-- V ' '■'^■r'^'-'J'"". J.! U>,1'^.'','/«'>'*■,',>.'■.■' .f ' ■;""■',• '.'•'■ ■-■' '•'• , ■././';, NLM 0D13T131 fi t^a^iJit NLM001391318 I PROGRESSIVE MEDICINE. A SCIENTIFIC AND PRACTICAL TREATISE ON DISEASES OF THE DIGESTIVE ORGANS AND THE COMPLICATIONS ARISING, THEREFROM. CIKO DE StZZARA-VERDI, M. D., LATE Acting Assist ant-Surgeon at Balfour Hospital, U. S. A., Professor of Physiology and Pathology in the Cleveland Homeopathic College for Women. "iG 1^ " SlMILIA SlMILIBUS CURANTUR*" When the art of preserving life is in question, neglecting to learn is a crime.—Hahnemann. PHILADELPHIA: F. E. BOERICKE. 1885. WI v 4 2 4- p X Entered, according to Act of Congress, in the year 1880, By CIRO DE SUZZARA-VERDI, M. D., In the office of the Librarian of Congress, at Washington, D. C. TO JOHN F. GRAY, M.D., IN TESTIMONY OF HIS ABILITY AS A LEARNED PHYSICIAN, AND HIS DEVOTION TO UNALLOYED TRUTH; AND ALSO AS AN ATTESTATION OF THE COURAGE WITH WHICH HE HAS DEFENDED LIBERAL MEDICAL PRACTICE, THIS WORK IS RESPECTFULLY DEDICATED, BY THE AUTHOR. New Brunswick, N. J., Jan. 1st., 1879. PREFACE. I have labored with the most earnest purpose to gather together all evidences, practical and scientific, chemico- physiological, medical and dynamical, in order to demonstrate the rationality of the law of similarity. Second.—I intend to bring forward some clinical cases, taken from my memorandum-book, as proofs of the success of progressive medicine. Third.—I have adopted a systematic course of pathology and physiology as the true and only basis on which a correct and reliable diagnosis can be formed ; at the same time veri- fying the specific curative action of medical agents upon the animal economy. In support of my axiom, I have examined and brought forward the opinion of eminent progressive scholars of medi- cine, viz.: Rasori, Voght, Magendie, Prout, Watson, Pareira, Graves, Huffland, Hoffman, and many others, who are repre- sentative members of the dominant—called by us Allopathic, which, however, they reject with indignation, preferring the name Regular, or Rational—school of medicine. We shall not quarrel on account of names, but on account of princi- ples and truth. Fourth.—Physiology is so necessary, and so intimately con- nected with medicine, that I had constantly to recur to it, even if seemingly tedious; for that is the basis on which we can treat diseases successfully with the system of homoe- opathy. Fifth.—I found chemistry and physical science also two great supports of my subject, as they bring forward continu- ally proofs in favor of our school of medicine, and sustain the basis of the law of Similia similibus curantur. 8 PREFACE. Sixth.—I endeavored (though I might displease some emi- nent extreme parties of both schools) to treat my subject upon clinical ground, sustained by rational deductions from science and from medical experience. It is needless to remark, that he who dares to differ and predicate new discoveries or new thoughts, must be ready to meet fearlessly the indignation and contempt of those who think that there is nothing beyond what they know and teach daily. There are surely men of both schools of medicine who are open to conviction and truth, and are ready to accept them and adopt them, even though contrary to former teaching and prejudices. To these true representatives of the medical profession I most respectfully look for an impartial verdict. [BY PERMISSION.] IMPORTANCE OF PHYSIOLOGICAL KNOWLEDGE. BY M. B. LUKENS, M. D. Cleveland, Ohio. It is one thing to obtain a knowledge of Physiology, and quite another to make the best practical use of it. New discoveries are continually flaunted before us. Theories are glibly explained. Yet everything seems to move on as usual. Some claim that the average duration of human life is gradually increasing. If this is true we can account for it in the diminished number of violent deaths—as in war—and in the smaller amount of poisons taken as medi- cines. Improvement in the treatment of disease alone is sufficient to favorably affect the average duration of life. This average at pres- ent is so far below the proper standard that a crusade should be organ- ized against existing practices, which are considered highly civilized, but which the physiologist knows to be detrimental to life. He who best understands machinery most readily detects the points where friction exists, and supplies the oil, knowing that by doing this he insures better work and increased durability. The human, the most complicated of machines, and infinitely the most valuable, ought to re- ceive at least equal attention and study. Perfection in mind and body should not be considered the wild dream PREFACE. 9 of some enthusiast, whose aim is to carry out some impossible theory, for our great prototype is perfection—man, made in the image of his Creator, to be reproduced in time, and the method of its reproduction should receive conscientious investigation. This aim may be ideal—one that can not be attained in this, or may be a score of generations; yet it is elevating and ennobling—physically, mentally, and morally—to raise the standard of thought and aspiration, and hence the standard of action. A knowledge of Physiology has this mission: It is to take its place among the influences, second to none, which are to elevate the moral condition of the world. It will not displace other good agencies, but will prove to be the strong backbone of all. Physiological knowledge, correctly directed, will diminish disease and lengthen life. Who is to enforce and direct this knowledge ? By whom are the people to be in- spired with a desire for instruction and learning, that their " days may be long in the land " ? Down deep in the souls of the masses will be found a willingness for instruction, and a seeking for the '' elixir of life." The parent would give worlds for some power to restore his dying child to life and health, little dreaming that the cause of his anguish lies within himself or his ante- cedents. For relief in all physical trouble the mind turns to the physician. The patient is satisfied with the removal of present suffering, and sel- dom inquires into its cause. There is entirely too much importance given to this individual dubbed "physician." No one ought to accept the guardianship of the health of the family or individual, unless he is a practical physiologist. If he is, he will look after the sanitary conditicns, and prevention will be ex- alted above cure. It might be safely said that all practical physiolo- gists are physicians; but all physicians are not practical physiologists. The present state of intelligence demands of the doctor removal of present pain ; so the supply is in accordance with the demand. Every one you meet has a cure for whatever disease afflicts you; and as far as they accomplish the object of removing pain they have as much moral right to recommend and use their remedies as hundreds who have ac- quired a legal right, by purchasing an "M. D." as an affix to their names; for all have the sane object in view, viz., to gratify the patient by removing or alleviating their pain temporarily. Few pretend to do more than this. Teachers ask no more from the graduate. In the be- ginning of his career he sounds his key-note—relief. He does not waste his energies in preventing disease; but when trouble overtakes his fel- low-man is willing and even anxious to assist him (for a moderate fee). He is generally honest, and does his work to the best of his ability, so as to gain a reputation as an expert in his-line, that he may be preferred above all competitors. It might be asked, "Is it not good to alleviate pain?" Most as- 10 PREFACE. suredly. It is also good to have appliances to extinguish fire after it is under headway ; but it is better to prevent the fire or make the build- ing fire-proof. What is the building worth after the fire is put out ? What is the body worth after a severe attack of disease ? From ten to twenty years of life are taken away by every severe illness. A wise physician has said, " To cure a disease is to prevent it." The conscien- tious physician will look to this, and endeavor to get above the practice of putting drugs into the stomach that he may the better put his hand into the pocket. When we study life, whether animal or vegetable, we find it made up of a succession of periods of growth and decay. From the deposit- ing of the germ there is a gradually ascending series to maturity, and from thence a descending one till death. Nature has, no doubt, affixed a limit to each epoch, the extent of which can never be exceeded and is seldom attained. In applying this law to human life it is impossible to ascertain the precise length of each epoch, or the aggregate whole of existence. The greatest age ever attained by man must fall short of the years he might have reached had he lived in strict conformity to the law of nature. The famous Thomas Parr, who lived one hundred and fifty-two years, was, no doubt, prematurely cut off in consequence of a change in his usual manner of living. It was found upon post-mortem examination that his cartilages had not turned to bone, as is the case with the very aged. All who die, whether early or late, have had the elements of a more enduring existence. The length of the descending series depends upon the length of the ascending series. The m Dre slowly maturity is reached, or the longer the first series, correspondingly longer will be the last series; or in the ratio of one of the former to four of the latter. Our calculation here will not admit of mathematical precision, but ap- proximates to the truth. The length of life depends upon the length of this period of youth. During this period the material is accumulated in the superstructure, which by constant accretion in after life determines the relative power of resistance. We know from experience, and draw our conclusions from nature, that the conditions of this period decide the state of after life. Health and longevity depend mainly upon the prolonging of the ascending series. Let physicians so deviate from their accustomed line of action as to give this feature especial attention. To promote healthy matur- ity will best promote longevity. The most of those who have carried bad habits and appetites beyond the period of maturity, remain unchanged during life; and, fortunately for the race, the life of many is short. Those who are diseased, physic- ally or morally, acquired the first taint of the malady during the ma- turing period, either before or after birth. All that skill can do for PREFACE. 11 them is to retard progress, and palliate their sufferings, for which ex- isting doctors have been especially educated. Drunkards, consumptives, nervous wrecks, and those with chronic taints, can find rest only in the grave. Some of the special means of promoting healthy growth are the food and the habits. From the beginning of life the proportion of the solid parts of the body is gaining upon the fluids. Natural death oc- curs when the structures become so consolidated that the fluid can not permeate the capillaries sufficiently to maintain the functions of nutri- tion and depuration. As the fluid and solid portions are formed mainly from the food and drink taken into the stomach, it follows that the character of the aliment has a controlling influence in determining when natural death shall take place. When an infant makes its appearance in the world it is a soft, pulpy, juicy thing, if the mother has been properly nourished during gestation. If she has indulged to a great degree in food rich in bone- producing elements, the child enters the world through much tribula- tion, with its bony parts advanced toward maturity far beyond the period of its existence. The fact seems to be well established, that the food which contains a large proportion of fluid as compared with its solid matter, and a large proportion of bulk as compared with nutriment, is best adapted to sustain permanently the organism, provided it contains the requisite elements of nutrition. All stock-growers know that animals raised for physical endurance should not be fed with concentrated food while maturing. Experience has shown that it is not the best practice, if they wish to produce a constitution capable of resisting hardship. So during the maturing period they are not allowed the same food as the matured animals which are subjected to hard work. But how different with the human young ! In the greater number of families, as soon as they are able to sit alone they are placed at the table and given the same food as the parents and grandparents. Such children, instead of having developed and fostered soft body tissue, have old people's tissue. They become old far beyond their years, both physically and mentally. They early develop a brilliancy which is very pleasing to the parents; and shortsighted and ignorant as most parents are, they yield readily to the delusion that they have the smartest children in the world, who are destined to make their mark. Such children usually do make their mark. There is a precocity of both mind and body which is unfortunate for its possessor and for so- ciety, for it makes the child a giant and the man a dwarf. It pro- duces manifestations of maturity at twelve, and symptoms of decay at twenty. If this forced production of a man propagate his kind, the offspring will inherit an imperfect organization. If we examine the main sources of education—the pulpit, schools, 12 PREFACE. and colleges,—we find no provision made for the symmetrical develop. ment of mind and body. If we analyze and grant all they claim for their respective spheres, we will still find that the physiologist stands alone to tight for the lives of the children. The central thought of the minister of the gospel is to induce the mind to reflect upon the Cre- ator; to remind the people that they have moral powers to improve. His specialty is the soul. Judging from his preaching, he knows nothing about the body—the dwelling-place of the soul. His business is not to save the dwelling, but to have the tenant " up and dressed," ready to depart when called for. He never tells how to keep the body in a sound and healthy condition. He never says anything about clothing, diet, dry feet, exercise, ventilation, etc. That is left for the doctors. But when the tenement is fallen and the tenant has departed, he pronounces encomiums over the wreck, and attributes this physical ruin to a wise and benevolent though inscrutable Providence, and cheers the living with the assertion that all is for the best. The pul ■ pit, then, fails to supply the need. We have been in the habit of looking upon the common schools and colleges of our country as par excellence for the education of the youth of the land. When we analyze their methods of work and see the effect upon the youth after passing through these educational mi'ls, we are forced to an adverse opinion. To preserve the body while the mind is being properly trained does not enter into the modern system of fashionable education. The art of keeping up the bone, muscle, and nerve of the pupil, so as to keep pace with the brain-development, is yet to be learned and practiced. The old Grecian and Roman idea of keeping the body strong and vigorous, whatever might be the state of the mind, is now considered a relic of barbarism, and no more to be brought into our civilized refined educational processes than are their modes of physical exercise, the Olympian games, gladiatorial contests, etc. The high-toned school of the cities and larger towns, whose machin- ery runs in such perfect order, is certainly "a thing of beauty," if not "a joy forever." If we look only to the perfect mental discipline, to the text-books mastered, to the grace and elegance acquired, such a school is certainly a model, but to the more practical observer, who looks forward to the stern realities of life, who appreciates good health, and believes that future usefulness depends as much upon a sound body as upon a cultivated mind, the schools appear to be conducted upon a false basis. Follow carefully a student through his whole course, and witness his graduation. It should be a source of great disappointment to both himself and his friends, that, after spending weeks, and perhaps months, in preparing an oration or an essay, he cannot be heard dis- tinctly a score of feet from the platform. I here place great stress upon this failm-e, for it is indicative of physical weakness. We rarely hear PREFACE. 13 the strong, sound, manly voice of the young man, which is a sure index of great physical endurance. We much more rarely hear the strong, rich, round, manly voice of the young woman, which points you to a body that is sound and healthy. When we contemplate the outgrowths of the modern and the most popular system of education, the truth is forced upon the mind that the plan is radically wrong. Education is not conducted as if the vigor, growth, and development of the mind depend upon the vigor, growth, and development of the body; but rather upon that old idea advanced by Dr. Watts—"the mind is the measure of the man." This sentiment is practically false, for it is the mind and the body which measures the man, the body standing first. It is better to be a healthy hod-carrier or laundress than a useless, broken-down graduate of some school. A graceful blending of the two extremes is a natural and healthy con- dition. What is education for, if not to make the whole being better ? —and is it not folly to adopt that system of culture as the one pre-emi- nently proper, which entirely neglects the one and gives undue attention to the other ? We should not demand less scholarly but greater bodily attainments. How far the young mind may be safely stimulated is yet an open question. No rule can be laid down for all cases. Early in life some minds show wonderful power, and take instant leadership among their fellows. These may be healthy, and to check them would be cruelly ruinous. The precocious must be held in mild restraint, and their inclinations be bent and unbent by the master hand of one who is wise in forecasting the future, and who is also able to encourage wisely the dull and stupid. That the mother may be this one, wise to form, govern, encourage, and restrain, the physician should assert his mission, to instruct her mind with physiological knowledge necessary for both the physical and mental development of her offspring. PROGRESSIVE MEDICINE. PAET I. CHAPTER I. MAL-ASSIMILATION, INANITION, AND DECAY. Science has established that the source and develop- ment of organic life, vegetable and animal, depends upon the co-ordination of three forces mainly, viz., phys- ical, chemical, and vital. This complex relation should be clearly defined in all its bearings, in order to mako our views comprehensible and acceptable. The subject is certainly of great importance to ph}rsi- cians, involving the great desideratum of life and its functions—disease and health. Firstly. What is vitality, and from whence does it arise ? These questions may be answered by saying that vital force arises from a process of decomposition and molec- ular disintegration; and this act is produced by atomic motion and molecular attraction. Those dynamic activ- ities form new compositions and new organizations of animal or vegetable matter. During this dynamical transition and separation of atoms, an attraction of mo- lecular particles is set up from an inherent static force, existing in an undeveloped condition within the matter itself, self-acting and with energy of its own. 16 PROGRESSIVE MEDICINE. Molecular force has a different origin from chemical force: it arises from a changing process of organized matter, which sets in motion the atoms that were in a state of cohesion. A molecular attraction takes place by affinity, and a new activity goes on and develops new forms; and therefore a new force springs up together with the energy of the molecular attraction and atomic motion. This is the vital force. As it increases with physical action, it also takes a superlative part in organ- izing matter into animal tissues. Can we suppose that this force is independent or pre- existing? I answer in the affirmative. If we admit a static force, we must then admit that this form and power exist in the organic matter, and it only needs the momentum or energy to bring it out; such as heat, moisture, motion, electricity, etc. This force appears with the birth of a new combination. From the commotion of atomic disintegration, motion and heat are two nat- ural results; and molecular attraction forms new com- pounds of organized matter. The process of decompo- sition, then, is unmistakably a physical law in order to form new compositions. It therefore changes the physical into chemical, the chemical into organic mat- ter, and the organic into a higher condition, or vital force. All these changes have a perfect unity of pro- gressive or retrogressive action. The first rising higher and higher, the latter (retrogression) descending to a lower condition, and through this process of molecular disintegration, new organizations, new formations, and a new life are reached. And rational reasoning demon- strates beyond question that action and re-action have a correlation of forces, so as to arrive at a perfect uni- formity of development. There is a vegetable vital force, and an animal vital force: the former continuous and unchanging, the latter constantly forming and de- caying. MAL-ASSIMILATION, INANITION, AND DECAY. 11 Vegetative life has only the function of growth; ani- mal life has growth, force, and repair. It is therefore conclusive that force is inherent in organic matter, wait- ing only the necessary energy. This energy may pro- ceed from various sources, viz., physical, chemical, and vital, in both vegetable and animal life; hence it is evi- dent that life springs from three forces—chemical, phys- ical, and vital. From physical commotion there are new organic compounds formed, i. e., oxidations, carbon- iferous, sulphurous, or volcanic emotions, and nitrogen- ous. These elementary forces go on forming new com- pounds called minerals, or alkaloid earths; and again, when these compounds become disintegrated, a chemi- cal force arises, and this atomic metamorphosis sets in motion a molecular affinity in favor of this or that ele- ment which may happen to predominate, i. e., oxygen, carbon, or nitrogen. Thus we perceive that new for- mations are constantly produced by atomic and molecu- lar activity. If we proceed a little further, under the influence of heat, light, and electricity, the mineral atomic cohesion of any substance must separate and come asunder; and from this physical activity new results take place, and a gas or a cell is formed. And once more, this cell is joined by affinity to other elementary substances; hence a nascent combination forms a pro- toplasma, a new birth, a new life, viz., a vital vegetable cell is formed. One step further: with a few more elements, i. e., sulphur, phosphorus, and nitrogen, from the same source or matter arises the vital animal cell. The vegetable substances are annualized by physiologi- cal process, and changed into animal matter and tissues. Through a combination of forces a proteine compound results, and the pabulum vitse is established. There- fore, vegetable matter must change by decomposition and disintegration, to give birth to a gas (nitrogen) rising from this process of fermentation. 18 PROGRESSIVE MEDICINE. The heat, the atomic motion, disintegration, molecular attraction and affinity, all combined, a vital force arises and new formations are developed, the final accomplish- ment of which is an animal cell. These preliminary steps will appear tedious, but without them I am afraid our subject would be indeed incomplete. I am sure that these few pages upon gen- eral laws will strengthen our mode of proceeding to physical and vital diseases. And just at this point of the subject we must acknowledge and adopt the great physiological truth from the. beginning, viz., that vital force is the life-giving power to all our organs, whether simple or complex. Nutrition and inanition are two contrary processes. The former is re-organizing; the latter, the process of retrogression and decay. The first is a physiological law; the second, a pathological phenomenon; and yet the process of decay is a condition to animal metamor- phosis and life. The process and law of reproduction would not be required if there were no waste, unless we were simply vegetative objects; and with that supposi- tion, we could retain neither our nature nor identity. But as organic life is constituted, an equilibrium between organization and decay is a physical prerogative. If waste in the animal economy should stop, plethora would arise; but if nutrition should cease, waste would reduce the organism to a condition of retrogression and dissolution. Unquestionably these great principles of life and de- cay are constantly and uninterruptedly going on. for they accomplish the great object of uniformity of action and re-action. The subject is undeniably very interesting, inasmuch as it divulges the great and wonderful paths leading to life and vitality—from life to death, and from death to life, from the mere elementary principles of inorganic MAL-ASSIMILATION, INANITION, AND DECAY. 19 matter rising to the highest summit of creation—to an organized body; and more, and higher still, the crown- ing touch of our Creator, i. e., to a sentient being. Whereas when this great uniformity of animal organ- ization ceases, it descends at once to mere matter, and loses energy and force ; and from an organized condition it descends step by step to its primordial state. Nothing is lost! Only the great physical combination of force and activity has ceased, and the elements sepa- rated into different gaseous forms. Existence as a sen- tient being is no more, because the receptacles of the inflowing spiritual life, which is a constant gift from its Author and Source, have separated into other forms. Notwithstanding this process of transmutation, the ele- mentary principles still remain, and return to their original source. But this question would be pertinent: i. e., What becomes of the energy of the nascent force? As a force is intangible and immaterial, it returns whence it came, to that Infinite which no human eye or knowl- edge can ever fathom. We have then reached the last phase of our subject. Our inquiries can go no further, purporting to disclose the spiritual part of our nature. It is proper we should take another direction, more in keeping with our knowl- edge, and let what is not in our province remain where it belongs. It is indeed a ludicrous sight, that of seeing the vain folly and attempts to reach what is and will ever be a secret, or an impossibility for man to discover, as long as he has a mere human nature. Our inquiries have brought us to the problem of cor- relation of forces as indispensable to a perfect organiza- tion. And from this grand ensemble, the beautiful harmony of life arises and exists. It is obvious that the principles of life are now better understood; and we physicians particularly require this great knowledge to enter in the arena of medical and physical science; 20 PROGRESSIVE MEDICINE. and at the same time to form proper conceptions of the etiology of diseases in general. Hypotheses and theories rich in scientific style can easily be produced, but I doubt whether that would be the right way to sound and practical principles—prin- ciples that could be used for the benefit of mankind. The study of diseases must be based upon rational deduction from the knowledge of the human organism, and of its peculiar laws, which guide it in health, so as to come to a proper understanding of the various patho- logical complications that occur from time to time, thus changing its physiological functions. The cases of vitiated blood, nervous and organic diseases, sthenic and asthenic, strumous and lymphatic, physical and functional, mechanical and dynamic, zymotic and contagious, infectious and malarious—these and many others, divided and subdivided by a nomenclature comprehensible only to the physician, they are even to him often perplexities of the most intricate nature. Are these changes from health to disease mere changes in the vitality alone of the economy? No; diseases generally are the results of disordered physiological laws and functions; but as long as the vital force is not seriously attacked, the recuperative power stands against the invasion of morbid influences, and with won- derful activity reproduces strength, and repairs waste, wherever it is needed. The wounds are quickly filled with healthy granulations, and changed from organized matter into living tissues. Is, then, all this done by vital force alone? Decidedly not: it is the result of all the forces together, which go to form physical organiza- tion. These are indeed the primitive and co-ordinal principles of life; and should any interference, no mat- ter how slight in degree, with any of them take place, the most serious consequences may be looked for. And moreover, should the vital force be affected and lessened MAL-ASSIMILATION, INANITION, AND DECAY. 21 in degree, or perverted, the tissues would be lifeless, perverted, or disintegrated; and abnormal formations often thus arise. In curable diseases vitality stands firm against the enemy, although even that may apparently diminish; but it reacts upon the other forces, and the recupera- tive power slowly re-establishes the disarranged equili- brium. Unquestionably, during any physical disturbance from its normal condition, the entire organism suffers more or less, but the stronger the vitality, the stronger is the reorganizing force, and dissolution is prevented. And again, returning to the great pabulum vitae, as the principle by which alone existence can be sus- tained, therefore, on this point, Ave must extend our inquiries, and enter at the same time on the arena of physical diseases, and review them one by one, with all their myriads of symptoms in connection with mal- assimilation and inanition, as well as the process of na- ture's resistance to all morbid invasions and phenomena. Let us select the lymphatic system as the one more prone to temporary or permanent—superficial or con- stitutional—disarrangements, either from physical, or- ganic, or functional causes. From the different pathological complications in the nature of these kinds of diseases, the uniformity of the physical laws and organic functions are more or less disturbed from their normality of action, and thus complications from mal-nutrition, lymphatic atrophy, are produced. When the lymphatic system becomes involved in any physical or functional change, the histogenetic process becomes immediately affected, and the process of nutri- tion and tissue-making is relatively and proportionately diminished. This abnormity soon brings about waste, inanition, and adynsemia. And from these conditions, we are 22 PROGRESSIVE MEDICINE engaged to extricate the human economy, and replace it on its own equilibrium. It is clear, therefore, that our greatest effort, after understanding the functions and laws that are employed in the process of repair, is to assist, rationally and agreeably to nature, the great work of vis-medicatrix naturoz, et vis-conservatrix naturce. The vis-conservative law we study in the first prin- ciple of organic life; the second, or vis-medicatrix, we must find in the proper treatment of diseases, and thus return organic functions to their normal condition and activity. The causes and shades of diseases are so variable and numerous that they often escape the attention of the sufferer, and defy frequently even the skillful physician; and thus diseases frequently remain in a state of latency, undetected and uncured. Some are physical, some or- ganic and functional: some are inherited, others ac- quired. The causes are many, viz., atmospherical, diet, occupation, inordinate mode of living, inheritance, and neglect. Whatever the cause is, there must be a corresponding loss of some of that indispensable harmony which is the only true characteristic of normal action. When the equilibrium of physical law is lost, there must be also a loss of force; hence, physical debility and general dis- turbance. There are two great elements which form the impor- tant process of physical force and equilibrium, i. e., the nitrogenous and albuminous substances derived from the proper articles of diet and converted by assimilation into a proteine compound, whose constituents furnish the plastic elements of life. These nutrients are naturally allied with a variety of elements, i. e., carbon in the nature of amyloids, sugar, and cellulose; having dextrine as the diastase, or the separating element of the different substances existing MAL-ASSIMILATION, INANITION, AND DECAY. 23 in the starch; and these are again classified by the physiologists as respiratory or calorifacient substances, partially histogenetic, but non-nitrogenous. So that starch and albumen are the elements of tissue-making: nitrogenous and saline materials are those of blood making. By the process of molecular and invisible energy we have molecular motion; and hence caloric or absorbed heat. And part of the energy of absorbed heat is spent in pulling asunder the molecules of the body from the attractive force which binds them together; and from this physical and chemical metamorphosis we obtain alcohol by fermentation: C 02 ; and by adding H O2 (water), i. e., one more atom of oxygen, we get lower still, i. e., acetic acid. And so, conversely, we can raise vegetable matter, in the same way, into a higher organic material. So it is plainly demonstrated that we can raise or lower organized matter by the addition of cer- tain organic constituents and elementary influences. Apparently, then, the functions of absorption, secretion, and excretion depend upon several factors, i. e., molec- ular motion, absorbed heat, evolution, and force. These chemico-physical forces bring about physiologico-vital function and nutrition. The chyme and chyle are prepared by gastroenteric juices. These functions are partially chemical and physiological; they assimilate matter to be organized into animal tissues. The process of injestion and ejes- tion takes place under the influence of two organic forces, centripetal and centrifugal, together with the influence of affinity, i. e., endosmosis and exosmosis. This whole physical function means nutrition and repair. The lymphatic system bears a great influence upon the process of histogenesis, while nitrogenous substances are changed into blood. The lymph becomes denser and more viscid as it progresses towards animalization; 24 PROGRESSIVE MEDICINE. and finally it forms into a glandular apparatus through the whole economy. The lacteals are the colaborers with the lymphatics in the metamorphosis of chyle into blood. Each has an elective power, sui generis; but for that I refer to physiology. Thus far we have found that the vital force lies in all organized matter, sponta- neous and independent. And furthermore, the vital force pervades all functions, organic and physical; and there- fore it is possible that the majority of diseases proceed from some dynamical disorder, thus disarranging organ- ization. In consequence of this material disorder of functions, the sympathetic system of nerves must, in more or less degree, suffer; hence the vaso-motor branches excite plethora, or the reverse (anamiia), through two opposite results, i. e., excitability or debility. Thus the pro- cesses of absorption and secretion are changed, and soon a pathological condition takes place. The ganglionic system controls organic functions, and influences the small ramifications called the vaso- motor, which are in reality a continuation of the nervous ganglia. This system has a superlative powrer over our feelings; and causes, when excited, a blush or a paleness during our emotional sensations, and these ramifications reach also the capillaries, the organs of digestion, absorption, secretion, and all the internal organic func- tions. It does more: it reflects upon the organs of special sense, the brain, and organs of generation. The ganglia is the source from which they receive a supplv of force. These ramifications, with millions of invisible subdivisions, play an important part in the process of organization, and in the equilibrium and harmony of the human organism. The chemico-physiological function of digestion and assimilation is often affected by its influence. It is not surprising that this wonderful' phenomenon MAL ASSIMILATION, INANITION, AND DECAY. 25 of physical arrangement is often disordered from vari- ous and innumerable causes, i. e., objective or subject- ive, structural or functional, inherited or acquired. The influence of a simple eruptive disease may make a patient almost frantic with discomfort. When the skin with its glandular apparatus, its capillary convolutions, its pigment, the spongy porosity of sudorific glands, and the groups of papillse and its neurolemma are in an abnormal condition, obviously the reflex action must carry with it a mischievous influence upon the whole economy, as well as upon the hepatic organ. The liver being one of the principal organs involved in the nutritive process, sharing greatly in the organic metamorphosis of the animal system, and having the purification of the venous blood, extracting bile, sugar, and fats, as calorifacients, and its relation to the chylo- poetic viscera, therefore the organ must naturally be prone to abnormal deviations from health in a large degree. In biliary troubles, either in retention or suppression, the process of chylification must be impaired: its hydro- carbo fluid (bile) is a physical necessity to the paristal- tic movement of the muscular fibers of the intestines. It does more: it prevents both fermentation of the ex- crementitious matter and abdominal flatulence. When this carboniferous element is not present, or is not ex- creted, carbonic acid, or sulphuretted hydrogen gas, are sure to be formed in the intestinal canal, showing the beginning of decomposition of the egesta, which, if not corrected, may produce unpleasant complications. The bile renders faecal matter of natural consistency and easily evacuated. But when this hepatic fluid does not pass into the bowels, the fsecal matter becomes hard, lumpy, and of a clay color, showing imperfect digestion; the color often changes to different shades—black, green, brown, etc. 26 PROGRESSIVE MEDICINE The quality of the food used is indicated by the smell of the fecal matter. The nitrogenous food produces an ammoniacal sulphuretted fetid odor; the vegetable food, when undigested, is indicated by an odorless carbonic acid gas. When the bile is retained in the blood (retention), then the danger is of biliary toximia (Icterus). Besides the objective influences causing hepatic com- plications and disorders, the dietetics have an imme- diate relation to hepatic diseases. Excessive nutrition and alcohol produce fatty degeneration and hypertrophy of the organ. I believe an excessive amount of amyloid and glucose articles of diet to be factors of amyloid degeneration of the liver, glucosuria, and fatty dis- integration. Albuminuria often proceeds from mal- assimilation of albuminous food. Organic diseases of the liver are dangerous, because the whole process of nutrition is by them affected, and therefore often incurable. Malarious diseases, or excessive heat, frequently pro- duce hepatic diseases, like atrophy and hypertrophy, from which structural changes, other diseases, i. e., heart, lungs, kidneys, and portal circulation, are likely to occur. In view of this endless chain of physico-vital relations, certain pathological conditions are transferred from one organ to another by sympathetic and anatomical rela- tion, thus creating functional and structural changes, and destroying the harmony of physiological action. The influence of gastric digestion, and the process of chylification—the organic functions of the liver—are two great sources of good or evil. The hepatic organ is also exposed to other influences from various sources, viz., nervous irritability and de- bility—hyperesthesia and asthenia—and even from anaemia. These are all included in the happy expres- sion of adynamia. The contrary of these asthenic MAL-ASSIMILATION, INANITION, A YD DECAY. 27 conditions are, phlogosis, engorgements, stasis, acute and subacute biliary disorders, etc.; and these again may reflex back, as they frequently do, in a great meas- ure upon the process of digestion and assimilation. In such instances the cause and effect are reversed. Facts favor the inference that grief, anxiety, dissipa- tion, and meteorological influences, lower the vital and physical forces; and that all devitalizing tendencies are influential in producing hepatic diseases. In taking a coup-d"ceil of the renal diseases, where the nitrogenous constituents pass out—the urea, lithic acid, and phosphates, sodium lithates and bile—this physical and organic metamorphosis, if in any degree it should be interfered with in its physiological functions, the effete matters would be retained and carried in the circulation; and, indeed, when such is the case, the consequences are serious. It is a well-known fact, that many cases of Bright's disease of the kidneys pro- ceed from mal-assimilation. And many renal diseases are the sequel of nervous disarrangements, hygienic neglect, dissipation, sup- pressed perspiration, checked eruptive diseases like scarlatina, measles, eczema, diphtheria, etc.; also, malari- ous diseases and those of a proteinaceous nature. The old adage is as true to-day as it ever was—Chi va piano va sano, chi va sano va lontano—Moderate and regular habits are conducive to health, while indul- gences, dissipations, exposures, etc., are the factors of disease. 28 PROGRESSIVE MEDICINE, CHAPTER II. PROFESSORS TROUSSEAU AND PEDOUX's ANALYSIS AND CRITICISM OF THE HOMEOPATHIC MATERIA MEDICA AND THERAPEUTICS. These truly conscientious writers have thought proper to review the different schools or systems of medi- cine, from the time of Hippocrates to the present day. They have criticised the French, German, English, and Italian schools, with discretion and justice. The views of Doctors Broussais, Pinel, Brettaneau, Hunter, Brown, Rasori, and Hahnemann, are fairly discussed. They have declared themselves catholic in spirit and eclectic in practice; that is to say, they believe there are many important and useful principles in all the schools of medicine. They saw the difficulty, however, of adopt- ing such a mixture of contradictory theories without run- ning the risk of perplexity and failure; and so they contented themselves with praising what they consid- ered right and true, and disapproving what they thought lacked practical support; but yet they suggested or put forward nothing of their own. It is easy to criticise and pull down what others have built with great labor and difficulty, and quite another thing to raise a new and solid structure of your own. These gentlemen have shown one thing, however, and that is, that the various schools belonging to the " rational" or Allopathic sys- tem of therapeutics, differ from each other as much as they do from homeopathy; and for this reason I confine myself to the criticism they have made upon Hahne- mann's theory of Similia similibus curantur. HOMEOPATHIC MATERIA MEDIC A. 20 They say: " Homeopathy, considered as the general idea upon which this science is based, does not certainly deserve the ridiculous therapeutic distinction which ho- meopathic physicians have imagined that it possessed. When Hahnemann found the therapeutic principle of similia, upon which he stated his argument, he only demonstrated/acfe which were the results of experiments of some of the most eminent physicians of his time. According to Hahnemann," say the Professors, " each medical agent must possess a particular morbid action upon the system; but any drug not possessing distinct pathological properties is not considered a medical agent deserving of our attention. Such propositions are true, but were expressed and demonstrated by others before Hahnemann; and they are worthy of scientific examination, being useful to the science of medicine. The morbid action of medicines can only be recognized by the application of them upon an individ- ual in a perfect state of health." This is so eminently true that Empiricism and Rationalism are both precipi- tated into a labyrinth of obscurity at the appearance of these facts. Artificial diseases, produced by medical agents upon a healthy sj^stem, are recognized and care- fully classified by their peculiar objective and subject- ive symptoms, lesions, and sympathetic complications, which each and every agent is capable of producing upon the animal economy. And when Pedoux said that we "have no orders of symptoms, and no unity," he has shown that he little understood Homeopathy proper. Again they say: " The science of the physician is reduced to purely experimental knowledge, namely, that of the true symptoms of a certain natural disease, and those belonging to a medical agent." Homeopathy, however, does not reject the study of microscopical pathology, and its pathognomonic lesions produced by 30 PROGRESSIVE MEDICINE. natural diseases. On the contrary, it inculcates upon the homeopathic physician the necessity that medical agents should not only give us the superficial symptoms like those of a disease, but also similar pathological, functional, and organic lesions, as well. This knowledge can only be expected to be acquired from toxicology, accidental poisoning, or from experiments made upon animals. These learned gentlemen state the following facts: " When virus is introduced into the system, and finds there homogeneous substances, it multiplies to the in- finitesimal, and infects and assimilates all substances with which it comes in contact. It goes so far that even a single atom of virus is apt to produce similar disease, such as vaccine matter, syphilitic poison, mias- matic effluvia, cholera, yellow fever, and, in short, all contagious diseases." CHEMICO-PHYSIOLOGICAL ANALYSIS. The animal and vegetable kingdoms present us with numberless forms, different from each other in aspect, construction, and function; but the origin of all is the same. All organic bodies differ from the inorganic, or mineral, in the various compositions of their compo- nents, their structure, their proneness to become isomeri- cal, and the great tendency they have to become united in, or change mutually their preference for, one another. The opinion of chemists is very much divided in re- gard to the vital forces which take part in the formation of organic bodies. Liebig compared the vital force to a dynamic power, which has an influence on the organic forces, like caloric. It is known that, with heat, they increase or diminish the changing affinities of organic bodies: therefore they can produce combination, or decomposition, which would not have taken place had it not been for a change of temperature. Liebig also CUEMICO-PHYSIOLOGICAL ANALYSIS. 31 affirms that the normal existence of organic bodies, of whatever being, are, as it were, in the midst of two contrary forces—the organic and the force of affinity. These two vital forces exist in equal parts and strength, and thus maintain the physical equilibrium of either the animal or vegetable kingdom. But when such equilibrium is disturbed by a prevailing influence of either force, life becomes more or less deranged, as this or that influence is prominent. The return of health and vitality is the harbinger of the re-established equi- librium of the two forces. Professor Liebig's experi- ments prove that the current of a liquid is not produced by its want of density, nor by its viscidity, nor by its endowments with the greatest force of ascent in the tubes. But the current is generally determined by the liquid which has the greatest affinity with the inter- posed substance [this establishes the correctness of the law of endosmosis] and " by the greatest rapidity of im- bibition."—Professor Mateucci. A vesicle containing one liquid being placed within another liquid of a different nature, may so act on the one by which it is surrounded as to exchange its own contents for a like quantity of the fluid with which it may be in contact. This explains the law of circulation and nutrition. (See " Physiology.") " Chemists have tried," says Selmi, in his valuable work on Organic Chemistry, " with ingenious and arti- ficial instruments to make mineral matter organic, in the hope of bringing out living beings, and with the aim of producing atoms, that may be, in either effects or na- ture, like those atoms which are part of the organic tissue. Their labor, so far, has been very little rewarded. Chemists have converted cyanogen, ammonium, and carbonate of hydrogen into urea, which is found abun- dantly in the urine, thus uniting purely inorganic sub- stances with means strictly clwrnical." 32 PROGRESSIVE MEDICINE. Any one who has the least knowledge of organic chemistry will soon see that the gains from such chemi- cal experiments have been small. But Professor Selmi says: " It is to be hoped that they would have better success in their experiments and results, if they should undertake a research into the combination of the car- bonated and nitrogenized substances with metalloids." As carbon and nitrogen are the root of all organic com- positions, it is but reasonable to suppose that in both, and particularly in the first, there would exist the power of imparting an organic force into all the molec- ular groups. " Artificial morbid affections are to be placed in the same list with natural diseases, and they do not differ from each other. All natural diseases can be more or less imitated by morbid properties of medical agents, as some of these produce, approximately, symptoms of scarlatina; others, those of apoplexy; others, those of syphilis; others, those of roseola; and others, those of dysentery. A disease produced by a medical agent pos- sesses the power of destroying the natural disease with which it is most similar. Such medical theory would substitute an artificial disease for a natural one, but the artificial disease is only of short duration, and not ma- lignant—on the contrary, perfectly harmless, disappear- ing immediately after a certain effect is produced. We must acknowledge, therefore, that phlegmasia^ or inflam- mations, are cured by the application of irritants, which produce another local inflammation, thus substituting the primitive phlegmasia}; but if it is so with local in- flammation, it is nevertheless not so in general inflamma- tion. But Hahnemann, fascinated by one truth, verv soon exaggerated the importance of his discovery." — Trousseau and Pedoux. In my opinion this is a perfect contradiction, without a satisfactory reason; when acknowledging that a natu- CHEMICO-PHYSIO LOGICAL ANALYSIS. 33 ral disease can be imitated and destroyed by an artificial one. The learned Professors again say: " After knowing the course and intensity of an inflammation, if it were possible to put in contact with the inflamed tissues an irritating medicine, which Avould substitute the existing irritations, a great therapeutic result Avould certainly have been obtained." Such a result is seen in the treatment of conjunctivitis with nitrate of silver, mercurial ointment, or alumina, which are irritating substances. These medical agents are used daily by the Allopathic physicians. They con- tinue: "This fact once established, Ave must study the laAvs of the theory. It is clear, for example, that sub- stances which destroy organic tissues with their chemical or physical action—like lime, mercury, nitric acid, ar- senic, cuprum, lead, and many others—succeed admirably in restoring those tissues, when in a morbid condition, to a healthy state." Doctor Pinel, although not a Homeopathic physician, merely because he lived before Hahnemann, seems to have felt the necessity of treating diseases symptomat- ically, without following the erroneous theory of Brous- sais and Rasori. Symptomology does not mean treating every symptom separately in all cases, as Ave have groups of symptoms; and from groups we form classes. We have groups of miasmatic symptoms, and some for specific diseases; and these groups are divided into classes according to the peculiarity of the miasm, the organic and functional complications, or specific disease. We have also medical agents which produce sthenic and asthenic inflammations, organic and functional de- rangements, etc. These groups are divided into various classes. When Professor Trousseau attempts to demon- strate the fundamental errors of Homeopathy, he must do so on some other ground than by his puerile demonstra- 34 PROGRESSIVE MEDICINE. tion that a medicine can produce certain pathological con- ditions in one organ only, and at the same time admitting that diseases like dysentery, roseola, scarlatina, syphilis, etc., can be artificially produced by medical agents. If our learned professor admits the above as possible, he must undoubtedly admit that a great variety of pathological phenomena can be produced by each and every medical agent, varying, of course, in intensity, in lesion, in specific affinity for certain organs and com- plications. This is all that Homeopathy claims; and it has been so declared by all her followers, Avhose state- ments are based on practical facts. And, I am sure, that all unprejudiced and honest inquirers Avill find the assertion to be true. We ask nothing more than that such men as Trousseau, Avith his candor and his love of science., shall analyze the claims of the system of Sim ilia. Every work on Homeopathy, and every Homeopathic practitioner, is peculiarly solicitous to demonstrate, on clinical grounds, the efficiency of the law of similarity in the treatment of all diseases, excepting mechanical and toxicological, in Avhich mechanical, surgical, and chemical means have to be employed. And in consideration of the honest opinion of Trous- seau upon our system of cure, I have given my answer in a plain, and, I hope, in a convincing manner. I have based the whole Avork on clinical and analytical grounds, to the best of my ability. All the authorities I have searched, of both schools, have strengthened my belief that the day is not far off when the law of similarity will be regarded as the true and only law of therapeutics. The many cures of the hospital and private clinical cases, often authenticated by honest Homeopathic phy- sicians, are unquestionable examples. All morbid influ- ences are as invisible as they are imponderable. CHEMICO-PHYSIOLOGICAL ANALYSIS. 35 Again they say: " We do not deny the divisibility of matter, nor the possibility of its division; but how aro we to determine its division being effective?" I must answer, How are Ave to determine the rotation of the earth? Yet the Avorld moves. I will, however, give a more conclusive answer: We must be logical, and ac- cept results as proofs of Avhat we cannot explain; but still, I think that Ave Homeopathists can ask our brethren to accept physiological and pathological results, Avhich they have already been candid enough to admit and grant to Homeopathy. May I ask the learned pro- fessors how we are to determine the effective power of the luminous bodies of the sun? Merely, they Avould Avell answer, from their effects. How are we to de- termine the amount of morbid influence of miasma ? From its effects. The above argument ought to be sufficient to any unprejudiced mind, that we cannot determine results and effects merely by ponderability of matter. Doctors Trousseau and Pedoux also say: "We knoAV that it is not the quantity of a morbid influence Avhich determines the nature of a disease, nor its intensity, but the kind of poison Avhich has produced the disease— just as it is not the quantity and the size of seed that determine its productiveness. So it is Avith a medical agent—not the quantity, but the kind." I believe that this is sufficient to decide the question of doses, for Avhich the Homeopathic school has been so fearfully abused. And, lastly, they say: "All Homeo- pathic remedies have been tried experimentally upon individuals in a normal condition: the Homeopathic physicians have had the courage, patience, and perse- verance to prove the remedies upon themselves; and have, after manv experiments, succeeded in constituting the Materia Medica Pura from which they have derived much valuable information regarding the specific proper- 36 PROGRESSIVE MEDICINE. ties of medical agents, of A\diich we in France are totally ignorant. Many therapeutic agents are only super- ficially knoAvn to us, as also many diseases Avhich appear under peculiar conditions. In these Ave are at a loss to knoAv Avhat therapeutic means to use." The professors advise that in typhus, typhoid, and other miasmatic diseases, Avhen there are present any of the above peculiar conditions, the diseases should be treated symptomatically. We are indebted to Pro- fessors Trousseau and Pedoux for their criticisms on Homeopathy. Hahnemann's doctrine has never been better explained and represented. DISSOLVING ORGANIC MATTER. Solid or liquid substances, Avhen they unite Avithout chemical composition with a liquid which takes the office of a vehicle or conveyance, do so in one of the following ways, namely, by dissolving, fluidifying, or SAvelling the organic substances Avhich are used as medical agents. It is as much a solution Avhen the substance is dissolved in the conveying liquid, in a state of perfect molecular division, as it would be bv becoming gaseous or ethereal. "The solution," says Professor Selmi, "is only the gasification of the atoms in a certain space that has for vehicle a'liquid, and which is completed by an absorption of caloric." Bizio says: " The dissolved substance does not lose strength in dissolving, in its special quality, neither does it change in the least; and, moreover, it resembles Avhat Ave see in vaporizing bodies." The two substances—of which one is the dissolving agent, the other the dissolved substance—in mixing become smaller in volume, or else they have the con- trary effect, and become much larger; so much so that the volume of the solution very seldom represents the quantity, or real volume, of the matter dissolved. The THE ACTION OF CONTACT. 37 act of aggregation of the liquid and medical agent dis- places a certain quantity of heat equal to that which is absorbed by forming a solution. It is not unnatural that atoms subdivided in such minute particles, not only attract to themselves a part of the precipitating agents, but that they become sometimes so powerful as to dissolve a base from an acid, or a neutral salt into a sub-salt. This sIioavs what poAver division and sub- division can add to organic matter. THE ACTION OF CONTACT. Chemists have observed that, in certain cases, two substances mixed with a liquid react upon each other in such a manner as to modify the effect of one sub- stance by the pressure of the other, Avithout having this substance participate Avith its element in the modification of the first, and that it does not even show any chemical affinity. How do Ave explain the modification of the first substance? The modifying influence of the second substance upon the first is ac- complished by the action of touch, or contact. Berse- lius, Avho Avas the first to call attention to this subject, says: "Besides the forces of cohesion and affinity be- tAveen molecular matter, there also exists a third force, called catalectic, or catalysis; and from this peculiar force Ave can explain the action of touch or contact. Catalysis is a peculiar influence or force of a body Avhich modifies other bodies by mere contact, Avithout itself undergoing any change." This, in my opinion, is sufficient evidence that Dr. Algeidi Avas correct Avhen he Avrote a letter to Hahnemann, in Avhich he said: "The combination of two medical agents has proved, beyond doubt, that their therapeutic action is increased without either altering or neutralizing the other, provided such agents are not incompatible." Another proof that Homeopathy is based upon the 38 PROGRESSIVE MEDICINE. most scientific laws of chemistry is the following: the atoms of an active body become much more effective in their influence through the velocity of their movements, and the force with Avhich they move. In other words, atoms gain more active strength by rapid motion than by the quantity of particles which such bodies may contain. Here Ave have another conclusive and rational example: Ave produce coagulation of a hundred thousand parts of Avarm milk in the space of half an hour, Avith one part only of caseine, Avhich Avould be less than one sixth of the active agent. It is but reasonable that Ave should attribute that wonderful phenomenon of coagulation to the velocity of the molecular movement of caseine rather than to the quantity of ingredients therein. This demonstrates, beyond doubt, hoAv much rapid motion of molecular matter can accomplish. Liquids, by the means of adherence, absorb and condense many ethereal fluids. The power of condensation is exhausted to such a degree as to become a Avondsrful phenomenon. They come to the conclusion, from the observation of Pro- fessor Hassenfratz, that the volume of a solution does not represent the real volume of the dissolving agent, nor of the substance dissolved—having either dilatation or contraction. But it is to be supposed, according to the elementary laAvs, that caloric and motion will always dilate an ingredient which is undergoing the process of subdivision. •EFFECT OF FRICTION UPON MEDICAL AGENTS. The first action of friction is to increase the volume of organic bodies and produce heat, and thus disinte- grate solids. Solids and liquids both go through the process of vaporization when acted upon by heat. There is a great number of substances which become decomposed and useless, if exposed to heat and light. It has been observed that light produces evaporization DEVELOPMENT OF ORGANIC MATTER. 39 of some organic bodies—for example, camphor; and it is well known that it discolors many substances contain- ing a coloring matter, by exciting the oxygen of the atmosphere to act upon them, or to become mixed with them, or else to neutralize the hydrogen contained by them. It is well known that oxygen sometimes becomes attached to the atoms, like a metal; and in that case, such atoms become oxydized. At other times, oxygen takes off the carbon and the hydrogen; and it can do this without mixing itself with the substances which it has decarbonized and dis-hydrogenized. This shoAvs the error of keeping medical agents in the light and heat. In Homeopathy, Ave have a rule that our medicines should be kept in a dark and cold room. THE DEVELOPMENT OF ORGANIC MATTER. We can see, at the first vieAv, that the developing force, par excellence, of the organic attitude of the princi- pal elements is hydrogen. Hydrogen produces volatil- ity of the organic compounds: the more hydrogen, the more development, and the more volatility. The quan- tity of water does not diminish the organization of the organic bodies. Water is a simple developing agent, and is neither an organizing nor disorganizing agent. The importance of water, in organic chemistry, is almost equal to that of carbon. Water—in dissolving, sub- dissolving, emulsionizing, and gathering all the organic bodies—favors the reactions, modifies the quality, and prepares them to accomplish the functions, to Avhich the vital force stimulates them. Without Avater, Ave would have neither blood, lymph, nor many other in- gredients belonging to both the animal and vegetable kingdoms. Finally, there would be neither organiza- tion nor life. The subdivision of the elements in favor of organic atoms brings great changes, and these are produced by the formation of new substances contained 40 PROGRESSIVE MEDICINE. in the Avater. This confirms the hypothesis that water is a developing agent, if not an organizing one. ELECTRIC IRRITABILITY OF THE NERVES. 1. Electricity is the only irritant Avhich can excite at one time sensation, and at another time contraction, according to the direction in Avhich it transverses a nerve. 2. The electric current alone, in passing trans- versely across a nerve, produces no phenomena due to the excitability of the nerve. 3. The electric current has no effect on the nerves; that is, it neither causes contraction nor sensation, Avhen its action on the nerve is prolonged. 4. The electric current alone modifies the excitability of a nerve, and even rapidly destroys it, Avhen the current circulates in a certain direction; and can preserve or augment the excitability, Avhen passing in the opposite direction. 5. Of all the irri- tating agents, the electric current is the only one Avhich possesses the poAver of reviving the excitability of the nerves, for a time, Avhen they have become very much enfeebled in respect to other stimulants. ANALOGY BETWEEN ELECTRICITY AND NERVOUS FORCE. These differences betAveen the action Avhich elec- tricity exercises on the nerves, and the action of other irritants, evidently show that the first is more simple than the last. Hence arises the analogy between the nervous force and the electric current, which the earliest observers of galvanism faintly perceived. But ought we, from this analogy, to conclude that the nervous force is merely an electric current? Let us be cautious in as- suming such an inference—which is too often adopted as one of the best demonstrated experimental truths. It was important to search for the presence of an elec- tric current in the nerve of a living animal. The most conscientious and best-established conclusion, is this- ON THE SECRETIONS. 41 In the present state of science, and Avith the means of experimenting Ave noAv possess, no sign of an electric current is found in the nerves of human beings or of the lower animals. What is the relation existing be- tween nervous force and electricity? There exists between electricity and nervous force an analogy, Avhich, if it does not possess the same degree of evi- dence, is, hoAvever, of the same kind as those analogies Avhich Ave know exist betAveen caloric, light, and elec- tricity. The phenomena which Ave have observed in electrical fishes prove that a link of the same nature unites the nervous force and electricity. Electricity is not nervous force; nor is nervous force or caloric electricity. There is a beautiful analogy of the tAvo forces Avritten by Professor Mateucci. The conclusion of this interesting argument, that " two forces may be alike, acting upon one another Avith advantage, and yet not the same," is a very important matter, and Avorthy of attentive study by all Homeopathic students. It is Avell to knoAv it, and to knoAv it scientifically. Professor Mateucci goes on to shoAV Iioav electricity can excite nervous force. The excitability of the nerves can also be aAvakened, and sensation of muscular movements determined, by other agents as Avell as by electricity; for example, by heat, and by mechanical and chemical action. In all these actions Ave can only see various causes of molecular movement, etc.; and Ave cannot say that chemical and mechanical force and caloric are either nervous force or electricity. But they are analogous in their actions and results. ON THE SECRETIONS. Bv secretions, Ave mean the different fluids Avhich are formed in the organs at the expense of the blood. These fluids have different actions in the animal economy. Some are destined to certain functions, as the saliva, 42 PROGRESSIVE MEDICINE bile, pancreatic juice, etc. Others are thrown out, like perspiration, urine, milk, etc., because they could not remain in the economy without producing much de- rangement. The secreted liquids have a variable com- position. Some are, as it Avere, evaporated on the sur- face of the membranes Avhence they come; such are the mucus, perspiration, and the serum. Others are the saliva and the pancreatic juice: these latter are ac- cumulated in particular ducts, Avhich pour them out when needed. Finally, some others are immediately placed, after being secreted, in particular reservoirs; such as the bile, the urine, and spermatic fluid. All these secretions are not formed by the secreting organs, but by the blood itself. This proof shoAvs that there is no such thing as secreting membranes; but that they only perform the mechanical function of eliminating such fluids from the blood; and these once throAvn out of the general circulation are of no more use to the nutrition of the system, and are then received into the membranes for other purposes. This idea is not agreed upon by all physiologists. They have taken out the kidneys of a dog, so as to pre- vent the secretion of urine and the excretion through the usual channel. After a few days the dog died, and they found that the blood contained urea; but it has been impossible to ascertain such phenomena in a case of natural death, as undoubtedly the kidneys constantly separate the urea from the blood. First, the separation of matter from the blood is performed by filtration; and second, by cell-action, etc. Secretion by filtration is purely a physical act, which is closely demonstrated in the case of the. lachrymal glands. This mechanical function is observed also in the serous, and particularly in the synovial membranes, and bursce mucosae. As long as the material secreted pre-exists in the blood, it is needless to refer secretions to any other principle' than to the simple one of transudation and filtration. This THE SALIVARY GLANDS—CHYME. 