congress of two or more animals is necessary for fertiliza- tion. In the higher classes, hermaphrodism disappears, and the ovarium and testes, with the sperm and germ cell, belong to different animals and sexes. The present seems to be the proper place for making some general remarks on the subjects of Fissiparous and Gemmiparous generation, and the relation of these processes to the acts of re- production in the higher animals. The principle of fission is not limited to animals in which it constitutes the chief mode of gen- eration. It extends in a certain degree to the higher forms of animal reproduction. In oviparous animals and mammalia it may be said that the dehiscence of the ovule or of the im- pregnated ovum, from the ovarium, is a kind of fission. A still closer analogy to the phenomena of fission is found in the early changes in the interior of the mammalian ovum after impregnation and indeed of the ovum of all animals multiplying by sexual generation. (Fig. 8.) These changes are similar to those Fig. 8. Development of Ascaris acuminata by repeated fission of the germ celL Type of development in all animals produced from ova. which have been referred to as occurring in the unicellular infu- soria. That which will hereafter have to be described as the sez- SEXUAL GENERATION. 43 mentation or cleavage of the yelk, consists in the division and subdivision of the embryo cell, and is almost identical with the multiple fission of the Chlamydomonas an analogy first pointed out by the late Dr. Martin Barry. The only difference is, that in the Chlamydomonas and Gregarina the divisions and subdi- visions produce independent and perfect animals ; whereas in the mammalian ovum the fission results in a mass of germ cells, intended to pass on to higher developments. In animals, the sub- jects of sexual generation, the male element is also formed by the rupture of the primary germ cells secreted by the testes, and the conversion of their nuclear matter into spermatozoa, which may in fact be considered as secondary germ cells. It may also be said that the human fabric is the result of the fis- sion, an innumerable number of times repeated, of the single fertilized embryo cell; the multitudes of cells produced by the rupture and fission of generation after generation of cells, and by the conversion of. their nuclei in turn into parent cells, being converted by plastic morphological forces, into bone, mus- cle, nerve, blood, and the other elements of which the body is composed. The similarity of the ciliated epithelial cell of the mucous membranes to the ciliated unicellular infusoria is very palpable. It is of myriads of such cells, modified in infinite ways, that the human organism is constructed. In this way we can to a certain extent realize the idea of Buffon, when he said that all animal and vegetable bodies were aggregations of ani- malcules ; or the more positive remark of Oken, that the higher animals and man himself, were agglomerations of infusoria. Generation byr means of buds or gemmae is still more exten- sive than reproduction by fission. In gemmiparous animals, re- productive nuclei are scattered throughout the structures and tissues of the parent organisms; it is a fission occurring, not, as it were, in the whole animal, but in particular parts. The mode of reproduction by generation extends higher than fissiparous generation, being found, as we have said, as high as the Tunicata, and it is concerned in Alternate Generation, which is found amongst insects. But the principle is not lost at the point when it ceases to be a mode of generation. It is concerned in the re- production of lost parts. In gemmiparous generation, animals are formed, not from ova, or from the fission of primary repro- ductive cells, but from secondary or derivative germ cells, 44 VIRGIN PROCREATION. placed in reserve in the tissues of animals. In the triton or the lobster, in which the tail or claw is reproduced, the new forma- tion occurs from derivative germ cells placed in the tail or claw —that is, a reserve of derivative germ cells, not used in the general development, is deposited in different parts of the body. In mammalia, the extremities of the foetus are always formed by budding or gemmation. It is believed by some observers that in the human foetus, if a limb be amputated spontaneously in utero, at an early period, there is an attempt at the production of a new limb by germination. In some of the remarkable cases of spontaneous amputation of limbs in utero, first investigated by Dr. Montgomery and Professor Simpson, the amputated limb is found in the uterus, and from the stump small or rudi- mentary fingers or toes are seen to be growing, which remain visible in after life. One of the most remarkable phenomena in the history of generation is that first investigated by Bonnet, Reaumur, Steen- strup, and others, and to which great significance has been given by Professor Owen, under the name of Parthogenesis, or Tirgin Procreation. In many forms of animal life—as, for instance, in the Salpae amongst mollusca, the Distomata amongst entozoa, and the Aphides amongst insects—it is found that the parent animal gives birth to an embryo different to itself; that this em- bryo lives as an independent animal, but gives birth, without sexual intercourse, to another, and to a successive series, until at length a progeny is formed bearing the likeness of the original parent. In the Distoma, the embryos have at first the form of ciliated monads, and these are metamorphosed into Gregariniform worms. In the interior of each of the latter, numbers of Cer- cariform, or tailed animalcules, are developed, which in turn be- come true Distomata. In the winged Aphis, the ova are depos- ited by the parent insect, and in due time produce larval, wind- less aphides. Each virgin aphis of this brood will produce other similar broods without contact with the male. This Lu- cina sine concubitu has been observed to go on to the eleventh generation, the last generation being winged, and male and female. These have intercourse, another fecundation occurs, and in the following summer the phenomena which have been described again occur. OVIPAROUS, GENERATION. 45 The explanation of these cases is, that in the first instance the coitus fertilizes the ovum, and part of the derivative germ cells produced from the embryo cell, instead of being consumed in the development of the first generation of aphides, are kept as a reserve. In the second generation, these derivative germ cells give origin to a new generation of derivative germinal cells, of which a reserve remains as before, and so on until the spermatic force of the germ cell is exhausted. To illustrate this matter, let us look to the early development of the mammalian ovum. The embryo cell divides into two, these two into four, the four into eight, and it is not until the segmentation has affected the whole mass of the germ and yelk that the formation of the new individual begins. But suppose each generation of germ cells occurring in this fission or segmentation, to have the power of going on to the production of new individuals, we should then have the power observed in the virgin aphides, where each gen- eration of germ cells goes on to the production of a larval aphis before a new fission or segmentation of the derivative germ cells takes place. We may see traces of this power of the sperma- tic element to fertilize or modify more than one generation of ova and germ cells in other animals than those in which perfect parthogenesis occurs. For instance, a single coitus of the cock fertilizes, not only the eggs which are mature in the ovary, but those which are immature, so that eggs which reach maturity a long time after coitus are found to be fertilized. The patho- genetic influence may even be seen in the mammalia and in the human female. In the well-known case of the mare covered by the Quagga, the foals produced afterwards, by intercourse with her own kind, still bore the stripes of the quagga. In the human^female, it is found, that a woman having married and borne children by her husband, becomes a widow, marries a second time, and bears children to her second husband which have the lineaments of her first husband. The same occurs in the lower animals, and it is difficult to explain the matter in any other way than by supposing that one coitus must have influ- enced several generations of ova. The relation of such pheno- mena to parthogenesis is obvious. The next step in the process of reproduction brings us to Oviparous Generation. This form of generation is very early met with in the animal series. Ehrenberg discovered in many of the Rotiferous animalcules distinct male and female organs, 46 METHODS OF IMPREGNATION. and generation by means of fecundated ova. In some of the more simple infusoria, ova appear to be formed in the general parenchyma of the body without any sexual operation, and to be extruded in the form of a reticulated mass. In the lower part of the zoological scale, oviparous generation is mixed up with fissiparous and gemmiparous generation, and there seems to be hardly any difference between the production of free gemmules to be developed apart from the parent, and the formation and elimination of ova from the infusoria, in whom distinct sex is wanting. It is in Insects, Fishes, Reptiles, and Birds, that ovi- parous generation reaches its full development. In insects, the ova, which consist of a germinal vesicle, yelk, albuminous and shelly coverings, are very small, and the embryyo is early extruded from the shell in a larval state, but fitted to acquire its own nourishment, and passing through numerous metamorphoses before it reaches the perfect condition. All insects are dioecious, or of distinct sex, and the impregnation of the ova occurs within the body of the female. In fishes the sexes are also distinct, and in this class we get the first commencement of the ovarium as it exists in the higher vertebrata and mammalia. In the lower types of fishes the ovarium consists of a mere vascular lamina, in which the ova are formed and thrown off into the abdominal cavity, from which they escape by orifices near the anal aper- ture. In the higher specimens of this class an oviduct is added for the purpose of conveying the ova from the ovarium. The ova of fishes are generally impregnated out of the body, but in some cases impregnation and development to a certain extent occur within the ovary, the male having a rudimentary intromit- tent organ, and the embryo is expelled in a living state. In reptiles the oviduct is a permanent condition; the ova *are gen- erally fecundated out of the body, in transitu, by the lower gen- era ; but in the more advanced specimens of this class ova are impregnated within the body of the female, and in some of them the young are born alive. In birds, the ova are contained in ovaries, and the egg reaches its highest state of development, consisting of the germinal vesicle and a large yelk; an extensive layer of albumen or white being also added so as to support the development of the young, with various membranes for the protection of the egg, and the maturation of the ovum. Paren- tal affection, of which there are traces in insects and fishes, is present to a very great degree in the case of the bird. MARSUPIAL REPRODUCTION. 47 In the mammalia we have, in all cases, viviparous generation, though some are termed ovoviviparous, but the instances of ovoviviparous generation in birds, amphibia, and fishes, in which the eggs are hatched in the body of the parents, are very dif- ferent from any of the forms of generation met with in the mammalia. In the monotrematous type there is a near approach to the bird ; and as the phenomena of generation have not been actually observed, it is only by analogical reasoning that Profes- sor Owen has arrived at the conclusion that the Ornithorhyn- chus brings forth its young alive. In marsupial reproduction, the impregnated ovum remains a short time in the uterus, and receives nourishment, but at a very early period of development it is transferred from the uterus to the marsupium or pouch, where it hangs by the nipple during the rest of its foetal development. Neither in the monotremata nor the marsupiata has any vascular connection between the parents and the ovum been observed. The uterus enlarges; and it is probably by a secretion found within its cavity, and absorbed by the yelk, that the young embryo is developed. In the higher mammalia, a true vascular connection is formed between the ovum and the mother by means of the chorion and the mucous membrane of the uterus; and the embryo, after a prolonged term of intra-uterine development, is expelled to pass through another protracted phase of maternal nutrition from the mammae. In mammalia, except in the lowest types, we have the separation of the generative canal from the urinary and intestinal organs. The generative organs reach their greatest state of development in the human species, and consist of parts adapted to coitus, ovulation, menstruation, impregnation, utero- gestation', parturition, and lactation—functions which are placed in relation to the highest affection and parental love. The vas- cular intra-uterine connection between the mother and foetus acquires its most perfect development in the placenta of the human species, and it is mainly owing to this intimate vascular relation, the intricacy of the organs of generation, the arrange- ments of the pelvis in accordance with the upright position, and the development of the human intellect, as evidenced by the comparatively large size of the brain and cranium of the human foetus, that the pains and perils of childbirth, and the necessity for the cultivation and practice of Obstetrics, are produced. LECTURE II. the external organs of generation. Gentlemen :—The Organs of Generation in the female are generally divided into the external, or those chiefly concerned in coitus, and the internal, or those employed in the development of the ovum. To the former belong the mons veneris, the labia majora and minora, the clitoris, the hymen or carunculae myrtiformes, the perinaeum, the vagina and the mammae; the latter includes the uterus and its ligaments, the Fallopian tubes, and the ovaria. Both the internal and external organs have important relations to utero-gestation and parturition. The Mons Veneris is a cushion-like layer of adipose and cel- lular tisssue, developed at the time of puberty, situated in front of, and above, the pubes. It is covered by a thick integument studded with hair. Its use is to guard the pubes from mecha- nical violence during intercourse, and to act like the hair of the axilla in defending this part of the body from the effects of fric- tion and perspiration. In general, the hair of the mons is short and curled ; but, in sterile women, I have sometimes observed it to be straight, and longer or shorter than usual—this condition being indicative of a feeble development of the internal organs of generation. The Iiabia Majora, or labia pudendi, are two folds extending downwards on each side from the mons veneris to the perinaeum. They are thick, and lie in contact, above; but below they become thinner, and are separated from each other. Externally, the labia majora are covered by skin, which has a smaller quan- tity of hair upon it than the mons; but internally, they are lined with the commencement of the genito-urinary mucous membrane, and are studded with numerous sebaceous follicles, which secrete a fatty and odorous matter. The union of the labia above constitutes the superior commissure; and that below, 48 external organs of generation. 49 the inferior commissure of the pudenda. Within the posterior com- missure, a fold of mucous membrane stretches across between the labia, which has been called the fourchette, though the same name is frequently applied to the commissure itself at the com- mencement of the perinaeum. The fold, or frenulum referred to, is almost always lacerated in first labors; but before this laceration has taken place, and particularly during labor, a dis- tinct depression, or fossa, can be felt between the frenulum and the edge of the perinaeum, termed the fossa navicularis. (Fig. 9.) About an inch beneath the anterior commissure and between the labia majora, is found the Clitoris, which resembles a small penis, and is, in fact, the analogue of the penis of the male. It is composed of two corpora cavernosa, which are attached by crura to the rami of the ischium and pubes, and meet together in the median line. Each of these bodies is enveloped in a thin, fibrous sheath. The clitoris is imperforate, but at its point there is a small spongy or cavernous mass, called the glans, and covered by a fold of integument, or imperfect prepuce. It has two muscles—the erectores clitoridis, representing the erectores penis, arising from the rami of the pubes and ischium, as low down as the tuberosities, and inserted into the crura clitoridis. A suspensory ligament connects the clitoris with the pubes. It is supplied with blood by the internal pudic artery, and pos- sesses a dorsal vein, similar to the vena dorsalis penis. The clitoris is capable of erection, and when in the erectile state is almost of cartilaginous hardness. It is the chief seat of sexual sensibility, constituting, according to Dr. Meigs, " the organ of touch to the aphrodisiac sense." In hysterical females, it is sometimes subject to a constant erection, almost similar to that observed in priapism in the male. During this condition, it is difficult or impossible to pass urine—apoint first noticed, I believe, by Dr. Silvester, of Clapham. These are, in fact, the cases in which, in hysterical subjects, the catheter is often employed. I have observed the clitoris to be subject to a peculiar mechani- cal displacement, or dislocation, in females who have been the subjects of self-abuse. It becomes loose, probably from relax- ation of the suspensory ligament, and is raised higher over the pubes than is natural. When such women marry, they are often deficient in the sexual orgasm during coitus, in consequence of the removal of the clitoris from its proper position. The clitoris 4 50 CLITORIS, NYMrHAE, VESTIBULE. is larger, comparatively, and more prominent, in the infant than the adult. It is subject to hypertrophy, but the special sense is not increased in such cases, in proportion to the hypertrophic growth. The clitoris receives large branches from the internal pudic nerves; and in some of the lower animals, Pacinian bodies have been found in this organ. The Labia Minora, or nymphae, are two folds of mucous membrane extending from the prepuce of the clitoris, downwards and outwards, for about an inch and a half or two inches. Externally, there is a furrow betwixt these folds and the labia majora, covered with the commencing mucous membrane, and studded with numerous fat-glands ; and, internally, they form the commencement of the vagina. On their inner surface may be seen the openings of numerous mucous follicles, from which mucus is secreted for the lubrication of the ostium vaginae. The separated nymphae have been compared to the fissured male urethra from arrest of development in hypospadia, and the analogues of the bulb and corpora spongiosa are found deeply seated behind the nymphae. These consist of a plexus of veins lying on each side of the clitoris, called the pars intermedia; and of two leech-shaped masses of reticulated veins inclosed in a fibrous sheath. The bulbous masses were known to the older anatomists, De Graaf and Santorini, but they have been described anew by Mr. Guthrie, Kobelt, and others. The bulbs are situated below the pars intermedia, and behind the middle and lower portions of the nymphae. They have received various names, such as plexus retiformes, bulbi vestibuli, and crura cli- toridis interna. The objects both of the labia majora and minora are, no doubt, to defend the genital fissure, to afford an extensive sexual surface, and to facilitate the expansion and dilatation of the pudenda during parturition. Below the clitoris and between the nymphae there is a grooved space, about an inch long, pointed above and broader below, termed the Vestibule. In the centre, and at the lower portion of the vestibule, is situated the Meatus Urinarius, consisting of a raised and irregular rim of mucous membrane, with an open- ing in the middle. The eminence is caused by a slight pucker- ing of the mucous membrane by the contractile fibres which keep the meatus closed under ordinary circumstances, an arrangement which admits of considerable distension during mic- METHODS OF CATHETERISM. 51 turition, or in catheterism. The meatus is generally so promi- nent as to be readily felt by the experienced finger. (Fig. 9.) Fig. 9. 1, Vena Dorsalis; 2, Glans Clitoridis ; 8, Crus Clitoridis; 4, Meatus Urinarius; 5, Bulbus Vestibuli 6, Vulvo-vaginal Gland ; 7, Sphincter Vaginae. Catheterism of the female bladder is one of the minor opera- tions at which the accoucheur ought to be expert, and in this place a few remarks may be made on the mode of finding the urethra, and passing the catheter. We have to draw off the urine in the unimpregnated state, during pregnancy and labor, or after delivery, and under other circumstances in which the meatus and urethra may be considerably displaced. The situa- tion of the meatus has already been indicated, and the length of the urethra is about an inch and a quarter. The meatus itself is on a level with the summit of the pubic arch, the bladder being in the natural condition above the pubes, and the direction of the urethra is backwards and upwards, or the same as the lower part of the anterior wall of the vagina, in which it is embedded. The urethra may be felt rolling like a cord under the finger between the vaginal wall and the symphysis pubis. There are two or three modes of finding the urethra in catheter- ism, without exposing the patient—a matter which, of course, should always be avoided, if possible. The woman may be placed on her back or on the left side, and the attendant having found the anterior commissure, with the index finger of his left hand, should pass the finger down lightly over the clitoris to the 52 DIFFICULTIES OF CATHETERISM. bottom of the vestibule, when he may feel the borders of the raised meatus, and, with a cultivated sense of touch, the aper- ture in its centre may be made out. The catheter should be passed over the point of the finger, which may be used both as a director, and to steady the parts into the canal, when it gene- rally passes readily into the bladder, the handle of the instru- ment being a little depressed while it is passing. It must be remembered that the meatus is an aperture in a mucous surface, and it may be searched for with the point of the catheter, if the canal is not readily found. Occasionally, however, the meatus is in a state of firm contraction, and must be hit exactly in order to pass the catheter. This spasmodic contraction of the meatus, and of the whole canal, is met with in hysterical sub- jects. In another and better mode of performing the operation, the accoucheur first finds the cord-like urethra in the upper wall of the vagina, and withdrawing it, feels for the meatus with the index finger of one hand, at the angle formed by the lower part of the vagina and the vestibule, and introduces the instrument with the other. In a third mode, the operator knowing the rela- tion of the meatus to the pubic arch, and possessing tact and experience, goes to it at once, the patient being on her left side, with the knees raised. In this way only one hand need be used. It scarcely need be said that the latter is the most perfect method of operating, and one which all should aim at being able to perform. Various circumstances alter the anatomical relations of the meatus and urethra. The meatus may be so flaccid and relaxed that it is found with difficulty; or after painful and lingering labors, the external parts may become so swollen from inflam- mation, and the effects of pressure, as to render it no easy mat- ter to find the urethra by the touch alone. In prolapsus, occur- ring during pregnancy, the direction of the meatus becomes altered so as to point towards the sacrum, or coccyx. In retro- version the meatus in drawn upwards, and the direction of the upper part of the canal is turned backwards and downwards, while in anteversion of the gravid uterus the urethra is dragged upwards; but the upper part of the canal is turned more for- wards than usual. In the unimpregnated state, the urethra is dis- placed by ovarian tumors, fibrous tumors of the uterus, and by the various alterations of position to which the uterus is liable. VARIETIES IN THE HYMEN. 53 Sometimes one of the mucous lacunae, close to the meatus, may be so enlarged as to admit a small-sized catheter, and the oper- tor may suppose he has reached the bladder, while the instru- ment is really in a cul-de-sac. The length of the urethra and the possibility of this mistake should always therefore be borne in mind. An inexperienced hand may pass the instrument along the upper floor of the vagina, but the sides of the urethra, or a slight clasping of the instrument by the canal, will generally assure the operator that he is in the right passage. The instruments used are, a common number 8 or 10 male catheter, with or without a stilette; a gum-elastic catheter very similar to the male catheter, except that it is somewhat shorter, and a flattened silver catheter. The stop of the silver catheter is perfect, and the urine can be drawn off by it without wetting the patient; but during labor, when this is not of so much con- sequence, a gum-elastic catheter is to be preferred, and if used without a stilette, it is scarcely possible for any accident to occur. It should be seen that the apertures of the catheter are free, and the point of the instrument should be dipped in oil or glycerine. The catheter should be held gently in the fingers, being lightly poised rather than grasped, and no force should be used, as both bladder and meatus have been perforated accidentally. It should be borne in mind that in case of difficulty it is far better to expose the patient than to use force, or incur the risk of injury. Immediately below the orifice of the meatus is the Ostium Vaginae, slightly oval in form, and of variable diameter, accord- ing to age, childbearing, etc. In the Virgin this opening is partly closed by a membranous fold, constituting the Hymen, which is commonly crescentic in form, the concave free border being turned upwards. Sometimes the hymen is deficient or wanting altogether, either congenitally or as the result of accident, so that its absence is no absolute proof of intercourse. In other cases it is circular in shape, or possesses several cribriform open- ings, or it may be thickened and imperforate. During inter- course this membrane is generally ruptured; but cases occur in which it is so strong and resisting, that surgical interference in the shape of a crucial incision is required. In some women, on the other hand, it is so distensible, that it readily yields, instead of tearing, and remains unbroken, even after perfect and habi- tual intercourse. This may account for the circumstance men- 54 ANATOMY OF THE VAGECTA. tioned by Parent Duchatelet, that in some prostitutes the vagina resembles the virgin state. Rupture of the hymen is by no means necessary to conception, as impregnation is known to occur through the cribriform hymen, or when only a very small aperture exists. Usually, after intercourse, the place of the hymen is occupied by several fleshy eminences, termed the Carnneulac Myrtifornies, which some anatomists believe to be formed by the cicatrization of the ruptured hymen, while others, as M. Rigaud, believe them to consist of reduplications of the mucous membrane, which exist before the loss of the hymen. There is a considerable amount of contractile tissue in the situa- tion of the carunculae, and in some cases the irritation and spas- modic painful contraction at this point is so great as to render intercourse difficult or impossible long after marriage. Externally to the carunculae, on each side, and on the surface of the nymphae, are two small openings, admitting the point of an Ancl's probe, which are the ducts of the Vulvo-Vaginal Glands. These glands, which were known to Bartholine and Duvernay, and called after their names, have recently been des- cribed with much accuracy and minuteness by M. Huguier. They are seated on each side of the vulva, outside and below the bulbi vestibuli, and in shape and size have been compared to apricot stones; their ducts are about half an inch long. The vulvo-vaginal glands secrete a clear albuminous mucus, of a pen- etrating odor during intercourse, which Huguier and Scanzoni believe can be ejaculated by the involuntary contractions of the neighboring muscles. These glands are considered the ana- logues of Cowper's glands in the male. M. Huguier points out that they may be the seat of abscess, or of encysted tumor, from obliteration of their ducts. ' The Perinaeum is the space between the posterior commissure and the margin of the anus. To the obstetrician the anatomy of this part is matter of great interest; though it must be con- fessed, that the anatomy of the male perinaeum has been culti- vated somewhat to the neglect of that of the female. In the ordinary state it is from an inch to an inch and a half in length but during labor it elongates to twice or four times this size. At the fourchette, the perinaeum is comparatively thin, but towards the anus it is of considerable thickness. It is com- posed chiefly of skin, cellular tissue, muscular fibres, and the PERLNEAL MUSCLES. 55 mucous membrane of the vagina. There are certain peculiari- ties in the arrangements of the muscles of the perinaeum which deserve notice. They are all inserted by at least one extremity into tendinous structures and fasciae. This occurs with the sphincter ani, levatores ani, coccygei, transversales perinaei, erectores clitoridis, and sphincter vaginae. The fibres of many of these muscles are indistinct as compared with other muscles, and are mixed up with a considerable quantity of elastic dar- toid tissue. These circumstances greatly facilitate the dilatation of the perinaeum at the time of labor. It must be borne in mind that the perinaeum has a two-fold function; one to dilate during the passage of the child; the other to support the pelvic viscera under other conditions. When its structures are rigid and undilatable, we have the danger of laceration; and when its dilatability is excessive, the patient is liable to prolapsus and other displacements of the uterus and vagina. A similar arrangement with regard to insertion holds good in the case of the abdominal muscles, and facilitates their distension by the gravid uterus during pregnancy. (Fig. 10.) Fia. 10. 1, Sphincter Ani; 2, Tendinous point of Perinasum; 3, Sphincter Vaginas; 4, Transversus Perinasi; 5, Hrector Clitoridis; 6, Aponeurosis: 7, Levator Ani; 8 Gluteus-maximus. TU Vagina extends between the internal and external parts of gelation ; but as it is concerned with the latter in coitus, and bea-s no share in the development of the ovum, it may be conveniei-tly described with the external organs. This canal is 56 SIZE OF VAGINA. slightly curved, the concave surface being upwards and forwards, and its direction is nearly that of the outlet, and lower portion of the middle, of the pelvis. The anterior wall of the vagina is about four inches long, the posterior being five or six inches in length. This is partly on account of the greater length of the lower curve, and partly because of the way in which the uterus is inserted into the vagina. The axis of the uterus is nearly the same as the axis of the inlet of the pelvis, so that the uterus is inserted, as it were, into the anterior wall of the vagina, while the posterior wall is prolonged behind the os uteri. This canal is longer in virgins than in women who have borne children, par- ticularly multipara?. It is also longer in the middle months of pregnancy than in the beginning, or towards the termination of gestation. It is elongated in some cases of fibrous or ovarian tumor, when the tumor is supported above the brim of the pelvis, and raises the uterus with it. The diameter of the vagina varies in different parts of the canal, being smaller at the outlet than in the middle and upper portions. In ordinary cases, the sides of the vagina are in contact; and this acts as a valvular arrangement for preventing the access of air to the uterus. As regards structure, the vagina is composed of an ex- ternal, middle, and mucous coat or tissue. The external layer consists of cellular tissue, which connects it anteriorly with the bladder and urethra; laterally with the levatores ani, and pos- teriorly with the rectum and the peritoneum. The connection with the peritoneum is in the upper and posterior fourth of the vagina, where the peritoneal cavity dips down between the vagina and the rectum. The middle coat is dense and fibro-cel- hilar, and is similar in structure to the proper uterine tissue, with which it is continuous at the os and cervix uteri. It has been compared by Cruveilhier and other anatomists to the dartos. During pregnancy, it partakes of the growth of the uterine muscular tissue, though in a less degree. The mucous lining of the vagina has upon the mesial line of its anterior and posterior surfaces two ridges, termed the columnae ru^aruro. From these two columns folds of mucous membrane project at nearly right angles, the folds being most numerous at the lcvver part of the passage. The rugae of the vagina are most distinct in virgins, less so in women accustomed to intercourse, aid they nearly or altogether disappear in women who have bor*e child- SECRETIONS AND FUNCTIONS OF THE VAGINA. 57 ren. The vagina also becomes smooth in virgins after the time of childbearing has passed. The objects of the rugae are to yield an extensive surface for sensation, and to provide for the distension of the canal during labor. Examined microscopically, the vaginal mucous surface is found to be studded with vascular papillae, which have been described and figured by Dr. Franz Kilian, and which are probably the seat of the great sensibility of the organ. The whole surface is covered by a thick layer of tessellated or squamous epithelium. Writers on the subject gen- erally describe the vagina as containing great numbers of*mu- cous follicles, which are supposed to secrete the mucus which lubricates the vagina at ordinary times, and especially at the time of parturition. In my own examinations, I failed to find any large number of glands, except at the outlet of the vagina; and with this exception, the mucus of the vagina is, I believe, produced by the epithelium, and consists of plasma and epithe- lial particles. The secretion of the vagina, as pointed out by M. DonnC", and Dr. Whitehead, of Manchester, is distinctly acid. The acid secretion is believed to be serviceable in preserving the fluidity of the menstrual secretion, and thus of facilitating its escape from the vagina. It has also an antiseptic effect, and tends to prevent the decomposition of coagula. It likewise con- tributes, with the rugae of the vagina, to stimulate the penis dur- ing coitus. Besides the coats of the vagina already described, it is surrounded, particularly near the outlet of the passage, with a plexus of veins, resembling erectile tissue ; and it posses- ses a muscle, the sphincter vaginae, arising from the tendinous point of the perinaeum, inclosing the bulbi vestibuli, and in- serted into the clitoris. A fasciculus of the muscle crosses the vena dorsalis, and aids in promoting the turgescence of the cli- toris. The arteries of the vagina are branches of the internal iliac, and the veins empty themselves into the internal vein. It derives its nerves from the hypogastric plexus, and from the third and fourth sacral nerves. The vagina resembles skin almost as much as mucous mem- brane, and in cases of procidentia, where it is exposed, it be- comes converted into dermoid tissue. The chief functions of the vagina are as an organ of sensation and introception, and as a canal for the passage of the foetus and the catamenial secretion. It undoubtedly possesses some contractile power, both voluntary 5g PHYSIOLOGY OF COITUS. and reflex. This is seen in the expulsion of coagula during men- struation, and after parturition, and on the introduction of the speculum. The vagina also contracts with considerable force during the passage of the child, and it sometimes expels the pla- centa after labor. It may be necessary to say a word respecting the physiology of Coitus, as regards the female. The sexual orgasm of the male is well recognized. We know that it begins with excitement of the glans penis, and ends in spasmodic contraction of the vesi- culae'seminales and ejaculatores muscles, this contraction being attended by the sensorial orgasm. The female is considered " passive," both by Professor Muller and Dr. Carpenter, during coitus, but this is a great mistake. The sexual " paroxysm " in the female was fully recognized by John Hunter, and is as dis- tinct as that of the male. It begins in the clitoris, and ends in an orgasm or paroxysm of sensation. Whether the sensation produces any spasmodic reflex action is a question. Is the ejac- ulation of the secretion of the vulvo-vaginal glands described by M. Huguier, the analogue of emission in the male ? Whytt and the older anatomists believed in the contractions of the Fal- lopian tubes during intercourse. Of the existence of the sen- sorial orgasm there can be no doubt, and its absence constitutes impotence in the female. It should be observed, however, that the orgasm is not at all necessary to conception. Women to wdiom Heberden applied the term " frigida " conceive as well as those who are perfect in this respect. Impregnation consists in the meeting of the spermatozoa and the ovule, and can never take place at the moment of coitus. The union of the male and female elements of reproduction in the uterus or Fallopian tubes is no more attended by sensation than the conjugation of the OregarincB. An account of the external organs of generation would not be complete without a description of the Mammae from which the infant derives its nourishment for some time after birth. The mammary glands are placed upon the pectoralis major muscle on each side, extending from the third to the seventh rib. This situation, which is in great measure peculiar to the human fe- male—the mammae being, in the vast majority of animals placed upon the abdomen—is evidently adapted to the nursino- of the infant while supported in the arms of its mother. Theso 1 ANATOMY OF THE BREAST. 59 glands are hemispherical in shape, the external aspect being con- vex, the posterior, flat or slightly concave. The left breast is generally the larger of the two, and is more used in nursing. Each gland is enveloped in a fibrous or dartoid capsule, which dips down between the various portions of the gland, and is sur- rounded by a considerable quantity of adipose tissue. The intimate structure of each gland consists of numerous lobes, which are divisible into smaller and smaller lobuli, until we arrive at the ultimate follicles of which the substance of the gland is composed. The follicles and ducts are covered with a layer of epithelium. It is by the growth and multiplication of the nuclei, and the bursting of the epithelial cells, which have been found by Professor Goodsir to be filled with milky fluid, that the lacteal secretion is produced. These follicles or vesi- cles, having caecal extremities, empty themselves into small tubes, which unite with each other, and proceed in a tortuous course towards the centre of the gland, becoming larger and larger, and terminating in from ten to fifteen galactophorous tubes, which are collected together, but without much inoscula- tion, near the base of the nipple. As they approach the nipple, they dilate, to form sinuses or ampullae, which act as reservoirs for the milk. Underneath the nipple they contract again, and pass by separate ducts to the surface of the mamilla, where their openings are found in depressions of the mucous membrane. The lactiferous tubes are wanting in valves, but are closed at their external apertures. The surface of the gland is covered by delicate integument, and at its summit is placed the nipple, which in the virgin, or in women who have not borne children, is conoidal in shape, but in nursing women assumes a flattened or cribriform appearance at its extremity. The site of the nipple is on a level with the fourth rib. This, the most vascular part of the breast contains a certain quantity of erectile tissue, which makes the nipple tur- gid, and tends to dilate the openings of the milk-ducts, under irritation. The turgescence is generally accompanied by plea- surable sensations, the surface of the nipple being covered by numerous nervous papillae. The sensation of "the draught," which is excited by emotional causes, the suckling of the child or, as a reflex action, by the ingestion of blood, or drink into the stomach, and is felt in the nipple, and is fol- 60 THE AREOLA. lowed by a rapid secretion of milk. The nipple contains a considerable quantity of dartoid contractile tissue, which is probably concerned in the closure and dilatation of the milk ducts. The action of this tissue and the capsule covering the gland contributes to the expulsion of the milk. The base of the nipple is surrounded by an areola of a pinkish hue in the vir- gin, but in the pregnant woman pigment cells are deposited in it, and the areola becomes darker in color. On the surface of the areola are numerous small tubercles, or sebaceous glands, which secrete a fatty matter, intended to defend the nipple dur- ing lactation. Sudoriferous glands are also found upon the areola. The mammary glands receive their supply of blood from the thoracic intercostal, internal mammary, and epigastric arteries. The veins are those accompanying these arteries. Around the nipple, the veins are arranged in a circular manner, the circulus venosus of Haller. During pregnancy, as Mr. Nunn has pointed out, owing to the interference with the internal circulation by the pressure of the gravid uterus, the circulation through the internal Tig. 11. 1, Galactophoroua ducts. 2, Lobuli of the Mammary Gland. mammary and epigastric arteries, and the veins of the surface of the abdomen and thorax, is very much increased—a mechanical LYMPHATICS OF THE BREAST. 61 condition which probably contributes to the development and sup- ply of the gland during gestation. The nerves are chiefly branches of the intercostals. The lymphatics are very numerous, and maintain connections with the lymphatics of the axilla, anterior and posterior mediastinal, and other parts. These lymphatics are believed to absorb the watery portions of the milk when first secreted, and it is to these vessels that we address ourselves when we endeavor to diminish the quantity of the milk by fric- tions. LECTURE III. THE INTERNAL ORGANS OF GENERATION. Gentlemen :—The Uterus is, in an obstetrical sense, by far the most important of all the organs of generation. It is in this viscus that the ovum is received, retained, and nourished until the foetus becomes fitted for extra-uterine existence, and to the physiological action of this organ its expulsion at the end of utero-gestation is mainly due. The following description will have reference chiefly to the unimpregnated uterus. In shape the Virgin or Nulliparous uterus is pyriform. Dubois describes it as a cone compressed from before backwards, and compares it to a flattened calabash, the base of which is directed upwards, and the orifice downwards. The uterus is placed in the middle of the upper part of the pelvis, its direc- tion being the same as that of the pelvic inlet. It is situated above the vagina, and below the ilium, having the bladder in front, and the rectum behind it. Thus the inferior part of uterus has a vaginal, and the upper part a peritoneal aspect. The lower part of the organ consists of the Os uteri, possessing an interior and posterior lip, and constituting the outlet of the uterus as regards the catamenial secretion and the products of impregnation; and its inlet, with respect to coitus, and the fer- tilization of the ovum. Above the os uteri is situated the Cervix, and the highest part of the uterus is called the Fundus, the upper and middle portion being termed the Body. The cervix and body contain a canal and cavity, but the great bulk of the organ consists of its walls, which are of considerable thickness. The external surface of the uterus is in part covered by mucous membrane, and in part by peritoneum, the rest of its superficies being occupied by attachments to other organs. The uterus is from two and a half to two and three quarters of an inch in length its breadth being, from one Fallopian tube to another, about an C2 VIRGIN CERVIX UTERI. 63 inch and a half, or an inch and three quarters. At the cervix the breadth of the uterus is about an inch. From before back- wards its greatest diameter is about an inch, and the greatest thickness of its parietes, which is in the middle of the body, is about half an inch. The anterior surface of the uterus is some- what flattened, the posterior being convex. The os uteri is circular or somewhat oval in form, its trans- verse diameter being generally greater than the antero-posterior. Of the two lips of which it is composed the anterior is the low- est, so that it hides the posterior lip as well as the orifice. The fis- sure itself is, in the nulliparous uterus, not circular, but trans- verse, the external angles of the rima being directed backwards, like the mouth of a fish. It is from this peculiarity that it de- rives its name of os tincoe. The canal of the cervix is fusiform in shape. There is a slight constriction at the os uteri, and a more considerable narrowing of the canal at the os uteri internum, or the point at which the canal of the cervix enters the cavity of the body. The cervical canal is flat- tened from before backwards, and is about an inch and a half in length. It is lined by the mucous membrane, which is arranged in a peculiar manner. When the cavity of a virgin cervix uteri Eig. 12. 1, Cavity of the body; 2, Canal of cervix; 3, Opening of Fallopian tukes; 4, Penniform rugae : 5, Os uteri internum; 6, Fundus. is laid open, the internal surface is generally found to contain four columns of rugae, arranged more or less in a transverse direction. The reduplications of the cervical mucous membrane may be 64 ANATOMY of cervix uteri. compared to an open book, and the names penniform rugae, pal- mae plicatae, and arbor vitae internus have been applied to them. These rugae are separated by four grooves or sulci, two of which divide the anterior from the posterior walls ; the other two, which are most marked, being upon the median line in the anterior and posterior walls. There are from ten to fifteen rugae in each column. These rugae, and the spaces between them, are everywhere covered by such multitudes of mucous cysts or follicles, that, on a moderate computation under a power of eighteen diameters, ten thousand mucous follicles are visible in a well-devoloped nulliparous organ. The cervix uteri may in effect be considered as an open gland. The rugae are evidently a provision for the dilatation of the mucons membrane in the latter months of pregnancy, and during parturition. They also pro- vide an extensive secretory surface. The objects of the secre- tion are to keep the cervix uteri impermeable in the ordinary state, to provide a fit medium for the ascent of the spermatozoa, to furnish the plug which fills the cervix during pregnancy, and to secrete the mucus which lubricates the os uteri and vagina during labor. The secretion consists of mucous corpuscles and plasma, having a distinct alkaline reaction, while the secretion of the external portion of the os is decidedly acid. The limits of the acid and alkaline secretion-are determined by the presence of squamous or cylindrical epithelium. Fie, 13. The cavity of the body of the nulliparous uterus is triangular in shape, the base of the triangle being above and the apex below, At the two superior angles, the Fallopian tubes enter the uterus, MUCOUS MEMBRANE OF THE UTERUS. 65 while at the inferior angle the canal of the cervix communicates with the body of the organ. The angles leading to the Fallo- pian tubes are grooved; and at the middle of the triangular space the anterior and posterior walls of the body of the uterus project internally. The thinnest part of the walls of the uterus is at the entrance of the Fallopian tubes : the thickest is at the middle part of the fundus, and the parietes of the body oppo- site the middle of its triangular cavity. Perhaps the most remarkable structure of the uterus is the mucous membrane which lines the cavity of its body. It is, in the healthy condition, pale in color about a line in depth, and forms a thin layer, one aspect of which is free, the other being closely united to the proper tissue of the walls of the uterus. If the surface of the unimpregnated womb be examined with a Fig. 14 A, Uterus laid open; 1, Mucous membrane of uterus; 2, Substance of the uterine walls. B, A single gland from the mucous membrane of the uterus; 1, Caecal extremity"; 2, Mouth of the gland. lens, numerous points are visible, which are openings of the glands of the mucous membrane. The openings are given by Kolliker as one-thirtieth of a line in diameter. These glands are tubular, and slightly coiled upon themselves, closely resem- QG PAPILLA OF THE OS-UTERI. bling the glands of Lieberkuhn in the intestine. Their general arrangements, and that of the connective tissue around them, is concentric, the open mouth of each gland being upon the sur- face of the mucous membrane, and its caecal portion deeply seated in the attached surface. Sometimes the utricular glands are double, or two glands may open upon the mucous surface by the same outlet. These glands are supposed by some to secrete mucus. Dr. West, for instance, supports the view that in Jeucor- rhcea much of the discharge is, in certain cases, derived from these glands. Some believe they secrete the nfenstrual fluid. Others affirm that they elaborate the material out of which the deci- dua reflexa is formed. The latter, which is the opinion of Professor Goodsir, Dr. Sharpey, and Kolliker, is probably the correct one. The mucous surface of the uterus is covered by an epithelium. In the cavity of the body this is cylindrical and ciliated. The cilia vibrate from below upwards, and probably assist the ascent of the spermatozoa. In the cervix, the cilia are not alwayTs pre- sent, and at the margin of the os, at the lowest part of the canal of the cervix, the cylindrical epithelium ceases, the whole of the vaginal aspect of the os and cervix being covered by squamous epithelium, similar to that of the vagina. Underneath the epithelium, club-shaped papillae or villi are everywhere found. Each villus consists of one or two looped bloodvessels and a cel- lular envelope, the whole being covered by epithelium. These villi are larger within the os uteri than upon its external surface, but they are less numerous in the upper part of the cervical canal, and the cavity of the body. At the os uteri these papillae appear to possess special sensation of a sexual character. It is also probable that they play a part as excitors of reflex and peristaltic action. According to the recent researches of Kolliker, Kilian, Mr. Rai- ney, and others, the substance of the uterus is made up of connec- tive tissue and a vast number of fusiform fibre cells, fibre o-erms, or embryonic nucleated cells, having the power of development into non-striated involuntary muscular fibres. The diameter of these cells is about * oVoth of an inch, and their length is some- what greater, so that they are slightly elongated in shape. In the unimpregnated uterus, under ordinary circumstances, the fibre cells or germs remain quiescent, and are not the subject of any increase in size. On the occurrence of impregnation, the WEIGHT OF UTERUS. 67 growth of a polypus in the uterus, or auy continual irritation of Hie cavity or walls, the embryonic fibre cells commence a career of growth and multiplication. These fibre cells are of great importance, as it is entirely to their development that the gravid uterus owes its contractile properties. They may be compared to the derivative germ cells by which lost parts are reproduced in the lower animals, and which, but for the loss which calls forth their development, would forever remain inactive. In the case of the uterus, unless impregnation or some other stimulus be applied, these germ fibres remain through life in a rudimen- tary state. In the unimpregnated condition, it is probable that the germ fibres or fibre cells are in a more advanced state in some uteri than others, particularly in multipara. Cases are met with in which the uterus expels coagula, or the dysmen- orrhoeal membrane, by contractile efforts, even in the unimpreg- nated condition. It is probable that, by relaxation of the fibre cells of the os and cervix, and contraction of those of the body, the os uteri may be opened and matters expelled from the cavity of the virgin uterus. The difference between the virgin or Nulliparous uterus and the Multiparous organ have been very strongly insisted upon by M. Paul Dubois. The term nulliparous is evidently to be pre- ferred to that of virgin uterus, as intercourse without impregna- tion exerts no influence upon the anatomical characters of the or^an. In the multiparous uterus the anterior and posterior sur- face of the body is more rounded. The fundus, instead of being flat, is convex, so that there is a considerable protuberance above a line drawn from tube to tube. The vaginal portion of the neck is altered, being more conical and elongated. The os uteri, instead of presenting a transverse fissure, is rounded or puckered in shape. The depression felt by the finger is more evident, and the orifice is considerably larger. These changes in the os uteri are most evident in women who have borne large families. They are imitated to a slight extent in nulliparous women who have been subject to inflammatory conditions of the os uteri, dysmenorrhea, polypus, or any of the conditions which excite the growth of the organ. The uterus which has been fully developed by gestation never returns, unless as a morbid condi- tion, to the size of the nulliparous organ. Meckel gave the weight of the nulliparous organ at seven or eight drachms, and 68 6HAPE OF THE CAVITY OF THE UTERUS. the multiparous at an ounce and a half. The diameters are all increased in the multiparous organ. The interior of the uterus also offers some remarkable differences in the two organs. The cavity of the bodyT of the multiparous womb is considerably enlarged. The os uteri internum is less distinct, and the canal of the cervix is shorter, the penniform rugae being to some extent obliterated. The cavity of the body, instead of being distinctly triangular, is oval in shape, the angles into which the Fallopian tubes enter having entirely disappeared. These changes are not without practical importance. Their consequence is obvious in a medico-legal point of view. A few years ago a lady of family Fig. 15. Section of the Nulliparous and Multiparous uterus. and her maid were burnt to death together in a hotel at the West-end. The bodies were so mutilated as to render any recognition by external signs impossible; but the lady had borne a numerous family, and the identity of her body was ascertained from the condition of the uterus. Again, in the return of the uterus to the unimpregnated state after parturi- tion, the involution of the organ may be so excessive as to pro- duce amenorrhcea and sterility, or which is more frequent, it may be incomplete, and give rise to monorrhagia. The uterus is supplied with blood by four arteries, the two ovarian, or spermatic, and the two uterine. The upper part of organ is supplied by the ovarian, and the lower by the proper uter- BLOOD VESSELS AND LYMPHATICS OF THE UTERUS. 69 ine vessels. In the substance of the uterus they run a very tor- tuous course, anastomosing very frequently. The veins corres- pond to the arteries. Their walls are very thin in the uterus, , Fig-. 16. External view of the Nulliparous and Multiparous uterus. and they possess no valves. They communicate with the veins of the bladder and vagina, and empty themselves into the iliac and ovarian veins. The lymphatics are numerous but of small size before impregnation, and chiefly enter the lumbar glands. The uterus is principally supplied with nerves by the hypogastric and sacral nerves, and by branches from the ovarian plexus; but I propose to enter into the question of the nervous supply of the uterus when I come to treat of the increase of the various tissues of the gravid uterus, and of the motor endowments of the parturient organ. The Fallopian Tubes extend on each side from the upper angles of the uterus towards the brim of the pelvis. Each tube is from four to five inches in length. The first direction is upwards and outwards; it then passes downwards, backwards, and inwards. The tubes can be felt as a cord-like structure in the broad ligament, the uterine half being thicker than the exter- nal or ovarian half. They are pervious throughout, the diameter of the canal being smallest at the uterine extremity. At the entrance to the uterus it, however, readily admits a fine whale- bone stilette. At the distal extremity, or ostium abdominale, 70 FUNCTIONS OF THE FALLOPIAN TUBES. each tube terminates in the corpus fimbriatum—a fringe-like structure, which may be compared to the tentacles of a polyp. In the centre of the circular fringe is seated the ovarian aper- ture of the tube, considerably larger in size than the ostium uterinum. One of the fringes, or a separate ligamentous band, generally connects the Fallopian tube with the ovary, but the aperture and the general mass of the corpus fimbriatum floats loosely in the neighborhood of the ovary. The internal sur- face of the tubes is lined by the mucous membrane of the uterus.' It is thrown into longitudinal folds, so as to admit of dilatation, and is covered by ciliated cylindrical epithelium, the movements of the cilia being from the ovarian towards the uterine extre- mity. The mucous membrane of the tubes is thin, and devoid of villi or glands. The middle coat of the Fallopian tubes is continuous with the middle coat of the uterus, the fibres being more developed, and arranged as an external and longitudinal, and internal and circular layer, fitted for the vermicular or peris- taltic movements which the tubes are called upon to perform. These layers are intermixed with connective tissue, similar to that found in the stroma of the ovary and the middle walls of the uterus. The external surface of the tubes consists of the peritoneal folds, constituting the ligamenta lata. (Fig. 17.) Fig. 17. [he uuirapregnated uterus, ovaria, and Fallopian tubes. * Round Ligaments. As regards the function of the tubes, the ciliary currents and the muscular contractions combine to convey the impregnated or un- impregnated ovum from the ovarium to the uterine cavity. The tubes are really to be considered as the oviducts of the human eco- nomy. When they fail of their office in the impregnated condi- tion , we have extra uterine gestation as the result. There is scarcely SITUATION OF THE OVARIA. 71 anything more mysterious in the range of physiology than the grasping of the ovary by the fimbriated extremity of the tube where there is an impregnated ovum to be conveyed to the uterine cavity. At the time of impregnation there is not merely a grasping of the ovary but the tube must be applied to pre- cisely the spot upon the ovarium from which the ovulum is about to emerge. How is this selection to be accounted for ? It is evidently one of those reflex actions in which excitor and reflex stimuli are in such exact and exquisite relation as to stimulate the perfect effects of volition. Perhaps it is not more wonderful than what occurs in the case of the polyp. When a particle of food is placed on any part of the surface, the filaments of the oral fringes turn with precision to the foreign matter, and grasp it for convey-- ance to the interior of the animal. It appears either as though the different parts of the ovary were in exact relation with the corpus fimbriatum, or that when the ovarian stimulus has excited the fringes to contractions upon the ovarian surface, only that part of the ovary is firmly grasped which is in a state of irritation, such as that which attends the maturation or escape of an ovulum. During menstruatren, the Fallopian tubes have been found firmly- grasping the ovaria by Gendrin and other observers. The embrace of the ovaria is favored by the turgescence and rigidity which the tubes assume under excitement, as observed by Cruikshank, and which directs them towards the ovaria. The Ovaria are the analogues of the testes in the male, and constitute the dominant organs of the female generative system. They are two flattened bodies, somewhat oval in form, or tend- ing to a crescentic shape. Their length is considerably greater than their breadth, but the upper surface is slightly convex, and the lower somewhat concave. They are situated in the posterior fold of the broad ligament, and behind the Fallopian tubes. The ovaria are about half an inch thick, three-quarters of an inch wide, and from an inch to an inch and a half long. They are connected, as already mentioned, to the corpora fimbriata, and a ligament attaches them to the uterus, near the insertion of the Fallopian tube. This ligament, the Ligamentum Ovarii, con- nects the stroma, or parenchyma, of the ovarium with the pro- per tissue of the uterus. These organs are entirely covered by peritoneum, except at the hilus, where the nerves and vessels enter, but are directly enveloped by a white fibrous tunic, the 72 CONTENTS OF THE OVARIA. tunica albuginea, analogous to the membrane of the same name in the testis. The tunica albuginea incloses the proper struc- ture or stroma, of the ovary, which is reddish-white in color, and similar in constitution to the proper fibrous structure of the uterus. Scattered about in the stroma of the ovary, but parti- cularly towards the external surface, numerous small vesicles are found, varying in size from a pin's head to a small pea. These are the Graafian vesicles, or follicles, as they should more properly be called. There are generally from ten to twenty, or more, in, or near, a state of maturity; but a far greater num- ber of small vesicles are visible by the aid of the microscope, and are constantly passing on to maturity to replace those lost by the periodical rupture of the most advanced follicles. The ovaria must be considered as two follicular glands. Each Graafian fol- licle represents the ultimate tubule, or follicle, of a secreting gland, from which it differs only in being closed, except at the time when it discharges its contents. This tendency to the for- mation of closed vesicles, or follicles, extends to other parts of the generative system. It is met with in the Fallopian tubes, in the cavity of the body and cervix, at the os uteri, as in the case of the Nabothean follicles,.and even in the vagina. The minute anatomy of the Graafian follicles will be given in a subsequent lecture, in connection with the subjects of ovulation and men- struation. The ovaria are supplied with blood by the spermatic and uterine arteries, which enter at the lower border, and after numerous divisions, take a serpentine course in the stroma, and are distributed to the tunica albuginea, the stroma, and the walls of the Graafian follicles. The veins follow the same course, arid empty themselves into the uterine and internal spermatic veins. The lymphatics are few in number. The nerves are fibres derived from the renal and spermatic plexuses. Fi&. is. (Section of Human Ovary showing the formation of Graafian follicles. Twice the natural s'' UTERINE LIGAMENTS. 73 The lower part of the uterus is attached to the bladder and rectum by folds of the peritoneum, which are sometimes called the Anterior and Posterior Uterine Ligaments. The peritoneum, reflected upwards, covers the anterior and posterior surfaces of the uterus, inclosing the organ between two layers of this mem- brane. These layers meet together at the sides of the uterus, and pass off* to the lateral walls of the pelvic cavity, dividing the pelvis transversely. In this way, the peritoneum forms the principal part of the Broad Ligaments of the uterus. The fibrous or muscular structure of the uterus itself also extends into these ligaments. They contain besides, the Fallopian tubes, the ovaria, the Round Ligaments, with bloodvessels, nerves and lymphatics. The round ligaments arise from the upper angles of the uterus, in front of the Fallopian tubes. From this origin, each ligament passes to the inguinal ring, descends the inguinal canal, turning round the epigastric artery, and its fibres are inserted into, or united with, the structures of the mons veneris. The length of the round ligament is from four to five inches. The external transverse fibres of the proper substance of the uterus are prolonged into the round ligaments, of which they form a constituent part. Some fibres of the internal oblique muscle also.enter the lower part of the canal, and extending upwards, contribute to the formation of the ligament. The ovaria have been shown to be connected with the uterus, at the point of insertion of the Fallopian tubes, by a fibro-cellular cord or ligament, prolonged from the proper substance of the uterus. Thus the fibroid embryonic muscular tissue of the uterus is continued from below into the vagina, and above into the ovaria, Fallopian tubes, and the broad and round ligaments. This arrangement probably facilitates the great displacements of the vagina, tubes, ligaments, and ovaria, which occur physiolo- gically during the growth of the gravid uterus. The growth of the muscular tissue in these several parts allows of their elonga- tion without injury or rupture. [ The student will be enabled to get a better idea of the rela- tive position of the organs in the recent pelvis of the virgin, as represented by Dr. Kolrausch. The subject was a young girl of 21 years of age, who committed suicide while menstruating. The specimen was prepared in such a way as to enable Dr. Kol- 74 RECENT PELVIS OF THE VIRGIN. rausch to see it while lying in a bath of alcohol, covered with a glass plate ; looking downward through a diopter, firmly fixed 24 inches above the glass plate, he used a pen dipped in prin- ter's ink, softened with oil of turpentine, and drew every one of the lines with the utmost exactness on the intervening plate of glass—seeing them through the diopter; so that they could not, perhaps, be more correctly taken by a photograph. The cop- per-plate was copied from the drawing. To the right is the buttock, (1) covered with the bisected sacrum RECTO-VAGINAL SPACE. 75 (2), in front of which is the rectum (3), which has been opened by the incision. In the left, behind the os pubis (4), is the blad- der (5) with its urethra (6). Between the bladder and the rectum is the tube of the vagina (7), surmounted by the uterus (8). whose summit or fundus does not rise quite so high as the plane of the superior strait. The womb rests upon the upper end of the vagina, which incloses its cervical or neck portion, and keeps it up in its place by means of its connection with the bladder in front and the rectum behind, and more than all by means of two utero-sacral ligaments, which tie the upper ends of the vagina and womb to a certain place about an inch and a half in front of the apex of the sacrum. I may here say, that as long as the utero-sacral ligaments remain in a healthy state, preserv- ing by their tone a due length, the womb cannot fall down- wards or prolapse, because the cervix, being inclosed within the upper end of the canal of the vagina, it cannot move down unless the upper end of the vagina moves down also. Douglas's cul-de-sac (9) is a deep pocket between the gut and the womb, sometimes increased by frequent coition, and especially observable in prostitutes, to double or triple its natural length, as here represented. It is into this place into which the fundus uteri falls when it is quite turned over backward or retroverted. Let the student, therefore, comprehend that the posterior wall of Douglass cul-de-sac is the rectum and sacrum ; its anterior is the womb and upper posterior end of the vagina, and its right and left walls, the right and left utero-sacral ligaments. I wish him to understand this on account of its importance in retroversio uteri and in prolapsus of the bowels ; but also from the danger in passing the blade of a forceps behind the os uteri through this " recto vaginal space," into the cavity of the peri- toneum, almost certainly producing the death of his patient. It is through this " space," that Dr. Sims has passed a catheter for the purpose of drawing off the fluids effused and creating irritation after operating for the radical cure of ovarian dropsy. Most plates intended to represent the inner female genetalia in situ exhibit the fundus uteri on a level with or above the plane of the strait. Kolrausch's drawing is the most beautiful and correct that has yet been produced, and gives to all the inter- nal organs their absolute right place.] LECTURE IY. OVULATION. Gentlemen :—The mature Graafian follicle is about the size of a small pea. It is formed of two layers—one internal and fibro-cellular in structure ; the other external and vascular, con- sisting of the condensed ovarian stroma. The external surface of the ripe vesicle is also covered by the indusium of the ovary. It is the internal membrane which forms the proper ovisac. The ovisac is lined by a granular layer of epithelium. Altogether, the envelope of the follicle may be considered as a mucous membrane, and the Graafian follicles constitute the mucous fol- licles of the ovarian glands. Graafian follicles appear in the ovary at or soon after birth, being at first small, and distributed throughout its structure; but they gradually increase in size, and at puberty the largest follicles are found upon the surface of the organ. From this time to the decline of the catamenia a succession of Graafian follicles ripen and find their way to the surface of the ovarium, when they rupture and discharge their contents, chiefly at the catamenial periods. Each follicle con- tains a clear fluid, similar to the serum of the blood, in which are granular particles and nuclei derived from the epithelial lining. When De Graaf, of Delft, in Holland, described, in 1673, the follicles, which have since borne his name, they were supposed to be the actual ova of mammalia, though anatomists were at a loss to account for the small size of the impregnated ova occasionally found in the uterus and Fallopian tubes, as compared with the ovarian vesicles themselves. But in 1827, Von Baer, of St. Petersburg, discovered the true Ovule within the Graafian vesicle, and since that time the relations of the ovule to the other contents of the ovisac have been carefully examined by many distinguished anatomists. I may here men- tion that, in speaking of the unimpregnated state, it will be 76 ANATOMY OF THE GRAAFIAN FOLLICLE. 77 more precise to use the word Ovule, or Ovulum, reserving the term Ovum for the ovule after the occurrence of fecundation. It may also be observed that a close analogy exists between the ova of all animals, so that observations made upon one class of animals have a general application, and the history of the human ovule has been made out partly by the study of the ovule in the human female, and partly by the light thrown on the subject by researches in comparative anatomy. At first, and while the Graafian follicle is imbedded in the ovary, the ovule is found in the centre of the vesicle. At this time the semi-transparent and albuminous matter and granules contained in the follicle have the following arrangement. The granules are accumulated in the form of a layer on the internal surface of the ovisac, so as in a great degree to resemble an epithelial lining. This layer has been termed the Membrana Granulosa. Immediately surrounding the ovule, another granular layer is found, which has been called the Tunica Granulosa. Passing between these two layers are certain granular bands constituting the Retinacula which retain the ovum in its place. When the follicles mature and approach the ovarian surface, the ovules also rise towards the free surface of the follicles, as Dr. Martin Barry believed by the contractions of the bands of the retinacula on the superficial aspect of the vesicle ; while the membrana granulosa and tunica granulosa now become fused together near the surface of the Fiq. 19. Section of two Graafian Follicles enlarged about eight diameters, p. Peritoneal covering; s t, Ovarian Stoma; o v, the two Layers of the Ovisac; m ff, Membrana Granulosa, or epithelial lining of the Ovisac. Around the ovum this membrane is seen forming the Proligerous Disc. ovisac. The ovule thus becomes imbedded in an aggregation of granules, which is named the Cumulus Proligerus, or prolig- erous disc. If the Graafian follicle were spread out, we might 78 VESICLE OF PURKINGE. consider the ovule as lying upon the surface of a mucous mem- brane, and enveloped in an accumulation of granular or epi- thelial matter. Passing to the description of the ovule itself, it is found to measure about 2^„th of an inch in diameter, and to consist of an external membrane,Zona Pellucida, or vitellary membrane, a vitellus or yolk, and a cell, which is termed the Germinal Vesicle or germ cell. As regards size and position, the germi- nal vesicle tears much the same relation to the ovule as the ovule does to the Graafian follicle. The yolk of the mammifer- ous ovule is very small, as compared with the yolk of birds and amphibia. In the mammalia, the yolk consists of elementary granules, all or nearly all of which are exhausted in the early germinal processes of the ovum after impregnation has taken place ; while in the ovipara the yolk is composed of two kinds of material, the one consisting of granular particles, similar to those of the mammalian ovule, and termed the Germ Yolk; the other, and larger portion, of fat globules, intended for the nutrition of the ovum during incubation or early development, and termed, in contradistinction to the former, the Food Yolk. The germinal vesicle was first discovered in the ovule of the bird by Purkinje, of Breslau, in 1825, and when the mammalian Fig. 20. ovule became known, the vesicle of Purkinje was soon sought for, and found by M. Coste. In man and mammalia, the germinal vesicle is about the one-sixtieth of a line in diameter. Within the germinal vesicle itself is contained another important element of the reproductive process. In 1835, Rudolph Wagner, of Gottingen, and Mr. Wharton Jones, in this country, discovered con- temporaneously, a nucleus or collection of fine granules in the interior of the germinal vesicle, which has been called the Mac- ula Germinativa, or germinal spot. In some animals the macula is nuclear in character, while in others the germinal spot consists of a mass of small granules. This addition to our know- ledge of the ovule brought the germinal vesicle within the category of ordinary nucleated cells. The macula germinativa is the nucleus or centre of the whole of this wonderful organism, and it may be useful to trace the anatomy of the nature of a mature Graafian follicle from within GLANDULAR STRUCTURE OF THE OVARY. 79 outwards. Surrounding the germinal spot, we have the germi- nal vesicle. On the outside of the o-erminal vesicle there is the yolk, inclosed in the vitellary membrane. These structures, taken collectively, constitute the ovule. The ovule itself is con- tained in the Graafian follicle, but it does not remain in its cen- tre, this being occupied by the liquor folliculi. The ovule is seated in a cumulus, or mamelon of granular epithelial matter, constituting the proligerous disc, and forming part of the lining membrane of the follicle. On the outside of this membrane there are the fibro-cellular and vascular layers of the follicle; and lastly, upon its free surface, the indusium, or ovarian por- tion of the peritoneum. When the Graafian follicle is ready to shed the ovule, it pro- trudes slightly above the surface of the ovary, and the rupture of the follicle is apparently caused by an increase of the liquor folliculi, or fluid secreted by the epithelial lining of the ovisac. The gradual distension of the follicle causes a thinning of its fibrous and vascular walls, and of the indusium, un- til at length it bursts. The ovulum has at this time approached the apex of the projecting part of the follicle, and is discharged with the liquor folliculi, surrounded by the granular matter constituting the proligerous disc. If the Fal- lopian tube is applied to the ovary, the ovulum at once passes into the oviduct. At this step of the process, we may recognize the glandular structure and function of the ovary. When the peri- toneum and membranes of the ovisac are perforated, and thesug- Fig. 22. Fig. 21. Germinal Vesicle and Macula Ger- minativa. Ruptured Graafian follicle, with the escape of the Ovule. escent embrace of the ovarium by the Fallopian tube occurs, the channel from the uterus to the ovary is quite as unbroken as that 80 MENSTRUATION AND OVIPOSITION. from the bladder to the kidney. The ovisac is now the caecal ex- tremity of a glandular follicle, and the tube is its excretory duct. At this point the question occurs as to the mode in which the ovule is formed in the Graafian follicle. The earliest condition in which the follicles are seen in the embryo is in the shape of a spherical mass of cells, containing the germinal vesi- cle in its centre. From the external cellular mass is developed the membranes of the follicles, its epithelial lining, and the vitellary membrane. It is a question whether the germinal vesi- cle is formed or secreted by the cells forming the follicle, or whether its nucleus exists at the time the spherical arrangement of the cells takes place, the follicle being developed around the germinal vesicle and its nucleus. Some believe, with Huschke, that the ova are formed of acini, detached from the substance of the stroma of the ovary; others hold, with Dr. Martin Barry, that they are formed from the nuclei found in great numbers in the ovarian parenchyma. The latter seems most in accordance with the facts know respecting the origin of the ovary. Accord- ing to this view, the germinal vesicles and their nuclei exist from the earliest formation ofilthe ovary, and the follicle is devel- oped for the purpose of maturing and sustaining the ovule, and finally of extruding it from the ovarium when it has become fitted for impregnation. The comprehension of the mode in which the Fig 2"? ovule escapes periodically from the Graafian follicle, was arrived at quite as slowly, and occupied as many observers as the anatomy of the ovule Itself. Harvey drew a comparison between menstruation and the oviposition of birds. In 1672, Kerkrin- tiieFova£ of°a &ius advanced the idea that ova, at that time sup- newiy-bom child, posed to be identical with the follicles of De Graaf MembranUerelof were thrown off at the time of menstruation. The Foincie; 2, Epi- first positive observation of the rupture of a Graa- tbelium, or Mem- £ p iv i j • , • brana Granulosa; nan toilicle, during menstruation, appears to have minTvUlTs, b!en made by Sir Everard Home- Cruikshank, in vneiiary Mem- 1797, described the case of a woman who had died brane. during menstruation, and in whom the external membranes of the ovary were ruptured at one point. lie sup- posed that from this opening an ovum had escaped into the Fal- lopian tube. But these were isolated cases. The first body of OVA DISCHARGED AT MENSTRUATION. 81 facts bearing upon the matter was supplied by Dr. Robert Lee, whose first dissection was made in 1831. Dr. Power had, ten years previously, published his hypothesis respecting the period- ical escape of the ovule, at the catamenial periods. But, as we have seen, the discovery of the ovule, by Baer, was made in 1827. This discovery, which was not recognized by Dr. Lee, soon ren- dered the rupture of the Graafian follicle an intelligible fact, and the theory of Ovulation in the human female, and in the mammalia, has been completed by the researches of Pouchet, Negrier, Martin, Barry, Gendrin, Raciborski, Coste, Bischoff, and others. It may now, then, be considered as an established fact in physiology, that during menstruation, or the rut or heat of ani- mals, Graafian follicles are ruptured, and ova discharged. In the human female, it is believed that in ordinary cases the ovule escapes towards or shortly after, the termination of the men- strual flow, through the pore or fissure found in the peritoneal surface of the ovary. Sometimes an ovule escapes frem each ovary, or more than one ovule may escape from the ovary of either side. The observations of Dr. Ritchie and others have shown that ova, probably of immature formation, may escape before the time' of puberty, and occasionally Graafian follicles are ruptured in the intervals between the catamenial periods. In 6ome cases, the excitement of the ovary during menstruation may not be sufficient to cause the perforation of the follicle so as to admit of the escape of the ovule. The ovule has been detected in the Fallopian tube in persons who have died during or shortly after menstruation, by Dr. Letheby and by Hyrtl. The time occupied in the descent of the ovule through the Fal- lopian tube and uterus is not known precisely, and can only be inferred from the number of days after menstruation at which conception may take place. It is evident that several days must elapse before it escapes from the uterus. In the case of virgin or infertile ovulation, it is uncertain whether the ovule becomes decomposed or is discharged externally. Before the advent of puberty, the surface of the ovary is smooth, and the organ comparatively full and large ; but at each menstruation, one or more perforations occur, and the organ becomes, in process of time, scarred with numerous cicatrices ; so that, in the aged female, it is shrunk and corrugated with the remains of the 6 82 CAUSE OF THE COLOR OF THE CORPUS LUTEUM. numerous follicles which have been ruptured during the whole of the child-bearing epoch. Certain changes occur in the Graafian follicle, or ovisac, at, and subsequent to, the time of ovulation. These changes are more marked when impregnation has occurred, than in cases of virgin ovulation, and result in the formation of the Corpus iLutcum. At the time of the escape of the ovule, there is a greater afflux of blood than usual to the membranes of the ovisac, a clot of blood is effused into its cavity, and, according to the views of M. Pouchet, the epithelial lining, or membrana granu- losa, undergoes a remarkable development. This membrane be- comes thickened by a cell-formation, the hypertrophied cellular layer being at first of a reddish color, but afterwards becoming yellow. The yellow matter is arranged in the form of plicaB, which diverge from the cavity towards the circumference of the ovisac. The new formation is gradually thrown into folds, or corrugations, by the contraction of the ovisac, and becoming thicker as the development of the corpus luteum proceeds, its internal surfaces at length are brought into contact. In this way the stellate cicatrix found in the centre of the true corpus luteum is formed. Before this apposition has occurred, the fibrinous clot has been decolorized, or converted into fluid, and in either case absorbed. The substance of the corpus luteum is soft, fleshy, and friable, and is permeated with numerous vessels from the external surface of the ovisac, so that the true corpus luteum admits of being ejected from the vessels of the ovary. It should be said, that although little difference of opinion exists as to the appearances presented by the corpus luteum, numer- ous hypotheses have been advanced as to the mode in which the yellow layer, constituting its chief bulk, is formed. The latest evidence appears, however, to be in favor of its origin in the membrana granulosa. Dr. Lee contends that it is a deposit external to the lining membrane, and Mr. Wharton Jones joins him in his opinion. Knox, Miller, and Dr. Dalton regard it as a hypertrophy of the outer membrane, while Kolliker considers it to depend partly upon enlargement of the epithelial lining, and partly upon that of the internal or fibro-cellular layer of the ovisac. In size and shape the true corpus luteum, that which follows upon impregnation, resembles a small bean, and projects from CHARACTER OF THE CORPUS LUTEUM. 83 the surface of the ovary as a mamillary body, occupying from one quarter to one half of the entire superficies of the organ. It is largest in the early weeks of pregnancy, and after the third month it slowly decreases in size until the time of parturition, when it rapidly retrogrades, and at length becomes a mere scar. Its cavity is obliterated, at a variable time, being found in some Fid-24 Section of the Ovary, showing the Graafian Vesicle at the third month of gestation. cases after labour. It is at first filled with a clot, or serum, or the remains of the liquor folliculi, and the aperture through which the ovule has escaped sometimes remains pervious for a considerable time after impregnation. Fig. 25. a> h c Diagram of the formation of the Corpus Luteum in a Mammifer. a, The cavity of the follicle filled \rith blood; b, c, The clot diminishing in size, while the epithelial lining becomes thickened and convoluted; d, 6,f, Completion of the process. Upon the escape of an ovule from a Graafian follicle in the virgin, the changes described occur, but to a less extent than 81 DALTON's VIEWS OF THE COKI'US LUTEUM. when impregnation has taken place, and a false corpus luteum is formed. The membranous layer is less considerable, and in- stead of being of a yellow tint, is of a dull-red color. Accord- ing to Dr. Dalton of New York, who has carefully investigated this subject, it reaches its greatest development about three weeks after ovulation, and from this time rapidly disappears, leaving no vestige of its existence beyond a small scar. In the case of the virgin corpus luteum, other Graafian follicles are passing on to maturity, pari passu with its development, where- as in the true corpus luteum the occurrence of gestation suspends the maturation of ovules. As a general rule, the virgin corpus luteum is much smaller than the genuine formation, but cases occur in which the spurious equals the true corpus luteum in size. The differences between the corpora lutea of the virgin and of the impregnated female show that in the case of the lat- ter there is at the time of ovulation a greatly increased vascu- larity, and that during gestation the corpus luteum shares in the excitement incident to the gravid uterus. Other formations besides the corpora lutea of the nulliparous female have been mistaken for the true corpora lutea. Small tubercular masses are sometimes found having a certain resemblance to these bodies, and after the decline of the catamenia, the follicles which have not reached maturity during the era of child-bearing, collapse, and form cicatrices which have sometimes been thought to resemble the genuine corpora lutea. LECTURE V. MENSTRUATION. Gentlemen :—During the whole of the child-bearing era, women are the subjects of a sanguineous discharge every month, except during the times of pregnancy or lactation. The advent of this discharge is the chief external sign of the appearance of puberty, and it occurs in temperate latitudes at about the age of fifteen. In former times, the most exaggerated notions were entertained respecting the influence of climate in determining the early or late appearance of the catamenia. It was supposed that towards the arctic circle the catamenia occurred only in mature womanhood, and were then frequently represented by a colorless discharge, or only appeared during the summer months, while in the torrid zone, children of tender age became wive3 and mothers. These views have been corrected by modern re- searches, and especially by the investigations of Mr. Roberton, of Manchester. The results of his inquiries, and those of other observers, show that the difference between the date of the first appearance of the catamenia in the Hindoo female, in whom the influence of heat of climate is strongly marked, and the natives of this country, is about two years; the average age at the first menstruation being about thirteen in Hindostan, and fifteen in England. In Labrador a table of the first appearance of the menses has been obtained by Mr. Roberton, and the mean age, at the first menstruation, is nearly sixteen. Probably this vari- ation of three years between the Hindoo and the Esquimaux female is amongst the greatest that can be obtained, as the result of climatorial influence, in different parts of the world. A variation of three years in the time of the commencement of a function occurring between the ages of thirteen and sixteen, and lasting about thirty years, is, however, a very considerable one; and, while correcting old errors, we must be careful not to So 86 CLIMATE INFLUENCING PUBERTY. ignore the real effects of climate and temperature in hastening or retarding puberty. Dr. Tilt has made a very extended in- quiry into this subject, and the results of his tables show that there is an average difference of nearly three years between the date of the first menstruation in hot and cold climates. Perhaps if any criticism could be ventured upon respecting the valuable work of Mr. Roberton, and those writers who have adopted his views, it would be, that they have somewhat tended to make the influence of climate upon the functions of reproduction seem less than they undoubtedly are. It is found that other agencies, besides those of climate, affect the age at which menstruation commences. The catamenia appear earlier in the children of the rich than of the poor. The influence of a large manufacturing town like Manchester hastens the appearance of puberty. M. Brierre de Boismont ascertained that menstruation begins earlier in Paris than in the smaller towns of France, and in these again at an earlier age than in the wholly rural districts. Raciborski believes that race has an in- fluence upon puberty, apart from climate—as, for instance, that the English child, reared in India, menstruates at the time she would have menstruated in this country; but if a Hindoo child be brought to England, she will menstruate as early as though she had remained in Hindostan. It is also believed that Jew- ish females menstruate earlier in cold latitudes than the ordinary population. Probably climate, hygiene, temperament, and race all exert an influence in promoting or retarding puberty, but within a narrower range than was formerly supposed. Cases are met with occasionally of children menstruating, and having sexual feeling at a very early age ; but these must be considered as irregularities, having but little bearing on the function as ordinarily performed. The decline of menstruation, termed the change of life, or catamenial climacteric, generally occurs between the ages of forty-five or fifty, consequently the catamenial era spreads over from thirty to thirty-five years. The time of the decline varies in different individuals; sometimes it occurs as early as thirty- five, or even before that age; at others it lasts up to sixty or even beyond. Putting thirty years as the time during which a healthy female should have the menstrual periods, and suppos- ing them to occur every month, their number would be three MENTAL EFFECT OF MENSTRUATION. S7 hundred and ninety ; 30 x 13=390. But in married and child- bearing women, much of this time is occupied in gestation and lactation. During pregnancy, as the rule, the catamenia are absent, the cases in which a regular sanguineous discharge occurs during the whole of pregnancy being exceedingly rare. A discharge of blood for one or two periods after the occurrence of impregnation is more common. The great majority of women do not menstruate during lactation, but menstruation during suckling is by no means so unusual as the occurrence of this function in pregnancy. Many women habitually menstruate as regularly during lactation as at other times. It has been re- marked by many observers, that the intellect of women does not reach maturity until after the final cessation of the cata- menia; and it has been instanced as a sign of the superiority of the human race, that only a limited portion of the life of a female should be devoted to child-bearing. It is necessary to possess exact ideas respecting the times of the occurrence of a periodical function like that of menstruation. The catamenia, or menses, as the names imply, are said to return once a month in ordinary cases. Some authorities speak of solar, others of lunar months, as the period observed by the cat- amenia. Strictly speaking, the Solar month—that is, the time occupied in the passing of the sun through one of the signs of the zodiac—is nearly thirty days and a half. The Lunar month, or the time between one new moon and another, is twenty-nine days and a half. The Calendar month varies from twenty-eight to thirty-one da}rs. The catamenial month is dif- ferent from any of these, and consists of the common month of four weeks, or twenty-eight days, dating from the commence- ment of one period to the commencement of another. This is the ordinary periodicity observed by the catamenial function, or that which obtains in the great majority of women. Many females become unwell on the same day of the week for a long time, without any irregularity. In women who menstruate two or three days only, the interval between the cessation of one period and the beginning of another, is longer, and in those who are many days unwell, shorter; but the length or brevity of the discharge does not usually affect the time of its return. In some women, the monthly periodicity is so continuous and exact, that the times between successive pregnancies, if reduced 88 FREQUENCY OF MENSTRUATION. to days, are found to be multiples of twenty-eight. Cases are not uncommon, however, in which the catamenia return regu- larly at longer or shorter intervals than twenty-eight days, some women being unwell every six weeks, and others every two or three weeks, but there is generally a tendency to observe some multiple of a week. In some habits, a leucorrhceal discharge constantly occurs, and lasts for three or four days at the fort- nightly interval between the regular periods. Although there is a very general tendency to regularity in the performance of this function, it is very common to find occasional variations to the extent of a few days. Each " Period," as it is now common with educated women to call the monthly discharge, lasts usually in healthy women four or five days. Five days may be taken as the ordinary duration of the catamenial flow; but every woman has her con- stitutional peculiarity in this respect, some menstruating two or three days only, others always remaining unwell a week or more, such variations in women of different temperament and constitution being quite within the limits of health. The cata- menial fluid consists chiefly of the blood, modified to some ex- tent by the. ordinary secretions, and matters derived from the uterus and vagina. This is the result both of microscopical and chemical examination. The menstrual fluid has been examined with the microscope by MM. Donne, Pouchet, Dr. Ilassal, and others. It has been found to consist of blood globules and the fluid parts of the blood, with mucus from the glands of the cer- vix, cylinder epithelium, and granular matter from the cavity of the uterus, and scaly epithelium from the vagina. Dr. White- head has pointed out that the menstrual fluid as it escapes from the os uteri is alkaline, but that it becomes acid when mixed with the acid vaginal secretion, and this acidity, as formerly mentioned, tends to prevent its coagulation and decomposition in passing through the vagina. The menstrual fluid has been examined chemically by MM. Denis, Franz, Simon, Bouchar- dat, Rindskopf, and Dr. Letheby, and shown to consist chiefly of the elements of blood and mucus. An estimate of the amount of the discharge has been made by Dr. Meigs, who rates it at from four to six ounces at each period ; but this can only be approximative in the case of a loss which, like the number of days through which it continues, varies in different indi- CHARACTER OF THE MENSTRUAL DISCHARGE. 89 viduals. It was long supposed that menstrual differed from ordinary blood in the absence of fibrine in the former. It is now, however, understood that the cause of the non-coagulability of the catamenial fluid, and the apparent deficiency of fibrine, depend on the acid secretions of the vagina. [The importance of this physiological distinction in the char- acter of the menstrual secretion, was recently recognized in a legal aspect. During the recent coroner's inquest on the occa- sion of the Burdell murder, certain articles of male apparel were found to be bloody, thereby implicating certain individuals to whom they appertained. A scientific examination showed con- clusively that they were stained not with the blood of the mur- dered man, but with the menstrual non-coagulable blood, filled with epithelial scales, etc., of some one of the females of the house.] When contraction of the os uteri exists, and the menstrual blood does not escape readily, it coagulates in utero, and is ex- pelled with pain in the form of clots ; or, if the fluid is in quan- tity sufficient to neutralize the effects of the vaginal mucus, it coagulates after its escape externally. I use the terms " dis- charge" "loss" or flow," in preference to that of secretion, because the catamenia are essentially different from the products of any secretory process. The Influence of Menstruation, and the allied process of ovulation, upon the female economy is very great. The beauty of form incident to womanhood ; the marked characteristics of the female sex ; and the development of the affections, are in- timately connected with, and dependent upon, the healthy ap- pearance and performance of these periodical functions. The periods are commonly preceded by Irypogastric and lumbar un- easiness or pain, tumidity of the breasts, a dark appearance round the eyes, and a peculiar smell, especially adverted to by M. Pouchet, and which has been termed the vaccine odor. There is also in many women a tendency to relaxation of the bowels for a day or two before the discharge appears. Women are gene- rally more hysterical and irritable at this than other times. These symptoms are all relieved by the healthy catamenial flow ; personal loveliness is improved, and a new stimulus is imparted to all the organs of the body. The condition of the whole uterus is modified at the catame- 90 PHYSICAL EFFECTS OF MENSTRUATION. nial periods. The determination of blood to the organ renders it larger and darker in color than it is at other times. It is firmer to the touch, and lower in the vagina than usual. The Fallopian tubes partake of the turgescence, and have been ob- served almost black from engorgement. In ordinary cases, the canal of the cervix and the os uteri are somewhat dilated at, and for a few days subsequent to the menstrual date. This renders it easier to introduce the uterine sound just after the period than at any other time. In other cases there is a sphincteric con- traction of the os uteri, similar to tenesmus, which constitutes one of the forms of dysmenorrhcea. For a short time after the flow there is a marked increase of sexual feeling, and many wo- men in whom the aphrodisiac tendencies are moderate, state that they have little or no feeling at other times. The intention of this increased sexual sensibility, at the time when the ovule is ready for impregnation, and the uterus to receive the products of fecundation, is sufficiently evident. It is at this time also, in those whose feelings are intense, and unbridled by the higher qualities of the mind, that aberrations in regard to sex, and ten- dencies to nyphomaniacal excitement, occur. It is indeed diffi- cult to say in many cases of this kind, how much should be at- tributed to disease, and how much to moral delinquency. The Cause of Menstruation must be referred to the ovaria. These are the prerogative and ruling organs, a point insisted upon with great force and justice in the writings of MM. Pou- chet and Chereau in France, and Dr. Tilt in this country. It is found that in women with a proper development of the ova- ria, breasts, and external organs of generation, and in whom the sexual feeling is strong, but in whom the uterus is congenitally deficient, a monthly nidus occurs, consisting of pain in the back, and other symptoms which indicate that ovulation occurs regu- larly, although no sanguineous discharge takes place. In these distressing cases there is occasionally a show from the vulva or an attack of epistaxis, or bleeding from some other part, at the periods of ovarian excitement, but nothing like the menstrual flow. On the other hand, in cases where the ovaria have been extirpated, menstruation is effectually arrested, although the uterus remains perfect. This happened in a case in which Mr. Pott removed the ovaries in an operation on a patient at St. Bar- tholomew's Hospital. Dr. Frederick Bird has also informed me COMPARATIVE PHYSIOLOGY OF MENSTRUATION. 91 that in a case in which he removed both ovaria, in double ova- rian disease, and where the patient recovered, permanent ame- norrhcea was the result. We may look, then, to the ovaria for the exciting cause of menstruation, and this function is evidently subsidiary to that of ovulation. Symptoms in some degree analogous to those of menstruation occur in the lower animals at the dates of ovulation. A com- parison has been made between the menstruation and the deter- mination of blood to the comb of the domestic hen, the genitals of the pigeon, and birds of the parrot tribe. In many of the lower mammalia, discharges from the genitalia take place at the time of the rut or heat, during or immediately after the occur- rence of ovulation. In some of the quadrumana, sanguineous discharges have been observed; and it is believed that in the monkeys the oestrum has a monthly periodicity. Dr. Hille, a Dutch physician of Surinam, possessed a female monkey, which was the subject of a sanguineous discharge, lasting three or four days, every month. In others, as the Macacus libidinosus, the callosities near the anus, and the whole of the parts below the tail, become periodically of an intensely vivid red color, and present an appearance, to use the words of M. Coste, of an im- mense phymosis. The phenomena of oestruation are more marked in wild than in domesticated animals, and in those which only cestruate once a year, the date of oestruation occurs at such a time as to admit of the completion of gestation and parturition in the spring season. Little is known of the gesta- tion of the quadrumana; but in the lower mammalia, the changes which occur in the lining membrane of the uterus could not well be the same as those belonging to the human fe- male, because in the lower animals that which answers to the decidua of the human female is a permanent organ. Divers opinions have been held respecting the exact Source of tne Menstrual Flow. It has been referred to the ovaria, the Fallopian tubes, the cavity of the body of the uterus, the os and cervix uteri, and the vagina. Yery recently, M. Ch. Judee has published the result of three autopsies of women who died near the menstrual period, in which he states that the mucous surface of the os was abraded, and he considers this a proof that the menstrual blood comes from the lips of the os uteri. I have no doubt these were really cases of abrasion, or ulceration, of 92 SOURCE OF THE MENSTRUAL FLOW. the os uteri, and in such cases there is at the menstrual period a discharge of blood from the diseased surface, as well as from the interior of the uterus. In such cases the os uteri becomes, for a time, a menstrual ulcer, and the secretion of pus is converted into a discharge of blood. All the exact evidence we possess points, however, to the cavity of the body of the uterus as the true seat of menstruation, and source of the discharge. The catamenia may often be seen escaping from the os uteri, in ex- aminations with the speculum. In cases of procidentia the whole process may be watched, and in these cases the fluid always comes from within the uterus. In cases of inversion, we have a still more positive proof, as the blood may be seen exu- ding from the surface of the inverted organ. The commence- ment of the flow at each period takes place very gradually. In examining patients, I have sometimes seen the first trace of the sanguineous discharge at the os uteri, but it has been twelve hours or more before it has appeared externally. The quautity of discharge being at first small, it passes down the vagina very slowly. Probably the period ceases in the same gradual man- ner, atid has disappeared from the os uteri some time before the discharge is lost at the ostium vaginae. Within the last two years I have had opportunities of examin- ing three uteri taken from women who had died during the cata- menial flow. In each of them I found the mucous membrane of the body of the uterus either in. a state of dissolution or entirely want- ing. In one case, that of a woman previously in good health, who died suddenly from a fit of apoplexy while menstruating, and whose uterus was kindly sent to me by Mr. Filliter, of the Maryle- bone Infirmary, the mucous membrane was altogether gone. At the upper part of the cervix uteri the break in the mucous mem- brane was very apparent. In the cervical canal the mucous membrane was perfect; but at the os uteri internum, it ceased as abruptly as though it had been dissected away with a knife above this point. Blood was oozing at numerous points from broken vessels in the sub-mucous tissue. I had the assistance of Dr. Handfield Jones in examining this uterus with the micro- scope, and we could find no traces of the epithelium or of the utricular glands. The surface of the cavity of the body of the uterus was exactly similar to that which may be seen after abor- tions, in which the decidua, or in other words the developed APPEARANCES OF UTERINE TISSUES. 06 mucous membrane, has been discharged. The sub-mucous sur- face was a pulpy mass, in which epithelium, the ends of vessels, Fiat 2S. Uterus of a woman who died from apoplexy during the catamenial flow. The whole of the mucous membrane of the body of the uterus is wanting. broken tubes, blood globules, and mucous corpuscles were all that could be distinguished. I compared this uterus with that of a woman who had died after an abortion at the third month, and the appearances in the two cases were precisely similar. [March 11th, 1857. I saw the nulliparous uterus of a young murdered woman, death occurring from loss of blood, exhibited by Dr. Finnell to the New York Pathological Society. This and every organ, was blanched in the extreme. One ovary exhibited the corpus luteum of a menstruation some four weeks ante- riorly, containing a clot not yet entirely changed in color. The other ovary showed the Graafian follicle almost ready to burst, the peritoneum over it thin and highly injected. The os uteri was in a perfectly natural condition and with no flow from it or exudation from its lips. On laying open the uterus, the mucous membrane of the body was found highly injected and covered with a glairy, bloody effusion. The cavity of the neck, however, contained not a drop of fluid and did not seem to be 94 POST-MORTEM EVIDENCES OF MENSTRUATION. in the least injected. It showed, in short, the uterus prepared for menstruation, which had not however occurred.] The State of the uterine mucous membrane during men- struation has occupied many observers. It has generally been described as thicker and more swollen during the catamenia than at other times. It should be mentioned, however, that descrip- tions of the uterus a few days before or after the menstrual flow can have little bearing upon this subject, and it is a rare occur- rence to get the uterus of a woman who has died in the middle of healthy menstruation. No safe conclusions can be drawn from the cases in which women suffering from severe dis- ease have a sanguineous discharge from the uterus at the time of death. Professor Simpson, in 1846, in his paper on the ex- pulsion of the entire mucous membrane in certain cases of dys- menorrhcea, drew a comparison between ordinary menstruation and the process of digestion, in which the epithelial layer is shed and removed after every meal. M. Pouchet has supposed that a decidual membrane is formed during each catamenial period, and discharged in the shape of an albuminous plug ten or twelve days after the cessation of the flow. . Kolliker states that the mucous membrane becomes thickened during menstruation, the blood escaping from the ruptured superficial capillaries and that the epithelium of the cavity of the body is in great part thrown off; but he considers it as abnormal if the whole or part of the entire mucous membrane should be detached. Muller compares the change in the mucous membrane of the uterus during menstruation to moulting, attended, perhaps, by the for- mation of a new epithelium. A case recorded by Dr. Janser has been often quoted. It was that of a girl murdered four days after menstruation. He describes the mucous membrane as somewhat thickened, and easily lifted from the surface by the handle of the scalpel. It was composed of the utricular glands, arranged perpendicularly, side by side, and covered by cylinder epithelium. This observer concludes that during menstruation the mucous membrane of the uterus presents the same charac- ters as in the early part of gestation. Such cases, however, really prove nothing with respect to the condition of the mucous membrane during the actual presence of menstruation. In an organ like the uterus, the most important changes may occur in the space of four or five days. * PECULIAR VIEWS OF MENSTRUATION. 