■■ ••■Mm'AX ■• ,:.'■ ■ '■ ' ::,:.:;iijn 1 ::':!'' ."iitJiNivjIli."!!!!] 1 itii'- UNITED STATES * MI OF AMERICA Wo •^ * * FOUNDED HSEf to 1836 WASHINGTON, D. C. OPO 16—67244-1 A BRIEF HISTORY O F EPIDEMIC and PESTILENTIAL DISEASES j WITH THJE PRINCIPAL PHENOMENA OF THE PHYSICAL WORLD, WHICH PRECEDE AND AC- COMPANY THEM, AND OBSERVATIONS DEDUCED FROM THE FACTS STATED. IN TWO V.OL UMES. By NOAH WEBSTER, Author af Differtations oa the gngli'fli Language and feveral other Works—Member of the Connecticut Academy of Arts andSeiences —of the Society for the Promotion of Agriculture, Arts and Man- ufactures, in the State of New-York—of the American Academy of Arts and Sciences, and correfponding Member of the Histori- cal Society in Mafiachufetts. ,4 _____—==__ - - _i*L _ - v_ VOL. I. v yj ( S y HARTFORD: PRINTED BY HUDSON fc* GOODWIN. 1799. [PUBUSBED ACCORDING TO ACT OF CONGRESS."] ADVERTISEMENT. THE work quoted, under the title of " Magdeburgh Jiiftory," is a compilation of Ecclefiaflical Hiflory made by feveral writers at Magdeburgh, and divided into centuries. The work quoted under the title of " Hid. Augufh" is a colleftion of the hiftories of the Roman affairs under the Em- perors. The work cited under the title of " Angl. Script," is a col- lection of the early hiflorians of England. The work cited under the title of " Germ. Script," is a col- lection of the ancient hiflories of Germany, by Piflorius. In a few infknees, authors are cited without the page or chap- ter. This has arifen from the manner in which my materials were obtained—which was to tranferibe pafTages from books wherever I found them, in public or private libraries, and fome- times, when books fell in my way by accident, without the in- tention of ufing them as authorities. The inftances however are not numerous, and the paflages may generally be found with eafe by the index or chronological order of the work. Since I have had it in view to publifh this treatife, and tfpecially fince difcov- ering a difpofition in fome perfons to decry this attempt to in- veftigate truth, by charging me with a defign to collect facts for the purpofe of fupporting preconceived opinions, I have been more careful to note my authorities. This muft be my apology for citing fo many authorities, which might otherwife appear like affectation. CONTENTS of the FIRST VOLUME* Introduction, . . . . Page*. SECTION I. Of the divcrflty of opinions refpeaing the caufe and origin ofpef- tilence. .-------9. SECTION IT. ffiflorical view of peflilentlal epidemics, and the phenomena in the pkyfical world which precede, attend or follow them, from the earlitfl accounts to the Chrlflian era, ... 24- SECTION III. Hiftohcal view of peflilentlal epidemics, from the Chriflian era, to the year 1347, -.---- 65. SECTION IV. i Hiftorical view of peflilentlal epidemics, from the year 1347 ti 1500,.......I33« SECTION V. Hiftorical view of peflilentlal epidemics from the year 1500/0 1600. BI- SECTION VI. Hiftorical view of peflilentlal epidemics from the year 1600 to the clofe of the year 1700, - - - - I71* SECTION VII. Hiftorical view of peflilentlal epidemics from the year 1701, to the year 1788,......216. SECTION VIII. Hiftorical view of peflilentlal epidemics from the year 1788 to the year 1799, including the lafl epidemic period, - 283. ERRORS, Page 37, line 9, from bottom, read ftccitare. 44, line 10, read metu. 76, line 16, read Lampridius. 87, line 3, from bottom, after cold, place a comma. 104, line 22, read deacon. 106, line 2, read inguinaria. 156, line 9, read Alcmar; alfo in page 174, line 1%. 169, line 4, from bettom, read Penrith. 204, line 18, after petechial, read fever. 241, line 3, read 1750. 260, line 18, for of read or. IN page 255 a fact is dated which contradicts the ftatement reflect- ing the planet Mars in page 241. There 13 an error in one of the ftatements; and I leave aftronomers to determin by calculations which of the authorities, Ames' Almanac for 1750, or the Annual Regifter, is wrong. The error is not material to my fubject. The only queftion of confequence, is, whether the near approach of Mars had any influ- ence, in producing the extreme heat of 1749 and 1766—a queftion I pretend* not to determin. INTRODUCTION. xV PUBLICATION on the fubjeft of difeafes, from the pen of a man who has never before turn- ed his attention to medical fcience or to chymiftryj is a circumftance, which, if it does not require an apology, demands at leaft an explanation. The prevalence of the catarrh, commonly called influenza, in the years 1789 and 90, firft awakened my curiofity on the fubjecT: of epidemic difeafes. A journey which I made in October 1789, from Hartford to Bofton ; and another in March 1790 from Hartford to Albany ; led me to obferve the progrejfvvenefs of that difeafe, with its other phe- nomena. The appearance of the fcarlatina anginofa in 1793 revived my curiofity, and a fimilar circum- ftance, a journey from Hartford to New-York in April of that year, led me to obferve a progreflion in that difeafe from Weft to Eaft. A flight attack which my own children fuffered, in May following, together with a fimilar attack of many other chil- dren in Hartford, and its more violent effects fome months after, convinced me that the epidemic was prognffive m malignancy, as well as in regard to place. Had no other epidemic appeared, my curiofity would probably have fubfided and been extin- guifhed. The malignant fever in New-York in j 791, had excited alarm in that city, and was a a VI fubjedt of notice in Hartford where I then refided 5 but no idea had been conceived, that it was con- nected with a peftilential ftate of the air,* in the United States, which was afterwards to produce more ferious and general calamities. In autumn 1793 however that peftilential flate of air arrived to its crifis in Philadelphia, where the mortality occafioned by the yellow fever, fprea<| deitruction and difmay, from Auguft to Novem- ber. ' The fatality of the difeafe fpread confterna- tion thro the United States, and excited apprehen- fions in Europe. Nw American citizen could be indifferent to the prevalence of this difeafe in his own country. Still it was conceived that the diftemper might have been produced from imported infection, and that a more rigid execution of the laws relating to quarantine, might prevent a repetition of the calamity. Here refted apprehenfion and enquiry. But this tranquillity was of fhort duration. The appearance of the fame difeafe in New-Haven in 1794, and in New-York, Baltimore and Norfolk in 1795, revived my curiofity, with double zeal to fearch out the caufes of thefe phenomena, fo unuiual in this country. The facts which had come to my knowledge, relating to the origin and prop- agation of this difeafe, led me to fufpect the com- mon theory of inftclion to be ill-founded. But as a preliminary to all other enquiries, it appeared neceflary to fettle the controverty relative to the imported or domejlic fources of the diftemper; for without a decifion of this queftion, legiflarive and police-regulation*, for preventing a return of the evil, or mitigating its feverity, would probably be fruitlefs. The queftion appeared to be extremely important, and the differences of opinion on the fubject, among medical gentlemen, feemed to pre- clude the poflibility of a decifion among them,% that mould filence doubts in the public mind. In this fituation of thecontroverfy, I refolved to make an effort to obtain evidence which miaht de- cide the point, in one way or the other ; and as facts only can be relied on as a fure bafis of prin- ciples and theory, I determined to make a collect- ion of facts, from all parts of the United States, where the yellow fever, or other malignant fevers had prevailed, during the preceding years. For this purpofe, on the 31ft of October 1795, I ad*. dreffed a circular letter to the phyficians of Phila- delphia, New-York, Baltimore",'Norfolk,- New-Ha- ven, and in genera!, throughout the United States, requeuing them to communicate to me whatever facts bad come within their obferv'ation, which could throw light on the queftion of the foreign or domeftic. origin of the yellow fever. In confe- rence of which I received a number of commu- nications, which were publifhed in 1796, and to which is prefixed my circular letter. Thefe communications, tho lefs numerous and Satisfactory than were defirable, united with a mul- titude of fads within my own obfervation, convin» ced me of the fallacy of the vulgar opinion, re- fpecting the origin of the yellow fever in the Uni- ted States, from imported fources. I found re- peatedly that the reports of perfons taken ill, in confequence of intercourfe with veflels from the viii Weft-Indies, or with difeafed feamen, infected cot- ton or clothing, or the like caufes, were mere idle tales, raifed by the ignorant or interefted, and wholly unfupported by evidence. Scarcely an in- ftance could be found, in which the evidence of the propagation of difeafe, from, imported infection, was fuflicient to render the fact even probable. On the other hand, the evidence of the origina- tion of the difeafe in New-York, Baliimore, Nor- folk, Newburyport, Bofton and Charlefton, appear- ed to be clear and fatisfactory. In moft of thofe places, the fact has never been queftioned. When the fame difeafe appeared in Philadelphia.» in 1797 ; the queftion of importation or domeftic origin, again agitated the faculty and the public The revival of the difcuflion, and particularly, cer- tain publications of Dr. William Currie, in the Philadelphia prints, called forth my exertions to unite opinions and fave the citizens of this country from the detraction of meafures, which muft ne- ceffarily follow a divifion of opinions. I confidered and ftill confider the queftion as refting principally on fact, and not on medical fkill; therefore proper to be inveftigated and difcufled by any man who has leifure and means, as well as by phyficians. Thefe confiderations gave rife to the obferv>ations which I addreffed to Dr. Currie, thro the medium of fhe public papers, in the months of October, November and December 1797. The defign of thefe obfervations was originally limited tothepur- pofe of proving the yellow fever of our country to be generated by local and domeftic caufes, by lay- ing together the fads which I had colle&ed from IX various parts of the United States, without any in- tention of examining the hiftory and phenomena, of peftilential difeafes in other countries, and other periods of the world. In purfuing this objed however, I was led infen- fibly to examin all the books I could find, on the fubjed of the plague j and the fubjed being new, I found too much pleafure in profecuting it, readily to abandon the purfuit. Fads which were new to me were daily prefenting themfelves to my mind ; and after three months inveftigation, I was perfua- ded that thofe fads are of too much importance to philofophy, to medicin and to human happinefs, not to merit publication. Such is the origin of the prefent treatife. When I began my enquiries into the origin of the yellow fever, in 1795, I had no preconceived fyftem to maintain. My view was to colled fads and from them to deduce truth. It is not my intention to advance theory over fad ; but as far as juft philofophy and found logic will permit, draw theory from fads, and if poflible, by fair reafoning, from the uniform operations of nature, to arrive at fixed principles. If conjedures fhould in any inftance be advanced, they will be offered as fuch, and not as the bafts of pradice. As there is a difference of opinion in regard to the caufes of the plague, and other peftilential dif- eafes, as well as in regard to the identity of the yellow fever and plague, I fhall define my manner of ufing certain terms, which will often occur in the following work. Jf That peftilential difeafe which ufually, in the Levant, produces fwelling^ in the glands, as buboes, I mall call the glandular or inguinal plague. The peftilential difeafe which has afflided fome of the cities in America, and is ufually called yellow fever, I fhall denominate, the bilious or American plague. In the Levant plague, fwellings in the groin, in the arm-pits, and behind the ears, do not, in every cafe, appear ; but they are the general diltinguifh- ing marks of the true peftis or plague. In the yellow fever, the fkin is not, in every cafe, marked by a yellow color ; but it l> generally the fad, and therefore this form of peftilencTe may very well take its denomination from that circum* ftance of its bilious appearance. Whether thefe are difeafe fpecifically diftind, or only the fame difeafe varied and modified by cli- mate, feafon or other circumftances, is a queftion that belongs to the faculty. It is fufEcient for my purpofe to obferve, that in moft of the fymptoms, they agree—that they are peftilential and greatly to be dreaded by mankind. I fhall therefore treat them as different forms of the fame difeafe. There may be fome caufe for believing that the moifture of a country, abounding with woods, and marfhy grounds, may occafion the difference in the color of bodies which fall vidims to peftilence. The words infection and contagion, are ufed by medical writers and in popular cuftom, as fynony- mous, and their etymologies warrant the pradice. But I conceive there are diftindions in this quality or power of difeafes, of communicating themfelves XI by contad or near approach, which require to have each its appropiiate language. That quality of a difeafe which communicates it from a lick to a well perfon, on fimply inhaling the breath or effluvia from the perfon of the difeafed, at any time and in any place, may be called fpecific contagion. Such is the contagion of the fmall-pox and the meafles, which are therefore called conta- gious difeafes. That quality of a difeafe which, tho infalutary will not communicate it, without the aid of other caufes, as v/arm weather, or peculiar fituation and ' habit of body, and which requires the healthful perfon to be a confiderable time, under its influence, to give it effed, may be called inftclion. Such is the quality of the plague, in all its forms, dyfen- tery, and all typhus fevers. It may perhaps be poflible for the effluvia of thofe who have thefe dif- eafes, to be fo concentrated and virulent, as to communicate them to a perfon in health, by a fin- gle infpiratibn of air into the lungs. But if fuch can be the cafe in any inftance, it is not the ordi- nary ftate of thofe difeafes. Even in the plague, many attendants on the fick never receive the difeafe at all ; and in mod cafes, healthful perfons may, for hours, breathe the air of the rooms where the patients are, without any injury. Hence infedion is capable of all degrees of ac- tivity and force, from a flight impurity of air, which affeds no .perfon in health, to that virulent ftate of air, which will produce vomiting in a per- fon fuddenly expofed to it. Infeclion is ufually ren- dered inadiye by fevere cold j fpecific contagion is Xll never deftroyed, but often rendered more adive by cold. Hence the winter in northern latitudes ufu- ally puts an end to the plague, but makes no fa- vorable alteration in the fmall-pox. There are fome exceptions to this remark, as it regards the plague, which will be noticed in the following work. Thefe diftindions, which will appear, in the courfe of this treatife to be well founded, have never been defined or ufed by European phyficians, fo far as my information extends ; and to the want of them, are to be afcribed many errors and abfurdi- ties in opinion, as well as warm controverfies in re- gard to the contagion of the plague. That ftate of our atmofphere which produces difeafe, or difpofes the body to difeafe, independ- ent of other caufes, I call general or primary conta- gion. Synonymous with thefe phrafes, will be ufed a peftilential ftate or conftitution of the air. The word pejiilence may be ufed as fynonymous with plague; or as exprefling all kinds of conta- gious and infedious epidemics. I have ufed it in both fenfes ; and often to exprefs an idea of that feries of epidemics which are clofely conneded with the plague. Whether thefe diftindions are juft or not, is not very material; it is fufHcient that they will exprefs my ideas in the following treatife. SECTION I. Of the dlverfity of opinions refpealng the caufe and origin of . peflilence. T ROM the date of the earlieft hiftorical records, the opin- ions of men have been divided on the fubjedt of the caufes and origin of peftilential difeafes. All enquiries of the philofopher and the phyfician have hitherto been baffled, and inveftigations, often repeated, have ended without leading to fatisfadtory con- clufjons. In the hiftory of opinions on this myfterious fubjecT:, there is a remarkable diftinclion between the ancients and moderns. The ancients derived moft of their knowledge and fcience from perfonal obfervation, as they had very few books and little aid from the improvements of their predecefTors. The philofo- phers of antiquity, attentive to changes in the feafons and to the revolutions of the heavenly bodies, attempted to trace pefti- lential difeafes to extraordinary viciflitudes in the weather, and to the afpecls of the planets. Modern philofophers and phyfi- cians, on the other hand, unable-to account for peflilence on the principle of extraordiaary feafons, and difdaining to admit the influence of the planets to be the caufe, have reforted to in- vifible animalculae, and to infection concealed in bales of goods or old clothes, tranfported from Egypt or Conftantinople, and let loofe, at certain periods, to fcourge mankind and defolate the earth. < In both periods of the world, the common mafs of people, ufually ignorant and always inclined to believe in the marvellous, B IO have cut the Gordian knot of difficulty, by afcribing peflilence to the immediate exercife of divine power; under the irapref- fion that the plague is one of the judgments which God, in his wrath, infli&s on mankind to punifh them for their iniquities. Without deciding on the comparative merit of thefe refpe<5r- ive opinions, it is fufficient to obferve, that they are all probably incorrect; and thofe of the philofophets, altogether inadequate to explain the origin of peftilential Epidemics. It may however be of ufe to infert, in this place, the expla- nations of the caufe of peflilence, given by fome of the princi- pal writers on the fubjecT. Hippocrates, the father of medical fcience, and a man of very acute obfervation, confidered peflilence as the effect of partic- ular feafons and winds. A peftilential ftate or conftitution of air he defcribes, as occafioned by a continuation of foutherly winds, and a warm, humid, clouded atmofphere. De raorbis vulgaribus, lib. 3. Galen followed the fame theory. He fays that peftilent dif- eafes arife from a putridity of the air ; and in another place, a call flatu, from the ftate of the air or weather. p. 627, in Hippoc— It will at once occur to an intelligent reader, that a particular defcription of weather, producing peftilence, muft be principal- ly calculated for a particular country or latitude. The ftate of feafons which Hippocrates calls peflilential, is evidently calcula- ted 10 produce or augment autumnal difeafes in temperate lati- tudes ; and is precifely the ftate of weather which exifted in the United States in 1795, when the bilious plague prevailed in the cities of New-York, Baltimore and Norfolk. But it does, not correfpond with the feafon in 1793, when the fame difeafe raged in Philadelphia ; for that was exceflively dry, nor with the mmmer of 1797, which was temperate, in refpec"t to heat, cold ard moifture. Hippocrates indeed feems to have been aware that the feafons alone were not fuflicient to account for peftilence, for he fpeaks of to theion, fome divine principle in the air, by which modern II writers of celebrity fuppofe to be intended what is now called an epidemic confliiutlon, refulting from changes in the atmofphere produced by unknown caufes. Ariftotle prob. i. relates that a hot and dry fouth wind will produce peftilence. The philofophical warrior and Liftorian, Ammianus Marcel- linus, after mentioning a plague which broke out in Amida, a city of Peifia, when befieged by Sapor A. D. 359, from the corruption of numerous dead bodies which lay unburied in the ftreets, proceeds to unfold the caufes of peftilential diftempers, in the following manner. " Philofyphers and eminent phyficians have taught that pefti- lence is produced by excefs of heat or cold, of drouth or moif- ture. Whence it is that thofe who live near wet and marfhy places are fubjefl to coughs, difeafes of the eyes and the like. I Thofe, on the other hand, who refide where the heat is great, are troubled with febrile complaints; and in proportion as the matter of fire is more active, drouth is more rapid in deftroying life. Hence, during the war of ten years in Greece, this fpe- cies. of difeafe prevailed, and it was faid that men perifhed by the weapons of Apollo, by which was fuppofed to be meant, the heat of the fun. And, according to Thucydides, the mortality among the Athenians, in the beginning of the Peloponnefian war, was occafioned by an acute difeafe, which proceeded from the fervid regions of Ethiopia, and gradually extended to Attica. " Others are of opinion that air, like water, vitiated by the effluvia of dead bodies, or fimilar fubftances, is deprived of its falubrity ; or at leaft that a fudden change of air will produce the more flight complaints. Some alfo affirm that the air, ren- dered grofs by a denfer vapor from the earth, doling the pores of the body and checking perfpiration, becomes fatal to the lives of fome ; for which reafon, other animals than man, which are continually bending towards the earth, are the firft victims to peftilence, as Homer teftifies, and which is proved by many examples, during the prevalence of peftilential difeafes. " The firft fpecies of plague is called pandemic, and this af- flicts moft feverely thofe who are fubject to exceflive heat, in hot regions. The fecond is denominated epidemic, which when 12 it rages, obfcures the fight and excites dangerous humors. 'The third Lamodes, which is temporary, but produces fudden death/' Lib. 19. The hiftorian has here explained the caufes of ordinary dif- eafes, occafioned by extremes of weather, marfli effluvia, vitia- ted air, and the direct action of violent heat, or ftroke of the fun. No perfon will difpute the juftnefs of his remarks, for the fame caufes, at this day, produce the fame effects. But the caufes afligned are not adequate to all the effedls, which we wifh to explain. They do not uniformly occafion peftilence ; and on the other hand, peftilence fometimes rages without the influence of thofe caufes. yEtius, an eminent phyfician, about t;he clofe of the 5th cen- tury, compiled the opinions and methods of cure practifed by th.. molt celebrated of his predecefTors. In this compilation, entitled " Tetrabiblos," chap. ix. we find the following para- graph on xhc iubjeit of Epidemic difeafes. " Thofe are called popular or epidemic difeafes, which fpring from a common caufe, as bad food or water, immoderate grief or want of cuftomary exercife, hunger or repletion, efpecially when abundance fucceeds extreme want. But the natlire of the country often caufes epidemic difeafes : the air we breathe being vira-cd by the evaporation from putrid fubftances. Thefe fub- ftances are multitudes of dead bodies after battles, marfhes or ftagnant water in the vicinity, which emit poifonous and fetid vapours.—This caufe is in continual operation. And the air which furrounds us, always changes its temperament, when it becomes immoderately hot or cold, dry or humid. To other caufes we are not all equally expofed, nor at all times ; but the circumambient air, when we are abroad, furrounds us all alike, and is inhaled with the breath. " Sometimes the furrounding air, becoming unufually humid and hot, induces a peftilential conftitution ; and as humors, tending to putrefaction, are collected in the body by eating un- Y/h<>*-_fome food, this air becomes the fource of a peftilential fever. Therefore if a perfon takes moderate exercife, and is '3 temperate and regular in his diet [victu modefto ac caftigato] he wholly efcapes all affections of this kind." Such were the opinions of the phyficians and philofophers of antiquity. No diftinction appears to have been made by them, between the plague and other peftilential difeafes. All were afcribed to the fame caufes. At what time the diftinction between Peftis and Peflilentla was firft made, has not occurred to my enquiries. But I find it in the writings of Profper Alpinus, a Venetian phyfician, who wrote about the clofe of the 16th century, and who had been, for fome years, a practitioner in Egypt. This author maintains that peftilcnt fevers are occafioned by local caufes, as vitiated air, and by peculiarities of feafon, as extreme heat and humid- ity. But he afferts that the plague in Fgypt rarely proceeds from corrupted air, and never, except after an unufual overflow- ing of the -Nile, when that river has exceeded its common bounds. He contends that if this difeafe was produced by noxious exhalations from putrid and ftagnant'water, and marfhy places, it would occur every year. He therefore concludes for certain that the plague is ufually imported from Greece, Syria, Barbary, or Turkey. " Plerumque igitur id genus morbi ibi contagio ex aliis locis afportari folet." The contagion of the plague is ufually imported from other countries. Rerum. Egypt, vol. 2, p. 73, vol. 3, 61, and vol. 4, 299. The fame author alTerts that the plague brought from Barbary is more malignant and of longer duration, than when brought from Greece or Syria. Diemerbroeck, an eminent Dutch phyfician of the laft cen- tury, has recorded an account of a violent plague in Nemueguen in 1636, and fubjoined to it the beft treatife on the origin of that difeafe, which I have been able to find, tho in one or two particulars, his ideas are very inaccurate. This author, whofe treatife, I am furprifed to find, is little known in this country, afligns three caufes of the peftis or true plague. Firft, the jufl anger of heaven, provoked by the exhalations from the finks of our fins and abominable deeds. Secondly, a mo«t malignaat, poifonous, and to human nature, deadly peftilent germ, jTemi. *4 narium,] like a fubtle fermentum or leaven, fent from heaven, in a very fmall quantity, diffufing itfelf through the air like a fubtle gas, and rendering it- impure. This gas, he fuppofes to fpread over many regions its numerous particles, and to imprefs on the air an infection like poifon, which often affects not only many perfons, but almoft the whole world. However whimfical we may think this author's explanation of the peftilent principle ; that fome fuch general caufe exifts in the atmofphere, at certain periods, will be rendered very probable, if not certain, by the facts hereafter to be related. * The " feminarium e coelo demiffum" of Diemerbroeck feems to be the to theion of Hippocrates. In what the efTence of this principle confifts, is not known ; but there muft be an alteration in the chymical properties of the atmofphere to folve the diffi- culties that attend our inquiries into the caufe of peftilence.— That this alteration is the effect of a poifon, " e ccelo demiffum," is an hypothefis unfupported by facts and wholly incredible. The third caufe of peftilence, mentioned by this author, is infection. Diemerbroeck alfo maintains the diftin&ion between peftis and peflllentla. The latter is fuppofed to proceed from foul exhala- tions, intemperate feafons and the like. But the plague, he contends, cannot be occafioned by thofe caufes, tho thefe may aid the feminarium or general caufe. Van Helmont, a Flemifh writer of fome celebrity, in the laft century, maintains that the plague cannot be afcribed to the " importunate and unfeafonable changes of times, nor to pu- trefaction ;" that the " poifon of the plague is a far fecret one from any other;" that the " matter of that difeafe is a wild fpirit tinged with poifon,. exhaling from a difeafed perfon, or drawn inwards from a gas of the earth putrified by continuance, and receiving internally an appropriate ferment, and by degrees attaining a peftilent poifon in us." " The remote, crude and firft occafional matter of the peftilence, is an air putrified thro' continuance, or rather a hoary putrified gas, which putrefaction of the air, hath not the 8200th part of its feminal body." This explanation feems to be hardly iatelligible. Works, Lond. Edit. 1662, p. 1085,1090,1102, 1125. "5 This author contends that " the peft is not fent down from heaven, but that popular plagues do draw their firft occafional matter from an earthquake, and from the confequences of camps and lieges." p. his- Hodges, who wrote a treatife on the great plague in London in 1665, obferves that the air fuffers fome effential alteration which is neceffary to favor the propagation of peftilence. The nitro-aerial principle, which caufes or invigorates vegetable and animal life, fometimes becomes imperfect, degenerate or cor- rupt, being tainted with fomething pernicious to vitality. He calls it poifonous, and obferves that it proves injurious to trees and cattle, as well as to man. He fuppofes the corrupting prin- ciple to be a fubtle aura or vapor extricated from the bowels of the earth. To this caufe alfo he afcribes the death of fifh du- ring periods of peftilence. At the fame time he contends that the infecting principle is generated in Africa or Afia, and con- veyed to other countries. The feat of the difeafe he fuppofes to be in the animal fpirits. Van Swieten maintains that the caufe of Epidemics is in the ■hidden qualities of the air, and inexplicable. He fuppofes it not impoflible that exhalations in earthquakes may augment or leffen the deleterious quality of the air in peftilence. Com. vol. 16, 47.. Sydenham not only agrees with Diemerbroeck, Van Swieten, and others, in afcribing peftilence to occult qualities in the air, but has entered into the fubject of explaining the peculiar fyrnp- toms of difeafes by the influence of an Epidemic conftitution of . the air. His occult qualities have been ridiculed by later phyfi- cians, and fo far as his theory, in this refpect, has been neg- lected, the fcience of medicin has degenerated. If I miftake not, it can be made evident, that one of the moft important, as well as moft difficult branches of medical fcience, is to as- certain the effect of the reigning conftitution of air, on prevail- ing difeafes, and to apply that knowledge to the cure of thofe difeafes. Dr. Mead's treatife on the plague has been much admired and celebrated j yet I will affert, that next to the " Traite de i6 la pefre," a treatife in quarto on the plague of Marfeilles, pub- Iifhed by royal permiflion, it is the weakeft and leaft valuable performance on that fubject now extant. The author acknowl- edges he had never feen the difeafe of which he wrote; and therefore muft have formed his opinions on the obfervations of others. His eflay is intended to demonftrate that the plague is propa- gated by fpecific contagion only, and he attempts to prove that this difeafe, like the fmall-pox and mealies, has been bred in E- gyptor Ethiopia, and thence propagated and entailed on Europe. Works, p. 242 & 3. In fupport of this theory he even goes fo far as to call in quef- tion the unanimous teftimony of hiftorians, who relate that the terrible plague of 1347, 8, 9, and 50, began in Cathay, China. In oppofition to which he " queftions not," that that peftilence originated in Egypt. He alledges that we muft feek the caufe of plague in Egypt and no where elfe. p. 246. He afcribes the plague to the putrefaction of animal fubftances and unfeafonable moifture, heats and want of winds ; but fays " no kind of putrefaction in European countries is ever height* ened to a degree capable of producing the true plague." p. 247 & 8. This author afligns three caufes of plague, ift. Difeafed perfons : 2d. goods tranfported from infected places: 3d. a corrupted ftate of air. p. 25 c. He thinks the caufes mentioned fo obvious that he wonders at authors who r^fort to hidden qualities, fuch as malignant in- fluences of the heavens, arfenical, bituminous or other mine- ral effluvia, with the like imaginary or uncertain agents. p. 249- He does not however deny "11 latent diforders in the air, but confiders them as fecondary caufes only, increafing and promo- ting the difeafe when once bred, but he thinks infection to be the means of its propagation. In this he differs widely from Diemerbroeck who utterly denies that the difeafe is originally derived from infedtion, although he agrees that it may be after- wards communicated from perfon to perfon by contact or ntur '7 approach. Diemerbroeck alfo maintains the latent qualities of the air to be the principal caufe of the plague ; or caufe fine qua non—a point which the facts to be hereafter detailed will moft clearly demonftrate. Dr. Mead fays, " the plague is never originally bred with us, but is always brought accidentally from abroad." p. 261. The fame opinion is afferted moft pofitively in James' Medi- cal Dictionary, and in moft modern publications on the fubject. The compilers of the Encyclopedia fay, " the plague, as is generally agreed, is never bred or propagated m Britain, but al- ways imported from abroad, efpecially from the Levant, LefTer Afia or Egypt where it is very common." Such alfo was the opinion of the celebrated Cullen. Encyclop. art. plague and medicine no. 221. The following fentence in Dr. Mead is very exceptionable, as it is calculated to check a fpirit of free enquiry—a fpirit to which mankind are greatly indebted for improvements in fcience. " It may be juftly cenfured in thofe writers that they fhould undertake to determine the fpecific nature of thefe fecret chan- ges and alterations which we have no means at all of difcover- ing," alluding to changes in the air. p. 249- In oppofition to all thefe great authorities, it will probably be proved, that the plague generally, if not always originates, in the country where it exifts as an epidemic. The common opinion of the propagation of peftilence folely by infection, has had a moft calamitous effect on medicin and on human happinels. It has prevented the refearches of acute modern philofophers and phyficians, who might have been able, by diligence and a comprehensive view of the fubject, to trace peftilence to its real caufes, and to fuggeft the true means of avoiding this terrible fcourge. Thompfon who travelled in Egypt about the year 1734, and whofe account of that country has not been mended by modern travellers, obferves, "" The coming and going of the plague are two things not eafily to be accounted for, notwithltanding wc • c / i8 are aftiired of the facts in a moft unqueftionable manner. That the infection is propagated in the air, and thereby transferred from place to place, feems to be a matter out of difpute ; but how it is generated therein, we are much at a lofs to determine." He proceeds to ftate, like many others, " that the plague is generally brought into Egypt from Conftantinople or by Cara- vans from the fouthern countfies." And on the whole he thinks it rarely generated in that country. Travels, vol. 2, p. 194 & 5- In the Monthly Review vol. 33, there is an account of the plague in Conftantinople, by Dr. Mackenzie, in which are fome paflages worthy of notice. After afferting his opinion that this diftemper can be communicated enly by the touch or near a_;« proach, he adds, " that both here and at Smyrna, the plague breaks out, in fome years, when it is not poffible to trace whence it is conveyed." He fuppofes the difeafe to proceed from " venomous moleculae lodged in wool, cotton, hair, leather and fkins," in houfes not well cleanfed after peftilence ; but that the plague from this fource is not fo fatal as when it comes from abroad. The air he thinks no otherwife concerned in produ- cing the difeafe, than as " a vehicle to convey the venomous particles from one body to another." Dr. Chandler, in his account of a plague in Smyrna, has near- ly the fame idea, as Mackenzie, with refpect to the origin of rJie difeafe. He fays " the plague might perhaps be truly defined, a difeafe arifing from certain animalculae, probably invifible, which burrow and form their nidus in the human body. Thefe whether generated in Egypt or elfewhere, fubfift always in fome places fuited to their nature. They are imported almofl annually into Smyrna, and this fpecies is commonly deftroyed by intenfe heat. They are leaft fatal at the beginning and latter end of the feafon. If they arrive early in the fpring, they are weak ; but gather ftrength, multiply and then perifli. The pores of the fkin, opened by the weather, readily admit them." Baron de Tott in his memoirs obferves " The refeaxches I have carefully made concerning the plague, which I once believ- ed to originate in Egypt, have convinced me, that it would not be fo much as known there, were not the feeds of it conveyed *9 thither by the commercial intercourfe between Conftantinople and Alexandria. It is in this laft city that it always begins to appear. It rarely reaches Cairo, though no precaution is taken to prevent it; and when it does, it is prefently extirpated by the heats, and prevented from arriving as far as the Said. It is like- vrife well known that the penetrating dews, which fall in Egypt about midfummer, deftroy, even in Alexandria, all remains of this diftemper." Vol. 4. page 70. In vol. 1, p. 38 he fays, " that the refearches into the nature of this diftemper have only produced opinions which are feif-con- tradidory or unfupported by fairs."—" There is no difficulty with refpect to the caufes which preferve and propagate it. Both the one and the other may be referred to the dealers in old clothe* in Conftantinople." Du Pauw, in his Philofophical Diflertations on the Egyptians and Chinefe, fpeaks of the plague as a difeafe of Egypt ; and fuppofes the plague at Vienna in 1680, to have been imported from that country.—" Egypt is the hot-bed of the plague—this diforder is not produced by famin—by exact annotations con- tinued during twenty-eight years, we find that it raged five times, without being preceded by any fcarcity of food, and contrary to what I once fufpefted, unreftridted to a periodical courfe." Vol. 1. p. 87, 89. Savaryalledge?, in opposition to the laft mentioned author, that the peftilence is not native in Egypt, and that he confulted Egyp- tians and phyficians who had lived there 20 years, who informed him that the plague was brought thither by the Turks. He fup- pofes Conftantinople to be pow the refider.ee of this dreadful af- fliction, which i; preferved in exiftence by means of old clothes, which, after a plague has ceafed, are diftributed and fold very low by the Jews, and thus the difeafe is propagated. Dr. Alexander RufTel has given an account of the plague in Aleppo in 1742 and 3, and endeavored to afcertain from what quarter the difeafe originated and invaded that city. He feems to think, it always appears firft at Tripoli, Sidon, or on the Sea Coaft. It was aflerted that the great plague of 1719 came from the northward ; but as this fact does not fuit his theory, he, like SO Dr. Mead, in the cafe before mentioned, gives no credit to th* affertion, but adheres to his opinion that all plagues originate in Egypt___At the fame time he is puzzled to trace the difeafe, in any inftance, to that country. See his hift. of Aleppo. Dr. Patrick Ruflel has publiflied a quarto volume on the plague of Aleppo in 1760, and the fubject of quarantine. In this work, he has preferved a number of important facts, but without under- ftandingthe fubject fufficiently to apply them to ufeful purpofgs. All his theory and practical remarks are founded on the vulgar fuppofition of the origin of that difeafe in one or two cities only, and its propagation by fpecific contagion—a fuppofition totally unfounded ; his treatife of courfe will be found of little value, in this refpe ed with tedious diftempers, efpecially the quartan ague. The difeafe made its moft fatal ravages among the flaves, whofe dead bodies lay unburied along the highways. It was not poflible to bury the bodies of the free citizens. Their corpfes lay unburied, untouched by dogs and vultures, and wafted away by corruption. It was evident that in this and the former year, during the great mortality among men and cattle, no vulture was feen." Jn this account, the following particulars are noticeable. 1 ft. That the peftilential air firft produced its effects on cattle, 2d. That the feventh was the critical day—as it ufually is, in modern bilious plague. 3d. That if the difeafe had a favorable crifis on the feventh day, the patient furvived, but the diftemper changed into an au- tumnal 'bilious fever of the quartan type, and long duration—a ftrong evidence of what I have before remarked that, if peftis and peftilentia arc difeafes of a diftinct fpecies, the Roman peftilence was the bilious plague. 4th. This peftilence was, as ufual, moft mortal among the lower orders of people. 5th. Carnivorous animals would not touch the dead bodies, and vultures deferted the atmofphere of Rome. The laft fact is common in great plagues ; but in plagues of a lefs malignancy, animals do not quit the infected places. Thefe facts fecm to indicate that birds perceive the peftilential ftate of air, before it becomes fenfible to the human fpecies. It feems that the vultures difappeared, the firft year, while the peftilence was confined to cattle ; and there can be little doubt, that the del- icate organs of fowls perceive the derangement of the air, whether 5« the caufe may be, the infufion into it of a peftiferous vapor, or the abftraction from it of a portion of the vital principle, before its effects are vifible in larger animals, and before the air is ren- dered offenfive by the carcafes of difeafed and dead animals. This was one of thofe violent and long continued plagues of which hiftory has recorded many inftances : and the Romans on this occafion, faw many prodigies. It is difficult, in fome ca- fes, to diftinguifh, in the relations of hiftorians, truth from vul- gar report ; and philofophy muft guard againft the illufions of credulity and terrified imaginations. I take no notice of the monfters born, and an ox's fpeaking, on thefe occafions. At the beginning of the late American war, many fimilar prodigies were announced and believed by the ignorant and credulous. But fome of the phenomena, enumerated by Livy among prod- igies, in all probability, had a real exiftence, for it will be re- lated hereafter that fimilar appearances have been obferved, in modern times, during peftilence, and appear evidently to have a connection with its caufes. During the plague above mentioned, a bow was feen in the fky, in a ferene day, extended over the temple of Saturn in the Roman forum ; three funs or haloes appeared, and at night many torches, or meteors defcended in Lanuvium. There is ftrong evidence for believing thefe phenomena to be occafioned by a vapor emitted from the earth, in fuperabundant quantities, and which there is reafon to think, may be the caufe of peftilen- tial difeafes ; or there may be fome changes in the combination of fubftances compofing the atmofphere. At the clofe of this peftilential period, in 581, Apulia was deluged by fwarms of locufts ; as the Pontine territory had been the year before. So deftructive were their ravages, that the Praetor Sicinius was fent with an army to drive them away. Livy, b. 42. 2 & 10. Orofius b. 4 relates, that a moft violent plague defolated Rome in the year 610 and B. C. 144. The dead bodies -lay pu- trefying in the houfes and ftreets, and rendered it impoflible to approach the city. In the preceding year appeared a remarkable comet. As we come down to the more authentic periods of hif- tory, this phenomenon will more frequently occur. 57 It is again neceffary to remark a difference in the chronology of different authors. Seneca places the appearance of this comet, which he defcribes to have been as large and luminous as the fun, " Poft mortem Demetrii Syriae Regis, paulo ante Achaicum Bellum"—after the death of Demetrius, king of Syria, and a little before the Achean war. N4t. Queft. lib. 7.15. Demetrius was flain, B. C. 151, according to common chro- nology, and the Achean war was in the year when Carthage was taken and deftroyed by Scipio, B.C. 146. The appearance of the comet therefore fhould be placed in the year preceding, or £47, correfponding with the year of Rome, 607. And this is proba- bly correct, for it is agreeable to general obfervation, that a comet appears early in the peftilential period, and often precedes its moft calamitous years,—The Encyclopedia affigns it to the year 146. Seneca remarks that at firft it appeared fiery and red, emitting a bright light, fo as to overcome the darknefs of the night. Gradually its magnitude leffened and its brightnefs vanifhed. This plague was ftill more deadly than that in which CamilluS died. Muratori, vol. I. In the year of Rome 628, and B. C. 126, hiftorians relate, that a moft dreadful peftilence arofe in Africa, from dead lo- cufts. Thefe animals were brought towards Numidia and Utica, by a ftrong eaft wind, in fuch innumerable multitudes, that they devoured every green thing—not fparing even the bark of trees. They were driven by the fouth wind into the Mediterranean, and being waflied on fhore, in the hot feafon, they putrefied, and caufed a moft deadly plague. It is related that 800,000 perfons perifhed in Numidia alone ; 200,000 on the fea coaft of Carthage and Utica, and 30,000 of the Roman troops. No lefs than 1500 dead bodies were carried out of one gate of U- tica, in a Angle day. l.ivy, Epit. 60. Orofius, lib. 5. P. Diac. Auguft. Hift. 813. ■ Authors afcribe this plague to the dead locufts ; and doubt- lefs that caufe had if, influence. At the fame time, there is no H neceflity of reforting to the locufts, for this was a time of gene- ral peftilence. The fame ftate of air or other elements which favored the generation of difeafe, firft exifted, and produced this unufual number of locufts. This will appear in fubfequent parts of this hiftory. Orofius gives a moft hideous account of the peftiferous ftate of air from the locufts. He avers that birds, cattle and wild beafts perifhed by means of the corruption of the air, and thus in- creafed the evil. He remarks further that, altho locufts had often appeared in his days, in great numbers, yet they never be- fore had done more mifchief when dead, than when living, fo as to caufe mankind to wifh they had not perifhed. We muft accede to the opinion of the ancients that the ftench of the locufts wasone caufe of the peftilence; it ispoflible that no epidemic difeafe would have been excited without that caufe ; but it is equally true, that in a healthy ftate of the atmofphere, no putrefaction of dead bodies has ever been known to produce an epidemic peftilence. It may be powerful enough to excite difeafe within a fmall extent of its own atmofphere ; but if no other caufe of difeafe exifts, it will not extend beyond that in- fected atmofphere. The appearance of immenfe multitudes of locufts, during peftilence, is a curious fact in natural hiftory, and well deferves inveftigation ; but thefe animals do not always precede the ap- pearance of the difeafes of the fame period, nor do they often perifli in fuch collections as to be the caufe of thofe difeafes. The common idea in Arabia, is, that they are generated by heat and drouth. Cold and rains are fuppofed to deftroy their eggs. About the beginning of this deftructive period, appeared a comet. The Encyclopedia mentions two, in the year of Rome 629, and B. C. 125. But it is probable this is a miftake of the compilers. The univerfal hiftory places one under the year 630,'ajrtl a fecond under the following year, quoting Juftin, for au- thority. ' But Juftin mentions two comets, one at the birth of Mithridates, another in the year he began to reign. Now Mi- thridates was about eleven or twelve years old when he came to 59 the throne, in the year of Rome 631, and B.C. 123. Of courfe the firft comet muft have been-about the year 620, and B.C. 134. It is no inconfiderable proof of the truth of Juftin's account, andof the accuracy of our chronology in this particular, that there was an eruption of the great volcano of Sicily, in both the pe- riods when thefe comets are faid to have appeared. In the year 620, and B. C 134, there was an eruption of Etna, tho not mentioned by Juftin ; and this was the year of the firft great comet, and of the birth of Mithridates. Nine years after, in 629, there was a fecond eruption of Etna. The laft year cor- refponds nearly with the period in which Mithridates began to reign, allowing him to be eleven years old, and with the ap- proach of the fecond comet. This laft comet produced moft tremendous effects, as we might expect from its magnitude, and proximity to the earth. The following is Juftin's defcription of it. " Nam et eo quo genitus eft anno, et eo quo regnare primum ccepit, ftella cometes, per utrumque tempus, 70 diebus ita luxit, ut caelum omne fla*: grare videreter." For 70 days the heavens appeared to be in a flame. . Lib. 37. a- The eruptions of the volcano were equally remarkable. The lava from Etna laid wafte the city and fuburbs of Catana. u JEtna ultra folitum exarfit, fays the hiftorian; Catanam ur- bem finefque oppreflit." Orofius, lib. 5. In Paulus Diaconus we have a relation of lingular facts in re- gard to the eruption of Etna. Globes of fire were thrown from the Crater. Lipari, a fmall volcanic ifland on the north of Si- cily, became fo heated, during the eruption, that the rocks were diffolved, tho it is not faid that this ifland difcharged any fire. The water of the neighboring fea was fo heated as to kill the fifh, and melt the pitch on the decks of veffels. Dead fifh ap- peared on the furface of the water, and many perfons, who were near the ifland, were fuffocated with heat. This author places the appearance of the locufts which cau- fed the plague in Africa, in the year after the eruption of Etna. 66 Others place this event, a year before the eruption. It L mucll to be regretted that authors have been fo carelcfs of the chronoi- ogy of important phenomena, on the order of which may de- pend important principles. This however is certain, that all the great agitations of nature here related belong to the fame period, and it is not furptifing that they were attended with moft mortal peftilence. For authorities fee Livy, Fpit 60. Orofius, lib. 5. P. Diaconus, in Auguft. Hift. 813. Juftin, lib. 37. 