43 law is well defined in the structure of the liver; that is to say, four different vessels are engaged in the liver— the portal vein, hepatic arteries, biliary duct, and he- patic veins. The first tAVO are the afferent; the second two, the efferent. The portal vein brings the portal or venous blood. The arteries supply that organ Avith the necessary blood for nutrition, that is,Avith arterial blood. The ducts carry off the biliary secretions Avhich have been separated from the blood. The hepatic veins take charge of the residue, and carry it back into the circula- tion and into the vena-cava. Similar processes take place throughout the glandular system. SECRETION OF THE SALIVARY GLANDS. There are, it is Avell knoAvn, three pairs of salivary glands; and although secreting similiar fluids, yet they are not the same. The parotid fluid differs from the maxillary in density; and is less alkaline, and contains less lime. It is so viscid and glutinous that it may be draAvn into threads; but the sublingual is much like the parotid fluid. Besides the special juices, the mucous membranes pour forth a liquid of a thick, tenacious character, Avhich is alkaline in its reaction. The mucus of the buccal mixed with the submaxillary secretions, accomplishes a transudation of starch into sugar Avith facility, Avhich it Avill not do Avhen mixed Avith the par- otid fluid. The saliva of the mouth is a compound of the secretions of the various salivary glands. The pre- ponderating ingredients in the composition of the saliv-a are sulphates, chloride of sodium, and potassium. The difference betAveen the saliva of man and that of herb- ivorous animals is only that the salivary-calculus of man contains a greater quantity of phosphates. ON CHYME. Chyme is the result of digested food. In consistency, color, and chemical re-action, chyme varies with the na- 44 PROGRESSIVE MEDICINE. ture of food, in its chemical constitution and its quantity, but under ordinary circumstances presents an acid re- action, for it is to be remembered that the diurnal sup- ply of hydro-chloric acid is about one-fifth of an ounce. Pepsin is a very important agent in the accomplishment of digestion. The following is an example : hydrochloric acid has been kept in contact with albumen, without any perceptible action, at an ordinary temperature; but if the same acid,-at the same degree of temperature, be joined Avith an addition of pepsin, a solution takes place with rapidity. This is sufficient to explain the influ- ence of pepsin upon the digestion; that is to say, by replacing heat. The acid alone cannot form a solution Avithout an increase of temperature varying from 150 to 200 degrees. The lactic acid, by the aid of" pepsin, reduces the food to a uniform pulpy mass, called chyme. Of all the acids, these alone are capable of forming digestive fluids. GASTRIC JUICE. Gastric juice is secreted by the internal coat of the stomach, and has the power of dissolving the ingredi- ents Avhich enter into that organ and of changing them into chyle. Physiologists and chemists, after many ex- periments upon dogs, etc., have come to the conclusion that the acidity of the juice is due to an acid identical Avith the lactic and ascetic acids. Dr. Prout has demon- strated that the free acid is hydrochloric acid. This acid of the gastric juice and the soda of the bile are de- rived from common salt, which is present in the food. We find that there is a constant recurrent periodicity of digestion from the mouth and the entire digestive track. As to the particular usefulness of this juice upon the ingredients of nutrition, Professor Spallazani believes it to be the dissolving agent, Avithout which no perfect digestion would take place, and no molec- ular transformation of chyme into chyle could be PANCREATIC JUICE, ETC. 45 accomplished. Thus Ave must regard the gastric juice as one of the great principles of digestion, and an in- dispensable substance in the formation of chyle from the milky emulsion of chyme. PANCREATIC JUICE. That fluid Avhich is called pancreatic juice is secreted by the pancreas, and poured into the duodenum to- gether Avith the bile and gastric juice. The secretion of this gland is similar in composition to that of the salivary glands, and its structure is also similar to the salivary glands; and hence it is usually regarded as one of the group. The juice itself is analogous to saliva, being viscid and alkaline in its reaction. Its specific gravity is 1.008. It acts upon starch even more ener- getically than saliva, transforming it into sugar and lactic acid; and upon fats, by forming them into emul- sion, so that they are readily absorbed. This has been proved by submitting fatty substances to the juice at the temperature of 100°. HoAvever, the action of the pancreatic juice seems to be limited to the upper half of the intestines. ENTERIC JUICE. This juice has received but very little attention from the medical profession in general; and, in my opinion, it is one of the most complicated, as Avell as one of the most useful, in its character and function. It is secreted by Brunner's glands, the structure of Avhich has a cer- tain analogy to the salivary group. These glands are found in the upper part of the small intestines: they are as small as a hemp-seed, and consist of globules with ducts communicating with a common outlet. Their secretion possesses a more energetic power in forming fatty emulsion Avhen mixed with bile and pancreatic juice than the pancreatic juice alone. In the opinion of Dr. Schmidt, the intestinal juice, which they describe 46 PROGRESSIVE MEDICINE. as being invariably alkaline, exerts as poAverful an action on flesh, albumen, and other proteine bodies, as that which occurs in the stomach itself. The follicles of Lieberkuhnn are straight, narrow, cereal depressions of mucous membranes, found all over the intestines. They are analogous in their structure to the mucous follicles of the stomach, Avhich secrete pepsin; and it may be presumed that they possess similar functions. Their mouths open to the intestines, to Avhich they com- municate their influence. There is another very important class of glands, or paches. These are circular spots of a Avhitish color; and, without any excretory ducts opening into the intes- tines, they secrete some kind of fluid necessary to the intestinal digestion. By some it is denied that these' bodies are in any way connected Avith intestinal diges- tion ; but it is too absurd to suppose that these little glands have any other function than that of a fluid, Avhich, like the mucus of the mouth, possesses some in- gredient necessary for the accomplishment of di- gestion. SYNOVIAL FLUID. This fluid is furnished by a particular membrane which forms the synovial capsules of the articulations, and is secreted for the purpose of facilitating the fric- tion of articular surfaces. This fluid has been analyzed, and found to be semi-transparent, greenish, viscid, and filamentous, like the Avhite of an egg; greasy to the touch, and saline in taste. Left to itself it assumes a gelatinous consistency. It becomes fluidified after de- composing a fibrinous substance. The synovial fluid of man contains a great quantity of albumen, animal matter, alcohol, a fatty substance, some soda, chloride of sodium and potassium, and phosphate and carbonate of lime. The knowledge of the different ingredients composing this fluid is of great importance to the physician, as they LYMPH, ETC. 47 have considerable influence upon the diseases of the articulation. LYMPH. The lymph is a serous fluid, very abundant in the human economy, and is the result of the process of de- composition of the blood; or in other Avords, it is a sepa- rated constituent of the blood. It is found in the white corpuscles, or mixed with chyle in the thoracic duct. The lymph, like all the other fluids, is secreted by the capillaries; and, in its composition, is like the blood itself, except in the red cells—the fibrine, albumen, and saline constituents being apparently the same. The lymph collects all the albuminous matter throAvn out by transudation from the blood, as unnecessary or innutri- tious ingredients. These albuminous ingredients, being allied to the lymph, form a glandular substance, Avhich is called the lymphatics. This structure is the counter- part of the mesenteric or lacteal glands. These lymph- atics anastomose with each other, in various Avays, so as to form plexuses and convolutions. The action of the lymph is to gather the albuminous substances thrown out by the blood-vessels, which otherwise Avould go to waste. Receiving all these, they transmit them through their Avindings in the glands, and then submit them to the action of innumerable cells; and, as in the egg of a bird, albumen disappears and muscular tissue of a bird arises, so here the serous portion disappears and fibrine arises in its place. This is carried forward into the circulation, to repair the great waste of muscular tissue. The skin is abundantly supplied with these glands, or lymphatics. FLUIDS WHOSE REACTION IS ACID. The skin contains tAvo kinds of glands: one for the removal of water, the other for the removal of oily sub- stances. Dr. Anselmino analyzed the vapors, or steam, 48 PROGRESSIVE MEDICINE. of the body, and found the folloAving features, namely, the fluid itself is perfectly clear, and has no smell; but when analyzed it was found to be composed of Avater and carbonic acid. ANALYSIS OF PERSPIRATION. The skin permits Avater and saline and fatty sub- stances to escape from it in quantities Avhich differ on different parts of the human body. The experience of Dr. Berzelius gives us the following substances as com- posing the human perspiration: water, acetic and lactic acids, chloride of sodium, potassium, phosphates, and oxide of iron. The acetic acid is the fluid Avhich acts upon colored clothing. Whatever physical circumstances promote surface evaporation correspondingly promote the action of the skin. Moreover, this membrane acts similarly Avith the kidneys; and this not only in regard to the Avater, but also in regard to the solid matter, a certain amount of which is thrown off in the space of twenty-four hours. Besides Avater secreted by the sudoriparous glands, car- bonic acid and nitrogen escape. Their proportion is variable and seems to depend upon the nature of the food—carbonic acid increases Avith vegetable food, and nitrogen with animal food. Professor Draper says: "I believe that the sudoriparous glands are the counterpart of the malpighian bodies, and the sebiparous glands are the counterpart of the uriniferous tubes." Besides ex- ercising the functions of exhalation and perspiration, they also exert a great absorbent action. Liquids, as Avell as gases, find entrance through the skin. If oxy- gen, carbonic acid, and nitrogen are put in contact with the skin, absorption rapidly ensues. MILK AND ITS COMPOSITION. The proportion of water which exists in milk is about nine-tenths of the whole amount. The function of the CONSTITUTION OF MILK, ETC. 49 Avater is to remove from the system substances which are not of a vaporous or gaseous form, and Avhich cannot escape through the lungs and regulate the temperature by evaporation, and to impart fluidity to the blood. These are conditions as necessary to the infant as to the adult; and it should be remembered that tAvo-thirds of the Aveight of the body is water. The next most important ingredient of milk is caseine, Avhich is the tissue-making, histogenetic, or nutritive element. It is to be converted into the muscular, gel- atinous, and other soft tissues of the infant. What is meant by proteine bodies is caseine, one of the group designated by Professor Draper as the neutral nitro- genized bodies, of Avhich albumen, fibrine, and globuline are the most prominent substances, and Avhich form the so-called proteine bodies. Of the whole group, albumen is the most important element; but it will be seen in physiology that the process of digestion converts the other substances into it. Caseine, albumen, and fibrine all present nearly the same constitution, but differ from each other in their physical properties. CONSTITUTION OF MILK. Goat's milk......Caseine, 80.....Sugar, 40......Butter, 40. Cow's milk....... " 60..... " 28...... " 40. Woman's milk.... " 32..... " 36...... " 29. This table sIioavs hoAv often the changing of milk interferes with the process of nutrition. Goat's milk, in my opinion, is the best substitute for human milk for children. INFLUENCE OF AGE ON THE COMPOSITION OF MILK. The variations in the composition of milk from its normal standard depend upon age and bodily health. Young females, from fifteen to tAventy, yield a milk more rich in solids than that Avhich is given at thirty-five or 50 PROGRESSIVE MEDICINE. forty years. (See " Physiolgy.") This is a very import- ant subject to the physician, as he is often consulted by his patients as to his opinion in regard to milk most suitable for children who cannot nurse. The opinion of the physician, in this case, ought to be based upon his thorough knowledge of the composition of milk and its changes, PREDISPOSING CA USES TO MENTAL DISEASES. 51 CHAPTER III. PREDISPOSING CAUSES TO MENTAL DISEASES. It is unquestionably accepted as a natural result that all great efforts, either physical, organic, vital, or mental, are more or less destructive to organic structure and functions. Such efforts are always followed by reaction, loss of equilibrium, and harmony of action. Mental efforts are not exempt from the general law, which produces reaction, debility, irritability, spasmodic or tetanic disorders, or anaesthesia, partial and general paralysis; in consequence of Avhich disorders of circu- lation and organic functions must unavoidably and frequently occur. On the contrary, if the organization, or any of the vital functions of the organic economy, should be inter- fered Avith, either by Avant of proper nutrition (anaemia), or hypernutrition (plethora), the reflex influences upon the encephalon are those of a pathological nature, thus disarranging the physical phenomenon of life and its modus operandi. Sleep brings rest and restores the organic economy to its normal condition. Labor means action and mo- tion, and if exhaustive, irritability, insomnia, and loss of appetite generally folloAvs. The brain has various and complex duties to perform, viz.: sensation, creative-poAver, and volition, and supplies physical and vital forces, besides the general functions of thought, Avhich must be controlled by the effort of the great nerve centre. Mal-nutrition, continued Avasting diseases, infectious, 52 PROGRESSIVE MEDICINE. malarious, zymotic, sthenic, asthenic, and many other diseases, may involve the nervous centre to such an extent as to produce mental aberration, hallucinations, exhaustion, irritability, monomania, and finally insanity. These are proximate and predisposing causes. The exciting causes may be thus mentioned: Grief, loss of property, loss of friends and relatives, fright, great excitement, blighted affections, poison, injuries, dissipation, excess in venery, anaemia, and inanition. The remote and physical causes are inheritance, scro- fula, renal diseases, epilepsy, chorea, retrocession of skin diseases, hepatic structural disease, etc. It is necessary that Ave should return to our special subject of inquiry, i. e., mal-assimilation and inanition, as amongst the factors of mental derangement. No doubt that mal-nutrition is often a cause of derange- ment of the organism ; hence inanition, haematic change, and asthenia; these Avould soon produce a dissolution of the organizing process of all the physical and vital func- tions. And if Ave accept this as a true axiom, Ave can thus Avell accept the theory of anaemia of the brain. A Avant of proper general nutrition must exercise a depressing influence upon neuro-plasty and mental force. Starvation and plethora reach, though through oppo- site causes, the same unavoidable end, i. e., mental dis- ease. When the mental functions are once incapacitated, their normal, physical, and vital condition is seldom re- covered. The brain has greater and more complex Avork to perform than any other organ, and has no tem- porary substitute to act in its place. Act it must, sick or Avell, as the energies of all the physical and organic functions depend upon it. Those Avho are more prone or predisposed to mental metamorphosis are literary and professional men gen- erally; and just here, they may occupy our attention principally, because they form a large number of our PREDISPOSING CA USES TO MENTAL DISEASES. 53 daily patients, suffering from various nervous affec- tions. Though their occupations necessarily differ or vary in character, those Avho perform the arduous mental labor of the Avorld are the metaphysicians, mathema- ticians, engineers, philosophers, historians, physicians, lawyers, musicians, actors, statesmen, clergy, etc. This class of men, Avhose mental energies and resources are put to the heaviest tasks, too often neglect their physical necessities, to a great and dangerous extent. In such cases, naturally, the vital force must suffer from such deleterious neglect and overwork, thus implanting diseases, organic or functional, on some parts of the nervous system. These abnormalities may fall upon the motory or sensory system, or the triple system of nerves, i. e., sympathetic, vaso-motor, and splanchic. Disintegration of the cells, embolism, thrombosis often occur. The Avorld owes much and has received much and untold benefits from this class of men; they have raised the human family above the drudgery of mere vegetative creatures; they have ennobled us and keep us moving fonvard in the proper sphere Avhich God has intended us to fill; and they thus enable us to ascend to that higher plane of intelligence and culture which the Infinite has designed that Ave should reach. This great and glorious Avork must Avear fearfully upon the great centre, the brain; and so the nervous forces, cen- tripetal and centrifugal, must, pari passu, be renovated and constantly nourished with the proper elements of nutrition. Should it be surprising that the organs of repair are at times affected by these great mental efforts? It is obvious that the mental phenomenon would, in such cases, receive a doubly devitalizing and depressing in- fluence, i. e., one from an over-use of mental faculties, and another from a want of proper nutrition and repair. Inasmuch as all vital processes depend upon a state of 54 PROGRESSIVE MEDICINE. perfect physical equilibrium, it certainly is very evident that the organs of alimentation must perform their duty and be in a perfect physiological condition. Even Avere nutrition alone rendered feeble and in- sufficient, the Avhole economy (brain included) must suf- fer and finally become totally disabled. The morbid conditions that naturally result from either or both disorders, i. e., brain and digestive organs, or, vice-versa, digestive organs and brain, are obviously unlimited, according to idiosyncrasies and diathesis. Some may suffer only from mere hyperaesthesia, hyper- aemia, etc., others from exhaustion and inanition. A large number of persons suffering principally from enfeebled digestion and imperfect chylification, consti- pation, and torpidity of the liver, etc., are rendered incapable of severe constant mental occupations; these are often the products of the sedentary life of students. LikeAvise renal troubles may supervene; the skin and its functions often become altered and throw back the excrementitious materials which ought to have been eliminated. The secretions are changed, and hence the lymphatics become surcharged and engorged, and thus caco-plastic elements and neophites are formed (hetero-plastic lymphoma or neuro-hetero-plastic). All persons that pass their time in seclusion are neces- sarily deprived of the needy and healthful exercise —fresh air and motion—excluding those elements that are so important to perfect organic metamorphosis, Avithout which, sooner or later, life becomes seriously affected. And, to make matters Avorse, these people have supple- mented artificial substances for natural and life-giving elements, in the form of stimulants: as coffee, tea, liquor, high condiments, and in this manner live on an artificial stimulus whose reaction is sure to take place in debility and exhaustion. Now, therefore, since Ave have seen the practical folly of substituting artificial agents, we HYGIENE, DIETETICS, AND THERAPEUTICS. 55 must endeavor to correct these abuses and supply a better and more rational proceeding. HYGIENE. Firstly. We must remove the patient from a seden- tary life, and give him exercise in the open air, plain, nourishing food, light, heat, electricity, and regular hours for eating and for rest, also salt-Avater baths, cheerful company and sufficient Avork to preArent another evil—the despondency that follows idleness. DIETETICS. Secondly. The dietetics must be prescribed according to the idiosyncrasies of the individual. If he is emaci- ated and anaemic, he should have animal food and nitro- genous vegetables, containing those elements Avhich the patient requires. The diet should be at times amylaceous, mixed Avith succulent substances. If he requires food for the nervous system, give him fish, eggs, wild game, and poultry. THERAPEUTICS. Thirdly. The therapeutical agents must also be chosen according to the constitution and special re- quirements. In these cases Ave find adynamia the superlative symptom and then a neuro-phlogosis may be found in some organs, but generally there is anaemia accompanied by asthenia. Then our remedies must be of a vital nature, reorganizing and reinvigorating— ferrum phosph. et per oxidum, ferrum sulphuricum, ferrum iodidi, etc. And, again, our blood remedies are natrum and kali phosphoricum or sulphuricum, magnesia phosph., oxid. of manganum, natrum chloricum. In cases of nervous debility our remedies are phos- phorus, cinchona, quinia, zincum oxidum, nux vom., strychia ignatia, pulsatilla bryonia, actea racem., arnica mont, etc. 56 PROGRESSIVE MEDICINE. And in those cases Avhere there are complications of the digestive organs, so called difficulty of the chylo- poietic viscera, podophyllum, mercurius sol. or alkali- zatum, aloes, rhei et natrum, Kissengen Avater, sulphur, arsenicum alb or alkalizatum (the liq. potassae arsenica- lis), bismuth, and pepsine. These remedies must be changed according to the many circumstances,i.e., age, sex, occupation, idiosyncrasies, and diathesis, but they are sufficient for all common purposes; and are in a measure the best remedies. The object is that of logically inA'igorating and sup- plying the system with those elements needed, and, at the same time, disintegrating tlie carbonic acid through the lungs, skin, or excretions. In all complications Ave must make a strong distinc- tion betAveen organic, sympathetic, and functional dis- eases. The differential diagnosis is of the utmost im- portance, as it Avill be obvious to every practitioner that objective and subjective symptoms form the train of diagnostic signs, Avhich united give shade, and form the true type of the disease in question. Causes and struc- tural pathology are indispensable diagnostics, as evi- dences of an undoubted nature concerning the true physically morbid condition existing. For illustration, in diseases of the liA-er one of tAvo disorders may be presented under very similar signs and etiological condition, i. c, suppression and retention of bile. The former is an organic derangement; the latter is a functional'one. The same is the case Avith the kidneys; the evacuation of urine may be impeded, should Ave therefore jump at the conclusion that Ave have a mere case of retention, Avithout any further inquiry? The evidences are in favor of the folloAving conclu- sion: intellectual occupations favor diseases of the nervous and digestive systems, from which those em- ployed in mechanical labor are entirely exempt. In the former instance sedentary life prevents proper THERAPEUTICS. 57 oxidation and elimination of carbonic acid; Avhile in the latter it. favors oxidation, organization, and elimina- tions of the excrementitious material. Nutriment can- not Avell be assimilated and organized unless done through the physical and physiological functions of elementary and mechanical forces, i. e., motion, heat, air, light, and electricity. And undoubtedly the prc- teinaceous compound cannot become plastic matter Avhen the above organizing physical principles are Avanting. And besides these elementary principles of life, others equally as important are the elements of nutrition, Avhich, notAvithstanding their possessing all the con- stituents required, the art of preparing them is surely of great import, for it develops their nutritive con- stituents, Avhile otherAvise it might destroy them so as to become useless as elements of alimentation and repair. Cooking is an art that may prove either salutary or injurious, and the health and happiness of millions of people depend to a great measure upon the knoAvledge of this accomplishment. It is a Avell-knoAvn fact that a great deal can be done by a good nurse and cook. The former is to knoAv how to apply Avhat the latter has studied Iioav to prepare. A judicious diet may be often the means of restoration of the physical forces. The same nutriment cannot be used ahvays for even the same patient; it must accord Avith the nature of the disease and the requirements of the system. Even during the same sickness the diet must be constantly and intelligently varied. The various lights and shades of nervous^affections change so frequently, and present themselves in so many various forms, that the most skillful of diagnosti- cians is often puzzled to recognize the old enemy in its neAv garb. Empiricism and mere routine practice should be 58 PROGRESSIVE MEDICINE. deprecated as dangerous and umvorthy of the honest and scientific physician. Nothing is more imperatively demanded than conscience and honesty in the physician. There are no forced boundaries, no forbidden path in the acquirement of his knoAvledge and to his honest convictions; no school or teaching should debar him from the privilege of inquiry and study of other theories besides his OAvn. Knowledge has no line of demarca- tion; it is a sea Avhere the most experienced navigator may always find something to learn. Surely, notAvithstanding a perfect liberty of action and conviction, care should be taken that vagaries, mysticism, and follies should not misplace the Avell- knoAvn facts and rules adopted by sound-minded men, and tested Avith the crucible of experience and practice. The elements of nutrition, then, must be particularly selected so as to accord Avith the principles of life and repair. When oxidation and decomposition are impeded, or partially interfered Avith, the process of combustion or fermentation (heat, assimilation, and nutrition) becomes difficult and inefficient. It is then necessary to measure the physiological requirements of our patient. Knowing one's habit, diet, idiosyncrasies, and consti- tution, Ave Avould know, or should knoAv, Avhat to pre- scribe and Avhat to forbid. It is a general rule, that cases of nervous ailment require very light nourishing food; and at times very strong and in small quantities, Light food may be enumerated as follows: fish, eggs, nitrogenous and vegetable food, Avine, cream, shell-fish, broth, etc. Strong food—beef juice, soup of vegetable and shell- fish, roast beef, game, eggs Avith rum and sugar and Avater, ale Avith yolk of an e^, coffee and cream, cocoa and Avell done oatmeal, peas, beans, and lentils. The amylaceous, glucose, and succulent elements of THERAPEUTICS. 59 food Avould not supply the requirements of those diseases belonging to asthenia, inanition, or adynaemia. And it is proven that nitrogenous and carbonaceous are the most suitable nutriment for an exhausted or emaciated constitution. Changes are necessary, and oftentimes in favor of a starchy vegetable diet; but this comes in as a substitute for producing caloric and fat. Sago, rice, potatoes, turnips, corn meal, tomatoes, barley, tapioca and fruits—these must be cooked so as to destroy the elements of fermentation, breaking every cell and preventing the descending tendency of these vegetables into carbonic acid. Add coffee, tea, cocoa, wines, and we have all the substances that help nutrition and physical metamor- phosis. These beverages have been instituted for the purpose of nutrition, by preventing tissue Avaste. Nothing adds more to an intellectual Avorker than a cup of coffee and cream. It not only supplies a stimulus, but it does more: it supplies food by its nitrogenous constituents, and prevents a quick Avaste of vital force. Tea, on the contrary, proves to be a respiratory fluid; increasing respiration by acting upon the vagi, and pneumogastric nerve, thus eliminating carbonic acid in greater quantity. Tea is a stimulant Avhich possesses, in very small quantity, nitrogen (thein), and helps the system to burn out carboniferous materials in the form of carbonic acid. Therefore the indications of both remedies are, the former to increase nutrition, the latter to increase ejestion; one to support nature's debility, the other to enable her to eliminate the poisonous ac- cumulations (secretory ingredients) and perform that elimination. In conclusion, dietetic experiments have demonstrated that a smaller quantity of food is required Avhen these fluids are taken than Avhen they are not. In old and infirm people, Avhere the desire for tea is so strong, the 60 PROGRESSIVE MEDICINE. Avaste and decay of the system is thus lessened by its use. Coffee Avould be still better. Professor Liebig says: " With addition to oxygen and Avater, they can yield tourine, Avhich is the nitrogenized constituent of bile. In their complexity it is very probable that they act as a part of food to the exciting and vivifying of strong common soup, and that coffeine and theobromine are closely related in their composition to nervous elements, and therefore they are suited for the repair and renovation of the exhausted brain." And here Ave stumble into the great question of tem- perance. Are spirituous liquors beverages and a physical necessity? As to their being beverages, in the usual acceptation of that terra, they certainly are not; they are agents by which certain beneficial results can be produced Avhen there is a physical necessity, i.e., in sickness. As elements of nutrition and oxidation, there are none superior Avhen the animal economy is tardy in her functions of reorganization and repair. We are informed from experiments made by good authorities that plastic formation must go through a certain grad- ual metamorphosis, and this is obtained by a process of fermentation, decomposition, and disintegration, so as to again become organized into a higher state of formation. Thus starch, sugar, and dextrine, the constituents of ATegetable matter, Avill by fermenta- tion become plastic formations, making the so-called protoplasma. And by a continuous process, Avith an addition of oxj'gen, alcohol is formed; or Ave may push the vegeta- ble disintegration of elements still further, into acetic acid, and from that into yeast or mold. Thus the vivi- fying principle of the vegetable matter is, par excel- lence, the diastase or malt, and so are albuminous constituents, Avhich exist in more or less degree in all vegetable and starchy products, but which require heat THERAPE UTICS. 61 and moisture, together Avith molecular motion to bring about atomic force and organization. The ferment, then, is the result of a condition, the presence of the mold, the principle in Avhich the force exists, the latent force of the yeast or mold. There is, therefore, the principle of life in the matter itself; and this is the true vital force. There is another question: Is, then, fermentation necessary to organization? Yes, to a certain extent. All vegetable nutriments contain a diastase or germin- ating principle that converts their starch into gum and sugar, and this is done through the developing process of heat and moisture, hence the result is fermentation. The scales of progression can be well traced, i. e., the change from the elementary or physical into the mineral, from the mineral into the vegetable, and from the vegetable into the animal. The process of develop- ment is physical; the result is a vital force. Alcohol is the offspring of vegetable decomposition, produced by a physical process of disintegration, of caloric, and moisture Avith hydrogen. The purpbse for Avhich these stimulating agencies are used is to invigorate the activity of the vaso-motor nerves, and thus circulation ; these agents are to be used Avith care, and only Avhen nature becomes enfeebled either by sickness, age, or exposure, and exhaustiAre labor. They are useful in adynaemia, in dyspepsia, and in scrofula, as nutritive and vivifying agents; they are truly restorative of force, physico-vital. The excess or abuse of these stimulants produce morbid conditions of the stomach, liver, kidneys, and brain; and there are many medical substances Avhich Avould produce structural diseases of the organs, in much less quantity and time than liquors, and yet they are considered inert. EAren some articles of diet, were thev so much indulged in, Avould produce some morbid effects upon the system. 62 PROGRESSIVE MEDICINE. And, therefore, Ave learn that these agents add force to assimilation and nutrition, and so they are necessary to the physician, but only as organizers of an enfeebled recuperative poAver of nature. They exhilarate the imagination by propelling more blood to the brain, and thus give the brain more nutrition. They break up inactivity of the nervous matter, and they quicken action and reaction. The poor sot's brain has often been found to contain a minimum of alcohol, and even the lungs also. The reactive influence of this agent is that of de- pression, emaciation, anaemia, and liquefaction of the fibrinous blood. There are medical agents which in large doses Avould produce similar effects to that of liquor in excessive doses, i. e., cannabis, opium, belladonna, hyoseyamus, ammonia, and stramonia. And for nervous irritability Ave have quinine, nux vom., strychnia, phosphorus, ignatia, and many others. In virtue of the untold beneficial effects of folloAvin"- the laAvs of nature, and thus preserving health, I cannot pass Avithout recommending the profession to study more faithfully the advantages that Ave may derive from employing elementary agencies as the physical found .ition of our structure, which may prove the most logical and truest remedy when the organization is in an abnormal condition. Medical science is not entirely speculative; it has a good deal of the practical, and is attained by unmistak- able knowledge of the phenomena of life and its pro- gression. 1 When Ave adopt strychnia, quinin, phosphorus, capsi- cum etc., Ave use them in cases of irritability or agitation of the cerebrospinal svstem. And these remedies are really capable of producing the same or similar results it given in a normal condition of the system. ARTISANS, MECHANICS, AND LABORERS. 63 ARTISANS, MECHANICS, AND LABORERS. These three classes are only made distinct by reason of the different kind of Avork they perform, and the ar- duous labor required of them. Artisans are the better class. They require taste, skill, intelligence, discrimination, and ingenuity; they must have considerable natural abilities; they must have knoAvledge of the selection of becoming colors, and blending of shades in all those Avorks of Avoolen, silks, and tapestry generally. Their mental faculties are called upon for a higher sphere of action than in the case of mere mechanics. The second class are the carpenters, carriage-makers, cabinet-makers, tailors, shoemakers, blacksmiths, etc. The third class consists of those that perform only manual labor on streets, common roads, and farms; also, as servants, hostlers, millers, drivers, etc. The manufactories employ generally a great many girls and boys of a tender age; and besides working all day at their trades, they go to night schools for instruction. They have no play, no recreation, which is so necessary to young children. This deprivation of the natural ele- ments of groAvth, i. e., air, play, and exercise, puts, as it were, a check upon physical development They consequently grow up physically and intellec- tually feeble, and thus they reach the age of puberty in a deteriorated physical and mental condition. Thev are deprived of that physical exercise, from which their secluded lives compel them to abstain, and which lavs the foundation of many diseases of which thev only too soon become the victims. Their physical development and force are unfavorably affected in early life; their nutrition and growth are thus ffrndunllv suffering from the neglect of the physio- logical law; and their intelligence is stultified by the 64 PROGRESSIVE MEDICINE. Avant of the proper elements of vegetative force and neglected instruction. The men and women fare no better; only, they, hav- ing obtained their groAvth, have an etiological reason for less proneness to physical disorganization. The dusty rooms of the Aveavers; the heated and con- fined air; the moisture from steam; the poisonous ex- halations from materials, paints, and the air infected by many breathing lungs confined in a small space; the attitudes of sitting, bending, or stooping over looms and tables or seAving machines for hours; these and a vari- ety of other causes go far to produce those myriads of invalids and cripples that fill up our hospitals, dispen- saries, and other asylums of charity. The tobacco and cotton factories, Avhere constant dust is floating, and pervading the Avhole atmosphere, invari- ably affect the lungs, stomach, skin, and, at times, the sight. Soap and leather factories emanate effete gases Avhich produce a deterioration of the animal economy; they cause asthenic and anaemic diseases. The match and india-rubber factories are also sources of disorganization of the vital forces through the poison- ous and infected atmosphere, which is continuously im- pregnated Avith mephitic gases. Is it not to be con- sidered a very important question—the happiness, health, and life of thousands of these poor creatures? Should not the medical profession, as the recognized faculty, Avhose dictum is accepted upon all hygienic subjects, present these evils for consideration, and, if possible, abolition, and suggest the means bv which fresh and pure air could be therein introduced? The process of ventilation, heiting, and cleanliness should be the first important object of every humanitarian and sanitarian. It is also a question of economv. Bv taking the proper cautions njrainst these putrid smells, mephitic gases, and devitalizing animal exhalations, thousands of ARTISANS, .MECHANICS, AND LABORERS. 65 victims Avould be saved, and the sanitary bills Avould fall to one half of Avhat they are uoav. The diseases Avhich originate from such sources are generally of a malignant and infectious nature. They cause diphtheria, dysentery, hepatic disease, cholera, typhoid fevers, consumption, adenitis, scrofula, eruptive diseases, carbuncles, suppression of the menses, apep- sia, renal diseases, abscesses, and, finally, disarrange- ment of all the organic functions. Dissolution or per- version of the great phenomena of life must sooner or later take place in the majority of cases; hence caco- plastic formations, lymphatic diseases, mal-assimilation, cancer, atrophy, and finally and conclusively, adynaemia. And, furthermore, the surroundings of these estab- lishments are anything but salubrious: Loav grounds Avith stagnant Avater; Avater-closets near, and unclean; animals—like cows, pigs, and horses—and their dung- hills, are generally in the immediate neighborhood. The people avIio live near these factories build shanties, and are poor, unclean, and ignorant; they throAv the slops before their dAvellings, and the Avater they drink is full of animalculi. It is, indeed, from these unhealthy localities that effete poisons arise and infect the rest of the tOAvn or city. There are large numbers of poor girls Avhose emaci- ated countenances, Aveak frames, dejected looks, are Ha-- ing specimens of this barbarous and inexcusable neglect. Their diet is oftentimes faulty and unhealthy, both in quality and the Avay the food is prepared. At this day the question of sustenance has become a serious one, and has called to it the attention of all the Christian and civilized governments of the Avorld. The groAvth of population and the requirements of an enlightened age have brought to civilization an increase of mnnv necessities, Avhich in the orimitive condition of man Avere not even knoAvn. 66 PROGRESSIVE MEDICINE. Naturally, man in his savage state has feAV cares and less necessities of life, and none of those appendages that Aveigh so heavily upon many of us, which are called social duties and requirements. Political economy has become one of the most useful branches of our system of government: it is indeed the basis of national prosperity and greatness. To ensure remunerate labor to the loAver classes, so that they may get sufficient means for subsistence, and thus keeping them from idleness and debasing vices, is truly a herculean and noble task, Avorthy of the most patient and generous of governments. A neglect of this high duty on the part of those on Avhom divulges the affairs of a nation brings about disorganizations, con- spiracies, revolutions, and misery over the land. An honest simplicity of life and living is conducive to health and happiness, Avhereas the corrupting and de- bilitating indulgence of extravagance and vice carries Avith it poverty, soitoav, and desolation. Undoubtedly a simple, good, healthful food ensures physical and mental force, and renders us more capable of enduring the vicissitudes of life. Poor diet, cold, dampness, and mephitic gases, Avith insufficient clothing and unhealthy habitations, Avill produce suffering, dis- ease, and premature decay to a frightful extent. Good clothing is an imperative necessity, and must be suitable to the climate in which Ave live, both in texture and style. This subject calls our attention particularly to the style of dress which fashion imposes upon our Avomen. Indeed, fashion, although commendable as a source of employment, proves often a very foolish and injurious institution, often inconsistent with common sense, ugly, uncomfortable, and extravagant. What is more pernicious than a tight-Avaisfed and low- necked dress, and with short sleeves? What is more absurd and injurious than thin and high-heeled boots? HYGIENE AND DIET. 67 And, again, the weight of most of this paraphernalia is confined to the Avaist instead of the shoulders. Is it any Avonder that there are so many diseases of the uterus? The trouble lies in consulting beauty and taste, instead of comfort and health. From tight-lacing and heavy clothing are derived derangement of diges- tion, hepatic engorgements, painful menstruations, sick headaches, and nervous irritability in the form of in- somnia, apepsia, and hysteria. Physicians, as the proper guardians of the public health, should not neglect to call the attention of parents to these great abuses and wants of the first principles of health. HYGIENE AND DIET. Having pointed out a fcAV valuable causes Avhich produce much suffering and sickness, Ave have hoav reached the preliminaries of demonstrating the remedy. Unquestionably, at the present day the majority of people understand the evil consequences of an impure atmosphere. The paludal countries are constantly giving us evi- dences of their poisonous effluvia; the intensity of an Indian temperature proves the deleterious effect of a tropical climate; the humid atmosphere of England has shown its deAatalizing influence by the absorption of too much animal heat, favoring scrofula, rheumatism, and consumption. The exhalations of the rice-fields of the Carolinas and Italy, and the valley of the Danube, are pestilential in their nature, and fever and zymotic diseases of all kinds are disseminated at the cost of thousands of lives. AcknoAvledging at once that the rice-fields are neces- sities to the human family,as likeAvise are the manufac- tories, yet, Avith all this, there is no reason why Ave should not endeavor to diminish the evils proceeding from human necessities. 68 PROGRESSIVE MEDICINE. Rooms crowded Avith children, or men and AA^omen, should be forbidden. Sehoolhouses should be built in accordance Avith the most approved laAvs. of hygiene, and so should factories and all institutions where a large assembly of people is expected to gather. By exercising energy, patience, and Avill, the authori- ties of our cities Avould soon yield to reasonable plans for improving the health of all. The millionaire, Avhose sole ambition is to leave his name as a perennial memory to the Avorld, can do so only by doing the greatest amount of good. He is the only true benefactor, avIio has in his poAver to relieve suffer- ing and raise the IoavIv. Much evil is due to negligence, but much is also due to poverty and ignorance; and, Avorse than all, many of our incorporated institutions, Avhose sole object is to get the largest percentage upon their capital, building badly constructed dAvellings and large places of business, in order to save a few thousands, by their avaricious- ness are sending hundreds of A-ictims to a premature grave. The appalling epidemics of yellow fever, cholera, small-pox, diphtheria, dysentery, typhoid fevers, etc., Avould become reduced in frequency and virulence. Was it economy to the South to keep the fermenting elements of yelloAV fever ? Is it economy to the East to have the yearly plague? Can it be, in the name of simple common sense, that our municipal governments could be so short-sighted and inhuman as to see nothing and think nothing of the science of hygiene? In ansAver, I regret to say, that much fault lies in the perfect indifference and inactivity of our plrysicians. Would they only take the pains, through the press, to demonstrate the danger and Avickedness of such Avant of the proper means to ensure health they Avould greatly HYGIENE AND DIET. 69 save suffering, and expense too; for sickness is more costly than keeping a Board of Health. Again, that people must be clad according to cli- mates and seasons of the year is an unquestionable human necessity, and at the same time a great and seri- ous expense. The covering of the human body comfortably, taste- fully, and cheaply is one of the greatest causes of happi- ness Avhich Ave may candidly thank civilization and its industries for. There is much or little in our modern discoveries, accordingly as we understand their proper use. Great is the Avaste of food and of clothing, and our people are truly improvident and Avasteful. This is the impor- tant part of economy, of usefulness, and of comfort. Many people cannot be comfortable, for the simple reason that they do not knoAv hoAV to be comfortable. Others suffer from Avants, even Avith the material in their houses, just because they do not knoAv hoAV to make things meet for the desired purposes. I advocate that all our public schools, high or low, should have a cookery and a seAving department, so that every young Avoman leaving the school should go Avith at least the most important knowledge of hoAV to keep house and prepare her food, and hoAV clothing should be made in order to save Avaste and to make it suitable for the purpose intended. Leave the piano, the Greek, and the Latin to those whose fortunes are amply sufficient to let them proceed with these intellectual pursuits, but teach poor girls the practical things of life. The feeble and nervous should always dress warmly. The plethoric and lymphatic do Avell Avith less clothing. And when these rules are not observed by either, both will surely suffer. The fat and strong would prob- ably suffer from too much clothing, as the weak and delicate would from too little. One more thing is absolutely necessary to be not only 70 PROGRESSIVE MEDICINE. mentioned, but insisted upon by all physicians, i. e., cleanliness of dress and of person. Nothing is ino.e conducive to health than simple, Avell-cooked food and good bathing. To insure a perfect immunity from loathsome and epi- demic diseases, the great cardinal conditions should be obserA^ed: 1. Good, healthful food; 2. Convenient and sufficient clothing; 3. Cleanliness; 4. Healthful dAvell- ings, Avith proper ventilation and heating apparatuses. We cannot verify the old adage, "a sound mind in a sound body," without following the first rules of health. Many home-spun articles are far superior in durability and warmth to those made by manufactories. Fashion and fineries should be more disregarded than they are by our working people; for good, well-fitting dresses are not ahvays a la mode, nor is it desirable that they should be so. The shoes should be heavy and strong; rejecting the miserable imitation of " the Yankee make," as they are made of poor material and still poorer shape. One pair of English manufactured shoes will last as long as three pair of the " Yankee make "; therefore the heavy home-made shoe is the cheapest and the best. The love of extravagance in luxuries generally is an American failing; this causes often domestic dissensions and unhappiness. The phrase is true, if not comely: In our prosperity we often forget the rainy days that are to come. We are apt to think of the present alone, and let the future take care of itself. The enfeebling evidences of extravagance and fast living are visible in the delicate constitutions of the present generation. Children often suffer for the fol- lies of their forefathers. Work and plenty go well together; as idleness and miserable poverty are unavoidably linked to one another. HYGIENE AND DIET. 71 Remunerative Avages is only what is due to honest, good labor; just as exorbitant demands for Avork is an evil which does not enrich the poor, but makes them extravagant and vicious. Small remuneration Avith continuous and secured em- ployment is far more desirable than spasmodic high prices, Avhich soon terminate either in bankruptcy to the employer or discharge of the employed. Poverty is not an unnatural thing with us all; it has often its reAvard in sobriety, industry, and happiness. Wealth leads too often to extravagance, frivolities, loss of health and morals, Avith nothing but unhappiness as the off- spring of it all. Food must be fresh, simple, and Avell cooked. Health- ful diet is not only a source of enjoyment, but of nutri- tion and physical force. It is a great gift, that of knoAving hoAV to live. All nations err to some extent as to the proper articles of diet. The English and Germans are apt to adopt too heavy a diet and to eat too frequently. The Latin races, Italians, French, Spanish, etc., live on lighter diet than the Saxon race. This is done in con- sideration of Avarmer climates, and hence more salubri- ous. I believe they use too much vegetable and succu- lent articles and an insufficiency of nitrogenous animal food. Their meats are mostly boiled, Avhile were they broiled they Avould be more nutritious. But of the many errors committed by national fancies and customs in the mode of living, I believe the Americans excel them all. The principal error in the American diet is the in- dispensable pastry in all shapes and kinds. Again, there is the abuse of using hot breads, and SAveetened fruits called jellies, and upon this the children feast. Coffee or tea ad libitum is taken Avith the heaviest meat diet, rendering digestion more difficult and laborious. 72 PROGRESSIVE MEDICINE. The fried meats and vegetables are always to be found on every American artisan, mechanic, or laborer's table —an indigestible and non-nutritious Avay of cooking. And it is not surprising that gastric troubles arise, and that the chylification is imperfect, bringing on mal-nu- trition— emaciation, hepatic complications, nervous disorders, portal congestion, hemorrhoids, constipation, disturbance of the menstrual period, melancholy, head- aches, and dyspepsia in a chronic and complicated kind is the result. Gastralgia, enteralgia, cardialgia, and neuralgia are oftentimes the products of a poorly selected diet; these prepare the Avay to more serious constitutional derange- ments. We have seen before Iioav simply the phenom- enon of organization springs from fermentation and a feAV agencies to favor its development. It Avould, perhaps, suggest that Avere Ave to study better the processes of nature, Ave Avould still more understand its simplicity and its requirements. The fundamental law is constantly before us—good simple food, plainly and Avell prepared: this is all. These are conclusions Avhich I have arrived at through experience and practical observations. Affluence and rich, luxurious living, late hours, and indolence, on the one hand, and poverty, want of cleanliness, thirst, badly prepared food, etc., on the other, will, sooner or later, cause physical and physiological disarrangements leading to final disorganization. Invariably any departure from what is purely neces- sary to the equilibrium of the animal economy causes disorder and disintegration. Therefore, the remedy which Ave can logically recommend is frugality, Avork, good clothing, good air, and good food. DISEASES ARISING FROM IMPERFECT NUTRITION. It is Avell known to the profession generally that there are many diseases Avhose origin proceeds from mal- DISEASES FROM IMPERFECT NUTRITION. 73 assimilation and innutrition, and these occupy a large space in the medical literature, Avhether they present themselves directly or not, organically or functionally, b}7 inheritance or acquirement. The diseases of the digestive organs should always be looked upon with even more apprehension and care than they really are. Such ailments are often dismissed with slight notice and little thought. It is true that oftentimes these very much abused organs are only temporarily and superficially affected ; yet these ailments, slight as they often seem, bring about, in the course of time, a feebleness and a proneness to dis- orders—these slight deviations from piudence in diet are too often neglected and made light of, Avhen, after a feAv recurrences, the indisposition changes to a recur- ring disease. The complications, the symptoms, and the degrees of these anormalities are so numerous that it Avould be an impossibility to enumerate them in any short or uniform classification. Some people by sympathy and reflex action suffer Avith sick headaches, some with a complication of the biliary organ, others Avith eruptions, coughs, and nervous diseases of all kinds and shades. They are often the origin of many physical and vital complaints, and if allowed to po on, they disorganize the animal economy, thus gradually preparing the Avay to some insidious, perverted physical or organic metamor- phosis. Some of the principal and incipient symptoms of im- perfect nutrition are the following: The complexion changes from a clear and health- ful color into a pale yellowish or greenish hue; the activity and vivacity of the person changes into a lassi- tude, Ioav spirits, sadness, or irritability; strength changes into weakness, sleep into insomnia. It affects the mind and intellectual faculties. A sensible per- son is often changed into a peevish, notional, and ir- 74 PROGRESSIVE MEDICINE. rational individual, easily offended and fond of fault- finding. Suspicion arises where perfect confidence existed, and morbid desire for things which were never thought of beforehand if at all, Avere looked upon as absurdities. Women are prone to hysteria and sterility. Hypochon- dria generally affects the male. They suffer with pal- pitation, gastralgia, and enteralgia. The appetite is at times increased and at times destroyed. They complain of sour, bitter taste, eructations, of flatulency, malaise, and constipation. Leucorrhea, ir- regular menses, hemorrhoids, dysmenorrhea, ovaralgia in AATomen. Oftentimes, the ganglionic and splanchnic system of nerves, and even the v-aso-motor, are so af- fected that the correlation of functions is partially suppressed. The process of injestion and ejestion be- comes sIoav and sluggish, from engorgement of the ex- cement system. The great centre of nerves, the focus of vital force, soon becomes sympathetically disturbed, circulation becomes likeAvise impaired, and the blood loses its fibrinous element, becoming liquid by the increase of serum. Complications of the lymphatics naturally folioav. The gastro enteric juices become weak and changed in their constituents. The salivary glands and the fol- licles of the stomach may become morbidly affected, thus changing the process of digestion. These disorders change according to diathesis and idiosyncrasies of sex, age, temperament, occupation, cli- mate, and food. We also find cases of digestive troubles caused by miasmatic effluvia, or brought about by ani- mal or vegetable mephitic gases. CLINICAL, CASE I. Physiodl Examination,—On auscultation I found his lungs perfectly sound. The heart's functions were ir- regular, although its structure Avas free from disease. DISEASES FROM IMPERFECT NUTRITION. 75 I found the liver, on percussion and palpation, to be tender; no enlargement Avas apparent either to the touch or eye. Kidneys Avere healthy, although the urine had a specific gravity of 1030 (phosphates). Semiology.—A young man, tAventy-seven years old, of a nervous, bilious temperament. Complained of some trouble, Avhich he could not Avell describe. He had been a good liver. He slept badly and was restless and un- comfortable ; he had frightful dreams, aAvakening con- fused and not knowing Avhere he Avas. He arose in the morning Aveak and tired. His energy of mind and agil- ity of body had left him. He had no desire for either physical or mental Avork. He complained of having pain in the cerebrum, Avith a feeling of pressure and heaviness. He had lost all desire for pleasure or mirth. He avoided society, and even friends. The table had lost its charms for him, he had no desire for food. His mouth Avas parched and slimy and raised mucus from the stomach. He used stimulants, under the impression that they Avould produce a change. His physician suggested tonics, Avhich meant stimulants in a different form. After a feAv months of this kind of uncertainty, and his bitters (as he called his medicine) not having ansAvered the purpose, he considered himself in a rather critical condition. To be sure, the treatment at the very first sight Avas unmistakably improper, and the diagnosis incor- rect. His skin Avas dry and impervious to a great degree; no Avonder that the urine Avas charged with phosphate of ammonia, and its specific gravity 1030. The excre- mentitious matter was charged with carbonic gas. The stomach was not disturbed with any ferment of acidity, but the intestinal canal Avas. Air accumulated at the ilio-caecal region, ascending upAvard through the colon. This is the ilio-caecal dyspepsia of Dr. Cham- 76 PROGRESSIVE MEDICINE. bers, he having localized the disease on the principle of morbid anatomy. He Avas very despondent and neglected his business. He suffered Avith cold feet and hands, although hot flushes Avould sometimes take the place of chilliness. His pulse Avas Aveak, and regular but frequent. Eyes dull, movements slow, tongue coated, Avhite at the root and reddish on the edges, and breath offensive. His abdomen was inflated Avith gas, memory uncertain, and unable to collect his thoughts. This great variety of symptoms has nothing decided pathognomonic, and would be tiresome and uninteresting to the empiri- cist; but yet they are indicative of constitutional trouble someAvhere in the digestive organs, and it is the duty of the physician to find the organ, or the functional lesion of the chylopoietic viscera. He Avas an inveterate pipe smoker, and a tea and coffee drinker. He chewed tobacco when he did not smoke. Ate hot bread and pastry and retired late. Danced immoder- ately and drank cold drinks when in full perspiration, thus changing the temperature of the stomach and in- testines perhaps ten to twenty degrees in a few minutes. What could or would we think of throwing ice-water on a hot boiler ? But the young man thought himself evi- dently stronger than red-hot iron. This is a very sugges- tive" discovery, which leads us on to the stomach as the organ greatly abused. Etiology.—Looking over the principal objective and subjective symptoms, we find, 1. Indulgence in the good things of the table; 2. Use of cold drinks Avhile his Whole system Avas at a high temperature, causing decided mischief; 3. Late hours and late eating; 4. Smokin^ an old pipe and chewing tobacco. These were the true and. evident causes Avhich brought upon him disarrangement of the digestive DISEASES FROM IMPERFECT NUTRITION. 77 functions, besides a natural predisposition to nervo- bilious trouble. There Avere no real organic pathognomonic symptoms characterizing the disease, but, as it has been said al- ready, there Avere unmistakable signs of derangement of the digestive organs. It Avas a case of inertia, caused by overstimulation, by indulgence and carelessness in food and drink, with the prostrating influence of tobacco. This condition of things deprived the system of much vitality; and the absorbents became sluggish and inactiA-e and the juices Aveak and Avanting in the proper elements of nutrition. The results Avere mal-assimilation, mal-nutrition, and inanition. Although the symptoms Avere not as pronounced as those of dyspepsia, the indications Avere strongly that Avay. I believe it Avas a case Avhich could be called, Avith sufficient good ground, enteric dyspepsia. General Remarks.—Here, in these very cases, Ave must proceed cautiously and patiently, for nothing Avould be gained by heroic treatment. These are generally dis- orders of a chronic nature, trying the patience of both patient and physician. But Iioav could it be otherAvise? These symptoms have been groAving gradually upon the system, and, therefore, have become implanted there, and their returning to a normal condition requires the same sIoav process of re-invigoration. And it is clear, that Ave must base our mode of procedure upon the princi- ples of organizing and Aritalizing the proteine com- pounds. This patient not only disregarded many of the impor- tant requisites necessary to insure health and comfort, but deliberately took opportunities of disarranging the cliemico-physiological process of digestion, and thus brought about a physico-vital disarrangement of the whole system. It Avas not a case Avhere regulated diet alone Avas 78 PROGRESSIVE MEDICINE. sufficient to bring about a change. It certainly re- quired immediate advice on the most important laAvs guiding the primary principles of organization, namely, 1. Rest of the digestive organs; and, 2. A strictly regu- lated diet on sound physiological regulations. There Avas evidently a loss of correlative, digestive functions. This prolonged loss of organic force could not be regained, except by a patient, continuous, and logical treatment, based on physiological principles, aided by medical advice. This gastric disorder had brought about a general systemic trouble, Avhich required con- stitutional treatment. Through the neglect of proper medical treatment, and the process of over-stimulation, much difficulty was put in the Avay of a speedy recovery. The " regular doctor " had evidently put fuel to the fire; he stimulated Avith quinia, stiychia, and liquor; he irritated by acrid bitter agents, i. e., cathartics, etc. From this mode of irrational treatment, debility and inanition was slowly disorganizing every physiological function in the economy. Tnis case presented a feebleness or asthenia from over-stimulation and abuse in diet; and nothing but injury could be expected from stimulants and cathartics. It is but practical common sense that Ave should re- ject an agency Avhicli will create mischief and increase the disease: it is pure logic that would suggest other plans than those Avhich had been used, more in conform- ity Avith the science of physiology. Medical Treatment.—Having considered the case as one of asthenia, accompanied by adynaemia from mal- assimilation and nutrition, Ave are, therefore, prima facie, to accept it as one of nervous exhaustion, or Avant of physico-vital force; and from this standpoint we must proceed by invigorating the phvsical phenomena of nutrition and life. The mal-assimilation of the nu- tritive elements Avas due to the disordered condition of DISEASES FROM IMPERFECT NUTRITION. 79 the organism produced by hyper-nutrition and the rest of the evils already pointed out. Were, therefore, medi- caments alone sufficient to add physico-vital force? The constituents of the proteinaceous compounds are not changed or increased by drugs. The histogenetic pro- cess is not increased or returned to its normal condition by medicaments. Nutrition and life are not considered to be found in chemicals or drugs. Rut diseases can be diminished, and even cured, by proper medication, provided it is assisted by the vital- izing principles of nutrition ; but those principles are not obtained by food alone, but also by the employment of those physical principles of which the animal economy is in a great measure the recipient, and from Avhich many constituents are continually received and others organ- ized. And Avith these preliminaries Ave surely can enter the arena of medical science Avith a fair chance of doing justice to our responsibilities. In this case I used remedies Avhich are Avell known as organizers of physical force, i. e., nitro-hydrochloric acid, phosphate of soda, phosphate of magnesia, kali sulphatis, nux vomica, pulsatilla, bryonia alba, arsenicum, aloes, ferrum peroxidum, or phosphatis pepsine, lycopodium, and capsicum an. These remedies Avere given at differ- ent times, changing from .the mineral to the vegetable medical agents. The strength Avas generally that of 3-10, although I have given the iron in larger doses, i. e., five to fifteen drops four times a day. Hygiene and Diet.—-The physical principles are— motion, air, light, heat, bathing (Avater), electricity, early hours, and plenty of oxygen. The diet Avas composed mostly of nitrogenous ele- ments. Light soup, mutton, beef, chicken, and fish. These ingredients should be so cooked as to retain their nutritious constituents. The vegetables Avere rice, peas, beans, barley, sago, and tapioca—rejecting potatoes, pastry, coffee, tea, rich 80 PROGRESSIVE MEDICINE. and carbonaceous food generally. He could not derive benefit from stimulating liquids, for he had already ex- hausted their utilit}\ The liquids Avere cream, milk, cocoa, pure Avater, and, at times, some good claret at dinner. These articles were to be taken in small quantities at first, increasing as the power of chylification increased. In all these complicated cases the diathesis and idiosyncrasies of the patient must hi taken into consideration. Where there are lymphatic engorgements and tumefactions Ave haAre to use specific agents for that system, e. g., belladonna aurum, mercurius, iodidi-iodine, barita-muriatica, kali broinidi et chloricum, mineral baths, etc. Symptomology alone Avould not go fir enough, but Ave must select those remedies that, besides having a simi- larity of symptoms, haA^e also similar pathogenetic effects and lesions. To this suggestion I Iciioav many physicians may object on theoretical grounds, but not on practical experience. We, syinptomologically speak- ing, might treat headache, pain in the stomach and back, irritability, apepsia, and insomnia Avithout looking deeper into the cause of these symptoms; then Ave Avould be no better than empirics ourselves. Pathology, etiology, and semiology form the grand field of inquiry, Avithout Avhich no sound diagnosis, and still less the prognosis of the case can be satisfactorily made out. The success of the treatment of all diseases, in my opinion, depends upon the thorough knoAvledge of these factors. CLINICAL CASE II. Physical Examination.—A young Avoman of four and tAventy years of age, of a nervo-lymphatic temperament and excitable idiosyncrasies. Lungs sound; heart's ac- tion irregular, but organically sound; kidneys and liver normal. Semiology.—She came to me some four years a«-o She complained of general malaise and distress, feeble- DISEASES FROM IMPERFECT NUTRITION. 81 ness, constipation, headache, flatulency; sometimes looseness of the bowels, mental depression, painful men- struation, desire to lie down, slept badly, urine greatly increased in quantity, Avith an unnatural Avhiteness and specific gravity only 1000-10; hemorrhoids, pain in the back, flushes of heat and cold alternating, cough, and rumbling in the intestines. She Avas nervous and Aveak; the slightest noise or domestic disarrangement annoyed her, and she Avept easily; she feared that some malignant disease Avas groAving upon her; she aAvoke in the morning unrested and chilly; she looked pale and haggard, anxious and excited; appetite normal, but felt depressed after eat- . ing, and a heavy Aveight distressed her stomach; flatu- lency and eructations relieved her. The colicky pains Avere confined to the small intes- tines, Avith sympathetic nausea and vomiting; unpleas- ant burning at the stomach Avith expectoration of mu- cous fluid; mouth and tongue Avhite and slimy; cardiac irregularity, due to nervous Aveakness, approaching as- thenia; hepatic torpidity, leucorrhcea, yet the uterus Avas perfectly healthy; dyspnea was, at times, very distressing to her; yet her lungs Avere sound and the heart Avas only functionally irregular. These organic troubles, as far as I could fathom them, were simply the result of reflex influences. Her mother confessed that her daughter was fond of candies, pies, coffee and tea, and had been allowed to indulge in them ever since she Avas a child. She Avas a very diligent student when she went to school, and perhaps had her brain packed with all sorts of scientific branches, weakening her intellect, probably, more than doing her any practical good. She studied late at night, and often had a good lunch of cake and pie before going to bed, in consequence of which she awoke in the morning complaining of a rest- less night and exhaustion. 82 PROGRESSIVE MEDICINE. The mental faculties w.ere so depressed that I feared mental aberration, in consequence of nervous irritation and anaemia. The sympathetic system was also much involved and hysterical signs Avere prominent. Etiology.—1. On the diagnosis of the case I found mucous irritability of the stomach and its follicles, and aphthous ulceration. In such a physical disorganiza- tion it is easy to imagine an altered gastric juice and peptones. The hypersecretion of the mucous mem- brane of the organ produced inanition and nervous Aveakness, and from such complications arose mal- assimilation and a perverted condition of the vital force (adynaemia). 2. The muscular force and the cliemico-physiological functions Avere in an abnormal state. The animal econ- omy Avas put out of its normal functions to such an ex- tent that emaciation, inanition, and anaemia Avere the results. 3. The mucosity undoubtedly extended to the in- testines, and the process of injestion and ejestion Avas retarded. This pathological condition of the digestive organs threatened to form cacoplastic neophytes, and to be- come enteric consumption. The process of histogene- sis being in a precarious condition, the lymphatic ves- sels and glands Avere enfeebled and sympathetically affected. The defective proteine organization must, by necessity, in time, have brought about plastic changes—hence tumors, cancers, ulcerations, and hetero lymphoma or atrophia lymphatica, and consumption scrofulosa Avould havTe been the result, and might have taken place in the mesenteric glands. The drain of a large amount of secretion must Aveaken the whole process of repair, as Avell as imprudence in eating—pork, pies, and hot bread. DISEASES FROM IMPERFECT NUTRITION. 83 Hygiene.—Motion by Avalking every day, or driving, any action producing heat, together Avith the air and light, rendered assimilation more probable. In ad- dition to the above, I ordered sheets for packing her Avhole body, so as to equalize circulation and diminish the hyperemia of the abdominal regions. Early hours for retiring and rising, although I required a frequent recumbent position, so as to rest the internal organs. Gentle occupation, so as to relieve the mind from dwel- ling upon the disease, and cheerful company for an hour or tAvo at a time, for anything Avould have tired her be- yond description if not used Avith great moderation. Dietetics.