95 It appears to me to be in accordance with what I have observed in uteri examined during the menstrual period, the facts connected with membranous dysmenorrhoea, and the detachment of the decidua in abortion and parturition, to sup- pose that the mucous membrane is in great part or entirely broken up, and its debris discharged during each menstruation. The blood is probably exuded during the breaking up of the mucous structure, and the duration of the menstrual period represents the time occupied in this periodical decadence and renewal of the mucous membrane of the body of the uterus. In cases of Membranous Dysmenorrhea we have proof of the exfoliation of the mucous membrane in an entire form, or in detached pieces. This may occur every month for many years, a new mucous membrane being developed after each men- struation. After abortions and after parturition we know that the old mucous membrane is thrown off, and a new one formed. According to the view I have stated, a new mucous mem- brane is formed every month as part of the process of pre- paration for the reception of a fecundated ovum ; not that the aptitude for the reception and implantation of the ovum is lim- ited to the newly-formed mucous membrane, though it is pro- bably greater at this time than at others. The mucous mem- brane may become the seat of the changes consequent upon impregnation just before a menstrual period, and in cases where menstruation is suspended. According to my view, the mucous membrane of the uterus becomes excrementitious every month, and is discharged from the cavity of the uterus in a state of disintegration, and the uterus forms a new mucous coat, by a process similiar to the reproduction of lost parts. Such a doctrine may at first sight appear startling, but we have always had a similiar condition, during the menstrual period, under our eyes, in cases of vicarious menstruation. In these cases, an ulcer upon any part of the surface of the body may skin over, or assume healthy granulations, during the inter- vals of menstruation, but on the occurrence of the period, the newly formed skin gives way, or the healthy granulations slough, and blood exudes from the surface for several days; after which the ulcer heals, or puts on a healthy aspect, until the approach of the next catamenial period. I have at the present time a patient with a menstrual ulcer upon the dorsum of the tongue, 96 VICARIOUS MENSTRUATION. in whom the sore heals partially or entirely between the periods, but at the catamenial dates the surface gives way, the sore becoming deepened, and exuding blood, while the catamenia are flowing. We have only to consider similiar phenomena as occurring to the mucous membrane of the body of the uterus, and we have a reasonable explanation of the mode in which this peculiar function is performed. [ It may be well to state distinctly that these views are far from being generally accepted by the scientific, and the student should read them cumgratio sails. A forthcoming work by an American of great distinction, who I am not at liberty to men- tion, will probably throw some new light upon this questio vcx- ata as well as upon that of foetal circulation.] LECTURE VI. CONCEPTION, AND THE EARLY DEVELOPMENT OF THE OVUM. In a former lecture we traced the anatomy of the Ovule up to the point of emission from the ovarium, considering it chiefly with reference to ovulation and menstruation in the unimpreg- nated state. It now becomes necessary to study it in relation to the act of fecundation, and the early changes which occur in the impregnated condition. As the ovule approaches maturity, and makes its exit from the Graafian follicle, a remarkable change occurs in the germinal vesicle. It is believed by almost all observers, either to disappear or to become entirely transformed. Dr. Martin Barry asserts that it does not disappear, but returns again to the centre of the ovule, where it becomes changed by a process of cell-development, and ends in producing two cells in the centre of the yelk, from which cells the embryo is after- wards developed. It appears from the latter researches of Mr. Newport, that there is a partial return of the germinal vesicle towards the centre of the yelk, and that considering the germinal vesicle as a parent cell, its nuclear particles, which form the ger- minal spot, are developed into secondary cells; these again into cells of tertiary formation, and so on, until the germinal vesicle has been transformed into a mass of cells, which leads to the rupture and diffluence of the parent cell, or germinal vesicle. From some one of these cells it is believed that a larger cell, the future Embryo-cell occupying the site of the macula germina- tiva, and constituting the true Germinal Point of the future being, is developed. It is, however, as yet uncertain whether the embryo-cell, or vesicle, which replaces the germinal vesicle, is formed just before or just after, the act of fecundation. It is necessary in this place to glance briefly at the male element of impregnation. The part of the seminal fluid actually H 97 98 MALE ELEMENTS FOR FECUNDATION. required for conception is the Spermatozoa. For a long time the spermatozoa were thought to be distinct animalcules, but they are now known to be particles, sui generis, developed within the seminal cells found in the secretion of the testis before it leaves the gland. While they remain within the cells, these filaments are arranged in bundles, but in the passage of the fluid from the gland through the efferent apparatus, the cells rupture and set free the spermatozoa. Each spermatozoon con- sists of an oval and flattened body, and a filamentous portion, or tail. The width of the body is about goVo Part of an inch, and the length of the entire particle is from T^ to g^o °f an inch. Kolliker believes the spermatozoa to be allied to ciliated cells, and they move in the fluid semen or traverse the mucous membrane of the genital passages, by a succession of smart lash- ing movements. It has been proved by direct experiments, such as filtering the semen, and using the spermatozoa, and the pure liquor seminis, the impregnation of the ova of amphibia, that it is the spermatic particles and not the liquor seminis which are the real agents of fecundation. Thus, then, on the part of the female, we have the ovule pro- duced in the ovarium, the essential part of which is the germi- nal vesicle or germ cell. On the part of the male, we have the spermatic fluid, the essential part of which is the seminal vesicle, or sperm cell, produced in the testis. The bundle of spermatic particles, or spermatozoa, formed in the germ cell, correspond Fig. 27. a,o, Sperm cells, containing nuclei, each nucleus having within it a spermatic filament, o, A nucleus with nucleoli, d, Nucleus, with spermatic filament, e, A cell, with a bundle of sper- matic filaments, f, g, h, Spermatic filaments. with the nuclear particles forming the macula germinativa, or germinal spot, of the germ cell. The spermatozoa may be con- » PHYSIOLOGY OF FECUNDATION. 99 sidered, in fact, as the nuclear particles of the germ cell. The bursting of the sperm cell and formation of the spermatozoa, on the one hand, and the development of the nuclear particles of the germ cell into the cellular mass which occupies the place of the germinal vesicle after its rupture, is the highest point of development to which the male and female elements can reach, if fecundation does not occur. It will be observed that several generations of cells have followed upon the germinal vesicle and its nucleus, before the ovule has been rendered ripe for impreg- nation ; and the spermatozoa are also the secondary or tertiary products of the cells found in the secretion of the testis. We now approach the act of Fecundation or Impregna- tion, and recent researches have gone far to solve this, one of the most mysterious processes in the arcana of Nature. In the fecundation of the vegetable ovum, it has long been known that the moving spermatic particles of the pollen cell penetrate the ovum, and unite with the contents of the ge-rm cell. Prevost and Dumas believed that the spermatozoa penetrated the ovum bodily, and became metamorphosed into parts of the future embryo. In 1843, Dr. Martin Barry published, in the " Philo- sophical Transactions," an account of the actual penetration of the ovum of the rabbit by the spermatozoa, and he demon- strated the fact to the satisfaction of Dr. Sharpey, Mr. Owen, and Mr. Grainger. He believed that the spermatozoa pene- trated the yolk, and there became divided into many parts. The following figure from Dr. Barry's paper represents the sperma- tozoa after they have entered the ovum : An ovum of the rabbit, taken from the Fallopian tube, twenty-four hours after leaving the ovary. 1. Zona pellucida. 2. The germ, consisting of two large cells. Several smaller cells, and numer- uos spermatozoa, are visible. * 100 PHYSIOLOGY OF IMPREGNATION. This view of Dr. Martin Barry was combated by many obser- vers, particularly by Bischoff. Mr. Newport, in his first investi- gations into the impregnation of the ovule of the frog, published in 1851, did not agree with Dr. Barry. He believed that the moving spermatozoa approached the ovule, became applied to the surface, and disappeared in that situation by a process of diffluence or disintegration. He subsequently modified this opinion, and became convinced that the spermatic particles are imbedded in the walls of the ovule and perforate the vitellary membrane in large numbers. Keber discovered that in the fresh-water muscle the spermatozoa pass into the interior of the ovum by a canal or opening in the walls of the ovum. The researches of Keber have been verified by Dr. Martin Barry and Dr. Webb, of Lowestoft, and confirmed by Meissner and others. Miiller has described a funnel-shaped, canal in the ova of every species of Holothuria, having probably the same func- tion. Lastly, Dr. Nelson has investigated the reproduction of the Ascaris Mystax, an entozoon found in the intestine of the cat, and demonstrated the penetration of the ovule by the spermatic particles in the clearest manner. These observations of Dr. Nel- son have also the high authority of Dr. Allen Thompson in their favor. It may be considered, then, as proved that the spermatozoa penetrate the ovum, and come into positive con- tact with the contents of the germ cell. Impregnation does not, however, depend on the penetration of the ovule by one sper- matozoon, but by considerable numbers of spermatozoa. Mr. Newport found that the greater the number of spermatozoa in apposition with an ovule the more certain its fecundation became. Dr. Nelson observed that in the ascaris mystax a suffi- cient number penetrated the chorion and vitellary membrane, to form a ring around the germinal vesicle. It is not by the influence of particle upon particle, but of mass upon mass, that the phenomena of impregnation are accomplished. After the pen- etration of the ovule, the spermatozoa lose their motor power, become disintegrated or dissolved, and disappear ; not, however, until they have communicated to the ovum, that wonderful force which leads to the formation of a future being, but without which the ovule dies like any other simple animal cell. The ovule having thus been converted into the Ovum by the process of fecundation, we have now to speak of the earliest GERM-MASS. 101 phenomena observed in the development of the new organiza- tion. The first change which is known to occur is the cleavage or segmentation of the yelk. The embryo cell first elongates, then becomes violin-shaped, and afterwards separates into two cells by spontaneous fission—an observation first made by Swam- merdam. With this division of the embryo cell the yelk divides into two masses, and the two cells are now in the cen- tres of the two portions of the yelk. By a similar process, the two cells divide into four, and these again into eight, and so on, the yelk combining with the individual cells, until the process of segmentation is completed, and the product of the embryo cell and the yelk form together a homogeneous mass of cells, termed from its endowments the Germ-mass, and which, from the appearance it presents, has been called by some authors the mulberry mass. In the formation of the germ-mass, the cells have evidently multiplied by the assimilation and conversion of the yelk. This germ-mass is the plastic material out of which the whole organization of the foetus is gradually evolved. Fie, 29. A Ovum, with the first embryo cell. B, Division of embryo cell, and cleavage of the yelk round it. C, Second division, and segmentation. D, Farther division. E, Germ-mass or Blastoderm forming. Professor Owen is of opinion that not all these germinal cells are consumed in the formation of the individual fabric, but that, in the mammalia, for instance, a certain portion is reserved, and that this reserve becomes the ovarium or testis of the future animal. In the amphibia, and still lower in the scale, the remnants of the germinal cells not only go to form the sexual organs, but are 102 MICROSCOPICAL ANATOMY OF THE EARLY OVUM. located in different parts of the body, and become the agents in the reproduction of lost limbs or organs. This philosophical view of Mr. Owen is combated by Dr. Allen Thompson, one of the ablest embryologists in this country, on the ground that at an early period of development no difference can be seen between the blastema or commencing structure of the ovaria or testes and any other organ. Still the opinion of Mr. Owen upon this point cannot but carry great weight. It is probable that the blastema of all organs contain, in the first instance, germinal cells, which are gradually exhausted in the development of the tissues, but which in the ovaria and testes are reserved for the evolution of new individuals. If we believed, with Mr. Owen, that in each female a part of the residual germ-mass goes to the formation of the ovaria, and the evolution of germs in a new generation, wre might infer that the human race is still in its infancy. The changes in these germ-cells, occurring but once in every generation, if multiplied by the generations of men which have lived upon the earth, are infinitely less in number than the changes which occur in particular cells in the lifetime of an individual. The epithelial cells of the digestive tube may be cited as an example, in which new progenies of cells are produced and destroyed after every ingestion of food. After the formation of the germ-mass by the process of seg- mentation, those cells which are nearest the surface, and imme- diately under the zona pellucida or vitellary membrane, become aggregated together at one part of the ovum, so as to form a layer, which constitutes the blastoderm, or Germinal Mem- brane. This membrane, in the first instance, divides into two layers—the external or Serous Layer, and the internal or Mucous Layer, for a knowledge of which we are indebted to Pander, of Wurzburg. Subsequently, other cells of the germ-mass collect between the serous and mucous layers, and arrange themselves into a third layer, which is termed the Vascular Layer. The serous layer gives origin to the vertebral column, the brain and spinal marrow, the extremities, and the general skeleton. In the mucous layer arise the mucous structures and the glands; while in the vascular layer, the heart and vascular system origi- nate. In forming a proper idea of these layers, the student must bear in mind that they are not flat layers, but are three spheri- cal membranes contained within the external membrane of the ZONA PELLUCIDA. 103 ovum—that is, the vitellary membrane, or zona pellucida. On one aspect of the sphere, these membranes become thickened by the accumulation of cells, and in this thickened portion of the membrane the rudiments of the foetus are formed. Attention must now be given to this thickened part of the several layers, and the student should consider himself as looking at a circnm- 3cribed portion of their spherical surfaces. The dense area re- ferred to constitutes the Area Germinativa, which is first round, then oval, and subsequently pyriform in shape. In the centre of the area germinativa, the cells of the serous and mucous layers become fewer in number, so as to render them comparatively transparent, thus forming a space called the Area Pellucida. Around this pellucid space a boundary is formed by an accumu- lation of cells in the vascular layer, and this circle is called the Area Vasculosa. In the centre of the area pellucida, and in the "Ptts. 30. Diagram of Area Germinativa. In the centre, the Primitive Trace. Immediately surrounding it is the Area Pellucida, bounded by the dark Area Vasculosa. serous lamina, the first sign of the foetus appears in the form of a transparent groove. This groove, which is the Primitive Trace, is surrounded by two elevated ridges, called the Laminae Dorsales. The primitive trace may be said to represent the future cerebro-spinal nervous centres, the dorsal laminae, the cranium, and vertebral column. The ridges or elevations of the serous layer, constituting the laminEB dorsales, approach each other, as the process of development goes on, and unite above, in this way closing over the groove already described. Thus the vertebral canal is formed by the fusion of two processes of the 104 DEVELOPMENT OF THE OVUM. serous layer at their apices. This method of forming separate cavities, from the layers out of which the foetus originates, deserves attention, as it is repeated again and again as the devel- opment of the ovum proceeds. Fia. 31. 1 || j ---M 1, Area Pellucida, 2, Lamina dorsales. 8, Primitive trace or groove, Pig* 32. 1, 2, 8, Commencement of Cerebrum, Cerebellum, and Spinal marrow. 4, Commencement of Vertebral column. While the upper portions of the dorsal laminae are thus clos- ing over to form the vertebral canal, the under portions,-which •constitute the Laminae Ventales of Baer, elongate to form the ribs and abdominal walls, and they have the same tendency to meet and unite in the medial line. In this way the abdominal and thoracic cavities are formed, and the mesial raphe indicates in after life the place of union. Thus the vertebral and cranial cavities, and the cavities of the thorax, abdomen and pelvis, all lined with serous membranes, are inclosures separated off from the general cavity of the primordial serous layer of the ovum. The limbs with the joints and their fibro-serous linings are also derived from the same membrane, and possibly their sympathies in disease with the larger fibro-serous membrane, as in articular rheumatism and pericarditis, may be referred to their common origin. It is easy to understand, that if the closing in of the CAUSE OF VARIOUS MONSTROSITIES. 105 spinal canal by the laminae dorsales should be incomplete, we have spina bifida or hernia cerebri as the result; or that, if the lower laminae do not meet in the median line, we have cleft palate, hare-lip, deficiency in the walls of the thorax and abdo- men, and other malformations depending on insufficient develop- ment at this early period. At this epoch of development it is, that various monstrosities, arising out of the union of twin foe- tuses, occur. If two impregnated ova join anteriorly, before the closing in of the abdominal and thoracic cavities, or posteriorly before the arching in of the vertebral and cranial canals, we may have an abdominal or spinal canal common to both. It is upon this principle, applied to the serous, vascular, and mucous layers, that all the varieties of double monster are to be explained. In the case of the African twin, recently exhibited in this country, the junction was at the sacral bones, and the ova must have united together at the sacrum, before the arching in of the sacral por- tion of the vertebral canals, so that the posterior aspects of the two sacral bones became fused together, the vertebral columns being separated on every other point. In the vascular layer, and in that part of it which has been referred to as the area vasculosa, surrounding the area pellucida, the first blood channels are formed, by the unions of files of cells, and the obliteration of the cell-walls at the points of union; the first blood discs being formed, according to Dr. Carpenter, from the nuclei of the cells which have united to form the ves- sels. These vessels increase and enlarge, and are destined at first to carry to the embryo the nutriment absorbed from the yelk and from the chorion, the formation of which will hereafter be adverted to. The heart is formed in the same manner as the first bloodvessels, from cells, and retains for some time its cellu- lar character. The vessels are, however, first formed, and the flow of the earliest blood globules is not from, but towards, the Punctum Saliens, or commencing heart. From this beginning the circulating apparatus is gradually developed, passing through the phases which are permanent in fishes and amphibia, to reach at the time of birth, the mammalian type. Early in the formation of the embryo, the Amnion, the envel- ope belonging essentially to the ovum, begins to appear. It is formed in the following manner : Beyond the two extremities of the ovum, and on the outside of the area pellucida, the serous 106 WHAT IS MAN ? lamina projects in the form of two hollow processes, which gradu- ally arch over the whole of the foetus, so that the dorsal aspect of the embryo is entirely covered by two layers of the series lamina. These processes meet in the centre, and unite together. At first the processes are, at their origin, separated to a consid- erable extant on the ventral surface of the embryo, but they gradually approach each other at the umbilicus, and ultimately surround the elements forming the umbilical cord. Of the two layers of which the amnion is formed, one surrounds the embryo, and constitutes its proper envelope ; the other becomes adherent to the external or maternal membranes. The cavity of the amnion becomes filled with a watery secretion^ and the embryo is thus suspended in a fluid medium, which affords many advan- tages during the progress of utero-gestation. From the time when the amnion is first formed to the date of parturition, this mem- brane and the bulk of the fluid it contains continues to increase. The outward pressure of the amniotic fluid seems to be the chief agent in promoting the extension of the external membranes of the ovum. It is worthyr of remark that the secretion of a large quantity of fluid by a serous membrane, which secretion is closely allied to the dropsies of the serous cavities, should in the ovum be a purely physiological process. Sometimes the amni- otic fluid is in excess, when we have what is termed dropsy of the amnion. It will not be forgotten that the amnion, like the serous lining of the vertebral and cranial cavities, and the serous membranes of the chest and abdomen, are developed from the serous layer of the early ovum, and these membranes, like the amnion, have in the foetal state a tendency to excessive secre- tion, leading to congenital hydrocephalus and ascites. We may perhaps find an explanation of the sympathies between the skin and the serous membranes, as in the production of peritonitis or pleuritis, by the influence of cold upon the skin, in their com- mon origin from the serous or cutaneous layer of the ovum. The amnion is a reflexion from that part of the layer which forms the skin, and at birth the skin and amnion are continuous at the umbilicus, the amnion being reflected on the umbilical cord so as to form its external covering. The subject of the evolution of the perfect individual from a triple membranous sac would admit of an extensive development in human physiology and pathology. Man in his greatest pride does but consist of FORMATION OF THE UMBILICAL VESICLE. 107 the involutions and devolutions of these membranes. Upon the vital energy possessed by these layers depends his health, his ten- dencies to the diseases of the systems evolved from them, and the duration of his existence. Fig. 33. Fia. 34. Fig. 33.—Diagram of early Ovum. 1, Serous lamina. 2, The yelk. 8, Embryo. Fig. 84.—Diagram showing the commencement of the Amnion. 1, Chorion. 2, Yelk sac. The folds of serous membrane are rising at two extremities of the embryo, to form the amnion. The mucous layer has been described as the most internal of the membranous layers within the vitellary membrane. It is therefore in immediate contact with the central portion of the yelk, or that part of the mulberry mass not used up in the for- mation of the three primary layers themselves. The first com- mencement of the mucous canals is made by a constriction of the mucous layer on the under surface of the commencing foetus. The constriction is formed by two processes of the mucous layer, which gradually approach each other. This constriction increases, until the smaller mucous cavity, from which the mucous membranes and glands are developed by a process of reduplication, is nearly cut of from the larger mucous cavity, containing the remains of the germ-cells. This larger cavity it is which constitutes the Umbilical Vesicle, and the point of division between the two cavities is subsequently the umbilicus. It is from the umbilical vesicle that the embryo at this early period derives the greater part of its nutriment. At this time, the umbilical vesicle is continuous with the abdominal mucous cavity, by means of the vitelline duct at the umbilicus, the material of the yelk is conveyed to the embryo, not only by the duct, but by means of vessels developed in the part of the muc- ous layer composing the walls of the umbilical vesicle, and which vessels are called the vasa-omphalo-meseraica. The omphalo- 108 OFFICE OF THE ALLANTOIS. meseraic vessels consist of an artery and vein, which extend from the umbilical vesicle to the superior mesenteric artery and vein, in which they terminate. This state of things continues until the whole material of the yelk process has been converted to the uses of the embryo, when the umbilical vesicle, with the omphalo-mesenteric vessels, shrinks up, and their remains con- stitute the Vesicula Alba, the white spot frequently seen, with great distinctness, in the abortion of early ova. Fig. 35. 1, The Chorion. 2, Yelk mass and commencing Umbilical Vesicle. 3, Embryo. 4, 5, 6, Folds of serous layer forming Amnion. 7, Commencement of Allantois. The Allantois is another temporary structure which, with its mode of origin, it is necessary to describe. It is formed at the lower and anterior part of the embryo, not apparently from any reduplication of either of the primary layers, but from a mass of cells, in the same way as the heart and bloodvesels are formed. The cellular cavity is at first elongated in shape, but by the usual process of constriction it becomes divided into two, a larger and a smaller portion, communicating with each other, and of which the smaller is the urinary bladder. The uraclms, the cord leading from the bladder to the umbilicus, is the remains of the duct which originally connected the bladder and the allantois. The allantois is partly intended as an excrementi- tious organ, receiving the earliest secretion of the kidneys, but chiefly, in the mammiferous ovum, as a means of conveying a loop of the bloodvessels of the embryo to the maternal surface of the ovum, and thus providing the permanent foetal provision for nutri- tion and excrementation. This will be again adverted to when describing the maternal portions of the membranes of the ovum. LECTURE VII. THE DECIDUA, CHORION, PLACENTA, AND UMBILICAL CORD. Gentlemen :—While the changes which have been described in the previous Lecture as the results of fecundation, are pro- ceeding in the embryo, other phenomena, equally necessary to the development of the ovum, are occurring in the uterus. The for- mation of the Amnion on the part of the embryo has been already referred to, and there remain for consideration two other mem- branes, the Decidua and the Cliorion, both of which are formed on the side of the mother; and the Placenta, which is devel- oped from the bloodvessels of the foetus, and from certain por- tions of the chorion, and decidua. The clearest information respecting these structures will probably be conveyed by an account of the mode in which they are developed. On the occurrence of impregnation, a remarkable stimulus is imparted to the uterus, before the ovum has entered this organ, and certain changes are produced which fit it for the reception and retention of the embryo. The Membrana Decidua, so called from its destruction at the time of parturition, is entirely the production of the uterus, and has been the subject of many discussions since the time of its first accurate description by William Hunter. In the early part of pregnancy, the decidua consists of two principal portions, the Decidua Vera, lining the cavity of the uterus, and the Decidua Reflexa, which immedi- ately surrounds the embryo. At this time, owing to the small size of the ovum, as compared with the cavity of the uterus, these two portions are in contact only at the point where the ovum rest upon the uterus, this being generally at the upper part of cavity of the fundus, near the opening of one of the Fallopian tubes. Up to a comparatively recent period, the opinion which chiefly prevailed respecting the formation of the decidua was, that, immediately after fecundation, the uterus developed upon 109 110 VIEWS RESPECTING THE DECIDUA. its internal surface a membranous sac, constituting4he decidua vera, and that the ovum, descending the Fallopian tube, entered the uterus by pushing before it a reflexion of this new mem- brane. It was supposed that the fold originating in this way, enveloped the embryo, and constituted the decidua reflexa. The ovum thus appeared to become involved in a duplicate membrane, which has often been compared to the double envel- ope of the heart formed by the reflexion of the pericardium. Dr. Sharpey was first to call into question the common belief respecting the nature and formation of the decidua, and his investigations led him to the conclusion that the decidua vera was not a membrane formed upon the-uterine mucous surface, but that it consisted of the actual mucous membrane of the uterus itself, altered by a process of development, under the stimulus of impregnation. Dr. Sharpey was followed by E. II. Weber and others, whose researches have all tended to con- firm this view; and we now possess a large body of facts, which appear satisfactorily to explain the origin of the decidua vera and reflexa, and the relation of the decidua to the chorion and to the formation of the placenta. The earliest changes which occur in the cavity of the uterus, after the impregnation of the ovule, consist of a swelling of the tubular glands of the mucous membrane, and of the capillary vessels distributed in the interspaces between these glands. In the uterus examined a short time after the occurrence of fecun- dation, the glands are distinctly visible to the naked eye. Their length at this time is from one and a half to two Paris lines. The tubes beccme lined with epithelium of a whitish color, and a profuse secretion of celloid particles and albuminous mat- ter takes place from the surface of the mucous membrane in the inter-follicular spaces. This cellular secretion is so profuse that it not only forms a layer upon the surface, but a considerable quantity is poured into the cavity of the uterus. The enlargement of the tubular glands already referred to, and of the capillaries of the intergland- ular spaces, together with the plastic secretion poured out upon them—in other words, the altered mucous membrane of the uterus—constitute the decidua vera. With respect to the mode in which the decidua reflexa is formed, the latest views are those of Professor Goodsir and M; Coste. Mr. Goodsir, in his GOODSIR's VIEWS OF THE DECIDUA. Ill paper " On the Structure of the Human Placenta," published in 1845, explained the formation of the decidua in the following Fro. 36. Fl&. 37. Fig. 30. Section of the lining membrane of the uterus at the beginning of pregnancy, twice the natural size. 1, opening of the glands on the surface of the cavity; 2, The utricular glands. Fig. 87. A portion of glandular structure twice magnified. 1,1, Orifices of the glands; 4, Cae- cal extremities of glands; 5, Tubular portion of glands. manner. He considered the celloid matter secreted from the uterine follicles and the inter-follicular spaces, to belong to what he terms the third order of secretions—that is, the cells have the power of accomplishing further changes, and of developing other cells from their nuclei, after they have left the mucous membrane which originally produced them. The small ovum, on entering the uterus, becomes, according to Mr. Goodsir, imbedded in the cellular matter of the cavity of the uterus, which combines with its outer envelope, the chorion, hereafter to be described, and ultimately forms the decidua reflexa. The decidua vera, then—in the opinion of Mr. Goodsir—consists of the uterine mucous membrane, altered in the manner de- scribed ; while the decidua reflexa is a membranous, or plastic, structure formed out of the cellular secretion derived from the mucous surface, or decidua vera. According to the views of 112 COSTE'S VIEWS OF THE DECIDUA. M. Coste, published two years later, the decidua vera and decidua reflexa, are both produced by the metamorphosis of the mucous membrane of the uterus itself. He believes that the ovum, on entering the uterus, is embedded in the soft and tur- gid mucous membrane, which becomes specially increased in thickness at the point which receives the ovum, and rising around it like the florid granulations of an issue around a pea ultimately meets, and is united, so as entirely to surround the ovum. The view of M. Coste was founded upon the dissection of two uteri at the twentieth and twenty-fifth days after fecundation. The difference betwen the opinions of M. Coste and Mr. Goodsir is that the one considers the decidua reflexa to be formed directly from the decidua vera, while the other believes it to be produced from a plastic layer exuded upon the surface of the decidua vera. Fio. 38. Fig. 39. Fig. 85. First stage of the formation of decidua reflexa. Fig. 39. More advanced stage of decidua reflexa. When first formed, the decidua reflexa appears to differ from the decidua vera in being composed chiefly of cells, while the decidua vera is characterized by the presence of the tubular glands of the uterus. The portion of the cavity of the uterus— or, rather, of the cavity of the decidua—not occupied by the ovum, contains a fluid secretion, exuded from the hypertrophied mucous membrane, or decidua vera, of an albuminous character which, in the early part of gestation, ministers to the nourish- LEE AND OTHERS ON THE DECIDUA. 113 ment of the ovum. This is the hydroperione of Breschet. Dr. Robert Lee believes that blood passes through minute openings in the decidua reflexa from the placental cells and the cells of the chorion, to be taken back into the maternal vascular system, through openings on the internal surface of the decidua vera, without being followed by the escape of blood. The internal surface of the decidua vera is smooth, but the external surface. or that in contact with the fibrous structure of the uterus, has been examined and described by Dr. Montgomery, who found it to consist of a number of cup-like elevations, or little bags, con- taining a whitish fluid, and which present open mouths on the side of the uterus. Dr. Montgomery terms these processes uterine cotyledons. They are best seen at the second or third months, and disappear with advancing pregnancy. Possibly these appearances may be the utricular glands of more recent observers. In cases of double uterus, in which only one is impreg- nated, a decidual membrane is sometimes found in the empty cavity, and it is occasionally, though not always, found in the uterus in cases of extra-uterine gestation. Considerable differ- ence of opinion obtains as to whether the decidua lines the Fal- lopian tubes or not, but the weight of authority is against its doing so. The decidua vera increases with the development of the uterus, but after the adhesion of the ovum to the site of the future placenta, its chief development is at this part, and the De- cidua Serotina, as the portion of the decidua vera entering into the formation of the placenta is called, becomes the most important part of the decidual membranes. The rest of the de- cidua vera becomes a comparatively thin layer lining the whole surface of the uterus, except at the cervix uteri, and the angles at which the Fallopian tubes enter the cavity of the fundus. In the early months, the space between the decidua vera and deci- dua reflexa forms a cavity which has been already referred to, and which is called the decidual cavity. As the uterus is, up to a late period of pregnancy, considerably larger than the con- tained ovum, the cavity between the decidual membranes con- tinues to exist beyond the middle of gestation. In cases of doubtful pregnancy, or where pregnancy has not been suspected, the uterine sound has been passed into the uterus nearly to the fundus without inducing labor or causing haemorrhage. The in- strument, of course, passed through the mucous plug of the os 8 114 FORMATION OF THE CHORION. uteri into the decidual cavity without producing any laceration. I know of a case in which the walls of the uterus and abdomen were so thin that the limbs of the child could be felt with great dis- tinctness, and extra-uterine pregnancy was suspected. One ground for this diagnosis was, that the sound had been repeatedly passed into the uterus without causing mischief. Of course, it would be very wrong, in any case in which pregnancy w,as sus- pected, to pass an instrument into the decidual cavity, as there would be great risk of detaching the placenta. The external surface of the decidua reflexa and the internal surface of the de- cidua vera become at length so smooth that they have been compared to serous membranes. In the latter months, the ovum entirely fills the uterus, so that the whole aspect of the decidual surfaces is brought into contact, and it is often difficult to divide the two, in the attempt to induce premature labor by separating the membranes from the cervix uteri. At the time of parturi- tion, the amnion, chorion, and decidua reflexa are expelled with the placenta, but the decidua vera is subsequently broken down, and escapes, in the form of detritus, with the lochial dis- charge. The other envelope which the foetus derives from the mother is the Chorion, which is internal to the decidua and is formed before the ovum enters the uterus. When the ovule escapes from the ovisac, it is surrounded by part of the granular mat- ter forming the proligerous disc. After fecundation, and as the ovum is passing down the Fallopian tubes, it acquires, according to Valentin, Mr. Wharton Jones, and other observers, an albu- minous layer, which becomes adherent to the vitellary mem- brane, or the outer covering proper to the ovule. The album- inous layer thus formed, which is the commencement of the chorion, is considered by many authorities to be the analogue of the white of the egg, which is formed round the yelk in the egg of the bird, during its passage through the oviduct. It is uncertain whether the chorion is formed, in whole, or in part, be- fore or after the act of fecundation. It is probable however that in the case of ova which never become impregnated, the vitellary membrane becomes coated with a layer of albumen. The chorion is also found in cases of extra-uterine gestation, when the ovum becomes attached to the intestines or the ovarium. Mr. Goodsir is of opinion that the decidua reflexa THE VILLI OF THE CHORION. 115 also contributes, with the chorion, to form the counterpart of the white of the egg. In the first instance, the albuminous chorion is itself a supply of nutritive material for the ovum ; but it soon becomes converted into an absorbent organ, and obtains nutriment from the decidua and the decidual cavity. When first formed the external surface of the chorion is smooth ; but in the earliest state, at which this membrane has been seen in the uterus, it has been found covered with* villi, which present a shaggy appearance, and are devoted to the absorption and assimilation of material for the support of the embryo. Each chorionic villus is bulbous in shape, and consists of an external membrane, including within it a number of cells, which are the principal agents in effecting absorption. At first these villi pre- sent no blood-vessels, but draw nutriment from the elements with which they are in contact by endosmosis, like the spongioles of a jrtant. Afterwards, when the allantois, with the umbilical artery and vein has approached the chorion, the villi contain vessels which become largely concerned in the nutrition and growth of the foetus. In the second month the villi of the cho- rion are of considerable size, and their cellular cavities commu- nicate freely with each other over the whole surface of the chorion. After the end of the second month, they diminish in size except at the site of the placenta, the diminution proceed- ing from below upwards, until the whole of the unattached sur- face of the decidua reflexa and chorion become smooth. By the end of the fourth month, the villi of the chorion on the side opposite to the placenta have quite disappeared. Dr. Robert Lee believes that before the fifth month the cells of the chorion contain blood, which is poured into them from the cavernous structure of the placenta. The villi of the chorion do not be- come developed into the villi of the placenta, hereafter to be described, but form the most internal portion of these villi. With respect to the formation of the Placenta, it will be re- membered, that in the preceding lecture we had described the Allantois arising from the caudal extremity of the foetus, and conveying the bloodvessels, constituting the future umbilical vein and arteries, towards the surface of the ovum. At the same time that this occurs, the decidua vera and d*ecidua re- flexa are acquiring considerable thickness at the point towards which the allantpis is bearing the vessels, and a correspond- 116 CURLING ARTERIES OF TUE UTERUS. ing development of the villi of the chorion occurs in the same situation. From these elements the future placenta is de- veloped. In obedience to the wonderful formative force which presides over all the operations of the embryo, the thickening of the decidua vera, and chorion, occurs upon the same aspect of the ovum, and towards this locality the allantois also directs itself, conveying thither the umbilical vessels. This occurs with almost unerring regularity, and in the fully formed placenta the umbilical cord is generally implanted in or near the middle of the placentary mass. Sometimes, however, the umbilical ves- sels are inserted towards the edge of the placenta, and rare in- stances are met with, in which the allantois projects the vessels towards the wrong part of the chorion, when the ovum perishes from a dislocation, so to speak, between the umbilical, chorionic, and decidual portions of the placenta. It is to Mr. Goodsir that we are indebted for the latest and best account of the •ar- rangement of the chorion, decidua, and maternal and foetal ves- sels in the placenta, and in describing them I shall chiefly fol- low that able anatomist. If the uterine arteries and veins are examined in the gravid uterus while in connection with the placenta, it is found that the uterine arteries pass from the walls of the uterus, into and through the thickened decidua serotina. While passing through the decidual layer, the arteries make a serpentine twist, and hence are called the curling arteries of the uterus. They con- vey the maternal blood into large cellular chambers, which, as described by William Hunter, communicate with each other throughout the whole of the middle portion of the placenta. The blood is returned from this, which Dr. Robert Lee has called the cavernous structure of the placenta, by the uterine veins, which, as they enter the uterine walls, are dilated into sinuses of considerable size. These vascular cells, situated between the uterine arteries and veins, form in the aggregate, an extensive placental cavity, or cavernous arrangement. Such is the entire circuit of the maternal portion of the blood in the placenta. The arteries, cellular chambers, veins, and sinuses are lined throughout with a membrane continuous with the lining membrane of the vascular system of the mother. The large placental cells which have been spoken of as receiving the arterial blood from the uterus, and returning it by the veins, FORMATION OF THE PLACENTA. 117 may be said to stand in the place of the capillaries in other parts of the body. The placenta itself is nourished by special capillary vassels, which enter it from the uterus. In immediate contact with the uterine surface, cellular bands are found cross- ing the sinuses, and threads of a similar character cross the cells or cavities of the placenta, and are attached to the placen- tal villi, hereafter to be described. These bands and threads, which consist of files of cells, similar with the cells exuded from the surface of the decidua at the commencement of gestation, will have to be reverted to presently. The whole of the placen- tal vascular apparatus, on the side of the mother, may be said to be developed in the hypertrophied and metamorphosed mucous membrane, or decidua; and, in fact, the vascular apparatus and decidua form together, the whole of the maternal portion of the placenta. The fcetal half of the placenta is found to consist of tufts arranged in an arborescent form; of villi, which are attached to the branches of the tufts; and of the ramifications of the umbilical arteries and veins. The vessels of the tufts consist of a branch of the umbilical artery, and of a radicle of the umbili- cal vein. The foetal blood enters by the arterial channel, pass- ing out by the veins; but between each branch of the artery and vein there runs, not an ordinary capillary, but a capillary vessel of large diameter, capable of carrying five or six blood globules abreast of each other. These peculiar vessels enter the villi, sometimes dividing and uniting again in the substance of the villi; at other times, one vessel passes into a single villus, or into two or three villi, and returns to the vein without dividing. These large capillaries present, in their course, dilatations and contractions similar with those found in an intestine. The fcetal blood, coming to the placenta by the umbilical arteries, which carry the venous blood of the foetus, passes through the inter- mediate vessels which have been described, and is returned by the umbilical veins, after having undergone, in the placental tufts and villi, the changes necessary to fit it for the support of the foetus; but there is no co-mingling of the two streams of foetal and maternal blood. The two sets of vessels are entirely separate, as was first demonstrated by William and John Hunter. As the uterine arteries and veins have developed themselves in the decidua, so the umbilical arteries and veins have ramified in 118 RESUME OF THE ANATOMY OF THE PLACENTA. the chorion and its villi, by a process similar with the formation of the first bloodvessels in the area vasculosa. Thus, to resume briefly, the placenta is formed by the fusion of the chorion and decidua at the site of the attachment of the ovum to the uterus. The villi of the chorion, capped with a layer derived from the decidua, form the villi of the placenta. On the side of the mother, the vessels of the placenta consist of arteries and veins, with a series of cavernous cells between them. These cells in the aggregate, form what has been termed the pla- cental sac or*cavity. On the side of the foetus, the vessels con- sist of branches of the umbilical arteries and vein, with the large capillary vessels of the villi of the placenta between the two. The maternal portion of the placenta is formed by the decidua serotina, or developed mucous membrane of the uterus, the arteries and veins which enter the decidua from the uterus, the cavernous structure of the placenta, the blood circulating in these vessels, and the external layer of microscopic cells cover- ing the placental villi. The foetal portion of the placenta is formed of the chorion and its villi, the latter forming the inter- nal portion of the placental villi, and of ramifications of the umbilical arteries and veins. In the process of the formation of the placenta, the chorion and decidua first become applied to each other. On the maternal side, at the site of the placenta, the uterine vascular system is developed in the way which has been pointed out. On .the foetal side, the allantois projects the vessels which afterwards become the umbilical arteries and veins Fia. 40. 1, Substance of the uterus; 2, Cavity of a sinus ; 3, 8, Vital tufts dipping into sinuses • 4 Deci- dual lining of the uterus ; 5, Curling artery of the uterus. ' * to the chorion ; and in the chorion a vascular system becomes developed in connection with the umbilical "vessels which ANATOMY OF PLACENTAL VILLI. 119 together constitute the fcetal portion of the vessels of the pla- centa. To understand the intimate connection with, and yet perfect separation from, the maternal and fcetal circulations in the pla- centa, and the mode in which the foetus is nourished after the formation of the placenta, it will be necessary to describe a separate tuft of placental villi, or a single villus itself, the tuft being made up of an assemblage of villi. Each villus consists of its bloodvessel, a double-series of cells, and its envelopes. The capillary is the central portion of the villus. Immediately around the vessel of the villus a layer of cells, derived from the chorion, is found. These cells are bounded by a fine membrane, which, in the early development of the embryo, constituted the external membrane of the villi of the chorion, but which, at a later period, forms the internal membrane of the placental villi. This part of the placenta villi—that is the internal layer of cells, and the internal membrane—is, in fact, the remains of the original villi of the chorion. Fig. 41. 1, Decidua serotina; 2, A venous sinus passing obliquely through it; 8, A curling artery passing through the decidua from the uterus ; 4, Lining membrane of maternal vascular system; 5, Tuft of foetal portion of placenta; 6, and 7, Connection of tufts with each other and with the decidua serotina. On the outside of this inner membrane a cavity, or interspace, is met with, and, surroundiug the space, there is a second layer of cells. The bands and threads found traversing the venous sinuses and the cavernous structure of the placenta, have already been mentioned. Mr. Goodsir ascertained that these bands or threads are composed chiefly of cells, and are connected with 120 THE VTLLT, PULMONARY CAPILLARIES. the external cellular layer of the placental villi. He describes them as being, together with the external layer of cells belong- ing to the villi, the remains of the most internal portion of the decidua; and the external layer of cells represents, in his opinion, the remains of the secreting mucous membrane of the uterus, as it existed before the descent of the ovum through the Fallopian tube. Still more externally, each tuft of villi, or every single villus, is covered by the membrane lining the cavernous structure of the placenta, and which has been de- scribed as continuous with the lining membrane of the vascular system of the mother. Each tuft or villus projects into some part of the extended vascular cavity which exists between the uterine arteries and veins; and Dr. John Reid found that in some instances small tufts of villi entered the uterine sinuses, and could be drawn out from them without laceration. Fi&. 42. 1, External membrane of placental villus ; 2, External cells of villus ; 8 8, Germinal centres of external layers of cells; 4, Space between the maternal and foetal portions of villus; 5, Internal membrane villus, or external membrane of chorion; 6, The internal cells of the villus, the cells of of the chorion ; 7, Loop of umbilical vessels. Thus, each villus is composed of a bloodvessel, a layer of cells, and a fine membrane, derived from the chorion ; of a second layer of cells, and a second membrane, derived from the decidua; with a small cavity between the two; the whole of these structures being inclosed in the blood membrane of the mother. Thus formed, the villi lie in, and are bathed by, the maternal blood passing from the curling arteries of the uterus to the uterine sinuses, through the great placental cells. Con- sidering the placenta with reference to its lung function, the stream of maternal blood represents the atmospheric air, and the vessels of the villi take the place of the pulmonary capilla- ries. The blood is presented to the villi in the maternal chan- nels in a perfectly arterial form, since there are no capillaries on THE PLACENTA, THE LUNG OF THE FC2TUS. 121 the maternal side of the placenta, except those of the small nutrient vessels of the placenta itself; and the changes usually occurring in the passage of blood from the left to the right side of the heart are here effected by the capillaries of the villi and tufts, or the foetal portions of the placenta. It may be said that the fcetal portion of the placenta is an apparatus for projecting a set of foetal capillary vessels into a portion of the maternal cir- culation, which contains no capillaries, and where the capillaries of the villi become interposed between the maternal arteries and veins, in such a manner as, without any actual vascular con- tinuity, to convert to the uses of the foetus those changes which, in the systemic capillaries, are made subservient to the nutrition and renewal of the tissues of the different parts of the body. The capillaries of the foetus become, in effect, in the placenta, a portion of the capillary system of the mother. In another sense, the fine blood membrane covering the villi, and the vessels of the villi, represent the lining membrane of the air vesicles and the pulmonary capillaries, and, by the processes of endosmosis and exosmosis, oxygen passes into, and carbonic acid and other excrementitious matters escape from, the fcetal circulation. Though the placenta is commonly spoken of as the lung of the foetus, the changes effected in it, as far as the oxygenation of the blood is concerned, is more closely allied with the action of the gills.of the fish, the blood of the mother representing the water passing through the branchiae, but being more highly oxygen- ated. The pulmonic or bronchial function is not the only one per- formed by the placenta in foetal nutrition and excretion. The layers of cells derived from the decidua and chorion, and the vessels of the villi, are also analogous in function with the cells and lacteals of the villi of the intestinal tube. The external or maternal layer of cells is believed to grow continually by the assimilation of material from the blood of the mother. As these cells arrive at maturity, they burst, and their contents, which are of a milky appearance, are passed into the space between the two layers of cells, new generations of cells being formed to succeed them, from the germinal spots found in the villi. Thus the ruptured cells are replaced by others, and, in microscopical examinations of the villi, cells of different sizes, from mere nuclei up to fully-formed cells, are constantly found. The chy- 122 SHAPE OF PLACENTA. mous fluid, thus elaborated by the first layer of cells, and passed into the space between the two layers of cells, is next Fia. 43. Section of fully-formed placenta, with part of the uterus, o, Umbilical cord; 6, &, Section of uterus ; c, c, c, Branches of the umbilical vessels ; d, d, Curling arteries of the uterus. assimilated to a further and higher degree, by the internal and fcetal, or chorionic layer of cells, as in the former case, by the growth and rupture of the cells, and the chylous material produced is absorbed and carried into the fcetal circulation by the vessels of the villi. The placenta may be said, therefore, to perform in the foetus the functions of the lungs and the intestinal canal. In some of the lower animals, the connection between the parent and the ovum is much less complicated than has here been described. In the bitch, for instance, Dr. Sharpey found that the glands of the mucous membranes enlarged, and that into their cup-like cavities, pro- cesses of the chorion, or large single villi, were received and became adherent during gestation. The human Placenta is, at the full term, round or slightly oval in shape, its average diameter being from six to eight inches, and its circumference from eighteen to twenty-four inches ; in thickness it varies from one inch to two inches accord- ing as it may be full or empty of blood. The internal surface of SIZES OF THE PLACENTA. 123 the placenta is smooth, and covered by a layer of the amnion and cliorion. Through these membranes the branches of the umbilical arteries and vein are seen ramifying and dividing in every direction towards the circumference of the placenta before they disturb the substance of the organ. The umbilical cord is generally inserted into, or near, the middle of this aspect of the placenta, but sometimes it is attached near the edge, forming what is called battledoor placenta. The external placentary surface, that, namely, in contact with the uterus, is covered with a thick layer of decidua, the decidua serotina. This surface is divided irregularly into a number of lobes, between which pro- cesses of the decidua slip down. When the placenta is expelled after labor, the divisions between these lobes are sometimes dis- tinctly seen, owing to the laceration of the decidua which occurs on the separation and expulsion of the placenta from the uterus; but when gently peeled from the uterine surface, it is covered by an unbroken layer of the decidua serotina, marked by the open- ings of the decidual arteries and veins. The openings of the arteries are circular, some of them being as large as a goose- quill ; while the openings of the veins are oval, and of consider- ably larger size. At the end of the second month of pregnancy the placenta occupies about one-half of the entire surface of the ovum. As gestation advances, the placenta increases in size, particularly in thickness, but the increase is not in the same ratio with that of the uterus or the other parts of the ovum. At the time of labor it extends over about one-fourth of the entire cavity of the uterus. It must be said, however, that the placenta varies very much in size. As the rule, children with whom there is a large placenta are strong and well nourished, while the contrary obtains in the case of thin and small placentae. Large placentae increase the risk and danger of haemorrhage after parturition, which rarely occurs when the placenta is con- siderably below the average size. It is doubtful if the placenta possesses nerves or lymphatics. Its nervous matter, if any, is probably diffused throughout its structure, as in the case of the lower classes of animal life, in which nervous functions are per- formed without the existence of any special nervous system. The placenta, at the full period, frequently bears upon its sur- face and structure evidence of its caducous character. This has been made known more especially by the original researches of Dr. Robert Barnes, followed by those of Dr. Druitt. The cir- 124 PLACENTAE OF TWINS. cumference of the placenta is often marked by a rim of yellow- ish material, consisting partly of fibrine and partly of fatty mat- ter, and indicating the diminution of the area of the placenta in the latter months by a process of fatty degeneration. The uterine surface of the organ is frequently rough and gritty to the touch, from the deposit of earthy matter, chiefly carbonate and phos- phate of lime. Patches of a lighter colour than the rest of the placenta are often seen upon its surface: these spots consisting of fatty matter, and single villi and vessels in the interior, give unmistakable evidence of commencing degeneration. In the case of plural births, it generally happens that each child possesses its own involucra, and a separate placenta. Sometimes the placentae are attached to different parts of the uterus, but most frequently the twin placentae are side by side, the one apparently fused into the other to some extent, but with- out any vascular inosculation between them. In rare cases there is but one placenta, or the umbilical vessels of the twin or trip- let children anastomose before their distribution to the placentae ; and cases have been met with in which there has been but one cord at the placental surface, and one placenta, the cord dividing to pass to the separate children. The Umbilical Cord, or Funis, furnishes the channels of communication between the placenta and the foetus. At the end of gestation, the cord varies very much in length. In some cases it does not exceed six or seven inches, while in others it has been known to measure five or even six feet. It contains the two umbilical arteries and the umbilical vein. The vein is much larger in diameter than the two arteries together, but the arteries are much longer than the vein. No doubt the blood impelled by the fcetal heart, moves faster in the arteries than in the veins, so that the same quantity of blood passes through both. The vein in the umbilical cord and in its ramifications in the placenta is without valves, and conveys the purified blood and nutritive material from the placenta to the foetus. The arteries convey the impure blood of the foetus to the placenta. In these particulars the umbilical arteries and veins resemble the pulmonary arteries and veins of the adult. Both arteries and vein are arranged in the cord in a spiral manner, the arteries being much more twisted than the vein, and coiling round it. The direction of the spiral turns made by the vessels is almost constantly from left to right. Sometimes a single or double ANATOMY OF THE FUNIS. 125 knot is tied upon the cord, at others it is twisted once or twice round the neck, or it is coiled round the body and extremities, so as almost to resemble the Laocoon. The foetal pulse is read- ily felt in the cord when the child is alive and before the funis has been separated. It occasionally happens that only one artery is met with instead of two, and cases have been observed in which the cord has contained two veins.' The arteries do not communicate except by a branch near the surface of the pla- centa. Usually, the vessels divide on entering the placenta, but sometimes division commences before they reach that organ, a circumstance which commonly diminishes the strength of the cord. The bulk of the funis is made up of gelatinous matter inclosed in cells which do not communicate freely with each other. The contents of these cells surround the vessels, and are means of defence against pressure. The quantity of gelatinous material varies much in different embryc-s, and to this is chiefly due the thickness or thinness of the cord. The funis is also covered by a layer of chorion, and externally by a layer derived from the amnion. It is doubtful whether the cord contains lymphatics or nerves, or, at all events, if the nervous matter assumes a separ- ate form. In this place a word may be said about the transmis- sion of impressions from the mother to the foetus. The absence of nerves in the placenta and funis would be no disproof of a communication between the nervous system of the foetus and the mother. When the ovum consists of the blastodermic vesi- cle, and before the beginnings of the nervous system have been evolved in the course of development, it manifests properties which afterwards belong to the nervous system. In the unicell- ular animalcula, the same functions are performed which in higher animals, where the nervous system has assumed a separ- ate type, are executed by the nerves. In these peculiar organ- isms, the nervous system, though not collected into tubes, or surrounded by neurilemma, pervades the whole animal. This may be the case with the umbilical cord and the placenta, or future research may demonstrate the existence of nerves in these temporary structures. No explanation has been given of the spiral arrangement of the vessels of the umbilical cord. When the cord is first formed, the vessels take a straight direction from the foetus to the deci- dua, and the arteries and vein are not close together. After a 126 CONVOLUTIONS OF THE FUNIS. time they become coiled round each other, and the cord dimin- ishes in size, but increases in length. This increase is greater in the early and middle months of pregnancy than subsequent!}7-, so that at the middle of gestation the relative length of the cord is greater than it is at the time of parturition. The same remark may be made respecting the quantity of the liquor amnii. When the cord is long, and the amount of liquor amnii consid- erable, it is easy to conceive that the foetus may, by it own movements, or the changing positions of the mother, pass through a loop in the cord, and thus form a knot. In the same way the passing of the cord round the neck or body has been explained. It appears to me that this explanation may be extended to the curious spiral arrangement of the vessels, and of the whole cord. The cord is originally straight, and can only have been twisted by the movements of the foetus, the placenta being a fixed point. It would seem that the foetus, when it moves, always tends to move in a certain direction, and that the number of spiral turns Fig. 44. The umbilical cord and external surface of the placenta. The amnion and chorion raised from one portion of the placenta. in the cord must represent the number of times which the foetus has slowly rotated in the uterus during the course of ^station. In no other way can we explain the alteration of the vessels from the straight to the spiral form. I shall have to revert to this subject when treating of the movements of the foetus in utero. LECTURE VIII. SIGNS OF PREGNANCY. Gentlemen :—The changes induced in the female economy by pregnancy are very various and extended. From the initial steps in the act of reproduction to its final close, a great number of phenomena occur in different and remote organs. The evi- dences manifested in the generative system are, no doubt, the most important; but the vascular system and its contained fluid, the different portions of the nervous system, the digestive apparatus, the skin, and the glands and their secretions, all con- tribute to the sum of those organic and functional conditions which we group together as the Signs of Pregnancy. The difficulties attending the diagnosis in particular cases are mani- fold. We are frequently asked for a positive opinion at an early period of gestation, when the signs are not pronounced with distinctness. The symptoms vary in different women, or in the same women at different times. Some of the more obvious signs may be wanting altogether, or they may be simu- lated by disease. Difficulties often arise from the mental condi- tion of the patient. We have at one time to deal with women extremely desirous of having children, or, again, with women who hold pregnancy in horror. In another class of cases our dictum is required when the most violent protestations of chas- tity are made. Under these various circumstances, women magnify certain symptoms, and suppress others, as far as possi- ble, in accordance with their own wishes, or in order to deceive the attendant. We should, to use a legal phrase, " dismiss from our minds," in any case of doubtful pregnancy coming before us, all considerations except those of a physical character. Gooch expressed this when he said, with more force than ele- gance, that not " women's words, but their bellies " should be believed in suspected cas,es. 128 IMPORTANCE OF THE SIGNS OF PREGNANCY. It is of importance, not only that accoucheurs, but all medical men, should pay attention to the signs of pregnancy; otherwise the practitioner may be confounded by the birth of a child, when no increase of the population had been expected ; abor- tion may be produced unwittingly by emmenagogues or examin- ations ; or, under the false impression that pregnancy exists, serious disease may remain for months untreated and unchecked. In all cases which admit of doubt, the medical attendant will do well to suspend any positive judgment until the evidence one way or the other becomes certain, and, in the meantime, to be cautious in all that relates to the treatment and management of the patient. The most convenient method of relating all that pertains to the signs of pregnancy is to consider them very nearly in the order in which they arise, by which means a double advantage will be gained; the symptoms of commencing and advanced utero-gestation will be grouped separately, and a method of ex- amination will be fixed upon the mind. The first indications of pregnancy are to be found in the reproductive organs. No sooner has a fruitful congress taken place than a change in the condition of the Uterus occurs—from a state of comparative quiescence, in which, apart from men- struation, the decay and repair common to all other tissues is its only function, it emerges into energetic activity, constructs a nidus for the reception of the expected ovum, and commences those intimate changes which result in the transformation of a fibroid mass into a muscle of immense energy. The greater the functional activity of an organ, the greater the amount of blood which passes through it in any given time. The uterus is no exception to this general law, and hence, when an examination is made per vaginam but a few days after conception, the organ is found hot, turgid, and almost erect, as if endowed with the properties of erectile tissue. This state of the uterus is by no means persistent; before any great length of time it gives way to softness and increased bulk; the uterine vessels increase in size from day to day; small twigs of artery become developed into vessels of considerable calibre; there are capillaries where none apparently existed before; the cellular tissue of the oro-an is in a manner unravelled by the dilated and dilating vessels, as well as by certain histological changes, and the parenchyma is LOCAL SIGNS OF PREGNANCY. 129 moistened by interstitially-effused serum. The body of the im- pregnated uterus is, in all ordinary cases, slightly anteverted during early pregnancy, and the enlarged body of the organ may be felt by the experienced finger in the anterior vaginal cul de sac. A soft and cushiony state of the os uteri, with the detection of the dense body of the uterus between the anterior lip and the pubes, are amongst the earliest signs which lead us to believe in pregnancy. The unimpregnated uterus may be anteverted, but this condition is not attended by a soft condition of the os uteri. Examined with the speculum, the os and cervix uteri are somewhat increased in size, the tissues appear less dense than in the impregnated state, and the white plug of mucus is dis- tinctly visible in the lower parts of the cervical canal. Owing to the permanent condition of the plug during gestation, and the increased acidity of the vaginal secretion, the mucous plug is more firmly coagulated, and is of a more intensely white color than usual. Suspension of the Catamenia is commonly the first symp- tom of pregnancy which arrests the attention of an intelligent female, wTho has exposed herself to the possibility of impregna- tion, and is perhaps the one in which women most firmly rely, especially if any abdominal enlargement coincides with the absent function. Its value as evidence of utero-gestation is modified by the fact, that the suspension of the menses, although tolerably constant, is liable to many aberrations, and is indica- tive of other conditions than pregnancy. Menstruation may continue through a part of, or the whole term of, utero-gestation. Cases in which it has appeared once after impregnation are re- corded by Johnson, Puzos, Desormeaux, Dewees, Stein, and Gardien. Burton, Maunsell, Campbell, and others, mention cases in which it appeared three, four, and six times, and similar instances have fallen under my own observation. There is a case detailed in Hebernden's Commentaries, in which the func- tion persisted during the whole term of pregnancy, and Deven- ter, Hosack, and Haller, testified to the occasional appearance of the phenomena. Deventer and Baudelocque speak of females in whom the catamenia appeared only during pregnancy, and a still more remarkable abnormality has been witnessed in some women, who have performed this function for the first time sub- 9 130 PHYSICAL SIGNS OF PREGNANCY. sequent to impregnation. The necessity of preserving the out- ward appearance of virtue has instigated women to feign themselves " regular " by smearing their persons and staining their linen periodically. Belloc mentions such an instance, and suggests that if the vulva is washed, and the discharge does not reappear, the case should be suspected. An exactly opposed series of cases to those we have been con- sidering is constituted by instances in which the catamenia are suspended, and pregnancy does not exist. Cold, shocks of any kind, exhausting discharges, incipient phthisis, the worst forms of ovarian disease, and several other circumstances, frequently suppress this function. Women who are nursing, as a general rule, do not menstruate, and, as the catamenial climacteric approaches, intermissions, even of several months, are frequent. There are cases again in which the history of the menstrual function is of no use whatever in determining the question of pregnancy. Some women prove pregnant before menstruation has ever occurred; some after it has apparently ceased alto- gether ; and others at a time when the function has been sus- pended for several periods by known causes, such as lactation. The best rule, perhaps, for applying the catamenial test to cases of suspected pregnancy, is that if the suspension has persisted for several months, if, at the same time, the health has not suffered, and if the person is not giving suck, the probability that she is pregnant has reached the highest point to which it can be brought by evidence from this source alone. Various derangements of the Digestive Organs usher in pregnancy. The exact period at which they occur is various and uncertain. In some women nausea follows close upon the heels of conception; in others, no gastric sympathies appear until two or three months have elapsed; but from the second to the fifth or sixth week is the general period at which they are established. They usually decline about the fourth month; but their disappearance is liable to the same uncertainty as their in- vasion. Nausea, vomiting, eructations, heartburn, a peculiar sense of sinking at the epigastrium, cravings for peculiar or par- ticular articles of diet, and antipathies to other comestibles are the ordinary manifestations of gastro-uterine irritation observed. In general, the nausea, vomiting, and sinking occur upon the first rising, or assuming the erect posture, and persist only for a PHYSICAL SIGNS OF PREGNANCY. 131 short time. The comparative universality of this rule has caused these symptoms to be expressed by the term morning sickness, a phrase which has become almost vernacular. It is obvious that the causes of gastric derangement, similar with those alluded to, must be numerous ; and hence, except as cor- roborative proof, we can throw little light upon the diagnosis of a case of doubtful pregnancy by discovering that sickness has occurred in the morning, or that an affection has been shown for chalk, slate pencil, or some previously abhorred article of diet. The value of this, as of several other signs of pregnancy, rests upon its coincidence with other recognized signs. The synergic action between the stomach and the uterus, both as re- gards secretion, sensation, and motor action, are amongst the most remarkable phenomena of reflex nervous action. In the case of the gastric irritation of pregnancy, it is worthy of re- mark, that it is during the early months that the affection is most common and constant. It is probably caused by the dis- tension and evolution of the dense structure of the uterus after impregnation, or by the pelvic irritation caused by the gravid uterus before it emerges from the brim, or from both these causes. Certain Glandular Sympathies are excited during pregnancy, of which one of the most remarkable results is Salivation. This form of salivation is, of course, quite distinct from mercu- rial or other metallic affections of the salivary glands, differing in the absence of foetid breath, of sore gums, or the prostration observed in such cases. It is probable that the watery vomitings of pregnant women partly depend on increased pancreatic secre- tion—a supposition which is favored by the analogy between the structure and secretion of the pancreas and the salivary glands and the frequent excitation of the latter during preg- nancy. It has been said that the pancreas is a supplementary salivary gland. Cases illustrating utero-gestative salivation are mentioned by Dewees, Van Swieten, Dr. Blundell and others. In a slighter degree, such cases are not uncommon. When pregnancy is but a few weeks advanced, the Mammae begin to take on certain new actions, preparatory to their per- fection as secretors of a nutritive fluid. The changes which take place in the breasts at puberty may be called the primary evolu- tion of the mammae. This is parallel to, and synchronous with. 132 DOUBTFUL SIGNS OF PREGNANCY. that evolution of the uterus and ovaries which produces the capacity to conceive; and the changes which take place in the mammas after conception constitute their secondary evolution, and are parallel to, and synchronous with, those uterine changes which give the capacity to nourish. The first indications of pregnancy given by the mammae, consist of a certain sense of fullness and weight, with shooting pains, these latter being some- times confined to the gland itself, but at other times extending to the mammilla, where they may be almost constant, producing what is technically called " mastodynia." The afflux of blood to the breast which now takes place, speedily replaces the mere sense of fullness by actual increase of volume; the gland becomes hard, knotty, and tender to the touch, and large blue veins may be seen meandering over its surface, just below the integument. A very cursory examination will suffice to distinguish this condition from the mere increment in bulk attained by persons who are growing corpulent. A deposit of fat does not give the same knotty feel to the breasts ; the vascu- lar supply is not sensibly altered, and a great volume may be acquired without any of those peculiar white, shining streaks appearing on the surface of the integument which are the result of distension by growth of the gland. The most probable embarrassment is likely to occur in women who, having pre- viously borne children, and having reached the threshold of the sexual climacteric, have their menses temporarily suspended, their breasts painful, and their stomachs irritable. Almost any uterine irritation will produce enlargement of the breasts and sympathetic pains. Retention of the menses from an imperforate hymen, fibrous tumours of the uterus, and ulceration of the os and cervix uteri, are frequently concerned in these mammary changes ; and habitual and excessive copulation sometimes has the same effect. These possible causes will, however, be remembered and sought for where any doubt exists. The most characteristic changes are to be found in the nipples and the sur- rounding areolae. The nipples become turgid and more promi- nent, and the discs around them assume a darker hue, more marked in persons of a dark than of a light complexion. Ingleby observes that the cuticle of the areola becomes scaly, and that the general surface of the breast presents a mottled appearance. As pregnancy advances, especially if it be a first MILK, A SIGN OF PREGNANCY. 133 pregnancy, the deposit of pigment in the areolae increases, the areolae themselves become moister, and the follicles studding their surface are prominent, distended, and bedewed with tran- suded fluid. In women with dark hair and eyes the outer part of the circle surrounding the mammilla presents an appearance of small white patches, as if the color had been discharged by a shower of rain. Dr. Montgomery trusts more to the appearance of the follicles, the moisture on the areolae, and the turgescence of the parts, than to the deposit of pigment, which results occasionally from uterine irritation, and not unfrequently is per- sistent after the first pregnancy. The mammillae are sometimes so effectually compressed by tight corsets as never to rise above the level of the mammary surface until artificially drawn out. About the sixth or seventh month numerous white, silvery streaks make their appearance on the surface of the breast; they are exactly similar to those found on the abdomen, and are called linece albicantes. They are in reality the exposed floors of furrows which naturally exist in the skin, and they are unfolded in consequence of the distension of the subjacent gland. Once formed, they do not entirely disappear, and are therefore of little value as a sign of pregnancy, except in primi- parous women. In common with the altered nervous and vas- cular condition of the mammae, their secretive endowments are called into play at a variable period, ranging from the fourth or fifth month to immediately before labor. It may be said, as a general rule, that no secretion of milk takes place until eight- and-forty hours after labor; and on the other hand, there are so many irregularities regarding the secretion of milk, that neither its absence nor presence can be rated at any considerable value, as proof or disproof of utero-gestation. Suppression of the milk in persons who are nursing and liable to impregnation is a more valuable sign of pregnancy than the converse condition. Lastly, it must be remembered that recent abortion and lacta- tion produce the same conditions of the mammae as obtain in pregnancy. The Size and Form of the Afodoineu next arrest our atten- tion in relation to pregnancy. During the first two months, no enlargement is visible, or, if visible, can be trusted, as flatulent distension and other evanescent conditions of the abdominal con- tents produce variations in dimension beyond the possible limits 134 BULK, A SIGN OF PREGNANCY. of any size that may be attained at such an early period. At first, indeed, the belly becomes flatter, and the navel is deeper, as if dragged down by the increased weight of the uterus; there is a French proverb, " en ventre plat, enfant il y a," and in this, as in many other instances, popular belief coincides with scien- tific observation. The traction at the navel is said to be painful occasionally, and the navel itself tender to the touch. About the third month abdominal enlargement becomes obvious in the nude figure, and from this period steadily increases until nearly the end of pregnancy. By the fifth month the navel has become shallower, and the uterus may be distinguished through the abdominal walls ; at the sixth month, it is flattened out; and in another month protrudes beyond the level of the general sur- face of the abdomen. Numerous other circumstances give rise to enlargement of the abdomen. Ovarian dropsy, ascites, cer- tain diseases of the spleen and liver, flatus in the bowels, accumulated faeces, tumors of the omentum, and unusual deposition of fat in the omentum and abdominal walls, as well as hydrometa, hydatids in the uterus, physometra, fibroid and other tumors of the uterus, and intra-uterine polypi, all pro- duce an increase in bulk, which may to a certain extent simu- late pregnancy. It is necessary to observe, that some of these conditions may co-exist with pregnancy. A little care will, however, suffice to distinguish between the above-men- tionedforms of enlarged abdomen andan abdomen distended by the gravid uterus. Such a mistake as that quoted by Gooch from Lowder's MS. lectures, where a practitioner mistook preg- nancy with distended bladder, for ovarian dropsy, and thrust a trocar through both sides of the bladder, and through the walls of the uterus, into the child's head, would be unpardonable at the present day. The history of the enlargement, its form, and the evidence procurable by means of auscultation, palpation, and percussion, ought to preclude the possibility of any grave error in practice. Inquiry will almost always elicit the fact, that in ovarian dropsy the enlargement has at first been on one side, and fluctuation is easily distinguished. In ascites there is a previous history of disease, and the form of the abdomen in the recumbent posture, is widely different from the ovoid belly of a pregnant woman; the contained fluid, in a case of ascites from its obedience to the law of gravitation, produces a bulo-ino- SILVER STREAKS IN PREGNANCY. 135 between the crest of the ilium and the false ribs, the anterior and middle aspect of the abdomen being its flattest part. Enlargement of the liver and spleen increases from above down- wards, and tympanitis is extremely easy of detection. The only real embarrassment arises from those cases in which the uterus itself is distended, and then other symptoms must be referred to, in order to determine the question. The elastic nature of the uterine tumor is simulated by no other abdominal enlargement, and is so far valuable as evidence of pregnancy; but fluctuar tion may be obtained where the liquor amnii is very superabun- dant ; or an ovarian cyst may intervene between the gravid uterus and the surface of the body, so that the absence of the peculiar impression conveyed by palpation is not so negative as the converse is positive. When a blighted fcetus is retained in utero, no further increase in size takes place; and this contin- gency must not be forgotten in forming an opinion as to the con- dition of a woman who has had progressive abdominal enlarge- ment, with other signs of pregnancy up to a certain date, fol- lowed by recession of her uterine sympathies, etc., and arrest of increase in bulk. Silvery streaks appear on the surface of the abdomen when it becomes much distended; once formed they are permanent, but they do not by any means occur in all cases. They are only of use as a sign of pregnancy in first cases, or where long intervals have passed between successive preg- nancies. Dr. Cormack has drawn attention to the dark line which occurs during pregnancy in the median line of the abdomen. It is constant in the latter part of gestation, but being the result of distension, it is present in the case of other abdominal tumors. Reference has already been made to the condition of the uterus immediately after impregnation. During the first three months of pregnancy the lower part of the uterus feels soft and almost oedematous; the os, which had before been firm and with well-defined lips, becomes of a more rounded form, and the tip of the finger can be inserted between them. In first preg- nancies such changes are more marked than in multipara, especially if the parts have beeu at all ruptured during labor. The whole body of the uterus sinks lower down in the pelvic cavity, and the os can be felt, not only lower down, but some- what displaced towards the hollow of the sacrum ; the fundus of the organ is anteverted to a corresponding extent, and it is 136 CAUSE OF THE RISE OF THE UTERUS. partly to this circumstance, as well as to the intimate sympathy between the uterus and the other pelvic organs, that the fre- quent micturition and sense of weight in the rectum, which accompanies early gestation, is attributable. Approaching men- struation or the engorged condition of the womb, sometimes met with in menorrhagia, simulate these earlier changes of preg- nancy to some extent. The body of the uterus can be distin- guished more readily in the anterior vaginal cul-de-sac as preg- nancy advances, and about the fourth month the fundus may occasionally be felt just above the pubis. With its gradual increase in bulk the womb has gradually risen to the pelvb. Many authors state that the uterus rises suddenly out of the basin of the pelvis into the general abdominal cavity. There is,1 however, no real proof that the uterus at once emerges from the pelvis, and there are many circumstances which render it extremely improbable. The idea of the sudden escape of the uterus from the pelvis involves a notion of some great and sud- den increase in the contents of the cavity, or the sudden removal of some impediment. In cases where there is much antero-posterior contraction of the brim, a malformation which involves less contraction of the cavity than most other distortions, permanent incarceration should result at or about the fourth month, if the uterus really remains entirely in the true pelvis until that period; and cases of extreme contraction of the brim or pelvis generally, should have a history of diffi- culty at the time of the supposed emancipation of the womb. No such histories are on record. The real state of the case appears to be, that the uterus rises slowly out of the pelvis, partly because its increase in bulk is from above, the fundus being the first part developed, and the cervix the last; partly because it is in reality a wedge with the apex below; partly because the bladder pushes the uterus upwards every time it is distended, directly, by means of the fluid contained in it, and indirectly, by elevating the vesical layer of the pelvic fascia, to which circumstances may be added the obliquity of the pelvis and frequent changes of position on the part of the mother. About the fifth month the uterus is found to have risen half way to the umbilicus. It is now that the cervix uteri begins to shorten its cavity, being taken up into the general uterine°cavity by a process of development commencing at the junction of the CHANGES OF TOK CERVIX UTERI IN PREGNANCY. 137 cervix with the body of the organ, and terminating at the os itself. The finger may be inserted between the lips of the mouth of the uterus with greater facility as each month passes, and the follicular glands of the cervix may be felt just within. At the same time the orifice of the womb moves upwards and back- wards towards the sacral promontory, and by the time it has reached its most posterior and superior position, the cervix has completely disappeared, the os uteri being a mere rim. Exter- nally, the uterus reaches as high as the umbilicus at the sixth month, half way between the umbilicus and the ensiform carti- lage at the seventh, and as high as the latter structure at the eighth ; after the eighth month the increase in size is more obser- vable in the way of increased tension, and indeed, shortly before labor sets in, it would appear ,as if an actual diminution in size Fig. 46, Os and cervix uteri at the third month of gestation. Fia. 46. Os and cervix at the sixth month. took place. The head, on presenting part of the child, may now be felt through the os uteri. 138 STOLz's VIEW OF THE CHANGES IN THE CERVIX UTERI. Fig. 47. Os and cervix uteri at the eighth month. Fig-. 48. Os and cervix at the full term. [Dr. Smith here gives the prevailing opinion which has been thoughtlessly adopted by writers since it was first promulgated by Smellie, of the manner in which the cervix uteri becomes absorbed and merged in the ovoid form of the womb. I prefer, however, to accept the description given and demonstrated by M. Stolz in 1826, which has received the sanction of the most eminent modern physiologists and pathologists. According to the description of M. Stolz, which is now fully confirmed, instead of this internal opening of the neck expanding and the superior part spreading out downwards during gestation, the reverse takes place. Early in pregnancy, the os and lower part of the neck begin to soften. This softening gradually extends upward, though less rapidly, in primiparae cases. As the ram- ollissement extends from the os upwards, the os and neck expand in multiparas cases, though in primiparae cases the cavity of the neck expands without a corresponding patulence of the os, which gives the neck a spindle shape. The cervix loses but little, if any of its length. By the seventh month, the intra-va- ginal portion of the neck has undergone this change, beino- soft- ened, and the os so dilated in women who have been mothers as to admit readily the first phalanx of the index fino-er. This FIRST MOTIONS OF THE FOETUS. 139 ramollissement and expansion of the cervix progress upwards, so that a few days before full time in its proper course, the circular fibres, closing the internal opening of the neck, become softened, and it dilates. This is shown by the following figures, which we place in antithesis to those of the author.] Quickening generally occurs when pregnancy is advanced about half way ; Denman gave the sixteenth week as the period at which it most commonly occurs, and Dr. Fleetwood Churchill gives nearly the same average; Dr. Ramsbotham places it be- tween the sixteenth and eighteenth week; Puzos had known it to occur at the end of two months, and it has not unfrequently been postponed till the sixth, seventh, and eighth months ; it is in truth, very variable, Levret having recorded an instance in which it did not occur at all. By some authors it is believed that quickening is the first sensation by the mother of the move- ments of the foetus; others have supposed it to be a sudden ascent of the uterus from the cavity of the pelvis. The nature of the sensation will be differently described by different women. The child of Elizabeth is said by St. Luke to have " leaped in her womb," when she heard the salutation of Mary; in some women it is described as a pulsation, and others speak of it as a fluttering or an occasional shock, attended by a sense of faint- ness, sickness, and sometimes a slight sanguineous discharge. The physical cause of the symptom is doubtless motion of the foetus, and the period at which it occurs is most probably due to the increased size and activity of the child, which permit it to come into occasional contact with the walls of the uterus, through the liquor amnii. Accidental circumstances may perhaps give rise to the particular motions first perceived, and it may occasionally happen, that these accidental stimuli being wanting, no perceptible motion occurs. The value of the symptom as a sign of pregnancy depends partly upon whether 140 PERISTALTIC UTERINE MOVEMENTS. the patient has experienced these sensations before, and partly upon the amount of credence to be attached to her statements and opinions. The motions of the foetus having been once established, they may continue to be felt at intervals of variable duration by the mother or by another person. Dr. Montgomery thought he could determine the motions of the foetus before the mother was conscious of them; it must, however, take a very prolonged examination to elicit any information at so early a date, and even then some doubts may be entertained as to whe- ther the observation can be trusted. At a later period, it be- comes very easy to perceive the movements of the living foetus. As the points by which it comes into contact with the uterine walls gradually multiply, more trifling circumstances suffice to set up excito-motor actions; the mere pressure of the hand upon the abdomen will sometimes produce palpable kicks. It is not always easy to distinguish between the movements of the foetus and some other movements which occur in the pregnant woman. The uterus and abdominal walls have special actions of their own. The uterus is subject to peristaltic contractions, which, starting from one end of the organ, traverse its whole extent like a wave. They may be discriminated from the foetal kicks or plunges, by the travelling ridge which they produce, and which may be felt under the hand. At other times, the uterus contracts at certain portions. These contractions shift from one place to another, and convey the impression to the mother that the child's head is moving about. It is the peristaltic actions of the uterus, and not the movements of the foetus, which are pro- duced when the hand is cold or dipped in iced water. The abdominal muscles are subject to involuntary contractions, arising from the irritation which the contact and pressure of the uterus produces, but it is voluntary contraction of the abdominal muscles which most usually stimulates the motions of the child. In the year 1818, a great advance was made in the diagnos- tics of pregnancy. Mayor, of Geneva, published a memoir in the Bibliotheque Universale, on the detection of pregnancy by the pulsations of the foetal heart. This discovery attracted very little attention until four years afterwards, when Kergaradec published a systematic work on Auscultation as applied to preg- nancy ; he added a knowledge of the so-called bruit placentaire CHANGES IN THE UTERINE SOUFFLE. 141 to M. Mayor's discovery. At a later period, Dr. Kennedy dis- covered the funicular pulsations, and Naegele described what may be called " sounds of the displacement of the foetus." Other sounds may be heard on applying the stethoscope to the abdomen of the pregnant woman ; they are the products of mus- cular action. The value of these auscultatory phenomena is very different, but there are no other signs of pregnancy so unequivocal, or upon which we may so safely rely. The subject of utero-foctal auscultation in this country has received its chief development from the writings of Dr. Kennedy, and the translation of Naegele's work on Auscultation by Dr. West. The uterine souffle, bruit placentaire, or placental murmur, as it is called by different authors, is distinguishable before any of the other intra-uterine sounds. Great difference of opinion has existed as to the earliest period at which it may be heard ; a similar variety of opinions has prevailed as to the exact seat of the murmur. Dr. Kennedy averred that he had heard it at the tenth week, while Velpeau states that the mere fact of its having been discovered even at the third month is sufficient proof that, whatever the sound observed may have been, it could not have been produced by the utero-placental circulation. It may be said as a general rule, that until the fourth or fifth month, that is, until the uterus has risen out of the pelvic cavity, the uterine souffle is inaudible; after that period it may gene- rally be heard on any one point of the region of the uterus which is accessible to the ear. The situation of the sound will vary as pregnancy advances; in the earlier part of the second moiety of utero-gestation, it is heard nearer the pubes, and it gradually ascends from week to week. It is seldom heard quite at the fundus uteri or in the lumbar regions. The character of the sound is very different in different persons, and varies in the same individual; sometimes it is a hoarse and sometimes a soft blowing murmur, at others it is a cooing sound, and again, it is sibi- lant or musical. Now it is immediately beneath the ear, and again it is distant. It is synchronous with the radial pulse. It is modified by the pressure of the stethoscope and may disappear and recur again under the instrument. On some days, in the early part of its appearance, it is absent, and on others it is present. What- ever may be the exact physical cause of this sound, there can be little doubt now that it is produced in the walls of the uterus, 142 VALUE OF THE UTERINE SOUFFLE. and not, as Hohl supposed, in the placenta, or as Kiwisch believed, in the epigastric, and others, in the iliac arteries. It may be well to state the foundations for this opinion ; the same sound has been heard in cases of fibrous tumor and vascular sarcoma of the uterus, and in moles; it is often heard over the whole surface of the uterus, accessible to the stethoscope; it persists for a short time after delivery ; it has been heard in cases where putrid foetuses have been born, and the placenta found with its vessels full of thickened and coagulated blood. These reasons appear to be conclusive against the placental theory, and others exist which eliminate the iliac arteries or aorta from the question. If the sound were produced by pressure on the iliac arteries or aorta, it should disappear when that pressure is removed by the assumption of the prone posture, whereas it persists in every posi'- tion ; pressure should intensify the sound if this hypothesis were correct; the contrary frequently obtains, and indeed the murmur not unfrequently disappears under pressure, even when it is made on the anterior aspect of the uterus, directly towards the spine. And finally, the metroscope of M. Nauche, applied to the cervix uteri, in the vagina, transmits the sound when abdominal exam- ination has failed to distinguish it. The sound is heard most dis- tinctly at the usual site of the attachment of the placenta, and this circumstance appears to have misled Hohl and others ; it is, however, only in accordance with the fact that the uterine vessels are largest where the placenta is attached. As a sign of pregnancy, the uterine souffle is extremely valuable ; it can be distinguished from any possible arterial imitation by the absence of impulse, or by changing the position of the patient; and a very simple device will distinguish between it and the vesicular murmur, if the latter should happen to be audible lower than usual; for if the stethoscope be moved gradually up- wards, any lung sound will of course become intensified, whereas the uterine souffle would diminish. The uterine souffle is no proof of the life of the foetus, nor can it be made use of to deter- mine the position of the child, or whether the uterus contains a double foetus. Widely different from the foregoing acoustic phenomena is the double pulsation discovered by Mayor. The ticking of a watch heard through a pillow has been aptly compared with the rapid pulsations of the fcetal heart, as heard through the uterus IMITATIVE SOUND OF THE F02TAL HEART. 143 and abdominal walls. There is a distinct rhythm in these sounds, consisting, as in the perfectly developed individual, of two sounds of unequal length, followed by a pause. The number of pulsa- tions varies, according to M. Jecquemier, from 108 to 160 per minute, but 130 will represent the average frequency of the embryonic pulse. It, however, subsides to a certain extent, dur- ing the last month of pregnancy, a change which is continuous with that well-known declension in the frequency of the pulse which advances pari passu with increasing age. Dr. Hope gives 150 as the foetal pulse at the fifth month, and 120 as that of the ninth month. The beating of the foetal heart may generally be distinguished, for the first time, during some part of the fifth month. At first the sound is very feeble and distant, but by degrees it acquires strength, and the diminution of the liquor amnii, by allowing the foetus to come into contact with the uter- ine walls, facilitates the conduction of the sounds to the ear of the observer. Nothing can be more shifting and variable than the sounds of the fcetal heart—now they may be heard on one side of the abdomen, and now on another; their position even changes during the same examination, and sometimes they sud- denly cease, or rather escape observation, for days together. A like change in their intensity occurs, but frequent observation detects steady increase in their force. Occasionally, they are never heard during the whole of pregnancy, and the absence of these sounds is not conclusive of the death of the foetus, unless they have undergone a gradual declension in intensity previous to their cessation, and even then it is perhaps safer to look for cor- roborative proof elsewhere before coming to a decision. They are accelerated temporarily by the motions of the foetus. The area over which the sounds of the foetal heart may be distin- guished varies according to the force of the heart's action, the amount of liquor amnii, and the position of the child. There is only one possible circumstance which can at all imitate the sound of the foetal heart, and that is, when the sound of the maternal heart, from emotional or other causes, are increased in frequency and force, and conducted through the diaphragm and liver to the uterus; the same device which has been recom- mended for distinguishing between the vesicular murmur and the uterine soufflet will establish the differential diagnosis in this case. 144 FUNIS DISTINGUISHED EXTERNALLY. Dr. E. Kennedy states, that, " in some cases, where the pari- etes of the abdomen and uterus were extremely thin he has been able to distinguish the funis by the touch externally, and has felt it rolling under his finger, and then applying the stethoscope, its pulsations have been discoverable, remarkably strong." Dr. Churchill and Naegele support Dr. Kennedy against Ilaus and Hohl, who deny the fact. The observation, however, although it reflects much credit upon the acumen of Dr. Kennedy, can hardly be of practical use; because, where the abdominal and uterine walls are so thin as to permit us to feel the pulsation of the funis through them, the other auscultatory signs of preg- nancy, and the evidence obtained by palpation, must already have set the question at rest, and except under such circumstan- ces it must be very difficult to discover the funicular soufflet. The sounds of the displacement of the foetus consist of shocks, sometimes quick, like a light tap, and at other times more like a heavy plunge; and there are also friction-sounds, which are evidently produced by the gliding of the surface of the foetus over the inner uterine surface. Naegele avers that these sounds may be heard before quickening has taken place. Ballottement is a means of acquiring information as to the circumstances of pregnancy, first made use of in France. There are two kinds of ballottement, the internal and the external; the first of which is practised by one or two fingers introduced into the vagina; and the latter, by manipulations applied to the sur- face of the abdomen. " Ballotter" signifies " to toss a ball, as at tennis ; and the manoeuvre in question is a kind of tossing up of the foetus in the waters of the amnios. The method of forming the internal ballottement is as follows: The worn; METHOD OF BALLOTTEMENT. 