-— I— — — ____ | M =^= — h* n 1 ¦(V/\j£3t^v\. o i LECTURE f » , ON EPIDEMIC DISEASES GENERALLY, AND PARTICULARLY THE SPASMODIC CHOLERA. DELIVERED IN THE CITY OF NEW YORK, MARCH, 1832, AND REPEATED JUNE, 1332, AND IN ALBANY, JULY 4, 1832, AND IN NEW YORK, JUNE. 1833. .... WITH AN APPENDIX, CONTAINING SEVERAL TESTIMONIALS,— RULES OF THE GRAHAM BOARDING HOUSE, &c. BY SYLVESTER GRAHAM, PUBLIC LECTURER ON^^IfcNKE^OF HUMAN LIFE. oisono!is qualities, and consequently, less alarm will be given, and less jffort will be made to throw it off. By continuing the use of tobacco, and by slowly increasing its quantity, the peculiar susceptibilities of the nerves, which enabled them to detect its poisonous qualities, are more and more impaired, — till, finally, they not only cease entirely to give an alarm to the system, but on account of the injury thus done them, become so dependent on the stimulating properties of the tobacco, to raise them from the consequent prostration, that they even demand the continued use of the destructive poison, and with an imperativeness and pertinacity equal to the force of antipathies overcome in forming the demand. This constitutes the foundation and the power of the habit. But let it not be supposed that the tobacco is in itself less poisonous, nor that its effects on the system are really less pernicious ! True it does not produce so great an excitement of the nerves on which it immediately acts, nor cause so great an irritation of the organs generally; but this is owing to that impaired condition of the living tissues, which causes them to suffer equal or even greater injury from the less irritation ; and which renders them just so much the less able to resist the destructive action of other noxious agents, as they have been impaired by the tobacco. And this is true of the effects of all narcotic and alcoholic, and indeed, all other artificial stimulants, on the living tissues of the human body. It is an indubitable truth, that the action of all artificial stimulants, on the living tissues, is always, and necessarily, in the nature of things, at the expense of the vital energies of the tissues, and always impairs those natural and peculiar susceptibilities, which constitutionally adapt the tissues to their natural and appropriate stimuli. The necessary consequence of all this is, that throughout the human race, the vital power of the body to perform its organic functions, and maintain its victory over the causes which induce death, is reduced very far below the capabilities of the original constitution of man ; yes, very far below the present capabilities of the human constitution. Indeed, almost the entire human family make it a matter of continual practical experiment, to ascertain how near they can run to the line of death, and still maintain life ! Who but the suffering invalid — (and sel- 8 14 dom even he) seriously inquires, " What, and how much shall I eat and drink, and in what manner shall I live, in order to sustain my body in its healthiest and best condition ?" Does not almost every human being, rather, at least in practice, demand — How far can I indulge, and live 1 Is it surprising then, that we find the human race from generation to generation, leaning so far towards death, that their vital centre of gravity almost falls without the base of vital control ? And poising thus, is it a marvel, that even the moth and the caterpillar should often throw them from their balance, and send them headlong to destruction ? It'cannot, therefore, be any cause of wonder, that chronic and acute diseases, in all their dreadful forms and modes of destruction, should be multiplied throughout the human family, and sweep away the great majority of the species, even in the dawn of life ! Nor is it wonderful, that some local, or general cause, not powerful in itself, such as the exhalations of decaying vegetable or animal matter, the character and quality of food, a sudden change in the temperature, or humidity, or dryness of the atmosphere — or something else, equally simple and obvious in its nature and existence, should, in consequence of the peculiar condition of the human system, superinduce an endemic or epidemic disease, whose fatality "corresponds with the reduced state of the vital power of resistance in man, the influence of moral causes co-operating, and the propriety or impropriety of medical theory and treatment. In this manner, bilious intermittent, and remittent fevers, dysentery, typhus fever, yellow fever, scarlet fever, influenza, cholera morbus, &c. &c, obtain and become more or less general, according to circumstances and the nature of exciting causes. Cholera morbushas afflicted the human race, ever since the abusesofthe vital organs have been such as to induce that disease in the human body. The history of it comes to us from the days of Hippocrates, who flourished about four hundred years before Christ, — if indeed, we do not find a much earlier record of it in the writings of Moses. For there is reason to believe that the terrible disease which broke out so suddenly and raged so fatally among the Jews in the wilderness, at the time they ate so freely of the flesh of quails, was no other than cholera morbus. This disease is not in its nature at all times, if indeed it is ever necessarily of an epidemic character. In the time of Hippocrates, it was more commonly peculiar to the young and robust, who, by their occasional excesses, or improper diet, caused such an irritation of the stomach and intestines, and sympathetically of the liver, as to induce an increased, or, as it was called, a morbid or diseased flow of the bile into the alimentary canal, which produced violent vomiting and purging, in order to throw off the offending or irritating cause. The natural organic susceptibilities of the young and healthy are comparatively little impaired, and consequently they are more readily and powerfully disturbed by the presence of offending causes. When, therefore, any substance, decidedly offensive to the system, either from its nature, quantity, condition, or untimeliness, is received into the alimentary canal, the natural susceptibilities of which are healthy and vigorous, an instinctive alarm is given, which soon calls up the appropriate efforts of the system to expel the offending substance. This must be done by vomiting and purging, and to produce these, instinctively, an increased 15 quantity of more than ordinarily acrimonious quality of bile, is introduced into the stomach and intestines ; and this is effected by peculiar irritations of the liver, and these irritations depend on certain conditions of the stomach and intestines. In this view of the subject, which is purely physiological, cholera morbus seems to be the constitutional means, by which the system in* stincti veiy expels offensive and disturbing substances from the alimentary canal, and under such circumstances, the disorder, though violent, is far from being alarming, unless the disturbing cause is intrinsically and fatally poisonous : — tor with proper treatment, such as the free administration of warm water, to cleanse and soothe the stomach and intestines, — and often without any thing more than the unassisted efforts of instinct itself, the disturbing cause is soon removed, and the disorder ceases. But when a long train of abuses has greatly impaired, and perhaps almost, or entirely destroyed the healthful susceptibilities of the nervous tissue of the alimentary canal, and exceedingly diminished the vital energies of the system, if an irritation is induced which brings on cholera morbus, almost every thing concurs to increase the danger of a fatal result. For a morbid irritation once fully induced, in such a system, will not subside even when the first exciting cause is removed ; but feeds and increases itself by its own action. The same morbid irritability throughout the whole system causes the functions of all the organs to be more easily disturbed, and even arrested by the irritation of the stomach and intestines ; while on the other hand, the system has less power to sustain itself under these irritations, and to umaintain its victory over the causes which induce death. From such a condition of the human system it is, that the fatality of cholera morbus generally arises : — and such or nearly such, is the habitual condition of the bodies of a great portion of the human family ; in consequence of the almost incessant irritations that are kept up in the alimentary canal, by various causes in civic life ; but more especially, by the use of artificial stimulants, and particularly the narcotic and alcoholic of every form. As I have already observed, cholera morbus is a disease which has tn known for many centuries ; and in certain portions of the earth, it very extensively and almost uninterruptedly prevailed from the earliest periods of their history : and not unfrequently has it become epidemic and swept off immense numbers of the human family. The epidemic disease which is at present the cause of so much alarm throughout the world, and which has extended over so great a portion of the earth, and committed such dreadful ravages in its course, cutting off many millions of the human race, in the short period of a few years, though popularly called Cholera Morbus, Cholera Asphyxia, Spasmodic Cholera, &c, yet in its present form and character, the term cholera does not seem to be applied to it with strict propriety, as it is more remarkable for the entire absence, than for the presence of bile in the alimentary canal. lam inclined to believe, however, that this disease was originally, a proper cholera morbus ; and that from various causes operating through a considerable period of time, it has degenerated into its present character. And, in fact, it seems now in no important point to differ from that disease, excepting, that, instead of a morbid flow of 16 bile into the alimentary canal, there is a morbid flow or secretion of serotia fluid, which is even more acrid and irritating to the mucous membrane than the bile itself, and consequently causes more violent symptoms. Hence I suspect that the present popular name of the disease, was originally correct. The history of this terrible epidemic is too well known, to render it necessary or expedient that I should now enter into its details. Its march of desolation is rapid and fearful ! — We already contemplate its advances with dismay, and feel that its terrors are staring us in the face ! It concerns us now, to ascertain, if possible, its nature, its causes, its remedy and its prevention. In regard to the nature of this disease there has been rhuch speculation, and a great diversity of opinion. It is truly astonishing and even humbling to see how much the human mind is prone to throw obscurity and fearful mystery over objects which excite the sympathies and passions, and which are in reality far from being mysterious. It is possible that lam in an error on this subject ; but if I am not, there is much more plainness and simplicity about it, than is generally supposed. We have already seen, how the organic system, by its vital functions digests its food, and separates out, and more fully digests the chyle, and conveys it through the heart and pulmonary arteries into the lungs, where the process of digestion is. completed, and the nutrimental fluid received from the alimentary canal, is converted into living arterial blood. This blood, prepared for all the wants of the body, is returned to the heart through the pulmonary veins, and thence, through the arterial trunks and branches, and capillary extremities, is diffused over the whole system, and portions of it are detained and converted into bone, cartilage, muscle, nerve, and every other substance belonging to the body, while the remairring portion of it $nds its way, through exceedingly minute vessels, into the veins, in which it returns to the heart : while at the same time, all the different structures of the body, which are constantly receiving nourishment from the arterial blood, are also as continually giving off their worn-out particles, which, by a process of vital chemistry, are resolved into a limpid fluid, and this is taken up by a set of capillary vessels, called the lymphatics, and emptied into the veins and mingled with the returning blood. Thus, both by the absence of properties which are separated from the arterial blood, to supply the various wants of the system, and by the effete and refuse matter returned by the absorbents into the veins, the blood is deprived of its stimulating and nourishing qualities, and is brought back to the heart through the large venous trunks, dark, and full of impurities and wholly unfit for the uses of the system. If the blood, in this condition, should be thrown into the arterial circulation, it would immediately suspend sensation, voluntary motion and consciousness : ahd very soon, the nerves of organic life, wanting their natural and appropriate stimulus, would cease to afford their vital energy to the organs, — all the vital functions would be arrested, and life would be destroyed. To prevent this state of things, and to restore the blood to a condition suited to the wants of the system, the skin, the lungs, the kidneys, and perhaps some other organs, are continually, and should be vigorously employed in separating out and throwing off the impurities of the blood : 17 and the lungs and skin also digest a portion of tho atmosphere and incorporate it with the blood to increase its vital and healthfully stimulating properties. In this work of depuration, the skin ordinarily throws off, in the form of insensible perspiration, more of the impurities of the blood than all the other organs together. Indeed it is estimated, that more than half of all that is appropriated as nourishment to the system, ultimately passes off through the skin : and some eminent physiologists have asserted that more than half of all that is received into the stomach, passes from the body in this way. The power of these organs to perform their functions, as we have seen, is purely a vital power, depending on the state of the nerves of organic life ; and always corresponding in energy and vigor with the general condition of the digestive apparatus, and especially the stomach. When, therefore, the stomach is disordered and debilitated, and its function is feebly performed, the functions of the skin and lungs are less vigorous and complete, — the blood is riot so thoroughly purified, nor is so large a portion of the atmosphere digested and incorporated with it, to increase its living'energy and stimulating power. The whole organic system suffers in 'consequence ; the heart is less vigorous in its action, circulation is enfeebled, and the whole capillary system suffers a diminution of its vital power, on which all the processes of vital chemistry depend : and the body is consequently less able to endure cold and heat, £d is more liable to be injured by all the sudden changes of temperature, :t, conduct, and condition ; and by the action of noxious and pestilential uses. Let me again remind you however, that I do not intend to teach, that the stomach is the organ which generates and disseminates the vital energy of the neives of organic life ; nor that it is the centre of action to this system of nerves. In a healthy and normal slate of the human system, each organ has, probably, to a certain extent, its own more immediate and special centre of action ; and these special centres are associated by a more common centre of perception and action of organic life in the semilunar ganglions and solar plexus : while the top of the medulla oblongata, or head of the spinal marrow, is believed to constitute the general centre of perception and action to the whole united system of animal and organic life. The proper performance of the functions of life, and the welfare of each and every part of the system, depends upon the integrity of the nerves, in supplying the necessary vital energy ; and this again, depends on their healthy state, and the due subordination of every part, to its lawful centre of action. By inducing a diseased condition and inflammation of any part, a new and abnormal centre of action may be established, equal in the power and extent of its influence, to the importance of the part, and the degree of its morbid irritation ; which will not only derange the function of the part itself, but also to a greater or less extent, those of the other parts ; and sometimes, of the whole system : — causing an undue determination of the fluids to itself, and resulting in morbid secretion, imperfect assimilation, chronic inflammation and disorganization or change of structure, by softening or induration, producing schirrus, ossification, calculi, ulcers, cancers and dissolution : — or, mounting into a high state of acute in tlainmation, 18 and in a more violent and rapid career, bringing on gangrene, or general convulsions, collapse and death. Some of the functions of the body are, however, to a certain extent reciprocal ; so that the suppression of the one leads to an increase, and often to a morbid excess of the other. Such is the case with the functions of the skin and kidneys ; and also of the skin and lungs ; and perhaps some others in a small measure. Every person of any observation, must have noticed that copious perspiration, is ordinarily followed by diminished function of the kidneys: and that a suppression of insensible perspiration by chilly, damp weather, is generally attended with an increased function of the kidneys : and these excesses always correspond with the debility of the organs. But the welfare of the particular parts, as well as of the whole system requires, that each organ should uniformly and vigorously perform the full measure of its own duty, because frequent excesses arising from an undue determination of fluids to any one part, lead to debility of the part, and often result in impaired function, imperfect assimilation, local disease, and general injury and death. In this manner, sudden suppressions of the functions of the skin, often lead to diabetes or pulmonary consumption, by causing undue determinations to the kidneys and lungs, and inducing inflammation in one or the other of those organs, according as hereditary or self-originated predisposition renders the one or the other more liable to become diseased by such irritations. Besides these more natural reciprocities of function, it sometimes happens that a very diseased and violent reciprocity is attempted by the system. As for instance ; — when the function of the liver becomes deranged, the system sometimes attempts to force out the excess of bilious matter through the excretary organs of the skin ; and hence we have the manifestations of the disease, called jaundice : — and sometimes the liver is irritated and inflamed, and the character of the bile greatly affected by the excessive presence of those qualities in the blood, which should have been carried off through other organs. And again ; the system is liable to such a determination of the fluids to the mucous surface of the alimentary canal as excessively to irritate and inflame that very important membrane, and thus disturb and derange all the functions of life, and lead to the most painful and often the most fatal consequences. But this last disorder seldom, if ever, obtains unless irritation is first induced in the alimentary canal by the direct action of moral or physical causes, on its nervous tissue. Now, with these explanations before us, can the nature of the fearful Epidemic which is committing such ravages in the world, be regarded as in any degree a mystery ? Innumerable as are the irritating and debilitating causes which are continually disturbing and impairing the organic functions, and diminishing the vital power of resistance, can it be a matter either of mystery or surprise that a highly morbid irritability of the stomach and intestines, should obtain in a very large portion of the human race ? — All the organs must participate in the affections and conditions of the stomach. — The quality and quantity of the secretions are necessarily affected ; and every thing in the system is strongly predisposed to disease of any and every 19 kind. An adscitilious cause, which would scarcely affect, in any degree, • healthy system, may now be sufficient to induce the most violent and fatal disorder. In such a state of things, sudden atmospheric changes, or the presence of noxious gases or effluvia — togethei with exposures, fatigue,— exhaustion,— improper kinds, quantities or conditions of food,'— free use of heating and irritating condiments— fear— anger— venereal excess—and above all, excesses in alcoholic and narcotic substances, acting directly upon a morbidly susceptible and irritable stomach, and through it on the whole system, the utmost disorder must necessarily ensue. If the gastro-intestinal irritation be not of the highest order, the system endeavors to relievo itself from the irritating cause, by a mild form of ditorrhcoa, which, if properly treated, answers the instinctive purposes, and foon gives place to healthy action, and no further inconvenience follows — ut if thedrarrhoίa be neglected, and permitted to run on—and if irritatine rticles of diet be received into the alimentary canal,— and more especially, if heating and irritating astringents, tonics, stimulants, &c &c such as port wine, brandy, or alcohol in any form, or opium in any form, camphor, peppermint, ginger, mustard, pepper, &c. &c. be taken for the purpose of checking the diarrhoea, it is within the range of possibility that the experiment may succeed, so far at least, as to arrest, for a while, the disfeharges, and in some extremely rare instances the system may recoverbut almost inevitably the disorder will be aggravated ; and a highly morl bid, gastric, or gastro- intestinal irritation will be induced, affectin ff the «n nf 2 Ste a m f!\° rga(>iC "'T 8 ; and CaUsin S a P° werful determination of the fluids to the centre, and a copious flow of crude and very ex•sperattng serous fluid into the alimentary canal, for the morbidly instinctive purpose, of flooding away, as it were, the irritating cause. Violent UT if ""t rrTf^ fff ° r PV*™ instinctive P W P°^ ensue : attended generally, a first, w.th a high state of irritation and inflammatory action Jf the vascular system. The determination to the centreis still increased Insensible perspiration is suppressed.