—The necessity to understand Avell the prop- erties that Avill build up the physical force and func- tions is so imperative that I cannot dAvell upon it too much. It noAv devolves upon a physician to secure the best means to re-establish the recuperative power of nature in the best and most rational manner. As I have said before, these cases have their origin from the very fountain of life, and from that very basis only can we expect to cure them. I have dAvelt at length upon the necessity of knoAving exactly Avhat are the elements Avanted and Avhat are the functions impaired, for it is only then that Ave can sug- gest a treatment Avhich might be expected to be at all beneficial. Oxygen, motion, heat, bathing, rubbing, and proper dietetics may be the necessary means to re- cuperate the physical force. One patient needs rest, another activity. One needs oxygen, another heat and carbon. One nitrogeuized food, another albuminous or amylaceous. One needs acids, another alkaline. One metalloids, another mineral metalloids. In this lies the whole process of physical laAvs and medical success. At breakfast, cocoa with cream, or the yolk of an egg- beaten in white sugar, Avith the addition of Avater and a little wine. In this she had dry buscuit—nothing more. 84 PROGRESSIVE MEDICINE. At dinner, beef-tea, or clam-broth, Avith bread and no butter. In the morning a small quantity of boiled hominy Avith cream, and at noon rice or hominy. Sup- per—clam-broth, plain rice-pudding Avithout eggs in it, sago Avithout eggs, and black tea Avith milk in it. This diet was increased in quantity and someAvhat varied; but I abolished potatoes, all pastry, and all sorts of stews and fried things. At times I allowed half a cup of strong coffee, with cream, as an iuvigor- ator and nutritious element. Medical Treatment.—Dr. Chambers says: " Practi- tioners of the Homeopathic laAV fail sadly in the treat- ment of enteric diseases, because the remedies do not act promptly and are not given intelligently, but only symptomatically, taking no notice of the pathological condition of the system ; hence a long and unsuccessful treatment." And he unbecomingly boasts of having cured a myriad of cases coming from practitioners of the Homeopathic school. I do not doubt his Avord, but discrimination should be exercised as to the standing of those practitioners. Unfortunately, there are many of the so-called Homeopaths Avho are not physicians in the full extent of the Avord; and there are many so-called rational school men Avho are anything but rational in their treatment of diseases. My impression is that Dr.Chambers could not assign on Avhat principle he himself practices. He adopts reme- dies that have certain pathogenetic effects, and most of them act, I dare say, Avith all due respect to him, on the law of similarity. Drs. Chambers and Pavy have Avrit- ten Avell upon the diseases of the digestive organs, but both have come short of the mark. I could make long criticisms, but my aim is not to fight other men's ideas as much as to adopt what is good in them and forget the rest. My practical experience with diseases of this nature leads me to state frankly, and Avithout any sectarian DISEASES FROM IMPERFECT NUTRITION. 85 feeling, that a remedy which has acquired a dynamic force has also acquired atomic force and molecular affinity for the malady in question, provided that the remedy is rightly selected: by that Ave mean, patho- genetically, in large doses; and, dynamically, Avhen prepared for medical treatment and morbid diseases. There are only a feAv exceptions to this rule, and they are so feAv, indeed, that they come under the head of anomalies rather than of medical diseases, and are either toxic poisons, like chemicals, or malarious from alluvial soil, or indigestibles in the stomach, Avhich require ejection by an emetic. Faecal obstruc- tions may require a good lubricating agent, like oleum ricinis. But these are more mechanical agencies than therapeutics. Again, the question is not of doses, for that matter is entirely experimental in both schools, ac- cording to the diathesis and idiosyncrasies of the pa- tient^ the climate, the seasons, and the type of the malady. Such good authority as Dr. Chambers ought to knoAv Avhat Professor Prout said about blue mass: " It is a most useful remedy in certain hepatic diseases, but like dram-drinking, if often used, must be in- creased, and leads to o\*cr-action and into debility of the liver, which is the focus of its action." Does not every Avell-informed physician knoAv this, that blue mass is capable of producing a disease for Avhich it is given by the rational school? Do not podophyllum, blue mass, aloes, strychnia, rhei, and many others, produce effects upon the stomach and intestinal canal, liver, and the absorbents similar to those for Avhich they are pre- scribed? Do not quinia and belladonna, phosphorus and arsenic, bismuthand nutrum muriaticum affect the mucous follicles, the ganglionic system, and lymphatics or absorbents similarly as the disease they are given for? But there is no desire on my part to convince Dr. Chambers of the fallacy of his statements Avhen he runs down " siniilia." It is enough that he does a Avrong to 86 PROGRESSIVE MEDICINE. science; and true scientific men should be above sec- tarianism. It Avould not take much trouble to shoAV the similarity of mercurial irritation to pyrosis and gastro-hepatic and gastro-intestinal disturbance. Ipecac and strychnia are Avell-knoAvn remedies to act upon the spinal plexus of the nerves, and through them affect the ganglionic. We could go on ad libitum, getting the physiological effects from a pathogenetic basis. The pathogenesis of acids and their chemical action demonstrate at sight Avhere and how they should be used according to the laAv of similarity. And again, the action of the metal- loids and metallic alkaloids upon the absorbents and lym- phatics is Avell known. Give an alkaline Avater to people that do not need that agent, and Avhat Avould be the con- sequence? Dr Chambers could ansAver us too Avell. Dr. Chambers speaks of capillary congestion as a cause of pain in the pyloric region, and suggests a process of blistering and bleeding. Hyperaemia is recognized b}T thirst, quick pulse, and pain, but certainly the doctor has not forgotten the beautiful blush color made by the capillary ramifications of the stomach, and that condi- tion is often produced by a sthenic disease and not by a simple phlogosis. What then? Is the hyperaemia from nervous influence produced by irritability to be treated as phlogosis per se? Surely, depleting has a temporary influence, and Avill even relieve neuralgia, but this superficial and temporary relief has no curative poAver. Our remedies, given according to the laAv of similar- ity, proceed from the pathogenetic effects of the same upon any given point, and they are truly specifics Avhen Avell chosen. 1$. Ipecac, 3-dec. grs. xxx. M. et devid. chart, xx. Dose—One poAvder every three hours. DISEASES FROM IMPERFECT NUTRITION. 87 An improvement Avas decidedly taking place. I used the remedy for five days. I gave her two days rest, and then gave— #. Antim. crudum, 3-dec. grs. xxx. M. et devid. chart, xx. She used the medicine for fiATe days, and then came to see me. I perceived an improvement, as the mucous discharge had diminished and the pain had left her. But there Avas something more left, viz., hepatic trouble. #. Iris florentina, 3-dec. gutt. xvi. Aqua distill., f ii. j)ose—One teaspoonful every three hours. On the fourth day she came and told me she Avas better every Avav. Her boAvels had moved quite regularly, and the color of the faeces AA^as more natural. Food did not distress her, and her general appearance was better. I prescribed $. Mercurius alkaliz. 3-dec. grs. xvi. M. et devid. chart, xvi. #. Belladonna, 3-dec. gutt. xvi. Aqua font: ? iisj. Dose—One powder alternately every two hours with- a teaspoonful of the liquid. The medicine lasted ten days, and during that time she observed the dietetic and hygienic treatment already mentioned, Avith cold applications upon the stomach and boAvels. I concluded by giving her liquor-potass arsenicalis, five drops in ten teaspoonfuls of Avater, and of this, one teaspoonful every four hours. After two months of treatment she left me apparently well, although she Avill never be a strong Avoman. CLINICAL CASE III. A young girl, seventeen years old, came to me in 1870, for treatment of a chronic dyspepsia. She Avas dejected 88 PROGRESSIVE MEDICINE. and had lost nearly all hope of recovery, from having received no benefit from the dominant school of allo- pathy. Physical Examination.—On auscultation I found the rhythmical action of the heart to be greatly disarranged. The pulsations Avere irregular and quick, Avith a small amount of organic force. On palpation I found the epi- gastric regions tender and bloated. The liver Avas en- larged and painful. The abdomen tympanitic, and boAvels Avere constipated. She suffered at times Avith dyspnea, although the lungs Avere sound. Kidneys Avere irritable, and the urine Avas Avhite and too light in specific gravity. Skin dry and impervious. Uterus fee- ble of action Avith scanty menstruations. Nervous sys- tem appeared entirely in a state of asthenia. She Avas of a nervo-bilio-temperament. Semiology.—She complained of burning at the pyloric region, Avith pain at the base of the larger curArature of the stomach approaching gastralgia. Food distressed her A-ery much; it laid heavily and undigested for some time in the stomach, and had often to be ejected, Avhich Avas generally accompanied Avith a large quantity of mucus: then she felt better. The abundance of mucus undoubtedly prevented the action of the gastric juice and the formation or organization of the peptones, thus the food fermented and became al- most offensive, causing pyrosis and offensive breath. She also complained of a dead feeling in the boAvels, Avhich conveyed the idea of perfect torpidity and Avant of muscular action (parystaltic) of the intestines. The constipation Avas often folloAved by free and diarrhoeatic discharges,Avhich relieved her from that unpleasant sen- sation of fullness, although she felt the effect of pros- tration. She slept badly and got up in the morning unrested. She had no desire for food and felt continually in a state of exhaustion. Her tongue Avas coated Avith a DISEASES FROM IMPERFECT NUTRITION. 89 slimy Avhite mucosity and Avas trembling and very pale. She avoided society, although so young and pretty, and brooded upon her sad condition. She had spent much time and money and taken gallons of medicines, with perceptible injury to herself. She Avas desponding and suspicious ; had lost confidence in physicians. She Avept frequently, and everything seemed to go, as she expressed it, to her stomach. Her complexion Avas far from clear ; it had a hue of yelloAV tint deep in the skin. The liver Avas unable to go through the physical process of disengaging the biliary elements from the venous blood, hence biliary suppression. Having suffered for five long years, the disease Avas making great headAvay into the economy. The physical and physiological functions had lost vigor and harmony. Their influence upon the absorbents Avas established to an abnormal degree, debility and anaemia Avere disintegrating the very foundation of life. There Avas great mental debility and prostration. She became feeble and indifferent to everything. Hepatic derangement, Avith suppression of biliary secretion. The ductus communis Avas tumefied and engorged with mucus. The lymphatic system Avas normal, except, perhaps, a little hyperaesthesia from sympathy and mal-assimi- lation. Her nervo-bilio temperament predisposed her to bilio-nervous affections. The alkalinity of the secre- tions of the salivary glands (cyanide of potassia) was insufficient, hence lactic acid in excess, and irritability of the stomach. The pneumogastric nerve, radiating from the lungs and heart to the stomach, Avas exces- sively sensitive, and by reflex action caused those complications already enumerated. Every sensation carried a certain influence to the stomach—the focus of the disease. Her morning indisposition sIioavcmI enervation; she Avas therefore unfit for any occupation; but as soon as 90 PROGRESSIVE MEDICINE. she seated herself and commenced her allotted Avork she became faint, preceded by trembling and a cold perspi- ration. And again, pain in her boAvels Avould soon pro- duce a loose evacuation. Etiology.—1. Indulgence in pastry and sweetmeats; 2. Over-study and late hours; 3. Abuse of ATegetable food, and not sufficient nitrogen, producing a physical Aveakness of the chylo-poietic A'iscera; 4. Diminished physical force, and cliemico-physiological functions; 5. Imperfect histogenesis. The over-indulgence in any lacteous and saccharine materials deteriorated her health to such an extent that inanition Avas fast gaining ground. And these unassimi- lated ingredients became fermented, hence flatulency, eructation, and formation of gases in the intestinal canal. • These physical conditions Avere devitalizing and the juices became changed and acidulous. Her nervous system gave signs of asthenia; the blood became im- poverished, hence hallucinations, insomnia from anaemia of the brain. Further, neglect of exercise, air, and bathing increased her physical difficulties. Her style of living in closed rooms, overheated by artificial Avarmth, and her disregard of proper diet, if continued, Avould have soon put an end to her life. It being beyond question that the digestive organs and their juices Avere seriously affected and perATerted, the problem Avas pre- sented to us clearly and forcibly: Can Ave restore the vis-vitae and return to the system that which it has lost during a series of indulgence, neglect, and imprudences causing loss of physical force and normal action. This proposition is not to be lightly ansAvered. The complexity of the case is such that no hasty conclusion should be arrived at before a satisfactory examination of that Avhich is favorable, and that which is not. A cure, radical I mean, cannot be expected short of one to tAVo }rcars. DISEASES FROM IMPERFECT NUTRITION. 91 The re-establishment of a physical equilibrium and vital harmony cannot possibly be accomplished, without commencing the process of repair from the very founda- tion. Evidently the starchy and saccharine materials Avere not easily acted upon by the Aveak gastric juice, and it passed the chyme into the intestines in an unsatisfac- tory or crude condition, there to become chyle. A perfect chyle cannot be elaborated from an imperfect chyme, for the very reason that Ave cannot make good bread out of poor flour or badly prepared yeast. This illustration is a practical Avay of delineating the bound- aries of the two digestions. The Avhole histogenetic process Avas interfered with by this mal-assimilated chylification. The normal emulsion Avas out of the question; it could not be produced or vitalized properly from an acidulous chyme. Hence the proteine com- pound Avas deficient in those elementary principles that constitute perfect nutrition. If Ave have reasoned upon our proposition correctly, the solution, or rather the proceedings necessary, are clear and Avell pointed out for us to act upon. First, proper nitrogenous diet; and the reason is obvious that this nutrient Avas the only one neglected, and that it Avas the only one in Avhich I could expect any vital result. Dietetics.—AlloAved: Eggs, beef-tea, cream, roast-beef rare, mutton, clams, cocoa, peas, lentils, birds and fish. Not alloAved: Potatoes, pork, hot bread or cakes, pastry of any kind. No coffee or tea, but Avine and old ale. Morning meal: Eggs, cocoa, toast, and oatmeal boiled for six hours. Dinner: At first, beef-tea alone, Avith bread and a Avineglassful of Burgundy. After the digestive organs gave sufficient signs of improvement, rare roast beef, or birds. Supper: Cocoa, and a bird, or clams. This is the first stage of the dietetic treatment, and Avas folloAved 92 PROGRESSIVE MEDICINE. by larger quantity and variety; but no amylaceous food or glucose Avas indulged in for a long time. Hygiene.—Bathing every day in tepid, salt Avater. Gentle exercise, as Avalking early in the morning. And even these rules had to be changed according to strength. After a feAv months, I ordered her to go roAving and riding in the country. Medical Treatment.—It Avas imperative that I should use a rational mode of procedure to reinforce the physi- cal functions. I became convinced that the therapeutic success depended upon Avhich special system I selected for operation. The great depression of the central force and all its collateral branches pointed out to me the basis of operation. The emaciation, adynamia, in- anition, and anaemia Avere four points Avhich had to be relieved, supported, and reinforced. If the so-called Rational school ever errs, it errs in the management of these cases, and the brilliancy of its eclectic system of medicine falls far short of the mark. The cathartics and stimulants Avhich Avould have been used here, Avould have had a most destructive and un- scientific effect. Physicians might deny that such a treatment would have been adopted; but, if so, they would not endorse the rules of eliminating the faecal accumulations, disengaging the absorbents by the same process, and then toning them up, like harp-strings, to the normal condition Avith the tonic-stimulant process of quinia, stryeiia, iron, and astringents. I have no desire to find much fault with the other school, but Avhen they assume the title of R itionals they must stand the test and the criticisms. No doubt they employ remedies that, if given in smaller doses and under a different principle, Avould succeed Avell, but heavy doses promiscuously given Avith compounds Avill never give them a compass to steer by, or a point of appui to go to with a reasonable amount of success. A DISEASES FROM IMPERFECT NUTRITION. 93 mariner would be equally at a loss Avere he to folioav the currents that seem to lead him, or the Avinds that swell his canvas, Avithout any surer indications. It is my desire to point to remedies Avhich have a peculiar and specific influence upon the organs of digestion, and leaving out many collateral remedies Avhich frequently might be usefully employed. I treated this case with the folloAving remedies: Bry- onia, quinia, phosphate of magnesia, pulsatilla, igna- tia, natr. phosphoricum, lycopodium, bismuth, ferrum phosph.; kali sulphatis, carbo veg., pepsine, calc. phos- phorica, manganine, etc. Noav Ave can detect easily the relation existing betAveen disease and remedy. It is, in my opinion, the most reasonable acceptation of the law of similia. CLINICAL CASE IV. Mrs H., tAventy-seven years old, and a AvidoAv. She came tome in thespringof 1875, complaining of a chronic dyspepsia. After trying the rational school to her heart's content, Avithout the least benefit, concluded that she Avould try the neAV one. She Avas a country lady and had the benefit of pure air, as the place where she lived Avas healthy. Physical Examination.—Chest small and badly formed (pigeon-breasted). Respiration tAventy-four to the min- ute, with a tendency to cough. No organic disease of the lungs existed. Atrophy of the liver and painful on pressure. BoAvels constipated and felt hard and full. Skin dry, rough, and yellow. Great emaciation. Heart normal, although at times its functions or rhythms Avere disturbed. Kidneys Avere normal, but passed urine fre- quently and devoid of solids. Tongue coated yellow and corrugated. Eructation and flatulency with tormina, and, at times, diarrhoea. Stomach tender on pressure. Face wrinkled and prematurely old. General appearance, that of atrophia lymphatica with a scrofulous diathesis. 94 PROGRESSIVE MEDICINE. Semiology.—I found her in .the most deplorable physi- cal condition. Emaciation, asthenia, inanition, and anaemia. She had been married several years, Avithout issue. She Avas of a lively disposition, but changed into sad- ness and despondency. Her nights Avere passed rest- lessly, her food disagreed Avith her and gaA^e her pain in the stomach. She took no exercise, and had no ac- commodation for ablutions. Her diet Avas composed of the usual kind. Pork, ham, fried eggs and meats, pastry and hot bread, Avith poor tea and coffee. She retired early and arose early. She had more to do than her physical strength could bear, and consequently became often exhausted, and suffered Avith severe headache and pain in the back. The signs Avere those of mal-assimilation and mal-nu- trition, Avith a tendency to heteroplastic formations. The result of deteriorated blood predisposed her to tubercular formations, and the nucleoli of the liver Avere shrunk and almost pervious. The condition Avas alarm- ing in the extreme. The gastro-enteric juices Avere peiwerted to poor chylification, and thus the histogenetic process Avas dis- arranged. The Avhole lymphatic system shoAved atro- phy. The ganglionica and A*asa-motor nerves Avere excessively Aveakened. The only beacon light of this fearful condition Avas a strong A'ital force. Portal engorgement Avith hemorrhoidal tumors. The venous blood Avas impure and leucophemia Avas gaining ground. Suppression of biliary secretion from organic difficulty. The functions of the Avhole organizing pro- cess Avere deficient in physical and organic force. The Avhole process of life and repair AAras so disturbed that chronic cachexiaAATas stamped in her face. SheAvas a sensible woman and retained much mental vigor, and therefore her condition Avas Avell knoAvn to her. Etiology.—1. Scrofulous diathesis; 2. Physically fee- DISEASES FROM IMPERFECT NUTRITION. 95 ble, and particularly the organs of digestion and assimi- lation; 3. Disregard of hygienic rules; 4. Indigestible ingredients of diet. 1 know not of any directly exciting causes. Hygienic Treatment.—I must confess that I Avas at a loss Iioav to commence a treatment, as my prognosis Avas unfavorable. I had no faith in a recuperative force, hence I Avas afraid to use radical agents. HoAvever, I had no alternative, so I ordered a tepid bath Avith a tablespoonful of bicarbonate of potass, so as to act upon the absorbents, every other night. Cold Avater Avas out of question, and the Avarm bath would equalize circulation and temperature. Again, I Avanted to act upon the emunctories of the cutaneous surface, so as to assist the liver and kidneys in removing the effete materials. 1. Rubbing her Avhole person Avith a rough toAvel; and, 2. Walking or riding in the open air during fine weather, morning, noon, and afternoon. If not possible to ride or Avalk, she Avas to Avork in the garden as much as possible. This plan, if Avell considered, often brings about such reaction as to insure success. Motion, atomic heat, light, decomposition, and repair, one and all, move in co-ordination. The nervous force increases, the blood becomes richer, and the equilibrium and harmony is re- established. These elementary principles, blending, as they do, forces and physical laAvs, increase the great phenomena of the vis-vitae and Avith it the secretions and excre- tions. Dietetics.—These nutrients, to be useful, must be Avell chosen and Avell assimilated for the process of organiza- tion and repair. Oxygen is an indispensable element to the metamorphosis of physiological functions. Nutrition cannot take place Avithout combustion and heat, for this brings about functions and forces. The 96 PROGRESSIVE MEDICINE. liver, one of the principal factors of the organization, must be stimulated to perform its organic function, and this can only be done by the least carboniferous and nitrogenous food, and the greatest amount of oxy- gen and pure Avater. And yet the case needed some animalized food; and Iioav to accomplish digestion Avas a difficult question, considering the enfeebled condition of'digestion. I put my patient on cream, which she could get easily in the country, morning and night, with old bread and no butter; beef-tea at dinner, Avith a little brandy, sugar, and Avater. I kept her on these nutrients for tAvo Aveeks. Then, I alloAved her oatmeal, cocoa, and the yolk of an egg; at dinner, mutton chops broiled, Avith bread, and a glass of wine. At supper, clam broth with bread and a cup of black tea. She gained steadily, her color changed from yelloAv to Avhite, her pulse became full and f even, respiration fuller and twenty in a minute. I kept her on the same diet, except Avith a little change in the quantity, and gave her peas, hominy, and rice. Coffee disagreed Avith her. Medical Treatment.—I had very little hope from the therapeutics; but I thought I Avould use those agents Avell knoAvn to support the elementary principles of life. From my knoAvledge of the Rational school, I knoAv that aloes, mercury, rhei, ipecac, quinia, cinchona, and stry- chia had been used ad libitum, and I therefore pre- scribed, JL Natrum phosph., 3-dec. grs. 1. M. et devid. chart, xxv. Dose—One poAvder every four hours. The medicine lasted her a Aveek, and then she came to see me. In addition to this I applied hot fomentations to the liver at night. She returned improved and in good spirits. The diet Avas continued, as she became satisfied with it. I found that her stomach was not quite up to her DISEASES FROM IMPERFECT NUTRITION. 97 general condition, so I ordered: Jfc. Pepsin and hydro- chloric acid, to assist her digestion. Her improvement Avas quite satisfactory, and yet her liver did not act Avell. Ii. Podophylum, 3-dec. grs., xxx. M. et devid. chart, xv. p. Nux vom., 3-dec. gutt. xxx. Aqua distill. f iv. Dose—One poAvder every two hours alternately with a teaspoonful of the liquid. On the fourth Aveek she came back smiling, and had gained in strength and flesh. The baths Avere continued, as Avell as the diet and ex- ercise. I gave her general directions as to her mode of life and the following prescriptions: #. Bismuth subnitr., 1-dec. grs. lx. M. et devid. in chart, xxv. #. Sulphur, 3-dec. grs. lx. M. et devid. chart, xxv. Dose—One bismuth powder every three hours. Next day the sulphur in the same way—alternating the day and the medicine. The Avoman Avas strong in mind, and adhered to the treatment and directions. She left me. The other day, five years after she first came to me, I saw her and she Avas Avell and happy. CLINICAL CASE V. In the year 1869, Avhile I Avas practicing in the Avest- ern states, among the agricultural people, I was called upon by a farmer, Avho Avas above the common average in intelligence and mental culture. He entered my office, and Avithout prelude asked me: " Doctor, Avhat is good for Avorms? Ave are all cursed Avith the devilish things." The question was a droll one, indeed, and surely not easily ansAvered. He stated that for tAvo years he had noticed that his children had Avorms, and 98 PROGRESSIVE MEDICINE. that they greAv pale and thin, and had lost that liveli- ness and mirth so natural to the young. He had given them vermifuge for months, under the guidance of a Rational doctor. It had only a temporary relief, and the parasites soon returned as bad as ever. He Avas satisfied that the strong anthelmintics and the Avorms Avould soon have a deleterious effect upon the patients; so he concluded to see if a physician Avho Avas not of the Rational school could think and act Avith judgment. I laughed at his jokes, but felt the force of them. I took much interest in the case, and told him I could give no ansAver Avithout seeing the children. Semiology.—The children Avere brought to me a feAv days after this remarkable visit. I found them emaci- ated, pale, and listless, with sunken eyes, tumefaction of the abdomen, offensive breath, itching at the anus, and incontinence of urine. They had a cough, voracious appetites, itching of the nose, skin dry and rough, and at night great restlessness, raising themselves from bed in a frightened condition, screaming and grinding the teeth together. At times they Avould Avake up almost choked to death. In the morning they found Avorms craAvling in the bed. They looked anaemic and starved. The mother's constitution Avas of a nervous, irritable character, having the most ungovernable temper; she also suffered from the same disease. They Avere badly clad, and the locality Avas damp and SAvampy; they had bilious, remittent, and intermittent fevers, caused by an endemic, malarious effluvia. These poor creatures had constant looseness of the boAA^els, from irritation caused by these parasites. The father brought me specimens of the Avorms in a bottle. I found them to be about an inch and a half long, Avhite. Avith a sharp pointed head, viz., ascaris ver- micularis, and under the microscope they looked like a shoemaker's bristle. This parasitic disease became DISEASES FROM IMPERFECT NUTRITION. 99 chronic, and produced considerable physical changes from mal-assimilation and inanition. Etiology.—Their main diet was pork, milk, corn meal, pastry badly cooked, bread made of poor flour, and heavy. Ham and succulent and starchy, indigestible articles Avere constantly in use. They lived upon these farinaceous and carbonaceous materials, omitting beef, mutton, fish, eggs, and nitrogenous vegetables. The hygienic laAv Avas at nil, privies, stables, styes for hogs, etc., Avithin a feAv yards of the house. The poisonous and infected air, Avith the Avater thoroughly impregnated Avith the floating molecules of these ex- halations, together Avith the food, Avere the true prox- imate causes. Parasites generally spring from Aveak digestion, mal-nutrition, and fermentations. This Avas their condition. Their diathesis being leuco-phlegmatic predisposed them more readily to the disease. Hygiene and Diet.—The principal object in vieAV Avas to correct the proximate causes; therefore they Avere di- rected to use nitrogenous food (and abolish pork and starchy or succulent vegetables), i. e., beef-tea, mutton, eggs, fish, poultry, coffee and tea Avithout milk or sugar. I added a little claret Avine if they did not desire the above beverages; the acid and alcohol Avere ingredients conduci\re to re-establishing the process of digestion, and thus preventing fermentations. I forbade pork, milk, molasses, potatoes, fresh bread and pastry gener- ally. I ordered baths in salt Avater three times a Aveek, and kept the children out in the air and Avarmly clad. Medical Treatment.—It is in such cases that any laAv or school of medicine is to be put aside; the action of the medicament must be sufficient to permeate the excre- menta with its morbific influence, and kill the parasite and its ova. It cannot feed upon the secretions that do not contain milky emulsion or saccharine "materials, 100 PROGRESSIVE MEDICINE. much less upon such things as oleum terebinthinse chenepodium, or santonine. $. Pomgranatum cortex, f ii. Aqua (tAVO pints), 0 ii. Boiled for tAvo hours and strained; one half Avine- glass before meals. This infusion Avas meant to act as a medical wash of the stomach and intestines. They took the remedy for seven days. I had the pleasure of seeing an improvement, and directed that the remedy should be continued a week longer. They came to see me on the fourteenth day, and their cheerful faces and brighter color Avere unmis- takable signs of returning health. The father reported that the stools Avere no longer loose or clay colored, but yellow and of a certain consistency. Bunches of dead parasites Avere seen in the faeces; after this the appetite became more natural and the sleep undisturbed. I thought it proper to change the remedy, as I did not Avish the system to get accustomed to it and thus lose its influence. 5L Pulv. Kousso, 1-dec. 3; M. et devid. chart, xxx. Dose—one powder every two hours to each child and the mother also. The same diet Avas continued. On the fourth Aveek they still reported progress; but to insure a cure I ordered: #. 01. Terebinthinae, 3-dec. f; M. et divided in chart. xxx. Dose—one poAvder every three hours. On the sixth week they reported themselves Avell. These were inter- esting cases, and shoAved that Avhere strong, irritating, and purging anthelmintic medicines had failed, a judicious diagnosis and light therapeutic treatment, Avith small doses, succeeded beyond question. The first and main object Avas to re-establish nutrition and physical force; and secondly to starve the parasite instead of driving them out by mere mechanical or chemical means. The therapeutic idea Avas to permeate the intestinal excretions Avith an offensive ingredient, mixed with the DISEASES FROM IMPERFECT NUTRITION. 101 fluids of the intestinal canal, but not sufficiently strong to cause irritabilities or mechanical evacuations. This process would have had the effect of gradually destroy- ing the imbedded parasites. The question Avith us is to use remedies by the laAv of similarity, but helminthiasis is one of the anomalies to Avhich Similia has no relation. It is purely a parasitic disease, and not a dynamical one. We do not claim that Homeopathy will produce ver- mine; neither can the Rational school claim any system- atic treatment. Both employ a general treatment, tak- ing as points of direction the diathesis, idiosyncrasies, and predisposing surroundings. The small doses per- meate, together with the fluids, the faeces, and enter in- to the mucous corrugations; and thus Ave explain the action of an infusion or a trituration, having a decided advantage upon massive doses, Avhich, it is true, expel large worms, but never cure helminthiasis as a consti- tutional disease. CLINICAL CASE VI. During my practice in Washington city, in 1866-68, a lady applied to me for medical advice. She Avas thirty- three years old, unmarried, and a clerk in the Treasury Department. Physical Examination.—The rhythmical action of the heart Avas not normal, the systolic sound Avas short and increased in force. No hypertrophy could be discovered. Stomach sen- sitive to the touch; no indication of ulceration. Intes- tines bloated Avith gas. Tongue coated yelloAv, with a slimy fur. Liver someAvhat enlarged, hard and tender on the loAver lobe. Lungs sound. Kidneys irritable from a strong ammoniated urine. Uterus perfectly sound, organically and functionally. Menstruation regu- lar. Respiration slow and labored. Pulse full, bound- 102 PROGRESSIVE MEDICINE. ing up to sixty-five to the minute. Physical develop- ment generally good. Semiology.—She Avas of dark complexion and bilious lymphatic temperament and diathesis. Her appearance Avas of a pale and faded hue and she had yelloAvish spots on her face and neck. Her habits Avere regular and her occupation confined her to the office from 9 A. M. to 4 p. m., and no exercise Avas taken. She complained of having lost strength, flesh, and appetite. Her mind dwelt a good deal upon her physical condi- tion, and she felt as though life Avas a burden to her. , She had no ambition to Avork, no taste for amusements or inclination to exertion. In her former life she had been actively employed in domestic duties. Her family were healthy and she could not recollect that any members Avere subject to any particular constitu- tional trouble. The district she lived in Avas healthy, hilly, and in the north. There Avere no illusory symptoms, from the effect of a morbid, imaginative, or hysterical mind.- I could not trace her trouble to malarious diathesis or idiosyncra- sies. She had never been exposed to any sudden change of temperature, vexations, or sorroAv. No do- mestic troubles, no blighted affection Avere the cause. She indulged in no intemperance or late hours. She suffered with periodical frontal headaches. She was chilly, alternating Avith hot flushes along the spine. Head burning hot and heavy; cold feet and hands; loss of appetite; eyes lifeless, pupils contracted; pain in the back; urine scanty and of a dark color; specific gravity—1020 to 1025, Avith a sediment of phosphate of ammonia; eructations of sour, bitter taste; pain under the scapula and in the region of the liver (not constant). She was insomnious, taciturn, and fond of solitude; had lost all her energy; felt drowsy, and yet could not DISEASES FROM IMPERFECT NUTRITION. 1C3 sleep; sparks before her eyes, Avith vertigo and nausea. She had taken advice from some physicians of the old school, but they gave her cathartics, bitters or tonics, which had neither permanent or curative effects. Etiology.—Gastro-hepatic derangement. The liver was engorged with slow circulation and biliary reten- tion, and the whole digestive tract was affected by it. The juices were acidulous and the assimilation Avas sIoav and imperfect. The chylopoietic viscera Avere perform- ing their physical and organic functions imperfectlv. The absorbents were all torpid. This organic and physical condition had been brought about by confine- ment in heated rooms and boarding-house diet and insufficient exercise—perhaps, also, loneliness and Avant of friends and cheerful amusements. Biliary engorgement or retention is most generally followed by great nervous, sympathetic symptoms—as depression, irritability, chills, hot flushes, and mental disorder like hypochondria, or hallucinations. There are three conditions by which this great organ can be affected: 1. Organically by malaria and the vicis- situdes of debauchery; 2. By anaemia and feebleness; and 3. Bv nervous irritability and reflex influences from the digestive organs. Minor troubles might be enumer- ated, but they come under the same category of patho- logical lesions. The afferent and efferent functions are often sluggish and cause engorgement. It is of the highest importance to knoAv the organic and physical conditions of the liver before medicating it. Is it hy- peraemia or biliary engorgement, or both ? Is this pathological condition organic or functional? Is it from reflex influences, or idiopathic or pathognomonic of the organ ? Is it hereditary or acq uired ? Is it neurosis ? Is it malarious poison, or high living and hypertrophy, or anaemia and atrophy? In the first morbid condition we have both tumefaction of the liver and atrophy and invariably joined with splenic complications. 104 PROGRESSIVE MEDICINE. I must premise that I have no fancy for liver doctors; nor do I consider that organ deserving of blame so often. The erroneous attacks upon it are frequent, and often Avithout a scintilla of reason. In mental depressions the functions of the liver may be affected abnormally, but the question arises Avith the physician, or should arise—Is it the liver, or the brain? If the first is decided upon, it must be on close and unmistakable physical examination, and careful diag- nosis, and Avith Avhat pathological condition the organ is affected. If the second is decided upon, then the conclusion is, that the afferent and efferent functions of that organ are morbidly affected by reflex influence or neurosis. In all cases of disease of the chylopoietic viscera, or stomach, generically called dyspepsia, the liver is in- volved ; but is it sympathetically affected by mal-as- similation and inanition, or are the functions of the liver idiopathically affected, and are the lesions organic or only functional ? In the hot climate of India there are the insidious hepatic disintegrations, a path- ognomonic condition of the disease caused by destruc- tive materia-inorbi. There are, also, from various physi- cal causes, cacoplastic formations in the organ itself. Noav, are the cathartics—drastic cathartics—saline cathartics, etc.—given so often by the Rational school, the proper agents to be so indiscriminately used Avhen hepatic diseases proceed from sympathetic influences, either objective or subjective? The liver, Avhen involved Avith the faulty process of chylification, suffers not only from sympathy, but from inanition, and consequently produces acidulous greenish bile and enfeebled organic action. Would cathartics be advisable to bring about a forced action, temporary and reactive, or retrogressive and debilitating? Would that be a rational treatment? But invariably in all cases of suppression of biliary DISEASES FROM IMPERFECT NUTRITION. 105 secretion the remedy is Avithout any further physical inquiry than a good cathartic, which, of course, pro- duces a temporary mechanical action, at the expense of organic reaction, and increased debility. This system of purging Avith drastic cathartics is to be deprecated as supremely injurious, and producing incurable diseases of the liver. There are so many natural Avays of get- ting at torpid organic functions Avithout these irritating, exciting, depleting, and debilitating processes. The physical examination and semiology Avere sufficiently suggestive that Ave had a case of idiopathic liver trouble. I stated that the diagnosis pointed out the true con- dition of the organ, which Avas biliary suppression. It is a physical disarrangement of the nucleoli, Avhich are unable to act upon the infiltration of the biliary fluid, and conduct it into the little intercellular ducts for exit by way of the ductus communis. The impure venous blood goes on to the greater circulation and poisons the Avhole system. But, had I made my diagnosis as retention, then I should have meant that the organ had performed its physical and organic functions, but that it or its chan- nels Avere obstructed, either by Avant of force or by tumefaction from an acute or chronic inflammation, hence retention. Had Ave irritability, nervous excite- ment, and agitation, from physical or mental disturb- ance, then Ave Avould have a contrary condition, i. e., hyper-secretion, colic, diarrhoea, vomiting, fever, jaun- dice, high bounding pulse, mania, suppression of urine, and possibly red eruptions in spots throughout, Avith, per- haps, other complications of a cerebral order. But these cases proceeding from other diseases are reflected upon the liver by a physical co-ordination of forces and func- tions, differing from ordinary idiopathic liver diseases. This condition of inactivity of organic action Avas brought about by enervation, caused by general mal- 106 PROGRESSIVE-MEDICINE. assimilation and nutrition. The constitution and blood were enfeebled by these causes, and the nervous system and organic functions became affected. Hygiene.—Bathing in salt, warm water, exercise in the open air, and light animal food, the amylaceous predominating. Diet.—Leguminous—oatmeal, peas, baked potatoes, milk, spinach, rice, sago; Nitrogenous — mutton, chickens, and fish. No pastry or hot bread, no beef, no butter, and no .gravies. Coffee and tea forbidden. Lemonade, claret, Avine and Avater. Medical Treatment. — #. Nitro-hydrochloric acid; pepsine. The usual formula—one tablespoonful after meals. Hot fomentations to the liver. After one week of this treatment, I changed for: $. Nux-vomic, 3-dec. gutt. xxx. Aqua distill., f iii. #. Podophyl., 3-dec. grs. xxiv. M. chart, xii. Dose—one teaspoonful every tAvo hours, alternately with one poAvder. She took these remedies for a Aveek longer. Her appetite returned, the tumefaction of the liver disappeared, the bowels became regular, the skin of a normal color, the pulse returned to a normal con- dition, and her nervous system gained its force and equilibrium. CLINICAL CASE VII. A Mrs. Keith, a married lady Avith three children, thirty years old, of a lymphatico-phlegmatic tem- perament. She had been sick for several years, and had employed both schools Avithout any prospect of cure. Physical Signs.—The lady Avas Avell developed, of broAvn complexion and blue eyes, having a tendency to fatness. Heart sound, and the rhythms Avere perfectly DISEASES FROM IMPERFECT NUTRITION. 107 regular; lungs healthy; menstruation regular; kidneys normal, both structurally and functionally. Semiology.—When I first saAV her I found her lying down, and suffering with cardialgia and the most pro- fuse pyrosis. The pain extended spasmodically all over the stomach, and Avas more common in the fall and spring. Excitement of any kind would bring on a par- oxysm of pain, Avith pyrosis. Exercise Avas impossible, and even singing Avas out of the question. She had eructations of sulphurated hydrogen, and an offensive breath. Food did not distress her, and she had a good appetite. I examined the saliva and the contents of the stomach, and found a great quantity of ropy, exces- sively acidulous mucous and of a yelloAvish color. She had to keep a handkerchief constantly upon her pillow for cleanliness. Night and day she Avas equally affected. I became quite anxious, as she Avas very desponding. The ganglionic system Avas excessively sensitive, and she Avas very excitable and imaginative. Her boAvels Avere regular and Avere free from any complications of the liver. She Avas very feeble on account of this great loss of mucous. I could not detect any ulcera- tions, but the hypersecretions seemed to proceed from a physiological derangement of the secretions, i. e., sali- va and gastric juice. The alkalinity of the salivary secretion Avas not normal, and her food did not contain a sufficiency of alkaline elements, hence the lactic acid abounded, and, together Avith the gastric juice, produced this terrible irritability and hyperaemia. But Avas not the nervous system primarily the cause and secondarily the effect? Etiology.—I considered it a case of irritability of the mucous follicles of the stomach, Avith a sympathetic ner- a^ous hyperesthesia, caused, in the first place, by a change in the constituents of the salivary fluid, and 108 PROGRESSIVE MEDICINE. second, of the gastric juice. The remote cause was a predisposition to mucosities. The exciting cause an abuse of saccharine articles. The pathognomonic symp- toms Avere like those of ptyalism by some irritating substance. The disease Avas evidently one of a cliemico-physio- logical nature, Avhicli brought about a hyper-secretion of the mucous membranes, the follicles, and the salivary glands; idiopathic and idiosyncratic to her constitution. There Avas no other appreciable cause to account for it. It became organic as it Avas alloAved to become chronic; and finally it produced a nervous hyperesthe- sia, a natural consequence of a continuous drain of the secretions. This demonstrates forcibly the usefulness of a differential diagnosis betAveen cause and effect. The pathognomonic lesion Avas organic and not func- tional. The nervous symptoms and the pain Avere sym- pathetic. This pathological metamorphosis presented certainly irritability and hyperaemia, but neither entirely inflamma- tory or nervous. Pyrosis Avas a symptom, a feature, indicating a deep seated trouble in the organs of secre- tion ; but not the disease itself. To treat merely a hypersecretion Avould be like treating a sick headache, caused by injesta, or gastric crudities alone. In this case there Avas no indigestion, supposed to be the offend- ing materia morbi, but an organic disease, as a phenom- enon of irritability. Although Ave haA-e admitted hyperaemia and hyper- sesthesia, yet still Ave could not admit an anti-phlogistic treatment or an antispasmodic one. There Avas neither inflammation or sthenia, per se. The bleeding and blistering of the old school, or the hypnotic, Avould have proved an unfortunate delusion. Looking at the disease from a logical point of vieAv, I could only hope for success in a treatment on a cliemico- physiological plane—the only one possible for relief and DISEASES FROM IMPERFECT NUTRITION. 109 cure. Antispasmodic medicines and the hypodermic injections had been used, as Avell as the astringent ton- ics, Avithout success. The old school had exhausted its science and eclectic theories, and there Avas nothing but true similia that could possibly do any good, on the basis of physiology. Therefore the practitioner of similia should direct the remedies he employs to be cliemico-physiological in their action. I prescribed kali chloras 1-10, in tAvo grains poAvder, every tAvo hours. The emotional sys- tem Avas engaged, therefore I gave belladonna 3-dec, alternately. Dose—One poAvder every alternate hour. Two days after I found her better. The pyrosis Avas less copious and the nervous irritability Avas diminished. I recollected tAvo more points of my diagnosis, ATiz., offensive breath and sAveetish taste in the mouth. I ordered: fi. Kali chloras, 1-dec. 3 i. Aqua distill., f iv. #. Carbo vegetabilis, 1-dec. 3 i. Aqua distill., f iv. Dose—One teaspoonful of each every tAAro hours alter- nately. She Avent on with this treatment, and improved in many respects. The odor and 3-elloAvish color of the secretions Avas corrected, but the pain in the stomach returned at night. On the fourth Aveek I prescribed: #. Natrum muriat., 3-dec. 3 i. Aqua distill. ^ iv. ty. Bismuth subnitratis, 1-dec. 3 i. M. et devid. chart, xxiv. The fifth Aveek she felt much better, she Avent to church and sang in the choir during the service. Next day I Avas called to see her. She had suffered all night Avith gastralgia and pyrosis. 110 PROGRESSIVE MEDICINE. It was evident that she Avas not cured, although she was much improved. The Homeopathic treatment Avhich had been used before had had no effect; and the laAv of similarity had been exhausted, and almost noth- ing seemed to be left for her relief. I prescribed the folloAving remedy. #. Iris florent., 1-dec. 3 i. Aqua distill, f iv. Dose—One teaspoonful every tAvo hours. The result was surprising. She expressed herself very much relieved, and felt that I had found the right remedy. Hygienic and Dietetic Treatment.—In this case I had little trouble in selecting the proper diet, because she could eat everything with impunity; but yet she Avas only allowed cream, mutton or beef broth, chicken broth, rice, oyster juice, and the like. No vegetables Avere alloAved, but old bread, crackers, and rye bread Avere advised. This case suggested strongly the want of cyanide of potass in the salivary secretions, a necessary ingredient to elementary digestion. In former prescriptions I have endeavored to supply it; in this last remedy, I only found a neurotic to serve my purpose, and thus removTed a ganglionic influence. She gained flesh and general health. I believe this treatment will meet with the approbation of the profes- sion generally. CLINICAL CASE VIII. This case, although similar in many respects to the preceding ones, has some peculiar points of its oAvn, which are to be found in the intensity of the symptoms and the complications connected Avith it. Unless our mirror is at fault and our light deceptive, the most important features of the case are reflected in a very suggestive manner. There are a great variety DISEASES FROM IMPERFECT NUTRITION. Ill of symptoms, differing in shades and indications, but easily distinguished by the practiced eye. The useful- ness of taking into consideration all symptoms is to be recommended, but the important point is to take in the salient points of the true pathological conditions, thus directing your attention to them as the unmistakable signs of a certain physical or organic manifestation. The minor symptoms are generally sympathetic and secondary. Mrs. N., forty-eight years old, of a nervo-bilious dia- thesis, dark complexion, Avell-developed, and the mother of three children. She had enjoyed good health and an easy, comfortable life. Perhaps her mode of living Avell, and a sedentary life had predisposed her to gastric troubles; and, indeed, she recognized that fact herself. Physical Examination.—Heart and lungs Avere sound; kidneys normal, yet the urine was scanty and of a heavy specific gravity, 1000-30, Avith a bilious cast. Liver large and someAvhat hard and torpid. Stomach very irritable. BoAvels inflated Avith constipation. Skin dry and yellowish. Her mental faculties Avere blunted; she could not arrange thoughts and connect ideas. Great and general prostration. Semiology.—I Avas called to see her very early in the morning in the fall of 1869. I found her in her bed, suffering intensely from the stomach and intestines, gastro-enteralgia. A great quantity of flatus had accu- mulated in the stomach and boAvels. She had nausea, and her tongue Avas coated Avith a yelloAvish Avhite slime. The abdomen was tympanitic and the stomach very sensitive to the touch. She made several efforts to vomit, but unsuccessfully. The spasmodic contraction of the muscular coat of the stomach and bowels upon the inflated organs produced the most excruciating agonies. She was restless, and had been sick for eight hours. 112 PROGRESSIVE MEDICINE. The pressure of the gas upon the iliac veins obstruct- ed the portal circulation, and consequently the systemic circulation was altered. She was threatened Avith syncopy; pulse small; ex- tremities cold, Avith a cold perspiration, threatening collapse. The nerA^ous system Avas so agitated and so severely tossed about that the danger Avas a temporary suspension of the great vis-vitae, and perhaps death. The splanchnic nerves Avere particularly affected. The contraction of every capillary Avas so materially dangerous that the heart Avas fluttering, jumping, and relaxing at a fearful rate. The symptoms Avere truly alarming. Respiration short and quick; in fact she could not inflate the lungs, as the diaphragm Avas unable to move doAvinvards on account of the great inflation. The force from vis-atergo being disarranged, the Avhole circulation Avas in a critical state. She had been constipated for some weeks, and sour- ness and pyrosis Avere the harbingers of the present condition. Her digestion had been poor for years, and she had suffered Avith dyspepsia every spring and fall. The gas Avas odorless, because of carbonic acid fer- mentation. The bitter, sour taste indicated a sIoav abnormal process of chymification and passing unpre- pared chyme upon the process of the chylopoietic viscera. This disarrangement of the stomach produced that of the intestinal canal. The liver also had its indirect effect, by not passing the bile into the intestines, hence inflation from fermenta- tion. It is a Avell-knoAvn fact that bile has a material influence upon chylification, and upon the effete mate- rials throAvn out as a Avaste, in preventing fermentation by its pungent carboniferous fluid, Avhich is the result of decomposition of the venous circulation, and, to some extent, is mixed with a nitrogenous element. The hydro-carbon is absorbed, while the yellow, nitrogenous, DISEASES FROM IMPERFECT NUTRITION. 113 effete part of the bile goes out Avith the faeces. Noav, then, the hydro-carbon is the glucose part of the biliary secretion, and aids in the calorifacient process of intes- tinal digestion. The physical and physiological func- tions of this organ are Avell knoAvn. These feAv lines of elementary principles will refresh our memory as to the difference betAveen suppression and retention, and bring it more forcibly in comparison Avith our clinical cases. We must folloAV the diseases appertaining to the diges- tive organs upon a physiological knoAvledge of their suppressed functions. The link is Avell connected, and the chain is so closely dependent upon CArery link being sound, that mistakes are often made by the best of physicians. Then comes the question, Avas not this mischief the result of bad chymification in the first place, and the liver and chylification secondarily affected? The tAvo processes are so dependent upon one another that very rarely do Ave have the stomach affected Avith- out the enteric juices feeling the effect of it. Yet there are such cases, both gastric and intestinal being singly disarranged; then, of course, the difficulty is easily recognized. And just at this juncture comes the ques- tion of nitrogenized and histogenetic digestion, and hence, whether the elements of nutrition, Avhich are mal-assimilated, belong to the former or latter class; in other words, a\ hether Ave should prescribe this or that kind of nutrients. With this comes the idiosyncrasies of the diathesis and predispositions thereof, and again, the exciting causes. With this strong diagnostic force in hand, the probabilities are that avo cannot go far astray from the true course of treatment. It is obvious that high-living individuals arc often affected by liver complaints, because of the large amount of effete ele- ments in the A-enous blood, Avhich the organ is not always able to filter through its cells. We have another condition, and just the opposite of the first, i. e., mal- 114 PROGRESSIVE MEDICINE. nutrition from improper food, or semi-starvation. In those cases Ave haA^e also hepatic diseases arising from organic debility caused by physical inanition. While Ave Avould do Avell to prescribe an abstemious regimen to the former, Ave should prescribe a generous one to the latter. While amylaceous food Avould do for the first, the nitrogenized should be given to the second. Frequently we have organic or structural diseases of the liver, caused by climatic causes or constitutional rea- sons ; but in the largest percentage, the hepatic regions are affected by an imperfect process of alimentation and digestion. It is not ahva}Ts the liver that suffers, but the lungs, heart, and kidneys. Morbid cachexia of the nervous system, gouty affections, etc., often result from mal-as- similation and mal-nutrition. Melancholia, hysteria, hypochondria, asthenia, and even mental aberrations, epilepsy, helminthiasis, etc. The last are the innumer- able cutaneous affections Avhich cause so much suffering, and from Avhich none are exempt—neither the gour- mand or the beggar, the plethoric or the anaemic. Etiology.—1. The bilio-nervous diathesis predisposed her to hepatic complications. Her idiosyncrasies Avere lymphatic and predisposed her to leucophemia. She might have been classed amongst the hyperplastic lymphoma. She inherited a long life, and her constitu- tion Avas strong and Avell developed. 2. High living and indulgence in luxuries and pastry. 3. Excessive use of coffee, late hours and suppers. 4. Sedentary life and hot rooms in the Avinter. 5. Of late, mental anxieties, on account of financial troubles of her improvident husband, Avas one of the principal exciting causes. These and other minor humiliations produced a sympathetic or emotional influence upon the delicate organs. Hygiene.—Nothing could be suggested except bath- DISEASES FROM IMPERFECT NUTRITION. 115 ing. Exercise, early hours in retiring and rising, and a protective flannel around the stomach and bowels. Dietetics.—Mutton broth, beef-tea, oyster-soup, but not the oysters, clams, mutton chops, and chicken. The albuminous and amylaceous articles of diet Avere for- bidden, as she had the difficulty of an enfeebled chyli- fication. Medical Treatment.—The case Avas severe and required immediate relief, by Avhich I do not mean an entire cure. #. Tinct. Assafcetida, f i. Aqua bulientis, f iv. M. Injection—one quarter at a time. p. Lycopodium, 3-dec. 3 i. Aqua distill., f ii. Dose—One teaspoonful every fifteen minutes; and hot poultices applied to the abdomen, Avith drinks of hot water added. She soon became quiet, and slept for half an hour. Then a free evacuation of the boAvels took place. She Avas much relieved and the eructations from the stomach Avere excessive. But yet at times she felt the pains coming back. I gave another injection Avith assafcetida and a feAv doses of lycopodium and the hot drinks. She slept again for over an hour, and had another large evacuation with a great amount of gas. I made an ex- amination and found the abdomen relaxed, no pain in the stomach, and no pain on touching it, except that of great soreness. I continued the hot fomentations. #. Merc, alkalizatum, 3-dec. 3 sj. M. chart, xv. #. Lycopod., 3-dec. 3 i. Aqua distill., ? ii. Dose—OnepoAA'der every hour alternately with a tea- 116 PROGRESSIVE MEDICINE. spoonful of the liquid. At the sixth hour she Avas con- valescent. I left her in the afternoon comfortable, and returned next day. I found her still more comfortable, and she told me she had had several copious evacuations, Avhich relieved her very much. I continued the treatment all the second and third days. On the fourth, I gave her no medicine, nor the fifth. On the sixth day, I com- menced my curative treatment on a cliemico-physiologi- cal basis. The first tAvo remedies I considered thoroughly Homeopathic, having dynamic effects upon the nervous system and secretions as well; but the main object Avas to remove the offensive matter, and add agents that Avould stimulate hepatic action and nervous influence; this Avas accomplished. There Avere many other reme- dies indicated as Avell, e. g., colocynthis, aloes, nux vom., camphora, belladonna, natrum carbon, etc. The object of the folloAving treatment Avas to aid the vis medica- tricae naturae on a logical principle. Have Ave not ad- mitted the want of chymification, and the enteric or chylopoietic derangement in consequence? We have also seen the effect of this mal-assimilation upon the liver, hence Ave can suggest remedies that have a direct and specific influence upon those organizing processes. I prescribed: #. Acid hydrochl. dil., 3 ii. Pulv. pepsine, 3 ii. Aqua bulient., ^ ii. Dose—One teaspoonful every four hours, or after eat- ing. #. Pulv. aloes, 3-dec. 3 i. M. chart, xxx. One poAvder every tAvo hours. She recovered entirely, and never aftenvards had a similar attack during my residence there, which was four years in length. DISEASES FROM IMPERFECT NUTRITION. 117 CLINICAL CASE IX. Miss C, an unmarried young lady of twenty summers, of a nervous, lymphatic temperament, of small stature, gray eyes, and regular habits. She complained of much pain in the cardiac region of the stomach, and particu- larly after eating. Physical Examination.—Heart sound. Lungs in a normal condition. Kidneys irritable, Avith a heavy yel- lowish shade of the urine. At times she found a Avhite sediment at the bottom of the vessel, Avith strong ammoniacal odor. Stomach tender to the touch. Liver enlarged and rough, not having that natural smooth surface of the normal organ; tender on touch. Conjunctiva of the eyes of a yelloAv- ish color. Skin rough and dry, impregnated Avith yel- lowish pigment. Semiology.—Constipation; very irritable; sad, gloomy thoughts; insomnia; headache; great exhaustion and Aveeping; pulse Aveak and compressible; countenance haggard; tongue coated Avhite at the edges and slimy yellow in the middle. She had a voracious appetite, and could eat at all times. She tasted her food after eating for a long time; pain in the epigastrium. Flatulency and eructations annoyed her constantly. She suffered Avith pain under the right scapular, short breath, and cold chills running doAvn her back. She was so feeble that everything tired her beyond measure. Her menstruations Avere regular. Urine of a heavy specific gravity—1000-31. Eructations Avere often sour and bitter, and breath offensive. Her Avhole organism was affected by this devitalizing mal-assimilation, and the physico-vital forces Avere steadily undermined. She Avas fat, but asthenic, and inanition was threaten- ing. The gastro-hepatic and enteric symptoms Avere those of a se\Tere case of mal-nutrition. The nitrogenizedand 118 PROGRESSIVE MEDICINE. non-nitrogenized elements AArere both equally and im- perfectly organized. The blood became poor and serous —the fats only Avere einulsionized and kept her looking Avell—and so the tissues Avere scantily repaired. Ani- mal heat and combustion, so necessary for the process of decomposition and composition, Avere at a Ioav degree. Her Avhole economy Avas fast descending, as the blood- cells Avere losing the haematine, and becoming inactive and Avasted. Leucothemia Avould soon have had the supremacy, and cacoplastic formations, or some malig- nant or devitalizing disease of a Ioav form Avould have been the unavoidable result. Often dyspeptic people are faf. Etiology.—She Avas indiscreet in eating, and very fond of pastry and molasses. She indulged in the heavy kind of badly-cooked food prevalent in the country— sausages, pork, ham, and fried cakes and meats; hot bread and pies, ad libitum. She took no exercise in the open air, although she had some domestic occupations. Slept on a feather-bed and in closed rooms. Ablutions Avere more of a novelty than a daily or Aveekly duty. Pudding, potatoes, and candies Avere the delicacies in which she found pleasure. This sums up the Avhole history of the case. It Avas idiopathic, and neither dia- thesis nor inheritance had anything Avhatever to do Avith it. The enervation and the hepatic complications Avere subjective symptoms produced by the same cause. The organic functions of the liver Avere torpid in conse- quence of too much alimentation; the cells Avere filling Avith the fats from the alimentary canal, and the abun- dance of it acidulated the chyle, to some extent, and the process of histogenesis Avas consequently impaired from an imperfect organization of proteine compounds. The symptoms of enervation and excitability were obviously duo to the described condition of her general system. A reflex influence Avas brought from the sym- DISEASES FROM IMPERFECT NUTRITION. 119 pathetic filaments to the ganglia, and from there to the centre. Both the centripetal and centrifugal forces Avere in a stale of hyperesthesia. In these cases Ave often find the so-called sick headaches, menstrual disturbances, and renal complications. The gastro-enteric juices had be- come enfeebled and acidulated. She had employed a Rational physician (Allopath), and therefore took physics and tonics secundem artem, but the trouble Avas never removed. Hygiene.—Bathing and hot applications to the liver were ordered. Walking and riding in the open air Avere also obserAred. Dietetics.—This Avas the great general difficulty, for she Avas young, had a good appetite, and Avas unruly. Fish, oysters, clams, dry toast, old bread—no butter—mut- ton, and chicken, Avith tomatoes, lettuce, or green cab- bage Avith vinegar. The acidity of which she com- plained Avas not from an over-abundance of gastrc juice; it Avas the result of greasy food, Avhich became butyric acid. She did not have the symptoms of gastritis from a hypersecretion of gastric acid, but more from the result of fats and fermentation. But if the food had been of a proper quantity and kind, the organizing prin- ciple of the stomach might have been sufficient to perform a normal digestion; but since the abuse of over-nutrition the juice and peptones had been very much enfeebled, and hence the necessity of bringing artificial agencies to add the elements required. Medical Treatment.— #. Hydrochlor. acid diluted, 3 i. Pepsine, 3 i. Aqua bulientis, f iv. #. Nux vom., 3-dec. gutt., xxiv. Aqua distill., s iv. Dose—Tavo teaspoonfuls of the digestive agent after 120 PROGRESSIVE MEDICINE. eating, and one teaspoonful of the nux every tAvo hours between meals. The first agent to supply chemico-physiological prim ciples; the second, to act upon the nervous force dy- namically. Chemically alone, Ave cannot expect a per- manent and a physical cure, but by adding simply the material wanted, together Avith our dynamics, the recu- perative poAver of nature is frequently re-established. This treatment Avas continued for one week, at the end of which time I saAv the patient much improved and the ct^mification re-established. Nevertheless, there was still much to be done. The liver and calorifacients had not yet returned to their normal functions. #. Podophyl., 3-dec. grs., xxx. M. chart, xx. #. Natrum phosphor., 6-dec. grs, xxx. M. chart., xx. Dose—One poAvder every tAvo hours alternate^. The secretions improved Avonderfully, and she left me before the cure Avas finished. I should have continued Avith bryonia and bella- donna, and finished it with quinia and pyro-phosphate of iron. There are two remedies Avhich I would recommend. viz., iris vers and collinsonia. 121 PART II. CHAPTER I. IDIOSYNCRASIES AND PREDISPOSITION. In the preceding part I have endeavored, by useful and practical illustrations, to support (by clinical cases) the theories Avhich I advanced in my first proposition, i. e., that mal-assimilation and innutrition are frequent causes of a pathological metamorphosis of organic life, Avhich sooner or later must bring about a more general disarrangement of the co-ordination of the physico-vital phenomena. And in this part Ave Avill study a neAV proposition and argument, i. e., the idiosyncrasies and predisposition of the feminine sex to diseases of this nature. Convinced that this is rather a virgin soil, touched only in relation to diseases of Avomen in the nature of uterine and the sexual organs, I make a neAV departure and take up other than the diseases of the generative organs, Avith Avhich the present subject is disconnected, I shall touch only upon the diseases and symptoms proceeding from mal-nutrition and the pathognomonic lesion^, structural and functional, of the organs of diges- tion, Avith the connecting and inseparable chain of the physico-vital phenomena, i. e., the nervous system. It is Avell understood that social position, occupation, nature, climate, atmosphere, domestic relations—-single or married—have much to do Avith these diseases. What mi°dit be only a temporary inconvenience to a man might easily overcome a Avoman, and might produce great 122 PROGRESSIVE MEDICINE. nervous complications, either general or special, centric or excentric; and these may be spinal, cerebro-spinal, cerebral alone, or ganglionic; sometimes circulatory and at others lymphatic. These complications often arise in Avomen Avhile men are almost exempt from them. The ganglionic and lymphatic systems are very much more sensitive in Avomen than in men, more easily put out of equilibrium, thus complicating diseases to a Avonderful degree. The female sexual organs are prone to have a reflex action upon her Avhole organization. Her physical development and force are less enduring, and consequently more easily disarranged and enfeebled, rendering her organ- izing functions difficult and incomplete. The vital force seems to be a prerogative of the female sex: it is a fountain inexhaustible beyond comprehension. This is a relative and co-ordinating force, an offspring of physical and physiological forces; but there is something nascent and peculiar, because if it depended upon the machanical or dynamic forces it AArould most certainly decrease or increase, ascend or descend, according to the physical development and functions of those correlative agencies. Although linked to a large degree Avith other forces, the dynamic possess a peculiar strength, located, as I belie\re, in the ganglionic system, as a focus of supply Avhen there is a necessity for its equipment. With this acceptation Ave must admit an extraor- dinary amount of dynamic force existing in the great sympathetic system of the female. It is already con- ceded that the ganglionic system is greatly developed in Avomen as an idiosyncrasy of their sex. In sensibility, in intelligence, in brilliancy, in endurance of suffering, in affection, in hatred, in quickness of perception, in virtue, in vice, in morality, in religion, in generosity, in avariciousness, she excels the male, and therefore Ave must admit that these qualifications characterize the IDIOSYNCRASIES AND PREDISPOSITION. 