UNITED STATES OF AMERICA * MB * * • FOUNDED 1836 WASHINGTON, D. C. GPO 16—67244-1 COLLECTION OF PAPERS •OK THE SUBJECT OF PREVALENT IN THE UNITED STATES Fn» *• FEW YEARS PAST. COMPILED BY NOAH WEBSTER, ?J/JV. MEMBER OF THE SOCIETY FOR PROMOTING AGRICULTURE, ARTS AND MANUFACTURES IN THE STATE OF NEW- yORK, AND HONORARY MEMBER OF THE HISTORICAL SOCIETY IN BOSTON. N E w-r 0 R K: s *.y +fi * CO. N°. 40, PINE-STREET. _I?96._ [CNTERED ACCORDING TO LAW.] • To BENJAMIN RUSH, M. D, PROFESSOR OF THE INSTITUTES, AND OF CLINICAL MEDfc CINE, IN THE UNIVERSITY OF PENNSYLVANIA. ■ I, HY general liberality of fentiment, together with tftk unparalleled manner in which thou durfl, in the noble caufe of humanity, to introduce innovations in the treatment of the Epidemic Fever of Philadelphia in 1793, amidfl the perftcuting fliafts of thy opponents, point thee out as a mofl proper patron for the free thoughts advanced in the following pages. Befides this, Ifliould confider myf'elfgreatly deficient, was I to neglect this opportunity of acknowledging the high fenfie. of gratitude I entertain for the benefit received, not only from thy valuable public inflrutlions, but alfo from thy ever ufeful private converfations. Wifhmg thy long continued and increafing u/efulnefs,. in thy profeffwn and in the diffufion of Medical knowledge, I remain, With refpetl and efleem, Thy Friend, ^ c/al&ntlnc zfeaman* t T O John Broome, Robert Bowne, Gabriel Furman, Nicholas Carmer, Andrew Van Tuyl, Isaac Stoutenburgh, John Campbell, Samuel Bard, Robert Lenox, George Janeway, and Theoph. Beekman, Nath. Hazard, Surviving Members of the Committee of Health of New-York for 1795— Whofe undaunted attention to the objecls of their appoint- ment, and whofe perfevering care for the relief of their affliclea Fellow-Citizens, miifi, no doubt, have been followed by the gratifyingfienfe ofwett done, in their own bofoms :—Biffed be their reward. As the following obfervations were drawn up partly at their folicitations, and as the ideas and opinions advanced in them, are confidered as meriting their ferious attention, they are mofl refpetlfullyJubmitted by Their Friend and Fellow-Citizen, THE AUTHOR. preface. 1 HE utility of accurate Hiftories of Epidemic's to the improvement of medicine, has never been doubted from the time of the early and valuable pub- lications of Hypocrates, to the late and no lefs judi- cious obfervations of Dr. RuOi: but as the Yellow Fever has been fo accurately and fully defcribed and treated of by feveral phyficians in the Weft-Indies, in Philadelphia, &c. it may be thought entirely fuper. fluous to give any account of it as it appeared in this city. Fully fcnfible of the force of this remark, I long declined attempting any thing of the kind; but as feveral facts have occurred to me, a general know- ledge of which I confider as highly interefting to hu- manity and of importance to the community at large, and efpecially to the inhabitants of this city, I am finally induced to fubmit them to the confideration of the public, particularly as the Medical Society, which had made fome progrefs in the bufinefs, have declined the profecution of it. The many accounts and complete defcriptions al- ready given of this difeafe, feem to render it unne- ceffary to enter into a minute detail of its feveral fyrnptoms in this place; I have therefore been very fhort upon that part of the fubject, referring the more [ viii ] nice inquirer to the beforementioned authors, particu- larly to Dr. Ruth's account of it, as it appeared in Philadelphia, in 1793, where he will find its various appearances very particularly and accurately deli- neated. As the following obferva'dons have originated al- moft entirely from facts and circumftances of the dif- eaie, as it appeared in this city; the reader will find himfelf much deceived, if he looks for references to long catalogues of eminent authors, or for an elabo- rate account of the difeafes of the Weft-Indies, pes- tilences of Europe, or plagues of Afia: and as my conclufions are drawn chiefly from cafes and occur- ances, that have come within my own perfonal know- ledge, (which favored by my local fituation in the center of the Epidemic, and my providential preser- vation from its influence, till it was nearly extinguifh- ed, were confiderably numerous) he will alfo find that my remarks have not been much either influ- enced or fupported by the uncertain communication of my brother practitioners or other citizens; hence, if decided and undoubted facts, fliall hereafter appear which fhall disprove them, my error fhould be affig-n- ed only to my general fcepticifm reflecting current medical reports, and the limited nature that I have Impofed upon my fources of information. As fome thoughts which I have advanced, are de- >■•'"! :dly nppofed to the comn:cn ftiif-: of th? faculty ir general, I wifh it to be confidei that they are not the offspring of any favorite tL ^ry, or influential hypothefis; for I had heretofore been taught and be- lieved very differently, till the ftubborn obtrufion of facts upon my mind, forced me to change my opi- nion. I am well aware of the lofs of reputation that I may fuftain, from attempting, in the courfe of this effay, to fupport opinions which are very unpopular with the inhabitants of this city; however, the im- portance of the fubject, has fwallowed up all perfo- nal confiderations, and determined me freely to com- municate what I confider as highly effential to their welfare; and I fhall be richly paid, if my temerity fhall in the leaft degree, tend to the prevention of a difeafe, which in its partial* operation, in lefs than three months, fwept off upwards of {even hundred of our fellow-citizens; which fhould be fufficiently alarming to put us upon our guard in future, for fhould it again arife, in a feafon more favorable to its fpreading, perhaps its more univerfal devaluation will not be checked till it has numbered thoufands in its mortal lift. B * It being chiefly coqfined to a particular part of the city. A n ACCOUNT OF THE EPIDEMIC YELLOW FEVER, &c. Of the State of the Air, and Difeafes preceding and accompanying the Epidemic, and a Hifhry of the Difeafe. Jl ROM the tables of Meteorological observa- tions, inferted immediately before the confiderationt on the caufe, of the difeafe, it appears, that in the be- ginning of the fixth month (June) the weather was pretty warm, but became more moderate on the feventh and eighth days, and that its temperature was Suddenly increafed on the 9th of the month, railing the Mercury 12- degrees in Fahrenheit's thermome. ter in the fpace of twenty-four hours; it was warm on the tenth, then became cooler for four or five days, after which time it continued very warm and fultry for feveral days; on the 19th the thermometer flood at 87 °, and varied between that and 69° the re- mainder of this month—we had rains on the 2d, 1 ith, 20th, 24th, 25th, and 30th. The mean tem- perature of this month was 73°** * Thefe were the ftates of the thermometer at one o'clock, f\ M. ■■•"•/ 2 AN ACCOUNT OF THE It gradually became cooler for the firft five days in the feventh month (July); on the 6th the mercury rofe to 8 30, which was 130 higher than it flood the day before; the next day it fell to72°; after which, in the courfe of fix days, it rofe to 890 without any material fudden change; the weather then moderated in fome degree, fo that in the laft nine days of this month it did not rife above the 8o° and in one of them it flood at 68°—the mean temperature of this month was 81 °: it rained on the 3d, 1 oth, 18th, 23d, 24th, 27th, 30th, and 31ft. The thermometer flood near 900 moft of the time during the firft ten days of the eighth month (Au- guft)3onone day it was upwards of 930; in the re- mainder of the month it varied between the 60th and 88th°—great part of this time it was above 8o°, and there were but a few days wherein it was below 7 20; the medium temperature of this month was 830; we had rains on the 3d, 9th, 10th, nth, 12th, 13th, 20th, 21 ft, 23d, and 31ft days, and feveral of them were very great. The firft week in the ninth month (September) the mercury remained between 70 and 750; in the Second and third week it varied but little, one way or the other, from 8b °; but we had fome cool days in the latter part of the month, the mercury being as low as 580 on the 22d and on the 30th; mean tem- perature about 730; we had five rainy days, viz. the 2d, 7th, 13th, 19th, and 20th. In the tenth month (October) the temperature of the air was at no time above yf, but varied between that and 490 irregularly; the mean temperature was 620; the latter part of this month we frequently had white frofts at night; it rained on the 10th, 20th, arid 31ft. • EPIDEMIC YELLOW FEVER. 3 Mufquetoes were never before known, by the old- eft inhabitants, to have been So mimerous as at this SeaSon, eSpecially in the South-eaftern part of the city ; they were particularly troublefome to foreign- ers, many of whom, had thofe parts of their bodies that were expofed to them, covered with bliflers from their venomous operations. Our fummer fruits in general were no ways extra- ordinary ; water-melons particularly, from the wet- nefs of the feafon, were very flafhy and infipid. It was remarked that many laborers employed at the different buildings, gave out at their work, from the exceffive heat of the weather. An unufual number of perfons fufFered in the warm part of the feventh and eighth months, from drinking cold water; and feveral fell down and died in the ftreets, whofe deaths were afligned to that caufe, when it more probably was induced by an apo- plexy, brought on by the exceffive heat of the fun; one cafe came under my particular obfervation which was certainly of that kind, although currently report- ed otherwife. The cholera infantum, was very common in the early part of the fixth month, and increased as the weather became warmer. Bilious cholics and ch'[ea- teries became very prevalent in xhe feventh and eighth months. At this time alfo the cholera morbus carried off a number of grown perfons. In the beginning of the ninth n:o;:th, the meases made their appearance, but they Suddenly vanifhed with the above mentioned dileaiej, as Soon :u the yellow fever had Spread itfelf among us: I did not AN ACCOUNT OF Til! obferve but a fingle cafe of it during the dominion of this powerful epidemic. The common remitting bilious fever, was no ways uncommon in the fummer months, but this alio gave way, or rather perhaps, run into the yelloiv fever, as that gained ground in the city. As early as the fixth of the feventh ?nonth, I was called upon in conjunction with Dr. Treat, then health-officer to our port, to vifit Thomas Fofler, a patient brought into the alms-houfe, whom we found affected with all the full marked and decided fyrnptoms of an highly malignant yellow fever; the adnata of his eyes and his fkin were of a bright yel- low, the latter covered with purple fpots, his mind deranged, his tongue covered with a dry black for- des, with hemorrhages from his gums and nofe, and a difcharge of black and very offenfive matter from his Stomach and bowels; he died on the ninth. Dr. Treat was taken on the 2 2d of the J"eventk month, and died on the 30th. Several other un- doubted cafes occurred, about this time, in the neigh- borhood of Dover-ftreet, but the firft one that came under my particular obfervation, was that of James Daiton on the 12th of the eighth month, then in the fitth day of his illnefs, of which he died the day fol- lowing as yellow as gold. From this time the dif* eafe became more and more frequent; yet as we find by the accurate accounts of the Health Committee*. not above two a day upon an average died of it, till the 24th of the month. The increafing prevalence of the epidemic at the upper part ofWater-ftreet and in Cherry-ftreet, and in ail the neighboring low ground between them ; in! Chatham and the lower part of George-ftreets, in EPIDEMIC YELLOW FEVER* 5 the forepart of the ninth month, became fo alarming as to drive many of the moft opulent of their inhabit- ants to the country, while the lefs prudent and the more indigent remained expofed to a difeafe, which, from this limited fpot, in lefs than three months, car- ried as many as fivehundred to their graves. The difeafe was not, however, confined entirely to this part oS the city ; for in every other fituation, favoring the accumulation of filth and ftagnation of putrefactive materials, there it was no Stranger : it raged with peculiar violence in the vicinity of a moft intolerable pent up fink, to the weft of Peck-flip, which is the receptacle for all the refufe kitchen arti- cles, and yard wafli of a number of lots fronting Pearl and Water-ftreets, that back upon it; it was like- wife very prevalent in the neighborhood of the Fly- market, alfo in and about Skinner-ftreet, as well as in fome of the unregulated grounds on the north fide of the town. If an account of the epidemic, as it pervaded the different parts of the town, could be accurately as- certained, and depicted in colors, heightened in pro- portion to the combined early time of attack, and the numbers affected, blazoned by its comparative ma- lignity, there can be no manner of doubt, but that the low ground in the foutheaft of the city as above mentioned, would appear as the grand center of the .. calamity, diffufing its effects, like diverging rays, to the adjacent parts ; aiding by its moft powerful influ- ence, different fecondary centers, already fmoking hot, to flame out its peftiferous operations. The ma- ny folitary cafes of the difeafe that have occurred in diftant healthy Situations, appear to have been kin- dled up by imprudent individual expofures too near thefe fources of infection. 6 AN ACCOUNT OF T.i' The black people appeared to be as fuhject to the dieafe as the -whites, but it was not fo fatal to them ; I of eight that I prefcribed for, only one died, and with 1 her, the complaint having ftclen in under the deceit- J ful form of a common cynanche, was permitted to run on for fome days, before medical aid was called for. By report of Dr. S. L. Mitchell, in behalf of a com- •. mittee of the Manumitting Society of this city, it ap- pears that not a fingle fcholar of the free black School, under their patronage, died with it. Sever?! circumiiances tended to render the difeafe particularly fatal to the more indigent part of the community: ift. The higher prices of houfe-rent in the other parts of the city, having concentered a great proportion of them in the epidemic neighborhood, and crouded them in very fmall confined apart- i ments; a number of houfes contained as many fa-1 milies as it had rooms in it. 2d. Their poverty not v| permitting them to quit their place of refidence when fl the dileaie came around them. 3d. T he great difficul- ^ ty cf getting nurfes, and their exorbitant prices pre- M venting them from getting proper attendance before m their Situation became known to the Committee of M Health, often-times a whole family being taken down fl about the fame time,' their panic ftruck fur-day jfl friends cuitting them in their diftrefs, from the fear J cf infection. 41b. The neglect cf obtaining early! medical afliftancc, from a hope that their difeafe was«« not the prevailing ere : and 5th. The refufal of ma-1 ny, after they were taken ill, thus miferably Situated,-M to go to Belle Vue, " left (to ufe their own expreflion) | they fhould catch the Yellow-Fever and die." : ,. Forcirne'.' who came from a more temperate cli- " mate, as the Engl ift!, Irifh, Scotch, &c. and people from the country, who had not long refided in town, : were particularly obnoxious to this complaint. cPlD.^MIC YELLOW FEVER. 7 The French from the Weft-Indies, feemed proof a i-ainft the influence of this epidemic, a numerous family of them continued in the midft of it, and view- ed without danger the death of a great many, and the difeafe of nearly all their neighbors who remain- ed in town; not one of them fuffered the leaft in- difpofition : In another boarding houfe of them, con- taining at leaft thirty or forty perfons, not far from Peck-flip, not any of thern took the complaint, al- though numbers of the other inhabitants were drop- ing away with it, on every fids of them. The difeafe Spared no age or Sex, although it was mod fatal to the young and thofe in the prime of life. Symptoms of the difeafe, as exhibited in the different parts andfundions of the body. ift. The vital fund ions Suffered extremely in the tirfl attack of the difeafe, it generally coming on with chillnefs, an anxious and interrupted refpiration, with a total abfence of perfpiraiion ; this however, in fome inftances, came on very copiouflv, after the great heat that generally followed the chill, had exifted for a rime, but in moft cafes the fl^in continued dry and parched, except a fweat was induced by artificial means. The pulfe was as variable as the hues of the ca- meleon; in moft cafes it was frequent, and after the chill had fubfided, it became Somewhat hard: vet in- ftances occurred of a preternatural flownefs. 1 me-. with one cafe in a black man, where it beat only for- ty-two ftrokes in a minute; and in another perfon there was a complete intermiflion of k in every twelfth or fifteenth puliation : and in other patient.?, f t> AN ACCOUNT OF THE particularly in the 3d or 4th day of their complain!.;-., were phyficians to judge from the pulfe alone, the, would declare them in a convalefcent ftate, at the very time they wrere in the moft imminent danger and Sometimes within a few hours of their end. Al- though I firmly believe with my moft eminent teach- er Dr. Rufh, that the pulfe is our bcft guide in the knowledge of difeafes, yet in no complaint that has ever occurred to my observation, have I found this moft fure index of the ftate of the fyftem, fo little to be depended on. Hemorrhages from the nofe, gums, flomach, uterus, &c. were very common at the com- mencement, as well as in the'more advanced peri- ods of this difeafe. 2d. In the animal functions this difeafe in its firft attack, produced laffitude, and an averfion to all kind of bodily exertion with a fenfe of general debil- ity, attended with violent pains in the head and back, femetimes Shooting down the le^s : thefe fre- quently preceded the chills, and in moft cafes ac- companied it and continued afterwards, as a very diftrefiing Symptom of the diSeaSe. The mind was oftentimes very much dejeded, with imperfed vifion and memory, "followed by delirium,] ubfultus, tendinum, he. before death. * There was in many cafes an evident, though flight, remiflion in the violence of thefe Symptoms Some- times in the courSe of twenty-four hours'from the time of the attack, as alfo at fome other periods ; but in the hurry of the raging epidemic, I was unavoidably prevented from gaining an accurate knowledge of them. 3d. No part of the body appeared to Suffer more than the natural functions, which includes the alimentary canal and fecretions. The flomach, as in EPIDEMIC YELLOW FEVER. 9 all fevers, was affected with a degree.of naufea, and Sometimes vomiting at the firft acceffion of this ail- eafe, which frequently fubfided for a while, but is fucceeded about the third day, if propev means eye not ufed to prevent it, by an almoft unconquerable irrita- bility and retrograde movement of this organ, throw- ing up large quantities of green or yellow bile, and re- jecting immediately every particle of medicine, feed or dr'nkt that was taken into it—afterwards discharging an aquccus fluid containing a number of light dun co- lored fpecks in it ; this, if not checked, was followed by a puking of a fluid exactly refembling coffee, with its grounds floating in it, which by (landing, would fettle to the bottom.. The vomiting which occurs about the third day* frequently, is the only diftrefling fymptom that the patient labors under, his pulfe becoming natural, fkin cool and moid, with an entire freedom from pain, and a perfect clearnefs in the mental opera- tions, that infuperable circumftance Handing alone, as it were, to humble the pride of phyfic, and to warn, in cool blood, the unhappy fufferer of his precarious existence. A hiccoughing often was very troublefome in the dif- ferent ftages of this complaint. The bowels were very uniformly and obstinately cofiive: there were fome ca, fes it is true, that were attended with frequent evacu- ations, but thefe generally feemed rather of a partial dyfentery nature, and not free difcharges from the whole courfe of the inteftines. The fecretion of bile was greatly increafed, as ap- peared t>y its copious difcharge from the ftomach in vomiting, as well as from the bowels when excited by proper purgatives. The flow of faliva and excre- tions from the mouth and fauces were not much i:n- iO AN ACCOUNT OF THE peded ; in the beginning the icngue appearing meifr and a little while, after a few days it became more thickly furred and affumed a deeper hue, but fre- quently in the latter Stages it became quite dry and coveied with a black crufL The appearances on the [upcrfalcs were various, the fr.'ni oftentimes retained its natural appearance,, but frequently, though not uniformly, as the difeafe advanced, it affumed a yellow tinge. Mufquetce 1 hc-3, which before had entirely disappeared, fhewed them- Sclves in all the parts that had been expofed to them, in fmail purpleifli red fpots ; thefe were often taken for petechia, which Sometimes, but more rarely ap- peared. Unfeemly fcabs, oftentimes in the latter ftages, formed about the mouth, which, on being Scratched- off, Srequently were Sollowed by troubleSome little. hemorrhages. Thefe eruptions did not in this fever as it docs in others, indicate any favorable event of the complaint. The adnata of the eyes, in the beginning where the attack was fevere, generally were tinged and fuffuSed with a reddilh color,changing with, the Skin to a yel- low, as the difeafe advanced : there were many, how- ever, even among thofe who died, whofe fkin nor eyes fhewed the leaft appearance of tins color. DIAGNOSIS. If it fhould be eftablifhed, that this fever is as highly contagious as is„ perhaps, too generally believed, its diagnosis or peculiar fyrnptoms diftinguifhing it from others, would become a matter of the greatefl im- portance, both to individual Safety and to the wek fare of the community at large. EPIDEMIC YELLOW FEVER. II This part of the Study of medicine has, of late, been confidered of lefs confequence than formerly, fmce the fallacy and imprudence of prefcribing for the name of a difeafe, has been fo fully expofed and juftly condemned by the generality of phyficians ;— however, in this particular complaint, as the hopes of a cure depend, almoft entirely, upon the means ufed in the firft two or three days of its attack, it certairdy muft be cf prime neceflity to know it in its early ftage. We cannot be too careful in detecting the existence of this difeafe, for in its commence- ment, its evident Symptoms are oftentimes no way in proportion to the danger. Hence, as Dr. Jackfon obferves, (in hitreatife on the fevers of Jamaica) " perfons unacquainted with the nature of the difeafe, " would be difpofed to believe that the patient ex- " preffed Sufferings that were not real." And hence phyficians are Sometimes led to neglect them till it is too late to Save their patient:. In the firft ftage cS this Sever it is oftentimes with difficulty diftinguifhed from the common bilious re- mittent, its fyrnptoms in general being exactly fimi- iar, only aggravated in degree ; the pain in the head and back are more fevere and conftant, and the re- rnimons, whenever they are obServable, are more obScure : ThoSe who are well acquainted with the difeafe, may oSten recognize it by a certain undef- cribeable appearance in the countenance oS the Sick, the eye is often more red, and the face more flufhed than the heat of the body and the general action of the fanguiferous fyftem, would lead us to expect. The remarkable irritability of the Stomach, that generally comes on (when the difeafe is permitted to run an uninterrupted courfe) about the third or jkh rth day, whereby a conftant naufea and retchings 12 AN' ACCOUNT OF THE to vomit, immediately brings up every thing#as Soon as Swallowed, Seems to be a pretty diflinguifliing mark of this difeafe at this Stacc of it. o The yeiJow fkin, and coffee ground or bhcb vomit- ings, as they Sometimes occur in the more r.cvanced Stage, maybe looked upon as derided art unequivo- cal evidences of this complaint; but they cannot be- confidered as pathognomic fyrnptoms, for although they are to be found in this fever only, yet in the great- eft proportion of cafes they do not attend it. The prevailing epidemic fhould always have a great influence in fixing our judgment with refpect to this, as well as other difeaSes. Whenever it is found, from decided caSes, that it really exifts in any particular Situation, I fhould confider every fever, in that neigh- borhood, attended with aggravated fyrnptoms of a common bilious remittent, to be of this kind ; for I mould fuppofe the powerful operation of its caufer would certainly predominate over the milder eaufes* of more moderate maladies. PROGNOSIS. The prognofis is to be drawn from the diSpofitioi; and conftitution of the perfons affected, as well as from the particular fyrnptoms. Thofe who had been much debilitated by previous difeafe, great anxiety of inind, drunkennefs, &c. moSt generally admitted of but an unfavorable profpect as to the event of this ciifeafe, as likewife did the refolute and hardy, who would not early fubmit to their complaints, but en- v deavored to Shake them off as they would a common rr.tarrh. I ufed to warn fuch ones at my firft vifits, that I feared from their difpofitions, that they would undertake to wreftle with their difeafe, and that if they did they would furely fall under it, and unfor* EPIDEMIC YELLOW FEVER. 13 tunr.'.ely their conduct too often verified my frars and justified my prognostic. In the early Stages of the complaint, ii it came on very moderately, without much affection of the head, if the eyes and countenance were not much affected, and the bowels were eafily moved by the medicines hereafter to be mentioned, Ave, in general, were war- ranted in pronouncing a favorable termination. But when the face and eyes were fuSiufed wi 5 67 6 68 7 S 68 50 9 71 50 IO 11 75 12 77 5° *s 70 50 »4 71 '5 72 50 j6 73 5° 17 74 18 74 »9 79 7.0 / / 2 [ 77 22 76 23 74 5° *+ 73 25 7^ 26 7 1 27 70 50 28 <>9 75 29 73 30 88 74 ( T 74 73 6) 50 78 50 66 73 S S E S E E N E S E S NE N N S E s \v s \v sw u * F. s i :." e S E N NE K E Si r s s \v S E W s s \v w Obfervations on the weather. A. M. P. M. louch do.' rain cloud) clear do. ihund. ;lear do. i>ht. i-ar do. do. do. do. do. do. cloudv clear do. do. cloudy Co. rain •loudy do. do. clear do. do. It. wind do. It. wind &liglit. hi. wind and rain It. wind wind ram vhid th.&lig. cloudy It. wind ck*ar rain It. wind EPIDEMIC YELLOW FEVER. 29 METEOROLOGICAL OBSERVATIONS, MADE IN THE CITY OF NEW-YORK, IN 1795. Eighth Month (Auguil) Days j Thermo ncvr obd; rved at 1 Prevailing Obferv'.tions on of the 1 8 A. M. I P. M. 6 P. M. winds. the weather. Month.' deg. him. deg. hun. deg. hun. 8. 1. 6. 8. r- 1 73 25 80 77 5° w S £ S W cloudy 2 79 5o 86 78 s w 1 clear 3 73 71 50 74 E SE 1 ftorm & rain 4 77 82 80 w NWJ cloudy It. wind 5 80 88 50 83- w s v.r cleat- 6 80 89 50 86 V.' do. 7 82 93 5° 84 w do. 8 82 75 87 78 w SE w do. 9 79 87 82 50 s s w| 1 p-t.rain. 1 t 10 80 50 87 78 w ; \v: clear rain 11 IS 79 76 N E sE s cloudy It. wind 12 74 80 75 NW SE rain •3 69 75 5° 75 N CO. [4 69 7i 75 72 50 N £ s w cloudy '5 71 73 5° 73 n 1? s w clear 16 69 73 77 S VJ w do. 17 75 85 50 76 N W s w do. 18 79 50 M 50 82 50 s w N W w do. It. \n«d l9 77 86 82 w do. 20 79 5o 88 63 w N do. rain 21 57 50 60 50 59 N N E raia it. wind 22 61 50 66 67 50 N E i cloud v do. 23 66 50 68 50 68 N E 1 i K E d".' rain 24 69 71 70 E -> k do. ^5 73 8v 77 SE S V» clear It. wind 26 76 84 77 N S SE do. calm 27 75 81 74 SE s SE do. 23 72 79 76 S do. 29 73 75 82 80 50 S cloudy 30 76 85 79 i do. clear 31 73 75 74 72 S clear rain 3© AN ACCOUNT OF THE METEOROLOGICAL OBSERVATIONS, MADE IN THE CITY OF NEW-YORK, IN 1795. Ninth Month (September) Days Thcrmcmcter obfcrved at Prevailing Obfervaticns en of the g A. M. I P. M. 6 P. M. winds the weather. Month deg. hun. deg. hun. deg. hun. 8. 1. 6. A. M. P. M. I 73 75 1 77 w N 1 cloudy It. wind 2 66 70 70 NE rain high do. 3 65 71 71 W clear 4 64 75 73 N W do. 5 67 74 5° 72 N W cloud) 6 70 75 73 N W clear 7 68 50 74 N N E rain 8 71 50 78 77 S S W 1 cloudy It. wind 9 75 83 50 77 s w clear ' 10 75 82 76 s w do. 11 74 84 50 79 s w w N' \V do. 12 63 70 67 N N E E do. '3 68 66 70 sr. S cloudy rain H 72 50 81 80 s do. 15 75 50 85 50 82 50 s w S do. clear 16 76 87 8.3 s w do. do. '7 68 50 79 75 78 50 N E do. do. 18 ^7 78 -6 S clear It. wind '9 60 65 50 64 N N W rain 20 60 68 50 68 W s* clear rain 21 53 5o 61 57 N\V do. hi. wind 22 ' 48 58 57 N N V do. do. 23 53 68 66 W do. light do. 24. 57 66 50 64 W S W S do. high dc. 25 53 73 "2 s w do. i6 62 50 72 *5 ? V. S E SE cloudy 27 66 68 75 (>1 E SE do. 28 66 73 2S 68 50 s clear It. wind 29 63 50 64 25 60 NW cloudy 3° 5° 58 75 r,0 N ! clear It. wind EPIDEMIC YELLOW FEVER. METEOROLOGICAL OBSERVATIONS, MADE IN THE CITY OF NEW-YORK, IN 1795* Tenth Month (October) Days Thermometer obferved at Prevailing Obfervations on of the 8 A. M. I P M. 6 P M. winds the weather Month deg. hun. deg hun. deg. hun 8. 1 6. A. M. P. M. I 56 70 66 i W N E s clear ic. wind 2 57 61 50 60 N E j E cloud / 3 55 5° 63 50 62 E SE clear 4 65 5° 72 50 67 75 S sE do. 5 65 75 69 s SE cloudy 6 6z 67 50 66 w ■S \\ clear 7 57 50 67 65 w s w cloudy rain 8 54 54 55 NW do. 9 5i 62 50 61 NW w clear 10 48 50 63 61 W s cloudy rain 11 60 69 65 NW.' W do. 12 55 5° 66 66 W j do. It. wind *3 60 7i 66 s sw do. do. *4 61 68 68 s w do. 15 65 66 7i s do. dif.thu. 16 52 50 . 62 60 w clear It. wind 17 58 , 49 52 s w w cloudy high do 18 42 54 5° w s w w clear *9 38 50 49 5° 49 5° w s do. 20 55 62 50 55 50 s NW rain 21 46 52 50 53 25 N NE clear 22 44 5o 53 5o 55 NT E s E cloudy c. wind 23 55 61 59 5° N E rain 24 52 5° 63\5° 58 50 NW W clear 25 47 57 57 W do. 26 47 54 5° 55 w N do. It. wind 27 43 58 5o 54 N s w do. do. 28 49 60 50 60 s w W do. 29 52 70 66 w dp. 3° j 55 69 61 w s do. 3'i 52 50 55 54 5° s w f°ggy rain F 32 AN ACCOUNT OF THE The Caufe of the Fever, and the mofl probable method I of preventing its return: likewife, the Precautions to be nfed to avoid an Attack, if it fhould again become j Epidemic. On the fixth of Auguft, 1795, I received a note from John Broome, Chairman of the Committee of Health, " earneftly foliciting me to give them every " aid in my power, by my prudent advice, &c. for " the accomplishment of the important end of their " inftitution." In confequence of which, a few ( days after, I made him the following communica- tion. ' That a malignant fever exifts among us, is a me- ' lancholy certainty, well-known to the Committee ' of Health; that this fever, in itfelf, is of a danger- ' ous nature, there can be no doubt; but whether it ' is contagious or not, is a queftion yet undetermin- £ ed. I have not known or heard of a fingle well c attefted proof, of any perlon taking the complaint ' from another that was affected with it. \ i My advice is, that the Committee, while they * continue their unremitted and benevolent exertions, ■ 1 in preventing the introduction of infectious difeafes ' from abroad, fettle not in afalfe fecurity, and neg- ' lect the caufes of difeafes that may, exift in the ci- j ' ty. It is from the unguarded operations of thefe \ ' inwalled enemies, that. I conceive we have to appre- j 4 hend the greateft danger. \ If I have been rightly informed, a great propor- J < tion of the perfons, that have at this feafon been | ' affected with fevers of a fufpicious nature, has been EPIDEMIC YELLOW FEVER. 33 ' confined to thofe whofe refidence or occupation ' has obliged them to pafs a confiderable part of their ' time between Peck-flip and the New-flip. If fo, it c certainly is a matter of confequence, to know, whe- c ther in this part of the city, there is not fome local ' caufe that may induce fo fatal a malady. ' That putr'fying fubftances, after a continuation 6 of very warm weather, will give rife to fuch com- c plaints; the fatal operation of the dock mud de- 6 pofited at Peck-flip in 1791, the putrid coffee in c Philadelphia in 1793, and the noxious exhalations ' from the creek in New-Haven in 1794, fufficiently ' prove, without the aid of many other equally cer- 4 tain, though more remote facts, that might be ad- ' duced in its fupport if neceffary. ' On thefe principles I have been led to fearch into 4 this part of the town, for the caufe of the prefent 6 complaint, and J believe my inquiries have not been 1 in vain: I fufpect that I have difcovered a fruitful ' matrix generating the feeds of this complaint, and 1 which if not properly cared for, may poffibly fpr^ad ' mortality in its vicinity. ' A few years ago the Corporation have had Wa- c ter-ftreet, between the two beforementioned flips, i filled up, without obliging the proprietors of the c property on the north fide of the itreet and in e Cherry-ftreet, to fill up their yards even to a level ' with it. Hence, the refufe water and offal fub- ' fiances, from the families occupying thefe places, 6 are left to flagnate and putrify; and what renders 6 it particularly diftreffing, is, that the healthful fhow- 4 ers, that in general wafh away all fuch matters from ' other places, here only tend to render them more ' active 5 for by the water not runing off, it diffolves 34 AN ACCOUNT OF THE ' and prepares them, thus pent up, for entering into ' their peftilential fermentation. Our regular and 6 heavy rains, perhaps have been one great remote 6 caufe of the frequency of thefe diftrefling difeafes, 1 in this neighborhood at this feafon. 6 It may be worthy of remark, that many of thefe e tenements contain feveral families; hence an addi- < tional caufe for putrefactive materials. * I make no apology for giving thefe hints to the ' Committee; the impreffion of their importance on 6 my mind, rendering it a duty: the hurry of an ear- 6 ly communication, amidfl frequent profeflional in- * teruptions, muft anfwer for their incorrectnefs." 6 With a fenfe of refpect and efteem, * I remain thy friend and fellow-citizen, 'VALENTINE SEAMAN-' New-York, 8th month 7 tAuguft) 17th, 1795. J The caufe of the difeafe as above fuggefted, not be- ing removed, its effects, in full fupport of myappre- henfions, truly " fpread great mortality in the \ici- " nity,'"' as is feenby its hiftory in the foregoing ob- fervations. This early idea of the origin of the epidemic, con- ftantly gained confirmation from the manner in which it increafed: it appeared to be almoft entirely confined to the level fouth-eaftern part of the town, and there it was the moft general and fatal, in the particular fituations that moftly abounded with thefe EPIDEMIC YELLOW FEVER. $$ pools of putrefactive exhalations. Thus it firft be- came the moft general in and about the lower end of Dover-ftreet: this is what might reafonably be looked for when we confider that befides all the lots fronting this ftreet being funk beneath the common level of it, there are alfo on the docks at its lower end feveral flore-houfes and granaries, built partly over the water on piles, without having the fpace under them filled up; the foundation of fome of them, on the fides fronting the water are partitioned up fo as to prevent the free circulation of the tide from warning away any thing from under them; however, theie partitions were not fo tight but that they let in water fufficient to favor the fermentation of the putrefactive materials that fuch a common receptacle will always collect, not only from exterior fources, but alio from the mowers of grain that frequently would pour down through holes that the rats fometimes would gnaw in the floor. Hence there can be no wonder, that the feeds of this difeafe mould ripen in fuch a hot bed of putrefaction, aided by the effluvia emited from the great flats of mud in the feveral furrounding impaired docks, left bare during the ree'efs of every tide. It is remarkable that feveral perfons employed in a large grain ftore-houfe, thus fituated over fuch afource of noxious miafmata, were among the firft victims of this difeafe. The difeafe foon increafed; numbers were taken in every part of that quarter of the town, lying be- tween the upper part of Water, Pearl and Chatham- ftreets, and acrofs to the lower part of George-ftreet. From an attention to the fubjec"t not only during the hurry of the epidemic, but alfo fince its extinction, I am led to believe according to my beft judg- ment, that four fifths of all the lots in this af- fected part of the city, were fituated below the level 3.5 AN ACCOUNT OF THE of the ftreets they fronted, whence from our regular rains, thev very generally became ftagnant, putrid mud puddles. I can hardly think it poffible, was it ■ not for the obftruction of the houfes preventing^ free obfervation of thefe grounds, that any candid I perfon acquainted with the common caufes of fevers, .1 could harbor the leaft doubt after walking through 1 this part of the town, but that the epidemic originated from this fource, rendered active by the con- tinued exceffive heat of the fun during the laft fum- t:er. It raged with peculiar violence in the parts that were near the docks; this is what might m be expected from the additional vapor of the I dock mud as above-mentioned. It alfo was very fa- tal in a part of George-ftreet, " not lefs than fixty " cerfons were buried out of it within the fmall com- " pafs-of twenty houfes." This was probably owing j to the poiionous fleams difcharged from large quan- tities of ftreet dirt and manure, collected during the fummer and depofitcd near the head of it, fubjoined to the common caufes above-mentioned. Its fatality to the Weft of Peck-Hip was induced, no doubt, by j the noxious vapors from the putrid fink there. The reafon of its prevalence about the Fly-market, can feem no v/ays iiraiige to any one acquainted with the [ fituation of that place, the market being built over an ofiennve fewer, whofe exhalations were confined , only by an imperfect hoard floor, to which may be added, the effluvia conftantly arifing from the putre- fying animal and vegetable matter all around, as well as from the flip that puts in at it. Skinner-ftreet is . I >\vly fituated, unpaved and very imperfectly drain- ed. That putrefactive tfiluvia will give rife to,and are the cc.mnv.n caufe cf fuch difeafes, is clearly proved by the accurate obflmuions of the moft judicious wri- EPIDEMIC YELLOW FEVER. 37 ters on the difeafes of hot climates. Lind's valuable book of interefting facts (Effay on the Difeafes of hot climates) abounds with proofs of this difeafe be- ing caufed by the air from the low lands in the Well Indies; he particularly mentions, that it often raged in the Greenwich Hofpital at Jamaica; which, as he obferves, was unfortunately built near a marfh, and that it could not proceed from any fource of infec- tion in the hofpital. Dr. Hunter fays (Difeafes of" the army in Jamaica) fhips lying at Port Royal in Jamaica, on moving and taking their ftation higher up the harbor, have in a few days become fickly. " The men, fays he, have been feized with fever;; " owing to the low fwampy lands along fhore, and " at the head of the harbor, from which laft the er.