-respiration is labored and diffil\AA eX £7? CaP u aiy LL ° rganS are P rostrate d •• and the skin becomes cold and death-like ; while the messenteric, and other central vessels be come overcharged and generally highly inflamed. The liver, partaking of the distracting irritations, suffers spasmodic strictures of the gall-duct hnd thus its important secretions are shut out from the alimentary canal. .A,K V i GnergieS °t VV h ° nerves of or g«™ life are much impaired Iri WY t t I J 6 SyS , t6m ° f thGSe " erVeS be in a state of ex^««ve morbid irritability, the gastric or gastro-intestinal irritation will soon become overwhelming, and tne alimentary canal, in some or all its parts, immediately becomes an abnormal centre of action to the whole domain of orS JSTfL T^ 6nerv T energies, which in a normal state, radiate, as it were, from their natural centre or centres, to the heart, arteries vein* capiHanes, and all the other organs of the system, are almost "^^ enS fc£s^*"S TnlT n 1 P^^-toeir functions are scarcely plr- Ire wh 5 ' ° r , e " tireI J c u ease ' The fun ctions of the skin in particular, f, th?h°i y A n f a ' -{^ impUrities Which * should thro^ off, remain in the blood, to diminish its vitality and oppress the system. The blood vessels approach the same condition ;— the heart beats feebly, and perfcaps intermits ;-circulation is extremely languid j and the pulse scarce- 20 Iy perceptible. — respiration is exceedingly labored nnd difficult: th# calorific function necessarily ceases in the external parts, and the extremities and surface generally, become deadly cold 5 and the skin is often covered with a cold clammy moisture. The blood thickens, grows dark and sizy, and its vitality rapidly declines : while at the same time, all that can flow in the system, rushes, in horrid anarchy, to the centre, producing the most violent congestion in the vessels leading to, and in the vicinity of, the alimentary canal, causing an intense heat and high excitability of the parts, and inundating the stomach and intestines with a most excruciating serous fluid, which tortures beyond measure, the highly irritated and now keenly sensitive mucous membrane which lines them ; and thus exceedingly augments the suffering and increases the dreadful disorder. In such a state of things, can we wonder at the violent vomiting and purging I Can we be surprised at the intermission, or entire cessation of the pulse ; — at the complete suspension of the function of animal heat in the superficial organs, and the consequent coldness of the surface and extremities? Or can il be a matter of astonishmenVthat all the muscles of voluntaryand involuntary motion, supplied with nerves from the ganglionic system, brought, as they are, under a distracting and paramount influence, from thisncw centre of action, should be thrown into the most violent and painful spasms and convulsions? — Indeed ! can we wonder at any of the horrid manifestations of this terrible disease — this fearful anarchy of the organic powers — this tremendous vengeance of the injured, exasperated and frantic instinct ? For it is worthy of remark, that this dreadful epidemic appears to be peculiarly a disease of the organic domain. Animal life is seldom much affected by it, except through the medium of the ganglionic nerves ; and the brain, in particular, is seldom so much disturbed as to disorder the mental manifestations. A still more extreme case takes place in those who by excessive sensuality, filthiness and pernicious diet, have reduced the vital powers of their organic nerves almost to the line of death : an overwhelming gastrointestinal irritation arrests, at once, all their feeble functions of life ; inducing in a moment, as it were, a universal prostration, and almost instantaneous death, as with apoplexy or a sun-stroke. Great numbers of the canal diggers died in this terrible manner, at Georgetown, D. C, and elsewhere, in the summer of 1831, and in this same awful manner, the present epidemic has cut off thousands of wretched beings! In regard to the causes of this direful epidemic, I have already entered so fully into the consideration of them, that it is not necessary for me again to be very minute in their general detail. It may be said, in general terms, that the primary and paramount cause, is always, the peculiar condition of the human system, resulting from the violation of the laws of organic life. Its more immediately exciting causes, however, are various ; such as atmospheric changes and conditions — quality and quantity of food — excesses of e\ery kind : but more than all, perhaps, the excesses of filthy sensuality, and the use of artificial stimulants, and especially of the narcotic and alcoholic kinds; — in short, anything and everything that reduces the vital powers of the nerves of organic life ; and brings the alimentary canal and 21 with it the whole system, into a state of extreme, morbid irritability ; leaving little power in the system to sustain high irritation, and to resist and throw off noxious and disturbing causes. It may, however, with confidence be nsserted, that all the causes which obtain, beyond the control of man, would seldom or never develope this disease without the concurrence of those causes which operate through his voluntary conduct. But is there not some subtle agent, some pestilential essence, or some livingsubstance, — entirely distinct from, and independent of human agency, and above human control, — which passes from place to place, and by its own independent and absolute and malignant energy, induces this terrible disease wherever it exerts its influence ? I reply to this : in the first place, that the philosophy of the case requires no such cause ; and in the second place, that an accurate investigation of all the phenomena and facts in the case would never lead inductively to such a conclusion : and therefore, in the third place, that I cannot possibly yield my conviction to such an opinion. How then shall we account for the fact, that this disease is so extensively epidemic 1 That disease has swept over a great portion of the earth's surface with terrible devastations, is too fatally true to be denied : but what evidence is there of the essential identity, in all cases, as to the cause, of the disease, which under the name of Epidemic Cholera, has committed such fearful ravages in Asia and Europe ? Is it replied that all the manifestations and effects have been the same? But is this conclusive ? A fatal dose of arsenic introduced into the human stomach, will produce manifestations and effects, so entirely like those of malignant cholera morbus, that very few, if any, of the most skilful physicians, without some other information than that which they derive from the manifestations and effects, would, when cholera morbus was prevailing, hesitate a moment, to pronounce it that disease. A thousand other causes may, with the concurrence and co-operation of peculiar circumstances, develope the same symptoms, and cause the same results. Every pathologist ought to understand the nature of man thoroughly, in all its powers and properties : — not only organic and animal, but also mental and moral. He ought to be intimately acquainted with the physical and intellectual reciprocities ; the full range and power of sympathies, and all their physiological, and pathological, and psychological effects. In order to this, he ought to observe man in every attitude and condition, and under all circumstances and influences; and avail himself of every advantage and every species of information by which he can ascertain the truth. Much light might be thrown on pathological subjects, by a correct observation and analysis of the phenomena attending, what may, without irreverence, be called the moral and religious epidemics, which often become very extensive in society. Ido not name these things with disrespect, but merely for the purpose of exhibiting the effects of mental action on the bodily system. Time will not, however, at present, allow me to enter so far as might be interesting, and even instructing, into a minute detail of these effects on the functions and conditions of the stomach, liver, heart, lungs, skin, 1 22 brain, and other organs, and the pathological results which often obtain* I can only, at present, name some of the prominent results, which will serve to elucidate the subject before us : nor shall I pretend to chronological, nor geographical accuracy in the history of the facts which I mention : but I will endeavor to be correct in the facts themselves. About thirty years since, a powerful religious excitement commenced somewhere, I believe, in the State of Vermont. A fearful solemnity pervaded almost every mind. Deep and continued anxiety, arising from the exhibition and contemplation of awful subjects, and the feariul expectation of the presence and action of a mysterious agent, so affected the bodily organs and functions, that, in a moment of overwhelming excitement, an individual fell prostrate, as though suddenly struck dead by apoplexy. There was an ent/e suspension of animal life for some minutes. This necessarily increased the awful excitement of those who saw or heard of it. It was fully believed to be the effect of the immediate action of the Spirit of God, in renewing the soul ; and therefore, every one, with still more fearful anxiety, began to feel himself in the presence of the same mysterious agent, and that he was at every instant liable to become subject to the same action and the same effect. This again necessarily and very powerfully increased the predisposition of the body for such an effect. The result was, that another, and another, and another, fell in the same manner, and fully confirmed the belief, that it was a phenomenon connected with the mysterious operation of the Spirit of God in converting the soul. This led the subjects themselves to the full conviction that such a phenomenon was a demonstration of their genuine conversion ; and they awoke from their swoon, believing, and often shouting- aloud in the rapture of their belief, that they had become the inalienable heirs of eternal life and happiness. Of course, every tongue, with solemn tone, rehearsed the awful story. The excitement extended and increased, — and the phenomenon of falling down in a swoon, became truly epidemic. Preachers, and others, full of zeal, passed from place to place, and, with all the ardor of enthusiasm, and the untiring earnestness of those who desire to save the souls of their fellow creatures from eternal ruin, repeated and repeated the solemn story, with all the skill of circumstantial detail, and fervently, and often terrifically importuned their hearers to repent and believe, now, in the day of God's mighty power. The consequence, was, that sympathies wore aroused, — excitements were produced — and individuals began to fall prostrate, and wake from their swoons rejoicing and shouting ! — and in this manner this species of epidemic spread over a considerable portion of New England, and hundreds, if not thousands, were either " struck down " suddenly, or powerfully agitated, and nearly paralyzed in their bodily powers. - A similar excitement took place, several years since, I believe in Kentucky, in which the subjects were affected with powerful spasms in the muscles of the limbs — or sudden twitchings and jerkings in the arms and legs. This was also fully believed to be the effect of the immediate action of the Spirit of God in the work of conversion ; and consequently was regarded with fearful awe. Large circles were formed for prayer, and the anxious were brought within the circles — and united, and sometimes vehement and even boisterous prayer was offered, that the Holy Spirit would come down and convert them ; and these prayers were believed 23 to be answered by the Spirit's operations, when the H jerking" commenced, which soon took place, and generally extended to most of those within the ring. Some daring young men entered these circles with the spirit of derision — intending to practise an imposition on the religious ; but with horror, they soon found themselves, as they believed, under the irresistible influence of the Holy Spirit, and became powerfully affected with the involuntary spasms, and left the circle with the firm belief that they were converted. Such instances went still farther to confirm the popular belief that these "jerks," as they were called, were the effects of the direct and irresistible, though mysterious agency of the Holy Spirit. The consequence was, that they became extensively epidemic ; and those who were the most powerfully affected in this way, were considered the most signally favored, by the abundance of the power of the Holy Spirit. I might adduce several other instances of extensive religious excitements, which have been attended wiih different bodily phenomena, of as marked and peculiar character as any I have named. But I have already mentioned enough for my present purpose ; which is solely to show that certain actions of the mind may produce certain conditions of the nervous system, causing corresponding effects on the organs and functions of the body ; and that when peculiar causes have produced peculiar phenomena, and the causes are fully believed to be general, mysterious and irresistible, and the phenomena the necessary results of the action of those causes, the mind of all, coming under the same strong and continued excitement, may so act on the bodily sympathies, and through them, on the organs and tissues, as absolutely to induce the same involuntary phenomena in most or all ; and thus render them extensively epidemic ; while the very fact that they are extensively epidemic, will serve to establish more firmly the popular belief in an identical, mysterious, and irresistible agent. Now, if such is the philosophy, so far as bodily phenomena or symptoms are concerned, of moral and religious epidemics, why should we utterly disregard these things in pathological reasoning, and travel over the whole field of conjecture in order to find an adequate cause, when such a cause presents itself in the power of the sympathies directed by the actions of the mind ? Indeed we have the record of facts directly in point, to illustrate this doctrine in pathology. "It is well authenticated that females in the Royal Infirmary at Edinburgh, who were affected with hysteric fits, occasioned the same infirmity in others. It is well known, too, that in the poor house at Haerlem, in Holland, some years ago, a girl, under some impression of terror, fell into a convulsive disease, which extended on the mere principle of sympathy, to nearly all the boys and girls in the house. The celebrated Doctor Boerhaave put a stop to it, by preparing certain irons, and having them made red hot, in the presence of the children, and declaring, with great solemnity, that every child which manifested any symptoms of the disease, must be burnt to the bone with one of these hot irons. There was no occasion to use them, and the disease was no more known. — In the year 1803, a species of St. Vitus's dance became epidemic in one of the United States, on the same principle. Many more well authenticated instances of this kind might 24 be named, extending through parishes, villages, and districts of this country." But do you ask if I believe that such a cause can absolutely produce the Asiatic, spasmodic cholera I I reply, that I fully believe that, when long continued abuses have reduced the vital energies of the nerves of organic life to a very low level, in a great portion of the human family, extending over the face of the earth ; and tho human system is thereby strongly predisposed to take on disease, while it is little able to sustain it,— if certain local causes shall developo a disease pretty extensively, of a fatal and terrific character, the cause which I have named, is alone sufficient to keep up an epidemic disease, which shall be attended with most, or all the prominent symptoms of the first, and become as extensive as the quarry in which it originated. Moreover, such a cause, by long acting on those of better habits, may so irritate and debilitate the nerves of organic life, and so disturb the various functions of the system, as to bring on disorders, which will predispose the body to take on disease, and this, being improperly treated, may terminate either in the prevailing disease itself, or one which shall so assimilate itself, in all its symptoms, to the prevailing disease, that it will be unhesitatingly pronounced the same : and thus, epidemic disease may not only range over the level of its origin, but also frequently undermine, and sweep away many in the higher orders of habit and condition. In the winter of 1809-10, a disease broke out in New England, (I believe in Hartford, Connecticut,) which was very sudden in its attack, brief and violent in its career, and fatal in its effects. Much alarm was of course produced : every body talked about the new and terrible disease ; and every one was eager to hear the latest accounts of its progress and fatality. All the symptoms of the disease were carefully observed and published in the newspapers, and still more extensively by the ten thousand tongues of busy rumor, and listened to with deepest sensibility by the ten thousand ears of fearful anxiety. — The skill of the physicians was baffled ; profound and awful mystery enveloped the cause, and covered the mode and means of cure. The physicians, in the general panic and incertitude, abandoned the philosophy of physiological pathology, and gavo themselves up to conjectural speculation and excited imaginations ! — All was dreadful uncertainty, and fearful apprehension, and irresistible fatality. Death, shrouded in the impenetrable darkness of Egyptian midnight, walked forth with terrible omnipotence ! The dying bowed their heads and expired in unutterable agony ; and the living looked on with trembling consternation, and felt that they were contemplating the horrid imagery of their own unavoidable destiny ! Universal panic reigned with fearful despotism over the morbid sensibilities of society ; and every sympathetic pain and affection were apprehended with dismay, as an indubitable symptom of the fatal disease ! — Remedial experiments, corresponding in violence with the supposed power and malignity of the cause of the disease, were numerously tried ; and the work of death was more terrifically accelerated. Then, too, as in all other epidemics, ignorant quacks, with the well-meant concurrence of newspaper editors, spawned and promulgated their officious and mercenary prescriptions, to deceive the credulous, and bewilder the doubtful, and increase the excitement, and extend the devastation. — Medical men rashly published their violent 25 •Specifics, which bccnmo, in the hands of the terrified, like the weapons of death in the hands of the insane ! Hundreds, and probably thousands, felt the symptoms, and in the delirium of fear, poured down fatal quantities of brandy and laudanum, and plunged drunken and stupified into the forced embrace of death ! And thus the tremendous havoc swept on, spreading consternation before it, and leaving desolation behind ! — Legislatures adjourned, and fled in dismay — the affairs of society stagnated business was neglected, and men sat down in despondency and despair, to brood over their sympathies ; fearfully watching for symptoms, constantly taking preventives, and literally preparing their bodies for iln such a state of things,— and I have not given an exaggerated description—is it surprising that the epidemic Spotted Fever, or Cold .Plague, should extend over a considerable portion of New England, and sweep off hundreds or thousands in its career ?— And yet I have been assured by a highly respectable physician in Massachusetts, that after losing three patients with this disease, by the established mode of practice of the time, he abandoned that mode, and governed himself entirely by the indications of physiological pathology, and adapted his practice to the symptoms of the case, and never, after that, lost a single patient by §at disease, although his practice in it was uncommonly extensive. Inied, he assured me that the disease when properly treated, was more sily managed, than what is ordinarily called a bad cold. An epidemic disease bearing the same name, but less extensive and less fatal, because attended with less panic, and less error of treatment, has, for a considerable time past, prevailed in and about New London, Connecticut. There have been, I believe, several hundred cases ; the greater part of which have most unquestionably been purely sympathetic. tit is more than probable that an epidemic disease of any very great tent and mortality, never obtained among mankind, in which morbid sympathy and mental action did not constitute a very considerable portion of the efficiency of the epidemic cause. The history of all past epidemics corroborates this opinion : and we find that whenever and wherever the plague has prevailed, not a few even of the medical profession have believed that fear was chiefly concerned in propagating that terrible disease. Undoubtedly there have been at some periods in the history of the world, causes, connected with the disturbances of the earth, such as earthquakes, volcanic eruptions, &c. &c, and perhaps also with the influence of some of the heavenly bodies, which have produced extensive epidemic diseases fit have destroyed great numbers of the human species, and of the ver orders of animals. But these instances have, I am confident, en very few ; while as a general rule, as I have already said, it may th confidence be asserted that all the causes which obtain beyond the ntrol of man, would seldom or never develope epidemic disease, without the concurrence of those causes which operate through his voluntary conduct. And lam entirely confident that every symptom and effect, by which, what is called the Epidemic Cholera, is ordinarily attended, may be superinduced, in certain conditions of the human system, by mental action and remedial agents. Let me not be misunderstood : I do not say that mental action will absolutely induce spasmodic cholera, in any state of the body ; but, that 26 tn certain conditions of the body, mental action may so affect the nerves of organic life, as to cause that gastro-intestinal irritation, which is the basis of all the symptoms of spasmodic cholera : and that continued mental action of the same character, may reduce the body, from nny state of health, to that condition in which the disease may be superinduced. We know that overwhelming fear, by arresting at once, all the functions of life, may cause instantaneous death i and we know that violent and continued fear, may so affect the hair of the head, in a few hours, as to destroy its color : and that the same passion will suspend in an instant the functions of the skin and superficial capillaries, and impel the fluids from the surface to the centre, leaving the skin cold and corrugated, and cause a spasmodic, and irregular, and interrupted action of the heart and lungs, and induce pain and even severe cramp in the epigastric region ; and great irritation of the liver and kidneys, and sudden and violent evacuations of the bowek and bladder, attended often, with severe and painful spasms of the body and limbs ; and sometimes ending in sudden death* Unfortunately, however, in all times of great epidemical excitements, feat is not left to work single-handed in the mighty mischief, but leads to the use of such medical preventives and remedies, as are even more pernicious in their effects on the vital powers, than the passion itself; and thus the ruinous operation