123 emotional of the sex as of a finer and more sensitive nature than our OAvn. This Avord sensitive derives its origin from the sensory system of nerves, and avIio doubts that the ganglionic system is the nucleus where a finer ramification of nerves branch off to furnish all the organs, supervise organic functions and circulatory apparatus. These ganglia are found in the cervicle at the base of the brain (the largest), the cardiac ganglia, the lumbar, the sacral, etc. This peculiar dynamic force exists in these ganglia and its nervous filaments. The recuper- ative poAver of nature lies mainly in these ganglia, and the process of nutrition and repair is supervised by this dynamic force, in connection, of course, Avith other forces. From this point of vieAv Ave may study and reflect upon the Avhole field before us in a most scientific and logical manner. In vTieAV of this I feel justified in con- sidering the subject for a study apart from the other sex. Wealth and comforts, Avith ease and a sedentary life, do not promote strength and health. Our ancestors had to work much more than Ave. The inventions of the present day—relieving people from many hard drudg- eries—did not then exist. The convenient arrangements of the range and cook- ing apparatus, the hot and cold Avater constantly at our disposal, the Avashing and the seAving machines, and all the paraphernalia of domestic utensils Avere unknoAvn. Our ancestors had to do all their Avork by hand and endure hardships that Ave have . not. But all this, hard as it appears, gave them strength, fortitude, and patience to bear, together Avith health and strong constitutions. Dissipations Avere feAv in comparison to Avhat Ave have noAV. Dancing, late hours, late dinners, and fashionable 124 PROGRESSIVE MEDICINE. life were limited to a small number. The extravagances of a large number of servants, carriages, and horses were not indulged, except by the richest people. They lived economically and in accordance Avith their means and the laAvs of nature. Music, although very commendable, did not occupy the first place in a young lady's education, nor should the symphonies of Mozart, or the tender notes of Rossini, or the cantatas of a Stabat Mater, or the thrilling operas of Verdi drive out all study of Avhat is practical and useful. And Avhile I touch upon these points I believe that the readings and teachings of this day are not, Avhat Avould prepare young ladies for the hard fight of life, and the prosy and unpalatable acqui- sitions necessary for Avives and mothers. The rudi- ments of Latin, Greek, music, mathematics, algebra, navigation, poetry, chemistry, etc., are deceptions of knowledge. Better be a good houseAvife than a mere varnished, unreal piece of Avhatnot. Better be a good cobbler than a quack doctor, or a charlatan of a laAvyer. The assertion, perhaps, may be questioned, but it is nevertheless true, that in our days of intellectual race, Ave often forget the first principles of Avhat is really es- sential to human happiness and comfort. We are car- ried away with astonishing inventions and discoveries, neglecting, hoAvever, those practical things Avhich form so vividly part of our existence, our morals, our religion, and our character. Do not the above truths prove our flimsy, superficial, and inconsistent interpretation of Avhat should be the education of the young? My opinion is, that if more goodness, charity, and self-denial should be instilled with the true idea of virtue, of duty and moderation, the real essence of nobleness of human nature, the fruits of this peculiar culture Avould be far superior in quality and effects to the superfluous and empty vaga- IDIOSYNCRASIES AND PREDISPOSITION. 125 ries of our present system of education. This does not apply to those whose fortunate lot affords the means and facilities for pursuing scientific and artistic studies to a high degree of usefulness, but simply to the poor girls whose path in life is expected to be arduous and practical. Progress and civilization have brought us many ad- vantages, many comforts, and many social improvements; yet the matrons of old had stamina and stoical principles of right, the correct idea of Avork, appreciation of fru- gality and honor, and devotion to their duty and their families, of Avhich we stand much in need in this pro- gressive century. As illustrations bring fonvard the proofs and facts of the subject in question, the demonstration should be made by separating the sex into tAvo grand divisions: First, those in' affluence and comforts, and second, those Avhom God has intended to labor for their daily bread. Nature seems to adapt itself to circumstance, and renders the human system fit for its Avork and exi- gencies. Those Avhom destiny has placed in the labor- atory of activity become large in frame and strong in health, and meet the duties of their calling Avith pa- tience, perseverance, and contentment. The peasantry of Europe are Avell knoAvn for their hardihood, and their offspring are gifted Avith remarkable physical strength; they are free from the myriads of ailments to Avhich the people of affluence are constantly subject. They are particularly free from diseases of the di- gestive organs. Nervous troubles are almost unknoAvn amongst them. Their maladies are generally acute and serious. Their simplicity of living, their methodical habits of rest, Avork, and food, their unexcited imagination, etc., leave them a freshness, a modulated disposition and SAveetness of temperament pleasant to behold. 126 PROGRESSIVE MEDICINE. True, their superficial beauty, perhaps, soon changes for hardness and solidity of constitution and form, but they lose nothing of their physical force and vital vigor. The wives and daughters of artisans, tradesmen, and mechanics are not always living a life of simplicity; they are generally congregated in toAvns and cities; they do not always possess the blessings of unalloyed morality, rural primitiveness, and frugality; vices of various kinds creep in amongst them. The vanity of dress, and the love of external appearances and embel- lishments, destroy many homes Avhich otherAvise would be happy. These unfortunate weaknesses lead them astray from the path of duty and honor, and miseries, heart-aches, poverty, and domestic quarrels soon ruin the very foundation of their existence. The deceitful pleasing attractions of amusements; the apparent easy and com- fortable mode of living; the gay street and stores, and the beAvitching fashions carry them into many pitfalls, which their country sisters are not exposed to. The comparison is too vivid and true, and Avhile the country girls Avork hard, dress unbecomingly, and live in secluded houses, they lead a life of morality and modesty, Avhich has for its reAvard contentment, cheerfulness, comfort, and, above all, happy homes and pure consciences. Would any one change the rural country life for the many trials, disappointments, and bitter tears of the poor city Avoman? The above is one class of women, only situated dif- ferently in life, and hence different are the -conse- quences. We Avill noAV look at the affluent class, Avhom fortune has favored with comforts and plenty, and therefore it Avould be but logical to suppose them the fairies of the promised land. On a superficial view of the sub- ject it might appear very possible, but deeper researches IDIOSYNCRASIES AND PREDISPOSITION. 127 soon undeceive the observer and open his eyes to the sad realities of an artificial life. This higher and intellectual class of women have also a certain destiny to fulfill, namely, the education, ornamentation, and refinement of society. They ha\Te to encourage industry and labor, fine arts, belles-lettres, and literary societies and pursuits. These are the Avives and daughters of our legislators, laAvyers, merchants, bankers, doctors, and professors. These are they Avho fill the fashionable theatres, the Avatering-places, the ball-rooms, hotels, stores, millineries, etc. These are the elements that give tone and taste to society, and to them Ave are indebted for much that is beautiful and aesthetic. It is also true that they are not only the companions of our best men, but they are the motive poAver of all our great exertions and enterprises; in fact, they are the magnet to Avhich all our mental efforts are attracted for admiration and approval. This is good and providential for the progress of the human family. The benefits arising from this feminine influence could not be demonstrated. It is a mountain of good whose volcano throws to the surface fountains of bless- ings. From the silent atelier of the painter, and from the stu- dent's room, to the chemist's laboratory and the invent- or's mechanical apparatus, Avoman is the motive force —the genius that supplies the incentive element, " the poAver behind the throne," and her ambition is the true spur to man's intellectual development. These tAvo great classes, although diverging in their peculiar positions and occupations, form the grand total of the human and social family—both useful in their particular departments, and both addicted to indulgences and vice, to virtue, industry, and moral- ity. The systems adopted must naturally be different; and Avhile the higher class of Avomen seem to have gifts that others have not, they have also relative responsi- 128 PROGRESSIVE MEDICINE. bilities, duties, and trials that those in a lower sphere of life can hardly appreciate. And now it is Avell that I should return to our medi- cal subject; believing that much illness is the result of deviations from a plain and simple mode of life, especi- ally when replaced by the artificialities of society. This previous comparison will sufficiently demonstrate, the force of my argument. It is not ahvays the case that dissipations are inten- tional, but the false impressions and notions of Avhat is good and healthy lead to them. The prevailing idea seems to be that the more food is consumed, the more wines, liquors, and stimulants of various kinds are used, the more completely are life and vitality supplied Avith the elements of nutrition; but they are often disap- pointed Avhen the results fall short of the mark. If oxygen is necessary for vitalizing the blood, they add food, and hence carbon. If they require motion, heat, and decomposition, they add rest, indolence, and stimulants instead. If they require mental and physi- cal activity, they Avaste it on balls, fashions, novels, etc. They seek to devitalize, exhaust, and neglect every principle, every organizing function, hence nutrition and physical force gradually descend to asthenia and inani- tion, bringing Avith it adynaemia. Our present knoAvledge of physiological laws and functions demonstrates the fallacy of the principle of indulgence. Nutrition and force depend upon the agency of simple elements, but in connection Avith it, Ave require physical influences from the outside, i. e., air, motion, light, electricity, and Avater. So, really, life is sustained by two grand principles, nutrition internal and nutrition external—one animal, the other physical. From these tAvo principles we re- ceive the recuperative and repairing forces. Should the physical laws be guided differently, the gourmand, the wealthy, and all those that enjoy the IDIOSYNCRASIES AND PREDISPOSITION. 129 riches of the country, Avould be stronger and healthier in proportion. Where could Ave find muscle enough to Avork our coal mines, our railroads, our canals, our farms, and our factories? If force should be adequate to the amount of food taken, or of stimulants drank, the rich alone could perform manual labor. But the reverse happens to be the case. The tem- perate class, Avhose judgment and education have taught them to use what is right and proper, and to avoid abuse are those avIio are reAvarded Avith strength and health. Women, above all, are those that should learn Avell these principles, for they are, to a great extent, the basis of social happiness and national strength; they are the promoters of home comforts; the health of future gen- erations, and intellectual development. The rules of hygiene particularly conduce, Avith proper food, to en- hance physical force. Mentally, Avoman is impression- able, easily excited, and imaginative, therefore it is necessary to inculcate these laws, in order that she might soon be capable of controlling her appetites and fancies; and the reAvard Avould be physical strength and beauty. Sensible Avives and mothers are unsur- passed blessings to society; they are the very founda- tions of the happiness of future generations. The external influences of climate, occupations, asso- ciations, and readings should not be undervalued, for truly they have astonishing effects upon the morals and character of the people. A physician practising among young AAromen, no mat- ter Avhat class, should inform himself of the surround- ings that mould the habits and character of his patients. From this source he can gather untold information, Avhich might have a bearing, directly or indirectly, upon the malady; it may even be the very source of the evil. It should be thought necessary to give advice to young women, especially upon the laAvs guiding the 130 PROGRESSIVE MEDICINE. periodical change, and its physical and physiological in' fluence upon the whole organism. The women of the Avorking class are generally occu- pied and kept aloof from any morbid, or imaginary, men- tal troubles. Exempt from idleness, from late hours, from too stimulating food and beverages, which, Avhen constantly indulged in, bring about retrocession of the natural forces and nutrition, this class enjoy generally better health and more physical beauty than their higher born sisters. Happy is the man and Avoman Avhose time does not Aveigh heavily upon their hands (rather say upon their minds). Occupation is the natural and necessary em- ployment of the mental force; it is the healthful stimu- lus of mental activity, and here, asAvith all physical laAvs, action brings about reaction, and a neAV force of physical and organic vigor is the result. The supply is peren- nial: the mental strength increases in vigor during proper employment to a wonderful degree. Action is life, Avithout activity it becomes extinct. The elemen- tary forces are at hand for this grand and great purpose, and if Ave neglect to use them, to appropriate their beneficent agencies, it is our oavii fault if Ave suffer. In justice to many good Avomen of both classes, it must be said that much is done by them daily that is noble, self-denying, and Avorthy of their generous and high conception of the duty devolving on them in the path of life. And to these noble women Ave oavc refinement of man- ners and of feelings, culture, mental and social, and many of the charitable institutions are living monu- ments to their great and good Avork. No social position or Avealth alone can make a true Avoman. Her orna- ments are those of the heart. Nobleness of nature is only shown by noble acts; and a Avoman is only supe- rior to another in proportion to the amount of good she does in her sphere. The attainment of high virtues pro- IDIOSYNCRASIES AND PREDISPOSITION. 131 ceeds simply from a pure, generous, and sincere inspira- tion, the fountain of Avhich is in the heart. Happiness springs from a succession of good actions; mental and moral acquisition, Avithout these true foundations, are mere meaningless names, without an object, Avithout an emotion, hence, Avithout a result. The aesthetic belongs to Avoman as her right. All degrading habits and Adces should be eschewed by the pure heart, Avithout Avhich the fragrance and beauty of gentility cannot be at- tained. Drunkenness or gluttony cause the neglect of those feelings of a nobler nature. " A man's a man for a' that," but never a gentleman, or a gentle lady, Avithout expunging the contaminating influences of indulgences in every phase of life. It is only through a strict accountability of action that Ave can impart mor- ality and individual nobility of character. A noble act is always reAvarded by the consciousness of having done right; a mean, degrading act is punished by an opposite knoAvledge, or that of having done Avrong. Inasmuch as Ave have reached the intellectual quali- ties and social influence, it is to be observed that the training of the mind is as necessary, and as successfully accomplished as that of the body. Strength is imparted only by strict observance of the laAvs regulating both; both are connected by a strong link of relationship un- avoidable, and each reflecting its peculiar influence upon the other. But it is only necessary for the most casual observer to look out upon our great century of progress to be convinced of the gigantic strides of intellectual force. If perseverance and strength of Avill are retained at our command, Ave are capable of as much intellectual as muscular development. And so it is Avith all our links of sociology. Endeavor to do Avell, and cast off the Ioav, degrading, impoA^erishing, destructive elements of vice and neglect, and good will germinate. 132 PROGRESSIVE MEDICINE. The refinement should not only be confined to man- ners and taste, but to thoughts, aspirations, and feel- ings. Educate the mind and the heart. Surely good qualities, like everything else that is good, spring from its elements or nature, but that good, Avell employed, can be increased to an inconceivable degree. Our chain of thought has not parted from the anchor, which holds still to the subject of force and develop- ment. The mental are not separate from the physical laws; and Avhat is the rule Avith the latter is also Avith the former. Returning to our first proposition; Ave have surely seen the effects of labor, and proper regulations of life compared with those Avhose good fortune cast them silver and gold, but Avhose misunderstanding of life develops only elements conducive to disintegration, physical and social. The conclusion is noAV reached by actual demonstra- tion, namely: action brings back force and life; activ- ity of mind and body develop to a Avonderful degree their resources and strength; health of body, of mind, and of thought depend upon many agencies—1. The true interpretation of nature's Avants. 2. Adherence strictly thereto. The endoAvments of these tAvo classes of women must depend upon their amount of physical force. They must acquire this before they are able to undertake mental or physical labor; and this is only done by ex- ercise, gymnastic or otherAvise, and employment of the mind, Avhich is mental exercise. These are tAvo health- ful and indispensable principles. Then heat, light, diet, etc. In these lies the great fountain of life. The young ladies should rise early, walk, and breakfast early. Then mental or domestic employment should be their choice. At this very point Ave see clearly the connec- tion between physical and mental exercise or labor. IDIOSYNCRASIES AND PREDISPOSITION. 133 And if this is not done, inertia, retrogression, and decay are the results. It is needless to repeat here that from the act of de- composition that life and force spring forAvard Avhich are lying dormant in matter, put there by the great Providential Entity; and that this can only be accom- plished by applying the proper agencies. And Avhen life has made its appearance Ave must sus- tain it, repair it, and increase it by the same law. The equilibrium of this great principle is found in properly understanding the method of action and reaction. Is a young girldeA'oted to study and retirement? She needs physical action to bring back vital force. Does a la- boring Avoman Avork too hard? She needs rest, for the physical Avaste is too great in proportion to the repair. The tAvo opposite and yet parallel cases of gaining or getting Avhat is necessary to life are plainly visible to every one. The axioni is indisputable. The great remedy lies in teaching these fundamental Liavs; to cure evil Ave must understand from Avhat it arises, and how it is to be avoided. 134 PROGRESSIVE MEDICINE. CHAPTER II. PROXIMATE CAUSES OP MAL-NUTRITION. Almost every organ may produce a change in the di- gestive apparatus by sympathy and reflex action. And so, vice-versa, the functions of digestion being impaired the general system must suffer, and those organs Avhose physiological relations are correlated and closely connect- ed Avith the functions of organization, are the first and the more predisposed to be affected, i. e. the stomach, the liver, the heart, and the kidneys. The influence of the mind upon the process of organization through the ner- vous system is obvious. It is not intended to take up psychology, but merely to endeavor to demonstrate the great variety of causes Avhich are capable of being, and may often be direct causes of adynamia, from Avant of the proper agencies of nutrition. It is therefore well, that Ave should be very particular in making differential diagnoses betAveen cause and effect: or betAveen idiopathic per se, as entirely discon- nected Avith any other organic reflex influence. This does not discourage symptomatology in the least, on the contrary; Ave must be very careful in distinguishing primary from secondary symptoms; the pathognomonic from the subordinate and sympathetic symptoms. And in this Avay alone can Ave take the picture, and receive and study the impressions so as to form a true concep- tion of it. It cannot be denied that symptomatology, even with all its present imperfections, is one of the brightest jewels in the laAv of Similia. PROXIMATE CA USES OF MAL-NUTRITION. 135 The structural part of the brain is too well knoAvn to require any anatomical description. Its spongy, tubular filamentous and cellular arrangement is all included in the Avhite and gray matter—the former the sensory, the latter the motory, and from the unity of these too, there is a further arrangement, a great provision made, namely the ganglionic system. This beautiful distri- bution of forces is indeed most providential, for the or- ganic functions must be intimately related Aviththe ner- vous system as their demand is continuous and the supply must be near and abundant. It appears, therefore, that the sympathetic system is endowed Avith both sensation and motion (vasa motor). These electric and magnetic forces are concentrated in the knots that supply the Avires of nervous filaments with the requirements for their Avork. This blending of the tAvo forces in the ganglia is a happy provision, thus preventing any jarring, and at the same time giv- ing to the system a uniformity of action indispensable to physical and organic functions. Each spongiole is endoAved Avith a peculiar and com- plex function. Every cell acts through the vivifying influence of the dynamic forces, and these are elementary—light, heat, motion, and nutrition. The great centre mustreceiA^e a sufficient quantity of the vitalizing principles to enable it to supply its ganglia, the organs of special sense, and the muscular system, Avith nervous fluid and blood. Every cell must move and receive nutrition and ra- diate force, activity, and life. It is a rotary, physical motion; receiving and giving, equilibrated harmoni- ously, so that the action is smooth, imperceptible, and perfect. (Co-ordination of forces.) And is it surprising that so many are Avanting in men- tal vigor and health? The difficulty of maintaining an equilibrium among so many physical requirements is an obvious reason for the deficiencies Avhich so frequently 136 PROGRESSIVE MEDICINE. occur. The influences of climate, idiosyncrasies, inheri- tance, predispositions, occupation, social surroundings, and education are so many strains upon the great ner- vous centre. Illusions, hallucinations, delusions, men- tal aberrations, lunacy—these mental deflections from the normal functions are often present in a greater or less degree, and are either idiopathic or symptomatic. CLINICAL CASE I. A young lady, tAventy years old, of a nervo-lymphatic temperament, having indulged in all sorts of vagaries from her childhood to the present time. A feAv years ago she entered a female school. She Avas always very delicate and excitable. She had complained of shortness of breath, slight cough, pain in the left side and constantly feeling ex- hausted or Aveak and trembling. Her medical attendant Avas puzzled, and held several consultations without much benefit to the patient. I Avas requested, just about a year ago (June 15th, 1877), to go as a consulting physician to the patient, whom I found in a most miserable condition, both physi- cally and mentally. Physical Signs.—On percussion there Avas no dullness. On oral examination I found no crepitant or sibilant rales. Respiration short, expiration prolonged. No vesicular or labored respiration. Temperature rather high over the lungs (99-200 and a fraction.) Heart per- fectly sound, organically and functionally; no valvular deposit or enlargement. I could find no abnormalities. Uterus sensitive. Had vaginal leucorrhea. Kidneys sound—urine profuse and Avhite. Liver torpid. Night SAveats. Mentally, she seemed a sensible girl, Avith the usual excitable temperament, but ATery taciturn. Very thin. Semiology.—She looked emaciated, anaemic and ady- PROXIMATE CAUSES OF MALNUTRITION. 137 naemic. She had no appetite, but was not distressed by food Avhen taken—constipation. Her countenance de- noted great exhaustion from inanition. Pulse very much enfeebled in volume and irritable in action, and small and thread-like. Flesh hot moist and very white; capillary veins full. She Avas very impressionable and easily affected. She sighed and moaned and looked hysterical. Hyperaesthesis was very great. Complained of pain on the left side, and had a constant, dry, hack- ing cough. Insomnia, apepsia and irregularity of menses. She had been sick for months and thought herself dangerously ill. Hid been confined to her bed for over tAvo months and could not Avalk across the room. She Avas indulged in every fancy. She had no vitality and no force of will. She Avas completely discouraged and abandoned her- self to notions and despair. I could not find any hered- itary trouble, for her father and mother Avere healthy, strong and Avell-to-do people. Etiology.—I could not find any organic disease, struc- tural or functional; there Avas general torpidity of the functions of organic life, consequently the organs were under a general physical debility. I dated her illness shortly after the time she entered school. Her retirement to close quarters after having been accustomed to fresh air and exercise had something of an influence over her. Her companions might have predisposed her to romantic notions, fanciful love and unsatisfied desires. The uterine functions Avere suspended on account of the general debility, and nutrition Avas similarly im- paired. Her Avhole character and idiosyncrasies Avere those of a hysterical girl, her disease existing in the emotional or ganglionic system. There was no indica- cation of disease of the absorbents. The mental force had lost its equilibrium and its vigor. Her mind Avas morbidly predisposed and although 138 PROGRESSIVE MEDICINE. she Avas not a lunatic she Avas next door to it, partly through indulgence on the part of her family. And in summing up the objective and subjective symptoms Ave find no lesion, but a general disability, a curious phe- nomenon of abnormal condition, and, in my judgment, referable to mental, emotional and uterine influences. My prognosis Avas unfavorable because of the state of enervation and hyperaesthesis Avith a Avant of the Avill and disposition to succumb to morbid notions. Hygiene and Dietetics.—Cold Avater shoAver-baths Avith salt. The idea Avas to re-establish equilibrium of forces, physical and vital, by a shock, and a number of them continued every other day. If that should be too severe Ave Avould try sheets and sponging. Air, light, cheerful company, encouraging her to leave the bed and room. Diet—Beef-tea, cream, clams, mutton, birds, fish, rice, oat-meal, eggs, lettuce, cocoa, Avine Avhey, or ale. I forbade potatoes, corn, pies, candies, coffee and tea. Early rising and early retiring. In this I included change of locality and driving out. Medical Treatment.—Nutrition here Avas an alterna- tive of great importance, for she could not get enough food and nutrition to sustain the economy. Since I arrived at the conclusion that it Avas purely a case of adynaemia, I certainly had but to act upon that de- cision. It Avas necessary to restore as much of the subordi- nate and indirect symptoms as the primary, for they Avere derived from the same origin. Her hyperaesthesis was a natural consequence, but a stumbling stone to carry out certain medical treatment, to restore calmness in place of irritability. The folloAv- ing Avas my first prescription as preparatory to a more specific one: #. L 'ctucaria, 1-dec. gutt. xxx. Aqua distill., ? iii. PROXIMATE CA USES OF MAL-NUTRITION. 139 Dose—One teaspoonful every hour till quiet and sleep were produced, folloAved by strong acidulated drinks, and beef-tea. In a feAv da}'s she gave signs of improvement, by sleeping better; cough was better and had gained strength and cheerfulness. Then I recommended to her attendant physician to give her #. Phosphorus, 6-dec. gutt. xii. Aqua distill., ^ ii. The doctor reported improvement in every respect; in a few Aveeks she left her room and Avent out. For some reason the improvement did not continue and she Avent back to her former condition. I believe that her medical attendant Avas not persevering enough and that she indulged again in her favorite diet of pies and candies, and did not keep up a strict hygienic and die- tetic regimen. CLINICAL CASE II. A maiden lady, sixty-five years old, of nervo-bilious temperament. She Avas an only child, and therefore very much indulged and spoiled. Her life had been that of comfort and indulgence. Her family Avere Ave al thy and disposed to enjoy the good things of the Avorld. They Ave re highly cultivated people, and this good lady had inherited a sensitive organization and in- creased it by her peculiar training. She had met Avith many a sorroAV and disappointment, inconsequence of Avhich she became morbid and con- stantly given to despondency. After the death of her parents she became an hypochondriac and closed herself in the house for a long time giving admittance to no one —even her dearest friends. Physical Signs.—There Avere no indications of structural organic troubles. Lungs sound. Heart perceptibly ex- cited by nervous influences. Liver rather large and tor- pid. Stomach sensitive. Kidneys healthy. Temperature 140 PROGRESSIVE MEDICINE. normal. Pulse small and quick. Well developed; rather stout. Light eyes and complexion. Small frame. Subject to borborygmus, acidity and constipation, alter- nating with diarrhoea. I found her reclining on a chair Avith her feet on the bed—one of her legs being shorter than the other. Semiology.—I Avas called to see her in regard to an injury she had received months previous, having broken the patella by a fall on the ice. She Avas treated for a transA7erse fracture of the intertrocanteric line of the femor, Avhich Avas a mistake. HoAvever, she complained of inability to stand, Avith pain in the knee joint. As union had taken place there Avas nothing to be done as to her former surgical case. She might have had an impacted fracture of the head of the femor, intercapsu- lar of cause, with a fracture of the patella. But the perfect motion of the head, Avhich she ahvays had, did not denote any such injury. The shortening Avas due to retraction of the biceps femoris and ankilosis of the knee joint. I found her despondent and hopeless ef being able to Avalk again. She related to me some of her great sor- roAvs, amongst Avhich, besides the loss of friends, there Avas loss of property. She told me in the most touch- ing manner of her lonely life: of having lost all her re- lations and from affluence, beauty, social position and brilliant company, she was reduced to comparatively scanty means amongst strangers. There Avere indica- tions of mental troubles. She Avas excessively irritable, Avept easily and became uncontrollably angry at trifles. She suffered indigestion and biliary accumulations with acidities in the primae vie which altogether produced flatulency, bitterish, sour eructations—borborrygmus and at times bilious colic. She Avas anaemic and asthenic, but had vital force enough to supply a regiment of men. Yet she was coAvardly as to pain. She Avas very im- aginative and suspicious. Capricious and constantlv PROXIMA TE CA USES OF MALN U TUITION. 141 changeable. Nothing could ever suit her longer than a a day or two. Constantly complaining though at times very cheerful and amusing. Hysterical. She could have felt pain in her little toe, if she only thought so. These seeming light symptoms are of great importance to us, so as to locate the origin of the trouble. The process of digestion Avas generally good, considering that she Avas devoid of motion, air, and mental activity, thus the phenomenon of the functions of organization Avas partly imperfect. In point of fact, she had a small way for the process of decomposition, and, hence reaction could but be cur- tailed, physico-vital forces diminished to a great degree. The pabulum vitae Avas slowly decreasing as the pro- cess of organization and re-vitalizing principles Avere so much decreased. The palpitation of the heart was due to a sympathetic influence, either from the stomach or from mental hallucinations. She Avas a great sleeper and there Avas much in that that recuperated her enfeebled economy. And Avhile at this point let me say that, physicians should pay attention to rest as a principle of cure in cases of enervation. And the rest must be complete, for Aveeks at a time, Avith a Avell selected diet and bathing. Etiology.—Predisposing causes Avere, inheritance, edu- cation, and enervating habits. Excitement, indulgence, mental troubles, and Avant of physical motion and men- tal employment. The principal part affected was the ganglionic system. Treatment.—She had been Avell directed in regard to hygiene and diet. The only medical treatment Avas by means of electro-magnetism. And although the ankilosis was much benefited as well as her general system, jet she set her will against any possibility of cure, so that I could never persuade her to leave her position or room; and she Avas fully able to go out in a carriage. I learn- ed that the force of the will had much to do with her condition. The treatment Avas unsuccessful. 142 PROGRESSIVE MEDICINE. CLINICAL CASE III. A Avoman forty-five years old had been frequently sick and Avas well knoAvn as an invalid. She Avas well de- veloped, of a nervo lymphatic, or leuco phlegmatic tem- perament. She had two children and Avas surrounded Avith sufficient comforts for her station in life. A wo- man of light complexion, blue eyes, and a large, portly frame. There Avas no appearance of any constitutional disease. Her physician asked me in consultation, as he thought the case very serious indeed; I found her confined to her bed. Semiology.—As the patient did not complain, but of general sickness, Avithout pointing to any special organ the examination was superficial, and not as thorough as I might have liked; however enough Avas ascertained, to shoAv that she had an ulceration of the neck of the uterus and uterine leucorrhea. AfterAvards I ascer- tained the ulceration by physical examination. I found her in a room all closed, and there Avas an air of the mysterious Avhich struck me as the sublime of the ridiculous. Her medical attendant Avas thoroughly de- ceived by these fanciful appearances and cautioned me to keep very quiet. In truth, there Avas a consummate piece of acting going on, and I made up my mind that Ave had a fine case of hysteria. Her attitude, the clos- ing and shutting of the eyelids, the long sighing and her insomnia, denoted an hysterical condition, with hyperesthesia of the organs of generation. After he asked how she Avas, she took a long sigh and answered, " Oh Doctor! I Avas very sick all last night. I believe I would have died, if it had not been for your medicine." Her general appearance Avas that of a person who had not suffered much physically. When my turn came, I asked her to open her eyes and to shoAv me her tongue, in a civil but firm manner. Eyes Avere clear, and tongue white and tremulous. Pulse small PROXIMATE CAUSES OF MAL-NUTRITION. 143 and sIoav, indicating a Avant of force and volume. Urine very Avhite and copious, specific gravity natural. She complained of palpitation and distress in the stomach. Food did not digest easily and she ate very little. Temperature Ioav and general debility, indicating sorneAvhat asthma. There Avere no complications of the liver, and her boAvels Avere regular, Avhen not confined to her bed. Mentally she Avas afflicted Avith all sorts of hallucina- tions. She suffered Avith uterine and vaginal leucorrhcea proceeding from ulceration, general debility, arising from her phlegmatic temperament. There Avas great flatulency and sensibility in the ovarian regions. At times she Avas cold and chilly. Aphomia Avith a feeling of suffocation. She imagined herself a great inAralid and thought that she Avas going to die. She spoke in a whisper and kept the room very dark. She had paroxysms of fainting, Avhich frightened every- body present; but the faint Avould disappear and leave no trace of any physical trouble. She imagined every body Avas talking about her and her recurring sickness. . Etiology.—This Avoman had been sick more or less for years, and indeed proved to be a great trial to her poor husband and friends. Such cases are rather rare in the loAver path of life. Hard work and practical knoAvledge of the difficulties and troubles of life keep many a Avoman from becoming hysterical and morbid. I was rather perplexed to find out the cause of this condition of things on account of her sphere in life. Her marriage to an indulgent and good husband brought about affectations and deceptions too numerous to mention. A firm, strong Avill on his part; or a sense of honor and duty on hers Avould have savTed them a small fortune. As her physician left the place, she came under my care for medical treatment. The dis- 144 PROGRESSIVE MEDICINE. ease Avas hysterical and located in the ganglionic sys- tem. She cried easily, and Avould be taken sick at a moment's notice. Her idiosyncrasy was a tendency to ovaritis and uterine catarrh. Hygiene and Dietetics—As indolence was one of her characteristics, I advised her to do her own Avashing and house-work without hiring a Avoman to do it for her. She was ordered Avalking in the open air and warm bathing. Diet: good meats and bread, leaving aside the pies and hot bread, etc. Medical Treatment.—I took it upon myself to advise her poor husband, but I found him too weak for such an undertaking. Nothing but a firm, kind, unflinching Avill could con- trol and really cure such morbid phenomena: #. Belladonna 3-dec gutt. xii. Aqua distill. fo iv. Dose—one teaspoonfnl every 2 hours. She got bet- ter for a feAv Aveeks, but became sick again. I called upon her, found her in the same condition, and gave her the folloAving remedies. Pulsatilla, ig- natia, changing every Aveek, although I had no idea of curing her. A great misfortune, the death of her hus- band, took place tAvo years after I kneAv her, and this added to poverty and a sense of the injury she had done him, cured her completely of all her vagaries. This will serve as an example of the many disarrange- ments of the digestive organs produced by morbid no- tions ; and, Avhat is very strange to find, such a perfect case of misanthropy in a Avoman in her condition of life. Had she been a lady born in affluence she could not have presented a better case of hysteria produced by the imagination. Plenty of Avork, good principles, instilled early in life, and a stern, just, and conscientious husband will cure most cases of hysteria. The ulceration and hysteria were treated locally by nitrate of silver, and by PROXIMATE CAUSES OF MALNUTRITION. 145 Tjc. Nux moscata 1-dec 31. M. chart, xxx also 9. Borax 3-dec 3L M. Chart, xxx #. Sepia 3-dec 3U M. Chart, xxx. £L Moschus 3-dec gutt. xii. Aqua distill., f iv. These Avere given during three Aveeks' attendance. She improved and got better, although she had recurring attacks. CLINICAL CASE IV. A young Avoman, tAventy years old, of a bilio-nervous diathesis, dark skin, black hair and eyes, and hand- somely developed. She Avas the mistress of a gentle- man, and lived a life of ease and comfort, if such can be found in degradation and vice. When I made my first visit she Avas considered very ill indeed. Physical Examination.—I found her in a state of un- consciousness. Pale and utterly lifeless. SIoav breath- ing. Pulse very small in volume and slow in action, indicating a partial suspension of the influence of the vaso-motor nerves. Urine she passed in bed. No or- ganic trouble of the heart or lungs could be found. Liver normal. Pupil contracted. Tongue could not be examined as her mouth Avas firmly closed. She had clonic spasms, Avhen she screamed, fought and rubbed and tore herself, unless kept from it by main force. She Avas totally unconscious. Semiology.—She complained before she Avas sick of malaise, general debility and Avant of appetite. She Avas found Aveeping, angry, unreasonable, and excited. This Avould pass off, to return again in a feAv days. She had chills and headache and great nausea. She became suspicious of her lover, and feared that he Avould soon leave her; then she would refuse eating, and fainting 146 PROGRESSIVE MEDICINE. would occur. Her peculiar position in life, her dissipa- tions, and -mental and emotional excitement, predis- posed her to nervous diseases. There Avere difficulties in making out a correct diagnosis, oAving to the resem- blance of malarious poison or of uremic metastasis. She did not improve for several days; therefore I thought it necessary to have a consultation. The consulting gentleman saAv at once in it a case of malarious poison from the malarious district of Nor- folk, Va. I did not agree Avith him, yet I followed his advice. We gave her quinine in large doses, because he thought her life Avas in peril, and because Ave both belonged to the rational school, and must treat the case secundum artem, happen Avhat may. In tAventy-four hours she Avas Avorse, and had not eaten anything for nearly a Aveek. Adynaemia Avas threatening. I consid- ered it my duty to call the attention of my colleague to the pathognomonic symptoms of irritation of the vulva and the partial suspension of animation, and the internal contractile condition of every fibre, and the wonderful phenomenon of life without alimentation. I therefore concluded that those few salient points were the beacon lights of unusually intensified and hysterical conditions. He immediately assented to my opinion and changed our treatment accordingly. Etiology.—She had lost her virtue early in life, and had been exposed to seditions, temptations, and vices ever since. Her nervo diathesis and bilious tempera- ment predisposed her to Ariolent paroxysms of excite- ment, and her diseases Avere mainly of a nervous char- acter. Her over-indulgence in sexual pleasures debili- tated her, and Avas an exciting cause of her sensitive temperament. In connection Avith this, Ave must not forget the food and drinks, Avhich such people indulge in at late hours of the night. In conclusion, her Avhole tenor of life Avas debilitating, corrupting, and disorgan- izing. No Avonder that her system became the prey of PROXIMATE CAUSES OF MALNUTRITION. 147 hyperaesthenia, enervation and exhaustion. The uterus and ovaries were peculiarly in a state of excitability, and hence hysteria. These numerous evils brought about a reflex action to the spinal nerves, medula, and brain. Mediccd Treatment.—I suggested an enema of assa- fcetida and a little Castile soap—about tAvo ounces. The injection Avas retained, and after a feAv hours she opened her eyes and spoke to the attendants, asking them Avhat had occurred. She had knoAvn nothing for tAvo Aveeks. She took three injections during twenty-four hours, and beef tea, Avhich she digested perfectly. She slept a good deal, and gave signs of twitching during her sleep, but Avould Avake up, take her nourishment, and then go to sleep again. Her Avhole system Avas not only exhausted, but gave evidence of anaemia. On the third day Ave used belladonna and hyosciainus, and in a Aveek's time she was up and about, although very feeble and nervous. Hygiene and Dietetic.—Warm bathing every night, Avith salt, hard bed, no company, and a drive out in the open air. Her alimentation Avas composed of cocoa, cream, eggs, oatmeal, and fruits for breakfast. Dinner —roast beef, generous Avine soup, mutton, chicken, and sago. Evening—cream and biscuits. She was removed into the country, where the quiet and pure air did the rest of the cure. 148 PROGRESSIVE MEDICINE. CHAPTER III. GERMINATING MALARIOUS ORGANISMS AS DEVITALIZING AND DISORGANIZING CAUSES OF THE FUNCTIONS OF ORGANIC LIFE. Unquestionably any floating molecules arising from a process of fermentation and decomposition contain- ing a living germ, and a force of development, as soon as they touch a fertile soil, like the human economy, the vegetative process begins at once, and proliferation extends to an unlimited degree. They reproduce their oAvn kind: be it torula from the vegetable ferment, or azone from animal decompo- sition ; both are virulent, mephitic, infectious influences, often in the form of a vapor or gas. There are A-egetable decompositions Avhose ferment disseminate carboretted hydrogen gas, and others, sul- phureted, Avith pestilential effects. The animal decomposition Avhose ferment is azone, nitrogenous gas, or ammoniated substances, produce a variety of diseases differing from the vegetable kind. From the typhus and typhoid to the bilious, gastric fever; from the simple intermittent to the congestive pernicious fever; from light digestive difficulties to the utter disorganization of the process of chylification and nutrition. All kinds and all forms of ailments may proceed from such morbific influences, yet the origin be the same. Dyspepsia, hepatic troubles, splenic, enteric, renal, nervous scrofulous, eruptive zymotic. Every variety of physical change is possible in malarious infections. Neuralgia, asthenia, metastasis, catarrhal, pulmonary, DISEASES FROM IMPERFECT NUTRITION. 149 uterine diseases, mal-assimilation and nutrition Avith leucothemia and adynaemia. Many are the ravages of these morbific floating germs, and Ave have just had the experience of the un- fortunate South in the form of yelloAv fever. The Pon- tine marshes near Rome and the valley of Lombardy are sources of as virulent effluvial exhalations that can be found. The rice fields of Lombardy or the Carolinas predispose people to the most disorganizing diseases. Also excessive temperature and moisture produce mor- bid gases and dissolution of the animal economy. The eruptive diseases are often the results of climeric influences—erysipelas, scarlet fevers, small pox, measles, eczema, etc., as also choleraic and cholera, diarrhoeas anpl dysentery either connected Avith gastro-hepatic trouble or idiopathic. Even the hardihood of the peas- antry has, sooner or later, to succumb to these morbific influences In those localities on the continent, Avhere this efflu- via prevails, Ave find that the people suffer more or less, at certain times of the year, and Avhen the Aveather is favorable to these exhalations, from many forms of dis- eases of the nervous system, the lymphatics and chylo- poietic viscera. A good climate, containing exhilarating oxygen and good Avater, Avith the genial atmosphere of a temperate nature is productive of longevity, cheerfulness and health; all these are derived from air, light, motion, electricity and heat: People strive to acquire Avealth too quickly, and in their haste consume their energies, their happiness, and even their liATes. Hoav much bet- ter if they should seek a genial climate Avhere the ele- ments are superlatively conducive to health and com- forts. Elementary changes and loss of their equilibrium brings about the most depressing, devitalizing and dis- organizing consequences. Paleness and cachexia are stamped upon the faces of 150 PROGRESSIVE MEDICINE. the people who live in malarious districts. They are proverbially melancholic, losing the cheerful part of lile, and a shadoAV of gloom overhangs their whole existence. The gastro-hepatio and intestinal secretions become changed and give at once the alarm. During the war of the rebellion the diseases of the alimentary canal Avere perfectly fearful, decimating the army. (Lieu- teria). The rank and file Avere all attacked alike. We Avere all subject to the same depressing and devitalizing climatic influences and had to suffer similarly. Tavo great and different physical changes took place in the liver suppression and retention of the bile. The mal-assimilated food brings about an acidulous contami- nation in the secretions, and hence in the blood. The bile being an element extracted from the venous blood Avas naturally abnormal: Avhat could be expected but crude biliary secretions. And more: Avhen physical force has become much impaired, the functions of organic life and vitality becomes likeAvise crippled and loAvered, and the organization is imperfect. In one case there may be retention from obstruction; in the other suppression from organic difficulty either functional or structural. There are degrees in deseases of more or less intensity. All this may be simply hepatic, or combined with trouble in the alimentary canal. It may be primary idiopathic, or secondary and symptomatic from the digestive organs. In effluvial diseases the Avhole gastro-hepatic and en- teric canal is generally affected. Again the spleen be- comes emrolved and then Ave find in the morbid ana- tomy an increase of the Avhite corpuscles in the spleen as Avell as in the general circulation. The blood there- fore is deteriorated and the results are Avell knoAvn. CLINICAL CASE I. During the Crimean War Ave learned Iioav very limited Avere the good results from the rational school of medi- DISEASES FROM IMPERFECT NUTRITION. 151 cine, and hoAV many thousand died of a Ioav form of lien- teria or fevers. During the American Avar of the rebellion, in Avhich I Avas an officer, the same diseases prevailed among the soldiers, and thousands died of dysentery, diarrhoeas, and chicahominy fever—a species of typhoid abdomin- alis. The records shoAv the mortality of the American Army during that Avar and the utter incompetency of the Ra- tional School to compete Avith diseases arising from morbific gases. I shall not attempt to say Avhat the laAv of similarity Avould have done, but I feel sure, that many a true allo- path Avill agree Avith me, that great mischief and actual harm Avas done by the routine practice of medical of- ficers in the field. They used indiscriminately and most empirically about four favorite compounds, and this Avas done in the face of the Avell knoAvn failures of such a treatment. And these Avere the folloAving— p. Comp. Cathart. pills. U. S. P. $. Camph. et. opii U. S. P. #. Blue mass. #. Quinia sulph. #. Anti- mony. #. Tincture catechu et creta pr. $. Acid Tan- nic et chinchona etc. I shall forbear to make any com- ments upon this rational proceeding. Physical Examination.--Mrs. K., tAventy-seven years of age, a German Avoman—has one child. She was confined to her bed. On examination I found her very anaemic. Heart made a sound like that of a belloAvs Aveak and irritable. Pulse small and quick. Temperature Ioav Avith a moist skin, inclined to Aveakening perspiration. Emaciation, exhaustion, respiration short and quick, but no disease iiiA-olving the lungs could be discovered. Liver enlarged with constipation of the boAvels. Tympanitis, and dropsical effusion of the loAver extremities. Semiology .—She complained of chilliness every after- noon from three o'clock until five, pyrexia, the head and 152 PROGRESSIVE MEDICINE. face Avere hot and then a free, hot perspiration complet- ed the crisis. There Avere regular intermissions and the signs Avere those of an intermittent form of feArer. She Avas taken soon after the birth of her child and it affected her Avhole economy most unfavorably, being at the time, enfeebled by the process of parturition, the loss of blood, and all its concomitants. The uterus Avas enlarged and tender on touch. As- thenia and adynaemia Avere depicted upon every fea- ture. She lived in a small house, situated on low ground and surrounded part of the spring and fall seasons by water. They lived on greasy, innutritious and indi- gestible German diet. The process of chylification was defective. She Avas well-formed and young, but her life Avas gradually ebbing aAvay. The urine Avas of Ioav specific gravity. Pupils rather large and lifeless. Etiology.—Naturally Ave Avould conclude that malaria Avas the main spring of the disease, yet there are other considerations Avhich are of absolute necessity to observe. 1. Her mode of living being unhealthy and innutritious; 2. Change of climate from her native country to a debilitating malarious spot in this country. 3. Mental troubles on account of her destitution; 4. Stagnant Avater producing an effluvial atmosphere; 5. Wantof knoAvledge even of the first principle of common cleanliness. No wonder that disorganization, physical and vital, Avere fast ending her life. Hygiene and Diet.—1st. Removal from the Ioav marshy place Avhere she Avas in to a high sandy soil. 2d. Bath- ing in alcoholic baths. She Avas too weak to use the Avet sheet. 3d. Hard bed and airy, clean room. Diet.— Nitrogenous, with brandy and Avater, after meals. Medical Treatment.— #. Ars. Solution, 3 dec. gutt. xxiv. Aqua distill., f ii. DISEASES FROM IMPERFECT NUTRITION. 153 Dose—one teaspoonful every hour during the inter- mission. This Avas purposely given so as to break the paroxysm of the pyrexia and the chills, which together Avith the hygiene and diet succeeded admirably. I folloAved by $. Ferrum phosphatis 3-dec grs., xxxvi. M. Chart, xvi. Dose—one poAvder every three hours. I continued the diet. The progress of the disease Avas checked and a change in the quality of the iron Avas advisable. #. Ferrum Peroxidum 1 dec gr., xl. M. chart xxx. Dose—one poAvder four times a day. In the course of tAvo months the woman Avas Avell. CLINICAL CASE II. A young girl of nineteen summers, perfectly healthy, became suddenly affected Avith facial paralysis. She did not give the usual signs of neurosis either from anaemia or toxymia, nevertheless she Avoke up one morning Avith a crooked mouth. Physical Examination.—Pupil normal. No pain in the spinal column on percussion. Locomotion perfect. Digestive organs in a healthy condition. Heart and lungs sound. And Avith all these favorable signs she was emaciated, anaemic and extraordinarily weak. Something Avas destroying the nervous force and the blood. She digested food but did not assimilate it. There Avas a sort of mechanical function going on Avithout the poAver of organization. Semiology.—There is a negative diagnosis Avhich is often as important as the symptoms usually traced out. The absence of neuro-phlogosis objectively was remark- able—no pain, no heat, no swelling; only distortion. There Avas a tonic contraction of the muscles of the face caused by an affection of the fifth pair of nerves. On further examination it Avas found that perfect an- asthesia of the Avhole left side of the face existed. No 154 PROGRESSIVE MEDICINE. further trouble took place; it Avas confined to the face. Etioloyy.—The cause Avas traced to night exposure in the malarious regions of Jersey City. Hygiene and Diet.—Removal from Jersey City for a feAv weeks into the country. Bathing in Avarm salted Avater every night. Nitrogenous food and good port Avine at dinner. Medical Treatment.—Electro-magnetic current was passed over the medulla oblongata and branches of the fifth pair. In four Aveeks she Avas well. She took #. Nux vom: 3-dec ten pellets every four hours. The idea that miasmatic and infectious poisons pro- duce a great number of different maladies is correct. And this is according to experience and science. The vital force is suddenly struck doAvn before the phy- sical force and functions are affected. These efflu- vial poisons demolish, as it Avere, the correlation of the animal economy. When these exhalations are of a mild degree of morbidity there are lighter forms of dis- eases. Moisture and carburated hydrogen produce catarrhal affections, bronchitis, conjunctivitis, catarrhal pneumonia, phlegmasie of the bladder and kidneys and the like. CLINICAL CASES III-IV. Not long ago I Avas sent for to see a gentleman forty- five years old, and his son of about nineteen. Both Avere suffering intensely from gastro-enteric troubles. They were recent cases, and the result of night expo- sure. Physical Examinations.—The stomach and abdomen Ave re inflated, and both tender to the touch. Urine scanty and deep yelloAv. Emesis troubled them fre- quently, and the properties of the matter ejected Avere Avatery, sour and bitter. Evidently it contained gastric and biliary substances. The faeces contained carbur- eted hydrogen, and at times Averc very fetid, indicating DISEASES FROM IMPERFECT NUTRITION. 155 a change into a sulphurated or nitrogenous undigested matter. The bile Avas retained, hence the abnormal faeces. Semiology.—Although both had nausea, a feeling of distress and emptiness in the stomach, Avith pain in the small intestines, and gas, the father's symptoms Avere more intensified. He had a febricula, great exhaus- tion, and pyrexia of the cerebrum. The son had no fever, no pyrexia cerebralis, and not even the same gas- tric exhaustive feeling. They could eat nothing, although they had a desire for food. They Avere very Aveak; and the tongue Avas slimy, and yelloAvish in the centre. Tympanitis, bor- borygmus, and pain. DroAvsiness; face pale, and eyes denoting general debility. They had from four to six passages of Avatery dirty faeces every three hours. During the intermissions they felt no better, and ex- perienced no relief from the evacuations. Etiology.—They Avere exposed to a south-east Avind, full of moisture and nitrogen, and to exhalations from a Avet, spongy soil, Avith a growing vegetation. It struck them in the gastro-enteric regions, and the consequence was just Avhat is described above. Had the vegetation been on its decline, the vegetable decay Avould haAre added much more poison to the air, and both or one of them might ha\re had typhus or typhoid fever. Had it been a paludal soil, instead of the rocky, the alluvial malaria Avould have struck them down Avith gastro- enteric fever, typhoid, pernicious, or intermittent fever. Hygiene and Diet.—I ordered a small Avood fire in the house, complete rest, etc. Diet—beef tea, a small quan- tity of solid food, and burnt brandy, Avith toast. Rice, and rice Avater to drink. Medical Treatment.— R. Ipecac. 3-dec. grs. xxx or sj. M. chart, xv. R. Mercurius alkalizat. 3-dec. grs. xxx or sj. M. chart, xv. 156 PROGRESSIVE MEDICINE. Dose—One poAvder every tAvo hours each. They improved to a certain extent; they had, at longer intervals, hoAvever, the same copious choleraic evacuations, Avith nausea. On the second day I ordered to the son— #. Podophylum, 3-dec. grs. xxx. Dose—M. chart. XAr. #. Lycopodium, 3-dec. gutt. xii. Aqua distill, f ii. Dose—One teaspoonful every hour during the day, alternately Avith the powders. To the father I prescribed otherAvise, for he had someAvhat different symptoms. p. Byronia alba, 3-dec. 3 ii. (vial). —In pellets. Dose—Six pellets every hour. #. Mercur. alkal., 3-dec. 3 sj or xxx. M. chart, xx. Dose—One poAvder every hour alternately with pel- lets. On the fourth day I gave them R\ Camphor, 3-dec. pellets 3 ii. (vial). Dose—Ten pellets every hour or tAvo accordingly. I must remark here that the given podophylum to the young man had the desired effect, i. e., it decreased the evacuations and increased the biliary secretions so that he Avas free from borborygmus and pain. It Avas truly homoeopathic in its pathogenesis and quantity. (See symptoms.) In the case of the old gentleman I finished the treat- ment Avith nux vomica and arsenic in order to relieve the great depression of the gastric nen*e and change the enteric trouble. The, feeling of a distressing empti- ness Avas unmistakably caused by nervous exhaustion. It is Avell knoAvn that exhalations have some pathogno- monic characteristics according to the nature of the gas afloat. The often used terms " malaria" and " infection" DISEASES FROM IMPERFECT NUTRITION. 157 are synonymous Avhen applied to a condition of a poi- sonous atmosphere. A damp, cloudy air will chill the body by absorbing the heat from it. Hot, dry air excites pyrexia and phlogosis, either general or local, objective or sub- jective. But the hot, moist air has the most depressing and destructive influences of all. From the latter Ave have hepatic, abdominal, and Ioav forms of disease of a pernicious, malignant type. It favors yelloAv fever. In India and South America the most malignant forms of disease exist, e. g\, yellow fever, cholera, small pox, and other zymotic diseases. The contrary is to be found in Russia and Japan: there the diseases have a tendency to disorganize by the sIoav asthenic process. The same in Scotland, England, the Loav Countries, etc. In contradiction to this Ave observe very different effects from mountainous, cold, dry air Avhere the oxygen abounds and the depressing carboniferous elements are at the minimum. The study of climatology is an indispensable item to all physicians; for the knoAvledge of the peculiarities of certain climates give us the key to many causes of the diseases existing. From this knowledge Ave learn Avhether Ave live in a stimulating or depressing atmos- phere ; in oxygen or in carbon; in sulphurated or car- burated atmosphere; in hydrogen, or in mephitic exhalations of animal decay. This makes us quickly perceive the supplies needed under the various circum- stances. Nothing is of greater importance than the knoAvledge of the food, hygiene and clothing necessary under the different vicissitudes of life. The highly nitrogenous diet of the English would not do well with the mild climate of Italy, or the hot countries of India and South America. The carbonifer- ous diet of the Russians and inhabitants of Switzerland would not answer well in the United States of America. 158 PROGRESSIVE MEDICINE. I endeavour to recommend the law of Similarity in hygiene—i. e., cold water in cold countries; warm baths in Avarm countries. Cold apartments in a cold climate (60 to 65) Avould be healthier and less danger- ous than in that of 75 to 80 degrees. Generally we accept it for granted that by keeping in the Avarmth in Avinter and the cold in summer, Ave are obtaining the comforts of life, and Ave seek no further proof than that of our immediate satisfied sensations. The general disregard of the principles of the elemen- tary science, Avhich guides our physical and vital forces, and more, all our physiological organization's undoubt- edly one of the great causes of a large number of pre- mature deaths. PHYSICAL AND MENTAL LABOR. 159 CHAPTER IV. PHYSICAL AND MENTAL LABOR. Mechanical Avork is folloAved by a reneAval of forces, physical and vital. Composition and decomposition go on in a perfect reciprocal relation; the Avaste and supply must, in a normal condition, be even. The organizing process, also, must perform its vital- izing functions by assimilation, and by it nutrition becomes feasible and complete. All physicists have observed the immediate relation of mechanical force Avith physico-vital force, and that mental activity, motion and labor are indispensable to their groAvth. We find this laAv Avell illustrated in the animals and vegetables. The motion of the sap is simply physical, because it has only to supply groAvth or vegetable de- velopment. In animals Ave have more—i. e., a variety of co-ordinate forces and correlative functions con- tinuously going on for the equilibrium of the complex phenomena of organic life. Minerals possess the power of cohesion and affinity. There is an elementary force which is the basis of mine- ral formations, and its constituents are also elementary. No mineral formation could be possible Avithout elemen- tary constituents and force. We receive certain sup- plies from both, Avithout them animal life Avould be equally impossible. The velocity of light, sound and electricity is far more rapid than the current of the blood or that of ner- vous force. Electricity being produced by the process of chemi- 16jO PROGRESSIVE MEDICINE. cal and elementary decomposition, the action of attrac- tion and repulsion is the natural condition of elementary disturbance and disintegration. The oxygen runs from copper to zinc, and after the molecules of oxygen have been exhausted therefrom, they are attracted, or rather repelled, and return to Avhence they came, to receive a neAV supply of oxygen, and then are expelled by repulsion, and go back again to the negative pole. The Avind moves from a balmy air into a velocity of sixty miles an hour; it cools the earth, it forms currents Avhich are either cold or hot; giving us fair Aveather, rain or snow. It absorbs the moisture of the earth and carries Avith it either health or disease. Even the sea is excited by grand storms, and large fleets are thus carried to their destinations. All things move and live. Even the force of cohesion is a motion, produced by affinity and attraction of homo- genous bodies. Physical motion is found in this laAv— endosmosis is a process induced by affinity and capillary attraction; and exosmosis after the parts have received their nutrition. This is a general physical law. These feAv illustrations are taken in order to give more force to the argument.* Motion then is a sine qua non of existence. Electro- magnetism, positive and negative, exists in the mole- cules of the human organism. This force is static and strictly connected Avith the other forces. It is increased or diminished in accordance with the others. Motion, light, air and elementary electricity set them all in ac- tion, and devclope them to an incredible extent. In this way the current of the blood, mental vigor, physi- cal and vital forces are stimulated and reneAved. But Avhen the equilibrium of this physical combination is by some accidental reason lost, the physiological functions of the animal economy become gradually disarranged, losing the organizing force—hence inanition and decay. ' PHYSICAL AND MENTAL LABOR. 161 There is a necessary uniformity of action in these for- mative agencies, Avithout Avhich no physical laAv can be possible, and no animal organization could be attained. It is then of paramount importance that activity, me- chanical as Avell as physical, should be promoted as a great element of organization and decomposition. Action and reaction cannot Avell take place Avithout it; and assimilation, nutrition, groAvth and force, must descend step by step until the organic functions cease altogether, or in a measure, in order to supply the gene- ral economy with their support. The principles of vital force are static, as has been said, in the matter itself, and they only need a momentum in order to throAv the Avhole economy into a natural ac- tivity and develop its resources. 1.-Exercise mechanically the muscular system, and then stimulate organic activity by air, light, heat and motion. 2. Develop by proper occupation the mental faculties, and the result will be health, abundant and unceasing, and longevity. The truth that elementary forces are indispensable to the process of animal life is undeniable. Physical Avithout, vital within. The mental force is derived from the general physical phenomena, and is a correlation of all the forces. It is a third agency, higher in its source, differing from and greater than all the others. It might be said that it touches the acme of spirituality ; and its groAvth and progress are similar to the first principle, i. e. the mineral. From a mere elementary substance, from the smallest nucleus, springs this great volcanic fountain. As the highest condition of vegetable decomposition is alcohol, a spirit, a force which is capable of organiz- ing and disorganizing; so is the mind spirit-like, the ethereal substance of animal life. Let the mind remain inert and it will retrograde into 162 PROGRESSIVE MEDICINE. a state of sluggishness; just as activity Avill make it progressive and strong. In the first instance, it be- comes dwarfed and defective in every Avay. In the lat- ter case, by proper culture, it develops into beautiful harmony, and is capable of ascending to the highest pin- nacle of glory and greatness. The employment of the mind and especially the organs of sense is a physiological condition, conducive to a high- er development, and necessary to retain force and iden- tity. The first motion of a child is automatic, but from that to the first step, the development of both body and mind, is marvelous. The first condition is simply me- chanical. The first step is endoAved with the force of the Avill (mental development). And the next step is firmer and quicker and the physico-vital forces go on abreast Avith the general de- velopment of the economy. When the age of action arrives Ave must obey these laAvs in a modified and sensible Avay. From em- ployment in the open air, Ave obtain three great agencies Avhichare: oxygen, hydrogen and nitrogen; and from decomposition Ave disengage, carbonic and lactic acids, ammonia and phosphates. A simple, brisk Avalk promotes organic action, assimi- lation, and nntrition, and by means of decomposition, or- ganization goes on pari-passu. In order to demonstrate the physical conditions and agencies required in the accomplishment of a thorough physiological action, Ave have taken air, motion, light, heat, electricity, as so many factors of life giving agents and Avhen these are united Avith the proper nutrients and Avater, the elementary principles of life are complete. The gastric acid and peptones become thoroughly or- ganized, the absorbents act promptly, and the secretions of the chylopoeitic viscera continue their functions until they reach the final stage of organization by being form- PHYSICAL AND MENTAL LABOR. 163 ed into blood and tissue. LikeAvise, the secernents se- lect the caloriticients for the necessary process of heat and combustion. In conclusion, mechanical, elementary and vital forces form the great combination of physiological activity. But an opposite condition of things present to us another series of phenomena Avhich are called pathological dis- eases, being the natural result of a deviation from the physiological process already demonstrated. The terms struma, or scrofula, indicate the idea of an abnormal condition, of some kind, of the lymphatic sys- tem. This peculiar organization composes the Avhole glandular apparatus of the animal economy. All the functions of absorption and secretion are per- formed extensively by the lymphatics. The mucus follicles of the stomach and the secreting patches of Payer and Brunner's glands are all lymphatic glands Avhose functions are to assimilate and vitalize albuminoids fats, fibrin and blood. There are glands in the bronchi, in the lungs, in the mouth, and under the skin; eA^erywhere Ave find in greater or lesser degree, in number and size, a glandu- lar apparatus. This is a complex system, having the greatest influence upon nutrition and life itself. Motion increases lymphatic activity, absorption, se- cretion, and organic functions complete the physical metamorphosis. The effete materials must be eliminated by the excre- tions and remoA^ed entirely from the system in the form of carbonic acids, bile, urea, phosphates, ammonia, lactic acids, and sulphurated substances. The elements of nutrition must move on from stage to stage; from the primary to the ultimate condition of complete organiza- tion. From defective nutrition we get defective forms; and from an imperfect protein compound arises an ab- normal organization, and then a cacoplastic formation invariably takes place in some of the organs, often in- festing the Avhole economy. 