145 placed in bed, with the trunk in a semi-recumbent position, so as to make the axis of the uterus coincide with a line passing per- pendicularly from the fundus uteri to the ground, and to bring the uterus as low down into the pelvis as possible. The bladder and rectum should have been previously emptied. The first or two first fingers of one hand must now be introduced into the vagina, and applied to that part of the cervix uteri, or uterus, which is situated between the anterior lip of the os and the pubis. [The experimenter must be careful not strike the os uteri, as the sensation might be deadened by the length of the neck; and in cases of uterine displacement, where the body was bent upon the neck, percussion upon the neck by jerking the body upon the neck might cause a serious error in the diagnosis.] The other hand, or the hand of an assistant, should then exercise steady pressure on the abdomen ; and a deep inspiration on the part of the patient will finally bring the uterus into the most favorable position for the experiment. Immediate advantage must be taken of the temporary cessation of breathing to make a rapid jerking push against the uterus with the tips of these fingers which are applied to it in the vagina; if there is a foetus in the uterus, and if the proper period of pregnancy has been selected, a hard body will be felt to recede from the fingers as if rising in the intra-uterine fluid, and in a second or two it will fall again on the tips of the fingers. This is the internal ballottement. The period at which it is applicable is from the end of the fourth to the end of the sixth month, as a general rule ; but it must vary according to circumstances, such as the bulk of the foetus, the quantity of the liquor amnii, and the width of the pelvis. When once discovered, it is a tolerably conclusive proof of pregnancy. The external ballottement is best performed by placing the woman on her side, on the extreme edge of the bed, so as to have her abdomen projecting beyond it. One hand should then be applied to the undermost side of the belly, and another to the opposite surface, in order to steady the uterus. If a foetus is present a similar manoeuvre may now be practised, as in the internal operation ; a sudden impulse from the lower hand pro- pelling the foetus towards the upper part of the amniotic sac, from whence it will gently descend again upon the same hand. If the foetus is very small, no sensation will be imparted to the hand by its descent; and if the liquor amnii be scanty and insufficient 10 14G DIFFICULTIES OF BALLOTTEMENT. to float the child, the experiment will entirely fail. Regarded as evidence of pregnancy, the external is very inferior to the internal ballottement. It is not applicable in so early a stage of pregnancy, a much larger bulk being necessarily obtained before the uterus is brought into sufficiently extensive contact with the abdominal parietes for such a delicate manipulation. After the six months of utero-gestation, the quantity of liquor amnii becomes relatively decreased, and the foetus is not so well floated, except in some few cases in which the fluid is preternaturally abundant. A kind of spurious ballottement may be sometimes found in cases of ovarian dropsy, where a pedunculated cyst floats within a larger cyst. The ballottement is no proof of the life of the foetus. It should be mentioned, that great length of the cer- vix uteri, or a footling position of the foetus, will make the inter- nal process difficult, and sometimes impossible. A substance called Kiestcin, which occurs in the urine, is one of the minor signs of pregnancy. So far back as 1486, Savon- arola gave an account of a urinary deposit which was evidently this material; he compared it to carded wool, but did not pur- sue its history beyond this point. MM. Nauche and Eguisier, in publishing their supposed original discovery of this matter, made use of Savonarola's simile, speaking of it as a cotton-like cloud, and they gave a further detail of the transformations it goes through, which are as follows: The cotton-like cloud, in the course of from two to six days, becomes resolved into a num- ber of minute opaque bodies, which rise to the surface, forming a fat-like scum; this persists for three or four day^s; the urine then becomes very turbid, and minute flocculi detach themselves from the crust and sink to the bottom of the vessel, until the whole pellicle disappears. This crust never becomes mouldy, and never lasts more than three or four days. The pellicle con- tains crystals of triple phosphate, fat, and a peculiar nitroge- nous body allied to casein. It is supposed that during preg- nancy the mammae secrete a certain quantity of abortive milk, if the expression may be allowed, which is again taken up into the circulation, and excreted by the kidneys. Analogous facts exist regarding other secretions. Casein has been found in the blood by MM. Grullot and Leblance during lactation, and thus an additional probability has been given to the truth of this hypothesis. When kiestein is present in the urine it persists VARIOUS SIGNS OF PREGNANCY. 147 from the end of the first month to delivery. A minute investi- gation of the exact nature of the body, and the opinions of all writers on the subject, is unnecessary; but the following consid- erations will point out how far it is really valuable as affirmative or negative of pregnancy. It has been found in the urine of women not pregnant. It is found, for instance, in the urine of women taking cod-liver oil; it is not always to be found in women who are with child. There are a great variety of miscellaneous evidences of pregnancy, many of which are not constant enough to be of any great value, unless they have occurred in former pregnan- cies ; such are the different intellectual and moral peculiarities which affect certain women. The countenance becomes much altered from the absorption of fat, the eyes, look somewhat sunken, and surrounded with a dark areola, the alae of the nose are pinched, and the corner of the mouth dragged down, and the mouth hence looks larger. The blood is said to be buffy; but Dr. Montgomery suggests that this may be, because those women who have been bled whilst pregnant, have been so bled on account of some inflammatory disease; and he alto- gether denies that any indications of pregnancy can be derived from the blood. Dr. Garrod has stated that the proportion of fibrin is not increased in the blood of pregnant woman. Lecat mentions a woman, whose face became black in three successive pregnancies, and Gardien relates other instances. Burns men- tions discoloration of the skin as not infrequent, and some women always have some cutaneous eruption during utero-gestation ; others have dark spots developed upon the face. [I have had two patients who had a marked change in the color of the hair during each pregnancy; it becoming two or three shades lighter so as to be very noticeable both by herself and friends. One of these ladies supposed herself a second time pregnant from this alteration coming on when suffering from a 6evere ulceration of the cervix uteri, accompanid by hypertrophy of the whole organ, gastric disturbance, pain in the mammae, and all the usual symptoms of pregnancy except the suppression of the menses, which were, however, only diminished in quantity. With returning health the natural color^was restored.] Intense pulsating occipital headache has been considered a sign of pregnancy by Dr. Beccaria, and hence called Beccaria's 148 OCCASIONAL SIGNS OF PREGNANCY. % test. Pruritus is with some women a very constant indication of the commencement of pregnancy. Jacquemin and Kluge called attention to a violet color of the vagina and inner surface of the vulva as an indication that the uterus was tenanted. Parent Duchatelet corroborates these state- ments, and says the color is never absent in pregnancy. Pres- sure from any other cause, obstructing venous return from the parts, would have the same effect; hepatic disease, or pelvic tumours, or obstructed respiration, may be attended by a similar discoloration. Osiander attached some importance to the vagi- nal pulse, which may be felt somewhat increased in volume and force as pregnancy advances. The vaginal artery, he says, can be felt pulsating more rapidly than the radial when abortion is threatening. LECTURE IX. DISORDERS OF PREGNANCY. Gentlemen :—The special disorders of the pregnant state chiefly arise from sympathetic irritation of other organs by the uterus and its contents; from morbid conditions of the gravid uterus itself; from the effects of mechanical pressure and dis- placement ; and from the influence of these causes, combined with the modifications of nutrition and excretion incidental to the development of the foetus and the suspension of the catamenial function, upon the maternal vascular and nervous systems. In the production of many of the affections of pregnancy, all these causes more or less occur ; and some of the prominent disorders are but the signs of pregnancy in an exaggerated form. Too much attention cannot be given by the student and practitioner to the diseases of the pregnant state, and to the prudent manage- ment of pregnancy. It is during gestation that the foundations are laid for some of the most dangerous affections of labor and the puerperal state. Pregnancy is the time for prophylactic mea- sures, having reference to the safety of the mother and child in parturition. Conjunctures frequently occur, in which no amount of care and skill at the time of labor can make up for apparently trivial neglects during the course of gestation. This is the espe- cial period when difficulties may be foreseen, aud prevented or avoided. Nothing will contribute more to the reduction of the dangers and mortality of obstetric practice than a careful atten- tion to the disorders of pregnancy. Of the disorders depending upon sympathetic irritation, excessive Nausea and Vomiting are amongst the most troublesome to which the pregnant woman is liable. Sometimes the affection is bearable, the stomach returning certain kinds of food, or being irritable only at particular times of the day, espe- cially in the morning. In other cases, it continues to such an 140 150 the vomiting of tregnancy. extent that constant nausea distresses the patient, and vomiting invariably follows upon every attempt to take nourishment, whether in the liquid or solid form. The epigastrium becomes tender, and there is general fever, with great prostration and debility as in idiopathic gastritis. An almost poisonous influ- ence seems to be exerted by the gravid uterus in some constitu- tions. Such a state of things may go on for weeks or even months, and it is difficult to account for the continuance of life in some of these cases, except upon the supposition that a small quantity of food remains in the stomach after each vomiting. It occasionally happens that other circumstances besides the uterine irritation increase the tendency to vomiting: women, for instance, who have undertaken voyages during pregnancy, have died from the combined effects of sea-sickness and the vomiting of pregnancy. A friend of my own lost a sister from this kind of vomiting, during a voyage to Australia. I have known of two other similar instances, and such cases are not very uncommon. I have seen the gastric irritation much aggravated by the concurrence of hooping-cough during the gravid state. In the worst cases, women who are not relieved, or who do not abort, perish slowly from starvation, or they die from the rup- ture of a bloodvessel, convulsions, or exhaustion, after violent and continued fits of vomiting. The matters vomited from the stomach consist of the food and drink swallowed, an acid, glairy, or watery mucus, secreted by the stomach and pancreas, and, when the sickness is excessive, of bile which has ascended into the stomach by an anti-peristaltic action, or of blood from rup- ture of vessels during paroxysms of vomiting. The first thing to be attended to, as regards treatment in the vomiting of pregnancy, is to attempt to get the secretions, parti- cularly those of the stomach and bowels, in as healthy a state as possible. One of the most old-fashioned and serviceable reme- dies is the infusion of calumbo with soda, The calumbo and soda, with from three to five drop doses of the dilute hydrocy- anic acid, three times a day, is a very useful combination. A grateful and sedative tonic is also made by giving citric acid with the calumbo and soda, so as to form an effervescing draught. Cases are met with in which vomiting affords great relief, by getting rid of vicious gastric secretions, and contributing to re- store the stomach to a healthy state; such patients should be REMEDIES for pregnant vomiting. 151 puked occasionally with warm wrater, camomile tea, or a mus- tard emetic. In some patients, the stomach retains food after taking moderate doses of opium and morphia, and perhaps the solution of the bimeconate of morphia is one of the best forms in which an opiate can be given. Salicine, in doses of three to five grains, three times a day, is a valuable medicine, which was first mentioned to me by a medical practitioner. It allays sickness, and promotes appetite and digestion. Kreasote, in one or two drop doses, made in pills, with crumbs of bread, is well known as an efficient remedy in this affection. Professor Simp- son strongly recommends the salts of cerium, particularly the nitrate of cerium, in doses of one to two grains in water. Dr. Simpson has also used the vapor of laudanum as an inhalation with good effect. [Chloroform, ten drops in mucilage or syrup taken every two or three hours, or by inhalation, is sometimes effectual in arresting it; also Hydrocyanic, acid in some form. The infusion of the bark of the wild cherry frequently gives speedy relief. Water without syrup, impregnated with carbonic acid gas, known as plain soda water, taken by the wine-glass full, cham- pagne and brisk bottled cider are very grateful and not unfre- quently entirely relieve this very distressing and often danger- ous symptom.] Where there is tenderness of the epigastrium, with fever, and an active state of the circulation, a few leeches may be applied to the pit of the stomach, or a small bleeding from the arm may be practised with good effect. Counter-irritation, in the shape of sinapisms, the turpentine stupe, or blistering, will sometimes afford great relief. In some cases, the stomach is soothed by the application of warm poultices sprinkled with laudanum, or a pledget of lint dipped in laudanum, the epigastrium having first been stimulated by a mustard plaster. The recumbent pos- ition, and perfect quiet, is of great use in the worst of cases. It is sometimes necessary to treat not. only the sickness, but also the Marasmus which is the result of excessive vomiting. A daily warm bath is a great comfort to such patients, and in cases of excessive prostration, gelatinous matter may be added to the bath, with a view to the endermic absorption of nutriment. Beef-tea injections, and the inunction of cod-liver oil, or sperm or salad oil, are very useful. I have seen a patient suffering from Vy2 INDIGESTION AND HEARTBURN. incessant vomiting, in a state of great anaemia, with oedema of the lower extremities from pure debility, kept up in the latter part of pregnancy, mainly, as I believe, by the daily inunction of cod-liver oil over the abdominal surface. When all other means fail, and when the exhaustion of the patient cannot be arrested, the remedy is the emptying of the uterus, and this should never be delayed so long as to put the patient in a state of imminent peril. Nature herself often terminates the distress by spontaneous abortion. It has happened to me to have been twice consulted within a recent period in cases in which the in- duction of premature labor artificially was so long delayed, that the patient died before abortion could be induced. Paul Dubois has stated that he met with twenty fatal cases in thirteen years. It is a reproach to our art that such cases should occur. The means of inducing abortion and premature labor will be dis- cussed hereafter. Anorexia, Indigestion, Heartburn, Gastralgia, and Variable Appetite, are caused in certain patients by the reflected irrita- tion of the gravid uterus upon the stomach. Some women never feed so well as when they are pregnant, but in general, the appetite fails somewhat, and particular articles of food are re- garded with aversion. A morbid desire for salted matters, acids, or alkalies, is not uncommon. Sometimes there is great loathing of every kind of food, or there is an extravagant desire to eat particular things, amounting to pica. These longings, as they are termed, should be gratified as far as they reasonably can be. The common tendency of the appetite in pregnancy is to prefer fresh vegetables, fruits, and cooling drinks, and to avoid stimuli of all kinds. In this, the taste of pregnancy accords very well with its requirements. When the appetite is unnatural, the state of the bowels should be carefully regulated, and the patient kept as far as possible from taking things likely to be absolutely hurtful, as convulsions before and during labor are sometimes caused by the habit of indulging in improper and indigestible kinds of food. The remedies serviceable in exces- sive vomiting are also useful in the gastric disturbances now under consideration. Soda and magnesia are the best antacids' in heartburn. In the neuralgic state of the stomach, which occasionally obtains, bismuth, hydrocyanic acid, kreasote or an opiate plaster to the epigastrium, are useful. Sometimes small VARIOUS DISORDERS OF PREGNANCY. 153 doses of acetic acid, or the mineral acids, will relieve the stomach in a re narkable manner; and when the neuralgia re- curs at a particular hour of the day, it is generally relieved by quinine. In certain cases, uterine irritation excites the bowels to increased action, and tenesmus and diarrhoea are the results. In such cases, astringents should be given sparingly, unless the diarrhoea should be so considerable as to produce debility or lead to the risk of abortion. Care should, in the first instance, be taken to render the secretions as healthy as possible, and to avoid articles of diet likely to irritate the bowels. If necessary, the purging should be arrested by an opiate, with compound chalk mixture, bismuth, or gallic acid. When the diarrhoea depends, as it sometimes does, upon faecal accumulation, or vicious secretions, a brisk purgative is the best remedy. Facial Neuralgia from uterine irritation is a very common affection of pregnancy. It generally affects the dental nerves, particularly those of the upper jaw. In many subjects, acute caries of the teeth occurs; and in some child-bearing women, a tooth or two is lost in each pregnancy. In neuralgia of the face, with or without disease of the teeth, a generous diet is called for, with wine and porter. Quinine and the lighter pre- parations of iron are very useful in such cases. Cold and damp. and residence near a river, or the neighborhood of any large body of water, should be avoided as much as possible. Teeth ought only to be extracted with caution during pregnancy under such circumstances. The local application of chloroform, kreasote, camphorated spirit, nitric acid saturated with camphor, and other anodynes, scarification, or the application of a leech to the gum, are the best means of alleviating the pain. A painful state of the Mammae sometimes occurs during preg- nancy, but seldom requires anything more than frictions, with an anodyne liniment or warm fomentations. Occasionally, however, acute Mammitis occurs from the irritation of preg- nancy, requiring leeching and other active treatment. One of the most remarkable sympathetic disorders of pregnancy is the occurrence of Goitre to a slight extent. The treatment of this enlargement of the thyroid is not of much avail during gestation, and the goitre generally disappears after parturition. Allied to this affection is the excessive Salivation which occasionally hap- pens in pregnant women, leading to no serious results, and gen- 154 DROPSIES OF PREGNANCY. erally requiring no further treatment than the use of an astrin- gent wash to the mouth. We shall have presently to cousider the cedematous states of the lower extremities, depending upon pressure and debility ; but there is another form of dropsy incidental to pregnancy, affecting not only the limbs, but the cellular tissue of the body generally : this is the (Edema Gravidarum of the older authors. No other cause than pressure on the vessels was, I believe, known for such a state of things until Dr. Lever pointed out its connec- tion with albuminuria. Other observers have added to this valuable advance in pathology, and it is now a well recognized fact that pregnant women, especially' primipara, are often the subjects of Albuminuria, resulting in local and general dropsy, and involving, unless relieved, very grave dangers at the time of parturition. Albuminuria was first pointed out by Dr. Lever and Professor Simpson in 1843, in connection with puerperal con- vulsions, but since that date more attention has been paid to this condition at the time of labor than during its early stages in pregnancy. This is a misfortune, inasmuch as little can be done in such cases at the time of parturition, while if detected early, the disorder can be relieved in the great majority of cases. It has been said that this disorder cannot be arrested during preg- nancy ; but I have never met with a case that resisted treatment, unless it had been neglected until towards the close of gestation. The cause of albuminuria of pregnancy has been considered to be the pressure of the gravid uterus. It has been found that ligatures applied to the renal veins will produce albuminaria artificially. Its prevalence in first pregnancies, when the abdo- minal walls are more tense than in multipara; in twin cases; and in subjects affected with dropsy of the amnion; and its rapid disappearance after labor, in most cases, seem to favor this view. Probably pressure on the kidneys is one cause of albuminuria; but I have seen it occur in primiparous women of relaxed habits as early as the fourth or fifth month, where the abdominal walls were flaccid, and no apparent pressure or ten- sion existed. The disease appears to me in such cases to depend upon sympathetic irritation of the kidneys by the gravid uterus, similar with the irritation of the salivary glands, .the mammae, thyroid, etc., and not upon mere pressure. It certainly has not the same tendency to occur in ovarian dropsy, or in large EFFECTS OF ALBUMINURIA. 155 fibrous tumors of the uterus, in which the pressure may be quite as great, and sometimes as rapidly induced, as in pregnancy. According to the researches of M. Blot and Professor Litzmann, albuminuria is not a very uncommom affection in pregnancy. M. Blot found it in about twenty per cent, of the women he exam- ined, and Dr. Litzmann in a somewhat larger proportion. It is found, as already stated, more frequently inprimiparathan in mul- tipara. Probably when the albumen is in small quantity no spe- cial symptoms result. When the amount of albumen is excessive, and the disorder has proceeded without check, we have the legs enormously swollen, and the vulva and vagina become so tumid as to render an examination very difficult. There is puffin ess of the face and hands, oedema of the abdominal walls, and almost every part of the body pits deeply upon pressure. The patient complains of headache, and sometimes dimness of sight and amaurosis. Lumbar pain is frequently present, and there is general pyrexia. The urine is small in quantity, and nearly solidifies upon the application of heat and nitric acid. It is gen- erally of high specific gravity, loaded with phosphates, fre- quently alkaline- in character, and containing epithelium or fibrinous casts of the tubuli uriniferi. Besides the loss of albu- men, urea is retained in the blood, and appears to have been detected in this fluid as such by Dr. Lever. Other observers have failed to find urea. According to the view of Frerichs and Litzmann, urea becomes converted into ammonia, which has been found in the blood and in the secretions of the skin and lungs of albuminurious patients. As the poisoning of the cir- culation by urea and the loss of the albuminous portion of the blood proceeds, an intense degree of anaemia is induced. It is of great importance to relieve such a state of things before the corning on of labor, as albuminuria predisposes powerfully to convulsions and phrenitis, and according to my experience, to dangerous haemorrhage during and after labor. The treatment consists in small bleedings where there is distinct lumbar pain and general and febrile excitement, or cupping upon the loins, or counter-irritation by sinapism, in the same situation. Warm baths and vapor baths are often very useful in restoring the function of the skin, removing the effused fluid, and disposing the kidneys to act. I have also found the use of diuretics, as the acetate of potash, oil of juniper, and infusion of broom, most 156 TREATMENT OF ALBUMINURIA. useful. Frerichs and Litzmann have given benzoic and citric acids, with a view to remove the ammonia from the blood, and it is said with good effect. When there are no signs of renal inflammation or congestion, and the quantity of albumen has diminished, and that of the urine increased, a generous diet and the administration of iron and tonics should be resorted to, in order to repair, as far as possible, the weak condition of the blood which has been produced. The detection and treatment of albuminuria in pregnancy is one of the points of progress deserving the special notice of all engaged in the practice of midwifery. I have no doubt the rate of obstetric mortality may be sensibly diminished by attention to this subject. The urine should invariably be tested for albumen in all cases of oedema of the extremities. I am not aware that the matter has been observed by obste- tric authors, but in some pregnant women the urine, without being albuminous, contains habitually a large quantity of triple phosphates, is of high specific gravity, and has an alkaline reaction during the greater part of pregnancy. The nervous and vascular erethism attendant upon, or produced by, the state of pregnancy, is followed by the same results as other and more marked causes of exhaustion. I have known this Phosphatic Diathesis to exist in cases in which fatty degeneration of the placenta has occurred in successive pregnancies. In one lady who had given birth to eight dead children at or near the full time, this state of the urine was very marked. The death of the children occurred before the end of gestation from placen- tal disease, and was caused by the separation of the placenta before the occurrence of uterine action ; or its attachment was so slight that it was separated by the first contractions of the uterus ; or the children were born in such a weak condition that they died soon after birth, leaving the foetus to die of asphyxia. The treatment in such cases should be that employed in the phosphatic diathesis occurring under other circumstances than pregnancy—namely, the mineral acids, opiates, rest, and a nutri- tious regimen. Such patients also require, either during or after the completion of pregnancy, preparations of steel, as a marked degree of anaemia is produced by the persistence of the dis- order. Some gravid women experience great distress durino- preo-- HEADACHE OF PREGNANCY. 157 nancy from the sympathetic irritation of the Heart, palpitation occurring upon the slightest exertion or emotional disturbance ; in others, the respiration is similarly affected, and attacks of dyspnoea, approaching to asthma, harass the patient. These affections are aggravated as pregnancy proceeds; and the effects of mechanical pressure upon the heart and lungs by the ascent of the diaphragm, and upon the great vessels in the abdomen, become added to those of sympathetic irritation. In such cases an opium or belladona plaster over the heart, and use of anti- spasmodics, such as sulphuric or chloric ether, valerian, musk, and similar remedies, are useful. Every means should also be taken to diminish, as far as possible, the effects of mechanical pressure. Cough is very troublesome in some cases. At the commencement of pregnancy, the cough may be spasmodic, and caused by sympathetic irritation of the throat and glottis ; and, in the later months, by the upward pressure of the gravid uterus upon the diaphragm and lungs, a condition often accom- panied by pleurodynia. In the former case, the cough is soothed by opiates and a good diet; in the latter, nothing can be done beyond obviating the effects of pressure as much as pos- sible, by attention to the bowels, and the position of the patient. Such patients, for instance, require to sleep with their heads raised, and very great comfort is often obtained by the use of small air-pillows, which can be shifted about with ease by the patient. Cephalalgia and Cerebral Irritation are sometimes produced by the irritation of the gravid uterus. They are, however, more frequently the secondary result of some other disorder incident to pregnancy. Thus, headache occurs as a symptom of albuminuria, constipation, anaemia, indigestion, etc. When it is caused directly by the condition of the uterus, it should be relieved by cooling applications, as ice or a spirit lotion, to the head, and a few leeches to the temples, small blisters behind the ears, aperients, etc. When headache is only a symptom of some other condition arising out of pregnancy, the treatment must be modified according to the particular disorder upon which it depends—as, for instance, a purgative in constipation ; quinine or iron in anaemia ; albuminuria, the treatment adapted for the relief of this condition, and so forth. Severe headache is a 6ymptom which should always attract the attention of the 15S VARICOSE VEINS OF PREGNANCY. accoucheur, since we know that it may be the possible forerun- ner of puerperal convulsions or mania. It occasionally happens that actual mania has been caused by the irritation of preg- nancy, and apoplexy, epilepsy, and chorea have been met with. In these severe complications, the only efficient treat- ment consists in the artificial evacuation of the contents of the uterus. Having referred to the principal forms of disorders depen- dent upon sympathetic nervous irritation, we come to the consi- deration of those caused chiefly by the pressure of the gravid uterus. Amongst the most obvious results of pressure are the impediments to the circulation in the lower extremities. The weight upon the external iliac veins, particularly in the upright position, very commonly causes a varicose state of the veins of the legs. This condition is most aggravated towards the end of pregnancy, and in women who have borne large families, or who have been obliged to exert themselves during gestation, the varicose veins sometimes inflame at particular points, or throughout a considerable extent, and the walls of the veins may become thin and burst, giving rise to dangerous haemor- rhage. In other cases, varicose ulcers are formed by the inflam- mation and suppuration of a patch of varicose veins. Certain inconveniences also arise as the result of pressure on the inter- nal iliac veins. In the latter months of pregnancy, the disten- sion of the internal iliac veins is caused by the pressure of the gravid uterus upon the common iliacs ; mit in the early months the pressure is exerted directly upon the internal iliac vessels by the expanding uterus before it has yet emerged from the pelvis. In this way, haemorrhoids, congestion, and varicosity of the vagina, and a varicose state of the vulva, are caused. In the latter condition, effusion of blood may take place from the veins into the cellular tissue, constituting thrombus, which sometimes attains a considerable size, and proves an impediment at the time of labor. Haemorrhoidal discharges are not uncommon in the early months of pregnancy from this cause, and, in some habits, blood is lost from the haemorrhoidal vessels for the first monthly period or two after the commencement of pregnancy. Similar disordered conditions of the pelvic veins may after- wards be caused by pressure upon the common iliac. Proba- bly the effects of pressure have some influence in causing a pie- CEDEMA OF LIMBS. 159 thoric state of the uterus itself ; but as the uterine veins empty themselves partly into the internal iliac, and partly into the inferior cava and renal veins, the early gravid uterus is to a considerable extent defended against the consequences of pres- sure. In the management of these conditions, as in all the disorders of pregnancy, it must be remembered that except in the last resort, the cause of disorder cannot be removed, and that we can only deal in palliative measures. The varicose state of the veins of the lower extremities may be relieved by rest in the recumbent position, and by wearing a roller, or an elastic stocking. In the event of a varicose vein bursting, the patient ought to be laid down, and placed, with her legs raised above the level of the head, until the bleeding has ceased, and pressure should be applied to the ruptured vein. The distension of the haemor- rhoidal and vaginal veins may be relieved by rest, and the avoidance of constipation ; and if the veins of the vulva are varicosed, by the pressure of an elastic bandage applied to the part. The pressure of the gravid uterus upon the lymphatics in the pelvis sometimes gives rise to simple (Edema of the lower extremities, in cases where no disturbance is caused by venous pressure. At others there is oedematous enlargement of the feet and ankles, combined with a varicose state of the veins. The oedema is aggravated by standing or walking, and becomes worse every evening, particularly as pregnancy advances. It is generally relieved by rest in the horizontal position, or, if painful, by an opiate embrocation. It disappears very soon after the occurrence of parturition. Cramp in the leg is a very ♦ troublesome affection to some pregnant women, and in subjects in whom it occurs during gestation the disorder occasionally amounts to intense and continued agony during labor, affecting the muscles of the abdomen as well as those of the lower extre- mities. It depends partly on the pressure upon the lumbo- sacral nerves in the pelvis, and partly on the irritation of the gravid uterus, or constipated bowel, reflected upon the nerves of the lower extremities, apart from mere pressure. The ten- dency to cramp is increased by unusual exercise, long standing in the upright position, or by the omission of accustomed exer- cise. The treatment consists in friction and extension of the 160 INCONTINENCE OF URINE. limbs during the paroxysm, and the avoidance, as far as possi- ble, of the causes of this painful aftection—that is, the bowels should be kept regular, and rest and exercise should be attended to in due moderation. Constipation is prone to occur in preg- nancy, partly because of the mechanical pressure exerted on the rectum, and partly because the state of the gravid uterus acts as a contra-stimulant to the intestinal canal. Sulphur, bitartrate of potash, manna, or the lenitive electuary, should be given in cases of constipation, when the bowels are readily moved. In more obstinate cases, castor oil, or the compound rhubarb pill, or an injection of soap-and-water, are useful. There is a very common prejudice in favor of aloes, and this medicine is well suited to cases in which the derivative influ- ence of the gravid uterus has reduced the rectum to a state of torpor. Its effects, however, should be kept within .certain lim- its, otherwise it is apt to excite the uterus. Magnesia should be avoided as a purgative during pregnancy, and it should not be used to any great extent as a means of relieving heartburn, on account of its tendency to accumulate in the rectum. Serious complications may occur at the time of labor, or subsequently, from neglect of the bowels, or from habitual constipation during the pregnant state. This is particularly the case with women who have required opiates during pregnancy, in whom accumu- lations of faecal matter in the colon are very apt to occur. There may be a daily partial action of the bowels in such cases, but the bowels may become so loaded notwithstanding, as to complicate, favor, and tend to the production of fever or convul- sions after parturition. Strangury and incontinence of urine are often met with in pregnancy; in the early months, from irritation of the bladder, the irritation being partly caused by pressure, and partly reflected from the gravid uterus; and in the latter months, chiefly as the result of pressure. Little can be done in such cases beyond enjoining rest, giving an opiate—particularly when the affection occurs in the early months—and taking care that the urinary secretion is kept in as healthy a state as possible. The distension of the diaphragm and abdominal muscles by the gravid uterus is occasionally the source of severe pain in these muscles. This muscular pain may be felt especially in the dia- phragm, in the situation of its insertion into the ribs in the HERNIA INTO THE LABIA. 161 course of the rectus, or in the bellies of the oblique muscles. It is relieved by an occasional warm bath, the use of frictions with olive oil to the abdominal surface, an anodyne embrocation, and especially by wearing a suitable bandage, so as to support the strained muscles. I have sometimes seen these pains, after bleeding and leeching had been tried in vain, relieved at once by the use of a well adjusted bandage. Occasionally the skin is the seat of great uneasiness from the distension of the abdomen becoming cracked, and oozing out a watery secretion. The best relief for this state is the use of oleaginous frictions, an occa- sional warm bath, and the support of the abdominal bandage. [Hernia sometimes accompanies pregnancy, the intestine coming down by the side of the vagina and filling the labium so as to greatly enlarge it. It is rarely a very serious complication, but it is sometimes a cause of much anxiety to the patient. Occa- sion should be taken to restore it by making gentle pressure while the woman lies upon her back. If kept up for a few days or weeks it will rarely reappear. It is generally the result of a strain in lifting.] 11 LECTURE X. DISORDERS OF PREGNANCY. Gentlemen :—In the last lecture, reference was made to the disorders of pregnancy depending upon sympathetic Irritation and Mechanical Pressure; and we now come to the considera- tion of displacements of the Gravid Uterus, and their effects. Conception may, and does occur in women suffering from Pro- lapsus or Procidentia, as in cases where the uterus is occasionally reposited, or returns of itself when the patient is in the recum- bent position. Under such circumstances, there may be pro- lapsus or procidentia of the pregnant uterus in the early months. Harvey mentions a case of this kind. Unless abortion should happen while the uterus hangs externally, no other evils but the discomfort of such a state of things and the risk of abortion are usually experienced. After a while, the uterus no longer descends, the ovum acting as a very efficient intra-uterine pes- sary. All that is required in the way of treatment is the return of the uterus within the vagina by gentle pressure, and the con- tinuance in the recumbent position for a time. Occasionally, however, where the uterus has formed adhesions, abortion is caused, or inflammation and pelvic abscess is the result. In women who have borne many children, or who are of relaxed habits, or in whom large umbilical hernia exists, the uterus in the latter months of pregnancy hangs over the pubes constituting Anteversion of the gravid uterus. Occasionally, in these cases, considerable disturbance of the bladder is expe- rienced in consequence of the dragging and pressure exerted upon the neck of the organ. When the anteversion is consider- able, the bladder is drawn upwards to a considerable extent; the unwieldy condition of the patient interferes very much with progression ; and the loss of the proper axis of the uterus, and the impeded action of the abdominal muscles, become impedi- 162 THE UTERUS DISPLACED. 163 ments to parturition. In the first month or two of pregnancy, the natural position of the uterus is, as already mentioned, a slight anteversion of the organ, as compared with the axis pre- served in the ungravid state, and the body of the organ can be felt in front of the os uteri, and between the os and the pubes. This generally produces no other inconvenience save that of pressure on the bladder; but when the anteversion is very marked, as when a womb already anteverted becomes impreg- nated, or when large accumulations in the rectum takes place, the vesical irritation and disturbance becomes more distressing. In the early months, the patient should be a good deal on her back, and the rectum should be emptied daily by an enema or some mild aperient. The treatment of anteversion in the latter months consists of rest in the supine position, and the use of a proper bandage. By far the most formidable displacement to which the gravid uterus is liable is Retroversion—an affection noticed by Daven- ter and some of the early obstetricians, but first observed dis- tinctly by Gregoire, and fully described by William Hunter and Denman. This affection occurs in its most decided form at about the third or fourth month, when the uterus is entirely within the pelvis, and when it is of such large size that any alteration from the natural position occasions great inconveni- ence to the neighboring organs. It is usually described as arising from excessive distension of the bladder, through neglect, reserve, or restraint on the part of the patient. It is believed that the full bladder, rising in the abdomen, drags the neck of the uterus upwards, while the bulk of the distended organ presses the fundus uteri backwards. The displaced uterus, by the pressure it exerts upon the neck of the bladder, in turn increases the distension of this viscus, and the retroverted uterus at length becomes fixed across the pelvis, the fundus lying in the hollow of the sacrum, and the os being- tilted against the pubes, so as, in the worst cases, to render the evacuation of the rectum difficult, and the bladder impossible. This explanation of the matter, which has been implicitly followed by almost all writers on midwifery, was current, it should be observed, long before the subject of retroversion of the unimpregnated uterus came to be understood. My own observation inclines me to give a different view of the mode in which retroversion of the 164 RETROVERSION FROM DISTENDED BLADDER. gravid uterus may occur—a view illustrated by a case which recently fell under my care. A lady in whom the symptoms of retroversion of the uterus had existed for some years before her marriage, became pregnant, and the inconveniences from which she had suffered immediately became aggravated. I examined her when she had been pregnant about ten weeks, and found the uterus completely retroverted. The fundus was almost pressing upon the perinaeum, and the os uteri could be felt high up in front, behind the pubes. At this- period there was no sensible pressure on the bladder; the organ could be readily emptied, and the urine was retained the ordinary time. It was upon the rectum that the pressure was chiefly felt. The uterus did not lie horizontally in the pelvis in the usual way described, but the organ was bent upon itself at the cervix, just as a retort is bent at its neck. As the case went on, and the uterus occupied the greater part of the pelvis, pressure on the bladder became pain- ful, and I have little doubt the worst symptoms of retroversion would have occurred, had not care been taken to keep the blad- der and rectum comparatively empty. The leverage of increased growth, aided by attention to the bladder and rectum, gradually raised the fundus uteri, and as the organ emerged from the pel- vis it assumed the proper position. Without question, retrover- sion of the gravid uterus may be caused by an over-distended bladder, but I suspect that many cases of retroversion occur in the way I have described—from impregnation of the uterus already retroverted. At first, no great inconvenience is felt, but there comes a time when the os uteri presses on the bladder and prevents its evacuation. Then ensue the symptoms of retrover- sion, and that which has occurred slowly is looked upon as a sudden displacement. I have seen other cases in which preg- nancy happened in patients suffering from retroversion, and sometimes retroversion has occurred in successive pregnancies in the same subject. It is believed that a pelvis above or below the average size, or narrower at the brim than at the outlet, may predispose to this affection. The symptoms of retroversion, when the uterus is of such dimensions as to exert mechanical pressure upon the antero-pos- terior walls of the pelvis, are, in the first instance, partial or complete retention of the urine, pain in the pelvic region and a sense of pressure on the rectum, giving rise to the constant TREATMENT OF UTERINE DISPLACEMENT. 165 desire for defecation, even when the bowels are empty. Should these symptoms pass unrelieved, the bladder becomes enor- mously distended, and it is sometimes ruptured mechanically, or its coats inflame and ulcerate, allowing the urine to escape into the peritoneal cavity, and the patient sinks or dies of peritonitis. If the uterus cannot be replaced, and the water is occasionally and with difficulty drawn off, the bladder gradually enlarges and elongates, and its mucous membrane diseased : muco-pnru- lent, ammoniacal, and bloody urine is passed, and the kidneys may become diseased by the effects of the backward pressure of the urine. The structures between the bladder and the uterus may become inflamed, and the patient be destroyed by irritative fever. In some cases all these mischiefs are averted or modified by the occurrence of spontaneous abortion. In others the dis- placement continues to the fifth or sixth month, without destroy- ing the patient, and it has been known to go on to the full term without causing a fatal result. As regards treatment, the first thing to be done is to obviate as far as possible the effects of pressure, by catheterizing the bladder and emptying the bowels by aperients or enemata. In some cases, these means, and directing the patient to empty the bladder frequently, and the bowels daily, are so efficient that no further inconvenience is felt, and the uterus rises into the abdo- men as pregnancy advances. When the pressure cannot be relieved by these means, an attempt should be made to raise the fundus uteri mechanically. This should be done by introducing the fore-finger of one hand into the vagina, and the fore-finger of the other into the rectum, when the os should be drawn down with one finger on the uterine sound, and the fundus elevated with the other. The most convenient position for the patient during these manipulations is on her knees in bed, with her head lowered. M. Gariel has proposed that one of his vul- canized india-rubber pessaries should be introduced into the rectum, or into the vagina, and that the fundus uteri should be raised in inflating the pessary. I do not know if this plan has been tried in practice, but it would probably be effec- tive in a case admitting of the mechanical re-adjustment of the uterus. When the uterus was firmly wedged in, it might, how- ever, unless great caution were observed, lacerate the soft parts. If the symptoms are so serious as to threaten the safety of the 166 INSTRUMENT FOR REPLACING RETROVERSION OF THE UTERUS. mother, and the reduction of the retroversion cannot be affected, the uterus should, if possible, be emptied of its contents, by pass- ing the uterine sound or a curved bougie into its cavity, and either rupturing the membranes, or detaching the ovum. We have seen that Nature itself sometimes gets rid of the difficulty by abortion. If the uterus cannot be emptied in this way, it should be punctured from the vagina or the rectum. These operations have been successfully performed, but they should of course, only be resorted to in dangerous cases, and when there is no time for the induction of abortion. Fia. 49. The action of M. Gariel's instrument for replacing the retro- verted uterus, is shown in Figs. 49 and 50. The instrument itself consists of a dilatable air pessary terminating in a tube, and an air reservoir, with small taps affixed to each. After im- mersion in warm water, the collapsed pessary is passed into the rectum, behind the uterus, by means of a probe. The air reser- voir is then fitted to the tube of the pessary, the taps are opened, and by the pressure of the hand, the air contained in the reser- voir is transferred to the pessary, so as to lift the uterus out of RELIEF OF RETROVERSION. 167 the hollow of the sacrum. This instrument is made by Mr. Hux- ley, of Old Cavendish street. Fig. 50. Dr. Henry Bond, of Philadelphia, has invented an instrument for the relief of retroversion, which Dr. Meigs states was suc- cessful in a difficult case which had resisted other means. The following is the description of this instrument, as given by Dr. Meigs (see Fig. 51): " The instrument consists of two arcs of circles of different radii; the inner one is terminated by a small oval piece of ivory; the outer terminates in a small ivory ball. The exterior arc is formed at its lower extremity into a plate-piece, in which is a mortise; to the end of the plate-piece is attached an ivory handle, by which it may be conveniently held. The inner or smaller piece is attached to a sliding piece, also mortised, and overlapping by its edges the mortised plate-piece, and secured by a clamp or pinch traversing the mortises, and fastened or loosened by turning the thumb-piece. If the thumb-piece be unscrewed, the clamp may be turned lengthwise, and the arcs are then easily separated. In order to use the instrument, the arcs should first be separated, and the ivory ball on the largest arc introduced into the rectum, while the oval one on the smaller 168 DISORDERS OF PREGNANCY. arc should be introduced into the vagina. By sliding the smaller arc upwards, the two balls can be placed opposite to each other; or the vaginal arc can be set a quarter of an inch, a half inch, or an inch lower down than the one that is in the rectum. Upon being adjusted and firmly secured by turning the thumb-piece, it is manifest that the two balls cannot be separated from each other, and that if they be moved upwards, parallel with the curve of the sacrum to the height of the pro- montorium, they must carry the retroverted uterus before them, and thus serve very effectually and easily to reposit the dislo- cated organ." The disorders of pregnancy depending upon the uterus and vagina are, Uterine Plethora, Hysteralgia, a painful condition of the Round Ligaments, Pruritus, Sanguineous Discharges, and Leucorrhcea. Uterine Plethora in the early part of pregnancy, as the joint result of pressure and the determination of blood to the uterus in the processes of nutrition, may exist to such an extent as to cause bearing-down, heat and pain in the back, and a sense of pelvic fullness, with inability to walk—symptoms which, if not relieved, are pretty sure to produce abortion. On examination per vaginam, the canal is found hot and dry ; the uterus is RHEUMATISM OF PREGNANCY. 169 swollen, low down in the vagina, and rigid and painful to the touch. This condition should be treated by the avoidance of intercourse, absolute rest, aperients of the gentlest kind, or mild enemata, the application of leeches to the perinaeum, or the inside of the thighs, cooling saline medicines, and a light, unstimulating diet. When the uterine pain is considerable, an opiate, or hyoscyamus with camphor, should be given, or an opiate suppository should be introduced into the rectum. Occasionally in the middle and latter months of gestation, the uterus itself becomes the seat of severe pain. If the organ be pressed upon with the hand it is found to be painful, and the movements of the child and the contractions of the uterus itself are accompanied by much suffering. This kind of pain is accompanied by fever, a coated tongue and high colored urine. It is generally considered to be of a rheumatic character, and admits of relief by a light diet, saline aperients, warm baths, Dover's powder, anoydyne embrocations, and liquor potassae, with or without colchicum, according as the rheumatic element may appear to prevail. Some women feel this pain very dis- tinctly in the direction of one or both round ligaments, and I have certainly seen several instances in which rheumatism has appeared to seize upon these ligaments during pregnancy—a cir- cumstance very well explained by their fibrous structure. The treatment would be the same as in rheumatism of the uterus. In both cases every care should be taken to relieve the organ from all strain or pressure as far as possible by rest and recumbency. Pruritus is often met with in pregnancy, and in some women it is so constant as to be a source of much annoyance. It commonly depends on follicular irritation of vthe vulva, which, if unchecked, passes on to aphthous ulceration. Sometimes the vulva is quite free from irritation, and the itching is referred to the surface of the os uteri itself. In either situation, the pruritus is frequently accompanied by sexual excitement. In pruritus of the vulva the secretion from the surface is highly acid. The affection may sometimes be relieved by washing the part with common yellow soap on account of the alkali it contains. Dilute hydro- cyanic acid, Battley's solution, and carbonate of soda, make an excellent wash, in the proportion of one drachm of each of the two former to two drachms of the latter, in six ounces of water. Of this wash, the patient should be directed not to use more 170 ABRASIONS OF THE OS UTERI IN PREGNANCY. than a tablespoonful at a time. A lotion of borax is often very useful. Occasionally, when alkaline applications fail, relief is obtained from an acidulated wash. Sometimes a lotion of tar-water is very soothing in this affection. If the disorder resists these measures, painting the vulva, with a solution of the nitrate of silver, in the proportions of ten grains to an ounce of water, every day or every other day, or with the tincture of iodine mixed with an equal quantity of water, is an excellent remedy. In pruritic irritation of the os uteri, the solution of borax, or of the nitrate of silver, should be used as an injection ; tepid or cold bathing, a cooling diet and occasional aperients are necessary in such cases. It sometimes happens that the pruritus has a periodic character, coming on or becoming aggravated at particular times of the day. In these cases I have seen great benefit from the administration of quinine. Leucorrhoea is a very common affection of pregnancy. The glands of the canal of the cervix share in the increased develop- ment of the uterus, and the secretion which forms the thick plug of mucous closing the cervix uteri is frequently in such excess as to cause a constant discharge. The secretion is thick and perfectly white in color, as it escapes from the os uteri. It is composed entirely of plasma and mucous particles, but in pas- sing through the vagina it becomes mixed with the scaly epithe- lium of the vaginal surface. In some cases, the epithelial covering of the os uteri is abraded to a considerable extent, when muco-purulent or purulent matter is secreted from the abraded surface, and is discharged from the vagina with the mucous of the cervix. Sometimes this abrasion exists before the occurrence of pregnancy, and is only aggravated by the afflux of blood and increased action natural to the gravid uterus. At other times, it originates during pregnancy itself. This subject of the abrasion of the os uteri in pregnancy has been investigated in France by MM. Boys de Loury and Costilhes, and by Dr. Henry Bennet and Dr. Whitehead in this country. The symp- toms consist of purulent or muco-purulent vaginal discharge pain and weight in the lumbar and hypogastric regions all of which are increased by walking or sustained exertion of any kind. Examined by the speculum, the os uteri is seen denuded of epithelium to a greater or less extent, and secreting puriform matter MENSTRUATION OF PREGNANCY. 171 I have ascertained that it is in these cases that the supposed menstruation of pregnancy sometimes occurs. Occasionally large quantities of blood are lost from the abraded surface at each catamenial date. If allowed to pass without treatment, besides the debility induced by the constant puriform discharge, and the occasional loss of blood, there is some danger of abor- tion, or of painful and laborious labor at the full term. In cases of simple mucous leucorrhoea, little is required beyond the use of an astringent injection. [I have given from 3 to 5 grains 172 sums' LEVATOR PERINEI. of the Potasii Ferrocyanuretum dissolved in water three times a day, with much benefit.] In the severer forms of disorder, the treatment should consist of rest, keeping the bowels in a lax state, the use of injections of tannin, alum, the sulphate of zinc, or diacetate of lead, and the occasional local application of the solid nitrate of silver. The application of the nitrate should never be severe, and the employment of the more powerful escharotics should be avoided, lest they should cause abortion. As an astringent, the dilute sulphuric acid, with the compound infusion of roses, or the dilute muriatic acid, may be given. By these means, severe cases of this kind are often cured. It must be confessed that abortion may, and does sometimes occur, from the treatment; and if the use of the nitrate of silver or astringent injections should cause much pain, they ought immediately to be disused. [In the position which the os uteri frequently takes in the early stages of pregnancy it is not unfrequently a matter of no little difficulty to bring the os and cervix into view with any of the ordinary specula. The instrument invented by our distin- quished countryman, Dr. J. Marion Sims—for the purpose of ex- posing the whole of the vaginal walls, as well as the os uteri, will be found in the hypertrophied uterus of pregnancy with the os thrown back into the hollow of the sacrum, to be of great avail. It might perhaps be properly called a levator perinei, for the patient placing herself in the position delineated in the cut an- nexed, as nearly as possible lying upon her breast and stomach, the left arm thrown behind and the chest rotated forward?, bringing the sternum quite in contact with the table or bed, the feet drawn up, one extremity of the instrument is to be inserted into the vulva, and by the other the perineum is to be forcibly lifted up, allowing the pressure of the atmosphere to dilate the vagina, thus giving a full view of the entire vaginal cavity; after a little experience with this instrument, the practitioner will rarely be induced to use the ordinary cone-shaped or even the many valved instruments.] The source of the blood in menstruation, or menorrhagia, dur- ing pregnancy, has often been the subject of discussion. Before the modern views respecting the formation of the decidua, it was difficult or impossible to account for the occurrence of a dis- charge having a menstrual character from the gravid uterus. SOURCE OF MENSTRUAL BLOOD IN PREGNANCY. 173 How could a sanguineous flow issue from the cavity of the uterus when the whole of the internal surface of the organ was occupied by the decidua ? Obstetricians were driven to suppose that the discharge must in such cases be poured out from the cervix, the os uteri, or the vagina. In accordance with the modern ideas respecting the development of the mucous mem- brane of the uterus into the decidua vera, Dr. Matthews Duncan has suggested that the menstrual discharge may be secreted from the decidual lining of the gravid uterus in the early months, before the decidua reflexa comes to be in apposition with the 174 AN.EMIA OF PREGNANCY. decidua vera in its whole extent. According to the view 1 have advanced respecting the loss and renovation of the mucous membrane at the menstrual periods, it is not difficult to conceive that in the first part of pregnancy the lower portion of the decidua vera may become broken down and thrown off with a sanguineous discharge. Probably, in cases of threatened abor- tion, in which there is a colored discharge for several days or a more considerable period, without the loss of the ovum, the lower portion of the decidua vera is destroyed and formed anew. In several cases which have occurred to me, of menstruation during pregnancy, I have, however, found them, on examining with the speculum, to be cases of abrasion of the os uteri. In the in- tervals between the periods the abrasions have secreted pus; but, under the influence of the vascular congestion which occurs at the menstrual dates throughout part or the whole of preg- nancy, they exude blood after the manner of a menstrual ulcer. I met in the course of last year with two cases of this kind. One case I saw with Dr. Sibson and Mr. Johnson, of Kilburn, and in this the periodical hemorrhage was very violent, but it ceased as the abraded surface became healed; the other case, in which a molar pregnancy went on for several months with regular menstruation, the os uteri being abraded, I saw with Mr. Napper, of Cranley, Surrey. Pregnant women are occasionally affected with symptoms similar to those met with in cases of amenorrhcea. In certain constitutions, even while the physiological processes of gestation and lactation are going on, the absence of the stimulus of the catamenial function is felt, and general pallor, oedema of the lower extremities, and other signs of chlorotic anaemia, are the results. I have seen many well-marked cases of this kind. The subject has been slightly adverted to by M. Chailly, and more positively by M. Cazeaux. The same thing may happen, to some extent, during lactation ; and it is my opinion that in many cases of anaemia from undue suckling, the milder preparations of iron, as the ammonio-citrate, are called for, and should be given with a view to remedy the condition of anaemia. It is necessary to bear this tendency of the pregnant woman to anaemia in mind, as it forms a part of many of the other disorders of gestation. This state of anaemia is increased by the vomiting of pregnancy, and by several other disorders of the gravid state. In ordinary DISEASES, HOW INFLUENCED BY PREGNANCY. 175 cases, the last thing wre should do would be to give any prepar- ation of iron, from the fear of inducing abortion; but when the anaemia is marked, the administration of steel tends to the pre- vention of the premature expulsion of the ovum. The influence of pregnancy upon other diseases is an interest- ing subject. It is well known that blood drawn from healthy women during pregnancy generally shows the buffy coat, and it is found that all inflammatory diseases have a tendency to a more acute course than usual, and require a more prompt and active treatment than under any other circumstances. This is particularly the case in inflammatory disease of the chest. Cer- tain diseases are more dangerous during pregnancy than at other times. Small-pox and Scarlatina (also Cholera and Dysenteries) are very fatal, especially the former, from the almost inevitable occurrence of abortion, and the unfavorable condition under which the patient is thus placed. Syphilis is not especially modified by pregnancy; but there is the twofold risk of abortion —from syphilis itself, and from the anti-syphilitic treatment re- quired. There is this peculiarity in the relations of syphilis to pregnancy, that it offers, I believe, an instance in which second- ary syphilis may be transmitted from one constitution to another without the intervention of a primary sore—that is to say, the germ cell receives from the sperm cell of a man laboring under secondary syphilis a dose of the poison, which is, in the first in- stance, developed in the ovum, and imparted to the mother through the medium of the placenta. Some patients suffering from spasmodic asthma are entirely free from the disorder dur- ing pregnancy. All affections of the heart are aggravated by the pregnant state. The progress of phthisis is often remark- ably stayed by gestation; but, after labor, the disease generally goes on at an accelerated pace, and it is not uncommon for women in consumption to die within a few days after parturi- tion. [See on this point the Fiske Prize Fund Essay for 1856, by Ed Warren, M.D. (published by request of the R. I. Med. Soc.) in the Am. Journal of the Med. Science for July, 1857.] Cancer, when affecting the uterus, acquires a considerable impulse from the afflux of blood to the organ, and the develop- ment of the os and cervix uteri, in the latter months of gestation. Epilepsy is, in some cases, entirely arrested by pregnancy, and no puerperal convulsions occur at the time of delivery; in 176 DISEASES AS AFFECTED BY GESTATION. others, the character of the fits is not altered by pregnancy, or they become more violent and frequent, and there is a marked increase in their number at the time of parturition. These points I made out by a pretty extensive investigation a few years since, the results of which were published in The Lancet. The influence of gestation upon mollifies osseum is very marked. This disease, which we shall have to refer to when treating of pelvic deformities, commonly increases with every pregnancy. LECTURE XI. CAUSES OF ABORTION. Gentlemen :—In the last two lectures, certain special disor- ders of pregnancy have been considered. We now come to treat the particular malady to which the gravid woman is liable —namely, the premature loss of the Ovum. It will be seen that many of the other disorders of the pregnant state tend to this catastrophe, and require to be borne in mind in connection with it. Abortion consists in the separation and expulsion of the immature ovum from the uterus. The real adhesion between the ovum and the mother is at the points of connection between the chorion and decidua. At first, this connection is slight. William Hunter stated that in the earlier part of gestation, the chorion and decidua may, by delicate manipulation, be separated from each other without laceration. Afterwards, the intimate connection between the chorion and decidua, and the fusion of the two parts, and of the fcetal and maternal vessels in the pla centa, renders the separation more difficult, and the risk: of abor- tion is consequently diminished. The older accoucheurs paid much attention to the real or supposed loss of the ovum very shortly after impregnation. Married women who passed over a monthly period by a few days, and then menstruated profusely, were believed to have lost the ovum. This was called an Effluxion, if it occurred before the tenth day, " because," as Smellie observes, " the embryo and secundines are not then formed, and nothing but the liquid conception, or genitura, is discharged." In all probability, such cases are not'uncommon, and the ovum is unobserved, not from its liquid condition, but because it is so little above the size of the unimpregnated ovum as not to be visible in the discharges. An ovum of fourteen days has been described by Velpeau, and its size did not exceed the following diagram. In the expulsion 12 m 17S FREQUENCY OF ABORTION. of an ovum of an earlier date than this, the symptoms hardly differ from those of profuse menstruation. For practical purposes, Abortion may be defined as the prema- ture expulsion of the ovum at any time after the ovum becomes visible, and before the twenty-eighth week of pregnancy. Up to the latter date, the foetus is not viable, but after the sixth month, it may with care be reared. There are certain differences requiring notice in abortions occurring before and after the end of the second month, dependent on the different size of the uterus, and the altered development of the vascular connection between the uterus and the ovum, before and after the formation of the placenta. The discharge of the ovum between the end of the second month and the twenty-eighth week, has, in consequence, been termed Miscarriage ; but bearing in mind the peculiarities mentioned, it will be convenient in practice to consider all expulsions of the ovum, previous to the time at which the foetus becomes viable, under the head of Abortion. This termination of pregnancy is exceedingly frequent. Of two thousand pregnant women who applied to the Manchester Lying-in Hospital, Dr. Whitehead ascertained that the collective number of their abortions had amounted to one thousand two hundred and twenty-two. Many of these were yToung women in their first pregnancies, or women who had not completed the child-bearing epoch. As regards the individual results, Dr. Whitehead found that of these two thousand women, thirty-seven out of every one hundred mothers had aborted before they had reached the age of thirty years. The proportion of women who have lived in wedlock until the menstrual decline, to whom abortion occurred, approached ninety per cent. There are, in fact, few women who have passed through the child-bearing epoch, and actually borne children, who have not aborted once or oftener. This is probably one of the subjects open to the greatest improvement in obstetric practice. Considering that at the last census the married female population of England and Wales, between the ages of fifteen and fifty-five, amounted to 2,563,894, the loss of fcetal life must be enormous. The date at which the majority of abortions occur, is from the second to the fourth month of pregnancy. Taking the particular pregnancies in which abortion is most likely to happen, there seems to be CAUSES OF ABORTION. 179 greater danger of the accident in the first pregnancy, particularly among the upper classes, and in those later pregnancies which occur before the cessation of the menses. We have seen, while considering the signs and disorders of pregnancy, that the uterus is in reflex relation with many impor- tant organs. These organs react upon the uterus, and prov,e in many cases the predisposing or active causes of abortion. In my work on " Parturition," I stated that I had seen abortion caused by irritation of the Mammary nerves, as when abortions occur during lactation from the irritation of constant suckling. That it is not mere weakness or exhaustion in some of these cases is proved by the fact that the mammary secretion may cease upon the occurrence of impregnation, but that a plentiful supply of milk returns after the occurrence of abortion. The contraction of the uterus after delivery from the irritation of the mammas is well known. When I first suggested this cause of abortion in some cases, the idea was roughly criticised, but it has been adopted in the recent work of Dr. Gunning S. Bedford, of New York, and Professor Scanzoni has founded upon it a method of inducing premature labor by irritation of the mammae. Irritation of the Gastric nerves will sometimes produce abor- tion. It is astonishing-what an amount of nausea and vomiting the uterus will bear without being excited to expel its contents, and there is a belief, generally well founded, that sickness, pre- vents the occurrence of abortion from rigidity of fibre or imper- fect uterine devolution. But cases do occur in which abortion is apparently brought on, as a reflex pathological phenomenon, produced through the medium of gastric irritation. Irritation of the Trifacial nerves may also produce abortion. This happens sometimes from the irritation of cutting the wisdom teeth, the extraction of a decayed tooth, or the irritation of constant odon- talgia. Vesical or Renal irritation, as from the presence of a stone in the bladder, or irritation of the kidneys in albuminuria, is sometimes the cause of abortion. Ovarian irritation has a like effect, as shown by the tendency to abortion at the catamenial dates, particularly in women who have been the subjects of dysmenorrhoea. The production of abortion by the irritation of the Rectal nerves is a well recognized occurrence. It may hap- pen from haemorrhoidal inflammation, the irritation of ascarides, the action of violent purgatives, diarrhoea, or dysentery, or the 180 COLPEURYSIS IN ABORTION. opposite condition of excessive constipation. The mechanical efforts of vomiting, coughing, sneezing, or straining of any kind, will occasionally cause abortion in delicate subjects. Irritation of the Uterus and Vagina may excite abor- tion. Plugging the vagina is sometimes practised as a means of inducing abortion artificially. [This is effected by colpeurysis. The instrument used to effect this purpose is a simple bag of vulcanized india-rubber, which is to be introduced into the vagina and then dilated with air, warm or cold water, as may be deemed expedient. After being more or less fully expanded (and it may be advisable at first to but gradually inflate it, and increase as the pressure is less and less inconvenient) the aperture is closed by a stop cock, and the bag allowed to remain in the vagina. In Figs. 49 and 50, this instrument may be seen, it is there applied in the same manner, but for the purpose of overcoming a retroversion of the uterus, and is there introduced into the rectum. The meaning of the Greek words from which the name of this instrument is derived, is vagina-dilator, and expresses the idea of the effect it produces, dilating the vagina and even pulling open the os uteri, and by its forcible presence, exciting by sympathy, action of the uterus. The colpeurynter makes a superior tampon, and as the bag may be filled with cold water and frequently changed by merely opening the stop-cock, emptying it and refilling, the advantage of this instrument may be perceived in cases of placenta-praevia and uterine haemorrhage when tamponing is sometimes judged expedient.] In abortion excited by violent horse or carriage exercise, the accident depends upon the irritation of the uterus, and espe- cially the os and cervix uteri, by the head of the child, during the succussion which occurs. Coitus, plugging the os uteri, dis- ease of the os and cervix, procidentia, anteversion, and retrover- sion, the implantation of the placenta over the os uteri, cancer, fibrous tumors of the uterus, mechanical injuries and metritis, may all cause abortion. In abortion depending upon the disease or death of the. ovum, it is the irritation of the uterus by its abnormal contents, which directly excites the act of abortion. In the case of abortion from the irritation of the uterus by the state of the rectum, stomach, mammae, etc., the action of the OXYTOXICS FOR ABORTION. 181 uterus is, in the first instance, purely excito-motor and reflex. When, however, the reflex action of the uterus is established, the peristaltic action of the organ combines with the reflex uterine action. In the case of abortion from local uterine irritation, or from the irritation of the uterus by a dead or diseased ovum, the reflex and peristaltic actions of the uterus are induced simul- taneously. We may consider abortion from reflex action, as being in some points of view comparable with spasmodic asthma, or any other excito-motor disease. From certain irritating causes, an excitable condition of the excito-motor arcs concerned in partu- rition is induced. This state of excitability once produced, slight causes, which in healthy subjects would produce no dis- turbance whatever, are sufficient to produce morbid or spasmodic parturition. This excitability is not suddenly reached. It re- quires that the nervous arcs, whether mammary, rectal, of other, should be irritated for a considerable time, when an excitable, charged, or polar state of the uterine nervous system is produced. The period preceding a case of reflex abortion may be likened to the time preceding an epilectic attack. Certain agents have the power of exciting the uterus to con- tract, and are hence called Oxytoxics. The oxytoxic effects of the ergot of rye, cannabis Indica, savin, borax, galvanism, and the inhalation of carbonic acid, or its retention in the blood in asphyxia, are very generally believed in. Abortion has been often caused by the ergot of rye. [?] During accidental or inten- tional poisoning by carbonic acid, the ovum has been found to be expelled. In the celebrated razzia in Algeria, conducted by the present Marshal Pelissier, in which a number of Arab women were suffocated in the caverns of Dahra, many of those pregnant were found to have aborted. The same thing occurred in a similar exploit by the celebrated Chevalier Bayard. In other forms of death from asphyxia, as in drowning, sudden abortion has been known to occur. Many of the poisons, when taken by pregnant women in fatal doses, have caused, in the first instance, the loss of the ovum. Certain pathological states excite contrac- tion of the uterus, and are frequently the cause of abortion. Loss of blood; exhaustion, from whatever cause arising; the syphilitic poison ; mercurialization ; zymotic diseases, as small- pox, scarlatina, and fever ; chorea; visceral inflammation ; albu- 182 SEVERE INJURIES WITHOUT ABORTION. minuria; and according to Lugol, the strumous diathesis, may excite the uterus to the premature expulsion of its contents. Emotion is another important cause of abortion. It may be pro- duced by the emotions of fear, anger, grief, or any other violent mental disturbance. Under the influence of terror and pain, martyred women have aborted at the stake. Of these oxytoxic agencies, some affect the nervous centres, and are in this respect to be distinguished from the ex-centric or reflex causes of abor- tion. The ergot of rye, for instance, passes into the blood, and affects the spinal centre, being specially directed to the lower portion of the spinal marrow, and to that part of it in relation with the uterus. In the case of emotion, the influence is distinct from other causes of abortion, in being dynamic or psychical. Others, amongst the causes of abortion now enumerated, prob- ably affect the nutrition and life of the ovum, and in this way lead to abortion. The amount of disturbance to which some women may be exposed without inducing abortion is extraordinary. Mauriceau relates the case of a woman, in the seventh month of pregnancy, who fell from the window of a house, and, besides extensive bruises, broke one of the bones of the fore-arm and dislocated the wrist, without aborting. Dr. Henry Davies once told me of the case of a woman, who, throwing some water from a window, lost her balance, and fell into the street, breaking both her thighs, but recovered without abortion. Dr. Marshall Hall ren- dered a frog tetanic by strychnia at the time the oviduct was full of ova, and the ova were not expelled during the tetanoid symptoms, but some days afterwards, when the spasms had nearly disappeared. Dupuytren relates the case of a woman who had become the subject of traumatic tetanus during preg- nancy, but who, nevertheless, recovered and went her full time. Other women abort upon the slightest occasion. A habit of abortion appears to be acquired in some cases, and abortions are repeated many times in succession, without our being able to detect any very obvious cause. I have known a woman abort ten times in fi>e years; and another who in eight years had fourteen abortions, and gave birth to one still-born child.. Madame Boivin mentions that she had ascertained by dissection that, in women who abort regularly, the uterus has sometimes contracted adhesions to other organs. I have several times WHY FISSURES OF THE CERVIX PRODUCE ABORTION. 183 known abortions to occur in women who had been the subjects of sloughing and cicatrization of the vagina, after previous labors, or who had been affected with pelvic cellulitis and pel- vic abscess. In some women it appears as if the uterus could not be developed beyond a certain point. But these points do not acconnt for all the cases of habitual abortion. [The reason why the uterus appears incapable of being de- veloped beyond a certain point seems to me to be owing to fis- sure of the os and cervix uteri. If we accept the view of Stolz relative to the symptom of the neck, vide page 138, and recog- nize that the cnange in the os uteri commences at the external os, and not at the internal os, the explanation is easy. [Mr. Whitehead, in his able work on Abortion and Sterility, recognizes this cause of abortion, but without giving its ra- tionale. He states " that it is found to exist in twenty to twenty- four out of every hundred cases of abortion not resulting from accidental causes. It is always accompanied by a degree of inflammatory induration, which extends more or less deeply on each side of the fissure; this is readily detected by the touch, the circumference of the orifice being uneven and lobulated. Sometimes only one fissure exists; this generally occupies one of the commissures, or it may divide one of the labia into two portions, and in this case the hardness may not extend beyond the boundaries of the ulcerated chink." These fissures may sometimes amount to actual rents, entirely dividing the os uteri, several cases of which I have spoken of in my work on the Causes and Curative Treatment of Sterility. I borrow from it a representation of an instrument made for the purpose of exposing the interior cavity of the os uteri, by means of which the fissure may be observed throughout its whole extent. Dr. Henry Bennett, in a recent article, recognizes this cause of frequent abortions. This point is farther enlarged upon on a subsequent page (205).] 184 ABORTION A DECIDED EXFOLIATION. There is one other cause of abortion on the maternal side, which I believe to be of very great importance. In treating of menstruation, and the formation of the decidua, we have seen that the mucous membrane of the uterus is concerned in the menstrual discharge, and that the decidua consists of the altered mucous membrane itself. Now, if this doctrine of the formation of the decidua be correct,—and there is hardly any matter with- in the limits of modern research, upon the subject of generation, which seems better established; if this be true, I say, we must push the matter into the domain of pathology. Dr. Simpson has done this in a very able manner in relation to membranous dysmenorrhoea. Denman and others saw that the mass dis- charged in these cases resembled the decidua, and made the comparison between the two substances. But Dr. Simpson, after the true nature of the decidua had been made out, was able to carry the comparison further, and he has proved that the mem- brane discharged in membranous dysmenorrhoea is, like the de- cidua, the mucous membrane of the uterus itself hypertrophied, and exfoliated or thrown off at a catamenial period. Many years ago I drew a comparison between menstruation and abor- tion and parturition. As regards the decidua, there is no great difference between an abortion a few weeks after conception and membranous dysmenorrhoea, except that in abortion the decidua is loaded with the fruit of the womb, and may be discharged more or less in a state of disintegration. Every abortion really consists in the throwing off of the mucous membrane of the uterus and the ovum which has been developed upon its surface. I believe that in many cases of abortion, as in menstruation of healthy and morbid type, the disintegration and exfoliation of the mucous membrane or decidua is the first step in the process, and the direct cause of the loss of the ovum. From this point of view we must consider the show in cases of abortion, and the continuous sanguineous discharge, as similar to the discharge in menstruation. In many cases it happens that abortion is threat- ened, and there is a colored discharge for many days without the loss or injury of the ovum. In these cases the discharge probably takes place from the surface of the decidual mucous membrane, as suggested by Dr. Matthews Duncan, in reference to menstruation during pregnancy. Abortion does not take place in such cases, probably because the disintegration of the DISEASE OF THE FG3TUS A CAUSE OF ABORTION. 185 decidua does not occur at the part at which the ovum or the pla- centa is implanted upon it, or not to a sufficient extent to injure it. In abortion in the latter periods of pregnancy, the compari- son between the loss of the ovum and menstruation holds good ; only at this time the decidua serotina has become by far the most important part of the uterine mucous surface. In all cases of abortion, this menstrual condition of the developed mucous membrane of pregnancy plays an important part, and is the chief cause of the sanguineous discharge; but in many cases it is probably the actual cause of abortion. The tendency of abor- tion to occur at the catamenial dates has long been a matter of observation. In abortions occurring at the menstrual dates of pregnancy, the periodical influence of the ovaria, as well as of the uterine mucous membrane, must be considered. We have now considered the principal causes of abortion re- ferable to the mother: others remain, in which disordered con- ditions of the chorion and decidua, or of the maternal and foetal portions of the placenta, are concerned. There is also another class of causes, in which the foetus and its diseased conditions tend to the production of abortion. A new cause of abortion, of great importance, affecting the maternal and fcetal structures of the ovum, has been made out within the last few years, chiefly by the original researches of Dr. Robert (Barnes: I allude to Fatty Degeneration of the chorion and placenta. Kilian had noticed a solitary case, but the first systematic account of the disease we owe to Dr. Barnes, who was assisted in his microscopical investigation of the subject by Dr. Hassall. This form of degeneration may affect the secundines at any time between the early weeks of pregnancy and the termination of gestation. Fatty degenera- tion may exist in the placenta as a post-mortem change—that is, it may occur in utero after the death of the foetus. It may happen also as the result of the transformation of effused fibrin in inflammatory disease of the placenta, or of a clot of blood in haemorrhagic effusion. Lastly, it may consist of the metamor- phosis of portions of the maternal and foetal structures of the placenta during the life of the foetus. The latter pathological phenomenon is that which is of the chief importance in relation to abortion. In a placenta affected with fatty degeneration, the lobes of 186 DISEASE OF PLACENTA A CAUSE OF ABORTION. the placenta are altered in appearance, some of them being of a yellow, fatty color, brittle, and exsanguine; the rest presenting their ordinary characters. Examined more minutely, the tufts are found to be glistening, hard, and tallowy, and not expand- ing when placed under water, as is the case with the villi of healthy placentae. Under the microscope, the villi are seen to be studded with spherules and droplets of fatty matter and oil. The fatty material is found principally in the cells of the villi, and in the coats of the blood-vessels of the villi. When the fatty degeneration of the vessels exists to any extent, the vessels do not carry red globules. The villi and the vascular loops affected with degeneration are knobbed and misshapen in appearance. Dr. Barnes believes the degeneration, or retrogres- sive metamorphosis, to commence mostly in the villi and decidual cells of the placenta. He has pointed out that this state of things must materially interfere with the nutritive and circulatory functions of the placenta, and that if it proceed to Fig. 53. Cells of the decidua as they appear in the healthy placenta. 420 diameters. any great extent, it must inevitably destroy the foetus by cutting off the connection between the maternal and fcetal circulations. PLACENTAL APOPLEXY A CAUSE OF ABORTION. 187 Dr. Barnes supposes that, from the friable, non-resilient condi- tion of the degenerated lobes of the placenta, partial separations must occar, leading to haemorrhage and abortion. He suggests also that partially degenerated blood-vessels may burst, and sometimes lead to intra-placental haemorrhage, or placental apoplexy. Sometimes the dead ovum is at once expelled; at Fig. 54. Cells of the decidua in a state of fatty degeneration. 420 diameters. other times the chorion or placenta remains in connection with the uterus, and undergoes a further metamorphosis, so as to con- sist very largely of fatty matter, before it is expelled. In all probability, many of those cases in which pregnancy repeatedly goes on in the same woman to the full time, and the foetus is found to have died shortly before the time of birth, the cause of death will be found to be fatty degeneration. The metamorphosis of portions of the placenta explains many of the descriptions of the placenta in a morbid state found in obstetric authors before the subject of degeneration was under- stood. Dr. Druitt has contended, that in the normal placenta, at the full time, the signs of commencing fatty degeneration are present, and this is no doubt true; but, under healthy conditions the fatty metamorphosis cannot be extensive, otherwise the 188 SYPHILIS A CAUSE OF ABORTION. health of the foetus could not be preserved. Dr. Druitt points out, that in the placenta, as a caducous organ, the signs of deca- Fia. 55. 1, Vessel with its investing chorion: 2, The same deprived of its chorion; 3, Chorion detached, showing its cellular function. 420 diameters. dence begin to be present at the time of its maturity. As regards the cause or origin of the fatty degeneration of the pla- centa, chorion, or decidua, Dr. Barnes refers it chiefly to an imperfect germinal or fermative force on the side of the ovum. He is also of opinion that, dependent as the ovum is upon the vascular system of the mother for support, any imperfection in the nutriment supplied to it must contribute to the diseased state of the placenta. It is only upon this hypothesis that we can hope to control this malady, by rendering the system of the mother as healthy as possible during gestation. The later researches of Dr Barnes lead him to believe that constitutional syphilis, maternal or paternal in origin, is a frequent cause of fatty placenta. PLACENTITIS A CAUSE OF ABORTION. 189 The placenta is subject to congestion and inflammation and their results, and these affections are not nnfrequently the causes Fie. 56. 1 and 2, Branches partially deprived of chorion, and showing much fatty matter; 8, Blood-ves- sel entirely deprived of its chorion, and in a state of degeneration. 420 diameters. of abortion. Congestion of the placenta leads to what is termed apoplectic effusion. Blood may be poured out either on the fcetal or external surface of the placenta; it may escape into the parenchyma of the organ ; or it may be poured out on the maternal surface. The loss of blood may lead to the death of the foetus, and in this way produce abortion, or it may excite the separation of the ovum, and contraction of the uterus. In other cases., the blood effused coagulates, its fluid portions are removed, and a fibrinous mass remains without doing any great injury. In inflammation of the placenta, or placentitis, effusion of lymph may occur, or the disease may pass on to hepa- tization, suppuration, or gangrene. Sometimes, when the in- flammation affects the internal surface of the placenta, adhesions form between the placenta and the external surface of the ovum. 190 PLACENTAL CONGESTION A CAUSE OF ABORTION. In this way, the placenta has been found adherent to the fore- head or body of the foetus. This disease has been investigated by Brachet and Wilde, and one of the earliest and most elaborate memoirs of Professor Simpson was chiefly devoted to this subject. Its symptoms are obscure, consisting of pain in the uterus, near the site of the placenta, pains in the back and thighs, and general fever. In cases where I have suspected pla- centitis, I have examined with the stethoscope, but have not found any modification of the uterine sounds. The causes of placentitis are not very obvious, beyond mechanical injuries, and the great afflux of blood to the organ, which occurs during pregnancy. Congestion and its results are probably common causes of abortion, though it is by no means certain that in all cases of abortion, in which effused blood is found in the pla- centa, or the membranes, the effusion has been the cause of abortion. In many cases, the effusion occurs, without doubt, Fig. 57. An apoplectic ovum; blood being effused in masses under the foetal surface of the membranes. during the progress of abortion from other causes. The treat- ment of placentitis and placental congestion consists in local or general blood-letting, according to the amount of pain and the SYPHILITIC OVUM A CAUSE OF ABORTION. 191 constitution of the patient, counter-irritation over the uterus, and other means for equalizing the circulation. Dr. Simpson is of opinion, that many of the cases of repeated abortion in the same person depend upon placental congestion. The placenta is liable to other diseases, which have a tendency to repetition, such as calcareous degeneration, tubercular deposits, and atro- phy or hypertrophy. In the case of a syphilitic ovum leading to abortion, the placenta is very commonly diseased. When from any cause the foetus dies, the circulation in the foetal portion of the placenta is suspended ; this in turn affects the circulation on the maternal side; the ovum becomes a foreign body, and abortion generally takes place. Sometimes, however, the placenta is still nourished imperfectly, and the dead ovum is retained in utero for a variable time. The foetus is liable to many diseases which may tend to the death of the ovum, such as inflammation of its serous membranes, dropsies of the serous cavities, or the amnion, disease of the liver or kidneys, tubercular diseases, diseases of the umbilical cord, knots upon the cord, twisting of the cord tightly round the neck of the child, and various other affections which are sufficient to destroy its vitality. I have seen a case, in which the head was nearly amputated by the twisting of the cord round the neck. Proba- bly a diseased ovum excites the uterus to expulsive contractions in many cases, before actual death of the ovum has occurred. Fig. 53. Ovum showing morbid enlargement of the umbilical cord LECTURE XII. TREATMENT OF ABORTION. Gentlemen :—The first Symptoms of Abortion are a san- guineous discharge, and the occurrence of lumbar, hypogastric and coxal pain. The pains which precede abortion are very much like those which precede or accompany a catamenial period. Some women abort, however, without having suffered much, if any pain. It frequently happens that a distinct rigor, or frequent shiverings, usher in abortion. There is sometimes diarrhoea, and still oftener, an irritable condition of the bladder. Coldness of the breast and abdomen is sometimes complained of, and there is often a cessation of sickness, where this has been troublesome. On being called to a case of supposed abortion, an examination should always be proposed, and made, if possi- ble. It may happen that in cases of supposed abortion there may be no pregnancy at all. Great care should be taken, on introducing the finger, not to give pain or use any violence, lest the tendency to expulsion should be increased. In threatened abortion, the os and cervix uteri will generally be found open to some extent, and the body of the uterus may be felt in front of the os, lower in the pelvis than natural, and hard, as if firmly contracted. When abortion is actively proceeding, the ovum, or part of the ovum, may sometimes be felt high up in the cervical canal, or it may be partly extruded from the os uteri. The first consideration, in a case in which the symptoms of threatened abortion have occurred, is whether or not the ovum can be preserved. With this end in view, all irritations of a reflex kind should be avoided or removed, as much as possible. Gen- eral, local, or vascular excitement should be treated by a sooth- ing regimen and diet. It is rare that cases are met with requir- ing general blood-letting; but leeching is sometimes useful in cases of uterine plethora, particularly when the symptoms occur 192 PREVENTION OF ABORTION. 193 at what would, in the absence of pregnancy, have been a cata- menial date. The leeches should be applied to the inside of the thighs, or the perinaeum. When nervous excitement predomin- ates, a full opiate is of great service. Opiates, in full doses, are also especially called for when there is intermittent uterine pain, or the continued pain of the back and lower part of the body similar to painful menstruation. Dr. Fleetwood Churchill has given the cannabis Indica with good effect as an anodyne, and with a view to its restraining sanguineous discharge. In the earliest abortions, astringents are very valuable, the loss of blood in such cases very much resembling monorrhagia. The acetate of lead, in combination with opium, the mineral acids, the oxide of silver, alum, gallic acid, are the best remedies of this kind. If the discharge is profuse, iced drinks should be given. Otherwise, the beverages of the patient should be cool, without being absolutely cold, in order to avoid uterine contrac- tion. In the treatment of abortion, it must always be borne in mind, that in diet and medicine any agents which excite con- traction of the uterus may arrest haemorrhage for the moment, but with danger of exciting further separation of the ovum. We must be careful, therefore, not to excite any powerful uterine action. The local application of cold to the vulva, and the introduction of sponge, or pieces of lint dipped in water, into the vagina, are very useful, within certain limits ; but it must be remembered that excessive cold excites uterine contractions, and so, also, does the sponge or linen plug, if it should be large enough to irritate the vagina mechanically. Perhaps the most important of all the means at our disposal for the relief of abortion is rest in the horizontal position. The patient should be kept in bed in a cool apartment, lightly covered with clothes, as long as any colored discharge continues, and for some days afterwards she should be kept upon a couch, and not allowed to assume the upright position or to Walk. When the uterus is in the irritable and congested condition which accompanies abor- tion, the standing posture, or considerable movement of any kind, greatly adds to the probabilities of abortion. The mind of the patient should be kept as quiet as possible, and all excit- ing or alarming intelligence withheld from her. The bowels should be kept open, if necessary, with the mildest laxatives. I prefer the senna confection, with a little bitartrate of potash, 13 194 PERIODIC CHARACTER OF ABORTION. as an aperient. Castor oil, as I believe, irritates the uterus and mammae, and should not be given. When the threatening of abortion has occurred at a catamenial date, every precaution should be taken, as the next monthly period comes round, in the way of avoiding irritation, and preserving quiet of body and mind. Every pregnant woman should be told to take note of the catamenial dates throughout pregnancy, and observe greater care than usual at these times, particularly if she has been the subject of abortion. The attempts to prevent abortion should be carried out perseveringly, as it sometimes happens that women suffer from the symptoms of abortion for a considerable time, slight sanguineous discharges lasting for weeks, and yet, with continual care, they go on to the full term. It sometimes happens that the bleeding is very profuse, and the os uteri so closed that the finger could not possibly be introduced into the uterus. All the more powerful astringents may have been tried in vain. In such cases the vagina must be plugged firmly with lint or sponge. This arrests the bleeding almost invariably, and tends to the promote coagulation at the mouths of bleeding ves- sels. If, however, it is necessary to continue the plugging for any length of time, the uterus becomes excited by the mechani- cal irritation, and throws off its contents. Sometimes the loss of blood is so great as to require the free administration of brand}', ammonia, and other stimulants. As abortions fre- quently spread over a considerable time, every care should be taken to support the strength of the patient. In abortions at the fourth or fifth month, the haemorrhage may be so profuse and sudden as to be alarming from the first. This is particu- larly the case in abortions occurring about the time of the cessation of the catamenia. In such cases, if the haemorrhage cannot at once be arrested by astringents, cold and the tampon, the membranes should be ruptured with a view to stop the haemorrhage, and to excite expulsive action of the uterus. When an abortion is threatened, the accoucheur should order all the discharges to be saved for his examination. Every clot and every portion of solid matter should be carefully inspected. Otherwise it may happen that the patient or her nurse shall tell you she has aborted when she has not done so, coagula havin^ been mistaken for the ovum. Or it may occur that the ovum having passed unnoticed, and slight or profuse haemorrhage con- TREATMENT OF ABORTION. 195 tinuing, as it sometimes does, for a considerable time, the accou- cheur is puzzled by expecting an abortion long after it has been accomplished. In connection with these points, it must be borne in mind that cases occur in which the ovum appears to be dissolved, and slowly discharged with sanguineous matters, just as the decidua is discharged in the lochia after parturition. A delicate ovum of a few weeks may disappear within the uterus, as occurs in certain cases of molar gestation, and the mem- branes may be broken down and discharged as detritus. Either of these three cases may prove very embarrassing to the practi- tioner. Whatever care may be observed, cases will occasionally occur in which women who have passed two or three menstrual periods, and exhibited the signs of early pregnancy, will be seized with the symptoms of abortion, and suffer from a sanguin- eous discharge for a considerable time, without passing any detectible portions of an ovum. After this the patients may men- struate regularly, and it becomes exceedingly difficult, or impos- sible, to decide whether they have aborted or suffered from a temporary suppression only. ^ The indications which should make us abandon all hope or intention of saving the ovum are, sudtlen losses of blood to such an extent as to imperil the life of the mother, or such a continu- ous drain as seriously to endanger her health ; it being also cer- tain, or nearly so, that in such cases the ovum is diseased or already dead. If, on examination, we can feel the ovum at the os uteri, or in the cervix uteri within reach of the finger, we may be certain that its expulsion is only a question of time. As a rule, there is little hope of saving the ovum after the rupture of the membranes and the discharge of the liquor amnii. I have, however, seen at least one case in which gestation went on to the full term after the discharge of the liquor amnii at the fifth month. Foetid discharges, particularly in early abortions, are a pretty sure sign of the death of the ovum. When all expectation of saving the ovum has been aban- doned, means must be taken to obtain its removal from the uterus. If the bag of the early ovum can be felt with the fin- ger in the cervix uteri, it can generally, by careful manipulation, be separated from the uterus, and got away by the finger alone. Sometimes it is necessary to introduce the hand into the vagina, in order to get the finger into the uterus ; and if the haemor- 196 INSTRUMENTAL ASSISTANCE IN ABORTION. rhage is alarming, the case urgent, and the os uteri sufficiently dilated to admit the finger, there need be no hesitation in adopt- in o- this measure. I have never seen any ill effects arise from such an introduction of the hand and finger. When the os uteri is undilated, and the haemorrhage is great, Dr. Simpson recommends the introduction of one of his sponge pessaries, with a view to the mechanical dilatation of the os and cervix. The only precaution necessary in such cases, as in all instances in which sponge is used in the vagina, is not to allow the sponge to remain long enough to become foetid. The ergot of rye and the cannabis Indica may be given for their oxytoxic effects in cases where it is thought unadvisable to remove the ovum, or portions of the ovum, mechanically. Galvanism has been sug- gested by Dr. Robert Barnes, and from what I have seen of its action in cases of intra-uterine polypi, I have no doubt it would contribute to expel an ovum in a difficult case of abortion. We may turn the reflex connection between the rectum and the uterus to great account in the treatment of abortion when there is no hope of saving the ovum. A drastic cathartic enema will often complete the expulsion of an ovum in the most rapid man- ner. Yarious instruments have been proposed and recom- mended for the mechanical extraction of a partially-detached ovum. There is, however, no instrument equal to one or two fingers when they can be introduced. The last invention of this kind is an instrument proposed by Dr. Fleetwood Churchill, on the principle of the familar apparatus for getting a cork from the inside of a bottle. In France, a small forceps, somewhat resembling the lithotomy forceps, is used for the same purpose. Dewees invented a wire crochet for the extraction of the ovum. [A far better instrument is the polypus forceps with rache* handle, invented by Mr. Luer of Paris. By its broad edges a large portion of the ovum or placenta is seized, which is firmly REMOVAL OF EMBRYO. 197 held by the grooved edge, and is not easily tearing away, as is the case with other instruments apparently more conve- nient.] It must be said, however, that, with all instrumental devices for the removal of the embryo, there is danger of injuring the uterus, and with the hand in the vagina, a case can hardly occur in which the embryo, membranes, or portions of the latter, when retained, cannot be detached and brought away by the finger. Time and patience are sometimes necessary for this manipula- tion, but I have never known it to fail. [Any one who has had much experience has discovered the difficulties which not unfrequently occur in the attempt to remove the whole or the remaining detached head of an embryo. When the finger is introduced into the cavity of the uterus, the further attempt to pass it around the embryo, will, not unfre- quently, push away the uterus, so that almost insensibly the fin- ger is out of the organ, the hand upon the abdomen not suffic- ing to hold the uterus down into the cavity of the pelvis. Then the diameter of the head is greater than the diameter of the undilated and rigid os. To obviate these difficulties I have invented the instrument represented on p. 198. The end A is moved by a screw B in the handle. Being introduced straight, by the side of the finger into the cavity of the uterus, the screw is turned by an assistant or by the unemployed hand of the operator. This bends the end A, till it is almost perpendicular to the staff, and is then to be directed externally and catching upon the internal os the uterus may be held firmly down while the finger can be moved freely in the cavity. When the ovum, embryo, detached head, or pla- centa, is surrounded by the finger, the end A, can be so turned as to oppose the finger, catching what may be between them, retaining the neck of the embryo (or polypus) in the notch a / crushing the head ; or assisting in the traction necessary for deli- very. Advantage has been taken of the mobility of this instrument to attach to it several other instruments which may be seen in the cut, so that by unscrewing the spatula a, Simpson's sound X, probe pointed bistoury W, scarificator, portecaustique Y, and instruments may be easily substituted as desired.] I have seen cases where it was necessary to give chloroform 198 CHLOROFORM IN ABORTION. before introducing the hand. In a case I saw with Mr. Ballard, „ limiilitniiniTm of a retained placenta in an abortion at the fifth or sixth no other means would have enabled us to extract the rer CONDITION OF THE OVUM IN ABORTION. 199 the ovum. The ofdinary modes of procuring its removal had been tried in vain. The patient was in such a state of frenzied excitement that any introduction of the hand would have been impossible while she remained conscious. The cord had bro- ken and the placenta had been retained thirty-six hours, and there was no choice but that of leaving the placenta or giving chloroform. There was no difficulty in introducing the hand, but the placenta had to be peeled from the surface of the uterus. The dangers of retained placenta are well known, and in a case of difficulty I should not hesitate to advise the use of chloro- form in similar cases. The condition in which the ovum is expelled varies greatly in different cases. The most favorable way in which an early abortion can occur is, where the detachment of the entire ovum takes place before the act of expulsion occurs. The perfect ovum is then expelled at once, and the uterus contracts without much haemorrhage. In other cases the membranes are ruptured, and the small foetus comes out alone or enveloped in the amnion, or the membranes may be discharged piecemeal, leaving the ovum to escape afterwards. As a general rule,-the membranes remain after the expulsion of the foetus ; and the earlier the abortion, the longer the membranes or placenta have a tendency to remain. This is probably owing to the extended adhesion of the ovum to the internal superfices of the uterus, and the feeble power of the uterus to contract on its contents. Sometimes the membranes of an early ovum will remain for weeks, but in such circumstances there is not the same tendency to decomposition and its dangers, as there is in the case of placenta at the full term. The mechanism of abortion varies considerably, according to the time between conception and the term of naturallabor at which the accident happens. No doubt the abortion may occur in cases where conception has taken place just before a period, when the motor act of expulsion would probably be limited to the Fallopian tubes, the ovum being carried out of the uterus with the menstrual discharge. In cases occurring in the early months, the canal of the cervix and the os uteri have to be dilated before the ovum can pass, and this process of dilatation occupies a considerable time, and frequently causes much suf- fering. When the dilatation has occurred, the ovum is expelled 200 DANGERS OF ABORTION. by the contractions of the imperfectly-developed uterus. The contractions of the uterus occur periodically, and are accom- panied by periodical pains, as in labor at the full term. The nearer the time at which the abortion takes place is to the time of labor, the more closely do the pains and the motor action and mechanism resemble those of natural parturition. In abortions occurring after the formation of the placenta, the tendency, as regards the expulsion of the ovum, is to imitate labor at the full term. The cervix uteri is slowly dilated, the membranes rup- tured, and the foetus expelled, to be followed, at a longer or shorter interval, by the membranes and placenta. In the early months, the difficulty occurs, not in the passage of the foetus through the pelvis, but in the dilatation of the undeveloped cer- vical canal. As gestation advances, and the cervix uteri becomes developed, the difficulty of passing through the cervix becomes diminished, while that of passing the pelvis is increased. When the ovum is small, the contractions of the uterus are chiefly or solely concerned in its expulsion ; but when it is large enough to distend the vagina, the abdominal and respiratory efforts are called into play. Usually, an abortion is not attended by any great danger. Women recover rapidly from the loss of an ovum, and there is a remarkable aptitude for conception afterwards. They do, however, sometimes perish from loss of blood, convulsions, or rupture of the uterus. They are also liable to the dangerous and fatal affections which attend the puerperal state. Tetanus, resembling the traumatic disease in character, has been known to occur after miscarriage, and in rare cases blood has passed through the Fallopian tubes into the peritoneum, causing death by peritonitis. Abortion occurring from small pox and scarla- tina is especially dangerous to the mother. When women abort frequently, great damage is done to the general health ; a pro- found anaemia is caused; and patients may die of secondary dis- eases arising out of the debility induced by the recurrent mis- carriages. When the whole of the ovum has been expelled, it is rare to meet with any profuse post-partum haemorrhage. The uterus is at once so diminished in size as to prevent the risk of bleeding. It happens, however, that occasionally small portions of the membranes are left in utero and are a source of irritation and bleeding for weeks after the loss of the ovum. When the entire TREATMENT AFTER ABORTION. 