- " halations are carried every morning towards the " fhips, when the regular fea breeze fets in, as is " perceived by the bad fmell which accompanies it." He fays that there are examples, where cut cf fixtv or feventy men, employed in filling the water cafes, not one has efcaped a fever, from the watering place being wet and fwampy. The fame author obferves, that Fort Augufta, which was at other times a falubri- ous fituation, became fickly in 1783, the fea that year having rifen higher than ufual, fo that it " overflowed the whole of the ground on which the " fort ftands, near a foot above the furface in fome " places, and on ebbing left much flime and ouze. " A few days after this, many of the men were taken " with fevers." Dr. Jackfon (Treatife on the Dif- eafes of Jamaica) as well as a hoft of other author.?, might be brought if neceffary, to prove that putrid exhalations are the common caufes of epidemics. The above facts, together with the many others ad- duced by Dr. Rufh (Account of the Yellow Fever &c.) in their fupport, appear to me to be fufficient 38 AN ACCOUNT OF THE to eftablifh that opinion with every unprejudiced per- fon—which if allowed, no one acquainted with the iituation of the part of this city where the yellow fever raged as above ftated, can have the leaft doubt but that it was owing to like caufes, without the ne- ceflity of ranfacking Weft India veffels or innocent bags of cotton, for that which is within ourfelves, and whofe veiy. effence perhaps, is fuch as proves it not to be of a tranfportabte nature*. Many of the ftrenuous fupporters of the conta- gious nature of this difeafe, compelled by the force of the foregoing circumftances, acknowledge, that the .difeafe may be caufed by other means, however they cannot entirely, give up this favorite opinion, but perfift in aflferting that contagion often does in- duce the difeafe, v.hen the foregoing ftate of the tur favors its operations; and they defy any one to prove that it does not. To prove a negative is al- ways difficult, fuch a one, perhaps impoftible. But fince the only proof we can have of the exiftence of a caufe, is the neceflity of it for producing known effects, and lince we are to admit, (according to Newton's firft philofophic precept) no more caufes than are fufficient to explain the appearances, and, as h:>s Ken obferved, (IVmberton's view of Newton's piiilofophy) " When one caufe is fufficient, if there '■'■ really fhould in nature, be two, which is in the cc Jail degree improbable, we can have no poffible ': means of knowiug it, and confequently ought not " to take the liberty of imaginine. that there are '* It has been obferved by Dr. Ruth, in Vol. I. of his Med. Ob- frrv.uions, as well as by Dr. Li-id, that mufquetoes generally attend a iic'.f'y feafon—the fame was obferved here during the lait fu:n::!.'.: the c~i:!e is very cl-.a--, for circumftances favoring the ni; of putrid -..uf.ruta, tnuully favor the generation of thefe in- EPIDEMIC YELLOW FEVLR. 39 " more than one." Now, therefore, as the above fuggefted caufe of our epidemic feems fully fufficient of itfelf to produce it, nothing can be more unphilo- fophic or imprudent than to fuppofr, that contagion ever jiad any thing to do with it. The moft probable means of preventing a like ca- lamity in future will be—ift, To have all the lots, particularly in the low parts of the town, filled up, fo as to afford a fufficient defcent to carry off the water into the ftreets, and not permit any of it to ftagnate in them. 2d, To have the dirt and filth in the ftreets and yards more carefully and frequently cleared away. 3d, To have the docks repaired and regu- lated in fuch a manner, as not to permit the mud to o-ather and be expofed to the fun at the ebb of the tide. 4th, To have the fpaces under the granaries and ftore- houfes on the docks, properly filled up or walled in. 5th, To prevent great quantities of ftreet-dirt and ma- nure from being collected in heaps, and left for any time on the vacant lots, in and about the city. 6th, To have the ftreets properly paved with a fufficient de- fcent to prevent any water from Handing in them; and 7th, To have the common fewers, in good or- der and well covered. An attention to thefe cir- cumftances, no doubt, will prevent the return of a like epidemic in this city; for, as I fuggefted fome time fince to the corporation, " whether the difeafe " is contagious., or whether it was imported or " not; this one fact feems to be pretty firmly eftab- " lifhed, that it never has fpread, but by the influence " of putrefactive effluvia." If, either from a neglect of the foregoing precau- tions or from any other caufes, the yellow fever mould again become prevalent in any part of this G' 40 AN ACCOUNT OF THE city, it certainly would be moft prudent for fuch I as have it in their power, to remove from it; or if unavoidable circumftances, or the calls of humanity \ fhould render it neceffary for fome to continue there for a part of the time, let them if poffible, fhun the night air, as the harbinger of death, and efpecially to avoid fleeping in that neighborhood, as they value their lives; for perhaps in the relaxed hours of reft, the epidemic miafmata may act with redoubled force, jj Dr. Lind's- inftances clearly fhews the particular dan- ger of fleeping within the limits of the contaminated - air ; many perfons having been taken with the com- plaint, after having flept a night on fhore in the low j] ground, while others, who had paffed a confiderable time there during the day, and always returned to the veffels at night, generally efcaped it. Befides, keeping from the night air of the epide- ! mic neighborhood, and the fleeping in a healthy part of the town: all perfons who are forced to pafs fome ^ of their time in the contaminated atmofphere, fhould 1 avoid with the moft fcrupulous attention, exceffes of J every kind; not only of eating and drinking, but 1 alio of heat, exercife and watching. But I wifh to a be underftood, not to mean a rigid abftinence from, 1 or a reflriction with refpect to thefe things ; but only to advife moderation and regularity in the ufe of ■ them, becaufe it is likely that a very low diet and the' ;fl entire neglect of wine, with them who have been ac- cuilomed to it, as well as cold, inactivity, too much J Jieop, fear, &c. may as effectually predifpofe to this ,'i complaint, as their oppofite extremes : I believe the 1 more regularly we fupport the natural healthy tone J of out bodies, the more powerful they will refift the m crudes of difeafes applied to them. 1 EPIDEMIC YELLOW FEVE- 41 The obfervation of Dr. Lining muft be a great fa- tisfaction to thofe who have once fuffered with this difeafe. He fays (Effays and Obfervations, Phyncr.l and Literary, vol. 2.) " It is a great happinefs that " our conftitutions undergo fuch alterations in it, as " forever afterwards fecures us from a fecond at- " tack." He certainly had a good opportunity of knowing whether it did or not, as it raged four times in Charleftown, South-Carolina (the place of his re- fidence) within fixteen years. In the Weft-India in- lands an attack of this difeafe, which feems almoft entirely confined to perfons from more.northern cli- mates, is called Tifeafoning, and after which, if the patient recovers, he is fuppofed to be pretty fecure. 1 never have known of any perfon having had it twice decidedly ; perhaps fome inftances fuppofed to have been that fever, were only common remittents. Dr. Rufh fays, (Medical Obfervations, Vol. 2.) that " during the prevalence of the meazles, he as well " as Dr. Quier, obferved feveral perfons (who had " had that difeafe, and who were clofely confined to " the rooms of perfons ill with it) to be affected witli " a flight cough, fore throat, and even fores in the " mouth." And what are called nurfe pocks, are no rare things with perfons (who have previoufly had the fmall pox) that have much to do with pati- ents in that difeafe : fo alfo is it poffible that fome people may fufter a flight indifpofition from the caufe of this difeafe, after having had it once, which per- haps ought not to be confidered as a full attack of it. It may be that the great debility, remaining after a complete removal of this difeafe, may predifpofe to an attack of fome other, perhaps of a fever of a dif- ferent nature, that might even prove fatal, fo like con- fequences might follow a fevere attack of the fmall pox and no one would confider this as a return of the difeafe. Notwithftanding thefe remarks are not en- 42 AN ACCOUNT OF THE tirdy conclusive with me, yet they have fo much in- fluenced me, in the opinion of the impoffibility of taking this difeafe more than once, that fhould it again become epidemic here, although I could not again venture among it with lefs hefitation than here- tofore, I certainly fhould with much lefs apprehenfion. METHOD of CURE. In the treatment of this, as of ail other difeafes, the firft object fhould be to remove their caufe ; for although in fome inftanees, the human body by habit may be enabled to refill the effects of injurious im- preffions, and even by proper means to recover itfelf after morbid effects are inducled, while the caufe ftill continues; yet that phyfician would be confidered very deficient, who would undertake to cure an oph- thalmia caufed by refiding in a fmoky apartment, or t]:e cholera infantum, originating from the impurity and heat of the city air, without firft advifing his pa- tients to remove from fuch an obnoxious fituation, fa- although he might fometimes fucceed in his at- tempts, yet it certainly would be attended with more difficulty and uncertainty ; fo alfo is it in the yellow fever ; hence in this difeafe it is of the higheft impor- tance to have the patient removed, as foon as poffible, out cf the reach cf the original caufe of his com- ehhits, lata a more falubrious atmofphere ; a neglect of this pi rhaps was one main reafon of the great frt.tlity of this epidemic ; therefor*, fhould it again prevail, it would be of the utmoft con'equence, for thofe whofe circumftances would admit of it, to fe- care a proper afyhim in cafe of an attack, and the poor ought to be induftrioufly fought after and ear- nciily advifed, early in their complaints, to remove lo fuch places as the police may prepare for their re- ccpti--11. V may be remarked, that but a finall pro* EPIDEMIC YELLOW FEVER. 43 portion died at Belle-vue who went there in the early ftages of their difeafes. Whether*the original caufe be removed or not, the next indications are, 1. To obviate the reftricted ftate of the bowels, and clear the alimentary canal of the fuper abundant bile that feems to attend the difeafe. 1. To ufe all means in our power to obtain a re- miffion of the fever; and 3. During the remiffion, to reftore the tone of the fyflem fo as to prevent a return. Whether the feat and throne of this difeafe is in the ftomach and bowels, according to Dr. Warren, or not, it muft be acknowledged that it is in a great degree upon a particular attention to them, that the hopes of a cure depend, as it is upon a particular morbid affection of them that the greateft danger is to be apprehended. To fulfil the firft indication, a fufficient dole, viz. ten or twelve grains of calomel, with as much jalap or rheubarb, fhould be exhibited immediately and repeated every fix or eight hours, till it purges freely ; its opeiatious fhould be favored by the plentiful drinking of warm chicken or barlev water or gruel, and keeping warm in bed; by theie means oftentimes a free perforation is brought on, and the fecond indication is accomplifhed at the fame time ; an almofl complete remiffion being the con- fiquencc. Let no one fear the largenefs of the dofe of the purgative, or its early repetit'en as above recom- mended, for in no difeafe perhaps is it of more con- iequence to obtain the fpeedy operation of medicine 44 AN ACCOUNT OF THE than in this; it is probable many Kves have been,. loft from the cautious timidity of Phyficians^in giv- ing but , fmall and repeated dofes of cathartics, till the difeafe ftole on to that ftage wherein the great irritability of the ftomach utterly refufed to retain any more of it, before they have given a fufficiency effectually to evacuate the inteftines. If a remiffion does not fucceed to the operation of this medicine, but fyrnptoms of great excitement,' with violent pain in the head, &c. particularly in perfons of a full habit of body, with a plenitude in the vafcular fyftem, bleeding undoubtedly promifed and proved of the moft effential fervice, and ought by no means to be neglected; but I do not wifh to be underftood to recommend the indifcriminate ufe of the lancet by any means, for there are innumera- ble circumftances, both as they relate to the previous ftate of the patient, as well as to the exifting fyrnp- toms, that fhould always govern the judicious phy- fician in the ufe »of this moft powerful remedy. After the operation of the purgative, if the degree of excitement or tone in the vafcular fyftem, fhould] not juftify the loofing of blood, or if as much has been drawn as the ftate of the patient may render advifeable, and ftill there remain a degree of tenfion; in the pulfe, a drynefs on the furface, &c. a fudorifici draught of half an ounce of fpt. minderer with twen- ty drops of find, thebaic has often been exhibited with the happiell effects; a fweat generally fucceed- ing with a confidcrable remiffion of all the fyrnptoms; in conjunction with the fudorific portion, the patient; fliould have his feet and legs fomented with flannels1 wrung out of warm water, for as long as half an hour at leaft; he fhould alfo favor its operation by a plen- tiful dilution with the beforsmentioned drinks. EPIDEMIC YELLOW FEVER. 45 The ufe of antimonial medicines, have been greatly recommended in this ftate of the difeafe, to bring on a remiffion; but I confefs, in the few inftances where- in 1 made trial of them, they did not anfwer mv ex- pectations, the ftate of the ilomach generally beino- fuch as would not bear even the fmalJeft dofes or* them. For the violent pain in the head attending this firft ftage, nothing feemed more effectual than the con- ftant application of linen cloths, wetted with cold vinegar and water to the forehead and temples, and changed as foon as they became warm. I know not whether Dr. Jackfon's method of ' ufing the warm and cold bath alternately, has been practifed by any phyficians of this city; but the dafh- ing of cold water over the body, and afterwards drink- ing plentifully of a ftrong infufion of rad.ferpentar. has been much cried up by fome; I ufed it in but a fingle cafe, and although the patient was particularly attended to, yet the looked for fweat and remiffion did not fucceed; this was neverthelefs, accomplifhed afterwards by the partial application of cold vinegar and water to his forehead. After the bowels were properly evacuated and a remiffion obtained, I loft not a moment's time, but immediately applied to the ufe of the bark, in dofes apportioned to the ftate of the ftomach,half a drachm, if it would retain fo much, was given every two hours, otherwife half that quantity was given and increafed as the ftomach would bear it; it was exhi- bited in milk and water or fome of the drinks before- mentioned, which ever was moft agreeable; a few- drops of the acid elix. vitriol with each dofe of the bark, fometimes would make it more agreeable to 46 AN ACCOUNT OF THE the ftomach; it feems hardly neceffary to mention that in this cafe it muft not be given in milk* When the bark in fubftance could not be retained, ' the cold infufion was fubftitutcd in dofes from half an ounce to an ounce, according to circumftances, J and repeated every two hours or oftener if it fat well on the ftomach. At the exacerbations of the fever, the ufe of thefe remedies was often fufpended, and the means beforementioned were applied to, till \ a degree of remiffion was again obtained, when the j ufe of the bark, &c. was again refumed. When the | patient was coftive, he had a few grains of rheubarb imited with each dofe of his bark, till that ftate was obviated. i The acid elix. vitr. was ufed with advantage : during the remiffion of this difeafe, particularly if hemorrhages attended it. I have already mentioned it, as ufeful in making the bark fit eafy on the fto- 1 mach ; but in cafe the bark fhould be retained well without it, it then would perhaps be better to admi- nifter it between the times of taking that medicine; it may be that this acid, while it covers the bitter tafte, may likewife tend to leffen the tonic effects of the bark. Generallv, if the abovementioned means were not ufed, and frequently notwithftanding our greateft at- tention, about the third or fourth day, the fecond flage of the difeafe would be ufhered in with pain and conftant ficknefs at ftomach, particularly upon fwallowing any thing; an epifpaftic was often ap- plied to the fcrobiculis cordis in this fituation, and fometimes with advantage; fome others received be- nefit from ufir.g warm fomentations tQ the part. Laudanum was rejected; but la fome inftances I thought a grain of folid opiar.i was administered EPIDEMIC YELLOW FEVER. 51 with good effects, and fmall bleedings feemed fome- times ufeful; this, however, as well as all other means, often failed, the ftomach throwing up every thing that was taken into it. In this defperate ftate, our laft refuge was to the bowels, and our only de- pendence appeared to be upon the plentiful exhibi- tion of our remedies per anum, half an ounce of pow- dered bark, with a gill of milk, chicken foup or beef tea, and twenty-five or thirty drops of lauda- num, make a proper injection for this purpofe; it fhould be repeated at leaft twice a day. This means no doubt has preferved the lives of many; fhould the bark be retained in the bowels till the period of ad- miniftering the third dofe, it would be advifeable to bring it away by a common injection of warm water, before that is given. From obferving that none died who were affected with a falivation, I attempted in feveral inftances to induce that affection, by rubbing the gums with calo- mel and ufing mercurial frictions; but as thefe at- tempts were made only in the latter flages of def- perate cafes, I never fucceeded. May not mercurial frictions be advantageoufly ufed from the commence- ment of the difeafe to produce this affection ? The diet of the patient in this difeafe, fhould be of the mildeft nature; panado, chicken foup, beef tea, roaft apples and milk, tapioca, &c. appeared to agree bell with the delicate fituation of the ftomach, and perhaps were the moft proper food that could be taken. In the convalefc'ence, a continuance of the bark and elixir of vitriol, a more nourifhing diet of roaft- ed oyfters, beef-fteakes, porter, &c. together with If 52 EPIDEMIC YELLOW FEVER, &C moderate exercife in the country air, were the mofl: effectual means of reftoring the loft tone to the de- j bilitated fyftems of thofe who happily furvived the effects of this moft dreadful difeafe. FINIS. LETTERS XO WILLIAM BUEL, Physician, ON THE FEVER WHICH PREVAILED IN NEW- YORK, IN 1795. BY E. H. SMITH. TO WHICH IS PREFIXED," AN ACCOUNT OF THE TEBRILE DISEASES 0>F SHEFFIEL3, (MASSACHUSETTS) IN THE YEARS I793, I794ANB I795. B T W. BUEL. "^'~' '.VfiTr / A N ACCOUNT OF THE FEBRILE DISORDERS WHICH PREVAILED IN SHEFFIELD, IN THE STATE OF MASSACHUSETTS, IN THE YEARS x793> 1794 and 1795. EXTRACTED TROM A LETTER OF WILLIAM BUEL, PHYSICIAN AT SHEFFIELD, TO E. H. SMITH, PHYSICIAN, OF NEW-YORK. J3EFORE entering directly on the fubject of the difordcrs, which prevailed here in 1793, 1794 and 1795, 1 fhall mention fome circumftances relative to the face of the country in the Town of Sheffield. The river Houfatonak runs in a ferpentine courfe through this town, from North to South. Upon the banks of the river, on each fide, is an extent of intervale, or meadow land, averaging on both fides at about a mile in breadth. The greateft part of this intervale is overflowed at the time of the thawing away of the fnow, in the fpring ; and fometimes, by large and hidden frefhets, at other feafons. The na- ture of the foil, in general, is fuch, that, veryJbon after the water is off, the land is dry and fit for tillage. It is, however, much interfperfed with coves and inarfhes ; in the former of which the water re- mains ftagnant a confiderable part of the fummer, and in many of them perpetually ; of the latter there are not many upon this river, but there are fome which remain fuch through the feafon. LETTER FROM DR. W. BUEL, Befide the Houfatonak, there are two other conn- derable ftreams, running through part of this town, which unite and empty into that river. Upon each of thefe ftreams are large tracts of low, marfhy lands; great part of which is overflowed by frefhets, and is never perfectly dry.—There is (which is very mate- rial) a mill-dam, on each of thefe ftreams ; and the*' two dams occafion the overflowing of feveral hund- red acres of the low lands. As fummer advances, and the ponds fall, confiderable parts of thefe lands are left uncovered by the water; more or lefs, ac- cording to the drought of the fummer. In both of thefe ponds are large quantities of timber and other vegetable matters, which, in hot weather, are al- ways in a ftate of putrefaction. This ftate exifts in an increafed degree as the fubftances become more expofed to the action of the fun. The fcetor occa- fioned by this putrifying mafs is fuch, in hot weather and when the water is low, as to be extremely offen- five to the fmell, at the diftance of many rods. The inhabitants of this town, who live in the vi- cinity of thefe marfhy and drowned lands, have, as would naturally be expected, been always fubject to remittent and intermittent fevers, from its firft fet- tlement. It is, however, generally remarked by the old people, that thefe diforders have of late years— until the three laft—decreafed : owing, probably, to the clearing, or partial draining, of the lands. Although the diforders which have prevailed in this town, for two or three years paft, are owing un- doubtedly, principally to thefe local caufes; yet it is not improbable that fome predifpofition to them dj was occafioned by a general conftitution of the air; To afcertain this point, with any degree of precifion, we ought to have before us an accurate hiftory of the TO DR. E. H. SMITH. 55 xveather, for feveral years paft. Even then it would, perhaps, be impoffible; as it has ever been found a difficult matter to trace any connection between the manifeft qualities of the air, and the effects of a ge- neral conftitution of it, favorable to difeafe. m As I am unable, either from minutes, or memory, to give any account of the weather, I fhall leave the mat- ter unattempted. In the year 1793, during the feafon in which fuch complaints ufually appear, intermittents and their concomitants were more frequent than they had been for many years before. In September and October, there were a few fcattering inftances of bilious fevers. Early in the fpring of 1794, inflammatory com- plaints, chiefly of the pneumonic kind, were unufu- ally prevalent. They were foon fucceeded by inter- mittents ; which were more frequent than they had been the year before. Nothing peculiar attended them ; and they continued to occur pretty often through the fummer. Towards the laft of July, the bilious, or, as it is called here, the pond-fever, began to make its ap- pearance ; principally about the South Pond, one of the mill-ponds beforementioned, and near the Canaan line. There were fome fcattered inftances about the North Pond : and a few, which were at fuch a dif- tance from both, that they were, probably, occafioned by the flagnant water about the great river, the Houfatonak.' But the diforder was chiefly confined to the vicinity of the South Pond. The influence of this pond appeared to extend about one mile and a half from its borders. Within this place there are ^ about 150 inhabitants j and about 80 of this number $t> LETTER FROM DR. W. BUEL, were affected wkh the fever : part of them inhabit- ants of Sheffield, and a part of Canaan. Among" thofe who were fick, there were five or fix milance^ ; of mortality. There were not more than ten or twelve perfons who had the diforder in other parts of this town. From thefe there was but one death ; and that in a cafe complicated with pregnancy, and' eventually with phthifis pulmonalis. People con- tinued to be attacked with this fever through the' \ months of Auguft, September and a part of October. The diforder was, probably, in all refpects, what | is termed a bilious remitting fever. It began with an ague fit; intenfe pains in the back, head and,' limbs, foon fucceeded by thirft, drynefs of the fkin, &c. continuing without much variation 18 or 20 =1 hours: a flight moifture then broke out upon the d fkin—feldom a profufe fweat; a degree of remiffion 1 of the fever, and abatement of the pains, then enfued, \ and continued till about the time of day of the firft attack, when another exacerbation of fever com- menced, with fyrnptoms fimilar to the firft. If the difeafe was left to itfelf, the remiffions would fome- times become fhorter and more imperfect, as the pa- roxyfms were repeated, until it grew to be nearly or quite a continued fever. A diarrhea, and fometimes dyfentei ic fyrnptoms were added to the reft. Moft of thofe who died were attended with a preternaturally lax ftate of the bowels ; which, in feveral inftances, might properly be called dyfenteric. The tongue was, from the firft, covered with a white fur. After three or four days, a black ftripe began to appear ; extending from the root, towards the extremity ; and gradually fpreading, as the diforder advanced, till the whole tongue affumed a black appearance. Even the teeth and gums were fometimes covered by this black' fur ; and in fome patients who afterwards re- covered. TO DR. E. H. SMITH* 55 In the treatment of this diforder, evacuation of fome kind, is undoubtedly neceffary in the early ftage of it. Venefection generally produced a temporary relief from the violence of the pain, and was, proba- bly, when the conftitution was firm and robuft, and the habit plethoric, frequently ufeful; but it did not appear to me to be important as a curative remedy. Emetics fometimes did well; and where there was a great degree of naufea> I thought them ufeful. But purging, with calomel and jalap, was the mode of evacuation I preferred, and generally practifed; and the remedy which of all others appeared to me mofl advantageous in the early ftage of the difeafe. ] It is unneceffary for me to fay any thing more, in this place, than that affiduous purging, in the begin- ning, and a plentiful ufe of the Bark, after the remif- fions had become fuch as to make it admiffible, were the effential parts of the management of this diforder. So ftrong was the tendency to diforders of this kind, that people continued in fome inftances to be affected with intermittents, or fever and ague, thro* the winter. Thefe were very frequent in the fpring, but with no peculiarities, and yielding to the common remedy with the ufual facility. During the month of Auguft 1795, I was in the county of Ontario, in the weftern part of the ftate of New-York. There, was, at that time, a diforder prevalent there, of the fame nature with that which I found rife in Sheffield, on my return, and which I am about to defcribe. It was chiefly exiftent in the neighborhood of ftagnant waters, and in fituations fimilar to thofe places, in this town, to which the dif- eafe was moftly confined. The treatment required was, of courfe, the fame. I 5$ LETTER FROM DR. W. BUEL, On my return to Sheffield, which was the 5th of September, I found a number of the inhabitants, about the North Pond, afflicted with a fever, which -, began to appear about three weeks before. The people firft attacked were thofe who lived neareft to die pond; whole families of whom were down at once. Numbers continued to be taken, daily, chiefly \ within the vicinity of this Pond, or within three quar- ters of a mile of its borders, till about the middle of ^ October ; after which time there were few inftances of new attacks. In this time, i. e. from the 1 oth of Auguft to the 2 oth of October, of about 200 (which is not far from the number of perfons living within three quarters of a mile of fome of the borders of this pond) not lefs than 150 were affected with more or lefs of this difeafe ; out of which number, but one perfon died, and that an aged man, previoufly debili- tated and difordered.—The number affected with1 f this fever, in all other parts of this town, did not, I believe, exceed thirty. Of thefe, three died : one, an aged woman : the other two, pregnant women ; of whom, one died in the fever, the other fuffered an abortion, and died fome months after, dropfical. . The difeafe, this year, put on a different form to what it did the laft. It might, with more propriety be called an intermittent, than a remittent fever ; though it was very different from a common fever ' and ague. It began, like other fevers, with an ague fit, attended vith pains in the head, back and limbs. The duration of this part of the paroxyfm was uncer- j tain. It was fucceedcd by a hot fit, whofe duration ! was, in different perfons, from fix to forty-eight \ hours. A remiffion, and, fometimes, nearly or quite* a perfect intermiffion, then came on ; but whofe du- ration was as irregular and uncertain as was that of the paroxyfm before. After the firft, the paroxyfms TO DR.' E. H. SMITH. 57 were not generally ufhered in by a regular ague fit; only fome flight chills were ft It; and thefe were ir- regular, both in degree and continuance. The length of the next fucceeding paroxyfms and intervals could, by no means, be calculated for, from the preceding: fo completely irregular was this diforder. The fever evidently tended to an intermittent form ; but it could neither be called quotidian, tertian, quartan, nor by any other name ufed by authors to diftinguifli the different fpecies of intermitting fevers. The pains in the head, limbs and back, were very fevere,* parti- cularly in the latter, which were fo univerfally in- tenfe, that the fymptom might almoft be confidered as charactereftic of the diforder. In the primse viae, flatulency was nearly a conflantly-attendant and very troublefome fymptom. Evidences of an increafed fecretion and excretion of bile, were generally pre- fent through the difeafe, but were particularly ob- fcrvable in the convalefcence. Some degree of ye'- Iownefs of the fkin, which was almoft univerfal, indi- cated a-reabforption of this fluid, and a depofition of it upon the fkin. This yellownefs was in two in- ftances, which I faw, very intenfe. A flight degree of delirium was very common, during the height of the fever. The appearance of the tongue was much the fame that it was laft year. My method of treating the fever of this year, was fimilar to that which I employed the laft year.— Purging, in the beginning, and afterwards a plentiful ufe of the Bark, appeared to me to be the moft fuc- cefsful way of managing it. In extreme cafes, parti- cularly, a free and full exhibition of bark, wine and laudanum, feemed the only means of falvation. It was abfolutely neceffary that the patient fhould be thoroughly purged, previous to the ufe of ftimulants, other wife the bark, wine 01 laudanum, would have $S LETTER FROM DR. W. BUEL, very pernicious effeas. I faw feveral inftances, at the weflward, where, by too early a ufe of thefe me- dicines, the fever was changed into a continued form* attended with a conftantly dry and yellow fkin, com- atofe fyrnptoms, &c. One of the inftances of extreme yellownefs, which I have mentioned, was of this kind, , and at the weflward. I removed this fymptom, and recovered the patient, by giving repeated dofes of calomel and jalap, fome perforative medicines, and afterwards the bark, wine, &c. Each purge, in this cafe, leffened the degree of yellownefs, very appa- rently. The other inftance of intenfe yellownefs, ~"* which I faw, was in this town, in the cafe of the pregnant woman, whom I have mentioned to have died in the fever. This woman's fever never had diftinct intermiffions. Several flight attempts were , made to adminifter the bark; but it would not do. Perhaps my timidity in the ufe of evacuants, on ac- count of her fituation, was injurious to her. The Bark did not fufpend the paroxyfms, in this diforder, in as fhort a time as it does in common in- termittents ; but, if the patient was properly pre- < pared, and the ufe of it was perfevered in, it never j failed to have the effect. Purging was probably ufeful in a twofold way : ■ Firft, by carrying off the fuperliuous bile ; which was, evidently, fecreted and excreted in a preternatu- j ral quantity : Secondly, by reducing the fthenic dia- thefis, which was, perhaps, always prefent, in the j early ftage of the diforder. 1 It is true, that thofe whofe fever was fufpended by the bark, were fubjeft to frequent relapfes, and to a a long and lingering ftate of couvalefcence. This drew \ an odium upon that medicine; and many were TO DR. E. H. SMITH. 59 induced to believe that it was owing to the ufe of it that people were fo long in recovering, and, of courfe, that it was improper. I am convinced, how- ever, from, very attentive obfervation, that thofe who did not take the bark, but fuffered the fever gradually to wear away, as it fometimes would, were equally fubject to thofe inconveniences. Indeed, this feems to be the nature of the difeafe. The old people in this town, who recollect the times when diforders of this kind have prevailed here before, and when the bark was not at all ufed, inform me that thofe who were afflicted with them, were a long time in recover- ing. It feems that, in all cafes, when patients have got rid of the fever, either by means of the bark, or otherwife, there remains an increafed difpofition to the formation and excretion of bile, and that this humor accumulates in the primas vise, till it firft de- ftroys the appetite and occafions naufea, and then excites a fpontancous djfeharge by ftool or vomiting, or a relapfe of fever, or both. A continuance in the ufe of fome laxative medicine, after a recovery, has a tendency to prevent thefe effects ; and, if ftrictly at- tended to, would probably prevent them, and per- haps obviate the difpofition to relapfe entirely. In reflecting on phenomena of this kind, the hu- man mind is anxious to fix on fomething fatisfactory as their caufes. Specific contagion, I am convinced, was in no inftance, which came u nder my obferva- tion, either here or at the weflward, the caufe of the propagation of the diforder. That marfh effluvia, to whofe action the inhabitants of fome parts of this town are fubject, is the exciting caufe, and is necef- fary to the production of the df|r city. This misfortune, common to every part of it, falls with peculiar heavinefs on that diftrict which has juft been fpoken of. The comparatively high and neighboring lands ofMorriffania andLong-Ifland, receive almoft folely the benefit of breezes from the north-eaft and eaft : The Sound, which divides them from the city, being too narrow to add much force and frefhnefs to a breeze nearly fpent on their heights. North, the ifland rifes into little hills, from which the wind paffes on to the high parts of the - city ; rarely > ifiting the low and intervening fpace; unlefs it may be the topmoft rooms of the houfes : i and, as the houfes are generally low, the effects of a wind from this quarter muft be inconfiderable.—- , North-wefterly, there is fomewhat more of an open- < ing ; but even this is fmall. Weft, fouth weft, and ibuth, the other parts of the town, which are higher, and thickly fettled, break the force of the gales from thefe points. So that, thus fituated, this quarter of TO DR. W. BUEL. 69 the city, though it were perfectly well laid out, would have but little chance for a free ventilation : irregu- larly difpofed and narrow as the ftreets are, we muft be convinced of the impoffibility of its receiving the neceffary fupply of frefh air. You will underftand me as fpeaking of a thorough ventilation, and in the fultry feafon, when it is moft neceffary : a partial fupply of air, equal to the fupport of a feverifh exis- tence, it undoubtedly obtains. Much of the ground, in the northern part of this diftrict, is fwampy, and abounds with little pools and puddles of flagnant water. This was efpecially true laft fummer and autumn ; there being great rains, and no adequate means for conducting off the water. Indeed, fo flat are fome of the paved ftreets, in this quarter, that the rains did not run down the gutters, but continued in little puddles, and were evaporated from the places whereon they fell. In the new ftreets, which are unpaved, and without any gutters, numer- ous imperfect ditches affifted the difpofition of the water to ftagnate. Thefe places were often mud- dy, when the fouthern part of the town was dry; and the fleams from them very offenfive, when the .dry ftreets, towards the North river, were perfectly fweet. Several of the paved ftreets, and indeed the greater number, in the diftrict of which I am fpeaking, are narrow and crooked ; fome with neither fide walks nor gutters, and by far the largeft portion of them, miferably built. Moft of thofe which are unpaved, are, in all refpects, ftill worfe ; the buildings chiefly wooden, and placed on the ground; the old ones falling to decay; the new, but imperfectly finifhed. Of them all, it may be remarked, that they are much expofed, fome of them more than others, to the full yo LETTERS FROM DR. E. H. SMITH. influence of the docks, whatever that may be, and ft cannot be falutary ; or to that of a broiling fun, from , early in the morning, till the middle'of the afternoon j 1 and fome of them, to both. 1 So much for the ftreets, generally : a few particu- lars, concerning fome of them, are neceffary to the •formation of a perfect idea of this diftrict. A line, drawn from the corner of Ferry and Pearl- ftreets, up the latter, to where William ftreet enters 1 it; then down William to Franckfort, and through J that, a part of Gold and Ferry-ftreets, to Pearl-ftreet jfl again, will form the ridge of a new cavity (included | in the principal boundaries above mentioned) which feems contrived, by art, for the dwelling place of fever. This court-yard of the palace of death, is di- vided by feveral difmal lanes, courteoufly denomi- nated ftreets; fuch as Vandewater, Rofe and Jacob- ftreets, &c. which form the borders to innumerable? 1 tan-vats. The whole is one vaft tan-yard, the firm parts of which feem to have been conftructed by art in the midft of an extenfive quagmire. To this placcv as far as I can difcover, there i-; no outlet. Think what muft be the condition of it, in the months of Auguft and September!—Yet human beings live , here ; and habit renders its noxious exhalations, in fome fort, harmlefs to them. It is remarkable that few perfons, regularly inhabiting this hollow, died otM the fever laft year. To thofe, whofe evil deftiny led 1 them to feek a new dwelling place there, it proved I highly peftilential. 1 Dover-ftreet is a fhort, narrow ftreet, running* m from the beginning of Cherry-ftreet, down to the. 1 Eaft river; and contains near twenty buildings.— ; The defcent, from Cherry into Water-ftreet, is very TO DR. W. BUEL. 71 rapid. As the expofure is nearly to the eaft, it re- ceives the whole effect of the fun, from 6 a. m. to 3 p. m. in the fummer. The defcent makes it eafy to keep the furface of the ftreet clean ; though it pre- vents a free ventilation. But it has been raifed, fe- veial feet, fince the buildings, which are moftly low, were erected ; fo that the road is, in many in- ftances, up to the middle of the lower ftory windows; leaving the cellars to the houfes, and cellar kitchens, without a communication with the ftreet. The yards remaining as before, are, of confequence, much lower than the ftreet; without vent; and, of necef- fity, all the water, and filth of every kind, which gathers in them, muft there ftagnate, ferment and putrify. Add to this, fome pf thefe yards are capa- cious, and contain little, decayed, wooden huts; fometimes built directly on the ground ; and contain- ing, oftentimes, feveral families. Water-ftreet, above Dover-ftreet, is chiefly com- pofed of low, decayed and dirty wooden buildings. This ftreet being either made-ground entirely, or raifed like Dover-ftreet, the fame is true of the fitu- ation of the houfes and yards. And, left any of the filth, or water, fhould drain off, from any of the yards, the weflern fide of Water-ftreet has been kindly converted, by the enlightened zeal of the directors of thefe affairs, into a perfect dyke ; which anfwers its defign, moft completely, by preventing even the flighteft leakage. Befide, as this ftreet lies directly on the water, it has the benefit of the whole force of the fun, the greater part of the day ; and of the exhalations from the docks ; which are here in great number, and in the higheft ftate of their per- fection. There is, however, abetter opportunity for frefh air, in this, than in fome other ftreets. Yet *VJ.