is earned on, while intemperance, and irregularities of every kind, come in as immediately exciting causes of disease, to consummate the dreadful work of death. To illustrate this doctrine still farther, let us take a single case in detail. Suppose an individual in good health, by continually hearing the accounts of the dreadful mortality, and terrible progress of the Cholera, to be filled with fearful anxiety in view of the probability that it will visit the place where he resides, and the possibility that he may fall a victim to it. He is constantly hearing fresh and shocking accounts of its ravages, and learns all its symptoms and horrors. The mystery of its cause, and the malignity of its career, increase his dread ! His thoughts frequently revert to the painful subject, and the suggestion arises in his mind, ?' I may fall by this awful disease !" — At length his mind comes to brood almost habitually on the alarming subject. His spirits necessarily become more or less depressed, digestion is disturbed, his appetite is impaired, the skin becomes relaxed and debilitated, its functions are less vigorous and complete, the circulation languishes : the lungs, the liver, the kidneys, and all the other organs, partake of the disturbance, and all their functions are correspondently impaired. Assimilation, secretion, and all the other vital processes, are deteriorated. All this reacts upon the stomach, and brain, and nervous system generally, to depress still farther the vital powers, and still more impair the functions : and these disorders of the body react upon the mind, to increase its despondency, and this again depresses still more, the functions of the body. And now the terrible accounts begin to produce great nervous agitation ; and this increases nervous debility and morbid irritability, which still farther enfeeble the vital powers of reaction against disturbing and noxious causes, and predispose the body to disease, and subject the individual to those frequent nervous and sympathetic pains and 27 affections which the fearful mind readily conceives to be the premonitory symptoms of the disease. Now if the unfortunate individual had knowledge and wisdom enough to regulate his conduct according to his peculiar state, he might, with utmost probability, still be saved from the evils which he so unhappily dreads. If he would carefully, in all respects, adopt a regimen suited to his peculiar condition and circumstances, he would be in little real danger of the disease. But alas ! how seldom is this course pursued ! With all their fears, and with all the disturbing and debilitating effects of their brooding anxieties and agitations, people generally pay little attention to their diet and habits of body, — as though their only danger were from some mysterious agent or principle in the atmosphere, or somewhere else, which absolutely and arbitrarily destroys life, without regard to habits or conditions of body. Or, if they do attempt to regulate their diet, the articles to which they will restrict themselves, and their modes of preparing them, are often even more pernicious than the things which they reject ; and thus the debility and irritability of the digestive organs are still more increased. And to relieve themselves from this depression, and languor, and despondency, resulting from the actions of their mind, and the conditions of their body, they will almost universally have recourse to strong tea and coffee, or to cordials or tonics, or fermented or distilled alcoholic liquors, or opiates, &c. — always, however, under the name of necessary preventives or medicines ! All these things necessarily prepare for the consummation ! Then comes the alarm-cry that the terrible epidemic has reached or broke out in the place, and begun its ruthless work of death ! The panic rises like a whirlwind I The morbid sensibilities, excited by the actions of the mind, are full of premonitory symptoms and affections : this causes powerful agitation, which almost necessarily brings on a disordered state of the stomach and bowels — more especially, if there is the least impropriety in diet ; and by this means the panic is tremendously increased. In this state of vital debility, agitation and terror, some of the vile prescriptions of the newspapers arc adopted, and the most pernicious, and often the most fatal articles, in the form of medicine, are thrown into the disordered and extremely irritable stomach. Perhaps, also, articles of diet of the most improper character are received into the alimentary canal : or it may be, that in this state of the system, some impure air — some noxious exhalation — some infectious effluvia, of a local nature or generation, acts on the highly morbid mucous membrane of the alimentary canal, so that by some or all of these causes, a violent irritation is produced in the alimentary canal, modified in its manifestations by the actions of the mind ; and a powerful determin ation of the fluids to the centre, and excessive central congestion, are caused by the gastro-intestinai irritation ; a crude and exacerbating serous fluid is poured into the alimentary canal, increasing exceedingly the irritation ; and then follow violent vomiting and purging, spasms, asphyxia, and all the other symptoms by which the case is ascertained to be spasmodic cholera ; and these symptoms are generally much aggravated by stimulating substances. The case which I have adduced, supposes a tolerably sound state of health in the nerves of organic life previous to the commencement of the 28 pnnio or fearful anxiety ; but throughout the whole of the human family, and especially in large cities and towns, a very considerable proportion of society is habitually in that low state of the vital energies, which requires little or none of the preparation for disease, that I have just described : their diet is sometimes — though in this country, unnecessarily, — scanty, seldom of the best kind, often of a very pernicious quality ; and their exposures are frequently great. Still, however, all these causes together, contribute much less to the actual developement of epidemic disease, than the universal, and generally excessive use of artificial stimulants ; in which the poorest and most wretched portions of society indulge. It is a well known fact, that immense numbers of the inhabitants of Europe and Asia, as well as of our own country, will voluntarily subsist on one or two scanty meals a day, of miserable food, for the sake ot procuring their ordinary quantity of tea, coffee, tobacco, opium, whiskey, arrack, or some other kind of intoxicating substance. Reckless as these unfortunate beings generally appear to be, yet, they nevertheless partake of the general panic ; which, unhappily, instead of restraining them from their habitual errors, more frequently, on the other hand, drives them to greater excess, as a refuge from the very calamity into which they are blindly precipitating themselves ! In such a state of things, fatal disease must necessarily be soon induced : and in such bodies, it must be malignant, violent, and brief; — and under such circumstances and influences, what would, at another time, have appeared only " sudden death," from drunkenness or excess, would now, almost necessarily, take on the type, and exhibit the symptoms, of the prevailing epidemic. Every such death will increase the panic, and consequently multiply the deaths, till excesses, and filth, and disease will, if other circumstances be favorable, generate a malignantly infectious effluvia, which will come in with the other causes, to carry on with tremendous energy, the terrible work of destruction. From this combination of causes, a pestilential efficiency is produced which those of healthier condition and better habits, and even the lower order of animals, will often fall before ! Thus the moral fens and morasses of society become the sources of pestilence and death, to those who have, perhaps culpably, neglected to improve their condition. It is upon this principle of mental action, affecting physiological conduct, and determining pathological affections and manifestations, that the notorious fact is to be accounted for, that during the prevalence of such an epidemic as the present, almost all other diseases assume the symptoms of, and run into, the prevailing disease : for this is seldom, if ever, the fact to any considerable extent, only during the prevalence of such epidemics as are attended with great panic. The epidemic Influenza is caused entirely by certain sudden changes in the atmosphere, acting on the human system in certain conditions, which result from the voluntary habits and customs of civic life : but this is attended with little or no panic, however extensive and fatal the disease ; nor during its prevalence, do any, except cognate diseases, take on its type. The same is true of all epidemic diseases of this predicament. On the whole, therefore, though I do not pretend, that panic, or mental 29 action, can absolutely and immediately produce real spasmodic cholera, in any and every condition of the human system, yet I do confidently assert that, taking into view tho va-ious causes which are continually operating on mankind, to reduce the vital powers of the nerves of organic life, and considering the actual condition of a large portion of the human family, as to vital power of organic function, nnd resistance to noxious and pestilential agents, mental action alone, is, through the modus operandi which I have described, an adequate cause for the epidemic character of the present prevailing disease, called spasmodic cholera, throughout the human race ! I Still, however, let it be remembered, that I do not say that this disease in every individual case preceded by panic, or induced by mental tion. I contend that highly malignant pestilential causes may be locally generated, and act on those who would not otherwise have had the disease, nor even with these causes, without a predisposition resulting generally, if not invariably, from their own voluntary conduct: and I contend also, that the pestilential cause or causes may be conveyed to, and fatally act, to some extent, in places where they would not have originated : and that they may be originated, in the manner I have described, in other places favorable for their generation, without the assistance of any imparted infection or medium of contagion. Treatment. The next question which comes to us, is — How shall we treat this dreadful disease ? — Here I confess, with a deep sense of the responsibility resting upon my undertaking, and of my want of knowledge of materia medica, that I feel fully conscious that I am passing from physiological and pathological premises, into the somewhat uncertain field of therapeutics. Perhaps it will be thought that I should stop short, nor ,presume to venture a speculative opinion on so momentous a subject. ; But since I have taken it upon me to speak, I will proceed : yet I will endeavor to be exceedingly cautious. What, then, shall we do with this disease, — especially when it assumes its severest and most fearful character? — When we find a prostration of nil the functions of life ; when the skin is totally paralyzed, the animal heat gone from the surface and extremities, the breath cold, the tongue dry, voice lost or very feeble, the heart scarcely heaving a sluggish, intermittent pulse, while violent vomiting and purging, and dreadful spasms, and burning pains in the epigastric region, and severe cramps in the limbs and extremities, seem terribly hastening the work of death, what shall be done? For surely, something must be done, and done quickly, or death will have achieved its victory ! I ask again, what is the immediate cause of all this derangement and >rostration ? Is it any external agent acting on the exterior surface, causing a paralysis and collapse of the superficial organs, and driving he fluids to the centre ? Certainly not ! — Is it any agent applying itself directly to the nervous system as a whole, and inducing general prostraion, collapse, and the other symptoms in the case ? By no means !—! — Vhat then shall we call it ? Most evidently and certainly, it is irritation n the alimentary canal, originated as I have described, and excited to madness by the acrid fluids which are pouring in from every quarter, and » 30 producing an excitement which distracts the normal distribution of net' vouB energy, from the natural centres to the several organs, and exerts a paramount influence over all the organs of the body, and blindly drags* all the vital energies into the vortex of its own maniac fury ! But what shall we do ? What does nature indicate by her conduct ? Does she not open the orifices of her alimentary canal, and with the agony of a blind and desperate Samson, heave, with all her remaining energies, to throw oft' the irritating and deranging cause from her smarting sensibilities ? She asks for assistance ! And does not the nature of the case, more than indicate the kind ? But it is said that we must rouse the prostrated functions ! We must produce heat, and circulation, and excite the action of the skin, and overcome the spasms, and arrest the vomiting and purging : and how can all this be done, without the exhibition of narcotics and stimulants % I say again, that nil the prostration and derangement is owing to gastric, or gastro-intestinal irritation, which has become an abnormal and maniac centre of action to the whole system of organic nerves, and all the organs depending on them for functional power ! Remove this irritation, and suffer the normal centres of action to throw their energies upon the organs, and the prostration and derangement are overcome, and the functions restored ! in such a state of things, will you exhibit your exasperating stimulants and deadly narcotics? And for what purpose? To shut up the floodgates through which nature is trying to relieve herself; and by your narcotics, to kill the excess of vital activity in the irritated organs, and by your fiery stimulants, to roll back the tide of ruin to other outlets, and force the heart and other organs to rouse from their prostration and perform their functions, under nil the embarrassments of distracting irritation in the gastro-intestinal centre ? But has not such practice been successful ? — Doubtless there have been instances in which such practice has been apparently if not really successful : — or in other words, some patients have recovered^ either with, or in spite of, this treatment. During the prevalence of all epidemics, and especially those which are attended with great panic, there nre always many spurious cases : and in these cases of purely panic, or sympathetic cholera, the exhibition of brandy and laudanum, (or some other powerful stimulants,) may sometimes seem to afford immediate relief; but even in such cases, always at the hazard of life. When these articles are administered however, in cases of real spasmodic cholera, if any benefit results, it is only in cases where the patient has previously been addicted to the free use of alcoholic liquors, and in the nervous tissue of whose alimentary canal, there is still remaining vital susceptibility and energy enough to receive and diffuso over the whole nervous domain, n stimulation sufficiently powerful to counteract the ruling despotism of the gastro-intestinal irritation, and force the organs into a performance of their functions, in spite of its bewildering and distracting influence. But if this species of forced action is not kept up by the continual administration of the stimulants, the patient must relapse « ith fearful rapidity, to the inevitably fatal action of the disease : and if it is kept up for any considerable time, iho idiopathic character of the 31 tisease may indeed be broken up, but it is always at the utmost risk f so wearing out the susceptibilities and energies of the system, that it r ill sink down into an equally fatal disease of a different type : or, if this should not be the case, and the patient should recover from the cholera by such treatment, he will continue, for a considerable time, to be subject to a serious derangement of the stomach and bowels, and will be exceedingly liable to another attack of the cholera, from the slightest exposure, or error of conduct. The cases however must be very few, in thich the least apparent benefit is derived from this mode of treatment : hile on the other hand, the most tremendously ruinous effects are proiced by such a practice. . How then, you ask again, shall we raise the system from its dreadful prostration, and overcome the spasms, and arrest the violent vomiting and purging ? Again I say, remove the irritation of the alimentary canal, and the spasms and vomiting and purging will cease; and the heart and the other organs will immediately recognize their allegiance to their normal Centres of action, and perform their functions without unnatural force. - But how shall we remove the gastro-intestinal irritation I—This1 — This depends much on the peculiar naturo of the case. Sometimes, as we have seen, the irritation depends entirely ou the presence of an irritating Substance in the alimentary canal ; such as improper articles of diet, $lc I and sometimes, from the peculiar condition of the system, and •specially, of the nervous tissue of the alimentary canal, the irritation, by whatever immediate cause induced, will propagate itself, and become a pathological affection of the tissue. I When the irritation is not overwhelming at first, the system instinctively ideavors to relieve herself, by pouring an increased quantity of mucous icretion into the alimentary canal, and thus relaxing and evacuating the nvels in order to remove the irritating cause : and if the stomach and testines are in a healthy and vigorous state, and the patient is careful abstain from every thing that would increase or keep up the irritation, c system will entirely relieve herself by her own instinctive efforts, and as soon as the irritating cause has been evacuated, the bowels will resume (heir healthy conduct. But when, from the previously debilitated and morbidly irritable state of the alimentary canal, the superinduced irritation becomes a pathological affection of its nervous tissue, the mucous secretion will run into a serous or watery character, and the relax will be followed by a diarrhoea, of a more or less mild or severe character, cor- IBsponding with the previous state of the system and the degree of morbid irritation. tlf the diarrhoea be of a mild character, and the previous habits of the lient have not been bad ; and if he keep quiet within doors, and totally d scrupulously refrain from every kind of medicine and aliment, solid *nd fluid, except a little simple Indian-meal gruel, or rice water, or coarse unbolted wheat meal gruel, or wheat bran tea, without any seasoning but a little salt, taking this at stated periods and in moderate quantities, so as not to interfere with the process of digestion ; and if the patient use a good deal of friction over the whole surface, and especially over the stomach and bowels, with a flesh-brush, or coarse towel, or flannel ; and be careful to keep clean in person, clothing, bed, house, &c> avoiding 32 confined, and impure, and damp, cold air, tho morbid irritation will be entirely subdued in the course of twenty-four hours ; and then, if the patient will subsist the next twenty-four hours on good, sweet, well-baked, coarse, stale bread, taking it at his regular meal times, and masticating it very fully, using no butter nor any thing else with it, and no other drink but his gruel or good soft water, at the end of the forty-eight hours he will find his bowels in a perfectly healthy state and action. But as surely as he takes any improper article of diet into his stomach, whether solid or fluid, while the diarrhoea is on him, he will increase the irritation, and aggravate the disease. Let it always be remembered, that the diarrhoea is not the disease, but the morbid irritation is the disease ; and the diarrhosa is the morbidly instinctive manner in which the system is endeavoring to remove the irritation ; and therefore an attempt to suppress the diarrhoea upon any other principle than by subduing the irritation, will almost inevitably increase the disorder. It is true that the morbid character of the serous fluid which is poured into the intestines, is a powerful cause of the irritation, and therefore it is highly desirable that the diarrhoea should be suppressed as soon as may be ; but still, I say, it must not be done by any means incompatible with the morbid irritation and irritability of the nervous tissue of the alimentary canal. Hence, brandy and laudanum, brandy and sugar, spirits of any kind, — wine, or fermented liquors of any sort, — camphor, peppermint, pepper, mustard, coffee, tea, and all other things of the kind, taken to stop the diarrhosa, are all, in their respective degrees, calculated to aggravate tho real disease, and bring on vomiting and spasms, and increased determination to the centre, and general prostration and collapse,or asphyxia and death! Itistrue that most of these things, may sometimes arrest the diarrhoea; but it is necessarily upon a principle which renders it almost certain that the disorder will soon return again with mci eased violence ; and more especially if any pestilential cause be acting upon tho system. It is also true that in some very rare instances, patients may recover with the us© of these articles : but the cases are only astonishing exceptions to correct rules : and the practice is none the less madly erroneous. In regard to the use of opium, to arrest the diarrhoea, or in any stage of the disease, I am convinced that it is little, if any less pernicious than alcohol. As a stimulant, it always increases the irritation ; and as a narcotic, in all cases, it reduces the morbid sensibility and irritation only by diminishing vitality ; and consequently, without removing in any degree the cause of that morbid sensibility and irritation; and therefore, when its narcotic properties are expended, the system is liable to more morbid excesses of sensibility and irritation, with less vital power to sustain them, and to react against morbific causes, and throw off" its own morbid affections ; and if it be repeated so as to keep the system under ks narcotic influence, it becomes itself a powerful cause of the rapid and total extinction of vitality ; and is thus very frequently made to supercede all other causes as an agent of destruction to the sick. For be it remembered, that it cannot possibly, in the nature of things, do any thing directly, towards restoring healthy action ; and healthy action alone can resist morbific causes, and give general health to the system. When the diarrhoea is of a more severe and violent character, and esr 33 pccially if it be attended with pain, and with spasmodic affections in the hands and feet; and, indeed, it will perhaps be safest to say, in all cases of diarrhoea, during the prevalence of the cholera, the patient should keep quiet