201 ovum is extruded, or brought away completely in detached por- tions, the woman is at once in a state of ease. A discharge, generally similar to the lochia, continues for some days. As regards rest and other management, a patient, after a severe abortion, should be cared for in the same way as a woman who has been delivered at the full term—that is, she should be kept in bed and ordered a light, unstimulating diet, until she has regained her strength. The breasts are' sometimes stiff and painful, but rarely give much trouble after an abortion. We must take cognizance of diseased states of the placenta in the treatment and prevention of abortion. When the foetus is threatened with death because the placenta cannot perform its nutritive and respiratory functions, we may, through the mother, act upon the placenta, and assist it in the performance of its factions. Dr. Power prescribed the inhalation of air containing an increased quantity of oxygen, or the use of medicines contain- ing a large proportion of ox}'gen in a loose state of combination, as nitric acid, in cases where the child has been lost repeatedly in the latter months of pregnancy. Dr. Simpson states that he has found chlorate of potash useful in cases where the fcetal res- piration is imperfect. Every care should be taken in such cases to keep the blood of the mother in a healthy state. It is evi- dent that the sanitary condition of the foetus must mainly depend on the condition of the arterial blood of the mother, this being the medium in which the embryo respires. It has been recommended that, in cases of repeated peritonitis or cere- bral disease in the foetuses of the same mother, mercurialization and other means should be employed with the view of reaching the ovum through the maternal circulation ; but, in the present state of our knowledge, our means of diagnosis in diseases of the foetus are too obscure to render therapeutics of much value. In syphilis affecting the mother, or when the father is syphilitic, there can be no question of the propriety of mild mer- curialization as a means of warding off the dangers of abortion, regard being had to the feet, that the careless use of mercury may itself be the cause of abortion. In the prevention of abortion from fatty generation of the placenta, the strength of the mother should be supported in every way. The chlorate of potash, nitric acid, mild preparations of iron, and, above all, fresh air, should be recommended. The treatment of fatty placenta should be the same as fatty heart, or fatty degeneration of any other organ. 202 PREVENTION OF ABORTION. The prevention of abortion is an important subject. The whole of the treatment of the disorders of pregnancy has a direct. bearing upon this subject. In women who abort from habit, when the nervous system is chiefly concerned in the production of the accident, all emotional disturbance and reflex sources of irritation should be avoided as far as possible. The pregnant woman should not suckle, or be subjected to any mammary irritation. Mr. Lloyd has related a case in which a small tumor having been removed from the breast of a pregnant woman, she aborted, and died of metritis. Irritation of the dental nerves should be guarded against. The rectum should be remembered, not merely as a neighbor to the uterus, but as possessing an excitor surface in reflex relation with the uterus. Ovario-uterineand vaginal irritation should be soothed, and excitement avoided, particularly at the catamenial dates. It is a useful point in the Periodoscope I constructed some years ago, and some thousands of which have been used by the pro- fession, that it points out, at a glance, the catamenial dates of any pregnancy. The late Dr. Griffin, of Limerick, recommend- ed large doses of quinine in the case of women who abort repeatedly at the same date of pregnancy. [I would especially caution practitioners in this country from prescribing quinine to pregnant women generally, and particularly where there is much uterine susceptibility. In my experience quinine will more surely produce abortion than ergot, which does not seem to have the power to excite uterine action in a womb in a healthy state, but acts as a stimulus when there is a diseased condition, or with unusual susceptibility, as where labor pains have com- menced.] Mr. White, of Manchester, recommended cold or tepid bathing, with success, as a preventive of abortion. Some accoucheurs advise a daily enema of cold water, in women of weak, irritable habit. When the tendency to abort is very strong, nothing is so likely to prolong gestation to the full term as absolute rest in the horizontal position. When all other means fail, an attempt should be made tp eradicate the abortive diathesis by a year's marital separation, and a tonic treatment in the meantime. [Except in rare instances, the haemorrhage before full time is always preceding the delivery, while that at full time is poste- rior to it. Haemorrhage not unfrequently occurs at the next menstrual period following conception. The woman, especially PERCEPTIBLE CAUSE OF ABORTION. 203 she who has never borne children, after half suspecting from various signs that she was pregnant, at her usual period is not only u regular," but profusely so, with more than usual pain, and with numerous clots which have not previously character- ized her periodic secretion. A careful examination of these clots would discover imbedded in them a rudimentary foetus. The long formed habit of nature, conjoined perhaps to too vigor- ous exercise, too stimulant food, or even mental emotions, caused the secretion to be continued as usual, and the ovum to be ex- pelled. These cases are generally considered to be simple monorrha- gia, and are treated accordingly. They rarely, if ever, result in farther difficulty. At a somewhat later period in gestation, when the ovum is from two to five or six months, abortion is very frequent, when the haemorrhage is alarming. These occur from various causes, and never without a cause which should be discovered by the physician, and the difficulty obviated afterward. This I wish most especially to have noted, that wherever there is a miscar- riage, THERE IS ALWAYS PRESENT SOME ACTUAL PERCEPTD3LE AND often tangible cause. In many cases this is easily known. Some injury, sudden fright, the effort of vomiting, has been sufficient to destroy the integrity of the ovum, and as a dead substance, as a foreign body, it has been expelled. This may occur as the effect of mercury, quinine, or other medicines, or the action of the uterus sympathetically stimulated by cathartics. Great fatigue may be the existing cause of the expulsive uterine action. But there are many abortions which have been con- sidered to be without cause. Females have aborted without any particular reason, every few months during many years, and the physician, in his ignorance of any cause, has stated that it was from the force of habit; that there was a tendency, from habit, of the uterus to throw off its contents upon the least irritation or excitement, when the ovum arrived at a certain maturity. Females have been made to believe, what the physician himself, once equally credulous, believed, that there was a " tendency to abort;" and have been made to lie in bed for weeks and months, made sick by want of air and exercise, to prevent a senseless organ, devoid even of the nerves of sensation, from yielding to the temptation or tendency to abort. 204 EVIDENCE OF THE SPECULUM IN ABORTION. Thanks to the added wisdom of the nineteenth century, we now know better than this. The new lights of science have added ocular evidence to the vain theories invented to conceal our ignorance, At the given period, or thereabout, the woman with the uterus having these bad habits, perceives that the usual vaginal secretion is slightly tinged with red, which by degrees deepens in color, till a decided haemorrhage, accompanied by pains in back, thighs, etc., with involuntary expulsive efforts, is the re- sult ; and sooner or later the foetus is expelled. If one examine the uterus, as far as may be done by means of the speculum, either before these symptoms commence, or after the abortion is completed, he will find that there is local disease of the os uteri, which is the fons et origo of all the trouble ; that there is uterine congestion, ulceration, or lesion of the epithelium, and enlarge- ment of the mucous follicles, or fissure of the os. Uterine congestion, as a cause of abortion, not unfrequently depends upon high-feeding—not too much in quantity, but too stimulating in its character upon the circulation. This is noticed in animals. Lewis S. Hopkins, M. D., says : " In the August number of the Farmer, complaints are made of abortion in cows. " High feeding has a direct tendency to produce this; if a cow has done so once, meal should be kept from her a month or two before the anticipated period of abortion, or during the greater portion of the period of gestation. Many a female of the human species has only avoided the same "mishap," by strict attention to diet. " Too high feeding, with no hard work, often produces an irritability not only of the nervous, but of the circulating system, in its minutest subdivisions, as spread over secreting surfaces. There is a greater tendency to this in the female system than in the male. The mare fed on oats, and but little used, will often become ex- cessively snappish, and intensely cross. Withdraw her oats, and she loses this irritability ; or give her hard work, and the effect will be the same. If in the cow this irritability of the secreting surfaces, induced by continued high feeding, is fed and fanned by meal and grain, a tendency to >nf'animation is produced in the ute- rus, which, during gestation, is the most irritable point in the system. Nature has no other way to relieve herself of this danger to the life of the mother, when the meal and grain continue to flow in, than to prevent inflammation of the womb, and death, by evacuating the contents of the uterus. The increasing irritability of that organ, excites its repeated contractions, as at the full period ; and abortion re- sults, and the mother is saved at the expense of the young. If the youn"- is carried to maturity, it survives, and the mother dies of inflammation of the womb." Ulceration or lesion of the epithelium and the enlargement of the mucous follicles, as the second cause of abortion, depends CAUSE OF OFT-REPEATED ABORTIONS. 205 somewhat upon the situation of the placenta. If high up at the . fundus of the uterus, unless the abortion be effected early, the current of blood is remote from the abraded surface, which is either healed by this derivative or remains in statu quo. Should the placenta be inserted lower down, the tendency to bleed is much greater and abortion more probable. In the greater majority of cases of abortion at the completion of a certain period, there is fissnrc of the os uteri. If we take the description of the changes of the os uteri during gestation, as formerly believed aud as still described in the books, we shall not be so well able to account for the fact that a fissure of the os produces abortion. But we take that given and demonstrated by M. Stolz, already stated on page 13S, proving that the change in the os uteri commences at the external os, and not at the internal os. Now we know that the vast majority of cases where fissure of the os exists, not only does it commence at the inferior extremity of the cervix uteri, but that in far the greater number it is con- fined to that portion. With this fact before us, and the knowledge that this same portion of the cervix, in the progress of gestation, first com- mences to soften and contract, we may easily see the heretofore unaccountable cause for numerous abortions. The softening renders the already irritated portion, to the vessels of which an unusual activity has been imparted, still more vascular. The subsequent contraction draws apart the sides of the fissure, ex- poses the orifices of the various vessels, a slight haemorrhage ensues, which gradually increases, till the life of the germ is destroyed, or the bleeding becomes so profuse as to stimulate the uterus to the expulsion of its contents, or to endanger the life of the mother. An abundance of such cases are given by Gooch, Dewees, and other writers, styled by them " irritable uterus," but in which the pathological changes were most un- doubtedly such as have been here described. This is not a fanciful theory, for which we seek for facts to substantiate, but, on the contrary, it is one deduced from facts. Numerous cases have occurred in my own practice, and in those of my friends, which I have been called to see in consultation. A few marked cases only will I relate, in a very brief man- ner, as illustrative. A lady, about thirty years of age, was con- 206 FISSURES OF THE OS IN ABORTION. •fined with her first child at full time, after a very severe labor of some days' duration. I saw her two years after, when she stated that she had never enjoyed a well day subsequently to this confinement. That she had nursed her infant about a year, constantly troubled by pain and weakness in the back and loins, accompanied by a more or less profuse, leucorrhoea. That lat- terly she had been much debilitated by repeated abortions, occurring from about the second or third month of pregnancy. They commenced by slight bleedings, increasing to a profuse haemorrhage, threatening her life. Vaginal digital examination discovered a marked prolapsus of the uterus when erect, but which subsided when in the recumbent position : the cervix im- mensely hypertrophied and ragged. A better investigation with the speculum disclosed the os, so immense as to be scarcely admitted between the fully distended blades of a four-bladed Ricord, divided into three irregular-sized lobes, the edges of which were covered with profuse, unhealthy granulations, the whole surface denuded of epithelium, and the entire organ bathed in a profusion of the muco-purulent secretion usually accompanying these lesions. The pase was a plain one. The os had been torn in those places at the first labor, and these lacer- ations, never healed, were a constant source of irritation, and, when pregnant, the undoubted cause of all the abortions, sub- sequently. I will mention but one more case further to substantiate the view which I have taken of this form of abortion. I lay more stress upon it, because these cases have been one of the oppro- bria of medicine; and having, as I think, given a conclusive proof of the theoretical cause of these affections, I wish now, by some cases plainly showing the facts, as sustaining the theory, and from which I have deduced the theory, to convince all of the correctness of this view, and to lead to a reformation in the past and present palliative and temporizing method of treat- ment. In the vast majority of these cases of irritable uterus, in nine out of ten, where there exists this periodical tendency to abortion, cure is not only possible, but if the treatment proper for the affection be employed, the cure is as certain as may be predicted in any disease that exists. If, however, the eyes are to be closed and the ear shut to the facts which the advance of science has revealed,—if, supine in our conservatism, we join CASE OF ABORTION. 207 with the blind old fogy-ism in its empty denunciation of the speculum uteri, and its immense utility in these affections,— dogs in the manger, we neither use it ourselves, nor permit others so to do,—worse than the most arrant quackery, which always proposes something new, and thereby sometimes igno- rantly benefits, we are content with the ashes of the past, instead of seeking for living fire in the present; if thus contented in our partial acquirement, there is henceforth no advance in science, and the unnecessary sufferings of millions remain unmitigated, unassuaged. But my object is not to'attempt to convince those " who see- ing see not, and hearing hear not, neither do they understand," but merely to state my own views, in all simplicity, and some of the facts upon which they are founded. A most instructive case, to which I refer in consideration of several views here presented, is the last reported by myself in the American Medical Monthly for October, 1854, entitled " Fifteen Selected Cases of Operative Midwifery." After two confinements at full time, the lady experienced a slight jar in stepping from her carriage. She was daily expect- ing her third confinement. Pains soon came on. She was speed- ily confined with a dead child. Two years subsequently she aborted at about the third month. This commenced with a slight discharge of bloody mucus, which was supposed by her medical attendant, and myself, to arise from fissures of the os, and the next day was appointed for making an examination, but before that time arrived she had aborted, and her life was in great jeopardy. When sufficiently recovered, some weeks after, from the excessive haemorrhage, to which reference will be subsequently made, her physician found, upon examination by the speculum, not only the local congestion to be expected after so'recent a confinement, but induration, and fissures apparently of long standing, and quite sufficient to account for all the diffi- culty she had experienced. I might quote scores of similar cases from experience in the Northern Dispensary, in the class of Diseases of Females, and I am entirely convinced in my opinion of the origin of the hitherto unknown or unsuspected causes of numerous abortions as pro- ceeding from local disease of the womb, and not to be described under the name of " irritable uterus," or any other vague and unsatisfactory appellation. 208 TREATMENT OF ABORTION. The treatment of these cases is of two characters, viz.: the im- mediate haemorrhage; and secondly, for the cure of the causes of the haemorrhage. When called early to a case of threatened miscarriage, when the haemorrhage is slight, and the symptoms indicate its local character, from ulceration or fissure of the os, a speculum exam- ination should be immediately instituted, and the parts, if found in this condition, cauterized by nitras argenti, thus temporarily arresting the haemorrhage, and the uterine plethora allayed by general bleeding, and the excitement quieted by an anodyne. Should this treatment be effectual, the disease of the os should be subsequently treated by local applications, until the parts are restored to their normal condition. If, however, the haemorrhage was not the primary symptom, or if the abortion was threatened in consequence of some fatigue, great exertion, or excitement, where there may be a debilitated condition of the uterus, which, in its relaxed state, opens the os, or in some way diminishes the circulation, and impairs its vital functions, I have found great benefit from the tonic effects pro- duced by small doses of secale cornutum. The slight contrac- tion consequent upon its action, closing the bleeding orifices, and frequently entirely arresting all further discharge and dif- ficulty. This point I have already fully stated with cases illus- trative, in an article entitled, An Essay on Ergot, with New Views of its Therapeutic Action / published in the New York Journal of Medicine for September, 1853. The cause of abortion will probably be allowed to be some- times from a debilitated condition of the organ containing the foetus. The relaxed state opens the os, or in some way dimin- ishes the circulation and impairs its vital functions ; the judicious administration of ergot improves its tone, invigorates it and prevents the threatening miscarriage. Ergot is not a medicine of the cumulative order, neither is it confined to single action. In small doses it does not produce the convulsive, evanescent contractions which accompany labor, but a slow molecular character, permanent and prolonged. If this local tonic is too freely administered, it passes on still further and then a too high stimulation produces, from an opposite cause, exactly the same result that was threatened by the previous debility. The bleeding in the cases I have mentioned, will rarely, if ever, be so great as to endanger life. If however, in a case ABORTION, OR PLACENTA PR.EVIA. • 209 where the origin of the flow is doubtful, it amount to any considerable quantity, the result will be to dilate the os, so that the finger may determine whether there be placenta praevia. If so, we should temporize, by resorting to perfect rest, external and internal applications of ice, alum internally,—a large piece passed into the vagina, and placed near the os uteri. These means will sometimes arrest the flow, to be repeated again at some future time. If, however, the patient be at the full time, or the miscarriage cannot be prevented, the next duty is to rupture the membranes, either through the presenting placenta by a small puncture, or, what is preferable when the placenta but partially covers the os, through the membranes at one side. Ergot should then be given in sufficient quantities to keep up a continued contraction of the uterus, and to thus force the pre- senting portion of the child firmly down upon the bleeding surface, and thus to dam up the flowing stream. In this man- ner the head forms a natural tampon. If this be not successful, manual interference must be had recourse to, and the hand passed through or by the side of the placenta, and the child turned and delivered as speedily as may be. In some cases the vaginal tampon may be found advantageous, but rarely in this form of trouble, when the child be d terme ! and in general it will be found but a temporizing method of doubtful utility. When, by any accident, we have a detached placenta, the case is indeed a grave and startling one, calling for great decision and promptness of action. It resembles rupture of the uterus, in many of its symptoms, and is often extremely hard to diagnosti- cate. The fluttering pulse, anxiety of countenance, restlessness, retrocession of the presenting portion, exist, as in rupture. In general, however, the pear shape of the uterus is retained. For- tunately, the duty of the accoucheur is alike in each case. Im- mediate delivery is imperative. From the prostration from the loss of blood, there is no rigidity of the os to interfere with the introduction of the hand, and the immediate delivery by turning may be effected, if the head has so far retreated as to prevent the delivery by the forceps. I have seen but a few cases of this form of difficulty, and speak, therefore from a limited ex- perience. There seems, however, to be no other feasible man- ner of operating when these appalling accidents occur.] 14 LECTURE XIII. DURATION OF PREGNANCY. Gentlemen :—The question of the Duration of Pregnancy, involving, as it does, the Cause of the Coming-on of Labor, is one of the most interesting amongst the yet unsettled problems of Obstetrics. It is impossible to rest satisfied with the pious say- ing of Avicena, that, " at the appointed time labor comes on by the command of God," and we are impelled to attempt the pen- etration of a mystery, which has been the subject of numberless theories and speculations, but which has hitherto baffled all attempts at its satisfactory solution. It may be said that at the present time obstetricians and physiologists are pretty nearly divided between two opinions, as to the time of the duration of gestation and the circumstances which influence its termina- tion. According to one view the uterus is excited to expel its contents by the maturity of the foetus and its membranes. Upon the second hypothesis, the gravid uterus, like the unimpregnated organ, is ruled by the catamenial periodicity, and labor comes at what would have been a catamenial period, had the woman remained unimpregnated. Both these ideas, in a more or less perfect form, are of a very ancient date. Harvey, for instance, taught that parturition came on at the tenth menstrual period after conception. Harvey's master, Fabricius, and still earlier authorities, held that labor came on in consequence of the matu- rity of the foetus. In my work on " Parturition," I have adhered to the former view, and attempted to show that the ovaria are the organs which excite the uterus to the act of parturition. While doing this, I have dwelt upon the maturity of the embryo at the time of labor, and urged it as a manifest instance of the harmony of Nature, that the foetus should be perfectly developed, and the placenta and membranes showing signs of unfitness for their functions, when the ovaria excite the uterus to expel its 210 THE DURATION OF PREGNANCY. 211 contents. I shall, however, on the present occasion state as impartially as I can the facts which support, or tell against, either theory. The first thing which merits our attention in this inquiry is the statistical tables constructed by those who have kept regis- ters of large numbers of cases. The late Dr. Merriman made a very careful investigation into the duration of pregnancy, which has been quoted by almost all subsequent writers on the subject. He reckoned from, but without including, the last day of the last catamenial period, and he gives a table of 150 mature births cal- culated in this manner. Of these— 5 were delivered in the 37th week. 16 " " 38th " 21 " " 39th " 46 " " 40th " 28 " " 41st " 18 " " 42d " 11 " " 43d " This variation is very considerable, and the question suggests itself—In the case of the fifty-seven women who carried the ovum beyond the fortieth week from the last menstruation, was the gestation protracted beyond the usual time, or was it that conception occurred one, two, or three weeks after the last cata- menial appearance ? To these questions we shall have to revert hereafter. Dr. Murphy has given a table of 182 cases, in which the results were somewhat different from those obtained by Dr. Merriman. In Dr. Murphy's cases, the numbers delivered in the 40th and 42nd week were equal, twenty-five in each week; while in the 41st week, thirty-two labors occurred. The late Dr. James Reid, in an elaborate essay on the Duration of Human Pregnancy, begun in 1850, and completed in The Lan- cet in 1853, gives a table of the duration of pregnancy in 500 cases calculating from the last day of menstruation. Of these— 23 were delivered in the 37th week. 48 " " 38th " 81 " " 39th " 131 " " 40th " 112 " " 41st " 63 " " 42d " 28 " " 43d " 8 " " 44th " 6 " " 45th " 212 DATE OF CONCEPTION AFTER COITUS. These results prove, as in Dr. Merriman's table, that, calculat- ing from the last day of the last catamenial period, considerable variations in the duration of pregnancy occur. Is there more regularity in cases where the duration of gestation, or the date of the occurrence of labor, is calculated from the time of a single coitus ? Before entering upon this topic, it must be premised, that in the case of the catamenia frequent mistakes are made by the most careful women respecting the time of its last appear- ance. Errors, intentional or unintentional, are still more likely to occur in fixing the time of the coitus which has resulted in impregnation. Many of these cases occur in unmarried women,, in whom there is a very constant tendency to declare that the fruitful coitus has been a solitary one. Dr. Reid, in the paper referred to, collects forty-three instances of conception after single coitus, all of them resting upon testimony as credible as can be obtained in these cases. 260 days after single coitus, delivery occurred in 1 263 " " " 1 264 " " " 2 265 " " " 1 266 " " " 2 270 " " " 1 271 " " " 2 272 " " " 3 273 " " " 1 274 " " " 7 275 " " " 2 276 " " " 5 278 " " " l 280 " " " 3 283 " " » 2 284 " " » i 286 287 291 293 296 300 1 2 1 2 1 1 43 Thus it will be seen from this table that the average duration of gestation, reckoning from a single coitus, is about 275 days. But in this mode of calculating the term of gestation, variations quite as great as those wiiich occur in calculatinc from the cata- menial periods are met with. Dr. Reid, who wrote with a TABLES OF COMPARATIVE GESTATION. 213 desire to show that the duration of pregnancy should be calcu- lated from the time of impregnation, rather than from the last menstruation, was obliged to conclude as follows : " If we allow of a range from two to six days after menstruation as elapsing probably before conception takes place, it will then appear that about the thirty-ninth week after impregnation is more probably the ordinary duration of pregnancy, and this will coincide with the results of the table taken from cases of single coitus." This means that we can calculate as well from the date of the last catamenia, as from the date of conception, but that in one case we must reckon thirty-nine, in the other forty weeks. Upon which- ever basis we make the calculation, it is proved that the duration of gestation varies considerably, within certain limits, and we must look to other evidence than that derivable from such tables, to show the real cause of the termination of pregnancy, and the occurrence of parturition. In animals, where the date of coitus can be ascertained with greater accuracy than in the human female, the same variations in the time between impregnation and parturition in different females of the same species are found to exist. Thus the chief facts educed from these statisti- cal data, are, that, in a large proportion of cases, gestation ter- minates at a certain time, within the limits of a few days, and that this time bears pretty nearly the same relation to the cata- menial dates, as the dates of fruitful coition. Dr. Reid's is the largest cases of conception from single coitus which has been made, and the result yields the 275th day as the average time for the occurrence of labor. In the calculations from the cata- menial dates, Dr. Reid's cases give the same result as those of Dr. Merriman, the average time of the coming on of labor being the 40th week from the termination of the catamenia. If we get two cases of pregnancy in women in whom the cata- menia appeared at the same time, the date of parturition may vary within certain limits. The same variation occurs in the cases of two females to whom impregnation occurred at the same time. If we look to the results obtained from the observa-( tions made upon comparative gestation, the same variation of the duration of pregnancy, as calculated from the date of intercourse, is found; and in animals the utmost accuracy as regards dates can be procured. Baron Tessier found that the average duration of pregnancy in 160 cows was nine months 214 AGE OF PARENTS INFLUENCING LENGTH OF PREGNANCY. and ten days ; but of this number 68 went beyond the 280 days, in 20 gestation lasted 300 days, and in 5 instances it was pro- tracted to 305 days. The late Earl Spencer had the duration of gestation accurately noted in 764 cows. Pregnancy lasted on the average 285 days. In 8 cases only was this period exceeded by more than 12 days, and only one went 18 days beyond this time. These results differ somewhat from those of Tessier, but there are no grounds for questioning the accuracy of the observations in either case. Other observers have found the same variations in the gestation of the cow. Similar variations have been observed in-the gestation of mares, and in elephants; and in the smaller animals, where gestation lasts a shorter time, notable variations in the time of coming on of parturition are found to occur. The last hypothesis respecting the variable duration of pregnancy is that advanced by Dr. Clay, of Manchester, who argues from cases which have occurred in his own practice, and the facts known respecting the duration of gestation in animals, that the younger the parent the shorter is the term of gestation. Dr. Clay believes that the ages of both parents influence the duration of pregnancy ; but dwells particularly upon the influ- ence of the mother. There is a class of cases not hitherto noticed, by which the •duration of pregnancy from the time of coitus may be ascer- tained with considerable certainty. In 1851, Mr. Coleman, of Surbiton, drew my attention to the following circumstance: Two ladies, patients of his, were married on the same day, and both were delivered within ten hours of each other. The mar- riage took place on the 7th of May, 1850, and one was confined on the afternoon of February 8th, 1851, and the other at two a.m., on the 9th, or 276 days from the date of marriage. Both had menstruated a few days before marriage. I have collected a good many cases of this kind, and they show that in the majority of those in whom labor occurs within the forty-first or forty-second week from marriage, the deliveries occur before, rather than after, the 280th day from marriage. It is usual for marriages to take place shortly after a catamenial period, and the inference is, that in these cases impregnation must have occurred within a few days after marriage. Such cases tend to confirm the table of Dr. Reid, in which the average duration of labor was 275 days from the date of coitus. They do not, how- MALES THE RESULT OF LONG GESTATION. 215 ever, bear distinctly upon the determining cause of labor, and probably no mere statistics will ever settle the question. I now proceed to state the arguments in favor of the maturity of the ovum as the exciting cause of parturition. Those who consider the maturity of the foetus to be the cause of labor, point to the periodicity observed in the growth or flowering of plants, the separation of ripe fruit from the stalk, the leaf from the stem, the regularity with which the young birds are hatched from the shell, the regular appearance and shedding of the teeth, and similar phenomena of growth and development, as favoring the idea that the foetus separates from the womb, and excites the phenomena of parturition, in consequence of an inherent periodicity occurring as part of the development of the embryo. Dr. Carpenter refers to the pla- centa as the organ upon which the contraction of the uterus depends. He draws an argument in favor of this opinion from the phenomena of superfcetation, in which one child is detached from the uterus, a second remaining undetached, apparently in consequence of the immaturity of the placenta. Dr. Simpson has advanced the opinion, that " the loosening or decadence of membranes and placenta from the interior of the uterus consti- tutes the determining cause of parturition ; and that this loosen- ing or decadence is itself the result of the effete degeneration of the structure of the decidua towards the full term of preg- nancy." In the observations of Lord Spencer, it was found that gestation with males had a tendency to continue a few days longer than gestation with females. There is a popular belief that this occurs in the case of males in the human subject. In our fishing towns, where the dates of the absence of the husband are known, it is said that when gestation is prolonged beyond the usual term, a boy is expected, and that this expectation is generally fulfilled. Lord Spencer also found that cows in calf by a particular bull had a tendency to go a few days longer than those impregnated by other bulls in the herd. Those who oppose the view that the catamenial dates rule the duration of pregnancy, ask why parturition should occur at the tenth rather than at the eleventh or any other menstrual period ? But this may be replied to by other questions—why, for instance, should the catamenial period, as the rule, consist of twenty-eight days? or why should puberty come on at a particular age ? The only • 216 REGULARITY IN MENSTRUATION AND GESTATION. answer is, the fact that these particular periodicities do occur. In animals the periodicities of oestruation are little known, particularly in the wild state, but it is asserted that the larger animals do not cestruate sufficiently often to render it pos- ble that in their case the duration of gestation can be a multiple of an cestrual period. There is one point which has already been adverted to in con- nection with menstruation, and which is supposed to militate against the ovarian theory of the cause of labor. As the rule, we have seen that the menstrual periodicity recurs every twenty-eight days ; but in some women the period returns a day or two earlier or later than this with considerable regularity. Others are regular every fortnight, or every three weeks; or the period returns only every five or six weeks. What multiple of the catamenial periodicity is observed in such cases ? I have carefully noted all the cases I have met with of this kind, and I find that in such women the duration of pregnancy is more irregular than usual. The future collection of such cases will be very valuable in elucidating the true cause of labor, far more so than cases in which the last date of menstruation and the occur- rence of a single coitus are recorded. It is said by some who oppose the ovarian theory, that if the ovarian or catamenial periodicity ruled the coming on of labor, the date of parturition should always be exactly 280 days from the last menstruation. This is hardly a valid objection, inasmuch as in the most regular females, the catamenia often appear a few days before, or a few days after, the expected time, yet no one on this account refuses to accept the ordinary monthly periodicity as the rule amongst women. The irregularities in the duration of gestation are cer- tainly not greater than the irregularities observed in menstruation. The argument in favor of the ovarian influence, as a determining cause of labor and as regulating the duration of pregnancy, has now to be stated. It is allowed by all observers, that labor has a tendency to occur, and does occur in a great proportion of cases, in the fortieth week from the last menstruation ; and it is equally al- lowed, that impregnation has the tendency to happen just after the catamenial period. It is also made out by the record of a consider- able number of cases, in which a single coitus occurred, that gesta- tion lasts, on an average, about 275 days from the actual date of impregnation. These data make the average duration of preg- • OVARIAN INFLUENCE IN GESTATION. 217 naucy approach 280 days from the last catamenial period, so that the time between the last catamenial period and the occurrence of parturition is on the average, very nearly a multiple of a single catamenial period. This is a curious coincidence, even if it were proved that the uterine function of parturition was quite inde- pendent of the ovarian influence. But we know that the uterus performs some of its most important functions under the influence and control of the ovaries. It is allowed, even by those who deny the influence 01 the ovaria upon parturition, that the catamenial function is ruled by the ovaria, that the ovarian phenomena may occur without menstruation, but that menstruation never occurs without the influence of the ovaria. It is admitted by almost, I think I may say all, practical accoucheurs, that the influence of the ovaria are felt during pregnancy, that women feel uneasiness at the cata- menial dates, and are more liable to abort at these times than at others. This is particularly the case with women who have suf- fered from dysmenorrhoea previously to pregnancy. In certain cases of extra-uterine gestation, as, for instance, in abdominal pregnancy, the development of the foetus has frequently gone on to the usual limit of pregnancy, when violent pains, as of labor, and contractions of the enlarged uterus, have come on. Dr. Ramsbotham observes on this point: " It is a curious circum- stance in the history of these cases, that if the child should live till the term of gestation is completed, as soon as that time has expired, the uterus takes on itself expulsive action, which is at- tended with pain similar to the throes of labor ; and, during these pains, the deciduous membrane is expelled from the cavity with more or less sanguineous discharge." Cases have been not unfrequently met with in which the ovum has been blighted in the middle part of pregnancy, and in which the decidua and chorion have been diseased ; but the mother has carried the dis- eased ovum for a considerable time, or to the natural limit of gestation, when the molar or degenerated ovum has been expelled. There is another class of cases in which twin gesta- tion is proceeding; but one ovum dies, yet the uterus is not excited to contract, but the dead and living ovum go on to the full term. In cases of superfcetation, when one living child has been born and birth has been given to the second some time sub- sequently to that of the first, I have found that there is a ten- 218 CASES OF 6UPERFCSTATION. dency to some multiple of the catamenial period in the inter- val between the birth of the two children. Dr. Fleetwood Churchill has given an account of the three most remarkable cases of superfcetation on record ; and I proceed to an analysis of these cases, quoting the words of Dr. Churchill: "In the 'Recueil de la Societe d'Emulation,' there is the case of M. A. Bigaud, of Strasbourg, aged thirty-seven, who was delivered of a living child on the 30th of April. The lochia and milk were soon suppressed. On the 17th of September of the same year (i. e. about four months and a half after the first delivery) she brought forth a second apparently mature and healthy child." The first labor occurred on the last day of April, so that we have the thirty-one days of May, thirty days of June, thirty-one days each of July and August, and seven- teen days in September—in all, one hundred and forty days from the first to the second birth, or exactly five catamenial periods, 5 x 28=140. In a case related by Desgranges, of Lyons, to con- tinue the account of Dr. Churchill, " the woman was delivered on the 20th of January, 1780, of a seven months' child, and on July 6th, 1780, five months and sixteen days after the former birth, she gave birth to a second, which had apparently reached its full time." In this case we have eleven days in January, twenty-nine in February (it being leap-year), thirty-one in March, thirty in April, thirty-one in May, thirty in June, and six in July, between the two births, in all one hundred and sixty-eight days, or precisely six catamenial periods, 6x28=168. The third case noted by Dr. Churchill is as follows, from the account of the late Dr. Maton, in the fourth volume of the "Transactions of the College of Physicians " :—" Mrs. T----, an Italian lady, but married to an Englishman, was delivered of a male child at Palermo, November 12, 1S07. On the 2nd of February, 1808, not quite three calendar mouths after the preceding accouch- ment, she was delivered of a second male infant. Dr. Maton assured Dr. Paris that' both the children were born perfect;' the first therefore could not have been a six-months' child." If we include the day on which the first child was born, the time between the births amounts to eighty-three days, or within one day of three periods of twenty-eight days. In these cases it is impossible not to recognize the close adherence to the ovarian periodicity, and it is difficult to imagine that this could be a EXPERIMENTS UPON THE OVARIES. 219 mere coincidence. All such facts militate against the supposi- tion that the irritation of the uterus by the mature foetus and its membranes induces labor; and support the view that it is excited by extra-uterine and ovarian influence. There is also another class of facts which tells against the hypothesis that labor depends solely upon the maturity of the foetus and the pla- centa and membranes, and, as a consequence, in favor of the ovarian periodicity. Instances are frequently met with in which the placenta becomes prematurely mature and caducous, or affected with degeneration, and the child dies in utero shortly before birth. It is well known that in certain women this hap- pens many times in succession, the placenta becoming ripe, and. positively unfit for the performance of • its functions, without exciting the uterus to expel its contents. It is difficult or impos- sible to account for such cases on the supposition that the mature ovum excites the uterus to the efforts of labor. It is not that there is any special adhesion of the placenta and membranes to the uterus in these cases ; for if the foetus lives in a feeble condi- tion up to the time of labor, it separates from the uterus with the first pains, and causes the death of the child. On the other hand, labor comes on just as regularly in cases in which the pla- centa has adhered so firmly to the uterus, in consequence of inflammation, as to require mechanical detachment after labor. In 1850 I performed some experiments, with a view to deter- mine the possibility of exciting the uterus to contraction by irritating the ovaria. In these experiments I had the valuable aid of the late Mr. Henry Smith, who assisted Dr. Marshall Hall in his great course of experimental inquiry. We found that in the gravid rabbits chloroformed, and with the abdomen laid open, irritation of the ovaria by galvanism, a heated needle, or pinching with the forceps, excited distinct contractions of the uterus and vagina. In the rabbit at the middle period of gesta- tion, after a few contractions of the parturient canal had been excited artificially by irritation of the ovaria, the intermittent contractions of ordinary parturition went on until the foetuses were expelled, artificial parturition being thus excited by ovarian irritation. Berthold experimented upon animals during gesta- tion by extirpating the ovaria, and found that this operation invariably led to abortion. 1 have heard that Dr. Simpson a 220 RESULT OF EXPERIMENTS ON THE CAUSE OF LABOR. few years ago performed some experiments with a different result from those of Berthold, but I believe these experiments have not been published. In my work already referred to, I have shown that in many of the lower animals, ovulation and oestruation are going on at the time of parturition, and that many of them admit the male, and conceive again on the same day that the uterus has been emptied. I have thus advanced, and I trust impartially, the arguments and facts for and against the theory of the ovarian cause of labor, which I believe I was the first to propound. I have for many years taught that the ovaria, acting at, or near the tenth period from the time of the ovulation which has ended in im- pregnation, excite in the uterus those changes which lead to the expulsion of the ovum. I have also compared the show which accompanies parturition, and the lochial discharge which follows it, to the menstrual discharge. It has appeared to me, that the changes in the uterine portion of the membranes are similar to the changes which occur in menstruation, and that the contrac- tions of the uterus resemble those more imperfect contractions which occur in many women at the catamenial periods, and which we do not hesitate to refer to the ovaria. I believe there are some facts which do not admit of explanation upon the sup- position that the cause of labor depends on the maturity of the ovum ; as, for instance, the occurrence of uterine contractions at the end of gestation in cases of extra-uterine fcetation. I believe, on the contrary, that as to the facts which appear to militate against the ovarian theory, most of them admit of explanation. In a practical point of view, we may consider that the aver- age duration of pregnancy is about 280 days from the date of the last catamenia, or about 274 or 275 days from the time of coitus, when this can be ascertained. As the date of fruitful intercourse can only be known in rare and exceptional cases, we are compelled to date from the last catamenia,—the point which, from time immemorial, has been the foundation of the calcula- tions of women and their attendants. I constructed the periodoscope upon the data that conception generally occurs a few days after the completion of a catamenial period, and that labor may be expected on some day of what would have been the tenth period, had pregnancy not intervened. I have now PERIODOSCOPE. 221 for some years used this instrument in practice, and found the results generally correct. It is at the same time a mode of cal- culation and a diagram of pregnancy. Those who calculate from the last menstruation and those who date from conception, may equally use the periodoscope. The cases in which the date of fruitful coitus can be known are rare, and for practical purposes the few days succeeding the last menstruation may be taken as the date of that event. Five days after the last menstrual date are marked in the following diagram as the time within which conception generally takes place:— Fig. 59. PARTURITION Diagram of the Periodoscope. 222 OBSTETRIC READY RECKONER. [The following table is much in use in the United States.:— TABLE FOR CALCULATING THE PERIOD OF UTERO-GESTATION. NINE CALENDAR MONTHS. From To Days. Jan'y 1 Sept. 30 273 Feb'y 1 Oct. 31 273 March 1 Nov. 30 275 April 1 Dec. 31 275 May 1 Jan'y 31 276 June 1 Feb'y 28 273 July 1 March 31 274 August 1 April 30 273 Sept. 1 May 31 273 Oct. 1 June 30 273 Nov. 1 July 31 273 Dec. 1 August 31 274 The above Obstetric " Ready Reckoner" consists of two columns, one of Calendar, the other of Lunar months, and may be read as follows:—a Patient has ceased to menstruate on the 1st of July; her confinement may be expected at soonest about 31st of March, {the end of nine Calendar months) / or at latest, on the 6th of April, {the end of ten Lunar months.) Another has ceased to menstruate on the 20th January; her confinement may be expected on the 30th September, plus 20 days, {the end of nine Calendar months) at soonest; or on the 7th October, plus 20 days, {the end of ten Lunar months) at latest.] TEN LUNAR MONTHS. To Days. Oct. 7 280 Nov. 7 280 Dec. 5 280 Jan'y 5 280 Feb'y 4 280 March 7 280 April 6 May 7 June 7 280 280 280 July 7 August 7 Sept. 6. 280 280 280 LECTURE XIY. MOLAR PREGNANCY—BLIGHTED OVA. Gentlemen :—Certain matters are occasionally discharged from the virgin or impregnated female, which it becomes neces- sary to distinguish from the results of fecundation. These con- sist of masses of squamous epithelium from the vagina, fibrin- ous collections from the cavity of the uterus, and the membran- ous product expelled in some cases of dysmenorrhoea. There can be no difficulty in deciding on the flakes or tubular pieces of squamous epithelium, exfoliated from the vagina. The fibrinous masses expelled from the uterus resemble an almond in size and shape, being to some extent casts of the uterus ; they are smooth externally, and possess a very imperfect central cavity. The dysmenorrhoeal product consists of the uterine mucous mem- brane, exfoliated in a more or less perfect form. When entire, it has the shape of the cavity of the body of the uterus, is rough externally, and smooth within, having a distinct triangular cavity, with two openings above, and one below, at the sites of the Fallopian tubes and the canal of the cervix uteri. There are of course, no traces of funis, membrane, or foetus. Examin- ed microscopically, the squamous epithelial masses consist of quantities of epithelial scales ; the fibrinous masses are com- posed of filaments of fibroid material arranged in bands, and myriads of grandular corpuscles, similar to exudation cor- puscles ; in the true dysmenorrhoeal membrane, the convoluted utricular glands are found with their openings on the smooth internal lining of the cavity, and ccecal extremities of the glands upon the rough or external surface. The older writers included polypi and fibrous tumors in the list of moles ; but the above constitute what are now considered False or Spurious Moles. The Genuine Moles, which are the result of impregnation, are of various kinds, consisting of different forms of degenera- ' 228 224 WHAT ARE MOLES ? tion of the membranes of the ovum. We can readily distin- guish the varieties of mole depending on the carneons or fleshy, hydatiginous, and the fatty and other degenerations of the •anes. None of these cases can occur without conception. great confusion prevailed upon this subject. Many ved that fleshy moles might occur in nuns and others ■> virgins, without the occurrence of intercourse. 1 Hat hydatids were independent animals, and that was compatible with the purest chastity. Denma. sometimes originated in the uterus as independe. id Sir Charles Clark was of opinion that uteri' .it exist apart from pregnancy. Cases are recc .1 uterine hydatids have been retained long be .al period of gestation. Madame Boivin, Baude1 1, Desormeaux, and Velpeau, are quoted by Dr. V ; as being in favor of the belief that this form of d' jvum may be retained for many months or eve- .• the ordinary date of labor. I am not aware tin" t case of this kind has been observed. The ten- d' . modern research, however, has been to demon- p e genuine mole cannot occur except as the result of n, and as the degeneration of a true ovum. In some l twin conception, one foetus has disappeared under ice of hydatiginous degeneration, while the other has ■ ■ ■ 1 healthy up to the full term. It is related of the ed Beclard, that he was born under these circum- en an ovum is rendered unfit for continuing the develop- ment of the embryo in the early weeks of gestation, by the effusion of blood between the membranes, or into the substance of the cliorion, or by other disease of the membranes, it may not be expelled at the time, but remain in utero, and undergo the changes which constitute carneous degeneration ; or there may be a partial separation of the ovum from the uterus, fol- lowed by an attempt to repair the mischief by the reunion of the separated portions. The fibrin of the effused blood becomes pale and semi-organized, and a perverted nutrition of the mem- branes goes on. The diseased membranes increase in bulk but become dense, and quite unfitted for the development of the foetus, which remains of the same bulk as when the effusion or CARNEOUS DEGENERATION OF THE OVUM. 225 separation commenced, or it may become atrophied. This may continue for three or four months, until at length the degene- rated ovum is expelled, consisting of the nest-like membranes and a small embryo of two or three weeks' growth, or in some cases the foetus may have disappeared, and traces only of the umbilical cord remain. Such are the main points connected with carneous degeneration of the ovum. It has often been pointed out that such cases are of considerable importance in a medico-legal point of view. A husband, for instance, may have believed his wife pregnant, and after his absence from home for several months she may abort on his return, of a foetus so min- ute as to give rise to a suspicion of her fidelity, unless such a matter could be explained by the death, retention, and degene- ration of the ovum. Fig. 60. Blighted Ovum with Carneous Degeneration of the Membranes. The next form of embryonic degeneration to be considered, is the hydatiginous variety. The latest and best account of hyda- tiginous degeneration of the ovum is that by Dr. Barnes, in the British and Foreign Medico-Chirurgical Review, contained in the volume for 1855. In this article, the origin of the disease from the perverted growth of the villi of the shaggy chorion is 15 226 WHAT ARE HYDATIDS ? very clearly traced. When treating of the cliorion and pla- centa, we have described the clavate villi of the chorion, and the layers of cells which they contain. These villi increase by a process of gemmation or budding, very similar to the growth of the roots of a tree. From the sides of one villus, other villi, by a process of cell-growth, sprout out, and from these, in turn others arise. Under normal plastic influences, a due pro- portion is preserved between the increase of the nutrient and depurative powers of the chorion and decidua, and the requirements of the enlarging embryo. But it sometimes happens that this growth of the villi is abnormal, and the cells they contain increase in size, and become dropsical, consti- tuting the hydatiginous degeneration of the ovum. The hyda- tids themselves, in the recent state, are full of transparent fluid, and are either round, pyriform, or oblong in shape, the size of the vesicles varying greatly. Some of them are borne upon pedicles, others are growing from the walls of larger hydatids. Mr. Paget, following Mettenheimer, has pointed out that, on the walls of the primary vesicles, buds appear and develop into separate hydatids, just as the buds protrude from the healthy villi, to produce, by normal growth, new villosities. The pedicles of those hydatids, which appear stalked, are formed of the remains of the base of the villus at the expense of which the hydatid has been formed. As a rule, the activity of the growth and the increase of the villi are, Dr. Barnes observes, greatest in early pregnancy, and it is at this time that the hydatiginous degeneration is most prone to occur. Drs. Rams- botham and Montgomery believe that small portions of placenta, retained in utero after parturition at the full term, may become the nucleus of hydatiginous formations ; bnt Dr. Barnes com- bats this view, from the general history of hydatiginous forma- tions, and the destruction of the fcetal vessel of the placenta, which occurs at the time of birth. This question is a very inter- esting one, and must be considered as unsolved. Ko doubt, the tendencies to the formation of hydatids diminish with advancing pregnancy, but it is not clear that there is any difference between a portion of placenta adherent to the uterus after labor at the full term, and the whole placenta adhering to the uterus after the death of the foetus, but without exciting the expulsion of the ovum. This form of degeneration frequently commences * GROWTH OP HYDATIDS. 227 at a very early date of gestation, and the destruction of the embryo is much more complete than in the fleshy variety of mole. Growth is limited to the cliorion and the diseased villi, so that all traces of the foetus generally disappear, the uterus being filled with a mass of hydatids, of various sizes. The uterine hydatids were compared by Gooch to currants, and by Cruveilhier to a bunch of grapes. Dr. Barnes quotes the objections of Mettenheimer to the comparison of Cruveilhier, and gives the description of Mettenheimer himself. This accurate observer considers the chorion, which is itself a large vesicle or bladder, as the centre of the whole growth. On the walls of this great vesicle, a new generation of cysts is formed, and each of these cysts has the power of producing one or many daughter cysts; or, to use his precise words, "Berry grows out, of berry, and the stalks do not unite berries with the principal steins, but berries with berries, and, lastly, with a central mother Fig. 61. Portion of an hydatid Mass. cyst." This arrangement of the vesicles is very well shown in the above engraving of a portion of a mass of hydatids, from a preparation of Mr. North, in St. Mary's Hospital. In the 228 FOETUS FLATTENED BY PRESSUKE. patient furnishing this preparation, enormous quantities of hyda- tids were expelled at the fifth month, the symptoms being alter- nate haemorrhage and watery discharge. In the third form of degeneration, occurring at a later period of gestation, the placenta may become so diseased as to be unfitted to carry on the nutrition of the foetus, or the foetus may die, or be destroyed by disease of the cord without in either case inducing separation of the placenta from the uterus. The nutri- tion of the placenta may go on more or less imperfectly, and the foetus under these circumstances, becomes shrunken and atten- uated to an extraordinary degree. It sometimes occurs that this is the case in twTin gestation. Indeed, it seems more prone to happen in twin than in other cases. It may then occur that the shrivelled foetus may be expelled at some period of pregnancy, the uterus retaining the other to the full term, or the shrivelled and the living embryos may be retained together, and the woman delivered of a full-grown foetus and one of two or three months at the full term. Such cases are often confounded with cases of superfcetation. I once attended a patient in a delivery at full term, who, four months before, had aborted while return- FiG. 62. Blighted Ovum, with Carneous Degeneration of the Membranes. ing from the West Indies. Dr. Simpson has pointed out, that when the dead foetus is retained with a living twin, it becomes flattened by pressure between the living ovum and the uterus of SYMPTOMS OF MOLAR PREGNANCY. 229 the mother. Dr. Barnes is of opinion that ill fatty degenera- tion, of the placenta to such an extent as to destroy the embryo, two or three weeks from the death of the foetus is the usual time within which the uterus is excited to expel its contents; but I have seen one well-marked cause of fatty degeneration, in which the foetus died at the fourth or fifth month, but was not expelled until the full term. It is in the highest degree proba- ble that in all cases of death and retention of the ovum, after the formation of the placenta, the retained membranes become the subject of fatty degeneration, and that this also occurs to a considerable extent in what are are called fleshy moles. The symptoms of molar pregnancy vary considerably in the different forms of this disease. In the carneous moles there is an arrest of the breeding symptoms, and the patient remains out of health. The ovum, from the time of its death, becomes to a great extent a foreign body, and is a source of irritation to the system generally. No increase of size takes place, so that, at the fourth or fifth month, the uterus may not be larger than it should be in the fifth or sixth week of normal pregnancy. The complexion is muddy, and the breath foetid, with loss of appetite and digestion. Haemorrhage frequently occurs as the degenera- tion of the membranes proceeds, but not to any great extent, on account of the small size of the uterus. There is sometimes a constant sanious discharge, in which case the health suffers more than usual. But in many of these cases, the symptoms, it must be confessed, are very obscure. This is because the death of the ovum occurs before the symptoms of pregnancy assume a positive form, and while the uterus is comparatively undeveloped, so that there is a considerable resemblance between these early moles, and the mixed cases of amenorrhcea and monorrhagia met with in practice. In the hydatid mole, the symptoms are more strongly marked than in the fleshy variety. When the ovum has taken on the hydatiginous form of degeneration, the increase is often enor- mously rapid, so that at the fifth or sixth month the abdomen is as large as it should be at the end of pregnancy, or even larger. The shape of the uterus is frequently altered from the usual pyri- form outline, its growth extending laterally on both sides; or it becomes irregular in form. With the marked increase in size, there is the absence of all foetal movements, and of the sounds of 2oO SYMPTOMS OP HYDATIDS. the foetal heart, combined with a dense uterine tumour. There is frequently also, after the three or four months of suspension of the catamenia which attends pregnancy, a copious discharge of water and blood, or of water slightly tinged with blood, resem- bling red currant juice. This occurs at irregular intervals, and in variable quatities. The watery discharge is accompanied by pains, and appears to be caused by the breaking down of num- bers of the larger hydatids. These symptoms are sufficient, in most cases, to make the nature of the affection plain. In a sus- pected case, the discharges should be carefully examined, and, of course, the detection of a single hydatid, or of a portion of an hydatid, renders the diagnosis certain. Little information is acquired by digital examination in cases of hydatid mole, when the degenerated mass remains altogether within the uterus. But the other cases in which a discharge similar to that commonly met with in hydatids occurs, are cauliflower excrescence, and certain cases of polypus, in which the disease can readily be made out by examination. The loss of health caused by hydatids is often of the gravest character, from the quantity of watery and sanguineous discharge. Owing to the extensive attachment of the hydatid mass, its separation is sometimes attended by flood- ing equal to that met with in placenta-prsevia. Profound anaemia, failure of the heart's action, dropsical swellings, and even paralysis, have occurred in the course of this disease. Sometimes masses of hydatids are discharged from time to time; but portions of the diseased structure being left behind, the growth goes on afresh, and reduces the patient to the great- est extremity of weakness. Two or three wash-hand-basinfuls of hydatids have been expelled from the uterus at once in some cases. The moles occurring later in pregnancy, or in which simple shrinking of the foetus and degeneration of the placenta occur, have their special symptoms, and may, with care, be recognized by the attendant during their progress. As in the other form of mole, there is a recession of the ordinary signs of pregnancv. There is also an arrest of increase, and a positive diminution of size in the abdomen. The auscultatory signs of the livino- foetus are altogether wanting. Either quickening does not occur, or after having been felt, the movements of the child cease. Peris- taltic actions of the uterus may occur, but these can readily bo REMOVAL OF HYDATIDS. 231 distinguished from the movements of the foetus. Haemorrhage generally occurs as the degeneration of the placenta, and its partial separation from the uterus, goes on. The loss of blood may be constant and slight; or it may occur occasionally, and to a considerable extent. This depends on the successive separa- tion of portions of the placenta in consequence of disease, and the irregular contractions of the uterus. In this form of a re- tained ovum, as well as in the fleshy mole, there is frequently a disagreeable discharge, and the health of the patient becomes greatly deteriorated by the irritation of the dead mass, the loss of blood, and the poisoning of the circulation by the absorption of foetid material. The treatment of molar pregnancy consists in emptying the uterus of its diseased burden, and in supporting the strength of the patient, and warding off accidents while the mass remains in the uterus. In the carneous moles of small or moderate size active treatment is very much impeded by uncertainty of diag- nosis. If in a case of suspected molar pregnancy the life of the mother should be threatened, the ovum should be detached by a catheter or the uterine sound, without hesitation. The ergot of rye may be given, with a view to the arrest of bleeding and the excitement of uterine contractions ; but in ordinary cases we are obliged to wait, as in abortion, until the ovum presents at the os uteri, or can be reached with the finger, before we attempt to remove it. If the diagnosis of this form of molar pregnancy should become, as we may hope it will, more perfect and certain than it now is, we might separate the ovum by the sound, dilate the os and cervix by sponge tents, or excite the uterus by gal- vanism. In the case of hydatid degeneration the treatment is more positive. It is usual in such cases to give the ergot of rye to induce uterine contraction. If the os uteri is dilatable. we may introduce the hand, and detach the hydatid mass. Dr. Gunning S. Bedford relates the case of a woman in extreme danger from loss of blood, in which he successfully broke down the hydatids with a female catheter. The hydatids are some- times attached very firmly, and I once saw a case in which the uterus had been ruptured by the violence of its contractions in expelling an hydatid mole. In the case of a retained ovum with degeneration of the placenta, the membranes should be ruptured, 232 AFTER-TREATMENT OF MOLAR PREGNANCY. and the expulsion of the diseased ovum brought on, as soon as the mother's health suffers seriously, or the nature of the case becomes unmistakable. The after-treatment of such cases is much the same as after ordinary abortion ; but it must be said that the health is more broken after molar pregnancy than by the results of simple abortion. LECTURE XV. SUPER-FCETATION--EXTRA UTERINE GESTATION--MISSED LABOR. Gentlemen:—The term Super-fcetation is applied to cases in which one gestation having commenced, a second super- venes upon it during the continuation of the first. We must, before approaching this curious subject, separate certain cases which simulate super-fcetation to a certain extent, but are altogether distinct from it. For instance, we referred in the last lecture to cases in which a woman may be delivered of a blighted ovum, and carry on a second foetus to the full term ; or in which a gravid woman may produce a full-grown foetus and a shrivelled ovum at the natural time of parturition. Cases are also met with, in which a patient is delivered of two children at the same time, one of which is considerably more developed than the other. Such cases are termed retarded twins, and it is 'doubtful whether in the case of twins, conceived at the same time, the retarded ovum may be retained in the utero beyond the natural term. The instances here severally referred to, are altogether different in principle from cases of super-foeta- tion, inasmuch as they depend not upon a variation in the time of conception, but upon a difference in the time of development or expulsion, apart from any variation in the time of fecun- dation. There are several conditions under which super-foetation may take place; and as the fecundation in twin cases has an inter- esting relation to this subject, I may mention the chief circum- stances under which twin impregnation occurs. It is probable that in many cases of twin pregnancy the second ovum has been fecundated by a coitus occurring subsequently to the first im- pregnation, and such cases form the most simple instances of super-foetation. But this is not always the case. In rare instan- ces, in twins, the placenta is found to be single, and I would 283 234 OVA IMPREGNATED AT DIFFERENT TIMES. suggest that these are cases in which one ovule has contained two yolks and two germinal vesicles, just as we sometimes see in birds, one egg with a double yolk, producing two individuals. In these cases the twin impregnation must occur at thesametime. More frequently the placentae and membranes are double, but the placentae are placed side by side, and in these cases two separ- ate ovules have probably descended from the same ovary, and have been impregnated either at the same or at different times. In some cases the placentae are attached to opposite sides of the fundus uteri, the inference being that the ova have descended from the two ovaria, but they may have been impregnated by a single coitus or otherwise. In all these cases5 impregnation occurs within a short space of time, and the same preparation of the uterus serves for the twin fecundation. We have the positive proof that twin ova may be impregnated at differ- ent times, in the history of cases in which a white woman is delivered of a white and of a black child, or in which a black woman produces a black and a mulatto, at one birth. In the slave states of America, cases of the latter kind are so common, as to place the matter beyond doubt. Numerous authorities, including Buffon, Dewees, Dunglison, Beck, and others, testify to the facts, that a white woman married to a white man, and admitting a negro to her embraces after intercourse with her hus- band, may give birth to a white and a mulatto child at the same time, or that a negress receiving a white man under simi- lar circumstances, may produce a black and a mulatto infant. In animals which produce many offspring at a birth, it is not at all unfrequent for the young to be the product of intercourse with different males. Dr. Henry, in his excellent essay on Super-fcetation, quotes a case which occurred in the Brazils where the indigenous race is copper-colored, but where there are negroes and whites, in which a Creole woman had three children at a birth, of three different colors, white, brown, and black, with all the features of their respective races. Cases are on record, in which women, the subjects of extra- uterine gestation, have conceived anew, and borne children, while the extra-uterine foetus has remained in the abdomen. M. diet, of Lyons, relates a case which had fallen under his own observation, in which a woman died suddenly, and upon dissection, an extra-uterine foetus of five months was found in SUPER-FG3T A TION. 235 the abdomen, while a foetus of three months occupied the uterus. Cases of abdominal gestation, in which the foetus becomes enclosed in a cyst, and the woman bears other children, are less uncom- mon than the above. Dr. Montgomery details the particulars of an interesting case, in which, two years after an extra-uterine gestation, a woman conceived, and bore three children in suc- cession, while the extra-uterine foetus remained encysted. Many other writers have recorded similar cases. In another variety of super-foetation, the uterus preserves the form met with in the lower animals, being bi-cornual or bi-cor- poreal, and a conception occurs first in one side of the organ, and after a time in the other. It has been observed that in cases of this kind, when one uterus has received an ovum, the other cavity develops a deciduous membrane, a circumstance which has been urged by Dr. Lee and others against the pro- bability of the occurrence of pregnancy in a double organ at two different times. Numerous apparently unexceptionable cases are, however, on record. The museum of the University of Modena contains the uterus of a woman who died of apoplexy in 1847. This woman had borne many children, and on one occasion she became pregnant, and was delivered on the 15th of February, 1817, of a child apparently at the full term. The abdomen diminished on one side only, after her labor, and on the 14th of March, she gave birth to a second mature child. This case was regarded at the time, by Professor Bignardi, as one of super-foetation, with double uterus, and this diagnosis was confirmed on a post-mortem examination, thirty years after- wards, by Dr. Generali. Of the authenticity of this case there can be no doubt. It may be urged that it was only a case of retained and retarded twin; but the probabilities are against such a supposition, and numerous confirmatory cases have been observed by Cassan, Voigtel, and Boivin, in wrhich a considerably longer time occurred between the birth of the two children. It is worthy of remark, that in cases of double or divided uterus, the two portions of the organ show signs of imperfection. Abor- tions are very frequent in such cases, and delivery is difficult from the imperfectation of the uterus. The term double uterus is not strictly correct, because the organ is single, but divided into two cornua. In the early condition of the human embryo, the uterus is always divided, and the so called double uterus 230 DOUBLE UTERUS. is merely the more or less perfect persistence of the embryo type. Occasionally the vagina is also doubled or divided. Fis. 63- Uterus in which the cavity is divided by a septum, the vagina being single. Fig. 64. Bifid condition of the uterus and vagina. But in addition to these forms of super-fcetation, other cases are on record, in which the uterus was proved to possess a sin- gle cavity. In one related by Professor Eisenmann, of Stras- bourg, a woman was delivered of a second child 140 days after the birth of the first, both having been mature. She subsequently bore many other children, and after her death the uterus proved to be single. Unless we discredit this and similar cases OPINIONS OF SUPEE-FGETATION. 237 recorded upon good authority, we must conclude that in addi- tion to the fecundation of two ova at short intervals by two male parents, the occurrence of intra-uterine pregnancy after the com- mencement of extra-uterine gestation, and conception in a second uterus during the course of gestation in a first, pure and simple cases occur, in which, while a single uterus is occupied by one ovum, a second fecundation takes place in the same cavity, some- times within the limits of the third, fourth, or fifth months of gesta- tion. A little more than a year ago, I saw with Mr. Eardley of Westbourne-terrace, the following case:—A young married woman, pregnant for the first time, miscarried at the end of the fifth month, and some hours afterwards a small clot was dis- charged, inclosing a perfectly fresh and healthy ovum of about one month. There were no signs of a double uterus in this case. The patient had menstruated regularly during the time she had been pregnant, and was unwell three weeks before she aborted. She has since been delivered at the full term. Many obstetric writers have combated the occurrence of genuine super-foetation from the difficulty of explaining the occurrence of a second pregnancy while the development of an ovum is going on in utero, so that it may be well to say a few words upon the subject. Dr. Fleetwood Churchill is of opinion that the difficulties in the way of receiving the theory of super-foetation are almost in- surmountable. He considers the deciduous membrane to be a shut sac covering the orifices of the os uteri and Fallopian tubes, and that the plug of tenacious mucus secreted by the cervical canal, as well as the mechanical arrangement of the decidua, apparently render it physically impossible, that the spermatozoa and the ovule can come in contact. Dr. Ramsbotham considers it impossible to suppose that a second impregnation can occur while the uterus is occupied with another ovum, and that the mucous plug of the cervix, and the decidual lining of the uterus, " would prevent the possibility of a fresh conception taking place." Many other obstetricians agree with these excellent authorities. It can, however, be shown that there is no positive physical obstacle to the occurrence of super-fcetation in the mechanical closure of the canal of the cervix uteri, or the uterine apertures of the Fallopian tubes by mucus and decidua. I have, 238 THEORIES OF SUPER-FCETATION. I think, demonstrated, by numerous microscopical examinations, that the mucous plug of pregnancy is in no respect different, except in quality, from the mucus found in the cervix in the unimpregnated state, and through which the active spermatozoa must make their way in ordinary fecundation. I have pointed out that it is, in fact, similar to the secretion formed by the pro- state, as the medium for containing the spermatic particles. As regards the difficulty presented by the decidua at the os uteri internum and the uterine apertures of the Fallopian tubes, William Hunter taught that the decidua was perforated at these points—namely, the upper part of the cervix and the tubal ori- fices, and no one has ever shown to the contrary. I have seen numerous preparations which prove that in early pregnancy the decidua stops short at the upper part of the cervix, leaving an opening into the canal of the cervix, and that the two apertures of the Fallopian tubes are distinctly pervious from the uterus. In the first three months the ovum consists of a bag which is only attached to one portion of the parietes of the uterus, leav- ing the cavity between the decidua vera and reflexa perfectly free. Professor Simpson and Dr. Matthews Duncan have pointed out that in this way the communication between the vagina and the ovary may be free for a certain time after the commencement of gestation. Thus, with the exception of the mucous plug, there is no mechanical impediment between the os uteri and the ovaria, and we have seen that the cervical mucus forms no insuperable obstacle to the ascent of spermato- zoa. Super-foetation, then, cannot be denied from the presumed impossibility of its occurrence. As the bag of the ovum in- creases in size, so as to occupy the whole of the fundus uteri, the mouths of the tubes are pressed upon by the ovum, but the cer- vical, orifice remains open, with the exception of the mucous plug, until the end of gestation, except in placenta preevia. The infrequency of super-foetation probably depends more upon the absence of perfect ovulation during pregnancy, than upon any positive mechanical impediment to the ascent of the spermato- zoa, or the incapacity of the decidua vera to receive a second ovum. The ovum may be impregnated, or become attached and developed, at any period between the upper part of the cervix uteri and the Graafian follicle, or it may fall into the abdominal EXTRA UTERINE PREGNANCY. 239 cavity. Whenever the impregnated ovum does not enter the cavity of the body of the uterus, it is called Extra-Uterine Gestation. The several situations in which this grave error, so to speak, of the generative functions may occur, constitute the different forms of extra-uterine pregnancy. These varieties are, the ovarian, ovario-tubal, tubal, ventral, and interstitial or parietal. In Ovarian gestation, the ovum is impregnated in, and attached to, the Graafian follicle or the external surface of the ovary. In Ovario-tubal gestation, the ovum is attached both to the ovarian and fimbriated extremity of the Fallopian tubes; but it is probable that in the first instance the ovum adheres to one of these organs only, and becomes attached to the other during its development. In tubal gestation, the ovum lodges in the Fallopian tube. In Ventral pregnancy, the .ovum appears to miss the tube, and becomes attached to the peritoneal surface, generally amongst the convolutions of the small intestines. There is one other form of misplaced ovum, which is usually called a variety of extra-uterine gestation, although, strictly speaking, it is not extra-uterine. This, which has been made out by Breschet, is termed' Insterstitial or Parietal gestation. The ovum lodges near the point at which the Fallopian tube enters the uterus, and forms a nidus in the walls of the uterus itself. The ovum in these cases becomes surrounded by a layer of the muscular coat of the uterus, similar to the layer which surrounds the majority of fibrous tumors developed in the walls of the uterus. The ovum, in this form of gestation, is developed in a kind of sub-cavity, formed in the upper part of the uterus, or between the uterine layers at one of the Fallopian angles. We may compare this form of gestation in some respects to pla- centa praevia, in which the attachment of the ovum takes place at the os uteri internum. One or two rare cases have been observed, in which the ovum must have been developed at the very point of junction between the tube and uterus, where the placenta has occupied the uterus, while the rest of the ovum has been contained in a cyst formed by the dilated Fallopian tube. The tubal is the most common form of extra-uterine gestation. The ovum becomes enveloped in the chorion, a decidua is formed, as indeed is the case in all the varieties of extra-uterine pregnancy, and a pouch is developed in the tube, the muscular fibres of the tube being increased to a considerable extent. 240 SYMPTOMS OF EXTRA-UTERINE PREGNANCY. There is, however, a briefer limit to this than to any of the other forms of extra-uterine gestation. It is seldom prolonged beyond the second or third month, at which time, either from thinning, distension, or erosion, the cystic portion of the tube is rent, and the embryo escapes. In very rare cases the tube continues to enlarge, and the embryo remains in its cyst to the end of the natural term of gestation, or even beyond this. If the ovum remains in the tube long enough, an attempt at the formation of the placenta is made, this organ being very thin and vascular, and it is at the part opposite the attachment of the placental tissue that the rupture of the tube usually takes place. Con- temporaneously with the development of the embryo in the tube, a decidual membrane is developed in the uterus in many cases, though this does not occur invariably: The symptoms of tubal pregnancy are in a great measure the symptoms of all the varieties of extra-uterine gestation. The uterus is felt to be somewhat developed, but not to the extent which obtains in intra-uterine gestation. It is high up in the pelvis, so as often to be beyond the reach of the finger, though it is sometimes lower than natural. Menstruation generally ceases, but there is an occasional sanguineous discharge from the uterus in some cases, and there is sometimes an absence of nausea and vomiting. The ordinary changes occur in the breasts. The tumor of pregnancy is felt high up, and chiefly on one side of the abdomen. Altogether the uneasiness experienced in these cases in every variety of extra-utero gestation is greater than in ordinary pregnancies, and often gives the patient the idea of some unnatural condition. When the tube bursts, the patient, generally without any premonition, is seized with agonizing pain, followed by ghastly pallor, fainting, hurried breathing, and fatal collapse. Cases have, however, been met with, in which little pain has attended the rupture of the tube, the symptoms being those of pure collapse. On dissection, the ovum is found in the abdomen, with a rent in the tube, and a large quantity of blood in the peritoneal cavity. At the time of the bursting of the tube, there are indications of uterine excite- ment, and an attempt at detaching the decidua where this structure exists. Death is evidently caused by the loss of blood and by the shock incident to the effusion into the peritoneum. The treatment is unhappily almost nil. Pressure and cold have CURIOUS CASE OF TUBAL GESTATION. 241 been recommended. Restoratives and opiates have been given to allay pain and support the patient, but very rarely with any- thing beyond the most transient good effects. As, with a rare exception or two, all these cases have proved fatal, if the diag- nosis were perfect, it might afford a bare chance of safety, in such a desperate conjuncture, to open the abdomen, and attempt to arrest the flow of blood by deligation of the tube. Fi& 65. Case of tubal gestation. Some years since, Dr. Oldham wrote to ask my opinion upon a curious circumstance which he had observed in a case of tubal gestation. It was, that the corpus luteum was found in the ovary opposite to the side on which the ovum was lodged. Three explanations suggested themselves. The unimpregnated ovule might have been swept by the cilia of the peritoneum from the right ovary to the fimbriated extremity of the left tube. This would be similar to that which occurs in the amphibia, in which the ova always traverse the abdomen to reach the ovi- duct. Or the left tube may have reached over to the right ovary, and have taken up the ovule. This was the opinion to which I believe Dr. Oldham and Mr. Wharton Jones inclined. According to the third explanation, it might be, that the ovule had descended the right tube, entered the uterus, and then ascended through part of the left tube, by an antiperistaltic action, or the ciliated currents, which move from below upwards. My own opinion was in favor of the ovule having entered the uterus by one tube and ascended by the other. Such cases are very interesting in relation to the causes of extra-uterine fceta- tion. Dr. Oldham has now collected three cases of this kind, 16 242 CAUSES OF EXTRA-UTERINE GESTATION. so that they cannot be very uncommon. The following wood- cut is taken from a drawing of one of Dr. Oldham's cases. Fig. 66. Tubal pregnancy, with the corpus luteum on the opposite side. The decidua is in process of detachment from the uterine cavity. As regards the causes of extra-uterine foetation, many hypo- theses have been advanced. It is believed that there is a greater tendency to this accident in the unmarried than in the married, and some curious cases are on record, in which it has happened in women who were the subject of fright or terror at the time of coitus. In these cases emotion would seem to be a cause. In the ovarian and ovario-tubal varieties, it is suggested that inflam- mation of the mucous lining of the follicles, or of the indusium, or the extremities of the tubes, may have caused adhesions of the ovum, and it has been said that these forms are prone to occur in courtezans, in whom ovario-tubal inflammation and adhesion are common. In tubal gestation, there may have been large size of the ovum, feeble peristaltic action of the tube, or inflammation of the tubal mucous membrane. In vental preg- nancy, the cause would seem to be the faulty action of the tube in grasping the ovary. In the interstitial cases the ovum has been supposed to lodge in some fold or depression upon the sur- face of the uterus. In ovarian pregnancy, the early symptoms are the same as in the tubal variety, but the catastrophe does not occur so early, nor does death take place with the same rapidity. The ovum is in some cases attached to the interior of the Graafian vesicle, the placenta combining with the corpus luteum, or it is seated upon RESULTS OF EXTRA-UTERINE PREGNANCIES. 243 the internal surface of the ovary. In the former cases, impreg- nation occurs within the mucous follicle, and the ovule probably never leaves its primary nidus. There is, as in the tubal variety, a thin placenta, and the decidua, chorion, and amnion are formed within the sac. Sometimes death happens as suddenly as in tubal gestation, from the shock and loss of blood attending the rupture of the ovary ; in others, the ovarium increases in size, and the foetus goes on to the full term, when it dies, and may be retained for a considerable period. When this happens, the case follows the course to be presently described, when treating of the termination of ventral pregnancy. In this form of extra- uterine pregnancy, a more or less perfect decidua is formed in the uterus, and there are constant and violent attacks of uterine pain, accompanied by sanguineous discharges. Of the occasional occurrence of ovarian pregnancy there can be no doubt, though it has been questioned, chiefly upon theoretical grounds, by Yelpeau and others. I believe, however, that cases have been ranked in this variety in which no pregnancy of an}r kind existed. Even in the celebrated essay of Dr. Campbell, cases are admitted which are open to doubt. In the case of Louise Adelaide, for instance, on a post-mortem examination, a pouched tumor, occupying the situation of the left ovary, was found, containing hair, teeth, bones, and greasy matter. This may, however, have been a case of ovarian disease without impregnation, in which such structures are sometimes found. The changes in the ovary consequent upon the discharge of an ovule and the formation of a spurious corpus luteum have also, before the function of ovu- lation was understood, been mistaken for commencing ovarian gestation. In the undoubted cases, the entire foetus has been found within the sac, or escaped from a perforation of the ova- rian cyst. The rupture of the ovarian cyst in extra-uterine cases is generally preceded by uneasiness and pain in the tumour, and seems to be effected by an inflammatory process. In the interstitial form of gestation, the development of the foetus usu- ally goes on to the full term. In ovaria-tubal and ventral pregnancy, the ovum draws its nourishment more easily than in other cases, and the structures surrounding it yield, so that the tendency is to go on to the full term of pregnancy. The auscultatory sounds are the same as in natural pregnancy, but the limbs of the foetus are felt 244 DISORGANIZATION OF EXTRA-UTERINE FCETUS. with great distinctness; hardly more so, however, than in some cases of intra-uterine gestation, where the parietes of the uterus are of unusual thinness. If the cyst containing the ovum bursts, the symptoms are similar to those which occur in ovarian or tubal cases, but less severe. The accident generally happens at a later period, when the pressure of the surrounding organs appears to restrain the haemorrhage. When rupiure does not occur, the foetus has a tendency to perish at what would be the time of parturition; uterine contractions with the expulsion of the decidua generally occur; there is a local discharge, and milk is secreted. The death of the foetus is sometimes attended by violent movements and convulsions, of which the mother is sen- sible. These phenomena are probably the result of asphyxia, induced by the unfitness of the placenta to continue its func- tions. In some cases the child has been considerably larger than at the full term, and it has been supposed that it has lived one or even two months beyond the usual time. After the death of the foetus, a process of disorganization slowly commences, the bones separate, and the soft parts become converted into adipo- Fig. 67. . Case of abdominal pregnancy. cerous material. It may become smaller and smaller, the cyst contracting upon it, and remain for a great number of years ART IN EXTRA-UTERINE PREGNANCIES. 245 without causing any considerable inconvenience. More fre- quently, however, it causes great irritation and inflammation, the residual mass attempting to make its way to the surface, or to the rectum and bladder, to be discharged. This process is attended by suppuration, hectic, colliquative sweating and diar- rhoea, great suffering, and deterioration of the general health, which, spreading over a long period, very commonly destroys the life of the patient. Cases, however, occur in which perfect recovery ensues. The treatment of such cases must be considered in relation to the time preceding and subsequent to the death of the foetus. Dr. Campbell records nine cases of ventral pregnancy, in which gastrotomy was performed before the death of the foetus, or shortly afterwards, and all died, probably because of the vascu- lar connection of the placenta with the abdominal viscera Nature appears to be more happy in her mode of proceeding, and when the remains of the foetus point either upon the surface of the abdomen, the vagina, bladder, or rectum, Art may step in and assist the process very efficiently. When the fcetal abscess has burst, the opening may be enlarged to allow of the extrac- tion of the extraneous matter, which consists of a mixture of bones, fatty matter, and the remains of the placenta, which is generally converted into a soft purulent mass. Of thirty cases in which, according to Dr. Campbell, gastrotomy, or the dilata- tion of the breach already effected by suppuration, was practised, twenty-eight recovered. During this process, which may occupy months or even years, the strength of the patient has to be sup- ported, abscesses dealt with, and inflammatory attacks treated as they arise. In the rare cases in which, in ventral pregnancy, the cyst presents low down in the pelvis, and the parts of the child such as the head, hands, or feet, can be felt through the vagina, an incision through the vaginal walls into the cyst is a much more favorable operation than simple gastrotomy. Dr. Campbell states that of nine cases in which incision of the vagina was performed, in three both mothers and infants were saved; in two the mothers only recovered; in one the child alone was preserved ; while in three, both mothers and children perished. The present may be a proper time for mentioning a very curi- ous and extraordinary obstetric and physiological phenomenon. 246 EXTRAORDINARY OBSTETRIC PHENOMENON. far more rare than either super-fcetation or extra-uterine gestation, nd having some relationship with both these abnormal condi- tions. I allude to what has been called Missed tabor, in which the foetus being in utero, parturition from some unascertained cause does not come on at the usual time, but the foetus dies, and remains included in the uterus without causing the immediate death of the mother. Dr. Oldham exhibited the uterus and remains of a foetus, from a most interesting case of this kkid at the first meeting of the Pathological Society in 1846. In this case the child was felt in utero, the fact having been ascertained by Dr. Oldham himself, so that no error can be imagined: but parturition did not occur, nor any attempt at parturition. The child died, and became disorganized, portions of the foetus dis- charging themselves or being removed through the os uteri for the course of three months from the date of the parturient nisus. At the end of this time the woman died ; and on making a post- mortem examination, Dr. Oldham found the remains of the foetus, consisting of a moulded mass of bones and adipocerous matter. This mass had apparently worn through the interior wall of the uterus, apparently as an aneurism makes its way through the tissues with which it is in contact, and was in an imperfect cyst composed of the posterior wall of the uterus and the abdominal parietes. There had been no sign of rupture of the anterior wall of the uterus at any time. The fundus of the bladder was nearly eaten through, so that if the woman had lived, portions of the foetus would probably have escaped from the urethra. Dr. Simpson states that similar cases of missed labor are sometimes met with in cows and other animals, and that, as in the above case, the bones of the foetus became moulded into a compact mass, which may remain a long time in utero. The following wood-cut represents the residual mass removed from the cyst after death, by Dr. Oldham, who has kindly allowed me to have a drawing taken :— From the similarity of symptoms in this case to those cases of abdominal extra-uterine gestation in which the foetus is retained, becomes encysted, and is discharged by the bladder or rectum, it is quite possible that cases of missed labor have been sometimes mistaken for ventral pregnancy. The treatment in cases of missed labor should evidently be to excite the uterus to contraction, if possible, by galvanism or other means, when REMARKABLE PATHOLOGICAL SPECIMEN. 247 the time of labor has passed and the child has been ascertained to be dead, or to combine those means with attempts to break up Fig. 63. Contents of cyst in Dr. Oldham's Case of Missed Labor. the foetus and extract it through the os uteri. When this time has passed by, such cases resemble ventral pregnancy, and re- quire similar treatment. They are, however, perhaps the rar- est obstetric complication that can be met with. [Some years since I saw at the New York Pathological Society, a specimen brought from Virginia, with the history that it was removed from a female negro slave some seventy or eighty years of age, who some forty years previously supposing herself pregnant went into the lying-in department, having all the signs of immediate labor. After several days of severe pains, they sub- sided without anything coming away—she was " good for nothing " for several months or years, but finally got about and resumed her place in her master's kitchen. The tumor in the abdomen, perhaps somewhat diminished, still remained. Some thirty or forty years after, she died of dysentery ; the post-mortem 248 0SSD7ICATI0N OF THE UTERUS AND ITS CONTENTS. showed a bony tumor in the median line, apparently the uterus. When this was sawed in two it was evident that it contained a coiled up foetus, apparently perfect and entirely ossified. A similar case was recorded about the same time as having oc- curred in a different locality.] LECTURE XVI. THE GRAVID UTERUS. Gentlemen :—The unimpregnated, virgin, or nulliparous uterus, is from two inches and a half to two inches and three- quarters in length, its breadth being, from tube to tube, from an inch and a half to an inch and three-quarters. At the end of gestation, the uterus is about thirteen inches long by eight or nine in breadth; its greatest antero-posterior diameter being eight or nine inches. Levret made some calculations, according to which the superficies of tbe virgin uterus may be taken at sixteen inches, while at the time of the coming on of labor, its superficies may be estimated at about three hundred and thirty-nine inches ! The cavity of the unimpregnated virgin is equivalent to about three fourths of a cubic inch ; while, when fully developed, it exceeds four hundred cubic inches! The uterus in the virgin state, weighs about an ounce ; and that of a woman, who has borne children about an ounce and a half. Immediately after labor, the uterus weighs about twenty-four ounces; but this weight is considerably exceeded when it is distended by the foetus, and its vessels are full of blood. These facts show the wonderful manner in which the uterus increases under the stimulus of impregnation—an increase having no phy- siological parallel in any other organ in the human body. This increase is divided between the mucous membrane or decidua, the lymphatics, the veins and arteries, the muscular structure, and the nerves of the organ. The measurement already given represents the general size of the gravid uterus at the full term; but the capacity of the uterus varies much in individual cases, chiefly from the greater or smaller quantity of the liquor amnii, or the occurrence of twins. In sorpe cases, there is only a very small quantity of liquor amnii; and in others, there may be dropsy, and great dis- 249 250 FORM OF THE GRAVID UTERUS. tension of the amnion. The shape of the uterus is ovoid, but its figure somewhat shorter, and the smaller extremity is less pointed than in the egg. The organ is more developed anteriorly than posteriorly ; and it is somewhat flattened behind. It is moderately filled, but not distended, by its contents. Wil- liam Hunter, whose descriptions of the gravid uterus are almost as graphic as his beautiful plates, compares it to a bladder par- tially filled with fluid, in consequence of which it yields to the pressure of the surrounding parts, and is, to some extent, moulded by them in shape. The gravid uterus, when filled with its con- tents, feels much thinner to the touch than it actually is. Its parietes are from one-third to two thirds of an inch in thickness ; but it exceeds this considerably at the site of the placenta. Occasionall}r, in twins, the two lateral valves of the uterus are developed in such a way as to leave a division or cleft between them ; and cases are met with in which, with one foetus, the right or left side of the organ is chiefly developed. It some- times occurs that a particular part of the uterus does not per- fectly take on the growth of normal pregnancy, so that a ridge or contracted portion remains in the interior of the organ. The ligaments of the uterus are considerably altered by the gravid state. As the organ increases in size, it expands between the folds of the broad ligaments, so that in their unfolded state these liga- ments form the peritoneal covering of the sides of the uterus. As a consequence, the broad ligaments and the ovaria, though they ascend during pregnancy, are lower down in their attachment to the uterus, than in the ungravid state. The Fallopian tubes and the ovaria are close to the sides of the uterus, the fimbriated extremities pointing downwards, and the broad ligaments are shortened to the greatest possible extent. The ovarian ligaments lie upon the sides of the uterus, and the round ligaments extend almost perpendicularly downwards from the fundus uteri to the inguinal rings. The development of the decidual mucous membrane has already been described. The lymphatics of the uterus and its appendages, which were first described by Cruikshank, increase from the minute size, and almost invisible, .found in the virgin uterus, to the size of a goose-quill, or even larger, in the princi- pal trunks. The lymphatic vessels pervade every part of the gravid uterus, but are especially abundant underneath the peri- UTERINE ARTERIES, LYMPHATICS AND NERVES. 251 toneal covering. They follow the course of the hypogastric and spermatic bloodvessels, and reach the central lymphatic trunks by entering the glands of the sides of the vagina, and the iliac, sacral, and lumbar plexuses of glands. The lympha- tics are, no doubt, largely concerned in the processes of the nutrition of the uterine tissues during their enormous growth, and in that removal of effete material after labor, which, in the course of five or six weeks, reduces the uterus from a pound and a half in weight, to something less than two ounces. The uterine arteries, both the hypogastrics and spermatics, greatly increase in size, particularly the hypogastrics. This increase is greater at the part of the uterus to which the placenta is attached. The uterine arteries, in ramifying in the structure of the organ, have a tendency to anastomose to such an extent as to form an arterial net-work; and as they plunge deeper into the substance of the uterus, they take a convoluted or spiral course. This spiral arrangement especially occurs before the vessels enter the placenta, the spirals running parallel with the decidua serotina, and immediately beneath it, for the space 01 half an inch or more, before perforating the decidua to pass into the placental mass. The veins, which, in reverse, accom- pany the hypogastric and spermatic arteries, are still more enlarged, and form plexuses especially in the neighborhood of the placenta, and towards the internal surface of the uterus, of a larger extent than are found in any other veins of the body. The uterine veins do not possess valves, and some of the largest are of sufficient size to admit the point of the finger. Altoge- ther, the mass of blood contained by the arteries and veins of the uterus, in the healthy gravid organ, at full term, must be very great, and forms a considerable portion of its entire bulk. The serous or peritoneal covering of the uterus increases in thickness and extent, and but for the increased strength of the serous coat, it is probable that lacerations of the peritoneum would occur during the contractions of the uterus in labor. Formerly, everything was vague respecting the existence and arrangement of the muscular fibres of the uterus. The pos session, even, of muscular fibres by the human uterus was argued because they could be seen in the lower animals, and because from the functions of the uterus, they were necessarily believed to exist in this organ, rather than because they could 252 UTERINE MUSCULAR STRUCTURE. be satisfactorily made out in dissections. In the magnificent plates of William Hunter, the external surface of the uterus presents no definite muscular arrangement. This great anato- mist could find nothing but" irregularity and confusion," except upon the inner surface of the organ, where he observed the fas- ciculi to have in some degree the regular arrangement observed in other muscular structures. His description of the internal layer of muscular fibres is perfect even at the present day. He gives an account of the circular fasciculi surrounding the body of the uterus, and the two concentric circular planes of fibres which surround the orifices of the Fallopian tubes, and gradually blend with the circular fibres of the body of the organ. William Hun- ter saw the analogy between these concentric rings—the orbicu- lares muscles, as he terms them, of the fundus uteri and Fallopian tubes, and the circular muscles found in the two horns of the uterus in animals possessing the uterus bicornua. His words are, " The better to conceive this arrangement of the internal muscular fibres, we may suppose each corner of the fundus uteri, where the tube is inserted, to be stretched or drawn out, so as to make two horns, or a bifid uterus, as in the quadruped ; then, if we understand the inner fibres to be circular in every part of the uterus, we clearly understand how they will be circular in the human uterus upon its body, and likewise circular and concentric at each corner of the fundus." Before this timeRuysch had de- scribed the fundus of the uterus as possessing a single circular muscle only. Sir Charles Bell carried our knowledge of this subject a step further, and described the muscular fibres diverg- ing from the round ligaments to spread over the whole of the organ, and he considered these ligaments as in some respects the tendons of the external fibres of the uterus. His conclusion was, that the circular fibres prevailed towards the fundus, and that the longitudinal fibres were most apparent towards the os and cervix. According to the recent descriptions of Kolliker and other minute anatomists, who have combined the use of the scalpel and the microscope in their investigations, the gravid uterus possesses three layers of muscular fibres, all of them being of a paler color than is found generally in other muscles. These three layers can be made out with tolerable distinctness, but not so clearly as we can make out the circular and longitudinal layers MUSCULAR FIBRES OF THE UTERUS. 