164 PROGRESSIVE MEDICINE. Having ascertained that motion, or labor, is a physi- cal necessity and a paramount physiological law of organ- ization, Ave shall noAV study carefully and logically the process and results of this laAv. Statistics prove beyond doubt that those who live in the country and labor in the fields, are generally in the enjoyment of better health and constitutions than those wdio live in cities. Longevity is certainly in their fa- vor. But it must not be overlooked hoAvever that other factors are of great usefulness in the general result of the above statement, viz,—air, light, heat electricity; also simplicity of living and regularity of habits are all conducive to a healthful condition. Excitement, physi- cal and mental, late hours, excessive drinking and to- bacco, and rich food are predisposing and exciting causes to various diseases. From these sources we trace sthenic and asthenic maladies of different type and nature; complicated, or iodiopathic, as the case may be. A perverted plasma and unassimilated lymph or albu- minoids, produce lymphatic derangements; crude lymph brings about physiological and physical abnor- malities like adenitis, lymphitis, tuberculosis, etc. Phy- sical and mental inertia is an abnormal condition, hav- ing a tendency of devitalizing the forces as Avell as extraordinary great labor. All things are well that are Avisely conducted; all excesses are deleterious. 1. Every physician has met Avith cases that are not only difficult to treat, but very often embarrassing and unsuccessful; these are generally morbid mental dis- orders. The hysteria prevailing among the fashionable ladies, and the hypochondria of the idle man, are, surely, evi- dences of diseases produced by mental inertia. For these there is only one remedy, viz.: Avork or occupa- tion from morning till night. And in speaking of occu- pation in this sense, it is meant as a process of cure, a natural, logical and unfailing means ahvays to be found PHYSICAL AND MENTAL LABOR. 165 in some department and pursuit in life. The lady Avhose education and position have placed her beyond the drudgeries of mere mechanical labor, could not rea- sonably be expected to find pleasure and health in a hard manual employment. And so, vice versa, the hard Avorking Avoman could not folloAv an intellectual pursuit Avith either pleasure or success. The day is not far distant, hoAvever, Avhen mental diseases (dementia cerebralis) Avill be treated on physiological principles; Avhile the blistering and bleed- ing; the narcotics and antispasmodics, Avhich have been so freely and unadAdsedly used by the dominant school, will only be looked upon as barbarous practices and as decidedly injurious. 2. It is already thought that the laAv of similarity, in mental diseases, is par excellence the true theory of cure. This laAv of similarity is not limited to the morbid influence of medical agents, but extends to physio- logical means, or a natural mode of cure: as music, singing, reading, cheerful company; and finally, the influence of a strong healthful mind upon a Aveak dere- lict one, Avhich is an instrumentality serving for the stimulation of those elements Avhich require to be gently acted upon through a mental agency. The said two forces, one mechanical, the other psycho- logical, are indeed intended to be mutually related. "A healthy mind in a healthy body." Labor must therefore be considered under two conditions: mechan- ically as a promoter of force and health, and mentally as a developing necessity to keep a mind healthy. Any deflection from these rules is truly unphysiological and devitalizing. clinical case I. A young lady twenty-one years of age, of a lympho- phlegmatic temperament, had become taciturn, and suffered Avith general vital depression. There AArere no 166 PROGRESSIVE MEDICINE. indications of any particular physical disturbance. Her relatives Avere apprehensive as to her condition, be- lieving that she Avas on the road to physical decline. She Avas German, and had no inheritance of cachexia of any kind. She Avas suffering Avith a constant nervous cough, Avantof appetite, great prostration and insomnia. Physical Examination.—Irregular rhythmical move- ments of the heart, entirely of a nervous type. No organic disease could be detected. The lungs Avere evidently in a normal condition, both on auscultation and percussion, yet there Avas a mucus rale entirely laryngo-bronchial: She raised a Avhite, tough mucus, having no purulency Avith it. The liver Avas torpid, kidneys sensitive, and the urine of a light specific gravity and color. The triplo-phos- phates Avere not sufficiently eliminated, denoting a want of physical activity. Her physical development Avas good; her stomach and boAvels Avere disarranged, but Avith no pain or organic difficulty. She Avorked in an india-rubber factory Avhere ventilation Avas imperfect. Semiology.—The patient Avas very nervous, and suf- fered Avith the globus hystericus. She had lost her appetite and did not rest at night. She had lost some flesh and energy, and became some- what morbid, imagining all sorts of things. Her cough not only disturbed her, being nervous, but irritated the larynx, and kept up agitation of the mind. There Avas no nausea, but great depression of mind caused by a general vital debility. Pulse eighty to the minute, and quite irregular. There Avere indications of hyper- aesthesis Avith asthenia. The chylopoietic viscera did not assimilate enough food for the needed supply, in consequence of which she Avas on the threshhold of anaemia. Her voice Avas Aveak, her ideas sIoav, and she Avould cry at the slightest provocation, and loved to be alone. She had no desires or morbid appetites. PHYSICAL AND MENTAL LABOR. 167 She Avas an enigma, constantly complaining of a gen- eral lassitude, with an irritating and annoying cough. She had flushes of heat, and Avas chilly afterwards. The least thing frightened her; and she complained of short breathing and palpitation. The digestion Avas sIoav, but not abnormal in any of its functions. The biliary torpidity, Avith a partial sluggishness of organic action, Avas due to the general condition of the system. She Avas too Aveak to Avork in the debilitating atmo- sphere of the factory. Etiology.—The three great agencies—physical, vital, and mental—forming the great organic functions, Avere temporarily disordered, and thus the entire functions of organization Avere partially altered. As I have said before, I could not trace any constitu- tional defect, either inherited or acquired. The trouble, undoubtedly, Avas idiopathic, symptomatic, and Avithout any structural organic disease. She Avas not emotional—in fact, she Avas Avholly Avant- ing in this respect. Her affections Avere not at all involved by love or disappointment. There Avere no causes for ambition or aspiration; so that there Avere no traces of mental predisposition. In going further, the suggestive suspicion of an im- pure atmosphere should not be lightly considered. This, Avith other predisposing conditions—such as con- finement in close quarters", standing in one position, hot rooms in Avinter Avith an artificial moisture (steam), and, again, irregular meals and insufficient rest, turned the organic functions from their normality. These are the only causes Avhich Ave can account as the true factors of the loss of physico-vital equilibrium. In analyzing this short etiological revieAV, Ave soon perceive that a depressing hot atmosphere, gases of sulphurated hydrogen, and mercurial preparations, Avhich are connected Avith rubber making, croAvded rooms and constant moisture, Avere quite sufficient 168 PROGRESSIVE MEDICINE. cause to produce a physico-vital change, by sloAvly poi- soning the very foundation of life. The extraordinary surroundings Avith Avhich this girl Avas obliged to live Avere such, that disorganization would have taken place sooner or later in some form. And Ave knoAv by experience how many structural diseases these poor factory people are subjected to in all departments, and even under the best sanitary regu- lations. She had a good home and country air, two elements of protection. Medical Treatment.—In this case wTant of mechanical activity Avas not the cause, but rather a poisonous at- mosphere Avhich pervaded her Avhole economy. And this Avill prove that diseases may be very similar, while proceeding from a different origin. R\ Belladonna, 3-dec. gutt. xii. Aqua distill., f ii., and fy. Aloes 3-dec. 3 i. M. chart, xx. Dose—One teaspoonful eA-ery tAvo hours alternately; beef tea and milk, with brandy, as nutrients and easy of digestion. I called on the fourth day, and although she Avas someAvhat better, the trouble Avas still there. I prescribed li. Pulsatilla, 3-dec. gutt. xii. Aqua font, f iii. IjL Bryonia alb. 3-dec. gutt. xii. Aqua distill., f ii. Dose—One teaspoonful every hour alternately; and ordered rare beef, mutton, clams, cocoa, and eggs. On the eighth day I returned and found her about the same. I ordered the folloAving: ffc. Potass. Bromidi, 1-dec. 3 i. M. chart, xx. p. Ferrum phosph. 3-dec. 3 i. M. chart, xx. Dose—One poAvder every tAvo hours alternately, Avith PHYSICAL AND MENTAL LABOR. 169 bathing in salt and Avater; sherry Avine after eating. I continued this treatment for a Aveek, at the end of Avhich the cough had ceased and the secretions become natural. Her sleep returned, and she Avas thus restored to health. clinical case II. A married lady of thirty-five years of age sent for me in haste desiring my advice professionally. She Avas out of health and did not knoAv Avhat Avas the cause. She Avas intelligent, had all the comforts she Avished for, and yet her health Avas failing. Physical Examination.—Her general appearance Avas good; both lungs and heart Avere sound. The digestion Avas imperfect: the secretions Avere acidulous. She had leucorrhea. Kidneys Avere acting normally and the liver Avas organically sound, but functionally disturbed, and its secretions abnormal. Physically she Avas deli- cate and lightly built. Semiology.—She Avas pale, movements Avere feeble and pulse sIoav, irritable and asthenic; she slept badly, having horrible dreams. She had lost all her former interest in domestic duties. She had apparently lost flesh; her strength Avas fail- ing her; noise, or even talking Avould annoy her. She suffered Avith eructations and looseness of the boAvels. Chylification Avas imperfect, and the intestinal digestion gave her a good deal of uneasiness. Chilliness and trembling,|and coated tongue Avith Avhite fur. She Avas distressed more mentally than physically. She relinquished all social pleasures and considered herself an incurable iiiA-alid. And yet all the organs Avere structurally sound, Avith, of course, a degree of ab- normality in their functions alone. There Avas an asthe- nic condition of the brain threatening dementia, hallu- cinations or delusions, Avith great prostration. These were symptoms of a serious character. 170 PROGRESSIVE MEDICINE In examining the case Ave find the secretions to be changed, and hence tissue changes must folloAV. Phy- sical or rather physiological change, brought about con- ditions of vital disorder which reflected an influence upon the brain. The physical debility from chylopoietic disturbance had brought on a mental irritability and debility through Avant of nutrition. There is a great necessity of making a correct differential diagnosis in these complicated cases, because that determines the whole treatment. The great variety of mental disturb- ances and their similarity render diagnoses difficult and complex. There are simple irritabilities from nervous excite- ment, with perfect nutrition ; and there are irritabilities and debilities, produced by a plethoric condition and others by anaemia and asthenia. In these cases the most skillful physician may err in judgment. Etiology.—We have to consider: 1. inheritance; 2. education and acquired habits; 3. constitution; 4. mental and emotional disposition; 5. social manner of living; 6. organic torpidity. There Avas no taint of inherited mental disease. The second point had something to do Avith her physical Avant of development, because of indulgence in so-called comforts; and this includes the third point, Adz., the constitution. The fourth point is a matter of consider- ation, as there Avas a predisposition to mental excite- ment and emotional paroxysms. The fifth Avas an exciting cause, and the digestive disarrangement Avas the physiological and primary cause. These agencies diminished the general tone of her system, and Avere eminently devitalizing. The education and habits are cither conducive to health or disease, and those indulged in by her Avhen a child fostered a physical debility, Avhich Avas folloAved by enfeebled functions of organization. This gives us, PHYSICAL AND MENTAT LABOR. 171 also, the true microscopic light of the causes of mental and emotional symptoms. These two cases are at variance as to the origin of the illness, but the symptoms and general effects are very similar ; only the former Avas more subject to treatment than the latter; and it is Avell to notice that diseases proceeding from indulgence in vice are less amenable to medical influences, and are often entirely beyond the scope of therapeutics. Here there are the antipodes. The first case a poor working girl, whoso lot had compelled her to work, knoAving no rest and no comforts. The other, a lady of leisure, and surrounded by luxuries, indulging herself in fancies, emotions, and dreams, until her system be- came morbidly affected; and, strange to say, the same results, viz., mal-assimilation, irritability, inanition, and hvperaesthesis, were in both cases strongly marked. And although the symptoms Avere alike, the fountain whence they came being different, the treatment—not only therapeutical, but also hygienic and dietetic- must be different. The two cases came, as we have seen, from a dissimilar source; consequently, the treat- ment must be essentially opposite. In the first instance the patient required merely physical rest, nutritious food, wines, amusements, cheer- ful company, activity of the mind, etc., with invigorat- ing agents and soothing medicines, to re-habilitate the system to regain its physical equilibrium. " In the second case Ave must look more at physical and elementary aid than either hygienic or therapeu- tical. Physical motion and mental rest. Exposure to all weather, if avcII protected from taking cold. Simple, nourishing diet, but no stimulants. No amusements appealing to the senses; no social excitement; air, light, work, heat, and mental quietude. This can only be secured in the country, and a permanent cure obtained by a long residence and physical employment there. 172 PROGRESSIVE MEDICINE. Forbade her all stimulants and all emotions. The first patient, on the contrary, required stimulants, rich diet, and mental activity. In the former instance the disturbance Avas mephitic, over-action, and poor diet; in the latter, Avant of phys- ical action, mental hallucination, morbid desires, and dietetic indulgence. In the first the physical force Avas OArerAvorked and the A'ital poisoned; in the second the mental and emotional forces Avere intensified to the highest degree at the expense of the physical. Hygiene and Dietetics.—In this latter case there Avas little to suggest as to hygiene, for she bathed frequently and used precautions Avhich Avere Avell knoAArn to her. Yet there Avere some things that she neglected, e. g. early hours and exercise, Avhich Avere at once recom- mended. Her diet Avas changed for a simple beef-soup strained and roast beef or mutton. Eggs, bread, cocoa, fish, cream, lentils, peas, tomatoes, etc. Potatoes and rich pastry, or hot bread and cakes Avere forbidden. She Avas ordered early hours and exercise. She Avas sent into the country and reported every Aveek. Medical Treatment.—The difference betAveen these tAvo cases Avas this: one had exhausted vitality, and physical debility Avas brought about by those unavoid- able circumstances folloAving poverty, hard labor and insufficiency of repair; the other Avas exhaustion by those agencies Avhich produce disorganization of the phenomena of life and of those physiological metamor- phoses that are indispensable to the process of vis vita3 and the pabulum vita\ Therefore in the second instance the folloAAring thera- peutical treatment Avas considered necessary: P Pepsine 3 i. Acid Hydroch: gutt. xx. Aqua bulient z iv. # Lactucaria 3-dec. gutt. xxx. Aqua distill., f ii. PHYSICAL AND MENTAL LABOR. 173 Dose.—One tea-spoon of lactucaria every hour during the day; and the digestive remed}*—one tea-spoonful before meals so as to aid the chyme in organizing. I saAv the patient four days after and I Avas pleased to find an improvement. I continued by giving her R. Pulsatilla 3-dec, gutt. xxx. Aqua distill., f iii. And pepsine the same. On the tenth day I found that she Avas doing Avell but that insomnia and irritability existed in the brain. I prescribed: R. Phosph., 6-dec, gutt. xx. Aqua distill., ? ii. And R. Ferrum phosph., 3-dec, 3 i. M. chart, xii. Dose.—Qne tea-spoonful of the liquid alternately Avith the poAvders. I continued this treatment for ten days longer mak- in0* tAventy days of medical treatment: sac Avas so much restored that I considered that exercise, open air, and complete mental rest Avould accomplish the remainder. Supposing I had treated this case with cathartics and opium, or Avith antispasmodics and stimulants? Could those remedies supply an exhausted constitution? Had I treated her symptomologically alone, Avithout the proper knoAvledge of the pathognomonic symptoms of her dis- ease I should have treated headaches, leucorrhoea, chil- liness, constipation, trembling, insomnia, ill-humor, weep- ing, and a myriad of secondary symptoms, omitting alto- gether the primary causes. I considered it logic to supply those elementary prin- ciples of physical force Avhich she so much needed. I also considered it right and proper to supply an ingredient that Avould help the process of chymification, thus rendering digestion easy and perfecting assimilation. It Avas also necessary to take into due consideration the 174 PROGRESSIVE MEDICINE. asthenic and anaemic condition of the patient as being the result of this general disarrangement, and supplying phosphorus and iron to the devitalized corpuscles of the blood. And had she continued under my treatment, I should have given her magnesia, phosph., natrum phosph. and kali chloridi in order to supply alkalinity to the plastic force. CLINICAL CASE III. I desire to shoAv clinically, that Ave are all predisposed to diseases peculiar to climate, seasons, food, mode of liATing, occupation, correspondingly Avith diathesis and ^ idiosyncrasis. Physical Examination.—A young Avoman tAventy-eight years of age, of a bilious lymphatic temperament and subject to pituitous secretions, Avhich denoted a consti- tutional Aveakness. Her physical development Avas good, her lungs Avere sound, heart regular but feeble, radial pulse, Aveak and small in \rolume. She presented an anaemic condition. Uterus tender on pressure, menses scanty and colorless, liATer tender and enlarged, stomach painful, boAvels tym- panitic and kidneys irritable. Asthenia Avas apparent Avith apepsia and insomnia. Great mental depression; and the pallor of her face denoted a peculiar Avant of vitality and plastic force (Adynaemia). Semiology.—This woman Avas a seAving mistress and employed her machine constantly. She Avas confined in small quarters, and in the Avinter, in hot rooms. Her business required her to go out frequently to seAV for families; and she naturally found a great variety of cooking and food; this predisposed her to dyspeptic or rather digestive troubles. She Avas fond of coffee and tea Avhich no doubt she drank to excess. Her complexion had changed from a bright rosy color to a greenish yelloAv. She became easily exhausted. Her stomach felt uncomfortable and PHYSICAL AND MENTAL LABOR. 175 sensitive. She had intestinal borborysms Avith constipa- tion. Gaseous eructations, sometimes acidulated, some- times bitterish, of a sulphurated nature or (nitrogenous) The papillae of her tongue Ave re prominent and aptheous patches Avere seen here and there. She suf- fered Avith head-aches and pain in the back; Avith nausea and general malaise. Her physician (a rational of the old school) employed evacuants or cathartic doses of drugs in order to remove the crudities in the intestinal canal or irritating materie-morbi, Avhich treatment Avas not curative, but, on the contrary, un- scientific and empirical, producing a physical debility of the enteric organs. He succeeded admirably in pro- ducing constipation and irritability of mucous mem- branes, and exhaustion of the splanchic nerves, and thus she was constantly prone to relapses and repetitions of the troubles. Her mental condition Avas no better than the physical. She had fears and delusions of the most ridiculous kind. She had nervous prostration in the morning. She had no appetite or desire for any kind of food. Urine Avas scanty (specific gravity 1030) and had an ammoniated sAveetish odor, Avith foam (ferment- ing), and a Avhite crystalized sediment stuck to the A'essel, Avhich proAred to be urate of ammonia. She Avas often dejected and Avept Avithout much cause. Her nervous system gave evidences of great Avant of nutrition and hence force; she had lost control of her- self; her emotional senses ran aAvay, as it Avere, like a Avatch Avithout the balance Avheel. The physician in attendance, a true allopath, told her she had a uterine disease, Avhich umvise prognostication frightened the patient into an hysterical condition. It is true that there Avas an hyperaemic condition of the uterus and ovaries, as there Avas an irritability of the absorbents and acidulated secretions; but certainly there must be a Avide difference, I ATenture to say, be- 176 PROGRESSIVE MEDICINE. tween hyperaemia and phlogosis, as betAveen irritability and structural diseases of the organs. The exaggeration of the disease and the unguarded diagnosis given, Avithout the least pathognomonic lesion to bear out the Doctor's diagnosis, produced unnecessary alarm, and misguided treatment. The exciting cause, I must acknoAAdedge, AAras strongly in favor of a uterine trouble, but it Avas surely a simple case of irritability caused by.constant treading upon the seAving machine, and this irritability, (from motion,) caused a hyperesthesia and hyperaemia of the uterus and ovaries. These Ave re the predisposing causes: Confinement, Avant of air, and stimulating, indigestible diet. The treading on the machine, Avas the exciting and most direct cause. There Avere no physical remote causes of inheritance. The etiology of the case Avas sufficient to sIioav no organic lesion. There Avas no pain indicating an inflammatory con- dition of either the uterus or ovaries; there Avas no fever; none of the pathognomonic signs of uterine perimetritis. In its place I found asthenia, a running down of the physico-vital forces, anaemia and inanition bordering on typhoid fever. She Avas cold and anaemic, with irritability of the kidneys, as Avell as the uterus; she could not stand on her feet Avithout feeling a drag- ging doAvn sensation of the ligaments of the uterus. Her food disagreed Avith her, having evidently an en- feebled gastric j'uice and peptones, hence a Avant of proper chymification. Her head-aches, hepatic engorge- ment and gastro-enteric disorder, Avere all consonant Avith the abnormal functions of digestion. The lympho-phlegmatic temperament Avas a physical fault, Avhich predisposed her to catarrhal diseases,pelvis cellulitis, follicular leucorrhea, lienteria, follicular dyspep- sia ; glandular diseases, tumors, polypus, ulcerations, etc. and tc aH forms of asthenic diseases. And from what has been said, we can, surely, de- PHYSICAL AND MENIAL LABOR. 177 tect Avith sufficient accuracy these functional, organic and general disorders. I failed to appreciate the diagnosis of my learned con- frere as all the physical and vital signs of this case Avere those of debility, apepsia and anaemia. Etiology.—Summing up our case's generalities, it is, I would venture to say, one of common occurrence anions: the poor seAving Avomen of all countries. It is one of those Avell authenticated abnormalities of the digestive organs. In conclusion, the symptoms Avere pathognomonically those of progressive asthenia, involving all the functions of organic life—the blood, the correlation of forces, and the organic structure and functions. 1. Irregularities in the hours of eating and rest. 2. A great variety of food. 3. Sedentary occupation depriving her of physical exercise, air, light, and hence physiological metamorphosis; the organs and their functions remain- ing in a semi-state of inertia. 4. Posture by bending the body over the stomach and uterus. 5. Strong coffee, tea and spices. 6. Constant Avorry and disappoint- ment. The pathological conditions therefore Avere gen- eral or systematic, functionally organic (not structural) and a physical predisposition to morbid groAvths and pituitous secretions Avith hyperlymphoma, and l}'m- phatic diseases general^. Hygiene and Dietetics.—Doctor Chambers' treatment by tonics and alternatives Avould haAre sadly failed alone. Similia also Avould have been of little or only temporary help Avithout the adjuvants of the laAv of hygiene and nutrition. The system was to be re-invigorated so that the recuperative power of nature could be re-established on the proper principle of organic force. Organization cannot be re-established by medicines alone. It is Avell demonstrated that dynamical forces depend upon a unity of agencies in order to form organic life. I ordered Avarm salt Avater baths every other night. 178 . PROGRESSIVE MEDICINE. Perfect rest in a recumbent position and quiet in the room, except the cheerfulness necessary in every sick chamber. Diet: beef-tea, oysters, clam soup, Avine soup, brandy Avith her food, eggs, game, etc.; all nitrogenous food. And as soon as she Avas able I sent her in the country for fresh air, exercise and simple food. Coffee and tea Avere forbidden. Medical Treatment.—I consider belladonna as a great vital invigorator, stimulating glandular functions and organic action. I therefore prescribed R. Belladonna, 3-dec. gutt. xl. Aqua distill., f iv. R. Podophyl., 3-dec. 3 i. M. chart., xxx. Dose—one teaspoonful of the Belladonna and one powder every hour alternately. I called on the third day and found her urine clearer complexion better, pulse fuller, and less tenderness in the stomach, boAvels and uterus. I continued the treat- ment. On the sixth day she Avas decidedly better. I could see the influence of the proper dietetics upon the blood, yet her appetite and boAvels Avere not sufficiently improv- ing so as to keep on Avith the treatment. Changed for R. Quinia sulphas, 3-dec. 3 sj. M. chart., xxx. R. Aloes, 3-dec 3 i. M. chart., xxx. Dose—one poAvder ever two hours alternately. And noAV to justify this prescription, I Avould refer to the pathogenesis of quinia upon the liver and spleen, and upon the caeliac plexus of nerves and hence portal cir- culation. The second, or aloes, hardly needs any patho- genetic explanation, for every homoeopathic phvsician understands the relation of the pathogenesis of this drug to hepatic torpidity and uterus. The patient improved. The liver acted under the effect / PHYSICAL AND MENTAL LABOR. 179 of the above agents, and the boAvels and stomach became invigorated by the dynamic force imparted by the quinia. I consider this drug well chosen for all diseases of the chylopoeitic viscera, bilious and splenic troubles, and that it is only through the laAV of similarity that this great object is obtained. I finished the treatment Avith phosphorus and ferrum oxydum, the third trituration. I used, also, secalae corn, and actea racemosa, Avith hot applications to the uterus. R. Secalae corn., 3-dec. gutt. lx. Aqua distill., f ii. R. Phosph., 6-dec gutt. lx. Aqua distill., f ii. R. Ferrum peroxid., 3-dec. grs. lx. Dose—one poAvder eATery tAvo hours alternately Avith the secalae. R. Actea Racem., 1-dec gutt. lx. Aqua distill., f ii. Dose—one teaspoonful every tAvo hours alternately. CLINICAL CASE IV. Mrs. B., age forty-five years, of a nervo-bilious temper- ament. She AVas married tAvice, and her second husband Avas uncongenial to her in many things. She Avas very sensitive, Avith refined manners and tastes, A'ery impul- sive and had many Avishes and illusions ungratified. She had no children. Physically she Avas lightly formed —black hair, dark complexion, and of a strong Avilful temperament. She complained of having suffered for years Avith a bilious dyspepsia, complicated Avith renal and cardiac troubles; she complained also of pain in her back, nausea, and Avas frequently nervous, despond- ing and fretful, Avith paroxysms of hysteria. She Avas Arery active, and imprudent in diet—drank ale, Avhich ahvays disagreed Avith her. She had periodical head- 180 PROGRESSIVE MEDICINE. aches, and eructations of a sour, bitter taste. She led a sedentary life, had nothing to do, and consequently Avas ahvays dissatisfied. She Avas suspicious and imag- inative, very economical, and at times irritable and weak. She considered herself an invalid and a victim of bad fortune. Physical Examination.—Lungs perfectly sound. The heart Avas quick in action and small in volume. The rhythmical sounds of the heart Avere irregular. She suffered from dyspnoeas and cardiac agitation. The stomach and liver Avere tender on touch; the liver Avas also organically enlarged, and hard, and gaATe indica- tions of partial suppression of the biliary secretions, and therefore left an impure, venous blood to circulate through the economy. The kidneys Avere suffering from the general condition of things and had been secreting oxalic acid crystals. The urine Avas dark, heavy, unhealthy, and strongly ammoniacal. Skin of a pale yelloAvish hue; eyes dull arid Avanting in lustre; boAvels constipated. The nerA-ous system was irritable, Aveak and lacking both physical and vital force. Nutrition Avas evidently imperfectly carried on, and the great centre gave signs of mental debility and insomnia. She had horrible fits of temper, despondency, inability to form ideas, or put them together, giving rise to the most ridiculous notions, as to all sorts of domestic comforts and discomforts, Avhich she succeeded perfectly in doing. Loss of appetite, great prostration, nausea Avith eructations of a sour, bitter taste. Weep- ing and scolding alternately. This examination was made on my second visit. Semiology .—It was some five years ago that I was called to see this lady who Avas thought to be cither dying or insane. Upon entering the room I saw at a glance that things Avere in a condition of disorder, although quietness ex- isted at the time. PHYSICAL AND MENTAL LABOR A 181 The patient Avas apparently asleep and I stopped to get some preliminary information from the attendants. It Avas but a moment, Avhen I heard her moaning and moving. In approaching her, I Avas faced by two eyes, not the pleasantest to behold. They Avere Avild, angry and Avicked. I took her Avrist and asked how she Avas. The answer Avas, " None of your business," and this Avas soon folloAved by a jump and an attempted grasp at my throat accompanied by an oath. I disengaged myself quickly from the aAvkAvard position in Avhich I so unex- pectedly found myself, and, after receiving several kicks and blows, I retired Avith the full conviction that she Avas not to be trifled Avith. Her husband laughed at my discomfiture, but the affair soon became too serious even for fun. It took two strong men to prevent her from doing much mischief to herself but, I believe, more to us; hoAv- ever, she made things lively for a time,and it Avas Avon- derful, Avhere that little lady found so much strength ! During this paroxysm I could only give her something in order to stop her antics and prescribed R. Chloralum hydratis, 3 i. Aqua distill., f i. Dose—one teaspoonful every half hour till better, then every hour, prolonging the interval. I found that smaller doses than those of the dominant school Avere better fitted for an irritable brain. The danger of chloralum is in its uncertain action upon the economy, and particularly upon the brain and the blood, having the tendency to disintegrate its corpuscles. It has been ascertained that it not only keeps the blood from coagulation, like ammonia, but Avould soon liquify it, destroying its fibrinous elements. The collapse produced by chloralum is due to a sud- den action of the agent upon the dynamical forces of the cerebrum, causing dyspnoea, and cardiac paralysis with a fall of temperature, which is a pernicious efi'ect 182 PROGRESSIVE MEDICINE. in the extreme to the animal economy. It is, par ex- cellence, an adynamical agent, and therefore to be used Avith care. Its action upon the nervous system is primarily on the S3"mpathetic ganglia, and afterwards it acts upon the cerebrum and heart. On the second visit, I made my physical examination already given; then she had returned to her normal condition of mind: the medicine was well indicated and diminished the cere- bral hyperaesthesia and the storm Avas over. Nature resumed its calmness and sleep Avas sloAvly and com- fortably obtained. She had a small pulse, yelloAv coated tongue, pain oxer the stomach and liver, both organs being irritable. She had no appetite, Avas very nervous, had irritation of the vocal cords with aphonia, great prostration and mental exhaustion. Her head Avas light and painful. Etiology.—She had gastro-hepatic trouble caused by drinking beer and from Avhich effect the chylopoeitic viscera became torpid and inactive. She suffered Avith renal irritability caused by the same beverage and, I may safely add, liquor. Truly, her physical organization predisposed her to nervous troubles, besides being excited by stimulants. Nothing could be expected from such habits but mal- assimilation and mal-nutrition. Her Avhole organization Avas disturbed, and the process of organic function Avas partially suspended. The splanchnic and ganglionic systems of nerves Avere very sensitive and very much irritated. There Avas a general irritability of the Avhole nervous system as a secondary result of overstimulation. Other predisposing causes Avere. 1. Great indulgence and indolence Avhen a young girl; she Avas capricious and AAdiimsical. 2. Indigestible food, like pastry, cakes, and candies Avere used Avithout the least prudence. 3. Sedentary life and novel reading. 4. The inactivity of the mind led her to all sorts of morbid desires and fancies, producing depression of mind and discontentment. PHYSICAL AND MENTAL LABOR. 183 4. Indulgence in strong coffee and tea, and highly sea- soned food. These Avere sufficient causes to enfeeble the best of constitutions, and change the nutritive process into an abnormal condition. Had this lady been born a poor country girl, obliged to AAork in the fields for her daily bread, her delicate constitution Avould have been stronger and a better organization Avould have been the result. This case shows the evidence of mal-assimilation and inanition as the result of a delicate constitution, abused by indulgence and vice. When the great co-ordination of forces has been disarranged, no Avonder that the physical economy loses that beautiful harmony of action, Avithout Avhich there can be neither health nor lomr existence. It is obvious that our first step is to re-establish the physical equilibrium in a rational manner. Hygiene and, Dietetics—1. It Avas necessary to remove the proximate causes either predisposing or exciting. 2. Tranquilize irritability and excitement, thus return the economy into a normal uniformity of action. The former causes could only be overcome by folloAving a hcav course of life : e. g. Employment of body and mind; ex- ercise in the open air; proper light and nourishing diet; and above all, total abstinence from stimulants. This mode of procedure Avould,in time, bring back phy- sical vigor and physiological metamorphosis. It Avould also increase dynamical forces by elementary agencies acting specifically upon the nutritive functions. The return to a normal condition of the impaired or- ganic functions, can only be hoped for in the proper conception of Avhat elements are needed, and Iioav to employ an equivalent of homogeneous agents to bring this desirable idea into a practical form. I therefore ordered leguminous and nitrogenous diet, e. g., beef-tea, cream, chicken, light broth, oysters, 184 PROGRESSIVE MEDICINE. clams, fish, eggs, vegetables, peas, beans, lettuce, toma- toes ; a Avoiding the starchy materials. Bathing in salt and tepid Avater every day. Mental rest, cheerful company, good books to read, etc Medical Treatment.—In connection Avith the hygiene and diet, medical agents Avere chosen according to their therapeutical and specific action upon this morbid phe- nomena. I ordered a sinapis cataplasm to be applied upon the back and front of the liver, because that organ Avas in such a state of torpidity that I thought it physiolo- gically right to excite a physico-vital reaction. To this I added simply fomentation of hot hops steeped in vinegar and Avater. This topical indication Avill be easily understood, Avhen Ave take in consideration the physical influence of heat and moisture upon the hepatic regions. I cannot recommend too strongly heat upon the liArer and all glandular structures. The remedies giA'en Avere as folloAvs: R. Podophyl., pelt. 3-dec. 3 i. M. chart., xxx. R. Capsicum, 5-dec gutt. xxiv. Cinchona, 3-dec Aqua distill., f ii. Dose—one powder every hour alternately with one teaspoonful of the liquid. The pathogeny of capsicum is Avell knoAAm to the profession, and it hardly requires any revieAv. It is Avell knoAvn to produce spasmodic cough, irritation of the throat and tonsils, burning at the stomach and stimu- lates the genito-urinary organs. It has a strong influence upon the vagi and pneumogastric nerves, and so also upon the cerebro-spinal centres. Its extraordinary poAver to control capillary circulation, also brings excess of blood to any given point, or Arice-versa, it scatters any sanguine tumefaction, congestion and stasis. It enables the vis medicatrice naturae to remove con°;ela- PHYSICAL AND MENTAL LABOR. 185 tions or congestions, reducing SAvellings as promptly and as effectually as belladonna. Its influence upon the nervous system in all the derangements of the sympa- thetic and vasa-motor systems and upon the ganglia of the .lymphatics, is important and decidedly therapeu- tical. The cinchona adds to it those properties which it requires as an invigorator, i. e. blending the tannic acid and thus strengthening capillary contraction and cellular force. Those tAvo ingredients I consider homogeneous and correlated in action. Of podophylum, I need not assume any neAV discovery in regard to its action, as it is Avell knoAvn by both schools. She improved Avonderfully under the treatment and in a feAv days had almost regained her health. But I thought that an exhausted nervous sysiem and mental force Ave re conducive to organic hyperaemia and lymphatic complications. I therefore continued R. Nux vom., 3-dec. 3 i. M. chart., xxx. R. Natrum phosph., 6-dec 3 i. M. chart., xxx. These agents had certainly specific action upon the nervous system both sensory and motor)7; be- sides the natrum has a most useful effect upon the cliemico-physiological elements of the gastro-enteric juices. In folloAving this principle I succeeded in elimin- ating much that Avas effete matter, and aided the vis- medicatrice of nature in all its intents and purposes. She Avas also ordered A'ichy Avater—one tumbler morn- ing and night, in order to act gently but surely upon the elementary alkalinities of the juices and blood. CLINICAL CASE V. Mrs. P., a married lady, fifty years old, of a bilio- lymphatic temperament, predisposed to attacks of phlegmasiae. 186 PROGRESSIVE MEDICINE. Had dark hair, fair skin and large blue eyes, and although her general appearance Avas that of a strong person, yet she had delicate fibres, very impressionable, but of a good frame. She had had eleven children and her numerous conceptions had left a diminished physi- cal and vital force. Her predominating idiosyncrasis Avas decidedly phlegmatic and prone to lymphatic dis- orders. Taking in consideration the rearing of such a large family she shoAved considerable strength and Avas active, fora person of her age and temperament. Her nervous excitability Avas derived from debility and exhaustion of the general economy. Her domestic duties confined her too much to the house and she Avas subject to all the annoyances of housekeeping, etc ; otherAvise she Avould be placid, though her stamina lacked fibrinous force. When I saAv her she Avas suffering with great pain in the stomach and boAvels. She had been an invalid for tAvo years and had had the advice of several allopathic physicians, among the number Doctor Saver of NeAV York. I found her paroxysms quite serious, and threat- ening some sort of metastasis elseAvhere. She Avas at times in a state of collapse, and Avas very anaemic and emaciated—her general appearance indicated great physical disturbance. She Avas often in agony. The antispasmodics and hypnotics had been used by the Allopaths ad nauseam, and Avere found to be rather hurtful. She tried the cathartic treatment with no bet- ter effect. She had had all sorts of cataplasma and tonics with the same result. The disease was neA-er reached because never understood. Semiology.—She suffered great pain, spasmodic at times, but ahvays continuous from the epigastrium doAvn to hepatic and enteric regions, and in turn, up to the heart. She had emesis of a mucous stringy slimv acid fluid denoting mucous and follicular trouble of the stomach ■ PHYSICAL AND MENTAL LABOR. 187 the gastric juice became intensely acrid and increased in quantity, and at the same time diminished the annual- izing principles (or peptones). There Avas constipation, due to suppression of biliary secretions; great eructa- tion and flatulency. She could not digest the smallest quantity of food, and Avhen taken she suffered intensely. But even Avhen fasting she suffered Avith eructations and borborygmus, shoAving that a gas Avas forming in the intestinal canal deA'oid of alimentary material; this Avas an unmistakable sign of the self-production of car- bonated hydrogen gas, resulting from a Ioav and ferment- ing condition of a mucous accumulation in the intestines. This inflation and muscular irritation produced contrac- tions and spasms. It is a pathological condition, that absence of bile in the intestines alloAvs the faeces to degenerate into fer- menting matter; as the bile is not only a physiological condition for the peristaltic movement, but also a sub- stance Avhich prevents animal decomposition. I found the urine dark, offensive and of an ammoniated char- acter; its specific gravity being 1030. Pulse small; heart's action regular, but feeble; cold hands and feet; circulation deficient and decarbonization imperfect, hence defibrinated blood; serum and Avhite corpuscles abounding. At times she Avould be apparently better, only to have a return of those dreaded paroxysms. The seasons of spring and fall predisposed her to these attacks. Her habitation Avas not desirable being near a pond Avhich Avas supplied by spring Avater from many sources in the neighborhood. The vegetation Avas luxuriant and rank, shoAving moisture, Avhich constant supply Avas a source of poison. It Avas a question Avhether her trouble originated from ma- lirious effluvia, caused by vegetable decay and stag- nant water. She suffered with pyrosis and general exhaustion. Mal-assimilation and inanition Avere undermining the 188 PROGRESSIVE MEDICINE. physical force to a fearful degree. It Avas, therefore, of the utmost importance to re-establish a certain amount of nutrition, for life Avas rapidly losing its recuperative poAver. This good lady had had her share of troubles and anxieties. Her ambition and pride had succumbed often to unavoidable mortifications Avhich rendered her miserable, and produced mental irritability. Her will overtasked the nervous system and reflected its influ- ence upon the ganglionic system, and agitation and irri- tations Avere the consequences. She had experienced the ups and doAvns of an eventful life, and such people are often invalids in their old age and suffer from ener- vation and inanition. Her menstrual change had not been Avell directed, and it took place under many difficulties, and conse- quently left her Aveak and unable to keep herself in a normal condition; phlogosis of different types attacked at times one organ, and at other times produced a com- bination of symptoms, almost indescribable; the head, heart, kidneys, and sympathetic system Avere often dis- ordered ; and the mind and disposition Avere becoming depressed and irritable. The organic functions, and hence vitalizing forces, Avere deficient and unable to perform their necessary work in the accomplishment of the various physiolo- gical metamorphoses for the sustenance of the animal economy; in another Avord, Avaste Avas greater than the supply. Several factors indispensable to life were dis- regarded, not only by the patient, but by the physicians, i. e., oxidation, motion, air and light; therefore, the re- sult Avas an unavoidable chemico-physiological derange- ment of digestion and assimilation. The sympathetic svstem Avas superlatively involved almost to a hysterical degree. Her mental functions Avere impaired, and she imagined all sorts of evils. Here, I am sure, Ave had suppressed biliary difficulties from Avant of organic ac- PHYSICAL AND MENTAL LABOR. 189 tion, and blood, Avhich Avas Avatery, and Avhich had be- come impure, and through its medium sent poison to the nearest eliminating organ, the kidneys. Etiology.—Remote causes: A large number of concep- tions, mental anxiety and hard Avork. Proximate causes: these Avere links folloAving the pre- existing conditions and aided by change of life, exhaust- ed vitality and ganglionic irritability. Hyperaesthesia and disorder of the chylo-poietic viscera interfering Avith the process of histogenesis. The dynamic func- tions Avere all disarranged and enfeebled. The gastro- hepatic disorder, caused a mal-assimilated chyme Avhich being throAvn in the intestinal organs, overcharged them with materials of a crude nature. 3Iedical Treatment.—There was a great complication of symptoms, pathological, sympathetic and reflex, thus rendering the case most difficult to manage. There is great difficulty in finding a medical agent that Avould cor- respond Avith all the objectiA-e and subjective symptoms, and so Ave must use those that are analogous to the gene- ral symptoms, and specific with the pathological ones, or with those derived directly from the lesion. The danger of prescribing symptomatically in a gen- eric sense, is that Avhile Ave are treating mere effects, Ave are apt to neglect the salient points pathognomonic of the disease. An Allopath Avould prescribe a concoc- tion irrelevant and illogical, of many drugs in a pint of water, shake them up Avell, and each agent must do or should do, just as the classification of his materia medi- ca says ; a most illusory, A-ague, and dangerous practice. But on the other hand, I believe that a mere Baby- lonian Symptomologist Avould do no better than his con- frere, the Allopath. This mode of treatment is surely not rational medicine. It appears to me that something more tangible and more trustworthy should be the great aim of all true physicians, than simply speculations, de- ductions, and illusions. Let us base therefore our 190 PROGRESSIVE MEDICINE. symptomology on pathology, true and real, and from that, extend it outwards to lighter symptoms and cor- ralated uniformity of action. Does this or that remedy correspond in greater or lesser degree Avith the patho- logical lesion and symptoms of the disease? Does it correspond Avith the peripheral and sympathetic signs and organs? Does it cover the pathognomonic indica- tions first, Avith the collateral complications also? FeAv indeed are the remedies that are thus knoAvn. Some cover objective symptoms, but not the subjective and organic ; and some are specifically pathogenetic, caus- ing like morbid effects upon some organs or forces, and others have no morbid relation to any special organic disease, but have caused, perhaps, some general dis- turbance. The specificity of drug action is all important to the disease and the physician. " The greater the similarity," says Hahnemann, " the greater the homoeopathicitv of the remedy,"—but yet, Ave should never forget the path- ological or morbid relation necessary between drugs and diseases. I cannot agree Avith Dr. W. Sharp's Organ- opathy, for there are many organs that are only sympa- thetically affected, the remote cause of Avhich is physico- vital, or which is from the general systems, or from the great centre of nerves, or the spine, or the lesser or greater circulation and A'ice versa. The organs' reflex action upon the great centres is Avell knoAvn. We may have an hepatic trouble from malaria, food, nervous in- fluences, and habits; could Ave cure that liver Avithout removing the causes? and yet there might not be any signs but those of the liver. We may have palpitation of the heart from either smoking, or drinking coffee, or mental excitement; Avould the heart get Avell Avithout removing the cause? and yet the heart is the organ that gives us the alarming symptoms. Organopathy as a system of medicine is a chimera. We must therefore prescribe specifically and generally, PHYSICAL AND MENTAL LABOR 191 only, Ave must select the drug that has, besides general symptom, the characteristic morbific feature similar to the disease, in preference to unmeaning generalities. This poor lady had a mania for an indiscriminate use of Avater; irrespective of age, temperament or disease; and at the very first glance, any medical eye could have seen the fallacy of her theory in her OAvn case; for, if Avater had had the charms of cure-all, she certainly Avas a living rebuke to that statement. Water cure, as a system, is a dream of the past. As an antipyretic,Avater may be successfully used; and it is also efficacious in certain zymotic diseases. In this case Ave had: 1. To tranquilize the irritability of the nervous system. 2. To re-establish organic functions and the vigor of the nervous system and plastic force of the blood. 3. To calm mental hallucinations. 4. To aid digestion and assimilation thus increasing the vis medicatnce naturae. 5. To disengage organic engorge- ment from crude matters and acrimonies. The support of hygiene and diet Avere not to be had, as she Avas a perfect physician's invalid, therefore had tried all sorts of diet and hygiene. A judicious medical treatment Avas the only thing to rely upon. The medical treatment Avas adopted on the principle of specific medicine : i. e., I prescribed assafaetida injec- tion for the cholichy borborysmus thus relieving the intestinal canal from the accumulation of gases and materie-morbi—and gave her R. Belladonna, 3-dec gutt. xii. Aqua distill., f ii. R. Plumbum aceti, 1-dec grs. xxiv. M. chart., xii. Dose—one teaspoonful of the liouid every hour, alter- nately Avith one poAvder. In a few days an improvement Avas decidedly taking place, for the paroxysms were not so frequent and the continuous pain and gurgling were much diminished. 192" PROGRESSIVE MEDICINE. The diet was composed of beef tea, clam broth, bar- ley Avater, eggs, broiled mutton and stale bread. Wines (old port or sherry) Avere taken as a beverage after meals. Cocoa and black tea Avithout milk. On the second Aveek I found that the medical agents had exhausted their action and that it Avas necessary to change them for R. Lycopodium, 1-dec. gutt. xxiv. Aqua distill., ? ii. R. Natrum phosph., 3-dec. grs. xxiv. M. chart., xii. j)ose—one teaspoonful of the liquid alternately Avith a powder every tAvo hours. The action of these tAvo agents is general in one, and chemico-physiological in the other. At times I had to relieve her Avith the injections, but these were only given at long intervals of two or three days. And with these principal symptoms of a gastro- enteric nature, Ave had also to consider the sensitive condition of the ganglionic and splanchnic systems of nerves. In this lady we had also anaemia, and a ten- dency to the relaxation of the whole physico-vital forces and from this tendency, an organic inertia and acidolous secretions took place. She became so much relieved that the third week she was able to sit in a chair for a feAv hours at a time. She Avas very nervous and everything, no matter Iioav trifling, dis- turbed her and felt every sensation affecting her stomach and boAvels. Her phlegmatic temperament predisposed her to ex- cessive mucous secretions, Avhich formed part of the borborysmus, being a source of fermentation; this is a great symptom of Ioav vitality. I gave her R. Capsicum ann., 6-dec gutt. xxx. Aqua distill., s h-. R. Pepsine, 3 iv. Acid hydrochl., 3 sj. Aqua bulient.. ? iv. AND PHYSICAL MENTAL LABOR. 193 These agencies Avere for the purpose of re-enforcing the process of digestion and assimilation. The capsi- cum acted upon the vagi, pheumogastric, par-vagum and solar plexus; and again, acted upon the vaso-motor, thus exciting circulation, heat, and force by its irritating elements. Surely the pepsine acted chemico-physio- logically. Dose, one teaspoonful of the pepsine after eating only. The capsicum to be taken one teaspoon every hour. All these cases of Avant of force of the organic func- tions, are to be attributed to a special time in a woman's life,e. g., the climeric time; before, during and after it. And there is the whole physical economy envolved, and anaemia is as liable to occur as asthenia. She continued to improve sloAvly but from a right source, viz., an increased physical force. Lycopodium and nux came in order on the fourth Aveek. On the fifth Aveek I prescribed R. Quinia sulph., 3-dec 3 i. M. chart., xxx. R. Arsen. alkal., 6-dec gutt. xxx. Aqua distill., f iv. Dose__one poAvder every tAvo hours alternately with one teaspoonful of the liquid. She took this preparation for two Aveeks making seven Aveeks of medical treat- ment. Her improvement Avas all that could be desired. On the eighth Aveek I gave her ferrum peroxidum and pepsine, which she took for a month; varying it at in- tervals Avith quinia and arsenic. She Avas completely cured, although she will ahvays be a delicate Avoman. This is the sixth year since she was thus attacked, and she has had no recurrence of the malady. After she Avas convalescent I had her in the air the greater part of the time. These are leading cases which demonstrate that even the most chronic ailments can be much benefited by a treatment the basis of which stands upon logic and the true principles of what compose life and force. 194 PROGRESSIVE MEDICINE. In this treatise I have endeavored to folloAV step by step the inevitable consequences of mal-assiinilation and inanition, through physical, chemical and vital dis- turbances. I have also tried to trace the pathogno- monic symptoms of the disease and its sthenic and as- thenic conditions; the hyperemia of certain organs and asthenia in others. Hyperesthesia in certain lo- calities and hyperaemia in others. It'is of the utmost importance to distinguish a general systematic disar- rangement from a local organic, or functional one. These pathological conditions might be placed in the muscular, sanguineous, or nervous system. The disorder may be centric or eccentric, ganglionic or lymphatic It might'become a brain disease or psychological phen- omena may present themselves in different degrees or phases. And again, and more frequently the excer- nent system is the part that becomes disturbed and in connection Avith the secernent the histogenetic process becomes dangerously impaired. The tripods of life are dependent upon a tripod principle, i. e., physical, chemical and vital, and these principles become deteriorated by mal-assimilation, in- anition and decay; or else they produce sanguineous metastasis, phlogosis, heteroplastic, hyperplastic or caco-plastic disorders, Avhich are maladies of far more dangerous character, threatening a perversion of plastic organization, hence incurable diseases. And more, the proteine compound, of fibrin, albu- men, and gelatin, once it becomes abnormal, the higher growth and development is prevented or perverted, and if proliferation takes place, the very germ of the cel- lular arrangement is, as it were, disseminating diseased tissue. Perfect organization of the elements of nu- trition is a sine-qua-non condition of the principles of life, whence all the dynamic forces are continually reproduced and kept in a physical state of equi- librium. And at this very point the truth of some PHYSICAL AND MENTAL LABOR. 195 great French medical observers is strikingly apparent, viz., that tuberculosis, catarrhal consumption, cancerous disorganizations, and many other similar anomalies, are the offsprings of a protoplastic perversion Avhich ends in hetero-plastic formations. These abnormalities are not exclusively congenital, for they are often acquired by many and various causes, and surely mal-nutrition must be at the topmost, proceeding from Avhate\Ter ex- citing or predisposing cause, remote or proximate. I do not mean at the same time to undervalue diathesis and congenital inheritance, but I am decidedly of the opinion that the majority of diseases are acquired either by exposures, confinements, occupations, effluvia, or traumatic causes. If the process of reproduction is not adequate to the Avaste, or does not supply the ele- ments required, nutrition must be at a loss, and the great phenomenon of life in peril. The vis-vitae and nisus formations go through a pathological metamor- phosis, and hence disease. From these axioms, as established principles, Ave must rationally accept, that, the true and best therapeutics are based upon the elementary principles or formation of a perfect plastic matter; and to bring about a physical or physiological change, Ave must adopt those means of Avhich nature is in need, and by Avhich the vegetative process of life is kept up. Are Ave not to derive more hope from such a natural source, than from artificial agents Avliich are often uncertain in their influences, and oftener too superficially knoAvn for their direct thera- peutical effects. The lymphatic system is the process of physical development (tissue-making) from an histo- genetic principle, the materials of Avhich are albumi- noids and amyloids, these must be in an acceptable condition; in other Avords, they must be thoroughly assimilated for further organization by the lymphatic vessels; but Avhen, as often happens, in diseases of the digestive organs, such an assimilation is not per- 196 PROGRESSIVE MEDICINE. feet, either of the nitrogenous nutrients or the albu- minous, Avhat is the logical conclusion ? Three pathological conditions may arise, \'iz., adynaemia, hetero-plastic formations or asthenia, and these may produce a variety of diseases: malignant or not. Malig- nant, organic, functional, general or systemic ; also, leucothemia, struma, exanthem, arthritis ; hepatic troubles and consumption; portal engorgements; atrophies and hypertrophies; neuralgic and renal diseases. Scrofula, spuria or A'cra, and zymotic disor- ganizations. I often observed that phthisis proceeded from dys- crasia in the blood, the result of mal-assimilation of the albuminoids or nitrogenous nutrients, and this takes place from lymphatic Aveakness or defective digestion; thus devitalizing the quality of the animal nutrition. The blennorhagies, pulmonic or intestinal, tabes-messen- terica, gastrosities, apepsia, adenitis and cretenismus originate frequently from the above source. The ductus aquosi of the old Avriters conveys precisely the idea of obstructed channels, thus rendering absorp- tion defective and nutrition impeded; these lymphatic vessels pervade the Avhole economy, and Ave can readily imagine the results Avhen such physical arrangements are disordered. Therapeutics is at a loss in these chronic and constitutional cases, for they require much time and acumen for the process of restoration. The first in- tention should be to ameliorate the most salient difficul- ties and strengthen the lymphatic system ; correct crudities and Avaste of animal vigor and pacify nerA-ous irritabilities or mental agitation. Then forAvard to a radical treatment on the basis already described. I deem it desirable noAV to bring fonvard a different class of cases Avhich Avill demonstrate practically the result of lymphatic diseases, inherited and acquired, and PHYSICAL AND MENTAL LABOR. 197 the predisposing and exciting causes, remote as Avell as proximate. CLINICAL CASE VI. During the year 1869 I AATas called to see a lady thirty years of age, Avhose life had been mostly passed in the country upon her father's farm. Her domestic life had not been a happy one on account of family differences Avith a cross step-mother. She Avas very sensitive and high-minded, Avith a pur- ity of heart seldom found. She Avas raised among the hills of Ohio, and it had not been her lot to come in con- tact Avith the hardships and corruptions of the Avorld. Her step-mother Avas the reATerse: she Avas a smart, cal- culating, intriguing Avoman, Avhose heart and soul Avere devoted to one ideal son. She became harsh to the poor girl's father, Avhich Avas a great source of grief and productive of family-quarrels between them. These irritating circumstances Avere indeed preparing the Avay to some physical complications, as it finally proved. Some fifteen years before I saAv her, she took Avhat she called a cold, and Avas sick Avith an attack of pleuro-pneumonia resulting from it. She had a very fair complexion—rosy cheeks, prominent lips, light blue eyes, large head, and a small frame. She had ahvays been delicate, and eminently a small eater, Avhich is rather unusual Avith diealthy country people. Physical Examination.—Her chest looked contracted, respiration 28 to 30 to the minute, temperature 100; pulse 110 to 120, On percussion, I found dullness in both the loAver half of the lungs Avith actual tubercular infiltration. She breathed only Avith the upper third of the lungs. Auscultation discovered bronchial mucous rales, extending doAvn to the smaller branches, the bron- chioles. The bronco-pneumonic difficulty gradually increased. I also found a cavernous sound about the lower half of the right lung Avhere the tubercles were breaking doAvn. 198 PROGRESSIVE MEDICINE. The voice Avas tremulous, (aegophony) Avith a mucous- ronchus audible even at the outside. She coughed in- cessanth', and the expectoration Avas of a muco-purulent character. She suffered Avith night sAveats and turned against food. Her pulse increased from ten to fifteen degrees every afternoon, Avith full pyrexia,profuse perspiration, and increased cough. She Avas much flushed and pros- trated. These paroxysms Avould last till ten o'clock p. m., and the temperature and pulse Avould return almost to their normal condition about three o'clock in the morn- ing, and remain so till about 12 in., Avhen a certain cli- max had arrived, and both temperature and pulse Avould rise again. Semiology.—The symptoms of consumption have been so ably described by those avIio have made a specialty of lung diseases, that any attempt of mine for such a purpose Avould be futile and pedantic. She had regu- lar evacuations of the boAvels, regular menstruation and pain in the chest and insomnia. She improved in the spring and during the summer months, but the same condition of things returned again, as soon as the ther- mal temperature changed. The idiosyncrasies of the case Avere: 1. Infiltration of the loAver half of the lungs Avhich Avas never extended above that line. 2. A vomica, Avhich did not appear to increase in size. 3. Regularity of menstruation to Avithin three Aveeks of her death and natural evacuation of the boAvels. 4. The regular pyrexia and length of the disease being of fifteen years standing. Her mental faculties, Avhich Avere clear and good to the last, only gave evidence of slight delirium during the febrile state. Etiology.—The causes Avere both inherited and ac- quired. Her lymphatic diathesis predisposed her to blennorhagia and subacute hyperemia and metastasis of the glandular system. Her unfortunate domestic troubles acted as an exciting cause; and an irritability PHYSICAL AND MENTAL LABOR. 199 of the nervous system increased ten-fold the hyper- aemic predisposition of lung tissue. It is clearly perceptible that it Avas a case of hetero- lymphoma Avith caco-plastic deposits in lungs; it Avas a disease of the lymphatic vessels and glands, Avhich dis- seminated its acrimony to the lymph, hence impure blood, devoid of fibrin and containing an excess of se- rum and crude Avhite corpuscles. Medical Treatment.—It Avas necessarily symptomatic and palliative. I used lactuca Avith some advantage, and calcarea caustica to diminish the excessive expec- torations. Phosphate of arsenic Avas given Avith much benefit ; and also the liquor-potass-arsenicalis of the old school in minute doses, viz., 6-dec one drop to a teaspoonful, to be taken every two hours. Sponging Avith salt and Avater morning and night. I used senegar, tincture of prunis virginiana, Avith some benefit. Belladonna and aconite Avere frequently given during the pyrexia. She died, after a long illness, in peace and Avithout pain. CLINICAL CASE VII. A young lady, tAventy-nine years old, of slight frame, light complexion, and of a nervo-lymphatic diathesis, Avas obliged to work in a factory (India-rubber). She had blue eyes, light hair and fair skin. She did not have the pathogonmomic symptoms of struma, yet she Avas of a delicate fibre and lacked-physical and vi- tal vigor. Her blood Avas thin, and her Avhole constitution de- noted a tendency to emaciation and adynaemia and lym- phatic Aveakness. She had pronounced indications of consumption. The greater part of her life had been passed in the factory, Avhich Avas very close, Avhere the air Avas mephitic Avith an accumulation of gases destruc- tive to the animal economy. 200 PROGRESSIVE MEDICINE. The nutrition Avas defective caused by a poor diet. Her business prevented her from taking that exercise so necessary to the process of re-organization and thorough decomposition. Assimilation Avas imperfect and the recuperative poAver of nature Avas gradually on the decline. No Avonder that a principle of disorgani- zation Avas implanted in her system. Physical Examination.—Chest small but regular in shape; there Avas no depression visible. Breathing ac- celerated to 40 a minute. Pulse 101 to 102. Tempera- ture high 99.^- under the axilla. On percussion I found dullness over both lungs, es- pecially so over the right. Auscultation revealed bron- chial respiration Avith crepitant rales, and decided hepatization over the Avhole right lung, and tAvo-thirds of the left- There Avas no sonorus-ronchus or vomica. The voice Avas feeble and metallic, rebounding against the hard tubercular surface of the lungs. Expiration difficult and quick, having no volume of air to eject and a very little diaphragmatic force to contract upon the chest, in order to expel Avhat little air there Avas. There were Avheezing sounds here and there. Egophony Avas clearly perceptible. Heart quick and feeble in action. Liver sound and kidneys normal. Skin moist Avith a sour smell. Offensh^e breath. Pain on percussion. Tongue tremulous and Avhite. Nails inverted. Hands hot and emaciated. Semiology.—Cough dry, and after Avith a great effort she Avould raise a hard ropy mucous Avith a hard nucleus. It Avas undoubtedly a glandular secretion looking like crude albumen. Under the microscope I discovered many nucleoli of lymphatic cells. She suffered Avith apepsia, insomnia, night SAveats and constipation. Her menses ceased. Hyperaesthesis, and asthenia Avere prominent features of her temperament. Her mind Avas constantly preoccupied Avith the idea that she Avas be^- PHYSICAL AND MENTAL LABOR. 201 yond cure. She had had a terrible love-disappointment which preyed upon her mind constantly. The signs Avere unfavorable indeed, and the prognosis could not be hopeful. The Avhole physical economy AATas sloAvly becoming Aveaker and inanition Avas impending. She lacked not only physical force but vital and men- tal, therefore I Avas sure the case Avould end fatally and to that effect I gaA"e my undisguised opinion. Diges- tion and assimilation Avere disordered so that the pro- teine compound Avas defective in quality and quantity, and. consequently the process of histogenesis Avas im- perfect, reducing the system in force and development. Etiology.—The predisposing and proximate causes Avere inheritance, poor diet, ovenvork in close, unhealthy atmospheres, and physical inactivity in the pure air. The exciting and remote causes Avere asfolloAvs: 1. Inability in aiding the great process and metamorphosis of decomposition and re-organization; this alone Avas a radical defect in the vegetative Avork, hence adynaemia. 2. Mental excitability and unsatisfied desires. 3. Want of proper bathing and disregard of exposure. These numerous physical deteriorations increased to a con- siderable extent her liability to pulmonic consumption. Atrophia and hetero-plastic lymphoma Avere the results of an inherited and induced defective chylification and hence histogenetic difficulty. Hygiene and Dietetics.—The case Avas too far advanced and the pathological condition of the lungs too Avell set in to hope much from any treatment. I prescribed bathing in alumina baths, thus diminishing capillary congestion and reducing both temperature and night SAveats. The diet Avas generous—composed of beef tea, clam broth, eggs, wine and eggs; wine soup, beef steak, roast beef, birds—in fact mostly nitrogenous food. Cream, fruits and nitrogenous vegetables. A hard bed and driving in the country. Medical Treatment.