within doors — or even take to his bed, maintaining as much composure of mind as possible, carefully abstaining from every stimulating and heating substance, take a gentle dose of rhubarb and calcined magnesia ; or, if his previous habits have been bad, and his stomach, liver, and bowels have been torpid, take a dose of rhubarb and calomel, or a free dose of calomel, and remain quiet upon his bed till the medicine operates, taking nothing into his stomach during the day, except the gruel, as I have before directed, and the next day the bread, or some other plainly ¦ and simply prepared farinaceous aliment, in solid form and freely masticated ; and continuing, for a few days at least, to be guarded and plain and simple in his diet, rubbing the skin freely, morning and evening, with a flesh-brush or coarse cloth, observing personal and domestic cleanliness, and avoiding confined and impure air, &c.,and no further inconvenience will be experienced, and health will be restored, unless there is some great imprudence. In cases where the diarrhoea has been neglected, or badly treated, till violent vomiting sets in with the purging, attended with spasms in the bo- I dy and limbs, cold skin, difficulty of breathing, &c, both cathartics and emetics will be unavailing, and they may serve to increase the irritation. In this state of the case, I should suppose that salt water, made as hot as the patient can endure it, and introduced freely into the stomach and intestines by potations and injections, would be the best internal application which could be made. My reasons are, that from some interesting experiments which have been made, salt is said to increase the fluidity of the blood when it has a tendency to thicken and coagulate ; and heat, we know, acts as a powerful stimulant on the living nerves without impairing ¦ their vital properties like alcoholic and narcotic substances ; while the water is calculated, at the same time, to cleanse the mucous membrane from its acrid humors, and act as a diluent and sedative. If, however, it should be found necessary in any case to use other stimulants internally, I should suppose that red pepper would be the safest and best, because it is more permanent in its action, than alcoholic stimulants, while perhaps there is no other stimulant which so little impairs the vital properties of the tissues on which it acts ; and consequently, so little exposes the system to reaction and relapse. But perhaps the safest and most successful practice, in the advanced stageof the disease, would be a copious use of the hot saltwater internally, both by potation and injection, for the reasons I have just given, while red pepper, mustard, and such like stimulants, were applied freely to the outer skin, in a dry form, with brisk, and continued friction ; in order to produce a counter irritation and general stimulation. If this practice should prove successful, the patient will be in c6mparatively little danger of consecutive fever, functional derangement or relapse. I repeat, however, that not being well acquainted with materia medica, I dare not speak with confidence as to the best articles to be exhibited in this stage of the disease. My remarks are founded entirely on what seems to mo to be the philosophy of the case, and strictly consistent with the principles of physiological pathology manifested; and I feel exceedingly 34 confident that if any pre-eminently successful mode of treating !hf» disease shall be discovered, it will be very simple. But it must be confessed, thnt there is at present np little responsibility resting on this point ; and every man who possesses anyconsiderable degree of moral sensibility, will hesitate and consider carefully and deliberately, before he utters even a conjecture, as such, on so fearfully momentous a subject ; knowing well, that if erroneous, it may cause the death of some — perhaps of hundred — possibly of thousands of his fellow creatures, who unfortunately confide in his opinion. [Note. Such is the text of the lecture, which I delivered in the Baptist Meeting House, in Mulberry Street, New York, in March, 1832, and repeated at Clinton Hall, in June following, about two weeks before the cholera broke out in the city. Having had no experience in this disease, I was then, of course, obliged to found all my opinions, as to the treatment of it, on what I conceived to be its evident principles of physiological pathology. Since then, as you all well know, the most terrible experiment has been made in this city, and by it, the doctrines which I taught, some months before the disease appeared in this country, have been fully and most signally demonstrated to be correct. I therefore no longer speak with painful uncertainty on the subject of the treatment of what is called the second stage of the cholera ; but with all the confidence that the most unbounded success can justify, I now boldly and earnestly recommend what I at first timidly suggested ; differing from my first prescription, only, in the addition of a portion of cider vinegar to the salt water; for which improvement I am indebted to another person, as I will state fully in the sequel. When any one suffers a violent attack, and is taken witluhe worst form of the disease at first, or has neglected or mal-treated the diarrhoea till violent vomiting, and convulsive spasms and cramps in the body and limbs, and burning sensations in the epigastric regions, &c. &c. supervene, let the patient take to his bed, and let a kettle of water be boiled as quickly as possible, and then put into an ordinary sized tea-cup, or some other vessel of the same capacity, one tea-spoon-full of good, common table salt,and one table-spoon-full of good cider vinegar, (remember it must be good cider vinegar,) and fill the cup with boiling water, and let the patient swallow this dose as hot as he can without scalding himself, and without sipping. If he sips it down, it will be more likely to come up again : but if he swallows the whole dose, as it were, at a single draught, it will almost certainly remain on the stomach, and at once arrest the vomiting and purging, and violent spasms, and in a few minutes bring on a profuse perspiration. If, however, the first dose should be thrown up, give the second dose of the same kind, and even the third, and more if necessary ; — but when it is properly prepared and taken, the first dose is very rarely thrown up, and the second never. Albeit if the spasms in some measure continue, it is well, at intervals, to repeat small doses, though the first dose should entirely arrest the vomiting and purging. If the case should be still worse, nnd the patient should be in what is called the collapsed state, in which, besides the symptoms already mentioned, there is no perceptible pulse, — the voice very feeble or entirely lost, and the skin cold and clammy, and of a dark purple color, &c, let 35 ti hot water, salt and vinegar, be given in the same manner as above ected, and let a like preparation be injected freely into the intestines, hot as the patient can safely endure it ; and let flannels be dipped into me of the same, and laid hot upon the stomach and bowels, and let the lbs be briskly chnfed with hot flannels, till the patient becomes quiet* lichwill soon be the case, and then let him be well covered, so as to pro>te the perspiration, which in a few minutes will be seen gushing copiousfrom all the pores of the skin. If any spasmodic affections or pains relain, let the patient, at intervals of from fifteen to thirty minutes, as the mptoms may be, swallow small doses of the hot salt water and vinegar; hieh, in such cases, should be prepared in considerable quantities, in c proportions of one measure of salt to four of vinegar, and sixteen of iling water. By this mode of treatment, the vomiting and purging will be arrested Est instantaneously ; the spasms will be subdued ; a profuse perspin will follow in a very few minutes ; the pulse will soon be perceptiind in a short time be restored to a regular action ; the skin will nally resume its natural color and warmth ; and in a few hours the nt will feel entirely free from the disease. Now the judicious ician, or nurse, may find it proper to administer a gentle cathartic, ted in its kind, to the peculiar habits and condition of the patient : r a dose of rhubarb and calcined magnesia, or rhubarb and calomel, ilomel alone, or castor oil, and then always strictly observing the ; regimen that I have already prescribed for the diarrhoea, and w 0:1 with a judicious diet, and all will go well. The wonderful and entire success that attended this mode of treatment during the prevalence of the cholera in this city last summer, fully justifies the confidence with which I now recommend it. Hundreds were relieved from that terrible disease by it, and in many instances after the njlse had been gone for a considerable time, and every symptom denoted Be last and most irremediable stage of the disease. Indeed though I ¦Bye taken much pains to ransack the city and investigate this matter, I lave not been able to hear of a single case of death from cholera where (his modo of treatment was fairly tried. Doctor L ,of Delancy ftreet, assured me, that after having failed entirely in every other mode of treatment, and lost every patient he was called to, he adopted the mode of treatment which I now recommend, and did not lose another patient, during the season. I have called on a number of persons in the upper part of the city, who informed me that they had the "collapsed stage" of the cholera to such a degree that all medicine was ineffectual, and the attending physicians pronounced them past remedy ; and then, as a last experiment, they took the hot salt water and vinegar, and were almost immediately relieved ; and soon recovered health. » The salt water and vinegar was first tried by Mr. George Bond of Orchard street, who about eighteen years ago was very severely diseased with the bloody-flux, for which ho tried various remedies in vain, till some one recommended the hot water, salt and vinegar, as above prescribed ;he tried this, and was immediately relieved. This fact, together with the notorious case of the thieves who protected themselves from the plague in London by the use of vinegar, led Mr. Bond to suppose that the hot salt water and vinegar would cure the cholera : and he soon had an opportunity of trying hid rcmcJy in his own family. For on tho night 36 of the seventh of July, his wife, who had been laboring under a neglected diarrhoea for several days, was taken with all the terrible symptoms of the " second stage." He sprang from his bed, and aa soon as possible, prepared and administered his remedy : and to his great delight and even astonishment, found that the happy effect much exceeded his highest hopes. After this he devoted almost his whole time through the cholera season to the sick, and administered his remedy to hundreds with entire success. Mr. David Woodman, who was himself relieved from a violent attack by Mr. Bond, seeing the wonderful effects of this remedy, spent much of the cholera season also in prescribing it to the sick, with equal success ; even in filthy and damp cellars, and among intemperate blacks and whites.] Is the Cholera contagious ? The question whether this disease is contagious, has been warmly agitated ever since the disease has attracted public attention ; and the reelings which have been excited by the controversy, have, there isreason to believe,caused medical gentlemen to shape and color their statements and reports, according to their favorite theories of contagion or non-contagion : though I trust that this has always been done without the consciousness on their part, of any intentional misrepresentation. In the technical language of controversy, there is a difference between a contagious and an infectious disease. A contagious disease is taken by coming in contact with, or into the presence of, the person diseased ; or at least within the sphere of the action of the morbific effluvium from the body of the sick : but an infectious disease has a cause which exists independently of the bodies of the sick, and may be taken with equal certainty, without coming in contact with, or even into the presence of, any person diseased. The main practical difference, and which, if true, is of very great importance, is, that however infectious the disease may be, yet, if it be not contagious, there is no more danger in visiting and nursing the diseased, than there is in avoiding them ; and quarantine regulations are entirely useless. A majority of the physicians who have turned their attention to the subject, in Asia and Europe, and in our own country, are, I believe, decidedly of the opinion that the Spasmodic Cholera is not contagious ; and in their sense of the language, their opinion seems to be confirmed by many strong facts : — while on the other hand there are many important facts, which seem to prove that, if the disease is not absolutely and literally contagious, its infectious character is such as greatly to increase the danger by personal intercourse. On the subject of contagion, however, I apprehend there is a universal error. We are told that there are certain diseases which are absolutely contagious ; such as small-pox, hooping-cough, measles, &c. ; but lam not prepared to admit the correctness of this opinion. Ido not believe that any disease to which the human body has ever been subject, is absolutely contagious. I believe that there was a time, when the smallpox, for instance, was entirely unknown among mankind ; and that it was originated in the human body by the violation of those laws of life which appertain to the highest state of human weifarc ; and being once originated 37 it was contagious to all those who were in the same general predicament of vital condition and susceptibility, — which had then become the case with almost the entire species : and lam confident that this is all true of every disease which we call absolutely contagious ; and consequently, that the human constitution is still capable of being elevated above the susceptibility to any contagious disease : and that thus, all contagious diseases may be extirpated from the human family. — Why is the smallpox robbed of more than half of its virulence by passing through the vital economy of a cow, or any other strictly herbivorous animal ? Is it believed that it would be equally subdued by passing through the vital economy of a strictly carnivorous animal ? Ido not know but that the experiment has been made ; but if it has not, it certainly is worthy of a trial. Some diseases, however, become contagious at a much higher state of the constitution than others ; but this docs not prove that a disease which is contagious only at a very low state of the constitution, is not as truly contagious throughout its own level, and all below, as is the disease which becomes contagious at a much higher state of the constitution. The only difference is, that mankind are more likely to be universally, and at all times, in the predicament of the latter than of the former : and hence some contagious diseases may prevail at all seasons of the year alike ; others may prevail more at particular seasons of the year, and others may prevail only at intervals of many years, and at irregular periods, when the protracted operations of numerous causes have brought a larger or smaller portion of the race generally, into their peculiar predicament. Still, however, as every contagious disease may spread over its own level, and all below it, so the disease which may become contagious at a much higher state of the constitution, will, at all times, be more universally contagious throughout the whole human family, than the disease which becomes contagious at a much lower state of the constitution ; because the former embraces within the range of its capabilities, a much larger portion of mankind, than the latter. Nevertheless, I say, the latter is as truly contagious within the range of its capabilities, as the former. From the view which I have taken of the nature and of the epidemic cause of the disease under consideration, it appears that it does not necessarily depend on contagion, nor infection, to propagate it from place to place. Powerful panic, or mental action, with the co-operation of other causes, which I have named, may actually originate the disease; and tho disease, thus originated, may, in certain circumstances, which always exist, to a greater or less extent, in large cities and towns, generate an infection of v most malignant character, and extensive influence ; and this infection will lay hold of those who are somewhat above the level of its origin : and may be conveyed to places, and communicated to persons, who otherwise would have escaped. But the extension and prevalence of the disease, in any place, when communicated in this manner, by infection, depend entirely on the character of the place, as to airiness and cleanliness, and on the condition and habits of the inhabitants. On the whole, therefore, whatever view be taken of the question, the propagation of the disease depends less on the absolute power of any pestilential dr exciting cause, than on the predisposition of the human system ; and 6 38 consequently, whether it be regarded as contagious or infectious, or even both, yet it is by no means absolutely so. But the fact whether it will be taken by an individual, depends on the coudition of his body ; and that condition depends very much, if not entirely, on his own voluntary conduct Panic and agitation, it is true, are involuntary, and, in very nervous people, will considerably disturb the functions of the system, in spite of their best resolutions and efforts to the contrary. Nevertheless, a proper regimen and correct conduct, and an entire abstinence from those pernicious preventives and remedies, which invariably predispose the body to disease, and very frequently become the causes of the diseases which they were taken to prevent, will very certainly preserve the body from any serious disorder. Means of Prevention. The topic which comes next under our consideration, is of a less uncertain character. Regarding the cause of the epidemic cholera as altogether mysterious, and the naturo of the disease as wholly inexplicable, the means of preventing it have been involved in equal uncertainty. Indeed, if I had not the utmost confidence in the honesty and even magnanimity of the Medical Faculty as a body, I should sometimes be compelled to suspect them of the most heartless and flagitious design and imposture, in order to produce a state of things greatly conducive to their pecuniary interest, if not their popularity. The bewildering and terrifying theories which have been promulgated by many in the medical profession, have been highly calculated to produce a state of the most painful uncertainty and distraction of the public mind, in regard to the course proper to be pursued for the prevention of this dreadful disease. The consequence must necessarily be, that in the general incertitude and trepidation, some will pursue one course, and some another : some will go to one extreme, and some to another ; while very few, in the Babel-confusion, will be fortunate enough to fall upon the truth. But the view which I have taken of this disease, distinctly indicates the mode of prevention : — a mode not only consistent in theory, but established by universal fact throughout the whole career of the disease. The rules to be observed, are plain, simple, and such as enlightened common sense, undisturbed by bewildering influences, would always dictate. In short, they are just such as would be proper to be observed at any other time, in order to preserve the body in the healthiest and best condition : with this exception, however, that our judicious caution to avoid disease, should always be equal to our liability to it. For instance : when we are in pleasant circumstances, and enjoying a cheerful state of mind, all the vital functions of the body arc performed with increased vigor and elasticity ; but when we are suffering grief, or painful anxiety, the functions are all depressed, and more easily disordered and deranged : — hence, substances, which the stomach may receive with impunity, if not benefit, in the former state, may cause indigestion and disease in the latter : — and therefore, we ought always, when oppressed with grief, or any other painful affection of the mind, to be more careful to keep up the good condition of our digestive organs and skin, by stricter propriety of diet, and by washing, friction and exercise, than when we are in a healthy and cheerful state of mind. And this is entirely true in 39 regard to all other causes, circumstances and influences, which depress the vital functions of the body : — and peculiarly so in relation to the Epidemic Cholera. Cleanliness of person, at all times highly conducive to health and comfort, is of the utmost importance, as a preventive of Cholera. During the prevalence of this disease, every thing tends to depress the functions of the depurating organs, and to render the purification of the blood less complete, and consequently, to predispose the system to disease. And when it is considered that the skin, in a healthy state, throws off, in the form of insensible perspiration, more than half of the impurities and effete matter of the blood, the importance of keeping it clean and invigorating it by friction, cannot bo doubted : and more especially when it is considered that the digestive organs partake of the* general condition, and sympathize with the affections of the skin. If, as I have endeavored to show, and as I fully believe, the Epidemic Cholera may be originated in any place where circumstances are favorable for it ; and if the action of the disease thus originated, may in consequence of filth, and confined and impure air, generate an infection which may become powerfully and extensively malignant and fatul, — then surely a clean and airy habitation, and street, and city, are also of exceedingly great importance, as preventives of this horrid disease. But this is a point of such obvious moment, that I need only to suggest it to reflecting minds. Exercise, of a proper character, and as often as maybe prudently, in the open air, is another preventive, which must not be neglected. By it, the circulation, and especially in the capillary vessels, is increased and invigorated ; a greater determination to the surface is caused ; respiration and insensible perspiration becomo more full and free ; the blood s more thoroughly purified and a larger portion of the oxygen of the atmosphere is digested and incorporated with the blood, increasing its vital energy and stimulating power ; the organs are strengthened, and all heir functions are more vigorously performed, and the tone of health, hroughout tho whole system, is improved : and thus the vital power of the body to maintain health and resist the action of noxious and pestilential agents, is greatly increased. A free intercourse with pure air, is of indispensable