253 of the Fallopian tube or intestine. The internal stratum, or the inner layer of William Hunter, is thin, and composed of delicate circular and transverse fibres, the circular fibres being found chiefly in the middle of the body of the uterus, around the Fal- lopian tubes, and at the os uteri, in which latter position they form an imperfect sphincter. The middle layer is thick and strong, consisting of flat bundles of fibres, running in different directions, interlacing with each other, and surrounding the vessels of the uterus. These bundles of fibres are more loosely arranged than those of the internal layer, giving the middle por- tion of the uterine parietes a spongy appearance. This stratum is strongest at the fundus of the uterus, where it seems to consist of several layers. The external layers consist of transverse and longitudinal fibres forming a thin stratum, immediately beneath and intimately connected with the peritoneal covering of the uterus. The longitudinal fibres are arranged chiefly upon the anterior and posterior surfaces of the organ, and extend from the fundus to the lower part of the cervix. The transverse fibres of this layer surround, or nearly so, the organ, and fibres derived from it are continued, not only into the round ligaments but into the broad and ovarian ligaments, so as, in effect, to con- nect the fibrous structure of the uterus with the fibrous stroma of the ovaria. Fie. 69. Internal layer of uterine muscular fibres. Sir Charles Bell pointed out a fact which has been confirmed by subsequent observers—namely, that in all parts of the uterus 254 MUSCULARITY OF THE UTERUS DEMONSTRATED. muscular fibres are found to surround the blood vessels, and that this is especially the case with the open vessels upon the Fie. 70. Middle layer of uterine muscular fibres. Fia. 71. External layer of uterine muscular fibres. surface from which the placenta has been detached. William Hunter had observed that at the site of the placental attachment the inner layer of muscular fibres lost its regularity, and was found to be interlacing amongst the bloodvessels. The bearing of this arrangement upon the arrest of haemorrhage after the placenta has been detached is obvious. Sir Charles Bell found that when the muscular fibres were contracted the mouths of the vessels were closed, and vice versa. FIBRK CELLS OF THE UTERUS. 255 As regards the intimate structure of these muscular laj^ers, upon which the great increase in the mass of the uterus depends, much has been made out by recent inquirers, especially by Virchow, Franz Kilian, Ileschl, and by Mr. Rainey in this country. The mode of Involution and Devolution of the uterus during pregnancy and after parturition is now tolerably well understood. When describing the unimpregnated uterus, we have seen that the chief bulk of the organ is made up of fusiform embryonic cells, possessing a central nucleus. The embryo fibre cells are described by Kolliker as about TJj-o °f an inch in diameter, their length being somewhat greater than their diameter. As soon as fecundation and the deposition of the ovum has occurred, these fibre cells begin to elongate by growth at each extremity, the nucleus remaining in the middle portion of the filament. The nucleus itself elongates, but the great increase in length is in the portion of the cell surrounding the nucleus. At the time of parturition, the fibre cells have so increased, they measure in length from seven to eleven times greater than in the embryonic state. Their width is also increased from two to five times. There is not only an increase in the fibre cells already existing in the uterus at the time of conception, but new generations of fibre cells are produced during the course of gestation. This new development of cells takes place chiefly in the internal and middle muscular layers though it also occurs in the outer layer. The new formation is especially active during the first half of pregnancy. After the sixth month it is believed to cease, and from this time the embryonic cells are all developed, so that at the time of partu- rition nothing but the colossal fibre cells are met with. It is those fibre cells which collectively give the uterus its enormous contractile power at the time of parturition. The ligaments of the uterus increase in size chiefly from the development of the muscular fibres which they contain. This is particularly the case with the round ligaments, and Kolliker'supposes that the enlargement may depend upon the growth of the fibres derived from the uterus, and also upon the increase of the bundles from the internal oblique, which contribute to form the ligamenta rotunda. (Fig. 72.) After the occurrence of labor, these gigantic fibre cells are no longer needed, and the uterus has to return in a comparatively short space of time from a weight of twenty-four ounces to one 256 FATTY DEGENERATION OF THE UTERUS. ounce and a half. The necessary involution of the uterus is effected chiefly by the atrophy and fatty degeneration of the Fig. 72. 1 and 2, Embryonic nucleated fibre cells of the unimpregnated uterus ; 8, 4, 5, Muscular fibre cells of the gravid uterus in different stages of development. colossal muscular fibres, and the absorption and removal of the fatty matter of the kidneys, the mammary glands, and the inter- nal surface of the uterus itself. The whole uterus becomes soft: it is difficult to insulate individual fibre cells, from their exces- sive friability, and they are found to be studded with oily parti- cles in their interior. The disintegrated muscular fibre of the uterus, taken into the system by absorption, probably contri- butes to the formation of the caseous matter of the milk first secreted, and fatty elements are found in the urine at this time, and abundantly in the lochial discharge. A brief, but very- excellent account of the post-partum changes occurring in the uterus has been given by Dr. West, in the thirty-fourth volume of the " Medico-Chirurgical Transactions." During the involu- NERVES OF THE UTERUS. 257 Fig. 73. tion of the uterus after labor, chiefly as we have seen, by the fatty degeneration of the muscular fibres, a new series of nucle- ated fibre cells, having the shape and size of the fibre cells of the virgin, or nulliparous uterus, is formed. Kolliker states that three weeks ofter parturition the embryonic fibre cells again appear, though a longer time than this expires before the com- plete fatty disintegration and absorption or discharge of the developed fibres is accomplished. Probably two or three months have elapsed before the involution of the uterus after delivery is completed ; frequently the involution, as pointed out by Dr. Simpson, is not complete, when menorrhagia is the result. In other cases the involution is excessive, the uterus becomes smaller than before the occurrence of impregnation, leads to amenorrhcea, and subsequent infertility. Thus, as observed by Franz Kilian and Mr. Rainey, the highly develop- ed muscular structure is removed, and a more lowly organized structure formed in its place for each labor, so that the gravid uterus in each successive pregnancy is to a great extent, a new organ. Fig 73. The uterus receives its supply of nerves from the hypogastric, sacral, and spermatic nerves. Below the bifurcation of the aorta, we have the aortic plexus divi- ding into the two hypogastric nerves. The hypogas- tric nerve on each side forms, in its descent to the cer- vix uteri, the hypogastric plexus. The hypogastric plexus, when it reaches the cervix, terminates accord- ing to the dissections of Dr. Lee, in the hypogastric ganglion. Into the outer and lower portion of the hypogastric ganglion branches enter from the third, and sometimes from the second and fourth, sacral nerves. From this ganglion nervous fibres are distri- buted to the muscular structure and the internal sur- face of the os, cervix, and the body of the uterus. Dr. Lee describes sub-peritoneal ganglia and plexuses upon the external surface of the uterus, which maintain connection with the hypogastric ganglion below, and the spermatic ganglion and plexus above. The nerves of the virgin uterus are arranged in a serpentine form, and are always accompanied by a branch of an artery and vein. n Muscular fibre cells a fortnight after deli- very,^ a state of fatty degenera- tion. 558 dr. lee's dissections of the uterine nerves. We now approach the much-vexed question of whether the nerves of the uterus increase during pregnancy or not, than which nothing has more agitated or perplexed the anatomical and obstetric world in modern times. William Hunter, arguing from analogy, suspected that the uterine nerves enlarged in the same proportion as the bloodvessels. John Hunter thought the gravid uterus independent of nervous agency, and capable of motion " within itself," and he denied that the nerves were in the slightest degree increased during pregnancy. Tiedemann was the first to publish figures of the nerves of the gravid uterus, copied from actual dissections; but his two plates, taken from a woman who died six days after delivery, represent a very sparing supply of nerves. Since this time, it has been gener- ally assumed that the nerves of the uterus are thicker at the time of parturition, than in the unimpregnated state, though some anatomists, as Lobstein, Osiander, and Longet, have either denied the existence of uterine nerves, or have limited this organ to a very scanty supply, both in the unimpregnated and gravid states. Dr. Lee, many years ago, threw himself into the investigation of this subject, and he has pursued it ever since with characteristic ardor. He has made numerous dissections, which in his own opinion, and in that of a host of authorities who have examined his preparations, prove to demonstration that the nerves of the uterus increase to a very great extent during pregnancy. All analogy and reasoning are in favor of the truth and fidelity of Dr. Lee's dissections ; and the most recent investigations, by those aloof from all personal feeling, are chiefly in his favor. Remak states, as the result of his investigations, that the nerves enlarge during gestation. Kilian has made numerous researches in the lower animals, which prove that the nervous fibres, in a medullated condition, can, during pregnancy, be traced further into the substance of the uterus than at other times ; while, in the unimpregnated uterus, the nervous fibres are found, even upon the surface of the uterus, in an embryonic, non-medullated state. Kolliker can see no impossibility in the multiplication of ganglion cells and fibres, and in the addition of newly-formed nerve fibres, as branches to other nervous fibres, or that the nerves, by a multi- plication of their ultimate divisions, may ramify over larger spaces during pregnancy than at other times. That the pre- DR. 8N0W BECK'S DISSECTION OF THE UTERINE NERVES. 259 existing nervous fibres increase in width and length, and may be traced further into the interior of the uterus in the gravid organ than at other times, Kolliker entertains no doubt. Dr. Lee believes that very shortly after labor the uterine nerves diminish in size, and return to the condition which obtains in the unimpregnated state. Dr. Snow Beck has executed some dissections of the gravid uterus, which appear to contradict those of Dr. Lee. Dr. Snow Beck believes that the nerves of the uterus are not by any means so large or so numerous as they appear in Dr. Lee's dis- sections. He considers that the nervous arrangement at the neck of the uterus should be called the pelvic plexus, instead of the hypogastric ganglion; and that the sacral nerves do not enter into that portion of the cervical plexus which supplies the uterus, but that they are distributed to the vagina and other parts. Dr. Snow Beck further believes that there is no increase in the size of the nerves during pregnancy, but simply that the nerves which, in the virgin uterus, have a sinuous arrangement, become straitened during gestation. There are, it must be said, certain anatomists, having great authority, who hold with Dr. Snow Beck that the nervous supply of the uterus is very restricted, having little relation, as regards size, with the import- ance of the functions it is called upon to perform. It should be said, that Dr. Lee and Dr. Snow Beck have executed their dis- sections upon a different principle, which may go somewhat towards accounting for the different results at which they have arrived. Dr. Snow Beck has, by very minute dissections, cleared the nerves of the neurilemma; while in most of his dis- dissections, Dr. Lee has preserved the neurilemma, as a consti- tuent part of the nerves. But for this difference, the results of the two dissections could scarcely have been so antagonistic as they now are. With every anxiety to form a correct opinion, I think it must be said, that during the last few years, the new evidence which has been brought to bear upon this important subject has been very greatly in Dr. Lee's favor. According to the recent investigations of M. Robin, P. Hes- chel and others, it is the neurilemma of the nerves which chiefly enlarges during pregnancy. Dr. Lee has contended for this, and it is a point which bears directly upon the dissection of the nerves of the gravid uterus by Dr. Snow Beck, in which the 260 DR. BECK VS. DR. LEE. neurilemma was as far as possible removed. [It is now con- sidered that Dr. Beck has satisfactorily refuted the opinions set forth by Dr. Lee.] Fig. 75. The left hypogastric and sacral nerves entering the hypogastric ganglion, with the blood- vessels, nerves, and ganglia of the Virgin Uterus, a portion of the neurilemma being removed, and the size of the ganglia and nerves being thereby reduced below the natural size.—{From Dr. Lee.) 3710 5 LECTURE XVII. THE NERVI-MOTOR FUNCTIONS OF THE UTERUS. Gentlemen :—Uterine muscular and nerve fibre have been considered in the last Lecture, and we come now to the study of the motor functions performed by the gravid uterus. The developed organ is as strictly a muscle as the heart or dia- phragm, and it is the chief agent by which the expulsion of the foetus is effected. It is of immense importance that the nature- of uterine muscular action should be understood, since we are obliged to take it into account in all cases of natural labor, and still more so in cases of preternatural parturition. One class of accidents during labor, of which rupture of the uterus is in the type, arises from excessive uterine action; while another class of scarcely less importance, of which haemorrhage may be regarded as an instance, depends upon deficient uterine action. The older writers thought much of this subject, though the data upon which they reasoned were slender and imperfect. It is, however, remarkable, that considering the interest of the sub- ject, it has not been satisfactorily discussed in any modern work upon obstetrics. The little that we know upon the subject has been almost entirely confined to works on physiology. This has arisen, in great part, from the idea that the uterus was so unlike the general muscular system, that it could not be reduced to physiological rule. But the muscular structure of the uterus, and its dependence upon the nervous system, having been made out in recent times, it becomes necessary to study accurately the nervi-motor endowments of the gravid organ, which is certainly the largest, and as regards the perpetuation of the race, the most important muscle in the human economy. The uterus is in relation with the Cerebral, Spinal, and Gan- glionic divisions of the nervous system, and possesses properties derived from each of these sources of motor power. 2C1 262 MIND, AS IT AFFECTS UTERINE ACTION. In the first place, let us consider the relation of the Cere- bral system to uterine motor action. The uterus is withdrawn from the direct influence of Volition. The will has no direct power either to contract or to dilate this organ. Labor may take place when cerebral paralysis exists, the will being entirely in abeyance, but the uterine move- ments dependent on reflex action and peristaltic action remain- ing perfect. But though not exerting any direct influence, vo- lition may affect the uterus indirectly. In certain cases of uterine inertia, when the contractions of the uterus have entirely ceased, voluntary efforts are sometimes sufficient to reproduce uterine contractions. Efforts at expiration, with the glottis closed, cause the abdominal muscles to compress the uterus mechanically, and this compression stimulates the uterus in the same way as manual irritation of the organ. What is called in other organs consensual action, may also probably be excited in the uterus, to some degree, by volition. Violent voluntary action quickens the action of the heart, and the voluntary con- traction of the internal rectus muscle contracts the iris, though both the heart and the iris are removed from the direct action ot volition. In a similar manner, the uterus during parturition, is probably affected during the intense efforts at expiration and bearing-down, which accompany the pains of labor. A very powerful influence may be exerted upon the uterus by Emotion. A fright, or any violent mental disturbance may bring on labor prematurely, or produce abortion. During labor, any sudden emotion of the mind may increase or arrest uterine action. The different effects of hope or despair on the com- mencement, progress, and termination of labor have frequently been remarked. Emotion often plays the part of Tantalus to the accoucheur. His entrance into the lying-in room may arrest the pains of labor for a time, through the influence of emotion, but if he should leave the house, they as often return with increased vigor, and terminate the labor abruptly in his absence. After delivery, the maternal emotion exerted by the sight of the infant causes the uterus to contract in a remarkable manner. Emotional, like voluntary action, is psychical in its nature, and originates in the cerebrum; but it acts upon the uterus and other parts through the spinal marrow, this great organ of phy- sical motion. This is evident fr,om the fact that emotional move- UTERrNE ACTION BOTH REFLEX AND PERISTALTIC. 263 ments may occur in parts which are entirely paralyzed to cere- bral voluntary motion. Let us now refer to the forms of uterine action depending upon the Spinal Marrow, a subject which did not admit of com- prehension, before the brilliant discovery of the spinal system by Dr. Marshall Hall. The Reflex, Spinal, or Diastaltic action of the uterus is excited in various modes; and it is upon this form of contraction, aided by peristaltic action, and the extra-uterine reflex actions excited during the process, that natural parturition essentially depends. Contraction of the uterus, of a reflex or diastaltic kind, may be excited by irritation of the mammae, as in the act of suckling the infant; by the impression of cold upon the vulva or abdo- minal surface; by irritation of the rectum, as by a stimulating enema; by gastric irritation, as in drinking a gulp of cold water, or swallowing a piece of ice; by ovarian excitement, as in occurrence of abortion from the menstrual nidus ; by irritation of the vagina or pressure on the perinaeum, and by irritation of the os and cervix uteri. These facts supply the proof that the uterus is endowed with reflex action, and that the motor nerves of the uterus are in relation with the mammary, pubic, rectal, pneumogastric, ovarian and vaginal nerves, and the nerves of the os and cervix uteri, as incident excitor nerves. There can be no doubt that in an organ thus subject to reflex action, its own nerves are exciters, and that in all contractions of the uterus, excited by irritation of the internal surface of the uterus, or of the os and cervix during the passage of the foetus, the uterine actions are both reflex and peristaltic. That the internal surface of the uterus possesses incident spinal nerves is proved by the occurrence of vomiting, etc., from uterine irrita- tion. There is, indeed, no instance of a mucous surface wanting the power of exciting reflex action in other parts of the body. It is a question if any pure spinal fibres reach or proceed from the uterus, unmixed with fibres from the ganglionic. This admixture produces a curious effect upon the reflex contractions of the organ. If we irritate the conjunctiva with a feather, the orbicularis muscle contracts instantly. If we tickle the fauces, efforts at vomiting are immediately produced. But in the case of the uterus, contraction does not follow upon the irritation in so sudden a manner. I have sometimes, in cases of alarming 264 CHARACTER OF THE UTERINE ACTION. haemorrhage, had my hand in the uterus for a considerable time, and have carefully watched the influence of reflex stimuli upon the uterus. If, while the uterus remains flaccid, cold water is sprinkled upon the face, the uterus does not contract at once, but after an interval of half a minute to a minute, or even lon- ger, the organ slowly begins to contract, reaches its acme by degrees, and as slowly relaxes. The same thing happens if, while the hand remains in utero, cold or iced water be injected into the cavity of the organ. As a motor organ, the uterus stands alone in many respects. Unlike the rectum and bladder, it is not directly influenced by volition ; and unlike the heart, it is extremely prone to reflex action. It more nearly resembles the oesophagus, which is unin- fluenced by the will, but endowed with the reflex motion and peristaltic action. It differs, however, from the oesophagus in the number of excitor surfaces with which the spinal system places it in relation. There is no other organ, not even the stomach, which can be excited by so many distinct organs, or which acts as such an extensive excitor of motor action in other parts, both in the impregnated and unimpregnated states, as the uterus. Besides the reflex action of the spinal marrow, and its system of excitor and motor nerves, there is the Direct action of the spinal centre to be considered, though this form of spinal action does not play the important part assigned to it by Serres, Bra- 'chet, and Segalas. In what is termed Direct or Centric spinal action, the spinal centre with its motor nerves are concerned, to the exclusion of the incident or excitor nerves. Various instances of Centric spinal action may be given. Thus, ergo- tine passing into the blood, affects the spinal centre, and its effects reach the uterus by its motor nerves. Other oxytoxic agents, such strychnia, carbonic acid, savin, aloes, alcohol, the biborate of soda, and probably ipecacuanha, act in a similar manner. The state of the circulation affects the spinal centre in a very distinct manner. It is well known that there is one form of puerperal convulsion depending upon haemorrhage, where the heart and great vessels have been nearly emptied of blood, and another caused by fullness of circulation. The con- vulsion probably depends greatly upon the influence of defi- ciency or excess of blood in the vessels of the nervous centres. Want or excess of blood, or materies morbi in the circulation, act, UTERINE ACTION AFTER DEATH. 265 then as direct stimuli to the spinal centre, and in this way the state of the circulation affects the uterus during labor. The uterus acts with increased force when the circulation is either plethoric or anaemic; though in the latter case, exhaustion of its nervous energy quickly ensues. We now come to the consideration of Peristaltic action, Ganglionic motor action. When any part of a muscular organ supplied in whole or in part by the ganglionic system of nerves is irritated, the contrac- tion which ensues generally spreads in a vermicular manner to a distance from the point of irritation, and continues for some time after the exciting cause is removed. This is called Peris- taltic motion or action. The uterus is eminently endowed with this peristaltic form of contraction. When one point of the uterus is stimulated, through the abdominal parietes, or by the introduction of the hand into the uterus, the contraction excited extends to the whole organ. Harvey described this peristaltic action of the uterus in the doe. William Hunter saw it in the cat and rabbit. Muller observed it in the uterus of the rat and the oviduct of the turtle, and I have seen it in the uterus of the guinea-pig and other animals. The heart, oesophagus, and intes- tine may be excited to contraction after death; and I have seen the uterus and vagina of the rabbit contract rhythmically, when irritated, for several hours after the cessation of respi- ration. Many cases are on record in which women have died undelivered, but the child has been expelled spontaneously after death. In one case a woman dying during labor was placed in a coffin, and the foetus was found the next day perfectly expelled. This post-mortem parturition must generally depend upon peris- taltic action, commencing after the occurrence of somatic death, or upon the rigor mortis affecting the uterus. It is well known that the rigor mortis affects the other involuntary muscles, and especially the heart, which is contracted by this influence to such an extent as to empty the ventricles, and even to stimulate concentric hypertrophy. Cases are related in which the foetus has apparently been expelled some days after the death of the mother by gaseous distension of the abdomen; but these are different from cases occurring shortly after death, and before decomposition has set in. In the living subject, the peristaltic action of the uterus is the basis of the other uterine actions. In 266 EXPERIMENTS ON TOE SOURCE OF UTERINE ACTION. natural labor it is combined with reflex uterine action, and with various forms of extra-uterine action ; but, under certain cir- cumstances, it seems able to effect the expulsion of the child without other aid. In paraplegia from disease of the lower part of the spinal marrow, or in animals reduced to the same state by experiment, the peristaltic action is the chief power remain- ing to the uterus. In such cases, delivery has been effected in an imperfect manner by the peristaltic action of the uterus or the application of galvanism to the organ. It is not, however, known how much of the spinal marrow must be destroyed before the reflex or diastaltic actions of the uterus cease. Certain experiments have been performed by various physio- logists, with a view to determine the nature of uterine action. M. Serres found that on dividing the spinal cord in gravid ani- mals before the time of parturition, death ensued at variable intervals, but abortion did not necessarily occur. He then divided the cord in animals after the commencement of parturi- tion, and the process was arrested. ' In other experiments, he excited abortion in animals by irritating the spinal marrow in the lumbar region. M. Brachet divided the cord in guinea-pigs between the twelfth and thirteenth dorsal vertebrae, after the commencement of labor, and everything but feeble contractions of the uterus were arrested, the animals dying in a few days undelivered. M. Segalas made a section of the cord high up, without influencing the uterus ; but the organ was paralysed when the division was practised low down. Cases are detailed by MM. Brachet and Ollivier, as occurring in the human subject, in which, in paralysis depending upon disease high up in the spinal marrow, uterine action was not interfered with, but was diminished or suspended altogether in cases of paraplegia, the result of injury or disease, low down in the cord. Dr. Simpson has, I have understood, performed some experiments upon pigs which go to negative the experiments of MM. Serres, Bra- chet, and Segalas. In Dr. Simpson's experiments, which have not been published, I believe parturition occurred notwithstand- ing the destruction of the lower portion of the spinal marrow. If Dr. Simpson's results are as I have stated, they will not prove the independence of the uterus of reflex action, since from the connections of the greater and lesser splanchnic nerves and the thoracic, abdominal, and pelvic plexuses and ganglia, it is quite CHARACTER OF A UTERINE CONTRACTION. 267 possible that the uterus may receive spinal fibres from the upper part of the spinal marrow. The direction taken by the peristaltic action is of considerable importance. Professor Miiller, Michaelis, and Wigand teach that uterine contraction commences at the cervix, and travels towards the fundus ; returning thence towards the os uteri. This is thought by Michaelis to prevent prolapsus of the umbilical cord and the descent of the arms of the foetus before the head ; the cord and the arm, when lying low in the uterus being swept upwards beyond the risk of danger, at the commencement of every pain. Wigand considers the direction of the contraction to be proved by the phenomena attending a labor-pain. At first the os uteri grows tense, the head or presenting part recedes from the touch, and the bladder of membranes protrudes ; after this the fundus uteri becomes hard, and the presenting part of the child begins to advance. I believe this view of Wigand, which has been particularly insisted upon by Dr. Rigby, to be a very accurate description of the direction in which the uterus contracts during a labor-pain. If, as is most probable, the peristaltic action of the uterus does take this course, it is not singular, for, according to the observa- tions of Magendie, the contents of the stomach are, during diges- tion, passed through the pylorus, by a peristaltic movement, which begins at the pylorus, proceeds to the cardia, and then sweeps back again from left to right. Miiller also describes the contraction of the heart of the frog as commencing in the venous trunks; then descending, in succession, to the auricles and ven- tricles ; and then affecting the bulbous aortae. The peristaltic action commences at the auricle, travels to the apex, and then returns towards the base of the ventricle. There seem good rea- sons for the commencement of the peristaltic action at the cervix in the human subject, in the necessity which exists for some pro- vision against prolapsus of the cord, and arm-presentations ; and still more, from the great probability that, if contractions com- menced at the fundus uteri, inversion of the organ would- be a frequent accident. In addition to the divers forms of uterine contraction, the Dilatation of the os and cervix uteri remains to be con- sidered. The dilatation of the os uteri is, in part, mechanical or passive, depending on the contraction of the longitudinal 2GS DILATATION OF THE OS UTERI. fibres of the uterus, which tend to pull the os uteri open, and on the fluid pressure of the liquor amnii on the advancing head of the foetus. But, in addition to the mechanical distension, the os uteri is in part opened by an active mechanical dilatation. The presence of a power for dilatation in the os uteri is not more remarkable that its power of contraction after the comple- tion of labor. We have seen that the os uteri contains numer- ous fibres arranged in a circular form. But the muscular fibres of the uterus, though of considerable length, do not at any point surround the organ, either in the body or at the os or cervix. This circular arrangement of the fibres, without the existence of single fibres sufficiently long to surround the os uteri, accounts for its power of contraction and dilatation. Before the com- mencement of labor in primipara, the os uteri is quite closed; while in parturition it is dilated to such an extent as to permit the passage of the child's head—a mass whose shortest diameter is three inches and a half, making the line of the circle necessary for its passage, nearly eleven inches. This is a dil- atation far exceeding that required in the action of the recog- nized sphincters, and we cannot but believe that if complete circular fibres existed at the os uteri, laceration would be inevi- table. Some of the physiological proofs of the possession of dilatile and contractile powers by the os and cervix uteri may be enu- merated, and these proofs are not less convincing than the most certain anatomical evidence. In the first place, if the fibres of the cervix contracted with the same force as the fibres of the rest of the uterus, this organ could scarcely be emptied of its contents. Doubtless the contractions of the body and fundus uteri are strong, their bearing upon the cervix powerful, and the amniotic bag admirably adapted for mechanical distension ; but it must be remembered that the short fibres of the cervix act at a great mechanical advantage, as compared with the fibres in any other district of the uterus. Let any one who supposes the body and the fundus may forcibly overcome a contracted state of the os and cervix, consider that the united power of all the respiratory muscles is insufficient to force the small muscles which close the glottis. The nature of the haemorrhage in placenta praevia, as compared with haemorrhage from the fundus, affords the strongest argument in favor of a positive dilatation of the os OS UTERI, HOW DILATED. 269 uteri. In haemorrhage from the fundus, the loss of blood is arrested during a pain, because the fundus is in a state of con- traction ; in haemorrhage from the os and cervix, the flow is increased at each return of the pains, because the cervix is in a state of dilatation. If the dilatation were merely a mechanical distention, the pressure which dilated the os uteri would arrest the haemorrhage at the same time. Owing to the mixed mechanical and muscular dilatation of the os uteri, it generally opens slowly; cases, however, occur, in which, after long-continued rigidity, it dilates so suddenly, that even from this fact alone it is difficult to consider it a mere mechanical distension, the resiliency of the part affecting its sub- sequent contraction. But the strongest physiological proof of the existence of muscular power in the os and cervix uteri is the forcible contraction which sometimes occurs after full dila- tation—as, for instance, in cases of encysted placenta, in which the fingers can only be introduced with the greatest difficulty ; and again, in inversio uteri, where the speedy and powerful con- traction of the cervix is one of the elements of the accidents most opposed to the re-position of the organs. LECTURE XVHI. THE F03TUS IN UTERO. Gentlemen :—It was an antiquated and fanciful notion, that the foetus sat upright in utero, rubbing its head against the maternal stomach, so as to cause heartburn ; and it was supposed that the larger quantity of hair in boys caused a greater amount of heartburn than occurred with female children. Even as late as the time of Sir Fielding Oulde, in the middle of the last cen- tury, it was believed that the head of the foetus was uppermost until the time of the coming on of labor. Although modern Fig> 76. Attitude of the mature fetus in utero. researches have shown, that in the latter part of pregnancy, in the great majority of cases, the head of the foetus is found over the 270 OVOID SHAPE OF THE UTERUS. 271 os uteri, obstetricians are not yet agreed as to the precise causes which produce this result. The mature foetus in utero and the gravid uterus have commonly, since the time of William Hunter, been described as two ovals, the one accurately adapted to the other. Strictly speaking, the foetus and uterus are pyriform rather than oval; but the foetus and uterus are each composed of two oval, rather than circular, figures. In the foetus, one oval is formed by the head, and the other by the body and limbs of the child. These parts correspond with the two ovals, into Fib. 17. Outline of the ovoid uterus. which the developed cervix and developed body of the uterus may be divided. The lower oval of the foetus—that is to say, the head—is little compressible, while the upper and larger oval is greatly so, during the progress of labor; and thus, having in view their different degrees of compressibility, the cranial oval may be considered as the larger and more permanent of the two. Bearing these circumstances in mind, it will, however, be conve- nient to speak in general terms of the foetus and uterus as ovoid. The lower end of the foetal ovoid is formed by the vertex, the upper end by the nates. The outline of one side of the oval is formed by the occiput, the back of the neck, and the incurvated spine; the other, by the forehead and the mass of contracted limbs gathered up together. The chin is close to the sternum, 272 OVOID SHAPE OF THE F03TU8. the arms are crossed upon the breast, and the thighs are bent upon the trunk, so that the knees approach the elbows in front Fia. 78. • Ovoid form of foetus at full term. of the abdomen; the legs are bent upon the thighs and decus- sate each other, the feet approaching the nates. The position of the extremities, particularly of the upper limbs, varies, how- ever in different cases. fig, 79. POSITION OF THE F03TUS IN UTERO. 273 We possess satisfactory proof that the child assumes the posi- tion with the head presenting, in the latter months of gestation, and that dead children do not assume this position with the same frequency as the living. The statistics of Dr. Collins extend to upwards of 16,000 children. In the living children, which ex- ceeded 15,000, only 1 in 57 presented preternaturally, or other- wise than the head ; while of upwards of 500 children born in a putrid state, 1 in 5 presented preternaturally. Dubois found that in births occurring before the sixth month, only 52 per cent. were head presentations; of those born during the seventh month, the head presentations increased to 68 per cent.; during the eight and ninth months, to 76, and at the full term, to 96 per cent. From an extended table made by Dr. Simpson, from the report of La Chapelle, Boivin, Clarke, and Collins, amounting in the aggregate, to upwards of 48,000 cases, the proportion of cephalic presentations amounted to 96 per cent. Dubois obtained another important result similar to that deducible from the tables of Dr. Collins, by comparing the comparative frequency of cephalic presentations in dead and living children. Of children born liv- ing in the seventh month, the head presentations were in the pro- portion of 82 per cent.; but in dead children born during the seventh month, the proportions were reversed, no less than 55 per cent, being preternatural presentations. The chief causes to which the general presentation of the head in living children at the full term has been referred in modern times are Physical Gravitation, Instinctive and Voluntary move- ments of the foetus, and Reflex foetal movements. No opinion respecting the cause of cephalic presentation has prevailed so extensively as that which referred it to Physical Gravitation. It was supposed that the weight of the head, as compared with the rest of the body, contributed to its subsidence in the waters of the amnion, and it was further believed that this tendency was increased by the insertion of the umbilical cord in such a manner as to leave the upper part of the body heavier than the lower, when suspended from the umbilicus. Dubois found, however, that in experiments in which the foetus was sus- pended in a bath, or in a receptacle having the shape of the uterus, it was not the head, but the scapula or the back which first touched the bottom. This was the result in dead new-born foetuses of various ages between the fourth and ninth month. 18 274 CAUSE OF THE POSITION OF THE FOETUS. Any argument drawn from the supposed suspension of the foetus by the cord is evidently worthless. The length of the cord is so great as to render any suspension of the foetus by the cord in the liquor amnii impossible. Moreover, if the cord were short, it is generally implanted not into the fundus, but into the side of the uterus. It is also found that twisting of the cord round the limbs or neck of the foetus exerts no influence upon the presen- tation, which it should do, if suspension by the cord contributed to the descent of the head. The drift of all fact and argument seemed, then, against gravitation as a cause of cephalic presenta- tion in the foetus. Recently, however, Dr. Matthews Duncan has advanced some interesting facts which claim for gravitation a considerable share in determining the intra-uterine foetal attitudes. Dr. Duncan has pointed out that when the mother is in the upright position the foetus lies in utero, at an angle of thirty degrees with the horizon. This plane of support is formed by the glabrous internal surface of the anterior wall of the uterus, and the abdominal parietes. When the woman is lying on her back, the child is still upon an inclined plane, having nearly a similar angle. The plane is now, however, formed by the vertebral column, the abdominal viscera, and the posterior wall of the uterus. It is only when the woman lies upon either side, that the foetus assumes the horizontal posi- tion. The greater part of the twenty-four hours is passed with the foetus lying upon one of these planes. In the upright posi- tion, and when the woman is in constant motion, the influence of gravitation, as far as it extends, must have greater scope than during the horizontal position. The mechanical tendency of the foetus is to slide down the plane, but this is resisted to some ex- tent by the plane itself, and by the pelvis. This resistance, thus divided, forms the support of the foetus and of the gravid uterus. The foetus must be considered not as subsiding simply in water, but as sliding down a plane in an ovoid cavity surrounded by fluid. Under such circumstances, it is contended that the foetus must have a tendency to obey the laws of gravity, and, with the restrictions mentioned, to slide down the plane. The objection to this is, that in women who preserve the horizontal position dur- ing the whole of the latter part of pregnancy, the head presents; but cases of this kind are not sufficiently numerous to found a positive argument upon them. THEORY OF FG3TAL GRAVITATION. 275 One argument used against foetal gravitation is, that the head does not present with the same frequency in cases of hydro- cephalus, as in the case of the healthy foetus. Dr. Simpson dwells upon the increased weight of the bones of the head and its con- tents, and shows, by a collection of such cases by Dr. Keith, as many as 1 in 6 present preternaturally—the proportion in ordi- nary cases, it will be remembered, being only 1 in 57. Dr. Duncan points out that it is the relative weight of the head in hydrocephalus, as compared with the density of the liquor amnii, which must be considered. Though heavier in air, it is probably more buoyant in water, than the normal foetal head. To this may be added that the size of the foetal hydrocephalic head is frequently such as to render its descent into the pelvis, and its presentation at the os uteri, impossible. But the strongest evidence against the theory of gravitation was that derived from the greater frequency of preternatural presentations in dead, as compared with living children. It was argued that the dead child ought to obey the laws of gravity as readily and accurately as the living. But it seem to have been forgotten that death may possibly alter the specific gravity of the foetus. Dr. Duncan found, as the result of fourteen expe- riments, that when the healthy still-born foetus is placed in fluid of its own specific gravity, it floats obliquely with the head low- est, in a position corresponding to that which it maintains in utero. He further observed, that in cases where the child has died in utero, before the time of birth, changes occur which make it float with its head highest, in a fluid of its own specific gravity. This circumstance, he suggests, may have some influ- ence in determining the frequency of malpresentations in the case of dead children; but he admits that a more extended course of experiments will be necessary before full confidence can be claimed for such results. The ingenious observations and experi- ments of Dr. Duncan, and the way in which he has met and controverted the objections to the recognition of foetal gravita- tion as a cause of position in utero, must carry considerable weight. It is quite evident that gravitation cannot be omitted from the several influences which determine the natural presen- tations of the foetus. The latest exponent of the theory which refers the natural presentation of the foetus to Instinctive and Toluntary move- 276 VIEWS RESPECTING THE FCETAL POSITION. mcnts on the part of the foetus itself, is M. Paul Dubois, who wrote a very able es3ay upon this subject in 1832. Dubois, excluding the influence of gravitation, compared the power which leads to the assumption of the position of the foetus with the head opposite to the os uteri, to the instinct which leads the bird to build its nest. He supposed that the foetus, moved by an irresistible impulse, effects the descent of the head, so as to render it the presenting part, by a series of small volitions or spontaneous determinations, occurring during the latter part of pregnancy. The chief argument in favor of the possession by the foetus of sensation, and possibly of volition, urged by this able obstetrician, is drawn from the harmony which he believed to exist between the movements of the foetus and the objects which they were presumed to effect. Had he written after the reception of Dr. Marshall Hall's great discovery of the spinal or physical movements, as distinct from the cerebral or physical motor actions of the animal economy, he would probably have referred the motor powers of the foetus to reflex action, instead of to instinct or volition. Dr. Simpson, coming after Dubois, has taken reflex action as the clue to the fcetal movements, and has shown that we have no evidence whatever that the foetus possesses any manifestations which may not be attributed to purely physical causes. Dr. Simpson, in a series of elaborate and original papers in the London and Edinburgh Monthly Journal for 1849, main- tains that the foetus in utero is subject to a constant succession of Reflex Motor actions, which are the chief cause of cephalic presentations. Dr. Simpson recognizes the ovoid outline of the uterus, and the ovoid shape of the foetus, as greatly tending to maintain the foetus in the uterus with the smaller end of the ovoid downwards; but he does not consider that the relations between the form of the foetus and the form of the uterus would of themselves be sufficient to produce the position, with the head over the os uteri. He believes, on the contrary, that " the regulating vital power guiding it to the assumption of that normal position in which its figure corresponds as exactly as possible to the figure of the uterine cavity, consists of a succes- sion of reflex or excito-motory movements of an adaptive kind on the part of the foetus, excited by impressions made on its external surface." The physical stimuli causing these move- Simpson's views of the fcetal position. 277 ments are referred to temporary irritations of the cutaneous surface of the foetus by contact with the uterine walls, when the foetus is thrown out of position by any movements or change of position on the part of the mother, such as rising or lying down, stooping, and other motions of the body. Dr. Simpson points out, that the soles of the feet, the knees and sides, parts which in the adult are marked excitors of reflex action, and which in the young child yield the sensation of tickling, are precisely the parts exposed to irritation in the foetus. Arguing from these considerations respecting the cause of the normal presen- tation of the head, Dr. Simpson contends that the causes of mal-presentation are the occurrence of labor before the reflex actions have established the natural position; the death of the foetus—in other words, the loss of its adaptive reflex actions; the causes altering the shape of the foetus or uterus, or physical Fig. 80. Position of twins in utero. sources of displacement, such as by hydrocephalus, montrosities, dropsy of the amnion, uterine spasm, tumors of the uterine walls, placenta praevia, distortions of the pelvis, and accidents occurring to the mother. Finally, Dr. Simpson indicates that in the reflex movements of the foetus lie the reasons of the rarity of positions of the fcetal head in the direct diameters of the brim of the pelvis, and their great frequency in the oblique 278 relative frequency of positions. diameters, particularly the right oblique diameter, and the greater relative frequency of occipito-anterior to that of occipito- posterior presentations. In these papers, Dr. Simpson refers to Fig. 81. Adaptation of hydrocephalic fetus. Fig, 82. Adaptations of foetus and uterus in breech presentation. the influence of tone as moulding the form and figure of the foetus, but he takes no account of the uterine movements in the latter part of pregnancy, and repudiates gravitation as a cause of TONE IN THE FCETUS. 279 foetal position. Dr. Simpson illustrates his views by a series of admirable engravings, showing the outline of the uterus and the foetus under different conditions. In my lecture " On Parturition," published in 1848, before the appearance of Dr. Simpson's papers, while discussing the abdominal movements of pregnancy, I endeavored to draw a dis- tinction between the movements of the foetus and those of the uterus. I pointed out that many of the movements commonly attributed to the foetus really belonged to the uterus. I ad- mitted that the foetus moved in ^obedience to reflex stimuli, but I supposed these reflex movements to be faint and obscure, because of the provisions which shield the foetus from reflex ex- citation. I believe I underrated the extent and influence of the foetal movements; but after the best consideration I have been able to give the subject, I think Dr. Simpson has attributed to the reflex movements of the foetus results, in the production of which other agencies play a very considerable part. The ovoid shape of the foetus, towards the end of gestation, depends in part upon the form of the uterus, and in part upon the muscular condition of the foetus itself. As I pointed out, in 1848, the foetus in utero, is, when unexcited and at rest, under the spinal influence of what Dr. Marshall Hall calls " Tone," or the continuous influence of the vis nervosa; that principle by which the sphincters are kept closed in after life, and which causes the contractions in limbs which are deprived of the in- fluence of volition in cerebral paralysis. Under this influence, the stronger flexor muscles having more power than the exten- sors, the body of the child is slightly bent as it is in the adult, in the recumbent position when volition is at rest, as in sleep, and the arms and legs are contracted. This contracted state of the arms and legs, in the foetus, depends upon an active condi- tion of rigidity; and we see that, after birth, it is often difficult to straighten the limbs—their natural position—until the influ- ence of volition has gradually acquired power, being an approach to that which obtains in utero. In the lower animals, the limbs, under the same influence, are straight instead of curved, the fore-limbs especially being stretched out rigidly on each side of the head. Tins is as necessary to healthy parturition in the lower animals, as the contraction of the limbs in the human foetus. The principle of tone, then, in the human foetus, tends 280 EXPERIMENTS ON THE FOETUS. to preserve the ovoid shape of the foetus, and it also tends to keep the child perfectly still and motionless. This continued influence of tone tends to maintain the foetus in a passive state, and under the influence and control of the containing uterus. It is quite as important in maintaining the position of the uterus as the reflex actions are in restoring it, when this has been dis- turbed by a change of position, etc. In 1850, I performed some experiments with a view to deter- mine the particular reflex movements manifested by the foetus in utero under irritation. I took a rabbit nearly ready to kindle, and having placed it under chloroform, and fastened it to a table, opened the abdomen so as to expose the uterus. I now made an incision into the uterus opposite the situation of a foetus, so as not to wound the amnion, or to interfere with the placental attachment. In this way the foetus was exposed in the transparent amnion without being injured in any way, the cir- culation in the cord not being at all interfered with. I found that when any part of the foetus was irritated through the amnion, the foetus would draw up its limbs, and shortly afterwards returned to the ordinary quiescent state. The one movement which constantly occurred, whether the ears, extremities, or tail were pinched, was a movement of the head, as in respiration. The mouth was opened and shut again once or twice, in a way somewhat similar to the movements of the mouth and head of a kitten while drowning. No liquor amnii appeared to be swallowed, and no movements of deglutition were attempted. I repeated the experiment several times with the same result. The respiratory movement affected the whole of the upper part of the body, but no inspiration or expiration occurred. It appeared to me that these imperfect respiratory movements must occur with every movement of the foetus, and that move- ments of respiration do not occur, as is supposed, for the first time, after birth. This would account for the curious pheno- mena of Vagitus, in which, when air reaches the mouth of the foetus, a cry is produced before the expulsion of the head of the child. The supposed reflex foetal movements of pregnancy have been felt in cases of amyelitic foetuses, when the spinal marrow, and as a consequence, all reflex movements, are absent. I quoted in my former Lectures a case of this kind from Lallemand, in MOTION OF THE FOETUS, REFLEX UTERINE ACTION. 281 which the spinal marrow was entirely wanting, but in which the supposed foetal movements were present. Since that time two cases have been supplied to me, oiie by Mr. Hoadley Gabb, of Hastings, and the other by Professor Zaviziano, of Corfu, in which there was congenital absence of the brain and spinal marrow, but the intra-abdominal movements of pregnancy were profuse in both cases. I pointed out that in the state in which the foetus exists in utero, constant excitation and motion would exhaust the foetus. Professor Simpson compares the foetus in utero to a decapitated frog, but the frog in this condition is speedily destroyed by excitation. I mentioned that in the com- mon experiment of placing the hand in cold water, and then applying it to the uterus, the resulting movements must neces- sarily be reflex movements of the uterus, excited by the irritation of the excitor nerves of the skin, which we know happens very readily after labor. It is impossible that the influence of this cold hand could be transmitted to the foetus through the abdominal walls, the uterus, and the liquor amnii. The same explanation applies to the movements caused by taking food or drink into the stomach, or the sensation of hunger. The move- ments excited by touching the feet, in footling cases, are feeble. The motions produced by lightly irritating the feet of a sleeping infant are inconsiderable, and the soles of the feet are well known to be the most excitable part of the cutaneous surface." We may observe after death evidence that in some cases the foetus has been quiet for some time before birth. The legs of the foetus may indent each other when they have lain across, or the mark of the hand is left on the side of the head. If the movements of the foetus were so considerable as have been sup- posed, we should expect incessant movements during labor. No experiments can imitate, even to a tolerable degree, the conditions of the foetus in utero. Suspending the mature dead foetus in a similar fluid with the liquor amnii, when placed within a vessel having the shape of the gravid uterus, fails in many of the essential conditions belonging to the living foetus in utero. In the early development of the embryo, the limbs are deficient in muscular power, and do not assume any definite form. The nervous system has hardly commenced its control over the as yet feeble muscles. The quantity of liquor amnii is very large in proportion to the size of the uterus, and the uterus is 282 CHANGE OF POSITION OF THE F02TUS. circular rather than ovoid in shape. We have to consider these elements as slowly altering from day to day in an almost in- itio. 83. Foetus and uterus at fifth month. appreciable manner, during the middle and latter months of pregnancy, and while the foetus is gradually taking up its ulti- mate position. The limbs of the foetus enlarge, becoming subject to the influence of the vis nervosa, and under the influence of tone, the arms and legs, particularly the latter, become con- tracted, so as to form the foetal ovoid. During this time, the relative quantity of the liquor amnii diminishes, so that at the full term the liquor amnii scarcely does more than fill up the interstices left between the foetus and the uterus. Synchronously with these events, the uterus itself, by the development of the cervix, changes from the circular to the pyriform or ovoid shape. With this change of shape, the uterus acquires more power of muscular contraction, and becomes the subject of reflex and peristaltic actions. The contractions of the uterus neces- sarily exert a moulding or adaptive influence upon the foetus, poised lightly as it is in the liquor amnii, and moved within the limits of its prison by the slightest impetus. These causes are probablyT aided by the reflex movements of the foetus itself. Under irritation, the limbs of the foetus strike out, but only to return more closely to its ovoid shape, and to accommodate it- self as accurately and easily as possible to the uterine cavity. All these influences, combined with the effects of gravitation SPINAL PRINCIPLE PREDOMINANT. 283 and of the inclined planes upon which the foetus rests in the up- right and recumbent positions of the mother, arrange and preserve the foetus in the normal position with the head at the FlGL 84 Form of uterus in deformed pelvis. os uteri. No single power, however, gives its attitude or posi- tion to the foetus, and it is difficult, amidst such a number of adaptations, all contributing to the same end, to single out the most important. If we give the predominance to any one of them, I think the spinal principle of Tone must be considered as the most influential, and it is to the absence of this, more than of any quality, that we must attribute the irregular presentation of dead children. LECTURE XIX. THE BONES, ARTICULATIONS, AND LIGAMENTS OF THE FEMALE PELVIS. Gentlemen,—The Pelvis consists of four bones, the two Ossa Innominata, the Sacrum, and the Coccyx. In the female pelvis the last lumbar vertebra also requires to be considered in con- nection with the above, as contributing to form the framework of the theatre in which the principal events of natural and mor- bid parturition are performed. Up to the age of puberty each Os Innominatum consists of three distinct bones, the Ilium, Ischium, and Pubis, which are separated from each other at the acetabulum by cartilaginous divisions (Fig. p. 285). After this time the bones become united through the medium of a Y-shaped bony deposit. Epiphyses are also slowly formed upon the crest of the ilium, the anterior and inferior spine of the ilium, the tuberosity of the ischium, and the pubis at the symphysis. These additions increase the size of the bones which form the pelvis, and strengthen the principal points for the attachment of muscles. When the two innominate bones are placed together, they form the anterior and lateral portions of the pelvis. x The obstetric points in the anatomy of the os innominatum are numerous and important, but these are of course chiefly confined to the internal surface of the bone. To the crista of the ilium the chief of the abdominal muscles concerned in labor, the internal oblique, external oblique, and transversalis are attached. Other muscles concerned in parturition are attached, the pyrami- dalis and the rectus abdominis to the tuberosity of the pubis; the levator ani to the pelvic portion of the pubis ; and the muscles which contribute to form the perinaeum to the tuberosity of the 284 OS INNOMINATUM. 285 ischium. The iliac fossa, covered by the iliacus internus muscle, contributes to the support of the lower segment of the gravid uterus in the latter part of pregnancy, before the head of the foetus has descended into the pelvis. A line running from the promontory of the sacrum to the tuberosity of the pubis, the Division between the ischium, ilium, and pubis. linea ilio-pectinea, forms the boundary between the true and false pelvis, or between the cavities of the pelvis and abdomen. This line also marks the greater part of the pelvic brim. At the junction of the ilium with the pubis, a prominence is met with upon the ilio-pectineal line, which is called the ilio-pectineal eminence. The inferior and slightly everted border of the descending ramus of the pubis, forms, with its fellow of the opposite side the arch of the pubis. Between the body and ramus of the ischium and the ascending and horizontal portions of the pubis an oval opening, the obturator foramen, is seen. The smooth inner surface of this ramus, and the smooth portion of the inter- nal surface of the ischium are the surfaces over which the pre- senting part of the foetal head glides in parturition, and which give it its direction as it emerges under the pubic arch. The tuberosity of the ischium and the spinous process of this por- 286 SACRUM. tion of the os innominatum contribute to form the outlet of the pelvis. Behind the spine of the ischium are seen the anterior and superior spinous processes of the ilium, between which the two sciatic foramina are formed. The whole of the three bones entering into the composition of the os innominatum contribute to form about three-fourths of the pelvic brim. _ The internal surface of the Sacrum is of great obstetric sig- nificance. It forms the posterior part of the pelvic walls, being articulated on either side with the ossa innominata. Above, it is united with the fifth lumbar vertebra, and below with the coccyx. Its upper portion forms, with the last lumbar vertebra and the inter-articular cartilage, the promontory of the sacrum, or sacro-vertebral angle, the angle being formed by the devia- tions of the line of the lumbar vertebrae, and the line of the upper part of the sacrum. The anterior aspect of the sacrum is smooth and concave from above downwards. The depth of the sacral curve is shown by two lines, one drawn from the promon- tory to the point of the sacrum, and the other at right angles from this line to the middle of the third sacral vertebra. Innominatum. From side to side, the pelvic surface is less concave, particu larly at its extremities, where it is slightly convex. It is marked by four transverse lines, indicating its original division into five COCCYX. 287 rudimentary vertebrae. These divisions exist, the bones being divided by cartilage and inter-vertebral matter, until after the age of puberty, when ossification begins between the lowest por- tions, and ascending upwards, the bones become one osseous mass about the age of thirty. It presents on each side four inter- vertebral foramina, for the passage of the anterior branches of the sacral nerves. Besides the great angle or promontory of the sacrum, a lesser angle is formed at the union of the sacrum and the coccyx, when the coccyx is bent backwards at the time of parturition. The Coccyx generally consists of four pieces of bone articulated together until a late period of life, when they become ossified into one mass. These bones continue in the direction of the lower part of the sacral curve, so that they project downwards and forwards, their internal surface being smooth and concave. During the child-bearing era the bones of the coccyx move Section of sacrum and coccyx. slightly upon each other, and considerably upon the sacrum, with which the first bone is articulated. The first piece of the coccyx is the only one presenting any marked characters. It presents above a smooth surface, which is in apposition with the last bone of the sacrum. From the posterior and lateral sides of this surface small cornua project, which rest upon the sacral cornua. Beneath this process a small nodule, sometimes con- 288 BONES OF THE COCCYX. tracted into a foramen, transmits the last sacral nerve. The bones of the coccyx diminish in size from above downwards, so that the last piece is a mere nodule. Attachments exist between the coccyx and the coccygeus muscle, the levator ani, the gluteus maximus, and the sciatic ligaments on each side, and the sphincter ani at its extremity. The coccyx has the power of movement backwards or forwards to the extent of an inch. When moved forward or elevated, it decreases the pelvic outlet; but when depressed and drawn backwards, it increases its area. This bone is moved forwards by the contraction of the levator and sphincter ani; and backwards by the contraction of the lower fibres of the .gluteus maximus, when the thighs are fixed, the coccygeus, and the dilatation of the sphincter ani. The depression of the coccyx is carried, however to its utmost point by the mechanical pressure of the foetus as it passes the pelvic outlet. The Fifth Lumbar Vertebra articulates with the upper sur- face of the sacrum, and contributes, as already mentioned, to form its angle or promontory. This is effected by the lower surface of the last lumber vertebra being oblique instead of flat, Sacrum and coccyx. the anterior portion of the body being thus rendered much deeper than the posterior. In cases of deformed pelvis ARTICULATIONS AND LIGAMENTS OF THE PELVIS. 289 this bone may become of great importance, and the other lum- bar vertebrae also may have an immediate bearing upon the pelvis. Through the medium of the lumbar fascia, the lumbar vertebrae give attachment to the transversalis and the internal oblique muscles. Some anatomists consider that the fourth lumbar vertebra also forms part of the false pelvis, in ligament- ous preparations, and in the living subject, because of the liga- mentous connection which exists between the transverse process and the crest of the ilium. Fifth lumbar vertebra. The Articulations and Ligaments which unite the bones of the pelvis, not only give the necessary strength to this part of the body, with reference to the support of the trunk and the movements of the lower extremities, but they contribute largely to render the pelvis a cavity fitted to contain and preserve the pelvic viscera, and a canal for the jpassage of the foetus in par- turition. The joints and articulations are so arranged that the internal surface of the pelvis is rendered smooth; but externally everything is subsidiary to strength, and numerous prominences are observed. Bony processes, ligaments, and the attachments of muscles are all made to contribute to this object. The whole pelvis may be compared to a nest, in which the rough materials are accumulated on the outside, the cavity being rendered as smooth and even as possible. The joints to be considered are the Lumbo-Sacral, Sacro-iliac, Sacro-Coccygean, and Pubic ar- ticulations : they all belong to that class of joints termed amphi- arthrosis. The ligaments are very numerous, and connect the bones of the pelvis at other points beside those at which the bones are in articular opposition. The vertebral surface of the sacrum articulates with the last lumbar vertebra, by means of a wedged-shaped mass of fibro- 19 290 UNION OF THE PELVIC BONE8. cartilage, the thickest part of the wedge being in front, and in- creasing the effect of the peculiar slope of the body of the last lumbar vertebra. This cartilage, which resembles in structure the inter-vertebral cartilages, really constitutes the most promi- nent point of the promontory of the sacrum, as it is termed. That is to say, if the finger be introduced into the vagina for the purpose of examining the capacity of the pelvis, the projecting point of the upper and posterior part of the brim is felt at the anterior part of this cartilage. The common anterior vertebral ligament passes in front of the lowest lumbar vertebrae, and ex- tends downwards over the front of the sacrum and coccygeal bones. The transverse process of the last, and, according to some authorities, the fourth, lumbar vertebrae, are connected with the upper and external portion of the sacrum by a thick, short, and strong ligament, called the lumbo-sacral, or sacro-verte- tebral ligament. With the exception of this ligament, and the shape of the cartilage above described, the ligaments uniting the sacrum to the vertebral column are the same as those connecting the several vertebrae with each other. The Sacro-iliac Symphysis unites the articular surfaces of the sacrum and ilium, both of which are covered by a layer of cartilage presenting numerous inequalities when not in apposition. The sacral layer of cartilage is somewhat thicker than that be- longing to the ilium. The union of these bones is strengthened and rendered complete by the ilio-lumbar and the anterior and posterior sacro-iliac ligaments. The ilio-lumbar extends from the transverse process of the fifth lumbar vertebra, and the back of the sacrum, to the crest of the ilium, near the posterio-supe- rior spinous process. The anterior sacro-iliac ligament extends between the anterior surfaces of the ilium and sacrum, in the form of a thin irregular layer. The posterior sacro-iliac is strong- er, consisting of several sets of fibres, extending obliquely and transversely from the rough surface of the sacrum to the poste- ior surface of the ilium. The coccyx is united to the sacrum by a thin fibro-cartilagin- ous layer interposed between the articular surfaces of the two bones, and by an anterior and posterior ligament—the latter being of considerable thickness. The small bones of the coccyx are also joined to each other by thin plates of cartilage, and anterior and posterior ligamentous bands. Some anatomists describe the LIGAMENl'S OF THE PELVIS. 291 existence of small synovial sacs in cases in which these bones move more freely than usual upon each other and upon the sacrum. The two Sacro-sciatic Ligaments, great and small, require notice in this place. These unite the ilium, the sacrum, and the coccyx to the ischium, and contribute to strengthen the posterior articulations of the pelvis ; but they are of more importance as a portion of the canal and outlet of the pelvis itself, than as forming part of the pelvic articulations. The greater or posterior sacro-sciatic ligament extends from the posterior and inferior surfaces of the ilium and the posterior part of the sacrum and coccyx, to the tuberosity and ramus of the ischium. This ligament is expanded at its extremities, par- ticularly at its posterior attachments. The small or anterior sacro-sciatic ligament extends from the side of the sacrum and coccyx to the spinous process of the ischium. At the sacro- coccygean attachment the fibres of the ligament are in apposi- tion with the middle part of the posterior ligament; but in pass- ing the spinous processes, the direction of the anterior ligament crosses that of the posterior. The attachment of the anterior ligament to the sacrum and coccyx is broad, but its attachment to the spinous process is smaller, so that the whole ligament is trian- gular in shape. The space between the anterior and posterior liga- ments and the spine and tuberosity of the ischium constitutes the Sacro-sciatic ligaments and ilio lumbar. 292 MOVEMENTS OF THE PELVIC BONES. small sacro-sciatic foramen ; while the large sacro-sciatic foramen is formed by the sacrum and ilium, and the sacro-sciatic ligaments. The obturator-fascia ligament may be mentioned here, as being concerned in the formation of the pelvis, without any reference to its articulations. It is a fibrous membrane filling up the ob- turator foramen, except at the upper part, where the obturator nerves and vessels make their exit. The obturator fascia is connected with the great sacro-sciatic ligament by the process sent up from the tuberosity of the ischium. The Symphysis Pubis consists of the articular surfaces of the pubic bones, an inter-articular cartilage, anterior and posterior ligaments, and the superior, and sub-pubic, or triangular, ligaments. The inter-articular fibro-cartilage is composed of concentric lamellae,' This cartilage itself is imperfectly divided into two parts, one for each osseous surface, frequently con- taining a viscid pulp in the central space between them. The posterior ligament is the most indistinct; the anterior consists of numerous thick decussating fibres, which cover the symphysis. The superior pubic ligament consists of ligamentous fasciculi, which fill up the small space between the bones above the inter- articular cartilage at the upper part of the symphysis. The sub- pubic or triangular ligament is the most important. It is thick and crescent-shaped, attached to the descending rami of the pubis and the lower part of the inter-articular cartilage. Its inferior border is smooth and arched, contributing to form the angle or arch of the pubis, one of the great obstetric points of the pelvis. With the exception of the coccyx, the Movements of the Bones of the Pelvis upon each other in the unimpregnated state are extremely limited. Some authorities have maintained that during labor all the pelvic symphyses are relaxed to a slight v- extent, while others have believed that the joints remain entirely unaltered at this time. This supposition led to the now aban- doned operation of Sigault, for the division of the symphysis pubis in cases of contracted pelvis. Some have even believed that during gestation osseous matter is absorbed from the pelvis and carried into the circulation to supply the wants of the foetus. Others contend that no change whatever occurs in the bones or joints of the pelvis in the course of pregnancy and parturition. We know, however, as Denman pointed out, that in rare cases the sacro-iliac and pubic articulations become so relaxed as to EVIDENCE OF DESIGN IN THE FEMALE PELVIS. 293 cripple the subjects of this affection for a considerable time after labor. It is also known from dissections of women dying during or immediately after labor, that the cartilages of the joints of the pelvis are found to be softer and more vascular than usual at this time. Many of the lower animals are unable to support themselves firmly in the standing position previous to and during parturition, in consequence of a relaxation of the joints of the pelvis ; and Mr. Robertson has pointed out that in the guinea-pig, the pubic symphysis is widely separated at the time of labor, to admit of the passage of the young. These facts afford good reasons for believing that in many cases a slight amount of relaxation of the pelvic articulations does take place in the human female during delivery. The attachments and u- action of the abdominal muscles are such, that during the expul- sive stage of labor the outlet of the pelvis becomes slightly en- larged. Perhaps no part of the human skeleton, rife as the whole is with adaptations, evinces more evidences of design than the bones of the female pelvis. The progress of ossification shows this in an eminent degree. Up to the time of puberty the car- tilaginous division between the ilium, ischium, and pubis is com- plete. Under the stimulus of the ovaria, the pelvis enlarges considerably at, and previously to, the occurrence of the cate- menia, and the separation of the bones which compose the pelvis greatly facilitates those operations of growth, by which its cavity is expanded to the mature standard. In the other parts of the body there is no instance of any such sudden change after the time of birth, not even in dentition, as that which oc- curs in the pelvis and its contained organs during the two or three years in which puberty is prepared for and completed. The development of the sterile girl into the fruitful woman is almost as striking as the metamorphoses which occur in the lower orders of creation. All the changes of this epoch have for their great object the preparation of the organism for the func- tions of impregnation and childbearing. Of these, the expan- sion of the bones of the pelvis, before the union of the three v parts which compose the os innominatum, the bony deposit be- tween the pubic bones at the symphysis pubis, the slow union of the bones of the sacrum, the formation of the numerous epiphyses which enlarge the pelvis and contribute to its strength 294 ANATOMY OF THE NORMAL PELVIS. at and before the era of puberty; and the ossific union of the different parts of the coccyx and of the whole bone with the sacrum, only after the function of childbearing has altogether ceased, are amongst the most remarkable. The individual bones and ligaments which enter into the com- position of the pelvis having received a detailed notice, attention J will now be directed to the interior of the pelvis, and to the nor- mal relations of the salient osseous points of its exterior anatomy. Under the first head will be included the Pelvic Planes, Axes, Angles, Diameters, and Canal, while the second will refer to cer- tain external measurements, a knowledge of which is necessary to a ready diagnosis of special internal malformations, or general alterations of dimension and configuration. I have reserved the consideration of the Normal Pelvis, to the present time, instead of introducing it into the early part of the work, in order to con- nect it with the anatomy of the Foetal Head, and the Mechan- ism- of Labor, which will form the subjects of the two next Lectures. As already stated, the pelvis is divided into two parts, a false and a true pelvis, the first situated above, and the second below, the linea-ileo-pectinca. The relations of these divisions of the whole pelvis to utero-gestation and parturition are very unequal, '. and in cases where the false pelvis is malformed, the distortion of the true pelvis co-exists to such an extent as to render the deviations above the brim comparatively unimportant. We must look for the interest of the false pelvis, not in its immediate relations to the passage of the foetus through the pelvic canal, but in its functions as the supporter of certain viscera, as a fixed point for the action of numerous muscles concerned in parturi- tion, and as a tolerably correct indicator of the condition of the true pelvis. The true pelvis, or bassin petit, as it is termed by French obstetricians, is situated below the linea-ileo-pectinea, which PELVIC DIAMETERS. 295 circumscribes its superior orifice or inlet, and has its inferior opening or outlet, bounded in part by osseous, and in part by Tig. 85. ligamentous structures. In the middle line posteriorly the out- let is formed by the coccyx, and by the great sacro-sciatic liga- ments laterally and behind; the tuberosities of the ischia are its extreme lateral boundaries, and the conterminous rami of the ischia and pubes form its anterior-lateral confines. The pelvic Fig. 86. Brim of pelvis. Transverse and oblique diameters marked. canal lies between the above limits, and within this canal are situated the rectum, bladder, and ureters; the internal iliac arteries and veins, with their subdivisions ; the lymphatics ; the sacral plexus in whole, and the lumbar plexus in part; and cer- 296 SCREW FORM OF THE INNER PELVIS. tain muscles visceral and femoral. In the unimpregnated female, it also contains the uterus and ovaries, and during utero- gestation, a varying portion of the lower portion of the gravid uterus and its contents. The Diameters of the pelvis are measurements taken in the three planes which have been described. The other dimensions necessary to be known are the depths of the pelvis at cfifferent points, and the distances between several of its»spines and tube- rosities. Beginning with the diameters of the superior plane or inlet, we have the long or transverse diameter, the antero-poste- i rior or conjugate diameters, and the right and left oblique dia- meters. In the mid-plane we have the same diameters to consi- der, but the oblique is now the longest diameter. In the infe- rior plane, the longest of the diameters is the antero-posterior. In referring to the statements of the most eminent authorities, an immense variety of measurements will be found, but the range of variation, with few exceptions, is not very great; and with regard to the greatest extremes, nothing is met with that does not probably result from the accidental omission or admission of very large or very small pelves into the calculation. The Depth of the pelvic cavity or canal varies greatly in different parts of the pelvis. Behind, it measures from five to six inches from the sacro-vertebral angle to the point of the coccyx; from the linea ilio-pectinea to the tuberosity of the ischium, : three inches and three-quarters; and from the crest of the pubis to the pubic arch, from an inch and a half to two inches. At the brim of the pelvis, the antero-posterior diameter, from the sacro-vertebral angle or promontory, to the crest of the pubis, measures four inches in the dried state. The transverse diameter measures from about four inches to five inches and a quarter. The measurement of the oblique diameter from the sacro-iliac symphysis to the ilio-pectineal eminence, is from four and a half to five inches. In the cavity of the pelvis, from the middle of the sacrum to the pubic symphysis, the antero-pos- terior diameter is as nearly as possible four inches and a half. The oblique diameter, from the middle of the great sacro-sciatic foramen to the obturator ligament is five inches. The transverse diameter on the same plane, between the two ischii is about four inches and three-quarters. At the outlet or inferior strait of the pelvis, the diameters are as follows : DIAMETERS OF THE PELVIS. 297 From the arch of the pubis to the extremity of the coccyx, antero-posterior, four inches and a half—but the mobility of the coccyx increases this by nearly an inch; between the sacro-sciatic ligament and the ascending ramus of the ischium, oblique, about five inches; between the tuberosities of the ischii, transverse, four inches. Thus, at the brim the longest diameter is the transverse, the shortest is the antero-posterior. In the middle of the pelvis, the oblique diameter is the longest, and the shortest is the an- tero-posterior. At the outlet, the antero-posterior is the long- est, and the transverse the shortest diameter. When the soft parts are in apposition with the bones, the oblique diameter of the brim is somewhat longer than the transverse. A line carried round the brim of the pelvis measures about fourteen inches. An average struck from the combined observations of Dun- can, Burns, Monro, Meckel, Watt, Velpeau, Moreau, Boivin, Baudelocque, Ramsbotham, Rigby, and Wood, gives us the following results :— Transverse. Oblique. Ant. posterior. Superior Plane........5.2..............4.8..............4.25 j Middle Plane________4.75..............5.2..............4.7 £ Inches. Inferior Plane........4.2...............................5.0 ) It is this change in the longest diameter of the pelvis, from the transverse to the oblique, and from the oblique to the an- tero-posterior, which gives to the pelvis the principle of the Screw—an idea we shall have to develop more at length when we come to the mechanism of labor. The Planes of the Pelvis are imaginary levels extended between some of its corresponding points, the inclination of ^ which to each other and to the horizon it is important to know. Only two of these planes have been generally deemed worthy of particular attention—namely, a superior and inferior plane, or plane of the inlet and outlet; but it is necessary to consider a third plane, situated between the other two, and which may be termed the mid-plane. To this plane especial study should 298 PELVIC BRIM. be directed, because it is here that the rotations of the foetal head are impressed upon it, and here, under slight deviations Fig. 87. Outlet of pelvis. Antero-posterior and transverse diameters marked. from the normal condition, serious obstacles to parturition are encountered. Tlie plane of the inlet, or superior plane, is bounded by the linea-ileo-pectinea, and is inclined to the horizon at an angle of v/ about 60° in the female (Naegele), 65° in the male (Weber). That is to say, in the erect posture, and in the unimpregnated condition, these are the inclinations of the pelvic brim, inlet, or superior plane. During pregnancy, and more particularly towards the end of utero-gestation, when the weight of the gra- vid uterus and enlarged breasts upon the anterior arms of the levers represented by the ossa innominata, the obliquity of the pelvis is diminished by the involuntary assumption of a position similiar to that taken by persons in walking down a hill. The amount of diminution cannot be stated with precise accuracy, as it varies according to the length and flexibility of the spine, as well as the mobility of the sacro-iliac articulations, but it fre- quently amounts to several degrees. There is an evident adap- tation of means to an end in the greater obliquity of the female as compared with the male pelvis, the approach of the internal surface of the symphisis pubis to the horizontal position being manifestly conducive to the support and retention of the compa- ratively heavy pelvic viscera of the female, and fitted to coun- teract the tendency to prolapse caused by the greater area of i PELVIC CANAL. 299 the pelvic canal. This might seem to be contradicted by the diminished obliquity which obtains during pregnancy. The Fig* 88. A, Plane of the inlet. B, Mid-plane. C, Plane of the outlet. gravid uterus rises, however, out of the pelvic cavity before the obliquity is materially altered, and prolapse thus becomes mechanically impossible, from the increased size and elevation of the uterus, when the ordinary provisions for support cease to be in operation. The elevation of the sacral promontory above the upper margin of the symphisis pubis, in the unimpregnated female, will of course depend partly on the obliquity of the pel- vis, and partly on its dimensions. In the well-formed female pelvis, it is usually from three inches nine lines to three inches ten lines; and in the upright position, the sacral portion of the brim is a little below the antero-superior iliac spine. It is necessary to study the relations of the superior plane of the pel- ^ vis to the spinal column. The pelvi-vertebral angle—that is, the angle subtended by the superior plane of the pelvis, and the lumbar portion of the spine, forms an angle of about 150°. This angle varies slightly in different individuals, but is dimi- nished somewhat by the anteflexion of the spine, and drawing up of the inferior extremities, which obtains in the obstetric position. The study of the above particulars may be facilitated by means of a diagram. (Fig. 89.) 300 BOUNDARIES OF THE PELVIS. The mid-plane, or strait, of the pelvis, unlike the superior plane, is not bounded by a line, all the points of which lie in the Fid. 89. T) A B, Horizon. C D, Vertical. A B I, Angle of inclination of pelvis to horizon, equal to 60 deg. B I C, Angle of inclination of pelvis to spinal column, equal to 150 deg. C IJ, Angle of inclination of sacrum to spinal column, equal to 130 deg. E P, Axis of the inlet. L M, Mid-plane of the middle line. N, Lowest point of the mid-plane at the spine of the ischium. same plane, and the term plane must not be taken therefore in an exact and mathematical, but in an obstetric and conventional sense. Its boundaries may be stated as follows : Commencing at the symphisis pubis anteriorly, at about the level of the upper margin of the obturator foramen, it crosses the obturator mem- brane immediately below the point of the exit of the obturator nerve and artery; from thence it descends the spine of the ischium along the oblique ridge on the inner surface of that bone. It then traverses the lesser sacro-sciatic ligament, and ascends to the level of the lower portion of the third piece of the sacrum. The straight line, L M, in the diagram represents its level in the mesial line ; its lowest point is indicated by the letter N, situated at the lowest part of the curved line, and this PLANES OF THE PELVIS. 301 corresponds to the apex of the ischial spines. The general incli- nation of this plane to the horizon is considerably greater than that of the superior plane—in other words it makes a less angle with the horizon, the difference being about 20°. The impor- tance of the study of this plane will be more particularly dwelt on when speaking of the canal of the pelvis. (Fig. 90.) Fir 90. A, Axis of Superior plane. B, Axis of Mid-plane. C, Axis of Inferior plane. D, Axis of Canal. E, Horizon. The inferior plane, plane of the outlet, or inferior strait, is commonly described as extending between the lower margin of the symphisis pubis anteriorly, and to the tip of the coccyx pos- teriorly. There are, however, valid reasons for dismissing the coccyx from our calculations on this head; for being movable, and potentially endowed with elasticity through the medium of its connection with the perinaeum, any influence it exerts upon the progress of labor partakes of the nature of a force applied from without, and differs toto coelo from the rigid resistance of all other parts of the pelvis. The motion enjoyed by the coccyx is so great, that before it has reached its limit it ceases to influence the antero-posterior diameter of the outlet, and the mechanical conditions under which the foetal head escapes from the pelvis 302 AXES OF THE PELVIS. are then imposed by the apex of the sacrum. This is proved by the following measurements: In a large female pelvis, the antero posterior diameter of the outlet, measuring from the tip of the sacrum, is 4.5 inches, and from the tip of the coccyx, 3.625. The amount of motion enjoyed by the coccyx equals one inch—that is to say, the coccyx can be pushed back one inch from its ordinary situation by the pressure of the foetal head and the action of the muscles in connection with the coccyx. If we add this inch to the ordinary diameter, 3.625, we have 4.625 as the distance from the tip of the coccyx to the lower border of the symphisis pubis. As this is greater than 4.5 inches, the distance from the last mentioned point to the extremity of the sacrum, it is clear that the sacrum, and not the coccyx, bounds the outlet of the pelvis, and determines how large a body shall pass out of it. The incli- nation of the plane of the outlet to the horizon, if the measure- ment to the tip of the coccyx be taken, is, according to Naegele, from 10° to 11°. If the tip of the sacrum is taken as the osseous limit posteriorly, the inclination will not of course be so great, the angle being in this from 15° to 16°. The planes of the pelvis meet, if projected anteriorly, about 1.5 inch in front of and below the symphisis pubis. These several planes, it must be borne in mind, vary in their relation to the horizon and to the spinal column, but constantly preserve the same relations between themselves. The sacro-iliac articulations are not free enough to allow of any variation in the pelvic planes. As a corollary to this, it follows that the axes of the planes of the pelvis must be fixed and determinate, and the course of the fcetal head under normal conditions must be fixed and deter- minate also. The axes of the pelvis are certain imaginary lines, drawn at right angles to the several planes of the pelvis. The axis of the superior plane or axis of the inlet, if prolonged and produced superiorly, will emerge from the umbilicus, and, inferiorly, will impinge upon the anterior surface of the coccyx, near its point. This line makes with the horizon an angle of about 30°. The axis of the mid-plane, if produced inferiorly, will fall upon a point rather nearer to the anus than half the distance between the anus and the tip of the coccyx ; and superiorly, will issue some inches above the umbilicus. The angle made with the PELVIC AXIS, THE ARC OF A CIRCLE. 303 horizon by this line is about 50°. The axis of the outlet, when the point of the coccyx is not displaced by the egress of the foetus, falls from the promontory of the sacrum to midway between the tuberosities of the ischia, or to the anus if continued through the soft parts. The angle made by this axis with the horizon is about 80°. But, as already stated, it is better to con- sider the axis of the outlet as the axis of a plane extended between the inner margin of the symphisis pubis and the apex of the sacrum. Such a line would emerge superiorly, a little in front of the sacral promontory, and, below, would fall a little behind the anus. There would also be a small diminution of the angle made by the axis of the outlet with the horizon. This represents the actual state of things during labor, when the coccyx is moved back, and the differences just enumerated necessarily follow. (Fig. 90.) These axes are all of them of importance chiefly as they bear V upon the true axis of the pelvic canal which represents the path traversed by the foetus in its passage from the maternal nidus to the external world. The axis of the canal is a subject upon which very diverse opinions have been held, and most of them evidence a wish for diagrammatic perfection rather than a patient observation of Nature. The study of the axes of the pelvic planes of the inlet and outlet has led to much incorrect opinion, the axis of the canal being held to be identical with the axis of these two or three planes ; whereas, the axis of the canal is^. identical with every imaginary intermediate plane from the inlet to the outlet, at the point where the axis cuts the plane. One observation will show the fallacy of representing the axis of the canal by the axes of isolated planes. The axis of the outlet of the pelvis, and the direction of the axis of the lower part of the pelvic canal, are usually confounded together, whereas they are totally distinct. The axis of the outlet is down- wards and backwards, being at right angles with the inferior pelvic plane, while the produced inferior extremity of the axis of the canal, being the axis not of one plane but of many, looks downwards and forwards. It is difficult to conceive how such men as Muller and Roederer should have fallen into the error of making the pelvic axis a right line. Baug, Choulant, Carus, and Camper represent it by means of an arc de cercle ; and the circle of Cams finds favor at the present time with many obstet- • 304 VIEWS OF WRITERS ON THE PELVIC CURVE. ricians. Camper is, perhaps, the model of a mind addicted to diagrams; and, as is well known, he fell into diagrammatic vagaries about other things than obstetrics. A rougher idea, again, of the direction of the pelvic axis could hardly be given than by endeavoring to express it by the meet- ing of the inlet and outlet; yet this is held by some. Levret caught a glimpse of the truth when he proposed to represent the value of the pelvic curve by perpendiculars drawn from three planes. Had he said thirty or three hundred planes, he would have been nearer the fact, the axis of the pelvis being in reality, as already stated, a curved line, passing through the centre of every linear plane between the plane of the inlet and the plane of the outlet. Of all recent authors, Dubois leaves least to be Fib. 93. a 5, Axis of the path of the foetus through the pelvis, o, Coccyx, dd, Distended perinaeum. wished for in his description of the pelvic curve. We must bu careful not to dislocate the curve of the pelvis from its connec- tion with other parts through which the foetus passes. This curve is only complete when we have added to it the axis of the • AXIS OF THE INLET AND OUTLET. 305 uterus above and of the distensible soft parts below. Col- lectively, the parturient line is expressed by an irregular para- bolic curve, fixed from the brim of the pelvis to a line drawn from the inferior margin of the symphisis pubis to the apex of the sacrum, and variable from the fundus uteri to the pelvic brim, and from the outlet to the margin of the perinaeum, according to the position of the uterus, and the facility with which the coccyx is pushed back or the perinseum distended. The study of the axis of the inlet and of the outlet of the y canal has important practical bearings. In order that the uterus may act with the greatest efficiency in the first stage of the labor, where the motor force is required in the direction of the axis of the inlet, it is necessary that the axis of the uterus should correspond with the axis of the inlet. If the gravid uterus be anteflected or retroflected from the true position, the progress of labor is impeded. If the axis of the uterus approaches the hor- izon, the foetal head is impelled against the promontory of the sacrum ; if it approaches the perpendicular, it is urged against the pubes. The derangements of the axes of the uterus and pel- vis have the same effect as distortion of the brim, only the diffi- culty is easily remediable. By bending the spine upon the pelvis as in the usual obstetric position, we may depress the axis of the uterus ; and, on the other hand, if it requires to be raised, it is necessary to support the uterus with a bandage or place the pa- tient on her back. It is necessary that we should recognize the direction of the axis of the outlet in examinations ; in introduc- ing the hand into the uterus; in assisting the birth of the head; and in all traction in midwifery operations of every kind. The canal of the pelvis is the most important matter in [f relation to this assemblage of osseous structures, and it is espe- cially necessary to consider the walls of this canal, and the direction taken by the different portions of the pelvic parietes. It may be observed that the inner surface is made up of a num- ber of smooth inclined planes, and that the inclination of these planes is so arranged as to accomplish two principal objects; one, j a gradual alteration of the direction of the longest diameter of the canal: the other, a more sudden change in the direction of the planes themselves. Between the superior and middle planes of the are,a of the pelvis, we may observe in the pelvic walls of ^ the inlet four inclined planes: of these, one is formed by the 20 • 306 DEPTH OF THE FEMALE PELVIS. whole of the internal surface of the body of the pubic bones; and a second, by the upper half of the sacrum. The direction of both these inclines is downwards and backwards. The two other inclined planes are placed laterally, and are composed of* the ilia and ischia, terminating in the spinous processes of the ^ latter. The direction of these lateral spines is downwards, backwards, and inwards, so that at the spines of the ischia the walls of the pelvis approximate to each other more closely than they do at the commencement of the superior lateral planes, below the linea-ileo-pectina. The inclined planes of the outlet, as far as the bony pelvis is concerned, may be said to be five in number; one posterior and four lateral. The direction of the posterior, consisting of the lower half of the \,- sacrum and the adjacent portions of the sacro-sciatic ligaments, is also downwards and forwards. Of the lateral inclined planes of the outlet, two, consisting of the internal surfaces of the ischia, below the level of the spinous processes, terminate in the tuberosities, and are directed downwards and forwards, and slightly inwards. The other two lateral planes of the out- let are formed by the descending rami of the pubic bones, and the ascending rami of the ischia; they extend from the middle of the arch of the pubes to the tuberosities of the ischia, their direction being upwards, forwards, and inwards. If we considered the bony pelvis as a complete canal, it would be pinched inwards at the points of the ischial spines and tuberosi- ties of the ischia, and bulged outwards at the sites of the great sacro-sciatic foramina. These circumstances, together with the shallowness of the anterior or pubic portion, contribute to alter the diameters of the superior, middle, and inferior planes. The key to the pelvic mechanism, in an obstetric sense, may be said ,, to be the spinous processes of the ischia. Here it is that the foetal head makes its most decided change of position. The changes of position and direction which bring the foetal head to occupy, at the outlet of the pelvis, the right oblique position as the most common presentation, are effected mainly by the ana- tomical adaptations of the pelvis, aided by the mechanism of the foetus, and the position of the rectum in the notch by the side of the sacrum on the left side. (Fig. 92.) The normal depth of the female pelvis, is, according to Burns, as follows : From the promontory of the sacrum to the tip of • CHARACTER OF DEEP AND SHALLOW PELVES. 307 coccyx, from 5 to 6 inches; from the brim to the tuberosity of the ischium, 3.75 inches; anteriorly, from 1.5 to 2 inches. The variations which obtain in this respect exercise a considerable influence upon the progress of labor. Deep pelves are often somewhat funnel-shaped, and shallow pelves are not merely wide in appearance, but wide in relation to the size of the body. If a pelvis be very much shallower than usual, the points of resistance to the passage of the fcetal head are of course dimin- ished in number, and the track of the foetus is materially short- ened also: labor, under these conditions, is unusually rapid, unless there is coexistent distortion. It is .well to bear in mind, that the shortest pelvic diameter is that between the two ischial spines (3.5 inches) and the longest is an oblique diameter, ex- tending between the sacro-iliac synchondrosis of either side to the tuberosity of the ischium opposite. This line is six inches Fig. 92. Side view of the pelvis. in length, and corresponds very nearly in position with the long axis of the foetal head in an Ordinary occipito-anterior presenta- tion, when the head is fairly lodged in the cavity of the pelvis. With regard to the External Measurements of the pelvis, it may be stated that the same method of ascertaining the antero- posterior, lateral, and oblique diameters, which helps us so much to understand the cavity, will assist us in understanding them. The antero-posterior diameter of the pelvis, externally, is about eight inches; the external transverse—i.e., from crest to crest of the ilia—about 14 inches; the oblique i.e., from the antero- 308 EXTERNAL MEASUREMENTS OF THE PELVIS. superior spine of one ilium to the postero-superior of the other— about eight inches. These diameters are all in the same plane. There are other diameters in various planes, a knowledge of which is useful. For instance, from the spine of the last lumbar vertebra to the antero-superior spine of either ilium, 6 inches 7 or 8 lines; from the symphisis pubis to the infero-anterior spinous process, about 4 inches; from the tuberosity of either ischium to the postero-superior spine of the ilium of the opposite side, 6 inches 6 lines; from the great trochanter of either side to the postero-superior spine of the ilium of the opposite side, about 8 inches. These measurements are valuable, not because we can determine from them the internal pelvic diameters, but because, unless the proportionate dimensions stated above are maintained, there must necessarily be an alteration in the size of the pelvis, or serious distortion. When speaking of deformed pelves, it will be pointed out how the diminution of each of these diameters is indicative of certain mal-relations between the pelvic bones. LECTURE XX. THE ANATOMY OF THE FCETAL HEAD. Gentlemen :—The anatomy of the foetal head, and the anatomy of the pelvis, are the elements of obstetric mechanics; and the behavior of the former in the cavity of the latter will, of course, depend upon the mutual relations of each. It is to the cranium of the foetus, however, that our attention is now directed. Speaking, in general terms, the head of the fully de- veloped foetus is au irregular ovoid mass of very various diame- ters, and various compressibility, according to the diameters in which the compressing force is applied. It is attached to the neck in such a manner as to project posteriorly more than anteriorly; and it rotates upon this point of attachment to the extent of a quarter turn without any harm accruing to the infant. The bones of the head may be arranged into two systems : one, the bones of the cranium; and the other, those which compose the face and base of the skull. The bones of the face and.base of the skull differ from those of the calvarium in being far more highly ossified; they are, in fact, so advanced in development as to be practically unyielding; and the adaptations, therefore, which exist between the configuration of this part of the foetus and the maternal skeleton are obtained either by the slight compressibility of the soft parts of the foetal face, or by special morphological conditions of the bones themselves. The bones of the face and base of the skull are early developed, and un- yielding in their texture, in order to protect the delicate organs of special sensation and important ganglia at the base of the brain from the injurious effects of mechanical violence during labor. The hemispheres of the brain perform functions the integrity of which is less necessary to life, require no such pro- tection, and submit to considerable compression within their movable case. It is interesting to remark, that the immovable 310 ANATOMY OF THE FCETAL HEAD. portion of the bones of the head occupies such a position that a moderate force of compression applied to the opposite aspect of the cranium tends rather to increase than to diminish its capa- city ; according to the well-known law which provides that a soherical vessel contains greater bulk in proportion to its super- ficies than any other form or receptacle. The lower jaw in the foetus is widely different from an adult maxilla, as may be seen by reference to the accompanying engraving; the ramus is short and oblique, and the empty alveoli of each jaw are thus per- Fra. 93 s 1, 2. Occipitofrontal diameter. 8, 4. Occipito-mental. 5, 6. Cervico-bregmatic. 7, 8. Fronto-mental. mitted to come into actual contact, whilst the body of the bone is shallow; and thus by a combination of provisions, the fronto- mental diameter is kept within convenient limits. Were the chin pronounced, and the fronto-mental diameter consequently much increased, it would, in ordinary presentations, almost inevi- tably strike against the right side of the promontory of the sacrum, and prove an insuperable obstacle to the movement of rotation taken by the head in its descent through the pelvis. The diameters of the facial portion of the head are its smallest diameters, and adapt themselves to the smallest diameters of the pelvis. Thus the bi-temporal diameter, which is variable to a very slight extent, is little more than two inches and a half, the bi-malar diameter is barely three inches, and the bi-mastoid is not much over two inches. These diameters all pass through the cavity of the pelvis, between the spines of the ischia, in ordinary occipitoanterior presentations, as well as in those cases where the occipito-posterior presentations have passed into the former. The unyielding portion of the head might be represented by an MEASUREMENTS OF THE FCETAL HEAD. 311 oval plane, having one end at the back of the neck, and the other somewhat above the brow, whilst its conjugate diameter would nearly correspond with a line passing through the skull from ear to ear. It is evident that whatever error an obstet- rician might fall into as regards the actual position of the head, from failing to take into account the moulding the calvarium undergoes in transitu, none can arise from this source as far as the face and ears are concerned. In cases of distortion or con- traction, then, it follows that a recognized ear, or cheek-bone will be a better index to the actual position of the head than any point in its more movable part. Dr. Hamilton was of opinion that the compression of the cerebral hemispheres during labor produced a paralyzing effect upon the limbs of the foetus, and tended to keep them motionless under the action of the uterus—an opinion shared in by Dr. Ramsbotham. That part of the head which is called the skullcap consists of the occiput, the parietal bones, and the frontal bones; the temporal bones scarcely require to be noticed. * In the vast majority of cases, these bones are soft and semi-cartilaginous, and connected to each other only by the dura mater and scalp ; their contiguous edges are bevelled off, and they may be made to overlap each other to a very considerable extent. Between the edges of contiguous bones are grooves called sutures / and where three or more sutures meet, there is a deficiency of bone, \s called a fontanelle. The arrangements for solidity in the face and base of the skull are not more conspicuous than the pro- visions made for plasticity here ; in whatever direction compres- sion is applied, it results in a modification of the contour of the head, partly because the bones bend, and partly because they overlap in various directions. As a general rule, it may be laid down, that in ordinary presentations the longer the head remains in the pelvis, the more ovoid will it become, always provided that the pelvis is not absolutely deformed. There is a considerable discrepancy between the estimates of dimensions given by various writers. Dr. Meigs is very positive in affirm- ing that the estimate usually given of the occipito-frontal and occipito- mental diameters is far too low. It is not unlikely that much may depend upon the period when the measurements are taken, for certainly the cranium of a foetus, immediately after what is vulgarly called a " hard labor," is materially longer 312 MEASUREMENTS AND SUTURES. than twenty-four hours later, and, it may be presumed, than before it has been subjected to the modelling process by which it attains its adaptation to the maternal passages. Confining ourselves, however, to average figures, which shall represent rather the relative diameters of the foetal head, than an exact estimate of each individual measurement, the following table may be relied upon as sufficiently accurate for all practical pur- poses. The really important consideration is not the absolute, but the relative, admeasurements of the skull; we are utterly unable, in any given case, to determine the magnitude of the body about to pass, and are therefore compelled to frame our mechanical appliances upon considerations of proportion. 