{ even this is an advantage which the rage for im- L 7^ LETTERS FROM DR. E. H. SMITH, provement threatens to transfer to a new ftreet, ftill further out in the river ; which, if completed, may form another dyke, to the increafed pleafantnefs and health of this quarter of the town. Of Roofevelt, Catharine, James, Oliver, &c. ftreets, nearly the fame remarks are true as of Dover and the upper part of Water-ftreet: for though they are fomewhat wider, ftraighter, and have more good and new buildings in them, yet they are raifed in the fame manner, have funken yards, and under-ground apartments ; and Roofetelt ftreet has an open fink, where the drippings of the tea-water pump, after having gently collected all the filth in their way, are,; received ; and being juft enough to keep up a con- ftant dropping, and not enough to wafh the gutter, or the fewer, the ftench is moft intolerable, during the fultvy months. To many other of thefe ftreets the fame remarks , will apply ; and to fome with aggravated force : but what has been faid, will, perhaps, be fufficient to aid . your imagination in the conception of a juft idea of their condition : I mean of their neceffary and una- voidable condition. Of the Docks, it may be enough to mention, gc- j nerally, that they are badly contrived in every part o: the town ; and worft of all, in this part ; being ' broken up into numerous little wharves, thus form- . ing narrow flips, where the ground is left bare at ebb ; dde ; and where vegetable, animal, and excremen- ritious matters, being thrown in, at all times, inftead ' -of being caft into the ftream, ferment, putrify, and render the ftench truly peftiferous. Indeed, this is fo much the cafe, with all of them, in the fummer, that, except to perfons habituated to their exhala- TO DR. W. BUEL. 73 tions, they are abfolutely intolerable; exciting, in perfons of a delicate make, immediate vomiting ; and in others naufea, indigeftion, head-ach, or fome tem- porary illnefs, when expofed to them but a fhort time. In addition to the above-related facts, concerning tho condition of the ftreets, in that part of the city where care was moft needed, it may be remarked that, at no time, was there ever fo great an apparent inat- tention to preferving them clean. Befides the impe- diments which the level nature of the ftreets, in manv parts of the town, prefented to the draining oft" of the filth which is conftantly accumulating in large towns like this, artificial impediments were permitted ; as if death were not fufficiently active, and needed the aid of the magiftrate. In all the ftreets where buildings were going forward, the workmen were allowed to reftrain the couffe of the water, in the gutters, by forming little dams, for their convenience in making their morter. The effect of this ftoppage of water was fo great, that even in Broadway, one of the ftreets the beft calculated of any in the city for free ventilation, in that part of it where the new Tontine Tavern was building, the ftench was exceed- ingly offenfive. And in this condition was it allowed to remain for near two months ; though it was al- moft under the windows of the principal magiftrate of the city. If this were true of the wideft, and one of the beft aired and cleaneft ftreets, of New-York, what think you wras the ftate of thofe narrow, crook- ed, flat, unpaved, muddy alley?, mentioned above ? No one can form even a faint.idea who has. not walked through them, in the middle of fome one of thofe deadly, fuiibcative days, which we experienced in September laft. 74 LETTERS FROM DR. E. H. SMITH, But this is not all: befide thofe maffes of femi- putrid vegetable and animal matters—cabbage, tur- nips, the heads and entrails of fifh, &c. which, at all times of the year, out of compaffion to men who might be ufefully employed as fcavengers to the city, are allowed to complete the putrefactive procefs, un- - difturbed, in the middle of the ftreets,-—the fight and the fmell were fhocked, at every turn, by dead rats, fowls, cats, dogs and pigs. So remarkably was this the cafe, that I queftion whether there could have ; been found a fingle ftreet, alley, or even bye-lane, of j any tolerable length, which did not lend its aid to render this exhibition full and frequent. The preceding ftatement, melancholy as it may I appear, will convey a very inadequate idea of our misfortune, in refpect to fituation, without fpecial- ■ information concerning the feafon, as it appeared here, during the reign of the fever ; and a knowledge [ of the people who moftly inhabited thefe parts of the^ < city, and on whom the feverity of the diforder was moftly inflicted. With this knowledge I fhall en- deavor to furnifh you; but the length which this letter has already acquired will excufe me, to you, % for poftponing the attempt, to a future opportunity. • \ 4 t LETTER THIRD. Some Account of the Seafon of 1795. Physicians, from the earlieft ages of medical re- cord, have remarked that great peculiarities and irre- gularities of feafon, have exercifed an unfriendly influ- nce on human health: And Hippocrates, himfelf, takes I TO DR. W. BUEL. 75 notice of the difficulty, which hence arifes, of forming a proper judgment, and adopting a fuitable method of cure, in thofe difeafes which occur under fuch cir- cumftances. The importance of this divifion of my fubject, makes mc regret that it is in my power to fur- nifh you with no other than general information. You will be the more ready to overlook this defect, when you recollect that I do not pretend to-deliver a hiftory of the fever, and are informed that there is fome probability that this particular delect will be fuppiied by another hand. Generally, then—every one knows that the fum- mer and autumn of 1795 were cxceffively fultry and exceffively wet. Every article of houfehold furni- ture, or in ufe about a houfe, fufceptible of mould, was fpeedily and deeply covered with it. It feemed to penetrate places where we fliould have deemed its appearance impoffible. A friend of mine found a pocket-book of Morocco leather quite mouldy ; though it was in the drawer of a private defk, inclofed within a large defk—both of which were ufually locked—and covered by papers. Boots and fhoes hung up by a wall, near a fire-place, heated every day, contracted mould within twenty-four hours. Meats fpoiled in the market-place uncommonly quick ; and thofe which were brought home, appa- rently frefh and good, in the morning, were often found unfit to be eaten, when cooked and brought upon table. Efculent vegetables, in general, and efpecially fruits, were unufually poor, tough and taftelefs. The peach, particularly that called the cling-ftone, was fcarcely digeftible; and often occafioned temporary J6 LETTERS FROM DR. E. H. SMITH, illneffes, quite fevere, while it doubtlefs aided in the production, or aggravation, of the fever." Flies were very numerous and troublefome, in every part of the city, in the beginning of fummer; but they fuddenly difappeared, about the middle of July, from the more airy parts of the town, collecting i in fwarms, in the lefs healthy parts, and fucceedea£; every where, by clouds of mufketoes, incredibly large and diftrefling: and thefe continued to affli& us, long after the time when they commonly depart. ] Almoft every perfon fuffered exceedingly from the bites of thefe infects ; and foreigners efpecially. In fome they occafioned univerfal fwellings, and erup- i tions, fomewhat like Pemphigus ; and in others nu- merous little ulcers. Thefe laft, a phyfician of my acquaintance, faw even in a native American. The irritation, reftleffnefs, and confequent watchfulnefs and fatigue, occafioned by thefe animals, no doubt ; predifpofed the well to be affected by the fever; while they extremely harraffed the fick, and retarded their recovery. During the whole of this feafon, I remember butj one thunder-ftorm ; and this was very gentle. There , was but a fingle hard clap of thunder, for more than four months, that I remember ; and very little thun- ! der and lightning, at any time. I * Vegetable grow th was uncommonly rapid and abundant, in the fummer of 1795. I mention this that no miftake may arife from the above remark concerning efculent vegetables. The more rank they grow, beyond a certain degree, the more taftelefs they are ; and the influence of a wet feafon, in rendering roots and fruits tough, as well as imipiJ, is well know.). It is worthy of rcmcrk, thai rr.sr.y fruit-trees, plumb-trees in particular, bloffbmtd a iecond time,).?.% year, and produced an . imperfect and fecoiK5. crop of fruit. TO DR. W. BUEL. J J Our rains, exceffive in quantity and frequency as they were, feemed to have loft their wonted power of cooling the air. In thofe ftreets, moft unhealthy, and leaft ventilated, this effect was, in a degree, ob- fervable ; but, in the airy and healthy parts of the town, on the contrary, they never failed to render the heat more intolerable ; and the fteams from the hot pavement were like thofe of a vapor bath. The clouds, too, feemed to fhut out every kind of breeze. —One of thefe heavy rains, which continued two or three days, feemed to poffefs all the qualities of fleam. It pervaded every recefs of the houfes, and diffolved the beft glue—fo that furniture, in many inftances, which had been long Handing, fell in pieces. Fogs, which Dr. Lind enumerates among the figns of an unhealthy climate, and caufes of difeafes—page 134 of his Effay on hot climates, he.-.—prevailed in the city, and fpread over all the moft unhealthy parts, in particular, in a remarkable manner,—in the even- ings—for a confiderable part of September and Oc- tober. The oppreffion, thicknefs, ftench, and un- comfortablenefs in every refpect, of thefe fogs, was very uncommon. In a phyfician, who, in the per- formance of his profeffional duty, was expofed to their influence feveral hours, one night, they pro- duced bleeding from the gums and fauces, and black and fetid ftools.—On the city watchmen, however, they had no fuch effects. About the firft of Octo- ber but one perfon had died out of their number ; and he was a man who returned to the city, a little before, and refumed this occupation, after having been fome time abfent in the country.—Whether this fecurity of the watchmen is to be attributed—as it is by Dr. Rufh, to the influence of the cool night- 7& XT.TTERS rilOM DR. F. H. SMITH, air*, or to that cf habit, I leave others to decide. It is not impofi.bie but that both may concur in pro- ducing this infenfibility to the caufe of difeafe in others. To thir imperfect account of the feafon, which, de- fective as it is, appeared to me too important to be omitted, 1 have one fact to add, on the authority of a gentleman diilinguiihed for his attention to meteo- rological phenomena. He informs me, that no Aurora Borealis has been feen, of any magnitude, in our country, north of Pennfylvania (as far as he can learn) for near four years, till the latter end of Sep- tember 1795 ; and adds, that his father, a refpectable clergyman, now about 70 Years of age, who noticed the fame abfence of thefe appearances, remarks, that, according to his uniform cbiervation, fome uncom- mon ficknefs has never failed to follow a long conti- nued difappearance of thefe phenomena. How far the experience of other obfervers will tend to con- firm this ftatement, I have had neither time nor op-. portunity to inquire. And. if it be admitted as in- difputable, it may ftill be queltionable, whether this is to be regarded as a caufe of difeafe, or whether this difappearance and difeafe, Le not co-ordhjate effects of a common caufe. * Page 35 of his account of tho Fever of Philadelphia: " I " aiciibe it to .he bclltual imprison of the cool night air upon " the bodies of the city wutehtv.en," i. :. By habit, as ufed' above, is mea':t that condition of the body'which is produced by euflomary ex] 1'iuic to any particular imprcfiion ; audi dclign only to fuggtit a piobahillty that the watchmen eiev.^.'d the fever, as much from l\.Jw bavin- been rendered b) bv.bk i; 'uibble to the influence of the c.^e.-ia, ic. of the in.healthy p;-: t a of ti:.- city> as from the iiukicnee cf cokh TO DR. W. BUEL. 79 LETTER FOURTH. Some circwn/lances relative to the principalfofferers by the Fever of 1795. It is a fact, generally admitted, I believe, that, of thofe who were fick and who died of the Fever of 1795, the greater number were foreigners : perfons, either juft arrived from other States, from the Weft- Indies, and from Europe ; or who had not been many months, or years, fettled in this city. It is probable that the proportion of citizens, who died, to ftrangers, did not exceed one to feven. Of thefe ftrangers, it is thought, a large number were Irifli; and there are fome reafons why this fliould be true ; but I cannot pretend to know it to be fo, from my own obferva- tion. The caufes productive of difeafe in foreign- ers, in thofe of this nation in particular, are numer- ous, and fome of them deferve particular attention. This I defign to bellow upon them, after remarking, that, both among natives and foreigners, the feverity of the difeafe was experienced by the poor. I. Dr. Blane, in his obfervations on the difeafes of feamen, remarks, " that it fometimes happens, that a " fhip, with, a long eftablifhed crew, fhall be very " healthy ; yet, if ftrangers are introduced among " them, who are alfo healthy, ficknefs will be mu- " tually produced;" and Dr. Rufli, in the firft vo- lume of his "Medical Obfervations and Inquiries" takes notice of this remark of Dr. Blane's, and con- firms it, by a reference to the experience of: our coun- try, during the late war. Thefe are his words— " The hiftory of difeafes furnifhes many proofs of " the truth of this affertion.—It was very remarkable, Eighteen paffengers came in the above brig, all in good health,—who have continued in this ftate to the prefent day.—Three days after the above event, the Health-Officer vifited the fame brig, in as good health as ufual. Signed COMFORT BIRD. Sworn before me, this feventh day of Septem- ber, one thoufand feven hundred and ninety- five, in the City of New-York. C. DUNN, Jun. Of the undoubted veracity of Captain Bird I am afiured by Dr. Dingley, who is perfonally acquainted with him, and attended him, at the time, for the dyfentery mentioned in the depofition. The opinion, therefore, that the Yellow Fever, or a contagious difeafe, was brought into the city, laft year, 'by the brig Zephyr, feems wholly unfupported by evidence. Neither is it neceffary that any imputation fhould reft on the memory of Dr. Treat. He faw the mariners after they had been long affected by theFever and ague, and * perhaps with fome fever upon them at the time ; and;' from the yellownefs of the fkin, common to the ad- vanced ftate of that difeafe, efpecially in hot climates, might be eafily induced to fuppofe it a remittent*. This, however, is mere conjecture, and not neceflary to be admitted, fince the fact of the men having been fick feventeen days, previous to their embarking for our coaft, is ample proof that they could not have' been affected by the fever which prevailed and was TO DR. W. BUEL. 101 fo mortal, here.—Indeed, the whole teftirnony in favor of the idea of importation, is too loofe and flight to build any rational opinion upon. The very words of the Committee are calculated to ftrengthen a con-' trary opinion, if rightly confidered ; for they not only countenance the idea that the people of the fhip Wil- liam became fick from the unhealthinefs of the place where they dwelt, but, alfo, that the Fever had made its appearance, in various other of the neighboring houfes and ftreets, previous to their being feized with it. And .what confirms the truth of this opinion is, that perfons were taken with the diftemper, about this time, in other parts of the city, who had no connection with the brig Zephyr, nor with any other [ veffel, and whofe illnefs may be fatisfactorily ac- i counted for from their fituation, in other refpects. 1 An inftance of this kind fell under my own obferva- \ tion, the laft of July ; feveral fimilar cafes have been I related to me ; and one, if I am net mifinformed, J occurred in the New-York Alms-houfe, where the \. difeafe was diftinctly marked, before Dr. Treat's ill— ,. nefs.—The following flatement of facts, too, will ff, convince every candid mind, that we ought to look I at home, for the caufe of this Fever. The fhip Connecticut came to Fitch's wharf, about the 20th of July—I think it was on rhe 21ft : fhe H had juft arrived from fome part cf England, and the people were perfectly healthy. No veffel fufpected of being infected, came to this wharf, ■\J. during the feafon; though the fhip William lay at f f* the next wharf, at the diftance of about two hundred feet,—and Mr. Fitch gives the moft pofitive affuran- ces that all the articles in his flore, at this time, were in good condition. At this wharf the fhip Connec- ticut continued till after the middle of Auguft. The owner was employed about the fhip, 'great part of IP2 LETTERS PROM DR. E. H. SMITH, the day ; but ate and flept in an airy part of the town. The people of the fhip either flayed on board, or at public houfes near by.—On the evening of the 25th of July, the owner was feized with the fever; I faw him the 27th ; he had good accommodations, was in a favorable part of the town, in the thh d flory of the houfe, and recovered after an illnefs of about ten days, which was never very dangerous, though the p.ttack%'as fevere.—About this time, one of the mates* the fteward, and two of the mariners, of the fhip Con- necticut, were feized in the fame way, and witli the fame fyrnptoms, as the owner. They continued in the fhip, or its neighborhood, and all died. I did not fee them, but was informed, by the owner, that the mate, in particular, vomited large quantities of blood, and expired delirious. Three perfons, who were in Mr. Fitch's ftore^ were taken fick, and two died, of the Fever. One fickened on the 26th of July, one on the 6th, and the other on the 9th of Auguft- It was common for all thefe perfons to fit ct feveral hours, in the morn- " ing, in the flore, with empty ftomachs,—inhaling " the effluvia of the night." One of the firft perfons, who died of the Fever, was one " who lived at the head of the wharf, and " had been confined for feveral months with a rheun " matic complaint." For the facts contained in the two laft paragraphs, I am indebted to a communication from Mr. Fitch to Dr. Dinghy, which that gentleman has allowed tne to make ufe of on this occafion. The account which' it contains of the condition of the wharves in his neighborhood, adds new force to the other teftimonj. in favor of the opinion that the Fever originates here ; and is too much to the purpofe to be omitted. Thefe are his words:— TO DR. W. BUEL. 103 u I am pofitive that the diforder has originated " from local caufes—becaufe, it has appeared in this " quarter, at the fame feafon, for feveral years paft: *' the caufe why it has is, to me, myfterious ; but *' what appears to me moft probable is, the central " fituation, and the motion of the tides. The *< tide of flood fets directly into thefe wharves; col- " lecting all the vapors and effluvia of thej^city.-— " The fituation of the ground, between Water and " Cherry-ftreets, is rendered noxious by railing " Water-ftreet, and confining the ftagnant waters.— " The emptying of tubs into the head of the docks, " inftead of the end of the wharves, although not " peculiar to this part of the city, is a horrible nui- " fance ; particularly in time of ficknefs.—-The pon- " ding of water, by running a bulk-head athwart a " dock, and leaving the vacancy for years, to be " filled up with every fpecies of filth and putridity, is " an object worth your attention." A confirmation of the facts, and fome of the opi- nions, contained in this extract, may be found in a very lingular epiftle from the late Dr. Wm- Pitt Smith, to Dr. Duffield fen. of Philadelphia, dated Septem- ber ift, 1795 ; which I prefume you have feen and are poffefled of. On the whole, though I am not prepared to main- tain that infectious difeafes, and the Yellow Feyer among others, may not be, and have not been, im- ported, and thus fpread over parts of our country, yet this is the moft that can be allowed to the coun- tenancers of the doctrine. For, after all, the tefti- mony of numerous fads furnifhes clear, indubitable, and decifive evidence, that other and peculiar cir- cumftances muft concur with fuch importation, to P S0-4- LETTERS FROM T>R. E. H. SMITH, effect any general diftribution, circulation,' or influ- > ence cf the difeafe. Frequent inftances have occurred, nay do occur every year, of perfons returning, from the Weft-Indies, fick with the Yellow Fever; Ian- guifhing, for fome time, in the houfes of their pa- rents, or friends; recovering, or dying ; attended by numbers, during their illnefs; their very clothes,' where ijaey have died, afterwards worn by their re- lations ; and yet no ill effects following therefrom.— While I refided at Wethersfield, in Connecticut, I had opportunity of obtaining precife information of feveral fuch cafes ; and it is a well-eftablifhed fact, in many inftances during our Fever, and efpecially dur- ing that of Philadelphia, in 1793. The whole, therefore, that can be granted, or ought to be affumed by thofe who maintain the dift eafe which prevailed in New-York in 1795, to have been imported is,—That infection may be brought into any place (and therefore into this city) from abroad ; that, under certain circumftances of the place, where it is introduced, it becomes very active and deftructive ; but that, when thefe circumftances do not exift, however the perfon immediately af- fected,—if it be introduced by a fick perfon—may fuffer, it is harmlefs, fo far as the general health of that place is concerned.—If the fubject were viewed hi this light, as moft affuredly it ought to be, the queftion of importation, or non-importation, would fink into it's merited infignificance ; the efficient eaufe, the caufaf.ne qua non, of fuch Fevers, would be clearly difcerned as depending on local circum- ftances ., capable of being wholly changed ; the abfo- hite madnefs of further delay, in effecting fuch a change, would be diftinctly and deeply felt; a becom-' ing fpirit would animate the citizens; and fuitable exertions fpeedily place us beyond the poffibility of TO DR. V. BUEL. 105 being fubjecled to a misfortune, fimilar to that which has been already fuftained. For it is inconceivable that the nature and extent of the evil fhould be un- dcrftood, and the remedy not be applied: and a comparatively flight and temporary facrifice of pro- perty, would render this city, in reality, what the miftaken policy, or pride, of fome of its inhabitants now falfely reprefent it,—as healthy as any in the world ; and leave nothing to fear, either from the Fevers of the Indies, or the Plague of the Levant.—But, while people continue to fofter a ridiculous vanity, con- cerning the city in which they refide ; while they fear that its reputation will be wounded, by permitting an idea to get abroad, that it is unhealthy; while thofe engaged in commerce cherifh the error, from an apprehenfion that their interefts would fuffer from a difclofure of the truth ; while men, inverted with the facred character of phyficians, countenance falfe opinions, either through ignorance, a reprehenfible ti- midity, or that they may gather undeferved popularity andwealth; and while the magiftracy are more actuated by a mean regard for offices dependent on popular opi- nion, and maintained by a compliance with it, at all hazards, than by a juft and enlightened zeal for the fafety and happinefs of their fellow-citizens ; Truth may be fpoken, but there is no hope that it will be attended to. Confederations of fuppofed intereft, h various and fo forcible, take deep root in the minds of men who look only to the prefent moment, and are either incapable of comprehending the whole of a fubject, or unwilling to beftow on it the neceffary confideration. Thus circurnftanced, they ftrive to banifh from others, and to fmother in their own breafts, thofe convictions which irrefiftible evidence forces upon them: as if it were poffible that truth could be noxious.—Nothing can be more melancho- ly than to obferve this wilful blindnefs, this obili- nate perfiftency in error, the confequences of which ICQ" LETTERS FROM DR. E. H. SMITH, have been fo dreadful already, and threaten to be ftill more fo hereafter.—Were it poffible to imprefs the truth vividly on the minds of the great body of. citizens; to rouze men into action; to excite a. generous difregard for temporary advantages, and a lively intereft for the future welfare of themfelves and their pofterity ; a few weeks might enable us to bid defiance to death, in many of the forms in which he nowlffails us. LETTER SEVENTH. Was the Fever of ijgs an Epidemic? Was it Con- tagious ? Having determined, to my own fatisfaction at leaft, what were the remote or predifpofing caufes of the Fever of 1795,1 might now proceed to a defcription of the difeafe itfelf, were it not proper to take fome' notice of two queftions, which have been confidera- bly agitated, viz. Whether the Fever was, as the Health Committee term it, an Epidemic ?—And, as fome fuppofe, Contagious ?—On both thefe queftions, I fhall deliver my opinion, inasfuccinct a manner as the fubject will permit. Was the Fever epidemic ?—A principal difficulty oc- curs in the very outfet of this enquiry ; for different writers have made ufe of the term Epidemic, diffe- rently ; fome giving it a rsii:eral, others a morepartkui' lar and precife lignification. Thus Van Swieten, in his Commentary on the 1380th Aphorifm of Boerhaave, places epidemic in conrradiitinction to endemic ; while Cleghorn, a writer of deferved authority, in the In- troduction to his Obfervations on the Difeafes, &<.\ TO DR. W. BUEL. lojf of Minorca, p. 74. conftitutesa clafs of endemic dif- eafes, which he divides into epidemic and fporadic.— Examples of like diffimilarities, in the ufe of thefe words, are frequently to be met with, in authors of equal credit. And thus it may poffibly happen, in the prefent inftance, as on many former occafions* that the whole contention arifes from different con- ceptions of the import of a particular word.—But our bufinefs is rather with facts, than with definitions ; I fhall ftate to you, therefore, what appears to me to have been the truth ; and, perhaps, in the conclufion of my ftatement, a definition will be found. In the firft place, every perfon converfant with the practice of phyfic in New-York, knows that a Fever, generally of the remittent or continued kind, and va- rioufly denominated by medical writers, prevails in this city, to a greater or lefs degree, every year ; per- haps I may fay throughout the year—but, certainly, in every part of it, except the winter, and particularly from July to December : its greateft height being in the months of Auguft, September and October. The violence of this difeafe is increafed or diminifhed by conftitutional peculiarities, and by the particular fitu- ation of the patient in refpect to air, temperature, &c. &c. Its univerfality, likewife, may be confidered as dependent, in a degree, on the fame caufes.—Cir- cumftances, peculiar to fome fituations or individuals, occafion it to prove mortal, with high marks of ma, * lignity, in certain inftances, almoft every year. That an extenfion of thefe peculiarities, fo as to make them common to the citizens generally, would pro- duce the fame effects on the many, as on the few, feems hardly controvertible. Now, this appears, to me, to have been the cafe, the laft year ; and I have no doubt of the identity of the Fever which then raged here, with that which has prevailed here in 108 LETTERS I ROM DR. E. H. SMITH, former years ; and confider it only as a higher grade of the fame difeafe.—Compare the hiftory of Fevers, in Sheffield, with that of Fevers in New-York.—We have a Fever, every year, at a particular feafon, ufu- ally called the bilious-remitting Fever : in Sheffield at the fame feafon, a Fever prevails, called the inter* mitring Fever. This lafl evidently depends on the peculiarities of Sheffield—fuch as its ponds, marfhes* &c.—So, in my opinion, does the former arife fron^ the peculiarities of New-York.—The feafon of 1795 was a remarkable one : Was there any apparent change in the Fever of Sheffield ? Yes : the fyrnp- toms were remarkably heightened; fome new ap- pearances were obfervable ; and the difeafe aftonifh- ingly obftinate. And was not this, alfo, true of New-! York ? Wrho will venture to deny it ?—Were either of thefe Fevers propagated to other, or neighboring, places ? No. You have certified this of the Fever in Sheffield; and I have heard of no inftance of the kind, in relation to that of New-York. Both Fevess, then, were proper to the places in which they prevailed ; and the inference which it would be natural to deduce from this is, that both were endemic, and not epidemic : for the term epidemic feems to include in it the ca-.( pability of diffufion or propagation, without refpect' to the fituation and conftitution of the patient; which the term endemic certainly does not. But, which- .j ever of thefe titles may be regarded as moft appropri- ' ate, the fact will not be varied by the ufe of either; and that you will underftand to be, according to my belief, as above-ftated: That the Fever of 1795 was- no other than a higher grade of that which prevails here, in the fame feafon, every year ; deriving its fe- verity entirely from the peculiarities of the feafon, &c. as related, at large., in the preceding letters. TO DR. W. BUEL. I09 Was the Fever contagious ? Concerning the anfwer to be made to this, as well as to the former queftion, there has been fome difpute; but, in this cafe, as in that, as much difficulty has arifen in fettling the im- port of the phrafeology, as in determining the fact. If by the queftion it is meant to inquire, whether the well became affected with the Fever, in confe- rence of the contact of a fick perfon, or the cloath- f ing of a fick perfon, or from the performance of the offices of friendfhip, charity, and menialitv, to thofe who were fick,—I anfwer that no fuch cafes have come to my knowledge ; whereas numerous inftances of fuch contact fell under my obfervation, and have been related to me, to which no ill effects fucceeded. A number of perfons, not lefs than ten or twelve, removed, with the Fever on them, from New-York to Stamford, 40 miles ; but no perfon in Stamford, befide them, ever had the diforder. Mr. Fitch, the gentleman mentioned in the pre- |, ceding letter, attended the young men who had the \ difeafe with him, and to ufe his own words, " lodged P " in the bed, warm with the effluvia of the body of ' " the young man who died at his houfe"—and ne- verthelefs, he had no Fever. Dr. Treat, according to the account of the Health- ' Committee, and of his phyficians, died of the very worft degree of the Fever ; yet he communicated it to nobody. A patient of Dr. Dingley's, in Ferry-ftreet, who was feized with the difeafe, without any previous communication with any fick perfon, and as earlv as the 17th of Auguft, and who died with it, commu- nicated it to none of his attendants. And the fame is true of feveral other patients of the fame gentle- man. HO LETTERS FROM DR. E. H. SMITH, The writer of fome ingenious ftrictures on Dr. Mitchill's Pamphlet, remarks, in a note fubjoined to his firft paper, that he has, " in common with many of " his fellow-practitioners, indulged, without thefmallefo-, " ill effed, a much more frequent intercourfe with his " patients, in this difeafe, than ufual," &c. And the Doctor himfelf, though he admits the poffibility of fuch fevers becoming contagious, or being propagated by contact, &c. exprefsly denies the Fever of i7g$ to have been fo. But there would be no end to an enumeration 6? fimilar facts; I fhall only add, therefore, that I made ufe of no precaution whatever, in refpect to fuch com- munication with patients; that I have been, for more than two hours, fhut up in a fmall room, with a per- fon laboring under the worft fyrnptoms of the Fever; have watched feveral nights, and performed the moft fervile offices, with a near friend, who was fick with it; and never fuftained the leaft inconvenience from fuch expofures*. But, perhaps the advocates for the Contagious, or Infectious, nature of the difeafe under confideration^ do not intend to confine the meaning of the term Con- tagion to that fubftance, whatever it is, which is ge»- nerated in an unhealthy body, and by application to a found body, excites in it a fimilar unhealthinefs. They may mean to defcribe, or defignate, by it, tha ftructure, conftitution, or vice, of the atmofphere which difpofes to, or excites difeafe. If fo, they arc in fault—for they employ the fame term to defig- naie two different facts.—But let us not difpute m * I might fuperadd to all this, the ambiguous tcfthnony of another Phyfician, who, in proof of the uninfcctieus nature of the Fever, affirmed that he had " hr.d thirty patien:s with it, and " had taken tlie breath of all of them." TO DR. W. BUEL. II I about words. Perhaps, the following ftatement of ,«ny opinions, will lead us to the formation or attain- ment of fome more accurate notions on this point. Owing to a variety of caufes, which have been enumerated in the courfe of thefe letters, I fuppofe the atmofphere of New-York to have become vi* liated, in 1795, to an uncommon degree: that there was either an unufual abfence of that principle necef- fary to fupport healthy life, or an extraordinary con- centration, diffufion, or quantity, of fome other, un- friendly to healthy life. From the operation of one, or other, of thefe ftates of the atmofphere, and of the caufes above-mentioned, on the bodies of the refidents in this city, I fuppofe a predifpofition, ' greater or lefs, according to the fituation and other circumftances of individuals, was formed, in the citi- zens, generally, to the Fever which prevailed here that year. With fome pterfons, this condition of the atmofphere, of itfelf, might.be fufficient to produce in them difeafe. But, ordinarily, I believe, the aid I of fome caufe, which fhould difturb the regularity of the diftributions, or functions, of the body, was re- quired to bring the fyftem into a ftate of febrile ac- j[ tion. Such, for inftance, as intemperance in eating or drinking, fudden fright, fatigue, or indeed, any eonfiderable irregularity in what Syftematics call the Npn-Naturals. This condition of the atmofphere, I fuppofe, ac- quired ftrength, daily, as the feafon advanced; or, in other words, the power of the atmofphere, &c. to predifpofe to the Fever, was increafed, as the feafon progreffed. I fey to predifpofe,—for I fufpect it fel- dom, of itfelf, produced -the difeafe, after that had at- tained its height, in thofe who remained here con- 2 12 LETTERS FROM DR. E. H. SMITtt, ftantly. Though, on perfons coming into the city, from, abroad, it doubtlefs operated with much greater^ force, in many cafes, than on the citizens, at any tiraA' This is eafily accounted for, from the known effects* ofcuftom. For Jv " The monfter Cuftom, who doth, &c. " - '.......1S angel yet in this." The fyftems of thofe who continued here became habituated to the atmofphere ; and while thofe who came here from the country, with ruddy faces, funk down in death, the pale and yellow beingswho ftalked through our ftreets, derided difeafe, and purfued their cUftomary occupations.—But, to return from this di- greffion. Not only am I convinced of the accuracy of the preceding ideas, but I have*no doubt that this vice of the atmofphere was rendered ftill greater by exhala- tions from the bodies of the fick——It is a point well-eftablifhed in medicine, that the air of a room is rendered unfuitable for refpiration, if a num- ber of healthy perfons are obliged to breathe it over. feveral times, without the admiffion of frefh air from' abroad. So injurious is fuch a confinement, in re- fpect to air, to the human body, that it has, in nume- rous inftances, produced terrible febrile, difeafes. And/ if fuch effects arife from the repeated breathing ovei the fame, or nearly the fame, air, by healthy perfons, we fhould naturally conclude, as is the fact, that fuch repeated refpiration (efpecially when united with the conftant exhalation from their bodies) by the fick, muft be ftill more pernicious to health.—You will pardon me for the introduction of remarks fo trite and familiar, for the fake of the ufe I wifh to make of them ; which is no other than this—I have mention- TO DR. W. BUEL. 113 ed it as my belief that the ftate of the atmofphere was fuch, in this city, the laft year, as, in conjunction with the general influence of the caufes producing that ftate, to predifpofe to, and, in fome inftances, pro- duce, the Fever; and that this ill-conditioned atmof- phere was rendered ftill more noxious by means of the numbers who became fick, in the courfe of the feafon ; and to this I would add, for the reafons con- tained in the remarks above, that I think it not im- V probable that fome were affected with the Fever, in confequence of the further vitiation of the atmofphere by the fick, who, without that circumftance, would have remained free from difeafe. So, likewife, there may be perfons, the.balance of whofe health is fo tre- muloufly fenfible to every external influence, as to preponderate to the fide of difeafe, on the flightelt impulfe of its caufes. With fuch, the meje conta& of a fick perfon, or a tranfitory expofure to. the efflu- ^ via arifing from a fick body, may be fufficient to pro- te -duce Fever; and inftances of this kind may have hap- ;' pcned, in the courfe of the Fever in queftion. Such I1, cafes, however, muft have been extremely rare, if jt' there were any ; and no one has ever come to my knowledge.—But, with regard to Fevers produced by fuch a ftate of the air, as above-defcribed, even when |'i aided by the mixture of human efiluvia, arifing from fick bodies,—if thefe are to be called Contagious dif- eafes, and the caufe which excited them Contagion, fo, hkewife, may all other Fevers on the fame principle, f continued, remitting, intermitting, Fevers,—be called Contagious, and their caufes, as marfh miafmata, &c, I;' f Contagion.—Now, to fuch a ufe of terms I have not ), the leaft objection, provided the perfon who employs them, be uniform and explicit in his application of them. 114 LETTERS FROM DR. E. H. SMITH, To conclude,—If, in fpeaking of the Fever ot* j 1795, the epithet Contagious is meant to exprefs that it was communicated by contact, &c. like the Small- j pox, Meazles and Plague, I muft repeat it, I find no good reafon for admitting this to have been the fact; 1 but, for the reafons before alledged, I think there is juft ground for a belief that the Fever was never ex- cited in this way. But if, on the other hand, the ? term Contagion be meant to convey an idea of the in- ,..; fluence of the atmofphere to predifpofe to, or pro- duce, difeafe,—whether that influence arife from the abftraction, or addition, of a principle, or be diftinct from human effluvia, or combined with them—there appears no feafon for denying the Fever of 1795 to J have been Contagious.—Still, as the term Contagion is not generally ufed in a fenfe fo reftricted, as in this fecond inftance, but is often employed by the fame writer, to exprefs both the caufe of the difeafe com- municated by contact, &c. and of that produced by the influence of the atmofphere, there feems to be a pro- priety in rejecting it altogether, in theprefent inftance, or at leaft in confining the ufe of it, to defignate a tingle mode of producing difeafe ; and, according as it is applied in the former or latter inftance, the Fe- ver of 1795 may be denominated Contagious, or the reverfe. , I have now gone through with the confideration of jN all the fubjects, preliminary to an account of the dif- ffl eafe itfelf. In my next letter, I fhall lay before youfc' the refult of thofe fcanty obfervations which I had S opportunity to make.—Knowing the caufes of their S imperfections, you will not fail of extending your II charitable indulgence to their author. 