2,3. Ufh'er'a Annala, 498. Muratori, vol. 1, p. 26. The foregoing period of peftilence was one of the moft dread- ful on record. It will be found invariably true, in every period of the world, that the violence and extent of the plague has been nearly pro- portioned to the number and violence of the following phenome- na—earthquakes, eruptions of volcanoes, meteors, tempefts, in- undations During the civil wars excited by Sylla and Marius, the armies loft ten thoufand men by the plague, ia the year of Rome 66$, and B.C. 89. Univerfal Hift. Vol. 13. 59. Vcl. Paterc. lib. 3. 21. It muft have been during this period that the comet appeared which is mentioned by Pliny. Nat. Hift. lib. 2. cap 25. " Civili motu, Octavio Confule," for this was the year, in which Octavius was Conful. This period was preceded by an extraordinary collifion and difrupture of two mountains, and the burfting of fire from the chafm, in the territory of Modena. Pli- ny affures us, this was feen from the Emilian way, by an immenfe number of Roman knights and others, Pliny Nat. Hift. lib. 2. 83. With this period correfponds the eruption of a volcano in Hi- era, one of the iEolian ifles, north of Sicily, now called Lipari, which burnt for feveral days, and the very fea around it appeared to be fire. Pliny fays this was during the Social War. Lib. 2. 106. The year B. C. 44 was diftinguifhed by the death of Julius Cefar, by the hands of configurators; foon after which appeared a comet, fuppofed to be the fame which appeared in 6t reSo, whofe period is calculated to be 575 years. If this is its period, it muft have been feen in the year B. C. 176*, in the reign of Ogyges, when Attica was inundated and rendered barren for a number of years ; and when the planet Venus is faid to have changed her figure, color and courfe. When we furvey the uniform effects of comets in terapefts and floods, and compare the traditional account of that event with the terrible inundations which have happened in Greece at other times, and efpecially with that in the time of Thucydides, which rent Ata- lanta from the main land ; which events all took place during the approach of comets; we areconftrained to believe the fact of the Ogygean deluge, and fable rifes to the dignity of authentic hiftory. This inundation might have happened during the approach of fome other comet, but the probability is, that it was during that of the comet under confideration, which fixes the time of the Ogygean flood, in the year B. C. 1767. This circum- ftance may fcrve to correct the chronology of the early events in Greece. See Jackfon's chronology vol. 3. 312. Its next appearance muft have been in the year A. C. 1193, when Electra, one of the pleiads, abandoned her filler orbs, and fled from the Zodiac to the north pole. Its third appearance correfponds with the year A. C. 618, the year of the terrible comet of the Sybill, fays Gibbon ; and its fourth, is the one under confideration. Its fubfequent appear- ances A. D. 531, 1106 and 1680 will be hereafter mentioned. All the periods here named, which come within the limits of authentic hiftory, have been remarkable for peftilence, earth- quakes, inundations or other great phenomena. Such was the fact in 44 and 43. There was a terrible inundation of the Tyber, a violent earthquake, many unufual phenomena in the fky, and in the year 43, a violent eruption of Etna___Pefti- lence, as ufual, accompanied thefe events. But another phenomenon, the palenefs or defect of light, in the fun, deferves more paiticular attention. Pliny afferts that this pale color lafted almoft a year. His words are, " Fiunt |>rodigiofi et longrores folis defectus, qualis occifo dictatore Ca> 6± fare et Antoniano bello, totius pene anni pallore continue." Nat. Hift. lib. 2. 30.—Virgil and Ovid, who were eye wit- neffes of this phenomenon, have both defcribed it, with the Other pTodigies of this period. " Ille (fol) etiam extindto miferatus Caefare Romam, Cum Caput obfcura nitidum ferrugine texit."-— Georg. lib. 1. 466. " Phoebi quoque triftis imago Lurida follicitis praebebat lumina terris." Mctamorph. lib. 15. 785. The words ferrugo and lurldus give us an exact idea of the color—a palenefs tinctured with the color of ruft. A fimilar defect of light in the fun occurred at the time of the next ap- pearance of this comet, A. D. 531, as will be hereafter related. The fact is curious. It is well known that this comet ap- proaches very near to the fun ; but whether the defect of fplen- dor in the fun was the effect of the attractive powers of the comet, or of an alteration in the electrical atmofphere of thefe bodies ; or whether it was occafioned by an alteration in the ter- reftrial atmofphere, is a queftion not eafily folved. It might have been owing to a vapor, like that which overfpread Europe in 1783. This period was marked with famin alfo, with fhooting ftars, and numerous prodigies. See Virgil and Ovid in the paflages quoted. See alfo, Zonoras' Annals, lib. zo. Uflier's An. p. 680. The comet appeared in 44 and alfo the peftilence—the erup- tion of Etna in 43 B. C. and therefore fubfequent to the other events. Indeed it is more generally the cafe, that the volcano does not emit fire until fome time after the appearance of the plague. To this however there are exceptions. Moft of the great plagues appear two or three years, with different degrees of violence ; and during this period, volcanoes difcharge im- menfe quantities of lava. By a paragraph in Ufher's Annals, p. 684, it appears the winter following the appearance of this comet, was fevere. ■*3 The next peftilential period commenced in the year 30 B. C. An eruption of Etna, which laid all the neighboring towns in ruins, marked the commencement of this period, which how- , ever was preceded in 31 by an earthquake in Judea, in which thoufands of people perifhed in the ruins of their houfes. About the fame time appeared, fays Dion Caflius, " thofe meteors which the Greeks call cOmets." Thefe phenomena were fol- lowed by a peftilence in Jerufalem, which deftroyed a great part of the nobles and people of the Jews. The fame period was marked by a great inundation of the Tyber, which fpread over the low grounds of Rome, and was confidered as an omen of the future power of Auguftus. Dion Caflius' Univ. Hift. 10,415. Uflier'j Annals, 766. By a curious circumftance, we learn that a hard winter and peftilence afflicted Rome at this period. The Emperor Octavi- us Auguftus, in his 5th Confulfhip, B. C. 29, had formed the defign of refigning the empire. Horace, the Poet, his friend and flatterer, endeavored to diffuade him from this purpofe, on account of the prodigies which happened at the beginning of the year, which was the v/inter of the year 30 B. C. and correfpond* exactly with the appearance of the comet. Among thefe prod- igies, the poet enumerates an abundance of fnow, terrible hail, thunder and lightning, and a deftructive inundation of the Tyber. " Jam fatis terris nivis, atque dirze Grandinis mifit Pater—&c." See the 2d Ode of the firft book, which is worth the notice of the philofophic reader, on account of the defcription of the inundation, which proceeded from zfwell of the fea. " Vidimus flavum Tiberim, retortis Littore Etrufco violenter undis." It is a fact of which there is full evidence, that during the ap- proach of comets, not only tempefts are more violent, than at other times, but the ocean fwells without winds—the tides are much higher and high tides are more numerous. The ancients 64 took notice of this fact, and it came under my own obfervation, during the approach of the comet in 1797. In the 21 ft ode of the fame book, Horace addreffes Apollo who " drives war, famin and peftilence from the Roman people and the Emperor, to the Perfians and Britons." This paffage is proof th.it the Romans found peftilence in Brit- ain ; but the Britons, at that time, had no trade, except with the coaft of France. How or from what quarter, they Imported the Infealon, is left for the folution of Dr. Mead's followers. In the year B. C. 25, according to the Univerfal Hiftory, a violent peftilence raged in Rome, an inundation laid a great part of the city under water, lands were left untitled and a famin en- fiied. The fame year, the plague raged in Paleftine, which was pre- ceded by a fevere drouth and a dearth of corn. A hard winter is mentioned about the fame time, but the order of this event is not recorded. Univerfal Hilt. vol. 13.502. Uflier's Annals, 772. Dufrefnoy's Chro, This peftilence was preceded the year before, by " epidemic diftempers which proved fatal to many." This fact is important, and will hereafter be found very material in determining the caud- les of epidemic peftilential difeafes. It goes to prove a progref- fivenefs in the peftilential ftate of air, or general contagion. And this inftance, among many to be hereafter fpecified,demonftrates thatthe plague was not produced by the famin, according to vulgar opinion in almoft all cafes of this kind. Had no malignant dif- eafe preceded the plague, and had the plague followed dofe on the heels of famin, we fhould have ftrong ground to believe fan\- in to be the caufe of the plague ; and a feries of fimilar facts might eftablifh that as a principle or law of nature. But it appears, that the malignant diftempers, which are found to be the conftant precurfors of peftilence, were epidemic, in the year preceding the famin—a demonftration that the general caufe, in the ftatg of air, exifted anterior to the dearth. *5 SECTION III. Hiftorical view vf peftilential epidemics from the Chriftian era, to the year 1347. XJLT the clofe of the reign of Auguftus, about the year 14 or according to fome authors 16 of the Chriftian era, there was a great famin in Rome, and a comet is mentioned, near the fame time, by Dion Caflius. This was followed by a moft terrible peftilence in the eaft, during which twelve cities of Afia Minor were overthrown by earthquakes. Of thefe ca« lamitous events, the following is the account recorded by Taci- tus,1 An. lib. 2. 47. « Eodem anno, duodecem celebres Afiaa urbes conlapfae nocturno motu terras, quo improvifior gravior- que peftis fuit. Neque folitum in tali cafu effugium fubveniebat in aperta prorumpendi, quia didudtis terris hauriebantur : Sedif- fe immenfos montes, vifa in arduo quae plana fuerint, effulfiffe inter rainam ignis memorant." It is a circumftance not to be overlooked that the plague was prevalent, anterior to this dreadful earthquake, as the hiftorian remarks that this cataftrophe rendered the ficknefs more fevere and lefs tolerable. Such is the ufual courfe of thefe calamities ; the peftilence appears, before the moft deftructive fhocks of the earth, which rarely fail to occur, during its prevalence. It is to be obferved alfo that men obtained no fecurity, in this in- ftance, by flying to open places, for the earth opened and fwal- lowed them up—fire alfo iffued from the earth. Large raoun-j tains fubfided to plains, and plains were thrown into mountains. Tacitus An. lib. 2. 47- PHn. lib. 2. 84- Eufeb. Chron. 201. Uiher's Annals, 811. In the year 40 of the Chriftian era, there was an eruption of Etna, which frightened Caligula out of Sicily and which wa§ I 66 followed by univierfal famin in Rome and the eaft.* This waj the famin foretold by Agabus in Acts xi. 28, im the reign of Claudius Cefar. A peftilence, at the fame time raged in Bab. ylonia, and multitudes of Jews, on account of it, withdrew to Seleucia. Suetonius in Calig. Univ. Hift. vol. 14. Ufher's An. 864, 868. During this famin and peftilence, a comet was vifible in the year 42. Short on Air, vol. *. 170. The clofe of the reign of Claudius and the beginning of the reign of Nero, A. D. 53 and 4, were marked by a fimilar train of phenomena and calamities. A comet is noted by Sue- tonius and Pliny about the year 54, the year in which Claudius was poifoned. Tacitus relates that people were alarmed by fre- quent fhocks of earthquakes, which demolifhed many buildings, and great dearth of corn prevailed in Rome and Greece. Pliny records that three funs, by which are doubtlefs intended, halos or mock funs, appeared the fame year. Thefe were confidered by the ancients as prodigies ; but tho common phenomena, they are remarkably luminous, and frequent in the periods of pefti- lence. Tacitus Annals, lib. 12. 43. Plin. Nat. Hift. lib. 2. 31. Sutt. in Claud. Fundlius Chronol. This period was fickly, tho not recorded as peftilential. Su- etonius remarks, " Ex omnium Magiftratum generi, plerique mortem obierant." Many of all kinds of public officers died ; by which we infer that the year was fickly. In the reign of Nero occurred the next peftilential period. Two comets are noted, one A. D. 62 and a fecond in 66. In the year 62, Laodicea was overwhelmed by an earthquake. In the year 68, occurred a moft violent tempeft in Campania which deftroyed villages, trees and grain ; and a violent earthquake. At the fame time, raged a mortal plague in Rome, which is faid to have carried off 30,000 people ; but by the defcription of its * Short places this in the 49th year of the Chriftian era ; altho Caligula was killed ri the year 41. No dependence can be placed on the dates of events, -ou iu in Short on Air; and I cannot vouch lor their corxectnefs, where I have not other uuthoritv. 67 ravages, it is probable the number was much greater. Tacitus remarks that the " houfes were filled with dead bodies and the ftreets with funerals ; neither age nor fex was exempt ; flaves and ingenuous plebeians were fuddenly taken off, amidft the la- mentations of their wives and children, who, while they aflifted the fick, or mourned over the dead, were feized with the difeafe, and perifhing, were burnt on the fame funeral pile. To the knights anil fenators, the difeafe was lefs mortal, tho thefe alfo fuffcred in the common calamity." As Rome, at the time under confideration, contained rftore than a million of inhabitants, fo mortal a plague muft have ex- tinguifhed a much larger number than 30,000 people—it is not improbable, a numeral or figure has been omitted by the tranf- cribers of the original hiftory. The earthquakes of this period were experienced in Afia Mi- nor, at Laodicea and Hierapolis. Seneca mentions that a flock of 600 fheep were killed by the peftiferous vapor, difcharged during the earthquake in Italy. Dion Caflius relates, that at this period, a moft formidable in- undation laid wafte the Egyptian coaft. It muft not be omitted that the violent tempeft in which St. Paul was fhipwrecked on the ifland of Melita, now Malta, was in the year 61 or 62, during the approach of the firft comet. Tacitus remarks, that no vifible caufe could be afligned for the peftilence of this period ; " Nulla Cceli intemperie quae occur- reret occulis." No remarkable feafon had occurred, to which this diftemper could be afcribed. We fhall find, in fubfequent periods, diftinguiflied writers making fimilar remarks. The rea- fon is, thefe authors did not take a view fufficiently comprehen- Gve of the operations of nature ; and if the caufe of plague could not be found, very near In time and place, they did not obferve it. It is true, that an extraordinary feafon does not always precede or attend peftilence, in a particular place ; but by extending our view of the fubject, to general caufes,operating over whole quar- ters of the globe, and perhaps over the whole globe ; and con- fidering the caufesjJSr invifible, and acting for a feries of years, 6B the whole myftery is unfolded.—-Such may be the refult of this inveftigation. For authorities refpecting the laft period of peftilence here « noticed, fee Tacitus, An. lib. 15.47- lib. 16. 13. Suet. in Nero. Seneca, Nat. Queft. 6 and 7. Baronui?, vol. 1. 62a Plin. Nat. Hift. lib. 2. S3. Ufher's Annals, 89a. Fundi. Chron. Orof. lib. 7. Univerfal Hift. vol. 14. 439. Magd. Ec. Hift. lib. 2. 13. Seneca places the great earthquake in Campania under the Confulfhip of Regulus and Virginius, which, according to com- mon chronology, was in the 65th year of the Chriftian era. The next peftilential period is one of the moft remarkable in all the circumftances, that is recorded in Hiftory. In the year 79 [fome authors fay a year later, but the diffe- rence is of no moment, as they agree in the order of the events related] juft before the death of Vefpafian, appeared a comet with a long coma in the month of June. On the firft of Novem- ber following, a moft tremendous ebullition of fire and lava iffu- ed from Vefuvius and laid wafte the neighboring country. At the fame time, happened a violent earthquake, which buried the cities of Herculaneum and Pompeium ; and fo fudden was the fhock, that the people, who were attending a play, had not time to quit the theater, and were all buried in a mafs. This dreadful cataftrophe was preceded by rumbling noifes in the earth, and the earth was heated to a great degree. Violent agitations of the fea, thunder and lightning alfo announced the approach of fome dreadful event. The eruption lafted three days, during which time fuch im- menfe quantities of afhes and fmoke were difcharged, that day was turned into night, and the afhes were driven by different winds to Rome, Syria and Africa. The agitations of the earth and the elements were tremendous andfrighful. Baronius remarks, that fome perfons fuppofed the world would be reduced to chaos, or confumed with fire. The fifh in the neighboring feas were deftroyed. This explofion of fubterranean fire was precededhy a fevere drouth in Italy. The next year,' 80, was remarkable for a terri- ble inundation in England ; the Severn oversowing a large tract of country, and deftroying multitudes of cattle. £r) Thefe violent effects of fubterranean fire were attended by one of the moft fatal plagues recorded in hiftory. A remark of Dion is here very important. He fays that the " Afhes from Vefuvi- us caufed, at the time, only flight indifpofitions or difeafes ; but afterwards produced an Epidemic diftemper." The remark is incorrect, in afcribing even flight difeafes to afhes ; but it leads to a conclusion, which is of moment. The flight complaints which prevailed in the autumn of the year of the eruption, com- pared with modern obfervations, appear to have been the precur- fors of the plague, which broke out the next year, and as au- thors affcrt, deftroyed, for fome time, 10,000 citizens ©f Rome in a day.—The fame year, while the Emperor Titus was view- ing the ruins in Campania, a fire broke out in the city, which laid in afhes a great number of buildings. The order of the events in this period was, a comet, drouth, flight difeafes, and an eruption of Vefuvius, with the earth- quakes, the firft year.—In the fecond, appeared the peftilence with its moft malignant effects. In this eruption of Vefuvius, the firft recorded in hiftory, per- ifhed the elder Pliny ; and the Emperor Titus fell a victim to his paternal care of his fubjects. Suetonius, 23. Aurcl. Vidtor. Epit. Dion Caflius Pliny Epif- Baronius An. vol. 1. 713. Magd. lib. 2.14. In the year 90 appeared a comet. The plague is faid to have appeared in the north of England in 88, and in 92, to have de- ftroyed 150,000 lives in Scotland. Short, vol. 2. 207. In 102 a plague is faid to have arifen from dead fifh driven on fliore, but I have no other particulars. In the year 107 four cities of Afia, two in Greece and three in Galatia, were overwhelmed by an earthquake. A comet is mentioned by Short in 109, but as I have not found the original authority, I cannot depend on the accuracy of the chronology. It is probable that thefe phenomena occurred within the fame year ; and there is the more reafon to believe this, as different and refpectable authors differ two or three years in the chronology of Roman hiftory. The next event to be related, is a re- markable inftance of the truth of this obfervation. 2L Short mentions a plague in Wales in 114 which deftroyed 45,000 lives ; but I have not the hiftory of the facts. In the reign of Trajan, the city of Antioch was almoft to- tally demolifhed by an earthquake. This emperor was in the city at the time, and narrowly efcaped with his life. Some au- thors place this event ih the year 114; others in 115; but Ba- ronius has proved by an ancient infcription, that it happened under the confulate of P. Vipftanus Meffala and M. Virgilianus Pedo ; which brings the event to the year 117. A comet was vifible the fame year. The earthquakes of this period were extremely violent—ma- ny cities were overthrown, mountains funk, rivers were dried up and new fountains appeared. Aurelius Victor adds to thefe calamities a great inundation of the Tyber, violent peftilence and famin ; but to which of the periods, the year 107 or 117, he alludes, is not quite certain, tho probably to the latter. " Terrae motus gravis per provin- eias multas, atroxque peftilentia, famefque et inundia facta funt." To remedy the danger from fire and earthquakes, Trajan limited the height of houfes in Rome to 60 feet; and for that regulation obtained the title of " Father of the Country." The great earthquake at Antioch was accompanied with fierce winds, a circumftance not very common ; it being more ufual that fhocks of the earth happen during a perfect ferenityand tranquillity of the atmofphere, unlefs in the vicinity of volca- noes. Aurel. Victor. Epit. Trajan. Dion Caflius. Baronius vol. 2.55. Echard's Rom. Hift. vol. 2. 276. During the time that Trajan was making war on the Agarini, a people of Arabia, which had revolted from the Roman gov- ernment, flies in myriads appeared and covered every veffel and utenfil, fo that the Emperor was compelled to abandon the ex- pedition. This was near the time of the earthquake which de- ftroyed Antioch. Baron. 2. 54. Magd. Cent. 2. 13. This fact ought not to be omitted ; as the generation of innu- merable infects is one of the phenomena which generally attend a great peftilence —The fame feafon was marked by terrible ftorms of wind, rain and hail-ftones of unufual fize. The win- 7* ter fucceeding that in which Antioch was deftroyed, was fo tempeftuous, and the Tigris fo fwelled by deluges of rain, that Trajan's army fuffered extreme hardfhips and great loffes, in his expedition into Afiyria. Under the year 115, I find mentioned a* fudden and violent inundation of the Severn in England, which drowned people in their beds, and deftroyed 5000 head of cattle. Perhaps phi- lofophy will place this event, under the year of the earthquake at Antioch ; whichever may be the true year, 115 or 117. In the chronological tables, a great earthquake in China is mentioned under the year 114—the year of the plague in Wales, Under the Emperor Adrian, fay the compilers of the Mag- deburgh hiftory, from Eufebius, the greateft part of Nicomedia and Nicea was overthrown by earthquakes ; and not long after, Nicopolis and Cefarea were totally overwhelmed. Functius af- figns the fate of Nicomedia to the year 121, and that of Nicop- olis to 129. By another writer is noted a comet in 127, and a plague in Scotland. Short, vol. a, 207, In 13 7 appeared a comet, followed by the plague.—In this year or the fubfequent one, the Thames was almoft dry. The plague again made great havoc in Scotland in 146.—A.n eruption of fire from Lipari happened in 144. In the year 153 happened a fevere winter of three months, which covered the Thames and all rivers with ice. In the reign of Antoninus Pius, A. D. 154, occurred an earthquake which proftrated fome towns in Afia and Rhodes. A comet appeared nearly at the fame time, and a peftilence in Arabia, together with an inundation of the Tyber. Julius Capitolinus. Magdeb. Cent. 2. 13. Baronius vol. 2. 130. Of the general and fatal peftilence in the reign of Marcus Aurelius Antoninus and Lucius Vents, we have many accounts. It appeared in Rome in 167, but its origin was in Afia, a year or two earlier. Ammianus Marcellinus, the philofophic foldier, relates that this plague originated from the foul air of a fmall box or cheft, which a Roman foldier had opened, in fearch of plunder, after the taking of Seleucia. Julius Capitolinus men- tions the fame fact on the authority of mere vulgar report 01 tradition. " Et nata fertur peftilentia in Babylonia, ubi de templo Apollonis ex aicula aurea, quam milis forte inciderat, fpiritus peftilens evafit, atque inde Parthos orbemque compleffe." A. Marcellinus gives a more particular account of this event, " Milites fanum fcrutantes, invenere foramen anguftum, quo re- ferato, ut pretiofum aliquid invenirent, ex adyto quodam con- clufo a Chaldoeorum arcanis, labes primordalis exfilivit, quae in- fanabilium vi concepta morborum, ejufdem Veri et Marci Anto- nini temporibus, ab ipfis Perfarum finibus, adufque Rhenum, et Gallias Cuneta contagiis polluebat et mortibus." That a clofe box or other confined place, which might have been fhut for ages, fhould contain a peftiferous vapor which might deftrey the life of the man that firft opened it, is not only poflible, but very probable. But that this trifling quantity of nox- ious air fhould be fufficient to generate a univerfal peftilence from the confines of Perfia to Gaul, is a vulgar notion, precifely re^ fembling the modern opinion that the plague is conveyed from country to country, in bales of goods. The hiftorian adds, that the Emperor returned to Rome, and " luem fecum deferre videreter," feemed to carry the plague with him. But the Romans paffed only from Seleucia to Rome ; whereas the plague raged over the whole earth ; fo that the dif- eafe muft have originated in other countries, through which the Emperor did not pafs, and from other caufes than the noxious air of a little box. It raged in Gaul and in Scotland. By attending to the phenomena of the phyfical world, during this period, we fhall find caufes fully adequate to the effect, with- out reforting to the temple of Apollo in Seleucia. The ftate of the elements was deranged, and nature was every where agitated. An inundation of the Tyber at Rome laid all the low grounds, and a part of the city under water, fweeping away people, build- ings and cattle, and defolating the fields. Famin and earth- quakes marked the fame period. The air became infalubrious, and myriads of caterpillars and other infects overran the earth and devoured vegetation. 73 The peftilence' was violent and mortal,. correfponding with thefe fymptoms of derangement in the elements. In Rome, at one time, it is related, that the mortality extended to ten thou- fand perfons in a day. Its precife duration, I do not find to be fpecified by the hiftorians ; but it continued for a number of years ; in the midft of which appeared a comet, about the year See Am. Marcelhnus, lib. 23, and Julius Capitolinus, in Vero. Aug. Hift. j80. Hift. of Emperors by Pedro Mexise, p. 172. Echard's Rom. Hift. vol. 2. 315 to 322, who is more correct than Gibbon. Of the fymptoms of this defolating plague, I find no account, except that the patients had a light fever, and a gangrene appear- ed on the extremities of the feet. It is proper here to notice a paffage in Gibbon's Hift. vol. r. chap. 3, which defcribes, as halcyon days, the period of the world in which this calamity occurred. The following are his words. " If a man were called upon to fix the period in the hiftory of the world, during which the condition of the human race was moft happy and profperous, he would, without hefita- tion, name that which elapfed from the death of Domitian to the accefiion of Commodus ;" that is, from the year 96 to 180. It is certain that, at this time, the Roman Empire was in its glory, and governe'd by a,feries of able and virtuous princes, who made the happinefs ef their fubjects their principal object. But the coloring given to the happinefs of this period, is far too brilliant. The fuccefs of armies and the extent of empire do not conftitute exclufively the happinefs of nations;and no hifto- . ian has a title to the character of fidelity, who does not com- prehend, in his general defcriptions of the ftate of mankind, moral and phyfical, as well as political, evils. During the period mentioned by Gibbon, not only Antioch, wi'.h the lofs of moft of its inhabitants, amounting probably to more than 100,000, but thirteen other cities were demolifhed by earthquakes. In the famous revolt of the Jews under Tra- jan, hiftorians relate that 450,000 Romans were maffacred in 6yria, Cyprus and other countries ; and in the wars undertaken by Adrian to fubduethem, it is eftimated that 50 cities and 985 K 74 towns were deftroyed, and 580,000 men loft their lives by famin, difeafe and the fword. The reign of the Antonines was diftinguifhed for multifarious and fevere calamities. The de- fcription of them, by Aurelius Victor, ought to be given in his own words. Speaking of the Emperor M. Antonine, he fays, *' Nifi ad ilia tempora natus effet, profecto quafi uno lapfu ruiffent omnia flatus Romani. Quippe ab armis nufquam quies erat: perque omnem orientem, Illyricum, Italiam, Galliamque bella fervebant. Terrae motus non fine interitu civitatum, inunda- tiones fluminum, lues crebrae, locuftarum fpecies agris infefhe, prorfus ut prope nihil, quo fummis angoribus- atteri mortales fo- lent, dici feu cogitari queat, quod non illo imperante faevierit." Epit. of the lives of the Emperors. " Unlefs he, M, Antonine, had beep born at that juncture, the affairs of the empire would have fallen into fpeedy ruin : for there was no refpite from military operations. War raged in the eaft, in Illyricum, in Italy and in Gaul. Earthquakes, with the deftruction of cities, inundations of rivers, frequent plagues, a fpecies of locufts ravaging the fields ; in fhort every calamity that can be conceived to afflict and torment men, fcourged the human race, during his adminiftratian." How can that be a " happy and profperous condition of men," in which they were fabject to continual wars, to maffacres, to the ravages of infects, and to a feries of plagues, which deftroy- ed probably one fourth of the inhabitants of the globe ; and when the Roman empire was upon the brink of ruin ? And how can a writer be efteemed as a hiftorian, who fubftitutes the flow- ers of rhetoric for fober truth, and farifices fact to embellifkment ? In the year 173 a peftilence raged in the Roman armies, which threatened them with extermination.—This appears to have been a continuation of the plague before defcribed. It prevailed in Rome in 175 and 178. "• v Tuncl. Chroaol. Short, vol. 2. A fevere winter in 173 produced famia in England, where the fnow covered the earth for 13 weeks. "In 181 a comet was vifible, and in 182 Smyrna was almoft ruined by an earthquake. The plague prevailed in Rome in 183, ibid. 75 In the reign of Commodus, about the year 1S7, Rome was -Again afflicted with a fevere plague, which was felt alfo in all parts of Italy, tho with lefs mortality than in the city. Hero- dian, lib. 1, gives the following account of it. " A great pef- tilence raged throughout Italy at that time, but with moft vio- lence in the city, by reafon of the great concourfe of people affembled from all parts of the earth. The mortality among men and cattle was great. The Emperor, by advice of certain phyficians retired to Laurentum, on account of the coolnefs of the place which was fhaded with laurels, from which circum- ftance it derived its name. It was fuppofed alfo the effluvia from the laurels acted as an antidote againft the contagion of the diftemper. The people in the city alfo, by advice of phy- ficians, filled their nofes and ears with fweet ointments, and conftantly ufed perfumes, for in popular opinion, they occupy the paflages of the fenfes, with thefe odors, and fhut out the corrupt air; or if they do not wholly exclude it, they over- power its influence by fuperior force. But thefe things did not check the progrefs of the difeafe, and men and cattle continued to perifh." The deaths amounted, in Rome, to 5000 in a day, for a confiderable time. A famin prevailed at the fame time, and hiftorians afcribe it to Cleander, the minifter of Commodus, who had monopolized the corn, to compel people to purchafe of him at an advanced price. Dion Caflius however fays, the year had been unfruitful. The peftilence continued three years. Indeed we may here remark once for all, that when we read of a plague of great extent and violence in any part of the world, under the date of a particular year, we may always confider that or other peftilential difeafes, as prevailing at leaft three years. Rarely are great plagues of lefs duration, but often of greater. Hiftorians feldom mention die peftilence, except in the year of its greateft violence, but no plague, I will affert, ever yet in- ferred a particular city or country, without precurfers of a very malignant type. When therefore we fpeak of peftilence, as prevailing in a particular year, we are to confider the epidemic as extending to a period of three, four or five years, perhaps lo a much longer period, either in the form of pUguc, a deadly petechial fever, or other fatal difeafe. In the foregoing defcription of the difeafe under Commcdus, we notice the vulgar modes of guarding againft contagion, by fluffing the nofe and ears with aromatics—a practice that in part fubfifts at this day, altho conftant experience proves it to be ut- terly ineffectual. It appears from Herodian that a comet appeared at this peri- od, or other lingular heavenly phenomena. He fays, " Ea tempeftate ftellae per diem perpetuo apparuerant, quaedamque ex iis in longum productae medio quafi aere fufpenfae videbantur." Comets are fometimes vifible in the day time, and it is well known that many of the ancients confidered them as meteors, floating in the earth's atmofphere, as we fee in Ariftotle, Seneca and Pliny, who have difcuffed and refuted thofe opinions. See alfo Sampridius who mentions the comet and unufual darknefs, at this period. Another circumftance mentioned by Herodian deferves no- tice. He fays, that animals at this time grew out of their ufual fize, affuming an extraordinary figure and difproportioned in their parts. " Preterea animalia, genus omne, minime fuam naturam fervantia, cum figura corporis prodigiofa, turn membris haudquaquam congruentibus edebantur." This fact the writer arranges under the head of prodigies ; but numerous modern ob- fervations confirm the veracity of the hiftorian. In many plagues, t» be hereafter mentioned, myriads of unufual animals have ap- peared, and many common animals and infects have grown to an unufual fize. With this fact almoft invariably attending pef- tilence, and before the eyes of every man of fcience in well at- tefted accounts ; a fact that demonstrates a prodigioufly pefti- lential ftate of the elements, modern philofophers, phyficians and rulers have been tracing all the plagues of the earth to one or two little fpots in Egypt and the Levant—This circumftance is hardly credible ; yet is true, and indicates a lamentable de- cline of found philofophy. A flight fhock of an earthquake is mentioned incidentally by Herodian, after the plague. Speaking of the burning of a 77 temple in Rome, he fays " there had been no ftorm or clouds, but a fmall earthquake preceded the conflagration :" and he in- finuates that the building might have been fet on fire by a flafli of lightning in the night, or by an eruption of fire in the earth- quake. In 193, Canterbury in England was feverely fhaken by an earthquake. The plague prevailed in London in 211, and a comet ap- peared in the fame year. In 214, there was a moft dreadful inundation of the river Trent in England, which fpread over 20 miles of country, and deftroyed many lives. Here is prob- ably a miftake in chronology of at leaft two years—or rather a difference between different authorities. Eufebius, the learned Bifhop of Cosfaria, places die birth of Chrift two years earlier, than the common or Dionyfian Chronology. Many authors fol- low one mode of computing time and many the other ; and without the original authors, and a clofe attention to their modes of reckoning time, it is not poflible to reconcile thefe differ- ences. The uniform influence of comets in producing violent tempefts and unufual fwelling of the ocean, within a year of their appearance and after their departure, may aflift in correct- ing ancient chronology. In the year 218 two comets appeared, and a fevere froft of five months is related tp have happened in England in 220. There was a great inundation of the Tweed in 218, and a peftilence in Scotland in 222 which deftroyed 100,000 lives. In 235 a comet is noted, but I find no other phenomena men- tioned about this time, except a great death of fifh in 231, mul- titudes of which were wafhed afhore on Britain ; and an earth- quake in Wales in 232. In the reign of the Emperor Gordian, about the year 243, the earth was agitated by moft violent earthquakes ; and in 245 there was a prodigious inundation of the fea in Lincolnfhire, England, which laid under water many thoufand acres of land, which are faid not yet to be recovered, A fevere winter is men- tioned in 242. JL We have now arrived to one of the moft calamitous period recorded in hiftory—a period of mortal plagues, which com- menced about the year 250, or 252 in the reign of the Emperor Decius and coatinued fifteen or twenty years, through the ad- miniftration of Gallus and Volufian, Valerian and Gallienus. This period was ufhered in by a comet in 250, the winter of Which in England was fo fevere, that the Thames was frozen for nine weeks,—An eruption of Etna is noted under the year 253, and an earthquake in Cornwall in 251. The plague appears to have been moft fatal in Rome at two different times, during this period ; viz. in the years 252 and 262 or 3, including the year preceding and fucceeding each of thefe periods. It reached the northern parts of Europe, and in 266, Scodand had fcarcely living people enough to bury the cicad. It firft appeared in Ethiopia, on the confines of Egypt, and Ipread over all the provinces of the Roman Empire, which, fays Zonoras, were exceflively exhaufted by its deftructive ravages. Zofimus, after defcribing the devaluation occafioned by the ir- ruption of the Scythians, fays " Lues etiam peftilens in oppidis atque vicls fubfecuta, quicquid erat humani generis reliquum, abfumpfit." The plague in towns and villages followed the Scythians and devoured that part of the human race which the barbarians had fpared. Jornandes fays, the peftilence " faciem totius orbis foedavit" —defolated or disfigured the face of the whole earth.—In the reign of Gallienus, 5000 citizens of Rome perifhed daily, in 262, or the following year, a portion of this period moft diftin- guifhed for convulfions of the earth. This latter period was marked by deftructive earthquakes in Rome, Syria and other countries. In fome places the earth opened and fait water iffued. Trebellias Pollio fays, " Fright- ful earthquakes fhook Italy, Afia and Africa. For many days, f fome authors fay, three days] there was an unufual or preter- natural darknefs and a hollow rumbling noife in the earth, which opened in many places. Many cities in Afia were overwhelmed, 79 and others loft in the ocean. Peftilence followed and defolated the Roman Empire." In the Univerfal Hiftory, it is faid that this plague ravaged Capadocia and all Afia Minor, and was followed by famin, earthquakes and a great comet or meteor. Orofius remarks that " Nulla fere provincia Romana, nulla civitas, nulla domus fuit, quae non ilia generali peftilentia cor« repta atque vaftata." Scarcely was there a province of the Em- pire, a city or a houfe, which was not attacked and defolated. This paffage is worthy of notice, for it will hereafter appear, that altho the plague is ufually limited to cities, where powerful artificial or local caufes aid the general contagion, yet in fome in* fiances, the general ftate of the atmofphere has been fo peftilen* tial, as to produce plague on the moft elevated hills and falubri- ous places, in detached villages and houfes, without the leaft communication with the fick and infected. Gibbon chap. 10, has calculated that " a moiety of the hu- man fpecies" fell a prey to this frightful epidemic. Cedrenus page 211 fays this difeafe began in autumn and ended at the riling of the dog-ftar ; or beginning of Auguft. The ftate of the air, during this peftilence, was uncommonly impure. The defcription of it by Eufebius, in a philofophical view, deferves notice. " Quando, inquit, aer ifte pravis undi- qae evaporationibus turbatus, ferenus reddetur ? Tales enim e% terra fumigationibus, c mari venti, e fluminibus aurae, e portubus pxhalationes fpirant, ut veluti ros quidam tabidus e cadaveribul putridis, cunetis fubjacientibus elementis inferatur." Magdeburgh. Cent. 3. p. 31. This is a remarkable inftance of a ftate of air fo highly cor- rupt, as to form on objects a mould or coat, like a turbid dew, from dead bodies ros tabidus—a ftate of air which the author af- cribes to vapor from the rivers and the earth—The account ;. analogous to what is related of other peftilential periods, and the fact denotes an utter derangement in the healthful qualities of ait a,nd water.—Cedrenus compares this dew to the gore of dead perfons. " Ros faniei mortuorum fimilis apparebat." Page hi, 8o In the Traite de la Pefte, I find the following defcription of the fymptoms of this malady, from St. Cyprian—dejection of mind, exhauftion of ftrength, inceffant involuntary evacuations, as in certain paralifes, violent fever of the bowels, mouth infla- med, ftomach fwelled, eyes fparkling. The difeafe deftroyed the feet, the hands, the fight, the hearing and organs of gen- eration. Aurelius Victor fays of this plague " Simulque Romam pef- tilentia graffabatur, quae fiepe curis gravioribus atque animi def- peratione oritur." The plague fpread, which often arifes from the more diftrefling cares and defpair. This defcribes the mife- rable ftate of mankind, at that period; but anxiety and defpair do not produce the plague, except during the prevalence of a pefti- lential ftate of air. There muft be a ftrong predifpofition in the body, or an imbecillity in the powers of animal life previoufly induced ; or the utmoft preffure of grief will never occafion a plague. But at the time when general caufes have impaired the vigor of the animal principles, flight caufes will often induce fever and deftroy life. The practical inferences from this fact are extremely important to mankind. The articles in this account of peftilence which deferve par- ticular notice, are the introduction of the period by a comet and an eruption of Etna—the agitations of the earth by fubterranean fire—the preternatural darknefs of three days, a phenomenon not unufual at fuch times and eafily accounted for, on the fuppofition of the extrication of a great quantity of fubterranean vapor—. the peftiferous ftate of air which covered objects with mould and-; c ormption—and which generated plague in every village and al- moft every houfe. See Zofimus in Gall. lib. i. fee 26. 37, 46. Zonoras lib. 12. Trebellius Pollio ia Gall. Jornandes. Hift. Auguft. 1098.- "' F.liop. lib. 9. Baron, vol.2. 496. Aurel. Victor.Epit. . Magdeburgh. Cent. 3. 31. Near theclofe of this period, about the year 272, there was an eruption of Vefuvius. At the fame time, a fevere famin raged in England. Five or fix years later, a fevere famin prevailed^ over the world. • " Fames ingens per totum orbem graffata eft." Zoiimus. 8i It is proper here to notice an inaccuracy of the celebrated New- ton, in his Differtations on the prophecies, on the 6th chapter of Revelations, in which he fays, " In the reign of Probus alfo there was a great famin throughout the world—an ufual confe- quence of famin is peftilence.—This peftilence according to Zo* noras, arifing from Ethiopia, while Gallus and Volufian were Emperors, pervaded all the Roman provinces for fifteen years." But Probus began to reign in the year 276, whereas the pefti- lence broke out in Ethiopia under Decius or Gallus and Volu- fian, about A. D. 252 according to Zonoras, but according to other authors, two or three years earlier. Therefore the pefti- lence under Gallus, could not be a confequence of a famin under Probus, which was 25 years later than the plague afcribed to it. Thefe remarks are neceffary to correct that paffage of Newton, and they are ufeful in correcting the common notion, that the plague is ufually occafioned by famin. The idea is probably un- philofophical; but is certainly contrary to fact. Famin often goes before the plague, and as often follows it. But fome of the moft difaftrous periods of the plague, have originated during the greatefl abundance of provifions.—Such was the fact in England, in 448, and in 1347, as will be hereafter related. The great er- ror of hiftorians and phyficians has been, that obferving famin and peftilence often cotemporary, and the caufe of the plague not being obvious to the fenfes, they have taken famin to be the caufe. Whereas it will appear on careful inveftigation, that fam- in is an eflia of the fame caufe which produces the plague among men. The dearth of provifions, during this formidable epidemic, is the effect of a.peflilence In vegetation ; that is, a failure in the principles of vegetable life, which proceeds from the fame de- rangement of the feafons, or defect in the properties of air and water, which caufes the plague among men.—Famin often aug- ments peftilence, and modifies the fymptoms of the difeafe ; but in a health j ftate of the elements of life, air and water, famip will not produce the plague. This may be otemonftrated by mul- tiplied inftances of feamen, ftarving on the ocean, who often per- jfn by hunger, without difeafe, or if they had difeafes in conf;- L Se- quence of mere hunger, nothing like the plague has ever been of the number. I cannot help noticing alfo the obfjrvations of Mr. Gibbon on the calamities of this period. He fays, " Our habits of thinking fo fondly connect the order of the univerfe with the fate of man, that this gloomy period of hiftory has been decora- ted with inundations, earthquakes, uncommon meteors, preter- natural darknefs, and a crowd of prodigies faitlous or exagge- rated." See vol. i. ch. 10. If the original writers who have related the facts above men- tioned, had been as fond of decorations, as this author, we might well have diftrufted their accounts of unufual occurrences. Had this elegant writer taken due pains to inform himfelf of the truth, before he had indulged fuch reflections on the moft cred- ible hiftorians, he would have found fimilar phenomena to have attended the fame calamity, peftilence, in every age from that period to the prefent, aad many of them if not all, during his own life, if not within his own obfervation. He goes on to obferve that " famin is almoft always followed by epidemical difeafes." This point will be afterwards confidered. He fays alfo that the plague at this period " raged from 250 to 265, without interruption, in every province, every city and almoft every family of the Roman Empire." The words without interruption, were probably inferted for the fake of decoration. They are not authorized by the original writers ; and cannot poflibjy be true, for an uninterrupted plague in a city or country, would foon leave it without an inhabitant. The truth is, it feldom raged, more than fix or eight months, in the fame place, at one time. It feized this town, one year, and that, the next, as we obferve in modern times, through the whole period.* The more I examin the original writers, from whom Gibbon derived his materials, the lefs confidence I place in his reprefent- ations of events. He appears to be a partial hiftorian and a fuperficia! philofopher. * The words of Zonoras, per quindeccm continuos. anuos, are tq be underftood as above explained. «3 In 280 a comet, and in 282 an earthquake in England. In the year 289 was vifible a large comet, and in 290 the Winter in England was very fevere, all the rivers being clofed For fix weeks. Bufiris and Coptis, two cities of Egypt, were overthrown by an earthquake. In 292 famin, peftilence and drouth prevailed—the bodies of men were covered with carbun- cles and ulcers. Cedrenus. Worcefter in England was almoft ruined by an earthquake in 287. » Short, vol. 2. In 298 alfo appeared a comet and earthquakes foon followed, which in Syria, deftroyed feveral thoufand lives. Magdeburgh, Cent. 4. p. 1434- Earthquakes were experienced in Conftantinople in 309 & 3 iO. In the year 311, the ufual rains of winter failed in Italy, famin followed and then peftilence. Baronius, vol. 3. p. 69, defcribes it as a new difeafe of foreign origin, which, in con- fequence of exceflive heat, produced the anthrax or carbun- cle over the whole body, which expofed the patient to mortifi- cation. It fell upon the eyes with great feverity, rendered ma- ny perfons blind, and deftroyed the lives of great multitudes of all ages. The reader will remark that this diftemper was not of domeftic origin ! This is a ftale cuftom of -afcribing all evils to foreign fources. It is related that Cyprus, about this period, fuffered a drouth of thirty-fix years in confequence of which it was nearly difpeopled. Under the chronological tables, I find a famin mentioned to have deftroyed in England and Wales, forty thoufand lives in the year 310 ; and in the following year a violent earthquake injured London. A comet is noted in 321, and a univerfal famin in Britain in 325. In the year 335, appeared a comet of great magnitude, and as it was about two years before the death of Conftantine the Great, fuperftition held it to be the omen of that event. Tn 336 Syria and Celicia were laid wafte by peftileatial dif- u cafes. There was an inundation of the Tweed, the fcn:e ycr.f. Etrop. lib. 10. Orofius, lib. 7. Magdeb. Cent. 4. 