1. The occipito-frontal diameter 4.5 inches to 4.75 2. The occipito-mental .... 5.0 " " 5.25 3. The trachelo-bregmatic . . . 3.75 " 4. The sub-occipito-bregmatic 3.25 " 5. The transverse or bi-parietal 3.5 " 6,. The trachelo-frontal .... 3.25 " It will be observed that the two first of these measurements are particularly noticed as varying, and they do, in fact, vary as labor advances, being the direction in which the greatest range of alteration is admissible. The circumference of the head varies, of course, according to the direction in which it is taken. Thus the ordinary presenting circumference, which passes under the occiput, and round the parietal bones, to a little behind the bregma, is about 11.5 inches, and the occipito-frontal is rather more than 14 inches, and the occipito-mental is nearly sixteen inches. It is unnecessary to burden the memory with any fur- ther details on this head. The sntnres with which we are mainly concerned are the coronal, the sagittal, and the iambdoidal; the temporal sutures between the temporal bones and the inferior concave border of the parietal bones are comparatively uninteresting, because the ear is quite as easy, if not easier, to recognize in all cases where it is desirable to know the position of that part of the head. The coronal suture—so called because the ancients wore their tri- umphal crowns in that position—is the line of demarcation between the frontal and parietal bones; it extends transversely, and almost vertically, over the head, from the summit of the squamous portion of the temporal bone on one side, to a corres- SUTURES AND FONTANELLES. 313 Donding point on the other side ; its line is broken by the great or anterior fontanelle. The sagittal suture projects directly back- wards from the coronal in the middle line, and lies between the opposed superior borders of the two parietal bones; posteri- orly it abuts upon the apex of the lambdoidal suture. The lamb- doidal suture—so called from its resemblance to a Greek A—is formed by the opposed borders of the occipital and parietal bones : if two parietal bones are placed in situ, it will be seen that, owing to the obliquity of their posterior borders, an angu- lar recess is formed where they meet; into this recess the occipi- tal angle fits, and just between the superior angle of the bone and the angular recess alluded to, is the small or posterior fon- tanelle. There is a suture between the two divisions of the frontal bone which varies in width, but is always recognizable where it abuts upon the great fontanelle; the sagittal, coronal, and lambdoidal, are however the important sutures, and of these the sagittal is paramount. The f ontanelles are spaces between some of the cranial bones, into which the sutures debouch. British obstetricians gene- rally take cognizance only of two; an anterior or greater, and a posterior or lesser. Continental writers speak of two others— the temporal; but as the finger could hardly impinge upon them unless the orbit were within reach also, it appears unwise to Fig. 94 Anterior and posterior fontanelles. divert attention from the more to the less valuable aid to diag- nosis. The anterior or greater fontanelle, or bregma, is a rhom- 314 CHARACTERISTICS OF THE SUTURES AND FONTANELLES. boidal space into which two fingers may be easily laid ; its long diameter is from before backwards, and the greater half of the rhomboid is in front of its lateral angles. The sagittal suture joins its posterior angle, the inter-frontal enters its anterior angle, and the two halves of the coronal suture debouch into its lateral angles. The posterior or lesser fontanelle is small and triangular; it receives the sagittal suture into its anterior angle, and the two limbs of the lambdoidal suture into its lateral angles. The posterior fontanelle is the one with which it is most neces- sary to be familiar. However easy it may seem at first sight to determine which suture or which fontanelle is touched in any given examination, beginners are very often mistaken, and there are some circum- stances which may embarrass others than tyros. It may be as well to point out a few distinctions between each suture and each fontanelle. The sagittal suture may be recognized by its debouch- ing into two fontanelles ; the coronal by its joining a large fon- tanelle at one end, and leading to a more unyielding part of the cranium at the other; the lambdoidal byT its joining only a small fontanelle. The anterior and posterior fontanelle, if they should happen to approximate in size to each other, may yet be distin- guished by the anterior having four angles, and its four sides bounded by bony margins, which do not project into the space; while the posterior has but three angles, and the bones around it are the three acute apices of the occipital and two parietal bones. There is occasionally a false fontanelle in the course of the sagittal suture, the result of defective ossification in the opposed edges of the two parietal bones ; if it is borne in mind, however, that only two lines of suture can be traced from such a space, it cannot be a source of any great difficulty. Before the membranes are ruptured, it maybe somewhat difficult, when they are tough, to appreciate all the points of difference between the sutures and fontanelles ; sometimes ossification is so abnormally advanced or delayed as in a measure to destroy the characteristics of the fon- tanelles ; and when the bones of the head overlap each other very much during its passage through the pelvis, it may be a matter of great difficulty to recognize anything very distinctly. The greatest difficulty in the way of accurate diagnosis is pre- sented perhaps in those cases in which the membranes have been ruptured early, and the head has been long in the pelvis tio-htly DIVERSITY IN SIZE OF MALE AND FEMALE FCETAL HEADS- 315 girt by a rigid cervix uteri. Under these cirumstances, the scalp becomes swollen, puffy, and infiltrated with serum and some- times blood, and nothing can be felt distinctly through it; it may be almost impossible to pass the finger beyond the puffy tumor, so as to reach a part of the head covered by natural scalp, and such cases have been mistaken ere now for breech presenta- tions. Fig. 95. Bi-parietal diameter; sagittal and lambdoidal sutures with posterior fontanelle. There are some general considerations connected with the size of the foetal head which are worthy of attention. In the first place, it must be remembered that the average dimensions of the male foetal head are considerably greater than those of the female; the excess in the circumference which most commonly presents is about half an inch, and this is quite sufficient to make a serious difference both in the chances of danger accruing to the infant and the mother. The question of safety to mother and child is very much a matter of time; whether the delay results from rigidity of the passages as in primiparae, or from greater size of the head as when the foetus is masculine, the result is pretty nearly the same. The late Dr. Joseph Clarke, of Dublin, a very distinguished accoucheur, investigated very minutely the ques- tion of the difference of the size of the brain of the two sexes at the time of birth. He ascertained by the admeasurement of a large number of cases, that the circumference of the male head is greater by half an inch, or about the twenty-eighth part of the entire circumference, than the female head, at the time of birth. The fact that the male foetal head is actually larger than the female having once been established, all the disastrous conse- quences of which Prof. Simpson has given statistical proof 316 PARTURIENT ACCIDENTS WITH MALE CHILDREN. follow as inevitable. In cases of tedious labor-convulsions, puer- peral convulsions, puerperal fever, ruptured uterus, haemorrhage, and instrumental delivery, by far the greater number of children are males. In cases of pelvic abscesses, ruptured perinaeum, and vesico-vaginal fistula, the same undesirable preeminence attaches. to male children. The following are the principal conclusions of Prof. Simpson : 1. Of the mothers that die under parturition and its immediate consequences, a much greater portion have given birth to male than to female children. 2. Of still-born children, a larger proportion are male than female. 3. Of children born alive, more males than females suffer from the morbid states and injuries which result from parturition. 4. More males than females die in the early period of infancy, and the disproportion diminishes from birth to some time after- wards. 5. More dangers occur, both to mother and infant, in first than in subsequent labors. 6. Of children which die in utero before labor as many are females as males. 7. Of the accidents which happen after the birth of the foetus itself, as many occur with female as with male children. There are other aphorisms on this question, laid down by the same authority, but they are only corollaries of the foregoing propositions, and need not, therefore, be stated. Besides the effect of sex in modifying the size of the foetal head and increasing the pain and danger of parturition to the mother and child, we have to consider the effects of race and civilization upon the head of the foetus at the time of birth. All enthologi- cal researches tend to show, that, with the advance of civilization, the human head has increased in size. The oldest crania in existence, much older than the mummies of Egypt, are the skulls found in various parts of the world in diluvial caves, with the fossil remains of extinct animals. These skulls apparently belong to other races than those which now inhabit the countries in which they are found ; they have a small development of the brain, and resemble the skull of the Carib in flatness of the fron- tal bone. The heads of Peruvian and Egyptian mummies are considerably below the size of the European cranium. Nothing DIFFICULTIES WITH THE CIVILIZED AND SAVAGE RACES. 317 within the range of human anatomy stands in a stronger con- trast than the cerebral size and development of the New Hol- lander, or the Bushman, and the Caucasian races. The different condition of education amongst different classes of the same race also has its effect on the size of the brain and cranium. Hatters state that the size of the head is greater in the same classes in towns, than in agricultural districts, in the educated than the uneducated. Tiedemann gives from 31bs. 2oz. to 41bs. 6oz. troy weight, as the average weight of the adult male European brain; but he found that of Cuvier weighed upwards of 41bs. lloz., and that of Dupuytren 41bs. lOoz. [Authorities differ in respect to the weight of the brain of various distinguished persons. The following is extracted from the post mortem of Daniel Webster in the American Journal of Medical Science, which will give an idea of their relative size: Cuvier, 41bs. 5drs. lOgrs.; Webster, 31bs. 15oz. 12drs.; Dupuytren, 3lbs. lOdrs. 27grs.—avoirdupois.] The same authority gives the average weight of the female brain as from 4 to 8oz. less than the male; and he found the different size of the male and female brain was perceptible at birth, in this according with the views of Dr. Joseph Clarke and Dr. Simpson. The increase is not confined to the head alone. Dr. Clarke found that, on the aver- age, taking the whole body, males weigh 9oz., or nearly one- twelfth of the entire wreight more than females. It seems a clear inference, that the brain and head of the uncivilized and the uneducated must be, on the average, smaller than those of the educated and civilized ; and we have seen in the comparison of the male and female head at the time of birth, how small a difference in the size of the fcetal head is sufficient to increase the dangers and, necessarily, the sufferings of parturition. Dr. Simpson is of opinion that the comparative difficulty of par- turition with male and female children extends to the foetus of civilized races, and he refers the increased suffering of the civi- lized woman in childbirth to the size of the foetal head. Some writers have expressed the opinion, that savage women do suffer as much or nearly so, as the women of civilized races. [Dr. Livingston, in his recent researches in S. Africa, says negro women generally suffer less than Europeans, principally, as it appears, because they consider parturition to be an act of nature, and less a disease than do the latter.] 318 CIVILIZATION AFFECTING THE SIZE OF THE FCETAL HEAD. But the general bearing of all the knowledge we possess on this subject, supports the view, that barbarian women suffer far less than women in a state of civilizaticn. The size of the fcetal head must be considered the most important element in this matter, though at the same time, there is the greatest sensibility induced by the habits and social condition of the civilized and highly cultivated female to be taken into account. Civilization not only influences the size, but the relative size of the different, parts of the fcetal head. In uncivilized races the tendency is to increase the occipito-mental diameter, by the protuberance of the occiput, and the greater development of the lower part of the face, and to diminish the occipito-frontal diameter by the flattening of the frontal bone and the low development of the anterior cerebral lobes. The diminution of this diameter must lessen the difficulty in the passage of the fcetal head. In the case of a negress, whose labor I had the opportunity of witnessing, the great mass of the fcetal brain was behind the auditory foramen, the fcetal head having the shape represented in Fig. 96. Other influences, besides civilization and education, have an influence upon the size of the head. The Caribs flattened the foreheads of their children, and the continuance of this practice through succeeding generations produced a natural flattening of the anterior part of the head, until the Carib infants were born with flat heads. The practice of flattening the head prevailed in Mexico, and, at an early date, in the eastern parts of Europe. Hippocrates gives an account of the Macrocephali, a Scythian race believed to have inhabited the Crimea, of whom the Father of Physic says: " There is no other race of men which have their heads in the least resembling theirs. At first, usage was the principal cause of the length of their head, but now nature cooperates with usage. They think those the most noble who have the longest heads. It is thus with regard to the usage: immediately after the child is born, and while its head is still tender, they fashion the head with their hands, and constrain it to assume a lengthened shape, by applying bandages and other suitable contrivances, whereby the spherical form of the head is destroyed, and it is made to increase in length. Thus at first usage operated, so that this constitution was the result of force • but in the course of time it was formed naturally, so that usage CIVILIZED BARBARITY. 319 had nothing to do with it." Mr. Adams, the learned translator of Hippocrates, cites some researches of Dr. Rathke, as afford- ing a remarkable corroboration of the preceding observations. Certain tumuli have been excavated in recent years at Kertch, and there were found in them several skeletons, in which the form of the head was greatly elongated, so as to resemble the shape described by Hippocrates in the Macrocephali. It has been suggested that one object had in view by the races accus- tomed to flatten the head was, that of producing a shape favor- able to easy parturition. Binding the heads of children upon a board is practised in some parts of Europe at the present day. I have seen Polish infants arranged in this manner apparently as a mere fashion or habit. The round head of the Greek and Turk are believed to have been in part produced by the effect of the national cap and turban, continued through successive centuries. [" As we went round the long galleries (of the Royal Lunatic Hospital at Charenton, France), Dr. Foville pointed out to us several persons whose heads were of a very peculiar form, more or less perfectly approaching the pyramidal; the face might re- present the base and the occiput the apex. Their foreheads were peculiarly flat and narrow. In reference to them he remarked, that this species of head was peculiar to a particular department of France, in the same manner a3 the Flat-head Indians are peculiar to one tribe. In this district more children die at an early age than in any other ; the diseases bring principally con- vulsions and other maladies, which depend upon the health of the brain. More insane come from this than from any other quarter of the kingdom, in proportion to the population; and finally more cases of idiocy, epilepsy and the like than elsewhere. What is the cause ? Evidently the peculiar shape of the head, which pervades the people of that whole region, who all partici- pate in this deformity, in a greater or less degree, without a single exception. So universal is it, indeed, that some painters and sculptors regarding it as the natural head of man, have drawn from this source their beau-ideal of beauty; and fixed upon the sloping shoulders of their Yenuses and Apollos, heads gracefully rising in tapering pyramids. An investigation of this extraordinary phenomenon has been made, and the cause discovered, the Flat-head Indians are 320 DEFORMITY OF FCETAL HEAD. known to alter the form of their infants' heads by pressure on the skull, when its bones are in a more or less cartilaginous state and not yet firmly united. From this fact it was suspected that some such prank was practised on these children of France, and sure enough, it has been found* that mothers and nurses have been employed for centuries in the wholesale business of driving mad, maiming, and murdering the children of a parti- cular district. This enormity has been committed by putting a peculiar cap upon the heads of their offspring, and fastening it tightly there by means of a strong band; and this simple cord has killed its hundreds and diseased an entire region! With the Flat-head Indians the pressure is in another direction, and may affect the intellect while the nutritive organs are unimpaired. Dr. Foville mentions an autopsy made upon one of their country- women, who had the venous circulation so impeded that a large plexus was formed, for the accommodation of which a deep cavity was sunk in one of the lobes of the brain.," etc.—G.—Old Wine in New Bottles • or, the Spare Hours of a Student in Paris. New York, 1849.] Fia 96. Skull of a Negro Foetus. LECTURE XXI. THE MECHANISM OF LABOR. Movements of the Fatal Head during its Passage through the Pdvis: Obliquity—Flexion—Rotation—Extension—Restitution. Gentlemen :—Great improvements in any department are commonly of slow growth. This may be said emphatically of our knowledge of the Mechanism of Labor, which with the motor forces engaged in parturition, stand at the very founda- tions of the science and art of Obstetrics. More than a cen- tury ago, to the honor of the Dublin school of midwifery be it said, Sir Fielding Oulde called in question the opinion which had previously prevailed universally, that the head entered and passed through the pelvis in the direction in which it emerges— namely, the antero-posterior diameter. In his little work, published in 1741, he taught that the face of the child did not lie upon the sacrum of the mother, but was always, in natural cases, turned to one side or the other. He believed, however, that the chin of the child was turned towards one of the shoul- ders, the neck of the foetus being partly rotated upon its body. This error respecting the different position of the foetal head and trunk, was corrected by Smellie, and the belief in the oblique position of the head in the pelvis gained ground amongst accou- cheurs in different countries. In 1771, Saxtorph, of Cophen- hagen, and Solayres de Renhac, of Montpellier, published almost simultaneously the discovery that the head not only enters the pelvis with the long diameter in one of the oblique diame- ters of the pelvis, but that the long axis of "the head, in the great majority of cases, occupied the right oblique diameter; the occiput being directed towards the left foramen ovale, and the forehead towards the right sacro-iliac symphisis. Solayres de Renhac went, however, beyond his contemporary, Saxtorph, in describing the mode in which the head passed through the out- let under various circumstances, to which we shall have here- after to revert. These advances were realized by practical 322 naegele's INFLUENCE UPON MIDWIFERY. accoucheurs, especially by Baudelocque and his disciples; but it was not until 1818 that Naegele" gave a full account of the behavior of the head in the pelvis under the various circum- stances under which it may be placed in natural labor. Discard- ing all theory, and looking closely to the operations of Nature, he obtained an amount of knowledge which enabled him to systematize the facts of previous authors, and give us an account of the mechanism of labor, which subsequent observations have all tended to confirm. No other work, of equally small size, ever exerted greater influence upon any branch of medicine than that of Naegele upon midwifery. It may be termed, indeed, the Euclid of Obstetrics, but it will not have executed its mission until every accoucheur, in each individual case coming before him, entirely masters the position of the foetal head. Nothing less than this should be aimed at by every obstetric practitioner. We must not be content with knowing that the head presents, but we must know the exact mode and direction in which the head passes through the pelvis; otherwise we scarcely attain beyond the knowledge of the midwife. " Judgment," to use the words of Hippocrates, can never be otherwise than " diffi- cult," in this subject. In estimating relations of position, we always naturally refer to the position of our own body as the standard of comparison. But in case of labor, the accoucheur stands in the upright position, and has to deal with the mother and the child in the horizontal position ; the foetus and the mother being themselves reversed, the child standing, as it were, on its head within the system of the mother. These complicated positions are so difficult to master, that I have heard men who have attended thousands of cases, confess themselves as only beginning to be certain of the presentations in particular instances. It is only by a careful study of the pelvis and the fcetal head in the dried state, and a pains-taking observation of the relations of -the head and the pelvis in every case of labor, that will enable you to master this difficult problem. Naegele tells us that he kept his finger on the head during the whole course of labor, when he wished to ascertain any particular point. There is still enough to be made out respecting the func- tion of parturition to reward every diligent student who may devote his energies to the prosecution of this subject. In every direction we must analyze and synthesize the movements of the MECHANISM OF LABOR. qr>9 foetal head, and the motor forces and the mechanisms which urge and direct it in its course through the pelvis and parturient canal. The largest movement of the foetal head in parturition is that through the canal of the pelvis, and the passage formed by the vagina and soft parts. This movement is common to all the positions in which the head passes through the pelvis. In its performance, the centre of the head corresponds pretty nearly with the axes of the hard and soft portions of the parturient canal. To this common movement are superadded various movements of the head upon its bilateral axis, its antero-poste- rior axis, and its vertical axis, all of which vary in character and extent according to the position in which the head first engages in the pelvis. These movements and differences, considered in relation with the pelvis, constitute the mechanism of labor and the several " positions " as they are called, in which the head presents and passes through the pelvis and soft parts. The head lies at very various depths at the commencement of labor. Sometimes the developed cervical portion of the uterus, and the contained foetal head, lie entirely in the pelvis, before the com- mencement of any uterine action. At others the head is high up in the pelvis, and has scarcely, if at all, entered the brim. As Dr. Rigby points out, the head is more frequently low in the pelvis in primipara, and high up in multiparous women. The cause of this is probably the greater rigidity of the abdominal walls in primiparae as compared with multipara. In many mul- tiparous cases, the head is, however, wholly within the pelvis for sometime before the commencement of labor. For the descrip- tion of labor it is convenient to take those cases in which the head is high up as the standard, this gives us an opportunity of tracing the steps by which the head descends through the pelvic canal. The mechanism of labor is necessarily somewhat compli- cated, and it should be the aim of all teachers to render it sim- ple as possible, by describing as few varities as may be consis- tent with nature, and requisite to be understood in practice. It is easy to multiply varieties in the position of the head, by insisting upon trivial differences ; but dis-service rather than service is done in this way to the advance of obstetric know- ledge. It is to be hoped that each successive describer of the 324 FOUR POSITIONS OF HEAD PRESENTATION. process, having the aid of those who have gone over the same subject before him, may do something towards rendering the steps of this progress more and more intelligible, and more deci- dedly linked with practice. There are four principal positions in which the fcetal head presents in the pelvis, and these posi- tions we shall now proceed to consider. The two first positions are termed Occipito-Anterior, because in them the occiput is placed towards the pubis. The other two are called Occipito- Posterior, because in them the occiput is turned towards the sacrum. In the First Position, the head, as already mentioned, enters the pelvis in the right oblique diameter, or in a line between the transverse and oblique diameters. The occiput is placed towards the left acetabulum, and the forehead towards the right sacro-iliac sjmchondrosis. At first, the long diameter of the head is parallel, or nearly so, with the superior plane of the pelvis, the occiput and sinciput being about on the same level. There is, however, a considerable lateral obliquity of the head. The right side of the cranium is considerably lower than the left, so that the most depending part of the cranial sur- face is the protuberance of the right parietal bone. As the head descends, there is a slight rotation upon the bilateral axis, and the occiput generally becomes lower in the pelvis than the fore- head. This descent of the occiput is called the Flexion of the Head. Fig. 97. Brim of the Pelvis and Base of the Foetal Cranium in the First Division. The above engraving shows the entrance of the fcetal head into the pelvis in the right oblique diameter after it has com- MECHANISM OF THE FIRST POSITION. o2o menced its descent. The mastoid process of the left temporal bone and the chin are at this time the highest portions of the foetal head ; the right half of the occipital bone, and the adjoin- ing portion of the temporal bone, being depressed. If we examine per vaginam when the head is in the upper part of the pelvis in this position, the right tuber parietaleisfelt through the walls of the anterior portion of the cervix uteri. This is the point with which the finger comes in contact at the most depending part of the head. The right ear of the child can be felt behind the pubes, if the os uteri is sufficiently open to allow of its being reached. At this time the os uteri does not occupy the axis of the pelvic canal, but is more posterior and directed towards the upper part of the sacrum. If the finger is passed into the os uteri, the sagittal suture is felt crossing the field of the os, in an oblique direction. The patient lying on the left side, the accoucheur standing or sitting behind, and bending over her to make the examination, feels the sagittal suture run- ning forwards and downwards in one direction, and upwards and backwards in the other. The sagittal suture divides the os uteri unequally, a larger portion of the middle and upper part of the right than the left parietal bone being included within the ring of the os. It is this middle and upper portion of the right parietal bone which is felt in making an examination at this period, and it is here that the tumor of the scalp is formed, when this arises from the pressure of the head against the partially dilated os uteri. If the os uteri is sufficiently dilated to allow the finger to be passed along the sagittal suture, it reaches in front, and to the left side of the mother, the triangular posterior fontanelle, and the diverging lambdoidal suture, while behind and to the right side of the mother, it comes in contact with the lozenge-shaped anterior fontanelle, and the coronal and frontal sutures. The earlier the examination is made, the more deci- dedly oblique, or approaching the transverse direction, will the sagittal suture be found. While the foetal head is passing through the brim of the pel- vis so as to enter the pelvic cavity, it has been shown to occupy the right oblique diameter. It has already been mentioned, that the first movement of the head consists of a partial revolu- tion upon its occipito-frontal axis, so as to effect the depression of the right parietal bone. This movement is termed the 326 WHEN THE CAPUT SUCCEDANEUM 18 FORMED. Obliquity of the Head. In the next movement the foetal cranium oscillates to a slight extent upon its bi-lateral axis, so as to cause a dip of the vertex. This movement which brings the chin into contact with the sternum, is called the Flexion of the Fcetal Head. The lateral obliquity, the dip of the occipital bone, and the position of the long diameter of the fcetal head in the right oblique diam- eter of the pelvis in the First Position, are shown in Fig. 97. As the fcetal head descends in the pelvis, it performs what is termed,par excellence, its "Rotation." The long diameter of the head changes from the oblique to the antero-posterior diameter, or nearly so. The most prominent portion of the occipital bone glides downwards and forwards upon the inclined planes formed by the descending ramus of the pubis and the internal surface of the ilium, so that the middle portion of the superior and posterior quarter of the right parietal bone, and its posterior and upper angle, become successively the most promi- nent points of the descending head. It is in this latter position the tumor of the scalp or caput succedaneum is formed, by the pressure of the soft parts of the outlet upon the head. In this position, also, the head emerges underneath the arch of the pubis. In the rotatory movement from the oblique to the an- tero-posterior diameter, the head describes about one eighth of the circle. In emerging from the pelvis, the head is placed almost as obliquely as at its entrance, the right tuber parietale being still lower than the left. The head does not emerge either with the occipital or parietal protuberance foremost, the part which escapes first being a point between the two, namely (as already mentioned), the upper and posterior part of the right parietal bone. The following engraving represents the foetal head low down in the pelvis, in the first position. The pelvis is placed upon its left side, so as to imitate as far as possible a resemblance of what is felt by the finger of the accoucheur, in making an examination at this part of the process, as far as the bones are concerned. [The young reader who has probably been taught to practise the toucher with the woman on her back in confinement as now taught in most of the American schools, may reverse this and fol- lowing similarly placed cuts, noting that P indicates the pubis under which the occiput presents.] I believe this is the first time such a representation has been RE-ROTATION OF THE HEAD. 327 made, and it appears to me to convey more information than any figure of the base of the fcetal skull and brim of the pelvis —the method hitherto followed in illustrating the mechanism of labor. Fig. 98. Outlet of the pelvis, and the Foetal Head passing through it in the First Position. The asterisk marks the presenting portion.—P, the Pubis. Another movement of the foetal head now demands our atten- tion. We have referred to the flexion of the head, by which the chin is brought towards the sternum, and the occiput depressed. When the occiput has passed under the arch of the pubis, this portion of the head becomes to a great extent a fixed point, and the frontal bone and face of the child come down, describing an arc in their progress. This is called the Extension of the Head, the chin being now separated from the sternum, and the forehead appearing at the lowest part of the cranium. Immediately after its emergence from beneath the pubic arch, the head usually rotates back again to the aspect it held in the upper part of the pelvis, the face being now turned towards the right thigh of the mother. This re-rotation, which is termed the Restitution of the Head, is effected in the following manner: It generally happens, that as the head escapes, the right shoul- der of the foetus is lowest in the pelvis, and impinges upon the 328 CONCLUSION OF THE FIRST POSITION. anterior surface of the right ischial spine. From this point it rotates forwards towards the arch of the pubis under which it passes out, the left shoulder resting upon the perinaeum, and generally escaping first. Thus the body of the foetus rotates in an exactly opposite direction to the previous rotation of the head. The left side of the head glides down the left ischial plane, and the right shoulder glides down the plane of the right ischium. Fig. 99. If it should happen, which is occasionally the case, that the left shoulder be lowest in the pelvis, it glides down the left ischial plane, the shoulders rotate in the same direction as the head, and the face of the child is then turned downwards and towards the left thigh of the mother. When the pelvis is large and the delivery effected suddenly, the shoulders are sometimes expelled in the transverse diameter of the pelvic outlet without any rotation. In the emergence of the head and trunk from beneath the pubis, the direction impressed by the perinaeum, and the expulsive efforts is such that the head turns upwards between the thighs of the mother, in front of the symphisis pubis, as represented in the preceding engraving. In the Second Position, the occiput is turned towards the right acetabulum, and the forehead towards the left sacro-iliac synchondrosis, as the head passes through the brim. The left THE SECOND POSITION OF THE HEAD. 329 part of the base of the skull is lowest, the occipital dip, or flexion, being the same as in the first position. The left side of the head is the lowest, in the second position, as the head descends, the same portions of the left parietal bone being prominent, instead of the right. The left ear is felt behind the pubis. The sagittal suture is now found nearly parallel to the left oblique diameter. In an examination, the finger passes upwards and forwards to reach the posterior fontanelle, and downwards and backwards to reach the anterior. The occiput glides down the right ischial planes. The rotation is precisely Fig 100. the same as in the first position, except that it is in the reverse direction. The rotatory movements of the shoulders are also reversed, the face of the child generally turning downwards, and to the left thigh of the mother. Figure 101, page 319, repre- sents the head passing through the pelvis in the second position. Let us now proceed to recapitulate the different evolutions per- formed by the foetal head in its passage from the pelvic brim to the external world in the first and second positions. I.—The movement in the parabolic curve formed by the axis of the pelvic canal and of the vagina. The different parts of the foetal head change their position in this progress, but the centre of the foetal head may be con- sidered as traversing the axis of the pelvis and of the soft parts of the parturient canal. II.—The movement of the fcetal head upon its occipito-frontal axis. 330 ROTATION OF THE HEAD IN THE PELVIS. This movement causes one side of the fcetal head to become lower than the other during the whole progress of labor after the head has entered the brim. Fifr. 101. Outlet of the Pelvis, and the Foetal Head passing through it in the second position. The asterisk marks the presenting portion.—P, the Pubis. III.—The movements of the fcetal head upon its bi-parietal axis. These movements consist—first, of the depression of the occiput, and second, of the depression of the sinciput. In the descent of the head through the pelvis, the occipital pole is depressed, but as it emerges under the pubic arch, the frontal pole becomes the lowrest point. This oscillation of the forehead downwards upon the bi-lateral axis, constitutes what is termed the extension of the head. IY.—The rotatory movements of the foetal head upon its per- pendicular axis. These movements constitute the rotation of the head in the pelvis, and subsequent to the delivery of the head, the latter movements being called the restitution of the head. If the head should be placed transversely at the brim of the pelvis, since it emerges in the antero-posterior diameter nearly so, it makes about one-fourth of a complete rotation, but if it be placed in MECHANISM OF THE THIRD POSITION. 331 * the oblique diameter at the commencement of labor, the rotation is only one-eighth of a circle. In the Third Position, the forehead is, at the commence- ment of the passage through the pelvis, placed opposite the left acetabulum, and the vertex towards the right sacro-iliac synchon- drosis. The fcetal head occupies the right oblique diameter, as in the first position, only the long diameter of the head is exactly reversed, the sinciput being directed forwards, and the occiput backwards. Fig. 102. Brim of the Pelvis, and Base of the Cranium in the Third Position. The anterior and posterior fontanelles are at this time gene- rally on a level, or nearly so. The saggital suture, as the patient lies on the left side, runs obliquely forwards and downwards, and upwards and backwards, just as in the first position. Passed downwards and forwards, the finger comes to the anterior fontanelle, and upwards and backwards it reaches the posterior bregma. Instead of the right tuber parietale, it is the left parietal bone which is felt lowest in the pelvis. Generally in these cases, as labor proceeds, the vertex descends more than the forehead, so that it is easier to reach the posterior than the anterior fontanelle. When the head is thus placed in the third position, it may take two paths in its exit from the pelvis. In one, the vertex may continue to descend, and approach towards the antero-posterior diameter of the outlet, the head being expelled with the forehead towards the pubis, and the occiput towards the sacrum. The head in this case is expelled just as it is in the oblique position, except that the positions of the fore- 332 TERMINATION OF THE THIRD POSITION. head and vertex, and the anterior and posterior fontanelles, are reversed. If the head takes the second route, the vertex, instead of descending in its original position, or inclining towards the sacrum, rotates upon its perpendicular axis, and the long diame- ter of the head passes first into the transverse diameter of the pelvis, and then into the left oblique diameter. At the comple- tion of this change, the head exactly occupies the second position, with the posterior fontanelle towards the foramen ovale, and the anterior fontanelle towards the left sacro-iliac synchondrosis. The modes in which these two different terminations of the third position are effected are as as follows: The spinous process of the ischium appears to be the deter- mining cause of the ultimate direction of the head in the third position. If the occiput is driven below and behind this point, the head emerges from the pelvis in the position it held at the Fig. 103. Outlet of the Pelvis, and the Foetal Head in the Third Position. The asterisk marks the present- ing portion.—P, the Pubis. commencement of its passage through the pelvis, or nearly so. The forehead is in apposition with the left part of the pubic arch, and the occiput with the right sacro-iliac synchondrosis. The prominence of the occiput is in this case a serious impediment to the passage of the head over the sacral surface and through FIRST AND THIRD POSITIONS CONTRASTED. 333 the perinaeum. When the pelvis and the head are of-average size, the foetal head cannot pass in this position until it has been moulded by the pressure of the sacrum and the uterine pains. Before the head is expelled, the occiput is compressed and the cerebral mass is thrown forwards, so that when the child is born, the forehead is prominent and the occiput depressed. Some authors say that the foetal head seldom or never passes in this direction, except when the pelvis is small and the foetal head large; but I have several times met with examples of the third position in which the head had descended to the perinaeum, in the third position, in cases where the head had been of large size, and in which it was necessary to apply the forceps to effect delivery. When the child is born in the occipito-posterior posi- tion, the forehead, eyes, nose, mouth, and chin successively emerge from under the pubis, and the occiput is forced down the sacral and coccygeal planes, and over the perinaeum. This is represented in the following figure, which may be contrasted with Fig. 99. Fig. 104 Expulsion of the Head in the Occipito-posterior Position. More frequently, the head, on entering in the third position, passes downwards, until the occiput meets the spine of the right ischium, when, instead of passing behind this prominence, it glides in front of it, and, directed by the ischiatic planes, passes downwards and forwards until it occupies the second position. The vertex in this movement travels from the right sacro-iliac 334 MECHANISM OF THE FOURTH POSITION. symphisis to the right foramen ovale. The head is then borne in precisely the same way as though it had originally presented in the second position, or the left oblique diameter of the pelvis. In the Fourth Position, the head enters the pelvis in the left oblique diameter, but the forehead is directed towards the right acetabulum and the occiput towards the left sacro-iliac synchondrosis. Just as the third position is the reverse of the first, so is this the reverse of the second. As the head enters the brim, the occiput and the right side of the base of the fcetal head are depressed, and the right parietal'bone is the lowest point. This is represented in the following figure. Fig. 105. Brim of the Pelvis, and Base of the Foetal Cranium in the Fourth Position. Inferiorly, the sagittal suture runs in the same direction as in the second position; but the anterior fontanelle is divided to- wards the right foramen ovale, and the posterior towards the left sacro-iliac synchondrosis. The right parietal bone is the presenting portion of the head, and the part reached in examin- ation by the finger is the anterior and upper part of the right parietal surface. As in the third position, the vertex may either pass into the hollow of the sacrum, and the head be delivered in the left occipito-posterior position, or it may advance in front of the spine of the left ischium, and be converted into the first position. The latter is the usual termination of presentations in the fourth position, just as delivery in the second position is the usual sequence of presentations in the third position. These are the chief positions in vrhich the head presents and passes through the pelvis in natural cases. Other varieties are YARI.UToNS OK THE FOUR GENERAL POSITIONS. 335 enumerated by some obstetric teachers, such as the descent of the head through the upper part of the pelvis, in the transverse Fig. 106. Outlet of the Pelvis and Foetal Head in the Fourth Position. The asterisk marks the presenting portion.—P, the Pubis. or in the antero-posterior diameters. This would make four other positions, since the occiput may be either on the right or left side in such cases, or placed anteriorly or posteriorly. These varieties need only be mentioned, in regard to the mechanism of natural labor, as they rarely, if ever, occur, ex- cept when the head of the foetus is very small in comparison with the size of the pelvis, or when the pelvis is deformed, and its transverse or antero-posterior diameters considerably in- creased. LECTURE XXII. THE MECHANISM OF LABOR. Gentlemen :—The Mechanism of Parturition, in the seve- ral positions in which the foetal head passes through the pelvis, occupied our attention in the last lecture. It wTould be difficult to exhaust this subject in the course of several lectures. Mechan- ism, Position, and Motor power, in their various relations, are the Elements or Grammar, of the Obstetric Art. It is absolutely necessary that they should be mastered in order to practise mid- wifery with anything like satisfaction. I need not dwell on the difference between the state of mind of a student or young practitioner who, with a case of labor under his hands, knows the exact position of the head, and one who merely knows that the head presents, without being in the least degree awTare of the position in which it may be expected to make its exit. The one will wait the result with the confidence which knowledge alone imparts; the other will be disturbed with fears of something wrong, and anticipations of occipito-posterior births, when nothing of the kind is likely or possible, or with apprehensions of other complications or causes of difficulty and delay. The positions in which the head presents are not most fre- quent in the order in which they are numbered in describing the positions themselves. The presentations in the First Position are more numerous than all the other positions put together. Naegele found the first position to occur in 69 per cent, of the head presentations which came under his observation.' M. Hal- magrand gives 74 per cent., Madame Lachapelle 77 per cent., and Madame Boivin 80 per cent., as the proportion of the first position in head cases. Dr. Simpson found the first position in 256 cases out of 335 cranial cases. The variation between 69 and 80 per cent, is not very great, and as the statistics of these authors extended to 60.000 cases, we may be sure that the fre- 336 naegele's statistics of the positions of the head. 337 quency of the presentation of the head is pretty accurately given in these results. Since the time of Naegehe's observations, the Third Position has been shown to be the next in frequency to the first. In Naegele's own practice, he diagnosed the third position L in 29 per cent, out of 1210 cases. Other authors describe the Second Position as being met with in a greater proportion than that given by Naegele, and they place the second position as being the next in frequency to the first. Naegel6 explains this u by supposing that the occurrence of the third position is fre- quently not ascertained until it has changed into the second posi- tion, and it has then been considered to have been the second position originally. This is in all probability the truth. Madame Boivin describes the second position as occurring in 19 per cent., and Madame Lachapelle in 21 per cent.; while Naegele*, out of more than 1200, cases found it only in .07 per cent. Dr. Simpson remarks that Naegele's observations were made by himself, while those of Madame Boivin and Madame Lachapelle were made by females attached to the Maternite Hospital of Paris. We may, then, conclude that Naegel6's proportions are the most correct, and the observations made subsequently to his own tend strongly to confirm them. Naegele found the Fourth Position to occur only in the small proportion of .03 per cent. Thus we may consider the first position as the most frequent; the third comes next in order ; and the second and fourth are the most rare. In this enumeration, cases occurring originally in the third and changing in the second, are considered as belonging to the third position. While I have no doubt that Naegele was, in the main, correct in his estimate of the great frequency with which the third position changes into the second, I believe a larger number than ^ i he supposes are delivered as occipito-posterior cases.\/ Naegele states, that out of 96 cases in which the head presented originally in the third position, he only observed it to be delivered in the occipito-posterior direction in 3 cases, and in all of these the pelvis was larger than usual, or the head was small and com- pressible. Out of a smaller number of vertex cases in the third position, I have met with two instances in which the labors were very severe, and in which the head passed with the occiput towards the rectum. In the first and third, or the most common positions of the head at the commencement of labor, it will be observed that the 22 • 338 FREQUENCY OF THE LEFT OBLIQUE POSITION. head occupies the left oblique diameter; in the first the occiput being the most anterior part of the head, and in the third the sinciput. In both, the right side of the head is lowest in the pel- vis. As far as I am aware, no other reason can be given for the greater frequency of presentations in the left oblique position with the right side of the fcetal head downwards, than the greater strength of the right limbs, and the occupation of the right ob- lique diameter by the rectum. It is necessary that what is meant by the presenting part of the foetal head should be clearly defined. Hitherto, a good deal of confusion Iras prevailed upon this subject. Is it the part found most prominent within the ring formed by the soft parts of the parturient canal in the different stages of labor—namely, the os uteri, the vagina, and the ostium vaginae ? Is it the part of the head found lowest in the pelvis during the progress of labor ? Is it the part first met with on introducing the finger into the pelvis, in the direction of its axis ? It will be found that all these points of view are mixed up together, in some of the best and most recent works on obstetrics, with the effect of causing considerable confusion. For instance, the right tuber parietale is very commonly said to be the presenting part in the first and fourth positions, as the head passes through the brim and upper part of the pelvis, because it is the lowest point met with on introducing the finger into the vagina. It is, however, .more frequently, indeed almost invariably, felt through the ante- rior wall of the cervix, and not within the ring of the os uteri, unless after the full dilatation of the latter. I would surest that it would be best to define the presenting part in every kind of cranial position or presentation, as that portion of the foetal head felt most prominently within the circle of the os uteri, the vagina, and the ostium vaginae, in the successive stages of labor. We may consider the right and left tuberosities of the parietal bones as points common to the positions in which the occiput is found either on the right or the left side of the pelvis respect- , ively. That is, in the first and fourth positions, the occiput is in one case in the early part of labor in the neighborhood of the left acetabulum, and in the other near the left sacro-iliac syn- chondrosis. In both, the right tuber parietale is the lowest point of the fcetal head, in the early part of labor. In the • WHAT IS THE PRESENTING PORTION OF THE HEAD. 339 second and third positions, the occiput is turned towards either , the right acetabulum or the right sacro-iliac synchondrosis. In both, the left tuber parietale is lowest in the pelvis. In the first position, when the os uteri is open to the extent of, say an inch in diameter, the part felt within the circle of the os is the upper and nearly the middle portion of the right parietal bone. As labor advances, the part of the head in the centre of the dilated os uteri is the middle portion of the posterior and upper quarter of the same bone. AVhen the os is sufficiently open, the right tuber and the right ear may be felt. As the head advances through the vagina and presents at the outlet, it is the upper and posterior angle of the bone which is most prominent. It is upon these parts in succession that the tumor of the scalp or caput succedaneum is formed by the pressure of the os uteri and the other portions of the parturient canal upon the foetal head. The tumor of the scalp formed upon the middle ,v- of the upper half of the right parietal bone by the os uteri, may be called the primary caput succedaneum. When the os uteri is rigid, the swelling marks the foetal head very distinctly, and if the subsequent part of the labor should be easy and rapid, there may be no other tumor. If the latter part of labor should be difficult, a swelling of the scalp is formed over the posterior and superior angle of the right parietal bone. This may be called the secondary tumor. Sometimes the dilatation of the os uteri is so easy, and the compression of the scalp so slight, that no primary tumor is formed. In other cases a tumid ridge extends from the middle of the upper border of the right parietal bone to its posterior and superior angle, or even to the upper portion of the occipital bone. In the fourth position, the part first felt within the os uteri, as the head lies in the left oblique diameter, with the occiput towards the left sacro-iliac synchondrosis, is the middle of the upper portion of the right parietal bone, very nearly, in fact, the same point as is felt in the first position. It is here that the primary tumor of the scalp is formed. The sagittal suture is, however, nearly in the direction of the left oblique diameter, the anterior fontanelle is directed towards the right acetabulum, and the posterior fontanelle towards the left sacro-iliac synchondrosis. In the first position the sagittal suture, it will be borne in mind, runs nearly in the direction of the right oblique diameter. 340 ANALYSIS OF THE TERMINATIONS OF VARIOUS POSITIONS. It has been shown that the head, when presenting in the fourth position, may descend through, and emerge from, the pelvis, in two modes. The occiput may turn towards the hollow of the sacrum, in wrhich case the frontal bone approaches the left side of the pubic arch; or, as we have seen, the occiput may turn forwards and make a quarter, or rather more than a quarter turn, so as to approach the left portion of the pubic arch. In the first termination, the anterior and upper portion of the right parietal bone passes first through the vagina, and emerges underneath the arch of the pubis. It is upon this point that the secondary caput succedaneum is formed. Sometimes this over- laps the posterior part of the right frontal bone, and some portion of the anterior fontanelle. In the second termination of the fourth position, the parts of the head present in almost precisely the same order as in the first position, and the tumor of the scalp is formed in the same sites. The change is from the middle and upper portion of the right parietal bone to the posterior and upper angle of the same bone. In the second and third positions, the presenting parts of the fcetal head and the tumors of the scalp are the same as in the first and fourth, only it is the several parts of the left parietal bone, instead of the right. In the second position, the middle of the upper portion of the left parietal bone presents in the first instance, and movements of rotation and advance gradually bring the posterior and upper portion of the parietal bone to be the site of presentation under the left portion of the upper part of the pubic arch. In the third position, it is the middle and upper portion of the left parietal bone which presents within the area of the dilating os uteri. In the first and common ter- mination of this position, the head, in making its quarter turn, so as to bring the occiput to the right foramen ovale, brings the same parts of the left parietal bone into presentation, as in the second position. In the second termination of the third position, the turn to the extent of one-eight of the circumference of the pelvis brings the anterior and upper part of the left parietal bone to be the presenting part, and this is the first portion of the head to emerge under the pubis in such cases. As the vertex is not the first part to be delivered in occipito- anterior cases, but the posterior and upper part of the right and THE SCREW MECHANISM OF LABOR. 341 left parietal bone, it follows that in the labors occurring in the first position and in the occipito-anterior termination of the fourth position, it is the right tuber parietale which is first delivered. When this has passed through the ostium vaginae, the circle of the outlet intersects the head between the two tuberosities in a diagonal direction. The same occurs with respect to the left tuber parietale in the second position, and in the occipito-ante- rior termination of the third position. So, also, in occipito-pos- terior deliveries, the two tuberosities do not pass through at the same time. In the fourth position it is the left, and the third the right, tuber which first escapes. Thus the bi-parietal diameter of the head always passes through the pelvis and soft parts in an oblique direction, so that the largest lateral diameter never engages the opposite sides of the canal at the same time. The moulding of the foetal head during a severe labor is pecu- liar in the different positions. In the occipito-posterior positions, the mass of the brain and the cranium are so moulded that the anterior or frontal end of the cranial ovoid becomes larger than the occipital. In the fourth occipito-anterior position, the right, and in the third, the left, side of the frontal region is the most prominent. In the first, and the occipito-anterior terminations of the fourth positions, the head is moulded so as to make the right side of the head, and especially the right side of the occi- pital and posterior parietal regions the most prominent. In the second, and the occipito-anterior terminations of the third, the same prominence is impressed upon the left and posterior por- tion of the foetal head. Dr. Swayne, of Bristol, has pointed out that in occipito-posterior positions, a vacant space may be felt under the pubic arch, owing to the small size of the frontal part of the head before it has been moulded by the pressure of parturition. On former occasions I have referred to the principle of the Screw, which obtains in the pelvis, and to the screw-like, spiral, or rotatory movement of the foetal head in passing through the pelvis in the different cranial positions. It has not hitherto been made out, but I believe the mechanism of the pelvis and the fcetal head to be precisely that of a body moving down a spiral inclined plane or screw. A screw is an inclined plane, arranged in a spiral form, either round a solid cylinder, or upon the inter- nal surface of a hollow cylinder. When the one is fitted into 312 THE FCETAL HEAD THE MALE SCREW. the other, the spiral arranged round the solid cylinder is called the male, and that around the hollow cylinder, the female screw. Fig. 107. R. Right parietal bone. L. Left parietal bone. 1. 1. 1. The different points of the right parietal bone which present successively in the first posi- tion. 4. The part of the parietal bone which presents at the os uteri, in the fourth position at the com- mencement of labor. 4 a. Tlie part of the parietal bone which presents at the ostium vaginae, in the fourth position, when the head is delivered in the occipito-posterior position. 4 b, 4 6, The points of the right parietal bone which present successively when the heacj, pre- senting in the fourkh position, makes the quarter turn, and is delivered in the oecipito-anterior posi- tion. The figures 2, 3, 3 a, and 3 b, 3 6, mark in the same way, the presenting points in the second and third positions of the head, on the left parietal bone. The two diagonal lines across tjhe head mark the intersection of the head by the vulva and peri- naeum, as the head passes out, so that only one tuber parietale occupies the ostium vaginas at the same time. In the mechanics of parturition, the pelvis plays the part of the female, and the fcetal head the part of the male screw; and it is by the movement of the one within the other, in a spiral direction, that the head passes, so as to meet with the least possible mechanical resistance from the pelvis and soft parts. The transverse, oblique, and antero-posterior diameters are successively the longest diameters, in passing from the brim of the pelvis to the outlet. The fcetal head, being of oblong shape, can only pass by entering the brim in a position approaching to the transverse, and descending with the long diameter of the head in relation, first with the oblique diameter, and then with THE PELVIS THE FEMALE SCREW. 343 the antero-posterior diameter of the pelvis, or very nearly so. Such is, in reality, the direction in which the head moves. If we were to place a number of pelves one above another, we should represent pretty correctly the chamber of a female screw; and a line drawn through the long diameters of the various planes would form a spiral, and mark the path of the groove, or thread, as it is termed, of the screw. In the single pelvis, aline drawn from the transverse, through the oblique, and towards the antero-posterior diameters, would mark the path of the por- tion of the spiral through which the fcetal head moves in partu- rition. This, in the case of the first position, is somewhat more than one-eighth of a circle. The arrangement of the fcetal head with reference to the trunk favors this rotation. The- spiral incline of the pelvis impresses itself upon the foetal cranium as the head of the male screw, and this rotation is facilitated by the ease with which the head of the foetus moves upon the neck. The pelvis represents a portion of a female screw, admitting a male screw (the fcetal head), of an oblong shape. But the male and female screws in the case of the pelvis and foetal head, 4/ v are not accurately adjusted at all points. There is, however, a general adjustment in the shape of the fcetal head and the arrangement of the pelvic diameters. It is only at the points where the posterior part of the parietal bone, or of the occiput, comes in contact with the planes of the ischium and pubis, that the thread of the male screw bites, as it were, the thread of the female. It is here that the spiral direction is impressed upon the foetal cranium. The line of this portion of the spiral or screw may be made out by chalking the salient point of the fcetal head, and moving it through the pelvis in the direction it takes in parturition. The chalk line marked upon the pelvis by this proceeding will show, accurately, the track of the segment of the thread or groove of the female screw, through which the prominent portion of the head passes. The two halves of the pelvis also represent portions of two screws, the inclined planes of which are arranged in opposite directions. Thus, if the head be placed in the second position, the spiral movement is reversed from that which obtains in the first position, and the long diameter of the fcetal cranium moves from the transverse, or the left oblique, to the antero-posterior diameter. In the case of labor occurring in the first, the right 344 SPIRAL MOTION OF FCETUS. shoulder moves upon the right portion of the spiral or screw formed by the right ischium and pubis, and glides down it, just as the head does in the second position. In the second position, on the contrary, after the delivery of the head, the left shoulder rotates upon the planes of the screw or spiral of the left side of the pelvis, and passes out with a movement similar to that which belongs to the head in the first position. Perhaps the screw or spiral motion is seen still more distinctly in the common terminations of the third and fourth positions. Here, rather more than one-fourth of a circle is completed in the movement which brings the occiput from the right or left sacro- iliac synchondrosis, to the right or left ramus of the pubic arch. The movement is distinctly spiral, only that when the head pre- sents in the occipito-posterior position, it has to pass through a spiral having a larger diameter than when the head presents in the occipito-anterior position. The two lines marked upon the following diagram mark the different paths through which the head glides when it presents in the first and fourth position, and passes towards the antero-posterior diameters. In both it is dis- tinctly screw-like, or spiral. A similar diagram of the right side of the pelvis would give the. lines of the spirals traversed \ Fig. 108. Outline of the internal surface of the left half of the pelvis. The two curved lines mark the path of the head in the first, and in the occipito-anterior termination of the fourth positions. by the head in the second and in the third positions, when the head is born in the occipito-anterior position. SPIRAL DIRECTION DEPENDENT ON THE BONY SURFACES. 345 The contractions of the uterus and abdominal muscles consti- tute the vis a tergo which moves the fcetal head down the planes of the ischium and pubis. No rotatory movement appears to be t^ given to the foetal head by the pains. The spiral direction ^ depends entirely upon the portion of the spiral inclined plane formed by the osseous surfaces. If any weight or pressure be placed upon a male screw, adjusted in the chamber or box of the female, it has the tendency to descend the spiral plane. We see this familiarly exemplified in the press for stamping letters, in which a weight at the top of the screw causes it to descend. In practice, these considerations are important with reference to the direction in which traction can be used to the greatest advantage in delivery by the long or short forceps ; rectifying the positions of the head in the case of presentations in the third or fourth positions ; and in other operative proceedings. LECTURE XXIII. THE STAGES OF LABOR. Gentlemen :—I have been accustomed to divide Labor into a Preliminary and a Supplemental Stage, and the three principal stages of Dilatation, Propulsion, and Expulsion. In the Preliminary or preparatory Stage, the uterus and other organs become fitted for the commencement of actual labor. For two or three weeks before the date of parturition there is a subsidence of the abdominal tumor, the womb sinks into the pelvis; the waist, in consequence, becomes smaller, and the respiration and general mobility are less oppressed. A few days before the accession of labor, the subsidence of the uterus is still more remarkable, and it now begins to contract in an equable and continuous manner, as though gathering itself up for the coming effort. The contraction of the uterus is moderate, but it is not always paroxysmal, or attended by uterine pain. In the preliminary stage of labor there is the persistent contraction of the whole of the uterus, which has just been referred to; the uterus becomes firm and ovoid, and is more readily distinguishable from the rest of the abdominal contents than before. The abdominal tumor now becomes distinctly uterine. Owing to the persistent contraction of the uterus, the mother sometimes misses the rolling movements of the uterus, and imagines the child to be dead. Besides the persistent uterine contraction, there is usually an irritable state of the sphincters of the rectum and bladder. The bowels are generally opened two or. three times, and there is a frequent desire to evacuate the bladder. The effect of these actions of the bladder and the intestines is to free the pelvis and the lower part of the abdomen from all unnecessary incum- brance, and thus to give room to the parturient canal. As the DILATATION OF THE OS AND CERVIX UTERI. 347 pains commence there is usually a sanguineous discharge, termed the " show," but this is not invariably present. In the Stage of Dilatation, the os uteri is opened, so as to admit the passage of the foetal head. In this process of expansion, the os and cervix uteri are to a certain extent obliterated, and the uterus and vagina become one continuous canal. In a preceding lecture I have dwelt on the mode in which this dilatation is effected, partly by the influ- ence of the contraction of the body and fundus upon the os uteri, partly by the fluid pressure of the amniotic bag and partly by the active dilatation and relaxation of the circular fibres or imperfect sphincter of the os itself. The direction in which the motor force of the uterus is at Fra 109. The cavity of the Uterus, with the Parturient Canal in a state of full dilatation. first exerted is downwards and backwards, in the direction of the axis of the uterus, and the axis of the inlet of the pelvis. The dilatation of the os uteri tends, by reflex action, to dilate the cardia, and it often goes to produce .actual vomiting. 348 RUPTURE OF THE MEMBRANES. When the stomach is emptied of its contents, the freedom of the respiratory movements is increased, and the dilatation of the par- turient canal is promoted. Sickness is sometimes present during the whole of this stage, but, if not, it frequently appears at the time of the complete dilatation of the os uteri. It is not a little remarkable, that in the early part of dilata- tion the excitor nerves affected by the pressure of the mem- branes and fcetal head should be chiefly in relation Math the lower medulla and the uterus, while those which come to be excited at the time of full dilatation of the os uteri should affect the medulla oblongata, and the muscles engaged in the act of vomit- ing, including a considerable number of the muscles of respira- tion. Another singular affection of the muscular system now occurs. A very distinct shivering, or rigor of the muscles, is often observed at the time when the os uteri is completely dilated. This rigor is very similar to the shuddering produced by the dilatation of other sphincteric muscles. Many persons experience this when the first morsel of food at a meal is passing the cardia, when the urine first passes in micturition, or when a catheter is passed, or when the sphincter ani first dilates. These rigors, accompanying the full dilatation of the os uteri, are sometimes so severe and continued as to excite alarm, lest they should pass into general convulsions ; and this is, in fact, one of the modes in which the invasion of the puerperal con- vulsion occurs. The last act of the stage of dilatation is the rupture of the mem- branes, and the entire or partial discharge of the liquor amnii. The membranes having acted as an efficient dilator of the os uteri, as far as it dilates by mechanical distension, suddenly give way, and the uterus becomes smaller in compass, contracting more closely and powerfully upon the foetus. As long as the membranes are unbroken, the circulation in the uterus is not materially interfered with, and the contractions are not so powerful as they afterwards become, on account of the disad- vantages under which the uterine fibres act. But as soon as the waters are discharged or diminished, the uterus contracts more closely upon the foetus, and prepares itself for the stage of pro- pulsion, which we shall next have to consider. The circulation in the uterus, and consequently the changes going on in the pla- centa, are then considerably interfered with; so that the stage EXPIRATORY PROPULSIVE ACTIONS. 349 of propulsion is of much greater moment to the life of the foetus than the stage of dilatation, which is now brought to a conclusion. In the Stage of Propulsion, the presenting part of the child is passed on from the middle portion of the pelvis to the ostium vaginae. At the time when this stage of labor commences—namely the point at which the liquor amnii is discharged, and the os uteri becomes fully dilated, the motor force of parturition is applied in quite anew direction. The direction in which the foetus has now to pass is in that of the axis of the outlet of the pelvis, which is forwards and downwards. It is at this point that the expiratory muscles come into play, particularly the abdominal muscles, and thus the new direction is provided for. Before the dilata- tion of the os uteri, we had to consider the foetus as an ovoid mass, and the axis of this ovoid was the same as the axis of the uterus, and as the axis of the inlet of the pelvis. After the dila- tation, we may speak of two axes of the foetus—one, the axis of the head, in its long or occipito-mental diameter ; the other, the axis of the body of the foetus. Now, this axis of the head, in a natural presentation, becomes nearly the same as the axis of the outlet of the pelvis, through which it has to traverse ; and the foetal body being flexible, readily passes, as it descends, from the direction of the superior to that of the inferior pelvic axis. All these correspondences cannot fail to strike the atten- tion, but they are only a few of those which accompany this stage of parturition. I have already mentioned the advantage given to the uterus by the rupture of the membranes. The same circumstance is equally favorable to the action of the abdominal muscles. A further adaptation, therefore, becomes visible in the pre- cise time at which the liquor amnii is discharged. When the bulk of the uterus is increased by the liquor amnii in addition to the foetus, the abdominal muscles are so distended that they could only act with difficulty. But after the diminu- tion of the size of the uterus by the discharge of the waters, the abdominal muscles are more free to act, and it is now that they are called upon to aid in the expiratory actions which propel the head of the child through the vagina. When voluntary movements of expiration are unadvisedly made during the 350 EXPIRATORY ACTION, REFLEX. stage of dilatation, they are always awkward and fatiguing to the patient; but during the stage of propulsion, the contractions of the abdominal muscles are so powerful as to be no inconsider- able stimulus to the uterus itself. I mean, that besides their direct expulsive power, the pressure they exert upon the uterus excites this organ to more powerful action. Thus, in this stage of labor, when the uterine contractions flag, they can sometimes be renewed by voluntary contractions of the expiratory mus- cles. But there is a cause for the intervention of the respiratory system as well as the sign of its utility. In the stage of dilata- tion the ovarian and uterine nerves were the chief amongst the excitor nerves of the motor actions which then occurred. As soon, however, as the fcetal head, protruding through the os uteri, begins to press upon the vaginal surface, a new set of excitor nerves becomes implicated. These nerves are the excitors of the expiratory actions of parturition. As long as the internal surface of the uterus alone is irritated, whether by the foetus, a polypus, or other bodies, the uterus contracts by itself; but as soon as the vagina is impinged upon, the expiratory force is brought to bear. Another point worthy of observation is that the excitor nerves of the uterus, except at the extreme dilatation of the os uteri, when the stomach was disturbed, were in con- nection with the lower portion of the true spinal marrow only; but the vaginal excitor nerves are in relation both with the lower medulla and the medulla oblongata. By the lower medulla, and the excitor and motor nerves in relation with it, reflex actions of the uterus are produced by excitation of these nerve3 ; while all the reflex actions of the respiratory system depend upon the medulla oblongata. If the spinal marrow were divided in the middle, there would probably be no respiratory action in partu- rition, unless the pneumogastric can act as an excitor during labor. Voluntary efforts, and the forcible efforts of emotion, are often mixed up with the pains ; but the respiratory acts of this stage of labor are truly reflex in their nature. The expiratory actions occur during the insensibility of puerperal convulsions, when emotion and volition are both suspended. If they were not reflex and physical in their nature, the exhaustion following a strong labor would be far greater than it is. It is a principle of reflex action that it induces no fatigue. Hence we see even EXPIRATORY ACTION, VOLUNTARY. 351 weakly women making powerful efforts, but perfectly refreshed between the pains, and easy and composed after several hours of severe labor, complaining of nothing beyond the mere soreness of the muscles consequent upon their energetic contractions. It may be well to describe minutely the motor phenomena of the contractile part of a pain in this stage. At the coming on of each pain, the patient takes a deep inspiration, as a prelim- inary. Expiration then takes place slowly and forcibly, in a suc- cession of gasps, and when the air in the thorax is diminished, it is suddenly renewed by hasty inspirations. Each pain con- sists, as far as the respiratory muscles are concerned, of several sudden and deep inspirations, followed by prolonged and laborious expiratory efforts, with the glottis partially or entirely closed. At the acme of a pain in this stage of labor, the glottis and cardia are entirely closed, the glottis only opening partially at intervals, and the abdominal and all the other ordinary and extraordinary muscles of expiration being forcibly contracted. The diaphragm remains inert, as in vomiting, with the actions of which, except that the cardia is closed instead of opened, the efforts of the expiratory muscles in labor may be compared. Obstetric writers have taught that the diaphragm contracts in this stage; but if it be considered for a moment that the dia- phragm is a muscle of inspiration, while the actions of parturi- tion are expiratory, the fallacy of such a view of the action of the diaphragm must at once appear. Of the contraction of the abdominal muscles during this stage of labor there can be no doubt; and the actions of the diaphragm and abdominal mus- cles are antagonistic. It is true that the floor of the diaphragm, instead of being arched as in an ordinary state of relaxation, remains plane during the efforts of inspiration, with the glottis closed: but this is from the mechanical distension of the chest by the contained air, not from an active contraction of the mus- cle itself. Besides these actions which are involuntary and reflex, the patient voluntarily aids in fixing the thorax, by hold- ing some fixed body with her hands, or planting her feet firmly. More than this, she increases all the expiratory actions by strong efforts of the will, and by that emotion of labor which impels her to brave every suffering to effect the birth of the child. At length, when the pain can no longer be borne, the short gasp or groan is exchanged for a cry which dilates the 352 DILATATION OF THE PERINvEUM. glottis, and the pain and contractions subside. This cry is a motor action, excited by the emotion of pain,, and instantly relieves the uterus of all extra-uterine pressure. Thus, the glottis may be compared to a safety-valve, which is thrown open by emotion whenever the pressure becomes more than can be borne with safety. By the influence of volition we have this valve entirely under our control, to open or close it as may be necessary. When the expiratory actions are weak, we can enjoin the patient to hold her breath, and when they are too intense and too long continued, we can encourage her to cry out, which is of course equivalent to dilating the glottis, and expir- ing the contents of the thorax. During all this time the uterus contracts powerfully. The dilatation of the perinaeum is an im- portant part of this stage of labor. In a former lecture I pointed out the provisions which exist for the dilatation of this part of the parturient canal in the arrangement and attachments of the perinaeal muscles. The dilatation, thus favored, is effected by the wedge-like action of the head. Throughout the whole of labor the passages are plentifully lubricated by the bland alkaline mucus secreted by the glands of the canal of the cervix. In the Stage of Expulsion, the different parts of the foetus are successively expelled through the ostium vaginae, the outlet formed by the vulva, the pubic arch, and the perinaeum. This stage of labor is the shortest of the whole progress, but it is the most important and decisive of all. The actions of the propulsive stage continue with unabated vigor. The uterus contracts with full power, and the respiratory muscles act with immense force. The intervals between the pains diminish as the close of the struggle approaches ; and there is often a perfect storm of uterine contractions, without sufficient intermission to enable us to say distinctly where one pain ends and its successor begins. When the foetal head is actually passing the ostium vaginae, a new set of actions make their appearance. The perinaeum, after being distended to the utmost, is now retracted over the head by the action of the levatores ani; the sphincter ani and sphincter vesicae dilate suddenly, the vagina contracts upon the advancing mass, and the head glides rapidly into the world. The dilatation of the two sphincters, between which the vagina is placed, compensates admirably for the absence of a PARTURITION, A VOLUMINOUS MOTOR FUNCTION. 353 perfect sphincteric muscle at the outlet of the parturient canal. The effect of this double dilatation is, that at the precise moment when there is the most imminent danger of laceration, there is a sudden and considerable removal of tension from the parts en- dangered. The dilatation of the sphincters is partly dependent on the sensation and emotion of severe pain, and partly on the reflex dilatation peculiar to the sphincteric muscles. This view of the subject gives importance to the defecation, which fre- quently occurs at this time, and which has been looked upon only as a disagreeable contretemps. Physiology here, as in many other instances, transmutes the meanest actions of the economy, and renders them noble by virtue of their uses. At the same moment that the orifices of the rectum and bladder are thrown widely open, there is generally a dilatation of the glottis. Even from women who restrain the expression of their emotions during the rest of labor, a cry of pain escapes at this juncture; this cry is necessarily accompanied by an open state of the glottis. The opening of the glottis is not at all accidental or voluntary, but is as regular and involuntary as its closure during the propul- sive pains. Its effect is suddenly to take away the expiratory pres- sure from the expulsive action. Without this combined action of the glottis, and the sphincters of the rectum and bladder, for the defence of the ostium vaginae, recto-vaginal laceration must be a more common accident of parturition. Such would inevit- ably be the frequent result of closure of the abdominal and thoracic cavities at all points, except that of the point of exit for the foetus, in the final throes of labor. Altogether, it must be conceded that parturition is the most voluminous of all the motor functions. The human uterus con- tracts sometimes sufficiently to render the hand of a strong man powerless. In order to illustrate the wonderful muscular power of the heart, the circulation in the whale or the elephant is often referred to by physiologists; but enormous as is the power of the heart, in these animals, the parturient actions by which they bring forth their enormous young, give us the most colossal idea we can entertain of any single muscular action. In the human subject, too, there is a certain grandeur in the combined efforts brought into play in parturition. In women, even of moderate strength and stature, every voluntary muscle of the body is in strong action ; the excito-motor force is in a state of the greatest 23 354 HOW THE PLACENTA IS DETACHED. activity ; the uterus, unseen, and without any participation with the will, is making its immense contractions ; and emotion im- parts strength to both voluntary and reflex actions. A temporary calm follows the energetic actions which issued in the delivery of the mother. After the excessive action, in which nerve and muscle seemed strained to the utmost pitch, there comes a sudden and profound repose; there is perfect freedom from pain; every fibre is relaxed ; only the uterus now contracts, of all the muscles which were so lately struggling. Like some ship which turns from a tempestuous sea into a safe and quiet harbor, the new mother passes from the storm of childbirth into the tranquil haven of maternity. In the pathetic words of Scripture, " A woman when she is in travail hath sor- row, because her hour is come : but as soon as she is delivered of the child, she remembereth no more the anguish, for joy that a man is born into the world." In the Supplemental stage, the placenta is detached and thrown off, and the uterus contracted, so as to prevent the occur- rence of haemorrhage. While the body of the child is born by the motor actions I have been describing, the contracting uterus follows closely upon it in its descent, and the action of the liter in, excited at this time from the immense irritation of the vagina by the advancing foetus, is frequently sufficient to throw off the placenta, and lodge it in the upper part of the vagina. When the pla- centa is not separated in this way by the last expulsive pain, it remains quietly in the uterus until the appearance of the first after-pain. During this interval the uterus contracts with toler- able firmness, under the influence of the excitement of the act of expulsion. If the placenta has been expelled into the vagina, its presence in this situation excites, after awhile, bearing-down pains and contraction of the vagina, similar to those of propul- sion and expulsion, only far more inconsiderable, generally requiring slight traction of the cord to complete its removal. When the placenta remains in utero, it becomes separated from the uterine surface by the contractions of the uterus, and by the arrest of the circulation in the umbilical cord. It is then removed by a miniature copy of labor itself; there is a dilatation of the os uteri, and there are the propulsive and expulsive actions of the uterus and the expiratory muscles on a small scale. IRRITABILITY OF THE UTERUS AFTER LABOR. 355 After the expulsion of the foetus, the first act of the uterus is to contract, so as to prevent the occurrence of haemorrhage. This contraction is induced, in the first instance, by the conclud- ing irritation of the vagina and perinaeum on the exit of the foetus. It is subsequently insured by a succession of stimuli. Of these some are uterine, others are extra-uterine. The bulk of the placenta and membranes irritate, in the first place, the now contracted uterine surface. When placental separation has occurred, the abraded surface of the uterus is intensely excitor; and as the placental mass passes through the vaginal passage and ostium vaginae, excitation, which insures full uterine con- traction, is supplied. It is a peculiarity of the utero-vaginal canal that at the termination of labor all the surfaces are more instantly excitor, and the answering motor contractions become rapid and more easily provoked. During severe labor, irritation of the os uteri, or of the vaginae, will often increase the pains only in a moderate degree ; but now the introduction of the hand into the vagina, and irritation of the os uteri, will excite instant and forcible contraction of the uterus. The extra-uterine excitors of uterine action also come into play in a remarkable manner. As soon as the child is put to the breast, the slight irritation of the mammary excitor nerves excites distinct con- tractions of the uterus. This reflex relation from the breast to the uterus continues for several days after parturition, until, in fact, the uterus has returned to the natural state. As soon as the secretion of milk is established, there is, at every afflux of blood to the breasts causing the sensation termed by women " the draughts," an answering contraction of the uterus. A reflex relation between the stomach and the uterus is also now set up every tirhe the patient drinks her gruel, or takes her tea, sharp contractions of the uterus, after-pains, in fact, are excited. Emotion is another aid to the permanent contraction of the uterus. Any emotion of the mind will generally produce an after-pain, but the maternal emotion especially. The emotion produced in the mind of the mother by suckling her infant induces contraction. A day or two after labor, merely present- ing the infant to the mother without its actual application to the breasts, will excite the sensation of the draught in the mammae, accompanied by a sudden secretion of milk and also by contrac- tion of the uterus. Thus the close of labor, the return of the 356 THE CLOSE OF LABOR. uterine system to the quiet of the unimpregnated condition, is as plentifully provided for as the commencement, or any of the various stages of the process. For some days after labor the contraction of the uterus is of an active sphincteric kind, but its vascular and other tissues rapidly diminish in size, and it soon becomes, to a great extent, a non-motor organ, as it was before the time of conception. LECTURE XXIV. THE MANAGEMENT OF NATURAL LABOR. Gentlemen :—The first summons to a lying-in woman should always be promptly obeyed. Some women alarm themselves before labor has really commenced, or when their labors are going on slowly; others defer sending for the accoucheur until the labor is far advanced, or parturition may take place so rapidly, that the medical man, even when using the greatest promptitude, may be too late, or arrive only just in time to afford his assistance. We should always act in practice as though our cases were those of the latter kind, on the ground that it is much better to be many times too soon than once too late. If we are called unnecessarily early, we can leave the patient confidently for a time; but the attendant is sure to obtain blame should anything go wrong before his arrival. Another rule for the accoucheur should be, that of never leaving one case for another, after he has commenced his attendance upon the first, as he is legally and morally responsible, in the event of accident, for the conduct of any case the actual atten- dance upon which he has undertaken. The matters required by the accoucheur during the con- duct of a labor are, a case containing a blunt-pointed scissors, a silver or gum-elastic female catheter, laudanum, sal volatile, and ergot of rye. The nurse should provide thread for tying the funis, an abdominal bandage, and a supply of napkins and towels, and hot and cold water. At the first visit to a patient in whom labor has apparently commenced, an examination should, if possible, be made. This should not be proposed abruptly, particularly when the ac- coucheur is not well known to his patient. Inquiries may be made about the state of the bowels and bladder, the nature of former labors in multiparous cases, and other points upon which 35T 358 POSITION OF THE WOMAN IN LABOR. it may be well to have information. The accoucheur should not, however, on any account, leave the patient without ascer- taining the nature of the case under his management. It may happen that no pregnancy exists; or the case may be one of arm ' or funis presentation, requiring early interference, with a view to the safety of the mother or the foetus. But in the most natural cases, it is always a comfort and groirnd of confidence to the patient, and a satisfaction to the accoucheur, to know that everything is "Right," as the phrase is, when the head presents. The usual obstetric position in this country is that in which the lying-in woman is placed on her left side, with her head upon a pillow, and the thighs and legs flexed. She should be placed with her back towards the edge of the right side of the bed. [The older practitioners of this country, whose teaching and habits came from English sources exclusively, are in the habit of thus placing their patients; but the teaching in perhaps all our schools at the present day, in conformity with French and German customs, directs the student to place the woman upon the back with the knees drawn up, and any accoucheur who has made a fair trial of this position will not willingly return to the former. The advantages to the accoucheur are convenience in making the examination, and its efficiency, inasmuch as the pulp of the finger instead of the back of the nail, meets the presenting portion ; the comparatively little change of position required in case of an operation becoming necessary, and finally the greater ease found by the patient herself. The attendant should not, however, insist upon any position being rigidly maintained, but should allow such movement as may be desired by the poor sufferer. Too often the attending physician seems to forget the awful suffering of his patient while thinking of some petty twist of his own back or inconvenient position of his own arm. A change of position during the labor is not unfrequently fol- lowed by a renewal of suspended or flagging pains. Occasion- ally, as if some obstacle had been removed by the change of posture, a delayed rotation is effected, and the child is speedily delivered.] In the stage of dilatation, before the os uteri has opened, and when the pains are not immoderate, the patient may be allowed to choose her own posture, except during an examination. She PRELIMINARY PHYSICAL EXAMINATION. 359 may walk about, and occupy herself with the preparations for the coming infant, or other casual matters. The pains may be borne in a sitting or standing position, as may seem most easy. No voluntary efforts or straining at this time should be permitted. The more freedom we allow, of course in moderation, to the patient during this stage, the less fatigue she will feel during the succeeding stages of labor. When the stages of propulsion are proceeding, she should be advised to lie upon her left side in the manner already pointed out. This seems to be the most convenient position, and the one assumed by women in a state of nature, or in cases where women are delivered without assist- ance. But, even after the stage of dilatation has passed, no great constraint should be exercised. If the labor be long, women become cramped and sore from continuing several hours in the same position, and the pressure exerted by the foetus is more distressing than when occasional change of posture is allowed. Amongst poor women in this country, the usual dress is worn until the completion of labor. With the rich, the custom is either to wear a dressing-gown during the stage of dilatation, or to remain in bed during the whole of labor. The bed should be prepared by the nurse with a drawn sheet, and a leather or piece of india-rubber sheeting, to defend it from the discharges. In " Taking a pain," as it is termed, the accoucheur sits or stands by the side of the bed, the patient's back being towards him. This is one advantage in the position on the left side, as it enables the attendant to make the necessary manipulations while her face is turned away from him. With an expert and careful nurse, the patient will be placed on her side, and the clothes so arranged that a little fold of the chemise or night- dress will be brought to the edge of the bed, along which the accoucheur can introduce his hand without impediment until it reaches the vulva. In other cases, the dress may be wrapped round the legs, and the attendant has to disentangle it before he can make the necessary examination. The position of the hips are obvious, and the better plan for the student is to introduce the right hand between or at the back of the heels, and pass it up towards the nates. The posterior fourchette should be felt for, the vulva separated by the two forefingers or the finger and thumb, and the forefinger introduced along the vagina in the direction of the axis of the pelvic outlet. The experienced 360 METHOD OF MAKING AN EXAMINATION. accoucheur will have little difficulty in passing his hand straight to the vulva without any such precautions. Guiding the finger along the vagina, the os uteri is felt, in the early part of labor, pointing towards the upper part of the sacrum, and the presentation can be made out as described when treating of the mechanism of labor. If the os uteri cannot be reached with the forefinger of the right hand, the two forefingers of the left hand should be intro- duced, as they can be passed higher than the forefinger of the right hand. Some distinguished obstetricians always use the second finger of the right hand, because of its length ; others, the two first fingers of the same hand, with a view to trying the dilatability of the os uteri and vagina. As a rule, no opinion respecting the presentation should be given unless the finger can be passed within the os uteri, and the presenting part felt, either by itself or through the membranes. If the young accoucheur contents himself with feeling the presenting part through the anterior wall of the cervix uteri, without getting within the os, he may sometimes mistake the back or shoulder for the head, and have to make some awkward explanations to the patient or those around in case of such an error. Besides ascertaining the exact presentation, we acquire by the first examination a knowledge of the state of the os uteri, the extent of its dilatation, its dilatability, the condition of the vagina and perinaeum as re- gards sensibility and distensibility, the amount of lubricating secretion in the passages, the state of the rectum as regards fullness or emptiness, the capacity of the pelvis, and some general idea of the size and state of ossification of the fcetal head, the tumor of the scalp, the rupture or integrity of the membranes, the quantity of liquor amnii, the height of the presenting part in the pelvis, etc. In all examinations, the fingers used should be smeared with cold cream, olive oil, or glycerine. As a general rule, the forefinger is the one most conveniently used by the accoucheur, but no representation which I have seen accu- rately portrays the mode in which it is used in an examination. In an examination in the early part of labor, when the os uteri is high in the pelvis, the arm and wrist are rotated so that the palmar surface of the base of the finger comes almost in contact with the pubis, and the os uteri is explored with the radial and middle surface of the pulp of the finger. This is, I believe THE CULTIVATED TOUCH. 361 accurately represented in the accompanying engraving. In ex- aminations in the latter part of labor, when the os is dilated and the head low down, the finger may be used in almost any direction with equal ease. When the student examines in his first case of labor, he com- mences an education of the sense of touch, such as is neither FlO, no. Examination in the Stage of Dilatation,. necessary nor acquired in any other department of practice. In tactile examinations of other parts of the body, sight and touch, or sight, touch, and hearing, are combined ; but in the examin- ations of the accoucheur, touch is exercised without any assist- ance from the other senses. The obstetrician who has by long 'practice acquired the tactus eruditus in perfection may almost be said to have the end of his finger armed with an eye, and he reads the varied conditions of the internal parts which are within reach as accurately as the blind scholar reads the raised type in which books for the blind are printed. Although the forefinger of the right hand is that generally used, and which seems capable of acquiring the highest tactile education, it is well to accustom ourselves to all the other fingers, in case of being dis- 362 LENGTH OF NATURAL LABOR. abled in the right hand by any accident, or in case of some unusual shape of the pelvis or soft parts. We are commonly told to introduce the finger during a pain, and indeed the phrase, " Taking a pain," implies that we can at this time afford some assistance to the patient. Hence women more readily submit to examination when a pain is coming on than during the intervals. Formerly, when the principal object in making an examination was to ascertain the strength and efficiency of the uterine contractions, it was better to examine during a pain than at any other time. But since the mechanism of labor has been better understood, and we require to ascertain the exact position of the head during its progress, it is necessary to examine in the intervals as well as during the presence of pains. If we introduce the finger while the uterus is contracting, we should be careful not to rupture the membranes prematurely, as they are tense and thin at this time. The presence of the amni- otic bag, and, after the escape of the liquor amnii, the corruga- tion of the scalp, or increase in the caput succedaneum during the pains, prevent us from making out the relative position of the sutures as well as in the intervals between them. An examination, therefore, should always occupy a pain and part of an interval. Having ascertained the nature of the presentation, and the state of the parts within the vaginal canal, no other manual interference is required in natural cases, during the stage of dilatation, beyond an occasional examination, to ascertain the rate at which the labor is proceeding. We shall, however, be expected to give some idea as to the time when the delivery may be completed. A labor is considered natural as regards time when it does not exceed twenty-four hours from the commencement of the dilatation of the os uteri to the completion of delivery. Primiparous women frequently, however, exceed this period, and multiparous women are commonly delivered in a much shorter space of time. The full dilatation of the os uteri is consid- ered to occupy five or six hours, but in many cases it takes less, and in others more than this. The bony pelvis being normal and the pains natural, labor is quick in proportion as the os uteri and perinaeum are dilatable, and the vagina short and capacious; and tedious according to the rigidity of the os uteri and perinae- um and the length and contraction of the vagina. Sometimes one portion of the parturient canal is relaxed, and another con- RUPTURING THE MEMBRANES. 363 tracted; under these circumstances, one part of the labor will be rapid and the other slow and tedious. It is only by experi- ence, tact, and an appreciation of all the circumstances which modify the progress of labor, that anything like certainty of prognosis of its duration can be acquired. In parts previously rigid, the disposition to dilate may be suddenly manifested ; or the os uteri, after dilating favorably to a certain extent, may become immovable. As regards uterine contractions, we may have a sudden failure of active pains, or pains in cases which had been sluggish may become as suddenly energetic. It behooves, then, that the young practitioner should, as the rule, be guarded as an oracle in his vaticinations respecting the time of the termi- nation of labor in any given case. During the stage of propulsion, we may moderate and guide the pains by inducing the patient to cry out if the pains are excessively violent during the expiratory efforts, or to hold her breath, and add voluntary straining to the reflex actions of the respiratory^ muscles if the pains are feeble. In thus managing the open or closed state of the glottis, we can always increase or di- minish at will the force of the uterine and respiratory contrac- tions. As a rule, the membranes are ruptured spontaneously at the commencement of this stage. We should be especially care- ful not to rupture them before full dilatation of the os, if we can avoid it. When the stage of propulsion is fully formed, we may generally rupture the bag with advantage, if it has not occurred. This may be done with the nail of the forefinger during the height of a pain. When the membranes are tough, several ef- forts during successive pains are necessary before the membranes can be broken, but no violence should be used. Sometimes cases are met with in primipara in which the quantity of liquor amnii is so small, that it does not, from its bulk, interfere with the uterine action, and in which the labor goes on so satisfactorily, that it is advisable not to rupture the membranes until the peri- naeum is dilated and the head presents at the ostium vaginae. When the amount of fluid is large, it very much facilitates the progress of labor to evacuate it as soon as the os uteri is fully dilated. If the membranes are punctured, accidentally or inten- tionally, before the stage of dilatation is completed, it frequently happens that the os uteri, which had been dilating most favorably, becomes rigid and contracted, and labor is impeded for several 3(}.l DRAINING OFF OF THE LIQUOR AMNII. hours. On the other hand, cases are occasionally met with in which the os is dilatable but the uterus inactive, and in which dilatation may be promoted by the evacuation of the liquor amnii; but these are exceptions to the general rule. There is another point in the management of the liquor amnii worthy of notice. It sometimes happens that the head is well engaged in the pelvis before the liquor amnii begins to escape, and the proportions be- tween the head and the parturient canal are so exact, that no water flows away in the intervals between the pains, or during the greater part of the pains themselves. The head and canal act exactly as a ball-valve, and no fluid can pass except at the acme of a pain, when the force which should advance the head is expended in a slight dribbling of the waters. Much time is often lost in this way, and the best mode of obviating the diffi- culty is to drain off the liquor amnii through a small gum-elastic catheter passed up by the side of the head. Nausea and vomit- ing are always beneficial during the progress of labor. In the stage of dilatation they aid in dilating the os uteri by the mechan- ical straining which occurs, the reflex sympathy between the cardia and the os uteri, and the general relaxing effects of sickness. In the stages of propulsion and expulsion, also, they increase the expulsive efforts, and relax the vagina and perinseum. When the dilatation of the os uteri is very difficult, the mar- gin of the os being hard, thin, and painful, nauseating doses of tartar emetic are very useful. Sometimes, when the tenderness and spasmodic rigidity of the os uteri are very great, an opiate will be of great service ; or a moderate bleeding may be prac- tised when the patient is of plethoric habit. I have tried bella- donna, and a solution of atropine, in such cases, but without any good effects. During the stage of dilatation, and in the early part of the propulsive stage, the direction of the axis of the uterus should receive our attention. It should be as far as possible kept from anteversion, retroversion, or obliquity on either side, as these departures from its proper axis are certain to impede labor. From time to time, during every labor, the condition of the foetal heart should be ascertained. This can easily be done by means of a flexible stethoscope, and the knowledge thus acquired may become of great use in labors apparently the most uncom- HOW TO SUPPORT THE PERINEUM. 