1 TO DR. W. BUEL, "5 LETTER EIGHTH. Some Account of the Symptoms of the Fever of 179S' After the frequent confeffions, which occur in the preceding "letters, of the circumfcribed fphere ot mv obfervation, it were prefumptuous in me to pre- tend to deliver a regular hiftory of the fyrnptoms of the Fever of 1795. You will obferve, from the ac- count which I fhall tranfmit to you, that the appear- ances it exhibited were too various to authorize iucti an attempt in any one who had not opportunity to ex- amine them, in relation to numbers of the fick. It is proper, therefore, that I warn you, once more, to confider what is here delivered as the refult of my own obfervation only—except where it is exprefsly mentioned to be otherwife. The Fever of 1795 was, generally, fudden in its accefs; fo much fo, m fome inftances, as to referable convulfions. In a lefs number of cafes, it came on gradually, and after a flcwly-increafing^ illnels ot feveral days. It began with great pain of the .head, heat and rednefs. of the face, and fullnefs and rednefs of the eyes, accompanied by altrong, full, tenfe, pulfe, and an almoft univerfal cofhveneis. Pains in the back and limbs were common; but not as much fo as of the head. A great inquietude, or anxiety, of the ftomach and breaft, was common j approaching, fometimes, to fyncope, and fometimes a vomiting, which foon ceafed, or continued, at in- tervals, through the diforder.—Tl^.Fever which now commenced was rarely adhered in by a chill, and con- Il6 LETTERS I ROM DR. E. H. SMlT^, tjnued for a greater or lefler period, according to* ] circumftances, with fo many varieties and combina- tions of fyrnptoms, as to render it impoffible to purfue , a regular defcription. I fhall, therefore, difpofe my remarks under feveral heads; preferving as much J connection as circumftances will permit. I. Though the pulfe was generally fujl, ftrong, and tenfe, in the beginning of the Fever, it was not, *a always fo. It was fometimes weak and low, but ftill J tenfe—if it be proper to ufe this term, to point out a condition of the pulfe, as it appears to me, wholly - peculiar to this Fever. I well remember that, in a youth of 12, or 13, years of age, the pulfe became much fuller after a plentiful bleeding ; though he was of a feeble conftitution, and had been flightly affected with the Fever once before.—In two gentlemen, who were confiderably affected by the fever, for'feveral weeks, but not to fuch a degree as to be confined to their beds, this peculiar pulfe was very diftinguifhable ; ' as much fo, I think, as in any other perfons whofe pulfe I examined. Hemorrhages, from various parts,of the body, were frequent, efpecially in the advanced ftage ofj- ■' the difeafe, and where it had been violent from the.>-) firft. Thefe were from the nofe, fauces, efpecially the {J gums, from punctures made in bloodletting, and from the ftomach : I faw no other. Bleeding from the | nofe and fauces often occurred in the beginning of, 3H the difeafe, and was removable by the general reme- ^ dies. Bleedings from the punctures made in blood- 1 letting, were feen in the clofe of the difeafe, and were reftrained with the greateft difficulty. I recollect to have been conftantly engaged in an attempt to re-. ftrain fuch a hemorrhage, in company with another phyfician, two of the moft melancholy hours I ever TO DR. W. BUEL. Il7 experienced. Hemorrhagy from the ftomach I fhall mention more particularly hereafter. II. Symptoms of pulmonic affection were not un- common ; though I do not recollect to have obferved them till the laft of September, or beginning of Oc- tober. They fometimes rofe nearly to the height of pneumonia. Hiccough was a troublefome fymptom, and often accompanied vomiting ; and there was fometimes, as it appeared tome, a mingled hiccoughing and belch- ing. III. The marks of congeftion in the brain were tod numerous and unequivocal to be miftaken.—A vio- lent pain in the head was one of the earlieft, moft conftant, and moft diftrefling, fyrnptoms of this dif- eafe---Coma was a very frequent fymptom ; and, as I thought, in proportion to the feverity of the difor- der. Towards the clofe, it amounted almoft to total ftupefaction; it being fcarcely poffible to roufe the patient. Some degree of delirium was common ; par- ticularly at the commencement of an exacerbation of the Fever ; manifefting itfelf in the hurried manner l\ in whichjthe patient performed any action, and in the rambling manner in which he converfed. That kind of delirium which fome have called light-headednefs, was remarkably prefent, in one perfon, at the clofe ; of his diforder. He often ftarted up, wildly, without any apparent object, then lay down, and commenced finging, in an interrupted, incoherent manner; but without any violence. And the day before his death, he continued to fing, with flight intervals, more than an hour.—At other times, he would fix on fome par- ticular words, and repeat them over, and over ; fome- times, with no appearance of emotion; at others, Il8 LETTERS FROM DR. E. H. SMITH, with fome glimmering of confcioufnefs.—In another perfon, a patient of a phyfician of my acquaintance, I the affection of the brain was like that in Phrenitis. J A bliftering-plafter applied, if I remember accurately, for 24 hours, to the head, which had been fhaven, excited no veffication, and fcarcely any rednefs, though twice the ufual quantity of cantharides was incorporated, and the patient was of a delicate ha- ?: bit. In this cafe the affection of the brain took place on the third day. and the patient died on the fifth or fixth.—On examination and diffection of the contents ■ of the cranium, all the membranes, and the very fub- M fiance of the brain, were difcovered to be in a remark- able and uncommon ftate of inflammation.—1 have been the more particular in relating this cafe, Ss it feems to contradict, in a degree, the ideas of Dr. Rufh, p. 50,of his Hiftory of the Philadelphia Fever : our feafon having been unufually wet. As connected with the ftate of the brain, it may be proper to mention here, that the eyes were often fuf- _ fufed, the whites of them tinged with yellow, and the fmall veflels turgid with blood. In fome patients they ■ had an expreffion of fingular wildnefs; while, in others, there was a remarkable vacuity, or abfence of - expreffion.—I faw no inftance of fquinting; nor ob- ferved any uncommon ftate of the pupil: but I ought A to acknowledge that my attention was not particularlvfllj directed to the condition of the eyes, in this refpect.™ The ftate of the mind was very variable. Some were exceedingly impatient and irafcible ; others, | aftonifhingly obftinate ; and this particularly, when, | as was often the cafe, there was a lofs of memory, or 1 fome degree of mania. A ftrong appeal to their good- \ fenfe, calling them by name, feemed to effect a tem- porary reftoration of their docility and recollection,— 3 TO DR. W. BUEL. Il8 which were foon loft.—Many were very confident, at firft,fuppofing their illnefs not be the Fever; but gave themfelves up to defpair, immediately on being convinced that it was the Fever. Many were full of dreadful apprehenfions, from the firft; and often- times, exceedingly aggravated what would have been, otherwife, a flight difeafe. A few, were calm, col- lected, undaunted, throughout their ficknefs. And here it may not be unfeafonable to remark, that thefe fame varieties were, in a degree, obfervable in thofe who continued well. Some phyficians thought they could difcern a tendency, among the citizens, gene- rally, to mania. It is certain that fear was a terrible evil, and frequently proved the exciting caufe of the Fever. IV. I have remarked that a great anxiety at theflo- machwas fometimes felt, on the patient's being firft feiz- ed with the Fever. Thk anxiety, it may now be added, in fome cafes, extended through the complaint; but was moft diftrefling when the Fever was moft violent. A great fenfe of forenefs was often complained of, when any thing was taken irfto the ftomach, as if it were raw;—to ufe the words of one in whom it was ob- ferved. In fome, the fenfibility of this organ was fo exceffive as to make it almoft impoffible to adminifter, either food or medicine, by the mouth. Patients were often afflicted with extreme pain-in the bowels; but more refembling that in dyfentery, than in cholic, A difcharge, generally, afforded a prefent relief. Flatulency, both of the ftomach and bowels, was almoft univerfal, and to an extraordinary degree.— The abdomen was fometimes diftended with wind ; R 119 LETTERS FROM DR. E. H. SMITH, ■but the diftenfion fubfi'ded after a conderable dif- charge of wind, downwards. This was often the cafe in one of my' patients. Several diffections, as I am informed by the gen. tleman principally concerned in them, fhew the fto- mach to have been in a remarkable ftate of inflamm*. tion and excoriation. It appears to me that this dif- eafe of the ftomach, or inflammation—(if it be pro- „, per to call it fo) extended through the whole length of the Alimentary Canal; as it is known to do in Apthac and fome other diforders; for one ij cafe of excoriation and partial mortification of the si Rectum came within my knowlege, and I have heard of feveral others. • ; I have mentioned, above, that Coftivenefs was al- moft univerfal at the commencement of the Fever ; but it was not always prefent* For though it was obfervable in the greater number of patients, fo much fo as to deferve to be ranked among the cha- racteriftic figns of the difeafej and though a conftant tendency to a coflive.ftate, w&s general in thofe fick with the diforder ; yet, in fome, the Fever was at- ■ tended from the firft, or for a while, by a Diarrhea; )B and in one inftance, the whole of the Difeafe ap- 1 peared to me to be turned upon the bowels, and to J be converted into, or affume the form of a Diar- I rhea. * Some were feized with vomiting at the firft, which' \ was foon flopped, or ceafed fpontaneoufly, and ne- ver returned. One cafe of this kind, proved favora- : ble—the patient recovering; another unfavorable, i the patient dying.—In others, vomiting commenced the difeafe, and continued through it: while in others, again, it came on in the courfe, or at the TO DR. W. BUEL* I 20 clofe of the diforder; and this both in fuccefsful and unfuccefsfui cafe3. V. The matters vomited up varied in colour and confiftence, in different perfons, and indifferent pe- riods of the difeafe. The moft. common was of a yellowifh, greenifh, or a muddy green and yellow, appearance, and very fluid. Vomitings of this kind, were feen both in thofe who recovered, and who died ; and were both temporary and continued.— Next, in frequency, was that of a blackifh appearance, commonly defcrmed as refemblirig coffee-grounds, but bearing a nearer refemblance to blood partly burnt, and diluted with muddy water. Several who had this vomiting recovered.—-I never faw an inftance of that tar-like vomit, which has been noticed by fome writers. But, of all others,, that which ftruck me as evidential of the greateft derangement of the ftomach, was the vomiting up of, what appeared to be, thin blood, in which floated a flaky, filmy fub- ftance, which. I fuppofe to have been the villous coat of the ftomach.—This I faw but in a fingle inftance, a few hours, before death. This difcharge was fre- quent,, though fmall; and accompanied by a large worm. I cannot help thinking that the matters vomited: up, except it be thofe of the yellowifh or greenifh caft, have all a portion of blood mingled with them;, and that their various appearances depend—afide from their mixture with .the contents of the fto- mach—in great meafure, on the quantity of blood mingled with them. - It appears to me that, in this difeafe, the fecretion of the Bile is greatly affected; and that, in many inftances, the blood itfelf paffes into the biliary.veffels, .charged.with the Bile, de- figned to have been feparatedj and being poured in- 121 LETTERS FROM DR. E. H. iMITII, to the duodenum, and difcharged by flool or vomit- ing, communicates the blacknefs obferved in thofe evacuations. Befide this, as appears from diffection, and from the cafe juft mentioned, the coats of the ftomach itfelf are deftroyed; and the numerous little veffels, which, in a healthy ftate, diftill into it a limpid and colourlefs fluid, now are preternaturally diftended, receive the blood, inftead of lymph, and pour it, by their numerous orifices, into this organ. This effufion of blood may be fuppofed to increafe, as the difeafe increafe's in violence, till, at length, the tender coats of the ftomach are feparated, and.thrown up, mingled with pure blood.—If thefe ideas be juft, it is clear that no vomiting can b^ more evidential of a fatal termination of the difeafe, than this; none can afford a more unequivocal fign to the phyfician, that his attention is no longer ufeful*. The difcharges from the bowels were very dark, in general, even where no preparation of mercury was ufed. They were, likewife, in moft cafes, re- markably fluid, where the bowels had been once. * If the ideas contained in the above paragraph are accurate, they will tend to confirm both the general notions of the difeafe,, and of the proper mode of cure, advanced in thefe letters. For— ift. The effect of Blood-letting, in flopping the blach-vomt, may be explained on the fame principle as in Hemoptoe—by* weakening the circulation, and allowing time for coagulation. 2d. The reafon why all ilimulating fnbftances increafe the particular difcharges from the ftomach, is evident; and, alfo, why cold drinks, ice, &c. reftrain them. 3d. The aftonifhing fluidity, or difTolution, as it is called, of the Hood is accounted for, and feen fairly to correfpond with the preceding circumftances: all of which— 4th. Demonftrate the nature of this difeafe; that it is not a difeafe of vafcular debility:—and eftabliih the propriety of em- ploying evacuations, and whatever may lefTen the aftivity of the circulations, to effe€t a cure. TO DR. W. BUEL. 122 thoroughly, opened ;and, where the purgatives were brifk, and in all fevere cafes, exceflively offenfive.— They were, fometimes, of a dark, fhining appearance, fomewhat like moiaffes, melted pitch, or black-lead. But I have feen ftools of this colour, in other dif- eafes—particularly once in the Croup—where calo- mel was frequently ufed as a purge.—I mention this, as it may fometimes happen, that phyficians deceive themfelves, in fuch cafes, afcribing that to the difor- der, which depends on medicines. Some were troubled, with a retention of urine ; but, more generally, with an unufual flow ; and this in one inftance, I diftinaiy recoiled, where the quan- tity of fluids taken into the body, was very fmall. In refpect to fweating, I difcovered nothing uni- form. In one cafe, the patient always had a profufe, clammy, fweat, when he fell into a reftlefs fleep, with a rife of fever. This was often obfervable, likewife, in that ftate of remarkable anxiety which frequently preceded an evacuation by ftool. Blood drawn in this Fever, was remarkably'want- ing in floridity ; and this was efpecially true of that which was evacuated in the clofe of the difeafe—, whether by art, or fpontaneous effufion. In one in- ftance it feemed endowed with a cauftic quality, and affected a lancet fo as to leave a permanent inequality and difcolouration of its furface. VI. Sleep, for the moft part, appeared unnatural and unrefreihing; attended by great reftleffnefs ;and fometimes by great mobility of the mufcles, twitch- ing of the tendons, and frequent flarting up. One of my patients often raifed himfelf up, fuddenly, out of bed, with every appearance of extraordinary ter- J 23 LETTERS FROM PR. «• H. SMITH, ror ; but with no evident or clear confcioufnefs of the act. In one perfon, I faw remarkable fubfultus tendi* num. There was great variety in mufcular power, in difc ferent perfons. A man who died with the very worft fyrnptoms of the Fever, the evening before his death, rofe from his bed, ran down two flights of flair?, re. turned, and was only prevented from going down a fecond time by his nurfe's having locked him in his I chamber.—In another cafe, where the difeafe was \ mild, the patient felt perfectly eafy and compofed, . and in full pofleffion of mental and corporeal ftrength, while he lay on his bed ; but, when he rofe, and at- tempted to walk, a fenfe of univcrfal anxiety was felt, his ideas became confined, his ftrength feemed to de- fert him, a fudden faintnefs came over him, and twice he funk down, unable to proceed. An evacuation, by flool, often fuddenly reftored the patient, who was lifted from bed, to fuch a degree .of ftrength, that he continued for fome time after, to walk about the room, or fit up; VII. I noticed no uncommon fenfibility to light { but in a fingle cafe; and that was not of long dura- ' tion. Hearing, in one inftance, I obferved to be unufually;B acute ; but generally, it was much impaired i and, iH fometimes, feemed to be entirely loft. Perhaps this may account for the apparent lofs of memory in fome \ perfons. '1 The tafte was either exceedingly impaired, or very fickle. The fame may be faid of the appetite. When ^ the appetite began to return, and food to be relifhed, TO DR. W. BUEL. 124 the fick were very voracious, but not eafily fuited. They difcovered no partiality for animal food. Thirfl was moderate, in a few inftances; but oftener excef- five. I have feen Porter defired ; but it was not often relifhed, when allowed. The fame is true of coffee. Water was, univerfally, the moft agreeable drink y and I allowed its free ufe. One of my patients fre- quently drank, in one night, when very feverifii and reftlefs, three quarts of water. The appearance of the tongue varied, according to the violence and du- ration of the difeafe, from white, to yellow, darkifh, and black, like burnt blood ; and the gums often af- fumed this laft appearance, when there had been bleeding from them. An aftonifning infenfibility to cold was nearly univerfal.—I remember, in one of thofe cold turns which we had in September, a remarkable inftance of this. One of my patients occupied a chamber in the fecond ftory : the room was very large, extending the whole width of the houfe, and having a chimney, a large door, and two windows at either end. The bed was hard, in the. middle of the room, the door and all the windows open, and he covered with a fingle fheet, frequently thrown off in his reftleffnefs, yet he complained of no cold, while I was chilled through, though fheltered from the draught of air, with my ufuaf cloaths on, and the addition of a fur- tout and double cloak. VIII. Yellownefs of the fkin was not conftantly prefent in this difeafe ; at leaft, not in any remarkable degree. A tinge of it was common ir the eyes and on the fkin ; but not ftronger, in numerous inftances, than in ordinary Fevers. Some were exceedingly yellow, even to being tawny—fo that the bed and body linen were ftained, both by the fweat and urine. I2J LETTERS FI'.OM DR. E. H. SMITH, I faw eruptions but in a fingle inftance* They re- fembled mufketo bites fo nearly, that, had I not been forewarned of this fimilarity by Dr. Rufh, in his ac- count of the Philadelphia Fever, I fhould have mifta- ken them, efpecially confidering the numbers of thefe animals.—In this inftance, the eruptions were on every part of the body ; which had not been expofed to their ravages. i I have fometimes obferved a coldnefs of the fkin, I on the body, generally, but efpecially of the feet, of which the patient was unconfeious, while the face fl and breaft were red and communicated a burning I fenfation to the touch. I IX. I have, hitherto, faid nothing of the type o( 1 the Fever of 1795; and, in truth, it is a point on I which I could wifh to be filent, as, of all others, con-. J nected with the Fever, it is the one where my obferva- I tion is the Idaft fatisfactory. In its mildeft form,theFe- I ver or pyrexia, appeared to me to be moderate and conftant; without any evident or ftrongly-marked#<« exacerbation : when fevere, it fell in with Dr. Cul- I Ien's idea of a Continued Fever, as ftated in his Firft j Lines § 27, more than with any other: but, in both Jm cafes, I could not determine that there was any regu-",*jj| larity in the rife, or diminution of pyrexia ; on theJ3 contrary, the remiffion (if it be proper to term it fo)"j9 was more or lefs protracted, and the exacerbationJBB fooner or later, moderate or fevere, in proportion as ^| the patient preferved a regular ftate of body and 7| mind, or was irregular in thefe refpects. For exam- ■ pie—any fudden agitation of mind, as anger, pertur- 1 bation, &c. and any irregularity of body, fuch as eat- I ing improper food or too much food, drinking any iHmulating drink, reftleffnefs, too long detention of t>.j faces, &c. appeared to hurry on a return of all TO DR. W. BUEL, I27 the violent fyrnptoms ; while, on the other hand, the fick never failed to get through the day with more eafe to themfelves, when no fuch excefs, or irregula- rity, happened. In one cafe which came under my care, and which various caufes contributed to render the moft inte- refting of any I attended, there were complete inter- miffions, during a part of the diforder ; but there was no kind of regularity, either in their commencement, or duration ; and a flight excefs, in any of the parti- culars mentioned in the preceeding paragraph, was fufficient to bring on a fpeedy and violent turn of Fever. X. The period of convalefcence, as well as of Fe- ver, was variable. In the former part of the time, and before the weather began to grow.cool, patients fel- dom died after the tenth day—as far as I can learn ; but their deaths took place on the 3d, 4th, 5th, 6th, 7th, rarely on the 8th, and ftill more rarely on the 9th day. After the cold weather appeared, they fometimes dropped off fuddenly, and after having ex- hibited all the marks of convalefcence, three weeks from the time of their feizure.—So, of thofe who re- covered, fome regained their health with an elaftic ( quicknefs ; while others, were very flow in the ac- quifition of ftrength; were a long time troubled with great weaknefs in fome of their joints, and ofteneft the knees ; and were afflicted by cedematous ^fwellings of the feet, ancles, and legs. y"■' You have now before you the refult of my obfer- vations, on the appearances of the Fever of 1795 ; and I fhall conclude this letter by the fimple men- S 128 LETTERS FROM DR. £. H. SMITH, tion of two facts, which will ferve to confirm the doctrine of the great Sydenham, concerning the defpotic nature of the reigning ficknefs. The Meazles had begun to appear, when the Fe- ver came, and they difappeared; but no fooner was the Fever vanquifhed, than they returned more generally than ever, and have continued in this city ever fince.* I cannot learn that any febrile difeafe was obferv- ed in the city, while the Yellow-Fever was prefent. J I faw only one inftance of Intermitting-Fever in a lady, who contracted it in the country. It was flight, and was foon cured on her coming to town, by the ufual remedies. Her refidence in town, like- wife, was in a part to which the Yellow Fever never came. Befide this, I heard of one other inftance, of a gentleman coming hither, from fome other place, with the Fever and Ague ; which was, alfo, cured by the ufual means. I fhall proceed, in my next letter, to bring you ac- quainted with thofe means which were moft fucceff- ful in the removal of that difeafe which I have juft defcribed. LETTER NINTH. Method of Cure, in the Fever of 1795. It was obvious, to the flighteft obfervation, that the miidnefs, or feverity, of the Fever of 1795, de- pended, in no fmall degree, on the fituation of the * April. TO DR. W. EUEL. 129 patient. That thofe who lived in the higher, drier, cleaner, and more airy parts of the town, were more lightly affected ; and that a removal, from the other quarters, into fuch as were fo circumftanced, was al- ways followed by beneficial effects to the perfon re- moved. In confequenee, a milder treatment, in every refpect, efpecially a more fparing ufe of evacuations, was warrantable in fome cafes, than in others ; and as fome practitioners were chiefly employed among thofe whofe favorable fituations protected them from the moft malignant attacks of the difeafe, you will readily conceive why there fhould prevail, in the minds of fome, an opinion that very active remedies were unneceffary, and a recurrence to the lancet in- expedient, at leaft, if not pernicious. It is true that I did not always ufe it myfelf; but it is alfo true, that I never failed to regret the omiffion. And though I loft no patient by the neglect, yet I am convinced that, in every fuch cafe, however flight the difeafe might appear, the cure was protracted. But, if the remedies were not always the fame, the principle on which they were adminiftered, was uniform; and their operation the fame in kind, if not in degree.— And, after the Fever became more general, and the feafon confiderably advanced, there was but little choice left in the ufe cf means. Pofitive and fpeedy relief was required ; for to temporize, was to kill.— You will fufticiently comprehend, from thefe re- marks, how far the practice recommended below admitted of variety in the application ; and I fhall de- tain you no longer from the confideration of the par- ticular remedies, which are meant to be arranged nearly in the order of their comparative importance. I. Blood-letting.-—This was indicated by the fevere pain, heat, and rednefs, cf the head and countenance ; by the redaefs, turgefcence, I'3<3 LETTERS FROM DR. £. ili SMITH, and heavinefs, of the eyes ; by the oppreffion, .piin, and anxiety, often obfervable at the breaft; by the fullnefs, hardnefs, tenfity, or oppreffednefs I of the pulfe—and equally by that flender, wiry, vermicular feeling which it fometimes had—commu*. j| mcating an idea of approaching numbnefs to the finger ' which felt it.* * ■ The effects of bleeding were, in every inftance where I had an opportunity of obferving them, moft falutary. The fick feldom failed of finding immedi- ! ate relief from it, and of perceiving that relief in- creafed as the blood continued to flow. It diminifhed the pains in the head, breaft, and ftomach: oppref- fion, anxiety, faintnefs, and heat, were moderated : the eyes rarely failed to aflume a clearer and more natural appearance : and it feemed to communicate a new energy to the fyftem.—I remember an inftance where a patient was fo unable to affift himfelf, on the fecond day of the difeafe, that, when I wantec^ to bleed him, it required two perfons tofupport him, in paffing a few fleps from his bed, into the open air.— There, he was feated and fupported in a chair. He grew eafier, in every refpect, as the blood flowed.— After taking away about .twenty ounces, and tying up his arm, he rofe without affiflance ; walked feve- Jj ral rods, to a Neceffary ; took care of himfelf; had a Jfl profufe evacuation, by which he feemed to gain addi- fl tionaf ftrength ; and returned to his bed, without any •■ aid, and with a firm flep. ■ Such were the immediate effects of bleeding early in the difeafe. The importance of this remedy was \ not diminifhed by the duration of the diforder, nor * It is fearcely poffible to convey an idea, by words, of minute peculiarities in the pulfe. You will recoiled this, and pardon rnc, if I have failed in thio inftance. TO DR. W. BUEL. I3I the neceffity for it leffened, while the fyrnptoms con- tinued which made it ufeful in the commencement.— On the contrary, it was oftentimes as requifite, and as beneficial, the fifth and the fixth days, as on the firft. But this neceffity for its ufe, at fo late a period, did not often occur, where, it had been vigoroufly em- ployed, in connection with other remedies, at the firft. The following cafe, which I ftate briefly, k one among numbers, in evidence of the advantage cf early, free, and repeated bleeding. A phyfician was called to a young man, with all the fyrnptoms of the difeafe—as it generally appeared at the firft—in the evening. He bled him 16 or 18 ounces; directed purges, &c. in the manner hereaf- ter to be mentioned ; and though the weather was then cool, ordered the windows to be removed, both day and night. The fyrnptoms were relieved ; but the next morning it was thought neceffary to repeat the bleeding; which was done, to an equal quantity. The purges, &c. were alfo continued. In the even- ing, a third bleeding was performed, and a like quan- tity of blood was taken away ; and the other reme- dies were continued. On the ninth day, from the feizure, the man was well, and able to purfue his bu- finefs ; though his ftrength was not perfectly ref- tored. In one inftance which came to my knowledge, bleeding removed an obftinate vomiting, of many days continuance, which threatened the life of the pa- tient, and which had refifted all other remedies. It feems hardly neceffary to add any thing more, in favor of this remedy, after it:? beneficial effects have 132 LETTERS FROM DR. E. H. SMITH, been ftated, with fo much eloquence and perfpicuity, by Dr. Rufh, in his various publications, refpecting the Yellow Fever. II. Purging. No cafe occurred, in my particular , practice, where, not with (landing the vomiting, ca- j thartics could not be adminiftered. When this fymp. * torn was very troublefome, they were required to be J given in a folid form, at more confider able intervals, » and of as fmall a fize as poffible. The activity of i the purge was always to be proportioned to the vio- lence of the fyrnptoms ; and it was important that all medicines of this kind fhould be given in divided ' dofes—fo as to promote a gradual and continued dif- charge.—The operation was often very much affifted by clyfters ; for which water alone was neceffary. The good effects of cathartics were not lefs obvi- ous than thofe of venaefection. They were indicated by the conftipation, fo generally prefent; by pain in the bowels, flatulency, and tumefaction of the abdo- men ; by pains of the head, heat and flufhings of the face, and of the whole body ; and finally, by the vo- mitings : and all thefe fyrnptoms they rarely failed to obviate, or relieve. This relief, too, was oftentimes fo fudden, as to feem like enchantment.—Frequently ] have I feen a patient, after an hour or more of fevere pain, reftleffnefs. heat, thirft, and inquietude of every *■ kind—feeble, exhaufted, and as it were, ready to ex- *■ pire—rife with the greateft difficulty, and with the | aid of others, t6 the chair, and after his evacuation, ^ feel his pains removed, his heat and reftleffnefs va- 1 nifhed, his ftrength renewed, and hinuelf able to fit up, or walk about, and breathe the air with freedom: | and fometimes, the difcharge was followed by a re- ffefhing fleep, and gentle perfpiration. TO DR. W. BUEL, »33 - Thefe benefits were neither fo certainly, nor fo fre- quently, obtained, where the evacuations were violent and fudden. Indeed, it appears queftionable to me, whether it be ever proper to excite fuch difcharges, in Fevers. Patients, when much reduced, are apt to fink under fuch immediate and abundant evacua- tions. III. Cool Air.—It was of the utmoft importance to procure a conftant application of cool air to the body of the patient, from the commencement of the Fever. The advantages which refulted, were univer- fal and wonderful.—To this end, the fick were or- dered to be placed on a hard bed, with very little covering, in the middle of the room ; and the doors and windows were, as much as poffible, kept open day and night.—The good effects of this practice were exceedingly increafed, where the application of the cool air could be made to the patient in an erect pofture. For, not only was it more equable, but the head was alfo relieved, thereby, from that fenfe of fullnefs and oppreffion vvhich was invariably experi- enced in a recumbent pofture. The fick, therefore, were directed to fit up, in the courfe of the day, with the afliftance of their attendants, as long as their ftrength would permit, without their becoming ex- hausted. While in this fituation, their feet and legs were covered more warmly than any other part of the body : and if cloths, dipped in cold water, or vinegar, were often applied to the temples, the relief obtained was ftill greater. •" IV. Cool Drinks.—The great thirft, which was nearly univerfal in this Fever, from the firft, made the drinks, of nece|fity, an article of early attention. It was obfervable that they never could be too cold. Pa- Ij4 LETTERS FROM DR. E. H. SMITH, tients complained of the warmth of water which had been Handing but a fhort time; and feemed to j languifh for a fupply of frefh water, with an anxiety j which became truly painful, when the ufual hour of 1 its diftribution approached.* ] The good effects of a plentiful ufe of cool, dilut- j ing drinks, were obvious. They tempered the pre- i ternatural heat and anxiety of the ftomach ; often re- ! {trained vomiting, and the faucial hemorrhage; ferv- ed to dilute, and carry off, the offenfive contents of the inteftines ; and difpofed to a more equable and aqueous fweat.—Of all other drinks, Water was moft i relifhed—and on many accounts, was the moft pro- per. A pleafant and fuitable drink was made, by pouring warm water on frefh apples, and fuffering it to cool; and likewife,' by the addition of a piece of toafted bread to water. Milk, much diluted with water, was relifhed by fome; fome were fond of but- ter-milk ; and as all thefe poffefled bland and nutriti- ous, qualities, they were advantageoufly ufed, where a variety of drinks was required by the capricious tafte of the patient. ■ I had no opportunity of trying the effiacy of ice, « but the teftimony of a Phyficianf^in whofe judgements™ and veracity I place great confidence, is ftfongly in its-favor, and inclines me to believe that it may be' ■ ufed with high expectations of advantage. Under fl his direction, it anfwered, better than any thing elfe,' fl in relieving heat and fever; reftraining hemorrhagy $f * The water which is ufed for drinking, in this city, is moftly drawn from a fingle pump, called the Tea-Water Pump ; and it is diftribute.1, by means of large calks, which arc carted to every part of the town ; once a day, in winter ; and every morning "and afternoon, in fummer. TO DR. W. BUEL. '35 and obviating, partially, or entirely, the vomiting- even the black vomiting. V. Cleanliness.—This is of the utmoft impor- tance, and, in a meafure, indifpenfable.—The bed and body linen fhould be often changed ; the cloaths neceffary about the bed, well aired, feveral times a day : there fhould be tv/o beds, one of which may be aired, while the other is in ufe: all unne- ceffary furniture—particularly woollen, filk and cot- ton—every thing which may abforb and retain efflu- via and moifture—fhould be removed: all utenfils employed about the patient, frequently changed and rinfed : the room mould be often fprinkled and dufted : the face, mouth, eyes whole head, hands— and, where it can be done, body of the patient, wafhed with cool water, feveral times in the day. The more exactly—other circumftances being regarded—thefe directions can be put in execution, the better for the patient; and, as my own experience convinces me, the more certain and fpeedy will be his recovery.— You will obferve that I fay cool water ; for I cannot believe that the fhock which would follow from the application of cold water to the body, would be be- neficial.—It is not here, as in the ufe of air ; for water is fo much more perfect a conductor of heat, that the abftraction would be univerfal and fudden, were it applied cold. And, befide, as much is effected per- haps, by the ablution, as by the coldnefs, confequent upon bathing. It was not in my power, in any cafe, to carry this practice to the extent I wifhed ; but, ceteris paribus, the relief of the patient was proportioned to the de- gree in which it was purfued. T 136 LETTERS FROM DR. E. H. SMITH, VI. Blisters.—The advantages ufually derived , from the ufe of blifters, were not evident. It was fometimes doubtful whether they were any way j ferviceable. Yet there were inftances in which J they afforded relief; though moftly temporarily.— I I have feen them, applied to the breaft, relieve 1 the oppreflion at the lungs ; and applied to the j back of the neck, relieve the head : in both cafc$, when the difeafe had been of fome days continuance. ' A phyfician, to whom I mentioned thefe remarks, in- formed me that his experience juftified them, except .i when, as was often obferved by him, a hemorrhage enfued from the vefication, and continued for fome days. Perhaps it was neceffary to the efficacy of blif- 1 ters, that they fliould have been, always, preceded by copious blood-letting. VII. The Tindura Sacra, given in fmall quantities, at intervals, in water, was found by one Phyfician, ^ to have the happieft effects, in relieving naufea, and obviating the tendency to vomit, in all cafes where a deftruction of the coats of the ftomach had not taken place. The fame gentleman derived much advantage over the difeafe, where, from long-continued vo- •' miting and effort to vomit, the ftomach appeared to have fuftained confiderable injury, or abrafion, from the ufe of 01. Oliv. vel amygdal. dulc*—The oil co- ) vered the inflamed, or abraded, part, and protected it from mechanical flimulus, while it allayed the forenefs i and irritation produced by the action of the difeafed fluids it contained. : VIII. Food.—1 have before remarked that the fick * fhewed no preference for animal food ; oft the con- trary, they very generally refufed it. Some, -who requefted it to be prepared for them, found themfelves TO DR. W. BUEL. ■137 unable to eat it, when prefented to them.-—Fruits, milk, bifcuit boiled in milk or water, fago, falep, hafty-pudding, and vegetable food, generally, were moft reliflied by them, both during their illnefs and their convalefcence.—This was peculiarly fortunate, as any indulgence in a contrary courfe, was fure to be followed by diftrefling effects. The more rigidly attentive patients were to preferving a fimplicity of diet, the more certain and pleafant was their recovery. And, in all cafes that I had opportunity to obferve, their convalefcence was always extended or lhortened, tedious or fatisfactory, in proportion as they returned fuddenly to the ufe of meats and ftimulating drinks, or adhered to vegetable food and water. I have now, my dear friend, made you acquainted with that courfe which I generally purfued, in regard to thofe who came under my care. The number was not great, nor the fuccefs always complete—for I had not always the liberty of employing the means I wifhed to, as fully and freely as was neceffary to com- plete fuccefs. But, I can truly fay, that I never faw them do injury ; and that they appeared to me to do good, in every cafe, where they were employed, and in the proportion of their trial and application.— More than this no man can truly declare; more than this ought never to be expected from any remedies. The znoft able practitioners are deftined to fee their patients frequently expire, in fpite of all their care, through the obftinacy of the patients themfelves, and the prejudices of their friends, the careleffnefs of at- tendants, or the intervention of unforefeen and una- voidable accidents. The confciofunefs of having done their duty, of having acquitted themfelves, under cir- I38 LETTERS FROM DR. E. II. SMITH, cumftances fo diftrefsful and embaraffing, to the beft of their knowledge, and with purity of intention, will prove a never-failing confolation, though the execra- tions of ignorance, and the calumnies of hatred, may purfue and perfecute them.—Happy,—at leaft in this refpect,—are thofe, " the peaceful tenor of whofe way," while it excites neither oppofition nor malice, and neither elevates to opulence nor fame, fecures them from mifreprefentation and injultice. LETTER TENTH. Mifcellaneous remarks on Medicines ufed as Remedies in the Fever, and general conclufions. You wifh to obtain every poffible information, reflecting the Fever of 1795 ; you are not fatisfjed with knowing what remedies I employed, nor which were moft fuccefsful; but you would learn all that were ufed; the fuccefs, or failure of each. I ap- plaud your curiofity, my friend, for I am not ignorant of the benevolent motives which excite it; but I fear that there is little with which it is in my power fur- ther to gratify it. The practice which I faw, was that which I have recommended: other remedies I: know were ufed; but, not having had opportunity, but in few inftances, to mark their effects, I ought not, from my own convictions, how well-founded foever they may appear to me, precipitately to con- demn either the prescriptions, or their authors. In the variety of cafes, conftitntions, and circumftances, it might happen that fome of thofe very things, which TO DR. W. BUEL. ' 139 appeared pernicious when I faw them ufed, were fometimes proper and falutary. It would be pre- fumptuous, therefore, in me, to decide without more information ; but I may be allowed an opinion ; and that opinion need not be with-held from a friend.