—\\T hat shall we hope from our 202 PROGRESSIVE MEDICINE. materia medica in these desperate cases ? I Avish I could say much or even considerable, but I regret to say that little can be expected, although much benefit and comfort can be given to the patient. R. Calc phosphorica, 3-dec. 3 i. M. chart., xxx. R. Senega, 1-dec. 3 sj. Aqua distill., f ii. Dose—one poAvder every hour alternately with a tea- spoonful of the liquid. The cough diminished in fre- quency. The expectorations Avere less tenacious or ropy and more fluid. There Avas a diminished disinteg- ration of the nucleoli of the lymphatic glands. The hygienic, dietetic, and medical treatment all combined, Ave re conducive to a general improvement, but none the less the progress of the disease Avas checked to no ap- preciable extent. I gave her kali arsenicalis, Bella- donna, Bromine, iodine, cod liver oil andBarita carbonica, phosphorus, etc. But AA'ith the exception of temporary improvement the patient gradually greAv feebler until her miserable existence ended. I must say that she had the usual afternoon and night pyrexia Avhich caused insominia. The lactuca, belladonna and aconite relieAred all those symptoms. And especially in this case, she being so young. I am strongly inclined to believe that if she had been raised in the country and witli light field Avork, early hours, simple good diet, quietude of mind the probabilities Avould haA-e been an entire re-invigora- tion of the recuperative and plastic forces, hence more development and the atrophia lymphatica corrected to a great extent. CLINICAL CASE A'TII. Mrs. L., of Gambier, Ohio, forty-three years old, of lympho-phlegmatic diathesis. She was large in frame, had blue eyes, white skin, large mouth and thick lips. Blue veins Avere visible PHYSICAL AND MENTAL LABOR. 203 under the delicate skin. She Avas \Tery intelligent, good natured and of a strong Avill. She married late in life and had no issue. She had been an invalid for many years and tried a great many physicians Avith but little relief. Her general appearance Avas good and strong, yet she suffered Avith cough, night sweats, pain in the chest and general exhaustion. Her ambition and industry Avere unbounded. She lived Avell and had the comforts of a home. The climate at Gambier is moist and changeable and her life Avas very retired and devoid of air and motion. All her Avork Avas in close rooms, comprising domestic duties. Physical Examination.—Her chest Avas avcII developed and considerable volume of air seemed to enter, yet on long inspiration the lungs did not take up the normal quantity of air that such an exertion Avould naturally suggest, and the expansion of the chest seemed insuffi- cient. There Avas no diaphragmatic respiration, but prolonged expiration, as though the air inspired could not easily be removed. Auscultation revealed moist crepitous ronchus over'the bronchia and bronchioles, Avhile over the rest of the lungs there Avas aegophony; the voice rebounding back and a sibilant sound Avas heard here and there, Avhich are sure signs of hard hepatization. I found this con- dition particularly in the right lung, on its upper third. This indicated bronchial respiration. There Avas also a cavernous sound in one spot, but I could not discover any gurgling noise. The loAver lobes Avere hepatized. On percussion, I found dullness under the axillae all the Avay down to the apices. Supra-clavicular dulness— over the clavicle and over the upper lobes no real hepatization could be discoA'ered, yet there Avas a muffled sound not reassuring. There Avas much bronchial expectoration of clear mu- 204 PROGRESSIVE MEDICINE. cous Avitti, at times, a nucleus of hard gray tubercu- lar-looking substance in the centre of the expecto- rated matter. On microscopic examination I found these little hard substances to be a mal-assimilated fibrino-nuclieted lymphatic granules, leading me to believe strongly in their proliferation by contact thus disorganizing the lung tissue and glandular arrange- ments. The temperature of the lungs Avas 99g. Pulse, during the afternoon, Avas 112 to 120 and hands and feet burning hot. Her finger nails Avere turned iiiAvardly. Heart sound; liver in good condition, kidneys normal. Her digestive organs Avere in a state of perfect torpid- ity. Night SAveats and arterial hemorrhage. Semiology.—I found her Avith a dry hacking cough Avhich, by much exertion, brought about large bronchial yelloAvish mucous expectoration. This effort exhausted her very much. She Avas suffering Avith apepsia, in- somnia and apyrexia from early in the afternoon till midnight, Avhen she found some rest. Great mental dis- turbance causing dreams and seeing all sorts of spectres. Assimilation difficult, circulation feeble; blood thin and Avatery. Her idiosyncrasis Avas hyper-lymphoma or mal-assimilated albuminoids. Menstruation regular at times, and at others abundant and painful. At times she suffered Avith complete aphonia for days, and it un- doubtedly proceeded from great nervous debility of the pneumogastric and pharengeal plexus. The hemorrh- ages Avere often serious and enfeebling vitality, Avhich she needed to a great degree. With all these un- pleasant prospects she Avas rather cheerful and kept up a Avondcrful amount of courage. Etiology.—Inheritance and crude lymph. Exciting causes Avere only confinement to the house. No other difficulty could be traced than Avant of motion and de- composition. Jfcdicul Treatment.— The laws of dietetics and hygiene PHYSICAL AND MENTAL LABOR. 205 as re-invigorating and vitalizing elements Avere Avell knoAvn to her and she had adhered to them faithfully. I have no doubt that the highly nitrogenized food and the liquor diminished the progress of decay and kept up as it Avere an artificial force, and thus she Avas under the restorative principles of life, minus a feAv other agencies, which if they had been employed earl}T, organization Avould have been fully established and strengthened. Air, out-door exercise, and mechanical labor in the garden AArould have brought about results of vitalization that no other means supply. The medical part of the treatment Avas palliative, for it hardly could be called curative in that stage of the disease. R. Calc. phosphorica, Ferrum peroxidum, Liquor potass., Arsenicalis, Secalae cornuta, Natrum phos- phoricum, Senega, Prunis virginiana, Lactucaria, Phos- phorus. Inhalations of carbolated lime, stopped the excessive secretions. I finally succeeded in sending her to St. Diego, Cal., Avhere she could enjoy the benefit of that beautiful and thermal climate. AfeAv months after she reached her place of destina- tion I heard tnat she had improved Avonderfully that she had groAvn stout, coughed little and Avas generally invigorated. CLINICAL CASE IX. A young man, thirty-one years old, of a delicate phys- ical development, Avhose occupation Avas packing and drying tobacco in a snuff factory, Avhere that material Avas constantly afloat and therefore inspired through the nose and lungs. He sent to consult me for a severe sore throat. His general appearance presented at once that of long physical suffering and complicated disease. He had blue eyes, light complexion, and Avas of a nervo-lym- 206 PROGRESSIVE MEDICINE. phatic temperament, hence predisposed to those ailments of Emphatic constitutions. I found him lying in bed, Aveak and prostrated, suffer- ing from aphonia and night sweats; small, quick pulse and general physical debility indicating vital disarrange- ment. Physical Examination.—There Avas nothing irregular in his physical construction; respiration regular, though too frequent (22 to the minute). He Avas greatly ema- ciated and feeble. On auscultation I found respiration and expiration natural and no abnormal sounds percep- tible. Percussion did not reATeal any pain or dullness. I could not discover any pathognomonic signs of phthisis either incipient or chronic The heart's action Avas quick and regular, but Avanting Arolume and firmness. His boAvels Avere constipated; liver inactiA'e but not enlarged. Stomach seemed to perform its functions naturally; appetite capricious, a desire for coarse food, like fried ham and potatoes. Semiology.—Ho coughed constantly at night, and could get no sleep. He said, "Oh! Doctor: if I could only sleep! " He did not knoAv his condition; he thought it Avas simply a difficulty of the throat Avhich could easily be overcome. He Avas a poor man, and lh^ed in badly ventilated rooms, croAvded Avith dirty children. His food had ahvays been of an inferior quality and miserably cooked. His ignorance of the proper rules of living and hygiene exposed him to discomforts and physical suffer- ing. Undoubtedly his occupation Avas conducive to dis- organization of the respirator}' apparatus. I found him expectorating a large quantity of ropy mucous, containing solid mucous membranes, Avhich had the appearance of having been detached by ulceration. The urine Avas high in specific gravity and did not con- tain the usual amount of phosphates. Hyperemia, Avith a hot, burning skin. Great thirst and a constant scrap- ing of the throat. His difficulty commenced a year or PHYSICAL AND MENTAL LABOR. 207 so before and he had had some medical treatment from the Allopathic school, Avhich he described as nauseous and disturbing his stomach. Cod-liver oil and Avhiskey Avere also given, but Avith no apparent benefit. He continued to Avork in the snuff factory until his strength Avould alloAv him to do so no longer. No regular diet Avas prescribed nor hy- gienic rules; he Avas left to his sad fate. His voice Avas changed into a hoarseness, mixed Avith some sybillant notes, strongly indicating a changed physical condition of the larynx—he felt a lassitude Avhich denoted a deep seated disease. The larynx, on examination Avith the laryngoscope, Avas found Avith spots of ulceration through the mucous coat, extending doAvn to the trachea, and perhaps doAvn even to the biforcation of the bronchi. There Avere no signs of tuberculosis in the lungs, though I suspected such condition in the trachea and larynx. Etiology.—I could learn nothing of his inheritance, as throAving any light upon the diagnosis of the case. His parents Avere all dead, and according to his account, died young and not of consumption. But as usual, Ave are sadly disappointed if Ave place much reliance on such desultory accounts, for they are generally disconnected and unsatisfactory. It Avas sufficiently eA-ident that they Avere poor and belonged to that unfortunate class, the loAvest strata of the human family, full of vices and ignorance ; improvident and neglectful of the first princi- ples of life and its requirements. These people leave the seed of their vices to their offspring, there to groAV and develop. Unless these poor children of misfortune are removed early in life to salubrious climates and better modes of living, and raised by education to understand the importance of proper attention to the rules of life, they are apt to die youn0, Avith sdme discrasia implanted by their fore- fathers and developed by their neglect. 208 PROGRESSIVE MEDICINE. In this case, I should express my conviction that both inheritance and occupation Avere the tAvo principal fac- tors Avhich prepared the foundation of this pathological condition. And besides, Ave had the exciting causes of poverty, Avant of hygiene, exposure, ovenvork and bad and improperly prepared food. We could classify these cases together Avith consumption, lymphoma, ra- chitis and scrofula in all their varieties and forms. Treatment.—In these cases of physico-vital disorgani- zation all authorities have found that our art is deprived of those very elements upon Avhich Ave can build Avith any hope of success. The material necessary to Avork Avith is not any longer to be found or trusted. The or- ganizing principle being once vitiated, the correlation of the physico-vital forces is impossible. I prescribed baths of iodide of potassium Avhich had the beneficial effect of stopping the night SAveats and the excessive expectoration—and besides I ordered: R. Kali causticum, 6-dec gutt. xxiv. Aqua distill. * iv. Dose.—One teaspoonful every tAvo hours. He Avas kept on this treatment for a Aveek, but Avith the exception of having recovered a little strength, Avhich I credited to the potassium, no other improve- ment Avas visible. In my perplexity I gave him the doubtful benefit of a change: R. Acid nitricum 3-dec. gutt. xxiv. Aqua distilt. f iv. Dose.—One teaspoonful every tAAro hours. With this I gave him baths of nitro-hydro-chloric acid. For a Avhile his expectorations improved, his appetite returned to its normal condition, his bowels moved reg- ularly, and he slept better. Like every physician Avhose hopes from the very first are disheartening, this im- provement kindled a spark of hopeful anxiety, that after PHYSICAL AND MENTAL LABOR. 209 all something could be done with this young man. In connection with the treatment I gave him a generous diet composed of the most nutritious elements, such as roast beef, rare mutton, Q'-g^, milk punch, clams, rice, beans (black), generous soup, wine, black tea with cream, three times a day, in order to prevent the great Avaste going on; finally I exhausted the dietetic list. The treatment benefited him only for two weeks, after which he became weak and despondent; the cough re- turned as bad as ever, and in fact all his former bad symptoms reappeared. Ho suffered with great dyspnoea and pain in the trachea. I relieved him with a feAv drops of hydrocyanic acid in milk. Borax Avas also given Avith temporary benefit. He finally died suddenly. Of course my patient Avas too far gone when he came into my hands, and there Avas no time for treatment sufficiently exhaustive to pronounce homoeopathy a failure, for other remedies should have been tried before reaching such a conclusion; yet I feel that these cases defy all our art—at least mine. Rationally speaking, does our case suggest to us that there might have been a prophylactic medical treat- ment which might have produced a change in the phy- sical predisposition of this man? Could our profession offer any reasonable hope of disengaging the system from those crudities of perverted lymph and changing them into a healthful organizing process? Unhesitatingly I ansAver, that the majority of these weakly constituted people, if the proper hygienic and dietetic rules could be enforced early in youth, and they removed into a salubrious country life, working on farms in the open air, probably ninety per cent, would be successfully cured and the predisposition eradicated, or so modified, that a long life would be secured to them. 210 PROGRESSIVE MEDICINE. CHAPTER T. DISEASES OF CHILDHOOD. DEFECTIVE ORGANIC AND VEGETATIVE FUNCTIONS. Organic force and its physiological functions depend upon a triple cause or origin, viz.: physical, vital, and mechanical, and it is obvious that the vegetative cliemico-physiological functions are derivath'es of this natural combination of the physical organization. The systems of absorption, secretion, circulation, excretion, etc, are all included in this vegetative and primitive vital action. We will find the division of the lymphatic system into internal and external, useful, being connected by anasto- mosis of large plexuses. This system is entirely con- fined to animals, for it is not found in either birds or fishes. It is sometimes irregularly developed in its plexuses, but mostly found in the tract of the absorb- ents connected Avith the lacteals and lymphatic glands. These absorbent vessels are found mostly on the in- ternal surface of the small intestines, and visible only by a poAverful microscope. They are found larger, as they are intended for stronger physiological functions. The age of infancy is unquestionably a period merely of nutrition and groAvth Avith all its concomitants, acci- dental or otherAvise, and disarrangements and diseases. This complex Avork is evidently accompanied by many difficulties, the organs of digestion and assimilation be- ing taxed to the utmost in the process of organizing (or preparing), assimilating secretions, and selecting the dif- DISEASES OF CHILDHOOD. 211 ferent requirements, and at the same time expunging the materials Avhich have ceased to be useful and nutritive; and it is also natural that the vital functions should be heavily engaged in assisting in this physico-vital pro- cess, hence the occasional hyperaesthesia of the ner- vous centre (brain) running oftentimes into irritability, hyperaemia, and asthenia. Excessive nutrition is truly oftener the cause of diseases of the vegetative system of infants rather than a Avant of it. The Avatchful and unwearied mother is too frequently the innocent source of implanting obstructions to the groAvth of her child by overtaxing his or her digestive functions. The lymphatic system has such a material iufluence in the process of physical organization, that I Avould venture to say that in the majority of diseases Avhere atrophy, asthenia, anaemia, and marasmus exist, Ave Avill find atrophia lymphatica, adenitis, hyper-lvm- phoma or hetero-plastic lymphoma. By these various pathognomonic indications avo are able to trace the na- ture of these abnormalities, originating from idiopathic, symptomatic, acquired, inherited, predisposing, or ex- citing causes. And, furthermore, these pathological differentiations lead us to a more intelligible knoAvledge of these diseases and their treatment. At this peculiar period of infantile life, avc may Avell say that the animal economy is not guided by the Liav of equilibrium, as the process of nutrition must necessa- rily be far in excess of that of Avaste, and therefore the chylopaetic A'iscera must be strong enough to prepare, assimilate, select and separate the nutrients, in order to retain the necessary physical force for the histoge- netic process. The fats, the acids, the urea, the triplo- phosphates. etc, must be electively selected in order to provide the plasma Avith those elements necessary for the accomplishment of the grand ensemble of animal life. We have clear and logical evidence that all the or- 212 PROGRESSIVE MEDICINE. gans must be in a state of very great active turgescence (orgasmus) and this must be continually and promptly removed by organic force and activity, and conse- quently, it is easily understood that the process of chyli- fication can be readily changed from the normal into an abnormal condition, both in quantity and quality; and thus being subject to become either a nutritious or a non-nutritious element, from Avhich life and force are attained; or, vice-versa, debility, atrophy and decay. The lacteals and A'illi select, their formative elements, and the rest is reabsorbed by the lymphatics to be reorganized and carried again through their vessels into circulation and contact Avith the glands, and there to be acted upon by a lymphatic fluid until it becomes a suitable element for tissue and blood. These great glandular arrangements act physiologically upon the albuminoids and oils, so that these elements may be properly prepared for general nutrition. The pancreas, Brunner's glands, Payer's patches, and all the enteric fluids are Avell knoAvn to possess this physiological property. The superfluous material, of course, is taken in charge by the excreting organs. The glandular system in childhood is naturally larger and softer, than in advanced years and its external ganglia is easily felt by the naked hand. This condition remains as long as the system needs such a great amount of nutrition, and decreases step by step as Ave advance in age, till the Avhole system reaches the acme of statu- quo and gradually descends into inanition and natural decay. It is of much importance to be able to diagnosticate the various shades of lymphatic diseases and their path- ological differences and general effects. Hetero-plastic lymphoma is detected by general scrofula, and is the physical result of an acrid, ichorous lymphatic fluid, the true evidence of mal-assimilated albuminoids, Avhich, form into the abnormal fluid above described, and is the DISEASES OF CHILDHOOD. 213 result of many pathological lesions, viz., eczema, ecthema, scrofulous ophthalmia, tetters, marasmus, adenitis, acne, lupus exedens et non-exedens, intertrigo, porriga, crusta lactea, otitis, tubercolosis, ulcers, tumors, etc We designate cases of hyper-lymphoma in fatty lymphatic persons, by superfluous animal tissue, added to easy good nature and indolent disposition, Avhere the ner- vous system is in a certain sense, sIoav to act and lacks vital force. If this temperament or idiosyncrasis is happily en- doAved Avith strong nervous and sanguine force, it is un- doubtedly an addition of great value; but of course an excess of either, Avould predispose an individual to some peculiar malady of its own peculiar kind, and thus lose that equilibrium so necessary in a perfect organization. In hyper-lymphoma Ave frequently find a serous blood, leucophemia, and a proneness to tumors, catarrh, pulmonary difficulties, Ioav fevers, etc. We also often find the reverse of this condition Avhicli is known as lymphatic atrophy. This abnormal condition may be inherited or acquired; it may also be a mere constitu- tional idiosyncrasies or a result of mal-nutrition, malarious influences, or other diseases peculiarly devitalizing. When such condition is congenital, there is no doubt of its being the result of an ichorous lymph—(hetero- plastic) and hence abnormal lymphatic development such as atrophia lymphatica, or marasmus; and in this instance the histo-genetic process is necessarily abnor- mal. The chyle may be properly and sufficiently healthy, but the moment it has to enter into a further stage of animalization by entering the lymphatic ves- sels and glands, it finds hardness, insufficient vital and physical force, and the fluid secreted becomes of a disor- ganizing rather than organizing nature. This physical defect changes the healthy chyle into an abnormal fluid and from that, the blood becomes deficient in fibrin, in iron, in phosphates and naturally, the liquor sanguinis is feeble and serous. 214 PROGRESSIVE MEDICINE. In cases of acquired disorder of the lymphatic system, there is more hope, and less tendency to malignant and incurable disorganization. It may be a temporary and superficial derangement, in which with care and proper hygienic and dietetic treatment a favorable change may be produced. It is in this acquired atrophy that the intelligent physician can prevent much mischief and re- establish a physical equilibrium, and thus conquer a disease Avhich if neglected, or not intelligently treated is sure to create organic hyperaemia and nervous asthe- nia, finally ending in adynemia and constitutional decay. The principal train of symptoms are emaciation, mental feebleness, enervation, apepsia, renal troubles, hepatic engorgement and atrophy; Aveak venous circu- lation, rachialgia, curvatures, morbus coxalgia, and follic- ular diarrhea, general cachexia. In this last instance nutrition is at a high degree of insufficiency. The chyle must be (as a sine-qua-non) deficient in those prop- erties required by the general system: the nitrogenous, albuminoids, calorificients, one and all, divested of proper animalization, hence mal-nutrition; and therefore the physical metamorphosis Avill sooner or Liter retrograde into a condition of general disorganization. Exciting causes are : Exposures, poor alimentation, un- cleanLness, excess in eating, drinking spirits, excess in venery" Avant of proper hygienic rules, confinement in prisons, bad Avater and abstinence from animal food. Also, sedentary life, and living in unhealthy low loca- tions Avith effete exhalations. There are likeAvise cer- tain diseases Avhich invariably excite numerous gangli- onic complications, A'iz., measles, intermittent fever, scar- let fever, typhoid and typhus feArer; also chronic diar- rheas or dysentery; ship fever, erysipelas, small pox, syphilis, gastro-enteric engorgements, mal-assimilations, typho-malarious fever, and suppurating Avounds. There are an infinite number of causes that are liable to irri- DISEASES OF CHILDHOOD. 215 tate this delicate ganglia, and its relation to the venous system renders it liable to communicate its morbid ef- fects to the venous circulation as the lymphatic vessels end, Avhere the venous begin. It is unquestionably a physical disorganization, Avhich necessarily affects the pabulum vitae and plastic force. The lymphatics being divided into plexuses are not only placed in different parts of the digestive track as co-operating Avith the process of animalization of chyle and lymph, but they occupy also an important place in the excretory apparatus as Avell as in the absorbent; they form conclusively a process of injection and ejec- tion. Through the apparatus of the skin the outside influences are received. Through it, Ave receive the depressing and devitalizing influences from animal and vegetable decay, viz., that of mephitic gases, malarious effluvia from marshes of fresh or salt Avater; through it Ave receive the morbific influences from meteorological changes—the ever increasing or decreasing elements of health and life: the thermal temperature giving us a genial atmosphere, or a cold Avind, chilling us to the very marrow and carrying Avith it dampness, Avhich ab- sorbs animal heat faster than Ave can re-produce it, thus producing those diseases peculiar to a sudden change of air, impregnated with moisture. Daily changes of temperature engender pulmonary disorders, rheumatisms, neuralgia, hyperaemia and phlogosis, all of which have a tendency to lower organic force. We have evidences of this in that dreadful scourge which rages in the south—the yellow fever, and in the meteorological influences in the time of cholera, and typhus diseases. We have evidences noticeable in en- teric troubles of children and all these materie-morbi are brought imvardly by the lymphatics. This, together Avith breathing infected air, and the everchanging evaporization of the body, predisposes the animal economy to an innumerable number of dis- 216 PROGRESSIVE MEDICINE. arrangements and diseases. An excessive evaporation of the body caused by atmospheric heat or produced by an undue amount of activity, predisposes one to pyrexiae and phlogosis. If, on the reverse, evaporization should be suddenly checked, the urea, the biliary matter, the lactic and carbonic acids are not eleminated, hence Ave have all that train of infantile enteric disorder Avhich every physician is acquainted Avith. Thus it is an un- deniable fact that the lymphatics Avithout, as Avell as those Avithin, have the most intimate relations in the function of absorption, secretion and excretion, besides that of organization. These various atmospheric causes bring about an irritability of the lymphatic vessels, a change in the digestive fluids becomes unavoidable, and hyperaemia lymphatica Avith pyrexia and turgescence follow. En- tero-mesenteritis takes place, Avhich is noAv-a-days ex- pressed in the generic term of cholera-infantum. This condition must bring about an abnormal change in the functions of the chylopoietic viscera and therefore in the nature of the chyle itself. The first condition is generally that of plethora lymphatica followed by irrit- ability, asthenia and adynaemia Avith exhaustion. The derangement of this important system reflects, oftentimes, its poAverful influence back upon the nervous system, the blood, and the functions of the organs. And therefore Ave have the discrasie, the cephaloid troubles, and organic maladies. And in this country Avhere the meteorological changes are so deleterious to health, Ave are seriously affected, and particularly the children, from these elementary causes. The air of our cities is liable to be impregnated Avith mephitic gases; that of the country Avith malarious poison arising from veget- able decay or paludal effete exhalations. But on the contrary in high mountainous air Avhere these poisons are not to be found there are seldom such diseases preva- lent. DISEASES OF CHILDHOOD. 217 The process of digestion and organization is obviously attacked by all diseases proceeding from either malaria, mephitic, or effluvial exhalations. The vital force is at once struck at its very base, the chemico-physiolog- ical process is changed and the Avhole physical organiza- tion becomes infected and modified. Is there any great difficulty to imagine such metamorphosis? and although Avell understood it is not ahvays in our power to change these conditions, and by a negative action or apathy great epidemics are produced and spread, which become uncontrollable even by the best medical skill. The precursory symptoms are those of general mal- aise, Avant of appetite, insomnia, Avhite coated tongue, dry hot skin, hot breath, prostration, diarrhea, strong and small quantity of urine, Avant. of mental force Avith irritability, the pupil becomes dull, the pulse quick and at times irregular. The cardiac symptoms are either sIoav and regular in action, or irritated by a quick jerking pulsation, The organs become inactive, and the secretions are sIoav, and limited in their functions. Gastro-hepatic torpid- ity, and gastro-enteric inactivity are necessarily the prelude of a physical disorder. And if these prelimin- ary ailments are not either, by nature or artificial med- ication checked, the disarrangement proceeds further and gradually affects organic action; the nervous centre and blood are by progression sympathetically or vitally subordinate to morbific influences Avhich disseminate ac- rimonies crudities and disarrange further organization, assimilation, chylification and nutrition. The distinction between simple dental irritation and meteorological changes should be a sine-qua-non with the physician. And again, betAveen over-nutrition, causing plethora irritability, and digestive crudities, or insuffi- ciencyof the proper food in quality and quantity, are also matters Avorthy of serious inquiry. There must be properly ventilated apartments, bathing, and careful 218 PROGRESSIVE MEDICINE. attention to the bed and clothing. Often times the ori- gin of this infantile trouble is due to the Avant of the first rules of hygiene and nutrition. Another great con- sideration for the general result is, Avhether the mother's milk and diathesis is to be a source of strength and health to the infant, or AAdiether an artificial nutriment would be more advisable. 1. Consumptive or scrofulous mothers should not nurse their children as any discrasia of the blood can be communicated and increased by the daily process of nu- trition. Children of such parents should be nursed by healthful Avet-nurses and enjoy the strengthening reno- vating physical influences of country air. 2. An analysis of the milk should be made in all cases Avhere the infant appears to ail from abnormal nutri- tion; there Ave may find the real cause of the disturb- ance. The milk may be too rich in butter, or casein; it may contain a strong lactic acid, or abound in case- ous substances; else not contain a sufficiency of al- buminous substance. If the proteine compound is at all abnormal, the his- togenetic process becomes impaired in its very first principal of life. In finding these difficulties Ave must have the remedy at hand. 1. A very suggestive one is condensed milk; 2. Experiments have proven that a vegetable compound of nitrogenous food can be safely and scientifically supplemented (vide leguminous food); 3, Purely animalized food in the shape of mutton broth, light beef tea; broth and vermicelli; broth and bread Avell boiled and strained. I have a strong faith in rice, peas and lentils as substitutes for milk. These artificial nutritions are more frequently a tem- porary necessity, but sometimes it becomes an imperi- tive one for months and even years. We have a remedy in changing animal to vegetable nitrogenous food, avoid- ing the amyloids and the carboniferous, adding only the succulent by giving the ripest fruits with sugar. DISEASES OF CHILDHOOD. 219 Every physician should have a lactometre thus measur- ing the amount of Avater. It should not be forgotten, that each diathesis has an idiosyncratic inheritance, and that idiosyncrasies should not be alloAved to become the prominent feature of the system, thus necessitating the loss of that equil- ibrium so desirable to every economy. The tempera- ment of the individual should be Avell understood, and by diet, hygiene and medicaments a change is possible. But an acquaintance Avith physiology, is to kno\v the de- ficiencies of nature and the remedy. This may possibly seem an assertion in the abstract, but I insist that there is much in it Avhich the most su- perficial observer of medical science can see at the very first glance. All elementary, dietetic and hygienic means have a direct influence upon the development of the animal economy, its temperament and idiosyncrasis. Those nations that live in a southern climate must live according to the peculiarities of the climate, and their food, clothing, occupations and hygienic rules be subordinate to the physical influences surrounding them. Every means should be employed to increase the ozone. Nitrogenous food may be necessary for a certain infant, albuminous for another, and amylaceous and succulent for a third. And, if this is true, Ave should prescribe the same to the mother or select a nurse Avhose constitution Avould not favor the tendency or possess a predisposition to any abnormal idiosyn- crasies. With such a system Avonderful improvements may be brought about in the metamorphosis of life and groAvth. The change in the secretions, if not due to over-nu- trition, certainly suggest that either the quality of food or the atmosphere is possibly the cause. Excess in any one kind of alimentation, or Avhen too constantly used, is sure to become hurtful, solely be- 220 PROGRESSIVE MEDICINE. cause other elements are necessary to supply the various demands of the economy. If an excess of albuminous food should be used an excess of lymph Avould be the result, provided that albuminous nutrient Avas properly assimilated. The excess of nitrogenous food Avould create other disturbances and discrasia. The amyloid and succulent alone Avould likeAvise disturb the system, if used in great quantity, producing fats, heat, fermentations and mal-assimilation at the expense of blood and tissue. Childhood, therefore, can be nourished into groAvth and strength, even if it should inherit certain deficien- cies in its OAvn organizing force; and to these Ave must supply a patient and untiring care from their very birth up to tAvelve and fourteen years of age, when Avith the approximation to adult life, a neAV A'igor, as it were, bursts forth, disengaging the system from all the weaknesses of the past. And, furthermore, Ave must use a progressive treatment as the child groAvs by giv- ing him more exposure,more amusements, more motion, air, light and electricity. With these and the above suggestions, I dare say, one half of the strumous, phthisical, dyspeptics, and those of an anaemic condition could be permanently rescued from a life of discomfort and an early grave. Sanitary science, at the present day, should be the acme of all the medical schools, as preA'ention of disease. This is as necessary, if not more so, than medical treatment, after a disease is contracted. Bathing is eminently a great source of health. Na- tional baths should be established in every citv. They prevent morbific influences from invading and implant- ing malarious germs in the system, and diminish and equalize the temperature of the body; at the same time they stimulate excretion, and capillary activ- ity being kept up they assist the system in the process of ejection of the excrementa. DISEASES OF CHILDHOOD. 221 In hot summer days when the thermometer ranges from 80 to 90 and 100 and the number of the deaths of infant increases to a fearful mortality, the principle of bathing them morning and night Avould diminish that irritability produced by the excessive heat, and promote the secretions and excretions, controlling therefore all that hyperaemia and hyperaesthesia Avhich children are constantly suffering and giving alarming evidences of danger, and I feel at liberty to say, that these natural means Avould prevent many summer disorders by preserving the the equilibrium of the vital forces and organic functions. I do not intend to say that such a system of treat- ment Avould prevent all diseases of children, but I mean to say, that the excessive mortality Avould be greatly diminished; and I also Avould add, that medicaments are often required and have a beneficial effect in re-es- tablishing the equilibrium in chemico physiological dis- eases of the alimentary canal. Medicines Avill stimulate a torpid liver, a sluggish stomach; Avill pacify an irrit- able nervousness, change excessive and acrid secretions and stimulate gastric secretion. These agents are— Bryonia alb., Ipecac, Rheum, Cinchona, Acid hydro- chloric et phosph, Aloes calcarea phosph., et carbon, Natrum phosph. and Bismuth. If the circulation is giving symptoms of pyrexia: Belladonna, Digitalis, Aconite, Stibium and Hyoscianmus. If the nervous sys- tem is principally affected: Secalae corn., Cuprum, Pul- satilla, Veratrum alb., Helleborus, ingn., Kali Bromidi, Opium, Stramonia and Musk. In follicular disease of the stomach and boAvels, di- gestion and assimilation are comparatively abnormal; the peptones are defective and the gastric juice in- sufficient; then, Chlorine, Hydrochloric acid, Natrum, Iris Florentinae are indicated; starch is almost insolu-. ble by the weak salivary juice of children, and is not turned into sugar; lactic and butyric acids are 222 PROGRESSIVE MEDICINE. formed from animal food in adults. Natrum phosphor., calc phosph., kali carbon, etc., are all agents that Avill add the elements wanted in the salivary and gastric juice. The salivary juice aids the stomach in digestion in the transmission of starch into sugar, and sugar into lac- tic acid. The acids Avhich proceed from fatty globules (butyric) must be acted upon by the alkalinity of the saliva. And there is as it Avere, a double digestion go- ing on in the stomach, partly salivary and partly gastric, " and this is doubtless one of the causes of those differ- ences Avhich have been noticed betAveen natural and artificial digestion"—Draper. Amylaceous food is acted upon only by the strong saliva of the adult, there- fore farinaceous substances containing starch are indi- gestible to an infant. If encephaloid metastasis should take place, which often happens from dental or enteric irritation, use belladonna, stramonia, kali bromidi, helleborus, puis., etc.; but if the secretions are abnormal and acrid, with plephora, I find that, mere. sol. or alkalizatum Avill do well, and also ipecac and care carb. or carb. veg. In hepatic metastasis, hot fomentation to the liver and in- testinal canal, Avith belladonna, podophylum, aloes and nitric or hydrochloric acids And I find also camphora, natrum phosphor., cinchona and quinia to be very bene- ficial—(vide Burt's on Quinia). In the renal complications Avarm baths with terben- thenae, belladon, cantharidies, digitalis, cannabis sativa are excellent. In general hyperaesthesia chamomilla, coffea, ignatia, Pulsatilla, moscus, gelseminum, kali brom. should be used. The lymphatics and sympathetic systems are fre- quently directly or indirectly involved, and in such cases Avould suggest assafetida, belladonna, conium, au- rum, arsenicum alkalizatum, barita, iris florentina, san- DISEASES OF CHILDHOOD. 223 guinaria, hyosc, spongia, liepar sulphur, Scutellaria kali iodidi. The stomach is histogenetic in its functions, chiefly transforming nitrogenous food into blood; Avhile the office of the enteric digestion is to transmute the album- inoids into tissue, the amylaceous, glucose and fats, into respiratory food, or chalorificients. Here, we enter upon the chyle formation and pan- creatic functions; these special functions are too well known to require description. The amylaceous glucose and albuminous substances are variously acted upon by the intestinal juices and changed into lymph and tissue; others into fatty emulsion and chalorificients. The excrement system is thus seriously engaged, while the secernent is equally so (lacteals and villi) in changing the lymph into liquor sanguini. From this Ave can determine or rather Ave should be able to, Avhether Ave have gastric disorder or enteric, or both. Enteric digestion is subordinate to the gastric in a great degree; imperfect chyme cannot be acceptable to enteric digestion, hence imperfect chylification must take place. Gastro-enteric diseases, I venture to say, should be treated on a cliemico-physiological principle, adopting, hoAvever, other means in addition to the med- ical agents for the full accomplishment of a logical and successful treatment, and therefore Ave must add—air. light, heat, bathing, etc. These elements are indispen- sable to a perfect physical organizing principle. From Avhat has been said it is obvious that every physician has to make special examination of the di- gestive organs, their functions and their peculiarity. It is not sufficient to knoAv only that a child has diarrhea or constipation, irritibility, fever and Avant of appetite, but it is of great importance to knoAv Avhere the real morbid cause lies. If the fault lies in an in- sufficiency of digestion or elements of digestion, then 224 PROGRESSIVE MEDICINE. Avhat are they ? And it is in these very cases that the chemico-physiological treatment serves us so Avell. There are sporadic and symptomatic diseases of the digestive organs and in such cases AAre have to adopt first, those remedies thatAvill doaAvay Avith the primary cause, and second, give such remedies as will re-es- tablish the elements Avhich the materie morbi have either destroyed or changed. The Tissue-Remedies of Doctor Schtissler are doubt- less chemico-physiological agents, and all the principal and indispensable elements in the formation of the plasma. When Ave find the evacuations abnormally fetid Ave have formations of sulphurated hydrogen gas from animal decomposition, the urine is generally scanty and strongly tainted Avith ammonia and urea. But if Ave find odorless faeces, accompanied Avith much gas and pain there is undoubtedly carbonic, butyric or lactic gaseous fermentation, proceeding from a vegetable principle—fats, starch or succulent matters, Avhich not having been digested become fermented, acidulous and deleterious to the animal economy; and Avith it Ave fre- quently find a suppression of bile and an increase of Avhite odorless urine. In the first instance Ave find the greatest benefit from a change of food Avith sodium phosph., Hydrochloric acid, bismuth, sodium chloricum, natrum carbonic, etc. In the second instance, carbo-veg. alcohol, animal diet, hydrochloric acid, kali carbon, magnesia phosphorica, rhei-mercurius sol, hot water, etc Also aloes and colo- cynth. If exhaustion supervenes, and collapse is threatening it is Avell to prescribe burnt brandy, camphora, bella- donna, quinia, cinchona and chloride of ammonia, capsi- cum, arsenic, phosphorus, sponging, opium, etc. DISEASES OF CHILDHOOD. 225 CHAPTER VI. DISEASES OF CHILDHOOD.—Concluded. atrophia lymphatica.—Tabes—Entero—Mensenterica. This is a common disease in children, particularly so in those of a scrofulous diathesis; although at times it may be the result of other influences like malarious poisons, scarlet fever, measles, poor nutrition and on the contrary over-nutrition and neglect of hygiene. There are several nosological classifications of this diease, according to its locality and the organs it in- volves, viz., Tabes—Entero—Mesenterica, Tabes Pul- monalis, Tabes dorsalis, andgenerically called marasmus, including Tuberculosis and lymphatic tumors. It is the same disease only pervading different parts of the body, but pathologically and pathognomically the same. These classifications are very suggestive to the phy- sician. The disease generally and necessarily develops in those organs that are in greater use and greatly sup- plied by the lymphatic vessels and glands. It is obvious that childhood favors entero-mesenteric disorders considering that the alimentary canal is the focus of the A-egetative process, being constantly sub- ject to turgescence lympho-sanguina and hyperaesthesia, all centrally located in that fountain of alimentary activity, and hence its proneness to sporadic hyperaemia or symptomatic; to plethora, lymphatic engorgement, mal-assimilaiion and nutrition, asthenia, adynaemia and marasmus. 226 PROGRESSIVE MEDICINE. These various shades of the disease may become dan- gerous or even fatal, but more frequently it proves a propagator of lymphatic disorders over the Avhole system. It seminates the nucleos of constitutional dis- crasiae. From such atrophy and hypertrophy we have a sequel of pathological lesions too numerous to mention. It is enough to MIoav the disease in its in- cipient stage to see Avhat a myriad of complications it is capable of producing. My object is only to present clinical cases as evidences of my assertions. clinical case i. Delano Ames, three years old, of a lymphatico-nervo temperament; his father is very small in stature and anaemic, having all the marks of that peculiar dia- thesis. Physical Examination.—I found him generally ema- ciated, with small bones, narroAv chest, large head, enlargement of the abdomen, prominent red lips, Avhite skin, Avith fine light hair, large blue eyes, large mouth, and Avith the venous circulation very visible. Semiology.—Pulse 130 per minute; general and con- tinuous hyperaemia, Avith an afternoon pyrexia. Tem- perature 100. He Avas continually asking for Avater or meat; very irritable and restless; pale exhausted coun- tenence, Avith flushed cheeks in the afternoon; anaemic; had lost the poAver of locomotion. There Avas no pain in pressing upon the abdomen, no glandular enlarge- ment perceptible. He suffered with partial insomnia. As soon as he aAvoke he asked for meat and refused everything else. He had frequent evacuations of the boAvels of a greenish yelloAv color, mixed Avith mucous and faecal matter. The evacuations often changed the color to a broAvn and Avhitish clay, spongy, Avith an unpleasant odor; I took note of the fact that he Avas ravenous for meat. DISEASES OF CHILDHOOD. 227 The child had been sick for several months before he was brought to me, and his physician had diagnosed the case as one of helminthiasis. Of course the treat- ment proved not only a failure but redounded against the child's chances of recovery. Surely helminthiasis has a good many symptoms in common Avith many other enteric diseases, but the sal- ient points, and pathognomonic symptoms of this pecu- liar disease Avere certainly Avanting. There was no dilatation of the pupil, no itching at the anus, no grind- ing of the teeth; he did not wake up Avith a start, ap- pearing to be frightened by something; not the peculiar breath or stools; no Avhiteness around the mouth, no swalloAving in his sleep, no choking sensations Avere visi- ble. The absence of these symptoms indicated any- thing but helminthiasis. Etiology.—The symptoms and pathological condition of the child did not arise from sporadic cause, but cer- tainly from a Avell seated constitutional disease. In my examination of the case I could not find that the trouble could have been produced by either Avant of proper diet or hygiene, as the mother was an intelligent, careful and wealthy AAToman. The teething Avas out of question, and I could not trace anything to malarious poisons or to meteorolog- ical influences. The true and only visible cause was an inherited scrofulous diathesis, Avhich Avas running into a chronic discrasia. The mother was strongly built, but deaf, and of an unusual large bony frame. She had black eyes, large mouth, and a large intelligent head. She Avas inclined to plethora sanguina with a deep red corpuscular and fibrinated blood. She was very lively and good-natured. There Avas, if anything, a good abundance of lymph Avith a strong, healthy consti- tution to change it into blood and tissue. The father was feeble, and suffered with a chronic af- 228 PROGRESSIVE MEDICINE. fection of the laryngo-tracheal track, and looked as though laryngo-tracheal phthisis would sooner or later be the result. He was predisposed to consumption, and leucothe- mia; Avhereas his Avife Avas of a sanguine-lymphatic tem- perament," with plenty of vital and physical force. His frame and muscular development Avas defective, and emaciation had shoAvn an evident want of nutrition. The child inherited his father's idiosyncrasis. The objective symptoms of marasmus Avere evident in his physical development; the subjecth'e Avere prom- inently observable in the paroxysms of hyper-exiae, in the abnormal faecal evacuations, in the SAvollen abdomen thirst, hunger, emaciation, adynaemia, exhaustion, tem- perature of the body, mal-assimilation and nutrition. It was also evident that a normal metamorphosis of chyle was not going on; the proteine compound Avas de- fective, hence crude lymph and poor blood, and there- fore the plastic force was insufficient. The enteric and lymphatic vessels Avere secreting Aveak and abnormal juices (Humorum-acremonia). The lacteals and villi had the absorption and transmu- tation of these juices, and turned them into blood in an imperfect condition; hence discrasia. Adynaemia and asthenia Avere natural consequences from the general Avant of proper assimilation of the nutrients. The lym- phatics, Avere atrophic, Aveak and incapable of perform- ing their normal functions, and thus the Avhole process of organization Avas interfered Avith. Such being the condition of the patient I looked dis- mayed at the negligence Avith Avhich the child had been treated. The disease had already Aveakened the pa- tient greatly, -and I undertook the care of it Avith full appreciation of the difficulties and dangers attending it. It Avas an imperative duty to select a nutriment that would be easily assimilated by the impaired and turges- DISEASES OF CHILDHOOD. 229 cent organs—Avithout wrhich no favorable progress could be expected. The medical treatment Avas likewise of great impor- tance, so as to calm Avithout irritating, change Avithout causing dangerous metastic complications,and results elseAvhere. Medical Treatment.—The splanchic and the sympa- thetic nerves were in a state of complete exhaustion. The absorbing and secreting organs Avere deficient of nervous force. Orgasmus Avas substituted by asthenia and enfeebled circulation ; then again, by subsequent paroxysm of pyrexia. .Now this state of transitory phenomena Avere gradu- ally destroying the vital force, organic function, and physical equilibrium. It Avas necessary that Ave should employ medicaments Avhich could have if possible, a specific effect upon the vaso-motory system and thus allaying irritability, turgescence and pyrexia. I prescribed the following remedies: R. Atropa belladonna, 1-dec. grs. xxiv. M. chart., xxiv. R. Barita mur., 3-dec. grs. xxiv. M. chart., xxiv. Dose—One poAvder'every hour alternately. I saAv him next day and found that he slept better, had less irritability and better pulse. Yet the secre- tions Avere very unnatural and I believed a change or stimulous upon organic action was necessary. R. Natrum phosph., 3-dec grs. xxx. M. chart., xv. R. Belladonna, 3-dec. gutt. xii. Aqua fort., ? ii. To be taken alternately every tAvo hours. On the fourth day I saAv an improvement in the secre- tions and digestion. The faecal matter Avas more yelloAv and natural—no 230 PROGRESSIVE MEDICINE. offensive odor, and less frequent. He was quieter, and the thirst and pyrexia had abated. At the same time I forbade meat entirely, and put him on cream, oyster broth, clam soup, beef broth with rice, bread without butter. On the seventh day he Avas still progressing although he had had a relapse for twenty hours. I had him sponged in salt and Avater tAvice a day. Cold Avater in the morning, tepid water at night. The belladonna had done Avell, and it Avas losing its effect perceptibly, so I gave him,— R. Pulsatilla, 3-dec. gutt. xii. Aqua distill., f ii. R. Merc sol., 3-dec. gutt. xxii. M. chart., xii. Dose—One poAvder to every two doses of the pulsatilla. In another word I gave him two doses of pulsatilla to one of Mercurius. He took the above for four days, and the progress was continuous. No more thirst, seldom any noticeable change of temperature, appetite more natural, stools only about four in tAventy-four hours, more natural also. The eleventh day of treatment I ordered for diet, oat- meal boiled Avith cream and thoroughly gelatinized— no grains to remain undissolved, rice Avith cream, and beef-tea or juice, with bread, cocoa and milk in the morning. On the twelfth day I prescribed R. Bismuth subnitr., 3-dec. grs. xxx. M. chart., xv. R. Calc sphosph., 3-dec. grs. xxx. M. chart., xv. Dose—one poAvder every tAvo hours alternately. He was kept on these poAvders for three days. I alloAved him three days Avithout medicines, so as to exhaust the action of those taken. I saw him again on the eighteenth day. He kept his DISEASES OF CHILDHOOD. 231 own, but it was evident that more medical treatment was required. I prescribed R. Liquor Potass-arsen., 3-dec gutt. xii. Aqua distill., | ii. R. Capsicum, 5-dec gutt. xii. Aqua, f ii. Under these medicaments he improved greatly. The debility left him, he commenced to Avalk and play, slept well and ate regularly. On the tAventy-fourth day I changed his medicine for R. Ferrum peroxyd, 3-dec grs. lx. M. chart., xxx. R. Barita mur., 3-dec. grs. xxx. M. chart., xx. Dose—One powder every two hours, alternately. It is to be observed that aconite Avas not used because there Avas no inflammatory condition. There Avas a passive hyperaemia but the tendency was to adynaemia and asthenia. He took the above remedies for two weefcs and by that time he was playing in the open air. I gave him R. Aurum, 6-dec grs. lx. M. et devide chart, xxx. R. Magnesia phosph., 3-dec. grs. lx. M. chart, xxx. Dose—One powder every tAvo hours alternately. He took this medicine for eight days. I consider this not anti-scrofulous treatment but chemico-physiological, Avhich expresses better our meaning. Finally I gave R. Kali'chloras, 3-dec. grs. lx. M. chart., xxxx. R. Ferrum peroxyd, 3-dec. grs. lx. M. chart., xl. Dose—One poAvder every three hours during the day. The dietetic and hygenic treatment remained the 232 PROGRESSIVE MEDICINE. same. Treatment was kept up for six months, and the result was a cure. clinical case ii. George Henderson, eleven years of age, of a nervo- lymphatic temperament. He Avas brought up in a healthy country place. His mother and father Avere healthy. He had tAvo sisters and both Avere healthy. His diet was Avhat is called country food: good deal of ham and pork, fried meats and heavy unseasoned vegetables, like potatoes, squash, those abominations called pies, preserves, molasses, hot cakes, bread and teas. The buck-wheat cakes and the griddle and pan cakes Avere abounding on their table Avith sour cheese and cabbage, etc. The bill of fare Avas surely an anti-dietetic one par excellence, and particularly to a delicate child. Physical Examination.—Large head, narroAv chest small stature for his age, Avhite skin, blue veins, large mouth, large pupil. Heart's action irregular and irrit- able, its rhythms being abnormal without any organic lesion, its walls thin and somewhat dilated (dilatation without hypertrophy). Respiration very irregular, pro- longed expiration Avith a quick short inspiration shoAV- ing a deficiency in the pulmonary expansion and a difficulty of contraction. The expiration was diaphrag- matic. There Avas a broncho-laryngeal cough Avith free expectoration and mucous rale; and on percussion and auscultation it was discovered that the bronchioles were getting filled with a muco-purulent secretion. The air cells could get but a small amount of air, and deoxida- tion Avas therefore imperfect; carbonization avus pros- trating the physical and vital forces to a great degree, hence fever, quick pulse, agitation, high temperature, insomnia, apepsia, hallucinations, etc. The abdomen Avas swollen and painful on pressure and adenoid prominences Avere clearly felt, upon a care- ful examination. The joints of the wrists, elboAvs DISEASES OF CHILDHOOD. 233 knees, and ankles Avere all SAvollen and painful. His legs Avere flexed upon the femor and could not be extended Avithout much pain, and even then the hot SAvelling of the knee (subacute inflammation) Avas threatening serious lesion of the synovial membranes. He had also tumefaction of the submaxillary glands and finally there Avas turgescence and ichorous condition of all the lymphatic system. Structurally I believe the Avhole lymphatic system Avas hetero-plastic lymphoma. From these outlines Ave can imagine the complications and threatening dangers to all the physical and organi- zing principles. It Avas a condition in Avhich life Avas fundamentally undermined. Semiology.—I found him restless, exhausted and sleep- less. Pulse 115—temperature 102£. Great thirst, constipation and Want of appetite and digestion. He passed a small quantity of urine of a high specific gravity; strongly acid. His tongue Avas coated yelloAv- ish Avhite of a slimy nature, and Avas tremulous and pale. He complained of pain in the joints and abdomen. Could not bear the bed clothes upon his stomach and abdomen, and he lay constantly on one side. His sleep Avas disturbed by visions, and gave signs of encheohaloid hyperaestesia caused by excitability. It Avas an aggravated case and complicated with vital de- rangements. The patient Avas emaciated to the last degree, and asthenia and adynaemia Avere evidently going on to a fatal issue. The proteine compound was evidently disarranged by heterogenous elements, and the histogenetic metamor- phosis Avas imperfect and insufficient. The blood and tissue making process became contaminated by physical mal-assimilation. The cervicle and mesenteric glands Avere similarly tumified and turgescent. The pancreas sympathized Avith the entero-mesenteric 234 PROGRESSIVE MEDICINE. trouble and their physical relations were similarly affected. The red corpuscles Avere feAv in number and the fibrin Avere lessened. The blood abounded in serum and Avhite corpuscles, with a Avant of the plastic materials like iron, phosphated lime, sodium, etc., and thus the mould was radically changed and the principle of a higher development (vital and physical groAvth) Avas partly vitiated. Etiology.—In examining these conditions of things, it was necessary to retrace our steps and examine the soil from Avhence such a deteriorated constitution arose. To a casual observer, I suppose, no one could see any indications of poor-health in the parents; they Avere Avell developed people, and apparently enjoyed good health, still, during the examination, I found that the mother had been a delicate girl; had suffered greatly with some glandular trouble, and her growth Avas sIoav and late. The other children, although well, had some peculiar features (idiosyncratic of a scrofulous constitu- tion). Red lips Avith an unnatural Avhite skin, long bones, large hands and feet. There Avas an anaemic condition of the blood, although there Avas not real ema- ciation. The mother Avas a tall Avoman, Avell developed and quite fleshy: yet, she Avas lazy, tired and ahvays com- plaining. There Avas a lack of physico-vital force. She Avas of a sandy color, hair fine and dry, light life- less blue eyes, large head, thin long neck and large hands and feet. There was nothing of that ruddy com- plexion so common among healthy country people. And indeed the necessity that compelled her to live in the primitive style, facing the storms of country ex- posure and Avork, the fresh air, activity, light, heat and electricity, supplied the deficiency of her constitu- tion, and brought about those metamorphoses Avhich were imperative to the progress of the great phenom- DISEASES OF CHILDHOOD. 235 ena of physical development, and Avithout Avhich, she Avould have died of pulmonary tuberculosis. The phen- omena of composition must be equilibrated by decom- position; and in reality, there can be no composition Avithout the proper amount of decomposition. The pro- cess of growth springs from the physical activity of de- composition, and from it new forces and neAV formations. Her marriage Avas also a neAV physical change, being followed by the act of procreation, thus forcing the organs into a physiological activity which demanded physical and vital organization and force. This brought about the elements of plastic force, and her whole physical process received that impetus, which either develops a static animal life, or else destroys the one that does not possess the spring of growth. The motion and hence decomposition kept up an organizing force due to her country life. The very germ of the mother Avas imperfect and lacking in those elements in- separable from a perfect physiological condition, and nothing, but the elementary principles of nature sup- plied the elements of organization and force, Avhich Avere wanting to a great degree, in the very pabul- um-vitae. Hetero-lymphoma, and atrophia lymphatica, arise from a defective proteine compound, hence proteinous disease. This is scrofula. This patient Avas a type of the mother and inherited her idiosyncrasis. The gener- ally faulty physical organization rendered the system incapable of assimilation and chylification, so that the process of repair was not equal to the necessities of growth and waste, hence emaciation and general ex- haustion. The causes from which this physical trouble arose, were unavoidable defects in the animal economy and composition. It was inherited and hence trans- planted from mother to son. Exciting Causes.--These were only additional evils, but mot' fundamental, and arose from the diet which was 236 PROGRESSIVE MEDICINE. quite irritating and indigestible, of namely, boiled po« tatoes, ham, fried meats, hot bread and pies, hot cakes, coffee, tea, and pastry generally. These things could not be assimilated and a formation of gastric crudities Avas unavoidable, and therefore the chyle Avas Aveak and impure. Medical agents employed alone in these cases -will have no result, as the question is more physiological than simply locally pathological. The cod-liver oil and iron of the old school indiscriminately prescribed by the so-called rational doctors (Allopaths) would always re- sult in sad failure unless accompanied by a systematic hygiene and dietetic treatment. Medical Treatment.—I considered the case a danger- ous one and treated him Avith much solicitude. R. Belladonna, 3-dec. gutt. xii. Aqua distill., f ii. R. Mercurius Proto-iodid., 3-dec. grs. xxiv. M. chart., xii. Dose—one teaspoonful every hour, alternately with one powder and a Avarm bath every night. I kept the patient on these remedies for three days with a light animal diet composed of broth and cream. I found no improA'ement, but rather some discourag- ing symptoms of hallucination insomnia, much pain and SAvelling in the abdomen, Avithout appetite. I acknoAvledge that I Avas disappointed, yet I kneAv that a crisis must be the result of this profound phys- ical malady. BoAvels constipated, high fever and still painful joints. He shoAved considerable bronchial irrit- ation Avith a general irritability of the symoathetic system and abdomen. On the fourth day I gaA^e nim R. Atropa belladonna, 6-dec gutt. xii. Aqua distill., f ii. R. Emplastrum Conii upon the abdomen with DISEASES OF CHILDHOOD. 237 R. Aurum muriat., 3-dec. grs. xxiv. M. chart, xii. Dose—one poAvder every hour alternately with a tea- spoonful of the liquid. On the fifth day I found him more comfortable. He had had a better night, less fever, no hallucinations, free discharge of urine and boAvels; abdomen less pain- ful and less sAvollen. On the sixth and seventh days the temperature Avas 99; pulse 100. He had thirst, and the secretions Avere better. He perspired freely and was comparatively comfortable. The hemlock poultice Avas reneAved twice a day and gave great relief. He received the same treatment till he reached the tenth day and then he had an exacerbation, temporary, and Avithout any ap- parent cause. I changed the remedies: R. Hysciamus 1-dec gutt. xii. Aqua distill., f ii. R. Kali iodidi, 3-dec. grs. xxiv. M. chart., xii. Dose—one teaspoonful every hour alternately with a powder. On my return I found him better, the fever having left him, the boAvels moved and the glandular tumefac- tion Avas diminishing. I kept him on this treatment for several days, and on the fifteenth day I gave him R. Podophyl, 3-dec grs. xxx. M. chart., xv. R. Aurum mur., 3-dec. grs. xxx, M. chart., xv. It suggested to me, the fever having left, and the irritability of the brain being overcome, that I had to look after the secretions, and in podophylum Avith au- rum, I had tAvo great remedies for both the absorbents and the secretions. In tAvo or three days I had the pleasure to see that 238 PROGRESSIVE MEDICINE. the faeces Avere more natural and the urine less acid and less ammoniacal; the ichorous secretions were carried aAvay and were changed. The digestion having improved, the diet given was more generous and solid, viz., roast beef, beef steak, mutton, eggs, Avine and cream, bread and cocoa, etc. I continued for some Aveeks with aurum, belladonna and aurum, changing the medicines every Aveek. On the fifth Aveek I found nearly all the sAvelling of the joints gone down, the abdomen retracted, and almost natural, the daily faecal discharges were regular and natural, and so I had him brought out in the open air on a mattress, put in a Avagon and thus I kept him go- ing out every day during pleasant Aveather. His improvement was noAV rapid; his appetite raven- ous and his general physical condition gaining rapidly. I gave him during the sixth and seventh Aveek R. Calc phosphoric, 3-dec. gr. 1. M. chart., xxx. R. Ferrum peroxyd., 3-dec. grs. 1. M. chart, xxx. Dose—one poAvder every three hours, alternately. On the eighth Aveek I left him apparently Avell and I only recommended generous diet, fresh air, exercise and salt Avater baths Avith occasionally iodized cod liver oil. Here Ave havTe a real homoeopathic treatment and cure, because, Avere Ave to give such remedies to a Avell per- son (in a larger quantity) Ave Avould surely produce ir- ritabilities of the gastro-enteric canal Avith pyrexiae, irritability and general physical derangement. The plastic force Avould deteriorate through an histogenetie interference. I also predicted a return of the same trouble (less in intensity) as soon as the AAdnter season would compel the boy to be closed in the house. The prediction Avas fully A'erified. He had a return of the cough, the fever and the SAvelling; but Avith the same treatment in tAvo Aveeks he was Avell again. DISEASES OF CHILDHOOD. 239 I gave him several other remedies, as magnesia phosph., barita carbon, natrum phosph., ferrum, etc. CLINICAL CASE III. John Bartlett, fifteen months old. His mother died soon after his birth and he was brought up by the bot- tle. The surrounding incidents Avere unfavorable, the mother being sickly during pregnancy and died of puer- peral fever soon after his birth. Physical Examination.—I found the child in the ex- treme condition of emaciation. His lungs Avere sound; the heart Avas normal organically and functionally. Stomach and boAvels retracted Avithout heat. His phy- cal development demonstrated general atrophy. He had a large head, blue eyes, light hair and Avhite skin, with a prominent venous circulation. Pulse 140; temperature 100. His bones were very small, and in truth, he had not groAvn since he was three months old. Asthenia and aolynaemia Avith turgescense of the lymphatic vessels and glands Avere decided evi- dences of the disease, in consequence of Avhich great hvpereasthesia existed. Perfect anaetnia and enerva- tion threatened the very foundation of his life. I Avas called to consult Avith another physician Avho, after six Aveeks of treatment, acknoAvledged that he knew nothing of the disease. He treated the case for cholera infantum, under the impression that the fre- quent intestinal evacuations were sure indications of that disease. Semiology.—When I visited the child I found him lying in his crib, looking almost like a skeleton, and more of a corpse than a living being. Great exhaustion had set in, Avhich was evinced by his very posture. His moans and feeble cries indicated great physical enervation. His legs Avere abducted, his arms throAvn off his body, eyes shut, quick respiration, and too feeble to change his position. The skin alone covered the 240 PROGRESSIVE MEDICINE. bony structure—no fat or muscles could be seen. He constantly called for nutrition (the bottle) and the more of the milk he drank the more he Avanted. His boAvels moved almost as frequently as he took nutriment. The unquenchable thirst caused by the hyperaemic condi- tion of the digestive organs demanded a continuous supply of fluids. As soon as he had received the milk, he passed it off through the boAvels in a sour and curdled condition. The fermenting of the milk in the stomach produced carbonic acid, in consequence of Avhich the child suf- fered Avith flatulant colic. He Avould take nothing but milk, day and night, and its undigested condition produced symptoms of chol- erine, but there Avere not the usual severe symptoms of gastro-enteretis of the cholera infantum. On examination of the abdomen I found that it had no glandular SAvelling, no pain, and no heat; on the con- trary, there was an evident condition of atrophy, in the excernent system. The teeth Avere not visible; and the gums giving no signs of irritation. I found that the milk Avas good, and the child was also Avell attended; the atmosphere Avas hot, but there Avere no extreme meteorological diurnal or nightly changes; the Aveather Avas of course a source of exhaustive influence, but the true cause lay deep in the physical economy. Etiology.—Taking a coup aVceil of the physical condi- tion of the child, the objective appearances were only confirmed by the subjective symptoms—marasmus or entero-mesenteric atrophia. The mother Avas feeble at the time of conception, be- ing herself of a scrofulous diathesis; the act of procrea- tion did not improve the physical conditions Avith her, as it did Avith our country matron Avhom Ave have studied in a previous case. The country matron Avorked hard and had the beneficial influence of perfect physical DISEASES OF CHILDHOOD. 241 metamorphosis and reorganization, while this young wife was indulged, and lived in the depressing atmos- pherical influence of a southern climate and a retired life. The hyperaemia-lymphatica Avas inherited from birth, and therefore the proteine compound Avas actually in a state of retrogression, and the mal-assimilated chyle, prevented a normal process of histogenesis. The fault Avas fundamental and physico-vital. Medical Treatment.—Doubtless milk Avas not the food for that feeble baby. The caseine, sugar, butter, and albumen were ingredients Avhich the lymphatics would not thoroughly annualize, and indeed, before these nutrients reached the lymphatics, they were converted into imperfect chyle. That emaciated child required animalized food (nitro- genous) Avith the triplo-phosphates to give plasticity to the blood. 