365 plicated. The accoucheur should never forget that in a case of labor two lives are under his care, and that both require his attention. In no point is the excellence of the Dublin school of midwifery more shown than in the care with which its best teachers advise that auscultation of the foetal heart should be practised during the progress of labor. The spirits of a lying-in woman should be kept up as much as possible, and this is best insured by cheerfulness and composure in those around her The lying-in room should not be crowded, and from time to time the accoucheur should retire, so that no constraint may be placed upon the bowels or bladder of the patient. She should be allowed very nearly her usual diet, if her stomach can bear it. In the stage of expulsion, the chief points are, the regulation of the expulsive forces, the direction of the head, and the pre- servation of the perinaeum. In the latter part of labor, the glottis is to the parturient function almost what the safety-valve is to the steam-engine. By opening the glottis, as by directing the patient to cry out ; or by closing it, as by directing her to hold her breath, we can, to a very great extent, regulate the expulsive efforts of the last and greatest stage of labor. Many conflicting opinions prevail as to the propriety of supporting the perinaeum. Some years ago I pointed out that pressure on the perinaeum excited reflex contractions of the uter- us—a point which is, I believe, now pretty generally recognized ; and I grounded upon this circumstance, and upon the facts that, in cases where pressure or support is most assiduously rendered, laceration sometimes occurs, while it rarely happens when wo^ men are delivered by themselves, an objection to the constant and sustained support to the perinaeum during the later part of labor. I believe that long-continued pressure tends to produce i the accident, by increasing the expulsive pains and by damaging J the perinaeum itself. We read of cases in which the perinaeum was supported for many hours in succession, which must always be unnecessary, since, if the pains are strong enough to threaten laceration, the expulsive stage could not last the time described. / My advice with regard to the perinaeum is, that the forefinger of the left hand should be kept upon the anterior margin of the perinaeum during the last pains, and the right upon the head, with a view to ascertain the moment when the perinaeum is dis- 366 SUPPORT OF THE PERINAEUM. tended to a dangerous extent with one hand, and at the same moment to retard the advance of the head with the other. The head should be pressed, in passing, close to the pubis, so as to strain the perinaeum as little as possible. If we prevent the rapid passage of the head, we do more to prevent laceration than can be accomplished by the most careful pressure. [When the woman lies upon the back, the support to the per- inaeum is made with ease to the attendant, and most advantage- ously to the patient, the palm of the right hand is placed on the perinaeum, the thumb being upon the right side of the vulva and the fingers upon the other. The pressure is made most naturally by the portion of the hand nearest the anus, and the head resting thus most conveniently' upon the palm acting as an inclined plane, passes between the thumb and forefinger, being thus guided, not restrained, by the support given. While many think lightly of the importance of support to the perinaeum, and perhaps over- estimate the dangers from its being illy performed, my practice and counsel is never to neglect it during the presence of pain, both for the actual benefit which may be afforded, and for as- suaging the sufferings of the mother. A noticeable relief from the extreme agony caused by the rapid dilatation of the perinaeum, is felt as the result of well directed support. The only cases of rupture of the perinaeum that have been brought to my notice, have occurred either when no physician was present at the birth, y or in conjunction with the use of instruments ; in one case where the double-curved forceps were introduced in a reversed position by an inebriated attendant.] The knowledge of the mechanism of labor is of importance, not only with reference to diagnosis and the use of instruments, but in the management of natural labor. Sometimes, the de- scent of the head through the pelvis is retarded by the imper- fect flexion of the head, or dip of the occiput. When the two fontanelles are on the same level, or nearly so, the occiput may be brought down by traction exerted with the finger on the ridge formed by the lambdoidal suture; by the use of the vectis or by upward pressure on the frontal or anterior portion of the parietal bones. Rotation of the head may be assisted by gentle pressure upon the occiput, or the portion of the parietal bone, next to the ischial planes upon which the head is descending. At the time of the exit of the head, its extension, or the separa- DANGEROUS EFFECT OF A ONE-SIDED PROVERB. 367 tion of the chin from the sternum, and the descent of the forehead and face over the sacral and perineal surfaces, may be aided by exerting slight pressure upwards upon the vertex, and traction downwards upon the frontal bone. As soon as the head is libe- rated, it should be ascertained if the cord be twisted round the neck, and the loop should as gently as possible be passed over the head in order to free the funis from pressure. [If this cannot be done and evident delay results from the tightly drawn cord, it may be cut by passing a probe-pointed scissors under it, care being taken not to wound the child, and the severed ends should be tied as speedily as possible. This frequently ends the labor and saves the child from the danger of death by asphyxia.] The rotation of the shoulders in the reverse direction to that taken by the face so as to bring the shoulders into the opposite oblique direction to that occupied by the head, may be aided by placing one hand upon the back of the neck, and the other upon the ster- num as the shoulders are passing. As the body of the child passes, it should be turned somewhat over the pubis. Those aids can only be afforded after a perfect knowledge of the mechanism of labor has been acquired, but they may then be made very considerably to facilitate the progress of delivery. The old axiom, "Meddlesome midwifery is bad," has had great force in obstetric practice, but it is, perhaps, better adapted to ignorance or partial knowledge, than to perfect comprehension of the mechanical and motor phenomena of natural labor. I have no doubt the time will come when these will be so well understood that the finger of the accoucheur will be in accord- ance with every change in the passage of the child during par- turition. Proverbs are always one-sided. The phrase quoted has, no doubt, been useful in preventing improper interference, but it has also a tendency to the prevention of interference when this is both useful and necessary. During the propulsive and expulsive stages it is usual for the patient to aid the respiratory efforts, by fixing her feet and pull- injr at a towel with the hands, or holding the hands of the nurse. And this exertion must be encouraged or discouraged, accord- ing to the power of the pains. [The advantage of the posi- tion upon the back is especially manifest in its convenience for bracing the feet and making voluntary exertion. Its inefficacy during the earlier stages of labor, before the os uteri is dilated, 368 How T0 TIE THE cord. should be remembered, and the patient not unnecessarily wea- ried by this inutile voluntary muscular effort.] When the head is passing through the vulva, the right knee should be raised so as to facilitate its passage. Throughout the whole of labor the woman derives comfort from pressure exerted by the hand of an attendant r>^r: the sacrum during the pains. I have not, on tf\ :>!:! ..■•, . m, said anything respecting the use of chloro- form :r L.bor, asl propose to devote a special lecture to •;•' ■■> ■■('.. . ' i ;t>stetric Anaesthesia. A ! he child,the umbilical cord requires to be tied. '"'"'■ should be formed of thread, doubled seve- ral t ^ -x^ip-wicking, bobbin, or tape.] It should be tied firmly about two inches and a half or three inches from the um- bilicus, and a second ligature should be applied at a little dis- tance from the first, towards the placenta. [It is the practice of the French hospitals, so far as I observed, and taught by Cazeaux, to cut the cord before applying the ligature. This is done about six or twelve inches from the child, and as soon as the section is made, holding the fcetal extremity between the thumb and finger to allow it to bleed a little, which has the double effect of reliev- ing the turgid vessels of their superabundant blood and giving the child a whiter appearance, more in accordance with the pre- vailing ideas of propriety and beauty. The second ligature is rarely applied. It is supposed that there is more danger of the child's being asphyxiated, than injured by haemorrhage.] Con- siderable force must be used in tying the cord, in cases of a large funis, from the deposition of an unusual quantity of the gelatin- ous matter constituting the bulk of the cord. Otherwise, the vessels may not be compressed, and bleeding may occur. In cases of large cord, it is always well to look at the funis a short time after the application of the ligatures and division of the funis, to see that no haemorrhage is going on. The second liga- ture is intended to prevent haemorrhage from the divided cord in cases where there are twins with a single placenta, or where the vessels of two cords inosculate, as they sometimes do. In dividing the cord, a pair of blunt-pointed scissors should be used, and the division should never take place under the bed- clothes, as the penis, or fingers, or toes have been sometimes in- jured during the separation of the funis. The hand of the ac- coucheur should now be placed upon the abdomen to ascertain HOW TO DELIVER THE PLACENTA. 369 the existence or non-existence of twin-pregnancy. After the expulsion of the placenta, the abdomen should be again examined, to learn whether the uterus is contracted. It ought to be felt above the pubis, or at the pelvic brim, of the shape, and almost the hardness, of a cricket-ball. As soon as the child is born, the first attempts at respiration usually occur immediately, the first inspiratory movements being excited as a reflex action by the influence of cold upon the sur- face. The diaphragm is the special muscle of inspiration, and this is the first to act in the establishment of respiration in the new-born infant, as it is the last to relinquish its functions in a case of death from asphyxia. A short period of repose follows upon the birth of the child, but in the course of a few minutes uterine contractions are again felt. The placenta may have been detached by the pains which effected the delivery of the head and trunk, or it may now be separated from the uterus. When the pains recur at the time mentioned, gentle traction should be exerted upon the cord, the hand of the nurse being placed upon the abdomen, and exerting gentle downward pressure. If there should be no pain, the fin- ger should be introduced into the vagina, and the stringy inser- tion of the cord into the placenta will generally be felt ; or, if not, the fundus uteri should be irritated by the hand externally, so as to cause contraction. In extracting the placenta, slow and gentle traction only should be used, as by this means the whole of the membranes, and any coagula which may have formed, are likely to come away with the placenta. The cord should be drawn downwards by the left hand, the fore-finger of the right being placed upon the insertion of the cord, as it is here that laceration occurs, when it gives way. Of course, if the cord is breaking, the traction should cease, and the placenta ought to be drawn forth by the fingers. [As soon as any resistance is felt, he ought to slip up two or three fingers of the other hand, along the upper surface of the cord, as far as the os uteri; the points of these fingers which are intended to press the cord backwards, are brought together so as to receive the latter in the entering angle thereby formed, around which it plays like a pulley. To understand the advantage of this manoeuvre it is only necessary to bear in mind that the tractions made by one hand alone would correspond to the axis 24 370 MECHANISM OF PLACENTAL DELIVERY. of the vagina, which forms an angle with that of the uterus ; whence it happens that the placenta, instead of being drawn towards the centre of the orifice it has to traverse, would abut against its anterior border, and the corresponding parts of the cervix, upon which all the tractive efforts are spent. The patient should be directed to bear down while the tractions are made. As the placenta closes the orifice, and gets into the excavation, the operator changes the line of traction and gradually carries the cord forward, so as to make it always Correspond with the axis of the pelvic canal. Under this joint influence, the placenta soon reaches the vulva, where it is seized by the thumb and fin- gers and twisted round several times, so as to complete the de- tachment of the membranes and form them into a solid cord, for the double purpose of preventing their laceration and of secur- ing their entire removal.—Cazeaux.] As a rule, the placenta should be examined, to be sure that no portion of it remains in utero. After the delivery of the placenta, a bandage should be applied to the abdomen, with a view to gentle compression of the uterus and the support of the vascular system of the mother, after the tension of the abdomen during pregnancy. No doubt, by forcible compression after parturition, injury may be done to the uterus ; but I have known cases of mortal fainting occur in cases where no other cause of death could be assigned than the neglect of bandaging. I therefore recommend it. [The bandage, or roller, applied generally after labor, is very often productive of more injury than benefit. In cases of severe flooding, it is generally inadmissible, and for the simple reason that it is in the way. Its presence prevents the manipulation HOW TO, AND WHY PUT ON A BANDAGE. 371 of the abdomen, the application of ice, the douche, etc., and prevents the attendant from obtaining the very important infor- mation of the presence or absence of uterine contractions. There are some who hasten to put on the bandage after delivery, as if the life of the patient depended upon it. Nature puts no bandage upon the cow, or the sheep, and in the Lying-in Hos- pitals of Paris, the midwives put none on the women. The cows and sheep have no haemorrhage, and out of some seven hundred women that I saw confined at l'Hopital des Cliniques, under the charge of Dubois, I did not see one solitary case of flooding. A woman after confinement needs a bandage just as much as, or rather upon the same principles that guide its use, in case of tapping for ascites. After all danger of haemorrhage is passed, a bandage may be applied for support to the abdomen. When properly done, it should be about half a yard wide, and applied much lower down than usual; the first pin should be placed at the lowest border, near the commencement of the up- per third of the thigh. Over the uterus the pressure should not be great, but tighter above it, so that the result is, that the uter- us is rather pressed down than upon. Sometimes it is desirable to place a pad under the bandage (and nothing is better than a rolled up pair of long woollen stockings), but this should not be upon the uterus, but above it, so as to prevent the uterus from expanding, while at the same time it affords some pressure upon the descending aorta, imme- diately before its bifurcation.] When the bandage has been applied, the mother is allowed to rest while the child is being dressed, when she is made comfort- able by the nurse. The child should be put to the breast within a few hours after delivery, but should not suck frequently until the secretion of milk is established, otherwise the mother suffers more than is necessary from after-pains, particularly in multi- parous cases. The child may, from a variety of causes, be born in a state of Congenital Asphyxia, in which instant and energetic efforts become necessary for its restoration. The chief causes of this condition are such a continuous contraction of the uterus during labor as to interfere with the due supply of blood to the maternal side of the placenta, partial or entire placental detach- 372 SIGNS OF CONGENITAL ASPHYXIA. ment before the time of birth, and continued pressure upon the umbilical cord. The child may also be asphyxiated by being born, in the absence of the attendants, enveloped in the mem- branes, or " Caul," so as to render respiration impossible. The signs of congenital asphyxia are failure of the foetal pulse, and spasmodic movements of the presenting part of the child occurring for some time before death at tolerably regular inter- vals. When the child is born asphyxiated, the surface is very dark, from the injection of the capillaries with venous blood. It becomes necessary to understand the nature of the intermittent spasmodic movements just mentioned, with a view to treatment. When the blood of the foetus becomes entirely venous, it stimu- lates the medulla oblongata, as proved by the experiments of Schneider, Yolkman, and others, so as to produce gasping efforts of a respiratory character. These movements are termed Cen- tric, to distinguish them from the Eccentric or Reflex move- ments, dependent on external stimuli. They occur in utero, in precisely the same way as when the foetus is exposed to the ex- ternal air. The first movements of children who are born in a state of asphyxia, and who are recoverable, are of this kind, and these centric movements wTill sometimes of themselves slowly estab- lish healthy respiration, the intervals between the gasping efforts becoming smaller, and the movements themselves be- coming changed into the ordinary reflex respiratory movements. It is seldom that a child can be restored after the cessation of these centric movements, notwithstanding that the heart will frequently beat for some time after they have ceased. The younger the foetus, the longer is the time occupied in the act of dying, and the greater the chance of resuscitation. The ordinary means of establishing Respiration in cases of partial asphyxia consist of sprinkling cold water on the face or chest of the new-born child; slapping it on the sides or breech ; pinching the ears, or irritating the eyelids or anus; rubbing the nares and mouth with a little brandy or sal volatile. If the child is very black, a small quantity of blood should be allowed to flow from the umbilicus before tying the cord. In more serious cases, or when the above means are not sufficient, the child is generally put in a bath of about the temperature of the blood, or wrapt in warm flannel and kept near a fire. Alter- HOW TO EFFECT ARTIFICIAL RESPIRATION. 373 nating with this raised temperature, the child should be sprinkled with cold water, and the limbs and body of the child rubbed assiduously with brandy or spirit. Great care should be taken, in all cases of asphyxia in new-born infants, to cleanse the mouth, nares, and fauces. Artificial respiration may be practised, either from mouth to mouth, or by means of a tube inserted into the mouth or nostril. During these operations the thorax should be alternately squeezed by the hand, and allowed to relax. Artificial respiration is not, however, of so much value in congenital as in other forms of asphyxia, from the fact that the foetal lung has never been distended with air. The plan suggested by Dr. Marshall Hall has excited much attention of late, and is said to have been successful in a great number of instances. If it should prove efficacious in cases otherwise irrecoverable it will become an invaluable boon. Dr. Hall's method consists in placing the foetus on its face, with the fore- head raised, and rotating it from side to side, so as to induce movements similar to those of natural respiration, and to favor the escape of mucus from the air-passages. These movements should be combined with continuous frictions of the limbs, so as to keep up the circulation as well as possible in the absence of respiration. In cases of congenital asphyxia, when the child has been' recovered, the child should be watched carefully during the first twenty-four hours of life, as there is a tendency to the occurrence of what has been termed secondary asphyxia; and the child will frequently be observed to change color from imperfect oxygenation of the blood. Frictions, and the free ex- posure of the child to the air, are the best means of preventing this accident. Dr. Hall is opposed to the use of the warm bath in resuscitation from asphyxia, on the ground that it pro- duces faintness and exhausts the remaining powers of life. LECTURE XXV. MANAGEMENT OF THE PUERPERAL STATE. Gentlemen :—In the puerperal state, the patient has to recov- er from the shock of labor itself, and to pass through the disordered conditions incident to the state of the uterine cavity and the walls of the uterus after parturition, and to the establish- ment of mammary secretion. The influence of the shock of labor is visible in the lowered state of the pulse which obtains some hours after labor, the debility felt by the patient, and the intolerance of light, noise, and other stimuli previously borne with ease. The shock itself depends on the exhaustion of the nervous system by the pro- longed muscular efforts, the physical pain, the loss of blood during the separation and expulsion of the placenta, and the removal of the pressure exerted by the gravid uterus during the latter months upon the organs of the body. The influerice of the shock of parturition is best relieved by an opiate when the labor has been severe, or natural sleep, quiet, a darkened room, and the prevention of all excitement as far as possible. If the patient be greatly exhausted by labor, a little stimulus may be administered after delivery; but with this exception, nothing but gruel, tea [panada], and similar matters should be allowed during the first twelve hours. After the completion of labor, the most important considei- ations respecting the child-bed patient, are those which relate to the internal surface of the uterus. When describing the gravid uterus, I dwelt upon the involution of the muscular structure of the organ after parturition, by the degeneration, disintegration, and removal of the large muscular fibres, and the substitution in their place of the rudimentary cell-fibres proper to the uterus in the unimpregnated state, so that it is not in this place neces- sary to refer further to the post-partum changes in the parietes of the organ. 8T4 CONDITION OF THE UTERUS AFTER DELIVERY. 375 If the portion of the internal surface of the uterus be examined within a few days after labor, it is found to be raised somewhat above the other parts of the uterus, because of the increased thickness of the organ in this situation, and the remains of the decidua serotina. The open mouths of the veins are still visible, and small pieces of coagula are hanging from them into the cavity of the uterus. Since the time of Harvey, who was one of the earliest to make the comparison, the state of this part of the uterus after parturition has often been likened to a stump after amputation, or a new-made wound. The comparison is only correct to a limited extent. The small, curling arteries and the veins of the uterus have certainly been divided in the sepa- ration of the placenta, but, except at these points, no structural lesion occurs. The portions of the internal surface between the arteries and veins are occupied by the remains of the decidua serotina, or that part of the developed uterine mucous membrane lying between the uterine parietes and the placenta. There is no formation of pus upon the surface from which the placenta has been removed, as in the healing of an ordinary wound. The portions of coagula hanging from the venous openings separate and are discharged, or remain to plug up the vessels, and the veins and arteries close by a process of gradual contraction and obliteration, under the influence of the contracted uterus and the diminished supply of blood to the organ. What I mean to say is, that there is no evidence in healthy cases of any inflammatory action or suppuration at the placental site during the return of the uterus to the size of the unimpregnated state. Besides the coagula hanging from the mouths of the veins, coa- gula probably exist to some extent, in almost all cases, within the cavity of the uterus, as the remains of the blood poured out during the act of the separation of the placenta or immediately afterwards. Having thus described the condition of that part of the internal surface of the uterus from which the placenta has been separated, we are now in a position to speak of the Lochia—a sanguinolent discharge from the vagina, which con- tinues after labor for a time, varying from three or four days to a month, but which generally diminishes or disappears about ten or fifteen days after delivery. The lochial discharge consists of sanguineous matter derived from the surface of the uterus at that portion to which the pla- 376 SIMILARITY OF THE MENSTRUAL AND LOCHIAL FLUX. centa has been attached, and of sanguineous debris formed in the breaking down and discharge of the whole of the uterine deci- dua. The breaking down of the small coagula from the mouths of the uterine veins, and coagula found in the cavity of the uterus, furnish some of the discharge, but the greatest part is furnished from the decidual lining of the cavity of the body of the uterus. From the evidence of numerous preparations and specimens which I have examined, I am convinced that the whole of the decidua which does not come away with the pla- centa, loses its vitality, becomes broken down, and is discharged during the first week or two of the puerperal period. I have seen the whole of the internal surface of the uterus covered with the bloody exudation thus formed, and the uterus may be found in every stage of progress of throwing off the decidua, from the perfectly smooth internal uterus, from which the whole of the decidua has been detached, and the organ studded with patches of decidua, or completely covered with this membrane. I look upon this exfoliative shedding of the mucous membrane or uterine decidua, as in many respects analogous to the change which takes place in the uterine mucous membrane at the cata- menial periods, and the lochial and menstrual discharges appear to be essentially the same, except that the lochial flow is more profuse than the menstrual. In animals, there is no lochial dis- charge, because the placental cotyledons, or that portion of the placenta which fulfills the function of the decidua in the human subject, are permanent. No doubt the basement or germinal portion of the uterine mucous membrane remains both after the catamenia and the lochia, and gives size to the formation of the new mucous membrane found after menstruation and parturition. The lochial discharge is found to possess a peculiar smell. At first it is of the color of pure blood, mixed occasionally with coagula. It is discharged with the greatest readiness during the time of micturition and defecation, or while the uterus is con- tracting, as in after-pains. After a few days, the sanguineous character of the discharge diminishes, the flow becoming greenish and frequently having a disagreeable smell. It is now called the " green waters," and the next change is to a whitish secretion, which gradually ceases. The green color is caused by the chemical action of the utero-vaginal secretions upon the diminished amount of blood globules now present in the dis- charge. RELIEF OF AFTER-PAINS. 377 It is of importance that the lochial discharge should be free. In the event of deficiency, friction of the abdomen should be practised", with a view to excite contraction of the uterus and the expulsion of any collections in its cavity. Warm water, or infusion of camomile flowers, should be injected into the vagina two or three times daily, and in cases where any mischief is apprehended, the cavity of the uterus itself may be washed out. After delivery, a warm napkin should be applied to the vulva. Napkins are worn during the whole continuance of the lochial flow, and the nurse should change them frequently. The change of the napkin promotes the lochial flow, besides being necessary to cleanliness, as the uterine discharges very speedily decompose, and become intensely disagreeable. I have some- times been obliged to order a bag of animal charcoal, or a piece of prepared charcoal sheeting, to be placed in the bed to neu- tralize the lochial effluvium. The After-Pains are the natural attendants upon the uterine contractions which occur after parturition. The uterus is usu- ally felt in a state of persistent contraction; but from time to time this contraction is increased, and is attended by pain. After-pains increase in severity with every labor; so that pri- miparous women suffer little from this cause, while multiparous women are troubled with them in proportion to the number of children they have borne. They commence soon after labor, and in the worst cases last three or four days, being produced spontaneously, or by any reflex irritation, such as the draught in the mammae, the sucking of the child, taking food or drink into the stomach, and the action of the bowels or bladder. Within certain limits, these pains are very salutary, tending to the expulsion of irritating materials from the uterus and the perfect involution of the organ, as the reduction of the organ to its pro- per size is called. Sometimes they occur violently immediately after the completion of delivery, when the finger should be passed into the vagina, and the os uteri examined, with a view to the removal of any coagula which may remain in the uterus and vagina. When no retention exists, but the pains are neural- gic in character, an opiate, and a warm linseed-meal poultice upon which a little laudanum has been sprinkled, applied to the abdomen, afford great relief. I have sometimes found that an anodyne embrocation applied to the breasts is of service in relieving distressing after-pains. The sources of uterine irrita- 37S WHEN IS THE SECRETION OF MILK? tion should be avoided at much as possible. When slow and long-continued, after-pains can never be neglected with impu- nity, as they sometimes run on to inflammatory disorder. In most women there is some appearance of Milk in the breasts before the coming on of labor. The areola acquires its deepest shade during and immediately after parturition, and at this time, in women of dark hair and complexion, an almost black zone surrounds the nipple. There is sometimes a pretty free secretion of-milk from the beginning, but it is generally the third day before the secretion is fully established. The mam- mary secretion is, probably, dependent upon the internal condi- tion of the uterus already described, being excited as a reflex phenomenon by uterine irritation. The breasts in turn excite the uterus, and these organs mutually contribute to the return of the uterus to the unimpregnated condition, and to the establishment of the mammary secretion. When the milk is first secreted in quantity, there is a great determination of blood to the glands, producing considerable heat, pain, and swelling, which last for two or three days in favorable cases. The mammae often become greatly distended, not only from the secretion and reten- tion of milk, but from tumefaction of the gland itself. The milk first secreted, termed the colostrum, i3 more irritating than that subsequently formed, and acts as a natural aperient, clearing the bowels of the child from the remains of the meconium or the TREATMENT OF THE BREASTS. 379 secretions accumulated in the intestines during fcetal life. Some- times women suffer considerable pain from the mere weight of their breasts, in which case they require to be supported by a bandage placed round the neck. As soon as the milk is secreted plentifully, the child should be often put to the breasts, and they should besides, be drawn, if necessary, by the nurse, so as to prevent accumulations of milk in the ampullae, or the galacto- pherous ducts. Frequent frictions with olive oil [still better castor oil] or a mild camphorated liniment, are also very useful, as favoring the flow of milk through the tubes, and diminishing the tumefaction of the glandular lobules. If the breasts are very hot and painful, an evaporating lotion should be applied constantly. [The difficulty which many experience in making applications to the breast which will not be displaced, by turning, induce me to add here the figures on this and the preceding page.] The nipple should always be wiped care- fully after each drawing of the breast, or the sucking of the infant. As regards the frequency of application of the child to the breasts, a certain amount of caution should be observed. If there be a profuse secretion, and the glands are not relieved, inflammation and suppuration occur; if the child should be applied too frequently, the secretion is greatly increased, as each act of sucking is at once a relief and a stim- ulus to the gland, and the patient may be weakened by galac- torrhoea. Again, if the glands are swollen, but without any 380 PAINFUL AFFECTIONS OF THE NIPPLE. great secretion of milk, and the child is constantly applied, great pain is produced, and the tubes and glandules may become actually inflamed, and suppurate from this cause. Mammary abscess during the puerperal month may arise from three causes:—1, the irritation of sore nipples ; 2, the distension of the gland, or some portion of its substance and tubes ; or 3, the irritation of a feebly secreting gland, by constant attempts at suckling the child. When we desire to diminish the quantity of milk, I generally give sulphate of magnesia, with or without dilute sulphuric acid, so as to keep up a moderately free action of the bowels, and have the breast relieved by frequent frictions, resorting to drawing or suckling as little as possible. These means, with in some cases a diuretic, and restrictions as regards diet and drink, I have never known to fail. When we desire to increase the secretion of milk, warm fomentations, and the application of the leaves of the castor-oil plant, with fomenta- tions by the water in which they have been boiled : or the use of a castor-oil embrocation, after fomentations with plain water, are very efficacious. [I have found painful affections of the nipple to be the most frequent cause of broken breast, the mother feeling it almost impossible to nurse the child, thus allowing an accumulation of milk, which ultimately produces abscess. The nipple should be hardened by daily frictions for many weeks before the expected time of parturition, using borax and brandy, Epsom salts dis- solved in water and other astringent washes. If the nipple be cracked and fissured, I have noted more benefit than from any other source, by washing them with a weak lead wash, followed by a poultice. The recently much vaunted collodion, which forms a pellicle over the crack, being drawn off by every nursing greatly aggravates the ill. When there is no fissure or abrasion there is sometimes excessive sensibility of the nipple, which is much benefited by bathing with tincture of myrrh and rose water in equal parts. Sometimes a piece of cotton, moistened in wine of opium, applied a half hour before nursing—the nip- ple afterwards, in this as after all applications, being carefully washed with castile soap and water—much mitigates the suffer- ing. The tincture of benzoin hardens the nipple and will be found occasionally of great service. If the end of the nipple is cracked (seemingly filled with proud flesh, resembling papillae, A CAUSE OF PUERPERAL MANIA. 381 scarcely noticeable until drawn out by the sucking of the infant, and excessively sensitive), touching them down to the bottom with a sharpened point of nitrate of silver, will often be followed by a change of action and speedy recovery.] The state of the breasts incident to the establishment of the milk, and the condition of the internal surface of the uterus, often produce a considerable amount of constitutional irritation and fever, known as Milk Fever, Ephemera, or Weed. This is attended by slight shivering, followed by a quick pulse,' and is generally relieved by the full secretion of milk and free per- spiration. It seldom requires any other treatment than careful management of the breasts, attention to the lochial secretion, and the use of saline aperients and diuretics. It seldom or never lasts more than two or three days, unless it runs on to more serious disorders of mammary abscess, which we shall have hereafter to consider. The Diet of the puerperal woman is an element of much importance. Up to the time of the establishment of the full secretion of milk, the tolerably free action of the bowels, and the subsidence of the febrile reaction which commonly occurs at the lacteal crisis, the diet should be moderate in quantity and unstimulating. No animal food should be taken, as the rule, up to this period. Cases sometimes occur in which the exhaustion is so great that animal food and stimulus are required from the first. After this time, feeding may begin, and a generous diet gradually introduced. It must be remembered, that the patient has to recover from the long drain which pregnancy is in itself, and to prepare for the drain of lactation. The secretions and excretions being .carefully regulated, women may live well after the first few days from the date of labor. The constitu- tion has to get rid of old material, and to repair losses. These indications are best fulfilled by excretion and nutrition. Many women make bad nurses, suffer unduly from lactation, and become nervous and irritable, from being under-fed during the puerperal period. Most of the cases of puerperal mania which I have seen, have resulted from exhaustion produced during the first two or three weeks after labor. Rest, especially in the early part of the puerperal state, is of great moment. Those who get up too early, suffer from haemor- rhage and prolonged lochial discharge, owing to the absence of 3S2 VALVES IN THE UTERINB VEINS. valves in the uterine veins [the presence of valves in the uterine sinuses, resembling in shape the ileo-coecal valves, was demon- strated to the New York Academy of Medicine April 15, 1857, by Prof. Alonzo Clark, and the reason of this subsequent haemor- rhage was attributed to their being dragged open after closure by the subsequent enlargement of the uterus], and the momen- tum of the blood downwards. They are also liable to prolapsus from the weight of the uterus, and the relaxation of the uterine ligaments, and the soft parts of the pelvis generally. With res- pect to the poor, no absolute limit can be placed because of their urgent necessities; but, when it can be done, the patient should remain ten days in the horizontal position, and, after that time, should rest during a portion of the day, until the end of the month. After parturition, it is natural for the Bowels to be consti- pated. This, in part, arises from the exhaustion induced by labor in all the organs under the influence of the spinal cord, and, in part, from the small quantity of food usually taken within the first two or three days of the puerperal period. Left to themselves, the bowels would probably pass a week or ten days in a state of inactivity. It is usual and proper to give a mild aperient dose on the third day after the labor, and the medicine in most common use for this purpose is castor oil; a seidiitz powder, or a draught of sulphate and carbonate of magnesia, in mint-water, will generally suit when castor oil cannot be taken. The idiosyncrasy of the patient should, be con- sulted upon this point, and any aperient avoided which is likely to cause gastro-intestinal irritation. On paying our first visit to a lying-in patient, which should always, if possible, be within twelve hours of her delivery, one of our questions should be with respect the State of the Bladder. In long and painful labors, especially in primipara, it not unfrequently occurs that the bladder is quite paralyzed to the influence of volition, and the patient finds herself unable to pass urine. The paralysis appears to depend on the pressure exerted upon the neck of the bladder by the fcetal head, and to affect the sphincter vesicae chiefly. The effects of pressure are probably aided by the influence of the shock of labor upon the lower part of the spinal marrow. The difficulty generally dis- appears spontaneously after a few days, the bladder recovering its tone and irritability. Sometimes a little urine is passed, but ORDINARY CARE AFTER DELIVERY. 383 the bladder is unable to empty itself thoroughly. Besides ask- ing the question, it is proper, if there should be any doubt upon the subject, to place the hand upon the hypogastrium, when, if the bladder be distended, its elongated oval outline is readily felt above the pubis. The remedy is the use of the catheter for a few days. It is of great importance to diagnose this affection, as a distended bladder may be mistaken for other diseases, and the patient put through a course of inapplicable treatment; or the organ may be ruptured, and lead to a fatal result. The quantity of foetid ammoniacal urine drawn off in some of these cases is quite astonishing. [The self-retaining catheter of Dr. Sims will be found of great utility where there is temporary paralysis of the bladder, parti- cularly if the patient, as often in thinly populated places, cannot be visited frequently by the physician. Especially if there be cause to suspect any injury of the bladder from pressure, the use of the instrument here delineated, will cause it to be constantly contracted, and may thus avert a threatening fistula which might occur if the bladder was allowed to remain distended.] It is necessary to say a few words respecting the manage- ment of the Infant during the puerperal period. After delivery, it is expected that the accoucheur should make such an examination of the child as will enable him to say that the infant is perfect and well-formed. The state of the genital organs, the hands and feet, and the mouth and oral cavity, should be observed. At our first visit, we should inquire whe- ther the child's bowels have been relieved or not, and whether it has passed urine. The bowels are generally purged by the 381 HEMORRHAGE FROM THE FUNIS. irritation of the meconium and the effects of cold upon the sur- face. If the bowels have not been moved, or the evacuations are insufficient, a teaspoonful of castor oil should be given. In cases of retention of urine, the bladder can generally be made to act by sprinkling a little cold water upon the hypogastrium, by applying a hot sponge to the genitals, or by the use of a warm bath. Sometimes the phymosis natural to the male infant is so great as to interfere with the flow of uriue, or micturition is always attended by pain. In these cases, relief is obtained by dilating the aperture of the prepuce by a probe. The child is generally kept in the same room as its mother, and the sub- dued light proper to the lying-in woman is well suited to the delicate eyes of the child. The management of the Funis is usually very simple. It is wrapped in a piece of singed linen by the nurse, and the pro- jecting portion dies and falls from the umbilicus within a week after delivery. The stump heals spontaneously: and after a time the navel is drawn in by the action of the urachus, and the remains of the vessels passing from the umbilicus to the liver. Sometimes the site of separation becomes sore, large granula- tions sprouting from its surface, requiring the application of sulphate of copper, or some other astringent. In some cases these florid growths have required removal by the scissors. Haemorrhage has in rare instances occurred from the stump of the funis, requiring ice, astringents, and pressure for its relief; and it has happened that children have been lost from this form of bleeding. [An elaborate and interesting paper on this sub- ject is in course of preparation by my friend Dr. J. Foster Jenkins, now of Yonkers, N. Y., by the appointment of the American Medical Association.] Traumatic tetanus from the division of the funis is rare in this country, but it is a disease of not infre- quent occurrence in hot climates, as the East and West Indies; and it occurs in other localities, as in the Faro Islands, where ventilation and cleanliness are greatly neglected. A few days after labor, it is very common for the child to be affected with Jaundice. This arises from the great change effected in the circulation of the liver by the establishment of respiration and the arrest of the current of blood between the funis and the liver. This form of jaundice disappears as the liver becomes accustomed to the conditions of extra-uterine life FOOD FOR THE CHILD. 385 and the flow of bile is established. When it does not pass off readily, a dose or two of grey powder, and a little castor oil, are sufficient to cure it. It is hardly necessary to insist upon the Breast Milk as the natural food of the infant, yet an enormous number of child- ren die anually, within a few weeks after birth, of marasmus caused by want of breast-milk. The medical attendant should invariably contend for the suckling of the child, or the engage- ment of a healthy wet-nurse. This should be arranged as early as convenient, as much injury is sometimes done in a short time to the tender stomach of the child by attempts at artificial feed- ing. Pathological inquiries show that the gastric mucous mem- brane has a tendency to soften under a deprivation of proper nourishment, and this softening is attended by marasmus and fever, ending in death. When artificial feeding is inevitable, the child will have the best chance of life from the use of fluid food only. Asses' milk or cows' milk, diluted at first with an equal quantity of water and sweetened with sugar, the quantity of water being diminished as the child becomes older, form the best infantile nourishment under these circumstances. The milk should always be fresh, and some experienced nurses greatly prefer boiled milk for children. Many of the matters treated of in the present and the preced- ing Lecture may be thought to pertain to the nature of " com- mon things ;" but attention is not the less necessary to them, if we would conduct patients safely through parturition, and the puer- peral state in natural cases. It should always be borne in mind, that at any stage of the processes through which the patient passes between the commencement of labor and puerperal con- valescence, the most simple case may be converted into one of difficulty and danger. 25 LECTURE XXYI. PRESENTATION OF THE FACE. Gentlemen :—In the preceding Lectures we have treated of the mechanism and management of cases in which the head presents in its different positions. We have now to pass from cranial presentations to those of the face. The transition from vertex to face presentations is easy and natural, because of the identity of the parts concerned. It will be found con- venient to direct attention to the following considerations in connection with presentations of the face—namely, the mechan- ism, the diagnosis, and the management. There is a very close analogy between the mechanism of face and vertex presentations. Let the fronto-mental diameter of the fcetal head be substituted for the occipito-frontal at the brim of the pelvis, and the similarity as well as the difference will be readily appreciated. It will be fresh in your memories that three kinds of obliquity were spoken of in the passage of the head through the pelvis in vertex cases: 1. An obliquity con- sisting of the position of the long axis of the fcetal head in one of the oblique diameters of the brim. 2. An obliquity, consist- ing of a dip of the posterior extremity of this axis in the cavity of the pelvis. 3. An obliquity, consisting of a dip of one or other extremity of the bi-parietal diameter of the cranium in the pelvic basin. A similar triple bias, or obliquity, obtains in face presentations. Thus the fronto-mental diameter of the face, which represents the occipito-frontal of the head, in vertex cases, is oblique as regards the diameters of the brim, and oblique as regards the superior plane of the pelvis, while there is a dip of the anterior extremity of the bi-temporal diameter of the face, in the pelvis, corresponding to the dip of the bi- parietal diameter of the head in vertex cases. The chief defect in the analogy of face and vertex presentations is, that while in 8S6 PKCULIARITIF.S OF FACE PRESENTATIONS. 387 the latter the posterior extremity of the long diameter of the head is from first to last lowest in the pelvis, in the former there is a change effected, the frontal end of the fronto-mental diame- ter being lowest at the commencement, and the mental extrem- ity lowest at the end of labor. This defect is, however, more apparent than real, because the face rotates so much in the pel- vis as to make the chin represent the occiput in the act of the disengagement of the head. In addition to the parallelism already mentioned, there are certain linear guides to the posi- tion of the face which in a manner represent the sutures of the cranium. Thus the mouth may be said to replace the anterior fontanelle at the commencement of labor. The bridge of the nose corresponds to the sagittal suture; and the ridges of the orbits to the coronal or lambdoidal sutures, as the case may be. The grand difference between vertex and face cases is, that in the former the head is flexed—that is to say, the chin is bent down upon the breast, the occipital extremity of the head thus becoming the most advanced or depending portion of the cranium ; while, in face presentations, the head is extended, the chin being separated from the chest as far as possible, and the head thrown back on the nape of the neck. Now, it is obvious that there may be many intermediate positions between extreme flexion and extreme extension; but, as a general rule, one or other of these extremes does actually obtain, and semi-extension is of rare occurrence. When it does exist, brow presentations are produced, and they are amongst the most difficult of cranial labors. Extension of the head increases as labor advances, so that when the head is in the act of disengagement, the chin is further separated from the breast than at any other period of labor. The manner in which such a decided irregularity as the extension which produces face presentations is brought about, is somewhat obscure; but we are in possession of some physiolo- gical facts and principles which will account, to a certain extent, for a portion of these, as well as of other forms of mal-presenta- tion. Before, however, going on to state these, it is interesting to remark, that flexion is the normal condition of the foetus— every limb, every finger, the trunk, and, in fact, every movable member is flexed, and the extension of the head, in face cases, must, therefore, clearly be the result either of unusual mechani- cal or vital conditions, intrinsic or extrinsic to the foetus. The 388 CAUSE OF FACE AND MAL-POSITIONS. application of the foregoing and following considerations extends, it should be said, not merely to face presentations, but to mal- positions in general. Dr. Fleetwood Churchill and Dr. Simp- son arrange the causes of mal-presentations pretty nearly as follows: 1. Face presentations and mal-positions generally, are the result occasionally of premature labor, in which the moulding influence of the shape and contractions of the immature uterus and the reflex contraction of the limbs of the foetus, are not effective. 2. They are the result of death of the foetus in utero; or, in other words, of loss of muscular tone and the adaptive reflex movements, and an alteration of the specific gravity of the foetal head. 3. They are the consequences of the application of unusual excito-motor stimuli to the foetus and uterus. 4. They are the result of causes mechanically displacing the whole foetus, or the presenting part, at the commencement of labor. With regard to these statements it may be remarked, that in cases of premature labor it is doubtful whether the excito-motor functions are so well-developed as to determine the position of the foetus in utero, while the small size of the foetus must to a certain extent abrogate those mechanical relations upon which the application of normal stimuli depend. With regard to death of the foetus in utero, it is right to state, that although the absence of reflex motions may have a share in producing abnor- mal presentations, yet there is reason to doubt whether a mere physical explanation may not suffice for a certain portion of them. I have on a former occasion referred to some very inter- esting papers, by Dr. Matthews Duncan, of Edinburgh, on this subject. If normal stimuli determine the natural presentation, abnormal stimuli must of course be admitted as the efficient causes of some errors of presentation; but to analyze the exact nature of such cases, and to determine how and when they are produced, is out of our power; their history must, in fact, be a matter of pure conjecture. The fourth series of causes mentioned are more within the scope of actual observation, and may some- times be traced with considerable accuracy: thus, a vertex pre- sentation may obtain before the fcetal head has become eno-a«-ed FREQUENCY OF FACE PRESENTATIONS. 389 in the inlet of the pelvis, and it may be altered by premature and sudden rupture of the membranes, especially if the quantity/ of liquor amnii be unusually great. Thus much in relation to face presentations generally; let us now trace the mechanism, in each variety, from the commencement to the termination of labor. There are four presentations of the face, as of the vertex, and they are similarly numbered. In the first, the forehead is to- wards the left acetabulum; in the second, towards the right acetabulum ; in the third, towards the right sacro-iliac synchon- drosis ; and in the fourth, towards the left sacro-iliac synchon- drosis. These positions are the exact analogues of the four vertex presentations respectively, and may be looked upon as vertex cases in which the head has become accidentally extended. In practice, it will be found that the third and fourth face pre- sentations are so extremely, rare as hardly to be worth enumer- ating, and consequently our attention may be confined to the first and second only. The first is the most frequent, being to the second, according to Naegele, as twenty-two to seventeen. As regards the frequency of face-presentations, Dr. Fleetwood Churchill has collated the proportion in nearly a quarter of a million of cases, and he finds that this mal-presentation occurs once in about 231f cases. In the First Facial Position, if the finger be introduced into the os uteri at the commencement of labor, it will impinge upon the bridge of the nose ; carrying the finger forwards and to the left, it arrives at the forehead, which is found oppo- site the left acetabulum ; and just beyond the root of the nose the frontal suture may be traced upwards and forwards, widen- ing in its course towards the great fontanelle. This opening can, however, seldom be reached ; and, indeed, the farther out of reach it is, the more favorable is the position of the head. Tracing the nose backwards and to the right, the mouth is reached, and the alveolar ridges may be distinguished. Still further backwards, the chin may be found in relation with the right sacro-iliac synchondrosis. The line represented by the bridge of the nose does not, however, cut the os uteri equally, it is more posterior than anterior, and consequently the right side of the face occupies the anterior and greater segment of the mouth of the uterus. The primary caput succedaneum will in 390 MECHANISM OF FACE PRESENTATIONS. this presentation be found upon the upper half of the right side of the face, and will include a surface corresponding to the Fig. ill. Presentation of the face at the pelvic brim. right eye, malar bone, and adjoining parts. Thus the upper and right aspect of the face is lowest in the pelvis. As labor advances, and the head descends in the pelvis, the head gradu- ally turns, so as to bring the chin forwards from the right sacro- iliac synchondrosis to the right obturator foramen ; and in accomplishing this rotation from right to left, the chin is brought lower in the pelvis. The spine of the ischium in face, as in the ordinary vertex presentations, is the directing agent, and the chin of the foetus is the part acted upon in the latter. In the first cranial position, it will be remembered that the left side of the posterior extremity of the head glides down the inclined plane formed by the anterior surface of the left ischial spine, and that the head has thus a rotation imparted to it from left to right. In the facial presentation under consideration, it is in the left side of the chin which comes in contact with the anterior surface of the spine of the right ischium, and thus the rotation, although of an exactly similar nature, is in the reversed direc- tion, i.e., from right to left. In both pases, however, the same FLEXION IN FACE PRESENTATIONS. 391 general statement applies—namely, that the opposing surface of the foetus is thrown downwards and forwards under the arch of the pubis. As the chin advances and turns forwards, the arch of the cranium is directed backwards towards the hollow of the sacrum, and thus the head is completely lodged in the cavity of the pelvis. The right cheek and angle of the mouth are now the presenting parts, and the chin is just about to emerge from Fis. 112. Emergence of the head from the pelvis in face presentation. under the arch of the pubis. The next step is emergence of the chin, not exactly in the middle line, but still directed somewhat to the right, as in vertex presentations, where the antero-poste- rior diameter of the head is never exactly in relation with the antero-posterior diameter of the outlet of the pelvis. By the liberation of the chin, room is gained ; and now a process of flexion takes place analogous to the extension of vertex presen- tations : the chin becomes temporarily almost fixed, and the head rotates upon its transverse axis, so as to bring the vault of the cranium out with a sweep over the perinaeum, the occiput being the last part expelled. During the flexion described, there is an advance of the head en masse, but it is not so con- spicuous as the flexion. If the face remains long in apposition 392 TERMINATION OF FACE PRESENTATIONS. with the os externum, a secondary tumor forms on the cheek; but instead of being on the upper, it is on the lower half of the face, and involves more of the opposite side of the face than the primary tumor does. This is evidently in consequence of the depression of the chin, and the change from an oblique to an almost antero-posterior position of the long diameter of the face. The head having been expelled, the rest of the body behaves as in first vertex presentations. The right shoulder, being lowest in the pelvis, is propelled against the anterior surface of the spine of the right ischium, and rotated from right to left, so as to place the shoulders nearly in the antero-posterior diameter of the outlet of the pelvis. The right shoulder is thus born first, and the left sweeps over the perinaeum. The hips are born in the same manner. The engravings, No. Ill, 112, and 113, repre- sent the presentation of the face at the brim of the pelvis, at the outlet, and passing through the external parts. Fie. 113. Passage of the head through the external parts in face presentation. In the Second Facial Position, the details of the mechanism are exactly similar, only that the forehead is directed towards the right acetabulum, and the chin towards the left sacro-iliac synchondrosis, and all the rotations of the first position are INTERMEDIATE PRESENTATION OF THE FACE. 393 exactly reversed. In fact, by using the word "right" for "left," and " left" for " right," the description of the mechanism of a first facial position applies with the utmost precision to the second also. In the first position of the face, we may, while it passes through the pelvis, compare the situation of the chin to the situ- ation of the vertex in the third position of the head. The same rotation of the part first to emerge through the pelvis, from the right sacro-iliac synchondrosis to the right side of the pubic arch, is usually effected in both. We may also compare the second facial position to the ordinary termination of the fourth vertex presentation, the chin in this case rotating from the left sacro-iliac synchondrosis to the left side of the pubic arch. In face cases, the mental protuberance is the thread of the screw which is in contact with the ischial planes, and the rotation amounts to about one-fourth of a circle. As the chin passes out of the pelvis in the first facial position, it is in the same position as the vertex in the second cranial position; while in the second facial position, the chin emerges in the same path as the vertex in the first cranial position. Certain varieties of face presentations have been described, in one of which the chin has been spoken of as sweeping over the perinaeum. Smellie and Hamilton both include such cases in their systematic account of face labor; but with a normal ) pelvis and foetal head of the ordinary size, such a mode of ter- > mination is utterly impossible without the aid of instruments. There is an intermediate presentation in which the head is neither completely flexed, as in vertex cases, nor completely extended, as in face presentations : this was alluded to before, and is the brow presentation. On examining these cases at the commencement of labor, the frontal protuberance of the right or left side will be found to be as nearly as possible the pre- senting part. The diameter of the foetal head which enters the right or left oblique diameter of the pelvis, is that between the chin and the great fontanelle; the chin may be towards the right or left ilium. In the first, the presentation will be the analogue of a first vertex or face case, and the latter of a second vertex or face position. As labor advances, the head sinks down in the pelvis, and the right or left side of the face becomes most anterior and lowest in the pelvis, according to whether the 394 MISTAKES IN THE DIAGNOSIS OF THE FACE. case represents a first or second face case. The finger now easily arrives at the great fontanelle, which is anterior, and to the left or right, as the case may be, and in the opposite direction the chin may be found. Both the anterior fontanelle and the chin are higher in the cavity of the pelvis than the forehead. Unless the pelvis is very large, or the head of the foetus very small and yielding, the case now comes to a stand-still, the arch of the cranium being forced down upon the pubis, and the chin hooked against the upper border of the great sacro-sciatic ligaments. These cases require the aid of the forceps, and are difficult to manage, on account of the fact that these instruments can only be applied in this position to the face, over which they slip very easily. The diagnosis of face presentations may be considered to rest upon the absence of certain signs peculiar to other presen- tations, and upon the recognition of parts actually belonging to the face. The face may be distinguished through the mem- branes as a very uneven surface, totally dissimilar to the hard, smooth, globular mass of the vertex. If the head is very high, and the membranes tense and tough, it is not so easy to recog- nize the parts. It is still more difficult to determine the position through the walls of the cervix uteri. In a latter stage of labor, continued pressure may so modify the contour of the face, and induce such swelling of the features, as to simulate very much the general aspect of a breech presentation. In this case, the malar bones, with their soft coverings, may be mistaken for the ischia and buttocks, the mouth may be so swollen as to be easily confounded with the anus, or the eyes may be confounded with the vulva of a female child. When no peculiarly untoward circumstances are present to obscure the real nature of the pre- sentation, it is tolerably easy to recognize, the frontal suture narrowing towards the root of the nose, the ridge of the nose, the orbits on each side, with their bony circumferences, and, beyond the nose, the large cavity of the mouth and the firm edges of the alveolar processes. If any doubt exists as to whether the face or breech presents, the difficulty may be cleared up in certain cases by an appeal to the surface of the abdomen : thus, in thin women, the parietes of whose abdomens are lax, and in whose uteri there may happen to be but a small quantity of liquor amnii, the head may occasionally be recog- DANGERS OF INTERFERENCE IN FACE PRESENTATIONS. 395 nized externally as a spheroidal mass at the fundus of the womb, and this, of course, negatives the possibility of a face presenta- tion. On the other hand, the character of the meconium may become diagnostic ; for although it may be met with both in pelvic and cephalic presentations, yet, in the latter, it is in a diluted state, and is very different from the tenacious meconium of a breech case, which has not been mixed with the amniotic waters. We now arrive at the management of face presentations. In former times a great variety of contrivances were in favor amongst obstetricans for facilitating delivery in face cases. The foundation of this love of interference was evidently the strong conviction, which anciently prevailed, of the preternatural nature of the presentation, and this scientific prejudice found its practical development in procedures essentially meddlesome and bad. The first of these unphilosophical procedures was that of turning; it was of course only recommended when the head was high in the pelvis and the liquor amnii as yet undis- charged. Almost in the present generation turning has been recommended in face cases by high authorities. It is a well ascertained fact now that, even putting out of the question the danger which may accrue to the mother from the operation of turning, the result to the child is that the chances of death are more than doubled. The greater control which the accoucheur has over the progress of labor is certainly an attractive feature in the mode of practice ; but as very rapid delivery is by no means the great desideratum of obstetrics, it is as well to relinquish the control for the sake of additional safety. It should never be forgotten, too, that in all cases of version, however skillfully per- formed, there are certain risks to the mother, arising out of mechanical violence, inflicted either by the operator, or by the uterus upon itself; while shock and irritation, perhaps running on into inflammation, are but too frequently the results of manual interferences, in which no mechanical violence what- ever has been applied to the parts. Turning can only be admissible when there is such a complication as necessitates our putting the safety of the child out of the question, and balancing the operation of version against some more violent natural or artificial termination to the labor. Dr. J. Clarke adopted another plan, which was to wait until the head had 396 PROCEDURE IN FACE PRESENTATIONS. descended into the cavity of the pelvis, and then to exert steady pressure, in a direction upwards and backwards, upon the pre- senting cheek during each pain ; by this means he averred that he succeeded in lodging the face in the hollow of the sacrum, and that the labor then terminated as in vertex cases. What- ever may have been the results of this practice in the hands of Dr. Clarke, it is obviously attended with considerable risk; in the first place, success is very doubtful, and it is far more pro- bable that a brow presentation will be brought about than that a rectification will be produced ; and in the next place, the pro- cedure is a violent one as regards the child. A moment's con- sideration of the mechanical relations of the parts concerned will show that, as soon as any elevation of the chin is obtained, the arch of the cranium will be brought down upon the pubis ; and should the uterus act with any vigor, he will be a dex- terous operator who terminates the case without the forceps or some graver procedure still. A more pernicious mode of prac- tice than either of the above was first recommended by Baude- locque, and received the sanction of Lachapelle, as well as some British obstetricians. The operation was founded upon a mis- conception of the mechanism of labor in face cases of the fol- lowing nature. It was supposed that whenever the chin was towards the sacro-iliac synchondrosis of either side, the head must necessarily pass out of the pubis with the chin directed posteriorly. Whenever such cases had been actually observed, they had certainly been seen to be attended with a great risk to the foetus and suffering to the mother; but the grand error was, that not only are mento-posterior presentations, as a general rule, changed into mento-anterior ones, but that, instead of mento- posterior positions being exceptional and peculiar, they are the most frequent of face presentations. The fact that the chin was generally towards one or other sacro-iliac synchondrosis was not known, and the rotation of the chin forwards in nearly all cases was equally undiscovered. It was thought that an original anterior position of the chin was the only favorable position in face cases, and knowing as we now do as to the infrequency of this presentation, it can hardly be a matter of surprise to us that such frequent manual interference was resorted to, and that such an unfavorable prognostic was applied to face presentations in general. The operation was performed quite in the early DANGERS OF BAUDELOCQUe's OPERATION. 397 stage of labor, and before the membranes were ruptured. It was recommended to introduce the hand into the vagina, through the os uteri, and into the space between the brim of the pelvis and the forehead of the foetus; the palmar surface of the fingers being kept towards the head of the child. The next step was to rupture the membranes and hook the fingers over the arch of the head, and drag down the occiput if possible—indeed this is the object of the procedure—and thus convert the face presenta- tion into an ordinary vertex one. The objections to this method are numerous. Since Naegele wrote his celebrated treatise on the mechanism of labor, it has been generally known that not only is the chin at first generally directed backwards, but that, in nearly all cases, it turns forwards under the arch of the pubis as a necessary result of normal relations between the pelvis, the foetal head and the expulsive powers. Having thus eliminated a large proportion of cases from the category of those requiring artificial assistance, let us inquire, What are the dangers of Baudelocque's operation ? It must be granted that the intro- duction of the whole hand at the commencement of labor, before the external organs of generation are dilated and softened, must be an extremely painful procedure for the mother, and the efforts used for the introduction of the hand into the uterus can hardly fail not only to be painful but to give rise to serious accidents. M. Moreau saw a case in which rup- ture of the uterus, followed by immediate death, was the result of this operation, and the circumstance is the more worthy of notice, because the operator was a person well used to obstetric manipulations. In the next place, the sudden escape of the liquor amnii before the head has become engaged in the superior strait of the pelvis is very likely to result in descent of the funis, a circum- stance which places the foetus in extreme peril. Again, an arm may descend, or even two may come down, and create additional difficulty in the further progress of the case ; and, finally, it is an inseparable result of these tentative efforts, that when they fail to produce a vertex presentation, recourse must be had to the forceps or pelvic version. It may be added, that the early evacuation of the liquor amnii is a circumstance extremely objectionable in itself, as subjecting the foetus to the immediate pressure of the uterine walls, and abrogating all 398 TREATMENT OF FACE PRESENTATIONS. those arrangements which conduce to easy delivery in a spon- taneous vertex presentation. If the operation were easy and inoffensive, and if it placed both mother and foetus, after its accomplishment (always supposing it to have been accom- plished), in the same condition which would have obtained in a spontaneous vertex position; if, in a word, the least analogy existed between a labor where the vertex presents spontaneously and one in which it had been dragged down, it would be proper to resort to Baudelocque's method; but inasmuch as failure is probable, the condition produced not identical, the danger to mother and child from the operation itself not small, and the alternative after failure another and still graver operation, the whole proceeding is totally inadmissible. In actual practice, it will be found that the treatment of face cases is extremely simple. We may assist the chin in making its rotation forwards and downwards, by introducing the finger into the child's mouth, making traction upon the lower jaw, and bringing it under the arch of the pubis. Meigs lays it down as the great rule of practice in face cases, that the chin should be brought towards the pubis as the face emerges from the pelvis. This is an analogous procedure to that of bringing the occiput down in vertex cases, either directly, by the fingers applied to the back of the head, or indirectly, by pressure exerted upon the forehead. The principle is the same in both cases—viz., to favor the birth of that part which tends to be born first. Should the head fail to rotate in the pelvis the for- ceps will generally be necessary, or the head must be dislodged, and the child delivered by turning. Where delay arises, not from faulty position, but from disproportion in bulk between the head of the foetus and the pelvis of the mother, or from inadequate uterine contraction, the same rules of treatment apply as in cases of impactment or inertia uteri, where the ver- tex presents with this modification, that as the parts engaged in the pelvis are more solid, less advantage will be gained by delay in so far as moulding of the head is concerned, and more danger will accrue to the mother from pressure upon the rectum and bladder. The foetus itself is more endangered, too, by lone engagement in the pelvis, in face than in vertex positions, the vessels of the neck being often injuriously pressed upon. During the progress of a face case care should be taken to keep NECESSITY OF CARE IN EXAMINATION. 399 the pelvic viscera empty, and to preserve the membranes entire as long as possible. In making examinations, the delicate struc- ture of the organs within reach should be remembered, as cases not unfrequently happen in which the eyes have been seriously injured by careless manipulations. Examinations should not be more frequent than necessary to determine the exact presenta- tion at first, and the subsequent rate of progress. The apart- ment should be kept cool, and the patient's courage supported by a cheerful and confident demeanor on the part of the accoucheur. The perinaeum should be carefully guarded, but not pressed upon. After birth, the features of the child will generally be found hideously distorted, the mouth dragged to one side, and one or both eyes occluded. Fomentation with warm water, decoction of poppy-heads or marsh-mallow, will be all that is necessary, as the parts will gradually return to their normal condition. The parts of generation of the mother require similar application and great cleanliness. LECTURE XXVII. PELVIC PRESENTATIONS. Gentlemen :—Having considered those presentations in which the cephalic extremity of the foetus is situated inferiorly, we may naturally pass to those in which the pelvic extremity of the child holds the same position. It has been a matter of contro- versy whether pelvic presentations should be considered natural or preternatural. Whatever arguments have been urged on either side, however, the same detriment has not accrued to prac- tice as from erroneous theoretical opinions with regard to the nature of face presentations, inasmuch as all have been agreed pretty nearly as to the time and manner of rendering assistance in these cases. Practical conclusions not having been deduced from the one or other view of the question, all interest in it vanishes, and we are left free to consider only that which is use- ful. It is by no means necessary to enter into detailed separate descriptions of the various forms of pelvic presentation ; they are in reality, but trifling varieties of the same order of labors, and differ very little except in some particulars of management: their mechanism is essentially the same, and the fundamental rules of treatment which apply to the one variety apply with equal force to the other. We may look upon the pelvic extrem- ity of the foetus as composed of certain elements, which may present alone, or in certain combinations. The most complete variety is where the breech engages itself in the pelvis first; then the knees may present, or the feet, or a single foot or knee. A needless subdivision of breech presentations has been made by some authors, and the pelvis of the foetus has been described as occupying almost every conceivable position at the brim of the maternal pelvis. The complexity thus given to the subiect of the mechanism of pelvic labors was, however, first cleared 400 ANALYSIS OF PELVIC PRESENTATIONS. 401 away by the same careful observer to whom we are indebted for nearly all that we know, exactly, of the intra-pelvic movements of the foetus. Naegele* reduced all pelvic presentations into two orders ; in the first, the back of the child is towards the abdo- men of the mother; in the second, the abdomen of the child is towards the mother's abdomen. These may be called respec- tively the dorso-anterior and the abdomino-anterior positions. In neither case, however, is the back of the foetus situated quite anteriorly or posteriorly, but rather obliquely, so that one hip is more anterior than another. The dorso-anterior position is, according to the same authority, more frequent than the reverse presentation, in the proportion of three to one. Let us now examine the mechanism of pelvic labors, first premising that they ensue according to the fixed laws, as cranial labors do, with only this difference, that deviations from the usual course are perhaps rather more frequent, and attended with less risk than when the head presents. Fig. 114 Pelvic presentation in the first dorso-anterior position. In dorso-anterior pelvic presentations, the relation of the foetus to the maternal pelvis, is, generally speaking, as follows: the tftmsverse diameter of the child's hips occupies the left oblique 26 402 ROTATION OF THE BREECH. diameter of the pelvis, its sacrum is directed towards the left acetabulum, its left trochanter towards the right acetabulum, and its right trochanter towards the left sacro-iliac synchon- drosis. Upon examining per vaginam, as the breech is enter- ing the superior strait of the pelvis, it will be found that the os uteri is occupied by a double tumor, soft, but elastic dur- ing the intermission of a pain, the several parts to which refer- ence will be made, when speaking of the diagnosis, may be readily distinguished, and it will be found that the sulcus between each segment of the tumor is oblique, and situated more posteriorly than anteriorly; or, in other words, one but- tock, the left, occupies the anterior and greater half of the mouth of the uterus. It will be observed, also, that this but- tock, which is most anterior, also stands lowest in the pelvis, and is, in fact, the presenting part. As labor advances, and the hips descend, the left hip is still lowest in the pelvis, and steadily directed somewhat to the right: what now takes place is a matter of dispute. The great majority of obstetricians con- tend that a rotation analogous to the rotation of cranial labors takes place, that the left hip turns more and more forwards, until it comes to be nearly under the pubic arch, and that the hips and shoulders thus emerge from the pelvis, nearly in the antero-pos- terior diameter of its outlet. This statement is made confidently by persons of great and deserved repute, but M. Naegele, never- theless, flatly contradicts it, and makes it the subject of some pleasantry ; his words are nearly as follows: " In its farther advance (the breech) into the pelvis, it is always found in an oblique direction, the hip directed forwards standing lowest. In this oblique position, with reference to its transverse and perpen- dicular diameters, it is forced through the inlet, the cavity, and the outlet of the pelvis; and in general none of these rotations occur, erroneously described in many manuals and compendia as appertaining to this species of labors. There are some, cer- tainly, who, compass and skull in hand, measure the diameters of the bony pelvis, and then on the writing desk so turn and extract a mannikin, that the transverse diameter of the hips always passes in that direction, which, according to calculation on the bony pelvis, they account the largest." The truth as usual, would appear to lie between the contending parties. That there is a slight rotation can hardly be doubted, but it is ROTATION OF THE BODY OF THE FCETUS. 403 not so constant nor so well marked as the rotation of the cranium. There is not the same difference between the diame- ters of the breech of the foetus as between the diameters of its head, and consequently there is not the same necessity for a movement of adaptation ; we shall find, however, that the head obeys the same mechanical necessities in its transit, in pelvic labors, as when it presents at first. Supposing the breech now to have become entirely engaged in the cavity of the pelvis, the left hip will be found just within the vulva, and the right hip beginning to press down on the floor of the pelvis posteriorly, and somewhat to the left side. The left hip then becomes nearly fixed under the pubic arch, and a movement of flexion takes place analogous to the flexion of face and the extension of ver- tex labors ; the right hip sweeps over the perinaeum, the pelvis of the foetus rotating, as it were, upon its antero-posterior diame- ter. As soon as the right hip has escaped from the tight embrace of the perinaeum, a movement onwards en masse takes place, the Fig. 115 Passage of the shoulders, and partial rotation of the thorax. feet usually slip out, and presently the knees become disengaged; and the inferior half of the child's body is thus born. The abdo- 401 DELIVERY OF THE ARMS. men of the foetus is now turned towards the inner side of the rio-ht thigh, or, supposing the woman to be in the ordinary obstetric position, upwards. The rest of the body follows in the same manner, the shoulders entering the left and oblique diame- ter of the inlet. The manner in which the arms are born depends upon whether they remain folded upon the chest of the foetus, or are displaced during the progress of labor. In the first instance they slip out as the thorax is expelled ; in the lat- ter they are extended upwards on each side of the head, or one may even become locked behind the head, and between it and the pubis; and serious inconvenience may arise from such an accident. If the arms remain extended by the side of the head as the latter passes through the pelvis, the difficulty of the case is of course enhanced. The left shoulder of the foetus, like the first hip, becomes first engaged in the outlet of the pelvis, and the right shoulder distends and sweeps over the perinaeum. Durinc- the whole progress of labor, the foetal head will in most cases remain flexed upon the chest. As the shoulders are about to emerge, the head enters the opposite oblique diameter of the pelvis to that which the hips and shoulders have occupied; thus the forehead is towards the right sacro-iliac synchondrosis, and the occiput is directed towards the left acetabulum. The occipito-frontal diameter of the foetal head is not, however, exactly that which comes into relation with the right oblique diameter of the pelvis, for the chin is depressed and the occiput is the highest point of the foetus ; it is the sub-occipito-frontal diameter which presents, and thus sufficient room is gained to allow the head to become easily engaged in the cavity of the pelvis, and to permit the face to be rotated into the hollow of the sacrum. The under surface of the occiput now rests against the inner surface of the symphysis pubis, the mass of the face occupies the sacral concavity, and the chin may be felt some little way within the perinaeum. In the further expulsion of the head the occiput is almost a fixed point, and the head rotates -upon its transverse axis in such a manner that first the chin sweeps over the perinaeum, then the face, the forehead, and the arch of the cranium ; and finally, the bulkiest part of the head having been expelled, the rest is pushed out by the elasticity of the perinaeum and the action of the vaginal muscular fibres. In the second variety of dorso-anterior positions, the hips SECOND VARIETY OF BREECH PRESENTATIONS. 4Q5 of the child occupy the right oblique diameter of the brim of the pelvis; the right buttock presents, if it is a breech case, and Fia. 116. Descent of the head. occupies the greater and anterior segment of the os uteri • and the left buttock sweeps the perinaeum. The right side of the foetus is directed steadily somewhat to the left acetabulum and its abdomen turns downwards, or towards the left thigh of the mother. The head enters the left oblique diameter of the pelvic inlet, the forehead being towards the left sacro-iliac synchon- drosis ; the face turns into the hollow of the sacrum, as in the first instance, and the whole progress of the case is, in fact the converse of what happens in the first position ; just as the second is the converse of the first vertex or face presentation. Abdomino-anterior positions of the foetus, with the breech or lower extremities presenting, are of two Icinds. In the first and most frequent variety, the hips of the child occupy the right oblique diameter of the inlet, the left trochanter is towards the left acetabulum of the mother, the left hip presents and stands lowest in the pelvis from first to last, and the whole body, as far as the shoulders, is expelled, looking forwards to the right. 406 ANOMALIES IN PELVIC LABORS. The head enters the left oblique diameter of the inlet of the pel- vis, the occiput being towards the left sacro-iliac synchondrosis. As the head descends, in the pelvis, the occiput rotates forwards from left to right until at last the face is lodged in the hollow of the sacrum, just as it rotates in fourth vertex positions. Those parts of the foetus which were already born may now be seen to rotate in a corresponding direction and degree to the intra-pelvic rotation of the head ; thus the anterior surface of the child's body, which at first looked forwards and to the right, now looks backwards and to the right, and the case then terminates exactly as the first sub-order of dorsal anterior positions. The second variety of abdominal anterior positions is where the hips of the foetus lie in the left oblique diameter of the inlet, the right trochanter being towards the right aceta- bulum. The right buttock is here the presenting part, and stands lowest in the pelvis. The head enters in the right oblique dia- meter of the inlet, with the occiput towards the right sacro-iliac synchondrosis, and undergoes the same kind of rotation as the preceding variety—that is to say, the occiput turns forwards and from right to left, and the face is thus thrown into the concavity of the sacrum. The anterior surface of the child's body, which was at first turned forwards and to the left, is at the same time rotated so as to look backwards and to the left. The mechanism of this variety is in fact the exact converse of the preceding. There remain two anomalies in the mechanism of pelvic labors, which are very interesting; one of these relates to an unusual termination of cases in which the abdomen of the infant is anterior, and the other relates to the position and rotation of the fcetal head. It sometimes happens, says Naegele, in abdominal anterior positions where the foetus is premature, small, or a twin, that the abdomen, which was at first directed forwards and to the left, or forwards and to the right, is suddenly, and during a single pain, turned so completely round that the abdomen looks backwards and to the right, or backwards and to the left. It is difficult to account for such a singular revolution of the fcetal body. The other anomaly alluded to is where the head, instead of being fixed upon the chest, is extended, the occiput being pressed down upon the nape of the neck. In such cases the ver- tex rotates backwards into the hollow of the sacrum, the under sur- face of the lower jaw is brought into relation with the symphisis DIAGNOSIS OF BREECH PRESENTATIONS. 407 pubis and the head emerges in such a manner, that, first, the occi- pital protuberance sweeps over the perinaeum, then the arch of the cranium, and then the forehead and face. The foregoing account of the mechanism of pelvic labors applies in-every essen- tial particular to each variety. There are, however, one or two subsidiary differences depending upon whether the nates, knees, or feet present. When the breech presents, the birth of the body is slower, but the head follows more readily; when the knees descend, they sometimes create delay by becoming fixed against some point of the bony pelvis, more especially against the lower part of the sacrum; and when the feet present, the birth of the lower half of the body is comparatively rapid, while delay ensues in the passage of the shoulders and head. In labors where the breech or knees present, reliance may be placed upon the posi- tion of the presenting part, as an index of the actual position of the foetus; but when the feet present, it must be borne in mind that they are very mobile, and only affect a determinate position when the nates enter the brim of the pelvis. In some cases of pelvic presentation, it has been remarked by Drs. Hardy and M'Clintock, that the anterior-superior spinous process of the ilium presents, in the first instance, and may cause some confu- sion. The diagnosis of pelvic presentations rests upon signs, some of which are common to each variety, while there are par- ticular signs by which each special presentation may be deter- mined. The first thing to which the attention is directed in pelvic presentations is the absence of those familar conditions which obtain when the head of the foetus is at the brim of the pelvis ; and,, failing to recognize these, the accoucheur naturally looks for data upon which to found a positive diagnosis in lieu of his negative one. Popular opinion, amongst females at least, attaches much importance to the external configuration of the abdomen, and hence the slightest deviation from the usual form or size excites in women strong apprehensions of mal-position of the child. As long, however, as the long axis of the ovoid mass formed by the foetus corresponds to the long axis of the uterine cavity, it will make but little difference in the external appear- ances whether the cephalic or pelvic extremity of the foetus is directed downwards. Even in transverse presentations it is sur- prising how little affected is the figure by the position of the 408 CHARACTERISTICS OF BREECH PRESENTATIONS. contained infant, and to expect therefore any guidance in the minute difference in form and size between the upper and lower extremity of the foetus is chimerical in the extreme; it is only in very exceptional cases that an external examination throws any light upon the subject, and even then it is not from the general appearance we judge, but because we can occasionally, under favorable but peculiar circumstances, recognize the rounded mass of the fcetal head, through the walls of the abdo- men, lying at the fundus uteri. It has been said that when the breech presents, the lower end of the utero-foetal tumor sinks further down into the pelvis at the commencement of labor than when the head presents, and this has been said to occur whether the case is a primiparous one or not. The fact, however, if it be one, will not assist us very materially ; for the depth to which the presenting part sinks in the pelvis, independently of uterine contraction, is principally the result of circumstances uncon- nected with the foetus, such as the size of the pelvis and the tension of the abdominal walls. In knee and footling cases, the presentation is certainly further out of reach at the commence- ment of labor than when the head is at the brim of the pelvis, and indeed it not unfrequently happens in footling cases that it is extremely difficult to find any presentation at all, unless the whole hand is introduced into the vagina. The form of the bag of membranes is an item better worth attention ; it will be found not to have that rounded form which obtains under ordinary circumstances, and it projects more into the vagina. In footling cases the bag is quite long, and shaped like the finger of a glove, and in all pelvic presentations it is not so tense as when the head presents. Another circumstance worth attending to is the mobility of the presenting part, which in pelvic presentations is generally more resilient, and bounds up in the waters of the amnion more readily than the head does. The sensations of the mother have also been spoken of, as furnishing an indication of the position of the foetus, not to be neglected. In vertex pre- sentations, the feet of the infant are of course directed towards the fundus uteri, and the sensations of struggling felt by the mother are generally referred to the upper portion of the uterus, and more especially to where it is in contact with the abdominal parietes. When the pelvic extremity of the foetus is its depend- ing portion, these sensations are said to be in a great measure DIAGNOSTICS OF BREECH PRESENTATIONS. 409 absent, or if perceived, to be referred to a much lower situation. Very little reliance can be placed upon auscultation in deter- mining pelvic presentations. The fcetal heart beats so nearly midway between the one extremity of its body and the other, that but little alteration in the distance from the pubis, at which it is best heard, is effected, whether the cranial or pelvic extrem- ity of the foetus depends. When it is remembered that con- siderable variation in this respect obtains in cranial presenta- tions, it must be conceded that, however useful auscultation may be in other circumstances, we can expect but little assistance from it here. In the first dorsal anterior position the foetal heart may be heard loudest a little to the right of the mesial line,, and somewhat below the level of the umbilicus ; in other positions the sounds of the heart are somewhat obscure, and, in short, auscultation is not to be relied upon. The manner in which the liquor amnii is discharged is peculiar, though not so character- istic in breech as in knee and footling cases. When the head presents, the membranes rupture, and a sudden gush of water follows, which as suddenly stops; this is because the head is forced down upon the os uteri, and acts as a ball-valve. In pelvic presentations, the gush is not so sudden, and the waters of the amnion continues to flow until the uterus is emp- tied of all its contained fluid. As might be naturally expected, the character of the pains alters as soon as the membranes have burst, and from this time until the whole body is expelled, and nothing remains but the head in the cavity of the pelvis, the uterine contractions are more clonic, continuous, and closer together than in cranial labors; the absence of fluid from the uterus multiplies the points of contact between the foetus and uterus, and increased excitation results in increased motor action. The chief and conclusive evidence of pelvic presentation is, of course, the recognition of the individual parts which offer them- selves to the touch per vaginam. In breech cases, very little can be accurately distinguished before the membranes are ruptured, beyond the movable coccyx and rugosities of the sacrum; these can generally be felt behind one or the other acetabulum. As soon as the liquor amnii has escaped, however, the finger of the accoucheur comes into direct contact with the parts of the foetus. The os uteri will be found occupied by two smooth elastic tumors, divided by a cleft, which extends in one direction towards the coccyx 410 PECULIARITIES OF PELVIC PRESENTATIONS. and sacrum, and in the other, is continuous as far as the finger can reach. In the track of this cleft, the anus may be distin- guished ; it differs from the mouth in being smaller, in not con- taining alveoli and a tongue, and in contracting upon the finger if any attempt is made at introduction. In dead foetuses, the anus is relaxed, but the distinction may be easily made by refer- ence to the other differences. The vulva of a female child may be distinguished from the mouth in the same manner. Further from the coccyx than the anus, the genitals may be recognized; and in the case of a male child, the scrotum, which sometimes hangs down much tumefied, is a very distinctive feature. The meconium which comes away upon the finger in breech cases is tenacious and adhesive. If the breech remains long in the pas- sages considerable tumefaction takes place, and the diagnosis is to a certain extent obscured ; but prolonged and careful exami- nation will generally suffice to overcome this difficulty. The knee may be recognized by its presenting for examination two rounded tuberosities, with a depression between them and the flexure of the leg and thigh, which can easily be reached. The knee is liable to be confounded with the heel, the elbow, and the shoulder ; it differs from the heel in having two tuberosities; from the elbow in having a depression, instead of the sharp point of the olecranon, between its tuberosities ; and from the shoulder in having two tuberosities in the place oione, from which the bony ridges of the clavicle and scapular spine may be traced. The foot is liable to be mistaken for the hand, but it may be identified by the following peculiarities : In the first place, the line of the toes is regular and even, while the fingers are of various lengths, and form an irregular line. The great toe lies close to the other toes; the thumb, on the contrary, divaricates, and is opposed to the other digits. The foot is thicker than the hand, and its inner border is much rounder than its outer bor- der. Tlie rounded instep of the foot has no analogue in the hand. The heel projects in the opposite direction to the toes. The foot is at a certain angle with the leg, while the hand is continuous in the same direction with the arm ; and finally, the foot is weightier, and not so mobile as the hand. In breech cases, it is easy to determine the exact position of the foetus and there is no great difficulty in doing so when the knee presents • but in footling cases it is not so easy. If only one foot comes INTERFERENCE IN BREECH CASES. 411 down, it is as well not to be positive until the hips enter the brim of the pelvis ; but if both descend, and cross each other, the anterior surface of the body must be in the direction of the toes. When one foot comes down, it should always be identified as right or left. Having fully satisfied ourselves of the exact position of the foetus, we have little to do until towards the conclusion of labor. The accoucheur should be an observant spectator of the operations of Nature, thoroughly cognizant of what those operations are, and capable of appreciating at once the slightest departure from their normal course. The first care should be, not to rupture the membranes. In knee and footling cases this caution is even more necessary than when the breech presents. The bag of membranes is required to the last moment, as a dilating agent; no part of the foetus in pelvic presentations will dilate the pas- sages so equitably or so efficiently as the waters of the amnion. A solid body, not possessed of the globular form of the cranium, will exercise pressure in certain directions, according to its specific form: water presses equally in every direction, and the waters therefore we should endeavor to retain within the membranes as long as possible. This is a cardinal point in the management of pelvic labors. Ancient practice in this particular was very dif- ferent from modern, and opposed so obviously even to d priori considerations, that it is difficult to conceive the necessity of the hard teachings of experience to show its defects. Dr. William Hunter, at one time, used to convert all breech cases into foot- ling ones; subsequently he was less disposed to interfere with nature, and he then found his proportion of deaths in pelvic labors very much diminished. Smellie's advice sounds some- what singular in modern ears ; he says, " If the knees or feet of the child present to the os internum, which is not yet sufficiently dilated to let them and the body come down, let the operator introduce his hand into the vagina, push up and stretch the os uteri, and bring along the feet." Supposing the membranes to be ruptured, the best rule is to let Nature take its own course until the body is born as far as the umbilicus ; only guarding the perinaeum, and relieving it of tension by favoring the flexion of the trunk. The less we interfere the less rapid will the descent of the foetus be; and it is very important to secure, if possible, a slow passage of the pelvis and trunk, and consequent complete 412 ASSISTANCE IN PELVIC PRESENTATIONS. dilatation of the passages. If the knees descend and accidentally get locked in the cavity of the pelvis, they must of course be lib- erated ; but this is an accident, and not the usual course of events. The laissez faire system does nor apply, of course, to cases of inertia uteri; if the breech or hips of the child do not advance, from defect of uterine contraction, either the uterus must be excited, or traction must be made upon the foetus. Various methods of applying tractile force have been adopted : the finger may be hooked in the groin, or a silk handkerchief passed round the flexure of each thigh, or the blunt hook may be used. A dexterous obstetrician will generally succeed with the unaided hand, and, indeed, the blunt hook is an unnecessary formidable instrument for such purposes ; it bruises soft parts, and is very likely to fracture the thighs of the foetus. When the umbilicus clears the perinaeum, the dangerous part of the labor begins; an abnormal element—viz., compression of the funis—is introduced into a process otherwise normal; and now our art must be exer- cised and imposed between the foetus and impending death. The first interference necessary is to draw down a loop of the cord; this is done with a view to obviating any compression which may arise from straightening out of the spirally-coiled umbilical vessels, in the further descent of the trunk. An effort should then be made to draw the cord into one of the recesses on either side of the promontory of the sacrum, as this position is one in which there is less risk of pressure than in any other. The strength of the funicular pulsations should now be narrowly watched, as it bears a direct ratio to the chances of live birth ; as long as the cord beats steadily, no interference is necessary, and indeed should be avoided. It is very tempting to see the * legs dangling, out ready to be grasped, and to know that the foetus may be seized and dragged forth without much delay, and the bystanders will generally applaud the zeal of the accoucheur who endeavors to hasten the birth under these circumstances; but it sometimes happens that premature efforts at traction dis- lodge the arms from their position on the child's breast, and throw them up on each side of, or even behind, the head; and it again results, at other times, that the head becomes extended that the arch of the cranium is rotated into the hollow of the sa- crum, and that the child is lost from consequent delay in the passage of the head. Until there is a valid reason, then, for THE FUNIS IN BREECH CABES. 413 interference, arising out of the condition of the foetus or the mother, nothing should be done. As the chest is being forced out, it is necessary to be observant of the position of the arms; if they are in their natural position they will slip out of them- selves, but if they are extended on each side of the head it will be proper to bring them down. It is best to bring down the arm nearest the perinaeum first, as there is more room for mani- pulation in that direction. One of the two fingers should be hooked round the humerus, near the elbow-joint, and the arm should then be drawn gently over the face and chest, not dragged directly downwards. Inattention to this precaution may pro- cure the disagreeable accident of fracture of the humerus. This is not a very uncommon accident in midwives' midwifery, and indeed it was of old a rule of practice amongst them to break the arms, as an expeditious and simple method of meeting this difficulty of pelvic labors. The other arm should be dealt with in the same manner. As the shoulders are born the perinaeum again requires care, and as soon as they are liberated the face will generally rotate into the hollow of the sacrum. The largest and most unyielding part of the foetus has now to be expelled, at a great mechanical disadvantage. The uterus is so far empty as to have lost much of its power over what remains behind, and the birth of the head is, in fact, principally effected by the diaphragm, abdominal muscles, and muscular structures within the pelvis. Danger accrues to the foetus more than ever now, from pressure on the cord; and the placenta is so jammed down upon the head of the child as in a great measure to destroy its function as a respiratory organ. This is the stage of labor in which life is generally lost, in which the natural powers avail least, and in which the intervention of art is therefore most needed. It is necessary still, howeverj to be guided by the actual condition of the child ; if the cord beats steadily it is bet- ter to wait for a time than to interfere hurriedly. The signs of danger to the child are increased quickness and feebleness of the umbilical pulse, and occasional gasping respiratory movements. Whenever it happens that, once or twice in the course of a min- ute, inspiratory movements of the muscles of the chest and abdo- men are observed, the head of the child remaining as yet in the pelvis, we may be sure that the child is dying of asphyxia. These movements are caused, as is proved by the experiments 414 TERMINATION OF PELVIC PRESENTATIONS. of Volkmann and Schneider, and the observations of Dr. Mar- shall Hall, by the centric irritation of the medulla oblongata by the carbonized blood of the foetus, in cases of pressure upon the placenta or funis. No other sign of danger to the foetus is so trustworthy as the occurrence of these jerking spasmodic attempts at respiration. The necessity of interference being clear, there is no great diffi- culty in rendering it. A finger or two of the left hand should be introduced into the child's mouth, or laid one on each superior maxilla, and the face should be drawn steadily down towards the fourchette of the perinaeum ; at the same time, the occiput should be pushed up by a finger or two of the right hand intro- duced behind the symphysis pubis. This manoeuvre will bring the shortest possible diameter of the fcetal head into relation with the antero-posterior diameter of the outlet of the pelvis. The head will emerge now, with the aid of gentle traction, towards the knees of the mother, and the birth is complete. Whether the position of the foetus is a dorso-anterior one, or an abdomino- anterior, the management varies hardly at all. The occiput rotates forwards from its posterior position just as in thirds and fourth vertex cases; and nature will generally adapt the head to the pelvis much better than the accoucheur. No force should be used in the extraction of the head. Above all, traction should never be exerted upon the shoulders, as very slight ex- tension of the neck is sufficient to destroy the child. The stretch- ing of the upper part of the spinal marrow is very dangerous to the life of the infant. Where the head in breech cases is impacted at the outlet of the pelvis, it is sometimes possible to pass up two fingers to the mouth of the child, and to admit a sufficient quantity of air to allow of respiration before the delivery of the head. This was first recommended by Pngh, and Dr. Bigelow, acting upon the same principle, recommended the use of a flat flexible tube for the same purpose. The forceps should always be had in readiness in breech and footlino- cases. When the head cannot be delivered, or respiration set up by the processes described, and when the danger of the child is imminent the forceps should invariably be used. A delay of a minute or even a few moments may sacrifice the life of the foetus. The forceps is still more likely to be required in footling than in breech cases. When the child is dead or premature, particularly in the former AFTER CARE OF THE F03TUS. 415 case, less precaution is of course necessary in extracting the head. Manual extraction of the head. Delay and difficulty may occur at various stages in the pro- gress of pelvic labors; thus* there may be ascites, or accumula- tion of urine in the foetal bladder; or the child may be tym- panitic ; or there may be hydrothorax, or hydrocephalus. Any of these accidents may render evisceration necessary. Anchy- losis of the coccyx with the sacrum, or a flat or too incurvated condition of the latter bone, will sometimes prove a serious source of delay and danger to the foetus. Sometimes the os uteri seizes the neck or head of the child, and retards delivery. It is proper, in cases where the breech or lower extremities pre- sent, to be prepared with the necessary means of restoring sus- pended animation. An abundant supply of hot water for baths, and a gum-elastic catheter for inflating the lungs, should be at hand. If there is much cerebral congestion, it will be advisable to allow two or three drachms of blood to escape from the funis. Friction of the surface of the body, aspersion with cold water, [alternating with the warm bath, to produce the nervous shock, as recommended by Marshall Hall], and galvanism, maybe had 416 STATISTICS OF BREECH CASES. recourse to with benefit. [The " ready method " should not be forgotten in the asphyxia neonatorum.] It is always interesting to note the Influence of mal-pre- sentations upon the life and subsequent condition of the mother and foetus. As far as mother is concerned, it can hardly be said that there is any appreciable difference in the risk of cephalic and pelvic labors. Non-expulsion of the head is the circumstance most likely to prove detrimental to the mother ; and bruising of the parts within the pelvis from impactment, or the supervention of inertia uteri followed by flooding, are the forms of danger to which she is exposed. The danger which accrues to the child is, however, very considerable. In breech cases the deaths are as 1 to 3j, and in footling cases as 1 to 2£. The gross proportion of deaths in all presentations of the pelvic extremity of the foetus is about 1 to 3. Death takes place from asphyxia, either produced by compression of the cord or of the placenta, or from early detachment of the placenta, or coma is produced by obstruction of the veins of the neck, and, lastly, the infant may perish from shock or exhaustion. Instrumental interference is based, of course, upon the same general princi- ples which apply to other forms of parturition. Spontaneous pelvic presentations are less dangerous both to mother and child than the artificial pelvic presentation procured by the operation of version. According to Dr. Fleetwood Churchill's collection of nearly 200,000 cases, the breech presented in the proportion of about 1 in 59^ ; footling or knee presentations were about 1 in 105 cases. LECTURE XXVIH. TRANSVERSE PRESENTATIONS. Gentlemen :—In the preceding lectures we have considered those presentations in which the cephalic or pelvic extremities of the fcetal ovoid are found at the os uteri. We have now to treat of those presentations in which the long diameter of the foetus is opposed to the short or transverse diameter of the uterus. These cases are termed Transverse or Cross births, and include the presentation of the shoulder or some other part of the superior extremity, and the presentation of any part of the dorsal or abdominal surfaces of the child. The most important, and at the same time the most frequent, are those in which the shoulder, elbow, or hand present, all of which are spoken of as arm presentations. To these cases we may chiefly direct our attention, as the cases in which some portion of the body presents are treated according to the same principles as arm cases. In arm presentations, two principal positions are recog- nized, depending on the relations which exist between the abdomen and dorsum of the foetus, and the back and abdomen of the mother. In the majority of transverse births, the back of the child is directed towards the abdomen of the mother; in a small proportion, the back of the foetus is towards the maternal spine. These varieties may be termed the Dorso-anterior, and Abdomino-anterior positions. They occur in the proportion of two of the former to one of the latter. Besides the abdomino-anterior and abdomino-posterior positions, there are four subsidiary varie- ties in the position of the child in arm cases, depending on the situation of the foetal head on the right or left side of the mother. In the dorso-anterior position, the head may be on the left side of the mother, in which case the right shoulder or arm is the presenting part; or it may be towards the right iliac fossa, when 27 417 418 VARIETIES OF ARM PRESENTATIONS. the left upper extremity is the presenting part. In the abdomino-anterior positions, the head may be directed to the Fis. lis. Arm Presentation in the Dorso-anterior Position. right or left side of the mother. When it is to the left, the left arm, and when it is to the right, the right arm of the foetus Fie* 119, Ann Presentation in the Abdomiro-anterlor Position. DIAGNOSIS OF ARM PRESENTATIONS. 