—I confefs, then, that from the fuccefs which attended the antiphlogiftic plan of cure, I am perfuadH that no other can be falutary, or fafe ; and the fe"* in* ftances in which the effects of a different mode of treating the Fever were obferved by me, ftrengttk aed my previous convictions of its inutility and dan- ger. The medicines chiefly trufted to, by thofe who purfued a different courfe from that laid down in the preceding letter, were, as I am informed, Calomel, to promote, or effect a Salivation,—Bark—Lauda- num—Wine, and other'ftimulating drinks—with an Animal diet. Of the effects of Salivation, not having feen it take place, by nature nor art, in the Fever of 1795, I can fay nothing. Dr. Rufh countenances the practice,' in his Treatife on the Fever of Philadelphia, and adds the teftimony of many refpectable authorities to his OWn.—As a Cathartic, Calomel, combined with other purgative fubftances, was unqueftionably ufe- ful. Some, I know, thought otherwife; andthat other purgatives might be more fafely and efficaciouf- ly employed; and, I confefs, I faw fome cafes in which it appeared to affect the ftomach very painful- ly. But a Phyfician on whofe judgment I have great reliance, informs me, that he faw reafon to re- ject a fimilar opinion, which he had haftily adopted ; repeated obfervation having convinced him, that all the fyrnptoms of gaftric affection were worfe in thofe 14© LETTERS FROM DR. E. TL SMITH, who had not been purged with Calomel, than in thofe who had been evacuated by its affiftance. I gave Bark, in no form, but in three cafes. Two were in the early part of the reign of the Fever, the two firft patients that I had; and I am convinced it retarded the cure in both. In the other inftance, it was «wlminiftered after the Fever had left the Patient, and he was convalefcent. Here it was given as any other Bitter, and as much in compliance with his opinions, as from any expectation of its doing good; and, as far as I can judge, with very little effect of any kind.—In the following cafe, its exhibition was not fo harmlefs. A medical friend was called to vifit the patient of another Phyfician, who had /quitted town, on account of his health. The fick man was oppreft by the moft alarming fyrnptoms; of the number of which, were hemorrhagy and the black vomit. The ftimu- lating fyftem had been fteadily purfued, and was con- tinued, under the direction of a pupil of the phyfician^ firft employed. In particular, large quantities of Bark were exhibited, throughout the day.—On the entrance of the fecond phyfician, the Bark and all other medicines of the kind, were laid afide; cool air was freely admitted; and the antiphlogiftic plan of cure ftrictly adhered to. The confequence was, that all the fyrnptoms were relieved, and a profpect opened on the patient of a recovery. The vomiting and hemorrhagy had totally ceafed. In this fitua- tion, and while the Phyfician was attending to fome perfons whofe condition was more alarming, the perfon who had the immediate charge of the fick man, began, again, to adminifter the Bark.—The next day —or the very fame, at night—all the bad fyrnptoms TO DR* W. BUEL. 141 recurred ; the Bark was, neverthelefs, perfifted in j and the man died. Several fimilar cafes have been reported to me; but none fo minutely as to authorize an attempt to ftate them to you. The extreme reftleffnefs of a patient, in whom I had the ftrongeft intereft, and for whofe fate the deepeft anxiety, induced me, in violation of my more fober judgement, to adminifter Laudanum.— This I did not do, till he had fpent three nearly fleep- lefs nights.—In every inftance, it undoubtedly, in- creafed the reftleffnefs, clammy fweats, thirft and Fever. I was obliged to difcontinue it. Wine, brandy and water, and efpecially porter, when taken by any of my patients, had the moft per- nicious effects. I had occafion to fee an accefs of Fever, repeatedly brought on by the one, and a re- lapfe by the other; where they were ufed without my knowlege, and contrary to my direction. Of the effects of Animal Diet, I have already fpoken, and have nothing new to add. On the whole, it appears inconteftible to me, that what is called the antiphlogiftic treatment is to be adopted in Fevers like that which prevailed in New- York, in 1795, in all its ftrictnefs, and adhered to with pertinacious refolution. Both the fymptoms of the difeafe, and the fuccefs attendant on the practice recommended, concur in eftablifhing the propriety of employing it.—It is ajfo to be remembered that, in this difeafe, not a moment is to be loft : a day, an hour, nay almoft an inftant of delay, may fometimes be fatal; and the means practifed muft be powerful in proportion to the violence of the fymptoms. Nei- I42 LETTERS FROM DR. E. H. SMITH, ther muft we be deceived by the apparent mildnefs of the feizure—for a few hours may entirely change the face of things, and we may be left to lament that credulity which led us to temporize, and prevented J the ufe of thofe remedies, which delay alone rendered 1 ineffectual. 1 But, while the Phyfician ftrenuoufly directs his ef- i forts to the removal of the fymptoms of this difeafe, let him not overlook a paffion which never fails to aggravate them. Fear, the exciting caufe, in many in- ' ftances, of the Fever; the fomenter of all its evils ; and fometimes, as it were, the fole difeafe ; is a fre- i quent and dreadful calamity, and one of the direft adverfaries with which medicine has to contend.—Iri numerous inftances, during the continuance of the Fever of 1795, apprehenfion touched upon infanity; deftroying all confidence in the Phyfician and in re- j medies,or exciting an abfurd and enthufiaftic reliance i on pretenders and madmen : and utterly difqualfying the patient for a proper attention to himfelf.—In the ; well, the evil was fcarcely lefs. The name, alone, of Yellow Fever, feemed fufficient to induce difeafe, to banifli discretion, to fever the bonds of focialconriec- tion, rend afunder the ties of parental, filial, and con- ^ nubial affection, and put reafon to flight.—It was in jl vain to point out the folly of this terror; to declare M the difeafe not infectious, and eafy of prevention ; to fl offer mathematical demonftration that other diforders fl were often more mortal, without exciting any alarm ; it was ftill the Yellow Fever, and that was an irrefi- I liable reply to every argument.—The city of New- ■ Haven, fummer before laft, loft about 50 of its inha- i bitants, with the Yellow Fever. Univerfal confter- j nation prevailed throughout: the place ; all bufinefs j was at an end ; and moft of the principal inhabitants J fled.—Laft fummer, the Dyfentery raged there : more _ TO DR. W. BUEL. *43 than 70 perfons died of it: but nobody fled; nobody was frightened ; and the Magiftrates, very gravely, put a flop to all communication with New-York, for fear of the Yellow Fever; made veffels ride qua? rantine, and confined ftage-coach paffengers, that no ' contagion might be diffufed, through the city, from their trunks and their garments.-t-But, it is time to put an end to this feries of letters; and feek, by no- velty, to give new intereft to our correfpondence. I fhall take my leave of the prefent fubject, with an enumeration of the inferences I have drawn from > having viewed it, in the light here exhibited to you. 1. The Fever of 1795 was Endemic :—i. e. gene- ' rated by local caufes, producing a Fever every year, in this city. 2. The peculiar ferocity of the Endemic of New- York, in 1795, is afcribable to the peculiarity of the feafon, together with a greater accumulation, than ufual, of the ordinary caufes. 3. It was not Contagious: i. e. communicated by contact of difeafed perfons, by cloaths, nor by vifiting the fick, &c. 4. As it originated here, its prevention will depend on a change of the local and individual circumftances which promote it. 5. The Fever in 1795, exhibited fuch appearances as characterize what are cuftomarily denominated In- flammatory Difeafes. 6. It is cured by the remedies fuited to remove In- flammatory Difeafes. U J44 LETTERS FROM DR. E. 11. SMITH. -. The fame caufes which converted the ordinary Fever of New-York into the Yellow Fever, would change the Fever which prevails around our Wef- tern Lakes into the Yellow Fever ; and, as certainly, the Intermitting Fever of Sheffield : while the efta- blifhment of a free ventilation, the filling up of all pools, vards, &c. and a fcrupulous attention to clean- linefs and fimple diet, would reduce out Fever to a fimple Remittent or Intermittent, or remove it alto- gether-, as the filling up and cultivation of your ponds and marines, would forever banifli all Fevers of the kind—as general difeafes—from Sheffield* I have now, my dear friend, performed the talk demanded of me, in the heft manner I am able con- liftent with my leifure, and my duty towards others. i cannot conclude without once more foliciting your indulgence, and requefting you to recollect with what expectations and confeffions I entered on the compo- fition of thefe letters.—I have taken the words of Cicero for my motto— " Rationem, quo ea me cumque ducetfequar—" And if I have erred in my conceptions of what is reafon, and what was fact, let my intentions prove mf\ ar-ology. 8. 7C. zfmitL LETT E R from DOCTORS TAYLOR AND HANSFORD, TO THE PUBLISHER. LETTER FROM DOCTORS TAYLOR AND HANSFORD/ TO THE PUBLISHER. NORFOLK, VIRGINIA, DECEMBER, 1795 SIR, If, in our attempts to add to your information reflecting thefever, which prevailed here in Auguft laft, we fhould draw upon us the illiberal farcafms, which we have obferved to attend all who endeavor to ferve their fellow creatures in this way, we muft leave it to you to juftify our intentions, at leafi% be- ing ourfelves unprepared to anfwer any thing which may be objected to what we fhall advance. We mean to ftate fads, or what we believe to be fuch^ and willing to admit that there are feveral ways of curing the fame difeafe. It will not be underftood, that we reprobate the practice of others who follow a different mode of treatment. Our obfervations have been drawn from thirty years experience, with the advantage of records relating to fimilar difeafes for a muchlonger period. We do not know of a more regular mode of treating the fubject than by anfwering your inquiries in the order they occur, vhich will perhaps comprehend every thing required at prefent. I48 ACCOUNT OF THE FEVER IN NORFOLK. The Fever we believe has its origin in the feafon,, and exifts every year in various grades, beginning generally in the month of Auguft, and difappearing. about the middle of October. The precife time of its commencement and termi- nation, and its degree of malignancy, depending upon contingent caufes. Vv e have been accuftomed to call | it a Bilious Remittent, with a tendency to putrefac- tion ; whenever it proves uncommonly fatal, it is aggravated, according to the beft of our obfervation,. by the prevalence of fome unufual weather for a long time together—Thus we have feen this difeafe equally malignant after a dry hot feafon, and after a very rainy period. The approach of frofty weather being uniformly the cure for the effects of either.-— j The Fever of the laft autumnal feafon, appeared firft I on the river, then on the ftreets adjoining ; was foon ] after diffufed through the town and fuburbs, and ] finally the neighboring country ; though in this laft j not generally : as ufual it declined on the approach of i cold weather.—The month of June had been very cool, and at the change of the moon, or a little be- ,( fore, it began to rain in torrents, and fo continued to do, with fhort intervals of clofe fultry weather, till 1 Auguft, when a violent hurricane, attended with a I flood of rain, laid wafte the whole vegetable kingi. d dom—afterwards the weather was as before, fultry*;'« and moift, with profufe fhowers till the end of Sep* l| tember.—The firft appearance of the Fever was* 1 about the 1 oth of Auguft; it increafed in violence 1 and in extenfion during all that month ; it was per** J ceived then to abate, and continued to do fo till the laft day of September, when a few frofty nights fu- pervening, it difappcarcd almoft iuddenly and en*- tirelv. ACCOUNT OF THE FEVER IN NORFOLK. I49 There were perhaps more deaths, than for many years before ; but whether greater in number to the proportion of the fick, than is ufual from autumnal difeafes, which prove as univerfal as that in queftion, we cannot undertake to determine. The fame mode of treatment generally fucceeded—as in other fea- fons. Our method was plentiful depletion in the be- ginning, not by bleeding, but by purging with Jalap, Calomel, Scammony, Aloes, or by the milder purges, the Neutral Salts—Sennse, Rhubarb, Manna, &c. as the age, fex and conftitution of the patient pointed out,—taking care that the evacuation of the firft paffages was complete, by whatever means procured* As foon as we judged that to be fufficient—which we always endeavored to make fo with as little delay as poffible—the bark was adminiftered in all and every form that it could be made to remain, without re- gard to quantity, or to the period, or height of the fever, with wine, porter, and even brandy, if wine was rejected by the inclination, habit, or ftomach of the patient. We can affure you, we have no reafon to alter our mode of practice in future. In a multitude of inftances, fome will occur in all difeafes, when a change, and fometimes a material change of reme- dies may be neceffary—fuch cafes we found, and in thofe we ufed Blifters, Emetics, Camphor, Opium. and often ventured upon Cupping—but never upon Vensefection.—This laft, a long courfe of practice has taught us to be at leaft, not advantageous. In diffe- rent climates, and under other circumftances—when the difeafe may have appeared in other grades than. thofe we have experienced—that operation is perhaps found ufeful. We wifh not to impofe our opinion, as a rule for any perfon ; fenfible of the fallability of all human judgment. We ever thought it our duty to give up our own theories, when contradicted by events. We only mean to r^conim^nd that y-hu, 15© ACCOUNT OF THE FEVER IN NORFOLK. j which long experience has taught us to be moft fuc- cefsful, There is no proof that this difeafe poffefled , any fpecific infection. It was rarely fatal to the na- tive inhabitants or the old fettlers, fpeaking of the , town only; but we have been told that many of the > traders from the Rivers and diftant part of the State, died immediately after leaving the port. The terror ; which pervaded all parts of the country, and deprived i thofe victims of the common attentions of humanity, j will eafily account for this without applying to the 1 malignancy of the difeafe. All, or moft of thofe born I in, or who had been accuftomed to a fouthern cli- ■ mate, efcaped death, and when attacked, had the dif- 1 eafe in its milder form. A large number of the inhabitants enjoyed unin,- I terrupted health ; moft of the deaths happened in j confined ftreets and buildings, and in thofe neareft 1 the river.—Thofe who were accuftomed to live well, 1 (as it is termed) did not fuffer fo much as the poorer clafs—But the intemperate of every defcription be- J came vi&ims when attacked-—The fmall pox imme- j diately preceded this fever. We did not obferve | that thofe who had been the fubjects of it were par- { ticularly fufferers.—There had been no malignant , complaint in the preceding winter. A particular defcription of the fever, and its fymp- ; toms, does not feem to be here neceffary, became, it. differed from the ordinary Bilious P.emittent, only in_ the rapidity with which it paffed through the feyer.irf'' i ft ages, and in its malignancy.—-This laft circumftance we are of opinion was occafioned by the long eorn> 1 Xiued and uniyer&l heat and moifture of the atrapfr ' phere.—The air was evidently impregnated with pu^ trid ef^uvia, arifing from .decayed fubftances of every fort, brought,sJo>yn upon the creeks and riyers by the ACCOUNT OF THE FEVER IN NORFOLK. 15! floods of rain, and thence into the bafon immediately before the town, where the ftream being wider, is lefs rapid than either above or below, and where of courfe fuch decayed fubftances, together with the filth, &c. thrown from the fhipping and docks, be- 1 came for a certain time flationary.—This may in fome meafure account for the difeafe appearing firft in the harbour.—The fame fever, with all its malig- nant anc\ uncontroulable fymptoms, occurs every • year in fcattered inftances, and about the feafon.—In the preceding fummer 'and autumn, feveral died with it. A number of fhips and veffels, which occafionally put into this port from James's River, and from North-Carolina, loft many of their people with a fe- ver of this fort, which they brought with them from the frefh and brakifh waters. In the prefent year : (1795) on board a fhip from Liverpool, which did not approach nearer than five miles to the town, and [ with the crew of which the captain affured us—No communication had been from the fhore, except by [ the health boat, almoft every individual was attacked with the difeafe, in ten days after her arrival, and one of them (a European) died, and this at a period when the difeafe had almoft difappeared in the town. We have before obferved that the exhalations from the • river, and the putrid fubftances carried down its i ftream, might have fome agency in producing or ag- ' gravating the Fever. The French fhips to which j you allude*, arrived fo long before the difeafe appear- ed, that it would be abfurd to fuppofe even a pofIL * X * The French corvettes, part of the fquadron, three of which i were taken by the Thetis, Captain Cochran, arrived and anchored in Hampton Roads, May 18. The Fever did not appear in Norfolk till Auguft. Capt. Cochran's crew, however, took the Fever from the French prifoners, and twelve of them died before {i.t Thetis arrived at Hallifax.----Editor. 152 ACCOUNT OF THE FEVER IN NORFOLK. bility of its being derived from them. We are of opinion, that there is not the moft diftant reafon to believe the Fever was imported at all. How far in towns like ours, the cuftomary diet ; and general mode of living, may operate in produc- ing putrid difeafes, remains for future obfervation to determine. It has been noticed by feveral medical writers, that frefh meats, and particularly beef in fouthern '■ climates, apparently generate fluxes and other ma- ; lignant difeafes ;—upon the latter kind of food, and \ on frefh fifh (both of' them frequently not of the beft quality) the poorer clafs of inhabitants fubfift during the fummers. Thofe whofe circumftances permit them to purchafe the beft kind of meats and fifh, cer- , tainly experience no inconvenience from thefe kinds of food. It has gone forth that the town of Norfolk is un- ; healthy and fubject to malignant difeafes in a greater degree than others. We may venture to affert and J truft can prove, that there are as few deaths in Nor- folk in the average of three years, as in any town of m the fame fize—not only in America, but in any part 1 of Europe, Afia or Africa, and with regard to its .1 natural population, a view of the ftreets will prove m that there are as many children raifed in it, as in anyM town whatfoever. It fhould be remembered that the II place has arifen from its afhes, in the courfe of a few years—that moft of the new fettlers have been Eu- ropeans, a people from northern climes. That there are always a thoufand or more failors, and ftrangers who are fubject to the difeafes of new comers—that almoft all who die, are carried for interment through the principal ftreet. . Hence, thofe who are unac- ACCOUNT OF THE FEVER IN NORFOLK. 153 quainted with the town, may naturally fuppofe, that deaths are more frequent, becaufe nearly ail that hap- pen, are actually brought into the view of every paf- fenger. Thus far we have attempted to lay before you as well as our leifure will permit, the beft information in our power. We have not prefumed'to enlarge up- on fpeculative opinions, but if our endeavours fhall meet the approbation of thofe who may perufe thefe meets, and you fhall think our correfpondence wor- thy of further folicitation; we will be ready to com- municate whatever we know, or may hereafter learn, on a fubject fo interefting to the American commu- nity. 2fcmlor 8f J%!anER IN NORFOLK. 155 buildings flood upon large log frames, filled in with fmaller wood of pine (chiefly the whole) that foon decays; this made Terra Firma by mud—Salt mud— Many of thofe large log pens, over which ftand tene- ments, now even are not filled in, but actually ferve as a receptacle for the offals of large and poor fami- lies, fo great a majority, as nearly to conftitute the whole inhabitants of that part of the town. Being t foreigners, they dealt lavifhly in beef, fifh, and all (, kinds of frefh food—obferve, this beef was driven ] perhaps from one to two hundred miles.before killed, E then expofed in a hot market to vend ; that by one o'clock, their dining hour, I always did, and do be- ' lieve, it muft have been tainted—Obferve, the fifh all dead by break of day, and brought by land from twenty down to twelve miles—hard drinkers of fpi- rits, moftly. The firft perfon who died, was Dr. \ Williams, a fat man, with very lax fibres, a very free liver, a grog drinker : he was taken with the ufual ; fymptoms of what an old writer upon the difeafes of I the Weft-Indies, calls a Bilious Remittent; he vo- • mited vaft quantities of bile; evacuated freely, as I appeared to me below, but had always a prodigious 4, fenfe of weight in the region of his ftomach. Belched I wonderful quantities of wind ; this relieved him for a m time. The moft fuffufion of bile in his eyes, nay all \ over the body I ever faw, which increafed as he vo- mited, and continued until petechias came on, with ...., a vomiting of black offenfive matter, which continued 24 hours, when a fit or two terminated his career.— |£: -How he was treated, I never inquired, though he was !; my friend. One or two more natural born citizens, were the whole, out of upwards of two hundred and ]• twenty, who in the fpace of fix weeks, fell a victim to this difeafe. The fymptoms were the fame in all5j except an obftinate coflivenefs—The natives live chiefly on falted meats and fowls, or other kinds of 1^6 ACCOUNT OF THE FEVER IN NORFOLK. poultry, which are killed but a little time before dreiT- ing, and the better fort have the greateft variety of j vegetables, are in more airy fituations, and not j crouded together; and upon my word, far more J healthy this year than I have feen them before. We .>, need not extend our views acrofs the Atlantic for < fources of difeafes; there are too many among our- , felves as you remark, and whether the principle' takes Culkn's, RuHTs, or your own name, putrid animal vegetable matter, united or mixed in water, by the heat of the fun, produces fomething noxious. to life. ! The object then deferves the attention of the po- lice, and when medical aid is needed, my plan is to allay the irritability of the ftomach ; to exhibit injec- tions ; to increafe the action of the alimentary canal downwards, which gives me an opportunity of throwing in a cathartic to evacuate the whole tract; J this I fometimes repeat, if the diftenfion of the fto- mach returns. Often when the vomiting inclined me to believe there would be a difficulty in my intention of evacuating as above; I have ufed with fuccefs, co- pious draughts of hike warm water, fometimes grog— the patient puked eafier, and generally more bile,.; and the fpirits acted as a moderate ftimulus. An in- , fuiion of Serpent. Rad. in every ftage of the difeafe after the foregoing practice, which appeared to claim ^ a preference to the cortix peruv. it often bringing™ on a return of the naufea and puking, two of the moffcjH dangerous fymptoms. The Bark, Columbo and Ma- ■ deira wine, whenever it could be received with quiet- ,i| ude to the fymptom, were our fheet anchors.—'By this mode 1 have fuccceded well. SUMMARY VIEW OF DR. MITCHILL S OPINION CONCERNING THE CAUSES OF EPIDEMIC DISTEMPERS. JTlE begins by examining the conitituent parts of the atmofphere, and agrees with the modem phi- lofophers, that it confifls of a little more than a fourth part of oxigene gas or refpirable air, and fomewhat lefs than three-fourths of mephitic air or azotic gas. Thefe exift together in the form of a mechanical mix- ture, but not in a ftate of chemical combination ; and thus the volume of atmofpherical air, whofe two forts of particles, move freely to and among esch other, in common circumftances, contributes to thefupportof fire and animation. But though the ingredients of the atmofphere exiit in a diftinct and feparate form in ordinary cafes, yet this is not univerfally the fact. Oxi^er.s, the bafis of vital air, and azote, the bafe of foul air, though fre- quently disjoined, do however poffefs attractive pow- ers, ftrong enough to make them oftentimes com- bine. The chief impediment to their union, is the clofer affinity which they, in their gafeous or aerial forms, poffefs for the caloric or matter o* heat con- nected with them, and from which they derive their properties as elaltic fluids. Whenever, therefore, oxigenp and azote can come together without aflum- ing the intervening form of gas or air, then they wail unite according to the law of chemical affinities, and conftitute by their junction, a body or compound, I58 DR. MITCHILL, ON CONTAGION. pofTeffing qualities very different from either of the conitituent elements. It is known from experiment, that both thefe ele- ments enter into the compofition of animal and vege- table fubftances. When oxigene unites with mere caloric, as in Fontana's experiments on infects, and Ingenhoufe's trials upon plants, then vital air will be the miafma proceeding therefrom. When azote ef- capes in connection with caloric only, as in Mr. Mitchill's own experiments,upon the lean and mufcu- lar parts of animals, and upon the air collected in the tumid bellies of animals, drowned or ftrangled, the effluvium is atmofpherical mephitis. When the two fubftances enter into combination with each other directly and immediately, without firft taking upon themfelves the aerial form, as in Maffey's experiments, the product is an acid, which, on addition of pot-afh to it, forms nitre or falt-petre. Here, then, during the decompofition or putrefac- tion of organifed bodies, as in Thouvenel's experi- ments, in a range of heat equal to that which the fur- face of the earth acquires on the American continent, in the fummer time, is an acid compound, formed by chemical agency, from the fame materials which con- ftitute in their feparate ftate, atmofpherical air; and capable as in Lavoifier's experiment, of being refolv- ed into it by analyfis. This acid, which is thus af- forded during the decay or refolution of organic matter, confifts of the like ingredients as the air we' live in, and differs from it but in two refpedts, to wit, the chemical connection of the materials and their different proportion. And the analogy between the. atmofphere, plants and animals, and the acid of falt- petre, as to their formation arid conftitution, muft be thus very apparent. DR. MITCHILL, ON CONTAGION. 159 Thefe points being determined, profeffor Mitchill crilicifes the preceding chymifts for their miftake in claffing this acid among the mineral fubftances, con- tends upon the authority of their own conceffions, that it is generally the refult of animal putrefaction ; and profeffes a reform of the French Nomenclature, that the language of fcience may truly correfpond to facts. He accordingly derives the name of the radi- cal term, from the Greek word, fepo, to putrefy, and calls the azote of the French academicians fepton, the putrid principle or principle of putrefadion. He calls azotic air by the name of feptous gas, dephlogiflicated nitrous air, gafeous oxyd of fepton, nitrous air,fepticgas, nitrous acid, feptous acid, nitric acid,feptic acid, &c. &c. and thereby, in the very phrafeology, the origin and formation of the productions, are invariably fuggeft- ed to the mind. Having in this way reformed the language of Chymiftry, the profeffor goes on to inquire, what is the evidence of nitrous or feptous acid exifting in the atmofphere, or in any of its modifications, af- fuming a volatile or aerial form. That there is fome- thing unwholefome and noxious in the exhalation from corrupting bodies, both of the vegetable and animal kind, has been long miferably experienced, though the precife nature of this has fcarcely been imagined, but has rather been confidered as lying beyond the reach of human refearch. He finds with Margraaf that this very acid exifts in rain water, and concludes with Watfon, that fnow-water is not free from a tincture of it. He agrees with Chalmers in afcribing to its operation, the fpeedy rufting of me- tals in hot latitudes, where the prefence of an acid is Y ~b£> LiR. MirCHILL, j manifeft in the atmofphere. But he docs not flop ] here ; for on confidering that the plaifter and wall of old buildings, has become impregnated with the fep- 1 tous or nitrous acid in the courfe of time, efpecially I if the inhabitants have lived in an unclean manner, "i and the houfes have flood in the neighborhood of foul J and corrupt vapours, he thinks the conclufion unde- I niable that this acid muft have exifted in a gafeous or 1 vaporific form, before it was attracted by the clay or i lime of the mortar. While in countries where falt- petre is found fpontaneoufly formed and ftrewed over the furface of the ground, the unhealthinefs of fuch regions is to be afcribed to the agency of that very gas, which united in a more concentrated ftate with potafli, conftitutes afterwards the nitre of the foil.—— The tarnifhing of metallic fubftances, highly colored iilks, the human fkin and countenance, he confiders as caufed in a great degree by the operation of the fame deleterious fluid, extricated from putrefying bo- dies. i Such a gafeous exhalation being now proved to exill, the profeflor endeavors to fliow that epidemic . difeafes muft be occafioned by it, and not by any other known fpecies of aerial fluid. This mifchiev- i ous matter cannot be carbonic acid or fixed air, be- caufeits effects upon animal bodies are entirely of a \ different kind, from thofe manifefted by infectious , ailments. Nor can it be inflammable air or hydrogene gas, whofe extreme levity foon elevates it high into the atmofphere, or whofe inflammability or odorous nature would directly make its prefence evident to the ] fenfes. Still lefs can it be alkaline air or ammoniacal gas, which though commonly efteemed one of the refults of putrefaction, is feldom or ever afforded but by force of artificial fire, and if it was fpontaneoufly evolved in low temperatures, would inftantly lofc it? ON CONTAGION. l6"l properties by combination with fixed air, or exhibit them to the noftrils by mingling with water. And nobody has ever imagined it was azotic or feptous gas. It being thus negatively eftablifhed, that contagious air can be neither of the fluids now enumerated, Mr. M. inquires whether that very curious and wonderful modification of feptous acid, called by Priestly, dcpblogiflicated nitrous air, and by Troostwyck and Deimann, the gafeous oxyd of azote is not in moft cafes the very caufes of endemic maladies ? This opi- nion he adopts, with this latitude and extent however, that the feptous acid, as well in any other volatile form, as in that of the oxyd, may be, and is productive of extenfive and dreadful ficknefs. It is very abun- dantly produced in the operations of nature, and may not only be confidered as evaporating from putrefying fubftances, but as formed in the atmofphere, by the inftrumentality of lightning, after the manner of its production by electrical explofions in Cavendifhh ex- periment. The reafons why this plentiful production has ge- nerally been hitherto overlooked, are, ift. That as it has ever been confidered a mineral fubftance, becaufe of its being ufually procured by the decom- pofition of nitre, no one has thought of inveftigating its hiftory, as an animal production: and 2ndly. Though it is fatal to breathing animals, yet it poi- feffes at the fame time a power to fupport combuf- tion, and has few obvioufly fenfible qualities, fo that perfons who have lived half their lives in an air more or lefs infected with it, never once imagined the ex- iflence of fuch a thing. To thefe products of putrefaction, all of which Mr. M. has made the fubjects of public experiments, are i6z DR. MlTCHILL, the phenomena afcribed to human and marfh miaf- mata, to be referred. The copious extrication of fuch gafes, their local origin, their limited diffufion, j their deleterious effects, all point to fome modification , of the nitrous acid as their caufe. And upon the j prevalence and action of this kind of fluid in the at- J mofphere, does he account for the frequency and univerfality of endemic and epidemic diforders; re- j jeering altogether the pretended diftinction between. | contagion and miafma, concluding with Gardiner, Bingle and Carburi, that they are but varieties of the J fame thing, and differ from each other but in de- j gree. The exhalation from graves mentioned by Faur* crni, and from diffecting rooms defcribed by St. jfohn, as well as the Harmattan breezes of Guinea noticed by Lind, and the Simaom blafts of Arabia, witneffed by Bruce ; he thinks are, in all probability, modifications of a fimilar aerial production. And this may ferve to give an idea of the extent and fcope of his reafon- ing on the occafional production of a gas, which while it continues to furround and inveft the inhabit- ants of particular fpots or countries; often deftroys J their lives, or at leaft impairs their health. The ef- I feet of this being manifefted upon the fkin and 1 lungs only, appears in the form of intermitting and 1 remitting -its, and in thofe peculiar cafes of anxious ■ and iuill.eating fever, cf which fome extreme and | exquuite relations have been made by Lind, Chifholm and jackfon. The fame reafoning by which Mr. M. became convinced of the exiftence and agency of thofe vari- \ ous compounds of the feptous principles, in cities, fwamps, and ir.nrfhes^ led him to examine whether ON CONTAGION. 163 they were not fometimes produced within the Hu- man flomach. The worft diftempers we hear of in ! hot climates, occur lefs among the Natives, than I among the Europeans, who for the purpofes of com- V nierce or warfare, vifit the torrid zone. They adapt > their drefs to the climate, but rarely make any alter- ? ation in their grofs aiid northern diet. In hot coun- tries, the digeftive powers are very apt to fail. The \ aliment, particularly among the Anglo-Americans and Englifh, who love to eat their meat half raw, \ foon runs into a putrefactive mafs, and the corrofive acid formed in the fceptic p'rocefs, excites that fad and fhocking train of fymptoms, which conftitute and characterize the Yellow-Fever. This malady, the very name of which ftrikes the citizens of the United States with terror, is fo particularly inherent in the ftomach and bowels, that Richter,Wade, and other well-informed practifers, have boldly termed diftem- pers of this type, Inteflbial, or Gqflric, or Dyfenieric Fevers. That the food of moft perfons who fuffer by thefe 1 complaints is in a confiderable proportion, animal, and putrifies in the ftomach and interlines, no body has ever doubted. In a range of heat, not much greater than occurs in the fubjacent earth, or fur- rounding air, the products of putrefaction muft be nearly the fame, in the ftomach, as cut of it; and the feptous principle, in fome or other of its modifi- I cations, be the refult. The greennefs of the bilious difcharges, is evidence enough in many cafes of the exiftence of an acid in the alimentary canal; and was there not too much of it produced to be neutralized by that alkaline liquor, the bile, far lefs mifchief would be done by it. And while fefli-eaters are mi- ferably afflicted, he obferves that the Arabians, Gen- toos, Chinefe and Negroes, who, though inhabitants 164 DR. MITCHILL, of fultry climates, fubfift chiefly on vegetable fare, are very little affected by this kind of ficknefs—Moft ve- getable fubftances being either lefs prone to corrupt, or if they putrefy, affording little or none of that pe- j culiar azotic produd which renders animal rottennefs- fo foul and deftructive. Thus, upon the idea of fceptic acids and vapours, vitiating the pulmonic functions, and thereby imped- ing breathing, or interrupting the digeltive procefs, and eroding and inflaming the ftomach and inteftines, Mr. Mitchill, thinks the phenomena of moft febrile ailments, whether of the endemic, epidemic, or dyfen- teric ; contagious, infectious or gaftric, intermittent, remittent or continued forms, may fully and fairly be explained. Having by this mode of experimental inquiry af- certained the proximate caufe of fever, the profeffor 1 proceeds to give a theory of it; and after the manner of Cullen, takes a fingle paroxyfm of an intermittent as an inftance. Judging from its effects, he confiders contagious air as always in fome degree ftimulant •, though from its non-refpirable property, operating 3 upon the lungs in breathing, in fuch a way as by fub- 1 ducting heat and cxygene from the body, to diminifh 1 action and energy, and thus induces a ftate of dired ■ debility. This debilitating procefs may be carried ■ fuddenly to a fatal extreme, as when the concentrated M peftilential air, inhaled, kills upon the fpot; or when 1 in a lefs noxious f irm, it may not extinguifh life im- I mediately, but caufe an anomalous difeafe of three ] days continuance, without remiffion, or in which J there are five or fix hot and cold fits, in twenty-four hours, eventually terminating in death. In a form yet more dilute and mild, epidemic air may occafion common remittent and intermittent diftempers. ON CONTAGION. 165 ' The cold ftage of fever, Mr. Mitchill confiders as depending upon impeded refpiration, and the impeded refpiration as depending upon the vitiated quality cf the air taken into the lungs; or in fome flighter cafes, where the flomach is originally thrown into a difordered condition, the lungs by affociation with that organ, are thrown into a diforder too, and for a time perform their functions imperfectly. Thus he prefumes it is, that the impeded ftate of refpiration, is attended with a fmaller evolution of heat and oxygene in the lungs, and confequently with more or lefs diminution of the circulation of the blood, and a proportional degree of chillinefs or cold- nefs throughout the body. The duration and degree of the cold fit will correfpond to the continuance and power of the caufes difturbing the pulmonic organs, either by acting upon them diredly or indiredly through the medium of the ftomach. From the fmall quantity of heat and oxigene, com- municated to the blood in the lungs, and its confe- quent flow and feeble circulation, can the fhrinking, palenefs, tremors, coldnefs, debility and other fymp- toms, be fufficiently explained, as the conftitution is now deprived of its two chief flimulants. But, why, it may be afked, does not the continued operation of the vitiated air upon the lungs, or the affociated con- (dition of the lungs with the ftomach, go on in an in- creafing feries even unto death ? It is a fact that fun- dry poifonous fubftances grow by degrees habitual to *:. the human conftitution, and by cuflom lofe theirpri- • mary operation. This difpofition to become familia- rized to contagious air, is particularly evident, as re- fpects the inhabitants of Guinea and the Weft-Indies. The conflitutions of thefe people are fo feafoned to the air and clinuite they live in, that in ordinary l6j DR. MITCHILL, cafes, it excites in them no difturbance at all. Now, common paroxyfms of intermitting fever, are in- ftances of temporary feafonings, which the conftitution experiences, of a kind quite analogous to what is perpetual with the Africans and Creoles. The cold fit does fometimes terminate in death; and this happens when the conftitution cannot ac^' quire the habit of enduring the noxious caufe with impunity. In the generality of cafes, however, the infectious gas lofes its power of operation, before the conftitution is debilitated to death, and as foon as it becomes for this time fo much accuftomed to the con- tagious fluid; as no longer to be difturbed by its pre- fence,the cold fit ends. The length and violence of the cold fit will thus be, other circumftances being equal, in a compound ratio, of the impediment given to the refpiration by the infectious gas, and the facility wherewith the conftitution accommodates itfelf to its action. If three perfons then inhabit one houfe, it is poffible that one of them may become fo quickly ac- cuftomed to the air, as to have no diftemper ; a fecond may have a moderate difeafe of a few fits; while the third, pcffeffed of a conftitution not eafily moulded to a new habit, may be incommoded by a violent and obftinate difeafe. In every paroxyfm of an intermittent, the infection thus wears itfelf out; but this is only a temporary recon- cilement of the body to its action. When after a re- petition of fits, the diforder becomes milder and milder, and after a while wholly ceafes, this is a cafe of lafrinv reconcilement. And in this way, may a large proportion of fmall intermittents cure themfelves, while the credit of it is given to the bark! This pow- er of balm daily does wonders, and labors more effect ON CONTAGION. 