importance to health and comfort at all times, and more especially, during the prevalence of epidemic disease. Not only should every individual have access to pure air, if possible ; but every house, and particularly the sleeping rooms, should be well ventilated daily ; and the beds and bed-clothes should be thoroughly aired before the beds are made in the morning, that the impurities which they have imbibed from the body during the nighl, may pass off. It is also of the utmost importance that the natural appetites should be strictly regulated, and always kept in subordination to enlightened reason and moral propriety. These appetites are wisely and benevolently implanted in our natures, for the preservation of our lives, and for the continuation of our species : and when their exercise and indulgence are kept strictly within the range of their constitutional design, they contribute to our health, and are the rudimental sources of a very large amount of human enjoyment. But when, disregarding the constitutional laws on which they wero established, and the great ends for which they were instituted, we yield to an excess of their indulgence, and make sensual gratifications a principal object of our pursuits, and source of our enjoyment, they inevitably become the agents of disease and suffering to us : and always in proportion to the importance of the end for which they were implanted, and the extent to which their indulgence has transgressed the constitutional laws of propriety. Accordingly, we find thai, in the whole career of the Epidemic Cholera, dietetic intemperance and lewdness have been the grand purveyors to its devastating rage. In every couutry, the drunken and the lewd have fallen almost by hundreds and by thousands before this terrible destroyer ! — We are informed, that out of fourteen hundred lewd women in one street in Paris, thirteen hundred died of cholera ! In a single house, sixty of these wretched creatures perished by this disease. There is one point, however, connected with this general fact, which deserves more particular attention, as it has, 1 conceive, led to an erroneous, and to some extent, dangerous inference and conclusion. It is well known to those who have attended to the subject, that excessive indulgence in lewdness exceedingly debilitates the organs and general powers of the body, but the principle upon which this debility is induced is not generally so well understood. Simple debility has therefore been regarded as a predisposing cause of cholera, in those unhappy creatures : and hence, the general doctrine has been set up, that debility, by whatever cause, or in whatever manner induced, always predisposes to the Cholera ; and hence, again, the still more pernicious doctrine, that " a generors system of diet," (including a free use of animal food, and of wine, and even of brandy,) is the best preventive of the cholera. Thus one error springs from another, until there is a result of the most disastrous consequences to society, and then we begin to open our eyes to investigate the cause : but unhappily, we are too generally satisfied with ridding ourselves of tho immediate inconvenience, without ever pushing our inquiries to the generating principle ; and consequently, we continue on with no other real relief from the evil, than that which is found in a change of its mode or type. In regard to the case of lewd women, two important facts are to be noticed. In the first place, ninety-nine hundredths of those unfortunate creatures, are excessive in their use of intoxicating substances; and such is the inactivity and indolence and irregularity of their habits, that these substances are exceedingly efficacious in destroying their constitutions. In the second place, the debility induced by excessive lewdness, is alwaysjfar more the result of excessive excitement and irritation than of any other cause ; and the alimentary canal is almost invariably the very first to suffer from these irritations ; and to be brought into a state of debility, morbid irritability, and even inflammation ; and not unfrequently, the very worst forms of gastritis and enteritis are induced by excesses of this kind. This species of debility, though differently induced, constitutes the obnoxious predicament of that class of sufferers, concerning whom so much is said about their " meagre diet." It ought to bo known that muscular debility of the voluntary organs, and functional debility in the organs concerned in the general office of nutrition, are by no means identical. It is often the case, that the very means by which we diminish the muscur 40 41 hr power of the voluntary organs, increases the vital powers in the ncrf c* of organic life, on which tho body depends for its ability to resist the action of noxious agents. It is therefore true that the vital power of the body to resist the action of noxious agents, may be much greater in a. delicate female of little muscular power, than it is in a man of much greater muscular power. It may therefore be laid down as a safe doctrine, that that debility which results from excitement and irritation, whether caused by lewdncss, artificial stimuli, or any other means, exposes the system to the attacks of cholera and other diseases : while on the other hand, simple debility, not resulting from any of those causes which also induce a morbid excitability and irritability,— but constitutional, or caused by judicious bleeding, (if any thing might render it necessary) or by a regular course of abstemiousness, is almost infinitely more safe than that condition of the body which is produced by what is called v a generous system of diet." But it is not only the openly intemperate and the illicit, that injure themselves by their improper indulgences. No forms of civil law, or institutions of society, can save us from the evils which result from transgressing the constitutional laws of our nature. All excesses, therefore, beyond the real wants of our system, and purposes of our organization, — and equally when committed within or without the pale of civil institution — are dangerous to our bodily health and existence. Even things which in themselves are good and lawful when properly used, are, in their excesses, dangerous. The healthiest food which man can eat, may, by excess, become the cause of disease and death. Every appetite and every passion should therefore be held in strict subjection to enlightened reason, and moral propriety, if we would not increase our liability to be attacked by this terrible disease* A single paroxysm of anger, has been known to cause the most violent and even fatal bilious colic, and to bring on suddenly a severe attack of spasmodic cholera : and however modified in its degree, this passion never fails to disturb the digestive organs, and always tends U produce a morbid irritability of the nerves of organic life, and derangement of the stomach and liver ; and when frequent and violent, it often brings on inflammation of these organs. Of the effects of fear in predisposing the body to attacks of cholera, I have already spoken at large. This is the more dangerous, from its being, more than any other, an involuntary passion. Still, however, though we may not be able to suppress it entirely, we can do much to modify its action, and to counteract its effects. We cannot, therefore, be too deeply impressed with the importance of being on our guard in this respect ; for there is not a single premonitory symptom, if indeed there is a single symptom or effect, in the whole range of this disease, from its commencement to its termination in death, which may not be produced by fear ; and especially if, as is almost universally the case at such times, fear leads to the free use of the violent preventives and remedies ordinarily prescribed. During the prevalence of the epidemic spotted fever in New England, as I have before remarked, hundreds perished in this way : and instances were known in which, not only delicate and excitable females, but the most robust men, and even physicians, fell prostrate and almost lifeless, with all the apparent symptoms of a violent attack of that disease 5 but 42 which, according to their own subsequent confession, was entirely the effect of fear ; and had brandy and laudanum, in the enormous quantities then usually administered in such cases, been poured down their throats, they would inevitably have perished, as hundreds of others did, not with the spotted fever, but from overwhelming fear, and destructive quantities of brandy and laudanum. In this manner, beyond a question, thousands, if not millions of human beings have perished, during the prevalence of the present epidemic. Indeed, were I disposed to try the horrid experiment, I am confident that with the entire command of the press, and acquiesence of the physicians, druggists, &c. &c, I could produce five thousand cases of cholera, in the city of New York, in one week, — one half, at least, of which, would prove fatal ; and as little do I doubt, that if the cholera appears and prevails in this city, these agencies will, in no small degree, contribute to the calamitous result, even with the best intentions. It has been well said, that evils irremediable are best unknown ; and were the doctrine of fear, inevitable in its consequences, the public announcement of it would be Worse than cruel ; for it would be only aggravating, in the highest degree, the very evil which is deprecated. And from the manner in which some physicians have treated the subject, in regard to the epidemic cause, and the effects of fear, the most painful consequences have resulted. It is indeed, like taking children into a dark room, where nothing can be seen, and where the excited imagination is left to shadow forth the most horrid images, and solemnly telling them, that a hideous monster is in the room which has destroyed thousands of children, and will very probably attack them ; and few attacked by him ever escaped ; — how this monster moves — in what direction and manner he will come, and at what moment he will attack them, no one can tell ; nor can any one tell how they can avoid him : — but they must not be afraid of him in the least ; for if they are afraid of him, he will surely destroy there : nor must they hope to run away from him, for by such an attempt tiny might run directly into his open throat ! or when they least expected it, he might suddenly pounce down upon them from above. They must therefore stand still in thick darkness, and listen to all the terrible accounts of his havoc, and with perfect calmness await his mysterious approach. The view which I have taken of the general subject before us, presents this matter in a very different light, and renders it exceedingly important that it should be universally understood. For, while we are taught that fear increases our danger, we are also taught how it increases it, and therefore, how we can, to a great extent, if not entirely, counteract its effects. We see that fear seldom causes death directly, by its own overwhelming and exclusive power, excepting in those whose vital energies have previously been reduced very low by ruinous excesses or disease. We learn how it disturbs and depresses the functions of life, and arc taught how to counteract these effects by diet, exercise, cleanliness, employment, &c. And we learn, also, that fear may excite in our morbid sensibilities, and sympathies, most, if not all of what are called the premonitory symptoms, and therefore, we are warned against flying to the use of medicine for every pain or spasm we may feel, and taught that we must not prescribe for ourselves, except the simple regimen which I havo pointed 43 out, unless there is the most decided evidence of disease ; nor even then, if we can obtain the timely advice of a judicious and skilful physician, or some other intelligent person, whose judgment is undisturbed by our fears. Writers in Paris inform us, that almost every body in that city, has more or less of the premonitory symptoms of cholera, and therefore it is inferred that the epidemic cause is atmospheric : but it ought to be known that such a state of things may be produced by panic alone, without the action of any other cause ; and therefore, men ought not rashly to increase the horrors of this disease, by throwing the awfulness of mystery over the public mind. Finally, in regard to the mind and passions, we ought to endeavor to maintain the utmost composure and serenity ; and happy is that man who has that peace with God, which will enable him at all times, even in the hour of imminent peril, to cast himself upon the protection of his heavenly Father, with sustaining confidence. Diet. On the subject of diet, in relation to cholera, I have already said much ; but a correct system of diet is of so much importance as a preventive, that I consider it necessary to enter still farther into its details. One great truth in regard to this subject, should be constantly held in view. If the alimentary canal, with its functions, be not, by natural and >roper means, kept in a healthy and vigorous state, the health of the >ody cannot long be preserved. — As I have already remarked, almost all the habits and customs of civic life tend to debilitate the stomach and ntestines, and to impair their functions. The artificial modes of pre>aring food, and especially the pernicious compounds and concentrations, ire among the powerful means by which debility, indigestion, and habitual costiveness and diarrhoea are induced. It ought ever to bo remembered, that the human stomach and intestines are so constructed and adapted to their constitutional purposes, that there is between them and the food intended for them, fixed laws of relation, and these laws extend to the quality, quantity, and condition of the food ; and all violations of them, must inevitably result in injury to the organs, and through them, to the whole system which depends upon them for nourishment. Accordingly it has been fully demonstrated by the practical experience of all the generations of mankind, and by the most extensive and accurate experiments of science, that, when by artificial means, the simple, nutritious properties are separated from any article of food, and habitually used ibr any considerable time in the concentrated form, the stomach and intestines are debilitated, and their functions are impaired, and finally destroyed, unless the full effect is in some degree prevented by the use of some counteracting article of food at the same time. The potato, for instance, contains a certain proportion of nutritious matter: If the potato be well-grown, and properly prepared, it is a very healthy article of diet, and constitutes the principal subsistence of thousands of healthy and robust human beings : but if the nutritious matter should be artificially separated out, and given, however abundantly, to these same people, instead of the wholo substance of the potato, their digestive organs would soon become debilitated, and lose their 44 functional power; and their bodies would become weak and emaciated^ and die. The same is true of wheat, and all other kinds of proper food. Put any number of the healthiest and most athletic men .on a diet of the very best superfine flour bread, and water, and they could not very long survive. Debility of the alimentary canal, indigestion, costiveness, or alternate costiveness and diarrhoea, would ensue ; resulting in emaciation, general debility, and death. But if an equal number of men, of like character and circumstances, be at the same time put upon a diet of water and good bread, made of good, unbolted wheat meal, coarsely ground, their digestive organs will continue in the most healthy and vigorous condition, and the functions of the stomach and intestines will be regularly and healthfully performed, unless some other distinct and independent cause induces disorder. For a short time at first, these men may feel a sense of debility and lassitude from the absence of a more stimulating diet, to which they have been accustomed ; but this will soon pass away, and then they will begin to feel strong, and sprightly, and cheerful. This has ' been repeatedly demonstrated on the most extensive scale of experiment. The British army of more than eighty thousand men, according to the united testimony of all its officers and physicians, was relieved from almost every species of disease, and brought into a state of unusual health, by using bread made of coarse, unbolted wheat meal, for two years, near the close of the last century. A very intelligent sea captain of thirty years' experience in marine life, assured me he had always found that his men were much healthier and more active and vigorous, when they were fed on sea bread made of coarse meal, than when they used that which was made of fine flour. — Old whalemen declare that they always feel better and more vigorous and cheerful when they eat coarse bread than when they eat fine. I might go on and adduce facts by the hour to corroborate this doctrine : but it is not necessary ; it is so evidently and incontestibly true, that none but the culpably ignorant, and wickedly perverse, will contradict it. Bread is decidedly the most important article of diet used by civilized man; and so intimately is it connected with the corporeal and moral and intellectual interest of the human species, that it is scarcely possible to give too much attention to its kind and quality. The pernicious effects of superfine flour bread, in society, are considerably modified, and in some degreo counteracted by other articles of food used with it ; but still the evils resulting from the use of such bread, and especially when eaten fresh and warm, are vastly greater and more numerous than is generally supposed. If you would have bread which will in the highest degree contribute to your health and comfort, and prevent disease, you must take particular pains to procure the best of wheat, and have it thoroughly cleansed, and ground coarse, Without bolting ; and then have your meal, with sweet, lively yeast, made into light, sweet, well baked bread, which should be kept till it is at least twelve hours old, before it it is eaten ; and a greatei age would be better. If you will trust the public bakers to do all this for you, you may and you may not be well served. Ido not suppose they are worse than 45 other men, but they make bread and sell it for the profits of the business, and not for the sake of promoting your health ; and if they can increase their profits by usin£ an inferior kind of menl, they will be very unlike most other men, if they do not do so. Your only security, therefore, is in making your own broad ; for however honest and faithful the public bakers may be, their best bread is far inferior to the best domestic bread, and decidedly less wholesome. But whether you use the baker's bread or that which is made in your own house, you cannot be too careful to have it sweet, light, and well baked ; and of sufficient age before it is eaten. Heavy, sour, or musty bread, should by no means be eaten. There is no article of diet known in civic life, the use of which more invigorates the alimentary canal, and restores and keeps up the regular and healthful functions of the stomach and intestines, than tho bread which I now recommend. Unless counteracted by the concomitant use of the most pernicious articles, or by indulgonce in the worst of habits, it will relieve in a natural, and therefore, the only proper manner, the most inveterate costiveness, and habitual diarrhoea. In short, nothing is in itself more easy to digest, nor more healthfully and powerfully assists the stomach to digest other articles of food : while at the same time, it is one of the most nutritious and salutary articles received into the human stomach. I have frequently heard individuals complain of this bread, but I have, in every instance, been able, on examination, to trace the evils complained of, to other causes entirely distinct from the bread. We are told, however, that it is too relaxing to be safely used during the prevalence of the cholera. But the objection is founded in utter ignorance of the true principles concerned in the case. It will never relax the bowels, unless they are in a state in which such a relaxation is more healthful for them than otherwise, and then it never does it upon a principle which irritates or debilitates them, but the contrary ; and the laxness which it produces, is, during the prevalence of the cholera, almost infinitely more safe than the constipation which would obtain without it. In such a time, costiveness must be guarded against with as much care as diarrhoea ; but it cannot be habitually relieved by cathartic medicine without irritating and debilitating the alimentary canal, and thus increasing the liability to the disease. A single dose of salts, or any other improper or untimely cathartic medicine, may induce an attack. From the nature of thing 3, therefore, as well as from the most extensive experience and observation, I am fully convinced that no article of diet can be more safe and salutary, under all circumstances in which it >is proper to use solid aliment of any kind, and that none is more condu- I cive to the vigor, health, und good order of the alimentary canal ; and therefore, that none is better calculated to prevent the cholera, than the ¦ bread which I now recommend, when of such a character and used in such a manner as I have described. Objections which evince the most egregious ignorance, or stupid imbecility, or base dishonesty, have been raised against this bread by some who have happened to be permitted to be a discredit to the medical profession ; but happily their influence has been too limited to effect any considerable injury. Plain, boiled rice, coarse Indian-meal hominy, &c. eaten cold with a 7 46 very little good molasses or sugar, or with a small quantity of good milk, are also excellent articles of diet. There are several other farinaceous substances, which, in proper conditions and quantities, and at proper times, are safe and salutary articles of food : remembering always to avoid the concentrated forms, and unwholesome conditions of all articles. If butter is used at all, it should be only the very best, and then very sparingly, on cold bread, &c. ; but no other grease should by any means be eaten in any form. Pastry of every kind should be carefully avoided. A few of the milder fruits of the season, such as strawberries and peaches, when perfectly ripe, fresh, and sweet, may be eaten as a portion of the breakfast and dinner, by those who in all other respects conform to the rules which I lay down : but they must not be eaten in the evening, nor if they have been prematurely gathered, or have become in any degree acid by fermentation. All crude and unripe fruits and vegetables, of every kind, such as pine-apples, cucumbers, radishes, &c. — in short, every green vegetable, and almost every kind of fruit, fresh and preserved, should be avoided during the prevalence of the cholera, particularly by citizens who depend on the markets and the confectionaries for their supplies, and whose digestive organs are accustomed to flesh, and stimulating condiments and drinks. No salt nor shell-fish, of any kind, should be eaten : and in this city even frcslt scale-fish had better be avoided. Lobsters, in particular, are among the very worst and most dangerous articles of food ; and clams are but little better. They who have sanctified themselves from the use of animal food of every kind, had by all means, better continue to do without it. But they who have always accustomed themselves to a free use of flesh, and shall continue to do so up to the time of the commencement of the cholera in this city — (if such a fearful time shall come !) — if they cannot leave it ofi entirely at once, without feeling the want of it exceedingly, may eat a little broiled or roasted beef or mutton once a day, without any made gravy, and without any seasoning but a little salt ; and no second course or dessert of puddings, pies, fruits, &c. should be taken after it. Soup 6 of every kind, and especially flesh soups, should be strictly avoided. — Flesh soup, at all times bad, is peculiarly pernicious at such a time. It is only the concentrated form of some of the nutritious properties of the flesh, held in solution by the water ; and when it is introduced into the stomach, the water is taken up by the absorbents, and the concentrated properties of the flesh, together with the viscious seasonings, are left to tantalize, and irritate, and debilitate the alimentary canal, and thus always predispose to the epidemic cholera. All stimulating, heating, and irritating condiments of the table, such as the various spices, pepper, mustard, &c. &c. &c, should be carefully avoided. Tea and coffee are decidedly pernicious to health, and predispose the body to disease : they debilitate the alimentary canal, and the nerves of organic life generally, and impair digestion and peristaltic action : — in short, they always diminish the healthy vital properties of the tissues on which they act, and become the auxiliary and sometimes the principal causes of some of the worst and most distressing forms of chronic and acute disease ! — If indulged in excessively, they will become powerfully predisposing causes of the epidemic disease which is at 47 ?resent so much dreaded.