1442. I have not found any particular account of the duration or extent of this calamity. But it appears that this period, like that in the time of Thucydides, was followed by moft deftruc- tive earthquakes in 340, which overwhelmed or injured many cities of the eaft. A comet marked this period in 339. Baron vol. 3, p 536. A fnoW of 15 feet depth in England is recorded under the year 341. In 358 happened a moft tremendous fhock of an earthquake, Which buried in ruins the greateft part of Nicomedi.:. The fhock happened foon after day-break in the morning, 1 ith Kal. Sept. and was preceded by a collection of vapor or clouds, that covered the city with impenetrable darknefs, fo that the eye could not difcera the neareft objects. This was foon fucceeded by flafhes of lightning and moft violent winds and tornadoes, which carried buildings to the adjacent hills. The fcene was clofed by a fhock of the earth which demolifhed a large portion of the city. Authors relate that this earthquake levelled 150 cities. Short indeed was the refpite which Afia Minor enjoyed. In 362, the remains of Nicomedia were deftroyed, part of Nice was overturned, Jerufalem was fhaken and other parts of the world did not efcape. This was the year alfo in which Julian attempted to rebuild Jerufalem, when fire burfting from the earth, deftroyed the works and rendered the place inacceflible. This event has been afcribed to a preternatural influence ; but is a common phenomenon in Italy, Afia Minor, and in all countries fubject to earthquakes ; and as it happened when the neighboring countries were laid wafte by the explofion of fubter- ranean fire, there is no neceflity for reforting to fupernatural caufes, to account for the phenomenon. During thefe agitations of the earth, the fea receding left its bed, a highway for paffengers. Inundations fucceeded, and drouth, famin and peftilence walked in the train of public ca- lamities. «5 In the following years, the earthquakes were repeated and Baronius afferts that the whole world was fhaken ; the fhores of the fea were in fome places changed ; fome places funk, and in others the waters rofe and carried veffels over the tops of houfes. Authors place the deftruction of Nice in 367, and of other cities in 368 or 372. The deftruction of Nicomedia was preceded by a fever© drouth—a common event, that a violent explofion of fire from the bowels of the earth, is preceded, fome weeks or months, by a total exhauftion of water by evaporation. In the midft of thefe convulfions, appeared a comet in 363 or 4, and a meteor or globe of fire in 363. A hard winter of 14 weeks duration in England is mention- ed under the year 359, the year following the deftruction of Nicomedia, and the fevere drouth. This is a ufual event. A fingular light of great extent appeared in the heavens, in the year preceeding. The whole reign of Conftantius was diftinguifhed for deftruc- tive earthquakes, and the early writers of ecclefiaftical hiftory " make no doubt that God, by thefe judgments, manifefted his difpleafure at the prevalence of the Arian blafphemies." A dreadful famin clofed this period. It was during the early part of this period, in 359, that the plague broke out in Amida, a city of Perfia, when befieged by Sapor, and from which, when taken, Am. Marcellinus very narrowly efcaped. SeeBaror. vol. 4. 121,188, 209; vol. 3. 776. Am. MarceL lib. 22 and 25. P. Mexia Hift. Emp. p. 339. Eutrop. lib. 11. Niceph. lib. 9 and 10. Magdeb. Cent. 4. c. 13. Ech. Rom. Hift. vol. 3. 116. Aurelius Victor, Epit. Julian. Juft before the death of Valentinian I. appeared a comet, in the year 375. Zofimus mentions a hard winter at that time, extending to an unufual length. Another author mentions a fe- vere drouth about the fame time. Crete, Peloponnefus and Greece in general were agitated by earthquakes and fome towns were demolifhed.* In Wales 43,000 died of the plague. Echard's Rom. Hift. vol. 3. 156. Zofimus lib. 4. Magdeburgh Cent. 4. ca. 13. Am. MarceL • Gibbon chap. 26 ha» well defcribed the earthquakes of 365, but 86 The following year was marked with famin, and univerfal pfeftilence among men and cattle. So fevere was the famin in Phrygia that the inhabitants abandoned the country. Baron, vol. 4. 380. A comet appeared in 383, and the plague raged in Rome and in Syria in 383 and 4.—This'ftar however is defcribed by Ni- Cephorus and others, as of a fingular figure, refembling a burn. ing column ; its motions differed from thofe of other ftars^it was vifiblc 30 days. Niceph. lib. 12. Magdeb Cent. 4. ca. 13. Abbut the fame time, the Nile rofe to fuch an alarming height as to threaten Alexandria and Lybia with an inundation. Sozomen, lib. 7. 20. Magd. Ibm. Juft before the death of Theodofius, about the year 394 or 5, happened dreadful earthquakes, ftorms, rain and unufual dark- nefs. The appearance of the fiery column and the inundation are placed by fome authors under the year 394. The Magdeburgh Hiftory from Profper's Chronicon, places it under the fixth year of Gratian, which is alledged to be the year of Chrift 393* But Gratian was killed about the year 383. There is therefore a miftake as to the era of this phenomenon, which, as defcribed by authors of credit, was one of the moft fingular that was ever ex- hibited to the people of this globe. Niceph. lib. 12. 37. Magd. vol. 2. 1452 and 5. About this period, fwarms of locufts covered the land of Ju- dea ; and being driven by the winds into the fea and wafhed on the fhore of Paleftine, by Gaza, Afcalon and Azotus, they fil- led the atmofphere with a fetid effluvia, which occafioned pefti- lence among men and cattle. Magdeburgh from Hieronymus, vol. 2. p. 1455. In 396 Conftantinople fuftained a violent fhock of an earth- quake, during which the heavens appeared to be in a flame. Functius places thefe events under the year 400, and he is prob- ably correct. Baron, vol 4. 20. P. Diac. lib. 13. by miftake quotes Zofimus lib. 4. p. 221 ; whereas the latter author, in this pafiage, defcribes the earthquakes of 375. s-7 We are now arrived at another lingular and drftrefling period of the hiftory of man. . In the year 400, under the adminiftrfu tion of Arcadius and Honorius, a comet appeared of a prodi- gious fize and horrible afpect. Its immenfe coma feemed to fweep the earth, and Baronius, the pious author of Ecclefiaftical An- nals, remarks, that many of the Gentiles were terrified into chriftian baptifm and converfion. During its approach or appearance, happened one of the moft fevere winters on record. ' The Euxine Sea was covered with ice for 20 days. A drouth is mentioned under the fame period, which was fo fevere that the heavens were like brafs. Unfortu- nately hiftorians have often neglected to arrange thefe phenomena indue order, throwing them into a general defcription, The fame period was marked by deluges of rain, and from the order of narration, it appears that the raxnspreceded the hard win- ter of the year 40Q. The rivers were fo fwelled as to prevent the imperial generals from palling into the eaft to attack Sardis,—« Severe earthquakes occurred in the fame year. About the year 407 or 8, near the clofe of the reign of Area* dius, a celeftial phenomenon of a, fingular fpecies prefented itfelf to the view of an aftoniftied world. It was called a comet, but did not refemble one of the ordinary figure. It refembled a cone or pillar, but had not the appearance of a ftar, fo much as of the flame of a lamp, Its motion was not regular—it began to move from the point of the heavens where the fun riles at the equinox- es, and pafling the tail of Urfa, proceeded to the weft. It meafured the heavens—its vertex, at fome times, extended to a great length ; at others, was contracted into die figure of a cone. After being vifible for four months, it difappeared. This is the defcription of it, nearly in the words of Nicephorus. Me- teors were obferved at the fame period. Accompanying and following thefe phenomena, were fome of the moft diftrefling calamities. Violent earthquakes levelled' cit- ies—inuBdatioas of rivers and the fea, followed by intolerable cold ftorms of hail, and a drouth that blafted vegetation, by which means multitudes of people perifhed. Peftilence raged in every quarter, and famin fo fevere, that the populace deman- 88 ded that human flefh fhould be fold in market. Paleftine was de voured by locufts. Nicephorus has employed a chapter to defcribe the phyfical evils, and the mifcries of man, in this fingular period. He de- clares that almoft all Europe perifhed.—" pafa deoleto e Europe." and no fmall part of Afia and Africa. Niceph. lib. 13. ca. 6 and 36. Baron, vol. 5. 20, 114, 176, 294. Zofimus lib. 5. Magd. Cent. 5. ca. 13. Ech. vol 3. 254. In 418 appeared a comet; in 419 feveral cities of Afia were overturned by an earthquake, and in 420 there was an eruption of Etna. There was alfo an inundation of the fea in Hampfhire, in England, in 419. Famin and peftilence prevailed alfo in this period.—A great ftorm of hail is mentioned under the year 418, and deep fnow. The next period of general peftilence commenced in the reign of Theodofius the younger, about the year 445—or a year or two earlier. A cornet in 442, ufhered in a fevere winter, in 443, the fnow fell to fuch a depth and continued fo long in Illyri- cum, that multitudes of men, women and children perifhed. The year preceding, the Huns had ravaged the country and deftroyed, the provifions, which added to the public calamities. An irrup- tion of the Sea in North and South Wales, 441, preceded the firft comet, a fecond comet appeared in 444. In 445, fevere famin and plaguetHftrefTed Conftantinople, and peftilence appear- ed in all parts of the world. In 446, Sept. 17, occured a tre- mendous earthquake, which demolifhed the greateft part of thp walls of Conftantinople, with fifty feven towers. The fhocks continued unremittingly for fix moHths, and extended to a great part of the globe. Many cities were overthrown, the earth, j.n fome places, was thrown into large hills ; in others, it opened and fwallowed up whole towns. Iflands difappeared and were loft in the ocean : the fea receding, left fhips on dry land, fprings of water were dried up and new fountains appeared, and in this violent concuflion of the elements perifhed innumerable multi- tudes of fifh. The peftilence attending, and which rarely fails to attend fuch agitations of the earth, was univerfal and of feveral years dura- tion. In this period, the plague in England was correfpond- r-.nt to the terrible operations of fubterranean fire. In 448 or & it carried off incredible numbers of people, fo that the living could fcarcely bury the dead.—And it muft not be omitted that the plague was preceded by the greateft abundance of provifions. This was in the reign of Vortigern, and in time of peace. Niceph. lib. 14. ca. 46. Beda. Ec. Hift. ji, 52. Baro- nius, vol. 6. p. 30, 36, 37, 38. Echard. vol. 3. 331. Magdeb. Cent. 5. ca. 13. An important fact here occurs. In 446, the Picts and Scots had overrun and defolated England, fo as to occafion a dearth of provifions. But this famin produced no peftilential difeafe. It is particularly noticed by the hiftorian, that the plague did not occur, till a year of great plenty had intervened. This is one ftrong proof among others, that famin is not the caufe of plague j oat often accompanies, and fometimes increafes the difeafe. It often happens that, during extraordinary agitations of the earth, the elements of vegetable life appear to be defective. The fame caufe which affects human health, feems to prevent the growth or vitiate the pabulum of vegetables.* The clofe of this period was peculiarly diftreffing in Italy, Phrygia, Cappadocia and Galatia, where the famin compelled parents to devour their own children. The peftilence made great havoc, at the fame time, and no remedy or alleviation could be found. The body was -univerfally inflamed and cover- ed with tumors. The difeafe deftroyed the eyes. A cough fuc? ceeded the eruption, and ended life on the third day. Niceph. lib. 15 ca. 10. This was in the beginning of the adminiftration of the Em- peror Marcian, which commenced in 450, in which year anoth- er cornet was difplayed in the heavens and a fingular light or ' Gcrcral defcriptions are feldom correct. I have already takennotice nf the miftakss committed by Newton and Gibbon, whofe general de- fcriptions lead, in the inftances mentioned, to falfe conclufions. A hmilar miftake occurs in Henry's excellent Hiftory of Britain, vol. 1. c:\. 1. concerning the calamities of the Britons, in the period under confideration. The author fays, " the neglect of agriculture naturally produced a famin, which was followed by a peftilence."—Thefe facts are not correctly ftatcd. The incurfions of the Picts and Scots had occafioned the neglect of culture and a famin ; but this famin was fol- lowed by plentiful crops, which were fucceeded ky peftilence. M 90 flame, a fevere drouth " ingens ficcitas," afflicted the. earth, and the calamities of this period continued for feveral years. It muft be remarked here that Funftius has placed this comet and the beginning of Marcian's reign, in 454. Such differ- ences in chronology cannot fail to embarrafs an inquiry like the prefent, the refults of which depend much on correctnefs of dates. Nicephorus and Evagrius give a particular account of an earthquake which laid great part of Antioch in ruins in the fec- ond year of the Emperor Leo, which was A. D. 458. A comet is noted under the preceding year. But they fay further,' that this event took place 347 complete years after the deftruc- tion of the city in the reign of Trajan, which was in 117. Now 347 years added to this number, give 464, for the year of the laft cataftrophe. Niceph. lib. 15. 20. Evag. lib. 2. 12 and 14. In the 311 th Olympiad, which comprehends the years from 465 to 468 inclufive, appeared a comet. Whether the de- ftruction of Antioch was in 458 or 464, the extent of the fhock, through Thrace, Hellefpont and the Grecian ifles, to« gether with the deluges of rain which are faid to have fwept away whole towns in Bithynia, leave no room to queftion the ap- proximation of a comet at or near the time. Byzantine Hift. vol. 15. Evag. lib. 2. 14. This latter period was diftinguifhed for peftilence which raged in Rome, about the acceffion of Anthemius to the empire, and according to Baronius in the year 467. Vol.6. 281. In thefollowing year, a number of houfes were overthrown by an earthquake at Vienna. Of the extent and duration of the peftilence, I have no particular defcription. A great eruption of Vefuvius is mentioned in 472, and a fevere winter of four months duration, in 473 with deep fnow.—The plague fucceed- ed in Rome. In the year 480 Conftantinople again fuffered great damage by an earthquake, which demolifhed a great number of buildings. In 480 or the following year another comet was vifible ; or probably two years later. In 484 occurred a drouth moft terri- 9* ble and diftrefling—not a vine nor an olive branch retained its verdare—the earth was pale and defolate, and the fun affumed a melancholy face. Africa was almoft abandoned, in confequence of this event and an attending plague. Baron, vol. 6. $<3, 426and 7. Baronius places the earthquake at Conftantinople in 477, but others place it in 480, which is moft probably correct. The dif- ference in the chronology of different authors, who relate the events of thefe early ages, is feldom lefs than two, three and four years.—The plague infefted Scotland in 480. In 494 an earthquake overturned Laodicea, Hierapolis and Tripoli. According to Functors, this event was in 496. Magdeb. vol. 3. Cent. 6. ca. 13. In 499 appeared a comet, which was foon followed by an earthquake which deftroyed Neo Cefarea, in Pontus, and an eruption of Vefuvius laid wafte all the adjacent country. Zonoras lib. 3. Baron, vol. 6. 541. Magd. Cent. 6. ca. 13. p. 789. A comet is noted in 502, and a fevere winter in 507, but I have no account of any public calamity, attending either of thefe phenomena, except a peftilence among men and cattle in Scot- land, in 502. In 517 is recorded a five year's drouth in Paleftine. Encyclop. Chronol. In 518a comet; and in Dardania, now Masfia, a feries of earthquakes demolifhed twenty-four caftles, divided mountains and in one place opened a fiffure of thirty paces in length and twelve in breadth. Baronius vol. 6. 702. In 519 two cities in Cilicia were overthrown ; Ediffa was in- undated and part of its buildings and inhabitants overwhelmed. Zonoras, Tom. 3. Magd. Cent. 6. p. 791. Evagrius places the inundation at Ediffa, in the following pe- riod, after the deftruction of Antioch ; and as the hiftorians do not always fpecify the year in which a particular event took place, I am inclined to believe the account of Evagrius. o Lib. 4. ca. 8. In the 7th year of the Emperor Juftin, A. D. 525, appeared a comet, and the fame year Antioch was again overwhelmed in 92 ruin by an earthquake. Some authors relate that 300,000 pe?» fons perifhed in this cataftrophe, and among them Euphiafius, the bifhop.—This event happened on the 29th of May, about 12 o'clock. A conflagration followed and confumed what was left of the city. In the fame fhocks, Dyrrachium, now Durazzo, the Epidaurus of high antiquity, Corinth and other cities were greatly injured. Baronius vol. 7. 109, no, in. Niceph.lib. 7. 3. Evag. lib. 4. Zonoras Tom. 3. A fevere winter happened the fame year. In 528 Antioch was again fhaken and fuffered confiderable injury. An inundation of the Humber in England is noted about this time. In 531 appeared the refplendent comet, whofe revolution is fixed at 575 years, fuppofed to be the fame which was vifible in the year before Chrift 44, after the death of Julius Cefar. Thi3 was the fifth year of the reign of Juftinian. Famin and a flight plague prevailed in Wales. At this period Gibbon commences his lively, but unphilofoph- ical defcription of the formidable and deftructive calamities, which afflicted the whole earth in the 6th century. See his hif* tory, vol. 4. ch. 43. Not long after the approach of the comet in 531, the fun af- fumed a pale color, and fhone with a feeble light. In a tranfla- tion of Cedrenus, this phenomenon is thus defcribed. " Toto anno eo, fol lunae inftar, fine radiis, lucem triftem praebuit, ple- rumque defectum patienti fimilis." During the whole year, the fun gave a gloomy light, like the moon, and appeared as if eclip- fed. Byzantine Hift. 3. 293. Prpcop. de bell. Vandal, lib. 4. It is remarkable that tradition has preferved a faint account of a fimilar phenomenon, during the approach of the fame comet, at the time of the Ogygean inundation, before Chrift 1767. It is faid, that the planet Venus changed her color, fize and figure* An account is preferved in tradition, of a phenomenon of the fame nature, during the approach of the fame ftar, in a fubfe- quent revolution. Gibbon in the chapter above cited.__Pliny, as I have already remarked, mentions a fimilar phenomenon* 93 about the time the fame comet appeared, foon after the death of Julius Cefar. The appearance, in the period under confideration, is a well authenticated fact, and witneffes a fingular change in the prop- erties, and reflecting powers of the atmofphere, or denotes an effential alteration in the face of the fun, which is improbable* In either cafe, it feemed a prelude to the moft dreadful calami- ties, famin, earthquakes, and peftilence. I am not without fuf- picions that Europe might have been overfpread with a vapor like that in 1783, during the eruption of Heckla. In 534 is recorded oneof the moft diftreffingfamins,that ever afflicted the earth ; it continued many years, and deftroyed mul- titudes of the human race. Pompeiopolis was this year over- whelmed in ruin by an earthquake* and great numbers of its inhabitants perifhed. Paul. Diac.lib. 16. About this period, Vefuvius began to utter hollow rumbling noifes, the precurfors of an eruption. Baron, vol. 7. 218. Procop. de Bell. Goth. Magdeb. Cent. 6. p. 793. Excepting a flight plague in Wales—no peftilence is mention- ed by the authors I have confulted, until the year 542. But the famin, in great feverity, had raged eight or nine years be- fore—a proof that fomething more than famin is neceffary to generate the plague. In 539 appeared another comet, and the famin now raged with double horror. The country of Italy had been ^ravaged, the year before by the Goths and Burgundians, and the lands left untilled. This might have contributed towards the dearth which followed. It is recorded that many perfons fed on hu- man flefh, fome diftricts of Italy were deferted, 50,000 people perifhed in Picenum, and greater numbers in other diftricts. The bodies of the famiflied people became thin and pale ; the fkin was hardened and dry like leather, and clave to the bones; the flefh affumed a dark appearance like charcoal, the counte- nance was fenfelcfs and ftern, the bile redundant. Procop. de Bell. Goth. lib. r. Among thefe frightful effects of hunger, no plague yet ap- 94 ptars—a circumftance that the philofopher fhould not pafs unno- ticed. The account which Baronius gives of this famin, is, perhaps more philofophical and deferves notice. He fays, the crops failed, corn ripened prematurely, and was thin ; in fome places, it was not harvefted, and that which was gathered, was. defi- cient in nourifhment. Thofe who fubfiftcd upon it became pale, and were afflicted with bile. The body loft its heat and vigor, the fkin was dried, the countenance ftupid, diftorted and ghaft- ly, the liver turned black. Many perifhed by hunger; many betook themfelves to the fields to feed on vegetables, and being too feeble to pull them, lay down and gnawed them off with their teeth. Baronius, lib. 7. 326. This is the moft probable account of the famin. Repeated inftances are on record, which evidendy mark a peftilential ftate of the elements, as fatal to vegetable, as to animal life. In many periods of the world, there has been a univerfal defect in the powers of vegetation. This phenomenon in the vegetable kingdom is cotemporary, or nearly fo, with peftilence among men ; and fuperficial obfervers have afcribed the plague to a prior or cotemporary famin. But an accurate furvey of facts, will probably convince any candid enquirer after truth, of the fallacy of this opinion. It will be made apparent that famin and pefti- lence are equally the effeas of fome general caufe ; a temparary derangement of the regular operations of nature. In the prefent inftance, the famin could notbeexclufively and immediately the caufe of the formidable plague that afterwards affailed mankind, for it was moft fevere in 539, and the next year the crops were good. But the plague did not break out till 542, at leaft I can find no account of any peftilence, during the Famin. An eruption of Vefuvius is noted under the year 532, the year after the appearance of the great comet.—It is probable that the palenefs of the fun was owing to a vapor from fome volcanic eruption, as in 1783 ; and it is remarkable that both of thefe ^periods alike produced famin from defective vegetation. 95 During the remaining part of this century, a feries of moft calamitous events afflicted th» earth. A mountain in Rhodes burft open, and a part of it rolled down upon the inhabitants be- low. Many places fuffered by inundations, one of which over- whelmed the borders of Thrace for an extent of four miles. In the year 543, the whole earth was fhaken by earthquakes. This was the year in which the plague broke out in Conftantino- ple ; but it commenced in Egypt, the preceding year.-—In 543 there was a dearth of corn, wine and oil. The plague again ravaged Conftantinople in 547. In 545 there was an inundation of the Thracian fea, and a fevere winter. A terrible dyfentery in France in 548. See Cedrenus, and Paulus Diac. lib. 16. In 550 an earthquake convulfed Syria and Paleftine; and Greece in 551. In 553 appeared a fingular meteor in the north and weft, which was preceded by a winter fo fevere that wild beafts and fowls might be taken by the hand. Inundations marked this period, Conftantinople was fhaken 40 days in 554, Paul. Diac. Madeburgh Cent. 6, ca. 13. In 557 Conftantinople was almoft laid in ruins by an earth- quake. In 558 a comet appeared, a fevere winter followed and univerfal plague, efpecially in Conftantinople, where the living could not bury the dead. This year the Danube was cov- ered with ice. In 560 an earthquake deftroyed Berytus and injured Cos, Tripoli, and Balbiis. An exceflive drouth in 562, andaplagus began which fpread over the whole world. There was a dark day in the fame year. The year 565 was diftinguifhed fcr a calamitous plague, in France, Germany and Italy, which Baronius calls " vehemens peftis inguinaria." Vol. 7. 547- In 580 Antioch was again laid in ruins by an earthquake, and a fhock was felt in Scotland. The plague again prevailed, from that year to 583, in Gaul and Germany and other coun- tries. In 587 it ravaged Italy. Earthquakes attended this pe* riod. 96 In 590 appeared a comet; an inundation, from deluges 01 rain, overfpread Rome, covering the walls of the city, and lodging innumerable ferpents on the plains. In the next fummer, happened the fevereft drouth ever known ; it lafted from Janu- ary to September; and the moft deadly plague ravaged all Italy. In this peftilence, died Pope Pelagius. This is a general fketch of the phenomena recorded of the period under confideration. Of the univerfal and deftructive plagues which difpeopled the world in the reign of Juftinian I. and the fucceeding age we have accurate accounts by cotemporary hiftorians: From two of which, Procopius and Evagrius, I fhall tranfcribe the particulars. Procopius relates, " That this peftilence, which almoft de- ftroyed the human race, and for which no caufe could be aflign- ed but the will of God, did not rage in one part of the world only, nor in one feafon of the year. It ravaged the whole world, feizing all defcriptions of people, without regard to dif- ferent conftitutions, habits or ages; and without regard to their places of refidence, their modes of fubfiftence or their different purfuits. Some were feized in winter; fome in fummer j others in other feafons of the year. It firft appeared in Pelufiura in Egypt and thence fpread weft- ward to Alexandria and all parts of Egypt j eaftward towards Paleftine, and extended to all parts of the world, laying wafte iflands, caves, mountains, and all places where men dwelt. If it paffed by a particular country at firft, or fllghtly affeaed it, it foon returned upon it with the fame defolating rage which other places had experienced.—It began in maritime towns and fpread to the interior country. It feized Conftantinople in the fpring of 543- Moft perfons were feized fuddenly without any premonition, nor was there any change of color or fenfe of heat} for until evening the fever was fo flight that the patient was not ill, nor did the phyfician, from the pulfe, apprehend danger. But in fome cafes, the fame day ; in others, the next ; in others, at a later period, a bubo arofe, either in the groin, the arm pits, or 97 near the ear, or in fome other part. All patients alike had theft fymptoms. Some were feized with drowfinefs and flumbering ; others with furious diffraction. The flumberers forgot all things'—fome would eat if defired ; others were neglected and ftarved. Neither phyfician nor attendant caught the diftemper by con« tact of the fick or dead; and many, encouraged by their won- derful efcape, applied themfelves with afliduity to the care of the fick and the burial of the deceafed. Many were feized, they knew not from what caufe, and fud- denly died. Some who were given over by phyficians unexpect- edly recovered ; others who appeared to be in no danger fpeed- ily expired. Many died for want of relief ; others recovered with®ut affiftance. No caufe of the difeafe could be devifed by human reafon—no means of prevention or cure. To fome, bathing was beneficial; to others, injurious. Many leaped into water and the fea—In many the bubo, without fleep or delirium, turned into a gangrene, and thefe died with excruciating torture. The phyficians opened the bodies of fome, and found within the fores huge carbuncles. Thofe whofe bodies were fpotted with black pimples, of the fize of a lentil, lived not a day. Thofe who had running fores efcaped, and thefe were the moft certain figns of recovery. Some had their thighs withered $ others loft the ufe of their tongu«s. To women with child, the difeafe was certain death. This difeafe in Conftantinople lafted four months, raging three months with extreme mortality. In the beginning, few died more than ufual ; but the difeafe gradually increafed, till it fwept off 10,000 perfons in a day." Procopius calls it arrogance to pretend to aflign the natural caufes of this peftilence, declaring them to be undifcoverable. Perfic. lib. 2. ca. %%. Authors mention the early effects of this difeafe on the brain j the patients, on the firft attack, faw phantoms of evil fpirits, which made them imagine themfelves fmitten by fome perfon. Evagrius, who felt the effeas of the fame difeafe himfelf and N loft many of his family by it, has enumerated fo many fingular circumftances, that I fhall offer the reader a tranflation of his account. When I fay, the fame difeafe, I refer however to a fubfequent epidemic. Procopius, as an eye witnefs, defcribed the peftilence of 543 in Conftantinople. It did not continue inceffantly to rage in every place, for this would have foon left the earth without an inhabitant; but after an interval of a few years, it returned and revifited the fame places. The plague defcribed by Evagrius was many years fubfequent to that men- tioned by Procopius. He wrote about the year 594. His de- fcriptions however are general. See Hift. Ecclef. lib. 4. ca. 29. " I will now defcribe the plague, which has prevailed in thefe times, and already raged fifty-two years, a thing never before known, and has already depopulated the world. Two years after the taking of Antioch by the Perfians,* a peftilential dif- eafe began to prevail, in fome refpects refembling that which Thucydides has defcribed, in other refpects different. If had its origin in Ethiopia, according to common report, and fpread over the whole world, falling on different places by turns, and fparing none ef the human race. Some cities were fo feverely affailed by this difeafe, that they •were left without an inhabitant. Some diftricts however were more flightly affected. The peftilence did not always begin its attacks at the fame feafon of the year, nor ceafe to rage, in all places in the fame manner. In fome places it broke out in the midft of winter ; in others, in the fpring; in fome, it began in fummer; in others, in autumn ; and in fome cities, it attacked certain parts of the town, and left others untouched. Very often we might obferve, particular families all perifhed, in a city where the difeafe did not prevail, as an epidemic. Li fome places, one or two families only perifhed, while the reft of the city efcaped. But we obferved particularly that the families which efcaped, the firft year, experienced the fame calamity in the year fucceeding. But what above all appeared ih-.gi-.lar and furprifing was, that * Under Chofroes A. D.54?. 99 the inhabitants of infected places, removing their refidence to places, where the difeafe had not appeared, or did not prevail, were the only perfons who fell victims to the plague, in the cities which were not infected. And thefe effects were particularly obfervable, both in cities and in other places, in the cycles of the Indialons.* Efpecially in the fecond year of each indiction, was the plague extremely mortal. Of this I am myfelf a wit- cefs, for it may not be improper, when the occafion feems to require it, to interweave into this hiftory what concerns myfelf. At the commencement of tlm calamity, I was feized with the inguinal plague ; and in the difeafes, which have at different times prevailed, I have loft many of my children, ray wife and great numbers of my kindred, of my fervants and laborers: the cycles of indiction parcelling out my calamities among themfelves. At the time of writing this account, the difeafe had already invaded Antioch the fourth time; the fourth cycle of indiction had paffed, after the firft invafion of this difeafe, when I loft a daughter, and her fon. This difeafe was a compound of various others. For in fome perfons, feizing the head, it rendered the eyes fanguineous and the face tumid : Then falling upon the throat, foon put aa end to life in all that were thus feized. Some were afflicted by difcharges from the bowels. In others an abfeefs formed in the groin, a raging fever followed, and the fecond or third day, the patient died, with his body and his mind apparently found, as tho they had not felt difeafe. Some were feized with delir- ium and expired- Carbuncles alfo arifing on the body extin- guifhed the lives of many. Others recovered once and again, and afterwards died of the fame difeafe. The modes of contracting the difeafe were various and all cal- culation was baffled. Some perifhed by once entering infected houfes, or remaining in them—fome by only touching the fick. Some contracted the difeafe in open market. Others, who fled from the infected places, remained fafe, while they commu- * The cycle of "mdiclhn was a period of 15 years, at the end of 'which the Romans paid a certain tax to the Emperor?. 100 nicated tlie difeafe to others who died. Many who remained with the fick, and freely handled them as well as dead bodies, wholly efcaped the difeafe. Odiers who had loft their children and dependents, and in defpair fought death, by attempting to throw themfelves in the way of infection and afliduoufly attend- ing the fick, found all their efforts in vain ; they could not con- tract the difeafe. The diftemper has already prevailed fifty-two years, to this time, exceeding all preceding plagues : For Philoftratus was furprifed that, in his time, that calamity had prevailed for fif- teen years. What will happen hereafter is uncertain, fince ail things are at the difpofal of God who underftands the caufes of things and the events." Thus far Evagrius. See alfo Nicephorus lib. 17. ca. 18. The reader, is defired to attend particularly to the foregoing Relation of facts, as fome important conclufions will, in the fe- quel, be drawn from them, and other authorities hereafter to be fited. It will be remarked that altho authors fpeak of this peftilen- tial period, as of fifty-two years duration, as Evagrius and Gib- Bon have done, yet this is not accurate. Evagrius, from whom this number is copied, fays, the peftilence had then prevailed fifty-two years ; but it was ftill raging, and what was to happen afterwards, he could not determin. The truth is, plagues were uncommonly frequent during this period ; but the difeafe did not prevail without intervals. On the contrary* the years remarkable for mortality are fpecified by hiftorians, viz. 542 and 3, 547, 558, 562 to 565, 582 and 3, 587, and finally one of the moft deftructive periods of all was 590 and the few following years. Altho this was along and fevere period of calamity, yet from the beft accounts I can ob- tain, I fee no reafon to believe the mortality, in any given term of five or ten years, from 542 to 600, to have been greater, than in fome other periods of the fame duration. More people probably died in a fhort fpace of time, in the reign of the An- tonines—in that of Gallus and Volufian—and far more, in the dreadful plague of 134610 50.—It is even probable that in the lot lift 50 years of the 16th century, the earth fuftained as great a. lofs of inhabitants as in the fame fpace of time in the 6th centu- ry. General defcriptions are rarely correct, and Mr. Gibbon's unphilofophical, tho eloquent^oyn/^/Bg- defcription of the mife- ries of the human race, in Juftiwian's reign is calculated to mif- lead a carelefs reader. Evagrius indeed fays, this plague exceeded all preceding ones. This is natural; Thucydides faid the fame of the difeafe in his time. But we are more able to form a correct comparifon between the different epidemics that have prevailed, than the co- temporaries with any particular one. Agathius relates that in the peftilence at Conftantinople in 558, many died fuddenly as with an apoplexy. The moft ro- buft conftitutions furvived only to the 5th day. The critical period in the Athenian plague was the 7th or 9th. Thucydides makes no mention of the ftupor at the beginning of the diftem- per, nor of the volutatio humi, whirling of the earth, or dizzi- nefs, nor of buboes, nor of the effects of the difeafe on preg- nant women. Freind's Hift. of Medicine 416 et feq. Baron, vol. 7. 357,35^. Warnefred relates of this peftilence, in Liguria, where it was particularly mortal, that there appeared fuddenly certain marks " quaedam fignacula," upon the doors of houfes, on garments, and utenfils, which could not be waflied out but grew brighter by waftiing. The next year, appeared in men's groins, or other delicate parts of the body, tumors like nuts or dates, which were foon followed by intolerable fever, which extinguifhed life in three days. If the patient furvived the third day, he had hopes of recovery. I fhould have ranked this account among the fictions of a dit turbed imagination, had not more recent and well attefted facts given me reafon to credit it. The defcription of the terrible effects of this difeafe in Italy by the fame author, is melancholy and painful to the reader. The dyfentery which raged in France in 548 was accompanied with figns of the plague, and was nearly equal to it in mortality, The plague raged this year at Munfter, in Ireland. Short vol. j. 67. Smith's Hift, Cork 10, 102 The deflating plague of 590 was mortal almoft beyond ex* ample, and preceded or attended with extraordinary phenomena. In 588 Antioch was overwhelmed by a violent earthquake, and 60,000 people buried in its ruins. The inundation of the Tyber exceeded all that had been known, as did the drouth of the fuc- ceeding fummer. The intervening winter was equally remarka- ble for its feverity'—" qualem vix aiiquis prius recolebat fuiffe," fays Warnefred ; fuch as the old eft perfons could fcarcely recol- lect. Violent tempefts overturned buildings. About the fame time, fwarms of locufts appeared in Trente and devoured every fpecies of vegetable. In fome parts of Italy, they continued their ravages for five years. Cedrenus adds, that fifli died, and this mortality heafcribes to the freezing of the waters, page 332. —Modern obfervations prove the fallacy of the reafon here af- figned ; fifh do not die beneath a cover of ice ; but the death of fifh by means of earthquakes, and of ficknefs, is a common event. Aguft. Hift. 1156, 1157. Magd. Cent. 6. ca. 13. The order of the phenomena here related was this—the earthquake at Antioch—deluges of rain and inundations, tem- pefts, a moft rigorous winter, with a comet, exceflive drouth, peftilence. See alfo Echard's Rom. Hift. vol. 4. 246. Africa was almoft depopulated by this plague. So fudden and rapid was the difeafe in its action, that during a proceffion in Rome, inftituted by St. Gregory, on account of that calamity, no lefs than eighty perfons fell dead in the ftreet. Authors relate that the ferpents, wafhed from the mountains by the flood, and lodged on the earth, putrefied, and contrib- uted to the fubfequent plague. Gregory of Tours relates, that the plague, at that time, was introduced into Gaul by a veffel and her cargo ; but it did not fpread regularly from houfe to houfe, but ftarted up in diftant and detached plaees, like fire in a field of ftubble. Marfeilles and Lyons were made wafte by its mortality. It was moft fata! to the poor., Lib. 9. The following facts are related of the peftilence in Rome in io3 581, in the colleaion of German writers by Piftorius, page 683. Men died fuddenly, at play, at table, and in converfa- tion. Sometimes they fell dead in the ad of freezing, " dum fternutabant," fo that when one heard another fneeze, he turn- ed to him and exclaimed, " God help you"—which was the origin of a cuftom ftill obferved in fome countries.* Some- times perfons expired in the act of nodding or gaping ; which gave rife to the practice of making the fign of the crofs, on fuch occafions—a cuftom not yet obliterated. In 599, the plague in the eaft, in Africa and Rome, was dreadful. The death of the Emperor Mauritius, in 602, was preceded by the appearance of a comet. A fevere winter, about this time, killed the vines, and grain fuffered by froft and blight. The army of barbarians, marching to befiege Conftantinople, was fo harraffed and weakened by the plague, as to be compelled to abandon the enterprize. Cayanus their commander loft feven fons. Niceph. lib. 18. 35- Magd. Gent. 6. 13 and 7.13. Baron, vol. 8.138. Paul. Diac. lib. 4. The Magdeburgh Hiftory mentions a fevere winter in 604, which was followed by exceflive heat and drouth in 605. It places the firft comet of 606 in April and May ; the fecond in November and December. Cent. 7. 1 j. The year 615 was diftinguifhed for an epidemic elephantiafis in Italy, and the fhock of an earthquake. A comet appeared in 617 and peftilence in 618. Earon. vol. 8. 243. Short vol. 2. 207. Here is a period in which mention is made in hiftory of com- ets, without all their attendant calamities—one in 625, another in 632. It is the firft period of the kind I have been able to find ; and whether this filenge of hiftory is to be afcribed to the carelcffnefs of writers in that diffracted period, when the world was overrun by barbarians, or whether men efcaped ex- traordinary maladies, I am not able to decide. . An earthquake in Paleftine however marked the approach of the comet in 632. J Funct. Chronol. '' This cuftom was of higher antiquity. 104 Short mentions an earthquake at Antioch in 637 ; and fhocks in Paleftine in 638 which continued for 30 days—a comet in 639, and the plague in Syria in 640. But I have not the ori- ginal authorities. The Univerfal Hiftory relates that in 639, the plague was fo fevere in Syria, Arabia and in Medina, that the Arabs call that year the " Year of Deftruction." Vol 1. 485. A general peftilence in Italy is mentioned in hiftory under the year 651, but no particulars. A furprifing meteor had paffed the hcmifphere, in the preceding year. A violent plague in Conftantinople in 654. Functius Chron. Magdeb. Cent. 7. ca. 13. In 664 peftilence raged in Normandy, England and Ireland; and the hiftorian remarks that the fame difeafe which had af- flitfed England, afterwards invaded Italy in 665. Thus it would appear that this epidemic broke out firft in the north of Europe. Beda, Eccle. Hift. p. 136. Baron, vol. 8. 496. But the difeafe appeared in Egypt the fame year it did in England and Ireland. Paul. Diac. 980. In the fame year, in March, appeared a bow, iris, ftretching acrofs the heavens, and all flefh trembled, fays the pious Diac- on, expecting the laft day, Ibm.* In 669 or 70 appeared a fingular meteor or flame in the heav- ens—the next year an unufual ftorm that deftroyed men and cattle ; and in 672 the plague raged in England, of which died Bifhop Ceadda. Beda, lib. 4. Short mentions a comet in 672, and a fevere froft in 670, the year of the celeftial flame. In 678 according to Beda, and in 677 according to Sigebert, in the 9th or 10th year of Conftantine Pogonatus, appeared a comet in Auguft, which was vifible for three months. The year preceding was marked by moft calamitous tempefts which cut fhort the fruits of the earth, except leguminous vegetables ' Livy mentions a fimilar bow at Rome, during a great plague. 105 which were replanted and come to maturity. About the fame time appeared clouds of locufts in Syria and Mefopotamia. \JnU verfal peftilence followed thefe phenomena, in 679 and 680. England and Ireland were ravaged by it in 679 j and in 68o, during July, Auguft and September, Rome was laid wafte : " parents and children, brothers and lifters, were borne to their graves on the fame bier." Multitudes of people fled to the mountains, and the ftreets of the city were overgrown with grafs and weeds. A violent earthquake fhook Mefopotamia and other countries in 680. The locufts appeared two years before the earthquake, and in the fame year with the comet, ac- cording to Paulus Diaconus. A fevere drouth followed the comet, which in England lafted three years. See Paul. Diac. lib. 6. Beda, Ec. Hift. p. 116. Baron, vol. 8. 526, 544. Magd. Cent. 7. ca. 13. Muratori, vol. 6. In 681 famin, fays Beda, raged in EngJand, and in 683j peftilence " quas ex more famien fecuta eft," fays Paulus Dia- conus. In this latter year, if this was the fixteenth of Con- ftantine, according to Baronius, there was a violent eruption of fire from Vefuvius, which laid wafte all the neighborhood. Baronius, vol. 8. 564. Magd. Cent. 7. cap. 13. In the fame year Syria and Lybia were afflicted by famin and peftilence. Other authors place this laft peftilence two years later. The difeafe raged in Ireland in 685, in which year, there was a great inundation of the fea and the ifland of Inisfidda was torn into three parts. In 687, or according to others in 684, appeared a ftar, which was probably a comet, but without a coma. Smith's Cork, p. n. Magd. Cent. 7. Warnefied relates that a fingular meteor appeared in 685.* Notwithftanding fome differences among authors refpeeting the time of the events here related, we obferve all the violent agit- ations of the elements which introduce and attend great plagues. In 690 happened in Italy, one of the greateft inundations * We cannot but notice the coincidence in time between meteorj ^nd volcanic eruptions. 0 io6 from rain that was ever known—a fevere peftilence followed, " Peftis inquinoria." In 696, the fame difeafe raged in Conftantinople ; but no particulars are mentioned. f Magd. Cent. 7. A fevere winter preceded this peftilence, when the Thames was covered with ice for fix weeks. In 707 a terribly fevere winter is mentioned and a violent earthquake in Scotland. Short mentions peftilence in Scotland in 703 and in 713, but I have no particulars. In 717 happened a very fevere winter, fo that animals died of cold ; and the fame year, a great overflowing of the Tyber. The Saracens, in an immenfe army, marching to befiege Con- ftantinople, perifhed with cold, hunger and peftilence, and in the city, the plague extinguifhed the lives of 300,000 of its in. habitants. An earthquake in Syria in 718. Paul. Diac. lib. 6. 47. Baron, vol. 9. 15. Magd. Cent. 8. ca. 13. Cedrenus. Here is a chafm in the hiftory of comets of 40 years—at leaft I can find no mention made of them from 685, to 729, The fevere winter and the inundation of 717 however leave very little room to queftion the approximation of one at that time, and others doubtlefs appeared, during this period.* There was a great plague in Conftantinople in 724. In the year 725, a vapor like fmoke iffued for feveral days, from the fea between Thera and Therafia, the two iflands which, many centuries before, had arifen from the bottom of the fea. With this vapor iffued denfe fubftances, which, when expofed to theair,grew hardand formed a fpecies of pumice,with which the neighboring fea and the countries of Afia Minor and Macedonia were covered. A fmall ifland arofe at the fame time. Magd. Cent. 8. ca. 13. Muratori, vol. I. 151. * I La\fi fsund no author that mentions a cornet about this time; but it is worthy of remark that the fplendid comet of 1401 was calcu- lated to have a period of 343 years. This was therefore the fame which appeared in 1744. If this calculation is juft, the fame comet muft have appeared in 1058—in 715—in 372—and in 29 or 30; or near thefe years. Now it appears thnt there was «ne in 1038 and in 373 attended with all the ufual ca!amiti<.:—it is ♦licrefore prd'umeabUj that it appeared in 715 or if\ is? in 729 appeared two comets in January ; one preceding the fun, vifible in the morning; the other following it, was feen in the evening. The fame year the plague prevailed in Norwich. A plague in Syria raged in 732, but no particulars are men- tioned. The following year, the heavens appeared all in a flame. ,*. * Magd Cent. 8. ca. 13. The next peftilential period is remarkable for the violence of the operations of nature. In 740 a tremendous earthquake, or rather a continuation of fucceflive fhocks for twelve months, announced the commence- ment of a feries of calamities. It began on the 7th Kal. No- vember, and demolifhed buildings, ftatues and walls in Con- ftantinople, with a multitude of cities in Thrace, Nicomedia and Bythinia. Sigibert places thefe events in 741. In 742, or as others fay in 743, a moft fevere drouth was followed by moft terrible earthquakes. The next year appeared a comet and the year following, another ; and the third year af- ter the drouth, which was either in 745 or 6, according to dif- ferent authors, a remarkable thick darknefs covered the earth from Auguft to October. At this time the plague was raging at Calabria in Naples, and it continued to fpread with dreadful havock for feveral fucceeding years, in the countries of the eaft. So violent was it in Conftantinople in 746, that the living could not bury the dead ; but the bodies were carried in cart-loads and thrown into empty cifterns, and any place that would conceal them from the fight. Fatal indeed was the difeafe, when " eo- dem die aliquis mortuum efferebat, et ipfe mortuus afferebatur"—■ the man who buried a corpfe, was fometimes carried, the fame day, to his grave. In the order of the events here related authors agree. Ce- drenus mentions an extraordinary light or flame in the fky in 742, and a fimilar flame in the north, the year following. He mentions at the fame time a famin in Conftantinople ; and limits the darknefs to five days, from the 10th tp 15th of Auguft. Paulus Diac. Hift. Auguft. 10. 19. Magd. Cent. 8. 13. Baron, vol. 9. 144, 185. At the clofe of this period and while the plague raged in Con- ftantinople, in 749 or 50, Syria wa3 laid wafte by an earthquake io8 s-i-whole cities were exterminated—others removed entire ffohi mountains to plains, for a diftance of fix miles. This cataftro- phe correfponded with the approach of a comet. Short men- tions two. Magd. Cent. 8. 13. Baron, vol. 9. Short. 1. 8i. Such was the wafte of people in Conftantinople by the pre- ceding plagues, that the emperor Conftantine repaired the lofsby introducing the inhabitants of neighboring countries. in 760 or 61, for this difference occurs among good author- ities, appeared a comet, or light, called dokites, by the Greeks, from its refemblance to a beam ; which was vifible 10 days in the eaft and 21 in the weft.—In 762 appeared two other comets and the following winter was the moft fevere probably on record. It began about the firft of October, and lafted till February. The Euxine fea was frozen to the diftance of one hundred miles from the fhore, and the fnow and ice accumulated to the depth of thirty cubits. In this froft, the animal and vegetable king- doms fuffered great injury. On the breaking up of winter, the ice from the Danube and the Euxine was forced in huge maffcs, into the Bofphorus, and againft the walls of Conftantinople, which were greatly damaged. In March, falling ftars, or meteors were very frequent, and the fucceeding fummers were remarkable for moft terrible drouth, in which all fprings were exhaufted. Myriads of venemous flies appeared, and a defolating mortality concluded this feries of, difordered feafons. Paul. Diac. lib. 22. Baron, vol. 9. 271. Magd. Cent. 8. ca. 13. Short on Air, vol. 1. 82. Short mentions a fatal peftilence in Wales in 762. On the authority of Short, I have mentioned a mortality af- ter the fevere and unufual feafons of 763 and 4; but the original writers I have confulted do not mention it ; tho the fact may be found in others which I have not feen. It is altogether probable that fuch extraordinary feafons fhould occafion great ficknefs ; but it is equally probable that if any deftructive and general plague had followed them, the writers I have confulted would have mentioned it. I am led to notice this circumftance, by the confideration that ro9 n6 earthquake is recorded during this period. This circuit** ftance is of no fmall confequence in this inquiry ; and is a con- firming proof of the juftnefs of my fufpicions, that peftilence has an intimate connection with fubterranean heat or the action of fire. It appears that the plague, for the moft part, is violent and extenfive, in proportion to the action of the fire that exifts in and about the globe. The preceding peftilential period, be- ginning in 740, is a ftriking inftance of the truth of this remark. A great mortality happened in 766. In 767 a fevere drouth exhaufted all fprings and rivers and the year following was dif- tinguifhed Ly a comet. Peftilence j-.r: wiled in England in 771, and in Chichefter died 34,000 people. Short vol. 2. 