167 tually for the good of the fick than bark, opium and antimony put together. 1 The attack of contagion being thus for a time over- \ come, refpiration grows free, full and frequent; the ■ lungs ceafe to be molefted by it; more vital air is decompounded there, and more flimulus is applied I to the heart and arteries, by means of the increafed . heat and oxygene now in the blood. The flimuli ope- rate more powerfully on account of the accumulated excitability of the body ; and a degree of excitement is thence produced, which fometimes ends in death, fometimes caufes delirium, and in almoft. every cafe exceeds the healthy range of heat. Perfons there- . fore who die in the hot fit, die of the indired debility induced by the increafed heat and oxygene, acting upon the increafedfufceptibility of the fyftem. The duration and violence of the hot ftage will be, other things being alike, in a compound ratio of the excitability accumulated in the cold ftage, and the heat and oxygene evolved in the hot one. When the ex- citability is exhaufted by the operation of the flimuli, the violence of action will ceafe, and the body grow cool. The fweating ftage follows of courfe, as in other i-cafes of the fubfidence of violent action. For after the exhaufted excitability of the'conftitution allows i exceffive action to go on no longer, the refpiration grows more moderate and eafy, the heart beats with S lefs frequency and force, and the arterial contractions f.are more regular and health-like ; and as thefe alte- ' rations go on, the hydrogene and oxygene of the • blood, now run together in the extreme veffels of the ' fkin, and forms the moifture which bedews, the fur- Z ioci DR. MlTClllLi., si face, and this afterwards flying off by evaporation cools by degrees the whole body down to its ordinary temperature. And as the arterial extremities of the reft of the body, affume their ordinary condition by the fubfidence of excitement, the other fccretions which had generally been fufpended during the fit, now return as before. After this, the conftitution, fo far accuflomed to the contagious poifon, regains its former vigour and fundions, as far as the exercife endured^ and the functions injured during the feveral fiacres, will allow. His doctrine of fever in fhort, is concifely this :__ The contagious fluid, by interfering with pulmonic action, brings on the cold flage, and would continue the fame until its termination in death, did not the conftitution in the mean time, acquire fuch a habit as to gain a temporary infenfibility to its action. This habit being induced, the cold ftage abates by reafon of the ftate of dired debility into which the body had been brought; refpiration becomes conse- quently quicker ; heat and oxygene are let loofe in the lungs, and becoming incorporated with the blood now warm, itimulate every part with more than ufual power, and occafion the phenomena of the hot flage, which terminates as foon as the accumulated excitability of the fyftem is fufficiently exhaufted.— The fweating ftage next enfues, which after what has been faid, hardly requires any further explanation. The interval between one fit and the fucceeding: one, will be proportionate to theflrength and duration'. of the habit acquired, Some perfons thus experience but one fit, and the difeafe vaniflies; for under the fame circumftances, they are never invaded by a fe-'\ cond. Others fuffer two fits, or a fucceffion of fits, and ij after a while become fo accuflomed to the ftimulus, ON CONTAGION. 160 that if always applied in the fame degree offirength; its effect is no longer felt upon the body. In other inftances again, fo hard is it for the conftitution to be moulded to a fettled habit of oppofition, that after en- during a great number of invafions, it becomes fo enervated and worn down, as at length to die exhaufted. The fpecies of fevers whether quotidian, tertian, quartan, or of whatever type, will be determined by the readinefs or tardinefs wherewith the contagion gains a new afcendancy over the body, or breaks the habit. And to this mobility of the animal frame, or eafe with which the habit is broken, is to be afcrib- ed, as well the frequency of the returns, as the length and feverity of the paraxyoms. The anomalous cafes of .fevers, which have puzzled Phyficians to explain and nofologifts to arrange, are as Mr. M. thinks, thus very natur .lly accounted for ; fince according to the variation of the caufe (fince the contagious atmofphere may be more or lefs denfe or concentrated, and may be more or lefs charged with carbonic acid, hydrogene gas, and other non-refpir- able airs) will be the variety in the effect produced; and as there may be infinite gradations in the noxious caufe, fo there may be endlefs variations in the morbid effect, which it would be impoffible to defcribe in words, and ufelefs if it could be accomplifhed. Hence he explains why a fucceffion of fits long conti- ?iued, may difpofe the conftitution to a repetition of fits, even when the morbid caufe is away. For though there may be a habit produced of infenfibiiity to contagion, yet a habit may in the mean time be eftablifhed in the bodily motions, of falling periodi- cally into trains cf adion, ever, when the original 170 DR. MITCHILL, ON CO! caufe is withheld or removed. Her jn there will be produced a habit of having pan yfms after the manner of temporary feafonings, while at the fame time there may be a habit formed of refilling contagion altogether, or of.obtaining a permanent feafoning as to J that. 1 And to this principle of the animal frame, he thinks I. may be referred all the febrile ailments from the 1 moft trifling intermittent to the more ferious remit- I tent, and to the folemn forms of continued fevers ; without calling in the aid, even mentioning the | names of fpafm, vis medicatrix, or readion of the fyf- tem : always wifhing to be underftood as compre- hending within the prefent theory, the animal move- ments referable to the before-mentioned caufes folely, and not extending it to embrace common catarrh, quinfy, pleurify, peripneumony, rhumatifm and other difeafes of the pyrexious type, which Mr. Mit- chill fuppofes to proceed from another and a very different caufe. TWO LETTERS RELATIVE TO THE YELLOW FEVER, AS IT APPEARED IN NEW-HAVEN, IN THE STATE OF CONNECTICUT, IN THE YEAR 1794. I. Letter from Dr. Monfon, jun. to the Publiflier, on the Origin, Symptoms, Progrefs, and Difap- pearance of the Yellow Fever, in New-Haven— &c. &c. II. Letter from Dr. Monfon, fen. on the Treatment purfued, and moft fuccefsful, in the Cure of the Yellow Fever in New-Haven—Sec. &c. TWO LETTERS RELATIVE TO THE YELLOW FEVER, AS IT APPEARED IN NEW-HAVEN, IN THE STATE OF CONNECTICUT, IN THE YEAR 1794. LETTER FIRST. ,fj On the Origin, Symptoms, &c. of the Tellow Fever, in New-Haven. a. DR. MONSON, JUN. TO THE PUBLISHER. A SIR, IN giving a hiftory of the origin of the Yellow, or Peftilential Fever, as it appeared in this City, in the year 1794, it will be neceffary to premife fome account of thofe difeafes which prevailed here, imme- diately before; that the Public may be enabled to judge whether there is any analogy between them and the Fever in queftion. Sometime in 1792 and 1793, the Scarlet Fever, or Ulcerous Sore Throat, made its appearance in Litchfield, Water-town, and the towns in the vicinity of New-Haven; and raged with great mortality. In September and Odober 1793, many of the Inhabitants of this town were affected with a flight Influenza; flinging pains in their jaws and limbs, forenefs in the mufcles of the neck, with a light Fe- 174 LETTER FROM DR. MONSON, JUN. Ver.—In November and December following, feveral children were affected with the Ulcerous Sore Throat. The fymptoms were not alarming ; and in every in- ftance it terminated favorably.—In January 1794, the difeafe affumed a more malignant appearance. In February, March, April, May, June and July, it was highly putrid ; and many fell victims to its ma- lignity. On the 1 oth of June 1794, the Peftilential, or Yellow Fever, appeared here.—Doctor Hotchkifs vi- fited Ifaac Gorham's wife, on the Long-Wharf.—' She complained of a violent pain in her head, back and limbs ; her eyes were dull, and flightly inflamed 5 fhe had naufea at ftomach, was obftinately coflive, with a moderate degree of Fever. No marks of in- flammation were difcoverable, by inflection, in the throat.—The diftrefsful fymptoms, above-mentioned, continued till the fourteenth ; when her pain and diftrefs fuddenly fubfided j and (he was elated with the profpect of a fpeedy recovery. In the evening, flie vomited matter refembling coffee-grounds ; and died on the 15th.—The Phyfician, who attended her, was ignorant of her complaint till he faw what fhe vomited. He then declared her difeafe to be the Yellow Fever. On the 15th of June, I vifited Elias Gorham's daughter, a child of 8 years of age, in Chapel-ftreet, three quarters of a mile from Ifaac Gorham's houfe. She had been fick three days; her countenance was fiufhed with a deep red colour; her eyes were dull, and highly inflamed ; fhe had violent pain in her head, back, and limbs; naufea, and frequent vo- miting ; obftinate coftivenefs ; a quick, full, hard, throbbing pulfe ; her fkin was hot and dry ; and her tongue covered with a thick white fur. On the TO THE PUBLISHER. 175 16th, her pain and diftrefs fuddenly abated; in a few hours, fhe vomited up matter refembling coffee- t grounds; and died the next day.—I infpected her throat, during her illnefs, and could difcover no marks of inflammation. I was furprifed at the fingular appearance of the difeafe, and hearing of the death of Mrs. Gorham (Ifaac Gorham's wife) inquired of the mother if her daughter had been on the wharf. She informed me that the child had lived with her aunt (Ifaac Gor- ham's wife) nearly a week. The 23d of June, I vifited the child's mother. She complained of violent pain in her head, back, and limbs; naufea; frequent vomiting j obftinate cof- tivenefs ; with a confiderable degree of fever. Thef© fymptoms continued five or fix days; then gradu- ally abated ; and foon after fhe recovered her ufual health. On the 20th of June, Mr. Elijah Auftin died in New-York; and his clerk, Henry Hubbard, died in Derby. They complained within three or four hours of each other; and Mr. Hubbard vomited matter refembling coffee-grounds. The inhabitants of this town were alarmed at thefe fudden deaths, and requefted the Seled-Men to make diligent inquiry into the origin of this dif- ■ eafe. On examination, it appeared-—That, in the be- * ginning of June, Capt. Truman arrived from Mar- tinico, in a floop that was infected with the contagion f of the Yellow Fever: that this veffel lay at the wharf, !• within a few rods of Ifaac Gorham's houfe: that fhe Tf6 LETTER FROM DR. MONSON, JUN. had on board a chcfl of clothes, which had belonged to a mariner, who died of the Yellow Fever, in Mar- rinico ; and that his cheft was carried into Mr. Auf- itn's ftore, and opened in the prefence of Capt. Tru- man, Mr. Auftin, Henry Hubbard, and Polly Gor- ham ; the three laft mentioned of whom, died, in a fhort time after their expofure to the contents of the cheft.—Hence it is highly probable that Mrs, Gor- ham caught the difeafe from the infected floop, or clothing. Mr. Auftin's ftore (lands within three or four rods of Ifaac Gorham's houfe; and no perfon in town was known to have the Yellow Fever previ-. ous to Capt. Truman's arrival. June 26th, Ifaac Gotham loft an infant child with the Yellow Fever ; and foon after his fon and daugh- ter were affected with it:—the former died.-—Solo- mon Mudge died on the 30th; Jacob Thomfon's negro woman, on the ift of July ; Archibald M'Neil >. on the 9th ; Polly Brown on the 3d of Auguft ;. John Storer, jun. and John Hide, on the 8th : and widow \ Thomfon, on the 10th.—Jacob Itiomfon's negro woman, Solomon Mudge, Johr. Storer, jun. and John Hide, had vifited Mr. Gorham's houfe, a few days before their illnefs; Polly Brown and Mrs. Thorn- v, fon, nurfed in Mr. Gorham's family ; and Archibald M'Neil nurfed Solomon Mudge.—Elias Gill, died on J the 12th of Auguft ; and Samuel Grifwold's wife, on M the 7th: the former, vifited Mr. Gorham's houfe j 1 the latter nurfed in his family. There were a number of perforfs who caught the difeafe at Mr. Gorham's houfe, and recovered. Mrs. Thomfon, on the firft day of her illnefs, was iT'Oved half a mile from Mr. Gorham's, into George- :;r:-ec. Luther Fitch caught the difeafe from Mrs. TO THE PUBLISHER. '77 Thomfon, and communicated it to his fervant maid. Both recovered.—Mr. Fitch lives in College-ftreeJ, nearly three quarters of a mile diftant from Mr. Gor- ham's houfe.—I could trace the difeafe throughout the town. No-perfon had the Yellow Fever, unlefs in confequence of attending the fick, or of being ex- pofed by nurfes, infected- houfes, clothing, or furni- ture. I have inquired of feveral aged perfons in this town, relative to the Yellow Fever, whether they knew of its having ever been here, previous to June 1794, and there is but a fingle inftance ; the facts relating to which are thefe:—In the year 1743, a tranfient perfon, by the name of Nevins, who came from the Weft-Indies, lodged at the houfe of Nathaniel Brown, an inn-keeper, in this city. The man was taken very fick, in the night; and died Inertly afterwards ; and his body was very yellow, after death.—Mr. Brown's wife fickened in a fhort time, and died, of the fame complaint; which was, at that time, fuppofed to be the Yellow Fever. I am credibly informed that feveral perfons, at Milv- River, in Fairfield county, and alfo at New-London, died with the Yellow Fever, in Auguft and Septem- ber 1795.. It was propagated there by infected per- fons from New-York. Capt. John Smith died in this town, the 20th of Auguft 1795. He caught the difeafe in New-York, and communicated it to one of his negro fervants. t78 LETTER FROM DR. MONSO.M. • JN. The following is an account of t- number who died, with the Yellow Fever, in Ne .-Haven, in the different months of the year 1794. June.......6 July.....> • 3 Auguft......16 September.....26 October......12 November.....1 Total, 64 Of this number, forty-eight vomited matter re- fembling coffee-grounds, or port wine.—There were about a hundred and fixty perfons who had the Yellow Fever.—Three perfons recovered who vo- mitted matter like coffee-grounds; but none re- covered, that I remember, who vomited matter re- fembling port wine.—Some vomited a vifcid, tough mucus, fimilar to the white of an egg ; others, mat- ter like chocolate; which were as fatal as the black vomit. The Yellow-Fever was attended with fpecific con- tagion in every inftance, and proved equally mortal in every part of the town, in proportion to the number that were fick. No age, nor fex, were ex- empted from it's ravages. All defcriptions of peo- ple were alike fufceptible of receiving the conta-i gion. In the month of September, when the Yellow Fever ^ raged with the greateft violence, the inhabit- ants, in general, were almoft entirely free from every other complaint. It was remarked by the TO THE PUBLISHER. 179 citizens, that they never knew it fo healthy, at that feafon of the year—excepting the Yellow Fever. The following is an accurate regifter of the r;uia- ber who died of the Scarlet-Fever, or Ulcerous Sore Throat, in 1794. February . . March . . April . . May . . • 3 • 5 • 5 . 10 July . . Auguft September October • 7 • 3 2 . 2 June . . • • J5 — 38 14 33 Total, 52 It was computed that 750 perfons had the Scarlet Fever.—This difeafe appeared in almoft every family in town, indifcriminately; and was evidently, an Epidemical difeafe, which originated in the confti- tution of the air,—while the Yellow Fever was prci- pagated only by contagion. The fymptoms of the Yellow Fever, generr.ily, were as follow:—Languor ; laffitude ; rigors; a dull, heavy, inflamed eye, with a dilated pupil; the coun- tenance flufhed, with a deep red color ; violent pain, in the head, back, and limbs; naufea; frequent vo- miting of matter highly bilious ; bitter tafte in the mouth ; tongue covered with a thick, whitiffi or yel- low fur ; a very quick, full, hard, throbbing pulfe; fkin hot and dry ; thirft very inconfiderable ; obfti- l8o LETTER FROM DR. MONSON, JUN. nate coftivenefs—and when flools were procured, they were of a bottle-green color, or refembled tar, or molaffes :—Thefe were the general characteriftics 'J of the difeafe; when it appeared highly inflammato- ry.—In fome inftances, the pulfe was very flow-— J diminifhed in frequency below the healthy flandard—r- -J and very feeble ; there was great oppreffion about : the precordia ; faintnefs ; difpofition to coma; a filly *m look of the eye ; exquifite irritability of the ftomach ; conftant vomiting; faultering in the fpeech; the coun- j tenance of a tawny, or copper color ; tongue moift, without any fur, and of a bluilh or coal black ap- ' pearance.—In fome I obferved a tort, quick, fmall pulfe, and fometimes flow, which would rife on bleed- ing, and become quicker and fuller. Where the difeafe raged with great violence, and was highly malignant, the remiffions of Fever were ; fcarcely perceptible to the moft attentive obferver. ' The pulfe would continue hard and full, till within a few hours before death; when the pain, diftrefs, J and fever, would fuddenly abate, and the pulfe re- J turn to its healthy flandard. Soon after, the fick J were affected with a vomiting of matter, refembling J coffee-grounds, or port-wine ; or with a coldnefs of : the extremities, which gradually increafed, till death 1 clofed the fcene.. M When the difeafe terminated favorably, there was 1 a gradual remiffion of the fever, pain, diftrefs, nau~ J fea, and vomiting. 1 Some were affected, on the third or fourth day, with hemorrhage, from the nofe and gums ; and. .J| fometimes, thefe fymptoms would'occur at a later period. TO THE PUBLISHER. 181 Others were affected with petechias, carbuncles, and livid fpots, on the face and breaft, as large as a dollar. One patient had a number of livid blotches, as large as a damfon ; fome of which difcharged a dark-colored, bloody matter. This patient recovered, on the 27th day of the difeafe. A young woman had the black vomit, on the third day of her illnefs. On the fixth, fhe had a large ab- 1 fcefs form, on the fuperior part of the right thigh, near the head of the Os Femoris; and a large car- buncle, on her loins, of the bignefs of a common fized bread cake, and of a livid color. It fuppu- rated on the tenth day; the mortified parts floughed off, and denuded the fpine. On the fame day, fhe had a deep abfcefs form on the left thigh, nearly op- pofite to the one on her right. Thefe abfceffes pro- duced deep, finuous ulcers, which did not heal till [ the fourth month of her ficknefs. On the fifth month, fhe was able to walk, with the affiftance of crutches; and foon after regained her health. Capt. David Phipps's wife, on the ninth day of her illnefs, was affected with the hiccoughs, and died on the eighteenth. On the feventeenth, fhe expec- | torated matter of an orange green colour, and ex- [ tremely fetid.—I have mentioned this circumftance ;, as a rare occurrence ; very few being affected with hiccoughing, or fubfultus tendinum. f The Yellow Fever generally proved fatal on the 1 third, fourth, fifth, and fixth days. There were three J or four inftances of its terminating fatally in thirty- fix hours. If the patient furvived the feventh day, , .he almoft always recovered. At this.period the fever frequently appeared to make a complete crifis. On the eighth day, it affumed the type of a double re- 182 LiTTER FRX3M DR. MONSON, JUN. mittent: two diftinct renditions were evident in the courfe of twenty-four hours, accompanied by profufe and intolerably fetid fweats, and often with white and read miliary eruptions. This fever feldom made any | regular crifis. It often continued till the twenty third or twenty fourth day, and abated gradually.— In the courfe of the difeafe, they often vomited a large quantity of green bile,—refembling the ex- J preffed juice of red pepper leaves. This evacu- ation feemed to relieve the difagreeable naufea which moft of them were affected with.—The dif- charge of bile was commonly the effort of nature ; gentle emetics, feldom or never, procuring a dif- , charge of bile. I faw two inftances of reinfection. The effects of the contagion were, generally, obvi- ous on the third, fourth, or fifth day, after expofure. In one inftance they did not appear till the thir- teenth. i The bodies, of thofe who died of the Yellow Fe- ; ver, were either of a tawny, or copper color : Some j were of a deep yellow ; and one almoft of an orange J green. Three appeared as if they were fprinkled i with ink. 1 In refpect to the origin and nature of the difeafe < under confideration, I efteem it juftifiable to reafon i from facts alone. I am fully of opinion that the. Yellow Fever is feldom, or never, generated in this country, and that it is always imported from abroad. *j An objection to the idea of its being generated in this country is, that it was never known in the interior of this ftate, or of the United States; fo far as I can TO THE PUBLISHER. •83 learn. Had it ever appeared in Connecticut, before the year 1743* and June 1794, we fhould, undoubt- edly, have had fome record of the fact. There is no fuch record, and no perfon remembers to have heard of fuch a difeafe, but at thefe periods, prevailing in any part of the ftate. There are numbers of aged t perfons in New-Haven, who remember the Putrid Ulcerous Sore Throat, Small-pox, Meazles, Dyfen- tery, &c. raging here, with great mortality ; but have no recollection of any Yellow Fever. Hence we may ' rationally conclude that it never did appear, in this ftate, but in the years 1743, and 1794. It is evident, from facts before-mentioned, in this letter, that the Yellow Fever was propagated in no other way than by contagion ; and that this is a. fpe- cific contagion, and no more diverfified, in its opera- tion on the human fyftem, than that of the Small- pox and Meazles. If the citizens of large commercial cities were at- : tentive in tracing the origin of the Yellow Fever, on its firft appearing among them, they would often find that the difeafe was imported. In fome inftances it would be extremely difficult to difcover the origin.— But the mifchief lies in this—that the inhabitants of fuch cities, whenever a contagious difeafe makes its: ; appearance among th»em, endeavor to fupprefs all I rumor of it, from an apprehenfion of alarming the ■ country, and injuring their commerce : unwilling to J' believe that there is evil in the city, till the difeafe 5. fpreads in every direction. Then, indeed, when it | is too late, they are folicitous in the ufe of means to ( arreft its progrefs, As it extends itfelf flowly, at firft, B b 184 LETTER FROM DR. MONSON, SEN. feafonable exertion might both detect its fource, and prevent its iricreafe ; but when it is diftufed through a city, it fpreads with rapidity, and it is no longer pof- fible to difcover where it began.—But as, whenever! the Yellow Fever has appeared in the United States, it has always been in fea-port towns, and originated near wharves, docks, and warehoufes, there feems to be high probability that the difeafe is imported. With fincere efteem, I am yours, &c. ELIJAH MONSON. New-Haven, April 24, 1796. LETTER SECOND. I On the Treatment moft fuccefsful in the Cure of the Yclkzo Fever, in New-Haven, in 1794, &c. &c. DR. MONSON, SEN. TO THE PUBLISHER. DEAR SIR, The communication which accompanies ^ this, from my Son, contains an account, fufficiently minute, of the origin, fymptoms, fatality, &c. of the Yellow Fever, as it appeared in New-Haven, in 1794, together with his reafons for believing it to be a difeafe of foreign derivation, and of fpecific conta- gion.—I have referved to myfelf the talk of convey- ing to you fome information refpecting the plan of cure generally adopted ; on the juvantia and ceden- tia; and relative to fporadic cafes with fimilar fymp- toms. I TO THE PUBLISHER. l85 In June 1794, when the peftilential or Yellow Fever, made its firft appearance here, the Scarlatina Anginofa was rife, with great malignancy. It did not, at all, admit of the ufe of the lancet; but, on the contrary, we found the bark, mineral acids, and high flimulating cordials, moft fuccefsful in promot- ing the cure. This Fever exhibited confiderable va- riety of fymptoms, in different circumftances and habits. Sometimes, the forenefs of the throat pre- ceded the fcarlatinous efflorefcence ; at others, the cuticular eruption appeared previous to the difficulty of fwallowing and forenefs of the throat: and in others, again, there was no eruption on the fkin, from firft to laft, and only a temporary complaint in the throat, but a gangrenous affection of the Tenuis, which was foon communicated to the habit, and proved fuddenly fatal. The Scarlatina Anginofa be- ing thus the conftitutional Epidemic, and ufhered in with many of the fame fymptoms with the fuper- vening Peftilential Fever, it will not appear very ex- traordinary that, on its firft appearance, the one fhould be miftaken for the other. This was the cafe, in refpect to a number of thofe firft feized with the Yellow Fever ; who being treated with bark and cordials, without much previous evacuation, rarely recovered. Indeed, of feventeen, or eighteen, who were earlieft affected, fourteen died. But, whether this fliould be afcribed to the treatment, at this period, folely, or to the nature and virulence of the infection, I am not fatisfied. For I am confident that the Fever affumed a more malignant afpect in thofe who received the infection from the Fcmites of the difeafe (which was moftly the cafe at firft) than where it was derived immediately from the bodies pf the fick : which obfervation, if juft, confirms the opi- nion of Dr. Cullen, refpecting contagion. I 86 LETTER FROM DR. MONSON, SEN. This extraordinary mortality having convinced us of the impropriety of trufting to, or ufing, cordials, bark, &c. we, with one accord, had recourfe to the lancet; endeavoring, at the fame time, early to cleanfe the firft paffages with ftrong purges, compofed of Jalap, Calomel, and Aloes : for the fick were ob- ftinately coflive, in general, and required much phy- fic to move them, and frequent repetitions to keep the bowels open. Thefe evacuations were very evi- dently attended with the moft fpeedy relief of head- ach, naufea, and oppreffion ; the flools procured, by the purges, were commonly of a greenifh, or dark bi- lious tinge ; and, where the bile was brought off co- pioufly, it was not ufual to fee that yellowifh fuffufion of the eyes, and furface of the fkin, throughout the courfe of the difeafe, which was formerly accounted a principal diagnoftic, and has given name to the Fever. The repetition of the lancet was neceffary, to third or fourth day, in fome habits, as were the mercurial purges. There was little dependence to be placed on diapo- retics, by reafon of the extreme irritability of the ftomach. Baths and fomentations, in fome cafes, were highly palliative. The fermenting mixture, fometimes reftrained the vomiting. This effect was, likewife, produced by blifters, applied to the region of the ftomach. When applied juft above the knees, they appeared to be attended by decided advantage, in diminifliing the frequency of vomiting, relieving the head, palliating nervous affections, removing coma, and encouraging diaphorefis. TO THE PUBLISHER. 187 Clyfters, often thrown up into the bowels, were peculiarly ferviceable, not only to affifl in effecting the more eafy and thorough tranfit of the Phyfic,but to cool the bowels, attenuate the vifcid colluvies, and difpofe to perfpiration. The Bark, in the decline of the Fever, anfwered a good purpofe, where it could be retained; but there were but very few who could bear it in fubftance, and not many in any form. Opium, whether adminiftered to relieve pain, or flay the vomiting, was obferved to have the moft pernicious effects ; efpecially in the early ftage of the difeafe. A man and his wife, who had been accuf- tomed to the ufe of Laudanum, on former occafions, when feized with the diftrefling fymptoms of this Fever, had recourfe (in the beginning of their illnefs, and previous to any medical advice) to the liberal ufe of that medicine, for the relief of their pains ; and both died in about thirty fix-hours. A free, cool, well-ventilated apartment was of the greateft importance. The paffions of the mind had a very fenfible effect on the fick.—The paffion of fear, in particular, was not only highly predifpofing to the reception of the contagion, but a very fatal concomitant. Hence the [ pufillanimous and fearful, when expofed to the caufe of the difeafe, rarely efcaped ; and hence the fatal | confequences which, in fundry inftances, followed from funeral knells, which were, in general, mani- feftly detrimental. On the 6th of September, I was myfelf feized with the common fymptoms of the Fever. My ha- bit being liendcr, and as I had been worn down with I 88 LETTER FROM DR. MONSON, SEN. fatigue and much expofed to the night air, I was cau- tious of ufing the phyfic in the quantity I had been wont to give it to my patients ; at the fame time fearful I fliould not be able to retain it on my ftomach. I found, by the gradual introduction of it, I had, by the third day, confiderably affected my habit with the mercury. I no fooner perceived my gums and fauces touched, than I found that almoft intolerable oppreffion about the precordia yeilding and fubfid- ing.—Upon reflection, I recollected a circumftance which before I had not attended to—That, where the mercury, in the purging pills generally ufed, had fo far infinuated itfelf into the habit as to produce any forenefs of the mouth and gums, the patients had univerfally recovered. I mentioned this circumftance to my brethren of the faculty, who, on recollection, sffured me that their uniform experience confirmed the fact: none of them having loft a patient, where the mercury had produced ptyalifm. Thenceforward our main object, after cleanfing the firft paffages, was to introduce mercury into the fvftem, as fall as poffible, both by the ftomach "and by friction.—This appeared to be a more eligible and fuccefsful treatment, than to repeat the mercurial purges; through the courfe of the Fever. Notwithftanding the evident fymptoms of inflam- mation, in this Fever, I cannot fay but that, in fundry inftances, large and repeated bleedings appeared to fink the patient, and proved detrimental; and purg- ing, alfo, was fometimes, carried to excefs. Yet, in no inftance, v as bleeding pufhed to near that extre- ■irty, as was often practifed in Philadelphia.—I would ra t, however, be underltood, in any meafure, to c:nfure the practice of the faculty in Philadelphia ; £.'!• it is well known that difeafes of the fame name To THE PUBLISHER. 189 and type, at different times and places, require dif- ferent treatment. The Yellow Fever, too, when it prevailed among us, may be fuppofed to partake, in fome degree, of the nature of the conftitutional epi- demic then exifting;—I mean the Scarlatina Angi- nofa, in which nothing was more fatal than the lan- cet : for, whatever inflammatory fymptoms appeared in the beginning, there was almoft univerfally, a fud- den transition, from the inflammatory, to the putrid diathefis, which called for the early ufe of tonics, and highly ftimulating cordials. And the Yellow Fever, though ufhered in with ftrong inflammatory fymptoms, yet terminated, when fatal, with thofe of an oppofite nature. There were no diffections made in this town ; but, from all the fymptoms attending, I could , not have entertained a doubt of finding a morbid affection of the liver, had not gentlemen of the faculty, and emi- ?• uent in their profeffion, in Philadelphia, and in other places where this Fever has prevailed, decided to the contrary. But there has never been, I believe, any ; uniform appearance of this Vifcus difcovered on the [ diffection of thofe who have fallen a facrifice to this difeafe.—But if the liver be not primarily affected, ; may it not be a queftion whether the remarkable yel- lownefs, noted in the eye, and over the whole furface of the body, be any thing more than a confequence ;i of that coftive, torpid ftate of the inteftines, in the < v early ftage of the difeafe, which, by retaining the bile, now conftantly pouring into them in its ufual, or perhaps increafed quantity (as may be fuppofed [ from increafed excitement of Fever) allows an ab- f forption by the Cacteals to take place, and thus pro- ['•' duce this phenomenon—according to the fuggeftion of M. Portal ? 190 LETTER FROM DR. MONSON, SEN. Many circumftances feem to favor the idea that the liver is affected primarily : fuch is the pain, either , dull or acute, fo univerfally perceptible on preffure < with the hand on the region of that vifcus, and ! which increafes with the difeafe;—(and I have known j it to that degree, that half the weight of one's hand m would produce fwooning)—and fuch, alfo, is that 1 tenfity and diftention of the integuments.—Both Warren and Hillary fuppofed the liver to be the feat of the Fever ; and Dr. Broag, who performed many difiections in this Fever, and in the Dyfentery of hot climates, obferves that the liver was almoft always found difeafed. And Dr. Hunter remarks, that a difeafed ftate of the liver and fpleen has an intimate connection with the difeafes of hot climates. But whether the difeafe of the ftomach and intef- tines precede that of the liver, or the reverfe, they muft all be more or lefs affected, in the progrefs of the Fever. For it cannot be fuppofed that fo violent and long-continued a derangement of the alimentary canal, as is evident in the Yellow Fever, could take j place, without extending its diforder to the functions .. of the liver, if not to its very fubftance.—But per- U haps a decition on this point can make little altera-*' jj tion in the method of cure; a local inflammation in J any of the Vifcera being, doubtlefs, to be fubmitted-^ to the fame general plan of treatment. V There is nothing in the hiftories of the Yellow i Fever, which I have feen, more extraordinary than that gentlemen, clearly eminent in the profeffion, fhould fo decidedly give it as their opinion that the A difeafe is not infectious. Dr. Hunter remarks that, I in no inftance, did the Yellow Fever prove more in- 1 TO THE PUBLISHER. I9I fectious than the Remittent; and that it was to him matter of confolation to be able to declare it not to be an infectious difeafe. And Dr. Mofely, if I am ,, not miftaken, is of the like fentiment.—Now, with us, the contrary of this is demonftrated by the moft ob- I vious facts. In a climate where the difeafe is not epidemical, i and where it is not generated, we are under advan- tages to decide, with much more certainty, in refpect 1 to its infectious nature, than we fhould be in a hot climate ; where the long-continued heat, in conjunc- tion with a number of other caufes, is productive of the diforder, and where it would, therefore, be very difficult to determine when the Fever was conftitu- tional, and when propagated by contagion. We have never, in this part of the country (except I in a fingle inftance in the year 17435 mentioned in [ the preceding letter) been acquainted with a Fever ■ altogether fimilar to the one in queftion. True, I fome chronic complaints in the vifcera, as well as § acute fporadic fevers, ending in fphacelation, have i been attended with the vomiting of a fluid, putting I on the appearance of coffee-grounds, and terminated JL in a black vomit. We have often feen continual en- p demial fevers, intermittent, and remittent bilious fevers, originating from the putrid gafes of animals m and vegetables commixed,—as from draining of ■ ponds and ftagnant waters:—but no difeafe from thefe fources, or any in our climate, I conceive, ever V compared with what is generally known by the name : of the Yellow Fever—no difeafe attended with fo great rapidity, or characterized by that deep-fhaded, K univerfal yellownefs, and vomiting of black-colored 1 matter—oozing from the furface of the ftomach. C c 192 LETTER FROM DR. MONSON, SEN. Dr. Ferrier obferves, that peftilential diforders are not to be afcribed to animal putridity. Inftances have been adduced in which thoufands of dead bo- dies, have been left to putrify on fields of battle, without producing peftilential fever ; nor have fevers been obferved to originate, or to rage more feverely, ^ in houfes furrounding Church-yards; though the M ftench is often infufferably offenfive. And, fays the J fame author, it is a queftion whether the dead body of a perfon who perifhed with the plague or fever, be 1 capable of communicating infection.—I conclude, 1 then, that the contagion of the Yellow Fever is ifpe- I cific contagion ; and that, in this climate, it is propa- I gated by animal poifon, in a gafeous form, proceeding from a living human body difeafed—and in no other way—and fuppofe it to act immediately on the ner- vous fyftem. In hot climates, where the Yellow Fever is gene- , rated, there is a combination of caufes that do not exift here. There is, Dr. Blane tells us, fomenting peculiarly noxious in the land air.—The moft perni- J cious practice, to Europeans, when newly arrived in hot climates, is exercife in the heat of the fun. This, joined to intemperance, renders fuch climates fo fatal to foreigners.—Befides the obvious effects of bad air, M depending on heat and moifture ; the Dr. mentions W feveral inftances of the fingular quality of air in par- ■ ticular places—which, though its influence cannot be 1 accounted for, has yet certainly the effect of produc- M ing the difeafes peculiar to fuch places. TO THE PUBLISHER. J93 I regret that my leifure, from the avocations of bu- finefs, will not permit me to furnifh you with a more ample and better arranged ftatement of the facts and reafonings, in relation to the prefent fubject.—Next to our acquaintance with the Deity, and the terms of acceptance with him, the knowledge of the natu- ral evils to which human nature is fubjected, and the means of avoiding, and removing them, demand our higheft and molt ferious attention.