419 presents. As far as I am aware, no observations have been made to determine the relative frequency with which the child's head lies to the right or left side in arm cases. But this is pro- bably a point of little importance, as the management is the same in all these variations of position. Numerous complica- tions are met with in transverse presentations. Besides the pre- sentation of any part of the body, the arm and head, both arms, the funis and arm, or an arm and foot, may descend together. Perhaps we scarcely ought to consider the descent of the arm and head, or of the hand and foot, as strictly transverse presentations, since it is a mixture of the transverse and the cephalic or pelvic, and may terminate in the case of the hand and head, in cephalic, or in that of the hand and foot, in pelvic delivery. There are no distinct signs of the occurrence of transverse presentation before the commencement of labor which can be depended on, though we know that in many of these cases the preternatural position is assumed some time before the date of labor. In some cases, the width of the uterus and abdomen is noticeable; but when this is the case, it is difficult to form a diagnosis between the child lying in the transverse diameter of the uterus and twin pregnancy. In many cases there is no deformity in the shape of the uterus. In some women, the sub- jects of cross-births, uterine cramps and spasms are complained of; but in others nothing of this kind occurs, and labor comes on slowly, and, one may almost say, more insidiously than in other cases. Owing to the absence of the head from the os uteri, the dilatation goes on more slowly and painlessly than usual. This is a disadvantage, inasmuch as labor is hardly suspected, and the accoucheur may not be sent for until considerable progress has been made. It often happens in transverse, still more than in pelvic, presentations, that no part of the child can be felt in an examination in the early part of labor. In arm cases, it is generally the shoulder which is the primary presentation, the arm and hand coming down as the labor progresses. When the shoulder presents, the transverse position of the long diameter of the child frequently keeps it above the brim of the pelvis for a considerable time after the commencement of the dilatation of the os uteri. When the arm or hand is felt, much care should be taken to complete the examination, so as to ascertain whether the hand is descending with the head, or whether the shoulder 420 EARLY RECOGNITION OF ARM PRESENTATIONS IMPERATIVE. engages the pelvic canal. The diagnosis of arm cases is frequently difficult, and we should not give a positive opinion until we can examine satisfactorily through the os uteri. We may sometimes suspect the nature of the case by examining through the anterior wall of the cervix, before the dilatation of the os, but it is better under such circumstances never to give a positive opinion. The diagnosis between the breech and shoulder, the knee and elbow, and the hand and foot, has been given in the last lecture, so that it is unnecessary to repeat it here ; the chief difficulty is in the diagnosis between the elbow and the knee, when both the leg and forearm are bent upon the thigh or arm. In cases of doubt, it is best to bring the hand or foot gently down, when the difference between the upper and lower extremities can easily be made out. No harm is done by this manipulation, either in knee or elbow cases. When there is a suspicion of arm or pelvic presentation, the patient should never be left until the nature of the case is clear ; but this is particularly the case when the arm is the presenting part. It is, as we shall see, of the highest importance that arm presenta- tions should be recognized as early as possible. Perplexing cases do however occur, in which the head presents, in the first instance, but is afterwards converted into a presentation of the arm, in a manner to be referred to presently. These are cases of deformity of the brim of the pelvis. The canses of transverse presentations have been men- tioned when treating of the natural attitude and position of the foetus in utero, and the causes of pelvic presentations. [Also by Dr. Barnes, page 435.] The arm may present because of the death of the foetus ; obliquity of the gravid uterus; contraction of the pelvic brim; violent uterine contractions; twins; and ■ excessive movements of the foetus itself. These are the princi- pal sources of transverse presentations. In the case of a dead foetus, the loss of the adaptive movements of the child and the alteration in the specific gravity of the head are evidently the sources of the frequent pelvic and transverse presentations met with in such cases. In obliquity of the gravid uterus, we can easily understand that the corresponding oblique position of the foetus may lead to the lodgment of the head above the brim and its protrusion into the right or left iliac fossa, while the shoulder descends. We have direct evidence that contraction • ARM PRESENTATIONS WITH TWINS. 421 of the pelvic brim is a cause of arm presentation in cases in which, with slight pelvic deformity, the head presents in the first instance, but the shoulder and arm subsequently descend. Cases of this kind have often been met with several times suc- cessively in the same patient. In these cases the head cannot easily enter the brim; the force of the uterine contractions doubles the neck of the child, and the shoulder, as a smaller part than the cranium, is urged into the pelvis. It is highly probable that irregular or violent contractions of the uterus before or at the commencement of labor may cause shoulder presentations. This explanation is the only one apparently applicable to cases which are met with in which, without pelvic deformity, the same woman suffers in successive labors from the presentation of the child's arm. In these cases excessive and painful movements, which are evidently those of the uterus, are complained of. No doubt in different women different degrees of uterine excitability exists, and we are obliged to look to the mother for the cause, in cases of repeated mal-presentation. Excessive movements of the foetus, and great distension of the uterus with liquor amnii, so as to deprive the foetus of the moulding infiuence of the normal ovoid uterus, are other causes of arm as of pelvic presentations. In twin cases, it frequently happens that one child is delivered with cephalic presentation, and the other with the breech or arm. It sometimes occurs in twin cases that both children descend with arm presentations. The following is a history of what generally occurs in arm cases, when the pelvis is of average capacity, the child living, and of ordinary size, and when no assistance is given: The first stage of labor, as already mentioned, is slow, and the pains are inefficient until the shoulder fully engages the os uteri. After the rupture of the membranes, which may occur at any time, there is usually a pause in the progress of labor. The liquor amnii is quickly discharged, but some time elapses before the presenting part of the child comes to exert full pressure on the os and cervix uteri. When the shoulder and upper part of the body of the child is low in the pelvis before the escape of the liquor amnii, the pains are at once increased in severity, and tlie fruitless efforts at the expulsion of the foetus soon become dangerous both to the child and the mother. The shoulder is the point, as it were, of a large wedge, one side of which is 422 NATURAL DELIVERY ARM CASES. formed by the neck and head, and th'e other by the arm and pelvis of the child. Its passage through the pelvis in this posi- tion is impossible. If the case proceeds, the pressure on the foetus becomes immense, and its long continuance frequently destroys the child by arrest of the circulation in the placenta and funis, or mechanical compression of the body. The danger to the mother is very, great. Either the vaginal discharges be- come offensive, and inflammation and sloughing of the parturi- ent canal occurs; the woman dies of exhaustion, worn out by the long-continued struggle; or the uterus is ruptured, and she perishes in this manner. Probably, at the present time, a case hardly occurs in which a patient suffering from arm-presentation passes on to the extreme catastrophe without some assistance ; but, when rupture of the uterus does not occur, cases are some- times seen which have spread over several days. It may be said, that when the foetus is mature, and the pelvis of ordinary size, death, both to the mother and foetus, is well-nigh inevitable, in cases of arm-presentation, when no assistance is given. In protracted arm cases, it frequently happens that the uterus is exhausted by its exertions before the time of delivery, and that frightful post partum haemorrhage occurs from atony of the uterus. But there are natural modes of delivery in certain cases, and under certain conditions, in arm cases. Denman found that in cases of this kind, when the pelvis was large and the child dead or premature, the long-continued efforts of the uterus were sometimes equal to delivery without danger to the mother. He observed that in some cases the arm and shoulder passed above the pelvic brim during the continuance of the pains, and the body and the pelvis came down, the child being delivered by the breech. This mode of delivery was termed by Denman " Spontaneous Evolution," version, or turning, and the ex- planation of this great obstetrician was received by his contem- poraries. After a time, however, the explanation of Denman was called in question by an accurate observer, Dr. Douglas, of Dublin. This physician observed cases in which, the foetus being immature or dead, and capable of doubling upon itself, the arm and shoulder remained down, but became fixed against the arch of the pubis. The shoulder being fixed against the pubis, he observed the body and spine of the child to become SPONTANEOUS EXPULSION. 423 bent, the nates to descend to the perinaeum, and the lower half of the child to sweep down the sacrum and soft parts of tht» Fid, 120. Commencement of Spontaneous Expulsion. parturient canal, until the breech and inferior extremities were expelled. The other arm then came down, and the head was Fig. 121. Further progress of Spontaneous Expulsion. delivered as in breech cases. Dr. Douglas termed this ma- noeuvre " Spontaneous Expulsion," in contradistinction to the 124 EXPULSION AND EVOLUTION, SPONTANEOUS. " Spontaneous Evolution " of Denman. Other observers cor- roborated the explanation offered by Douglas, and Denman was Fi& 122. Termination of Spontaneous Expulsion. supposed to have been in error when he said that the arm re- ceded before the descent,of the body and breech. Later authors have, however, ascertained that both Denman and Douglas were right, and that in one class of cases the child is born in the manner described without recession of the arm, while in another the arm does not recede, but the shoulders become fixed to the pubic arch, forming a ginglimus or hinge in this direction, while the breech and body sweep down the sacrum and perinaeum. These terminations form, however, the rare excep- tions in breech cases, and though it is necessary to understand them, they must never be expected or waited for in the manage- ment of breech cases. The preceding engravings illustrate the process of spontaneous expulsion, which occurs more fre- quently than spontaneous version. The treatment of arm and shoulder presentations is one of the most important within the range of obstetrics. The con- duct of these cases calls for all the knowledge and judgment of the accoucheur, as his proceedings must vary considerably AID LN ARM PRESENTATIONS. 425 according to the stage of labor and the particular complica- tion of each individual case. It may be said of all cases of arm and shoulder presentation made out at the commencement of labor, that every care should be taken to preserve the liquor amnii from discharge. With this view, the necessary examina- tions should be made as gently as possible, taking care to exert no pressure upon the membranes when they are made tense by a pain. The patient should be kept in the horizontal position, and cautioned against making efforts at bearing down, either during the pains, or in evacuating the rectum or bladder. In cases where the shoulder presents alone, or where the arm hangs in the vagina and the shoulder engages the os uteri, the only remedy when the child is alive and at the full period, is the operation of turning. The earlier this operation is performed the better, unless in cases where the child is so fully engaged in the pelvis, or the uterine actions are so powerful, that means are necessary to relax the uterus, in order to make the operation practicable, and to avert as far as possible the danger of rupture of the uterus, or inflammation of the parturient canal. When the hand and head present together, no great effort at putting up the arm or hand should be made, if the head has not fairly entered the pelvis, as by so doing the head may be pushed aside above the brim, and the case converted into one of purely arm and shoulder presentation. The arm and head form a less for- midable complication than the conversion of such cases into the descent of the shoulder, as the hand and head may be delivered together with safety to mother and child. When the hand and head have entered the pelvis, and present at the os uteri, the hand may sometimes be passed up by the side of the head, in an interval between two pains, and if kept above the head until the pain comes on, it is swept above the brim, and the head descends alone. When the foetus is unmistakably dead, and the shoulder or arm and shoulder present, the operation of turning should be avoided, if possible, on account of the danger the mother incurs by its performance. When the foetus is prema- ture and putrid, it may be brought down, as Dr. Joseph Clarke first suggested, by hooking the crotchet upon the pelvis. When the child is dead, but at the full term, and firmly wedged in the pelvis, the best practice is to eviscerate the chest and abdomen, and then to bring down the pelvis of the foetus by the crotchet. 426 TURNING IN ARM PRESENTATIONS. In the case of dead children at the full term, when the case is made out early in labor, turning is an easier operation, and less troublesome and dangerous to the mother, than protraction of the case, and evisceration and extraction. In rare cases, when the pelvis is very capacious, and the action of the uterus powerful, and the foetus small, or dead, or premature, the accou- cheur may sometimes be called, when, the shoulder and arm being felt at the pubis, the ribs and body of the child occupying the lower part of the pelvis and pressing upon the perinaeum, and some advance of this part of the child occurring at each pain, it is evident that the spontaneous expulsion of Douglas will terminate the delivery. Sometimes this spontaneous expulsion of the child takes place with great rapidity. I was once sum- moned to turn a child, at no great distance from my own house, but before I arrived the woman had been delivered spontane- ously. In rarer cases the arm and shoulder will ascend, and the nates come down, under the influence of the pains, as in the spontaneous version or evolution of Denman. As regards the great and most common procedure necessary in transverse pre- sentations—namely, turning, the circumstances of the operation are very much varied, according as the amnion is ruptured or not; or the presenting part high or low in the pelvis; and the length of time which has elapsed in these cases between the com- mencement of labor and the performance of the operation. In transverse cases, auscultation of the fcetal heart is imperative, as upon the life or death of the child may depend the alterna- tive of evisceration or turning. In many arm and shoulder cases, the child has been dead for some time before the com- mencement of labor, and the cuticle is falling off or the limb is putrid. In others, a loop of funis is down with the arm, and its pulseless and flaccid state informs us of the death of the foetus. The peculiarities incident to turning in transverse cases under every variety of circumstance will have to be considered when we come to the operative part of the present course. It may be mentioned, that when the arm presents in the case of the second child in twin cases, the same treatment is to be followed as though a single child had presented with the arm. The opera- tion of turning is generally easy in such cases from the smallness of the child and the dilatation of the passages. No doubt in arm cases the easiest and the most difficult conditions for the STATISTICS OF ARM PRESENTATIONS. 427 operation of turning are met with. In a case where the liquor amnii remains undischarged, and the arm is found at the os uteri, the foetus is moved as easily as a boat in water, the hand of the accoucheur can be introduced with comparative ease, and turning is a simple operation. But when the patient has been in labor, and the liquor amnii discharged, it may be for twenty- four, forty-eight, or more hours, the shoulder is jammed into the pelvis, and held as if in a vice. It is most difficult either to introduce the hand, or to move the child, and turning is one of the most difficult, if not the most difficult, operation in obstetrics. The mortality to the mother and the child, but particularly the child, under these circumstances, is very great. Dr. Lee, in his " Clinical Midwifery," relates fifty-nine cases, and records the death of the mother in eleven, and the death of the child in thirty-two cases. These cases were amongst the most severe that could be met with in consultation practice; and such results should imprint upon accoucheurs the necessity of an early diagnosis, and prompt action in this form of dystocia. Dr. Fleetwood Churchill has collected the statistics of 112,140 cases, in which the superior extremities presented 484 times, or, taking the average, once in 231f cases. In 242 cases of presentation in which the results to the mother and child were recorded, 127 children were lost, or rather more than 1 in 2, and 26 mothers died, or about 1 in 9. All statistics tend to show that in this complication, more than in any other, danger both to the mother and child increases with the prolonged duration of labor. LECTURE XXIX. PLACENTAL PRESENTATION. Gentlemen :—In the present Course of Lectures I have not attempted to make any rigorous classification of the varieties of difficult or complicated parturition. The subject does not, indeed, admit of arbitrary arrangement. My object has been not to abandon method entirely, but to group similar conditions of labor together, so that mutual light may extend from one subject to another, by successively treating of those normal and morbid states which possess certain points of resemblance. Nothing can be more natural than to group together the dif- ferent modes in which the foetus presents and passes through the pelvis. But we now come to the subject of Placenta Praevia, which is related both to the varieties of presentation, and in its most dangerous symptom, to the different forms of haemorrhage. Still, as it is undoubtedly one of the forms of presentation, and as its attendant haemorrhage is peculiar and in many respects distinct from ordinary flooding before or after delivery, I have preferred to consider it at the present time, after having treated of the different forms of presentation belonging to the head, trunk and extremities of the foetus. The placenta may be attached over the whole of the os and cervix uteri, or it may be implanted over some part of the mar- gin of the os, so as only partially to occupy the aperture. The causes of placenta praevia have not been determined. It is pro- bably produced by the impregnation of the ovum after it has descended to the upper part of the cervix uteri, this beino- the last point at which the ovum retains its capability of impregna- tion and attachment to the uterine surface. The placenta may be attached to any part of the body of the uterus between the cervix and the fundus, but unless it encroaches upon that part of the cervix concerned in the development of the lower seg- CAUSE OF PLACENTA PREVIA. 429 ment of the uterus, or the dilatation of the uterine aperture at parturition, no ill consequences ensue. Up to the fifth month, the development of the ovum proceeds in the ordinary manner in placenta praevia, and if abortion occurs before this time there is nothing which indicates the site of the placenta. After this date the development of the cervix proceeds, and, in its expansion, partial separation of the placen- ta from its attachment is prone to occur. This separation is attended by the frightful and sudden haemorrhages which char- acterize placental presentations. The irritation of the uterus by the placental attachment to the cervix, and the separation which occur, often lead to abortion or to delivery before the natural term in these cases. Sometimes patients go on to the full term when suffering from this complication, without the occurrence of haemorrhage before the commencement of labor. The symptoms of placenta previa are sufficiently distinc- tive. Occasional haemorrhage occurs, generally between the seventh month and the end of gestation. The discharge com- monly takes place suddenly, without pain, and ceases after a while, or the drain may continue for a considerable time. The nearer the patient is to the full term, the more violent is the loss of blood. The gush may take place after some exertion, or when the patient is following her usual avocations, or when she is asleep. The loss is sometimes so sudden and so enormous, that the woman is dead before the medical attendant can be summoned. Generally, there are several sudden losses to a less extent, before the advent of labor. Flooding may recur at vari- able intervals, of a few days, a week, a fortnight, or it may break out at the dates of the catamenial periods. Placental presentation should always be suspected, whenever haemorrhage occurs in the latter part of pregnancy. Sometimes labor comes after the discharge; at others, there are no traces of uterine action until after several attacks of flooding. There are no sen- sations belonging to the patient herself which indicate malposi- tion of the placenta, but the uterine soufflet is heard in these cases with most distinctness in one of the iliac regions, or the hypogastrium. When we examine internally, if the os uteri has dilated, the soft mass of the placenta can be felt between the finger and the presenting part of the child. The soft pla- centary layer may be felt in the entire field of the os uteri, or 430 HEMORRHAGE OF PLACENTA rRJEVIA. occupying only one margin of the os. If the flooding has been very severe, a portion of the placenta, or the greater part of the organ may be felt protruding through the os uteri. When the os is quite closed, the placenta can sometimes be distin- guished through the walls of the expanded cervix, particularly if the head presents, and the placenta lies between the finger and the foetal cranium. In the case of breech or shoulder presenta- tion, the detection of the placenta is more difficult. If the os uteri should be so high up in a case of suspected placental pre- sentation, as to be beyond the reach of the finger, the whole hand should be carefully passed into the vagina, so as to enable us to reach the os and make the necessary examination. Fatal results have often happened from inattention to this point. There is hardly any other critical emergency in midwifery in which an early diagnosis and prompt treatment are of such importance. The separation of the placenta may be small in extent, or the whole or nearly the whole of the organ may be detached. What usually happens is, that at each recurrence of haemorrhage, small portions of the placenta are detached, up to the time of labor. Before the commencement of labor, and when no symp- toms of abortion are present, the cause of detachment is the developmental expansion of the cervix uteri; but when labor has set in, the active dilatation of the os and cervix effects the placental separation. The most violent and dangerous cases are those in which little or no haemorrhage occurs unto the full term, when sudden and extensive detachment takes place, the utero- placental vessels having reached their full development. The woman may, under these circumstances, be deluged with blood, and reduced to the utmost extremity of danger in a few minutes. Where partial and repeated separations occur, the uterine ves- sels which have been laid open contract, and the blood coagu- lates in that part of the placenta which has been separated. This process may be repeated several times before the coming-on of labor, and while the placenta is only partially attached over the os uteri. In rare cases it happens that the whole of the cer- vical portion of the placenta is detached in this manner, and little or no haemorrhage occurs at the time of labor. In 'other cases of partial placental presentation the cervical portion of the placenta is completely detached at the time of labor and no serious haemorrhage occurs after the first outbreak. Still more TRUST TO NATURE IN PLACENTA PRJEYIA. 431 rarely, when the uterine action is very powerful, the pelvis capa- cious, the foetus small or of moderate size, and the patient mul- Fro, 123. Entire placenta prcevia. tiparous, the whole of the placenta is detached, and the foetus and membranes expelled with such rapidity that no dangerous loss occurs. These cases have led some to imagine that in entire placenta praevia, Nature may be trusted more than she is. But the conditions are so unfavorable to the safety of the patient, that such reliance is worse than on a broken reed. This conjunc- ture offers no place for a Fabian plan of treatment. To wait, is generally to kill. In case of placenta praevia we have the cir- cumference of the os and cervix studded with large vessels, the mouths of which gape widely open as the placenta separates and the os and cervix dilate. And this separation and dilata- tion must occur. There is no escape from them and the slow and gradual way in which the preparation for the exit of the foetus is generally made, and which in ordinary cases tends so much to the safety of mother and child, is here their destruction. The haemorrhage in cases of placenta praevia has been called " un- avoidable " haemorrhage, by way of distinguishing it from 432 MATERIALS FOR PLUGGING THE VAGINA. haemorrhage from the fundus uteri occurring before labor, which has been termed " accidental." In the one case separa- tion and haemorrhage may, in the other they must, occur before the completion of delivery. The chief methods of treatment followed in cases of placenta praevia are—1. The use of the plug, or tampon. 2. Puncturing the membranes. 3. Turning the child. 4. The partial or the entire separation and extraction of the placenta. I propose to point out in detail the cases and conditions in which these several modes of practice are applicable. Plugging the vagina is adapted to cases in which, after the first loss, a continuous drain, varied by slight eruptions of blood, is going on, particularly when this occurs at the sixth or seventh month. By plugging the vagina with moderate force, the lower segment of the uterus is compressed between the plug and the contents of the uterus, and an impediment is offered to • the escape of blood, and coagulation of the blood effused is promoted. Care must be taken that the plugging be not too forcible, otherwise uterine contraction and further separation may be excited by the irritation of the plug. The best methods of plugging the vagina are by introducing strips of lint, pieces of sponge, or a silk handkerchief, dipped in vinegar and water, or iced water. Pieces of ice, wrapped in lint may be intro- duced. There is a great advantage in the sponge-plug— namely, in its expansion from absorbing the blood, or the secretions of the vagina. But this is, to a great extent, counter- balanced by the rapidity with which sponge, from the animal matter it contains, becomes foetid in the vagina. It cannot, on this account, be allowed to remain in the passage more than a few hours. It is, therefore, the best temporary plug, but it is not adapted to cases in which continuous plugging is required. [The colpeurynter, already alluded to on page 180, should not be forgotten as affording speedier and more efficient relief than any other form of plug, and moreover, may be easily withdrawn and replaced as, required.] As an ordinary plug, nothing exceeds in utility strips of lint, introduced one after another until the vagina is filled up. Even in plugging with lint or a silk handkerchief, the plug requires to be changed from time to time, as, whatever the plug, the retained blood and discharges, to which air is necessarily admitted, have a tendency to become TREATMENT OF PLACENTA PREVIA. 433 rapidly foetid. Whatever the treatment adopted in placenta praevia, one precaution should always be adopted—namely to keep the patient in the horizontal position, with the pelvis some- what raised. The temperature of the room should be cool and equable, and the diet light and unstimulating, except when the patient is suffering from the direct effects of loss of blood. Under these circumstances, brandy, ammonia, and beef-tea may be administered freely. I do not believe that in unavoidable haemorrhage, internal astringents, such as gallic acid or the ace- tate of lead, are of more than the slightest use, and they tend to divert the attention of the practitioner from more important measures. With this exception, the treatment of placenta praevia in the fifth or sixth month, when the os uteri is undilated, and the flooding not dangerous in extent, is hardly distinguish- able from flooding in ordinary abortions. When haemorrhage has once occurred, the patient should be kept as quiet as possible, lest a further separation should be produced. Puncturing the membranes and evacuating the liquor amnii in placenta praevia is a practice of very ancient date. It is occasionally useful, and is adapted for cases in which the haemorrhage is not of the most alarming character, where the os uteri is either closed or only dilated to a slight extent, where the pains of labor have already commenced, or where it is con- sidered advisable to induce premature labor in this manner, where the liquor amnii is in large quantity, where turning is impossible, and where the child being alive, it is judged best not to attempt the separation of the placenta. This operation is preferred in cases of partial attachment of the placenta over the os, where the membranes can be ruptured either by the fin- ger, or a probe or trocar at the part free from placenta ; but it has sometimes been performed with the effect of arresting the haemorrhage, through the placental mass in cases of complete attachment over the os uteri. Puncturing the membranes in placenta praevia does not arrest flooding simply from diminish- ing the size of the uterus and exciting contraction, but by les- sening its size and vascular supply, and bringing down the head or presenting part of the child, so as to act as a plug to the pla- cental site. The disadvantages of puncturing the membranes are, that turning is thereby rendered difficult, and the risk of sacrificing the child is increased. In cases where the labor is 28 WHEN TURNING IS PROPER IN PLACENTA PREVIA. premature, and the child non-viable, these objections do not apply at all; nor in cases where the child is dead, as craniotomy could then be performed. It is, however, questionable whether in these cases the extraction of the placenta should not be pre- ferred. In my opinion, turning is the great operation in placenta praevia, when the child is living and viable—that which, if per- formed at the proper time, affords the greatest chances of safety both to the mother and the child. But there are circumstances in which turning is the best practice when the safety of the mother alone is concerned, the child being already dead. The conditions favorable to turning are, a dilated or dilatable state of the os uteri, the retention of the liquor amnii or a moderately relaxed state of the uterus, a pelvis of average capacity, the absence of dangerous exhaustion, or a temporary cessation of the haemorrhage. If the placenta be attached to one side of the uterus, the hand should be introduced on the side opposite to the placental site; or if it extends over the whole os, the hand should be passed in the direction in which the attachment is least considerable, or when the separation has already taken place. The advantages of turning are, that without materially increasing the danger of the patient, and in a very short space of time, the feet and body of the child may be brought down so as to act as a tolerably efficient plug to the os and cervix ^ uteri. During the early part of the operation, the hand and arm of the accoucheur form a tampon. Turning is generally easy in placenta praevia, at the full term, as compared with other cases in which it is required, because the con- tractions of the uterus are commonly less powerful than usual. The flooding itself tends to dilate the os uteri, and to weaken uterine action. It is, therefore, a less severe operation to the mother than in many other cases in which it is called for. This is particularly the case in multiparous women. As regards the state of the uterus, primiparous women, as in other cases requiring turning, offer greater difficulties than women who have borne children. When the operation of turnino- is per- formed early, the proportion of mothers saved is large, and a ■ considerable number of children are born alive. Turnino- should always be performed in placenta praevia, when it is coi> sidered advisable, the instant the operation is rendered practica- DECISION IN PLACENTA PREVIA. 435 ble by the condition of the os and cervix uteri. In cases where the os uteri has been dilated for many hours, sufficiently to admit of turning, and blood or strength has been lost in the interim, we should blame, not the operation, but the delay, for a great proportion of the fatality to the mother and child. In some cases of partial placental presentation, the head may be so low that the use of the forceps will be preferable to turning; or this operation may become necessary after the spontaneous or artificial expulsion of the placenta. In other cases, as when the head is low, and the child dead, or when the pelvis is deformed, craniotomy may be called for. Dr. Radford has advised the use of electricity, in connection with the other methods of treatment in these cases. [Perhaps the greatest element requisite for an accoucheur is decision. He should be able to recognize what is possible and what impracticable, particularly in the form of trouble here under consideration, he should early know what he can do, and what he cannot effect. In a case to which I was recently called in consultation, the woman had haemorrhage for some twenty hours continuously, beside haemorrhages a month, two weeks, and a week previously. She was reduced to so low an ebb that I questioned if she could survive the loss of a single wine-glass full more of blood. I dared not venture the dangers from delay, and fresh haemorrhage consequent upon turning, but the os not being dilated so as to use forceps, being two inches in diameter, I perforated the head and delivered with great rapidity, without the loss of a drop of blood, and saved a beau- tiful young lady from "the grave, whither it was supposed by her attending physicians she was inevitably doomed. In a similar case, in the care of a gentleman who found fault with this opera- tion, by attempting too much to save an already ex-sanguine child, after thrice failing to deliver w.ith the forceps, then turn- ing, and finally opening the head of the child to effect its delivery, operations lasting more than half an hour with still continuing haemorrhage, the mother died in ten minutes after.] I have now to refer to the artificial extraction of the placenta before the birth of the child, which has certainly been one of the most prominent points in obstetric practice during the last ten or twelve years. It is one the settlement of which is of great interest, as nothing can be more unsafe than 436 SIMFSON ON DETACHING THE PLACENTA. halting between two opinions upon such a subject. From an early period, it had been remarked by accoucheurs that cases of unavoidable haemorrhage were occasionally met with, in which the placenta was expelled spontaneously before the birth of the child, and that the haemorrhage was arrested by the separation of the placenta. The first person who seemed to have pointed out the deduction of a rule of practice from such cases was Mr. Chapman, of Ampthill. The placenta was removed in some cases of placenta praevia, by Mr. Kinder Wood, of Manchester, and subsequently by Dr. Radford. Probably, cases have always occurred in which accoucheurs, finding the placenta loose in the vagina, or almost entirely detached, have removed it. Dr. Simpson took up this subject in 1844, and, with his usual ability and force, pointed out what he considers the advantages of this operation, the principles upon which it is and the cases to which it is applicable. The tenor of Dr. Simpson's earlier writings was such as to lead to the belief that he wished to supersede in great measure the operation of turning, by the separation and extraction of the placenta. This impression has v continued to a great extent up to the present time, and it is upon this impression chiefly that its opponents have attacked and denounced the operation. In one of his latest publications on the subject, in The Lancet, 1847, vol. i., he has corrected this, and insists upon the limitation of the extraction of the placenta to cases " when the other recognized modes of management were insufficient or unsafe, or altogether impos- sible of application," or when the old methods of practice " were attended by extreme hazard or extreme difficulty." Dr. Simpson combined with his advocacy of this practice an exposi- tion of his views as to the source of the haemorrhage in pla- centa praevia, which met with great opposition. Dr. Hamilton advocated the doctrine that the haemorrhage in placenta praevia " proceeds from the separated portion of the placenta more than from the ruptured uterine vessels." Dr. Simpson indorses this view to the full extent, and I suspect it is this, as much as the rule of practice itself, which has excited the opposition which has been manifested. According to this hypothesis the blood lost in separation of the placenta flows from the placental cells the supply to these cells being kept up by vessels supply in o- the ■ undetached portion of placenta. It is supposed that as the SOURCE of the hemorrhage of placenta previa. 437 separation proceeds, the veins of the uterine surface from which the placenta is detached, are closed so as to prevent any retro- gressive haemorrhage from the uterus. Dr. Simpson's theory of the source of the haemorrhage, upon which he to some extent rests his practice of separating the placenta, is, I believe, altogether untenable. No proofs of the escape of the great quantities of blood lost in these cases, from the placental surface, can be given. The theory mainly rests upon the anatomical arrangement of the uterine arteries, the placental cells, and the openings upon the placental surface. No doubt there is an unobstructed channel for the flow of blood from the curling arteries, through the placental cells and the openings found upon the placental surface, when this has been separated from the uterus. But there are, as it appears to me, valid reasons why we should believe that the sudden and great gushes of blood poured out in placenta praevia do not escape in this way. The uterine arteries are of comparatively small cali- t bre, and the openings upon the placental surface are neither large nor numerous. Supposing one-half of the placenta to be detached, it is highly improbable, I should almost say impos- sible, that the profuse loss frequently met with in these cases could come from the uterine arteries entering the undetached portion of the placenta, even if they were all discharging blood simultaneously. In the cases of profuse loss which sometimes occur, when only a small portion of the placenta is detached, it is equally difficult to suppose that the blood could escape from the openings met with on a square inch of placental surface. There are, on the other hand, valid reasons for believing that the uterine veins are the real sources of haemorrhage in placenta v praevia. The size of the venous openings, the valveless state of the uterine veins, the channel being unimpeded from the right auricle to the open mouths of the sinuses, furnish anatomical arguments in favor of this source for the flow of blood which are stronger than those derived from the anatomical arrangement of the uterine arteries, and the placental sinuses, in favor of the opposite view. Then we have the facts connected with post- partum haemorrhages. The only haemorrhages comparable for suddenness and extent to the losses in placenta praevia are those , which occur after labor, and the expulsion of the placenta, in cases where it has been attached to the fundus uteri. Here 438 is the bleeding from the placenta or uterus ? there can be no question but that the haemorrhage takes place from the open mouths of the uterine veins. I have not observed any difference in the color or character of the blood in post-par- tum haemorrhages and those caused by placental presentation, and the weight of evidence is in favor of the venous character of the blood lost in placenta praevia. It is noticed that in this form of flooding the loss is increased during the pains, as it is believed, by the enlargement of the uterine openings by the dilatation of the os and cervix uteri, whereas, in haemorrhage / from the fundus, the flow of blood is arrested during the con- tinuance of pain and contraction. When the separated portions of placenta have been examined, it has been found that the sinuses and cells have been filled with coagulated blood. In some cases, in which the placenta has been detached and ex- pelled artificially or spontaneously, flooding has occurred after the expulsion of the placenta. Here the blood must have been in great part from the uterine veins, yet the flooding presents no difference to that occurring from the partial separation of the placenta. The inference from all these facts appears to be, that in the haemorrhage from placenta praevia the blood escapes in great part from the uterine surface, and not from the maternal ^ surface of the placenta. There can be little doubt that some blood must exude from the surface of the placenta in cases of partial separation, whether the placenta be attached to the fun- dus or cervix; but I contend that this is not the chief source of flooding in placenta praevia. While I thus take exception to Dr. Simpson's theory of the nature of haemorrhage in placenta praevia, I do not question the correctness of the fact upon which he lays so much stress- namely, the frequent, and indeed common," arrest of the haemor- j rhage on the entire detachment of the placenta. Dr. Simpson's theory does not appear to me to be necessary to the explanation of this matter. In my work " On Parturition," I pointed out that tlie separation of the placenta furnishes a source of irrita- tion which excites the uterus generally, and the muscular strue- " hire at the site of the placenta especially, to contraction and that in this way haemorrhage was prevented. This is probably the reason why, in twins with separate placentae, there is frequently no haemorrhage between the expulsion of the first placenta and the birth of the second child. It is reasonable to EXTRACTION OF THE PLACENTA ADVISED. 439 suppose that the same thing occurs in placenta praevia, after the separation and extraction of the placenta, in the intervals which occur between the pains. The tendency to haemorrhage from dilatation of the orifices of the veins during the pains is is corrected by the descent of the head or presenting part, and mechanical compression of the uterine walls. Dr. Simpson unequivocally demonstrates that in a great num- ber of cases recorded by various authors, both before and since the publication of his views, the placenta has been detached and the haemorrhage arrested. There can, indeed, be no ques- tion upon this point. Those most opposed to Dr. Simpson, Dr. Robert Lee, for instance, record cases in which the haemorrhage ceased after the spontaneous expulsion of the placenta. The cases to which, in his most recent writings, Dr. Simpson would advise separation and extraction, are those in which the evacua- tion of the liquor amnii is of no avail, when the state of the j patient is such as to call for interference, but where turning, or other measures of delivery, are impracticable, from rigidity, or non-development of the os and cervix uteri, or distortion of the *" pelvis. He would also employ it in the case of dead, prema- ture, or non-viable children, particularly when the uterus has contracted, or is so imperfectly developed as not to admit of turning. It is questionable if rigidity can be a valid plea for this operation, except in very rare cases. When the os uteri is sufficiently open to allow of the admission of the fingers for the purpose of separating the entire placenta, there will generally be room enough for the admission of the hand. I believe the separation and extraction of the entire placenta the best practice in those cases in which it is attached all round the os uteri, and in which the exhaustion is so great as to render some more rapid , attempt at assistance than the operation of turning imperative. In some of these cases the patients would be killed by turning, if the haemorrhage were going on simultaneously with the operation. The extraction of the placenta offers a means of arresting haemorrhage, and after a short rest the patient may be suffi- ciently rallied to bear turning ; for it must be remembered, that in many of the cases in which the placenta has been extracted ^ artificially, turning has been necessary to complete the delivery. In all cases where the child is alive and viable, delivery should be effected, by turning or the forceps, as soon as possible after 440 STATISTICS OF PLACENTAL EXTRACTION. the extraction of the placenta, if the state of the patient is such as to bear the operation. Extraction may be sometimes useful in cases where turning is impossible, as in cases of contraction of the uterus or pelvic deformity, and when the removal of the placenta may arrest haemorrhage and facilitate the operations of turning, craniotomy, or evisceration. It may also be prac- tised in some cases of dead or premature children, when the haemorrhage is going on, and turning is difficult from any cause. When the flooding is not profuse, and when the uterus is roomy and the waters undischarged, the extraction of the placenta be- fore the child offers no great advantage. The whole subject has been ably handled by Dr. Chowne, and Dr. Fleetwood Church- hill gives a very candid exposition of the disadvantages of the operation. It is necessary to refer to the statistical arguments which have been advanced in favor of the operation. Dr. Simpson has given a table of 654 cases, collated from various authors, from Mauri ceau to the present day, in which the treatment consisted of turning, etc., the child being extracted before the placenta. This he contrasts with another table of 141 cases, in which the placenta was removed or expelled before the child. In the 654 cases, 180 mothers, or 1 in ST%, were lost. In the 141 cases, the maternal mortality was 10, or only one in 14, which apparently gives a very large balance in favor of the extraction of the pla- centa before the child. But it has been argued by Dr. Barnes that we cannot fairly suppose cases in which the placenta is j extracted artificially will prove as favorable as those in which it has been detached and expelled without assistance. The cases in which the placenta is expelled by the natural efforts are those in which the pains are powerful, the placenta being expelled suddenly and the child speedily born. In the case of artificial detachment and extraction, no assistance from the uterus can be <- reckoned on. The difference is very great between the spon- taneous separation and expulsion and the artificial detachment and extraction of the placenta. The published cases of extrac- tion of the placenta are too few to found upon them any precise conclusions; and it must also be remembered that the advocates of any novel mode of practice are more prone to publish snc- > cessful than unsuccessful cases. The statistics of Dr. Radford of cases in which the placenta was removed by the hand are SPONTANEOUS EXPULSION OF THE PLACENTA. 441 not so favorable, as regards the mother, as those of Dr. Simp- son. By the ordinary methods of practice, rather more than half " the children are lost; and Dr. Simpson attempts to show that the mortality is scarcely more than this when the placenta was extracted before the child. He gives a table of 141 cases: of these the child was saved in 33 cases ; in 79 cases it was born dead ; in 1 the child was anencephalous, and died shortly after birth ; in 28 cases, the result, as regards the child, was not stated. But such a state of mortality cannot be hoped for from artificial extraction. In many of the cases of spontaneous ex- pulsion, the foetus, membranes, and placenta are expelled by the same pain. Dr. Simpson, as Dr. Fleetwood Churchill . observes, has only recorded one case of the child being born alive when the interval after the removal of the placenta was t more than ten minutes. Dr. West collected 17 cases; but in 16 of them the children were lost. If this frightful rate of foetal mortality should be preserved, it must go far to prevent the adoption of extraction in any but the most unpromising cases. In 1S47, Dr. Barnes enunciated the principle, that a partial separation of the placenta might, in certain cases, be sufficient to arrest the haemorrhage, and at the same time afford a chance of safety to the child. In a recent paper on this important sub- ject, an abstract of which was published in The Lancet in January 1858, Dr. Barnes recommends a partial detachment of the placenta in cases where it is partially attached to the cervix, or where it is implanted in its whole circumference. His method is to detach that portion of the placenta attached to the - cervix, after which he believes that no further separation is produced by the uterine pains, and the haemorrhage entirely ceases. The portion of the placenta attached above the cervix is left, and remains as a medium for the supply of the foetus. Dr. Barnes has collected a large amount of clinical facts and ex- perience bearing upon this subject, [which he has published since these lectures were delivered, and may be found in extenso in the London Lancet reprint for Sept., Oct., Nov. and Dec. 1857.] Nothing could be more valuable than the establishment of a mode of practice which should diminish the danger to the mother, and increase the chance of safety to the child. In Ger- many, several physicians have done Dr. Barnes the honor to 442 DANGERS OF PLACENTA PREVIA. claim and contend for originality in advancing the the partial separation of the placenta; but there Fi&. 124=. Varieties of placental attachment. E, E, Fundal Placenta. D, D, Lateral Placenta. P, F, C, B, Latero-cervical Placenta. A, B, B, F, Seat of cervico-orificial, or central Placenta. A, E, Line of boundary between normal and previal placental attachment, and consequently of spontaneous placental detachment, during expansion of cervix. doubt the principle was clearly expressed by him nearly ten years ago. The preceding engraving, executed from a drawing by Dr. Barnes, indicates the various positions in which the placenta may be attached. (Fig. 124.) The danger as regards the mother, in placenta praevia, arises chiefly from the direct or secondary effects of loss of blood, and from injuries done to the passages by operative proceedings. Dr. Tyler, of Dublin, has related a case, in which traumatic \J tetanus followed upon placenta praevia. Uterine phlebitis is frequently met with after placenta praevia in cases where the patient survives delivery. Out of sixty-four cases, Dr. Lee records that phlebitis occurred in six cases. As phlebitis BARNES ON PLACENTA PREVIA. 443 occurs in cases where turning has not been performed, or where the operation gave little or no pain, it is probable that the disease of the veins may be caused by their being bathed in the uterine discharges as they pass the os and cervix uteri. The special dangers to the child arise from asphyxia, the result of the flooding, or pressure on the cord in turning, etc. [The opinions of Dr. Barnes, which are in the papers already alluded to, fully enunciated and fortified by cases which tend to sustain his position, are substantially as follows. As they are so important in their claims, they are here given quite in extenso, and as nearly as possible in his own words: If we watch attentively a case of labor in which the placenta presents—I mean of course such a case as admits of simple watch- ing, that does not call for obstetric interference—we shall observe that as soon as the longitudinal muscular fibres of the womb have begun to contract so as to pull back the lower segment from the central point represented by the os uteri internum, a certain amount of detachment of the placenta from the part nearest to the os takes place ; owing to the periodical and sudden nature of the uterine contraction, this detachment is also sudden; the sudden detachment is attended by a sudden escape of florid blood ; the contraction ceasing, the flow of blood also, for the most part, ceases entirely, or subsides greatly ; with the returning contraction, there is a fresh detachment of placen- ta, and another gush of florid blood ; the contraction at an end, the flow of blood again subsides. This order of events recurs in the same succession, perhaps several times. But, at last, if the child be not first extruded, a stage of labor arrives when the recurrent contractions of the womb do not entail any further flooding J the pains return in their usual course with their usual strength, and with their usual effect of further dilating the os uteri, and forwarding the labor; but there is no more hemor- rhage. The labor is resolved into a natural labor, and may be safely concluded by the natural powers. Now this history, true to nature, is diametrically at variance with the still received dogmas, that the haemorrhage is the v- necessary result of the expansion of the os uteri, and that there is no safety but in delivery. 444 PLACENTAL LIMIT LIABLE TO DETACHMENT. It is not, then, the separation of the placenta which secures immunity from flooding, but the contraction of the womb. This figure is a diagrammatic view of the progress of detachment of placenta. It is cast off in • zones or rings, if the case is one of placenta centralis ; and in segments of rings, if one of cervico- orificial placenta. At A, A, the dilatation of the os involves no further detachment of placenta. There is, then, an anatomical, a physiological limit to the ex- tent of placenta liable to detachment during the expansion of the womb. This is why, after a certain stage of the labor, no fresh bleeding surface is exposed. But how is the bleeding stopped from that part of the uterus already bared of placenta ? By precisely the same mechanism as that which stops the flooding after normal detachment of the placenta from its normal seat at the fundus. The longitudinal muscular fibres of the lower seg-^ ment must contract to pull open the mouth. Expansion, dilata- tion of the mouth, is contraction of the cervix. This contrac- v tion, by shortening the cervical portion of the' womb, casts off the placenta, and exposes the ruptured mouths of the utero-pla- cental vessels. The first effect is, bleeding. The second is, to stop the bleeding. The contraction goes on either actively, or passively and tonically, in most cases ; and this further contrac- tion constricts the orifices of the vessels—closes them: it is haemostatic. If haemorrhage be renewed, it does not proceed, except under circumstances of excessive muscular relaxation__ the " passive haemorrhage " of Dr. Chowne—from the surface bared by the preceding active contraction : it proceeds from a VARIETIES OF PLACENTAL ATTACHMENT. 445 fresh zone or arc further from the os, bared of placenta by another contraction. This zone or arc is, in its turn, in like manner sealed; and there is another pause in the flooding. Zone after zone is thus bared by recurring contractions, and successively sealed up until that physiological limit, that line of ' demarcation between normal and abnormal placental implanta- tion, the boundary-line of placental detachment, which I claim , to have discovered, has been reached. This zone attained, the labor is a natural labor ! At this point of our inquiry we may usefully enumerate the the varieties of seat of placental attachment. To illus- trate this point, I have constructed a diagram. (Fig. 124.) The placenta may be attached to the fundus or upper zones of the uterus—fiundal placenta ; it may be seated on the middle zones —lateral placenta ; it may encroach downwards upon the cer- vical zones—latero-cervical placenta; or it may grow entirely over the inferior pole, rising on all sides so as to occupy the cer- vical zones—the cervico-oriflcial or central placenta. (Fig. 123.) The fundal and lateral placentas are not, unless under very exceptional circumstances, liable to detachment, or to lead to flooding, before the birth of the child. The latero-cervical and ^ the central placentas are, however, so liable. The extent to which this liability goes is greatly affected by the extent to which the encroachment takes place withing the cervical zones. In this case there may be little or no haemorrhage; but should the encroachment proceed further down, the danger of haemor- rhage would much increase. There are cases of flooding before the birth of the child, in which no placenta can be felt, and ^ which are yet strictly cases of placenta praevia. How, it may be asked, do we get evidence of this ? Nothing is more sim- ple. The following case shows one kind of proof: On the 13th of May, 1852, my assistance was required by one of the midwives of the Western General Dispensary. * A poor woman, weakened by poverty and hard work, having had two children at full term and of full size, wras in labor at nine a.m. For two days previously she had had haemor- rhage, which was still going on. The head was low in the pelvis and lying in the first position, and there appeared to be sufficient room; it had, according to the midwife, been in 146 EVIDENCES OF CENTRAL PLACENTA PREIVA. the same position for four hours without any advance. The pains had ceased altogether. Pulse feeble; face pale ; great exhaustion, anxiety, and depression of mind. Fearing that further haemorrhage might be fatal, I determined on delivering by forceps. Whilst waiting for the instrument, I directed the midwife to give an enema. I comforted the patient by assur- ance that she would do well. Almost immediately after, effective pains returned, and the head was expelled in an hour. No further haemorrhage. Child still-born. Lt appeared to me that the uterine contractions were arrested in the first instance under the influence of anxiety and terror. The midwife, before sending for me had sent for Mr. Cholmeley and Dr. Babington (she was a patient of Queen Charlotte's Hospital), and more than two hours had been thus lost. My arrival and assurances restored her confidence; and under the J beneficial influence of that feeling the uterine contractions returned. The decidual surface of the placenta presented numerous specks of osseous deposit; the margin of the placenta presented large fresh coagula of dark color in the substance, and very large fresh coagula were attached to the very edge, and had evidently proceeded from a rupture of the circular venous channel which courses round the placenta. It is this presence of coagula in the margin of the placenta which proves that it had been detached during labor, and that it had encroached upon the cervical region of the womb. In cases of this kind it is often remarkably well seen how -V dependent the haemorrhage is upon the inactivity of the womb, and how completely contraction checks it. Another proof is very interesting. I believe it was first ex- plained by Levret: "Lorsque le placenta est attache dans le fond de la matrice, centre sur centre, non seulement le cordon ombilical est an centre du placenta, mais meme les membranes se dechirent dans ' leur milieu a une egale distance, pour ainsi dire, de tous ses bords ; et lorsque le placenta ee trouve devie" vers les parois de la matrice, outre que le cordon suit et marque le deo-re" de cette deviation, les membranes se dechirent en meme raison__c'est-a- dire, d'autant plus pres de l'un des bords du placenta que cette deviation est grand. Si done le placenta est attache assez bas dans un endroit des parois de la matrice pour que le cordon se RENT OF TUE MEMBRANES--WHERE. 447 trouve implante* sur le bord, ce sera sur ce meme bord et dans ce meme point que les membranes se dechireront." I have made the following sketch to illustrate this position. Recently this subject has been experimentally examined by Dr. Yon Ritgen. He found that the bag of membranes burst at the edge of the placenta in 22 cases ; it burst at one inch from the edge in 8 cases; between one and two inches in 12 cases; between two and three inches in 16 cases ; three inches in 5 cases ; between three and four inches in 4 cases ; at four inches in 6 cases; between four and five inches in 8 cases; at five inches in 3 cases ; at six inches in 6 cases ; and at eight inches in 3 cases. It follows, that since the distance of the edge of the placenta from the rent is absolutely decisive as to the distance of the edge of the placenta from the os uteri, that the edge of the Drawing showing how the seat of rent in the membranes indicates the seat of attachment of tho placenta to the uterus. placenta rested on the os uteri in 22 cases, and was within one inch in 32 cases, and so on. This proves that the placenta 448 CROSS-BIRTHS WITH PLACENTA PREVIA. has commonly a much lower seat than has hitherto been be- lieved. This frequent latero-cervical attachment of the placenta has other important bearings in obstetric practice. It was pointed out by Levret that it was a frequent cause of laborious labor and of post-partum haemorrhage. The attachment of the pla- centa to the lower segment of the uterus so modifies its thick- ness, vascularity, and capacity for contracting equally with the other portions of the uterus situated in the same zone, that the labor is rendered painful, and lingering; and, when the child is born, the faulty position of the uterus, added to previous ex- haustion, disposes to a renewal of haemorrhage. There is another fact of practical interest. The frequent com- plication of cross-presentation of the child with placenta prae- via has often been observed. The explanation of Levret satis- factorily ranges the two facts in the relation of cause and effect. In describing a case where the head was thrown on one side, which he delivered by the forceps, he says: "II n'est pas difficile de decider que le placenta s'ctant fortuitement attache" du cote droit pres de I'orifice ; il a du empecher la matrice de se dilater suffisamment de ce cote, consequemment il l'a oblige a. prendre une figure oblique. Mais ce qui a totalement deter- mine" cette mauvaise situation a ete l'inflexibilite" de I'orifice de cet organe en cet endroit, lequel j'ai reconnu dur et comme cal- leux, pendant que son cote oppose etait totalement efface. II fallait done, par ces raisons, que I'enfant, se presentant par la tete, elle s'engageat dans ce detroit suivant une ligne oblique a la rectitude du corps." And at page 125 : " La clifficulte de l'enfantement ne vient pas seulement dei'obliquite de la matrice, mais encore de la difficulte que I'orifice a a se dilater dans le lieu prochain de Pattache du placenta, par la raison que la paroi de ce viscere est plus epaisse dans cet endroit." The following diagram will serve to impress this fact. I believe these considerations present a rational explanation of a multitude of cases of prae-partum haemorrhage, lingering labor, cross-births, and post-partum haemorrhage, the cause of which has been altogether overlooked. Having considered the varieties of seat of the placenta we are naturally led to examine the relation of the several parts of RELATIVE SIZE OF MUSCULAR FD3RES. 449 the muscular structure of the uterus to the placenta in its differ- ent positions. The general disposition of the muscular fibres of A, The rigid inclined plane formed by the placenta, and hypertrophied placental seat of uterus, throwing foetal head over to B, The thin yielding portion of uterus. C Thin yielding portion of uterus distended by hydrostatic pressure. the uterus may be taken to be pretty accurately determined. There is a general accordance amongst anatomists concerning the leading points. The dissections of the Hunters confirmed, cor- recting somewhat, the description of Ruysch, and these in their turn have been confirmed by the dissections of Sir Charles Bell, Professor Owen, and others. Preparations may be seen in most museums which exhibit clearly the disposition of the muscular fibres in the different regions. I must, however, recite to you the description of Sir Charles Bell, not only on account of its graphic beauty, but also because he has laid the anatomical foundation of those physiological views concerning praevial pla- centa to which I was led by clinical observation. " It has been proved by the sections of the uterus made in 29 450 ACTION OF THE UTERUS WITH PLACENTA PREVIA. different states of its contraction, that the order of the muscular fibres is calculated so as to close the vessels ; that where Nature has provided for the attachment of the placenta, there the bro- ken vessels are guarded by th,e provision of the surrounding mus- cular texture; but we know also that during this contraction of the superior part of the womb, the lower part dilates and relaxes. Now if the contraction of the womb be essential to the safety of the mother, what will be the effect of the attachment of the placenta to a part of the womb which must relax during the labor! Every one knows the peculiar danger of placenta pre- via, that each labor-pain as it returns increases the violence of the flooding- instead of checking; it. " I have been led to conclude that the placenta cannot be par- tially separated if it be attached in a regular circle to the fun- J dus of the uterus: it cannot be partially separated, and cannot be separated bodily until the uterus is permitted to have a great degree of contraction by the delivery of the child ; the circular muscles of the fundus being agents in a double capacity, that is, both in expelling the child, and in constringing the uterine ves- sels, byr the time the child is expelled, the vessels of the fundus are greatly diminished in diameter. Further, the place and strength of the muscles being perfectly regular and uniform, their action must have the effect of equally drawing the surface of the uterus, which is in correspondence with the margin of the placenta; but no one part of it will be separated until the general restriction is nearly completed. This will not be the case when the margin of the placenta extends irregularly, or when the placenta is attached to the side of the uterus. After the delivery of the child in cases 0/ flooding, it is not uncom- mon to find a portion of the placenta low down in the uterus, and separated, while the greater portion remains attached to the fundus. In examining the inner surface of the uterus by dis- section, I have seen the part corresponding with the placenta irregular in its form and extending towards the side and neck of v the uterus. In such circumstances of the attachment of the placenta, the retraction on the lower part of the womb being to a greater extent than the fundus, will account for the too early separation of that margin of the placenta which stretches towards the orifice and also for the haemorrhage which is a con- sequence of this partial separation ; but, in progress of the labor ZONES OF PLACENTAL ATTACHMENT. 451 and after the discharge of the waters, the more powerful efforts of the uterus draw the muscular fibres more closely around the bloodvessels, and then the flooding ceases." The chief points in the physiology of placental attachment are expressed in the following diagram : *fUNDALZONE* SAFE '///^CENTAL SE^T \ ^££jft POLAR circle!, 1 MERIDIONAL ZONE I S4/r£ PLACENTAL SEtf 1 TEDIOUS LABOUR fl t°ST-PARTm FLOODlW ^ERVICALZOW DANGER^^LACE^^SEM Diagram illustrating the various sites of the placenta, and the relation of these sites to h^mor- rhage. The inner surface of the womb may be divided into three zones or regions by two latitudinal circles. The upper circle may be called the Upper Polar Circle. Above it is the fundus of the uterus. This is the seat of fundal placenta: the most natural position. It is the zone or region of Safe Attachment. The lower circle is the Lower Polar Circle. It divides the cer- vical zone or region from the meridional zone. The space com- prised between the two circles is the region of lateral placenta. When attached in this region, the placenta is not liable to pre- vious detachment. It may, however, cause obliquity of tne uterus, transverse position of the child, lingering labor, ana dispose to retention of the placenta and post-partum haemor- Below this circle is the cervical zone : the region of danger- ous placental attachment. All placenta fixed here, whether it 452 EXACT POSITION OF LOWER CIRCLE. consist in a flap encroaching downwards from the meridional zone, or whether it be the entire placenta, is liable to previous detachment. The mouth of the womb must be pulled open to give passage to the head. This enormous contraction or retrac- tion of the longitudinal cervical fibres is incompatible with the preservation of the adhesion of the placenta which is within its scope. In every other part of the womb, there is an easy rela- tion between the contractile limits of the muscular structure and that of the cohering placenta. Within the cervical region this relation is lost. The contraction of the uterine tissue is in excess. The lower Polar Circle is, then, the physiological line of demar- cation between praevial and lateral placenta: it is the boundary- line below which you have spontaneous placental detachment and haemorrhage ; above which, spontaneous placental detach- ment and haemorrhage cease. If, through the successive active contractions of the longitudinal muscle, all that part of the pla- centa which had been originally adherent within the cervical zone, be detached; and if, as is the constant tendency of Nature, these intermitting active contractions, and the continuous tonic contraction going on in the intervals, arrest the haemorrhage, a stage is reached when the labor is free from all praevial placental complication ; the cervical placenta has become changed into a lateral placenta ; the labor is, in all respects, a natural labor. It is important to determine the exact position of this lower Polar Circle or boundary-line between haemorrhage and safety. The means exist of defining this with tolerable accuracy. In the first place, if we reflect that the lower segment of the womb must open to an extent corresponding to the circumfer- ence of the child's head in order to permit its extrusion, we shall, by noting the amount of necessary recession or shortening of the neck of the womb, in order to reach this extent of expan- sion, obtain a measure of the original depth of the ceryical zone, the region of praevial placental attachment. The following dia- gram will serve to illustrate this position : There is another evidence distinct from, but confirmino- the preceding. If, after its expulsion, we examine a placenta, the edge of which, at the beginning of labor at the full term had been felt reaching to the edge of the os uteri internum, we find that part which had been adherent within the cervical zone and BOUNDARY LINE OF SAFETY. 453 which had been consequently detached, infiltrated with coagu- lated blood, its substance perhaps indurated, and altogether pre- senting an appearance quite different from that of the mass of the organ which had adhered within the meridional zone, and Diagram showing a lateral placenta descending to (AA) the boundary line between the meridional and cervical zones. In this case the placenta descends to the very point of fullest expansion of the os, and therefore remains just within the limit of safe attachment. The space between AA and BB is the necessary range of orificial expansion. which had only become detached after the expulsion of the child, through the general contraction of the womb. This part is usually so well defined as to admit of being measured. It is usually found to vary from three to four inches in length. This distance from the os will bring us again to the lower Polar Cir- cle. I believe, however, that the boundary-line of safety is often practically reached before the expansion of the mouth of the womb has reached the full diameter of the child's head. I have observed that the haemorrhage has completely stopped when the 454 TREATMENT OF VARIETIES OF PLACENTA PREVIA. os uteri had opened to the size of the rim of a wine-glass, or even to a lesser size. In ordinary labor, when the bag of mem- branes or the child's head is driven down upon the os by the pressure from behind—that is, when expulsive pains succeed to the preliminary dilating pains, the presenting part becomes a mechanical distending or stretching power. The os, partly opened by the active shortening of the longitudinal muscular fibres, is fully opened by the distending cone driven through it, as an india-rubber band is expanded. Thus it is that a part of the opening of the os uteri is gained by a process that does not involve detachment of placenta. These cases and arguments demonstratively exclude the operation of artificial total detachment of the placenta as a, prin- ciple of treatment of placenta praevia. These cases in reality furnish strong presumptive evidence to corroborate the positive evidence I have adduced, that partial detachment of the placen- ta—i. e., detachment of the portion implanted within the cervi- cal zone of the uterus, may be enough—certain favorable con- ditions concurring—to control the haemorrhage. Now this partial detachment is an operation that admits of being accomplished by the introduction of one or two fingers, and is therefore feasible under the precise circumstances which preclude turning or total detachment. We have, then, here a new remedy, one applicable at the very juncture where ordinary means are impossible or danger- ous. As contrasted with the operation of totally detaching the placenta, it has the further advantage of not endangering the life of the child. As contrasted with forced delivery, it has also the advantage of being less hazardous to the child. The operation which I propose is, to carry the detachment further, so as to separate all that part of the placenta which ad- heres within the cervical zone or region of dangerous placental seat. It remains to endeavor to generalize trie varieties of cases of placenta praevia; and to endeavor to define the methods of treatment more particularly applicable to each variety. 1. We have those terrible cases to which we have just ad- verted, where the os uteri is rigid and undilated, the flooding profuse, the powers of life ebbing fast; where to wait for spon- ERGOT AND GALVANISM IN PLACENTA PREVIA. 455 taneous arrest of flooding, or the natural dilatation of the os, is to wait for death. These are preeminently the cases for resort to the operation referred to. It must, however, be first stated, that this class admits of being further subdivided. There are cases in which contraction of the uterus is going on ; there are cases—more dangerous still—in which contraction is absent. Labor with relaxation is dangerous under almost every con- dition : it is eminently so when complicated with placenta praevia. Where contraction is present, we possess one necessary ele- ment of safety; we may be satisfied with the artificial separa- tion of the placenta from its attachment to the cervical zone. Where contraction is absent, we must at the same time use every available means of rousing the contractile energy of the womb. Sometimes the stimulus imparted to the reflex system by the necessary manipulation is itself enough to excite con- traction. But not always. We must then give stimulants in- ternally ; apply warmth to the surface if the skin is cold and there is great depression; rub the abdominal muscles and the body of the uterus firmly. This is a case where the ergot of rye is especially indicated. If it fail, then we have galvanism, which rarely or never fails—an agent perfectly under control, which we can apply and intermit at pleasure, and whose force we can graduate as we like. If the haemorrhage should continue, or be renewed with urgency, I propose as the next step, tlie total cervical de- tachment of the placenta. The detachment must be carried further, by sweeping the finger round between the placenta and uterus on that side to which the main bulk of the organ adheres. In this manner the whole of that part which had been seated within the cervical zone will have been detached. We shall have imitated the operation represented in the diagram fig. 124, as being occasionally—I believe often—effected by the spon- taneous efforts of Nature. Now this detachment will not of itself stop the haemorrhage. We may, I think, ^anquillize our minds as to the effect on th^ mother of that small portion that will escape from the detached placental surface. But the uter- ine vessels may pour forth blood until'the haemostatic resources of Nature or Art come in to play. Those I have before des- cribed : continued contraction of the muscular structure of the 456 TOTAL CERVICAL DETACHMENT OF PLACENTA. womb, the contractile action of the coats of the uterine arteries, and the formation of coagula in their mouths. In the major- ity of cases, these resources are sufficient; the haemostatic pro- cess may, however, be further assisted by plugging again. A method of plugging is recommended by high authority, which appears deserving of attention. Moreau advises the application of a lemon, the end of which has been cut off, to the os uteri, and to retain this in situ by firm pressure through rags or sponge. The acid juice favors coagulation as well as the pres- sure, and retention of blood. The soaking of the sponges or rags used for plugging in vinegar is a common practice ; but it seems to me reasonable that more powerful styptics should be used. I suggested some time ago, the injection of the sesquichloride of iron. Dr. Schreier, of Hamburg, has related some instances in which this agent was employed with success. M. Dupierris, of Havana, advises the use of tincture of iodine. He says that he has injected a mixture of one-third tincture of iodine with two-thirds water, in one hundred cases of uterine haemorrhage of various kinds with uniform success. He relates three cases of haemorrhage attending labor. The sesquichloride of iron, how- ever, appears to me the preferable agent. By the proceedings I have described, . we may reasonably hope that in the vast majority of cases the haemorrhage will cease. If it should not, time will have been gained; the os uteri may have become soft and dilated; and, in the event of its being felt necessary to resort to forced delivery, this opera- tion may be performed with comparative ease and safety. 2. There is another class of cases, happily more frequent than the preceding, where there is less urgency, more scope for tem- porizing. We have seen that the expansion of the os may.be effected without necessary loss of blood to such an extent as to constitute flooding. In the conduct of such cases we have, in the physiology which I have enunciated, a guiding principle that carries a rational faith in the resources of Nature. It is in these cases that the natural tendency to restrain the flooding caused by the successive detachments of zonular portions of placenta is most strikingly marked. A knowledge of this prin- ciple will give an intelligent confidence in all those measures, such as the plug, ergot, rupturing the membranes, which has been recommended on various physiological or empirical STYPTICS IN PLACENTA PREVIA. 457 grounds. Even in these cases the operation of freeing the smaller segment of the placenta, so as to allow it to be carried over to the side of the uterus which holds the main body, will be of essential service. 3. There is a third class of cases in which the principle is all- important. I mean those cases where, after even alarming loss- es, the haemorrhage has ceased spontaneously. Under the prevailing dogmas the arrest of haemorrhage inspires no hope in the breast of the accoucheur. He is taught to believe that it will " unavoidably" return ; he hastens to deliver; and the poor woman who had reached the haven of safety is destroyed by the operation, a victim of the " nimia diligentia medici."] LECTURE XXX. FUNIS PRESENTATIONS. Gentlemen :—The Funis may present alone at the beginning of labor, or it may descend with the head, arm, nates, and any other presentation of the foetus. Its positive frequency is greatest in head cases, but relatively it is more frequent in arm and shoulder presentations than in other varieties. This serious complication may occur at any time during labor. It may happen before the evacuation of the liquor amnii, when the head or presenting part is passing the os uteri, or when it is emerging from the perinaeum. The Causes of funis presentations are various. In arm cases, where the body of the child lies transversely, the anatom- ical position of the umbilicus and the funis favors the descent of the cord, and this descent is still further promoted by the fact, that in shoulder cases the circular os uteri does not at all points closely embrace the presenting part, on account of its irregu- larities. In its contractions, the uterus cannot sweep equably over the shoulder as it does in cranial presentations during the pains, so as to carry up the funis when there is any tendency to prolapse. Presentations of the feet and breech, or of the hands and feet, are frequently complicated with the funis, and from the same causes. In the case of head presentations, length of the cord, small size of the head, the descent of the hand with the head, a large quantity of liquor amnii, and its sudden evac- uation, or a pelvis above the average size, may cause prolapsus of the cord. It happens in twin cases, particularly in the de- livery of the second child. The position of the placenta is also influential as a cause of funis presentations. The cord is prone to descend when the placenta is partially attached to the os uteri, or when the placenta is fixed to the lateral walls of the placenta instead of to the fundus, or when the placenta being STATISTICS OF PRESENTATION OF THE FUNIS. 459 seated near the fundus, the cord is inserted into the edge instead of the centre of its diameter. Mr. Roberton, of Manchester, points out that, in cases of contraction of the brim of the pelvis, where, on the rupture of the membranes, the head does not de- scend upon the os uteri, but remains suspended at the brim, the funis is very apt to float down with the liquor amnii and pass through the os. An interesting series of cases has been reported by Mr. Roberton, which fully bears out this view. When the head of the foetus remains above the os uteri, the relations of the os to the presentation very much resemble those which ob- tain in shoulder or nates cases. There is a want of that apposi- tion between the os uteri and the presenting part which prevents prolapsus of the cord in perfectly natural cases. As regards the frequency of this complication, Dr. Fleetwood Churchill has collected 128,224 cases of all presentations, which yielded 579 funis cases, or about 1 in 221*. As regards the mother, labor is not in the least degree rendered more unfavor- FlG. 125. Presentation of the Funis, with the head in the first position. able than usual, but the mortality to the foetus is very great. Considerably more than 1 in 2 of the children die in cases where the cord presents. In arm presentations the mortality is rather 460 FUNIS PRESENTATION SIMULATED. more than 1 in 2. It will be remembered that in breech cases the mortality was 1 in 34-, and in footling cases, 1 in 24. In turning, the foetal mortality is rather more than 1 in 3. Thus the preseutaXioix-of the funis is more dangerous to the child than any other variety of labor. The symptoms of funis presentations are sufficiently Fig. 126. Presentation of the funis, with a hand and foot. well marked to make their diagnosis easy. Sometimes a loop of cord, several inches in length, hangs from the vagina. It may be pulsating, or it may be cold and flaccid. But in one case the umbilical pulse, and in the other the twisted arrange- ment of the cord, or an ocular inspection, will remove all doubt. In cases where the cord comes down with the advancing part of the child, or presents with it at the os uteri, the only part of the full-grown foetus which can be mistaken for it is the closed hand or the toes. The knuckles, when only part of the hand is felt, or the row of toes, may feel somewhat like the end of a loop of cord. But the presence or absence of pulsation, and the exam- ination of a few inches of the cord, or enough of the extremities to reach the wrist or the ankle, will make the matter clear. There is one complication of labor which it is necessary to men- tion, in which a mistake respecting the cord may lead to the most serious results. In cases of ruptured uterus, a coil of the FUNIS VERSUS BREECH AND FOOTLING CASES. 461 small intestine may pass through the laceration, and present in the os uteri or the passage. This has, in rare instances, been mistaken for the cord of a dead child, and pulled down or even cut off by ignorant or incautious persons. A case of this kind occurred in London, and another in Ireland, incredible as it may appear, within the last ten or twelve years. In cases of this kind happening to a midwife, in which a medical man might be called after the rupture of the uterus and prolapse of the in- testine, some little caution would be necessary to avoid mischief. An inexperienced accoucheur might pull at the supposed cord, and do the gravest injury, particularly if the previous history of the case had been kept from him. Of course, the cause of the Mortality in funis cases is the pressure exerted upon the cord, between the presenting parts of the child and the hard and soft parts of the mother. The child dies of asphyxia, the fcetal circulation being, in severe cases, en- tirely cut off from the respiratory functions of the placenta. We may compare the child under the circumstances of funis presen- tation, to cases of turning, to cases in which the placenta is separated, or the contractions of the uterus are so intense and continuous as to prevent the circulation of the blood in the maternal side of the placenta. The comparison between the presentation of the funis, and the descent of the nates or feet foremost, is very obvious. Wherever the order of labor is such that the funis, or any portion of it, precedes the descent of the more bulky portions of the foetus, the case is essentially one of funis presentation. Thus, in footling, breech, and turning cases, as soon as the umbilicus engages in the pelvis, pressure is ex- erted on the cord, and the cases are identical with funis presen- tation. The mortality depends on the length of time to which the funis is subject to pressure, and the degree of the pressure during the exit of the foetus. Thus it is greatest in funis cases proper, in which the cord comes before or with the presenting part, and is thus subjected to pressure during the whole of labor. Next to this, footling cases are the most fatal to tlje child, as here the pressure on the cord commences as the umbi- licus descends through the soft parts, and these have been but little distended by the descent of the feet and breech in succes- sion. In breech cases, the mortality is less than in footling cases, because the soft parts have been distended by the passage of the 462 DANGERS OF FUNIS PRESENTATIONS. nates with the feet doubled up towards the abdomen. In cases of the descent of the cord with the head, in cranial or face pre- sentations, the pressure exerted on the cord is greater than under any other circumstances ; but it is of short duration, since as soon as air can reach the mouth of the foetus, pressure on the cord becomes of little consequence. No comparison can be made between the mortality in cases of turning and funis pre- sentations, because the great mortality to the foetus in turning depends on other causes as well as upon the pressure upon the cord. Certain circumstances besides the presentation exert an influence upon the mortality in funis cases. The younger the foetus, for instance, the more safely pressure is borne, and the longer it may be continued without a fatal result. The risks of a fatal result to the child, when the funis presents in a first labor, are very great, whatever the part presenting with the cord. They are much less in the case of patients who have had many and easy labors. The danger is greater when the foetus is male than female. The least dangerous cases of cord presenta- tion are those in which it happens to the second child in twin cases, especially when, as is frequently the case, the second child is smaller than the first. The danger is increased when the pains are very frequent and prolonged, but when the pains are moderate, and with a fair interval, the child recovers from the effects of the pressure of one pain before another comes on. Care should always be taken to inform the friends of the patient of the danger in which the child is placed by the descent of the funis. The principle of Treatment in funis presentation is the removal of the cord from pressure, or subjecting it to compres- sion for as short a time as possible. These objects may be car- ried out by the Reposition of the Cord within the uterus; by placing it in such a situation in the pelvis as to escape pressure as far as is practicable; or by artificial delivery, as by turning, or the use of the forceps. No one method can be advised for fye treatment of such cases. The principle of management being held in view, the means adopted in individual cases must depend upon the exigencies which attend them. As the mother is not in danger from this casualty, no steps should be taken to secure the child which are likely to bring the mother into danger, as this would be substituting a greater for a lesser evil. VARIOUS METHODS OF REPOSING THE CORD. 463 A primary rule in the management of these cases is, the pre- servation of the liquor amnii. As long as the membranes remain unbroken, it is hardly possible for the child to be destroyed bj compression of the cord, and not until they are broken should any attempt be made to replace the funis. It cannot be done effectually ; the child is as yet in little or no danger; and attempts at manipulation must hazard the rupture of the membranes. The more labor progresses before the evac- uation of the amnion, the shorter will be the time of serious compression, and the less the amount of compression will be from the gradual dilatation of the soft parts under fluid pres- sure. The Reposition of the cord within the uterus is the most satisfactory method of treatment we can adopt, but un- fortunately it is not always practicable, or else the pains cause the renewed descent of the cord after its temporary replace- ment. The degree to which the cord should be returned is a matter of some difference of opinion. Sir Richard Croft recommended that the cord should be carried up into the uterus so as to hang it upon the limbs of the child. Others, as Arneth of Vienna, advise that it should be returned above the head, and allowed to remain in the hollow formed by the neck. No doubt, the latter answers every purpose, if the cord will keep there, since children are frequently born with the cord coiled once or twice round the neck without injury, and the introduc- tion of the hand into the uterus during labor is necessarily attended with some risk to the mother, except in the most favorable cases. Various methods of procedure have been advised for the reposition of the cord. The most simple instru- mental method is by the use of a whalebone needle, or bodkin, and a loop of tape. This, as Dr. Ramsbotham remarks, has the advantage of being made extemporaneously in a few minutes in the lying-in room. A flat piece of moderately flexible whale- bone, about half an inch in breadth and a foot in length, and a yard of tape, are all that is necessary for its construction. An eye or hole should be made near one extremity of the whale- bone, large enough to allow the tape to run in it readily. In using it, a loop of the tape should be passed through the eye, and the end of the loop of funis should be included in the loop of the tape, when the ends of the tape should be drawn so as to 464 INSTRUMENTS FOR REPOSING THE CORD. bring the loop of funis towards the eye of the instrument, and to retain it there without exerting pressure enough on the cord to interfere with the placenta-foetal circulation. The whalebone should now be passed into the uterus by the side of the present- ing part, in an interval between the pains, and after having been kept there during a pain, the tape may be brought away by drawing at one of the strings, and the slip of whalebone after- wards removed. If this noose be relaxed a little, so as to avoid strangulation of the cord, there can be no harm in leaving the instrument in the utero-vaginal canal, as it offers no impediment to the progress of labor. Michaelis, of Kiel, recommended that a large sized, male, gum-elastic, stiletted catheter should be used for the same purpose. He advised that the ligature should be passed through the loop of funis, when, being drawn loosely to the eye of the catheter, and the stilette being introduced only so as to avoid the possibility of doing injury, the instrument is to be passed above the head or presenting part, and left there, the stilette being withdrawn, until the completion of labor. But at the present time, Michaelis has, I believe, abandoned his ingenious instrument for the use of the fingers. [A very ingenious instrument called a portecordon is made by Luer from whalebone or hard rubber, as shown in the annexed cut. It is made in two portions, one sliding over the other. In g= a--- qgja^ a sharp bend at one extremity the cord is seized and may then be pushed up to the fundus uteri if desired when the passage is not blocked. Then, by withdrawing the slide, the cord may be disengaged and the instrument withdrawn; or, if desired, the instrument may remain, its smallness preventing its causing any obstruction or being in the way, while its retention may more effectually prevent the subsequent descent of the cord.] I see no reason why the cord should not, when it is suffi- ciently low to admit of manipulation, and when it returns after reposition, be pierced with a needle and thread or worsted, in NO DESPAIR WHILE THE CORD PULSATES. 465 such a way as to escape the vessels, and be tied to the end of a slip of whalebone, which might then be returned, and kept in situ until the completion of labor. But in ordinary cases, the accoucheur can do more with the hand and fingers than with the most ingenious instruments. In returning the cord with the hand, two or three fingers of the right or left hand, as may be most convenient, should be introduced by the side of the head or pre- senting part, and with the tips of the fingers the prolapsed por- tion of the cord, being gathered together, should be pressed up- wards, during an interval of freedom from pain, and retained above the presenting part until the next pain comes on. When the uterine contraction of the uterus reaches the fingers, they should be withdrawn, so as, if possible, to leave the funis within the grasp of the uterus. The contraction of the uterus will, if the operation be successful, sweep the cord upwards, instead of expelling it. It may, however, come down again when the uterus is relaxed, or it may be extruded by the succeeding pains, and require other attempts of the same kind to keep it above the presenting part. Drs. M'Clintock and Hardy, whose direc- tions for the reposition of the cord are very excellent, advise that in attempting its reduction by the hand, the woman should lie upon the side opposite to that on which the cord protrudes; that is, if the cord be felt on the right side of the pelvis, the woman should lie on her left side, and vice versa. They also recommend that before its return it should be drawn, if possible, towards the pubes, as the shallowness of the pelvis in this situa- tion renders the return of the procident cord more easy than when it lies towards the sacrum. As long as the pulsation of the cord is vigorous, we should not be deterred by difficulties in attempting its reposition, as this is sometimes effected only after repeated trials. When, in spite of our endeavors, the cord slips down again at every pain, means are recommended for keeping the funis above the presenting part. This may sometimes be done by passing a wedge of sponge up after the cord, as recommended by Dr. Collins, so that when the pains come on, the sponge is com- pressed between the presentation and the walls of the canal, and the further descent of the funis prevented. Sometimes, where the extent of funis prolapsed is considerable, and the cord thin, so as easily to slip down, some authorities have recommended 30 466 OPERATIONS IN CORD PRESENTATIONS. that it should be gathered together, and put in a soft leather pouch or bag, the mouth of which should be drawn together sufficiently to keep the mass in the bag, but not to constrict the » -Cord-.- The -bag is then to be passed up within the os uteri by the fingers. This manoeuvre substitutes a considerable mass for the thin lubricious cord, and is less likely to be protruded after its reposition. The bag remains, when the proceeding is suc- cessful, until the child is expelled. This operation is, however, difficult, and one now rarely, if ever, attempted. When the cord cannot be returned or retained within the uterus, it becomes necessary to place the prolapsed cord in such a position in the pelvis that it may be compressed as little as possible during the passage of the child. It should be brought, as recommended by Dr. S. Merriman, into the oblique diameter of the pelvis, opposite to that which is occupied by the child. In a vertex case in the first position, with the head in the right oblique diameter, the funis should be kept as closely as possible to the left sacro-iliac synchondrosis, in the second position, with the head in the left oblique diameter, and in both cases the rec- tum should be emptied, but particularly in the first, as the cord then lies between the side of the child's head and the rectum of the mother. In other presentations, when no other assistance can be rendered or seems necessary, the cord should be shifted as far as possible into that part of the pelvis which is least occu- pied by the child. It should rarely, if ever, be brought towards the pubic arch, as in this position the effects of pressure are generally very great. In cases of large pelvis in multiparous women, when the pains are moderately strong, and occurring at proper intervals, the passages being well relaxed, and labor com- pleted in a short time, the arrangement of the position of the cord will often be sufficient to secure the safety of the foetus. In primiparous women, or where there is rigidity of the soft parts and a small pelvis, such measures are of little or no avail in arresting the long effects of pressure. The propriety of Turning in cases of funis presentation, combined with any other part of the child than its pelvic extrem- ity, is one of the vexed questions of obstetrics. Many eminent authorities have commended, and others condemned, this prac- tice. The truth is, that the fitness of turning for any particular case requires great tact and judgment, and admits of no reduc- TURNING IN FUNIS PRESENTATIONS. 467 tion to rule. Mauriceau performed it in a number of cases with great success in saving the child. So did Boivin and Lachapelle, and so have many contemporary accoucheurs. The strong point in the operation is, that it enables us to complete delivery in a shorter time than would otherwise be the case, and in this way the chances of safety to the child are increased. The weak points are, that the operation is not perfect, considered in relation to the object we have in view. It does not deliver the child from danger, but substitutes the risk of pressure from the shoulders and head upon the cord after the passages have been distended by the breech, for the primary pressure of the cord by the head without any previous distension of the parturient canal. Of course, in arm cases in which the funis presents, version is performed, but with reference rather to the arm than the funis complication. It would be very interesting to have a statistical comparison between the results to the child in those cases in which the funis presents in combination with the pelvic extremity and those in which it presents with the cephalic end of the foetus. But I believe no such statistics exist, and, in their absence, we must consider the question of turning upon other grounds. In this country, the tendency, in recent /ears, has been to consider, with Dr. Robert Lee, that turning should rarely be practised. I believe the cases in which version is in proper operation, simply on account of funis presentation, are rare; but there are other contingencies, such as moderate contraction of the pelvis, cases where the pelvis is capacious, where other means have been tried in vain, and where turning can be easily performed, but there is evidence that the child is passing into a dangerous state, in which the operation of turning will save fcetal life without more than very slight hazard to the mother. In cases where the labor has sufficiently advanced, the use of the forceps or the vectis, the administration of the ergot of rye or a stimulating enema, are of great value in completing delivery. These means are to be reserved for those cases in which prolapsus occurs, or continues, when the head is low in the pelvis, and the os uteri is fully dilated. In cases where the funis is complicated with breech or footling presentation, the means described when speaking of breech cases, for hastening delivery and preserving the child, should be practised. When the cord remains pulseless and flaccid for a considera- 468 POSTURAL TREATMENT IN FUNIS PRESENTATIONS. ble time, the child is already dead, and we may save ourselves from anxiety or attempts at delivery. We must not, however, be in too great a hurry to consider the child beyond hope. Cases are on record in which the cord being pressed upon from above, the loop hanging down is pulseless from pressure on the arteries, but the heart may beat for a considerable time, and the child ultimately be born alive. Sometimes in the conduct of these cases, the cord will cease to pulsate and the heart of the child will fail, but nevertheless, from some alteration of posi- tion, the heart rallies and the pulsation of the cord is restored. Those cases in which the cord comes down with the head, most easily admit of the reposition of the cord, where, as in breech cases, the cord has a great tendency to come down after its re- placement. Although when the cord comes down before the rup- ture of the liquor amnii, the child is in no danger as long as the membranes remain intact, such cases are very dangerous to the child from the length of time during which it is generally sub- j ected to pressure. On the contrary, when the cord descends towards the completion of labor, the risks of the child are less, because vje generally have it in our power to complete delivery within a given time in such cases. The length of time the cord may prolapse in some cases without destroying the child, is ex- traordinary. I once knew a case where it was prolapsed three whole days, but was afterwards reposited, and the child was born alive. [In a recent paper read by Dr. T. Gaillard Thomas, to the N. Y. Academy of Medicine, a new and very ingenious method was proposed, which he calls postural treatment, by which to re- turn the cord into the cavity of the abdomen. The causes of prolapsus of the funis he enumerated are, 1st, the slippery na- ture of the cord itself, and 2d, the inclined direction of the uter- ine axis, which being a line running from the umbilicus, or a lit- tle above it, to the coccyx, favors very much the tendency of the slippery part to roll outwards. These conditions can be overcome, and also are themselves rendered serviceable in effecting reduction, by inverting the uterine axis, to be effected by placing the woman upon her hands and knees. Dr. Thomas's rules of treatment are thus given by him— 1st. If the cord is detected before the waters have broken RULES OF POSTURAL TREATMENT. 469 let no manual assistance be offered, but place the woman at once in position and trust to this for its return to the uterus. 2d. Should the waters have flowed away, and left the cord 470 thomas's postural treatment. below the head, place the woman in position, and push it up with the hand if practicable, or with a portecordon, if not so. —3d. Lei n