268. Short mentions plague and famin in France in 779—a comet, an earthquake at Conftantinople, and peftilence in Scotland in 784 ; but I have no particulars. In the reign of Charlemagne, about the beginning of the ninth century, commenced a period of great mortality. A comet in 799, was followed by an exceflively cold winter in 800. Thefe events were preceded by violent earthquakes in Si- cily and Crete and in 798, an extraordinary darknefs in Eng- land of feventeen days. In 801 earthquakes fhook Italy, France and Germany, and thefe phenomena were repeated in 802 and 3. A prodigious tempeft in the year 800, levelled a multitude of buildings. In 802 the plague prevailed in various places, " propter mo- litiem hyberni temporis," fays the annalift Bartianus, by reafon of a mild winter. This however could not be the true reafon. In 808 a very mild winter was followed by the plague. In 810 happened the greateft mortality among horned cattle that is on record. In fome places in Germany, it deftroyed almoft all the fpecies. Lanciftus 146. Annal. Fuldenfes 810. In 811 fwarms of locufts from Africa invaded Italy and de- voured every green thing. In 812 appeared a comet, and after a chafm in the accounts ii5 for three months, convulfed by earthquakes. In the fame year commenced a famin, and a plague of three years duration, which defolated the whole earth. Cotemporary authors affirm that more than half the human race perifhed. The living were fatigued with burying the dead—" ut fepelientium taedio, vivi ad hue fpiritum trahentes, obruerenter cum mortuis." Such was the wearinefs of thofe that buried the corpfes, that the living before their breath had left their bodies, were tumbled into the graves with the dead. At the clofe of this horrible deftruction, Vefuvius difcharged prodigious quantities of lava which laid wafte the neighboring country. In 1009 was feen a comet in May. The beginning of the year the earth was deluged with rain, and a plague among the Saxons followed. The plague is alfo mentioned under the year 1012, with vi- olent rains and inundations, followed by an earthquake in 1013. But the neceffary materials for a detail are wanting. Magd. Cent. n. 13. Baron, vol. n. 27. Muratori, Tom. 5. £$■ In 1015 appeared a comet, attended with violent tempefts, and followed by famin in 1016. In 1017 another comet was feen, and the following year is noted as peftilential. But I have no particulars. In 1020 was feen another comet, and the winter was excef- fively fevere, fo that men perifhed with cold. This was fol- lowed by peftilence, in which the bodies of the infected gene- rated " ferpents," fays the hiftorian ; by which he probably means fome fpecies of worms. A fimilar fa& will be related from Thuanus in the 16th century. In 1021 was an earthquake, and the next year, the drouth and heat were extreme. In 1025 the fummer was wet. The plague raged in England, and in other parts of Europe, peftilence with violent earthquakes. Magd. Cent. 11. 13- In 1029 was an eruption of Heckla, and peftilence in fome parts of Europe. A comet in 1031 was accompanied, in its paffage, through llfj the fyftem, with great ftorms of wind and rain, producing vaft inundations. In Francej England and the eaft raged himinand peftilence. Locufts were added to thefe calamities, which Were fo fevere in fome parts of the world, that multitudes were com- pelled to leave their country. Violent earthquakes rrai Ltd this year, and what is ufual in the tempeftuous feafons occs:iiontd by comets diftinguiflied by volcanic eruptions, a fplendiu meteor, or globe of fire. During an eclipfe of the fun in 1032 or 3, authors mention a fingular phenomenon—a faffron color in the air, vhich rj.c to the human countenance a cadaverous afpect. But it might be merely the effect of a partial darknefs, with a hazyatmofphno. • A fevere winter in 1035, v;.s followed by an eruption of Vefuvius in 1036. The frequent coincidences cf this kind de- ferve notice. In 1037 is noted an igneous appearance in the heavens, like a beam. Thefe phenomena were followed by peftilence in Eng- land and in the Emperor's army, and with earthquakes. Magd. Cent. 11. 13. Univ. Hift. vol. 17. 166. Echard's Rom. Hift. vol. 5. 146. In 1042 commenced another diftrefling period. A comet in this year was followed by an eruption of Vefuvius in 1043 and fnow in harveft. The year 1042 was very tempeftuous and rainy ; the dykes in Flanders yielded to the fwelling ocean, and the low grounds were overwhelmed, with infinite defti uction. At this time began a general famin in England, France and Germany. The year 1043 ^as a^° diftinguiflied for rains and ftorms ; autumnal fnows were early, and an infectious difeafe carried off vaft numbers of cattle. In IC44 there was great mortality among men. In 1047 fell a deep fnow in the weft of Europe, which over- whelmed fmall trees, and lay till March. In March 1048 was a violent earthquake, followed by a tempeftuous feafon and great ficknefs. There was an eruption of Vefuvius the fame year, and an earthquake in October. The reader will remark a very regular connection between eruptions of volcanoes and violent winds. Magd. Cent. 11. 13. ay During this period the countries about the Hellefpont werej fjr three yeais, ravaged by locufts. In 1052 a tempeft is noted which demolifhed maroy buildings. In 1053 a comet which was followed by a famin. But- the f.'afons ate not defcribed. In 1057 fevere froft and great quantities of fnow'ruined the \ ines. During the following year, a comet was feen, the year after which the winter was very long and fevere, and in 1060 prevailed famin, and plague among men and cattle. In 1062 a trembling of the earth in Conftantinople, attended with thunder and lightning, was fucceeded by the plague. The riext year \v;s diflinguiflied by a con.et, vifible 40 days, a tem- peft of four days, deep fnow, and extreme cold, which proved fatal to vines, trees, birds and cattle. In 1065 feveral hundred thoufand Scythians, marching to in-> v;ulc the Roman empire, perifhed with peftilential difeafes. In 1066 a comet was feen in May, and a Cold winter fuc- ceeded. Egypt and Arabia, countries not fubject to earth- quakes, were violently convulfed in November, and a plague fptedily followed, which, authors affirm, fwept away one half the inhabitants. This was attended with famin. The north of Europe fpeedily felt fimilar calamities. Vio- lent earthquakes in 1068, and a comet in May, of apparent di- ameter equal to that of the moon, vifible 40 days, were fuc- ceeded by famin. The country in England from Durham to York was depopulated. Men fubfifted on dogs, cats and every unclean thing; or perifhed and their bodies were left to putrefy on the earth. The winters were unufually fevere. Magd. Cent. rr. 13. Murat. vol. 5. 44. Baron, vol. n. 370. In 1074 another comet appeared and a hard winter. The winter of 1076 was exceflively cold from Nov. to March, fo that the roots of vines were killed. In April 1077 appeared a comet, and famin and plague raged in Conftantinople with fuch mortality, that the living could not bury the dead. An earth- quake was experienced in England. Shocks were alfo felt in 1081 and 1082. In 1084 raged famin and peftilence ; the latter cut off the. lift Whole army of the Emperor Henry, in Rome. In 1085, Ruf- fia was laid wafte by locufts and the plague. The feafons were Unfavorable in England, the crops bad and a great mortality among cattle. In 1086, were great inundations in Flanders, Italy and other countries ; and in 1087 the fifh died in the rivers. Magd. Cent. n. Baron, vol. 11. 564. Stowc's Annals. Knighton. Hift. Ang. Script. 2353. Authors relate that in 1086, domeftic fowls left the houfes and fled to the woods. The two following years, the fame ca- lamities continued—bad feafons, murrain among cattle, and a violent fever, which appeared in the former year, raged in thefe and affected one half the people of England. In 1089 a burn- ing plague deftroyed mankind. Earthquakes diftinguifhed thefe pet iods. FunvStius Chro. vol. 1. 102. In 1091 appeared a comet; another in 1094; a third in 1096, and a fourth in 1098. In 1091, many violent tempefts happened which levelled buildings, 600 houfes were blown down in London ; fwarms of locufts darkened the fun, and the next year a plague raged, which •• the hiftorian relates to have arifen from the putrefaction of their bodies. The place where the locufts appeared is not named. A moft fevere winter in i093,occured after a very rainy fum- mer in England. The fummer of 1094 was alfo exceffively rainy.—The plague at the fame time raged in England, Gaul and Germany. A violent earthquake with a tempeft in 1094. The comet in Oct. 1096 was attended with great rains, which prevented the fowing of winter grain, and famin followed. Va- rious fiery appearances and meteors were obferved, during this period, and the winter of 1095 was fevere. In 1098 a peftilence invaded cattle, from the bad quality of their food, which- had been injured by great rains. This was the year of the laft comet above named, and in the following year, was a hard winter and a dearth. Syracufe was injured by an earthquake. Magd. Cent. n. 13. Matthew Paris, p. 17. Muratori, Tom. 5. 59. To the year 1099 or the following, is to be afligned the ter- rible inundation which fpread over the low lands in Kent, be- II9 longing to Earl Goodwin, and which, never having been recov. ered, now form the fhoals, called Goodwin Sands, of dange- rous navigation.—A fevere winter followed, and peftilence and famin in various places. Piftorius, vol. i. Anderfon, Hift. Com. vol. i. 176, It is probable that the events related in the two laft paragraphs happened in the fame year. The inundation is faid to have drowned in Holland one hundred thoufand people. A dark day is mentioned in the year 1099. In the year 1100 raged a peftilence in Paleftine, faid to have originated from the ftench of dead bodies. In Syracufe, a vio- lent earthquake demolifhed a tower, with the lofs of many lives. In 1101 a fingular meteor, and fuch multitudes of worms, called paplliones, from their refemblance to a pavilion, that they cover- ed two or three miles of country. Magd. Cent. 12. ca. 13. ' In 1103 a new ftar fhone for twenty-five days, and a comet of a bright flaming color—A great mortality happened this year, Magd. ibirn. Matthew Paris. In 1105, there was a difcharge of fire from Heckla, and in the fame year, a great quantity of fnow, a violent earthquake in Jerufalem, about Chriftmas, and about the fame time, a light in the weft almoft equal to the fun, and two mock funs. In Feb. of the following year, a cornet* of unufual fplen- dor for three weeks was vifible from three to nine o'clock, and two mock funs. A violent earthquake happened the fame year. Many meteors were feen and violent tempefts and inundation*, with myriads of infects in the air, marked the diforder of the elements.—The year was alfo noted for fterility of grain, and a confequent dearth—men were attacked with plague and unufual difeafes—" ignotis morbis, igne, Mamma, ardore invifibili homi- nes excruciati et abfque ad uftionis nota extincti." » Magd. Cent. 12. ca. 13. Muratori, Tom. 5. 485. The reader cannot fail to remark how regularly the mention of comets is accompanied with a failure of crops, meteors, and tem- pefts. We have proof ia modern times that thefe were not the * Suppofcd to be the fame as that which appeared in 5£iand in 168a 120 fictions of imagination. See the years 1769-70—1783-4— 17889. In 1107 appeared a comet with along coma—another wa3 feen in Normandy in 1108. Intheyear 1109 eryfipelous difeafes were epidemic in England ; which afflicted and deftroyed many people ; their limbs covered with black fpots, like carbuncles. Magd. Cent. 12. ca. 13. Sigebert. Polydore Virgil. In December 1109 appeared a comet, and in June 1110 another, which fpread its coma to the fouth. A fevere winter, with deep fnow and long continued cold, followed and fterility of grain. An unufual recefs of water in the Trente, fevere earthquake in Salop, and a mortality among men and cattle dif- tinguifhed the year 1111.—An earthquake and fevere plague are mentioned under the year 1112 ; but the year was remarkably for abundant crops of grain.—This year there was an extraor- dinary recefs of the water in the Britifh Channel for a whole day, fifh died in the water and domeftic fowls took flight into the wood* • Magd. Cent. 12. ex 13. Knighton, Hift. Ang. Script. 2379. Here we have an account of a progreflion in the peftilence— from the eruptive difeafes. of 1109 to the plague in 1112—This is the modern order. « In 1113 or, as fome authorities have it, in May 1114, a comet appeared, and in a period of diftrefling calamities. In this year there was an eruption from Heckla in Iceland. In May 1113 an extraordinary fnow very much injured trees and vegetables. In June a dreadful tempeft laid wafte whole countries, and the exceflive heat of the fummer produced dyf- entery and other peftilential epidemics. In 1114 many cities^ in Syria were proftrated by an earthquake ; and its effects _were felt in all the oriental countries. In November 1115 many houfes in Antioch were fwallowed up in a chafm rent in the earth. In January 1116 various places fuffered by fhocks of' the earth, and in 1117 all Italy was fhaken for forty days. In 1113 Flanders was overwhelmed by an inundation, which compelled many Flemmings to abandon their country, and they feftled in England. 121 This event feems to fix the approach of the comet in the year 1113. Severe drouth and a fingular recefs of the ocean left rivers dry in 1114. October 15th people walked over the Thames between London bridge and the tower. In December the fky appeared to be in a flame. The winter of 1115 was moft rigorous, and a terrible mor- tality fwept away the cattle. A comet appeared this year alfo. The year 1116 was rainy and fruits were deftroyed. In 1117 fwarms of locufts about Jerufalem devoured vegetation, and in England great damage was done by floods. In 1118 and 1119 earthquakes were violent. In 1120 the locufts and mice overran Judea, and Trent fuffered much from earthquakes. A fevere winter followed in 1121, and a drouth the next year, which occafioned a fcarcity of provifion, and men and cattle perifhed. In the foregoing period, no great peftilence is mentioned, but fuch difeafes as were occafioned by intemperate feafons, except among cattle. Magd. Cent. 12. Baron, vol. 12. 117. Muratori, Tom. 5. p. 60. Maitland's Hift. Lond. In 1124 happened a very fevere wimer, which deftroyed trees and vines—fucceeded by a cold fpring which retarded ve- getation. The following year was noted for a deftructive plague among men and cattle, in France and Brabant. Terrible was the famin in Italy, and in England fo many people perifhed with hunger, that dead bodies lay in the highways unburied. In 1125 the famin, accompanied with peftilence, continued in Eng- land, Germany and Italy. The feafon was excefiively wet and all fruits were injured or deftroyed. In 1126 appeared a comet in October, followed by a winter exccffively fevere, and in the following year, violent earthquakes occurred in Syria. Eryfi- pelous diftempers were fatal in England. In the peftilence of 1125, it was computed that one third of the people perifhed. Magd. Cent. 12. Baron, vol. 12. 160. Dufrefnoy. In 1130, 31 and 32, happened the moft deftructive murrain 122 among cattle and fowls ever known in England. In 1131 an exceflive drouth in France. In October 1133 appeared a comet. The fame year, Eng- land was fhaken by earthquakes, and inundations continued a whole month. Authors affert that the fun exhibited fingular appearances, changing its figure and dimenfions, and that there was a remarkable intempcrature in the air. In modern times, the face of the fun is often disfigured with fpots, and it is not unphilofophical to fuppofe that moving vapor in the air may fud- denly change its apparent diameter. In 1134 the fea broke into Flanders, as it did in the follow- ing year. This year was rainy. In 1135 the drouth deftroyed vegetation and occafioned a dearth. The Rhine was fordable in almoft any place. Terri- ble tempefts and earthquakes and an eruption of Vefuvius mark* ed this period, and a dreadful plague enfued. Short, vol. 1. 118. The eruption of Vefuvius was in 1136 and a fecond in 1139. The fummer of n 37 was as remarkable for drouth, as was that of 1135. The plague was univerfal. The diforders in the elements occafioned a long and defolating famin. Magd. Cent. 12. Piftorius, vol. 1. 156. Matthew Paris. Knighton mentions the fun's changing its form in 1133, and adds that a darknefs happened which rendered a candle neceffary in the day time. Chronocon. From this it is probable the fun prefented appearances, like thofe which we obferved on the 19th of May 1780, and which are ufual in dark days. The reader will remark the occurrence of fuch days, in years when electricity fliakes the earth, or fire and lava are difimarged by volcanoes. He will note alfo the drouth that preceded the eruption of Vefuvius in 1135 and 11 ?R. In U40was an earthquake'in England. In 1141 a very fevere winter. In 1143 the air, for a mile in extent, was filled with an unufual infect, with the body of a worm and the fize of a fly. A general plague among men and cattle began the fame year, and raged with great violence in various countries, In n 44 or as fome authors relate in May 1145 appeared t comet, illuminating the heavens, and the fame year were violent earthquakes. In 1146 another comet, and the plague incredibly fatal. A famin prevailed with diftrefling feveritjs, for 12 years, including the years juft named. Magd. Cent. 12. Muratori, Tom. 5. p. 65. Piftorius, Germ. Script. If men, at this period, had any refpite from natural evils, the intervals were very fhort. In 1150 a very fevere winter and fevere peftilence are recorded in the Saxon chronicle, together with fanii 1 and an eruption of fire in Iceland. Earthquakes, inundations and peftilence marked the fubfequent years. The years 1151 and 2 are mentioned to have been very rainy—the winter of 1153 and 4 fevere, and the fummer of 1156'excet fively dry. Thefe phenomena follow each other fo rapidly, and are related with fuch brevity and in general terms, that it leaves the mind at a lofs to what influence to afcribe the difeafes which afflicted nations for a feries of years about this period. In this gloomy and barbarous age of the world, hiftory is concife and deftitute of accurate obfervations. In 1157 there was an eruption in Iceland, with a very cold winter. In 1158 an eruption of Vefuvius, an earthquake in England, and an inudation of the Tyber. Peftilence appeared in Scotland in 1154. Not long after thefe events, Antioch, Tripoli, and Dama£ cus were convulfed by an earthquake, with the lofs of 20,000 lives. After an interval of more than 300 years, during which I find in hiftory no account of any eruptions from Etna, this vol- cano is introduced to our notice by an almoft continual eruption from 1160 to 1169. Earthquakes were violent in 1161—in Sicily an inundation drowned 5000 people—in 1163 one of the greateft inundations in Friefknd ever known, preceded by a very fevere winter. At this time the plague was raging in Mi- lan, Normandy and Aquitain. Unufual darknefs is mentioned in 1164. In England, the fea overflowed twelve miles of country, deftroying men, cattle and improvements. In 1165, a comet appeared with a long coma ; 12,000 people perifked by an inundation in Sicily, and Norfolk and Suffolk in England 111. were fhaken by an earthquake. Moft of Frederick Barbarofla'i army perifhed by the plague in 1167. This period was remark; able for great wind and hail. In 1169 the eruption of Etna was very violent ; Catana was demolifhed by an earthquake, and 15,000 people perifhed «—Afia Minor felt the fhock. In the next year, fo general and tremendous were the earthquakes, that many of the beft cities in Syria, Paleftine and other countries, were laid in ruins. Germany fuffered by earthquakes and inundations. Peftilence marked this period, and in 1172 a malignant dyfentery raged in England. In 1174 mention is made, for the firft time, of an epidemic cough or catarrh. There is however no queftion that influenza and meafles always preceded or accompanied peftilence in the ancient and middle ages, as they do in modern times. Authors have neglected to record the prevalence of all the minor epi- demics, or nearly all, until after the invention of printing. In 1175 hiftory mentions an eruption of Etna, peftilential difeafes in England and a famin. In 1176 a long and fevere winter, and an irruption of the fea into Holland with immenfe deftruction—a fevere drouth followed with a lofs of feed time^ The year 1177 was diftinguifhed for violent winds. In 1178a comet was fucceeded by a moft rigorous winter, and deftructive inundations. On the 1 ith of September, was a dark day, with lingular appearances of the fun and moon. A- nother comet is mentioned in 1179 and a great hail ftorm. In 1181 appeared a comet, and earthquakes, with an eruption of Etna, marked this period.—At this time Denmark was al- moft laid defolate by exceflive rains, famin and peftilence, while Germany loft half of its inhabitants by the plague. Some al- lowance muft be made for exaggeration in the accounts of the more deftructive plagues. This was an age of fuperftition, and the imaginations of men were fufceptible of ftrong impreflions. In 1185 is recorded a moft violent earthquake, over Europe. 'Calabria was overturned, and thoufands perifhed. On the Adriatic, a whole city was fwallowed up, and the fhock was ifelt to the Baltic. 12$ • In 1186 Ruffia and Poland were defolated by locufts and peftilence. The winter was fo mild, that the following harveft was in May, and vintage in Auguft. In Carinthia, the locults devoured every green thing. An unufual conjunction of planets happened, this year, in Libra ; and fo great was the alarm, in that ignorant and credu- lous age, on account of the calamities predicted by aftrologers, that a folemn faft of three days was appointed by the Archbifhop of Canterbury. Luckily no uncommon event happened in Eng- land, until the next year, when peftilential difeafes prevailed a* mongmen and cattle. In 1188 the plague was in Rome. Magd. Cent. 12. Murat vol. 5. p. 70—6—182. Univ. Hift. vol. 32. no. Henry Hift. Brit. vol. 3. 38a I have no accounts of comets in this period from 1181 to 1211 ; altho it is probable that feveral were vifible. How far may we luppofe the conjunction of all the planets had any influence in producing the remarkably mild winter of 1186 ? In January 1193 was a remarkable aurora borealis. In 1193 and 4 exceflive rains injured the grain and produced a dearth. In England an acute peftilential fever was epidemic and left in health fcarcely a number of perfons fufficient to tend the fick. The ufual forms of burial were neglected, and dead bodies were thrown into graves in piles. A fevere winter put a ftop to this epidemic. Brompton, with a Batural partiality for religious houfes, informs us that the only places exempted from the deftruction of this peftilence, were the monasteries—Cotem- porary with this difeafe was an earthquake and a fingular fiery appearance in the fky. Short places this fever under the year i 196and calls it a " burning ague." Seethe years 1001 and *723- Brompton's Hift. Ang. Script. 1271. Magd. Cent. 12. Short, vol. 1. 130. The winter of 1200 was cold; the fummer of 1201 was very rainy ; and the winter fucceeding was fevere almoft beyond example. In 1203 was a fore famin from bad feafons. In 1205 a rigorous winter and a great hail ftorm ; in 1206 an erup- tion of Heckla ; but I have no account of any epidemics that prevailed. 126 In i2to was an eruption of Heckla, and a cold winter. In 1211 appeared a cornet, in May, vifible for 18 days. Great tempefts marked this period with inundations. In 1212 Venice and Damafcus were violently agitated by earthquakes, and in Sicily thoufands perifhed by an inundation. Thefe phenomena were the heralds of a fevere peftilence, which, in 1213, was fo fatal in Italy, that authors affirm fcarcely one tenth of the in- habitants furvived. In the year following appeared two comets. The year 1219 was diftinguifhed for the approach of a large comet, diftreffing inundations, in one of which perifhed 36,000 inhabitants, an earthqaake and a volcanic eruption in Iceland. In 1220 the plague was fo fatal in Damietta, that authors re- late three perfons only furvived out of 70,000. By this we are to underftand the difeafe to have been extremely mortal ; but we muft reject the literal meaning of fuch relations. It is doubt- lefs true that the peftilence of this period has rarely been ex- ceeded in mortality. This period was very calamitous in the north of Europe. In 1221 Poland was afflicted by exceflive rains, and the floods which followed fwept away whole villages. The winter fuc- ceeding was fevere, fo that frozen wine was fold by weight, while famin and peftilence almoft defolated Europe. In moft countries, the living could hardly bury the dead ; and in fome cities, fcarcely a perfon furvived. In the year 1222 appeared a comet of unufual magnitude and the fummer was exceflively dry. A froft, with deep fnow in April, deftroyed the fruits. In autumn the earth was deluged with rains and fwept with violent winds. An earthquake fhook Germany and Lombardy ; in Cyprus two cities were demolifhed 5 the fhocks were frequent and continued for two months, in Brixia, Venice, England and other countries. The plague raged, for three years, with uncontrolable fury, in Germany, Hungary, France and other countries ; falling on cattle as well as man. During this dreadful period, the difeharges of fire and lava, from the volcanoes in Iceland, exceeded what had been before known in the fame fpace of time. There were two eruptions in 127 1222, one from Heckla ; the other from Reikenefe ; and the eruptions of the latter were repeated in 1223, 1225 and 1226. In 1224 was a fevere drouth ; in 1225 a rigorous winter, fol- lowed by a dearth, and mortal difeafes among fheep. Let any candid man obferve the natural phenomena accompa- nying this defolating period, from 1219 to i2 2€ ; and decide for himfelf how far the fire or electricity of the fyftem is an agent in preducing them, and the attending difeafes. We obferve here the progrefs of peftilence to be the fame as in modern times. The plague appeared in Egypt almoft at the fame time with the comet, and firft derangement of the elements in 1219 and 1220 •, but was two, three, four and five years later in the high northern latitudes. No comet is mentioned in the hiftories of this dark period, as far as I can find, from 1222 to 1240 ; but that there was one, in the vicinity of the earth, between 1228 and 1233, is very probable. In 1228 an inundation in Friefland demolifhed whole towns, and it was eftimated that 100,000 people perifhed. Great rains in fummer and exceflive heat were followed by a fevere winter, with deep fnow. In 1230 the waters of the Tyber rofe to the flairs of St. Peter's Church, and drowned the lower city. July and Auguft were exceflively hot. An inundation of the Danube in 1232, and in 1233 fo fevere a froft, that rivers were converted into highways in Italy ; and earthquakes marked the year, with a dark day. During this period from 1230 to 1233, France, Denmark and Italy were wafted by dreadful famin and plague. Thefe ca- lamities continued in 1234 and 5, in England and France. In London alone 20,000 people were ftarved. Worms and locufts devoured the fruits of the earth. The winter of 1236 was rainy—the following fummer ex- tremely dry, and in England moft diftrefling agues were ep- idemic. In 1237 was an eruption of a volcano in Iceland. In 1239 peftilence again raged—a new ftar, like Lucifer, appeared. Famin was fo fevere that perfons fed on human flefh. 128 In 1240 a comet appeared in Feb. and was vifible a month. Mortal difeafes prevailed, and authors relate that the fifhj on the Englifh coaft had a battle, in which eleven whales and a multitude of other fifh were flain and eaft afhore. The caufe to which this phenomenon is afiigned is laughable enough; but the fact is important; for it ftrengthens modern obfervations, that when peftilential difeafes prevail on the furface of the earth, fifh often perifh beneath the water. Of this no doubt can re- main ; and this alone demonftrates that the peflilentlal caufe is as powerful or nearly fo, at the bottom of rivers and the ocean, as on the earth—a fact that reduces the theory of propagating the fomes of epidemic difeafes in veffels, clothes and fimilar articles, from one country to another, to a thing of very trifling confideration. The winter of 1240 was very fevere—the fnow was deep and cattle perifhed. An eruption of fire in Iceland is noted the fame year. In 1242 the Thames rofe by means of exceflive rains and overwhelmed the country for fix miles about Lambeth. The years 1243 and 4 were remarkable for continued drouth, mete- ors and a moft fatal plague.—An eruption of fire in Iceland u 1245. In 1247 a violent earthquake was experienced in England, and in September a fatal plague. The earthquake was in Feb- ruary and followed by a very rainy fummer. The winter fol- lowing was fo mild, that people wore their fummer clolhes; but from March to May was cold. The fummer of 1250 was rainy and tempeftuous, followed by a hard winter. The fummer of 1251 was intolerably hoi, and epidemic difeafes prevailed, with great mortality. In 1252 late frofts in fpring, and fucceediag drouth deftroy- ed the fruits of the earth. At the clofe of July came great rains, vegetation ftarted, but great mortality prevailed among cat- tle. At Michaelmas began the plague in London, which fpread over England, and raged till Auguft following. This is one Miftance of the plague's appearing in autumn, running through 129 the winter, and ceafing about the time, in the hot feafon, when that difeafe ufually begins. The winter of 1254 was rigoroufly cold, a murrain among fheep was very fatal, and in England and France a mortal dif- temper among horfes called the evil of the tongue, but it is not defcribed. In 1255 appeared a comet; tides rofe to an uncommon height; rivers fwelled with exceflive rains and tempefts levelled buildings. In 1256 the rains and tempefts were equally violent, and another comet appeared. In 1257 the fummer was alfo exceffively rai- ny. From thefe rains came a dearth of corn in England and France in 1258, which was alfo rainy ; and famin and difeafes made havoc with human life. Fifteen thoufand perfons perifhed by hunger in London ; but I have no account that the plague prevailed at that time. To this feries of wet feafons fucceeded fevere drouth in 1259 and 1260 ; and the mortality continued till the fummer of 1259 —after which plenty fucceeded to want. The year 1261 was rainy in England and Scotland, and a dearth was the confequence in the following year. In 1262 an eruption of a volcano in Iceland. In 1263 a fevere froft in winter converted the Thames into a highway for men and horfes. In 1264 a comet was vifible from June 20th to September 28th and peftilential difeafes fwept away horfes and cattle. In 1266 fwarms of Palmer worms devoured all vegetables in Scotland, and feveral villages on the Tay and Froth were fwept away by floods. Thefe were preceded by a remarkable halo. In 1268 appeared a comet, and violent tempefts and rain are noted, together with fterility of grain and dearth in Auftria and Sicily. In 1269 the winter was extremely fevere; horfes and car- riages pafling on the ice over the Thames. A plague raged among the Crufaders, on their march to the holy land, of which died the French king and his fon. Some authors mention a comet of ftupendous magnitude under this date ; which is prob- j»bly the fame as that noted under the foregoing year. R *3° In 1274 was a great earthquake and a comet of frightful af- pect—an earthquake alfo in 1275. In this year, it is related, the rot among fheep was firft known in England. As this was faid to be an imported dife?ie, it is proper to ftate how it was introduced. Short on Air, vol. 1. 155, fays, " This year, a rich Frenchman brought into North- umberland a Spanifh ewe, as big as a two year old calf, which ftieep being rotten, foon infected the country, fo that the difeafe overfpread the whole kingdom, and lafted 25 or 28 years, till it left very few fheep alive. This was the firft rot ever known in England." The reader will judge which is the greater calf, the man who gravely tells or the man who believes fuch a tale as this. Hiftorians fix upon the year 1277 for the formation of the Dollert Sea, between Groniagen and Eaft-Friefland, by a great inundation, which overwhelmed 33 villages irrecoverably ; with many farm-houfes in the open country. In 1280 a great inundation was followed by a very cold win- ter. In 1281 Poland was afflicted with famin. The winter of 1282 was the fevereft then remembered; an earthquake fhook Italy and a plague raged in Denmark. In 1283 the fame mal- ady prevailed in Scotland. In 1284 the winter was one of the mildeft ever known ; the year was alfo remakable for great tempefts, an unufual darknefs and an eruption of Etna. The year 1285 was noted for a fimilar darknefs, moft parching drouth and the commencement of a famin in England. This drouth was followed in 1286, by the approach of a comet. In this year, Pruffia was infefted with a new fpecies of worms, whofe fting was poifonous. Swarms of flies and pefti- lential fevers in Spain nearly deftroyed the army of the French king, then making war on Arragon. In 1287 fifteen iflands in Zealand were overwhelmed by an inundation, with the lofs of 15,000 inhabitants. In 1288 the fummer was exceflively hot and dry. Grain was however abundant in this and the preceding year. The drouth was followed by great mortality and a fevere winter. In 1293 a comet was vifible, and a great fnow ftorm happen- ed in May. Italy was fhaken by earthquakes. In the follow- ing year, England was diftreffed by fevere famin, thoufands of the poor perifhing with hunger. A fevere drouth exhaufted all the fprings and rivers, grafs withered and cattle were fed on ftraw. The winter of 1293-4 was extremely cold, and an eruption of Heckla happened in 1294. In 1295 and 6 many countries were afflicted with famin, and in 1297 the plague prevailed in Scotland. A comet of great magnitude appeared in 1298, or as other authors fay, in 1299, and others in 1300 ; whofe approximation was attended with violent earthquakes in Germany, and other places in 1299, and with an eruption of Heckla in 1300. The year 1298 was noted for a great mortality among the Jews, and multitudes perifhed in the eaft with various difeafes in 1299. In 1305 appeared a comet, attended with fatal peftilence, A hard winter followed, and the Rhine was covered with ice. In 1311 mount Heckla difcharged its fiery contents ; in 1312 appeared a comet, and a three years famin commenced in Bo- hemia and Poland, which was exceedingly diftreffing. Men be- came like wolves and preyed on human flefh. In 1314 inceffant rains deftroyed the grain; a comet ap- peared in December following, and in 1316 raged a defola- ting dyfentery in England, accompanied with an acute fever, which, like the true plague, left fcarcely fur vivors to bury the dead. The famin continued to rage with all its horrors. Horfe flefh was a delicious difh. Wheat fold at forty fhillings the quar- ter ; equivalent to £30 fterling in thefe days. In 1318 the winter was fevere, and in 1319 the plague pre- vailed in England. A murrain fpread among cattle, at the fame time, with fatal deftruction.* In 13 21 the drouth was extreme, and there was an eruption of Etna. Eruptions of Etna are alfo mentioned in 1323, 1329 and 1333, and a fevere winter, in the firft of thefe years 1323, which covered the Baltic with ice. The plague raged in 1325. The year 1330 was rainy and the crops indifferent. The year * I have no account of any comets from 1315, to 1337—which may be owing to the defect of my hiftorical materials. Hi following, Ireland was diftreffed by famin, but Dublin was re- Jieved by plenty of fifh, called Thurlhsds, which had not been feen there for ages. In 1332 was an eruption in Iceland. In 1336 grain was abundant. A violent earthquake fhook Venice, and a fucceeding plague laid wafte the city. This was preceded by numerous abortions.f In 1337 happened a feverely cold winter, without fnow. Two comets were vifible, one four months, the other two. The plague prevailed in Nuremberg and other parts of'Europe. The winter following was alfo fevere. Piftorius places thefe comets in 1336, and mentions an inundation at Florence. At this time, Europe was, for three years, ravaged with locufts. In 1339 or 40, appeared another comet. Great floods, an eruption of Heckla, and a fevere winter followed, which cov- ered the north fea with ice. See Short on Air, vol. 1. Piftorius, vol. 1, and 2. Dufref- noy's Chron. Henry's Hift Eng. vol. 4. 500. Camden's Britannia. Fun^£till!,, Chron. Knighton's Chron. In travelling through the dark ages, we find but few intereffc. ing defciiptions ; and nothing could have induced me to under- take the tedious detail of detached facts reflecting peftilence, but a ftrong defire to afcertain all that can be difcovered of the operations of nature, in producing epidemic difeafes. It is of infinite importance, in difcuffing this fubject, to know whethef certain phenomena of feafons, of fubterranean fire, and unufual animals, uniformly attend peftilence ; and to afcertain, if poffi- ble, the order in which they proceed, for the purpofe of dif- covering whether they are connected with each other as caufe and effect. Barren as the hiftory of the barbarous ages really is, we yet find it to contain a great number of facts, that will aflift us in developing the caufes of epidemics. The fubfequent pe- riods of the world furnifh more ample materials—we now ap- proach the morning of fcience, when the clearer lights of more accurate hiftory will illuminate our path. f To repair the wafte of population, the Senate pafled a decree in- viting perfons to come and relide in the city, and promifing them the rights of citizenfhip, after two years refidence. Howel's Survey. ■*33 SECTION IV. Hiftorical View of peflilentlal epidemics, from the year "340* to 1500. X HE peftilence next to be defcribed was the moft general and awfully diftreffing that the world ever experienced. The prccife year when it appeared in Afia, where it began, is not af- certained ; but probably about 1345, perhaps a year or two ear- lier. The hiftories of that age relate, that it commenced in Cathay, China, and was preceded by the burfting of a huge meteor or globe of fire ; or as others relate, the fire burft from the earth. Thefe accounts were taken from Genoefe feamen, and are recor- ded by Villani; but Dr. Mead, with that obftinacy that rejects truth when oppofed to preconceived theory, thinks the report incredible, and queftions not the difeafe originated in Egypt. Had he ever examined the fubject, like an impartial man, he Would have believed the account of the feamen, for there is not a more certain phenomenon in nature, than the appearance of meteors and the explofion of fire in peftilential periods. Villani, book 1. ch. 2. Mezeray, Tom. 1. 798. This plague appeared in 1346 in Egypt, Syria, Greece, Turkey; in 1347 in Sicily, Pifa, Genoa and other parts of It- aly ; in 1348 it appeared in the fouth of France, firft in Avig- non, which is not a maritime city, but at a diftance from the fea, and afterwards in other parts of the kingdom and in all the fouthern provinces of Spain. At the clofe of the fame year, it made its appearance in England, firft in Dorfetfhire, and foon trayelled over the whole country. In 1349 it overrun Ireland, Holland, Scotland, and in 1350 all Germany, Hungary and the north of Europe. r3* This peftilence was remarkable for raging in winter as well as fummer, even in the north of Europe. In France it firft ap- peared at Avignon in February and prevailed there nearly a year. Muratori, vol. 3. part 2. 588. Short has placed its firft appearance in the fouth of England in September. But Archbifhop Parker has placed its origin juft after Chriftmas. His words are, " Ea ftatim poft nativitatis dominicaj celebratum feftum, ipfa nimirum hyeme et rerum omni- um ad victum neceffarium copia, cum vix ullacontagionis fufpicio oriri mortalibus potuit, incepit." " Immediately after the feaft of our Lord's nativity, in winter and amidft the greateft abun- dance of provifions, when there could be no fufpicion that a contagious difeafe would arife among men, the plague commen- ced." It raged about five months and according to this author* •ceafed in May following ; altho other authors relate, that it had not gone through the kingdom till late in the fummer. Parker's Antiq. Brit. p. 360. In the Englifh Annals by William Wyrcefter, in the black book of the Exchequer, it is faid that this plague prevailed in the parts of London and its vicinity in autumn 1349. Thefe different accounts of the time of the firft appearance of this difeafe, are reconcileable on the principles which mod- ern obfervations have unfolded. It is found that the plague is always preceded, for fome months, and in fome inftances, for two or three years, by other malignant fevers, which increafe gradually to the violence of the true plague ; and often the de- , grees of violence are fo gradual, that phyficians themfelves can hardly determin a line of diftinction between the malignant dif- eafe, which is the precurfor of the plague, and the plague itfelf. That is, they are at a lofs to know where the malignant dif- eafe ends and the plague begins. Hence all the difputes, at the commencement of a peftilence, whether the difeafe is the plague or not—a circumftance which appears to have marked the origin of all great plagues, and yet phyficians and philofophers in Eu- rope feem never to have fufpected the caufe.—Thefe facts will be hereafter demonftrated, and they annihilate at a blow the whole doctrine of the propagation of that difeafe from country to coun- try by infection. l35 ■ From the uniform operations of nature in the cafe of epi- demic peftilential difeafes of the kind under confideration, there muft have been in England, during the fummer, previous to the appearance of the plague, malignant fevers, which might ap- proach to the violence and fatality of the plague. This circum- ftance might create a fmall difference in the accounts of the ori- gin of the plague—inaccurate obfervers miftaking the one dif- eafe for the other—or rather naming the previous putrid fever, the plague, before it put on the characteriftic fymptoms. It is poflible however that thefe authors may refer to the com- mencement of the difeafe in different parts of England. This formidable calamity deferves a particular defcription, with all the phenomena attending it. In 1347 appeared a frightful comet, in Auguft. Preceding "and during the prevalence of the difeafe, the whole earth was fhaken by moft tremendous earthquakes. All Germany was fhaken in 1346. In 1349 on the 9th of Sept. Sicily was fhaken to its foundation, together with' all Italy. In Greece many cities were overthrown, and in many places towns and caftles were demolifhed. Thoufands of people were fwallowed up and the courfes of rivers were obftructed. Over Avignon was fufpended a meteor or pillar of fire for an hour. The heavens were at times illuminated as with flame, and meteors were frequent. I have no particular defcription of all the feafons, during the five years, in which this mortal peftilence defolated Europe. But the year 1347, the year of the comet, was, in England, exceffively rainy, and the air humid.* Short, from Johan ColedeBillona, mentions that a hot air, cloudy and moift at- mofphere had continued for fome years, and that a malignant, contagious peripneumony followed in all Europe. But unfortu- nately the compiler leaves us in the dark as to the precife time of * Mutius, in the collection of German hiftory, fays that the whole year 1348 was foutherly, moift weather, but there were no heavy rains to cool the air. Fruit was abundant, but corn was not nutri- tious. See vol 3. 241.—In England the rains continued from May to Chriftraas. *36 its appearance, and whether before or after the other forms of this peftilence. Mezeray relates that in China, the difeafe originated from a vapor, which burft from the earth, was horribly offenfive and confumed the face of the country through an extent of 200 leagues. This account may be inaccurate, but is not to be wholly rejected. That fome action of fubterranean heat was inftrumental in generating the difeafe, is very probable ; or at leaft that fome phenomena of fire accompanied it, becaufe this fuppofition is confonant to the whole feries of modern obferva- tions. The peftilential ftate of air, in that period, is ftrongly marked by the appearance of myriads of unufual and loathfome infects, not only in China, but in Europe. They are defcribed as young ferpents, or as venemous infects, or as large vermin with ' tails and eight fhort legs—in which defcription, probably, a frightened imagination had fome fhare of influence. But of the fact of their exiftence, there can be no doubt. In the Oufe there was a great inundation juft before Afcen. fion day, and in York began this plague fpeedily after the flood. The fymptoms of this fatal malady were—violent affection in the head and ftomach, buboes and other glandular fwellings j fmall fwellings like pimples or blifters ;. ufually a fever, and a vomiting or fpitting of blood.—The fwellings in the glands were infallible figns of the difeafe ; but the moft fatal fymptom was, the pimples or blifters fpread over the whole body. Hemorrha- ges from the mouth, nofe and other parts, indicated a univerfal and fudden diforganization of the blood. " The patient ufually died in three days or lefs—which denotes the virulence of the poifon, or rather the activity of the difeafe, which deftroyed the powers of life in half the time, which the bilious plague ufually employs. The peripneumony which was epidemic about the fame time, appeared in a burning fever, infatiable thirft, a black tongue, anxiety and pains about the heart, fhort breath, a cough, with expectoration of a mixed matter, open mouth, raging delirium, fury, red, turbid or black urine, reftleffnefs, and watchings, 137 black eruptions, anthraces, buboes, and in fome, corroding ulcert over the whole body. The difeafe ufisally terminated the 4th day, fometimes not till the 7th. The blood was black and thick; but fometimes greenifh and watery or yellowifh.—Venefedtion was certain death. The difeafe baffled medical fkill—the only remedies that appeared to relieve, were laxatives early admin- iftered, cupping and fcarification, leeches applied to the hemor- rhoids, and inwardly, infufions of mild, diaphoretic, attenua- ting, pectoral vegetables. It will be hereafter proved that malignant pleurify andperipneu- mony ufually form a part of that feries of difeafes which always occur during a period of general contagion. When plague and yellow fever occur in fummer, in northern climates, pleurify and peripneumony often affume, in winter, great and even peftilential violence. This plague was fo deadly that at leaft half or two thirds of the human race perifhed in about 8 years. It was moft fatal in cities, but in no place died lefs than a third of the inhabitants. In many cities perifhed nine out of ten of the people, and many places were wholly depopulated. In London 50,000 dead bod- ies were buried in one grave yard. In Norwich died about the fame number. In Venice died 100,000—in Lubec, 90,000—■ in Florence the fame number. In the eaft perifhed twenty mil- lions in one year.—In Spain the difeafe raged three years and carried off two thirds of the people. Alfonfo 2d. died with it while befieging Gibraltar. In this fatal period, the apprehenfion of death deftroyed the value of property. In England, and probably in other coun- tries, cattle were neglected and they ran at large over the coun- try. The corn perifhed in the fields for want of reapers ; whole villages were depopulated; and after the malady ceafed, multi- tudes of houfes and buildings of all kinds were feen mouldering to ruin. A horfe which before had been worth forty fhillings, after the ficknefs, fold for half a mark. Altho in the year preceding there had been a plenty of pro- vifions, yet the neglect of agriculture during the general diftrefs produced a famin. Such was the lofs of laborers, that the few S Ill furvivors afterwards demanded exorbitant wages, and the Par- liament of England was obliged to interfere, and limit their wa- ges, and even compel men to labor.—See 23d Edward 3. A. D. 1350. The preamble ftates, that a great part of the people, efpecially workmen and fervants had died of the late peftilence, and thofe who furvived, feeing the neceflity of men, demanded exceflive wages. This difeafe was particularly fatal in Denmark—all bufinef; was at a ftand, towns were deferted, and all was terror and def- pair. It reached the higheft northern latitudes ; it broke out in Iceland, and was fo fatal, that the fettlements there are fup. pofed not to have fince recovered their population. It was cal- led the forte diod, black death. In fome places people attempted to efcape infection by taking their families on board of veffels, and putting to fea ; but it, was in vain ; they were feized in every place, without regard to age or fex. In 1348 the malady fwept away the Greenland merchants and feamen. This difeafe alfo, or fome other caufe deftroyed the colony of Danes in that country, for it was extinguifhed and has never been found or heard of to this day. This peftilence was remarkably fatal to the monks and regular clergy of all defcriptions. In one fociety at Montpeliers, of 140 members died all but 7 : About the fame proportion perifhed in Magdalen Society. In Marfeilles, of 140 not one furvived. But a circumftance related in Knighton's Chronicon deferves particular notice. At Avignon where the difeafe firft appeared in France, 66 of the Carmelites had died, before the citizens were apprized of the fact ; and when it was difcovered, the re- port circulated that the brethren had killed each other. An important confequence refults from the fact—that this plague firft appeared in a monaftery, which might be crouded with lazy, idle, filthy monks; in a city not commercial, nor a fea port. There was no idea of any imported infection ; but there muft have been ftrong local caufes, which firft excited into action the general contagion which, at that time, pervaded the atmofphere over the whole globe. Such was the havoc made by this peftilence among the clergy *39 in England, fays Knighton, that a vicarage which before the plague, might have been fupplied for four or five marks a year, or two marks and the man's board, was raifed to the price of twen- ty marks or twenty pounds. Col. 2600. This peftilential period was preceded and attended with all the ufual pheno-nena of fatal Epidemics.