* They who con cleanse themselves entirely rom their use, and recover from the effects of the change before the cholera breaks out here, will be fur better without them : and those who continue to drink them, should use thy landed in Quebec and began (as th-'v unquestionably did) to drink whiskey again, the cholera returned among them. And yet our citizens are advised to drink " generous wine, brundv, and gin," to keep off* the cholera! — I would not be the author of this advice for the wealth of New York ! Scarcely less erroneous in its nature, and pernicious in its tendency, than the alcoholic proscription, is tin; public recommendation to the citizens, to provide themselves with medicine for the cholera, that they may be prepared to administer according to prescription, at the very first indication of an attack. For six month* past, our newspapers have teemed with accounts of the cholera, with all the horrific details that can possibly be given. Every symptom of the disease lias been described and republished, times without number ; and those symptoms have been made to cover almost the whole fi^ld of our sympathies ; so that it is hardly possible to feel a pain or an direction, which does not come within some of the classifications of premonitory symptoms. The people of this country, have been contemplating the ravages and advancements of tliil disease, and expecting its appearance among themselves, with a fearful anxiety, whose influence on their bodies has been like that which impels the charmed victim of the serpent, to fly with horror into the open jaws of destruction ! — Thousands have deeply shuddered at the suggestion of their own fears, " 1 shall surely die with this awful disease !" It is impossible that such a state of things should long continue, without producing in every individual, a greater or less degree of morbid sensibility and morbid sympathy. And the mind, with unusual vigilance, will instinctively notice every pain and afiection of the body. Nothing more is wanting than the panic which will be produced by the announcement of the fata! presence of the terrible destroyer, to induce in thousands, and hundreds of thousands, sympathetically, most or all of the premonitory symptoms ! Are such people in a proper slate of mind or body, to prescribe or administer to themselves 1 But suppose a real attack, — what shall the sufferer take ? Have the medical fraternity prescribed to us v specific for this disease, in all its forms and stages ; and in all persons, habits, and conditions ? Through the whole fifteen years' career of this devastating disease, in Asia and Europe, and now in Canada, the most extreme differences of opinions, and modes of practice, and kinds of remedies, have been adopted by medical gentlemen of equal professional experience and reputation. Hundreds of experiments have been made, and scores of remedies have been publicly recommended by physicians. All this has found its way, of course, into the columns of our newspapers : and the Dumber of preventives and remedies, has been greatly augmented by the 60 gratuitous prescriptions of every meddling empiric and every officious editor in the community : — and to fill up, even to overflowing, another Pandora's box, without hope at the bottom, — that execrable portion of society — those wholesale venders of death — those tolerated butchers of thousands, the specific mongers, are advertising in our respectable papers, and in glaring hand-bills, posted up in every part of the city, their panaceas, and catholicons, and hygean pills, &c, as sure preventives and certain cures for the cholera ! In such a time of excitement and awful uncertainty, how shall the people ascertain which prescription is the best ? Alas ! they have erroneously concluded that the safest way is to procure all the different preventives and remedies and specifics, recommended by any and every body ! More than a million of dollars have been worse than thrown away by the citizens of New York within a few days past for medicines which are more to be dreaded than any pestilential cause of cholera. Thus supplied, as almost every citizen is, with an arsenal of self-destruction, — while drug and grogshops are yawning at every corner of our streets like so many craters of hell, to vomit out the lava of death on all who come within their range, — what more, I ask, is wanting than a powerful panic, to set this vast and complicated machinery of destruction into violent motion, to produce the most horribly calamitous results in this city? I tell you, my hearers, if there is not an interference of proper medical and civil authority, to arrest the course which these things are now taking, and will take in this city, the mischief which will ensue, should the cholera appear amongst us, cannot be calculated nor imagined ! But you ask again, — What shall we do ? we cannot avoid excitement, and we may not be able to keep free from panic in such a time of terror ! Follow the advice I have already given you. Carefully adapt your food, in quality and quantity, to the condition of your body and digestive organs and powers, partaking only of that which is plain, simple, nutritious and easily digested : — avoiding all concentrated forms and artificial mixture — all crude, heating, and irritating articles ; in short, carefully avoid in food and drink, every thing that is calculated, by any means, to produce an unhealthy irritation or irritability in the alimentary canal : remembering always that the greater your panic, the more peculiarly liable are you to such an irritation, and therefore, that many things which you have at other times indulged in with apparent impunity, may now prove fatal to you — and make it a regular duty to take your proper exercise, and to sponge and bathe your body, and rub your skin freely all over with a coarse towel, or good flesh brush, and endeavor to apply your mind to proper subjects, and avoid all improper exposures, and you will with great certainty be able to counteract all the causes of disease, both internal and external. " But shall we not be prepared for sudden attacks 1" Yes, so far as a proper government and conduct of body and mind can prepare you : and then you have nothing to fear from an attack which will not allow you ample time either to take such restorative measures as I have suggested, or to call in some experienced, temperate physician in whom you have confidence. " But suppose you should be suddenly attacked, what would you take, among the numerous prescriptions that are given to the public ?" Not knowing the peculiar state of your system, nor the precise nature of your 61 disorder, the medicine which you would take, might be more dangerous than the disease ! An ordinary diarrhcea or cholera morbus, which, by proper treatment would be easily managed, might, by a powerful dose of brandy and laudanum, be exasperated into the most malignant form of spasmodic cholera. Again I say, therefore, live properly — Tet preventives and remedies alone, and mind your own businsss ; and when the disease comes, it is time enough for you to call in a temperate and judicious physician. This advice however applies to citizens whose physicians are at hand, and who have apothecary shops within a few rods of them. People living in the country, and at a distance from a physician, may with propriety keep a few drugs on hand, but the emergency should be great, to justify their administering medicine without the special advice of a physician, unless it be something comparatively harmless, such as a dose of rhubarb and magnesia, or of castor oil, in case of diarrhcea. The Gentlemen of the Corporation of this City, will pardon me if I now take the liberty of pointing out to them, some of the important bearings of the general argument before us, on their public functions for the preservation of the health of the citizens. If I am correct in the view which I have taken of the subject, the cholera may, in certain circumstances and conditions, be communicated either by contagion, or infection, or both. The distinction, however, between contagion and infection, is of little importance in relation to the public duties of the Guardians of the City, in establishing precautionary regulations and restrictions. Notwithstanding therefore, all that has been said by medical gentlemen against quarantine regulations, there are many weighty reasons, in favor of their proper enforcement. It is true that this disease may break out and prevail in a place which is guarded by the most vigilant and rigorous quarantine and sanatary regulations : but this is far from proving that such regulations are useless. It only proves that while so much care Tins been given to the protecting of the place from imported disease, there has been too little care to prevent the causes which may originate the disease within the place. For, as I believe I have clearly shown, the disease may be both imported and originated in certain conditions and circumstances. A place therefore, in which it would not be originated, may be saved from the disease by proper sanatary regulations ; and a place in which it would be originated might be saved by a timely prevention and removal of the originating causes, and by proper quarantine and other sanutary regulations. But aa the cholera can neither be originated nor communicated absolutely, by any causes independent of the voluntary conduct of man, the more important duties of public functionaries appertain to the internal condition and conduct of society. Unfortunately however, in this land of glorious democracy and individual sovereignty, the civil power is much more competent to enlarge the privileges than to restrain the pernicious indulgences of the governed. It may therefore be useless for me to designate those duties of the corporation which are of paramount importance, if they would effectually preserve the city from the ravages of the cholera. Nevertheless, lam inclined " to speak boldly ns I ought to speak." In the work of purification, it is well enough to strew lime abundantly along the gutters, and in every unclean place throughout the city, in 9 62 order to neutralize those principles which cause offensive odors : but if the filth be suffered to remain, or if it is only gathered into heaps in the middle of the streets, for the carts to run over and disperse again, in clouds of dust, which settle upon the side walks, roll into every open door and window, and almost suffocate the citizens even at their tables, very little good will be effected by the use of disinfecting powders. But this, though of much importance in itself, is of very small consideration when compared with other evils existing in this city. It is in vain that you ransack every street, and lane, and alley, and yard, and private place, and cellar, and house, and strew your disinfecting powders like a snowstorm ; and scrape and sweep and v(ash, till every thing is clean enough to eat from, if stiil, those abominable seminaries of disease and death — the grog-shops, whether under the name of Groceries, or Taverns, or Coffee-houses, or Hotels, are permitted to deal out doses of destruction to the deceived and infatuated people. Unless the civil authorities of this city can shut up these places, or at least, stop ihe sale of intoxicating liquors, whatever else they may do to prevent the ravages of the cholera here, will be in effect, but little more than a public farce. But this is not all ! Our Augean stable is by no means cleansed, even when intoxicating liquors are removed. The drug-shops, if not entirely closed, should be open only to those who come with a recipe from a regular physician, and a rigorous injunction should be laid upon all apothecaries, druggists, and empirics, forbidding them to advertise or sell, any specifics, preventives, remedies, or medicines for the cholera, without permission from the Board of Health or from a properly constituted medical authority. The Press also should be silent on Ihe subject of the cholera, excepting in the publication of those statements, accounts or reports, which are made out by the Board of Health or by responsible physicians. All private communications, recommendations and prescriptions in tlie newspapers ; and all editorial articles or comments, excepting such as seek to allay the excitement, and encourage the people in a strictly temperate and virtuous course, should be entirely withheld. lam fully aware of the sensibility of the editorial corps, in regard to their rights and liberties in "this land of freedom,'" but I have also too good an opinion of most of them, not to believe that if they had a just apprehension of the mischief which flows from improper publications, and well-meant editorial officiousness, on such occasions, they would acknowledge the propriety of my remarks, and receive them, as they arc expressed, in the spirit of benevolence and philanthropy. But furthermore : the Corporation should strictly forbid the sale and exposure for sale within the limits of the city, of all pine-apples, cucumbers, radishes, and all other unripe, crude, and improper fruits and vegetables. In short, if the Corporation would be effectual in their efforts to preserve the city from the cholera, they should, if possible, prevent the use of every improper article of diet, both solid and liquid :—: — keep the city clean — introduce good water — facilitate the means of bathin — promote personal and domestic cleanliness and comfort — get the poor out of damp cellars, and other unhealthy places — not suffering them to crowd too many into a house, nor be exposed to confined and impure 63 air, — see that they have enough of plain simple food — keep everything calm — and rigidly enforce proper quarantine and other sanatary regulations. Before I close my lecture, I must caution my audience not to misunderstand me in regard to my dietetic recommendations. Let it be remembered that my advice is adapted to the present state of things. As yet the cholera is at a distance from us : whether it will appear in this city, or how soon, it is impossible for us to tell. I have supposed that you might have time enough to adopt my advice, and recover from whatever temporary prostration might result from any change in so doing, before the disease appeared among you. Were the cholera already here, and even now committing its ravages in the city, my advice would be, in some respects, different. I should say to you, beware of great and sudden changes under the influence of panic: beware of extremes !—lf! — If you have eaten flesh freely up to this hour, I would not say, abandon it totally at once ! but, diminish its quantity : let its quality be good, and let it be plainly and simply prepared, and eaten without made gravies, or much seasoning, and not more than once a day. — If you have used tobacco freely up to this hour, and cannot forsake it at once, without suffering greatly from its absence, diminish your quantity as fast as you can, prudently, and get clear of it entirely. — Tobacco has been said to be a good preventive, but such a notion is destitute of all truth. Cleanse yourselves therefore from this abominable and deleterious narcotic !—ln! — In like manner, also, get rid of your tea and coffee : in moderate quantities they are decidedly pernicious — in excesses they will powerfully predispose to cholera, and every other disease. — If you have drank distilled or fermented liquors freely up to this hour, and cannot abandon them totally at once, without prostrating the organic functions of your system, your condition is an unhappy one. If you go on and do not perish, your escape will be almost a miracle. It cannot be more dangerous to stop short, and let yourself down as fast as you can, with good tender beef-steak (well seasoned with salt and red pepper,) and good bread — such as I have recommended, taken in moderate quantities, as often as the stomach can easily dispose of its contents, and gradually diminishing the quantity of flesh and seasoning — and get down to the vegetable and water level as soon as you possibly can, and then pursue the system I have recommended in my present lecture. Finally, those who can adopt the system I have recommended, without a change which would seriously letdown, for a time, the functional action of their body, should enter into it at once ; but those who cannot, should get into it as soon as they prudently can. — Such, I say, would be my advice if the cholera were now raging around you and among you; but as it is not, my earnest entreaty now is, — remain not an hour in the Sodom of your pernicious habits and indulgences ! " Escape for your lives ! — Look not behind you ; neither stay ye in all the plain ! — escape to the mountain, lest ye be consumed !" APPENDIX. # The common opinion which prevailed in New York, for a considerable time preceding and succeeding the appearance of the Cholera in that city, was, that a generous diet of flesh and flesh soups, with brandy, port wine, and porter, was the best preventive measure that the citizens could adopt, to save themselves from the awful ravages of the disease : and while some of the physicians took a manly and noble stand against this ruinous error, too many of them on the other hand, gave decided countenance to it. Dr. Rheiulander, one of the physicians sent by the city to Canada to ascertain how to treat the disease, published his advice, cautioning the people against the use of distilled spirits but recommending the use of port w ive, and thus caused thousands of gallons, of a vile mixture of whiskey, logwood, and other abominable things, to be sold and drank under the name of port wine ; which was incomparably worse than the clear whiskey itself. This was soon followed by the appearance of an article in the Courier and Enquirer from Dr. Felix Pascalis, in which he says that " the ravages of the Cholera will probably increase in the city, until it has decimated, or even extirpated the whole class that subsist with little or no animal food." And again; — "as for preventive remedies, the reader will remember that the Delta of the Ganges is called the cradle of the Cholera, and that there the inhabitants do not live upon animal food ; that in China where animal food is scarce, the pestilence was most unspanng, and that at Hurdwar in 1783, 20,000 of the fasting pilgrims were cut off in less than a week, &c." The reasoning and deductions of the whole article were extremely loose and inconclusive and erroneous, — but they were ad captandum vulgus, and together with Dr. De Kay's and Dr. ftheinlander's prescriptions of brandy and wine soon became the vox populi of the city : while the columns of the news-papers daily contained advertisements recommending Swaime's Panacea, Hygean pills, and other whole* sale instruments of death, as sure preventives and remedies for the cholera. In such a state of delusion, and depravity, and panic, it was Very natural that tho most clamorous out-cry should be raised against the dietetic doctrines which I had (aught in my lectures. Every dealer in intoxicating liquors, including Hotels and Coffee Houses, — every druggist, and almost every butcher, and baker, and tobacconist and grocer, and flour dealer, and " free liver" in the city, felt deeply interested to save the people from the ravages of cholera by virtue of a " generous diet" of flesh, flesh soups, brandy, wine, porter, tobacco, coffee, tea, fine bread, &c therefore all were generously willing to lend their voices in the cry, that all the " Grahamites" were dead and dying with the cholera. The most egregious misrepresentations and unblushing falsehoods, were daily fabricated and busily circulated throughout the city, and even physicians who hold a respectable standing in society, boldly asserted, as a matter 01 their knowledge, that the " Grahamites" were dying by hundreds with cholera. At the same time the bakers who had undertaken to furnish the citizens with the kind of bread which I had recommended, in some instances, there is reason to believe, from the basest of purposes, and in others, from culpable negligence, suffered their bread to degenerate into the vilest stuffimaginable, and thus brought it into very great disrepute, and undoubtedly, in many instances, caused it to become seriously injurious to them that ate it. Such a mighty conspiracy against the cause of truth was' surely enough to try the courage and firmness of its friends in such a time of terror and death. Nevertheless there were some hundreds in the city whose steadfastness neither public clamour, and misrepresentation, and falsehood, nor professional assertions, nor any other cause could shake. They strictly pursued the course which I had pointed out, and calmly kept about their business, or humanely devoted themselves to the