—To this end, I highly approve of your defign ; and that profperity may attend you, in your laudable undertaking, for thefe purpofes, is the ardent wifh of Your Friend, and Humble Servant. ENEAS MONSON New-Haven, April, 1796. ■f LETTER, OF DR. REYNOLDS, TO THE PUBLISHER. SIR, 1 AM happy to hear that you purpofe collect- ing a hiftory of the Epidemic Bilious Fever that has of late made fuch ravage in feveral places in Ame- rica. By thus placing within fo fmall a compafs, the practical experience of thofe who have had an op- portunity of treating and being acquainted with that difeafe, much ufeful knowledge of the fubject may be diffeminated, and the general good of mankind pro- moted. To aid this undertaking, I fend you the following, j which if you think worthy of notice, will find a place in your collection. y For the fall and winter of the year 1792, and in the fummer following, an Epidemic Bilious Fever, appeared with much violence in the town of New- [ Galway. In general the firft attack was not fevere—for one \ or two of the firft days, the patient might rather be \ faid to be unwell, than fick.—But this ftate continued \ not long—foon a violent fever,- with fevere pains in various parts of the body, commenced—very fre- quently a naufea and vomiting, and fometimes a vio- lent purging, were early companions of this difeafe. In patients "of a delicate conftitution, the pulfe was ig6 LETTER FROM DR. REYNOLS, fmall and quick from the beginning; but in others of a more robuft habit, the pulfe was full and in fome cafes very regular, although the other fymp- toms were much aggravated.—They feldom com- ; plained of much thirft after four or five days, al- though the mouth and tongue were dry and foul.— * Moft of thofe cafes that proved fatal continued till after the twelfth day, and many till the twentieth $ from the onfet of the diforder. 3 I In fome few cafes at the beginning of the difeafe, bleeding appeared to give fome relief. But in moft of the inftances where I had an opportunity of ob- ferving its effect, it was evidently hurtful.—The fame I can teftify with refpect to frequent purging. My general mode of treating this difeafe, I pub- lifhed in the Albany Regifter (a copy of which I fend ] inclofed)—And I have fince frequently had the fatif- ; faction to hear from gentlemen of the faculty, that my mercurial method had proved remarkably bene- ficial within their experience.—'Tis not within my , power to trace the origin of this difeafe, in this place, to any known caufe. The country has been im- proved about ten years, and previous to this, and fince, has been remarkably healthy, except a fmall number of cafes of the Maligna Angina, which not ( only occurred in this, but in all the neighboring! towns, where nothing of the Bilious Fever followed.' It began late in the fummer, and continued till the the next fpring. It was expected that the winter would check its malignancy ; but on the contrary, 1 many of the worlt cafes happened in December. 1 In the fummer following, a very extraordinary cafe 1 happened. Upon the border of a marfliy piece of ■» land, ahorfedied, and was fuffered to remain above TO THE PUBLISHER. I97 ground and putrify. A young woman who lived near the place having frequent occafion to pafs near the carcafe, was feized with a violent pain in her head and ficknefs at the ftomach. On the fecond day from the attack, a phyfician was called, who let blood from the arm ; but her fever increafed, and fhe foon became delirious. On the third day when I firft faw her, every fymptom appeared fatal. Upon her feet and hands, fingers and toes, a number of blifters, fur- rounded by inflammation, appeared—and a real mor- tification had already begun upon the ends of fome of her toes—The blifters and places of mortification continued to increafe till the morning of the fourth day, when fhe died. The fatality attending this cafe, will fhew the ne- ceffity of burying all animals that may die in the fum- mer feafon near any habitation. A precaution little attended to in the country. STEPHEN REYNOLDS. Montgomery County, State of New-York, December 27th, l795- I98 LETTER FROM DR. REYNOLDS, v Thefollowing is the Paper mentioned in theforegpingLetter. FOR THE ALBANY REGISTER. The method recommended by Dr. Rufh of | treating the contagious Fever now fo prevalent in ■■ Philadelphia, is by fome phyficians objected to, be- 'M treating the Contagious Fever now fo prevalent in ^ caufe fo fimple ; by others, from an idea that mercury a can never be advantageoufly ufed in fevers, efpecially I in thofe of a putrid kind. Fully convinced that s thofe objections are made either from prejudice or miftaken theory, I view it an obligation incumbent on me to bear this public teftimony in favor of this new mode of treating putrid fevers. In the neighborhood of New-Galway, for feveral ', months paft, an Epidemic Fever, attended with the ■ fame fymptoms as that in Philadelphia, has raged to ■; an alarming degree, and many have fallen victims to • its fury.—To a number of thofe cafes I have been called, and have treated them in the following man- ner, with the happieft fuccefs. ! • In the firft or inflammatory ftage of the difeafe, I j gave calomel from 20 to 30 grains, fufficient to prove 1 cathartic, with a moderate opiate after the operation. ^M The next day, and during the continuance of the ■ fever, gave 2 grains of calomel, morning, noon, and M night, and opiates occasionally—giving frequently an 1 infufion of Rad. Serpent. Virg. in water ; at the \ fame time ordering that wine or lemonade be mixed j in all their drinks. This method purfued in the early ftage of the diforder, a copious fweat will enfue, and \ the patient foon recover. If this happy time for relief ,[ is neglected, the fever puts on the higheft fymptoms of putrefaction, and often terminates in death.—I ought to mention that the fymptoms attending thofe TO THE PUBLISHER. 199 «afes that I have feen, have not been fo violent or fud- t denly fatal as it is faid of that in Philadelphia—owing3 probably, to a difference in the climate. Let thofe who condemn this practice, confider that v the Materia Medica furnifhes nothing that will fo ef- fectually open all the fecretions at once, as Mercury. From thence I think this conclufion is eafy, that nothing will fo fpeedily difcfcarge from the circulation i. whatever matter may happen to be prefent, as this f Divine Medicine. That the art of phyfic may fo improve, that old age fhall be the only weapon ufed by death, is the Sincere wifh of a Servant to the Sick, S. REYNOLDS, I Montgomery, [ Oci. 1795. D d 4 1 ~ -.Uiau,. L .'—r---—7-r——----r R ,E ,M ARKS ON CERTAIN CAUSES OF DISEASE IN LARGE CITIES, AND THE MEANS OF PREVENTING THEM. WRITTEN IN DECEMBER, I795- THE prevalence of the bilious remitting Yel- low, Fever, in this and the neighboring States, for a few years paft, and its fatal effetts, in many of the large towns, render an inveftigation into-the caufes that, have produced, it, highly interefting to the citi- zens of the United States, and efpecially of the mer- cantile towns. The queftion whether the Epidemic, which has proved deftructive in Philadelphia, New-York, New- Haven, Baltimore and Norfolk, was the pffspring of local caufes in our own country, or of imported in- fection, has been much agitated, and to this moment, well-informed men are divided in opinion on the fub- ject. Without giving any opinion at prefent on this point, one thing may fafely be averred, that, whether imported, or generated by local caufes in our own country, the epidemic influence and deftructive ef- fects of this malignant bilious fever, are greatly in- creafed by local caufes, which are wholly within the command of human power. It can be demonftrated to the fatisfadion of all rational, candid men, that whatever be the origin of the difeafe, a great proportion of its deleterious effe&s, is to be fairly afcribed to the 202 REMARKS ON CLEANLINESS negligence of men. This point muft be admitted j for it can be proved by a feries of decifive facts in this city ; and I am informed alfo, by facts in Phila- delphia, Baltimore, Norfolk and New-Haven. This circumftance leffens very much the importance of deciding the queftion, whether imported or not; for if imported, it does not fpread, unlefs its progrefs is favored by unwholefome air in this country. My main defign is to perfuade my fellow-citizens, that the general health of this metropolis depends greatly on their, own exertions ; and that although human power cannot guard againft every inftance of ' difeafe, yet it may prevent, in all cafes, a difeafe pro- pagated by contagion, from fpreading fo as to become a general calamity in a populous city. To enforce a conviction of this kind, I fhall produce only the evi- dence of inconteftible facts or acknowledged truths, \ and the conclufions fairly deducible from them. Difeafes, for my purpofe, fhall be divided in the ; following kinds. I, Thofe which are neither contagious nor epide- ; mic, but generated in particular perfons by local . and temporary caufes, as the peripneumony and j pleurify. j II. Thofe which are propagated folely by conta- % gion, as the fmail-pox. ' ■ IIL Thofe which are epidemic and are not ordi- j narily communicated by infection, as common colds, ; and the intermittent fever. IV. Thofe which may be both epidemic and con- tagious ; as the Dvfentery, Scarlet Fever, Yellow \ Fever, &c. AND VENTILATION. 203 The firft clafs, depending moftly on accident, or the negligence or vices of individuals, are not the ob- jects of my prefent inquiries. The fecond are for the moft part eafily avoided by preventing a communication with the difeafed. Some remarks that will hereafter occur may be applicable to cafes of this kind. The third clafs are for the moft part out of the reach of public regulations. Individual precaution may do much to prevent or mitigate epidemics; but this is foreign to my prefent fubject. The fourth clafs of difeafes are more or lefs under the controul of human regulations, according as they depend more or lefs for propagation on an epidemic imperceptible influence, or on contagion by means of a communication with the fick. The influenza which appeared in 1789 and 1790, was faid to be contagious ; but if this was true, the difeafe could not have fpread by communication with the difeafed; for hundreds and thoufands of perfons were feized in a day, without any intercourfe with each other.-— Its propagation therefore muft have been by means of invifible caufes exifting in the atmofphere. What then are the caufes of epidemic difeafes of the peftilential kind ? It is evident there are two principal fources of dif- eafe.—The firft is the air we breathe—The fecond, our food and drink. Thefe caufes may, and often do, act feparately; and not unfrequently they act jointly in producing difeafe. Irregularities in diet and the ufe of improper food are things that depend moftly on the will of indivi- &c# REMAPS ON CLEANLINESS *LuaIs; and if they produce lefs difeafe at? one time fhan another, it is becaufe the feafon;is more or lefs favorable. The object of my prefent inquiries, is principally to explain the other great fource of pefti- lential difeafes, impure mr ; to demonftrate how much it is in our power to prevent its exiftence ', or lefferiits effects, efpecially in populous cities ; and hence to enfore the neceffity of a total and thorough reform in our police. < 'It is a fact that is evident to all the world, that, the ?natural ftate of air, unmixed with any fubftances ex- haled from our earth, is-the moft. fit for refpiration and perfectly falubrious. Atmofpheric air, even in its, pureft ftate, is found to be a compound fluid.-— IThe parts, when feparated by chymical procefs, are unfit for refpiration, and a portion may be extracted rfrom the pureft air, which is inftantly fatal to the life of animals. Chymifts fuppofe they have afcertained | the proportion' of the parts of good and bad air, which exifts in the natural ftate of the atmofphere*. ■ "This is not material to my purpofe. It is fufficient < ■for the purpofes of common utility, to know that air is falubrious when it is pure ; that is, in its natural (late, unmixed with effluvia from the furface of the 1 earth—and on the other hand, that the air is un- J -.wkoLefome and.unfavorable t0 nre> ln proportion as J it is impregnated with morbid exhalations from the ■ earth. m ; The, morbid exhalations .which affe£l the, air, pro- \ _ ceed moftly,rfrom , fermeritjng animal „ and vegeta- ;bie fubftances. rJn,what proportion thefe fubftances •< * See an ingenious little treatiie on Contagion, lately pu'o- fl fliftxcd„ by, Pr. S. L. Mitphill; in which, notvfithftanding the 1 technical terms employed, a common reader may find much m- ftraction. AND VENTILATION. 205 produce fuch noxious effluvia;, is not material; a? it- is a given point that both may produce them. That ftate of animal and vegetable fubftance which feems to generate the poifonous air in greateft quantities' and with moft rapidity, is the ftate of putrefadion ; which is the natural procefs by which fuch fubftances are decompounded and refolved into their original; component parts. Putrefaction is carried on by air, heat and rttbif" ture. Without air, all a&ion ceafes in the animal and vegetable world; and the greater the heat and moifture to which fuch fubftances are expofed, the more rapid will be the procefs of putrefaction. As all animal and vegetable fubftances contain a quantity of noxious matter; and as they muft be continually decaying and putrefying, in greater or lefs Quantities, on the furface of the earth ; and as t they necelTarily difcharge, during this procefs, a poi- fonous effluvia into the atmofphere; it becomes a fe- rious queftion, efpecially for the inhabitants of large towns, and in the neighborhood of extenfive marfhes, by what means they can avoid the inconve- niences and fatal effects of fuch an atmofphere. Let 1 us then attend to the following considerations. The exhalations of a deleterious kind, like fhe ef- fluvia of all other kinds, proceed from certain objects . as from the centre of a circle ; and if not forced from | their direction by winds, probably diverge in ftraight ' lines. Near the objects from which they proceed, ; they are in their moft denfe or concentrated ftate ; \ and as the objects ufually lye on or near the earth, the air near the earth muft be impregnated with the greateft quantity of this morbid matter. Perhaps alfo the fpecific gravity of this foul air may be 20O\ REMARKS ON CLEANLINESS greater, than of pure air. But it is probable that it Is capable of rifing and diffusing itfelf in the atmof- phere ; and that it becomes attenuated by occupying a larger fpace in the common air, until it is tho- roughly incorporated. In this manner, it is moft ,■ dangerous, becaufe moft concentrated near the earth; J and at a diftance, is more harmlefs. ,/ The means of avoiding the injurious effects of thefe ) exhalations are various. • I. By removing the animal or vegetable fub- ftances, which generate noxious air. This is an arti- cle of infinite confequence to cities. II. When the fources of poifon cannot be re- moved, as with refpect to large marfhes which can- not be drained, the obvious method of avoiding the ill effects, is to avoid, as much as poffible, breathing. f[ the air in the neighborhood. Farmers would do- ' well to fet their houfes as far as is poffibly confiftent . ■ with their bufinefs, from fuch low grounds. III. When people neceffarily live in places where J large quantities of morbid effluvia ufually impregnate j the atmofphere, ventilation of their ftreets and houfes > is among the moft effectual means of preventing | the concentration of the poifon and its fatal, confe-. ,a| quences. 1 So far as regards the police of a city, the whole / j doctrine of preventing or mitigating the injurious ef- fe£ls of bad air, is comprehended in the following articles—to remove the fources of the poifon, or to diffipate it as much as poffible. To remove the fources of the evil, infinite care fhould be taken in building cities, to leave no low I AND VENTILATION. 207 grounds or hollow places among the buildings, as receptacles of water and filth. The back yards fliould, in every cafe, be raifed above the pavement of the ftreets, and the ftreets fhould be fo raifed, as to give a confiderable defcent into the adjoining river or fea. No trouble or expenfe will juftify a neglect of this regulation. The health and the lives of citi- zens abfolutely depend on this precaution. If the land in the rear of the building lots is naturally lower than in front, it fhould be raifed by carting in earth. It fhould be an article of the police of every city, that no man fhould erect a houfe, without at the fame time, raifing the back yard, to give a defcent in- to the ftreet. The yard fhould alfo be paved, if a- mong other buildings in a compact part of the city ; and no filthy water from the houfe fhould be fuffered to lodge in back yards. People fhould learn that it is not large piles of animal or vegetable fubftances alone, that generate foul air; but every fmall fiib- flance, and all the water that has been ufed in a fa- mily, add to the fources of this evil. Water itfelf may be abforbed in the earth or evaporate; but any filthy fubftance it may contain, lodges on the furface of the earth, expofed to the action of the fun, and furnifhes a portion of poifonous effluvia. Hence in cities, fmooth pavements, though they may augment the heat of the air in fome fmall degree, contribute not a little to preferve a pure air, by facilitating cleanlinefs. And it is a remarkable fact that the in- habitants of the fuburbs or fkirts of many of the large towns in America, who live beyond the pave- ments, are much more fubject to the common au- tumnal complaints, than thofe who refide within the pavements. Water is perhaps the beft purifyer of the houfes and ftreets of cities, as well as of infected clothes.— E e 208 REMARKS ON CLEANLINESS The ufe of water cannot be too liberal; but care fliould be taken that none of it remains to ftagnate about or near buildings. Water imbibes the poifon of foul fubftances, and therefore when houfes, back vards and ftreets are wafhed, the water fhould be enabled, by fuitable channels, to run off into the fewers or adjoining river. If the natural furface of the earth is too level for this, no pains fhould be fpared to remedy this inconvenience by artificial ele- vations." It is no excufe for neglecting thefe things, to fay they are expenfive ; becaufe they cannot be fo expenfive as epidemic difeafes. The lofs of bufinefs for one feafon, in fuch a city as Philadelphia or New- York, would build all the ftreets in this city, where the fever has been moft fatal*. But when we take into confideration the lofs of life, the tears, the dif- treffes of bereaved parents, and of helplefs widows and orphans—the idea of expenfe, for the purpofe of preventing fuch calamities, lofes all its terror.— Labor and perfeverence will conquer all difficulties of this kind ; and if all poffible means of rendering ci- ties healthy are not ufed, why are they built at all ? Why fhould cities be erected, if they are to be only the tombs of men ? A frequent recurrence of malig- nant and fatal epidemics will befides leffen the bufi- nefs of a town, and this finks the value of real eftate. It is therefore the proprietor's interefi as well as his duty to attend to every circumftance that can infure the health of his tenants. But as among a multitude of people, the artificial caufes of difeafe muft be numerous, and much dirt and filth will be found, to produce impure air, what- ever pains are taken to preferve cleanlinefs; it be- * Half a million of dollars is probably a low eflimate of the lofs incurred by New-York the laft feafon. AND VENTILATION. 209 comes a ferious inquiry how ftreets and buildings may be beft conftructed for ventilation. As water abforbs the poifon of filth or wafhes it away ; fo wind diffipates the morbid effluvia, and renders it altoge- ther harmlefs : or at leaft diffufes it fo as to leffen its ' action upon the fyftem. If we examine the progrefs of the late fever in this city, we fhall find its ravages in a dire£l proportion to the want of cleanlinefs and i ventilation in the feveral ftreets and houfes. To know how much depends on a free air in the cure of fevers, moft perfons need only to attend to the facts within their obfervation. But this is a circum- ftance of fo much importance to a city, that it de- ferves particular confideration. Air, as well as water, is a fluid, which, by the laws of nature, is kept in almoft continual agitation. > Its natural ftate, as before obferved, is perfectly falu- k brious ; that is, fitted for the purpofe of preferving life and health. Whatever poifonous qualities it may [ contain, it receives them fromfubftances within the hu- man body, or ort the furface of the earth. But it is a | law of fluids to purify themfelves by motion. Thus whatever impure qualities the air may receive from putrifying fubftances, and which may be raifed by heat and float in a ftagnant air, may, by violent agi- tation, either be fo attenuated or diffufed, or fo inti- mately combined with other parts of the air, as to be rendered totally harmlefs. Whatever therefore tends to obftruct the motion of the air near the earth ; that ' region of air which men conftantly breathe ; re- l ftrains, in a greater or lefs degree, the natural ten- ; dency of the air to purify itfelf. Hence the infinite I importance of attending to the means of giving a free \ current of air through houfes and the ftreets of a po- pulous city. 2IO' REMARKS ON CLEANLINESS The ftreets of a city fhould, if poffible, be ftrait.— The flale notion of cenfuring uniformity in a city, is j worthy only of weak minds. Crooked or winding ftreets tend to break the force of the wind ; as with . a ftream of water, which is retarded at every bend. This article however is not of the firft confequence. ? It has been doubted whether wide ftreets in a large m town are very beneficial; as the action of the fun on j the pavement is violent, and the heat is increafed, and 1 as the quantity of fhade is lefs in proportion in wide 1 ftreets than in narrow ones. But wide ftreets, if M kept clean, are doubtlefs the moft healthy, as they ad- 1 mit a larger quantity of pure air, and a more free cir- culation. Another article in the laying out of ftreets for healthinefs, is, a fuitable elevation of the parts diftant from the fewers or river, to give a defcent for the water to run off with fome force and rapidity. A moderate elevation is not fufficient; for though, in j fuch a cafe, the water itfelf may drain off liowly, yet J it leaves moft of the filth behind, which is the fourCe I of poifon to the inhabitants. In this particular, 1 Front-ftreet and Water-ftreet, in this city, are very j ill conftructcd. The natural pofition of thofe ftreets, I which are made along the fhore of the Eaft River, is nearly on a level. It was the bufinefs of the police M to remedy this, in the mode of paving. Two obvious modes of preventing the inconveni- 1 ences of level ground, fuggeft themfelves. Firft to 1 raife the middle of the ftreet, then to give the whole I a more round or fpherical form, than is neceffary on } a declivity. Where a confiderable declivity occurs, the water will run off with force, whatever be the ; form of the pavement. But on a level, fome artifi- \ cial elevation muft be contrived. On a declivity, the ; AND VENTILATION. 211 form of the pavement fhould be the fection of a large circle—on level ground, the lection of a fmall circle, is a better form. The fecond improvement in making ftreets on le* vel ground, is to raife the land in the centre, between two gutters or fewers. Thu3 for inftance Water- ltreet^between Pine-ftreet and the Fly-market, fhould be railed much higher than at prefent, in the central point between the two ftreets. The inconvenience of an elevation of two or three feet in fuch a diftance, is trifling, when put in competition with cleanlinefs. Perhaps alfo fmooth gutters along the fides of the ftreets, next the foot walk, might be made of hewn ftone, and fo laid as to be durable. This would amazingly facilitate the cleaning of ftreets which are nearly level. Another article in conftructing a city for health, is, that as few ftreets as poffible fhould terminate within the city; that is, inclofed, at the ends as well as fides, by ranges of buildings. Wherever a ftreet terminates by a block of houfes, the circulation of air is obftructed. Violent winds indeed penetrate into every place; but moft of our fummer winds are light, and in the fultry feafon, when ventilation is moft wanted, becaufe the exhalations of a noxious quality are moft confiderable, there is very little wind in the open country ; and in the confined ftreets of a city, none at all. Lumber-ftreet, is an example of a ftreet terminated by three flory buildings in Liberty-ftreet. There are many others of the fame kind, and fome with no di- rect opening to either river, as Garden-ftreet and Batavia-ftreet. This circumftance makes no fmall J 212 REMARKS ON CLEANLINESS difference in the free circulation, and cohfequently in the purity of the air*. In the conftruction of dwelling houfes, equal at- tention is required to the form and" pofition, in order to promote ventilation. Under ground ftories for the habitation of families, it would be well to prohibit altogether. As work-fhops they are lefs pernicious; but are generally unfavorable to health. In fome cafes, rooms partly below ground are fo fitu- ated, as to admit a current of air through them. In fuch cafes, they may be occupied with more fafety. The circumftance of admitting frefh air through rooms by oppofite correfponding windows or doors, is one that ought never to be neglected, in low fitu- ations and crouded places. The difference in the circulation of air, is immenfe, when the air can pafs through a room in a direct line. Side doors and windows do not effectually anfwer the purpofe; and when there is no opening into a room, but on one fide, there can be very little circulation. It might be well worth the attention of people who build houfes, to confider whether it would not favor health * Let a dam be ere£ted five feet high, acrofs a ftream of ten feet depth. This dam would check the current near the bottom j of the river, for a confiderable diftance. The fame is true of air, in a lefs degree. Every perfon has obferved the effect of friction in retarding the current of a river. The current near the fides and bottom is flc.ver than in the middle ; by means of the friction of the water ag:1.:-ift the earth.- A remarkable proof of this is, that the tide in riv•:••-- no vs and raifes the water 6 or 8 inches, before the ebb cur- rent has done running on the furface of the water. The flood tide .-r.eets with lefs refillance fi-.>m the flow under current, than from the rapid current above—it checks the under current firft, and thus raifes the water, whii" the ebb current on the furface is yet runiiiiig-. AND VENTILATION. 213 materially, to conftruct doors or windows between the front and back rooms of their houfes, in fuch a manner, that they might be ufed in fummer, but clofed and concealed in winter. In many fituations, this arrangement would prove highly agreeable, and contribute greatly to health. If the foregoing principles are juft, it is worthy of our attention to compare the actual fituation of New- York, as it relates to the means of preferving health, cleanlinefs and ventiliation. The natural fituation of a great part of this city, is as well calculated for falubrity of air, as it is poffi- ble to conceive one to be. The form of the Ifland is adapted for cleanlinefs in a remarkable manner; the land gradually rifing from each river, the filth is, by every rain, wafhed down the declivity on each fide towards the river, and where it is not obftructed in its paflage, by fome artificial means, is carried into the water and fwept away by the tides. The city is ; open on the fouth weft point to refrefhing breezes from the bay ; and the reftriction which prevents the corporation or citizens from ever converting the walk at what is called the battery, into ftreets and houfe lots to be inclofed and covered with buildings, j has infured the lives and health of thoufands of citi- izens. Frefh air enters Broad-way, Greenwich- 1 ftreet, Broad-ftreet, &c. and penetrates freely into the city; ventilating thofe fpacious ftreets and diffi- ! pating the noxious air neceffarily generated in a large ' town. On the weft, the ftreets which crofs the Ifl- and, are open to frefh air, from the Hudfon, and the ftraight direction and the breadth of thofe ftreets, confpire with the declivity of the ground, to give all that part of the city, the advantage of ventilation and cleanlinefs. 214 REMARKS ON CLEANLINESS On the eaft fide of the Ifland, the declivity of the ground is favorable to cleanlinefs, from the height of the land to Pearl-ftreet, the laft ftreet erected on the natural earth. Water-ftreet and Front-fireet are built on made land—the water every tide penetrates, by fubterraneous paffages, to the cellars in Water-ftreet, and what is perhaps worfe, the ftreets are fo level, \| that not only the filth made on them, but great part i of what is brought down from the higher land in John-ftreet, Maiden-lane, Pine-ftreet and Wall-ftreet, ' lodges upon the pavements or in the fewers. In paving and building on this made land, no effectual provifion was adopted to carry off the water and filth; and the inhabitants feverely feel the confequences of ; that neglect. Here then we find, if not in all cafes the fources* yet the peculiar region, of fatal maladies. Here dif- eafes of a malignant kind in hot weather firft appear, and from fome point, take their departure and ipread : defolation. If we proceed further northward, we fhall find, in what was called the Swamp, a ftill more fatal neglect of the means of preferving health. The ground now covered by Roofevelt-ftreet, James-ftreet and J Catherine-ftreet, extending from the Eaft River W towards the Tea-water Pump, was a few years ago M covered with a pond of water. The ground is arti- 1 ficial; and not only fo, when the ftreets, a few years ■■ ago, were paved, they were raifed from two to four feet above the foundation of the original houfes. The back yards are few of them paved, and being lower than the ftreets, they are the refervoirs * of every fpecies of filth. AND VENTILATION. 215 So far as regards falubrity, this part of the city is I moft unfortunate; indeed it is fcarcely poffible to | conceive of a fituation worfe calculated for preferv- f ing the lives of the inhabitants. !The natural fituation of this quarter of the city is not favorable for cleanlinefs and ventilation. A ilraight line from the Battery to Corlaer's hook would pafs by Beekman's-flip, Peck-flip, New-flip, &c. at feveral hundred feet diftance ; the fhore being a curve. By this means, the part of the city forming this curve, is fhielded from the dire£l courfe of the wefterly winds, the moft falubrious that blow on this continent and which prevail nine months in the year. On the north weft, the higher ground and buildings I prevent the direct accefs of the wind ; fo that that part of the city, which is the oldeft, belt-fettled, and where filth is moft apt to collect, has the leaft ad- vantage of free air. The direct courfe of the wind being broken by the higher ground on the north ' weft and the fouthern point of the ifland, the pure air from thofe points feldom blows with violence along the eaflern fhore, and the light breezes of fummer, inftead of fweeping currents, afford httle more than gentle eddies that are infufficient to pu- rify the atmofphere which the citizens breathe. The high ground in the rear of the fhip-yards and above George-ftreet are very injurious, in prevent- ing ventilation. The land is nearly on a level with * the chimnies of the houfes from George-ftreet to l^ Roofevelt-ftreet. This breaks the current of air in m almoft every direction; for it has been before ob- f jferved, that the under current of air is checked by objects to the height of thofe objects. Ff 2l6, REMARKS ON CLEANLINESS Thofe natural difadvantages of fituation are not remedied by the mode of building and paving the ftreets below. The ftreets are nearly level; the back yards are unpaved and receive every fpecies of filth, which accumulates the whole year, and in fum- mer muft fupply a prodigious quantity of foul exha- lations. It is impoffible for the inhabitants of fuch ftreets to be healthy in a hot feafon. The eaflern part of Water-ftreet is in a fimilar ftate. The pavement is raifed above the firft floors of the buildings and above the ground between that ftreet and Cherry-ftreet. Of courfe water and filth collect in the rear of the buildings and in the cellars. The wharfing is equally bad ; fome of the wharfs only half finifhed admit the tide; but prevent the filth received from the ftreets and houfes, from being fwept away. This is the cafe about the place where the fever appeared the fummer paft. The wharfs fhould be made folid and complete and well paved— folid to admit of the leaft poffible fubterranean filth and itagnant water, and well paved to carry off what is formed on the furface. Such are the facts relative to the fituation of this city, as adapted to cleanlinefs and ventilation. A great portion of the city is high, cleanly and well_&2 ventilated—but fome parts are low, level, and dirty, and covered from wefterly winds. The former has invariably efcaped the ravages of epidemic bilious fevers, and the latter has repeatedly fuffered by their fatal effects. Let any candid man walk over the city, and examine the fituation of each ftreet, and he will find that the epidemic has been fatal, in a very j] exact proportion to the caufes of difeafe which have been defcribed. AND VENTILATION. 217 Before I conclude this fubject, I would make fome remarks on the manner of conftructing the common fewers, as alfo the wharves and docks. The principal fewers in the city, fuch as thofe In Broad-ftreet, Fly-market and Burling-flip, are built on ground, fubject to a flux and reflux of tide. If the tide penetrates through them, it carries back the filth which is received from the ftreets, and pre- vents it being fwept into the fea, for 6 hours every flood. If any part of the fewer is above high water, a great portion of the filth will be met by the tide, and lodged ; and, what is worfe, if the fewers are wholly above high water, and not waflied by the tides, and if they are nearly in a horizontal pofition, great quantities of filthy putrefying fubftances will always be collected in them. In all thefe cafes, a fetid air is generated and emitted from thefe refer- voirs of impure matter. Thefe confiderations fuggeft the impropriety of all fewers under ground, unlefs in places where tides or running water conftantly wafh them clean. If all the water of a city is drained off on the furface of the earth, any collection of filth, by means of fudden fhowers or other caufes, is vifible, and may be eafily removed. Never was a greater miftake than conftructing an arched fewer under ground, in Fly-market. The land in Maiden-lane is fo high, that it would have been very eafy to conduct the water above ground into the dock; and nothing could have been more cleanly and falutary, than to have had the market wafhed by the copious ftreams of water which are collected, every fhower, from William-ftreet and Liberty-ftreet, and united juft above the market. It Jfeems as if nature had contrived a fituation in tha 218 REMARKS ON CLEANLINESS fpot, for a clean wholefome market, and that all the ingenuity of the corporation had been formerly ex- ercifed, to defeat her beneficent intentions. So well adapted for this purpofe have been the means ufed, that the water is directed under ground, at the very point where it is moft wanted above ground. As all the water is thus carried off, and as the ftreet is nearly level, all the filth of the dirtieft place in the city, is left as a nuifanceto annoy half the inhabitants of the city, who are obliged to refort to that market. As if this was not enough, a floor is made to the market, and fo loofely put together, as to fuffer filth and offal to get beneath the boards, where it is out of the reach of any flight attempts to fweep the mar- ket. This is an inexcufeable fault—becaufe the ex- penfe of removing the floor, and laying a fmooth brick pavement, which is eafily wafhed and always firm, is too'inconfiderable to be noticed. The cleanlinefs of the Philadelphia market, which is thus paved, fhould have fuggefted this improvement, long before this time*. Equally ill-conftructed are the wharves. Docks, in which all manner of filth is collected, are left dry at low water, which never ought to be the cafe. For although the water of the fea, and pure earth covered with it, are not unwholefome, yet when mixed with other fubftances, the compound may prove highly noxious. It appears to me that the docks fhould be filled out fo far as that the earth fnould, at low water, be entirely covered. The wharves fhould be made as folid as poffible, to pre- vent water from penetrating and flagnating in them, or conveying into the interior ftrutture of them, ve- * Since writing the above, this market is undergoing a ma- terial alteration. AND VENTILATION^ 21^ getable and animal fubftances which may lodge and putrefy. They fliould alfo be fo conftructed on the top as to be eafily kept clean. The deep holes and miry places about our wharves in rainy weather, are as unhealthy in hot weather, as they are inconve- nient at all times. They are in many places fo nar- row, as to endanger the legs and lives of men among the carts, hogfheads and bowfprits, and in the hur- rying feafon of autumn, it is not too much to calcu- late that ten per cent, of the labor of men employed on them is loft by their interfering with each other. What complete remedy can be fuggefted for thefe evils, I will not undertake to decide. It is a common concern, and among the citizens who are interefted in a general and thorough correction, fome will be found to point out the principles. It feems obvious however, that a total flop fhould be put to extending the made-ground into the rivers. This artificial earth is always porous ; it admits and retains water; of courfe all cellars in fuch ground are damp and unwholefome. Perhaps it might be well to fill up the docks, and give the front of the folid wharves a ftrait direction—leaving no ground bare at low water ; fo that every fubftance, waflied or fwept into the water, fhould be floated away.— The wharfing might be extended to any convenient diftance into the rivers, by erecting piers, connected by bridges. It appears, however, proper, that all the wharves fhould be permitted to extend only equal diftances—the fame of the flores on the wharves— they fhould prefent a uniform front. This would render them all more airy and healthy ; and no man could obftruct his neighbor's air or view ; a matter of no fmall confequence, as it regards pleafure and health. 220 MEDICAL OBSERVATIONS. It is a fact clearly afcertained, that the procefs of vegetation contributes to the falubrity of the air.— The more trees, grafs-plots and flowers can be cul- tivated in a city, the more healthy. All broad ftreets, will admit the growth of Trees, and thefe are as ornamental as they are ufeful. The objection ' to them in cities on account of their obftructing the _, ufe of engines in fires, is not of much weight. A cafe of this kind can rarely happen ; and when it .' does, an ax or two will level the tree almoft in a moment. Befides, the objection is more than ba- lanced by the fecurity they afford one half the year againft fire. A tree, when full of green leaves, may break the force of a fire and fave a houfe. An inftance like this happened in Bofton, where a thick coat of creepers on the fide of a houfe next i the approaching fire, fo far broke the flames, as to I be a principal means of faving the building. It is j ufeful therefore to encourage the planting of trees ' in this city, in every fituation, where commanding ' reafons do not prohibit it. —s 1be following Remarks are judged worthy of a place in J this Colledion. a From the French and American Gazette. '1 MEDICAL OBSERVATIONS. 1 The inhabitants of New-York, as juftly alarmed aj the Philadelphians were two years ago, at the ha- ^ vcc of difeafe, faw, if not with a jealous, at leaft with an amazed eye, a Frenchman dwelling under the fame ; roof with himfelf, enjoy the pureft health, whilft he ! fell, as it were, ftruck with a thunder bolt, without i MEDICAL OBSERVATIONS. 