* The earthquakes and the infects have been noticed. Abortions were among the remarka- ble precurfors of this malady. The fame fact is noticed by Diemerbroeck, before the great plague at Nimeguen, in 1635. The fame has been mentioned by the authors he quoted, Foref- tus, Sennertes, and others ; and is afcribed to the tendernefs and debility of the heart and Vifcera. Hence pregnant women firft feel the effects of a ftate of air unfriendly to the fupport of life, and if they are feized with plague, are always its victims. Another phenomenon attending this plague was the death of fifh. This circumftance, with the bad ftate of the water, which is often affected by the peftilential ftate of the elements, and was greatly affected in this period, gave rife to a report that the Jews had poifoned the wells and fprings. The prejudices againft the Jews, which have marked and fcandalized all chriftian coun- tries, except America, were at their height in the reign of Ed- ward the 3d of England, the period under confideration. Thefe prejudices drove legiflators and princes to exercife every fpecies of cruelty upon the Ifraelites, on account of their ufury ; and when the report of their poifoning the water circulated, the pop- ulace in fome places and efpecially in Germany, rofe and affafE- nated multitudes of thefe unfortunate men. The death of animals, particularly of fheep, marked the fame period. In England, 5000 died in one pafture. The ftate of the air and water was fo peftilential that it is averred by hiftorians, the fowls and fifhes had blotches on them. Authorities. Short, on air. vol. r. 165. Knighton, Chron. Pennant's Arctic Zoology p. 67. Townfend's Travels in Spain, vol. 2. 219. Maitland's Hift. of London. Mura- tori, Tom 3. 588 and 594. Univ. Hift. vol 32. 251. Stow's Survey, 478. Mazeray's Ilift. France. Villani, and ma- ny others. * Except eruptions of volcanoes, of which I have no account, at this period except in Iceland in 1340. But my accounts of volcanoes are very imperfect. 14° It miy be remarked that this mortal peftilence raged in Eng- land and France, during peace, or rather during a truce, winch had been concluded between Edward III and the King of France in 1347, and which lafted feven years. Guido, an inhabitant of Avignon, when this malady appeared, and who efcaped death by the favorable procefs of a bubo, re- lates a fact that throws light on this fubject. He fays that the mal- ady was of two kinds—" the firft, and which preceded the other about two months, was a fever, with fpitting of blood," not un- like that which prevailed in the time of Fracaftorius. All who were feized with thefe fymptoms, died in three days. The other kind, which fucceeded the firft, came on with con- tinued fever, carbuncles and abfceffes, in the glands.—This v.as as fatal as the other, except near its.decline, and the patient died in five days. Friend's Hift. Mtd. p. 564. It is remarkable, that the difeafe which is technically called plague, peftis, is always preceded by a fimilar fever. It is in fact theplague in its firflflages, tho it does not exhibit the gland- ular fwellings, which modern phyficians contend are characterif- tic of true plague, and mark a generic or at leaft a fpecific differ- ence between that and any other kind of typhus fever. This fact of a progreffivenefs in the difeafe, annihilates the favorite no- tion of deducing all plagues from infection ; a notion which is bandied about between phyficians and legiflators like a tennis ball, tho unhappily for mankind, infinitely lefs harmlefs. At the clofe of this dreadful period, in 1350, were fevere earth- quakes in Italy. In 1356 a violent fhock in Switzerland, and in Germany, efpecially on the Rhine, which did great injury. To this fucceeded moft violent rains, and famin and peftilence in Germany, with prodigious mortality. Muratori, Tom. 3. part. 2. 594. Brabant efcaped this terrible peftilence and fo did Milan. In 1352 authors relate that 900,000 people in China perifhed by famin. The rainy and humid feafons which introduced the great pefti- lence of 1347-50, were fucceeded by drouth in 1350, a comet i° I35I> with tremendous ftorms, and a meteor which burft 141 with a heavy report. The winter following was fevere, and in 1354 Africa and Cyprus were devoured by locufts. In England prevailed epidemic madnefsin 1355. In 1358 was a fevere winter, followed by an eruption in Ice- land, and a wafting plague in Italy in 1359. According to Bac- cace, Florence loft 100,000 citizens, and Petrarch fays, fcarce- ly ten ef a thoufand furvived. There was a great mortality partic- ularly among child-bed women, and cattle did not efcape. This peftilence alfo became nearly general. In 1361 Milan, which had efcaped in 1348, was feverely afflicted, as was all France, England and Ireland, and it was computed that Scot- land loft one third of its inhabitants. This plague was called the fecond in the reign of Edward III, and it was in time of peace. In this peftilential time, occurred a remarkable ftorm of hail and fnow, in April 1360. The tendency of the elements in fuch periods to generate hail and fnow, is a fact that well deferves confideration. In January 1361, a violent tempeft fpread defolation over Europe. The winter was fevere, and the fummer dry. In March 1362 appeared a comet in the North Eaft, with a vaft co- ma, and an eruption in Iceland. A dearth and difeafes among cattle followed. This laft peftilence differed from that in 1348, in two or three particulars. It raged with moft violence, on mountainous dif- tricts, where the air was pure, and where the plague of 1348 did not prevail. It attacked the nobility and gentry with more vio- lence than the poor ; contrary to the ufual fact; whereas the dif- eafe of 1348 was moft fatal to perfons in the humbler walks of life. Muratori Tom. 3. part a. 600. Liber Niger Saccarii vol. 2. 433. Henry's Hift. Britain vol. 4.194. The comet and volcano of 1362 were followed in 1363 by a winter of extraordinary feverity, which lafted from September to April. The Rhine was covered with ice for ten weeks. The year 1365 was rainy, and the plague carried off 20,000 people in Cologne, and the vicinity. In 1366 an eruption in Iceland deftroyed 70 farms. The fame year was very fickly in England and deaths fudden. 142 In I368 was vifible in March a comet with'a coma, and the crops failed. In this year commenced in England the third great plague in the reign of Edward III.; the reader will note that this was preceded by a fickly year in 1366. The mortal- ity was great, and efpecially about Oxford. The moft fatal year was 1369, and in Ireland the difeafe raged in 1370. I have no particulars of the progrefs of the difeafe on the conti- nent ; but it was very fatal. Murat. vol. 3. 632. Piftorius vol. 1. lib. Niger 435. Maitland's Hift. Lond. Van Trail's Letters on Iceland. In 1373 raged an epidemic madnefs among the lower people in England ; and in 1374 a fimilar diforder prevailed in France and Italy. During peftilential periods, fome general caufe feems to affect the brain in a powerful manner, even in perfons who efcape the plague. In 1374 alfo was an eruption of a volcano in Iceland. There was alfo famin, a violent plague in Italy and fome parts of France. In 1371 there had been a fevere earthquake in the fouth of France. Murat. Tom. 3. 646, 649. In 1379 commenced a great ficknefs in the north of England, which almoft laid wafte the country ; and in 1380 was feen a comet. The difeafe is not defcribed, but it was the forerunner of a moft dreadful plague. Provifions were good and cheap. In 1381 and 2 confiderable earthquakes were felt in England and a fevere peftilence appeared at Avignon in France, which raged for four or five years, depopulating many cities. It pre- vailed in Italy, France, Germany, England, Ireland, Greece, and the Eaft. There was an eruption of Etna in 1381, and the year clofed with great rains. The year 1382 was without winds. The plague was moft fatal to children, and great ravages were made alfo among the friars. In this peftilence Lubec loft 90,000 people. Liber Niger Sac. 441. Short on Air. In 1388 the drouth was fo fevere, that the Rhine was ford- able at Cologne. In 1389 violent tempefts raged in England, with great deftruction ; and in the year following, was an erup- *43 tion of a volcano in Iceland. In modern days, we obferve the fame train of phenomena, evidently depending on one general caufe. In 1389 appeared a fingular meteor or light in the heavens. The year 1389 was remarkable for the death of children in all parts of England. From the phenomena that attended and the difeafes which followed, compared with the order of difeafes in modern days, it appears very probable that this difeafe was a fpecies of Angina, which almoft invariably precedes the plague. In the next year, a deadly plague raged in the north of England. Swarms of gnats and flies marked this period, and fome part? of the continent were overrun with locufts. Piftor. vol. 1. Short on Air. The reader will remark the exceflive drouth preceding the eruption in Iceland and the fiery appearance in the heavens in the year of the tempeft. In thefe phenomena^ nature is nearly uniform. It is a very common event that dyfentery of a malignant type fucceeds the plague. Such was the cafe in England, in 1391, when this difeafe was epidemic and very mortal. A dearth of corn might have contributed to the fame event; but it is often the fact, without any fcarcity of food. An uncommon rednefs of the fun is mentioned in July of 1391, and for fix weeks after, thick vapor or clouds. Perhaps thefe might have been occafioned by the eruption in Iceland, in the preceding year ; as it appears to have been a phenomenon fomewhat fimilar to that which Europe beheld with amazement and terror in 1783.—I have however my fufpicions that while the central fires expel immenfe quantities of burning lava, from volcanoes, they may force through the earth in the adjoining continents, a fubtle vapor, that is iHvifibie, until it is collected and condenfed in the higher regions of the atmofphere. The beginning of the 15th century was marked by a fevere smd defolating peftilence. . The difeafe firft appeared in the laft year or two of the former century. In 1399 the mortality was fuch in Spain, efpecially in Andalufia, that the king was obliged to fufpend the law which reftrained widows from man ying with- r44 in a year after the death of their hufbands. It was preceded by a fevere winter. Mod. Univ. Hift. vol. 20. 353. In 1402-3 and 4 the plague in Iceland carried off multitudes of the inhabitants. Van Troil. In 1400 epidemic and mortal ficknefs prevailed in England. A violent earthquake the fame year in Perfia. In 1401 Flor- ence was nearly difpeopled by the plague. In 1402 in March appeared a comet of a fiery afpect, and coma, which was vifible for three months.* In 1402 a froft fo fevere that the Baltic was paffable for horfes for fix weeks. In 1406 the fea broke into Holland, Zealand and Flanders, with prodigious injury. A plague carried off 30,000 people in London ; and a comet the fame year. The winters following were fo fevere that moft birds died. In Sept. there were great floods from rain. In 1408 there was an eruption of Etna and deep fnow. Piftorius, Germ. Script, vol. 1. Short on Air. Maitland's Hift. Lond. The fummer of 1406, when the plague raged in London, was clofe, moift and foutherly weather. In 1411 the dyfentery carried off 14000 people in Bour- deaux, but I have no account of the feafons. The plague ra- ged in Aquitain and Gafcoigne with great mortality. In 1412, there were uncommon tides in the Thames. In 1414 a comet, and in 1416 an eruption of fire from a volcano in Iceland, pre- ceded by great fnow. In 1421, according to fome authors, happened the dreadful inundation in Holland, which formed the Zuyder Sea. In 142 2 there was an eruption of fire in Iceland, and a fevere winter followed. The fame year, the plague raged in Poland. From thefe phenomena, I fufpect the approach of a comet, but have no account of one. In 1426 a comet, an exceffively hot fummer, and a violent earthquake which overturned twenty cities in Catalonia, in Spain, and was felt in moft parts of Europe. In 1427 the feafoni * According to Liber Niger Saccarii, this was in 1401, and this is moft probably correct. The period of this comet is 343 years and wc fhall find it under the year 1744. r45 were rainy, the winter mild, a dearth and famin followed, and the plague in Dantzick. Epidemics prevailed in England, and the year following, the plague. In 1430 happened a general earthquake—in 1432 a great in- undation in Germany—in 1433 a comet was vifible for three months, in the fouth, and the winter following was terribly fe- vere. The froft began in the laft week in November and lafted till the middle of February. Piftorius Germ. Script vol. 1. Short, vol. r. Liber Niger Sac. vol. 2. In 1436 there was an eruption of a volcano in Iceland and a fevere winter. An epidemic fever prevailed in Venice, which was attributed to the ufe of ftagnant water. In 1438 and 9 violent ftorms and great rains injured the corn and a dearth enfued. A comet in 1439 and a hard winter followed. To thefe phenomena fucceeded in 1440 a feries of diftreffing epidemics, fevere coughs, fmall-pox, fevers and dyf- entery, which proved exceedingly fatal. Short vol. 1. Piftorius vol. 1. In 1443 Bohemia, Hungary, and Poland were terribly in- jured by an earthquake. In 1444 there was eruption of Etna and Lipari, and the explofion was repeated in 1446 and 7. An epidemic prevailed in 1445, which fuddenly ended life, but it is not defcribed. In January 1449 was feen a comet. This year the plague raged in Italy and in 1450 famin and plague. In Milan perifhed 60,000 people. Muratori vol. 13. Short vol. 1. This plague of 1450 is faid to have arifen in Afia, and after- wards fpread over Italy, Germany, France and Spain, leaving alive fcarcely a third of the human race. In 1455 appeared a comet and another in 1456. In this lat- ter year, Italy was violently fhaken by an earthquake, and 40,000 people perifhed.—Piftorius places the earthquake in 1457, and fays it demolifhed 40 towns, and deftroyed 60,000 lives. In 1459 a plague began in July and raged fix months in Italy. Piftorius vql. 1. 375. Muratori Tom. 5- p- 5°» short voL x< T 146 It will be obferved, in this period and in many others, that the plague is not mentioned under the year of the earthquake. Modern obfervations explain the progrefs of peftilence, which is moft ufual, viz. meafles, catarrh, angina, and other malig- nant complaints preceding the crifis of the peftilential ftate of air, or plague. And we find almoft invariably fome of thefe difeafes to be epidemic, even before the comet, earthquakes and erup- tions of volcanoes, altho the moft violent form of the peftilence does not always appear till a year or two after thofe phenomena. There is alfo a difference, in the times of the appearance of the plague in various countries. In Egypt, the peftilence ufually ap- pears firft, and is cotemporary with the comet, or nearly fo ; and the fame year, when the plague rages in Egypt, we find an- ginas and other malignant difeafes prevailing in Europe and America, in northern latitudes. This difference in time evin-. ces the power of local caufes, in aiding the progrefs of the epjj demic conftitution of air, and which produce the moft violent difeafes in Egypt, one, two or three years, previous to their ap- pearance in cooler latitudes. But it will almoft always be found true, that the commencement of a feries of epidemics is nearly at the fame time in all parts of the world ; the precurfors of the plague being nearly cotemporary in different countries ; altho the peftilential conftitution or general contagion arrives to its crifis much fooner in Egypt, Smyrna and Conftantinople, than in places lefs expofed to the influence of local caufes of difeafe, In 1465 peftilence again appeared in Italy, but I have no particulars. In 1467 a comet, and a mild winter is recorded ; a remarkable fact, and the fecond inftance I have found in hif- tory. Indeed fo uniform are hard winters during the approach of comets, that the accounts of exceptions are to be fufpected of inaccuracy in point of time. In 1468 a moft deadly plague raged in Parma of which Short gives a particular defqription from Rolandus Capellatus. Short, vol. 1. 194. Muratori, vol. 13. Edit. Milan. Piftorius, Germ. Script, vol. 2. In 1471 the winter was rigorous and ftormy. In 1472 ap- peared three comets ; two of them of diftinguifhed magnitude. In 1473 moft exceflive heat and drouth, and authors relate that H7 the woods took fire by the heat of the fun. This drouth con- tinued three years—--all fmall rivers were dried up—the Danube was fordable in Hungary. In 1475 and 1476 appeared thofe enormous fwarms of locufts, which always denote a ftate of air highly peftilential, and ravaged Hungary and Poland. In 1474 earthquakes were felt in Germany. In 1475 an eruption of a volcano in Iceland. Thefe phenomena, in this period, as ufual, introduced moft terrible peftilence, which began in 1472 and arrived to its height in 1477. It raged in Italy, Germany, France and England, and how much more extenfively, my authorities do not inform me. It prevailed feveral years, with incredible mortality. In Paris perifhed 40,000 ; a large number for the population at that time. In England the number of deaths was not eftimated ; but authors relate that fifteen years of civil war did not carry off one third of the number. This year 1477 was exceffively hot. In 1478 innumerable locufts overran Italy. In 1478 and 9 the plague in England repeated its ravages ; beginning like that of 1348, in autumn, raging through the winter until the next autumn. Piftorius, vol. 2. 754. Muratori, vol. 13. Short, vol. 1. Maitland's Hift. London. Fracaftorius de Contagione, 136. Fernelius de morbis Peftilentibus. In 1480 the winter was fevere. In 1481 and 3, a moft deadly plague infefted Italy and Ger- many. Muratori, vol. 13. Piftorius, vol. 2. 875. In 1482 a fpecies of pleurify was epidemic in Italy. Fracaftor. p. 182. In 1484 the winter was fevere. In 1483 or 5 appeared in England a new fpecies of the plague called Sudor Anglicus, or fweating ficknefs of the Englifh, be- caufe it was fuppofed to attack none but Englifhmen. This however was a miftake; for the fame difeafe, at different times, appeared in Ireland, Germany, Sweden and Holland. In the life of Erafmus, it is faid to have appeared firft in 1483, and to have returned in 1485. John Kaye, or Caius, a cotemporary phyfician, fays, it firft appeared in 1485 in the 148 Duke.of Richmond's army, on his landing at Milford Haven* in Wales. But on all hands it is agreed to have had its origin in England, and to haye been a fpecies of plague. It is called " novum peftilentias genus," a new kind of peftilence ; and inftead of being peculiar to England or Englishmen, " a Brit- annis exortum, incredibili celeritate per orbem longe lateque divagatum eft ;" it originated in Britain, and with incredible ra- pidity fpread far and wide over the earth. Life of Erafmus, 347. Friend's Hift. Med. 566. Sir Thomas More, in a letter to Erafmus, declares this dif- eafe in London, Oxford and Cambridge to have been more dangerous than a battle. " Minus periculi in acie, quam in urbe effe." The fummer of 1485 was exceffively rainy, and an inunda- tion of the Severn made great havoc with men and cattle. This difeafe attacked perfons fuddenly, with a fenfation like that of hot vapor running through the part affected. To this fucceeded internal heat, unquenchable thirft, and profufe fweat- iag, which often carried off the patient in two or three hours. The violence of the attack was paft in 15 hours, and in 24 hours the patient was confidered to be out of danger. It was moft fatal to perfons in high health and eafy condition of life. It was attended with moft of the fymptoms which characterize the plague—anxiety, reftleffnefs, violent pain in the head, de- lirium and exceflive drowfinefs. See the life of John Caius, in Aikins' Biographical Me- moirs of Medicine, p. 120, alfo Friend's Hift. Phyf. This was a peftilential period, for the plague infefted Italy and Germany in 1483, and Denmark in 1484. And it will be found on examination, that when the fweating ficknefs raged in any part of Europe, that or fome other peftilential difeafe, was in other countries. During the prevalence of this fbrm of the plague in England, at this period, Denmark loft nearly one half of its inhabitants by the common plague ; which raged ter- ribly for two years. The author of the Traite de la Pefte, page 23, remarks, " That until the 15th century the plague exhibited the fame character; but then " its accidents degenerated," or rather it 149 reigned a new malady, which, under different external appear ances, committed fimilar deftruction on the human body. It did not any longer fhow itfelf by buboes, carbuncles and pim- ples ; nor by any of the eruptions which the heat of the vifcera pufhes out; nor was the fkin withered by the parching drynefs which accompanies the carbuncular fpots ; on the other hand, the fkin was inundated by torrents of fweat, which feemed to be poured from the whole body, the vifcera were dried, and the heat which diflipated the fluids, feemed to diforder all the laws of the animal economy. About the middle of the 16th century, the plague refumed its former character, but the fymptoms fomewhat varied and lighter." The fweating plague at firft attacked none but Engliflimen. Even Scotchmen efcaped, in foreign countries, where Englifli- men were feized. Foreigners in England efcaped. This how- ever was on its firft invafion in 1485—for, in fubfequent years, it fpread over other countries. But the fact of its feizing only Englifhmen at firft, is precifely analagous to what has happened on many other occafions, in other countries. It recurred in England in 1506, 1518, 1528 and 1551. In 1491 appeared a comet, the feafon was very wet, an epi- demic fwept away cattle, and a famin afflicted Ireland. A fe- vere winter is noted in 1493. Short, vol. 1. Smith's Cork, page 30. In 1495 and 6 the plague raged in Portugal. Hift. of Portugal by Oforio. In 1496 an epidemic leprofy prevailed in Germany, which covered the body with ulcers from head to foot. Piftorius, vol. 2. In 1498 the fummer was very dry. In 1500 a tempeft in Rome did great injury, a comet was vifible in Capricorn, an eruption of Vefuvius, and a mortal plague raged which carried off in London 30,000 people. The king for fafety retired to Calais. Maidand arranges this plague under the year 1499. This peftilence was preceded by an abundance of provifions. Short, vol. 1. Maitland's Hift. London. It is a current opinion that the venereal difeafe was imported tiltO Europe by the firft adventurers to America, with Colum- bus ; and that it gradually fpread in Spain ; from whence it was carried into Italy by fome of the foldiers, who were in the fiege of Naples in 1494 ; thence it was propagated rapidly through- out Europe. This fubject will be hereafter confidered. It is however remarkable, that an epidemic leprofy fpread over Ger- many, about the fame time, which feems to indicate an unufual tendency in the human body to ulcerous and fcorbutic complaints. tan agues were fatal, and malignant fevers, in others. Violent tempefts and inundations are mentioned, this year and the laft. In 1558 died Charles V. emperor of Germany. Short vol. 1. Van Swieten vol. 16. p. 23. Maitland's Hift. Lond. Univ. Hift. vol. 27.373. In 1560 a comet, and a dearth of corn in England. In 1562 and 3 the plague fpread over Europe. It broke out in 1562 among the Englifh foldiers, who were fent to garrifon New-Haven in France. The next year it raged in London and carried off 20,000 of its inhabitants. Authors fay, the fold- iers from New-Haven introduced it into London ; but who in- troduced it into New-Haven, we are not informed. The truth is, this terrible difeafe appeared in moft parts of Europe about the fame time. In Frankfort, Nuremberg, Mag- deburgh, Hamburgh, Dantzick, and in the vandalic maritime towns, Wifniar, Lubick, Roftock and others, perifhed by com- putation 300,000 perfons in the year 1563.—This difeafe alfo raged in winter, for Thuanus mentions the death of Caftalion, a literary character of that age, by the plague at Bafle in January. This year was remarkable alfo for earthquakes. In Sept* was a violent one in England, efpecially in Lincoln and other northern parts. In January the river Thames was agitated by preternatural fluxes of the tides, which forced back the natural tides, three times. In winter, fevere cold rendered that river paffable as a highway. The fame year earthquakes were felt in Illyrica, and Dalma- tia, and Catana fuffered a great lofs of lives. In 1564a comet appeared, and remarkable northern lights, or meteors, and a deftructive inundation of the Thames. Short vol. 1. Maitland's Hift. Lond. Thuanus. Strype's Life of Archbiftiop Parker, 131. In 1564 epidemic quinfies were very mortal, and in fome places, the fpotted fever or the plague.—In winter came on as fevere a froft for two months as was ever known. This epidemic quinfy was a fpecies of angina maligna, and fa^ tal as the plague. It fpread over Europe. In 1565 France was afflicted by peftilential epidemics> in ?58 Which bleeding and purging were fatal. The next year appeared the plague hi Lyons.—Charles IX. demanded of the phyficians the beft mode of treatment, and they all decided againft vene- fection.__One fourth of the inhabitants of France perifhed. In 1566 the fpring was rainy and the harveft dry. The Hungarian fever broke out in the Emperor Maximilian's army, and as authors affirm, the foldiers, when difbanded, fpread it all over Europe, with great mortality. This difeafe invaded the patient at 3 o'clock in the afternoon, with flight cold and fhiver- ering for about fifteen minutes. This was followed by intenfe heat, and intolerable pain in the head, mouth and ftomach, fo that the flighteft touch of the bed clothes, made the fick utter fhrieks : The pain in the mouth and ftomach being the pathog- nomonic fymptoms of the difeafe.—The thirft was unquencha- ble, and a longing for Wine, which was fatal, if taken. The tongue was dry and lips chopt. Delirium came on the third day. A critical loofenefs and deafnefs were favorable—Swel- lings behind the ears were frequent. The moft miferable crifis was, tubercles on the top of the foot, which, if neglected, ended in mortification. Many fuffered amputation. Spots, like flea bites, appeared on the body, and if livid or black, they were fatal fymptoms. Copious bleeding, on the firft feizurei was, of all remedies, the moft fuccefsful. Skenkius' p. 770. Short vol. 1. In the year 1567 was an eruption of Etna, and in Tercera, one of the Azores, fire burft from a lake on the top of a hill, and the water releafed from its bed, rufhed down and fwept away part of a fettlement below. In 1568 a fpotted fever raged in Paris, in which proftration of ftrength rendered bleeding fatal. The winter of 1567 was very fevere, and the fummer exceffively dry. In 1569 appeared a comet.—The fpotted fever in this year became epidemic in Europe, raging for three years with great deftruction. The plague was in London. Short remarks that this fpotted fever " in feveral places turned to the plague, and where the plague raged, it turned to this fever."—Indeed this fpotted fever was a milder form of the peftilence, raging as it '59 ufually does, for fome time, before the glandular plague appears In this period, it was the herald to announce one of the moft general plagues that Europe ever knew. The petechial fever prevailed principally from 1569 to 1574, interfperfed with the real plague, in a few places; and the real peftis followed it, with mortal rage, and prevailed for three or four years. In 1570 a moft dreadful earthquake in Chili, S. America, deftroyed many villages and buried the inhabitants in their ruins. This is the firft occafion I have of introducing America in this hiftory. UUoa b. 8. ch. 7. Thuanus, whofe authority is very refpectable, and who was cotemporary with this period, relates that in 1570 the dikes in Holland were broken by a fwell of the ocean, and that 400,000 people were overwhelmed in the floods. He fays further that fimilar phenomena were obferved, that year, in different places over the whole world. Reggio, Florence, Venice and Modena felt fevere fhocks of earthquake in 1571, and Ferara was laid in ruins. The fummers of 1570 and 71 were moift and warm ; and in general the feafons were fimilar for the two fucceeding years. The winters were rigorous- Fluxes, meafles, worms and femi- tertians were epidemic in many places. In 1572 appeared a comet or neW ftar, very bright and clear, larger than Jupiter, in the conftellation of Cafliopeia, behind her chair. It was ftationary for 16 months and by degrees evanifhed. The winter fucceding was remarkable for hard ft oft and deep fnow. The author of Obfervations de Phyfique et de Medicine, fays, that all maladies in France in 1572 turned to epilepfy and palfy. This year the plague raged in Poland ; and_at Bafle a malig- nant fever, chiefly fatal to men of robuft conftitution. In 1574 the petechial fever, which had fpread mortality over Europe, efpecially in Italy and Spain, began to change into the ufual form of the plague. This difeafe made its appearance in London, in a fmall degree, in October and November of this year. In 1575 the plague appeared in many parts of Europe, and i6o raged with incredible mortality for three years. It was reported^ in Italy to have been Imported into Verona and Venice, from Trent. Such was the current vulgar opinion. But men of fci- ence held the difeafe to be generated in cities from the filthinefs of private dwellings, and not to be produced by the pofition of the ftars or malignant conftitution of the air. The truth was, the difeafe in Italy firft appeared in Trent, an Inland town, far from the fea—another inftance in which the advocates of importation from Africa or the Levant are filenced. Philofophy difdains to look abroad for the caufe of an epidemic, when the ftrongeft of all caufes exift in the place. Trent is fituated in a valley, on the bank of the Adige, a river which often overflows the adjacent low lands; and after the flood re- cedes, the place is fometimes fo fickly that the people are com- pelled to retire to the neighboring hills. Strong local caufes therefore account for the firfl appearance of the plague in that city. The general contagion of the atmofphere, which had produced fpotted fevers and other deadly difeafes all over Eu- rope for four years preceding, was aided by the local unhealthi- nefs of Trent, and here appeared firft, the crifis of the pefti- lence, or plague. See the defcription of that country in Zim- merman on Air. The difeafe almoft depopulated Trent in 1575, and became mortal in the neighboring Venetian territories. This mortality however was only the forerunner of greater evils. The difeafe indeed fubfided in winter, and the people fuppofed its violence to be paft. They might have known otherwife, had they atten- ded t© the progreffivenefs of the malady, and the certain indi- cations of its increafe. In 1576 the difeafe appeared in Venice ; and as it carried off a few people at firft, in fcattered fituations, opinions were, as ufual in all fach cafes, divided as to the nature of the diftem- per. In this ftate of the public mind, two eminent phyficians, Mercuriale of Forli, and Capavacca of Padua, undertook to affert the difeafe not to be peftilential. The fenate, obfening the controverfy among the Venetian phyficians, as to the nature pf the diftemper, liftened to the two foreigners, who declared i6i they could cure it, and put a flop to the removal of the difeafed from the city. By this means, fays the hiftorian, the diftemper was obvioufly increafed; and it raged with terrible fury, till it carried off 70,000 of the citizens, with fifty-feven valuable phyficians and furgeons. The two foreign phyficians were dif- miffed, with applaufes for having preferred the good of Venice to their perfonal fafety. This account from Thuanus deferves particular notice. We here fee the fame doubts about the nature of the difeafe on its firft appearance, which prevail in all fimilar cafes—as in Mar- feilles in 1720—in London in 1665—and in America, with refpect to the yellow fever, which is only another form of plague. The fource of all thefe doubts and controverfies, which have fo often embarraffed the citizens and difgraced the faculty, is, the progrefflvenefs of the peftilence. The malignant difeafe? preceding, Hide into the glandular plague fo gradually, that phy- ficians themfelves do not know precifely when the diftemper fhould lofe the name of malignant fever and take that of plague, Sydenham honeftly confeffes that, in 1665, he did not know whether the malignant difeafe which appeared in May and be- came epidemic, juft before the plague, was the real plague or not. And the truth is, that the difeafe often affails people, in a few fcattering cafes, at the beginning of a plague, with a mor? tality equal to the true peftis, and without the diftinctive marks of plague, the glandular tumors. Thefe facts will hereafter, with careful obfervation, obviate all controverfies at the beginning of peftilential difeafes; and they will decide infallibly all queftions relative to the domeftic or foreign origin of fuch maladies. This peftilence was feverely felt in Padua, Milan, Cremona. and Pavia. Vicenza, which efcaped this year, was vifited the next, with equal fe verity. Dr. Mead is puzzled to know why Vicenza, which lies be- tween Verona andPadua? fhould efcape the plague, in the year when both thofe cities were infefted; and yet the next year, fhould fuffer equally with her neighbors, when they were exempjt from the calamity. He finds fome difficulty in accounting for W 'l62 the conveyance of the infeaion from one to another, without communicating it to the intervening city. This fubject will be confidered in a fubfequent fection ; I will only here remark, that nothing is fo fatal to truth and fcience, as for a man of popular talents to elpbufe an erroneous theory, and then ftrive to bend facts to its fupport. See Thuanus, lib. 62. Shenkius,, 756. Short, vol. 1. In 1575 multitudes of flies and beetles were found in Eng- land, and in 1576 an earthquake was experienced. In November 1577 appeared a comet of furprifing magni- tude, with a long coma—and moft terrible tempefts accompani- ed its approach. In 1578 another comet, and in 1579 an erup- tion of Etna. In 1578 were earthquakes in England. Short, vol. 1. In the great peftilence of the preceding ten years, not only Europe, but Afia was laid wafte. So general and fevere was the difeafe that the operations of war, in the Turkifh empire, were fufpended. Meflina in Sicily loft 40,000 inhabitants—and Europe muft have loft in ten years, by the peftilence under the various forms it affumed, one third, or more probably one half her people. In this period we fee all the extraordinary operations of nature united. Comets, earthquakes, in Europe and S. America tem- pefts, volcanoes, unufual animals, exceflive floods from rain or an extraordinary intumefcence of the ocean all mark an extreme agit- ation or diforder of the elements.—The vaft comet of 1577, the year when the plague was at its height, was calculated to ap- proach within 840,000 miles of the earth. Upon the Newton- ian principles of the power of attraction, the influence of that body on the earth muft have been prodigious. Encyclop. art. Aftronomy. In this year appeared in Moravia a new difeafe, evidently dif- tinct in its fymptoms from any known malady, and which Thu- anus has defcribed. This alfo was the year in which a fudden difeafe feized the court and attendants at the Oxford aflizes in England. Early in July, while the court was fitting, " there arofe, fays Stowe, amidft the people fuch a damp that almoft all were fmothered— ifj3 very few efcaped, that were not taken at that inftant. The ju- rors died prefently—after which Robert Bell, Lord Chief Ba- ron. There died in Oxford 300 perfons—and fickened there, but died elfewhere, more than 200 from the 6th to the 12th of July. After which died not one of that ficknefs, for one of them infected not another, nor died thereof any one woman or child." Chronicle, p. 681. This fudden cataftrophe is afcribed to a damp or vapor. But there is no need of reforting to fuch a caufe. The atmofphere, during the period under confideration, was not furniflied with the power of fupporting animal life, in as ample a manner as it ufually is.—This is evident, from the univerfality of mortal epi- demics. In'this ftate of the atmofphere, a multitude, crouded into a court room, in the hot month of July, muft fpeedily def- troy all the refpirable air, and death muft enfue. That the prin- cipal caufe was not only local, but fudden, is deraonftrated by the circumftance, that no infection accompanied the difeafed. Had the caufe of their illnefs been long ia operation, it would have produced in the body that fpecies of poifon, which is nox- ious to perfons in health. Perfons, fuddenly deprived of life, as by damps in wells or the fumes of charcoal, communicate no infection. It is fuggefted by fome writers, that this difeafe was occafion- ed by an infected prifoner, who was brought from jail into court; but Stowe does not mention this circumftance. And it is poflible the cataftrophe might have been owing to a fudden difcharge of mephitic vapor. Scarcely had the laft period of peftilence come to a cloft, when another feries of maladies fucceeded, and nearly in the or- der of thofe laft defcribed. In 1580 appeared a comet on the 10th of October which was vifible for two months, The preceding fummer was very moift and rainy, and about the rifing of the dog-ftar, came on a cold dry north wind. In June began an epidemic catarrh in Sicily, which fpread over Europe. In July, it was in Italy ; in Au- guft, in Venice and Conftantinople ; in September, it extended over Hungary, Bohemia and Saxony; in October, on the Bal- X&4 .tjc; in November, in Norway and in December, in Sweden, Poland and Ruffia.—Its fymptoms were nearly the fame, as in this country, but the difeafe was more violent and fatal.—In Rome, died of it 4000 people—in Lubec, 8000 ; at Ham- burgh, 3000 ; and multitudes in other places. It appears to have been attended with more fever than in ordinary cafes—Thr fever was continual for four or five days, with a pain in the head, ftraithefs of the breaft and cough—it terminated ib profufe fweating.—In general bleeding and purging were found to be prejudicial. Rivcrius, lib. 17. In this year and about the time, when the catarrh had over- fpread Europe, broke out in Grand Cairo, one of the moft def- olating plagues ever known. Profper Alpinus, who lived in that age, reports the number of deaths, from November 1580* to July 1581 to have been 500,000. It will be found on ex- amination that the plague, in a feries of peftilential and epidemic difeafes, appears in Egypt, before it does in Europe and Amer- ica, and is nearly cotemporary with the catarrh, angina or other precurfor of the peftilence in more northern latitudes. This fact deferves notice. The plague which followed the catarrh in Europe, did not appear in many places, perhaps in none except in France, in the year 1580—In northern latitudes, the malig- nity of the epidemic conftitution does not appear, till the fecond or third year, after its commencement in catarrh or meafles. In Paris however the plague raged in 1580, the fame year it appeared in Egypt, and carried off 40,000 people, moftly of the poorer fort ; and at the fame time, it prevailed in many of the neighboring towns, efpecially, fays Thuanus, " at Laon in Vermandois, which city is in a pofition expofed to a hot fun, in which died 6000." The hiftorian further remarks, that the " crops that year were plentiful, and the flcy ferene ; fo that it was thought the difeafe was produced rather by the influence of the ftars, ab aftrorum impreflione, than by the malignity of a corrupt air." This is another proof that a ftate of air, as defcribed by Hip- pocrates, is pot always the caufe of peftilence. *6$ Altho this malady broke out in France in 1580, yet it had been preceeded by the catarrh. The hiftorian remarks, that the catarrh was not fo much dreaded for its mortality, tho many died of it, as for the aftonifhing rapidity with which the contagion fipread from place to place. It feized the lower fpine of the back with a chill, horrore ; to this fucceeded gravedo, a dull pain ia the head; and univerfal languor or debility, refolvens membra, loofening or unhinging the joints. If the crifis was not favora- ble in five days, the difeafe terminated in a fatfn fever. See Thuanus and Riverius.alfo lib. 17. In 1580 confiderable earthquakes were felt in Belgium, at Cologne and about the Mediterranean. The fame fkocks were felt in various parts of England, but! Short places them under the following year. The German fea was agitated, and a great fwel- ling of its waters was obferved. See Thuanus, lib. 71, 72. Short, vol. 1. p. 260. In 1580 alfo, the marfhes in Effex, and fome parts of Kent in England, were laid wafte by mice, which were fo numerous as to deftroy the herbage, and a murrain among cattle fucceeded. In this year was iffued a proclamation of Queen Elizabeth, upon the reprefentation of the Mayor and Aldermen of Lon- don, prohibiting any new houfe to be built within three miles of* the gates of the city, and more than one family to refide in a houfe. The reafons afligned for the prohibition are connected with this fubject. The increafe of London had long been con- fidered as an evil, by fwelling the head too large for the body, and feveral attempts had been made to reftrain the increafe. The refort of people to the city from the country was held to be prejudical to agriculture. But the proclamation ftates further, that " fuch great multi- tudes of people, brought to inhabit in fmall rooms, whereof a great part are very poor, yea fuch as muft live by begging, or by Worfe means, and they heaped together, and in a fort, fmoth- ered with many families of children and fervants, in one houfe or fmall tenement, it muft needs follow, if any plague or popu- lar ficknefs fhould, by God's permiffion, enter amongft thofe multitudes, that the fame would not only fpread itfelf, and invade 166 the whole city and confines, but a great mortality would enfue the fame, and the infection be difperfed through all other parts of the realm." In this paper, we obferve fome powerful caufes of peftilence in London to be explained—and events fhowed how little good was done by the interference of authority with private rights, and an attempt to check, by pofitive prohibitions, the natural growth of towns. This proclamation, like all which had pre- ceded it, was ufellTs. The city increafed, and the plague con- tinued to ravage it, until the good providence of God arrefted the evil, by a general conflagration, apd men had become wife enough, to build large, airy houfes, and keep them clean. Maitland's Hiftory of London. In 1582 a remarkable tempeft is mentioned, and a comet in May. A fevere earthquake was felt in South-America, and a fmall city near Lima was deftroyed. Ulloa's Voyage, vol. 2. b. 7. In 1583 feveral concuflions of the earth were experienced in England, and the plague appeared in London. At the fame time it appeared in Germany or Holland ; as Diemerbroeck mentions this as a peftilential year. The following winter was fevere. In Rome there was a famin. Maitland's Hift. Lond. Short, vol. I. In 1585 in fpring appeared very malignant pleurifies. In 1586 Thrace was overrun with locufts, and the plague raged in Hungary, Auftria and Turkey. A comet appeared in each of thefe years, and in 1586 Lima in South-America was nearly ruined by an earthquake. See Ulloa, from whom my accounts of earthquakes in Spanifh America, are all taken. In 1587 a very cold fpring, but a plentiful year in moft coun- tries. The plague raged in Flanders, which was almoft depopu- lated by difeafe, war and famin. In fome parts, the wild beafts took poffeflion of the houfes. Dogs ran mad, and did no fmall mifchief, and fields were covered with weeds and bufhes. The catarrh appeared in England, this year, but how extenfively, I am not informed. An eruption of fire in Iceland is recorded under the fame year. 167 In 1589 the Englifh fleet, returned from Portugal, with the Hungarian fever, fays Short, and introduced it into England. What an influence have names, and what mifchief is done by ignorance and falfe philofophy ! The Hungarian fever ! As tho this fever had been a native of a particular foil, and tranfplanted from country to country, like a fruit-tree. Names are not al- ways harmlefs. The name, Sudor Anglicus, given to the fweat- ing plague, becaufe it appeared firft in England and was at firft peculiar to Englifhmen, has led the moderns to fuppofe, the dif- eafe to have been limited to England or to Englifhmen, altho it repeatedly fpread over all Europe. In the fame way, the infect which injures wheat in America, was ignorantly called the Hef- fian fly, and altho the animal was never known in Gesmany, yet people believe, that, like yellow fever, it was imported. It is thus that ignorance gives currency to an improper name, and the name in turn aflifts to propagate and perpetuate an error. The truth, in regard to difeafes, is, that they often affume peculiar fymptoms ; fuch as are not ufual. Thefe are not prop- erly new difeafes, but modifications of common fever, proceed- ing from the infinite variety of that caufe of ficknefs, which I denominate general contagion, and which Sydenham called the Epidemic Conftitution of the air. This or other caufes are per- petually diverfifying the fymptoms of difeafes ; fo that phyficians are often at a lofs whether to call a difeafe by an old or new name. Wherever the peculiar caufes firfl exift, there will the peculiar fymptoms of difeafe firft appear—and when fimilar caufes e#ift in other places, the fame fymptoms will attend the difeafe. In 1590 multitudes of people perifhed by famin. A comet approached the fyftem, the winter was cold, a violent earth- quake convulfcd Hungary, Bohemia and Vienna; near the lat- ter place, the earth emitted an offenfive fmell. The drouth was extreme. The Azores were fhaken by an earthquake, and a tempeft in September threatened to overwhelm them in mafs. In 1591 univerfal catarrh in Europe was a prelude to moft deftructive peftilence. It is fingular alfo that the plague broke out in Narva and Revel, in Livonia, on the gulf of Finland, in the 59th degree of latitude, and raged through the fucce uir\± 168 (Eold winter. Six thoufand perfons perifhed in Revel. As to )ts origin, the great Thuanus could not decide whether it was *' a belli incommoditatibus, five cseli inclementia," from the dif- treffes of war, or intemperature of the air. There could have been no fufpicion of a foreign origin. Thuanus, lib. loo. Cotemporary with the catarrh was a malignant fpotted fever in Trent. A diftreffing famin caufed a great mortality in Italy., In 1591 the plague began tofhow itfelf in Italy, but attended with peculiar fymptoms. A fever, little infectious, feized the head, inducing delirium, and in many patients, was attended with fluxes and flatulent bowels. It terminated fatally on the tenth day. The remedy was bleeding " Secta vena capitis, qua? in brachio eft, aliifque a capite manantibus," fays Thuanus. It attacked chiefly men between the ages of 30 and 50 ; but was fatal to few women. It raged in Umbria, Tufcany, Romagne and Lombardy, fweeping away, in fome towns, almoft every man. From Auguft to Auguft, it was computed that 60,009 perfons perifhed. Thuanus, lib. 102. In 1592 the petechial fever fpread over Florence, with a ma- lignity that entitled it to the name of plague. It was moft fatal to the nobles. In England the drouth in this and the former fummer was extreme. The Thames was fordable at London. The plague appeared in Shropfhire in the weft, and carried off 18,000 cit- izens in London. Perfia fuffered much by an earthquake in the fame year. Short, vol 1. Sims on Epid. Mem. Med. Soc vol. 1. Maitland's Lond. In the fame year a furious peftilence prevailed in Candia. I; appealed in fpring, increafed till July and then abated. On its firft appearance, all infected and fufpected perfons were removed to a diftant hofpital, but without effect. The difeafe continued to fpread—a proof that it was an epidemic. In September, it was fuppofed to be extinguifhed ; but in October, it broke out with frefh violence, and the difeafed were confined to their houfes—a ufeLfs and pernicious regulation. The city bft 30,000 inhabitants. 169 In 1594 was a fevere winter. The years 1594, 5 and flr were very rainy in England and Germany. Crops failed, and in Hungary, the famin was extreme. In 1596 appeared a comet. Violent earthquakes fhook dif- ferent countries, and feveral cities in Japan were fwallowed up. In 1596 and 7 prevailed in Cologne, Weftphalia and other parts of Germany, a fingular difeafe, which authors afcribe to the famin which had preceded. It was a malignant fever, which was attended with convulfions and raving madnefs, or delirium. Sometimes the convulfions were attended with little or no fever. The patient was contracted into a knot or ball by the violence of the convulfions, or extended to full length, like a dead body— fometimes the extenfion of the body was fucceeded by a con- traction in the fame paroxifm. The particulars refpecting this difeafe do not fall within the plan of this hiftory, but may be found in Short, vol. 1. In 1597 appeared a comet, and the fame year the catarrh was again epidemic. Malignant fevers, accompanied with worms in youth, were predominant alfo, and the plague was in Juliers and Geneva. A dearth in England. The winter of 1597 was fe- vere, as was that of 1599. The fummers of 1598 and 99 were remarkably dry, and fwarms of fleas, gnats and flies abounded. Tertians, with pe- techia?, were frequent, and continual fevers which yielded to bleeding and purging, or went off with a bilious diarrhea.