alleviation of the sufferings of the sick. Nor did they idly listen to tho misrepresentations and falsehoods which were daily kept on tho wing. Whenever these things received a definite form and locality, they were promptly investigated, and ascertained to be destitute of truth, and generally destitute of honesty. Mr,. Goodell, 66 tlio Editor of the Genius of Tomperancr, ferreted them out, and exposed them, with a diligence and boldness which were worthy cfthe cause of truth and humanity. On my return to the city, I made it my tirst business to ascertain us far as possible what had been the real effect of my dietetic system, in relation to the cholera. I immediately called at all those places where it had been said that " Grahamites" had died of that disease: and also culled upon all those physicians who, I was informed, had asserted that the " Grahamites 1 ," were all dying with cholera. Tho result of my inquiries was as follows : — The family of Mr. B — , in Madison street, had attended my lectures during the preceding winter, and partially adopted the dietetic system which I taught ; hut they continued in it only a short time ; and, some months before the cholera appeared in the city, the whole family, except the oldest daughter, returned entirely to their former habits of living, and were, most or all of them, cut off by cholera, except the oldest daughter, who continued pretty strictly on my system, and wholly escaped. The family of Mr. A , in James Street, had attended my lectures during the preceding winter, and left off coffee and tea, and did not use so much flesh as before ; yet, notwithstanding, he was, and long had been, habitually costive, he and his family continued to eat the fine, bakers' bread. After the cholera commenced, he continued to eat his beefsteak, roast beef, puddings, &c. and to eat only the fine flourbread, though very costive. He was a dyer, and dyed some | clothes of those who had perished of cholera. He took a dose of medicine as a preventive — became worse — sent for a physician — took his medicine, und was soon in a collapsed state, and died. Two of his children und an intemperate apprentice died also ; but whether of the cholera or the medicine, or both, is uncertain. The family of A. C , in Pearl Street, had attended my lectures during the preceding winter and spring; — they adopted my system, to a considerable extent, and Mr. C. and his wife found their health much improved by it. When the choleia broke out, however, they all, but one son, so fur yielded to what seemed to be medical authority, as to return to what was called a more "generous diet," and took their flesh dinners, with desserts, &c. The whole family, except the son, who strictly followed my rules, were taken with diarrhea 1, which, however, by being attended to, was soon checked, in all but the worthy old gentleman, who neglected his disorder, and suffered it to run on, occasionally taking some astringent or cathartic medicine, and continuing about his business, and eating as usual, and regularly taking two or three cups of strong coffee every morning before he rose. About the ninth day he took his regular dinner of flesh, &c , and after it ate freely of a flour pudding, with wine sauce, and to prevent any bad effects, took three glasses of port wine, according to the public advice of Dr. Rheinlander. The next morning he was very sick, and took his coffee as usual — grew worse through the day — fell under medical treatment, and died in a few hours. The death of this excellent man, caused more consternation than any other death which took place in the city during the sickness; because he was supposed to be a "strict Grahamite." There were a few other cases which were about as near to my regimen as those I have detailed : and these were the " hundreds of Grahamites who had dii;d of cholera." I then called on the physician who had asserted that hundreds of Grahamites had died of the cholera ; and asked him if he knew of a single MM of a person's dyingof cholera, who had strictly followed my system. He replied that he did not, and then gratuitously added, "and I never said that I did." Every other physician on whom I called, gave me the same negative answer, excepting one, who very confidently assured me that he had lost one such patient. I asked the name and number, and, on investigating the matter, found that the said patient had never attended my lectures, and in no respect any farther adop'ed my system, than to abstain from the use of ardent spirits : but the brother of the deceased, who took care of him through his sickness, without any touch of the disease himself, had heard some of my lectures, and to a considerable extent adopted my system of diet. The result of my inquiries was, that I could not ascertain that a single individual had died of cholera during the sickness in the city, who had, with any tolerable degree of strictness and propriety, followed the regimen which I had prescribed in my lecture on the cholera. Nor was I able to ascertain that more than two or three such persons had even had the slightest symptoms : while, on the other hand, there were hundreds who strictly followed my rules, many of whom were exposed in the utmost degree, and ytt not one of them had a symptom of the disease. I then advcitiscd in most of the papors of the city, that a public meeting would be 67 held at the Chatham Strret Chaprl, on which occasion I would expose nnd repel the various misrepresentation!" and calumnies which had been raised Igtfcwt my system, in relation to the cholera. The meeting was very large, nnd I met the objections which had been raised ; and challenged any one, to prove a single instance ofan individual's having died of cholera, during the prevalence of that disease, who had strictly and properly followed the regimen proscribed in my lecture on the cholera. This silenced the public clamor: but ever and nnon the smothered multerings of particular ones were indistinctly heard. I then addressed two letters to Philip Hone, Esq. through the Commercial Advertiser, in one of which I held the following language : " 1 have called, and still call, for the statement and substantiation of facts against my system ; but 1 shall not bo satisfied with popular and vulgar clamor, nor with indefinite and anonymous publications. 1 ask credible persons, under their own true signatures, to enme out and specify cases, if they know of any ; nnd give names, streets and numbers : — and 1 will honestly examine them, and if I find them true, I will publicly acknowledge them." Yet no one met this call, and with all this public and private inquiry, I have not been able to ascertain a single instance in which any individual has suffered either from cholera or any other disease, who has strictly and properly pursued the regimen prescribed in my Lectures. The following testimonies, on the other hand, are mostly extracts from much longer statements which 1 have received from the individuals whose names are given. Mr. Graham. Sir, — In stating my views of simple diet, as a means of preserving health and preventing disease, I must necessarily be brief for want of time. I think I have the most ample evidence of its salutary und conservative effects in my own person, of which, for the sake of the testimony — though 1 would not appear obtrusive — I will give some account. I had been afflicted, both before and during my medical studies, with that worst of diseases, chronic dyspepsia, from which I never obtained any permanent relief, until about eighteen months since, when I put myself on the simple mode of living recommended in your Lectures. For nearly a year, I subsisted principally upon coarse wheat-meal bread and milk, with great advantage to my health j when, happening to get some milkwhie.h tasted andsmelled of garlick, 1 became so disgusted with it, that, in May last, I exchanged my milk for spring water, which, with the coarse bread, has constituted my diet since. — During the past summer, and especially the cholera season, my professional duties were exceedingly arduous, and I often felt myself nearly worn out for want of rest and sleep. Yet through the whole sickness, I subsisted on one pound per day of coarse unleavened crackers, with some fruit and spring water, and experienced no disorder of the stomach or bowels, but enjoyed, and still continue to enjoy, better health than I have experienced before for the last fifteen years. On looking over my Notes of cholera cases, taken at the bedside of the patients, I find that the occasion of the disease, could be traced, in a very large majority of cases, either to confirmed habits of intemperance, or to come prominent act of imprudence. I speak here, of patients in both Hospitals and private practice. And furthermore, — in treating the disease, my experience is in favor of the most simple practice, and altogether unfavorable to the opium treatment. Many people — and among them, some of my own profession, have asserted that simple vegetable diet was conducive, to, and in many cases, had actually produced cholera. I have taken considerable pains to investigate these matters, and in not a single instance have I been able to verify their assertions: — but on the contrary, I have uniformly found that every person who has strictly and judiciously followed the system ot diet and regimen recommended by yourself, has not only escaped the cholera, but enjoyed very general good health. Yours truly, AMOS POLLARD, M. D. JV«w York, JVoc. 30, 1332. Sir, — Having attended your lectures in New York, last winter, and to a considerable extent adopted your system of living, I went to Montreal, and was there from the time the cholera broke out, until it had nearly ceased ; and although I did not in all respects live so simple as I ought to have done, and as 1 wished to do, 68 yet such was my confidence in the regimen I observed, that notwithstanding the very great numbers of dead and dying which I daily saw around me, I iVIt not the slightest alarm, till the destroyer entered our boarding house, suddenly snatched away two of its inmates, and so terrified the. rest, tlmt they all left, except myself and my cousin, who was also partially a disciple of yours. Even then my confidence was not diminished. Two letters which I wrote on the prevention and treatment of cholera were published in tho Montreal Gazette ; for their contents I was chiefly indebted to you. Your Ob't Serv't, JAMES DRYDEN. 52 Monroe St., New York, Jan. 10, 1833. Mr. Graham. Sir, — After having been grievously afflicted several years with dyspepsy, I attended your Lectures, adopted your system, and entirely recovered my health. Through the cholera season, I subsisted almost entirely on Graham bread, and water, and enjoyed the most perfect and uninterrupted health, nnd gained several pounds of flesh. Our family, consisting of ten members, who lived on what the doctors call a more "generous diet" of flesh, coffee, tea, fine bread, &c. all had pretty severe attacks of cholera, and some of them two and three attacks. My brother David, who lived as the rest of the family did, but used no spirits, went with me three several times through the cholera hospitals, to Bee the sick, and during the night following each-time, he had a severe attack of cholera, while I hod not even a premonitory symptom of the disease through the season. Yours truly, ALBERT WOODMAN. New York, May 16, 1833. Sir, — Myself, wife and sister, hod all been ofiiicted with poor health, and particularly my wife and sister, for many years before we heard your Lectures, ana adopted your system of living. Neither of us has eaten any flesh-meat since; which is now more than a year. We spent the past summer in the city, and never enjoyed better health than we did through the whole cholera season. That dreadful disease raged all around us, and cut off' many of our neighbors, and even came into our own house and attacked our mother, who did not live on your system, but ate flesh, &c. and I was much amongst the dying and the dead, and assisted in laying out and putting into their coffins at least a dozen bodies of those who had died of cholera, yet neither myself, wife, nor sister, had the least premonitory symptom of cholera, nor any other illness during the whole season. Respectfully Yours, EVANDER D. FISHER. No. 19, Essex Street, New York, Jan. 7, 1833. Dear Sir, — Beside the many other and great advantages which myself and family have derived from your valuable lectures, I will add, that we remained in the city during the cholera season last summer, and living near one of the cholera hospitals, we daily caw the dying and the dead carried by our door ; yet having attended your lecture on cholera, and living strictly on your plan, we felt so much confidence in your views that we had no dread of the disease : and we did not spend one cent at the drug-shops for preventives : and what is still more remarkable, — the, report was, that the Grahamites were dying like rotten sheep, and that in our family there was only one Grahatnile, and she had the cholera very bad ; and the rest of the family, who were not Grahamites, escaped : whereas, the truth is, that we were all living on your plan most strictly, except my mother, who thought she required the " more generous diet" to which she had always been accustomed, and she had a very severe attack of the cholera, while the rest of us had not a symptom, but enjoyed the best of health. Your sincere friend, WILLIAM MITCHELL. No. 437j, Broadway, New York, March 20, 18.13. 69 Sir, — Four members of our large family lived strictly on your system during the cholera season, last summer, eating no flesh, and subsisting principally on Graham bread ; they enjoyed excellent health, and none of them had the slightest symptom of cholera during the season ; while every other member of tho family had more or less of that disease. Yours, &c. p JVb. 13, Nortlimore St., JVew York, March 22, 1533. Sir, — During the prevalence of the cholera last summer, all our family had more or less of that dreadful disease, except myself: they ate flesh, &c. and I ate none ; but lived strictly on your system. And what, in nil probability, would have been my case, if that awful epidemic had found me in that condition of body in which I was, before I adopted your system of living ?— I verily believe, that, but for you, I should not now be among the living on earth. But, blessed be God ! lam not only living, but well. I have scarcely known an hour's indisposition during the past twelve months. And what a change is this, after having been afflicted as I have been for more than twenty years. Yours respectfully, Bowery, near jforth St., JV. Y. Feb. 19, 1833. H. WHEELER. Sir, — Since about the year 18 18, 1 have been afflicted with very feeble health. In the autumn of 1831, 1 commenced attending your lectures, and soon began to adopt your system of diet, and lived very strictly on it during the cholera season ; eating no flesh, and using the Graham bread. My health improved very much, and continued fiood through the summer. I saw many cases of cholera, and stood over several patients, and administered to them, and rubbed them, but had not a symptom of the disease myself. Yours, with sincere respect, F. L. WILSEY. JVew York, Jan. 17,1833. Sir, — Myself and wife had long been in very feeble health, and laboring under many serious symptoms of pulmonary consumption, when we adopted the system of living recommended in your Lectures; since which time, our health has improved exceedingly. Wo, and our children, and other members of our family, spent the cholora season in the city ; all living strictly on your system. Our immediate neighborhood was very sickly. The cholera was all around us, and the people died on every side of us. One man died nextdoor, so near to us, that I could reach my hand out of my window into his room; and the offensive smell of his body, after death, came in and scented our house ; and yet none of us had any thing of the disease. 1 have two apprentices both of which lived strictly on the Graham system through the worst of the cholera season, without the least indisposition. The older one then went into the country, where he spent two weeks, and lived quite generously on animal food, &c. and then returned to the city, and took the cholera immediately ; and had three doctors to keep him alive. The younger one continued in the city, living Btrictly on the Graham system. His health improved very much indeed during the summer, and he had not the least symptom of cholera, nor any other disease. Very respectfully yours, EDMUND VAN YORK. 98, Clinton St., JV«w York, Jan. 26, 1833. Sir, — Having been relieved, by your system of diet, from a miserable state of health with which I had been afflicted for years, I continued to live strictly on your system through the cholera season, making Graham bread the principal article of my food : and through the whole sickness eating fruit freely ; taking care, however, to get good fruit. I enjoyed excellent health through the season, without having a single premonitory symptom of cholera, or an unwell hour : nor have I had an hour's indisposition since : and at present, I enjoy the most perfect health. Yours with respect, S. VAN YOltX. JVo. 268, William St., JVtw York, June 17, 1833. Sir, — After having been afflicted with miserable health for many years, I was induced to adopt your system of diet ; and by degrees became more and more strict in my regimen, till I got on to a diet of Graham bread and rain water, exclusively. This regimen I observed rigorously through the whole cholera season, and not only 10 70 became wholly relieved from all my pains and ailments, but recovered, and enjoyed the most entire and perfect health; feeling strong, and active, and cheerful. My sleep was as swoet as a babe's ; and when I rose in the morning, I always felt fresh, and clear, and vigorous, and sprightly, as ever I did in my boyhood. During the cholera season, I was very much among the sick of that terrible disease. Several times a day, I visited a family who occupied a house belonging to me, (No. 62, James St.,) and of which five members died. I stood over the beds of the sick, handled their bodies, assisted in taking care of them, &c. and after the house was deserted, and others wore afraid to enter it, I went into the hgjuse, took up the beds, clothes, and other things appertaining to the rooms, from which the dead bodies had been removed, and carried them out of the house ; and was there three or four times a day, handling the things, &c, After this I visited several other families who were sick of the samedisease, — sat beside the sick by the hour, watched with them, rubbed them lifted them, &c. ; yet through the whole cholera season, I had not the least touch of the complaint, nor the slightest indisposition of any kind. Yours, &c. DAVID I. BURGER. JVeto York, Jan. 2, 1533. Cornor of Mott and Pell Streets. Sir, — Having been relieved from chronic disease of long standing, and restored to good health by adopting, pretty rigidly, your system of plain and simple diet ; myself and wife continued on the same regimen through the cholera season, and enjoyed the best of health, w.ithout a symptom of that or any other disease, until the cnolera season was nearly over, when we were induced to dine on fresh lumb. This brought upon me, a diarrhoea and severe pain in the breast ; my wife was more severely handled than I was; but by timely attention to our disorder, we were soon restored to health. A single dose of castor oil .was all we required ; and that is all the disease I have had, and all the medicine I have taken since I adopted your system, which is now two years ; during which time 1 have enjoyed most excellent health. Respectfully yours, HENRY R. PIERCY. JVew York, June 15, 1833. Office of the Genius of Temperance. Sir, — Benjamin Tjtler, who is, and has been for a considerable time, in my employ, has lived many years according to your strictest principles, and enjoyed remarkably fine health and spirits. He is now in his sixtieth year, and is still quite active and elastic. About five years ago, he went to England, where he staid five or six weeks. While there, he used animal food, which, he says, brought on a severe disorder of the bowels, and caused him considerable sickness. He has used no animal food since, but lived entirely on vegetable food in its simplest forms. During the cholera last summer, he enjoyed perfect health : and hearing it often asserted that the "Graham system" would not answer in cholera times, he used almost daily to walk through and about the Five Points, where the disease was raging in its most malignant and destructive character. He was often asked why he thus unnecessarily exposed himself. His reply was, " I wish to try the Graham system fairly: they say it will not answer in cholera times, and I wish to see whether it will or not." The old gentleman, however, had not the least symptom of the disease during the season. Yours, &c. DANIEL FANSIIAW. JV'eto York, Jan. 19, 1833. Sir, — In the autumn of 1813 I spent three months at Batavia, in the island of Java in the East Indies, where, by the use of bad water or some other means, my bowels became much disordered, and soon after I left there, a very troublesome diarrhoea set in, and, in spite of every thing I could do, it became an established chronic disorder, which has afflicted me with more or leas severity and constancy ever since, till I strictly adopted the system of diet which you teach in your lectures ; since which time — now about one year — I have not been troubled with that unpleasant complaint. Conscious, however, of this predisposition of my body to bowel complaints, I was fully apprehensive of my liability to suffer an attack of cholera, while that disease was prevailing among us ; and therefore, while I carefully aimed to take all proper measures to preserve my life and health, I at the same time endeavored to hold myself in readiness for any event. I lived strictly on what is called 71 the "Graham System," and, through the goodness of Divine Providence, I went through the sickly season, amidst uncommon cares and anxieties of business, without being at all disturbed in my own body by the cholera. Yours truly, WILLIAM GOODELL. .Yew York, June 17, 1833. Office of the Genius of Temperance. Esteemed Friend, — After having been sorely afflicted, for nearly thirty years, with n chronic diarrhoea, which was at times so severe, that it often confined me to my bed, ond sometimes brought me extremely low, I have been so much benefited by thy system of diet and regimen, that I was enabled to remain in the city through the cholera season, and not only to enjoy an entire immunity from that disease, but also, by virtue of my simple and salutary diet, to enjoy better health through the summer and autumn, than I had done before for more than twenty years. Thy friend, P. CORLIES, JVetc York, 6th month 17, 1833. No. 86, Madison Street. Sir, — I arrived in this country from Scotland, in November, 1831, in a very impaired state of health. I was tormented with continual