1. It was a case of insufficiency in the elements of nutrition—milk ; 2, the physical compound (proteos) Avas deficient; and 3, physically unable to organize out of a Avatery fluid a sufficient quantity of the elements of nutrition and groAvth—(Histogeneses) hence the disease in question. It Avas suggested that the bottle be given up, naturally enough this Avas acceded to Avith great reluctance on the part of the attendants, but it Avas an imperative necessity. R. Belladonna, 3-dec gutt. xii. Aqua distill., f ii. R. Cainphora, 3-dec. gutt. xxiv. Aqua distill., f ii. Dose—one teaspoonful of the liquid alternately every hour and a Avarm bath Avith salt in it. Diet.—Beef tea, almost like blood; one teaspoonful every tAAro hours. Burnt brandy Avith Avater; one tea- spoonful every hour; rice Avater for a drink—at first he refused it and cried for a long time; then he slept and 242 PROGRESSIVE MEDICINE. woke up refreshed. The beef tea Avas given Avithout any trouble. The brandy he liked. I called tAventy-four hours after, and I found by a se- rious struggle Ave had succeeded in making him take the food. His pulse Avas better; he slept two hours; his evacuations Avere less frequent. On the third day I found the pulse fuller in volume, less in frequency; the temperature Avas loAver, the thirst had diminished and he did not ask for the bottle. Evacuations yelloAv, more solid, the carbonic gas inflat- ing the intestinal canal, and decidedly diminished; and the child rested day and night. It Avas advisable to change the medicament because it Avas not covering all the physical troubles, his evacua- tions being still too frequent Avith considerable fretting. R, Plumb, acetatum, 3-dec grs. xx. M. chart., xv. R. Quin. sulph., 3-dec. grs. xx. M. chart., xv. Dose—one powder every hour, alternately, till six at night, then R. Lactucasia, 1-dec gutt. xxiv. Aqua fortis, f ii. Dose—one teaspoonful every hour during insomnia at night. Sixth day: The grandmother Avas very much encour- aged as the treatment seemed so successful; Avith a few little returns of excessive Avatery evacuations, the case progressed favorably. I found my patient looking better, taking notice of his grandmother and hating the doctor as usual. The evacuations were only about eight in tAventy-four hours; the urine was deeper in color and less in quantity. The food became rather tiresome to the child, so I ordered rice boiled in broth, and clam broth. As the child needed great invigoration I gave him phosphorus in glycerine—one teaspoonful every tAvo hours. DISEASES OF CHILDHOOD. 243 R. Phosphorus, 6-dec gutt. xx. Glycerine (pure), f iii. ' R. Calc phosph., 3-dec. grs. xii. M. chart., xii. He took the medicines for two days Avith great bene- fit, but the evacuations became too frequent, so I had to keep them under restraint. On the eighth day I prescribed the phosphorus Avith a change in the place of the calcarea, viz.: R. Rheum et natrum 3-dec, grs. xxiv. M. chart., xii. To be taken alternately Avith the phosphorus every tAvo hours. The diet Avas also changed. I gave bread and broth boiled together for an hour, and then strained. I sub- stituted milk punch for the brandy omitting the sugar. The tenth, eleventh and twelfth days the case con- tinued to improAre and the nature of the secretions Ave re much better under the effect of the Rheum et natrum. Thirteenth day: I found him rather cheerful, and some indication of teething. Before, he Avas physically unable to form sufficient phosphate of lime to produce bone and teeth; and this sign Avas indeed an evidence of the good result of chemico-physiological principles which I adopted in the treatment. The progress of the case Avent on Avith very feAv in- terruptions, and the boAvels and the chylopositic viscera became thoroughly disengaged from those elements of disintegration Avhich Avere reducing the economy to a state of dissolution. The dietetic treatment Avas someAvhat A'aried. I gaATe him rice cooked in condensed milk, Avith salt and tAvo grains of calcarea phosphorica in it. He digested light cocoa, mutton broth and bread, sago, and a composition of peas, beans and lentils, strained in the broth, or even milk. The above three vegetables are Avhat is called nitrogenous vegetables or leguminous food. 244 . PROGRESSIVE MEDICINE. I proceeded by giving R. Magnesia phosph., 6-dec gr. xxx. Dose—one poAvder every three hours. And ended Avith Barita carb., Ferrum peroxid, Aurum muriat. Calcarea carbonica, quinia sulph., kali arsenic, kali sulph., kali chloras; fresh air, bathing morning and night; cold Avater in the morning, Avarm at night. In six Aveeks the child Avas cured. CLINICAL CASE IV. A female child, about eighteen months old, of nervo- lymphatic temperament. She Avas almost in articulo- mortis. She had been sick for four months and treated by Allopathic physicians in good standing. She AA'as well dosed and, most emphatically, empirically treated, i. e., Dover's poAvders to make her sleep and check the excessive evacuations, bismuth and pepsine, and gray' poAvder, to use their Avord, as alteratives; ipecac and rheum in large doses, chalk mixture, and astringents, and thus it Avent on to a chronic stage. The child Avas treated for cholera infantum, and then for marasmus; they had her at the sea shore and although she improved someAvhat, the irrational treatment could not aid the vis-medicatricae naturae in its efforts against the disorder. Physical Examination.—Lungs sound, heart's action very irritable and feeble, pulse thread like and very frequent (140), temperature low, breath offensive, and tongue reddish on the edges, Avhite in the middle. No glandular enlargement Avas perceptible to the touch, heat, turgescence undoubtedly existed. Abdomen SAvollen, and full of gas, painful on touch and hot, eyes sunken, features shriveled and emaciated. The liver Avas enlarged and slightly jminful. The general ap- pearance Avas, that of extreme exhaustion and.anaemia. Semiology.—The child Avas in her mother's arms where she Avas accustomed to be carried around the DISEASES OF CHILDHOOD. 245 room for hours, and thus she Avas kept comparatively quiet, but the moment the motion ceased the child Avould scream until the Avalking Avas resumed; she Avas moaning, but evidently not asleep. Every attendant Avas tired out, for they Avere on the go, day and night. The pulse indicated adynaemia, agitation, hyperaesthesia, in the highest degree, with asthenia following. She was ravenous for the bottle, and what is more, had it to her heart's content. I Avas soon satisfied that I had a case of entero-mes- enteritis cronica Avith hetero-plastic lymphoma. She inherited a scrofulous diathesis from the father and mother; both parents Avere delicate, nervous and feeble. She had a passage every fifteen minutes, Avhich Avas Avatery and of a chalk color Avith curdled milk, some- times greenish and sometimes mucous, but there Avas no biliary fluid in the evacuations. She had been over- fed and kept on feathers in close rooms. All the enteric juices Avere ichorous, perverted and irritating. The physico-vital forces.Avere in the most critical condition. Etiology.—In examining the proximate and remote causes I found that the father Avas so nervous that his speech Avas often affected, his eyes shoAved a Aveakness (or a specie of scrofulous ophthalmia). His digestive or- gans Avere Aveak and suffered Avith dyspepsia. He had small blue eyes, light hair and a large head. The mother Avas a brunette, Avith piercing black eyes, Avhite skin, black hair and large mouth. She Avas very careless of her diet and A'ery imprudent as to exposure. She Avas of delicate health and scrofulous; she had lost tAvo brothers, one Avith hepatitis, another Avith consump- tion. The remote predisposing causes Avere inherited scrofula and a ner\Tous idiosyncrasis. The proximate and exciting causes Avere over-nutrition, Avant of air and light, etc. (Induced causes). The pathognomonic symptoms of struma from entero- mesenteritis Avere strongly marked. I could not find 246 PROGRESSIVE MEDICINE. that the child's disorder had commenced Avith any plethora or enteritis; in that case her condition Avould have been the natural sequence of inflammatory dis ease of the intestines. If there had been any ple- thora in the first stage, it was undoubtedly lymphatic Avith turgescence and tumefaction. When an inflammatory condition is first developed, if death does not take place, it is folloAved by asthenia, adynaemia and atrophy-lymphatica to a greater or less extent, and disorganization is the unavoidable result Avhen such a morbid process is prolonged. The secondary lesions of distant parts or organs, are the results of reflex metastasis, viz., the ameloid dis- order, hepatic suppression, renal complications, serous secretions or pulmonic irritability, hyperaemia, and tuberculosis. The idiopathic causes are sudden meteorological changes, malarial poisons, insufficient nutrition, abnor- mal milk, Avant of the proper diurnal ablutions and cleanliness, and teething. Hygiene and Dietetics.— HaA'ing noticed the great anxiety of the parents, and their lack of judgment and proper conception of Avhat Avas required by the sick child, and their total Avant of instructions by their for- mer physicians, I immediately informed them of their duties and desired adherence to my directions. This mode of procedure Avas neAV to them and decidedly difficult to carry out. 1. The child should be put in her crib, on a hard mat- tress, so as to remain in an incumbent and comfortable position. 2. The room should be Avell ventilated, and Avhen the child Avas aAvake to let in all the light possible. 3. A Avarm bath at night and a cold one in the morning. 4. Not to move the child from her bed, as motion, I considered, a disturbing element to the irritable intes- tines. Milk Avas at once set aside ; mutton broth and beef DISEASES OF CHILDHOOD. 247 teaAvere to take its place, and at intervals burnt brandy and sugar with water. Medical Treatment.—I ahvays consider belladonna as the great invigorator of the cardiac circulation and at the same time ameliorating ganglionic irritability, par- ticularly that of the splanchnic and vasa-motor nerve. R. Belladonna, 3-dec gutt. xxiv. Aqua distillata, f ii. R. Merc solubilis, 3-dec grs. xii. M. chart., xii. Dose—one teaspoonful every hour alternately with a poAvder. On the second day I found the child had rested bet- ter; the boAvels Avere more quiet, and contained more faecal matter; she passed more Avater, Avhich had more color. Her skin Avas Avarmer, pulse stronger and less agi- tated; her general countenance Avas better; still the dangerous symptoms were yet existing only in a less degree. I continued the treatment for tAventy-four hours longer. On the fourth day I found the patient very irritable and the evacuations as bad as ever. I suspected that they deviated^ from my instructions: they acknoAA'ledged to have given the child some milk and to nave taken her out of her crib. I Avas at last satisfied that my ad- vice Avas not ill-judged and that they had fully tasted the result of contrary doings. I, of course, repeated my advice only in stronger terms, and left. R. Lactucaria, 3-dec. gutt. xxiv. Aqua distill. R. Rhei et natr. 3-dec grs. xxiv. M. chart., xii. Dose—one teaspoonful of the liquid every hour, al- ternately Avith the poAvders. - Fifth day:—The patient Avas more comfortable. It 248 PROGRESSIVE MEDICINE. had passed a good night; the evacuations Avere only few in number, of better color and contained more faecal matter. The child Avas less ravenous and took what they gave her. The diet Avas continued and the medi- cal treatment also. Seventh day:—I found the child Avith a stronger pulse, a AA-arm body, and faecal evacuations. The pass- ages Avere less painful, but they had an offensive odor. I Avas prepared to find nitrogenous undigestible excre- tions, so I gave her R. Carbo-vegatabilis, 3-dec. grs. xxiv. M. chart., xii. R. Camphora, 3;dec gutt. xxiv. Aqua fort., f ii. These remedies Avere given on a therapeutical prin- ciple. The Avell-knoAvn effect of carbo-vegetabilis, so far as Ave knoAv, is antiseptic, and prevents decomposi- tion and fermentation. The camphora is an organizing element as its effects are curative in cases of svncope in Avant of organic function in defective circulation and hepatic torpidity. It also affects strongly the motor sensory system of nerves. Eighth day:—I found the secretions improved and the excretion not alarming; the child Avas iioav gaining strength and its digestive organs Avere quieted doAvn under proper therapeutical means. Her tongue Avas of a healthful red and the flatulency nearly gone. The odor of the faeces changed for the better and the vital- ity of the patient Avas considerably increased, yet in- somnia Avas still a great trouble. I prescribed for the ninth day R. Potass Bromidi, grs. xxx. Aqua distill., ? iv. Dose—one teaspoonful every hour at night until she fell asleep. R. Arsenic alkalizatum, 3-dec. gutt. xii.j Aqua, f ii. ISEASES OF CHILDHOOD. 249 Dose—One teaspoonful every tAvo hours during the day. Tenth day:—The child Avas still improving and laughed and played. Her evacuations Avere yellow, skin Avarm, appetite natural, slept Avell and cried but little; no fever and very little irritability. TAvelfth day :—Went on Avith the same medical treat- ment; but I changed the dietetic to condensed milk Avith brandy, beef broth Avith rice, and glycerine. Thirteenth day:—Child still improving. I pre- scribed. R. Calc phosph. 3-dec. grs. xl. M. chart., xx. R. Pulsatilla, 3-dec gutt. xxx. Aqua, f iii. Dose—one poAvder every hour alternately with the liquid. Fourteenth and Fifteenth days:—I continued the same treatment. I found that the child's whole organ- ism Avas in a state of change; noAV I considered that the day of the crisis had passed and that the climax having arrived the disease Avas entirely under submission. Sixteenth day:— R. Magnesia phosph., 3-dec. grs. xxiv. M. chart., xii. R. Belladonna, 3-dec gutt. xii. Aqua pura, f ii. Dose—one poAvder alternately Avith a teaspoonful of the liquid. The infant was still very much emaciated, and Avant- ing animal heat which I knew her imperfect poAver of organization could not yet supply. I ordered R. 01. Morrhua, ^ ii. One half teaspoonful to be given in brandy tAvice a day; and also R. Ferrum peroxydum, 3-dec. grs. xxiv. M. chart., xii. Dose—one poAvder every three hours. 250 PROGRESSIVE MEDICINE. I continued this treatment for one Aveek with percep- tible benefit. On the twenty-first day I gave her R. Liquor potass arsenic, 3-dec gutt. xxiv. Aqua distillata, ■z ii. And iodized cod liver oil (Fougera's). She improved under this treatment; slept well, cut tAvo teeth, became fat and strong and ate regularly. I alloAved cocoa in the morning Avith condensed milk meat at noon Avith rice and bread, yolk of an egg Avith Avater and brandy (without milk), beef broth and ver- micelli or bread. On the thirtieth day I ordered R. Ferrum peroxidum, 3-dec. grs. lx. M. chart., xl. R. Calc phosph., 3-dec grs. lx. M. chart., xl. Dose—one poAvder alternately every three nours, changing with cod-liver oil. The seventh Aveek she was entirely cured. Tavo important remedies which I used in these cases are, ipecac and plumbum aceticum: the first in great irritability, the second in great spas- modic pains. I also used oleum ricinis Avhen great irri- tation and bearing down existed. CLINICAL CASE V. APllTEOUS DISEASE—THRUSH. A baby of a few days old gave signs of pain in the stomach. He cried and refused to nurse. He Avas born under very unfavorable auspices. The mother Avhen pregnant lhred for several months before the birth of the child on bread and tea, and a feAv potatoes and pork. She Avas very poor and her husband made her poorer and miserable. She came to my house and there gave birth to this child. When born he Avas very small and emaciated; DISEASES OF CHILDHOOD. 251 the cord Avas very small and indicated anaemia. He Avas fully groAvn as far as the bony structure Avas concerned, but atrophy mesenterica Avas the prominent pathogno- monic feature. Physical Examination.—The lungs Avere sound with feeble respiration. The heart's rythins Avere irregular and feeble. Large bones, small head and feeble pulse. The navel retracted in a very short time after birth, defective venous circulation (cyanosis), tongue coated Avhite, Avhich in a short time developed in aptheous form (Thrush). The mouth Avas hot and dry. He Avas at times very pale, at others, flushed and cyanotic. Semiology.—Tavo or three days after birth the child refused to take the bottle. He cried a great deal and seemed to be in pain. I thought it Avas colic, from in- digestible milk, and ordered lycopodium and natrum carbonicum. On the fourth day the child Avas appar- ently improved and nursed better. When I saAv him tAvo days after he presented a neAV feature. He Avas shriveled like an old man; his eyes were sunken; he Avas cold and mottled Avith bluish spots. His breathing Avas sIoav, he cried a good deal and dreAV up his knees as though the abdomen hurt him. On ex- amination I found his mouth full of those white specks, indicative of thrush or the premonitory symptoms of thrush. He vomited several times and gave me the idea that the disease Avas irritating the stomach, if it had not reached it already. I am convinced that he Avas born Avith it and that it Avas due to a great consti- tutional debility, disarranged assimilation, and ferment- ing principles, Avhich always arise from want of proper physical organization; it, indeed, arose from an unor- ganized animal chymification. It Avas temporarily checked by Avashing the mouth Avith a solution of na- trum bisulph. 3 i to f i of Avater. 252 PROGRESSIVE MEDICINE. . R. Soda Borax, 1-dec. grs. xxiv. M. chart., xxiv. Dose—one poAvder every tAvo hours. The mouth Avas washed after taking the bottle. The child improved for two or three days longer but the mother felt uneasy. His agitation, cries and apepsia, Avith fre- quent passages, gave the alarming pathognomonic symptoms of aphetous condition of the stomach and boAvels. His abdomen was SAvollen and passed much gas. The evacuations were mucous Avith streaks of blood; the pulse Avas thready and the features indicated exhaustion and adynaemia. The faecal mat- ter Avas covered Avith a white aphteous matter. The treatment demonstrated from the various changes, that it Avas Avell chosen; had not the great physical dis- order prevented nature from regaining sufficient vigor to overcome the disintegrating process of mal-assimila- tion, there Avould have been a hope of recovery. All alimentation was of no advantage Avhen heterogenous formations Avere originated in the animalizing fluids themselves—heteroplastic-lymphoma. Proteous disease was unchangeable and beyond human poAver. We must observe that this is different (pathologically) from follicular stomatitis or enteritis, Avhich are condi- tions of much milder form, being idiopathic, or sympto- matic, from some other cachexia, hence fomenting dis- eases ; Avhereas inherited thrush is the result of animal dissolution like gangrene. I changed milk for animal food and gave him sulphurous acid, kali chloras, sweet oil, glycerine, etc., but only Avith temporary relief. He died at the end of a month, having lived longer than any one could possibly imagine. He died of star- vation and decay. He Avas a perfect mummy after death; even the bones seemed to have shrh'eled aAvay (Aphteous-Neonatorum). I luive seen a good deal of this disease in Hospital children, Avhere the little unfortunates inherit all sorts DISEASES OF CHILDHOOD. 253 of constitutional taints. Much can be done for those cases Avhich are idiopathic and available to treatment. We are indebted to Dr. Berg, of Stockholm, who made a microscopic research of the pathology of the disease in 1842, and to Dr. Jenner, Avho has suggested the treat- ment of sulphite of soda, Avhich being decomposed by the acid of the saliva, it becomes sulphurous acid, Avhich destroys the parasites. 254 PROGRESSIVE MEDICINE. CHAPTER VII. ERUPTIVE DISEASES, SCROFULO-DERMA, MAL-ASSIMILATION, GASTRO-HEPATIC AND GASTRO-INTESTINAL ACRIMONY. Efflorescence, pathologically speaking, is a significant term, full of meaning and closely applied to its purpose. •It indicates—to break out, and is applied to floAvers in bloom; it is indeed, the natural sequence of an inward fermentation (zymotic diseases) Avhich must sooner or later creep through the lymphatic absorbents, and make its Avay to the surface, or Avithin the cutis vera and the outer surface. There are many such diseases, of various intensity and virulency. Some are spontaneous, idio- pathic ; some constitutional and inherited, and others symptomatic. They are the result of either \-egetable or animal de- cay; from hydro-carbone or hydro-sulphurated exhala- tions, or from arnmoniacal and nitrogenous mephitic exhalations (animal decay). The vegetable or animal fungi are either spontane- ously generated and existing in the protoplasma,or else introduced by effluvial gases proceeding from alluvial soils or meteorological influences. These diseases may be indigenous, or brought from other places. They are the offsprings of uncleanliness and neglect. Sometimes are spontaneous, external, uncomplicated Avith any constitutional disorder. They disseminate rapidly Avhere there is a prolific soil to in- vigorate groAvth, and climeric influences to assist them. Moisture alone does not ahvays produce malarious diseases; for in highly rocky places the most destructive ERUPTIVE DISEASES. 255 effluvia is produced by the rain falling upon the hot rocks, Avhose crevices are full of fungi or auimalculi, Avhich being disengaged by the influence of the rain produce malarious gases; although moisture Avith vegetable decay forms combinations of gases poisonous in the extreme. And again, A^ery dry atmospheres Avith electric influences combined, decompose animal matter, change animal fluids, and neAV compositions are formed Avhich are deleterious to organization and life itself. I find it necessary to confine myself to a certain class of examinations Avithin the boundary of neAV cutaneous diseases. These are subdivided into genera, atrophia and hypertrophy of the lymphatic vessels and glands from Avhich these various eruptions often originate, and also from gastro-hepatic and gastro-enteric crudities with neurotic complications. From these physio-organic disorders rise mal-assimilations and proteinaceous diseases. There are a feAv idiopathic eruptions Avhich are super- ficial, and that create but temporary disturbances, like erythema solares or simplex: erysipelatous inflamma- tions from heat, cold, moisture, or chemical causes. The second class are generally of an inflammatory character and they have a regular course, pathological peculiarities, and are not dispersed through certain physical morbid phenomena. The third class are those that are inherited or pro- duced by certain physiological disorganization, hence constitutional cachexia; these are generally chronic in their nature and tendency. The anatomy and physiology of the cutis is as folloAvs: 1. Dermis, a cellular canvas, demise and fibrous, protect- ing the capillary vessels, the lymphatics, the nervous filaments, and papillae. 2. The organ of touch is formed by the termination of the nervous system. 3. The sudorific apparatus. The organs of secretion and ex- cretion Avith the sudorific canals. This apparatus is 256 PROGRESSIVE MEDICINE. composed of glandular parenchyma or spongy secreting glands, and the excretory canals arise among them as conductors of the sudorific fluid, Avhich are the channels by which evaporation takes place. 4. Absorbents; these resemble the lymphatics. 5. The mucous appar- atus. 6. The pigmentum. It is manifest to the most casual observer that such a variety of actions and effects must necessarily be sub- ject to a great number of derangements. Doctor Plumbe observes " Of those deviations from health Avhich Ave find frequently, diseases of the skin form no inconsiderable portion. Debility is the charac- teristic of a very large portion of these, Avhile repletion and disorder of the digestive organs arising from irregu- lar habits give occasion to many others." And this theory confirms much that Hahnemann has said in his Avritings on Psora; but of course he was ridiculed and persecuted just because he had the cour- age to advance a neAV idea. Much that is obscure in Hahnemann's Avritings is due to German mysticism. They are on the one side fond of the profound and the inexplicable, Avhile on the other they are often practical and materialistic; the tAvo extremes are real German failings. According to Hahnemann, every born human being had some kind of psora. Had this great reformer said that, in animal economy there Avas a latency for some dyscrasia Avhich exists in the ichorous juices of the scrofulous diathesis, the statement would have been accepted. But surely every child is not born Avith a psoric cachexia, nor scrofulous diathesis; it Avould be absurd to suppose such a thing. Strumous diseases appear under a variety of causes and pathological lesions, namely, Adenitis, mesenteritis, ulcers, abscesses, ophthalmiae, cutaneous eruptions, mor- bus coxalgia, tubercular consumption, etc. The dia- ERUPTIVE DISEASES. 257 thesis of the patient, the predisposing idiosyncrasies, and the exciting and enduced causes, are so many factors in the nature, progress and result of the disease which should not be thought of lightly; and it is only Avhen Ave make ourselves Avell acquainted Avith these sources of the disease in question, that a logical treatment can be arrived at Avith any chance of reasonable success. These different species of disorders are well de- fined by pathological descriptions, and from that and a thorough knoAvledge of the origin of the malady Ave are prepared for a successful attack upon the enemy. The acne simplex is an eruption of the sebaceous glands (meaning the summit of an efflorescent disease), has its pathognomonic symptoms both objective and subjective different from the acne punctata, indurata rosacea, yet the variety is the offspring of the same evil, namely, constitutional debility, and hence acrimony of the fluids Avhich remain unorganized or mal-assimi- lated, to be throAvn to the surface in some peculiar form according to the diathesis and idiosyncrasies of the in- dividual thus affected. This, hoAvever, is not the psora of Hahnemann, Avhich is generally a parasitic disease arising from vegetable or animal decay or the result of fermentation of either animal or vegetable matter, and hence animal or vegetable animalcules, impregnating the atmosphere and thus infecting the animal economy. Psora might also arise from Avant of cleanliness, from Ioav and poor diet, and from inheritance. But the acne requires only a simple and hygienic regimen, it seldom being necessary to have recourse to any medicine. Although idiopathic and simple eruptions are often met and treated successfully, yet, at times they change and become intensified and complicated by some con- stitutional taint unforseen and unsuspected. In these peculiar cases even erythema, the simplest of all the inflammatory eruptive diseases, may meet with 258 PROGRESSIVE MEDICINE. some predisposing and latent dyscrasia and thus become an eczematous fermenting exanthema; and vice versa, an eczematous eruption may terminate in a simple ery- thema, so that Ave cannot Avell determine Avhere and hoAV one disease Avill commence or end. One form may com- mence from the simplest and end in a serious kind of exanthema simply from a constitutional cachexia. But these two genera are merely phlogosis, one being simply the higher grade of the other. Eczema solares and humidum proceed as their names fully indicate from meteorological influences. We have no reason to accept the theory of Hahne- mann "that all eruptive diseases proceed from a consti- tutional psora or taint," as our present knoAvledge has clearly proved the fallacy of such reasoning, and given us a differential pathology and diagnosis. There are plethoric eruptions, or rather eruptions proceeding from plethora, as Avell as from adynemia; and again there are also eruptions arising from both hyperesthesia and asthenia, and are indeed constitutional—and yet they are not parasitic in their nature, and therefore patholo- gically speaking they differ Avidely from psora or the itch of Cullen. Even a simple eruption obstructs, often, the evapori- zation of the body and thus interferes Avith the normal physiological process of the economy. The idiopathic cutaneous diseases are classified as folloAvs: sthenic and asthenic, neuro-sthenia, neurosis or adynaemia. Women of great sensibility are prone to neuro-sthenia, others to adynaemia. These often suffer Avith cutane- ous irritabilities and hyperaemia Avith more or less of some kind of eruptions, and the cure depends A'ery much upon a correct diagnosis, as the causes are dissimilar, consequently the treatment must be different. Fre- quently such morbid conditions attack the genital or- ERUPTIVE DISEASES. 259 gans, and Ave find Avomen, especially those of a nervous constitution, suffering with vaginitis. Scrofula-Derma.—From this term Ave at once can place the morbid trouble in the lymphatic system and the blood. The lymphatic absorbents of the dermis are frequently involved in cutaneous diseases, hence the name of scro- fulo-derma; and these morbid conditions may be either acute or chronic: 1. Plethora lymphatica Avith turge- scence, 2. sthenic or asthenic The nature or type of the diseases and their peculiar classifications are the true mode of learning the pathogeny of morbid affec- tions; and it is indeed particularly necessary in the great vrariety of cutaneous disorders. Here is a\ here Hahnemann has erred in his great Avork on homoeopa- thic practice. In these cases of scrofulo-derma Ave find a condition of hetero-plastic disease diffused through the lympha- tics, of an ichorous, crude, mal-assimilated albuminoids (Proteinaceous disease), and all the vessels, glands, and lymphatic ganglia are thus either atrophied or hyper- trophied, gh'ing those pathological eAadences in the form of cutaneous diseases, and besides causing an hyperaemic condition of all the capillary A^essels sur- rounding them, thus an acute or subacute capillary con- gestion is the result. Much has been said about faulty-nutrition, chyme, and chylification, as the proximate principles of disorgani- zation of the physical forces, phenomena and metamor- phosis. Inasmuch as the excernent and secernent systems have the absolute endoAvment of organizing the elements of nutrition, adding materials to the proteine compound, it must be obvious to us that Avhen those absorbents and refiners secernent as itAvere, animalizingas the fluid proceeds, Avhen these are feebly developed, or are sur- 260 PROGRESSIVE MEDICINE. charged Avith elements not assimilated, that the tissue and blood must be naturally impure,—hence scrofula. Lupus Exedence/rom the non-Exedence.—The former is more confined to the head and face, and perhaps less intractable; Avhile the latter extends itself from the neck, shoulder and arm; it is more virulent and has a longer period. " Lupus exedence rarely attack the integuments of the chest, or the extremities; these are more frequently the seat of Lupus non-exedence."—Plumbe. The divided opinion of medical Avriters upon this peculiar disease has been, Avhether it Avas of a scrofu- lous nature or free and disconnected from it. The question has been often discussed Avith more or less ability on both sides; but it is noAV regarded as a dis- ease proceeding from a strumous diathesis, although, it may differ in certain objective manifestations, yet the pathognomonic symptoms are those of constitutional taint someAvhere. It is said that many cases of lupus occur in people of sound health, and avIio have never suffered from any cutaneous or chronic troubles Avhat- ever. These are not points Avithout a certain force to the argument. Lupus, therefore, is not per-se, a scrofu- lous disease, although they admit that it may be con- nected Avith scrofula and erysipelas or syphilis; but it is also argued, and Avith a strong sense of logic, that, even a pure, strong constitution may have subjective predispositions or latencies, Avhich only require certain exciting causes to develop some of the most unsus- pected dyscrasia, such as, tuberculosis, Avhich afterAvards develops into galloping consumption, cancers, malignant tumors, ulcers, diseases of the bones, etc. The acrimony of the gastro-enteric juices is really the factor of this malady; and these conditions may be inherited, excited or induced. And Avhy is it that this lupus exedence is to be found more frequently in people from the age of childhood to ERUPTIVE DISEASES. 261 manhood, and seldom after forty? It is obvious that the lymphatic diseases are more generally developed in the tender age, and the age of development, than after- Avards, Avhen the physical and organic functions have fought the battle out, changed the ichorous secretions and returned to a comparative normal condition. Are not the young more prone to diseases of the alimentary organs and the vis-vitae than older people? Surely many a delicate person if he can only reach the other side of thirty or forty, is good for many years after, and the reason is Avell knoAvn to physicians. And again, those people aat1io live on sour food, tainted meats, and breathe animal mephitic poisons are more prone to these diseases than those living in comfort. And Ave see also those that indulge in spirituous liquors, fermenting Avines, rich, greasy, nitrogenous diet, suffer Avith gouty dyscrasia—or lithiasis; as Avell as those Avho indulge in delicacies, which render digestion and as- similation out of the question. They thus produce accumulations of acidities in the primce vie, changing healthy chyme into acidulous chyle and thus the pheno- mena of physiological metamorphosis, is changed into an unspeakable fountain of anomalies. It is therefore, in my opinion, a disease of a proteous nature, or hetero- plastic lymphitis. CLINICAL CASE I. Mr. B., age sixty-tAvo, of a nervo-lymphatic tempera- ment. Small frame but apparently Avell and Aviry. He suffered no pain and no debility. He had a gray Avhite cicatrix under his right eye extending to the alae nasi; it Avas a thin shining skin Avhich indicated a poor reticu- lated structure of the cutis, and its softness denoted a Avant of healthy tissue underneath. The eyelid Avas someAvhat everted from the former corroding attack of lupus exedence. Physical Examination.—The skin looked unhealthy. 262 PROGRESSIVE MEDICINE. The heart Avas frequently functionally irregular and ex- cited ; lungs Avere sound but the liver Avas torpid, and the stomach very delicate. The chylopoietic v-iscera was evidently disturbed in its organizing functions, and the animalization of the elements of nutrition Avas de- defective in the extreme. He had a large head and small grey eyes. I found a chronic enlargement of the cervicle and submaxillary gland. He Avas ahvays a good liver, and often abused the privilege of the table; smoked and used Avines ad libi- tum. The capillary circulation was sIoav. He kept late hours, and confined himself to reading and intel- lectual pleasures. Years before he suffered agonies Avith a complete retrograde process of all the functions of alimentation; he became so much reduced in his physical and vital forces that his life Avas in eminent danger. Semiology.—After a protracted illness of dyspepsia, Avhich nearly carried him to the grave, he found that, Avithout any preliminary symptoms, he had a small scaly eruption under the right eye, Avhich Avhen the little scab Avas removed, secreted an ichorous fluid, and that it had various points as large as a pin's head, hard and in clusters; he paid little attention to it until he found that it Avas extending and deepening. His digestion Avas entirely out of order, but not so much so as it had been; hoAA-ever the disease made rapid progress and became very alarming, ulcerating a large space under the eye. He lost flesh and vitality. His appetite left him and he became the victim of a morbid imagination. Insomnia soon set in, and he resorted to all the pana- cea of narcotics, Avithout avail, but rather Avith injury. Etiology.—Scrofulous diathesis Avith a malignant dys- crasia. Predisposing cause, a sedentary life. Exciting causes, indulgence in the table, smoking and late hours. When I saAv the gentleman he had had a return of it, after twenty years of comparatively good health. ERUPTIVE DISEASES. 263 The hygienic laAv Avas thoroughly observed by him- self. I only added salt in the Avater he bathed in and at times potassia, so as to add plastic force to the blood. Medical Treatment.— R. Liquor Potass arsen., 3-dec. gutt., xii. Aqua distillata, ? iv. One teaspoonful four times a day; and locally I pro- scribed : R. Acid tannicum, 3 sj. " benzoicum, 3 sj. Collodion, f ii. This application made a protective emplastrum, which excluded the air. He recovered, but is liable to a return at any moment, being a constitutional dyscrasia. CLINICAL CASE II. This is a case which is singularly interesting, being rather rare in practice, namely, acute-bilious eruptive fever. I met this case at Norfolk, Virginia, during the Avar. Physical Examination.—I found a large, well-developed man Avith good lungs and heart. I also found an en- larged liver painful to the touch. His kidneys Avere ir- ritable and urine scanty, with heavy sediments of lith- ates and urea, specific gravity 1030—reaction acid, and at the same time containing biliary pigmentum. Pulse 130, large in volume and full in force. Bowels constip- ated, although he had taken much medicine for them. Tongue coated yellow, white and slimy, conjunctiva of a yellowish color. Skin dry and infiltrated Avith im- purities, and here and there I found red spots as large as a five cent piece. He felt very sick and complained of restlessness and severe headache. Semiology.—Fever, thirst, constipation, nausea, hot and cold sensations alternating, somnolence without 264 PROGRESSIVE MEDICINE. rest or real sleep; fever Avorse at night. Dry skin, headache, dispondency, flatulency, etc These accom- panied Avith the spots above described completed the symptoms truly pathognomonic to hepatic congestion folio Ave d by capillary engorgements of the system, Avith impurities remaining in the blood. The capillary venous circulation in the liver Avas sIoav and the pro- cess of freeing the excrementitious elements of the venous circulation Avas imperfect, hence, biliary pig- ment in the urine, skin, conjunctiva and stomach. The ductus communis Avas inflamed and tumefied in consequence, and the bile could not freely pass into the intestinal canal. There Avas retention as Avell as suppression, the latter as a physico-vital debility. The debility of the organ disabled it for the Avork of purify- ing the blood from the bile and other excrementitious elements. Etiology.—The man had been exposed to all the vic- issitudes of the life of a soldier, exposure to heat and cold, moisture and bad Avater and food. These causes Avere alone sufficient to bring about a certain amount of physiological disarrangement of the assimilating pro- cess. The liver suffered from anaemia and ichorous ele- ments ; its physical and vital feebleness prevented the organ from that activity necessary for the process of purifying and eliminating the effete materials from the venous circulation. These organic disabilities caused the fever, the eruptions and all the other complications. Medical Treatment.—A Avarm bath accompanied by draught of Avarm Avater. Hot poultices to the liver. R. Natr. phosph., 1-dec. grs. lx. M. chart., xxx. R. Belladon., 1-dec. gr. lx. M. chart., xxx. Dose—one poAvder every hour, alternately. I must premise that the man had taken calomel and blue-mass ad libitum with castor oil, etc. ERUPTIVE DISEASES. 265 Diet.—Generous as soon as his appetite Avas restored but during the fever I gave him barley and rice Avater with milk. Next day he had free discharges from the boAvels of a greenish yellow color denoting a pungency and an acrid- ity of the excrementitious elements sufficient to produce some physical disorder. He felt better; the pulse Avas softer and less in volume; he rested better, and the skin gave evidence of moisture. The urine was heavily laden Avith phosphates and ammonia, It Avas evident that we were on a fair Avay to help the vis medicatricae naturae to throAV out the invading poisons. I continued the same treatment during the second day. On the third day I found the patient much improved. Urine more abundant and lighter in color. Tongue partially clean. BoAvels continue to moAre. Appetite slowly returning. Free perspiration. The headache left him and the pulse Avas much more natural. The spots Avere disappearing and the capillary congestion visibly diminished. I kept up one bath a day and hot applications to the liver Avith occasional Avarm drinks. R. Natrum phosph., 3-dec. gr. xxx. M. chart., xv. R. Bryonia alba., 3-dec gutt. xxiv. Aqua distill., f ii, Dose—one poAvder alternately with a teaspoonful of the liquid. Diet.—Beef broth Avith vermicelli. Cocoa in the morning Avith toast. In the evening he was given ren- net made in fresh milk. On the fourth day all the symptoms and the fever Avith the portal and capillary congestion disappeared. I prescribed R. Aloes, 3-dec grs. xxx. M. chart., xv. 266 PROGRESSIVE MEDICINE. Dose—one poAvder every two hours. One tumbler of Congress Saratoga Avater morning and night. On the seventh day I ordered rare beef or mutton chops for dinner, port Avine, beef broth Avith rice, and rice Avith milk. He did Avell and the case Avas dis- charged. In connection with this case I must add another. CLINICAL CASE III. A boy of 12 years of age, of a bilio-nervous tempera- ment. He had had several attacks of bilious derange- ments. His sister and father suffered from organic disorder of the liver. His mother Avas health)', and Avas of a lymphatic diathesis, and never suffered Avith that dis- ease. He came to me several times with digesth-e troubles, connected Avith biliary complications. The chylo-poi- etic viscera Avas obviously feeble, and assimilation im- perfect, hence portal engorgement and synocal fever. These light deviations were easily treated and remoA^ed until he got Avet during the predisposing month of Sep- tember, and then he became dangerously ill. Physical Examination.—I Avas called to see him after a feAv days of sickness had elapsed, and I found him in the folloAving condition: High feA'er, pulse 130, full, temperature 101, and skin dry and full of a yelloAvish pigment. Perspiration 25 per minute. Urine very scanty and of a broAvnish color, with a sediment of heavy phophates. Lungs were sound. Cardiac excitement. Stomach and intestines tender and inflated. Tongue heavily coated, broAvnish white and dry. Liver enlarged and painful; joints painful and covered with reddish spots. His Avhole body and face Avas also covered with them. He suffered from insomnia and ERUPTIVE DISEASES. 267 with great pain all over his body. A few days after my first visit I was taken sick and another homeopathic physician Avas called. He pronounced it meningitis and spotted fever, on the ground that the patient seemed to have tenderness along the spine as Avell as the spots. He attended him for a feAv days Avithout success, Avhen I became convinced of his palpable error of diagnosis, and took charge of the case myself, and convinced him of his error and directed him to pursue my treatment as I Avas physically unable to attend. Semiology.—Great thirst. Devoid of appetite. Pain all over the body, so much so that he could not be moved Avithout suffering. All his joints Avere covered Avith red spots and SAvollen. BoAvels constipated, and secretions (for faecal matter) Avere devoid of bile. Urine scanty. Skin dry. High fever and Avorse about four o'clock p. m. till mid- night, Avhen it abated. He Avas very fearful of his con- dition, and cried and scolded. His whole nervous sys- tem Avas in a state of irritability. Etiology.—The predisposing causes Avere: 1st. Bil- ious temperament; 2d. The feeble digestion predis- posed him to acrimonies of the excrementitious elements, mal-assimilation and impure venous blood: 3. Organic debility of the liver. Exciting causes Avere irregularities in diet and ex- posure to cold. From the nature of the symptoms and the pathologi- cal condition of the economy I pronounced it a case of bilio-rheumatic fever; accompanied by portal congestion and capillary engorgement. Medical Treatment.—As the patient had not been re- duced by strong medicaments, I hoped that with a de- cisive homeopathic treatment and good judgment, the case Avould terminate favorably. I prescribed aconite and bryonia for twelve hours without the least benefit. 268 PROGRESSIVE MEDICINE. I continued the same treatment for tAvelve hours longer without any effect either on the fever, spots or liver. On the third day I ordered a cataplasm of hot bran over the liver followed by R. Mercurius dulcis, 3-dec grs. xxx. M. et devid chart., xx. R. Belladonna, 3-dec. gutt. xii. Aqua distill. ^ iii. Dose.—One poAvder every hour alternately with a spoonful of the liquid. On the next day he Avas someAvhat better. The urine Avas more abundant. He perspired, slept better and the fever Avas abated—pulse 120. In connection Avith the above, I ordered hot marsh-malvadraught, as a dilu- ent of the acrid secretions, having also the medical property of affecting rheumatic and various troubles. The fifth day, having exhausted the action of the above remedies, I prescribed R. Aloes, 3-dec grs. xxx. M. chart., xx. R. Rododendron, 3-dec. gutt. xxx. Aconite nap., 3-dec. gutt. xv. Aqua pura, 3 ii. Dose.—One powder every hour alternately Avith a teaspoonful of the liquid. In connection I gaA'e him half a tumbler full of Vichy Avater morning and evening. On the sixth day he had three foetid evacuations of the boAvels. The urine Avas clear, pulse 100, tongue much improved, and the spots disappearing. I left the case in charge of the other doctor, Avith the condition that he should pursue my course of treatment, varying only the remedies and giving magnesia phos- phatis 3-dec. and natrum phosphatis as the finishing touch. The patient got Avell at the end of four Aveeks. CLINICAL CASE IV. Mrs. Van, age forty, of a nervo-bilious temperament, and of a delicate physical development. She had had ERUPTIVE DISEASES. 269 three children, tAvo of Avhom Avere living. Her work Avas that of a farmer's Avife—hard and confining. She lived in the true rural and primitiA^e style—simple diet, hard Avork, early hours, and a retired life. She Avas emaciated, feeble, and had a difficult digestion. Her appetite Avas poor and her boAvels Avere constipated. She often suffered with hypochondriasis and paroxysms of nervousness. Physical Examination.—Her complexion Avas preterna- turally dark, the skin dry and furfuraceous. Heart irri- table but healthy; liver hard and rather contracted; the nutrition of the organs Avas imperfect. Kidneys normal. Pulse small, and asthenia and adynaemia Avere prominent features in her general appearance. Semiology.—Apepsia. Heavy feeling at the epigas- trium after eating. Eructations, constipation insomnia, headache, Avant of energy, and a general feeling of malaise. Assimilation Avas imperfect, and the process of histogenesis Avas greatly enfeebled. Anaemic symp- toms, namely, small Aviry pulse, heart quick in action and capillary circulation very feeble. There Avas par- tial organic inertia of the functions of the liver. She complained of an itchy eruption over her face and arms, and sometimes covering the chest. She Avas very Aveak and nerA'ous. She had no fever. Her tongue Avas coated Avhite, and covered with a thick fur, and tremulous. Her general health Avas apparently disordered. She had spots of a dark reddish color over her face, and they Avere erysipelatous in their nature. They burned and itched after going to bed. Etiology.—1. Physical feebleness. Her Avhole econ- omy Avas beloAv the average of a normal stand of force (inanition). 2. Her Avork Avas too exhausting for the recuperative process. 3. Innutritious food. 4. Tea and coffee ad libitum. 5. Confinement to the house. The origin of her pathological condition Avas Avant of pep- tones and of digestion and assimilation from physico- 270 PROGRESSIVE MEDICINE. vital debility of the economy, increased by overwork and injudicious diet. This brought about emaciation, asthenia and anaemia (poverty of the blood and nervous exhaustion). Taking the above description of the case, Ave cannot fail in our diagnosis. Anaemia and neuro-sthenia, both proceeding from a general Ioav vitality of the Avhole organizing process. The liver AA^as inactive from Avant of physical force, being, like the rest of the system, an- aemic. The eruption proceeded from a capillary stasis or inability to push vis-a frontis the circulating fluid, and this Avas produced by portal and vaso-motor debility. Noav, it Avas evident that the excrementitious materials could not be either normal or thoroughly eliminated. The functions of injestion and ejestion Avere greatly diminished, so that the wdiole economy Avas in a state of abnormal transition. Medical Treatment.— R. Belladonna, 3-dec. grs. xxxii. M. et fiat chart., XA'i. R. Quinia sulph., 3-dec grs. xxxii. M. chart., xvi. Dose—One poAvder every two hours alternately. Hygiene and Dietetics.—A tepid bath Avith salt every other night. Generous diet—beef, mutton, old port Avine and vegetables. At the end of a Aveek she returned already improved. Second Aveek I gave her nux 3-dec. and lycopodium 3-dec. She Avas evidently benefited by the treatment. The boAvels moved regularly, appetite Avas better, pulse fuller and normal, and the tongue clear, the spots having disappeared. Yet she Avas anaemic and therefore I prescribed Iron peroxidi, 3-dec and aloes, 3-dec. during the week. Diet and bathing the same. On the fourth Aveek I prescribed natrum phosph., 3-dec. and ferrum peroxidum also the third trituration. She recovered completely. ERUPTIVE DISEASES. 271 CLINICAL CASE V. Mr. P., forty-eight years old, of a bilio-nervous dia- thesis, Avith venous plethora, namely, hemmorrhoidal tumors and portal feeble circulation. His constitution denoted feebleness of the co-ordination of organic functions, Avith adynaemia-. The peptones Avere defective in quantity and quality, hence emaciation. The chemico-physiological process of digestion was seriously impaired, and the protean compound Avas Avanting in animalization and force. He had large hands and feet and Avas anaemic He suffered for years Avith hemorrhoidal tumors and fluxus hamorragic, which confined him to his bed for AA'eeks on account of the loss of blood. His general appearance Avas that of cachexia and scrofula. There was an evident lymphatic atrophy Avhich in- terfered Avith the functions of absorption and secretion. The albuminoids Avere scantily and imperfectly assimi- lated, hence emaciation and anaemia, and at the same time the Avhite corpuscles were greatly diffused through the blood (leucophemia) seriously impoverishing the process of animalization. Physical Examination.—I found my patient in bed, looking fearfully emaciated and of a yelloAv-broAvn color, Avhich gave me at once the thought of disease of the chylopoietic viscera, connected Avith organic disease of the liver. The liver Avas small, hard and tender. Ab- domen SAvollen and tympanitic. Stomach retracted and tender on percussion. Heart quick and agitated and the volume did not indicate strength. The skin Avas dry and rough and filled with a broAvnish yelloAv pig- ment. Eyes dull. Tongue heavily coated. Tempera- ture very Ioav. Inanition from mal-assimilation. He suffered Avith an eczematous eruption and hemorrhoidal tumors, etc. 272 PROGRESSIVE MEDICINE. Semiology.—Weak pulse—90; temperature, 97. Apep- sia, headache, insomnia, great exhaustion, cold extremi- ties, pain in the back, eructations of a soury bitter nature, and unable to attend his business. He had con- stipation, urine heavy—1029, bilious and scanty, and hypochondriasis. He was miserable generally and Avas threatened with physical disorganization. He had small grey eyes, large head, intelligent, and of a scrofu- lous diathesis. Etiology.—1. Physical debility and hence organic derangement. The feeble A-enous circulation predis- posed him to engorgements and stasis of the portal cir- culation, due to Avant of force; the Aaso-motor nerves Avere also Avanting in activity. 2. The predisposing causes Avere a sedentary life, Avhen young, being a school teacher. 3. Country heavy diet, Avant of proper bath- ing, excessive smoking and sleeping on a feather bed in a closed room. It Avas indeed a complex case as the pathognomonic symptoms Avere organic and physical, nerA'ous and san- guine. There Avere some organic troubles of the liver and lungs, atrophy and anaemia hepatica, also tuber- culosis pulmonalis. Medical Treatment.—Could any heroic treatment have availed here ? Avould it haA-e been at all advisable to prostrate his already small recuperatiA'e poAver ? I believe any school of medicine Avould recognize and ap- preciate the difficulties Avhich Ave re certainly insur- mountable by such a treatment; a treatment that demanded a stronger vitality and recuperative poAver. It Avas obviously a difficult case to treat, where proper judgment Avould have to be exercised Avith the utmost care. 1. Reviving general principles of vitality and nutrition. 2. Diminish the venous and portal sluggishness. 3. Lessen nervous irritability. 4. Excite organic action. 5. Increase the process of injestion and ejestion. On these five points I began my plan of treatment. ERUPTIVE DISEASES. 273 R. Camphora, 3-dec gutt. xxiv. Aqua distill., f ii. Dose—one teaspoonful every hour. Capillary Stasis.—The pathogenesis of camphor shows the symptoms of prostration, coldness, weakness of the cerebrum, burning at the stomach, irritability of the genital organs, and increase of biliary activity. This remedy I found a great agent for vital exhaustion, or- ganic enertia and vascular inactivity. It acts at once on the heart, cerebrum, secretions and vascular system. At the same time I ordered sheets wrapped round the body, which had been previously Avet in tepid salt water. Hygiene and Dietetics.—Beef broth and rice, clam soup, oyster broth, birds, eggs and Avine. The sheets were left upon him until full reaction took place; then he Avas to be rubbed and covered Avith blankets. On my return next day I found that the patient had slept Avell, and that he felt more comfortable. His pulse Avas softer, sloAver and fuller. The treatment Avas pursued Avith the aim of producing a derivative action to the surface through the process of ejestion of the excrementitious matter. The fourth day I found my patient sitting up and looking as though there were two great agencies at work, and he patiently aAvaiting the result; one inan- ition, the other the inherent vis medicatricae naturae. Both existed, and the question Avas Avhether the dyna- mic force would be sufficient to kindle a feAv more sparks of vitality and thus increasing, as it Avere, atomically the physico-vital forces. These are times when the physician stands beAvildered looking on the great strug- gle betAveen nature's process of re-organization and support, on the one side, and decomposition and decay on the other. In this condition of great physical transition, the phenomena of nature's resources are most Avonderful and often secure recovery. 274 PROGRESSIVE MEDICINE. Medical Treatment.— R. Belladonna, 1-dec gutt. xii. Aqua distill., f ii. R. Phosphorus, 3-dec. gutt. x. Aqua distill., f ii. One teaspoonful alternately every tAvo hours. Here we have tAvo great agents: belladonna the great vaso-motor re-invigorator, and phosphorous, the vital force invigorator. I had a good opportunity of observing the effects of these tAvo agents, and indeed, I Avas fully convinced of their perfect medicinal restorative poAver. The gentleman Avas noAV on the sixth day of the treatment, and the line Avhich Avas so narroAvly separating life from death Avas happily passed. The belladonna and phosphorus together Avith a pre-existing hygienic and dietetic treatment brought about the vital re-action by forming neAV sparks of life, and so neAV elements of force Avere added to the ebbing vitality. It is indeed a great source of satisfaction to feel that your cares and anxieties have been so happily reAvarded. Eighth day. Noav I considered the patient out of dan- ger, but hoAV much strength he would gain was a' question beyond human calculation. Having been two days on belladonna and phosphor- us I let the agents have their full scope of action upon the system. I omitted the remedies, and gave him solid food— Beef-steak, roast beef, Avine, eggs, game, etc., Avith a sponge bath every night at the temperature of 75. Tenth day. The impetus once given, together Avith the anti-inanition dietetic treatment, a great salient point Avas obtained. I ordered R. Phosphorus, 3-dec. gutt. xxiv. Aqua distill., f ii. R. Aloes, 3-dec grs. xl. M. chart., xx. ERUPTIVE DISEASES. 275 Dose—one teaspoonful of the liquid, alternately with the poAvder. The aloes I used for its specific action upon the hem- orrhoidal veins and portal circulation. Fourteenth day. The improvement continued with- out intermission. He Avas able to go about the house and felt much invigorated. I ordered him out to drive in a soft cushioned carriage. His digestion improved; assimilation and histogenesis became more natural. His pulse became stronger, he slept Avell and his brain grew stronger and more active. He also improved in looks; the skin lost that yelloAvish broAvn color. The capillary circulation gave evidence of having become normal. The liver and eczema both Avere on the road to recov- ery. The lungs did not trouble him, but the seed of the evil remained permanently located there. The boAvels moved regularly. Sixteenth day. R. Ferrum peroxidum, 1-dec. gutt. lx. Aqua distill., f iv. R. Natr. phosph., 3-dec. grs. lx. M. chart., xxx. These medicines he continued for tAvo wreeks with a decided improvement. At the sixth week I gave him Acid hydrochloric and Magnesia phosph. at different times. I then added more of those elements of Avhich the system stood in need: e. g. Quinia, Nux vom., Bismuth and Bryonia. During this time he had resumed business and looked a different man. CLINICAL CASE VI. A young man, tAventy-four years old, of a fine phy- sique, perfectly healthy, Avho took great deal of physical exercise by boating, hunting and fishing. His trouble Avas a disease in the matrix of the nails 276 PROGRESSIVE MEDICINE. groAving normally for a short length, then dividing or separating in tAvo, and thus becoming brittle and break- ing off close, making the finger look unnatural. His mother Avas a delicate, nervous Avoman, Avith more brain than physical force to support it; she suffered for years with cracked fingers at the tip, and at times Avith small reddish spots on the body. She Avas anaemic, and gene- rally feeble. Assimilation and absorption Avere difficult and imperfect, hence her constitutional difficulty. I pre- scribed for the young man R. Silicia, 3-dec. gr. lx. M. chart., xxx. R. Hepar. sulphur, 3-dec. grs. Ix. M. chart., xxx. Dose—one poAvder every three hours alternately. In tAvo months he reported Avell. The mother I treated differently. I gave her R. Natrum-phosph. et quinia sulph., changing for R. Ferrum peroxidi, 3-dec. gutt. xxxx. Aqua distill., f iv. Dose—one teaspoonful every two hours alternately. Again, R. Magnesia phosph., 3-dec. grs. lx. M. Et fial chart., xxx. She improved in general health; and the cracks filled up. Her color became healthy as her digestion im- proved. R. Pujsatill., 3-dec. gutt. xx. Aqua distill., f iv. R. Lycopodium, 3-dec. gutt. xx. Aqua distill., f iv. Hygiene and Dietetics.—Bathing in hot Avater and bi- carbonate of potass tAvice a Aveek, I concluded the treat- ment with fresh air, country life and improved diet. In her case the treatment Avas to supply those proper- ties which Avere needed. She had evidently lost much of those substances that are necessary for the formation ERUPTIVE DISEASES. 277 of plastic materials, and the acrimonious secretions had produced an indescribable change in the blood. In her son's case there Avas a natural deficiency of the silicate and sulphate of lime, and by adding the silica and hepar. sulphur the case Avas cured on a physiological principle. CLINICAL CASES VII, VIII. Tavo children were brought to me suffering from crusta-lactea. They suffered Avith intense itching Avhicli produced much nervous excitement, debility and fever. It is generally accepted that the milk is the source of this evil; its fermenting principles, its caseine and butyric acid being so many elements predisposed to ichorous eruptions. Surely, the elements of nutrition and the process of digestion and assimilation are deeply involved in the organization of the animal economy, thus a poor nutri- tion can only have as a result an enfeebled physical de- velopment; but again Ave must also admit a certain proneness of diathesis, predisposing the system to im- purities and accumulations of the excrementitious materials, and this is the lymphatic diathesis. The idiosyncrasis of this system Avhen largely developed is inArariably that of increasing the absorbent process, Avithout, at the same time increasing the ability of ejes- tion, thus predisposing to plethora lymphatica, adenitis, and eruptive diseases. This theory is sustained by facts, and is based upon practical truth. The mother of one of the infants Avas scrofulous, and the other having happily more vitality, Avas endoAved Avith a healthy lymphatic organization. In both cases the children suffered alike, although by inheritance the symptoms Avere different. One had a defective and feeble organization, the other had abund- ant force, both physical and vital. The delicate child and the strong one, both suffered from two extremes. 278 PROGRESSIVE MEDICINE. It is obvious, therefore, that the two cases should have been treated differently; and for this very reason it is that, an empiric treatment is in all schools of medi- cine considered dangerous and unscientific. Medical Treatment.—For the first case, I prescribed both for the mother and child, R. Calc phosphorica, 3-dec. grs. lx. M. chart., xxx. R. Ferrum peroxid., 1-dec. grs. lx. M. chart., xxx. Dose—one powder to the mother every tAvo hours al- ternately. To the second I prescribed a vegetable diet for the mother, and the folloAving prescription for the child. R. Graphite, 3-dec. 3 i. M. chart., lx. R. Kali carbonic, 6-dec 3 i. M. chart., lx. Dose—one poAvder every three hours alternately; and to the mother Vichy water eArery morning. Hygiene and Dietetics.—To the delicate mother it is hardly necessary to say, a generous diet Avas prescribed and deemed as a part of the treatment : beef, mutton, oysters, birds, nitrogenous vegetables, cocoa, milk punch Avith Jamaica-rum, and salt Avater baths; and the folloAA'- ing medicinal agents Avere from time to time given: R. Magnesia phosphorica, 3-dec. 3 i. M. chart., xxx. R. Ferrum peroxid, 3-dec. 3L M. chart., xxx. Dose—one poAvder every two hours, alternately. And to the strong healthy mother the prescriptions Avere reversed: vegetables, fish and light animal food, Avith plenty of exercise and ripe fruits. I gave her baby R. Calc. phosph., 3-dec. 3 i. M. chart., xxx. ERUPTIVE DISEASES. 279 R. Natrum sulphur, 3-dec. 3 i. M. chart., lx. To be given first one, and when that was exhausted, begin Avith the other. These children both were cured and the mothers' health also improved. I sometimes found carbolic acid glycerole, or zincum oxydum glycerole good adjuvants for local applications; they soften the scabs, prevent the itching, and keep the air from irritating and causing more suppuration. 280 PROGRESSIVE MEDICINE. CHAPTER VIII. USEFULNESS OF ELECTRICITY*. From my experience, and that of many medical gentle- men in Avhose field of practice electricity has been em- ployed as a therapeutic agent, I have no hesitation in saying that it is one of the greatest panaceas for diseases of the organs of digestion and assimilation. It imparts force, motion, composition and decomposition. It in- creases heat, oxidation, circulation and organization. x It changes the juices, increasing absorptions and secretions. It eliminates the materiae morbi through the excremen- titious matter. It extricates organic engorgement and releases the organs from sanguineous stasis and torpidity of action, thus setting a vis-a-tergo-physical force to re- adjust physical equilibrium. Notwithstanding the quackery Avhich unfortunately has been obscuring much of the virtues of electricity as a medical agent, haA'ing diminished its Avell deserved reputation on account of the ignorance Avith Avhich it has been used and abused; yet it retains its usefulness in diseases Avhen properly applied. To secure success it requires several points: 1. KnoAv- ledge of its action, 2. KnoAAdedge of the disease Avhere it should be applied, for it cannot be used in all diseases indiscriminately, and 3. The proper current and its strength. It is indeed an agent of great ATalue in rheu- matism (not inflammatory), in gout (not acute), in neu- ralgia, in apepsia, in jaundice (hicterus), and in paraly- sis. As electrolysis in surgical operations, for tumors USEFULNESS OF ELECTRICITY. 281 and polypus, in calcareous deposits in the joints, and in fact in all the cases of locomotor ataxia, asthenopia, diploplia, etc With this agent, I cannot refrain from mentioning another Avhich is Avell-knoAvn and yet little used by the profession, namely, Avater. In acute eruptive diseases, in fevers of an inflammatory type, in inflammatory rheu- matism, pneumonia, bronchitis and Aveakness of the di- gestive organs Avhere the excretions are sluggish and strongly charged Avith animal poisons producing either exanthem, or organic pathological conditions, it may be used Avith excellent results. This agent is one of the best as an anti-pyretic and acts directly upon the dif- ferent A'essels, as well as upon the process of injestion and ejestion by quickening the activity of the absorb- ents and secretory organs. It relieves general plethora, sanguineous suggillations, and equalizes the physical Avith vital forces as Avell as the temperature of the body. With this agent Ave can combat yelloAv, typhus and typhoid fevers, scarlatina, measles, paludal fe\Ter, per- nicious fever and all malarial diseases. The reason is obvious, namely, that Avater properly used disengages the animal economy from the absorbed poisonous mole- cules of the effluvial gases, and eliminates them through the excrementitious matter in shape of urea, biliary secretions, lactic, carbonic and uric acids, and through the secretory and sudorific organs of the skin. The use of Avater is to be carefully estimated before subjecting a person to its influences. We must con- sider, 1. The general physical condition of the patient. 2. His strength and idiosyncrasies. 3. The nature of the malady and the reactive force of the patient. 4. The temperature of the Avater must be according to the pa- tients constitution, nature of the disease, age, sex, hab- its, season, etc. With these preliminary steps and cautions, Avater can serve as a great medical agent. 282 PROGRESSIVE MEDICINE. With it Ave must combine a suitable diet and medicinal treatment. I recommend these two great agents par- ticularly to the Homoeopathic physician, because ration- ality is his only course. I deem it necessary that the study of the process of alimentation should have a distinct chapter devoted to it in this wTork, because the proper dietetics is a thing of great importance to the sick, and invalids, being the pabulum upon which the recuperative process of nature greatly depends. EFFECTS OF MEDICAL AGENTS. 283 CHAPTER IX. THE DUAL EFFECTS OF MEDICAL AGENTS. This is not, perhaps, a theme totally new or altogether unknown to some of our Avriters on materia medica, and therefore I do not presume to enter fully or in detail into the subject; I simply desire to call the at- tention of both schools to some salient points Avhich are of great interest and usefulness to the practitioner of medicine. The subject might have been broached, possibly, by abler men than myself, had it not been for the fear that they might be ridiculed. Let us Avalk forward, no mat- ter if a feAv shallow-brained felloAvs cannot understand us and therefore delight in abuse and misconception. The vagaries of both schools are so great and their intolerance of anything that is foreign to their teaching is so overbearing that they Avould even shut their eyes to the grandest of discoveries were it to interfere Avith their theories. But it is possible to show that the faults of both are glaring and easily visible. One has the fault of an endless symptomology, in Avhich if true, one medicine Avould be sufficient for all the diseases that " flesh is heir to." The other is crude and has tried to simplify the practice by classifications AA'hich are con- stantly at variance Avith the pathogenetic effects and therapeutical results of medical agents; both are erring in the main from the true spirit of physicians, and are therefore antagonistic, bitter and sectarian. A unity of action and generous effort in the great work of scientific 284 PROGRESSIVE MEDICINE. medicine would be more becoming and beneficial to both. Why Hahnemann should have thought of a neAV school, and the then dominant school should have ban- ished a man Avho desired to shoAv them a neAV problem, is really difficult to divine. When we think hoAV little, from a practical point of view, Ave have advanced, and hoAV difficult is the progress of medicine, Ave should be more forbearing toward one another, at least for the sake of the human family. With a liberal spirit for the common cause, Ave should go forAvard in one arduous path, and Avork our Avay with the well-settled truths, that to heal the afflicted was one of the great missions of the Redeemer, and we should follow him Avithout questioning or gainsaying. It is our most solemn duty to accept truth and knoA\dedge, for they have been given by the Omnipotent himself to those whose under- standing has reached that degree, and Avicked indeed it unquestionably is to refuse to look, hear or be told. We are surely reaching another inquisitorial phase in our medical history, but, thank God, there are men strong enough on both sides to annihilate this assumed " non possumus " of late days. It is also unquestionably admitted that the toxic effects of medical agents Avere the first indications of their pathogeny upon the animal economy, and from that rough frameAA'ork our books on poisons Avere con- structed. These morbific outlines Avere of such great interest that from them greAV the study of the agents in smaller and safer quantities; by the varied and numerous in- teresting researches from all the civilized Avorld, their properties and effects upon the human system were ascertained. Inasmuch as the possibility of learning a great deal to our advantage in this field was demonstrated without a shadow of doubt, many a generous government estab- EFFECTS OF MEDICAL AGENTS. 