-—« Small-pox and meafles were alfo epidemic. Thefe difeafes, as ufual, were the precurfors of a very dif- treffing plague, which, in the autumn of 1598, raged in Lon- don, Litchfield, Leicefter and other places in England. It even broke out in the fmall towns in Wales and the northern counties, as in Kendal in Cumberland, where died 2500—in Richmond, where died 2200—at Carlifle which loft 1196 in- habitants ; and at Percrith which loft 2266. See Camden's Britannia. In 1598 Pegu, in Afia, was depopulated by famin, and Con- ftantinople was almoft ftripped of its inhabitants by the plague, X 170 Seventeen princeffes, fifters of the Sultan, Mahomet III. died in one day. To arreft the progrefs of this mortality, cannon were fired and aromatics burnt in all parts of the city ; but with what fuccefs the hiftorian does not inform us. Hiftory of the Turkifli Empire. In Italy an inundation of the Tyber injured Rome. In 1599 the fpring was cold and dry; the fummer hot and rainy, with great floods. A very mortal diftemper raged among cattle in Italy. In Spain and Lifbon died 70,000 people of the plague. In fome places, a fatal dyfentery prevailed. Short, vol. 1. £>ims on F.pW. *7i SECTION VI. iliftorical view of Peftilential Epidemics from the year 1600 to the clofe of the year I 700. r v 'i X HE year 1600 was remarkable for peftilence in almoft every part of Europe. Spain, where the difeafe was fatal the year before, was this year almoft depopulated. There raged throughout Europe, a peftilential, mortal cholic which deftroyed the lives of all whom it feized, within four days. The patient, as foon as he was feized, became fenfelefs—the hair fell from his head—a livid puftule arofe on the nofe, which confumed it—■ the extremities became cold and mortified. In Florence a terrible earthquake deftroyed many buildings. The winter of 1600 was very cold. In the fummer of 160I there was a fevere drouth of four or five months ; and a violent dyfentery followed, with double tertians and continual fevers. The plague raged in Portugal, attended with black round worms. At Chriftmas, there was an earthquake in England. The fame year there was an earthquake at Arequipa, in Peru, accompa- nied by an eruption of a volcano. In 1602 a cold and dry fummer and winter, the catarrh Was epidemic, and acute fevers prevalent. Thefe difeafes and phe- nomena accompanied a feries of calamities in all parts of Europe. The famin that marked this period, for a feries of years, ex- ceeded in extent and feverity, what had been before recorded. Famins are ufually local; bat in the prefent inftance, there was a failure of crops for feveral years, in almoft every part of Eu- rope ; while the plague committed moft defolating ravages. In Mufcovy the famin raged for three years at the beginning of the century under confideration, attended with the plague. Parents devoured their dying children ; cats, rats and every un- t?l clean thing was ufed to fuftain life. All the ties of nature and morality were difregarded ; human flefh was expofed to fale in the open market. The more powerful feized their neighbors; fathers and mothers, their children ; hufbands, their wives, and offered them for fale. Multitudes of dead were found, with their mouths filled with ftraw, and the moft filthy fubftances. Five hundred thoufand perfons were fuppofed to perifh in Muf- covy, by famin and peftilence. At the fame time, the famin in Livonia, and the cold winter of 1602, deftroyed 30,000 lives. The dead bodies lay in the ftreets, for want of hands to bury them. Thuanus, lib. 135. Encyclopedia, art. Ruflia. At the fame time, raged a moft dreadful peftilence in Con- ftantinople, which alfo followed a famin. t In England, there was alfo a dearth, and in 1603 perifhed 36,000 in London, of the plague, which was faid to be imported from Oftend. Maitland's Hift. Lond. Mignot's Hift. Turkifh Empire, p. 256. Even in this cafe, the report of imported infection into Lon- don was believed, altho the nation had before their eyes, a de- monftration to the contrary ; for the fame malady broke out in every part of the kingdom, and had actually prevailed in Chefter, in the north-weft corner of England, the year preceding. It is idle to afcribe the plague to infection, communicated from perfon to perfon, or from clothes to perfons. The difeafe, in 1602 was in every part of Europe, and appeared nearly at the fame time, in the moft diftant parts. In this cafe, as in thofe before related, of 1580 and 1591, it had been preceded by catarrh, and a courfe of malignant fevers. The malignity of the difeafe in 1602 refembled that of 1348—perfons were fe? H with fpitting of blood, and died in three days. In Auguft 1603 in Paris died 2000 perfons weekly of the plague. This difeafe was attributed to the diet and filth accu- mulated, under a defective police. Wraxall, vol. 3. 438. Why the filth of Paris did not produce the plague in other feafons, writers have not informed us. *73 The period under confideration was remarkable for the unt* verfality of the action of fubterranean fire. The earthquakes of 1600 and 1601 and the burfting of a volcano in South-A- merica have.been mentioned. In 1603 there was an explofion of Etna. In 1604 a fecond eruption in Peru, and a comet. The plague abated, in fome places, the year following; but London was not free from it for a number of years, and from 1606 to 1609 inclufive the diftemper carried off from two to four thoufand citizens in each feafon. In 1607 commenced an unufual concurrence of great agitations in the elements, and fevere peftilence attended. In this year appeared a comet, and another in 1609. The winter of 1607-8 was the fevereft that had been known for an age ; boats were built on the Thames. And here for the firft time, I am able to introduce North-America, into this hiftory ; from which will be derived fome of the moft important evidence in regard to the univerfality of the caufes of peftilential epidemics. The feverity of the winter mentioned was equally great in America, as in Europe. George Popham, and a company of fettlers under the patent of king James, to the London mer- chants, attempted a fettlement at Sagadahoc in 1607 ; but Pop- ham, the Prefident, died during the winter, and the extreme cold was one of the difcouragements that contributed to break up the fettlement. Gorges Hift. New-England. Purchas, vol. 4. 1637. Hutchinfon's Hift. MalT. vol. 1. 2. In this fame year was an eruption of Etna.' The comet of this year produced a moft remarkable tempeft, with a fwell of the ocean, that did incredible damage in Eng- land. In the latter part of winter, the tempeft brought in a flood into the Severn, which overflowed the country, near Briftol, to the extent of ten miles, with a rapidity, that left no time for the people to fave their effects, and many lives were loft. The flood rofe above the houfes, where people had re- forted for fafety, and overwhelmed them. The lofs of cattle and goods was immenfe. In Somerfetfhire, the inundation laid wafte an extent of 20 miles by 1 o j overwhelming five towns. So fudden was the -74 irruption, that laborers were caught in the fields, and Were feen floating on the timbers of their houfes. In Norfolk, the inun- dation was not lefs deftructive. Thuanus, lib. 138.. In 1608 a very malignant dyfentery prevailed. In 1609 the approach of the fecond comet produced effects equally remarkable with the laft. The action of fubterranean fire was extenfiye. There was an eruption of Etna, and a vio- lent earthquake at Lima in Peru. The winter was fo fevere, as to convert the Thames into a common highway. In this year the plague was augmented in London ; and it raged in Alemar and Denmark. In the years 1607 and 8, it had been very mortal in Cork. The peftilential ftate of air, at this time* was experienced at fea. The people on board the fleet under Sir Thomas Gates and Sir George Somers, bound to Virginia, were feized with the calenture, a fpotted peftilent fever, which, on board of one of the fhips, was fo malignant as to be called the plague. Thir- ty-two dead bodies were thrown out of two fhips. Was this difeafe imported ? In the fame paffage, the fleet met with a tre- mendous ftorm of four days continuance, and Sir T. Gates was fhipwrecked on Bermuda. Purchas, vol. 4. p. 1733. In 1610 the catarrh was again epidemic. In fome parts of the continent prevailed the Hungarian fever like the plague, and fevere bilious complaints. A remarkable fiery bow in the heav- ens was obferved in Hungary; and Conftantinople was infefted with clouds of grafs-hoppers, of great fize, that devoured every green thing. The malignant fore throat was fatal in Spain, and authors relate that this was its firft appearance in that coun- try. In 1611 the plague carried off 200,000 of the inhabitants of Conftantinople. It appeared alfo in fome other places. The fummers of the three laft years were very hot and dry. In 1612 appeared a comet. A terrible tempeft made great havoc with fhipping—2000 dead bodies of failors were found on the coaft of England, and 1200 on that of Holland. Some towns were injured. In the following year, Provence in Franc* l75 ■was greatly injured by an inundation ; and fwarms of locufta fucceeded, which laid wafte the vegetable kingdom. The fummer of 1612 in England was exceffively dry, and a malignant fever feverely afflicted the nation. In 1613 the plague appeared in detached parts of France, and in Montpelier, a malignant difeafe fo fatal, as to want only the buboes, to prove it the true plague. It was marked with red and livid fpots, fwellings behind the ears and carbuncles. One third who were feized died. Riverius, lib. 17. The preceding fummers, the earth was covered with grafs- hoppers, and the air filled with clouds of flies. In this year alfo Conftantinople was ravaged with the plague ; and as cats were fuppofed to fpread the infeaion, the phyficians, who were moftly Jews, advifed the emperor Achmet I. and he accordingly ordered all the cats to be tranfported to a defert ifland near Scutari. Short, vol. 1. Mignot's Hift. Turkifh Empire. In 1614 the winter was fevere; there was an eruption of Etna, and an earthquake in the Azores. The heavens appeared, at one time in a flame, and afterwards very dark. This year was remarkable for the moft univerfal fmall-pox, and moft fatal ever known. It laid wafte Alexandria, Crete, Turkey, Calabria, Italy, Venice, Dalmatia, France, Germa- ny, Poland, Flanders and England. The mortality equalled that of the plague. In Perfia alfo it raged, with meafles. In 1615 the feafons were cold. In 1616 a very hot and dry fummer—quartan agues epidemic—not a family in Germany efcaped ; but not fatal. In 1617 the fummer was hot and dry. In 1618 appeared a remarkable comet in November, (Short mentions four) and a town in Rhetia was overwhelmed by an earthquake. Violent tempefts, inundations and hurricanes are recorded of the fame year, and in Bermuda, the year following, » ftorm tore up the ftrongeft trees by the roots. In 1619 Heckla difcharged her fiery contents. In 1618 broke out in Naples a malignant Angina which rav- aged the place for many years. The plague appeared at Bergen, >7« in Norway, in Denmark and in Grand Cairo. This was tha beginning of a very peftilential period, and here muft be intro- duced the terrible peftilence which wafted the American Indians, juft before our anceftors landed in Maffachufetts. As this is one of the moft remarkable facts in hiftory, and one that demon- ftrates the general caufes of plague to belong to other climates, befides thofe of Egypt and the Levant, I have taken great pains to afcertain the fpecies of difeafe, and the time of its appearance. Capt. Dermer, an Englifh adventurer, who had arrived in America, in a fifhing veffel, a year or two before, paffed the winter of 1618-19 in Monhiggan, an Indian town on the northern coaft. On the 19th of May 1619 he failed along the coaft, on his way to Virginia, and landed at feveral places, where he had ' been the year before ; and he found many Indian towns totally depopulated—in others a few natives remained alive, but " not free of ficknefs ;" " their difeafe, the plague, for we might perceive the fores of fome that had efcaped, who defcribed the fpots of fuch as ufually die." * Thefe are his words. He found fome villages, which, in his former vifit, were populous, all deferted—the Indians " all dead." Purchas, vol. 4. 1778. Richard Vines, and his companions, who had been fent by Ferdinando Gorges, to explore the country, wintered among the Indians, during the peftilence, and remained untouched, the difeafe attacking none of the Englifh. Belknap's Life of Gor- ges, American Biography, vol. 1. p. 355, but the year is not fpecified. Gookin, in his account of the Indians, Hiftorical Collections, • p. 8, places this peftilence in 1612 and 13, about feven or eight years before the Englifh arrived at Plymouth. But this cannot be accurate, unlefs the difeafe began to rage for a number of years previous to 1618. Capt. Dermer's letter in Purchas is decifive of the time of the principal ficknefs, and fortunately we have another authority which is indifputable. A fermon was preached by Elder Cufhrmn at Plymouth, in 1620, juft after the colony arrived, and fent to London to be publifhed. In the Epiftle Dedicatory which is dated December, 21, 1621, the author has thefe words. " They [the Indians] J77 were very much wafted of late, by a great mortality, that fell amongft them, three years fince, which, with their own civil diffentions and bloody wars, hath fo wafted them, as I think the twentieth perfon is fcarce left alive." Hazard's Collection, vol. i. p. 148. This correfponds alfo with the accounts in Prince's Chronol- ogy from original manufcripts. This fixes the time in 1618> precifely agreeable to Capt. Dermer's account. This was the year. of the principal mortality ; but like other peftilential pe- riods, this continued for a number of years ; for fome of the Plymouth fettlers Went to Maffachufetts, (now Bofton) in 1622, to purchafe corn of the natives; and " found among the In* dians, a great ficknefs, not unlike the plague, if not the fame." It raged in winter, and affected the Indians only. See Purchas 4. 1858. Prince's Chron. 124. The time then is fixed. The difeafe commenced, or raged with its principal violence in 1618 and through the winter. This was the year of the remarkable comet, when the plague was raging in many parts of the world. So fatal was the peftilence in America, that the warriors from Narraganfett to Penobfcot, the diftance to which the difeafe feems to have been limited) were reduced from 9000 to a few hundreds.* When our an- ceftors arrived in 1620, they found the bones of thofe who per- ifhed, in many places, unburied. Magnalia, book 1. p. 7. The kind of difeafe is another important queftion. Dermer feems to think it a fpecies of plague, and he faw fome of the fores of thofe who had furvived. Hutchinfbn, vol. 1. p. 34, 35, fays fome have fuppofed it to have been the fmall-pox, but the Indians, who were perfeftly acquainted with this difeafe, after the Englifh arrived, always gave a very different account of it, and defcribed it as a peftilential putrid fever. Fortunately General Gookin, in the paffage above cited, has left us a faa, which leaves no doubt as to the nature of the mal- ady. His words are—" What the difeafe was, which fo gen- * Hutchirifon fays, 30,000 of the Maffachufetts tribe alone were fuppofed to be reduced to 300. Y 178 erally and mortally fwept them away, I cannot learn. Doubt- lefs it was fome peftilential difeafe. I have difcourfed with fome old Indians, that were then youths, who fay, that the bodies all over were exceeding yellow (defcribing it by a yellow garment they fhowed me) both before they died and afterwards." This account may be relied on for its authenticity and it de- cides the queftion, that the peftilence was the true American •plague, called yellow fever. If any confirmation of this evi- dence were neceffary, we have it in Prince's Chronology, where it is recorded that this fever produced hemorrhagy from the nofe. At the time Gookin wrote, about forty or fifty years after the fettlement of New-England, the infectious fevers of autumn were called " peftilent," and they were frequent in the country, but had not then acquired the appellation of yellow. Winthrop's journal, p. 51. This fever has been frequent among the Indians fince the Eng- lifh fettled the country. Some inftances will be hereafter related. The evidence then of the origin of the yellow fever in this country, between the 41ft and 44th degrees of latitude, is com- plete, leaving no room for doubt or controverfy. No intercourfe exifted, in 1618, between this continent and the Weft-Indies; nor did a fingle veffel pafs between New-England and the iflands, till twenty years after that peftilence. Not one of the iflands was then fettled, except by the Spaniards, with whom our an- ceftors had no commerce. Not an European was among the Indians, except a French feaman, who had efcaped from a wreck a year or two before, and Mr. Vine's men, who arrived di- rectly from England. Thefe men efcaped the difeafe ; none be- ing attacked but the Indians ; another evidence of the origin of the malady in the country. In Gorges' defcription of New-England, there is the follow- ing account of this peftilence. " The fummer after the blazing ftar, which moved from the eaft to the weft, even a little before the Englifh removed from Holland to Plymouth, in New-Eng- land, there befel a great mortality among the Indians, the great- eft that had ever happened in the memory of man, or been ta- ken notice of by tradition, laying wafte the eaft." tyg The author further remarks that this ftar was much noted ift Europe. In America it was feen in the fouth-weft, for " thirty: fleeps," as the Indians exprefs themfelves. The defcription of the comet here given anfwers to that of Riverius, who repre- fents it as very fplendid, larger than Venus, moving from the eaft to the weft, and vifible from Nov. 27, 1618, till the clofe of December. This was the time the peftilence was raging among the Indians. Gorges indeed fays, it was the fummer after the blazing ftar. It is true, that the difeafe continued not only into 1619, but occurred in autumn for fome years fubfe- quent. We hear of it among the Maffachufetts Indians in 1622. From this it appears that this was a long and fevere period of peftilence, between 1617 and 1623, or a later year; like the prefent period in the United Statec. It muft be remarked that in 1618, the fame year when the In- dians in America were falling a prey to this malady, the angina ma- ligna broke out in the kingdom of Naples, and fpread mortality over the country, as authors affirm, for eighteen years. This how- ever is not underftood, as affirming the difeafe to have been con- ftantly epidemic ; but as prevailing at certain times and feafons. The fame deftruaive principle operated in Virginia. Capt. Dermer relates that when he arrived in the Chefapeek on the 8th of September, " The firft news ftruck cold to our hearts, the ficknefs over the land."* Three hundred of the fettlers died in 1619. It appears from Purchas that the emigrants to Virginia in 1619, 20 and 21, amqwited to 3570, in 42 fail of fhips.f There were 600 fouls in that colony before thefe arrived, mak- ing the whole number 4170. Of thefe, 349 perifhed in the Indian maffacre of 1622, which would leave 3821 furvivors. But in 1624 no more than 1800 were living. Scanty means of fubfiftence might have contributed to this mortality ; but moft of it was in confequence of fevers, that were probably the ef- * Capt. Dermer was probably the firft Englishman that ever palled through the rapids between Long-Iiland and the mainland, now called Hell-Gate. He defcribes this paflage as a cataract, and mentions the difference in times of high water, from the eaft and weft. f Mr. Jefferfon allows only 1516 perfons to have arrived in that period. I$0 fetts of the climate, and a very unfavorable, ftate of the atrrrof- phere. In 1620 a comet was followed by a cold winter. In. England the year was diftinguifhed by a violent tempeft, a preternatural tide, and a very wet fummer- The Hungarian fever, fo called, fpread along the Rhine, and in the next year became infeaious. London became fickly. The year 1621 was remarkable for an epidemic malignant fmall-pox. In 1622 a comet is noted, and an earthquake in Italy. In New-England the fpring was exceffively dry, from the tbiid week in May to the middle of July. In 1623 the epidemic fevers in Europe became more fatal, as the period of peftilence approached. This is obvious from the London burials, which fhow a confiderable increment. Rive- rius, who has written on the epidemic fevers of this period in the fouth of France, obferves that the mortality was great, until he began to bleed and purge, when it abated. He refers to the city of Montpelier, where almoft half died who were feized. The difeafe was a fpecies of peftilence. This author concurs with the ancients in afcribing peftilence to comets. Speaking of the fingular ftar of 1618, he fays, " Hunc vero Cometam, morborum malignorum et peftilentium, necnon etiam bellorum, quibus univerfa pene haaenus Europa deyaftata eft, praefagium ac prenuntium fuiffe, credere non alie- num eft." De febre peft. 533. fol. The author falls JBto the error, which has brought into con- tempt the opinions of the ancient fables, in regard to the influt ence of the ftars on man, and the ftate of the elements. He jffcribes moral as well as phyfical effeas to that influence. Ad- mitting the diftant orbs to have fome effea on the air or fire of our fyftem, and through that medium to augment or diminifh the ftimulus which aas on the human body and of courfe on the paffions, by the exciting powers ; yet any moral effeas derived from this fource, muft be fo inconfiderable, or fo blended with the effeas of other caufes, as intereft, ambition, love, revenge and the like, that the degree of influence could not be afcer- tained, nor the effects of one caufe diftinguifhed from thofe of the 'l*I other. I rejeft therefore all moral effeas afcribed to comets 5 but the phyfical effeas are, beyond queftion, great and extenfive. The difeafes of this period continued to multiply and grow more malignant in 1624, when the epidemic affumed the form of the fpotted fever. In 1625 this fever turned to the plague, and in 1626 changed back to the fpotted fever, fays Lotichius, Cited by Short. This is not an unufual faa. The plague in 1625 fwept away 35,000 of the citizens of London. It raged at the fame time in Italy, Denmark and Leyden, and how much more extenfively, I am not informed. In this year another comet was feen ; feveral cities in Spain were overwhelmed by inundations ; the winter was fevere ; the fummer, hot and moift weather ; and there was an eruption of a volcano in Iceland. It is remarkable alfo that, in this year, a volcano burft forth in Palma, one of the Canaries, with a vi- olent earthquake. The fummer of 1626 was very hot, and the plague continued its ravages in many parts of Europe, as in Wittemburg and the vicinity; and in Lyons, which loft 60,000 of its inhabitants. This was the prelude to more general calamity in France ; for in the following years the whole country felt the diftreffing ef- feas of the malady. In 1627 and 8 the fame difeafe prevailed in various other countries, efpecially in Augfburg after a famin. In 1629 the peftilence raged in Amfterdam. In 1630 Cambridge in Eng- land was vifited. It was a very fickly fummer in London, fo that the citizens were alarmed and many retired to the country; but finding the country very fickly, they returned. In 1629 Pola, a town in the Venetian territories, loft 700a inhabitants by an earthquake. Of the peftilence in this period, there was hardly a fufpen- fion. Particular countries enjoyed fhort intervals of health; but Europe and America were feverely annoyed by peftilential difeafes between 1632 and 1637. In 1630 happened great explofions of fubterranean fire. A- pulia ldft 17,000 people by an earthquake; and Lima, in South- i?2 America, was laid in "ruins by the like cataftrophe. At this time the plague prevailed in Vienna. In 1631 happened a memorable earthquake in Naples, with a tremendous eruption of Vefuvius, which continued or was re- peated in 1632. In this eruption, Baglivus affures us, Vefu- vius loft 240 feet of its altitude. Cotemporary with thefe difcharges of fire and lava, was an tryfipelous fever in Europe with inflammation in the jaws, and an increafe of mortality, antecedent to a general plague. See the bills of mortality for London, Augfburg and Drefden, where the progrefs of the malignity in the epidemics, is diftina- ly marked, by an augmentation t>f the bills, till the plague in 1636. In 1633 appeared a comet, which was followed by a fevere winter. The fame winter in America was mild, fays Winthrop, p. 61. Southerly winds prevailed till the clofe of winter, when there were great fnows. It is very common that fevere cold is progreflive, happening in Europe one year before it does in A- merica, as will hereafter appear. In 1633 the year of the comet, commenced an eruption of Etna, which continued for four or five years, through this whole peftilential period. London was fhaken by an earthquake, and at Halifax in Yorkfhire raged a very malignant fever. In this year alfo a " peftilent fever," invaded the little colo- ny at Plymouth in Maffaehufetts, and carried off twenty of their number. This was a great mortality for that fmall fettle- ment. It muft have been occafioned by a fever of domeftic ori- gin, a6 the colony had, at that time, no intercourfe with for- eign countries, except with England. No fufpicion has ever been entertained that the difeafe was of foreign origin. At the fame time, the Indians were invaded by the fmall-pox which fwept them away in multitudes. It fpread from Narra- ganfett to Pifcataqua, and weftward to Conneaicut river. The fummer of this year was remarkable for innumerable large flies, of the fize of bees, which made the woods refound with a humming noife. Hubbard's M. S. p. 131. Winthrop's Journal, 51—56—59—61. We have then a remarkable evidence of the extent of a pef- l83 tilential principle in the elements. The fame fpecies of difcafel appeared, at the fame time, in Augfburg, Drefden, London, and in America. Probably the fame fpecies prevailed over moft; of Europe ; for we hear of them in every part of Holland in the following year. The difeafes predominant, previous to the plague, are of the eruptive kind : Such was the cafe in the pref- ent inftance. In America, the epidemic among the Indians took the form of the fmall-pox ; and altho it is the current opin- ion that the fmall-pox is communicated only by contagion, yet my inveftigations have fatisfied me that this is a great error- The fmall-pox is one of the family of eruptive difeafes, which belong to almoft every peftilential period. Before its origin and progrefs diad been affeaed by the art of innoculation, it ufed to be epidemic, in large cities, under that inflammatory conditioa of the atmofphere, which origiaated mealies, influenza, anginas and plague, and rarely or never at any other time. This difeafe therefore, tho communicable at any time by infeaion, is gene- rated in particular habits without any infixing caufe ab extra ; and is the offspring of that ftate of the atmofphere which gen» erates other eruptive epidemics. In 1634 the plague fhowed itfelf at Ratifbon. The fummer in America was hotter than ufaal, and the following winter was very cold. In 1635 the plague appeared in Leyden and 20,000 inhabit- ants periflied. This year was diftinguifhed for an eruption of Vefuvius, violent earthquakes, an inundation in Holftein which deftroyed 6co people and 50,000 head of cattle, and a terrible tempeft in America on the 15th of Auguft O. S. which brot in a remarkable fwell of the' ocean. It will appear hereafter that moft of the violent ftorms and hurricanes, which fweep the earth, happen during or near the time of the difcharges of great} quantities of fire from volcanoes. In this year, Etna and Ve- fuvius were both in a ftate of eruption. The plague appeared alfo in Mentz and other parts of Germany. In 1636 there was an eruption of Heckla. The peftilence was general in proportion to this univerfal agitation of the central 184 fires. In London it prevailed in 1636 after a regular increafe of previous malignity in difeafes. Of the progrefs of the peftilence in Holland, and efpecially in Nimeguen, we have an accurate account in the treatife of the able Diemerbroeck, which is by far the moft learned and philo- sophic work on the plague, that I have feen. Not that I believe his opinion of the caufe of the plague ; but his view of the fub- jea is otherwife correa and worthy of univerfal attention. In 1635 when the plague appeared in Leyden, the malignant difeafes, its precurfors, appeared in various parts of Holland. In Nimeguen, thefe precurfors were meafles, fmall-pox, dyfen- teries of the worft type, but efpecially the fpotted fever. The malignity of this fever increafed, until it changed Into the real plague—" donee in apertiflimam peftem tranfiret," fays Diemer- broeck. The plague appeared, in a few cafes, in November 1635, but made little progrefs, during the winter. In January appearan- ces were more alarming ; in March the malady fpread rapidly and continued to increafe till autumn. Scarcely a houfe efcaped; more than half who were feized, died ; and medical aid was baffled. The difeafe declined in the following winter, and was extinguifhed by a fevere froft in February 1637. The fummers of 1636 and 7 were warm, the winds conftantly from the fouth and weft, *' cum magnis aeris fqualoribus," fays Diemerbroeck. In 1635 a dyfentery prevailed in moft parts of Germany. In 1636 the eruption from Etna was augmented, and Rome was feverely aflliaed with the plague. In 1637 the fame diftemper raged in fome parts of Holland, in Denmark, Conftantinople and Natolia ; after which year the difeafe declined or difappeared. This period of difeafe was alfo experienced in Virginia, where, fays Winthrop, died 1800 people in the year 1635. The fummer of 1638 was very hot and dry in England, as it was in America, after a very fevere winter, and cold fpring. In this year was a moft tremendous earthquake in Calabria, memorable for the deftruaion of whole towns and the lofs of 30,000 lives. 185 - On the iirft of June, between 3 and 4 o'clock in the after* poon, in a clear warm day, with a wefterly wind, happened a great earthquake in America, which extended from the Pifcat- aqua to the Conneaicut, and perhaps over the whole northern region. The year was alfo diftinguifhed for tempeftuous weath- er ; not for ordinary ftorms which occur many times every year, but violent hurricanes of vaft extent. On the third of Auguft a tempeft raifed the tide, on the Narraganfett fhore, fourteen feet above common fpring tides. Autumn was very rainy and confiderable fnow fell in Oaober, which our anceftors afcri- bed to the earthquake. On the 25th of September, another mighty tempeft occurred and the higheft fwell of the fea that had then been obferved in America. If I miftake not, the ftate of the atmofphere, during earthquakes and eruptions of volca- noes, is peculiarly difpofed, not only to produce high wind?} but to generate fnow and hail. This year was very fickly in America. In December a gen- eral faft was obferved, one reafon for which was the prevalence of the " fmall-pox and fevers." Winthrop, p. 16 c. The fpring of 1639 'n America was very dry, there was no rain from April 26th, to June 4th, O. S. and from the fouth* ward came fwarms of fmall flies, which covered the fea, but *hey d»d not invade the land. Winthrop, p. i8r—184. The plague continued to infeft London, without interruption, from 1636 to 1648 ; fee the bills of mortality ; but it was not epidemic, nor very fatal. In 1640 a hard winter, and epidemic pleurifies were fatal iq Europe. The following year, a malignant fever was epidemic, in England, and other countries. In September nth appeared, in the evening, a remarkable light in the heavens, about 30 or 40 feet in length; it moved rapidly and was vifible about a minute. It was feen in Bofton, jn Plymouth and in New-Haven, and to the fpeaators every i86 where, appeared to be in the fame part of the heavens—of courfe muft have been of a great altitude. Winthrop, p. 232. I notice this faa as it confirms the teftimony of ancient wri- ters, who, in defcribing the feafons and phenomena of pefti- lential periods, frequently mention fimilar appearances. This feems to have been of the figure of a beam, called by the Latin writers, trabs, but it differed from thofe meteors difcribed by ancient writers, in the rapidity of its motion. In November following a feries of tempefts took place, and die higheft tide ever known at Bofton. This furnmer of 1641 was remarkably wet and cold, fo that a great part of the corn did not come to maturity. Thofe who fed on it, the year following, were exceedingly troubled with worms, and fome perfons found a remedy in leaving bread and living on fifh. Winthrop, p. 234. The following winter was the moft fevere that had been known for 40 years. The bay at Bofton was frozen fo that teams and loads paffed to the town from the neighboring iflands. The fnow was deep, and Chefapeek bay was nearly frozen. At Bofton, the ice extended to fea, as far as the eye could reach. The following fpring 1642 was early, but wet. Winthrop, p. 340, 243. The oldeft Indians declared they coujd fcarcely recollea fuch a winter. This fevere winter was followed by a very fickly fummer on the Delaware river. Such was the mortality among the fettlers from New-Haven, who had not long been in that country, that it broke up their fettlement. The Swedes fettled there fuffered much by the fame difeafe. Ibm. 354. The very wet weather of the laft year produced a dearth of corn in Bofton, in the fpring of 1643, and myriads of pigeons appeared alfo and did no fmall injury, the fame feafon. It is an old obfervation, in America, that pigeons are uncommonly nu- merous in the fpring of fickly years. The Maffachufetts colony fuffered alfo from the number of mice which devoured their grain, and the bark of the fruit-trees. 187 . Several fingular meteors were feen this year in the neighbor* hood of Bofton.* One fact in the foregoing account deferves notice; the ex- treme winter in America was in 1641-2, one year later than ia Europe. Several inftances have occurred in other periods, Which feem to indicate a kind of progreffivenefs in great cold from eaft to weft. It often happens however that the winter is fevere at the fame time, in both hemifpheres, as in 1607-8— 1683-4—x 762-3—1779-80. In England, in 1643 a malignant fever was epidemic and few efcaped. In autumn, it put on peftilential fymptoms and pe- techias The fame year, an eruption of Vefuvius and of Etna. In 1644 a malignant fever was epidemic in Denmark. The fummer of 1645 being exceffively hot, there prevailed a contagious dyfentery, which was fatal in England. For the great mortality in England, through a feries of years at this time, fee the London bills. In this year a great ficknefs prevailed among the Indians oa Martha's Vineyard—few efcaped. Neal's Hift. New-England, vol. 1. 264. In 1646 inundations laid a part of Holland, Friefland and Zealand under wj.ter fo fuddenly, as to deftroy more than one hundred thoufand lives and three hundred villages. Gorges re- ^ fates that two mock funs, with other fingular celeftial phenomena, were feen this year in America. P. 41. In 1647 May 13th, a moft tremendous earthquake in Chili, South-America, funk whole mountains into the earth and nearly ruined the large city of Santiago. Ulloa, book 8. ch. 7. This year appeared a comet. The plague in London alfi» was more fevere, and appeared after this year to fubfide. In 1646 and 7 the Ukrain was ravaged by locufts. * Here ends Winthrop's Journal—a circumftance to be regretted. Hubbard's Manufcript will in part fupply materials for this work, for fome years fubfequent. But for the laft 30 years of the laft centory, I can obtain very little information of the ftate of the feafons as4 health in America. iS8 A. Di t647- This year appeared an epidemic catarrh i;'s America, and the firft of which we have any account. It is not named either influenza or catanh, but is clearly the fame difeafe. It is thus defcribed in Hubbard's Manufcript, p. 276. " In 4647 an epidemic ficknefs paffed through the whole country, affeaing the colonifts and the natives, Englifh, French and Dutch. It began with a cold and in many accompanied with a light fever. Such as bled or ufed cooling drinks died—fuch as made ufe of cordials and more ftrengthening things, recovered for the moft part. It extended through the plantations in Amer- ica, and in the Weft-Indies. There died in Barbadoes and St. Kitts, 5 or 6000 each. Whether it was a plague, 01 peftilential fever, in the iflands, accompanied by great drouth, which cut fhort potatoes and fruits." This epidemic was in the fame year with the earthquake in Chili, but the date of the difeafe is not recorded. In Conneaicut prevailed a malignant fever, occafioned by the exdeflive heat of the fummer. f The year 1648 appears to have been lefs fickly, in London ; but in the fouth of Europe, malignant difeafes were the harbin- gers of the plague, which in 1649 carried off 200,000 people in the fcuthern provinces of Spain. In Ireland and Shropfhii e the plague prevailed in the fame year, and a fatal fever in France. The fmall-pox was epidemic in Boftop. Townfend's Travels, vol. 2. 219. Short, vol. 1. Douglas' Summary, vol. 2. 395. In 1650 was an eruption of Etna, and an earthquake in the iiorth and weft of England. In this and the following year the plague continued in Ireland. In 1650 the influenza fpread over Europe. In 1651 many defolating floods happened in Holland and France—in Italy, a quinfy or fore throat proved very fatal to children. Thefe dif- eafes were fucceded by malignant fevers, and plague in moft parts of Europe, except in England. The fummer of 1651 was hot. In 1652 appeared a comet. A dangerous fynochus prevailed in Fiance and a tertian fever in Denmark. t Of this fever died the Rev. Thomas Hooker, and many others in Hartford, Sec Neal's Hift. N. E. vol. 1. 289. Magnalia, b. 3. 67. 189 In 1653 a flight earthquake occurred in New-England, in OcY. The years 1652 and 3 were remarkably dry in England, and in 1654 public thanks were ordered for a fupply of rain. Mercurius Politicus. In 1654 the plague made its appearance in Denmark. Some fevere epidemic had prevailed in New-England ; for in the fpring of 1654 a general faft was appointed by the government of Con- neaicut, one reafon affigned for which was, " the mortality which had been among the peopla of Maffachufetts." What the difeafe was, I am not informed. Trum. Hift, Con. 225. In 16^5 occurred the fecond epidemic catarrh, recorded in the Annals of America. The following is the account of it in Hubbard's Manufcript, p. 285. " In 1655 there was another faint cough that paffed through the whole country of New-England, occafioned by fome ftrange diftemper or infeaion of the air. It was fo epidemical, that few perfons efcaped. It began about the end of June. Few were able to vifit their friends or perform the laft teftimony of refpea to any of their relations at a diftance. Of this died Mr. Nathaniel Rogers, miniftcr of Ipfwich." See alfo Magnalia, b. 3. 108. It will be obferved that this epidemic commenced in the heat of fummer, and that its invafion was fudden and univerfal. In November 1655 occurred an earthquake in South-America. Of the feafons in America I have no account; but in Europe the winter of 1654-5 was extremely fevere. The rivers and harbors in Holland were all made faft with ice ; a feries of fnow ftorms took place in April, and as late as the 19th there was a fevere froft at Bruffels. See Mercurius Politicus, a London paper for 1655. In March 1655 was an eruption of Vefuvius; it was very fickly in the north of England ; and there were great tempefts of Wind and hail in 1654 and 5. In 1654 the plague appeared at Chefter in England ; but did not become epidemic ; owing, it was fuppofed, to the precaution of confining the difeafed to their houfes.* At the fame time * This may poflibly hive been the cafe ; but it is probable the opin- ion is not weli founded. See this point confidered in the 16th fectioa. igo $e difeafe was raging in Turkey, in Prefburg, Hungary and in the city of Mofcow, it is alledged, periflied 200,000 inhabitants. We have here precife and authentic evidence, that the plague appeared in Chefter, in the north-weft of England, in Denmark, in Ruflia, Hungary and Turkey, in the fame feafon. To prove this to be the effea of a general principle, we have numberfefs authorities, in the Gazettes of that and the next year, that ma- lignant difeafes prevailed over Europe. See the paper above cited. Thus when a few cafes of plague occurred in Chefter, fatal dif- eafes prevailed over the north of England. And it is remark- able in this inftance, that the epidemic plague appeared in the north of Europe before it did in Italy—an exception to die gen- eral courfe of that difeafe. In 1655 the plague was more general in Europe. It prevailed injSardinia, Malta, Leyden, Amfterdam, and in Riga, a Ruf- fian port at the mouth of the Divina. There died in Riga 9000 —Amfterdam 13,200—Leyden 13,000. In 1656 the fame difeafe invaded Naples, Rome, Genoa, Candia, Benevento, and moft parts of the Neapolitan territories. In the city of Naples, perifhed three fourths of the inhabitants, and in Benevento, a greater proportion. The numbers of deaths were eftimated as follows— In the city of Naples died 240,000—furvived 50,000. In the Neapolitan territories 400,000. In Benevento died 9000—furvived 500. In Rome about 10,000. In Genoa in 1656, 10,000, and in 1657, 70,000, and 14,000 only furvived. In Riga 9000. In Thorn 8200. I have not materials for a complete view of the difeafes of this peftilential period. But it is to be obferved, that influenza prevailed over Europe in 1650, and difeafes of the throat in It- aly in 1651—difeafes which feem to precede peftilential fevers on moft occafions. » The fummer of 1656 was hot, and an earthquake in the fouth of Italy accompanied the dreadful mortality. See Univ. Hift. vol. 2%. 318. Mercurius Politicus, 1656. Encyclopedia, art. Plague. 19-i The influenza in America was alfo fucceeded by fatal epidemic difeafes, altho I have no means of determining what they were. The account recorded is that there " was a great ficknefs and mortality, throughout New-England in 1658. The feafon was intemperate and the crops light." Trumbull, p. 244. This year was alfo diftinguifhed for what is called in our annals, the " Great Earthquake." This is an inftance of a violent con- cuflion of the earth, in the fame year with violent rains ; but unfortunately I can find no account which phenomenon preceded the other. The fummer was fb rainy, that the chriftianized Indians obferved days of fafting, on that account, apprehending that their crops would fail and the world be drowned. Neal, vol. 1. 259. The introduaion of the plague into Naples was afcribed to a tranfport of foldiers from Sardinia. How the difeafe came to be in Sardinia, we are not informed. But this report, like nine tenths of all the ftories about infeaion, is demonftrably a mif- take. The account given in the hiftory of the difeafe, is, that it was at firft called by phyficians a " malignant fever." One of the faculty, a man probably of more obfervation and firm- aefs than the others, affirmed the diftemper to be peftilential, and for his audacity, was imprifoned by the Viceroy, who ap- prehended the report might injure the bufinefs and reputation of the city. We have then another inftance of the uncertainty in the minds of medical gentlemen, about the nature of the difeafe, when it firft appeared, becaufe it was-not charaaerized by the diftinaive marks of the plague, the glandular tumors. This circumftance demonftrates that the difeafe was not imported, but an epidemic ; appearing firft, as all great plagues firft appear, in the form of catarrh, inflammatory fevers, affeaions of the throat, and typhus fevers. There cannot be a more clear and demonftrable truth, than that a difeafe of fpecific contagion, muft communicate a difeafe of the fame fpecific charaacr. If the plague has this fpecies of contagion, it cannot communicate another difeafe, a malignant fever, for inftance, which has a different charaaer or type, and 192 16 deftitute of the diftinaive marks of the plague. A fingle iii., ftance might occur, in which the difeafe might not bear the charaaer of its original; but it is abfurd to fuppofe, that a plague with glandular tumors, can communicate and render epi- demic a fever without glandular tumors. Yet all fevere plagues firft appear in the form of fuch fever, Or other difeafes without tumors. I challenge the followers of Mead to produce an exception. Hence the uncertainty that per- plexes the phyfician and the magiftrate at the commencement of the plague—an uncertainty that has originated in the errors re- fpeaing the fpecific nature of the difeafe and its propagation hy infeaion—errors as fatal to great cities, as to truth and philofo- phy. Had the real origin of this difeafe been known, the certainty of the exiftence of it in Naples, Venice, Rome, Vienna, Am- fterdam and London, would have induced the citizens to aban- don the places, before the diftemper had made much progrefs, aad multitudes of lives would have been faved—an expedient praaifed in America, with the moft falutary effeas. In Genoa, the difeafe manifefted a more diftina progreffion ; 10,000 died the firft year, and about 70,000 the fecond. When this diftemper appeared in Malta, Candia and Sardinia, every poflible precaution was taken to prevent its introduaion in- to Genoa, by flopping intercourfe with thofe places ; but in vain. When the report of a malignant infeaious fever in Naples prevailed in May 1656, an alarm was excited in Rome; a com- mittee of health watched over the fafety of that city ; four of the gates were fhut and barred ; the others were guarded with' vigilance to prevent any perfon from entering who could be fuf- peaed of infeaon ; but all effortswere ufelefs. The real trutfc ' was*the difeafe was an epidemic, no more under the control of health laws, than the influenza and fore throat which had pre- ceded it. The fummer of 1657 in England was very hot, and fucceed- ed by a long fevere winter and deep fnow. In April 1658 commenced in Europe an epidemic catarrh, which v/as fo fudden in its attack as to feize a whole village io a 121 night. It was fevere and fatal to old people—its courfe was fi»« ifhed in about fix weeks. The fummer was hot and fevers with vertigo and delirium, were epidemic. See Short, vol. i. and Morton's Treatife. It will be remarked that the year 1647 when the influenza invaded America, was a fickly year in Europe. In 1655 when the plague was epidemic in Europe, the influenza again prevailed in America. In 1658 when the influenza invaded Europe, great ficknefs and mortality occurred in America, Thefe alter- nations of epidemic difeafes will be obferved in the fubfequent ftages of this hiftory. In 1659 prevailed the Cynanche Trachealis in America—the £rft inftance mentioned in our annals. Magnalia, b. 4. 156.—^ This difeafe was alfo fucceeded by malignant difeafes, for the Legiflature of Conneaicut in Oaober 1662 appointed a day of thankfgiving, two reafons afligned for which were, the " abate- ment of the ficknefs in the country, and afupply of rain in time of drouth." This was the commencement of a very fickly period in Europe* In 1660 occurred ah eruption of Vefuvius, and of a volcano in Iceland. The year was very tempeftuous, and earthquakes fhook England, France and America. In 1661 appeared a comet. In 1662 another confiderable earthquake happened in New- England ; and in this year was the drouth above mentioned.—* In 1663 Canada was convulfed for five months by a feries of fucceffive fhocks—fmall rivers and fprings were dried up—the waters of others were tinaured with the tafte of fulphur—an immenfe ridge of mountains fubfided to a plain. Such were the .phenomena in America which marked this peftilential period. Mem. Royal Society, vol. 6. 86. Neal's Hift. N. England. Mtm. Amer. Acad. vol. 1. 263. In 1663 a malignant difeafe feized the inhabitants of the Ve« netian territories and 60,000 perifhed. The country, at the fame time, was overrun by innumerable fmall worms. In the fame year, a memorable mortality occurred in England, among the cattle and fheep, by means of a difeafe in which the A a 194 liver was eaten by fmall worms, and in fome cafes, the lungs. JThefe phenomena were the precurfors of the plague in many pai*s of Europe. In England* all difeafes affumed new violence, as early as in 1661, preparatory to the great plague. See Sy- denham. In Holland, the plague appeared at Heufden, in 1663. The winter of 1663-4 was mild. In the following fummer, Pruffia was afliiaed by a malignant purple fever, attended with tumors or inflammatien in the throat, very fatal to the young, Bonnetus. Med. Septen. p. 206. A fpecies of fcarlatina. In 1664 appeared a comet ; another in 1665, and a third in 1666. In 1664 began an eruption of Etna, which lafted, with various degrees of violence, till the year 1669, when it ended with a moft dreadful explofion. This period corresponds with the epidemics defcribed by Sydenham. In 1664 the fummer in England was wet, and cattle died of difeafes. In New-England commenced the mildew of wheat, which has rendered it impoflible to cultivate that grain, on the Atlantic coaft of the three Eaftern States. The winter of 1664-5, was terribly fevere in England ; the Thames was a bridge of ice, and in January happened earthquakes, in Coven- try and Buckinghamfhire. During this winter inflammatory fevers and quinfies, fays Sydenham, were more frequent in Lon- don, than were before known. Thefe gave way in May to a malignant fever, which could hardly be diftinguifhed from the plague, which, in June, became the controling epidemic. Such were the phenomena of the peftilential period under con- fideration ; and at this time, the plague appeared in Holland^ and in England. Englifh authors all agree that the difeafe was imported into England from Holland in fome bales of cotton ! O fatal bales of cotton ! fays Short. This tale has been record- ed and repeated by every writer on the fubjea, without a fingle document in evidence to prove that any cotton was imported, or that the firft perfons feized had ever feen fuch cotton. The whole tale refts on affertion. That the feeds of the diftemper were not imported is evident from die acknowledged fiufts relative to its origin ; and is demonftrated by the hiftory of the prece.i ding difeafes'found in the works of Sydenham. m The origin of the peftilence, which arrived to its crifis in J 665, is to be traced back to the year 1661, when malignant dif* ea&s began to appear in different and diftant parts of the world. In London, the intermitting tertian fever, fays Sydenham, be-> came epidemic, and differed from the fame difeafe in other years, by new and unufual fymptoms, which in fhort, amounted to this, that they were " all more violent." In winter, the difeafe yield- ed, as ufual, to cold, but continued fevers prevailed every win- ter. Thefe fevers, with fome variations, continued until the fpring of 1665, and the bills fhow how much they augmented the mortality in London. This increafed malignity in ufual dif- eafes, with an increafe of the number and mortality of epidemics, is the conftant precurfor of the plague or other peftilential fevers. Notwithftanding the clear evidence of thefe facts, authors have conjured up a tale of importation which would difgrace a fchool- boy by its inconfiftency.