head-ache, and was extremely weak ; and was so costive that I was obliged to take cathartic, medicine every day. As often as once a month, or six weeks, I was sevprely afflicted with diarrhoea, which hung on a week or ten days, and was exceedingly debilitating. My spirits were dreadfully depressed, and my miseries were very great. These difficulties, which had troubled me for some time in my own country, increased upon me here, and my wretchedness was intolerable, when I commenced attending your lectures, in April, 1832, and soon after began to live according to your dietetic rules for invalids. In a very short time after the adoption of this regimen, my complaints were all removed, and my health restored. During the cholera season I boarded in a section of the city where the cholera prevailed to a considerable extent ; and there was much of that terrible disease, also, wtiere I %vas employed as an engineer ; and most of the company employed with me were more or less troubled with it. The people in the house where I boarded, were constantly complaining and sick, but through the whole season I remained perfectly well, and had not the least indisposition, nor need of a particle of medicine. During the sickness I lived entirely on Graham bread and water, and occasionally fruit. I increased much in strength, and became quite vigorous, and able to perform much labor without fatigue. Yours, with sincere respect, JAMES WHITELAW. JVew York, Feb. 16, 1833. Sir, — I was living strictly on your system of diet and regimen, in excellent health, in New York, while the cholera was prevailing in the city, when I heard that my wife's family at Poughkeepsie, were afflicted with the cholera. One of her sisters had already had the disease, and was recovering, and her father had just died with it. I hastened to their assistance, taking care to carry with me a good quantity of Graham bread and crackers, upon which I subsisted while there; during which time another sister of my wife was .taken, and in a short time died. I was with her nearly all the time she was sick, and performed much of the labor about her after her death. I came off unscathed, and in the enjoyment of good health, wimout a single symptom of the cholera : while others, less exposed, were falling around me ; and all were more or less affected. Yours respectfully, JVew York, Jan. 12, 1833. JEFFERSON CRUGER. Office of the Genius of Temperance. Sir, — Myself, wife and children, having adopted your system of living, continued strictly upon it during the cholera season, and all enjoyed most excellent health, without a single premonitory symptom of that awful disease : while a young woman staying in our family, who had never heard any of your lectures, and was exceedingly prejudiced against you, and whose diet was roast-beef, beef-steak, mutton chops, &c. with bread, black tea, port wine, brandy and water, was attacked with every symptom of cholera. She was subjected to the camphor treatment, and the disease was arrested for a while i but about, the sixth day she was 72 taken again, — ngain became convalescent, — and ugain taken down, and with much difficulty saved. Her constitution appears to have been much shattered by the diseas*, or treatment, or both, for she cannot bear the least exertion without fatigue^ nor is she able to endure cold as before ; and until lately she has been obliged to resort to camphor or brandy, to assuage the pain she has felt. Yours, with every sentiment of respect, WILLIAM COOKE, No. 219, Hudson St., JVeto York, Jan. 14, 1833. Sir, — After having suffered in the most painful manner for more than three years, from what my physicians callatl a " disorder of the heart," I was restored to perfect health, by adopting your system of diet. My older sister, who had been subject to frequent turns of a billions complaint, also adopted your system with me, and was entirely relieved, and we went on together for some time, enjoying the most perfect and uninterrupted health, till my sister was tempted to break in upon her simple regimen, by taking a cup of tea, and then, in spite of my remonstrances, she repeated her transgression, and soon returned to her coffee, flesh, &c, till, in less than a week, she had entirely relapsed into all her former habits of living. But I inflexibly held on alone, in my straight and narrow path ; and by and by, the cholera appeared in our city, and in the midst of its fearful ravages, my sister was attacked. I stood over her night and day, administered all her medicine, rubbed her body, took her breath, and when she lny in a state of collapse, and said to me amidst her agonies, " Sister, kiss me," I pressed my lips to hers, and kissed her several times ; yet during the whole season of sickness, I had not even a symptom of cholera, nor any other indisposition. Yours, with respect and gratitude, A. M. PRIMROSE. AVw York, Feb. 19, 1833. No. 33, Rose Street. Dr. Tappan informed me that out of twelve house-pupils (students of medicine and young physicians) who assisted him in the Park Hospital during the prevalence of the cholera, Mr. Sharrock, who had lived more than a year very strictly on my system, was the only one who entirely escaped all symptoms of the disease. All the others being afflicted more or less, and some, pretty severely. Jan. 7, 1833. Dr. Lawrence, of Delancy St. informed me that he was acquainted with a young man who lived on the " Graham System" during the cholera season, and who took a great deal of pains to be amongst the disease, and to expose himself, for the purpose of proving the virtues of the system, and that he did not have a symptom of cholera through the whole season. June 15, 1833. I could multiply these testimonials to a hundred, from the statements which I have now on hand, received from persons of the most unquestionable veracity ; but I have already given enough to satisfy every candid reader that the hue and cry about the " Grahamites' all dying with the cholera," was not only without any foundation in truth, but was directly contrary to tho truth. In selecting the testimonials that I have sjivon, from the large number of statements which I have on hand, it will be observed that I have in many instances presented the cases of those whose previous health and state of body rendered them peculiarly liable to the action of any morbific causes which might induce cholera. 73 LETTER FROM MR. GEORGE BOND. Mr. Graham. Sir, — A bout eighteen years ago, I had a very severe turn of bloody flux, which proved exceedingly obstinate and unmanageable. The skill of my physician was completely baffled, and his medicine seemed wholly ineffectual. Clear blood ran from my bowels in alarming profusion, and nothing seemed to have any effect to stop it. My physician finally declared that he could do nothing more for me ; and to all human appearance I must die with the complaint. At this crisis, some one recommended the internal use of salt and vinegar and hot water. I know not why it was, but I was very favorably impressed by the suggestion, and had a great desire to try the prescription. My physician said it could do me no hurt, if it did me no good. I therefore had some immediately prepared in the proportion of a tea spoon full of salt, a table spoon full of good cider vinegar, and a tea-cup full of boiling water, and I took about half a table spoonful of this mixture every five minutes. I was immediately benefited by it, — the flux ceased, and I was soon restored to health. As soon as I heard the cholera was in this country, I began to read the accounts of it, and it struck me that the salt and vinegar and hot water would be the best possible remedy for it. With thi3 impression, I called on Dr. L , (at the corner of Sheriff and Delancy streets) and asked him if there was no cure for this disease. He said there were various modes of treating it, but no specific remedy had yet been found out. I told him, I believed I could cure it. He asked me how. With salt and vinegar and hot water, said I. Dr. B , who had come in while we were talking, replied that vinegar would not answer at all in the cholera. I told him that I wished to Heaven that some of my own family might have the cholera that night, so that I could try my remedy ; for I was very confident it would cure the disease. This was sometime in the latter part of June, near the last of the month. My wife had been about nine years afflicted with poor health, and a partial alienation of mind; and had been subject to frequent turns of diarrhoea. About the fourth of July, a diarrhoea came upon her, which we thought one of her ordinary turns, and paid no particular attention to it. On the night of the seventh, at about one o'clock, she woke me, and with a perfectly rational mind, said to me, "I am dying." I laid my hand oa her, and found she was cold as death,, and covered with a cold clammy sweat, and soon ascertained she was violently vomiting and purging, and dreadfully cramped and convulsed. I sprang from my bed and as quick as possible, kindled a fire and put over a kettle of water ; and then called up my little son and sent him for doctor L . In the mean time my wife was so terribly handled with the disease, that I could not mistake its character. I was sure it was the cholera, and I was exceedingly alarmed at its awful violence ; for I feared that nothing on earth could control it. As soon as the water boiled, however, I prepared a dose of salt and vinegar and hot water, and gave it to her ; and with equal astonishment and delight found that it arrested at once the vomiting and purging ; I then dipped some flannel in a mixture of the same kind and put it hot over her stomach and bowels, and in less than fifteen minutes her cramps and spasms were all removed, and she was in a very profuse perspiration, and quite at ease. I repeated the dose of salt and vinegar and hot water once or twice afterwards to keep up the perspiration. My son returned and said that the doctor told him that he knew nothing what to do if he came, and therefore it would be of no use for him to come. By morning, my wife was able to sit up, and after the operation of a dose of castor oil, was soon restored to her ordinary health ; with much less alienation of mind however than before. I was now fully confirmed in my confidence in the efficacy of the salt and vinegar remedy for the cholera ; and called again on Dr. 74 L , to state to him the results of my experiment. He was much surprised to hear that my wife was still living and doing well, and that I had treated her,only as I had. The cholera now began to prevail pretty extensively in the city, and I devoted the greater part of my time through the whole season of sickness, in visiting the sick, and administering my simple remedy to them : and invariably with entire success, in every stage of the disease ; and many who were cured in this manner went out also, and administered the same remedy to the sick with the same success ; so that I may safely say that hundreds were the subjects of this treatment. No less than fourteen, of my own and my brother's families, were severely attacked with the cholera, and all were cured by this simple remedy. My son, 12 years old, and the son of our neighbor, Mrs. D , a widow lady, about 14 years old, were together, and ate green apples one afternoon, and at about four o'clock, the next morning, both of them were violently attacked with cholera. I gave my son the hot salt water and vinegar, which soon relieved him, and in two days he was able to be about his business again. Mrs. D sent for a physician for her son, and he was put under medical treatment, and very soon went into a collapsed state. I called the next morning to see him, and found him in a most awful condition. His symptoms were extremely violent; death-like coldness, violent vomiting and purging — powerful spasms all over ; and the doctor told me that the pulse had been entirely gone for five hours. I ordered some boiling water, and put in my salt and vinegar in due proportions, and administered it in the form of a potation and injection, and dipped flannels in it, and applied them to his body, and rubbed his limbs with hot flannels ; and the violent vomiting and purging and cramps were soon arrested, and the patient began to perspire very profusely, and in forty-fivt minutes, his pulse beat sixty times in a minute with a full, fair stroke ; and the patient was doing as well as could be wished. Some slight spasms remained in the extremities, but they were fast yielding to the influence of my treatment. At this juncture Dr. C came in, and ordered the boy, profusely sweating as he was, to be stripped and rubbed all over with mercurial ointment. Healso ordered large doses of mercury. I told him the boy was doing well, and as sure as his directions were followed the boy would not live an hour. But he disregarded my remonstrance and persisted in his course. The unhappy boy entreated his mother not to follow the doctor's prescription, and said it would kill him ; but she, full of anxiety and alarm, yielded to the doctor's authority. The poor boy begged me to come to him, which I did, and he threw his arms around my neck and kissed me, and said — " you have done all you could for me and I thank you for it." In a short time after he took the powder which Dr. C ordered, his vomiting, purging, and cramps, returned upon him and soon became as violent as ever, and his pulse again ceased. Dr. W now came in, and seeing the state of things and learning what had been done, he turned to Dr. C and said to him, " you have killed that child !" Then turning to me he asked if I could not raise him again. — I told him it was too late. In forty-five minutes after the patient was put under the treatment of Dr. C — , he died. Soon after this Dr. R. came for me about midnight and wished me to go with him and see a patient (in Suffolk Street) which he said was very bad, and he could do nothing with her. He said he had had a number of patients in the same neighborhood, and they had all died in spite of every thing he could do. I went with him and found a woman in the most terrible agonies I ever witnessed. She was vomiting and purging with shocking violence, and her body and limbs were horridly drawn up and distorted with cramps. Several persons were trying to relieve her by rubbing her, but she seemed as though she was possessed by an infuriated fiend which was endeavoring to torment her to the utmost. I treated her in the same manner I had Mrs. D 's son, and in less than twenty minutes she was quietly perspiring in her bed, and the neat day she was able to be about house : and in two or three days more, was well. — On the same night, a woman died in the room above her, of whose case I did not know till after her death. A. P., in Grand Street, had the cholera with great virulence ; several physicians visited him, but Dr. R. had the principal care of him: but none of them were able to arrest the disease in the least degree, and the patient sunk into an extreme state of collapse ; and Dr. R. said he must die in spite of all earthly meant to save him. In this state of things, I was sent for, and administered my simple. 75 remedy, and the patient was almost instantly relieved ; and in a few days was about his business. His wife also had the cholera, and was cured in the same way. — Soon after this I was in at Dr. L.'s office, and a Mrs. D. of Willet Street came in for some medicine, and said that her husband had the cholera very bad indeed. She said he had been out on watch the night before, and as he did not come home at his usual time in the morning, she felt uneasy about him, and went down town after him, and found him in a back yard in a dreadful state of the cholera: he was unable to stand, and she got a hack and brought him home, and called in a physician as soon as possible ; but the doctor had not yet been able to check the disease, and she feared lie would die. Dr. L. told her she had better ask me to go and see him. She was afraid of offending her physician — Dr. D., and did not then request me to go, but soon sent after me. I found Mr. D. in a truly shocking state : his skin was a dark violet-blue, — his vomiting, purging, spasms, and other symptoms, were awful beyond description. Dr. D. was giving him powerful doses of medicine, but without the least favorable effect. Soon after I came in, he gave orders how to give the medicine, and said he must go and see some other patients, and would be back as soon as he could. The Dr. had scarcely left the door before I ordered some boiling water, and without loss of time administered my simple remedy to the sufferer. When the doctor returned he found his patient lying quietly in his bed, perspiring profusely, — no vomiting, no purging — no spasms, — skin natural, and scarce a symptom of cholera about him. The doctor was surprised and delighted at the happy effect of his medicine, and said it had done wonders, and the patient was doing finely, and would get well. He thin told us how to proceed, and again went to visit other patients. But his second orders shared the fate of his first — not a particle of his medicine was given during his absence, nor any thing else but the salt, and vinegar, and hot water. Mrs. D., however, thought it not best to let him know any thing about it; and when he came again, he pronounced the patient safe, and congratulated himself very much on his success in such a very violent case. I now left the house in company with the doctor, and oegan to talk to him concerning the treatment of the cholera, and told him I believed I could cure every case, if I could have a fair and timely opportunity. The doctor turned and looked at me with an air of great contempt, and exclaimed, in a sneering and emphatic manner, " How, in the name of God, can it be that you, an unlearned man, should know how to cure the cholera, when our most learned and eminent physicians cannot do it?" Having said this he left me abruptly, and there our acquaintance ended. — William A. D. however, soon recovered his health, and is now living and well. J. V., who had always habitually made a free use of ardent spirits, had the cholera very severely. The cramp in his limbs was so excessively violent that it drew his flesh all up into knots, some of which remained for six weeks. He took various medicines without the least effect, and when it was supposed that he was past all possibility of relief, he took the hot salt water and vinegar, and was almost instantly relieved, and soon got well. I could detail a great number of similar cases, but suffice it to say that in more than a hundred instances where I administered this remedy, I never knew it to fail of complete success in one case. I went oneday with Dr. R. into Slam's buildings in Delancy and Suffolk Streets, and there I saw the most horrid scenes I ever witnessed on earth. AH kinds and colors were crowded together, — the sick, the dying, and the dead. In one vacated room, the dead body of a negro lay rotting on the floor ; — Mr. S. of Second Avenue, went and covered it over. — Another man came and looked in at the door, and the next day he died. Mr. S. was continually in the midst of the cholera, and in the filthiest places where sickness and suffering were to be found. He used the precautionary measure of washing his body frequently in vinegar, and, I believe, wholly escaped an attack. — But I have dwelt long enough on these scenes of suffering and horror. Yours respectfully, GEORGE BOND. JVexo York, Jlpril 7, 1833. 76 ' P. S. I ought to hare stated, that after having extensively proved the success of the salt and vinegar remedy for the cholera, I went to a number of our city editors, and tried to get them to publish it, but they all refused to do so, except Mr. Webb, of the Courier and Enquirer. He published it, and not long afterwards received a letter from Norfolk, Va., stating that the salt and vinegar remedy had proved the most successful in that place, of any thing which had been tried. G. B. Note. Most of the persons referred to by Mr. Bond as having had the cholera, I hare called on, and heard from them a full confirmation of Mr. Bond's statement. S. G. From the Genius oj Temperance. GRAHAM MEETING. We give below, the proceedings of the meeting of the friends of the Dietetic system, taught by Mr. Graham. These proceedings will serve as a memorial, at home and abroad, of the views of a portion of our citizens, on a subject which haselicited no small degree of feeling in this city, and elsewhere. To persons unaccustomed to notice the winding labyrinths of human nature, it would appear strange that the advocacy of a particular system of diet, should encounter the opposition, misrepresentation, and prejudice, that have recently been witnessed. The result now recorded should serve as an encouragement to those who are called upon to advocate unpopular truths, and as a salutary warning to such as are liable to use and — peradventure — expend their stock of influence, in the fruitless task of retarding popular improvement. idPMeeting of the friends of Mr. Graham's Lectures. — The undersigned, a committee appointed for the purpose, hereby invite a meeting of the friends of the Dietetic System taught by Mr. Sylvester Graham, to be held at the lecture room in Clinton Hall, on Thursday evening, the 18th met. at half past 7 o'clock, to adopt resolutions expressive of their regard for the principles taught by him in his late course of lectures, and to afford him some testimonial of their high sense of his important labors. Abraham Bell — Austin Dickinson — Walter Underhill — Arthur Tappan — Solyman Brown — Eleazer Parmley — James Hall — Robert G. Fairchild — Joseph Titcom — Samuel J. Hunt — William Mitchell — John B. Jansen — Smith Lawrence — George Corlies — William Doane — F. L. Wilsey — James Smith — A. Sanger — Henry A. Lambert— Albert Woodman— John West— R. Griffith— R. L. Smith — Abijah Smith— Mahlon Day— A. A. White— John Burdell— A. A. Fairbanks — William B. Van Nortwick — Samuel Sloan — T. J. Sawyer — Jehiel Parmley — Truman Roberts — David Wood — Amos Keekr — Amos Pollard — Elihu Blake — R. N. White — Henry Fitz — A. B. Durand — Joseph Perkins — John Dodgson — Jonathan Thorn— John H. Ferris Howard— H. R. Piercy— William Goodell — J. C. Jenkins — Joseph Allen — Jarvis F. Hanks — R. I. Polhamus — William C. White. JVew York, April 16 ; ng in the evening. -k 13. Exercise. Every ¦ boarder should walk or ride on horseback, c some other active exercise, iVom thirty to sixty minutes every morning before breakfast, in the open air, when the weather will permit, and when it will not, gymnastic ejrprcises shouldibe within doors. Brisk walking, continued till a gentle ]*u»piration is prbduced, is perhaps the best exerci»e for the human body, especiaW, if it be varied with an occasional leap, run, hop, &c. to give increased exercise Jo the abdomftfal and thoracic viscera. Horseback riding is very good, if well re wlo ted — there: is great art in riding, so as to derive the greatest advantage to flic bowels, &c Still, however, smart walking, running, wrestling, boxing, &c. c.i