221 being able to experience any relief from medical i fkill; we, ourfelves, furprifed at this fingularity, have fcrutinized into the wonderful fecrets of nature, as i far as can be allowed to an human, and of courfe a | weak eye ; and we attributed the difference to the i manner of living, cuftomary to both nations, and I their treating themfelves. The more we examine the modes of living of an American and Frenchman, whether indifpofed or in good health, the more we perfift in our fyftem, and in the idea that the American cannot totally preferve himfelf free from this raging fever, which commonly breaks out in hot weather, but by following another regimen directly oppofite to that which he has till now ufed. f Although the American feems commonly to enjoy the beft health, though his high color announces the ftrongeft conftitution, yet we are much inclined to think that he would not run fo many rifks in the fummer time, were he to live more foberly during the other feafons; were he to live upon more whole- fome food ; were he lefs fond of ftrong liquors, tea, and green fruits, and would he make a frequent ufe ■ of baths and lotions; which are as wholefome for the inteftines, as neceffary for exterior cleanlinefs. We will not follow the Americans through the paths of private life; but we fhall fay that, in general, temperance is not obfervable among them, nor that moderation of which the French daily reap the ad- vantage ; the latter relifh Burgundy and old Bour- deaux wine, and feldom allow themfelves to drink fpirituous liquors ; while the former difapprove of Claret, as too weak, and prefer Madeira, Sherry, j Port, Rum, and Gin^ which muft, of courfe, inflame 222 MEDICAL OBSERVATIONS. and throw the blood into a fermentation. Notwith- standing this, we fee Americans, who fay they have been advifed to ufe them, efpecially during the difor- der, in order to give tone to the ftomach. The French never drink any tea,unlefs they feel their ftomach uneafy. In the morning and in the evening, the Americans feem to fwim in tea, which is fo ftrong, that an Englifh tea pot would make as many as twen- ty, according to the French fafhion. Should what has been faid by fkilful and learned Doctors be true, that tea is one of the moft corrofive vegetables, the juice or effence of it muft of courfe make a flow but ftrong impreffion on the nerves, and occafion the diffolutionofthe blood. It is likewife cuftomaryto eat with their tea, heavy cakes of all kinds, and toafts which are not reckoned to be good unlefs they are thickly covered with butter; which increafes the bilious mafs of humour. We fhall not repeat the obfervations which we have heretofore made, upon the averfenefs the Amer- icans feel for foup and reftorative broths, on their eating their meat running with blood, with fcarcely any bread, and plenty of heavy potatoes, the only\ vegetables which are feen on their tables; whiift the French always give the preference to vegetables, and efpecially to thofe which are light and wholefome. But we cannot help obferving, that in the months of May, June and July, the ftreets and markets were feen in the morning furnifhed with an immenfe quantity of fruits, the moft part of which are either green or unripe. In the evening ail thofe fruits have difap- peared and have been eaten ; hence, bloody fluxes, dyferneries and bad chyles,- which unwjiolfome food muft undoubtedly produce, MEDICAL OBSERVATIONS. 223 As to baths, baths of cleannefs, injections, &c. there are few French, in the leaft careful of their health, who do not make ufe of them. > The Americans, far from practifing thofe ufeful and wholefome tokens, look upon them as ridiculous and unbecoming. It is no longer furprifing that Americans, heedlefs of their health, living on unwholefome foods and drinking heating liquors, fhould prove fo little dif- pofed to refill the impreffion of fcorching hot weather, which opens the pores, and occafions, if we ".- may be allowed the expreffion, a continual depreda- tion on the vital principles, through a thoufand iffues, , always open. It is not to be wondered that heat and dampnefs, which on this continent more rapidly fucceed each other than in any other climate, fhould foon bring into a ftate of fermentation, humors im- pregnated with fo many principles of putridity. Will any one wonder at feeing the unfortunate feized with the fever, fall fo fuddenly victims to it, when they are feen to fwallow remedies which, far from keeping down and cooling the fermentation, increafe f *it 5 when they are feen undergoing copious bleed- | ings, ftoring in emetics, bark, Madeira, and other I fpirits called tonical, producing in the body the ■ fame effects as oil or fire ? Finally, we fee when ■thefe unfortunate people are left^by themfelves, de- ■ferted, and given up by their neareft relation, whom Ha panic keeps as far from them as from perfons in- Rfecled with the plague, forrow'and defpair, much H^nore than the moft violent remedies with which they ■are treated, hurries them to an unavoidable death. I For thefe two years, the French have been no- l* ticing thefe falutary obfervations to the Americans, ■"-4 OBSERVATIONS FROM THIt who liften to them with coolnefs, although many of them perceive the juftnefs of thefe hints, but habit is a fecond nature. As foon as the epidemic feems to abate, as foon as the coolnefs of the weather brings back the hope of feeing it difappear, they will haftily re- turn to their homes, go on with their old habits, their ufual way of living, and on the fmalleft indifpofition,] fend for their dear doctor, who exclufively is mafter of their confidence. We are acquainted with French phyficians, who at Philadelphia treated with fuccefs two hundred perfons taken with the diforder, and thofe very fame perfons have not afterwards vouch- fafed to fend for thofe to whom they were indebted for their lives, even to be bled by them. The following Obfervations from the Manchefter Mer- cury, contain ufeful hints, and cannot be inapplicable to many fituations in the United States. Manchester Mercury, Feb. 2. Mr. Harrop, After having endeavored, for the laft four years, to call the public attention to the dangerous fituation of the poor in this town and neighborhood; it gives me the higheft fatisfaction that a number of the moiij refpcetable inhabitants have been induced to adopt j the ideas which I had fuggefted, refpeding the regu; lation of Cotton Mills, and the erection of Fever Wa-ds. As it is of great importance, that a know- ledge of the facts, and reafoning, on which their de- termination has been founded, fliould be extenfively^ communicated, you will oblige me by^ mferting the following extracts from a Memoir, which I drew up at the defire of the original meeting. I am, Sir, your very obedient fervant, Da-4on.firecU ? J- FERRIAR. * Jan. 18, 1796. 5 MANCHESTER MERCURY.. 225 TO THE GENTLEMEN MEETING AT THE BRIDGEWATER ARMS. Gentlemen, At the requeft of fome of your number, who ori- ginally propofed this meeting, I fubmit to your con- fideration a few remarks towards the formation cf a Board, or Committee for fuperintending the health of the manufacturing poor in Manchefter and Sal- ford. A principal object of this Committee, muft be that of diminifhing the frequency of the Epidemic Fever, which has fo often alarmed us in this place, which is now very prevalent in fome parts of the town, and has fpread itfelf to a very unufhal extent in fome of the neighboring towns. The circum- ftances which produce and propagate this difeafe, , feem to require more immediately the interference of * a public body, and thefe once remedied, the general i health of the poor muft be greatly improved. Hav- ing already publifhed my fentiments pretty full on this fubject; I fhall remark, without entering into any reafoning, that the principal fources of fever among our poor, are lodging-houfes, cellars, cotton- mills, and the incautious intercourfe of the poor with each other,-tn places infected. 1. Refpecting lodging-houfes, I have obferved elfe- where, that the moft definable means of prevention, would be to fubject them to licenfos, which would bring them under the controul of the magiftrates.— At prefent, as the town is much lefs crouded than it was in 1792, the mifchief arifing from thefe houfes ;■ is lefs ; and until the Committee can acquire the proper powers ; it would perhaps be fufficient to be k at the expenfe of white-wafhing fuch as fhall be re- ported to be infected and dirty, or where they are 226 OBSERVATIONS FROM THE found to be over-crouded, to prevail on fome of the lodgers to remove, which may be readily done. 2. The number of damp, and very ill-ventilated cellars, inhabited in many parts of the town, is a more extenfive and permanent evil. It may be neceffary ,, to. explain to gentlemen who have not vifited fuch j places; that they each confift of two rooms under ?| ground, the front apartment of which, ufed as a t kitchen, though frequently noxious by its dampnefs and clofenefs, is greatly preferable to the back room; the latter has only one fmall window, which though on a level with the outer ground, is near the roof of the cellar ; it is often patched with boards or paper ; , and, in its beft ftate, is fo much covered with mud, as to admit very little either of air or light. In this cell, the beds of the whole family, fometimes confift- j ing of feven or eight, are placed. The floor of this 1 room is often unpaved ; the beds are fixed on the 1 damp earth. But the floor, even when paved, is al- I ways damp. In fuch places, where a candle is. re- J t quired even at rtoon-day to examine the patient,I have feen the fick without bedfteads, lying on rags; they { can feldom afford ftraw. " This deplorable ftate of mifery becomes frequently the origin, and certainly fupports in a great degree the progrefs of infectious fevers. I have been able < in many inftances to trace the infection from cellar to cellar, and to fay where it might have been ..' flopped by prudent management on the part of the infecled family. But it is likewife very difficult to eradicate the fever, when it feizes a family thus fitu- ated. It generally attacks them all in fucceffion, j and the .convalefcents, from their confinement in the midftrof infection, have frequent relapfes, attend- ed with increafing danger, fo that the difeafe conti- , MANCHESTER MERCURY. 227 nues in the fame fpot for feveral months together.— The recovery even of thofe who do not relapfe, is alfo tedious and imperfect, beyond the conception of any who have not experienced cafes of this nature. The want of proper nurfes muft be added as none of the leaft evils attending this unfortunate clafs of people. I have no hefitation in afferting that many lives are annually loft, from this caufe alone. It is extremely- difficult at prefent to procure a nurfe of good cha- racter upon any terms ; and it is often neceffary to employ perfons on whom little dependence can be placed, that the fick may not be entirely deftitute of affiftance. Great advantages would therefore be derived from removing the infected, and in fome inftances, perhaps, the whole family, from fuch dreadful habitations as I have defcrlbed,into a clean, airy houfe, which fhould be provided by the Committee, till their own cellars could be wbite-wafhed, and fweetened by flacking quick-lime on the floors. It is a queftion for the deeifion of the Committee, whether they would pre- fer renting a houfe, or building a fever-ward for this purpofe. I confefs, that I fhould incline to the let- ter, for thefe reafons: 1. In the erection of a fever-ward, fituation, air, and convenience would be better confulted; in renting a houfe, fome of thefe very important objects raight be unavoidably fuperfeded. 2. Upon fuch a permanent eftablifhment, one or more women of decent character might be induced to undertake the office of nurfes. 3. By thus bringing the word and moft neglected cafes under one roof, the chance of fpreading infec- 228 OBSERVATIONS FROM THE tion would be diminifhed, while attention to the pa- tients on the part of the nurfes would be better fe- cured, than if the patients were difperfed in different j houfes, as, in reality, it would be very difficult to ob- 3 tain a complete houfe, upon any rent, for fuch a pur- J pofe. | To explain this obfervation, I muft beg leave to §| repeat a circumftance which I have flated in my laft 1 volume of Medical Effays. Previous to the building of our difpenfary, when a patient happened to be feized with an infectious fever in the Infirmary, the difeafe was apt to fprcad to an alarming degree, fo as to require a general difmiffion of the patients. But fince a few rooms have been added to the Difpen- fary, for the purpofe of fecluding perfons thus at- j tacked, from the reft of the patients, though bad fe- vers have been accidentally introduced, yet by remov- ' ing the patients on the firft attack into the fever-ward, the difeafe has always been prevented from extend- ing, without the neceffity of difmiffing a fingle patient. In like manner, I conceive, that by building a fever- ward in each of the Infirmary diftricts, and removing into them the worft cafes, from the worft houfes, the progrefs of infection would be materially checked, and a great quantity of difeafe and mortality would annually be prevented. This plan would alfo give Jfl additional fuccefs to the Infirmary Phyficians. It ^Lm would add the chances arifing from cleanlinefs, free ■ ventilation, and careful nurfing, to the efficacy of ■ medicines. m 4. In a feparate building, the accefi of unneceffary 1 vifitors would be better prevented. It may give the ■ Committee a clearer idea of the extent of this danger, ™ to mention, that an elderly woman, juft recovering j from the fever, informed me, that fhe had fifteen j MANCHESTER MERCURY. 229 children, all fettled in the town, and all of whom had undergone the fever within thefe two months. At prefent, perhaps, it would be moft expedient for the Committee to try the effect of a fingle fever- ward, in fome part of the town where infection more frequently prevails. In a town like this, fuch build- ings can never become entirely ufelefs, even if the plans of the Committee fhould extend to the length at which I have hinted. The want of proper fewers in feveral of the ftreets, and the offal of flaughter- houfes, left to putrefy before the doors in feveral places, are nuifances which deferve the ferious atten- tion of the Committee. 5. On the fubject of the propagation of infection in Cotton Mills, it may be neceffary to obferve, that although it has been fuppofed that fever may be im- ported in the Cotton, and though this opinion does not feem improbable in itfelf, yet no direct proof of fevers originating from this fource has ever been ob- tained. On the appearance of the prefent Epidemic at Afhton, an alarm of this kind was fpread, becaufe the fever broke out in the picker's room of a manu- factory there; but I am informed, from very re- fpectable authority, that the infection was actually carried thither from Manchefter, by a girl who went to be employed as a picker at Afhton. I apprehend that the mifchief arifing from fome Cotton Mills, as they are at prefent managed, refults from I. The cuftom of working all night. II. Negligence in wafhing the floors and frames. III. Negligence reflecting the perfonal cleanlinefs of the work-people, and efpecially of the children. 230 OBSERVATIONS FROM THE IV. Imprudence in permitting convalefcents, or perfons coming from infected houfes, to refume their work, with their clothes faturated with infection. V. Want of proper ventilation, particularly during the night labor, when the air of the room is render- ed additionally impure by the candles. With regard to the three firft articles, I am uncer- tain how far the Committee could with propriety in- terfere. If the proprietors and overfeers of manu- factories could be interefted in the views of the Com- mittee, very advantageous regulations might be form- ed. The cuftom of working all night totally fruftrates every attempt to ventilate the mills thoroughly, while the dirtinefs of the perfons employed renders them more difpofed to receive the infection of fever. This cuftom fhould, if poffible, be difcontinued. The other circumftances might be eafily regulated by the overfeers, who would perhaps be induced to pay more attention to them, if premiums were held out, to overfeers who preferved a given degree of health among the perfons under their care. The remonftrance of fo refpectable a body as a Committee of this nature, may alfo be expected to have a proper influence, when they call the atten- tion of the proprietors of manufactories, to practices evidently deftructive of health and life. The great difference in the healthinefs of different cotton mills, which it would be invidious to point out here, but which mvy may be eafily learnt from the lifts of home-patients kept at the Infirmary, for the laft five years, fufficiently proves the benefits of care MANCHESTER MERCURY. 231 reflecting the circumftances I have mentioned, and the danger of inattention. The readmiffion of convalefcents into manufacto- ries, while they are in a ftate capable of infecting others, is an obvious caufe of increaiing and perpe- tuating fevers. To prevent this, it would be proper to retain patients in the fever-wards, till their clothes and perfons fhould be fufficiently purified, and to caution the overfeers of manufactories againft the re- ception of irregular patients, who might return to their employment without leave from their phyfi- cian. A fimilar hazard, which arifes from incautious vi- fits to the fick, may be moft effectually counteracted by regulations in the fever-wards, it would be cru- elty to refufe accefs to near relations, in dangerous cafes; but they might be taught to leffen the danger of receiving infection", by placing themfelves between the patient's bed and the window—by averting the face while the patient fpeaks—and by carefully avoid- ing to fit down upon the bed. All linen belonging to the patients fliould be waffl- ed in the fever-wards, for the fame reafon. I have the honor to be, Gentlemen, Your very obedient Servant, j. FERRIAR. H h 2j2 OBSERVATIONS. J PREVENTION and SUPPRESSION of FEVER. Extrads of a letter from Dr. Haygarth, of Chefler, io Dr. Percival, dated January 6tht*iyg6. " You may remember that in the Chefler Infir- , mary, we have, for the laft twelve years, received all J infectious fever patients that require our affiftance, 1 into the Fever-wards, one for each fex, appropriated 1 to this purpofe.—During this period, it never was i fjsfeded, that infection has been communicated to a \ fingle patient in other parts of the houfe..—In the fl prefent war, Chefler has been unufually expofed to I the danger of infectious putrid Fevers. Many new I raifed regiments, coming from Ireland, with nu- merous recruits taken out of jails, remained in Chefler for a few weeks after their voyage. Great numbers of thefe foldiers and their women were ill of putrid fevers, and were immediately received into the Fever wards of our Infirmary. If fuch contagious patients had been diftributed in the fmall ale-houfes and poor lodging-houfes through the city, the confe- ouences to many of our inhabitants muft have been dreadful. By taking out of a houfe the firft perfon who fick- ens of a Fever, we preferve the reft of the family from infection, together with indefinite number of their neighbors, who would otherwife catch the in- fection. At this very time, when the inhabitants of Mauchefter and many other places, are afflicted with a fatal contagious Epidemic, only two patients are now in our Fever-wards, and both convalefcent: And the Apothecary to the Infirmary, who attends the Out-poor of the whole city, informs me that he -1 has now not a fingle fever patient under his care. Sometimes, but very feldom, our two Fever-wards CONCLUDING OBSERVATIONS. 233 have been fomewhat crowded with patients. I fhould judge that about four, or fix fpacious Wards might be fufficient for Manchefter, though the inhabitants are much more numerous, and perhaps more liable to fevers from their unhealthy dwellings, occu- pations, &c.—I am confident that our two Fever wards do ten times more real good in the prevention of mifery, than all the other parts of the Infirmary. CONCLUDING OBSERVATIONS. From the preceding papers, in union with other accounts of the Yellow Fever, already public, it ap- pears that the following points are well eftablifned. I. That the Yellow Fever, fo called, is only the moft malignant degree of ordinary bilious fever. II. That this Fever may be, and often is generated in the United States, efpecially in the more filthy parts of populous towns. III. That it is not ordinarily infectious, that is, at- tended with fpecific contagion ; but may be render- ed fo, by peculiar circumftances, that confpire to in- creafe its malignancy. It feems to be proved that in New-Haven, the difeafe was introduced and propagated by infection. In Philadelphia, it is admitted to have been, to a confiderable degree, contagious. In New-York and Norfolk, it is equally clear, the difeafe was not intro- duced nor generally propagated by infection. Our beft accounts from Baltimore ftate, that the difeafe there was not infectious. 234 CONCLUDING'OBSERVATIONS. IV. It is demonftrated, beyond all controverfy, that bilious fevers are ordinarily produced by the im- pure air generated by the putrefaction of vegetable and animal fubftances. To this effect there muft concur the following caufes—vegetable or animal matter, heat and water. Heat and water acting on vegetables, or heat alone on animal matter. With- draw any one of thefe cauies, and the effects ceafe. Hence, this important leffon is deducible. High and dry fituations, in the country, and re- mote from ftagnant water, fhould be feleded for healthinefs—and fimilar pofitions for cities; but with this additional caution—to keep them clean. The people of a city make filth enough every week, to generate peftilence, in the hot feafon, and it will pro- duce ficknefs, more or lefs every feafon, unlefs the ftreets and yards are conftantly, not only fwept, but wafljed. Wafhing the ftreets and back-yards fliould be as much a bufinefs of police from June to No- vember, as lighting lamps or regulating weights and meafures. It fliould alfo be an object of police to calculate the mode of paving and draining ftreets, for cleanlinefs, and to direct individuals to do the fame on their back yards. A vigilant police will infpect every article of building, and fee that no sources of pefiriler.ee and death are lurking behind houfes and ftores. V. Another important conclufion refults from the facts ftated ; this is, that country people have not the fmalleft reafon for alarm, on account of the fpreati- m«- of the Yellow Fever. It is indeed certain that people from the country, during the exiftence of this fever in town, are more expofed (if they vifi: the town and breathe the air of it) than the inhabitants. But it h demonftrated by experience that thi* fever CONCLUDING- OBSERVATIONS. 235 ..ill not fpre? i in a pure air. It did not fpread even in New-York, oar the weftern and well-ventilated part of the city. Hei.-ce when the fick remove from town into the country ,or when citizens are taken ill with the fever, after ler.v.ng the city, the people in the country have no oeo;fiou to avoid the fick, or neglect to ad- mi nifter to '.'... .1 all poi :blc comfort and relief; for there is little danger of taking it in a free wholefome air. Place the ';<>:. in v pen airy room and keep it clean, 2:11 •±•: attendiats are in little danger of re- ceiving it. It ; panic that feized the whole continent, when the d -rt'e ap aircu in Philadelphia, is now found to have )eer needier anl w! aoutjut caufe; and it is prefuiu it that luch inhuman caution and barbarous mc/urc-: as were adopted on that occafion, will ne- ver avi.i:. diigracc cur country. Inftead of fhutting d-j^r;; againft the fiving citizens., let every one open his houle and give them an hcfpitable reception. VI. The laft remark on this occafion is that though the immediate cau.es of epidemics may be well un- derftood in moft caies; yet there appears to be a ne- ceffity, in other cafes, to re:ort to a general predif- pofing influence in the atmolphere. Sometimes it happens that very malignant difeafes will not fpread in a country, even when introduced ■from abroad. At other times, a fmall fpark will en- kindle a flame that cannot be refifted. In one year, the putrid fore throat fpreads its ra- vages in one town—the next year, in a bordering town. This year the dyfentery attacks one town, or perhaps a fingle ftreet, with fatal malignity—the next that town is free from it, and the adjacent town % 236 CONCLUDING OBSERVATIONS. is attacked. Thefe facts are within every man's re- mark. But there has been for 6 or 7 years paft, an ex- traordinary run (to ufe a vulgar phrafe) of malignant difeafes and epidemics. The Influenza, in the fum- mer of 1789, firft made its appearance at the fouth- ward. It travelled regularly northward, and reached Bofton the firft week in November. The next fpring, T it began in our frontier fettlements, in March, and travelling fouthward, reached the Atlantic towns in May. Of this fact, I was a witnefs. The fcarlet fever fucceeded. It appeared in 1789, cr '90, in the ftate of New-York, and has paffed ' flowly through the eaflern flates, reaching Bofton j and Portfmouth the laft year, and it has not yet dis- appeared in that quarter. . To thefe fucceeded the Yellow Fever, in various places, which has alfo had its run. During the autumnal feafons, a few years paft, dy- ' fenteries have alio proved uncommonly mortal, in various parts of the country. During the fame feafons, the Yellow Fever has ' been uuufually frequent and fatal, on the coaft of j Africa, and in the Weft-Indies. 1 To what caufe fhall we attribute this general pre- valence of malignant difeafes in various quarters of the globe, at the°famc time ? Specific contagion can- not be the caufe; it will not even account for the rapid progrefs of the Influenza in Europe, and in thb country, for whole to was were feized with it in a day. The Scarletina Anginofa is highly infectious , but it v..;.:- r.ot propagated generally nor principally by CONCLUDING OBSERVATIONS. 237 ; infection. On the other hand, children were feized with it in various parts of the country, remote from the difeafed, and without having the leaft connection with them. Nay more, I can witnefs that when the difeafe was fatal to multitudes in New-York in 1791, and the year before in its worft forms in Connecticut, the fame difeafe, with flighter fymptoms, was even epi- : demic in Hartford. The mild form in which it ap- peared, feemed to be but a prelude to the difeafe which in the two fucceeding years proved fo fatal. I was witnefs to it, in this mild form in my own family: , a fevere catarrhal affection, accompanied with high fever, and a partial efflorefcence of the fkin about the throat and breaft. L . -This fact would feem to prove, not only a general predifpofing caufe in the atmofphere, but a progrefifive Jlate of that caufei' , Another fact would feem to juftify this remark. It is well known that foreigners, coming from other cli- mates, are very eafily affected with the difeafes pre- . valent at the time of their arrival, and more eafily take fuch diforders than natives.—Now it is a fact 'within my obfervation, that foreigners arriving [froni Europe at New-York in 1794, were feized I'wiih the . fcarlet fever, after it had ceafed to (affect native'citizens. The refult of this obferva- tion is, that the decreafe of the predifpofing influence of the atmofphere, is progrefifive, and that it was fuffi- cient to affect foreigners, for fome time, after it ceafed to affect perfons accuftomed to breathe the air of our I climate. 238 CONCLUDING OBSERVATIONS. Indeed fomething of the fame kind is true, with refpect to the Yellow Fever, in New-YorK. The fame difeafe had appeared, in a few inftances, for two or three feafons preceding the year 1795. Several cafes occurred in 1794. Thefe cafes itemed to L»e harbingers of the more general mortality of the laft feafon. I do not know that this difeafe appeared in Phila- delphia, in the laft feafon preceding the fatal autumn of 1793 ; but feveral cafes have occured the two laft years. A friend of mine who loft two clerks in the fatal feafon of 1793, loft two others in 1794, and one in 1795 ; all from the fame counting houfe. In thefe cafes, there is no pretence of infection.— The difeafe muft have fprung from local caufes, or the predifpofing influence of the air inhaled by thefe unfortunate people. I am therefore inclined to believe that independent of local caufes, the atmofphere may be and is often affected by fome general invifible caufes, which, at particular feafons, difpofe the human body to parti- cular difeafes. Whether this difpofition in the air proceeds from the prevalence of particular winds— of rains—of heat—or of froft ; or whether the af- pects of the planets, or the various action of that all- powerful elementary fluid, electric fire, which feems to be the-moft energetic principle in the fyftem, may not vary the combination of fubftances compofing vital air, are queftions for the inveftigation of the philofopher. The facts which are within common obfervation are fufficient to point to the proximate caufes of difeafe, and that when thefe are^ known, moft of the evils of ficknefs, are brought within the influence of human management—many of them may be obviated—all of them, mitigated. CONCLUDING OBSERVATIONS. 239 If it is clearly afcertained, that the gas generated by the decompofition of animal and vegetable fub- ftances, in putrefadion, is fatal to healthy life ; then it becomes a duty to depofit fuch fubftances in places where they cannot annoy us. It is as much the duty of the citizens of populous towns, to cleanfe their ftreets, and their back yards, wafh their houfes and bathe their perfons, as it is to provide a Hofpital tor the indigent fick, or a grave for the dead. Thus in the country, people fhould choofe dry frtuations for their houfes, remote from marfhy grounds. They fhould particularly guard againft the noxious effeas of the heat on land juft drained of water. While land is covered with water, even if flagnant, no very pernicious effects are to be appre- hended ; but terrible are the effects of a hot fun on the putrid fubftances that line the bottoms of ponds, when they are fuddenly expofed, by the draining off of the water. Thus,alfo,fettlers on new lands are toguard againft the firft effeas of clearing moift land. While veget- nble fubftances are covered with water, they are harmlefs; and while marfhy grounds are fnaded by thick forefts, they produce no difeafe. The heat is not fufficient in the deep fhade of a foreft, to extri- cate the noxious Gas*. But on opening thofe mar- fhy grounds to the aaion of the fun, all the latent feeds of difeafe are fet in motion and impregnate the furrounding atmofphere. Then the inhabitants be- come fickly, and continue, more or lefs?< to be fo in hot weather, till the furface of the earth is effeaually dried or cleanfed by ploughing and cultivation. I i T It is faid that a degree of heat equal to 8o° by Farenhelt's fcale, is neceffary to extricate the deleterious gas from vegetable fubftances—^ degree never felt i» the recefles of 3 fhady foreft. 2r0 ADDITIONAL REMARKS. [J ADDITIONAL REMARKS. Since the preceding obfervations were compofed, ihe Editor has received the following remarks, from a friend, with liberty to make them public. And as they appear to him of fufficient importance to juitify an infertion in this place, he prefumes no apology is neccfiary for fo doing ; although they are, in part, a repetition of his own. A fubjea fo important to the welfare of the citizens of the United States, can hardiv be exhibited in too many points of view. The means of prevention, not only of Yellow Fe- vers, but of all other fevers, in any degree of the fame nature, are principally two : and this is equally true in refpea to individuals and communities. Thefe two means are temperance and cleanliness. I. Temperance. No truth is more certain, or more eafily demonftrable by numerous and important {act?, than that different climates require different modes of living. It is from inattention to this Am- ple truth that a large fliarc of all the phyfical evfts of men arife.—Thus, many kinds of food and various liquors, are harmlefs, and even neceffary in cold countries, which are abfolutely pernicious in hot cli- mates. Thus, exercife in the open air, is highly ad- vantageous and healthful, at all hours in the day, in temperate regions; while in many parts of the world, beneath the torrid zone more efpecially, an expofure to the fogs of the morning, the heats of the noon- tide, or the dews of the night, are certainly deftruc- tive.—Confiderations of this nature„,are very little ;bought of, and ftill lefs attended to, among people at ADDITIONAL REMARKS. 24 : large : and indeed .the mafs of population, in the greater part of the earth, are incapable of appreciat- ing the confequences of the obfervance or neglect.— In all their changes of place, they carry with them the fame cuftoms ; v and it is by long experience only that they are taught the neceffity of adapting their habits to their new fituations. By far the largeft portion of the United States lau been peopled by emigrants from the northern coun- tries of Europe. Wherever they have fettled they have continued, with very trifling deviations, to-pur- fue their accuftomed occupations and modes of living. Meats and ftimulating liquors are more ufed in north- ern climates, than in fouthern, and with lefs diiacr- vantage. Our anceftors continued to confume them after their fettlement in this country, in the fame manner as before ; the confequences have been un- fortunate ; of late, by conneaion with other circumftan- ces, they have become ftill more deftructive, and we are beginning to be alarmed.—A numerous train of faas ; the example of almoft all Afia, Africa, and the fouth of Europe ; demonfhate the advantages of tem- perance, both in foods and drinks, and the fatal effefts of adeparture therefrom. Rice,and other grains, fruits, and water, form nearly the fole articles of confumption, among the inhabitants of thefe countries, during the fultry feafon. It is only on their fea-coafts, where commerce has colkaed foreigners from all part.;, and efpecially from Europe, and where every fp-cies of riot and intemperance is common, that the neiii- lential Fevers, of which we hear fo much, prevail.— In the fouth of Europe, in Italy, for inftance, even in the maritime cities, where the people either from neceffity cr choice, abftain from meats, wines and 24^ ADDITIONAL REMARKS. other intoxicating liquors, during great part of the year, general and peftilential difeafes rarely appear: particularly, among thofe nations who are attentive to cleanlinefs. The city of Naples contains about four hundred thoufand inhabitants ; of whom thirty or forty thou- fand are faid to belong to the clafs of beggars.—In that climate the rains prevail, with little intermiffion, for three months—from February to May. From May to September, a drouth, equally fevere, and fcarcely allayed, in many years, by a fingle plentiful rain, renders the heat almoft intolerable. The wages of a laborer not exceeding eight pence this currency, a day, and meat being rarely had in their markets for lefs than four pence the pound, and vinous li- quors in the fame proportion,—the mafs of popula- tion is excluded from any fhare of thefe luxuries ; of confcquence they fupport themfelves on vegetables,' roots, fallads, fruits, &c.—and dilute their food, and animate their fpirits, with water and lemonade.— Yet this city has, for a great number of years, known no general difeafe. And for ten years, no febrile difeafe, of any fort-, was common among them.— They, alio, pay great attention to perfonal cleanlinefs. Facts of this fort are very important, and form the belt comment on the difcordant opinions of our phyfi- ciau-a II. Cleanliness. It is fo the rigid obfefvance which the eaflern nations pay to ablution, that, in connection with their habitual temperance, we are to afcribe their fuperior health and longevity ; and to the neglea of the inhabitants of the fouthern parts of America, in refpect of both thefe particulars;, their ADDITIONAL REMARKS. 243 ficknefs and mortality.—It is impoffible to prefs this matter too forcibly upon nations, communities, fami- lies, and individuals. All are concerned in it.—The people of the United States, as a people, are noted for houfehold cleanlinefs. They are far below the Dutch in refpea to the falubrity and purity of their towns; and below the French, Italians, and even Swedes and Ruffians, in regard to perfonal cleanlinefs. In many parts of Italy, public baths are more nu- merous than coffee-houfes and taverns. In France, machines and utenfils for bathing, form an effential part of the houfehold furniture of every well-regu- lated family ; and a woman would as foon think of going into company, with unwafhed hands and un- combed hair, as without having made ufe of the bath. In Sweden and Ruffia, the pooreft and moft abjea of both fexes, would hold themfelves unworthy to appear before the Deity in his temple, on the Sab- bath, if they had not devoted fome part of the pre- ceding day to perfonal ablution. This is not the cafe in England ; and the confequences of thefe national cuftoms may be traced in the hiftory of our own country. Who does not recollea the mortality which prevailed among the early Englifh colonifts in Virginia ? Who has not read, or heard, of the long ' fevers, as they were called, of the New-England flates f—But did ever any perfon learn that thefe mif- fortunes.afHiaed Pennfylvania and New-Jerfey while they were called New-Sweden ?—Philadelphia and the neighboring parts of New-Jerfey, were originally fettled by Swedes. Thefe people were neither more rebuff, nor more circumfpea, in the generality of things, than the Englifh fettlers ; but they brought with them their habits of perfonal cleanlinefs, and 244 ADDITIONAL REMARKS. they were rarely vifited by difeafes.—Even fo late as when Profeffor Kalm vifited this country, the prac- tice of univerfal weekly bathing, was ftill preferved, among the remnant of the Swedifh inhabitants. In former ages, and among the celebrated nations of antiquity, perfonal, as well as general cleanlinefs, was confecrated by numerous rites, and incorporated into every religion. Among a barbarous and igno- norant people, this was, perhaps, the only means of fecuring a proper obfervance of this duty. It were fortunate for the United States if the old difpenfa- tion were revived, in this particular. The laws of Mofes, in relation to the virtue of cleanlinefs, bear imprefied on their front, the charaaers of a wifdom nothing fhort of divine.—The days of prophets and of miracles are paft ; but finely, in a matter of fuch effential importance to the well-being of our country, the care of leghiation fhould be extended to fupply the neglea of the moralift. Thofe rulers but par- tially confult the durable felicity of the people they govern, who through ignorance, indolence, or a fpirit of pariimony, mifcalled economy, overlook, or fail to remedy, a defect fo interefting to private and public happinefs, to individual and general tranquility and virtue. In addition to the preceding obfervations, one re- mark further may be addreffed to the people of the United States, generally, but more particularly to the fettlers on the new lands.—Great and fudden altera- tions in the face of a country, rarely fail of being fol-* lowed by changes in the ftate of the inhabitant of ADDITIONAL REMARKS. 245 that country, proportionably rapid and confiderable. The opening of new land and water communications, the draining of marfhes and deftruaion of forefts, have a moft extenfive, and often unfortunate influ- ence, for a time, on the country in which they take place. As one of the fureft means of preventing bad confequences, the attention of the people engaged in undertakings of this kind, fhould be turned to the inducing as rapid and luxuriant a vegetation, on all fuch clearings up, as poffible. It behoves them, 'ike wife, to-pay a double regard to the duties of *«^er, temperance, and cleanlinefs. The moft fatal effeas fbttvar from ntslea in thefe particulars; and efpecially from that free