* The account ftates, " That a violent plague had raged in Holland in 1663, on which account, the importation of merchandize from that country was prohibited by the Britifh Legiflature in 1664. Notwithftanding this prohibi- tion, it feems the plague hadaaually been imported ; for in the clofe of 1664, two or three perfons died fuddenly in Weftminfter, with marls of the plague on their bodies.—Some of their neighbors, terrified at the thoughts of their danger, removed into the city ; but too late ; for they foon died of the plague, and communi- cated the infeaion to others. It was confined however through a hard, frofty winter, till the middle of February, when it again appeared in the Parifh of St. Giles, to which it had been ori- ginally brought; and after another long reft, till April, fhowed its malignant force afrefh, as foon as the warmth of fpring gave it opportunity. At firfl, it took off one here and there, without any certain proof of their having tnfe3ed each other. Encyclopedia, art. London, at. In the fubftance of the foregoing ftatement, all authors are agreed, and I want no other proof that the report of the impor- tation of the difeafe is all a vulgar, childifh tale, the propagation * If this language fhould be thought too fevere, I can fincerely fay, that in my opinion, no language can be too fevere for the careleflhefs which-has originated a fyftem of error on this important fubject. 196 cf which is a difgraceto philofophy and to the faculty of that age. In the firft place we have no authentic evidence in any author, that any bales of cotton were brought from Holland to London, at that time. The whole affertion refts on vulgar report, and is wholly unfupported by proof—had the report been well founded, the faa might have been afcertained, and in an affair of fuch magnitude, probably would have been. The importation of goods from Holland was prohibited by aa of parliament. In the fecond place, the difeafe firft appeared in Weftminfter, not in the commercial city of London, but in a place where bales of cotton would be the leaft likely to be depofited and opened ; Weftminfter being the refidence of the nobility and gen- try, rather than a place of commerce. In the third place, no proof is ftated that the peifons firft feized had any conneaion with bales of cotton. In the fourth place, the death of two or three perfons, with the plague-mark's on their bodies, in December 1664, is-no evidence of any imported infeaion at that time ; for the bills of mortality fhow, and the reader is defired to turn to them, to be fatisfied, that afmaller number died that year of the plague, than had died of it in any of the fix preceding years. In the year 1659 died of that difeafe 36—in 1661 died 20, and every year more or lefs. In 1664 died but 6 of the plague, and yet this number, fmall as it was, muft be proof of the importation of infeaion, that year, when greater numbers, in preceding years* are paffed over in filence ! In fuch accounts, there muft be want of knowledge, or want of honefty. The plague imported from Holland ! when the city of London had not been free from it, for 28 years preceding ! See the bills of mortality !— Befides, why in the name of common fenfe, fhould " two or three," infeaed perfons in 1664, fpread the plague over Lon- don, and defolate the city, when twelve, fourteen, twenty and thirty-fix infeaed perfons, who died in preceding years, produced no ill effeas ? To account for fuch effeas on the principle of in- feaion, is not poffible ; and men of fcience ought to be afhamed of fuch abfurdities. i9? in the fifth place, the fufpenfion of the difeafe, during fijfe weeks, is evidence, that infeaion had no agency in fpreading the difeafe. It is a faa known and acknowledged, that infeaion cannot be preferved, for a tenth part of that time in the open air. Air diffolves the poifon of any difeafe, in a very fhort time* Infeaion can only be preferved in confinement, as in clofe vef- fels or packages of goods. The walls of an infeaed houfe will be clean fed by the aaion of air, in a very few days, fo as to be perfealy harmlefs. During the fix weeks fufpenfion of the plague in London, where was the infeaion concealed to preferve it from air and froft ? Was the fomes fhut up by defign for a few weeks and then fet at liberty ? Had the perfons who were firft feized in Febru- ary, any accefs to the infeaed houfes or clothes of thofe who died in December ? Is this probable ? There is no fuggeftion of this fort. Then again another interval of feveral weeks elapfed from the death of thofe in February, before others were feized. It is not folely improbable ; but I aver, that the fomes or infeaing principle of no difeafe whatever, can be fufpended in a ftate of inaaion, in the open air, and afterwards give rife to difeafe. Unlefs therefore it can be proved that the perfons who died in April had accefs to infeaion, which had been clofely confined from the air, they could never have received the difeafe from the virus generated in February or December. Now it appears from the ftatement, that the perfons, feized in February, lived in a different part of the city, from thofe who died in December, and no fuggeftion that they had an intercourfe with any infefted objea. But the laft fentence of the ftatement difproves fully all affer- tions and fufpicions refpeaing infeaion. It feems that when the difeafe fhowed itfelf in fpring, it feized one here, and another there, in fcattered fituations, " without any certain proof of their having infeaed each other." This is ufually the cafe irr the plague, and in the yellow fever, in the ulcerous fore throat, the dyfentery and other contagious, epidemic difeafes. The whole myftery is, that any difeafe will firfl feize the conftitutions leg# 198 rapable of refilling that ftate of air, from which the difeafe pro- ceeds. One perfon will fuftain a vitiated air, for one day only j another for two days, and a third for a week, before his confti- tution yields to the deftruaive principle. It is precifely with the accefs of the plague, in a city, as with a company of men going from a healthy fituation, into a marfhy place—one man will be feized very fpeedily with the ague and fever; another will fuftain his health for a week or two, and fome perhaps ef- cape unaffeaed. This example explains the phenomena which attend the invafion of peftilence, as related by Evagrius, Die- merbroeck and others, and which will be more fully difcuffed in a fubfequent feaion. The account therefore of the origin of the plague in London in 1665, not only does not prove the difeafe to have proceeded from imported fomes, but aaually demonftrates the impoflibility of the faa. But we have better evidence than the popular accounts afford us, that the difeafe was generated in the city of London. Sy- denham has left facts on record, which place this point beyond controverfy. After defcribing the multiplied difeafes of increafed malignity, which prevailed in London, from 1661 to 1665, and which fwelled greatly the bills of mortality in that city, he informs us that in May 1665 he was called to aflift a woman of afanguina habit, who was feized with violent fever and frequent vomitings. He was furprifed at the Angularity of the fymptoms, and puz- zled to know how to treat the difeafe. The woman died the 14th day. He obferved her face, during the fever, to be red, and that a little before her death, a few drops of blood iffued from her nofe. Thefe and other circumftances fuggefted to him the ufe of bleeding, and his next patient recovered. This fpecies of malignant fever foon fpread and towards the clofe of May and beginning of June, became epidemic. Soob after appeared the true plague with its charaaeriftic fymptoms. After ftating thefe faas, Sydenham fays, " Whether the fever under confideration deferves to be entitled a plague, I dare not pofitively affirm; but this I know by experience, that all whe 199 were then feized with the true plague, attended with all its pe« culiar concomitants, and for fome time afterwards, in my neigh- borhood, had the fame train of fymptoms, both in the beginning and through the courfe of the difeafe." He then obferves that he attended fome perfons with the true plague, and afterwards, he faw feveral cafes of a fimilar fever. See chap. a. feet. 2. Had not the faculty been blinded to truth by their theory of fpecific contagion, it would not have been poffible fb long to over- look the progreffivenefs of the plague, which not only Sydenham, but many phyficians of the 16th and 17th centuries obferved and recorded. The malignant difeafes which prevailed from 1661 to 1664 marked a peftilential flate of air in London. We now know what Sydenham could not know, that this unhealthy ftate of air extended not only over Europe, but over Perfia and America. But the malignant fever which appeared in May, as defcribed by Sydenham, was the firft flage of the plague, or mild form of the difeafe, which always precedes that ftate of it which is char- aaerized by buboes. This form of the difeafe appears before the feafon or ftate of the atmofphere is advanced fufficiently to give the deftruaive principle its full force. • The fame fpecies of fever preceded the terrible plague in Ve- nice and in Naples, as before related; and this is always the caufe of uncertainty and controverfy refpeaing the nature of the difeafe, at its commencement. And it is remarkable that this milder form of the plague, often rages for many months, before the difeafe arrives to its crifis. Thus in London, the peftilen- tial principle produced a few cafes of real plague, in the winter of 1664-5, ^he cafes muft have occurred in conftitutions more irritable, or fufceptible of the caufe, than bodies in gene- ral ; or the perfons muft have been expofed to the aftion of pow- erful local caufes, or to extreme debility. The fevere froft doubtlefs fufpended the operation of the peftilential principle-— but on the opening of fpring, the operation began, and pro- ceeded from the malignant epidemic of May to produce the moft deadly effeasf aoo I have one obfervation further to make on this fubeja. It has been alledged and generally admitted that the plague was intro- duced into Amfterdam, in 1663 by a veffel from the Mediter- ranean. It is probable that if this queftion could be fully can- vaffed, the popular belief would appear to have had no better foundation, than many opinions in America, in regard to the importation of the yellow fever, which are proved to reft merely on conjeaures, fuppofitions, and vague reports. But in regard to the origin of the peftilence in Holland, in this inftance, it is wholly immaterial, whether popular opinion was well founded or not; for we have the exprefs authority of Diemerbroeck, that anterior to the arrival of the fhip, with the fuppofed infec- tion, the plague broke out in Heufden, a town on a branch of the Meufe, furrounded by a morafs, not a maritime place. Be- fides the fpotted fever, which precedes the plague and turns into it, had been prevailing in all parts of Holland in the preceding year. The peftilence therefore originated in Holland, before the infeaion arrived; and the tales of importation vanifh in fmoke. According to the bills of mortality, London loft upwards of 68,000 inhabitants by the plague in 1665, aad more than 28,000 by other difeafes. As the 28,000 deaths by common difeafes muft have occurred moftly in the fix firft months of the yeart before the plague raged, this circumftance fhoWs what a great increafe of mortality preceded the plague. With fuch evidence, before their eyes, how can difcerning men look abroad for the fo«rces of the malady ! It fhould alfo be remarked that this calamity among the hu- man race was preceded by a great mortality among cattle in 1664, It muit not pafs unobferved that the fummer of 1665 in Eng- land was very temperate, the weather fine and the fruits good, All the writers of that day agree, that no caufe of peftilence could be obferved in the vifible qualities of the feafon. This was the laft plague that has appeared in London, or in Great Britain. The difappearance of the plague in that and other countries, is a moft confoling faa, and one that has not a little engaged the minds of philofophic men, to difcover the sot Baufe. The caufes ufually afligned are, the deftruaion of the pity by fire in 1666, the more airy, convenient conftru&ion of the modern city, the introduaion of frefh water, with more cleanlinefs, and improved habits of living. Thefe reafons would have more weight in my mind, if th$ other large cities in England, in France, Spain, Holland and Germany, which have neither been burnt nor improved in their general ftruaure, had not alfo efcaped the ravages of peftilence. But as the plague has not vifited Paris and Amfterdam, which retain their ancient copftruaion, no more than London, which has been improved, we muft refort to other circumftances for the caufes of this exemption. The confideration of this fubjea will fall under another part of this work. In 1666, appeared a comet, the fummer was very hot, and a tremendous hurricane, tore up a thoufand trees in Nottingham foreft, and of 50 houfes in one village, feven only were left ftanding. In this tempeft fell hail-ftones, as large as hens eggs. An earthquake occurred in Oxfordfhire. Perfia did not efcapa the effeas of this peftilential conftitution. In 1667 prevailed famin and epidemic difeafes, and an earthquake demolifhed great part of Teflis, the capital of Georgia, and four villages, with the lofs of 30,000 lives ; and another city with the lofs of 2,000 lives. Chardin's travels, 86, 12& In 1666 dyfentery prevailed over England and many parts of Europe and in St. Domingo. This difeafe feems to be the fuc? ceffor of the plague, and other epidemics. During the inflam- matory ftage of an epidemic conftitution, evidenced by meafles, influenza, a mild fmall-pox, we rarely hear of deftruaive dyfen- tery. But after thofe difeafes have run their courfe, dyfentery appears in maqy parts of a country, and fometimes becomes aU moft univerfal. It would be a curious queftion, by what means the inflammatory diathefis, fo to fpeak, of the epidemic period, acts upon the nerves, mufcles and inteftines, to give to the fub- fequent autumnal fevers this particular direaion. During the foregoing feries of epidemics in Europe, America dj4 not efcape. Slight fhocks of earthquake were felt in 1660, B b 202 and in 166^. Great ficknefs prevailed at this period alfo, but I am not informed of the fpecies of diforder, except the fmall- pox in Bofton in 1666. In 1668, appeared a comet with a ftupendous coma. This was attended by an exceffively hot fummer, and malignant di£ eafes in America. In New-York the epidemic wasfo fatal, that a faft was appointed in September, on that account. This was undoubtedly the autumnal bilious fever in its infeaious form. In this fame year was an earthquake in America, and a meteor in the weft, in form of a fpear, pointing towards the fitting fun, which greadually funk and difappeared. Neal's Hift. vol. 1. 367. Magnal. b. 4. 184. ' This year was marked alfo by violent earthquakes in Europe and Afia. The winter of 1668-9 was verv fevere, and ice was feen in the Bofphorus ; that of 1670 covered the Danube with a bridge of ice. In winter appeared in Hungary two mock-funs of refplendetlt brightnefs—the infallible forerunner of great difcharges of elec- trical fire, or ot violent tempefts.—On the nth of March 1669, the eruption of Etna which had commenced in 1664 redoubled its fury, and by immenfe difcharges of lava laid wafte the coun- try below. Its violence fubfided in July ; but tremendous hurri- canes marked the year. The fummer of this year alfo was ex- ceffively hot. In this year, the cats in Weftphalia died with an eruption on the head, accompanied with drowfinefs. In England prevailed a dangerous fever, with flimy tongue and fore mouth. In Norway prevailed meafles of a malignant kind, attacking old and young. Bonetus, Med. Sept. 223.—In the two fol- lowing yours meafles was epidemic in London alternating with the fmall-pox.—See Sydenham.—In 1673 winter was cold ; and catarrhs were frequent with fpotted fevers—A comet appeared in the preceding year. In 1675 a wet and cool fummer, the influenza prevailed in Europe with the ufual fymptoms. In Italy was feen a meteor or fire ball, from the north-eaft ; and the following winter in America was colder than ufual. 203 The fummer of 1676 in England was cold. Meafles and fmall-pox prevailed in fome places. In 1677 was feen a comet in April and May; an earthquake was experienced in England ; and in Charleftown, Maffachu- fetts, raged the fmall-pox with the mortality of a plague. Mag. b. 4.189. The fummer of 1678 was very hot and dry. There was a comet and an earthquake in Lima. Fevers and affeaions of the throat were epidemic in the north of Europe. The plague raged with moft defolating fury in Algiers and Morocco. Authors re- late that four millions of people perifhed, and that the wafte of population has not fince been repaired. Cheniers Morocco, vol. 2. 180. On the 12th of January occurred in England a moft extraor- dinary darknefs, at noon. Notwithftanding the barrennefs of my materials, this peftilen- tial period may be very clearly diftinguifhed, by the meafles from 1669 to 1672 with the fmall pox, the catarrh of 1675, the fubfequent malignant fevers and affections of the throat, and finally the peftilence of 1678. The fame deleterious principle extended to America. Our annals relate that the feafons were unfavorable and the fruits •Wafted, while malignant difeafes prevailed among the people* The ficknefs and bad feafons were attributed, by our pious an- ceftors, to the irreligion of the times, and to their difufe of fall- ing. On this occafion, a fyhod was convened to inveftigate the caufes of God's judgments, and to propofe a plan of reforma- tion. The fmall-pox prevailed at Bofton in 1678, and a fingu- lar epidemic in England, France and Holland. See Neal's Hift. N. Eng. vol. 2. 3 a. Mag. b. 5. 85. Hutch, vol. 1. 324. Doug. vol. 1. 440. Short, vol. 1. The comet of 1678 was followed by a very cold winter, after a rainy autumn, with an epidemic cough. A comet is mention- ed in 1679, and the plague was in Vienna. The year 1680 was diftinguifhed alfo for a fevere winter, and the noted comet that had appeared in Juftinian's reign. In Drefden raged the plague. The ftimmer was hot and fickly. 2d4 A large meteor was feen in Germany, defcending to the north and leaving behind it a long luminous ftream. The fummer of 1681 was exceffively dry. This was the forerunner of violent earthquakes, which, in 1682 fhook all Germany, Italy and Switzerland. In fome places, the fhocks were preceded, for four nights, by lights or flame, like ignes fatui, oh the mountains. The cohvulfions were attended with a-difagreeable fulphurous fmell. In this year alfo was vifible a comet, and an eruption took place, both of Etna and Vefuvius. In this year 1682 a mortal difeafe fpread among the cattle in fctaly, Switzerland and Germany, that was called the angina ma- ligna, and of which cattle died in 24 hours. Authors relate that a blue mift appeared on the herbage of paftures. The dif- eafe moved about two German miles in 24 hours, and fpread Over Germany and Poland. Cattle at rack and manger were affeaed equally with thofe that grazed. At Halle in Saxony prevailed the plague ; and at Dublin, a petechial in which the brain was feverely affeaed, and bleeding pernicious. The difcharges of fire already mentioned were produaive, as ufual, of violent winds. In Sicily, a tempeft, preceded by great darknefs, almoft laid wafte the ifland. In 1683 was an earthquake in England, in September, pre- ceded by meteors or lights and fetid exhalations. A comet ap- peared in this year, and another in the following. The winter of 1683-4 was the coldeft that could be recol- Ieaed by the oldeft men living. Trees of large fize fplit with the froft. The fame winter was exceffively fevere in America, and from a paffage in a letter of the Rev. John Eliot, the fea- ion appears to have been fickly. Hift, Col. vol. 3. The year 1683 was alfo remarkable for general ficknefs in Conneaicut, and in fome places, unufual mortality. Some towns fuftered by exceflive rains. Trumbull's Hift. p. 383^ Thefe unufual feafons were accompanied with fingular difeafes. In Leyden in 1683 prevailed what was called the hungry fever, which came on with a chill, fucceeded by ravenous hunger, 2cr$ To gratify this appetite was fatal. When the hot fit eame oft^ the hunger fubfided. In 1684 was a terrible earthquake in St* Domingo. Defcription of St. Domingo, vol. 1. 14a. After the fevere froft in 1684, a malignant dyfentery raged over Europe. This and the two fucceeding fummers were hot and dry. In 1685 Languedoc in France was overrun by grafs- hoppers, and the petechial fever was prevalent. In September 1686 was feen a comet. At Lille in France, fell a ftorm of hail, the ftones of which were of a pound weight. There was an eruption of Etna, in this year alfo, and a meteor was feen at Leipfick on the 9th of July, which was ftationary for 7 minutes, at the height of 30 miles. It is curious to re- mark the coincidence in time between the phenomena of the elearical fluid, tempefts, fnow and hail. The fummer of 1687 in Europe was very rainy. In Oao- ber the city of Lima in Peru, was demolifhed by an earthquake. The winter of 1688 was cold, and in the fummer following epidemic catarrh fpread over Europe. This was preceded by a difeafe of the fame fpecies among horfes, attended with a de- fluxion of rheum from their nofes. Swarms of infeas in fome countries announced a peftilential period. In the interior of Germany were fome dyfenteries. An earthquake was experi- enced at Naples, and Smyrna was laid in ruins. In 1689 appeared a comet, and .both Etna and Vefuvius dis- charged fire. The autumn was very rainy, and the fpotted fe- ver prevailed in fome parts of Germany. In Bofton the fmall- pox was epidemic. In 1690 the fummer was rainy, frogs were in unufual numbers in Italy, and corn was cut fhort by mildew. Rainy feafons gen- erally fucceed great eruptions of volcanoes and earthquakes. The year 1691 commenced with fevere froft, followed by a hot dry fummer. The fpotted fever prevailed in Italy, in which bleeding was fatal. There was alfo great mortality among cat- tle and fheep. The feafons in this year were peculiarly unfavorable in Amer- ica, altho I am not able to defcribe them. It appears from the journals of the affembly of New-York, that upon an addrefs of 2o5 the houfe to the governor and council, a monthly faft was ap- pointed to be obferved from September 1691 to June 1692 ; the fpecial reafons afligned for which were, " a burthenfome war, and a blaft upon the corn." This is a remarkable faa, and not unfrequent, that at one and the fame time, the powers of veget- ation fail in the moft diftant parts of the earth. Perhaps we fhall be able to account for this inftance of a deranged ftate of the elements by the univerfal explofions of fire in the two fol- lowing years. St. Domingo experienced a fevere earthquake in 1691, in the year of this blaft on the corn, Defcription of St. Domuigo, by Moreau St. Mcry, vol. 1.142. On the 7th of June 1692 after a feries of dry, hot, calm weather, a moft dreadful earthquake fuddenly funk the town of Port-Royal in Jamaica, and demolifhed moft of the buildings on the ifland, with the lofs of 2000 lives. After the earthquake, the heat was ftill more intenfe, mufquetoes were innumerable* and a malignant fever fell upon the inhabitants in all parts of the ifland, with which 3000 perifhed. In the fame year, a fimilar difeafe invaded Barbadoes, and affliaed the ifland for many years. Indeed the whole world was fickly. On the 8th of September England, Holland, France and Germany were convulfed by an earthquake, and Switzerland felt a fhock in Oaober. In the fame year was an eruption of Etna, and great fnows followed. The fpotted fever continued its ravages; and it was remarked to be much more malignant and fatal in the wane of the moon. During an eclipfe in 1693 *he hxk almoft all died. The difeafe was more fatal in town than country. I have no account of the difeafes in Egypt or the Levant, during this period ; but it will be found on examination that great peftilence raged in thofe places, about this time, or between i6Sg and 1693. On the 10th of January 1693 happened a moft terrible earth- quake in Sicily and Naples. On the preceding evening, was obferved a great flame or light, apparently at the diftance of an Italian mile, and fo bright as to be miftaken for a fire. The fpeaators attempted to approach it; but it appeared ftill at the loy fame diftance. As foon as the earth began to fhake, the flame difappeared. It is not within my limits to enumerate the miferies occafioned by this concuflion of the earth. Suffice it fay that many towns were laid in ruins and 6o,ooo people perifhed. During the con- vulfion a fountain difcharged its waters as red as blood. This calamity was preceded by a ferene flcy, and followed by dark- nefs or vapor of a reddifh or yellow hue. The effeas of this earthquake were remarkable on the human body. Among thefe were malignant fevers, fmall-pox fatal among children ; madnefs, dullnefs, fottifhnefs and melancholy, with deliria and lethargy. Are not thefe effeas produced by an excefs of ftimulus, occafioned by the fuperabundance of elearicity ? The fummer following this convulfion of the earth, was in« temperately wet and cool, and corn was mildewed. Another account fays the fummer in Italy was very hot and dry. The (potted fever, and in fome places dyfentery were very mortal* Wounds degenerated.into ulcers, and blifters were followed by mortification which proved fatal to many.. In this year alfo Etna in Sicily, and Heckla in Iceland dif- charged fire and lava ; a new volcano was opened in Afia, and an ifland, called Sorea, near the Moluccas, was ruined by its volcano. Moft dreadful ftorms marked the fame year; one in America, on the 19th of Oaober, was memorable for its violence. An epidemic catarrh began in Europe in Oaober, being pre- ceded by a fimilar difeafe among horfes. The preceding winter was probably very mild in America; for on the 13th of February, Gov. Fletcher, with a-body of / Sroops, failed from New-York for Albany. Smith's Hift. New-York, 82. In 1693 the feamen and foldiers, under Sir Francis Wheeler, who wa6 fent to conquer Martinico, were feized with the plague of America, and three fourths of them perifhed. Hutchinfon, wol. 2. 72, relates that this fleet came to Bofton and introduced the difeafe into that town, where it occafioned a deplorable mor- tality. Douglas relates the fame faa, i©8 This account feems to be conmdiaed by Mather, in his Mag- nalia, b. i. 22. In a fermon delivered on leaure day, April 7, 1698, it is afferted in fo many words, that " An Englifh fquadron hath not brought among us the tremendous peftilence, under which 9. neighboring plantation hath undergone prodigious defolations. Bofton, 'tis a marvellous thing a plague has not laid thee defolate." By comparing the date of this fermon, with other events re* lated in it, I find there is no miftake in the date ; and as the author lived in Bofton, and was cotemporary with thefe events, and perfonally acquainted with Sir Francis Wheeler, I conclude it was not Bofton, but fome other fea port town, which fuffered by the arrival of a fleet. In the 2d book of Magnalia, p. 71, the fame author men- tions this expedition and the terrible mortality. He fays the- diftemper was " the moft like the plague, of any thi«g that had ever been feen in America, whereof there died before the fleet could reach to Bofton, as I was told by Sir Francis himfelf, 1300 failors out of 2100, and 1800 foldiers out of 2400." In book 7. 116, the fame author fays, " there was an En- glifh fleet of our good friends with a direful plague aboard in- tending hither. Had they come, as they intended, what an horrible defolation had cut us off, let the defolate places, that fome of you have feen in the colonies of the fouth, declare unto us. And that they did not come was the fignal hand of heaven." This paffage is in a leaure preached on the 27th of September, 1698, From this authentic hiftory, written by a cotemporary clergy- man, we infer that Hutchinfon muft have made a miftake. Sir Francis Wheeler's fleet arrived at Bofton, moft dreadfully in* feaed, but no difeafe was propagated in Bofton. Some other fleet, it feems, had introduced the difeafe into a " colony of the fouth," perhaps Newport or New-York, but I have no in- formation on the fubjea. The great difcharges of fire and earthquakes of 1693, were followed, as ufual, by an intenfely cold winter. The fucceed- ing fummer of 1694 was hot and exceffively dry in Italy, tilt Oaober, when the earth was deluged with rain. 209 In May was a violent earthquake and volcano in Banda, an ifland in the Indian feas. Fire iffued from the neighboring feas, the air was impregnated with the fmell of fulphur, and ficknefs prevailed. An eruption of Vefuvius happened the fame year, and violent earthquakes in Sicily and Calabria. In this year the agitations of fire feem to have fubfided ; and as ufual, a feries of rainy cool fummers fucceeded, in which corn perifhed or was blafted, crops failed, and univerfal dearth enfued. One of the moft remarkable effeas of the late agitations of the elements, was the frequency of apoplexies in Italy. So common were they in 1695, as to be called epidemic, and oc- cafion general confternation. This is not an infrequent confe- quence of the high excitement that takes place in peftilential times, ending in extreme debility in the brain. Something of this kind has been obferved in America, within the laft few years. I have very few faas in regard to the feafons and difeafes in America, during this period, from 1689 to 1695. It appears however that the diforders of the elements were experienced in America. In 1695 prevailed a mortal ficknefs among the Indians in the eaftern parts of this continent. Hatch, vol. 2. 8.7. A contagions fever prevailed in Bermuda, the fame year. In Europe many malignant fevers prevailed, but no epidemics, except meafles and chin cough of a bad type. In Ireland ap- peared oftenfive fogs, a thick clammy dew on the herbage, of a, yellow color, and confiftence of butter. A fimilar fubftance was obferved at Middletown, Conneaicut, on the morning after the earthquake, May 17, 1791- The year 1696 was cool and wet—fummer in Britain, refemp bled winter, and winter was like fummer. Corn was mildewed, Dyfentery fatal among children. In America the winter of 1696 7, according to Hutchinfon, was very fevere. Loaded fleds paffed from Bofton to Nantafket. Food was fcarce and loffes at fea very great. I am not without fufpicions however, that the author has here defcribed the fol- lowing winter, which was as fevere as he has reprefented it. C c 2 I© In 1697 the weather in Europe was moftly cool. An earth- quake at Lima in Peru fhook the country with terrible violence. In a diary kept by Daniel Fairfield, of Braintree, in Maffa- chufetts, an unlettered man of good underftanding, I have a particular defcription of an influenza that prevailed in America in the fevere winter of 1697-8.* This catarrh began in No- vember and prevailed till February. Its violence was in Janu- ary, when whole families were fick at once, and whole towns were feized nearly at the fame time. It appears to have been an epidemic of the fevere kind ; and the epidemics which fol- lowed it in America were of correspondent feverity. In the fame winter a mortal difeafe raged in the town of Fairfield in Conneaicut, which was fo general, that well per- fons could fcarcely be found to tend the fick and bury the dead^ Seventy perfons were buried in three months, altho it may be doubted whether the town then contained 1000 inhabitants. M. S. letter from Dr. Trumbull. In the fame winter raged a deadly fever in the town of Dover, in New-Hampfhire. M. S. of the Rev. John Pike. This difeafe was doubtlefs that fpecies of inflammatory fever, attacking the brain and ending in typhus, which has often pro- ved a terrible fcourge to particular parts of America, during the rage of peftilence in the eaft, and of other epidemics in this country. We fhall hear of it in the following century, and efpecially in 1761. On the 20th of June 1698 the town of Latacunga, in the province of Quito, nearly under the equator, was laid in ruins by an earthquake, as were Riobamba, Hambato and other towns in the fame diftria. In one place a chafm of five feet broad and a league in length, was opened, and on a mountain happened a volcanic eruption, from which iffued afhes, cinders and flames* Ulloa, vol. 2. * For this and many other articles of intelligence, I am indebted to the late Dr. Jeremy Belknap, whofe value as a man and as a hiftorian many years friendfhip and correfpondtnee had taught me to appreciate, and whofe lofs to fociety and the republic of letters, I moft deeply la- ment. £I« . The malignant fever already mentioned, whatever might have been its precife fymptoms, was foon followed by more general ficknefs. In 1699 raged in Charlefton South-Carolina and in Philadelphia, the moft deadly bilious plague that probably ever affeaed the people of this country. Mr. Norris of Philadelphia has kindly favored me with 2 Gght of a number of M. S. letters of his grand-father Ifaac Norris, written during the ficknefs, to his correfpondents. This worthy gentleman was then in trade, and well acquainted with the faas refpeaing the difeafe, as his own family fuffered a lofs of feveral of its members. In a letter dated Auguft 15, 1699,- he mentions, that a ma- lignant fever broke out about the beginning of Auguft, which he defcribes as the " Barbadoes diftemper," tho he gives no intimations of its being communicated from countries abroad by infeaion. He fays the patients " vomited and voided blood." On the 24th of Auguft, arrived the Britannia from Liver- pool, which had been 13 weeks on her paffage ; fhe had 200 paffengers on board—had loft fifty by d«ath, and others were fickly. September ift, he writes that the diftemper appeared to abate at one time, but afterwards revived. He mentions the fummer to be the hotteft he ever knew ; men died at harveft in the field. All bufinefs in the city was fufpended. During the yearly meeting the difeafe abated, but the meeting was thinly attended. Afterwards the difeafe returned in all its violence. Oftober 9th, he writes that he had hoped the cool weather would have relieved the city, but it did not. Oaober 22d, the difeafe had abated. Of this epidemic, died two hundred and twenty, of whom eighty or ninety be- longed to the fociety of friends. The population of Philadelphia at this time, is not exactly afcertained ; but as the city had been fettled but feventeen years, the number of people could not have been great. If we.con- fider that the city was thinly inhabited, and that no confidera- ble artificial caufes of difeafe had been accumulated; together 412 with the fact of the patient's vomiting and voiding blood,-we muft admit the difeafe to have been extremely virulent, beyond any thing that has marked its returns in fubfequent periods. In the fame letters, Mr. Norris, Oaober 18th, mentions that he had information from Charlefton of the great mortality by the fame fever—150 had died in a few days, and the furvivors moftly fled into the country. In a hiftory of South-Carolina, lately publifhed, there is a more particular account of the calamities that befel Charlefton in this year 1699. A moft dreadful tempeft, a common event after exceflive heat, threatened a total deftruaion of the town. The fea fwelled and lufhed violently into the town, compelling the people to fly to the tops of theit houfes for fafety. A fire broke out and laid moft of the town in afhes. The fmall-pox proved fatal to many of the youth, and to fill the cup of calam- ity, the bilious plague broke out with fuch irrefiftible mortality, that the principal officers of government, one half of the mem- bers of affembly and multitudes of the citizens fell viaims.. Thefe calamities came near to diffolve the fettlement. Hift. of S. Carolina, vol. 1. 142. I find no fuggeftion that any veffels had arrived from the Weft- Indies at thefe places, or that any fufpicion exifted of the im- portation of this terrible difeafe. At that time, there was very little intercourfe direaly between Philadelphia orCharlefton and the Weft Indies. But it will be remarked, that the difeafe firft appeared about the " beginning of Auguft," as in modern times—that it once abated, as it did in New-York, both in 1795 and 6, fo as to be extinguifhed in the latter year, and that for two or three weeks.—That in 1699 as in later returns of it, it yielded not to cool weather, until late in Oaober. It will be further re- marked, that a fevere epidemic catarrh preceded this plague, about eighteen months, as it did in 1789-90. During thjs period, other parts of the earth did not efcape affliaion. A comet appeared in 1698 and another ftnail one ib 1699 ; and in this latter year, Lima fuffered confiderable damage, by an earthquake, as did fome parts of Batavia in the Eaft-Indies. In Oftober 1698 began a fatal fpotted fever to prevail over all England.' In the fpring of 1699 a fevere and fatal catarrh was epidemic, which carried off the young and robuft, together with hard drinkers. A cough was epidemic among horfes in England and France. In this period the catarrh in America preceded that in Europe, one whole year. The feven laft years of this century, the period under con- fideration, were diftinguifhed for a fevere and continued famin in Scotland. The general caufe was, the wet and cold fum- mers which prevented crops from-arriving to maturity. Vaft multi- tudes perifhed with hunger—the dead bodies lay fcattered along the highways. See Sinclair's Statiftical account of Scotland in a great number of paflages, and efpecially vol. 6. 132, 189. It does not appear that, during this long period of diftrefs and want, any peftilence prevailed in Scotland. At the fame time, famin affliaed Finland and carried off one tenth of the inhabitants, and a greater proportion in the lefs fertile provinces of Sweden. Williams's Obf. on North Governments, vol. 1. 638. The fame period was remarkable for failure of crops in A- merica. In a fermon preached in Bofton on Leaure Day, Sept. 27, 1698, we have the following account of this fubjea. " The harveft hath once and again grievoufly failed, in thefe years, and we have been ftruck through with terrible famin.—- The very courfe of nature hath been altered among us; .a la- mentable cry for bread, bread, hath been heard in our ftreets." Magnalia b. 7. 113. In the preceding page, of this fermon, it is alfo remarked, that " Epidemical fickneffes have, in thefe years, been once and again upon us," and it is mentioned that Bofton loft, in one year, fix or feven hundred of its people, by one contagious dif- eafe. The year is not fpecified. It will be obferved that in the hiftory of the laft two centu- ries few inftances of the plague in Egypt and the Levant arc mentioned. The reafon is, that I have no regular feries of ac- counts of plague in Egypt or Conftantinople, for the laft two ot three hundred years. One remark however I will hazard, oa 214 the ftrength of fafls within the prefent century, that whenever malignant epidemics prevail generally in Europe or America, the plague rages in Egypt and Conftantinople, or rather a little before ; the commencement of the peftilential ftate of air in thofe unhealthy cities being a little anterior to its principal ef- feas in the north of Europe. At the time of the dreadful bilious plague in Philadelphia and Charlefton juft before defcribed, the plague was raging in *the Levant, and for a year or two after. During this period, in 1700, the fame peftilential conftitu- tion difplayed itfelf in a moft deftruaive fore throat in the ifland of Milo, in the Levant. It is thus defcribed by Tournefort, toI. 1. let. 4. He fays it appeared in a " Carbuncle or plague- fore in the bottom of the throat, attended with a violent fever." It Carried off children in two days, but fpared adults. He calls it the " child's plague." There appears to be fome pro- piety in giving the difeafe this appellation. It has fome refem- blance to the true peftis, the ulcer being formed in the throat in- ftead of the glands. The infidioufnefs of the diftemper is another circumftance of refemblance—perfons in both. difeafes often walking about, a few hours before they expire. But this is a moft prominent faa, that the ulcerous fore throat, or ma- lignant anginas are rarely or never epidemic, except in periods when the plague and yellow fever prevail in places where they ufually appear. In no inftance has the fore throat been epidemic 'in America, except when the plague has been raging in Egypt and Conftantinople. At leaft I can find no exception to this remark ; and what is more, the virulence of the one difeafe in one country, corresponds with the malignity of the other difeafe in the other countries. Thus, as the plague in Egypt in 1736, was far more deftruaive than the fame difeafe, at other times, fo was the angina maligna of that period in America. When obfervation and philofophy fhall prevail over the preju- dices of men in regard to the origin of thefe difeafes from in- feaion, it will be found that the angina, in its various forms, is only a particular ftage or modification of the peftilence, which fpreads over the world at certain unequal periods. The milder 2*5 forms of the peftilence appear in catarrh, meafles and chin cough; which ufually appear together, or nearly fo, at the beginning of the more virulent general contagion ; the later and more fatal ftages are marked by anginas, cynanche maligna, petechial fe- ver, bilious and glandular plague in fummer; and peftilential pleurifies in winter. There are certain times, when the conftitutions of men in all parts of the world, contraa a poifon, which nature makes an effort to expel; and the different epidemics that accompany or follow each other, in rapid fucceflion, appear to be the differ- ent modes by which nature ftrives to rid the human body of the virus. Thefe modes depend on the feafon of the year, the con- ftitution or age of the patient and a multitude of fubordinate circumftances.—Whether this poifon is a pofitive fubftance in- haled by the lungs and pores, or is the effea of mere debility, which unfits the feveral parts of the body to perform their func- tions, is a queftion of a curious nature. It is remarkable that in this year 1700, when this ulcerous fore throat was raging in the Levant Ifles, fmall children in the north of Europe were feized with a fuffocating catarrh or catarrh- ous fevers. Thefe were followed by mild epidemic meafles. Short vol. i. 418. In the fame year the fmall-pox was confluent and malignant. The winter of 1700 was very mild. In this year fell a meteor in Jamaica, which entered the earth, making confiderable holes, fcorching the grafs, and leaving? fmell of fulphur. Bad. Mem. 6. 380. 2l6 SECTION VII. Hiftorical view of peftilential epidemics from the year 1701 to 1788. JL HE year 1701 appears to have been exceffively dry in America. Dr. Rufh relates that during the dry fummer of 1782, a rock in the Skuylkill appeared above the furface of the water, on which were engraven the figures 1701. How little do men fufpea the value of this infcription ! To this alone I am indebted for the faa of extreme drouth in that year—and the faa is among the proofs of an extraordinary evaporation, before dif- charges of fire and lava from volcanoes. In 1701 was an erup- tion of Vefuvius ; in 1702 of Etna. It will hereafter appear that a fimilar dry feafon in 1782 preceded the great eruption of Heckla in 1783. Indeed it is a general faa, and as far as I can learn, fuch feafons feldom occur, except during the approach of comets, or antecedent to volcanic eruptions. This was a peftilential period. In 1701 Toulon loft two thirds of its inhabitants by the plague, and the Levant was fe- verely affeaed about the fame time. See the bills of mortality for Augfburg, Drefden and Bofton. In 1702 appeared a comet; Etna difcharged its fires, and in Bofton raged a malignant fmall-pox, attended, in many cafes, with a fcarlet eruption, which was miftaken for the fcarlet fever. It appears from Fairfield's diary that this difeafe appeared in June and was at firft mild, not fatal to any of the patients. Iq Auguft died one patient—in September it became very mortal, and in this month was attended with a " fort of fever called fcarlet fever." In Oaober, many died of the " fever and the fmall-pox, and it was a time of fore diftrefs," on which account the general court fat at Cambridge. In December " the fever 217 abated ;" but the fmall-pox continued to be mortal, till the month of February 1703, when it began to fubfide. I have already remarked that eruptive difeafes feem to belong to one family. Phyficians will obferve the alliance in their fymp- toms ; but I would obferve that the progreflivenefs in this difeafe of 1702 and the variations in its fymptoms, prove it to have been an epidemic, and not the effea of mere infeaion, or fpe- cific contagion. In this year alfo the drouth was extreme. In New-York rag- ged the American plague, which was faid to have been imported from St. Thomas's. By the accounts, this was more fatal than any difeafe fince that period. It was called the " Great Sick- nefs" and hardly a patient furvived. On account of it, the affembly was held at Jamaica on Long-Ifland. Smith'a Hift. N. York, p. 104. Journals of AlTembly, vol. 1.151. Such were the epidemics in America which followed the in- fluenza of 1698—malignant pleurifies in 1698—plague in 1699 and in 1702, with virulent fmall-pox—all of unufual feverity. Let the reader compare thefe faas with the accounts from Eu- rope and the bills of mortality. The winter of 1702-3 was variable—fevere froft and great fnows, with intervals of warm weather. In fpring catarrh prevail- ed in England, followed by a fickly fummer, with earthquakes. In January and February 1703 were fevere fhocks of earth- quake in Rome, Naples and other parts of Italy. In Oaober a memorable tempeft or hurricane, which did great damage at fea, and injured buildings on land. In 1704 the fummer was very dry, and a moft malignant fpotted fever raged in Augfburg and in Pruffia. Flies were in great abundance, and there was an eruption of Vefuvius. The laft eruption of the volcano in Teneriffe was in this year, fince which it has difcharged fmoke, but no fire. Note. A late arrival from Teneriffe brings an account of the burfting forth of a volcano, in June laft, which continued, till the vefftl left the ifland in Aaguft. In December 1705 were many moft violent tempefts and in- iindations. The tide rofe in the Loir in France 25 feet beyond D d 2l8 its ufual height. Half of Limerick in Ireland was laid under water. Thefe ftorms indicated the approach of a comet, which appeared in the following year. In 1706 coughs and coryzas prevailed, and dyfentery fatal among children. A fmall fhock of earthquake was felt in America in 1705. In 1707 appeared another comet and fubterranean fire was uncommonly agitated. Vefuvius difcharged fire, and a new ifland was thrown up in the Archipelago, with an earthquake and volcano. The feafons in this and the following year were variable. Buffon's Nat. Hift. In Npvember 1708 began a moft fevere and univerfal catarrh in Europe, which was fpeedily followed by a feries of peftilen- tial difeafes. Of this catarrh, of the feafons, and the plagues that followed we have from Europe very correa accounts ; but, with the utmoft induftry, I cannot learn whether the catarrh extended to America. The explofion of fubterranean fire in various places in 1707 feems to have been the commencement of this period ; altho there was a plague in the eaftern parts of Europe, moft of the preceding years from 1700. A meteor paffed over England, near the mouth of the Thames, July 31, 1708, a few months before the catarrh. The winter of 1708-9 was the fevereft that had happened, af- ter 1683-4. But it appears that the catarrh commenced two months before the fevere cold began. At leaft this epidemic appeared in the north of Europe, as early as November ; whereas the autumn was one of the mildeft, till January, that was ever known. Then the weather changed fuddenly to moft fevere cold and continued for a number of weeks. Short, vol. 1. Lancifius, p. 194 and feq. This catarrh is carefully defcribed by Lancifius as it appeared in Italy. In Rome it commenced in January, but increafed afterwards, as the cold abated. It began with coryza, rheumata and flight cough, and was attended with pains in the breaft, angina, pleurifies and peripneumonies, which prevailed greatly in the fpring, among thofe who negleaed the cough, or ufed a full diet. 219 Symptoms of this catarrh were, laflitude, fever with chills* wandering pains in the breaft, continued cough, hard pulfe> flame-colored or turbid urine, fpitting of blood and difficult ref- piration. The cheeks were red and the body fuffufed with a yellow color, like that of the jaundice. Perfons fhut up in prifon, efcaped the difeafe.