285 lished institutions of public learning, free to all and at public expense, since the benefit Avas to be universal, (a true humanitarian idea) and thus botanical gardens and botanical chairs of learning Avere established, from Avhich our materia-medica originated, and Ave Avere thus able to arrange in some sort of scientific order, all the mixed and unintelligible gibberish of the old alchemists. It was from toxicology that Ave have received our first knoAvledge of the nature and morbid effects of certain agents upon the animal economy. And by the use of them in such quantities as Avould only produce temporary disturbances, Ave have ascertained their modus oper- andi as medical agents. This mode of procedure brought about further in- quiries, thus the physiological action of these agents Avas discovered, with perfect safety to the system. " Beck's Murray " says: " Medicines operate by exciting to action the general system, or the particular organs on Avhich they Avork. They have further than this no specific influence or properties, but are adapted to the removal of morbid affections, by producing excitement (partial or general) Avith certain degrees of rapidity and force. " When medicines are thus determined to particular parts, they are either directly conveyed, by being re- ceived into the blood, or their action is communicated indirectly from the stomach by the medium of the ner- vous system; and in both Avays important local effects are produced." But yet, these gentlemen have never demonstrated from Avhat principle these cures Avere expected or ob- tained, except by stimulating, urging, pushing and forc- ing nature to bring about her vis medicatricae-naturae, and thus overcome the morbid disorder that may be disturbing physical harmony of action. If stimulating the physical forces alone Avas sufficient, then the prob- lem Avould soon be solved. But Ave must have drugs 286 PROGRESSIVE MEDICINE. AAdiose specific action upon diseases may be ascertained by their pathogenetic similarity to any given disease, and thus they prove to be useful as therapeutic agents. " It Avould not be advisable to give opium Avhere quin- ine is indicated Avith any reasonable degree of common sense. No one Avould dream of administering camphor for capsicum or belladonna, although they are all nervo- stimulants; they Avould bring about excitement both physico-vital and physico-organic, but, perhaps not the desired effects. Again the physiological school say you must give a remedy that is fit or adapted by its knoAvn properties and effects to every specific disease. Hoav are Ave to know Avhether belladonna acts more specifi- cally upon the vaso-motor nerves than camphor? I an- swer, because it creates a rash and a congestion; it stimulates all the capillaries, etc.; but these are some of its pathogenetic effects, and Iioav are Ave to expect any- thing else than an increase of the disease if Ave give a medicine Avhich is knoAvn to produce similar mischief or disorders. 'Never mind that,' says the physiological school, 'do not give camphor, or quinia Avhere bella- donna is the remedy.' But poor Hahnemann, Avhen his bright genius saAv the plain and simple truth, and dared to say 'the action of all medicines is on the principle of similarity,' he Avas treated as Galileo Galilei, Avhen he dared say 'E pur si muove.' " But truth is as great noAV as then. The medicine whose pathogenetic effects or symptoms resemble more those of any given morbid affection (or natural disease), is truly a remedy of confidence and to be relied upon in neutralizing the morbid phenomena arising from natural causes. And I would further say, that to substantiate this truth, Ave need not Hahnemann's observations, but Ave have only to refer to Allopathic authorities Avho recog- nize the facts in their own Avay, but neglect to teach them as laAvs of similarit3% EFFECTS OF MEDICAL AGENTS. 287 Doctor EdAvard J. Waring says: "Almost every drug operates differently Avhen given in large and small doses. Tartar-emetic for example, in doses ofl-12th to l-16th of a grain acts as a diaphoretic and an expectorant; in doses of \ to £ of a grain as a nauseant; and if carried to the extent of tAvo or three grains it proves a poAverful emetic. A very similar series of effects is produced by graduated doses of ipecacuanha; recent observations, indeed, tend to sIioav that this drug in very small doses acts as a poAverful anti-emetic" " The neutral salts aperient in large doses, and diu- retic in small; opium as a stimulant in small doses, and a narcotic in large ones; and the oil of turpentine in doses of fl. drm. i. to fl. drm. ii. acts as an acrid irritant of the kidneys and genito-urinary organs, Avhilst in a dose of fl. oz. i., and especially combined Avith castor oil, it operates freely on the bowels Avithout producing any renal or vesical irritation. These are but feAv examples out of many Avhich might be quoted; but it may be ob- served, generally, that most of the medicinal substances whose operation is mild and beneficial in small doses, may be converted into poAverful poisons by being ad- ministered in large quantities." But AA'hy has not this able physician gone on Avith his subject and told his colleagues the rest of the grand dis- covery, Avhich I premise by saying that it Avas knowu and taught by Hahnemann? Why not tell them more of the principles of affinity, polarity and attraction of medical agents? of the atomic force and molecular at- traction? And this brings us face to face Avith the facts, that, a solution of a fluid is only a larger extension of its atoms. And that a disintegration of a solid from its cohesion is only a separation of its atoms. Matter, therefore, be it vegetable, metalloid or alkaline, is divisible into three forms: gaseous, fluid and solid; in all three, there is the same Aveight and number of atoms. 288 PROGRESSIVE MEDICINE. The only difference exists in the form or manner of division, i. e., solution, trituration, decoction, etc And in support of this theory Ave knoAv that the only differ- ence betAveen Avater and steam is that the latter is Avater SAvollen by heat to 1800° to one cubic inch. But this is not all; chemistry says " that from a simple and great principle of II. C. and 0. N. arises organized matter," yet other elements enter often, like sulphur and phosphorus, and perhaps many more unknoAvn to us. What is important to knoAv is not so much the change of materials or components as the change of shape and position of the molecules Avhich in reality change the nature and grand phenomena of organic matter, the illustrations of molecular structure thus far studied have been mostly taken from those classes of compounds long knoAvn in chemistry under the name of acids, bases, and salts, and they Avere selected because it was Avith such substances that the old theory had al- most exclusively to deal. But, as I haA-e already said, the strongest evidence in faA-or of the neAV theory is to be obtained from a class of substances about Avhich the old chemistry kneAV almost absolutely nothing. The class to Avhich I refer is formed of the compounds of the elementary substances and carbon. The number of of knoAvn compounds of this element is far greater than that of all the other elements together, and these ex- hibit a greater diversity of their molecular structure, which is often highly complex. As a rule they consist of a very few chemical ele- ments besides carbon, hydrogen, oxygen and nitrogen, but the number of atoms united in a single molecule may be very large, sometimes even exceeding 100. Carbon is peculiarly the element of the organic world, for, leaving out of view the great amount of Avater which living beings ahvays contain, organized material consists almost exclusively of carbonaceous compounds. . EFFECTS OF MEDICAL AGENTS. 289 Hence the substances, Avith exception of a feAv of the simplest, Avere formerly called organic compounds; but, although the cause Avhich determines the groAvth of or- ganized beings is still a perplexed question, Ave iioav know that the materials of Avhich they consist are sub- ject to the same laAvs as mineral matter, and the com- plexity may be traced to the peculiar qualities of carbon. But Avithin a feAv years Ave have succeeded in preparing artificially a very large number of Avhat Avere formerly supposed to be exclusively organic products, and not only this, but the processes Ave have discovered are of such general application that Ave iioav feel Ave have the same command of the synthesis (combinations) of organic as of mineral substances. The number of elements which enter into the com- position of organic compounds being so restricted, i. c, C. 0. H., it is evident that the immense variety of qual- ities Avhich they present cannot be referred solely to the influence of a simple radical C. 0.= Avhich they con- tain. In the simple compound C. Q.» there are the elements C. 0. H. N. bonded together, but the last two, i, e., II. N., neutralize each other. There are then compounds in all single medical agents, the radical being the basic substance, Avhich is represented by quantivalence, and its variation changes the nature and the effect of the element in use. The folloAving is an example: from ammonia gas can be derived a large class of compounds, in all Avhich nitrogen is trivalent. And similar preparations can also be made Avith phos- phorus. But although they all contain the same atoms as a nucleus, the tAvo classes differ from each other as Avidely as if they Avere composed of different elements. " Returning noAV to our comparison," says Professor J. P. Cooke, "betAveen H. 0. N. and H. 0. N. 0.* Ave 290 PROGRESSIVE MEDICINE. shall describe the relation of the molecules in a feAv words by saying that the acid and the alkali had mole- cules of the same general structure, but differed in that the radical of the alkali Avas the elementary atom (po- tassium), while the radical of the acid was the atomic group, N. O.2 "And again, first butyric acid is an oily liquid Avith whose smell Ave are only too familiar, since, Avhen formed in rancid butter it imparts to this article of our food its peculiarly offensive odor. Further, as its name denotes, it has the qualities of an acid." Utterly different from this offensive acid is the second substance, which Ave call acetic ether, a very limpid liquid, with a pleasant fruity smell, highly volatile; yet butyric acid and acetic ether, have exactly the same composition and the same vrapor density. ANALYSIS OF ISOMERIC COMPOUNDS. f BY GRUNZWIEO, ) (BY LIEBIG, ) \ Butyric acid. J \ Acetic ether, j Carbon, 54—51 Carbon, 51—47 Hydrogen, 9—26 Hydrogen, 9—67 Oxygen, 36—23 Oxygen, 35—86 And this Avill add strength to our subject, Avhich is that in order to change matter organic or inorganic it is only necessary to have a change of molecular arrange- ments. From a nourishing, healthful butter, Ave haAre it changed into a poisonous, acrid acid; and that true science has found that molecular movement and division give force and activity to matter. It is not shoAvn that artificial medical compounds can add, but on the con- trary they often detract from the object in vieAV. All simple products are nevertheless compound elements, but then activity depends upon the radical product, be it sulphur, or tannic acid, or ammonia, atropine, caffein, EFFECTS OF MEDICAL AGENTS. 291 the active principle will be the predominating force radical in the product itself. Thus simple remedies, well knoAvn and Avell sub- divided so as to separate their molecular activities, are a correct principle based upon a chemico-medical ground. To return to our study: Ave know the effect of a cer- tain medicinal dose. The quantity, then, determines the effects toxic, pathogenetic, stimulant (or physiologic), dynamic. The first Ave have nothing to do Avith. The other effects are sufficiently knoAvn to justify the classi- fication. But Avhy call this a hypnotic, that an alterative, the other an emetic or nervine, etc, Avhen Ave knoAv that such cannot be stated, except with only partial truth. Opium is both hypnotic or soporific and stimulant. In coma produced by general physical disorder opium is almost a specific In coma from renal troubles opium is also a great agent. Why? Because opium's pathogenetic effects shoAv its sphere of action, e. g., brain, kidneys and cir- culation. When those organs are similarly affected by disease, opium releases them (in small doses) from the morbid influences. We never forget, hoAvever, to potentize it, thus developing its molecular activity. Having stated these facts in the first part of my work, I only apply them noAV in support of the medi- cinal and dual action of medical agents. In conclusion, it is an undeniable fact, that Avhen a large dose of any medical substance is capable of pro- ducing morbid symptoms, Avith similar symptoms (from natural causes) a small quantity of the same agent is sure to bring about a reaction, thus neutraliz- ing the morbid phenomena. This is called the law of similarity. Although in diseases of the gastro-enteric juices the question Avill be met more on a chemico- physiological ground. 292 PROGRESSIVE MEDICINE. Unquestionably the quantity necessary to produce certain effects has been and Avill ahvays be a specula- tive, open question, according to idiosyncrasies and temperaments; but the curative principle must invari- ably be that of similarity, notAvithstanding. This is an infallible rule, and the true beacon-light in the right direction. And it is undeniable that Similia can only succeed in her claims by shoAving practically that Avhat has been stated is correct beyond question. Doses must naturally differ, for the very nature of the medical agents themselves demands a difference. Let us take quinia, for example, the king of antiperi- odics, yet not ahvays successful. One to five grains is the dose ghTen by the dominant school. I shall find no fault with them, for I use it myself in nearly the same quantity. It all depends upon the severity of the sym- toms. And this very agent in large quantities produces, according to Doctors Waring and Pareira, cinchonism. They say " Within the first tAvo hours xii grains of quinia produces a marked excitement Avith tension and throbbing head-ache, morbid sensibility of the eyes to light, buzzing and ringing of the ears, vertigo, unsteadi- ness of gait, and some excitement of the heart, a sense of internal agitation and general excitement; the face is flushed, the skin is warmer, and the pulse and respi- ration are more frequent, and massive doses are often folloAved by delirium. " Again the reaction sets in and aphonia ensues, the heart and pulse become feeble, and the temperature of the body falls. "Finally, a prolonged use of quinia may cause a dimi- nution of the red globules, and an increase in the pro- portion of fibrine and Avater in the blood (Leuco- phemia)." Noav, then, very little more Avould give us the Avhole outlines of the regular malarial intermittent fever • and EFFECTS OF MEDICAL AGENTS. 293 just here Ave must stop and reflect that such symtoms, such pathological analogy betAveen chills and fever and the pathogenesis of quinia is a striking illustration of the truth of what has been asserted. At the same time some sceptical reader may say that all this is very well and sounds right, but where are your infinitesimal doses ? Once for all, I reply, infinitesimal quantities was a Hahnemannian idea, which he connected Avith therapeutics, but has nothing to do Avith the laAv, Avhich he only folloAved by logical deduction from facts, indis- putable then as iioav. While it cannot be admitted that infinitessimal doses Of medicines are at all connected Avith the laAv of thera- peutics of Similia, nevertheless it is true that by our neAV process of division of molecular activity, a much less quantity of medicine is required and better results are constantly obtained, and it is perfectly proper that all physicians should study Iioav to cure Avith the least quantity of medicine, and not Iioav much they can give with impunity, forgetting the danger of re-action, fre- quent failures, and the Avant of science connected thereAvith. Thus one-tenth and five grains of quinia are perfectly compatible Avith the above-stated law, because the medi- cine is not a rank poison, and it requires considerable to produce any pathogenetic disturbances, and because in malarial diseases Ave have a malarial poison Avhich requires a sufficiency of the medical agent in neutral- izing its morbific influences. Although smaller doses do often ansAver as Avell in the common simple in- termittents. My rule is to use 1-dec of a grain and to increase it gradually to one and five. The same may be said of ipecacuanha. In large doses it produces either vomiting or evacuation of the intestines, together Avith a gastro-enteric irritation. It produces irritation of the nares, larynx and 294 PROGRESSIVE MEDICINE. bronchi. It affects the nervous system and has proved a good anti-periodic at times. The dominant school uses it pretty much as the neAV school, except that with a thorough study of its pathogenetic effects the neAV school prescribes with more knoAvledge and better success. Subdivision is a mode, as Ave have already demonstrated, to separate molecular matter and to bring eATery molecule in connection Avith the part extended to be treated. Phosphorus and ammonia are two remedies frequently used in phthisis, pneumonia and bronco-pneumonia. Who can deny the effects of these tAvo agents upon the air passages ? What pharmaceutical preparations are better adapted to each case is left to the general intelli- gence of the physician. There are many preparations of ammonia, namely, carbonate, chloride, acetate, etc. Phosphorus, likeAvise—phosph. of ammonia, calcarea phosph., kali phosph., etc These agents have been lately introduced in different forms: phosphites and sulphites of soda, ammonia, phosphites of magnesia and soda, or substances in which potassium is the base. These are great blood elements and Avould soon disorganize the blood, producing anaemia and phosphate diseases. In small doses they have been found by Professor Polli to be great remedies for all diseases arising from a foment; Ave must not forget that in such conditions they act as chemico-dynamics, because, although in large doses they may disorganize the blood, they could never pro- duce a zymotic disease, but the effects and results would be similar. Astonishing as it may seem, the parallelism betAveen alkaloid substances and acids is chemically true, as it is chemico-physiological. The therapeutic uses of the acids taught by the learned Dr. Prout to his OAvn school and colleagues, were knoAvn to the practitioners of the new school and EFFECTS OF MEDICAL AGENTS. 295 used by them before they Avere even thought of except as chemical re-agents. Indeed, it is a fact of great therapeutical value that Avhere the phosphates of soda, ammonia, lime and potassa are indicated as dynamic remedies (or physico-dynamic), that phosphorus, or phosphoric acid, nitric, sulphuric, hydro-chloric and ace- tic acids are also indicated. The analysis of isomeric compounds opens our eyes to these facts, namely, that in a medical sense the base being either sulphur, nitrate of potash, phosphorus or ammonia, these Avould be three acthae substances in forming disease, and thus de- termining their action. The prolonged uses of acids, mineral and vegetable, produce morbid influences Avell known, of physical or- ganic disorganization, and although they differ in prox- imate principles, they are nevertheless strongly related by their ultimate elementary products. Their pathogeny differs as to intensity, locality and affinities. They are chemico-physiological agents of great importance in therapia. " Sulphuric acid is a frequent refrigerant, cooling and diminishing the temperature of the body through its astringency upon the capillaries. It improves the tone of the taxed mucous membranes and stops excess of evaporization and extravasation of blood (or purpurea hemorrhagica). It acts upon the liver and kidneys like all acids, promoting oxidation and ejestion. It adds force to the gastric juice, leaving to it its oxygen. These symptoms, seemingly so very desirable, are soon changed (by a stronger preparation of the agent) into pathogenetic symptoms, i. e., ulceration of the throat, mouth, larynx, tharynx and stomach. If con- tinued, gastro-cnteritis Avould soon take place, and in ad- dition the solids of the body Avould become affected, neutralizing the supply of lime from the blood. Our second agent, hydro-chloric acid, acts more upon the gastric juice and liver. But this very useful sub 296 PROGRESSIVE MEDICINE. stance would produce disarrangement of the same or- gans Avhen in a healthy condition. Nitric acid is a poAverful escharotic and is mostly used in malignant ulcers, in diphtheria and in gangrene. It is useful in syphilis, in glandular enlargements and tur- gescence. It is given to promote absorption, and im- prove cachexia. It is used in all those cases Avhere kali-iod., iodine, chlorine and lime are used, and even creosote. It is unnecessary to describe every acid and its peculiar pathogenetic effects, for the profession is well aAvare of their therapeutic influence. In small doses they a.re indicated in all those patho- logical conditions \vhich Avould be liable, in large and continued doses, to be produced and therefore their pathogeny and similarity of symptoms in disease, are the tAvo main indications of their medicinal agency. In typhoid fever, sIoav remittent fever, diarrhoea, hemat- emises, eruptive fevers, in phthisis, trachealis, in apep- sia, in glucosuria, in gastric fever, etc. Their effects by pathogenetic doses cannot be denied to resemble Ioav specific diseases and to be excellent remedies Avhen prescribed on their OAvn indications and symptoms. Classifications like heamatica, corrigentia, stimulantia, tonica, seclantia, narcotica, antacida antiseptica, etc., etc., are empty expressions Avhich are of great injury to the student, because Avhen he learns these by heart he thinks he has all the materia medica and therapeutics at his finger's ends. It "will be seen by every good phys- ician that eA'ery drug ought to be studied not only from its toxic, but also its pathogenetic, physiological, gen- eral, and special effects, its organic and systematic affinities, and then compared in diseases both general and special. By such a scale of comparative patholog- ical studies of both natural and drug disease, surely the resemblance betAA'een the natural and the artificial symptoms "will be striking and unmistakable indications for the selection of the remedy. EFFECTS OF MEDICAL AGENTS. 297 No fair minded student of the science of medicine can fail to see the strong analogy and natural logic of such an axiom. Practical common sense is the leading feature of the huv of similarity. Veratrum viride is called by the dominant school the king of sedatives, similar to aconite, tartar-emetic, anti- mony, etc Noav such a Avord as sedatiAre has not a signifi- cation corresponding Avith physiological uses and effects. But they say Avhat Avould Ave think of an agent that diminishes the pulse and the heart's action and capil- lary congestion? What Avould Ave say of a stimulant Avhich Avould have the same result in the course of a few hours? IIoav is hysteria or spasmodic action con- trolled by brandy, ammonia, capsicum, strychia, nux, ignatia, etc We ansAver that the name of sedative in a medicinal dose is a misnomer; the result of the medicine is named, not the agency from Avhich that result Avas obtained. Veratrum, aconite, tartar-emetic, opium and stramonium are stimulants (in small medicinal doses) and from that the excited circulation, the bounding heart, the throb- bing head are quieted through the effect of a stimulat- ing influence upon an excited condition of the vaso- motor and cerebro-spinal nerves. The result is sedative, through an influence and agency of an active medicine, thus neutralizing the tremor and hyperesthesia of the nerves and blood vessels. Just so the influence of stimulants Avill tranquilize Avhen hypersensibility and excitability exist, if such doses are used as accord Avith the strength and nature of the remedy and the indi- A'idual. Dr. Waring does not give an explanation of the ac- tion of veratrum, in varying doses, but only in the abstract, as a sedative of great power, namely, a depres- sant Avhicli diminishes the arterial circulation. And as parallelism is not mal-a-propos, I beg the liberty to compare Dr. W. II. Burt's " Characteristic 298 PROGRESSIVE MEDICINE. Materia-medica on Veratrum," and Dr. Waring's action of the drug; thus Ave get a good idea of Avho is the best authority and most reliable Avriter. Dr. Burt says, " Veratrum viride selects for its centre of action the cerebro-spinal system, bringing its greatest force to bear upon the pneumogastric nerve and by paralyzing its functions produces congestion and inflam- mation in every organ and tissue to Avhich it is distrib- uted. This action can be better explained by saying that the vessels become engorged with blood by lacking that propelling nervous force Avhich the agent has thus paralyzed, and hence central, or cerebral, pneumonic or cardiac stasis. " Diseases that call for these remedies must have their starting point in the cerebro-spinal nerves." The pathological changes Avhich veratrum viride is capable of producing are due to the microscopical re- searches rendered by Dr. Adams. This microscopical examination of the brain revealed intense capillary con- gestion. " The convulsive centre is located in a limited space on the floor of the fourth ventricle in the pons-varolii." We found great capillary congestion of the pons, and this solves the problem why veratrum \Tiride is so valuable in spasms of a congestive nature. In puerperal convul- sions that have for their origin some emotional cause and Avhen there is some excessive cerebro-hyperaemia, veratrum viride is, of all remedies, the first to be thought of. The Doctor says further, " aconite, although acting on the same organs and tissues, spends most of its force on the spinal filaments of the vaso-motor nerves of the capillary blood vessels, so as to produce congestion in every tissue in the body that contains capillaries (such are the parallelisms of the two greatest agents of the materia-medica) Avhile veratrum only affects the great centre of circulation." EFFECTS OF MEDICAL AGENTS. 299 Still another interesting comparative analogy exists between veratrum A'iride and belladonna, and although similar in their sphere of action, yet the pathogenetic disturbances and influences are totally opposite, and the result may be looked for Avith considerable confi- dence. Veratrum viride prostrates organic functions and circulation, in its morbid action (sensible doses) by its paralyzing effects; belladonna on the contrary pro- duces the same morbid phenomena by an entirely differ- ent train of symptoms, namely, by its stimulating and exciting cerebral congestion. The explanation can easily be arrived at Avithout great difficulty, and is as folloAvs: Veratrum produces inflammation and extravasation, through the sudden paralyzing influence of its toxic effect, and cuts off the vitality from Avhich the vessels receive acthnty and motion, namely the nervous force, thus producing almost apoplexy. Belladonna produces an inflammation, turgescence, and congestion, by exciting nervous force, thus causing hyperaemia of the blood vessels. As Ave do not accept anything but facts, Ave are not troubled with delusions. The way to employ these three remedies is clear and logical, namely, by the general and specific laAV of similarity upon the organs Avhose functions are morbidly affected. Their duality of action primary and secondary, the first pathogenetic, the second therapeutic, will accord with the different pathological lesions and symptoms belonging to each agent and disease. If Ave have cerebral congestion and great nervous tension, resulting from traumatic reflex action, together with a tonic spasmodic contraction of the muscles from Avhich circulation and nervous reciprocal action are wanting veratrum in small doses is the remedy. But in congestion from an over-excitement of the nervous centre or sympathetic system of nerves, belladonna Avould be the remedy. 300 PROGRESSIVE MEDICINE. So the dual action of medicines is a Avell established fact. The only true Avay to find their right employment is to study their pathogenetic influences, and the morbid symptoms of the natural disease. In puerperal fever, in trismus, in cardiac paralysis, in cerebro-spinal meningetis, in pneumonic hypostatic dis- eases, veratrum Avould release the equilibrium of cen- tral circulation by its influence upon the cerebro-spinal plexus, i. e., the pneumogastric nerves. Belladonna acts more upon the sympathetic and A'aso-motor nerves when circulation is disordered by excitement. Glonoine, like \Teratrum, will release a decided neurotic congestion which proceeds from nervous tension and spasmodic irritability. Aconite-glonoine, A'eratrum viride are analogous, just as opium, belladonna, stramonium and hyosciamus are similar. Carbolic and Salicylic Acids.—Both these substances originate from carboniferous sources, and their isomeric chemical compounds are strikingly suggestive as to their relation in a therapeutical sense. Their haAdng de- cidedly beneficial medical effects is iioav unquestioned. One is extracted from coal tar, the other from charred AvilloAV Avood. Such carboniferous substances are of a pungent escharotic nature, depressant, exciting, stimula- ting and irritating, affecting the Avhole general system, and having decided effects upon organic functions and physical and dynamic forces. They are found in the blood, and affect the absorbents very greatly. The nervous system becomes also sensibly affected from centre to periphery. They affect the brain, the organs of respiration, the kidneys, the gastro-enteric fluids, and the nervouu sys- tem, Avith a great muscular relaxation, besides aphonia joined Avith considerable irritation and excoriation of the larynx, tharynx, trachia, stomach and bowels. Such are the well knoAvn generalities of the morbid effects of these elements upon the animal economy. EFFECTS OF MEDICAL AGENTS. 301 Hahnemann in his experiments calls the attention of the profession to the modus operandi of carbo-vege- tabilis, Avhich, although used by the old school as an anti- acid, and in dyspepsia, is otherAvise not used except as a disinfectant in cases of putrefying Avounds or tumors. But our old observer Avent to the trouble of testing the drug, and found it an antiperiodic and antiseptic and an anti-zymotic It induced cardialgia> great de- pression of the organs of generation, paleness, inter- mittent pulse and Avant of proper oxidation. And if these prominent symptoms mean anything, I presume they mean a general disorder of the co-ordination of organic functions and physico-vital phenomena. The symptoms are those of a sIoav but steady retrogressive change in the general process of organization and phy- siological activity. The blood and nervous system become decidedly devitalized and anaemic. This devi- talizing element suggested the idea that in zymotic or fomenting blood diseases it would stop the disintegra- tion and the retrograde metamorphosis of physical Or" ganization. When an effluvial or alluvial poison has produced typhus or typhoid fever Which have a tendency to de- stroy the organizing principles of life, i. e., the blood, the nervous system, the gastro-enteric juices, and finally, all that is organic in functions and repair, become as it Avere, changed from the remotest nucleus to the protein- aceous compound. The plastic formations of the blood become impossible, and hence, loss of corpuscles, in- crease of fibrine and Water. The saline principles Avhich form the viscid, gummy fluid thus holding to- gether the elementary principles of plastic matter, pass off the body unassimilated, and hence the Avhole fabric falls to pieces for AVant of building material. In these cases and in chronic diarrhoeas, ulcerations, diphtheria, etc. our carbon vegetalis or mineralis are agents of un- questionable affinity and force of action. 302 PROGRESSIVE MEDICINE. Medicine to-day stands exactly like new and old chemistry; related, and yet distinctly simplified; changed Avhile the basis and the elements in use are still the same. And Avithout going into a dissertation of a chemico- physiological nature, I should unhesitatingly pronounce these tAvo remedies as the most promising elementary substances in the treatment of zymotic disease, be it scarlatina, measles, diphtheria, croup, infectious or con- tagious diseases like cholera, yelloAv fever or malarial and insidious cerebral feA*ers, pernicious and congestive inflammations, either cerebral, pneumonic, abdominal or laryngeal. The pathological effects of carboniferous, exhalation, in various degrees Avill coArer a ground Avith A\'hich Ave can easily compare the pathological conditions and symptoms of all the above diseases. The pathogeny of these remedies is the guiding star, the quality of their action exists in tangible doses pro- ducing diseases similar to those that have been de- scribed and in dynamic doses, destroying them Avhen present. The tAvo elements differ in intensity of action and therefore must be given in different doses. But I should not hesitate to recommend salicylic acid from one-tenth to five grains, carbolic from three-tenths to one-tenth only (internally). And I feel that if I have not convinced all my col- leagues of both schools of the truth of duality on the prin- cipal of similarity, I nevertheless have opened a fair field for dispassionate and scientific discussion upon the broad basis, Similia similibus curantur. The great truth of the duality of action of medical agents, could be even better and more practically illus- trated by the primary and secondary action of alcohol. Every one knoAvs the exhilarating sensation of a drink of champagne; many remember the sensation of EFFECTS OF MEDICAL AGENTS. 303 suffocation, burning heat in the throat and stomach and cerebral excitement of the first dose of strong wines or spirits. It excites the pulse, it quickens the imagina- tion and renders every capillary subject to receive an extra amount of blood from the great centre. And these temporary amenities groAV in a degree ac- cording to the use or abuse of the agent. Hilarity is Avell knoAvn to Till and there is a greater degree called over-excitement. From these degrees Ave go on further into the field of excess and intoxication. From a simple exciter, in large doses it becomes narcotic; it benumbs the muscular activity, it decreases organic functions, and the heart becomes sIoav and Aveak in activity, and full of venous blood. The circulation is thus disturbed, the brain becomes as if narcotized, loses its force, and is in a turmoil of disordered co-ordination; hence stupidity, or vague and foolish hallucinations, etc. The nervous system becomes feeble and trembling, and hyperaesthesia sets in,Avhich is demonstrated by Avant of mental poAver, apepsia, agitation, fear, excitement and unreasonableness. The hair becomes white, the nutrition is abnormal and evanescent, having no real stamina, either physical or vital. And if continued it results in (delirium tremens), imbecility, and general adynaemia. In this short sketch Ave have, in a general sense, the primary and secondary action of alcohol. And from these outlines Ave can easily select our agent for the diseases in Avhich it is therapeutically indicated. We cannot question its great usefulness in certain diseases either sthenic or asthenic, acute or chronic It produces (in sufficient doses, and continually used) those very morbid conditions varying in degree and character, according to the idiosyncrasies of the patient. General Stimulants.—They exalt the sensibility of the nervous system, the action of the muscular fibre, as well as that of the mucous membrane. They augment the 304 PROGRESSIVE MEDICINE. strength and frequency of the heart's pulsations, give vigor to the play of the lungs, and raise the tempera- ture of the Avhole body (primary action). Modus oper- andi : " Amongst the most important, if not the most important, of the actions of alcohol, in a therapeutic point of vieAV, is the influence Avhich is produced on the circulating system. That the administration of alcohol increases the poAver of the heart, diminishes the fre- quency of its beat, and augments the force of its con- traction, under conditions of its debility, are facts Avhich must be familiar to all who are in the habit of prescribing it. And there is nothing more striking and more satis- factory than to Avatch the effects of the remedy in those cases of asthenic inflammation Avhich are marked by a rapid and Aveak pulse. Under its use Ave see a pulse, abnormally quick, gradually fall ; Ave see an irregular one become steady and regular; Ave see delirium sub- side* and tongue, foul, dry or broAvn, assume a moist and healthy character."—- Waring. Far as I am from considering any school of medicine perfect, or consistent in all things, yet this is too great a discrepancy from the antiphlogistic treatment used and propounded by the Broussanian-school of France. And it is so glaring a departure from old theories that even Dr. Waring says " Within the last five and tAventy years a great change has taken place in the vieAvs of the majority of medical practitioners in this country on the subject of stimulants in the treatment of acute diseases." And Avith this testimony, undeniable as it is, I cannot find any practical explanation of the therapeutic mode of action of alcohol. But I believe that facts cannot be denied by one even prejudiced against a school, such as a stimulant is to be used in inflammatory diseases, in sthenic diseases and in nervous affections. Now on AAdiat principle can such a remedy act, except that of similarity in lesser or EFFECTS OF MEDICAL AGENTS. 305 greater degree? In examining the diseases of alcohol- ism, Ave find doubtless all the phases from its beginning to its end^from mere excitement, hyperaemia cerebralis, to violence and congestion of the brain. From simple hilarity to agitation and convulsive movement doAvn to prostration, asthenia and typhoid condition. It is not for Avant of candor that many of the great thinkers do not speak, but I believe they hold their peace from fear of offending their colleagues. The truth of the action of these remedies is too strong to believe that it has escaped the attention and notice of the able authorities of the old dogma. I should not do full justice to the Allopathic profes- sion, if I should not give them credit for this great dis- covery. But at the same time I must premise, that, physicians of the new school fully recognize the import- ance existing in the proper use of alcohol in diseases. And, it Avould also add much if Ave had a distinct line marked out Avhen and Iioav to use these remedies. Tweedies says: " 1. It sometimes happens that when a patient in fever has been progressing favorably, the pulse becomes suddenly soft and compressible, the skin cool and damp accompanied by a feeling of considerable exhaustion; Avith these symptoms, there need be little hesitation in alloAving six or eight ounces of Avine in •twenty-four hours, at proper intervals. 2. When the symptoms denoting sensorial disturbance, languor, Ioav muttering delirium, tremor subsultus, are progressively increasing, and if at the same time the patient lose his strength from day to day, the pulse becomes soft and skin cool. 3. Alcohol should be used Avhen the fever assumes the petechial character (typhoid, putrid, mala- rial, remittent, intermittent, continued). 4. And also in cases of sudden collapse, some Avith stertorous breath- ing, melancholy, mania, Avith inclination to murder— delirium, hallucinations." 306 PROGRESSIVE MEDICINE. I should also add pneumonia, second stage of scarlet fever, small-pox and diphtheria. In chronic diarrhoeas, and in suppurating wounds, etc. Alcohol as a Remedy and as a Nutritious Substance.— It especially arrests destructive mal-assimilations, so that for a certain period, during the stay of alcohol in the system, less urea, less phosphates, less water are ex- creted by the kidneys; less carbonic acid by the lungs, and less digestion goes on in the alimentary canal. " But at the same time, they give rise in the body to defensive re-action Avhich is prominent first, and then gives place to the special action." So that if a suitable quantity be taken, and both ac- tion and re-action are alloAved to exhaust themselves before the dose be repeated, there will be a positive gain in vitality, " but if such a large quantity be taken that the re-action is overpoAvered (or the forces dimin- ished) the body is not reneAved, because its effete parti- cles are not removed."—Burt. APPENDIX. 307 APPENDIX. NUTRITIVE CONSTITUENTS AND ALIMENTATION. The nutritive constituents of the numerous articles of diet, their nature, proportions and agencies in the great process of alimentation, is obviously a study in Avhich every medical man is interested, and with which he should be Avell acquainted, thus facilitating the selec- tion of articles containing those properties Avhich the physician considers necessary to supply the deficiencies existing in the economy during a condition of transitory physical abnormalities. At the very first Ave can see the difficulties in forming a correct diagnosis as to Avhat is needed by the idiosyncrasis of the patients constitu- tion, and the difficulty in selecting the materials Avhich contain the true elements that are required by the economy Avhen in a condition which is considered out of equilibrium. Without this knoAvledge, our profes- sion Avould be a sad failure indeed, in her very first principles of restoration. I need not dwell long on this subject to persuade the profession of its usefulness; in diseases, as a restorative principle—in health, as a preventative of disease. Mechanical, chemical, dynamic, or physical forces, depend 308 PROGRESSIVE MEDICINE. for their equilibrium upon the elements of nutrition, the manner of preparing them, the best articles of supply, and when, where and how to use them. To this there are to be added other considerations which are indispensable; such as climate, seasons, idiosyncrasies, sex, age, occupation, temperament, etc. In thermal countries certain diet is admissible, Avhereas, in cooler and extreme northern latitudes the opposite, in the nature of the ailments, Avould be re- quired. Food is the anchor of life, and Avithout it no hope, of physical development can be secured; therefore it is an absolute, unconditional necessity, and superlatively needed as a restorative principle. In disease, there- fore, it is of the greatest importance to knoAv Avhat the physical economy has lost, and what it requires; and to seek for the articles which contain the necessary con- stituent to re-establish the lost physical equilibrium, or to hold it in its normal condition where no descend- ing vital signs have taken place. In describing the proximate constituents of the nutri- tive elements Ave must observe; 1. The functions of Avater; 2. Of albuminoid compounds; 3. Carboniferous substances; 4. Amylaceous (starch); 5. Glucose (gum and sugar); 6. Mineral salts; and 7. Nitrogenous ele- ments. The proteinaceous compound, fibrin, albumen and gelatin, is changed and animalized in the stomach, into fibro-peptones, albumino-peptones, gelatino-peptones; these compounds are thus metamorphosed by the pro- cess of digestion through a secretion of the follicles of the stomach, being the true animal dia-stase juice, which organizes the nitrogenous elements and separates them from the starchy cellulose elements, just as the dia-stase by the enteric juice separates the starchy materials APPENDIX. 309 from the albuminous fat's, gluten and glucose (carbonif- erous) compounds. QUANTITY OF ALIMENT THAT WILL YIELD 1220 GRAINS OP NITROGENOUS MATTER. NUTRITIVE EQUIVALENTS IN A DRY STATE.--PER 1000. Skim cheese, lb. 1-4 nitr. 1220 ANIMAL VEGETABLE Lean meat, " 9 oun< White fish, "1.0 " Fat meat, "1.3 " " ..331 . 81 Bread, "2.1 " " Beef........ ..880 . 84 Rice, "2.8 " " ..305 .100 New milk, "4.2 " " H. milk..... ..100 Rye.......... 10(5 Potatoes, " 8.3 " " ..237 Wheat....... .119 Turnips, "15.9 •' Yolk of egg. Eel......... Mutton..... ..305 434 ..773 125 138 White Bread.. .142 ..833 Black Bread... .166 910 239 ..914 271 ..756 .283 Pork..."..... 893 320 Veal........ ..873 These tables show that red herring and ham in a dry state yield nine times more nutritious material than the dry matter of human milk, yet these do not shoAv that all such elements can be appropriated, assimilated and utilized as products for the greatest nutrition. Nitro- gen is not all that is required by the human economy; other materials equally important, if not more so, are to be considered. Here we Avill divide starch as vegetable carbonaceous from animal fat carbonaceous, the latter being much richer in carbon—2.s greater than sugar. It appears that an adult requires 1.267 grains of car- bon, Avhich is to be obtained from amyloids, glucose and fat animal food and 181 grains of nitrogen, to be ob- tained from albuminoids and meats or animal food. (Animal and vegetable nitrogenized food). 310 PROGRESSIVE MEDICINE. AVERAGE PER CENT. OF NUTRITIVE ELEMENTS OF ANIMAL AND VEGETABLE FOOD. Bread.'....... Beef......... Fat Beef..... Mutton...... Fat Mutton... Wheat Flour. Barley Meal.. Oat Meal..... Rye Meal.... Indian Meal.. Rice......... Peas......... Arrowroot.... Potatoes...... Veal......... Pork........ Butter....... Beer......... Yolk of Egg.. White of Egg Skim Milk... 8.1 19.3 14.8 18.3 12.4 10.8 6.3 12.6 8.0 11.1 6.0 23.0 2.1 16.5 9.8 47.4 66.3 69.6 58.4 69.5 64.7 79.1 55.4 82.0 18.8 3.6 3.C 4.9 5.4 3.7 0.4 0.4 2.0 2.3 5.1 4.4 4.8 3.5 2.3 2.0 3.0 1.8 1.7 3.5 2.5 3.2 0.1 16.0 24.4 4.0 87.0 30.7 5.4 1.0 0.7 4.7 2.3 2.0 0.2 1.3 1.6 0.8 as starch, 55.0 animal fat, 9.0 animal fat, 71.50 animal fat, 12.25 animal fat, 77.75 as starch, 75.50 as starch, 80.30 as starch, 77.80 as starch, 78.20 as starch, 85.35 as starch, 81.25 as starch, 62.65 as starch, 82.00 as starch, 22.50 animal fat, 39.50 animal fat, 122.25 animal fat, 207.50 as starch, 8.70 animal fat, 76.75 animal fat, 9.90 APPENDIX. 311 AVERAGE PER CENT. OF NUTRITIVE ELEMENTS OF ANIMAL and vegetable food.—Continued. w < W S P w P ■Si S < o p oa P 03 P 0Q P. w a o « Skim Cheese...... 44 68 74 66 74 15 4.8 13.2 21.0 2.7 18.9 8.8 6.3 16.4 3.8 26.7 4.1 73.3 4.9 2.4 1.2 1.8 3.0 2.9 animal fat, 15.75 animal fat, 41.00 animal fat, 9.50 animal fat, 69.55 10.25 183.25 24.8 Tripe.............. 13.2 21.0 2.8 2.7 Ox Liver........... 18 9 Dried Bacon........ 8 8 It is clearly shoAvn that the amyloids, sugar and gum amount to 70.05 per cent, and the fat 2.0, so that the carboniferous vegetable matter (as starch) is to the nitrogenous as 7 to 1; and it is calculated that from two pounds to two-and-a-half is the average amount of food required by an active adult. Idleness does not re- quire but one and one half pound per day. It is obvious that the quality of the food has a great deal to do Avith the amount of nutrition received. Two pounds of bread Avill give sufficient carbon and nitrogen for the maintenance of life, but by using it alone health Avould be impaired. Cream is rich in butter, yielding 13 oz. to 15 oz. of commercial butter; it contains 34 per cent, of solid mat- ter, 26.7 of Avhich is butter; specific gravity 1.013. Meats differ very much in nutritive value according to the proportion of fat or lean: it is a common belief that beef is the strongest kind of meat; but the lean of all meats have nearly the same nutritive effect, provided it agrees Avith the idiosyncrasis of the digestive organs. Some cannot eat one kind of meat, but eat another with 312 PROGRESSIVE MEDICINE. perfect impunity. There is a difference betAveen fat and lean meats; the former contain more solid (carbon- aceous) in place of Avater, while the latter has only 28 or 29 per cent, of solid. The table on vegetable and animal nutritive elements shoAv exactly Avhich are the richest articles of diet, and from it Ave can select with sufficient accuracy the qual- ity of food most desirable for our purpose. And Avhen, from our diagnosis, Ave can decide what our patients are in need of, we can soon refer to our table for the selection of the elements of nutrition most suitable to their Avants. ALIMENTATION IN DISEASE. In acute inflammatory diseases, the febrile state in- duces serious changes in the constituents of solids and liquids. The interstitial fat disappears from the tissues, which become soft and watery. The muscles become flabby and pale, and lose their contractive energy. Digestion is feeble or suspended, the red corpuscles di- minish in number, and fibrinous plethora is soon engorg- ing capillary circulation. The blood suffers material alterations; the red corpuscles diminish, the fibrin in- crease and a pathological tissue metamorphosis takes place. The phenomena of the organism is that of descending to disorganization, and thus pathological products croAvd the intertices of the tissue, and there- fore the result is Avaste and struggle for eliminations of the poisons and decayed tissue changes. It is the in- tention of our efforts by a thorough knowledge of thera- peutics to prevent the occurrence of changes in the structure or parts of organs, and to favor the natural solution of the pathological process going on in the economy, and at the same time to repair the general lesions in the organism, which the occurrence of morbid action has induced. APPENDIX. 313 In this effort alimentation of a suitable kind becomes of the highest importance. Noav, then, the object is to supply the patient Avith those nutritiATe substances that he requires in his abnormal condition. What Avould be the proper alimentation in acute fevers or inflamma- tions ? We certainly cannot prescribe a carboniferous diet, neither a nitrogenous one entirely, for such nutri- ment Avould increase heat, circulation and carbonifica- tion. It is evident that Ave must use an amylaceous and glutinous diet. This compound Ave find in starch and albuminous nutrients. The articles that have these elements are rice, Avheat, flour, barley, rye and meal. These ingredients can be combined Avith animal food containing the least carbonaceous and nitrogenous ele- ments, and the greatest amount of gelatine, such as veal, lamb, chickens (poultry) and milk. In a broth made of lean veal, or chicken, and rice or barley, Ave have a com- pound suitable to conditions of inflammatory diseases. The Aveakest of vegetables—arroAvroot—Avhich has only starch, can be used also by combining it Avith rich milk. The functions of amylaceous, cellulose, and succulent substances called hydrates of carbon, are mostly calorific, yet they have a nutritious effect in their starch, gum and sugar. However, the animal fat is tAvice as great as that of starch (2.5). But these substances have other duties to perform beside caloric, Avhich is in fact the final result of their oxidation; for after starch becomes a glucose ingredient by physiological metamorphosis, it goes on further and takes the form of various acid com- pounds, as lactic acid, carbonic acid, butyric, lithic and uric acid, etc., which are found in the perspiration. Starch and sugar are also concerned in the production of fat. Farinaceous materials and sugar are very fat- tening articles of diet. And again, in cases of emaciation, provided it is not the result of organic and structural disease of the stomach, Ave can often develop some neAV plan of nutri- 314 PROGRESSIVE MEDICINE tion, based upon our knoAvledge of the various articles of diet, and succeed, if any success is attainable, by us- ing nutrients suitable to idiosyncrasis of the patient, thus increasing the adipose tissues. If the patient should digest well the animal fat, that Avould be more apt to increase the adipose tissue, being stronger than vegetable carbon. And for this purpose Ave should select Indian meal, peas, Avheat, flour, butter, milk, barley, rye, oat-meal and succulent vegetables like tomatoes, potatoes, fruits, etc., as articles of diet for those Avhose constitution is needing fat and histogenetics. But some albuminoids must be intenvoven Avith the carboniferous in order to proceed Avith the process of thorough reconstruction. Again, these articles of diet knoAvn as leguminous food, must be conjoint Avith the saline materials neces- sary to the economy, namely, phosphate of lime, sul- phate of potass, and phosphate of magnesia; Avith these, silicate and carbonate of lithicum are often present. From some other articles Ave get phosphoric acid,iron oxalates, etc., and oftentimes it Avould be Avell if we should select those nutritive elements containing cer- tain amounts of alkaloids, or salts, for these are the necessary elements for the plasticity of the liquor san- guini. " The saline constituents of food are largely concerned in the metamorphosis of matter; and, perhaps, this is the principal function, for it is a speciality for these substances to give a soluble form to the plastic consti- tuents of food and of the animal tissues. They are, therefore, concerned in the phenomena of digestion, ab- sorption, sanguinification, assimilation, disintegration, and secretion. In truth, they are the chief, if not the only, media for the transference of organic matter from place to place in the animal body, being, in one Avord, the purveyors of nutrient materials to the system, and also the carriers of effete substances out of it, besides APPENDIX. 315 Avhich, it is very probable that they are the agents whereby liquid colloidal forms of nutriment are changed into solids or pectous (vegetable basis of jell}7), as in the formation of solid tissues from the blood, and conversely, the solid into liquid." In the case of digestion and absorption, the plastic elements of our food, as albumen, fibrin, gelatin, etc., are not of themselves capable of dialysis by passing through the walls of the alimentary canal, and, therefore, absorption must be assisted by some physical agent. This agent is the highly diffusive acids and salts Avhich are secreted so freely into the stomach during diges- tion ; and they prove to be indispensable substances in the solution of the proteine compounds by converting or organizing them into peptones, changing the molecular form of the constituents, and causing it to pass from a thick, viscid, unabsorbable colloid juice into a highly diffusive fluid, thus facilitating dialysis by passing easily through the Avails of the alimentary canal. The colloidal fluid, after passing through the process of animalization, goes into the blood and assumes a crystalloid form, and therein Ave find the crystals of the alkalinity of blood, thus the molecular metamorphosis takes place from the fluid colloid into alkaline crystals. The phenomenon is rich in beauty, interest and use- fulness, and it is not ended here; the blood returns to the tissues, and there finding acids, it once more changes its molecular structure, and the crystals are diffused again for the purpose of nutrition. This does not exclude the process of the laAV of endosmosis and exosmosis, for those are physical functions of molecular affinity; the effects of the salts are to organize and facilitate ab- sorption and secretion, thus reconstructing solid tissue. In this way, step by step, the physical metamorphosis brings about a condition of pectous solid by the saline constituents, and according to their nature and propor- tion determine the degree of hardness. Again, an- 316 PROGRESSIVE MEDICINE. other physical and organic transition takes place, namely, the removal of effete materials and Avorn-out tissue. This is unquestionably affected by the agency of saline substances, for during the process of oxidation, acid compounds are produced in the shape of lactic, acetic, chloric, carbonic, phosphoric acids, Avhich,by act- ing chemically on the saline constituents of the animal fluids, give them a solutive poAver upon plastic matters, and thus enable them to remove the debris of worn-out tissue or superabundant secretions like bile, urea, car- bonic acidities of the enteric juices, etc. Of the special function of each of the many saline con- stituents of food so far, little has been demonstrated, yet it is a remarkable fact that the alkaline or basis, phosphate of soda is invariably found in the blood, while acid-phos- phate of potass is the chief constituent of the tissues. The alkalinity of the blood is a physical necessity in or- der to keep it in a colloidal form, and at the same time adding to its plastic metamorphosis. What is the agency of this phosphate of soda ? Tavo great pheno- mena and changes take place. It assists in the oxida- tion of organic matter, by absorbing and removing car- bonaceous products, changing them in the shape of phosphoric, carbonic acids. If this ingredient is not present in sufficient quantity, other carbonates perform that duty, and thus the effete matters of decayed tissues arc removed by the excretions. PER CENTAGE COMPOSITION OF MINERAL MATTER OF BLOOD. riips. ACID. ALKALINES. ALKALINE EARTHS. MINER. ACIDS AND OXIDE OF IKON. Pi< jjq <• APPENDIX. Time for Cooking. Mutton, five pound piece................. 1 < < qq Mutton, a large piece..................... 2 " CO " Lamb, a large piece...................... j << qq ,, Partridge, Pheasant, and Prairie Hen......30 to 45 m. PiSeon.................................. 0 lira. 30 m! Pork, four pound piece...................2 " 30 •' Turkey, a large one...................... ! to 2 hrs. Veal, a large piece.......................2 hrs. 00 m. Venison, a large piece.................... 1 << qq >> Of course, much depends upon the stove and heat. Soups.—These are fluid nutrients Avhich are extracted from vegetable, animal and fish. Hence vegetable soup, or animal broth, or fish soup. At times they are mixed, i. c, (the vegetable and animal products) so as to get the beneficial aliments of both ; both being required. And Avhen delicately flavored, they are called " the vestibule of the banquet." Hippocrates said " these extracts were invented be- cause they suited the invalids and sick." But science has made them eA'en suitable to people in health, as they can be made so nutritious as to take the place of solid food. The Pot-au-feu of the French peasant, and the rich soup of the French soldier are the chief rations on Avhich they subsist. All cooks are also coimnced of the utility of strong soup. It is an economical ingredient of diet: in fact it is made of many remnants Avhich otherwise could not be used. All the Avaste fragments are thus utilized and made productive of nutrition. Liebig says : " The attractive substances of flesh Avhen added to food, do duty as true nutritive materials in the place of those substances which are otherAvise produced from albumen." They cannot, perhaps, supply the place of albumen and fibrin in the nourishment of tissues, but they can replace the secondary products of albumen, Avhich are concerned in the development of 344 PROGRESSIVE MEDICINE. force; and as they are at once absorbed in the circula- tion, requiring no efforts of digestion, they not only create force, but they also economise it. They are, therefore, among the most valuable constituents of food. What are these constituents? We knoAv of the phos- phates existing in the bones, of the gelatine Avhich in- deed is largely extracted b} boiling, and the carbonates. These constituents are unquestionably great elements in the composition of the blood, except gelatine, Avhich is a tissue-making element. The most nutritious of all soups is obtained from cut meats, soaked for an hour or so in an equal Aveight of cold Avater, and gradually raised to the boiling point. After simmering for about a quarter of an hour, it should be Avell pressed and strained from the insoluble muscular fibre. In this Avay it retains the Avhole of the soluble constituents of meat, amounting to about five per cent, of the meat used ; so that a pint of this liquor from a pound of meat contains just four-fifths of an ounce of meat extract. But if the boiling is continued for a long time, a little gelatine is dissolved, but the strength of the soup is not materially increased. Coarser, but still good and highly nutritious soup can be made from lean meat and bone; as the leg or shin of beef. The meat should be sliced in small pieces and the bone Avell crushed; then put the whole in cold Avater Avith salt added. It should be heated gradually to the boiling point. After taking off all the scum, vegetables should be added and it should gently simmer five or six hours. After standing a little time to settle, it should be carefully poured off and strained; and Avhen cold, the cake of fat Avhich forms upon the surface should be re- moved. In this manner about four or fi\Te quarts of APPENDIX. 345 strong soup may be made from a shin of beef, Aveighing six or seven pounds. This kind of liquor contains 600 grains of solid matter to the pint, and of this 39 are saline. Chicken-Soup.—Roast or bake an old chicken until it turns color, then put it in a soup-kettle Avith three pints of Avater and put on a sIoav fire; remove the scum, add a small onion, some spinach or lettuce, and salt; let it simmer for about three hours. Take out the chicken and the vegetables, skin off the fat, strain and use. This broth is excellent for dyspeptics, and easy of digestion. The chicken is served in a salad. Veal-Soup.—Procure two pounds of lean veal. Put the meat in a soup-kettle Avith tavo quarts of cold Avater and a little salt; set it on a good fire, and skin off the scum as soon as it gathers on the surface. When skimmed add a head of lettuce and celery Avith a little onion; simmer it for about three hours: strain and use. This, as Avell as chicken broth, is excellent for convales- cents. It may be made richer by adding a little beef. Vegetable Broth.—Scrape clean and slice three carrots and three turnips, some celery and a little onion and parsley; fry the Avhole Avith a little butter till it turns rather yelloAv; stir and fry the Avhole about six minutes. When fried, add garlic, salt, pepper, two cloves and a little nutmeg grated. Cover it Avith about three quarts of Avater. Keep it on a sIoav fire, take off the scum carefully, and then simmer it for about three hours; strain and use. We may add a feAv beans or rice, and even peas. Bisque of Lobster.—There fish soups are exceedingly nutritious, and agree Avith people that are nervous, ex- hausted and have lost digestive force. In acute dis- eases, in tvphoid fevers, in all kinds of malarious fever Avhere advnaemia and inanition are threatening the very foundation of the organism, these elements of nutrition are preferable to animal food. They impart the phos- 346 PROGRESSIVE MEDICINE. phates of sodium and lime and phosphoric acid. They are nitrogenous and contain little fat, no starch and no sugar; one part of salts, although some fish have, like salmon, 5-5 of fat. The statistics show that the Avhite variety of fish give eighteen of nitrogen and seventy- eight of water. Saline and fatty materials 4. 0. per cent. It is indeed highly nutritious, and by the aid of culinary science, can be made in soup consomme, sup- plying the elements of force Avithout an oppressive load, thus requiring little digestive force. In these soups often times it is advisable to add some of the shell Avell powdered Avith the soft part; this is found to add a savor and render it more active upon the blood through its alkalies and phosphates. The Homeopathic physicians speak highly of sepia as a medicine Avhich promotes an activity in the portal cir- culation and lymphatics, particularly upon nervous ansemic Avomen. It acts upon the absorbents and secre- tions, causing irritability of the mucous membranes, constipation and ovarian plethora or excitability. No doubt that sepia stimulates the organs of generation. The virtue of the drug lies in its phosphate of lime and magnesia. These may have traces of silicon, chloride of sodium, etc.; and these constituents are Avell-knoAvn to exist in all shell-fish. The consomme of fish is pref- erable for invalids. Bisque of Lobster.—This famous dish is made by boil- ing one or several lobsters; after they are cooked re- move the meat from the claAvs and keep the flesh of the claws and tail for a salad. The head, stomach, and black Arein are throAvri aAvav, but the rest is kept and pounded together in a mortar Avith some shell. All small claAvs, shell, green, Avhite, or yelloAv matter, are pounded together. Then put a tablespoonful of butter in a sauce-pan, put it on the fire, and Avhen the butter is melted put in APPENDIX. 347 the contents of the mortar; stir it with a wooden spoon for about ten minutes, then add one pint of warm broth (or the water in Avhich the lobster Avas first boiled), stir it about twenty minutes, and strain. Put the liquor back on the fire, add about four ounces of toasted bread, boil it five minutes and mash it through a colander. Put the liquid on the fire once more, add one quart of broth or the water in which the lobster Avas boiled, boil it gently for ten minutes and turn it into a soup-dish. While it is boiling, pulverize a piece of the coral (col- ored shell), mix it Avith a little butter and press it through a fine sieve and put it in the soup-dish Avith crusty pieces of bread. When there is no coral in the lobster, mash up a hard boiled egg Avith butter in its place. With the addition of an egg and a little butter, the beef broth can be dis- pensed Avith, although the soup is not so rich, but is more fit for coiiA'alescents. Clam Soup.—This is a very delicious and nutritious liquor. Boil the clams in Avater half an hour. Take them out and use the flesh as folloAvs: Chop up the clams fine, put them in a sauce-pan Avith butter, salt, and pepper, and let them boil for half an hour, adding broth so as to make a rich gravy. Then take the Avater which Avas left, put it (pot-au-feu) over the fire in a kettle, put rice in it as soon as it boils, and cook the rice to the proper softness, then add your clam-broth mashed through a colander. It is a savory, pleasant and nutritious soup. But to improve its nutri- tion Ave may add half beef broth and half its oavti water. Julienne Soup.—Scrape tAvo carrots and tAvo turnips and cut them in pieces; put them in a sauce-pan Avith about two ounces of butter, three tablespoonsful of cab- bage chopped fine, and half an onion also cut up; set thfs on the fire and stir till about half-fried. • Add broth to make it as you wish—thin or thick. Boil gently till done, salt enough and pepper, skim off the fat and serve. 348 PROGRESSIVE MEDICINE. To this Ave can add tAvo ounces of boiled rice after hav- ing added the broth. Julienne aux Croutons.—Put some croutons in the soup dish, and Avhen the julienne is done, pour it over them and serve. Remember to cover the soup for five minutes so that the croutons may become tender and thoroughly steamed through. We may add barley or rice instead, or croutons, as it pleases the taste. Jardiniere Soup.—It is like the julienne soup, to Avhich is added the top or eatable part of a feAv asparagus, six turnips, red radishes, and two or three spoonsful of green peas. These are fried in butter and added to the boiling soup. SOUPS FOR THE SICK AND CONVALESCENTS. Consomme au Lait.—Milk may be used instead of broth when delicate digestion, the age and constitu- tion of the patient, or the idiosyncrasis of the disease demand it. Where the system requires a small amount of nutrition and repair, merely sufficient to keep up equilibrium, this preparation is Avell indicated. In acute diseases Avith plethora, like gout, rheumat- ism, scarlet fever, pneumonia, dysentery, gastric com- plications or bilio-enterio, troubles Avhere the chylifi- cation is difficult; in children of tender age, this pre- paration is particularly indicated. In Avomen after childbirth and dyspeptics generally ; after surgical operations Avhere a great quietude of circulation and of nervous action is required, it is useful to prevent any undue excitement. This is a good liquor to keep the patient upon for several days. With milk, use a little salt and sugar; it can be thick- ened Avith arroAvroot, corn-starch, and bread. Dry some slices of bread, either stale or fresh, in the oven, place them in the soup dish, pour boiling broth over them or milk, cover the dish and serve. Panade or Bread.—Take some stale bread, "-rate it APPENDIX. 349 fine, and then thicken Avith it a good generous chicken broth. Stir the bread for twenty minutes in the broth, add a little butter, and let it boil for half an hour, until the proper consistency is obtained. We often add tAvo yolks of eggs, beaten Avith tAvo tablespoonsful of cream; an excellent soup for infants. It is a soup of consider- able reputation in Italy for its nutrition and digestibility and simplicity, yet containing all the constituents neces- sary to an invalid or a child. Sago Soup.—Sago must be boiled gently about an hour, but it is prepared just like arroAvroot. Tapioca.—Is prepared like arroAvroot, and boiled about forty-five minutes. To these avc may add more strength by having some peas, beans, and lentils boiled in a little Avater, butter, salt and pepper; then mash them through a colander into the soup. Puree Soup of Lentils or Split Peas.—The proportions vary according to taste; the more peas that are used Avith a certain quantity of broth, the thicker the potage AvilPbe, and vice-versa. Soak one pint of peas in cold water over night and drain; put them in a sauce-pan with a feAv slices of carrots, some turnips, Avith a little onion and salt. Cover the vegetables Avith cold Avater, and boil them till done. Drain and then mash them through a colander. Return the liquid on the fire Avith sufficient broth to make the soup thick or thin, and season it Avith salt or pepper. Boil the soup for ten minutes, stirring in the meantime. Turn it into the soup dish, over croutons, and serve Avarm. Puree.—These are made of nitrogenous vegetables; they are boiled first in water, if dry, and then mashed through a colander into the soup to proper thickness. These delicate fluid foods, called soups, are the very best nutrients for the sick; from the variety given a selection is possible for a very large number of^ cases and variety of diseases. ?£RA?5 INDEX. Part I. Importance of Physiological Knowledge, Mai-Assimilation, Inanition, and Decay, Trousseau and Pedoux's Criticism, Predisposing causes to Mental Diseases, Part II Idiosyncrasies and Predisposition, . Proximate causes of Mai-Nutrition, Germinating Malarious Organisms, Physical and Mental Labor, . Diseases of Childhood, . Tabes Entero-Mesenterica, Eruptive Diseases, Scrofulo-Derma, etc Usefulness of Electricity, The dual effects of Medical Agents, Nutritive Constituents of Alimentation Alimentation in Disease, On certain Beverages, . Culinary Principles, Chapter I. II. " III. 15 28 51 Chapter I. 121 II. 134 " III. 148 " IV. 159 V. 210 " VI. 225 " VII. 254 " VIII. 280 " IX. 283 Appendix. 307 312 321 339 Si ^BFTJ'^V' NLM001391318