* Fewer wo- men than men were affliaed, and perfons in eafy circumftances, who could take care of themfelves, fuffered lefs than the poor. Many recovered by means of fweats or hemorrhagy at the nofe, or difcharges from the bowels, or copious difcharges of urine, or by all thefe evacuations, accompanied by fpitting a thick phlegm. Venefeaion was beneficial, efpecially in robuft confti- tutions. On diffeaion, the precordia appeared of a reddifh color, extending to "the diaphragm—and difcolored by fpots of blackifh thick blood—polypuffes were difcovered in the great vef- fels of the heart. This difeafe did not entirely difappear till June. In the fummer of 1708 preceding the fevere winter and ca- tarrh, gnats appeared in prodigious fwarms. The winter of 1708-9 killed fruit-trees, vines and corn. After this exceflive cold, multitudes of people died of apoplex- ies, and others were feized with vertigoes, arthritics, pleurifies, inflammatory fevers of all kinds, and confumptions. This fe- verity of cold extended over America as well as Europe, in the lame winter. A peftilence raged in the north of Europe from the years 1702 to 1711, of which we have an account in Philofophical Tranfaaions, No. 337. Baddam's Memoirs, vol. 6. p. 5. It has been obferved already that the plague raged in the Le- vant, in the firft years of the prefent century. In 1702, the fame year, it will be noted, in which the terrible fmall-pox raged * This has been obferved in one or two inftances in America, and has been alledged as an evidence that the influenza is an infectious dif- eafe, and that perfons fequeftered from contagion, may efcape it. Te my mind the fact is rather an evidence that the efcape of prifoners is owing to a different, perhaps a lefs ftimulant condition of the air they breathe. It is hardly poffible they fhould efcape expofure to infection, when every one around them is affected. The contagion of the difeafe however is not denied. *L1' in Bofton and bilious plague in New-York, the plague broke out in Poland, near Pickzow, foon after an unfortunate battle be- tween the Swedes and Saxons. No fuggeftion appears that the difeafe was caught by infeaion from a diftant country, nor that the fetor of dead carcafes was fuppofed to generate the diftem- "jJeR, On thefe important points we are left in the dark. All that is recorded is, that it firfl began near Pickzow in Poland, foon after a battle. It fpread in 1703, 4 and 5 over Poland, and into parts of Hungary and Ruffia, fweeping away vaft num- bers of inhabitants. In 1706 we hear nothing of it. In 1707 it broke out in Warfaw, with great mortality. In 1708 it ap- peared in Thorn, and parts of Polifh Pruffia. This approach of the difeafe alarmed the people of Dantzick —public prayers were ordered in the churches—all commerce and communication with infeaed places were forbid—no mer- chandize from infeaed or fufpeaed places was.permitted to enter the city, and the magiftrates negleaed no meafure that could guard the public fafety. All travellers and ftrangers were ftria- ly examined, and none permitted to enter without fufficient proofs that they came from healthy and uninfeaed places. Thefe and other ftria regulations-were enjoined in July 1708; but notwithftanding thefe precautions, ** the diftemper gradually infinuated itfelf, for in March 1709, there died out of one dif- tria in the old town feven perfons, and another perfon, being illj was fent to the hofpital, where the difeafe foon fpread." Dr. Gottwald, the author of this account, vifited the hofpital on the l6th of the fame month, and found many perfons ill—" fome had buboes, others carbuncles, others gangrenous ulcers, which he could not determin to be peftilential, but which he judged to be fymptoms, if not of the plague already commenced, at leafl cf fomethlng, but little inferior to it, and certain forerunners of that deftruaive diftemper." In the preceding account, we obferve the utter infufficiency of laws and regulations to prevent the introduaion of the plag"ue into cities ; and the uncertainty of phyficians at firft as to the nature of the difeafe. The faas ftated prove the difeafe to have been generated on the fpot, and to have been progreffive from $21 malignant fevers to the real plague. I have no bills of the mOr* tality in Dantzick for the preceding years, but if any fuch are on record, it will appear, that the approach of the plague was indicated in that city by malignant difeafes and increafed mortal- ity, for fome months or perhaps a year or two preceding. The difeafe fpread flowly at firft, but in July and Auguft be- came general—it was at its height in September, and gradually declined till the clofe of the year. The number of viaims was nearly 25,000. From the very accurate hiftory of this peftilence by Dr. Gottwald, the following circumftances are to be colkaed. 1 ft. That the diftemper firft made its appearance in a part of the old town, called Raumbaum. What its fituation is, may be feen in Bufching ; a part of the city built on a ftream which falls into the Viftula—low of courfe—a place of bufinefs, and its ftreets dirty. 2d. The difeafe, after its firft appearance, lay lurking for a long time, in the fuburbs of the city, and its progrefs was not perceivable, for two or three months. This correfponds with its phenomena in London and other places ; and proves that cold or favorable weather fufpends or checks the aaion of the peftilential principle. 3d. It was moft fatal to the poor—people in good condition moftly efcaped. The fame was obferved at Copenhagen in 1711. 4th. Its decreafe was gradual, as well as its increafe. 5th. Many of the inhabitants, tho they took never fo much care to avoid the diftemper, kept at home, fuffered no infeaed perfon to approach them, and ufed all manner of prefervatives, " yet caught the infeaion.** 6th. The difeafe was preceded, in 1708, by extraordinary numbers of fpiders. The fame prefage has been obferved on other occafions. 7th. While this diftemper was raging, on the nth of Au- guft, an offenfive mift was obferved, like a thick cloud, but of fhort duration. It returned in the afternoon, from the north- weft, fo thick as to darken the air. Its color was that of the effluvia from the effervefcence of the oil of vitriol with oil of ♦artar, a blackifh yellow. 222 8th. In the oeginning of Oaober appeared over the city a blue fiery globe or meteor, which came from the north weft, in the night, fhot towards the town rapidly, illuminating the city, and fell to the fouth. 9th. Crows, fparrows and other birds did not make their ap- pearance during the peftilence. In 1708 and 9 the plague defolated Livonia. In 1710 the difeafe appeared in Sweden ; 30,000 perfons perifhed by it in Stockholm, and other parts of the. kingdom did not efcape. Hiftorians relate, that in the latter part of the laft century and beginning of the prefent, the fweating ficknefs and great plague in Sweden deftroyed feveral hundred thoufand lives, in confe- quence of which Sweden is lefs populous than formerly. Williams's Obf. vol. 1. p. 638. Univerfal Hift. vol. 35. 458. In 1710 alfo the territory of Lithuania was ravaged by pef- tilence. In 1711 Copenhagen loft 25,000 citizens by the fame mal- ady. It is proper to remark how extenjively peftilence prevailed af- ter the great catarrh and terribly fevere winter of 1709. Nor did America efcape the operation of the general princi- ple. A body of troops under Gen. Nicholfon, deftined to co- operate with a fleet from England, in the reduaion of Canada, encamped near Wood Creek in the province of New-York, and in July and Auguft were attacked with a diftemper which made dreadful havoc and obliged them to decamp. Some of the men died as if they had been poifoncd. This circumftance gave rife to a report which Charlevoix gravely relates, that the In- dians had poifoncd the water of the creek, by throwing into it all the fkins of beafts they had taken in hunting. The difeafe was probably the lake fever or a malignant dyfentery. This happened in 1709. Hutch. Hift. Maff. vol. 2. 179. England alfo felt the influence of the fame general principle, as appears from the bill of mortality for 171 o. In France, v England and the Low Countries raged a catarrhous fever to 223 which was given the name of Dunkirk rant. In fome places prevailed a fpotted fever, as at Norwich. Short on Air. Baddam's Mem. vol. 6. 70, 73. In 1712 prevailed catarrh in Europe, with fore throats. Whether catarrh prevailed in America alfo, I can obtain no in- formation. The feafons in England were exceffively wet, and corn was rotten or mildewed. The winter was fevere, there was an eruption of Vefuvius and an earthquake. From thefe circumftances, I fufpea the approach of a comer, but have found no account of any.* Short, vol. 2. 8. In Oaober 1712 commenced a mortal ficknefs in the town of Waterbury, in Conneaicut, which raged for eleven months. It wasfo general that nurfes could fcarcely be found to t^ndthe fick. What the difeafe was, I am not informed ; but not im- probably it was that fpecies of putrid pleurify, which has fo of> ten made dreadful havoc in America. Trumbull's Hift. of Connecticut, 386. In the fame year, prevailed a fore throat in London, accom- panied with dizzinefs and pain in the limbs. In 1713 prevailed the meafles in America, cotemporary with epidemic peftilence in Europe. In I7i2andi3, the plague was epidemic in Vienna, Hun- gary, Stiria and other eaftern countries. This difeafe was pre- ceded by the fpotted fever, which gradually changed to plague. At the fame time, whole countries were overrun with infeas. Short, vol. 2. 10. In England prevailed a fever which Mead has pronounced to have been of the fame kind, as the fweating ficknefs in the fix- teenth century.—He fays it was imported from Dunkirk, but how it came to be in Dunkirk, he does not inform us. During thefe calamities among men, the beaftsof the field did not efcape. A fatal diftemper among cattle broke out in 1711 and raged with fuch violence, in Italy, as almoft to deftroy the fpecies. It fpread for three or four years, and horfes perifhed by a fimilar peftilence. The writers who defcribe the difeafe, * Since the text was prepared for the prefs, I have found an accoUnt of a comet in 1712. My fufpicions therefore were well founded. 224 reprefent, it as a kind of plague ; and all agree that it fprung from a fingle infeaed cow from Dalmatia. How this cow be- came infeaed, they do not inform us. The truth is the difeafe was an epidemic, tho very infeaious ; and that it did not ne- ceffarily originate in infeaion, is proved by its appearing in many other parts of Europe. The difeafe began with rigors, which were followed by vio- lent fever, with eruptions like thofe of the fmall-pox, and ter- minated in five, fix or feven days. Baddam's Mem. vol. 6. 72. Lancifius p. 154. In 1714 began in Europe a feries of dry fummers. This year was rather fickly in England, and cattle alfo perifhed by an infeaious diftemper. In 1715 the fmall-pox and meafles were epidemic in England. In the fame year, Plymouth in Maffachufetts loft 40 of its in- habitants by a malignant difeafe, but no particulars are known. Hift. Col. vol. 4. 129. In 1716 the winter was exceffively fevere, and a" fair was held on the Thames. The rivers in Europe, even in Italy, were covered with ice. Short, vol. 2.17. In America, the 21 ft of Oaober O. S. was fo dark that peo- ple ufed lighted candles. Lima, the fame year, was fhaken by * an earthquake. Mem. Am. Aoad. vol. 1.144. Ulloa. Lima. In 1717 appeared a Comet, and there was an explofion of Vefuvius. Holland and Germany fuffered feverely the fame . year by inundations. In America the winter was terribly fe- vere, and remarkable for " prodigious ftorms of fnow," fays Mr. Winthrop of New-London in a letter to Dr. Mather, Hift. Col. vol. 2. 12. One hundred fheep belonging to that gentle- man were buried in the fnow on Fifher's Ifland, and 28 days af- ter, were dug out, when two of them were found alive ; and they both lived and thrived. The fnow was accumulated over them to the height of fixteen feet.—This fnow ftorm is diftin- guifhed in the Annals of America, as by far the greateft ever known. 225 This year was remarkable alfo in America for the death of many old people, fays Hutchinfon's Hift. vol.2. 223. In Europe catarrh was prevalent, and malignant fmall-pox among children. At Underwald in Switzerland prevailed a tertain, fo violent as to deftroy life at the fecond attack. The plague made its appearance in fome part of the Turkifh domin- ions. See Short, vol. a. 20, and Lady Montague's Letters. In 1718 the winter was cold in Europe, the feafon in Eng- land hot, and a comet was feen. The plague advanced. See Short, vol. 2. and Ruffel's Hift. Aleppo. In 1719 malignant fevers were prevalent in many parts of Eu- rope, marking a peftilential principle of great extent. The win- ter of 1719-20 in America was very cold. Douglasi In thefe laft years raged malignant pleurify in Hartford, in Conneaicut, with great mortality. In March 1719 an immenfe meteor paffed the heavens, illu- minating the earth and burfting with a tremendous report. Its diameter was calculated by Dr. Halley at a mile and a half. At this time the plague appeared in Aleppo, and carried off by report 80,000 people. Ruffel agrees that this difeafe came from the north, altho he has given us few particulars. It raged, as ufual, for two or three years. Hift. of Aleppo—pafllm. In 1718, 19, 20 and 21, fays Dr. Rogers, the greater num- ber of thofe who lived near the flaughter-houfes at Cork, died. In 1720 happened the laft great plague in Marfeilles, on which occafion has been publifhed " Traite de la pefte," a treatife in quarto, by Chicoyneau, under the fanaion of the French king, in which great efforts are made to prove the difeafe to have been imported from the Levant. The proofs of importation ftand thus. " Capt. Chataud left Said in Syria in January 1720, with a clean patent. The plague was not then in Said, tho it broke out foon after. On the paffage, feveral perfons died, and the phyficians at Leghorn, where the fhip flopped, pronounced their difeafe to be " a ma- lignant peftilential fever." 226 The fhip arrived at Marfeilles, and fome perfons who had concern with the goods, died in May. The fufpeaed goods were fubjeaed to fifteen days retreat and purification—they were forbid to be introduced into the city—the porters were ftiut up; but all regulations were fruitlefs. In June, deaths appeared in the city with diftinaive marks of the plague." On fuch flimfey evidence do the fticklers for the fole propa- gation of the plague by infeaion, ground all their affertions re£ peaing the difeafe at Marfeilles ! But it happens in this cafe, as in moft fimilar inftances, that the pretended proofs of infeaion carry refutation in the very face of them. In the firft place, it is an acknowledged faa, that at the time the fhip left Said, the plague had not appeared in that port, or town. It was at Aleppo and in other places far diftant in 1719, but had not broke out in Said. How, in the name of reafon, could men or goods be infeaed, when the difeafe did not exift in the place ? To overcome or rather to evade the force of this objeaion, the writers on the fubjea are compelled to refort to fuppofition. They fay it is poffible, the plague might have been in the place, tho not known or generally admitted. And here refts their whole argument! It is true, that fome of the feamen or paffengers died on the paffage, with a malignant peftilential fever. But in this cafe, the malady originated on board the fhip—and the infeaion is not traced to the Levant ports. .There is an end of the chain—the difeafe began without infeaion, on board the fhip, as malignant fevers have done in thoufands of other fhips. Again, it is admitted by Dr. Mead himfelf, p. 255, that from the time of the failors' death, after the fhip arrived, it was full fix weeks before the difeafe was known in the city of Mar- feilles ; a circumftance that renders it nearly impoflible that there could have been any propagation of the diftemper by infeaion. To remove this objeaion, the advocates of infeaion again refort to fuppnfiticn. They fuppofe it poffible fome latent feeds of the dihafe had been concealed in goods, or clothes—and fuch ridic- ulous fuggeftions are made the grounds of affertion. 227 But what completely refutes all thefe idle fuppofitions, is, that we have full evidence, that the plague in Marfeilles was generat- ed in the city, and gradually arofe from milder difeafes. In the beginning of the " Traite de la pefte," it is ftated from Mon. Didier and not denied, that " the preceding year 1719 was a barren year—the corn, the wine and the oil, were defec- tive. The heat of fpring was exceflive and followed by great rains, with wefterly winds-—the fruits were bad. In this year a peftilential fever appeared in Marfeilles, of which many died, and in fome, appeared buboes, carbuncles and paroitides." Here we obferve faas that always exift, before the plague, and which demonftrate the uniform operations of the laws of nature. The year 1718 began to exhibit malignant difeafes ia greater numbers than ufual. In 1719 the plague broke out at Aleppo, and in the north and weft of Europe, malignant fevers became in many places, epidemic and peftilential. In 1720, the peftilential ftate of the air, arrived at its crifis in Marfeilles. The peftilence in Europe exhibited a regular progrefs, from or- dinary typhus fever to the plague. A fatal fmall-pox and fpot- ted fever prevailed in Piemont. To demonftrate this faa, the reader will only turn to the bills of mortality in London, Amfterdam, Vienna, Drefden, &c. for the years under confideration, and obferve every where the effeas of a general unhealthy ftate of air, in the increafe of the number of deaths.—The bills of mortality in Bofton and Phila- delphia alfo prove this ftate of air to have extended to this coun- try ; and the malignancy of it feems to have abated in America after 1721, in which year the fmall-pox was very mortal in Bofton. The accounts of difeafes in America, at this period, are few and imperfea. Tradition has preferved the memory of defola- ting ficknefs, at various times and in various places, fome of which, I fufpea, refer to this period, but I am not able to af- certain the dates, with any certainty.* By accident however, • My father mentions an inftance, which he believes to have wen not long before his birth, which was in 1722. An aged lady of 96, who was born in 1702, informs me that a malignant pleurify raged when fho was 17 yean old ; this fixes the period in 1719. 228 I am able to determin pofitively the peftilential ftate of air in America in 1720. A genuine letter is extant, from Thomas Hacket of Duck Creek, now in the ftate of Delaware, dated April 10th 1720, in which he ftates that a mortality prevailed in that place, which exceeded that in London in 1665, and al- moft depopulated the village. I have feen the letter in poffeffion of Dr. Rufh. Ih 1721 there was an eruption of a volcano in Iceland. A dreadful dyfentery raged in Upper Saxony. In 17 20 there was a great earthquake in China, and in 1721 fhocks were felt in the Mediterranean, by Dr. Shaw who was then on his travels to the eaft.—In Oaober 1720, fire arofe out of the fea near Tercera, one of the Azores, and a fmall ifland arofe, Buffon's Nat. Hift. In 1722, the feafons were cold, wet and rainy. In Auguft happened a moft violent ftorm in Jamaica and S. Carolina. In May an earthquake in Chili. The winter of 1722-3 was cold and dry in England. In 1723 appeared a comet, and on the 24th of February, O. S. a mighty tempeft which is recorded among the memorabilia of America. The wind blew violently from the fouthward, then veered fuddenly to the eaftward and northward, bringing in a tide which rofe two or three feet above the Long Wharf in Bofton, and flowed over all the lower part of the town, filling cellars and deftroying property to a great amount. Immenfe damage was fuftained in all the maritime towns. See Mather's letter. Hift. Col. vol. 2. 11. The confluent fmall-pox raged in England See the London bill of mortality for 1723. Dyfenteries, pleurifies and other inflammatory complaints prevailed in the different feafons. The bilious plague prevailed in Barbadoes, faid to be import- ed from Martinico. We are not informed from whence it came into Martinico. In thefe accounts of infeaions, we are not led to the end of the chain. Tn the fame year 1723 prevailed in many parts of the colony of Rhode-Ifland, a fatal difeafe called the " burning ague." It was particularly fatal, near Providence, between Pautucket 229 and Pautuxet. In proportion to its patients, no difeafe in A- raetica, was ever more mortal. It did not prevail in a large town, but in villages, and perhaps the clearing of fome neigh- boring fwarnps might have been one caufe of the difeafe. The year however was lefs healthy than ufual. A difeafe of the fame name is noted once or twice in ancient hiftory. See the year iooi. The year 1724 in England was moftly wet and cold ; the whooping cough prevailed ; but the year was generally healthy. The fummer of 1725 was alfo wet and cold in England. In January a fevere froft produced many inflammatory complaints. In this year happened violent earthquakes in South-Amer- ica, and eruptions from two volcanic mountains in Iceland. I have no account of the weather and difeafes in America. I only learn from an old gentleman, that one of the winters be- tween 1722 and 1725 was called, " the hard winter." The winter of 1726-7 was changeable in England, but moftly cold with great fnows. Remitting fevers prevailed in fummer and inflammatory, in winter, which fwelled the bills of mortal- ity to an unufual degree. At the fame time the plague raged in Egypt. The fame winter in America was milder than ufual—the fum- mer of 1727 was very hot and dry. See Dudley's account of the great earthquake. Philof. Tranf. and Mufeum, vol. 5. 363. In 1727 appeared a comet—an explofion of fire took place from Vefuvius and a volcano in Iceland. The interior counties of England were fhaken by an earthquake ; and on the 29th of Oaober of the fame year happened one of the moft extenfive and violent earthquakes ever known in America. A malignant dyfentery was epidemic in Bern. In America, the fummer was very hot. Short, vol. 2. VanTroil on Iceland. Williams on Earthquakes. Memoirs of American Academy. Pennant's Arctic Zoology. Zimmerman on dyfentery. Phil. Tranf. 437. Baddam's Mem. vol. 10. no. This was a fickly year ; fee the bills of mortality for London and Amfterdam, Bofton, Philadelphia Chrift's Church and Dub- lin. The prevalent difeafes in London were fevers of a malig- 23° nant type. What the difeafe was in Philadelphia, I know not; but the greateft mortality was in February, March and April. In 1728 putrid fevers were frequent—the fummer was cold in England and the following winter fevere. The year 1727 was unproduaive ; corn in England was fcarce and the fcarcity continued into this year. An eruption of a volcano in Icelaed and the plague in Egypt marked this year, 1728. The eruption in Iceland continued till 1730. This year, 1728, the fummer weather in South-Carolina was ttnufualfy hot and dry. The earth was parched and the fprings exhaufted. In Auguft a violent hurricane occafioned an inun- dation, which fpread over the low grounds and did incredible damage to the wharves, houfes and corn fields. The ftreets of Charleftown were covered with boats; the inhabitants were driven to the upper ftories of their houfes; twenty-three fhips were driven afhore and thoufands of trees were levelled. The fame feafon, the bilious plague raged in Charlefton with great mortality. Hift. of S. Carolina, vol. 1. 316. In 1729 appeared a comet, and in autumn a univerfal catarrh to Europe, and perhaps over the globe. This was preceded by meafles. It feized with a flight chill, a flow fever, weari- nefs, continual hoarfenefs, pain of the head, and difficulty of breathing. The fuddennefs of the attack was aftonifhing, and it proved fatal to many aged and phlegmatic people. Many pleurifies and peripneumonies followed. Its firft appearance was in Poland, Auftria and Silefia, and it marched over Europe in five months. At the clofe of this epidemic in 1730, Vefuvius difcharged its contents of fire. In this year 1729 the plague was in Aleppo, and it will be feen that the bills of mortality in the north of Europe exhibit a fickly ftate, through a period of many years at this time. The meafles prevailed in America, and in Farmington, Conneaicut, a malignant pleurify. The fummer of 1729 was in moft parts of England, very wet, in other parts, dry; but this made no difference in the prevalence of the catarrh. The fmall-pox was very frequent in England. 23I This year alfo is remarkable for the firft appearance of the yellow fever or black vomit at Carthagena, in South-America, where it made dreadful havoc among the crews of the fleet un- der Don Domingo Juftiniani. The fame fate attended the crews of the galleons under Lopez Pintado in 1730. Ulloa, vol. 1. p. 44.—Lond. 3772. The winter of 1729-30 was very mild in Europe. There was a fmall eruption of Vefuvius in 1730 and in Iceland, and an earthquake in South-America, on the 8th of July totally de- molifhed the towns of Conception and Santiago, in Chili. This dreadful calamity was foon followed by an epidemic difeafe which fwept away greater numbers than the earthquake. Ulloa, vol. 2. 23s, 257. The plague was in Cyprus about this time, and was preceded by an earthquake. In January 1729, the rivers and canals in Holland were cov- ered with ice, from 12 to 20 inches thick. Meafles and angi- nas prevailed, and in autumn the fmall-pox made great havoc. Bad. Mem. vol. 9. 3i4andfequel. It will be obferved that thefe eruptive difeafes in Holland were cotemporary with the meafles in America, and the malig- nant pleurify in winter, which was the predominant fymptom of a peftilential conftitution of air, in America, until the year 1761. The winter of 1730-31 was very fevere in Europe. It appears from the bills of mortality in Bofton and Philadel- phia, that the years 1730 and 31 were fickly. What the mal- ady was which fwelled the mortality in Chrift Church to double the ufual number in 1731, I am not informed ; but the greateft mortality happened in March and April. The fmall-pox was the difeafe which augmented the bill in Bofton in 1730. In 1731 the fmall-pox fpread in New-York, and occafioned an adjournment of the legiflature in September. Journals, vol. 1. p. 633. In 1732 appeared a comet, and in America the following winter was very fevere, continuing from the middle of Novem- ber to the end of March. In Europe, the winter was mild. Douglas Sum. Short on Air." Lima in South-America was fhaken, this year, by an ' earth. 232 quake ; a fhock was experienced alfo in England ; and in No- vember the fame was experienced in Canada and New-England. On the 9th of Auguft happened a remarkably dark day. See Douglas, and Profeffor Williams Mem. Am. Acad. In this year, the plague prevailed at Tripoli, Sidon and Da- raafcus; and the American plague at Charlefton, S. Carolina. Lining's letter. Edin. EiTays, vol. 2. Towards the clofe of the year, in Oaober, commenced in America a fevere univerfal catarrh, which appeared in Europe alfo in December. It fpread over all Europe, in the beginning of 1735, and probably over the earth, as it was experienced at the ifle of Bourbon, in the Indian Ocean. Mem. of Dr. Hunt of Northampton, and the Medical pub- lications in Edinburgh. This epidemic feems to have been the precurfor of the moft peftilential period of this century. The fummer of 1733, in England, was dry and pleafant. The winter following was very mild. The plague raged at Aleppo. The fcarlatina appeared in Edinburgh ; and the chin cough alio began in England in 1734, continuing to prevail in 1735. This period alfo was noted for meteors. In June 1734, a ball of fire paffed through two oppofite windows of a fteeple at Air, in Scotland, broke one end of the bell-joift, and defcended to the earth, without doing further harm. A boy in the neigh- borhood was killed by another ball of fire. Sinclair's Stat. Ac. of Scotland, vol. 1. 96. On the 2d of February 1735, Popayan in S. America, was nearly ruined by an earthquake. The fummer of 1735, was very wet and cold. In Europe in 1734 commenced a flow putrid fever. An anginous fever be- came epidemic among children, and quinfies or fwellings of the throat, with contagion, and great mortality. Small-pox of a malignant kind prevailed at the clofe of the year. The peftilen- tial ftate of the air is faid to have affeaed birds, which died in the cages. Canine madnefs prevailed. Short, vol. 2. Van Swieten, vol. 16. p. 56. In I735» prevailed a fpotted fever of a faial kind, and other 233 malignant diforders, with hydrophobia. In Scotland, the me* lies became epidemic, and fevers of a bad kind. Effays and Obf. Edin. Phil. Tranfac. vol. 4, Huxham, vol. 1. Earthquakes were felt in England in 1734 and 1736. In 1736 and 7 a fatal ulcerous fore throat and malignant perip* neumonies, prevailed in France. In 1735 or 6, three or four thoufand people, in the Orkney Iflands, perifhed with famin. The fcarcity there in 1782 and 3 was alfo deplorable, but none perifhed. Sinclair'9 Scotland, vol. 7.497. While thefe epidemics were prevailing in Europe, America felt the peftilential ftate of air. In May 1735, in a wet cold feafon, appeared at Kingfton, an inland town in New-Hamp- fliire, fituated in a low plain, a difeafe among children, commonly called the " throat diftemper," of a moft malignant kind, and by far the moft fatal ever known in this country. Its fymptoms generally were, a fwelled throat, with white or afh-colored fpecks, an efflorefcence on the fkin, great debility of the whole fyftem, and a tendency to putridity, It firft feized a child, who died in three days. In about a week afterwards, three children, in another family, at a diftance of four miles, were fucceflively feized and all died on the third day. It continued to fpread, and of the firft forty patients, not one recovered. In Auguft, it appeared at Exeter, a town fix miles diftant. In September, it broke out in Bofton, fifty miles diftant; altho* it did not appear in Chefter fix miles weft of Kingfton, till Oao. ber.—It continued its ravages, through that year into the next, and gradually travelled fouthward, almoft ftripping the country of children. Very few children efcaped, for altho' the difeafe was very infeaious, yet its propagation depended very little on that circumftance. It attacked the young in the moft fequefter- ed fituations, and without a poffible communication with the fick. It was literally the plague among children. Many families loft three and four children—many loft all. In fome places, this diftemper was more fatal than in others-* Ff 434 cotmtry towns fuffered more than populous cities. And it fhould be here remarked, that the virulence of this fpecies of difeafe feems at times to be greatly augmented by cold and wet weather —it is moft mild in cities where the air is, in a degree, correc- ted of its rigor and moifture.—To this obfervation however there are exceptions. Scorbutic people and thofe who lived on# pork, and of courfe the poor, fuffered moft. In fome families, it was comparatively mild—in others it was malignant like a plague. This difeafe gradually travelled weftward and was two years in reaching the river Hudfon, diftant from Kingfton, where it firft appeared, a- bout 200 miles in a ftrait line. It continued its progrefs weft- ward, with fome interruptions, until it fpread over the colonies. Few adults were affeaed ; its principal ravages were among per- fons under age, or rather Under puberty. For many years after it was epidemic, it frequently broke out in different places with- out any apparent caufe, but did not fpread—a ftriking proof that fuch difeafes will not become epidemic by the fole power of in- feaion, but that fome general caufe muft aid its propagation, or it will perifh in its cradle. This is probably true of every fpecies of peftilential difeafe. From an elderly lady of great Gbfervation in New-Haven, I have learnt that perfons who, recovered of this diftemper, were fubjea, all their lives, to fore throat and quinfies, and what is perhaps more remarkable, that few or none of them have lived to be old. It is at leaft apparent, in the fphere of her obferva- tion, that thofe perfons have died at an earlier age than others. Thefe faas are ftriking proofs how much the whole fyftem, and efpecially the feat of the difeafe, was impaired in ftrength and firmnefs, by that diftreffing malady. A gentleman ftill living, who was affeaed with the fame difeafe in 1742, informs me that his conftitution has never recovered from the fhock it received from that malady. The invafion of this diftemper was gradual, and for fome time before its attack, children appeared to languifh. It was not always attended with great proftration of ftrength, for per- *35 fans were often walking, an hour or two before their deatk* The fame happened in the angina of 1794. See further particulars in Colden's account. Medical Okfer. and Enq. London, vol. 1. an, and in Belknap's Hifto- ry New-Hampfhire, vol. 2. 118. Difeafes among cattle in New-Hampfhire marked this period. In 1736, and during the rage of the ulcerous fore throat ia America and in England, the plague made terrible havoc in E- gypt—authors relate that Cairo loft 10,000 perfons in a day.-— . In Nimeguen raged a malignant dyfentery. In 1737 while the angina maligna was fpreading over the northern parts of America, the bilious plague prevailed in Vir- ginia. In England and Scotland, the meafles broke out and prevailed in 1735 and 6, cotemporary with the angina in Amer- ica. Dr. Short relates thac the firft perfon feized was a woman in her child-bed illnefs. At the fame time prevailed miliary fevers in Cornwall, ac- companied with glandular fweftings. Coughs, deflexions and catarrhs were frequent. A peftilential difeafe in Devonfhire fwept away cattle and fwine. In 1737 a very fevere influenza invaded both hemifpheres. It commenced in November. In 1737 alfo appeared a comet; Conftantinople was fhaken and Smyrna half deftroyed by an earthquake. A fmall fhock was felt in Bofton. In Oaober of this year, a ftorm or hurri- cane in the Eaft-Indies, deftroyed 20,000 veffels of different fizes, and 300,000 people. There was a great eruption ©f Ve- fuvius in the fame year. In Iceland alfo was an eruption be- tween 1730 and 1740, but the year is not fpecified. See Gent. Mag. and Tablet of Memory, art. Storms. A moft fingular meteor in the fame year, followed by a very fevere winter. This peftilential conftitution did not produce the fame difeafes in England, as in France and America. The fatal ulcerous fore throat was cotemporary in America and in France in 1737 ; but that difeafe did not appear, in its formidable array, in Eng- land until 1742. In 1734-5 appeared its filter-malady, the fcarlet fever in Edinburg ; but it fubfided; and the epidemic S3* took the form of meafles of a bad type, with hoarfehefsj defluxions and catarrh. The catarrh prevailed alfo in Barbadoes in the clofe of this year and beginning of the next, and in New- England was a great death of fifh and water fowl. In 1738 fudden deaths, vertigoes and apoplexies followed the preceding epidemics in England. The plague raged at Ockza- kow, at Barbadoes, and in New-Spain the peftilence was fo gen- eral and mortal, as to threaten the country with depopulation. In 1739 the fmall-pox prevailed in New-York, and fome dyfenteries, but I hear of no remarkable occurrences in this year ; except that angina maligna appeared in England in a few fporadic cafes, but did not fpread at that time ; and an infea- ious fever prevailed at Charlefton. Journals N. York AiTembly, vol. 1. 756. Fothergill's ac. Sore Throat. A comet was feen in 1739, and the winter following in Eu- rope was the fevereft known fince 1716 or perhaps fince 1709. The cold continued till June and was fucceeded by a dry feafon ; then a wet, cold autumn. A dearth fucceeded in Scotland, and meafles fpread over America. In England fpread the whooping cough in December 1740. The fmall-pox prevailed and in 1741 that difeafe, with the fpot- ted fever were very mortal. See the London bills of mortality. In Briftol and Galway, in Ireland, the fevers fell little fhort of the plague. Huxham, vol. 2. Short, vol. 2. It was computed that in 1740 and 41, Ireland loft 80,000 people by famin, dyfentery and fpotted fever. Rogers on Epid. Amfterdam experienced the fame peftilential conftitution. See the bills. Not lefs remarkable were the feafons in America. In 1740- 41, a year later than in Europe, the winter was of the fevereft kind. Many cattle perifhed for want of food. Journals of N. York AiTembly, voL 1. 799, 804. During this winter meafles prevailed in Conneaicut. The American plague appeared in Philadelphia and Virginia. Ia Scotland many periflied by famin. Sinclair's Scot, vol 6. 433, ^37 Don Ulloa relates an opinion among the Spaniards in South- America, that in 1740, the black vomit was firft introduced into Guayaquil by the galleons from the fouth feas. They aver the difeafe not to have been known there, anterior to that year, It was moft fatal to feamen and foreigners, but the natives did not efcape. Here we have a new fource of yellow fever ! • In 1742 the ulcerous fore throat of a malignant kind appear- ed in England, and continued to prevail more or lefs for many years, and in 1745 became very infeaious. See Short, vol. 2. and Fothergill's Works. The fummer of 1742 in England was dry. In America, the fame angina prevailed in 1742. From 1740 to 1744 peftilential difeafes prevailed in all parts of the known world. In Syria, the winter of 1741-2 was very fevere. In March began an acute fever in Aleppo, attended with a fevere pain in the right hypochondrium. The plague had previoufly fhown it- felf on the fea coaft. In April, fays Alex. Ruffel, fome reapers brought the infeaion into the neighbourhood of Aleppo. In the city, no notice was given of the plague, till the 18th of May ; but on ftria enquiry, it was found that cafes had occur- red before that time. Whether the " reapers" introduced the fomites into the city, the author does not inform us. The diftemper made no great havoc in this feafon. It abated in July, and nothing is faid about infeffion, till November, when a few more cafes occurred. In February 1743 a few cafes ap- peared and in March an alarm was given. It was more general in this year, but difappeared in 1744. When the difeafe fubfided in Aleppo, it was followed by di- arrheas and dyfenteries with petechia: ; and fome obftinate in- termittents. In December 1742 and January 1743 were earthquakes with great fnows, violent rains and froft. In 1742 a mortal fever prevailed at Hollifton in Maffachu- fetts, in which died Mr. Stone, the minifter and fourteen of his -congregation. In this year was feen a comet. In the fpring of 1743 j a fmart fhock of earthquake convul- 23a fed Sicily, Naples and Malta. A catarrh prevailed at the fame time. Thefe were the precurfors of the dreadful plague which raged, in the following fummer, at Calabria, Reggio, and ef- pecially at Meflina in Sicily, where perifhed 46,000 inhabitants oat of 72,000. The fummer was violendy hot, and dyfentery prevailed in other parts of Italy. At the fame time, New-York was feverely affliaed by the bil- ious plague, where died, in one feafon, 217 of the inhabitants —a confiderable number for the population of that day.* I know not what difeafes prevailed in Bofton, but the bill for that year fhows it to have been fickly. The year 1743 was diftinguifhed for a tremendous eruption of fire at Cotopaxi, a mountain in the province of Quito, five leagues north of Latacunga ; all the neighboring villages were ruined by floods from the melted fnows of the mountain. The eruption was repeated in 1744. Ulloa, vol. r. Venice fuffered by an inundation in 1743, an<^ tne vear was remarkable for violent ftorms, at Bofton, Jamaica, and in many countries. In December 1743 appeared a comet of diftinguifhed magni- tude, which was vifible till February of the following year. This was probably the fame which appeared in 1401, and in both inftances attended with peftilence. In 1744 fevere catarrh fpread over Europe. It was at Rome in February ; at London in March; and in a few weeks per- vaded England. * " New-York, Oct. 14, 1743. By the Mayor of the City. An account of perfons buried in the city of New-York, From July 25th to Sept. 25, 1743. From Sept. 25 to Oct. 23d. Children, 51 Children, 16 Grown perfons, 114 Grown perfons, 36, 165 217 And I do find by the beft information I have of the doctors, &c. of this city that the late diftemper is now over. JOHN CRUGER, Mayor." New-York at that time contained about 7 or 8000 inhabitants. 239 In Jane of this year, was an earthquake of confiderable vio- lence in New-England. In 1745 Lima was fhaken by an earthquake. An infeaious fever broke out among the troops employed in the expedition to Louifbourg. A fimilar fever prevailed at Bofton ; and how far the health of the town was affeaed by the returning troops, I am not informed. This was a time of general ficknefs. In Charlefton prevailed the infeaious yellow fever, while Egypt and Smyrna were fuffering the ravages of the plague. The bilious plague prevailed, at the fame time, in New-York. In this year, the town of Stamford in Conneaicut was fe« verely diftreffed by a malignant dyfentery, which fwept away feventy inhabitants out of a few hundreds. The difeafe was confined to one ftreet. The year 1746 was probably ftill more unhealthy. An earth- quake laid Lima and Calao in ruins. The concuflion began on the 28th of Oaober, about fix hours before the full of the moon ; and at intervals, the fhocks were repeated for four months, in which time they amounted to four hundred and fifty. During thefe convulfions, fire burft forth in feveral places of the diftant mountains. Many days before the fhocks began, hollow rumbling noifes were heard in the earth, at times refembling the difcharge of artillery. Similar founds continued for fome time after the earthquake. See the melaachely tale in Ulloa, vol. 2. 83. Albany was, in this year, vifited by a malignant difeafe called by Colden, a nervous fever ; and by Douglas, the yellow fever. From an old citizen, who was living in 1797, my friend Dn. Mitchell obtained the following particulars relative to that difeafe. The bodies of fome of the patients were yellow—the crifis of the difeafe was the ninth day ; if the patient furvived that day, he had a good chance for recovery. The difeafe left many in a ftate of imbecility of mind, approaching to childifhnefs or idio- cy ; others were afterwards troubled with fwelled legs. The difeafe began in Auguft, ended with froft, and carried off forty-five inhabitants moftly men of nabuft bodies. It was faid to be imported. 240 As this was an unufual difeafe in Albany, ingenuity was occu- pied to find out its origin. It was reported that a like difeafe pre- vailed in New-York, and that it had been imported in a veffel from Ireland. Nervous, yellow fever imported from Ireland! Such are the vulgar tales that difgrace this age of fcience and philofophy. From what fairy land were imported the malignant difeafes, which every where fwelled the bills of mortality in the feme year ?—Not that I would infinuate that difeafes of a certain kind are nbt infeaious. A peftilential fever originated in the Chebuao fleet, under the Duke D'Anville, which landed an ar- my on our fhores in this fame year, and one third of the Indians who vifited the cantonments, died. .There the difeafe fubfided, without becoming epidemic. But what I feverely reprobate is, the difpofition of men to trace all the evils of life to a foreign fource ; when the fburces are in their own country, their own houfes, and their own bo- foms. A fimilar difeafe raged, the fame year, among the Mohegan Indians. See the poftfcript at the end of the volume. At Zurich in Switzerland and in Saxony prevailed a very ma- lignant dyfentery. Indeed for a number of years, at this peri- od, dyfentery was epidemic in many parts of Europe and A- merica. In 1747 prevailed epidemic catarrh in America and Europe. In the fame year the bilious plague prevailed in Philadelphia.—In 1748, in Charlefton. The fame years were fickly in Bofton. In 1747 appeared a comet, and Etna, which had been quiet more than forty years, commenced her difcharges of fire and lava. In the Weft-Indies, a tremendous hurricane laid wafte the Iflands. Two comets appeared in 1748 ; the winter was fevere, and two or three exceffively hot and dry fummer6 fucceeded. In England the fummer of 1747 was very dry. In 1748 a faft was appointed in Maffachufetts on account of the drouth. In England the angina maligna continued its ravages with in- creafed mortality. The fame malady prevailed in France in 1749, and there was an earthquake at London. The 18th of 241 June was a noted hot day, and Mars was as near to the earth as her orbit will permit. Almanack for 1749. In 1749 the dyfentery and nervous long fever vifited many towns in Conneaicut with diftreffing mortality. Waterbury fuf- tained a lofs of about 130 of her inhabitants principally by dyfen- tery. Cornwall, then a new fettled village, on high mountains, loft twenty of her citizens. Hartford was feverely vifited with in- termittents, for the laft time. The fummer was very dry, and locufts or grafs-hoppers overrun the fields and devoured the her- bage. Douglas, vol. 2. 208' I am authorized to fay that the terrible dyfentery in Woodbu- ry did not appear to be very contagious—it excited great alarm ; every one avoided the fick, if poffible ; but many who lived re- mote and never came near the fick, were feized, and fuddenly died.f In 1749 and 50 the dyfentery, according to Zimmerman, made great havoc in the Canton of Berne. It is remarkable that this formidable difeafe fhould be thus prevalent in both hemifpheres at the fame time, and for a feries of years. About this time meafles prevailed in America. In 1750 appeared a comet, and the fummer was exceffively hot. In Philadelphia, the heat raifed the mercury to 100 deg. by Farenheit. The plague carried off 30,000 people in Fez, and one third of the inhabitants of Tangiers. Violent tempefts marked this year, in America, and an unu- fual fwell of the Severn in England. Earthquakes happened in England, Jamaica, Peru, Leghorn, Rome, Sicily and Lapland. At Bcauvais, 50 miles from Paris, broke out a peftilential dif- eafe, called la Suete, refembling the fweating ficknefs, termina- ting fatally in three days. See Gent. Magazine. At Bethlem in Conneaicut raged a mortal fever, which fwept away between thirty and forty of the inhabitants. The exci- ting caufe was fuppofed to be the exhalations from a fwamp which f M- S. letter from Z. Beers. 242 had been drained. It is not improbable that this might have aid- ed the general principles of difeafe. Med. Repof. vol. i. p. 523. The winter of 1750-51 is mentioned as extremely fevere in 'America. Vefuvius difcharged fire and lava, in 1751, and on the 7th of March, a moft dreadful tempeft at Nantz in France, deftroyed 66 fhips, with 800 lives. On the fame day, a tempeft at Jamaica did damage to the amount of a million of dollars. A ftorm at Cadiz on the 8th of December deftroyed 100 fail of fhipping. On the Adriatic coaft was an earthquake. In this year Conftantinople loft 209,000 inhabitants by the plague.—The preceding winter was cold in Turkey, and the old people prediaed a fevere plague from the quantity of fnow that fell in Conftantinople. This prediaion was founded on long obfervation ; and I am able to confiim the juftnef. of it, by difcovering that thofe years which produce the moft violent ac- tion or difcharges of elearical fire, generate moft fnow, hail and cold. Chcnier's Morocco vol. 2. 275. In America the fpring flights of pigeons were unufually large. The dyfemery was epidemic and mortal, in the fame year, at Hartford and New-Haven ; probably in many other places.— With this fatal dyfentery prevailed a mortal angina for feveral years. The fame concurrence of thefe difeafes will be mention- / ed under the year 1775. In England, the 'fummer of 1751 was cold and wet ; and a mortal diftemper prevailed among horfes and cattle, in moft parts of the coantry. In Chefhire died 30,000 cows. In Glafgow the feafons were very fickly. Gent. Magazine. Great and uncommon inundations occurred in the fame year, in France, England and Scotland. In Cork the water was three feet deep in the midft of the city. The dyfentery and ulcerous fore throat were very fatal, this year in Guilford. In 1752 the fummer in South-Carolina, and probably in all parts of America, was diftinguifhed for intenfe heat. The ther- mometer, for nearly twenty days fucceflively, varied between *43 go and 101.—The effeas of this heat were vifible in a number of fudden deaths by apoplexies. There were fome cafes of bad fever, but no epidemic. In September a violent tempeft laid the city under water. The dyfentery was ftill prevalent in thenorth- ern parts of America. Mufeum, vol. 3. 316 andfequel, Dr. Chalmers. In Ireland prevailed angina of fuch a malignant type, as to kill the patient fometimes in eight or ten hours. See Rutty on weather. The plague raged in the Eaft. An. Reg. 1766. 100. In this year Adrianople was nearly deftroyed by an earthquake. In Hinfdale, on Conneaicut river, in the ftate of New-Hamp- fhire, was aH eruption of fire from a volcanic mountain, called weft river mountain. Mem. Am. Acad. vol. 1. 316. In America the winter of 1752-3 was long and fevere. I have no account of any general epidemic in 1753 ; but particular places were vifited with diftreffing ficknefs. A fingu- lar inftance of a local peftilence occafioned by vapor deferves to be related. In autumn 1753 &fter ach*y f€af°n> arofe in Rouen, the chief city of Normandy, a thick fog, with the fmell of fulphur, which increafed to that degree, that in the evening, lights could not be diftinguifhed at any confiderable diftance. It did not wholly difappear, till the next day. It was more denfe in fome ftreets than in others. In three or four days after, began an epidemic ficknefs which feized both fexes, with chills, laffitude, lofs of appetite, flight pains in the arms and legs. Thefe fymptoms were followed by bilious loofenefs, naufea and vomitings. Moft patients bled at the nofe, frequently in fmall quantity. The head ache then be- came violent, with a fmall, hard pulfe—a high fever followed. The region of the ftomach and hypochondria was tumefied; this fymptom was fucceeded by a tenfion of the belly—and a flight delirium followed. The tongue was Ijrown or black, but moift ; fometimes with green ulcers or apthas. The patient died the 5th, 7th, or i ith day; but not in every cafe. Some were 544_ thirty, or forty days in recovery ; many were left with a puflt- nefs of the faee, hands and legs. In fome other parts of France appeared peripneumony and in- flammation of the pericordium, which was called a new difeafe. Phil. Tranf. vol. 49. In December 1753 anc* January fucceeding, the fmall town of Hollifton, in Maffachufetts, loft forty-three of its citizens, by a fever. The difeafe began with a violent pain in the breaft, or fide, not often in the head ; then fucceeded a high fever, but without delirium. The critical days were the 3d, 4th, 5th, or 6th. Some of the patients appeared to be ftrangled t© death.. The town contained no more than 80 families. Hift. Collections, vol. 3. 19. The winter of 1753-4 in Europe was very cold. In 1754 was a great eruption of Vefuvius which lafted feveral weeks, and violent earthquakes in England, Conftantinople, and Amboyna, in the Eaftern Ocean. The heavens appeared to be in a flame, and Egypt, which rarely feels earthquakes, was feverely fhaken, and 40,000 of the inhabitants of Cairo, perifhed in the ruins of two thirds of the city. The gangrenous fore throat was very mortal in Ireland, and prevalent in England. See Rutty on weather. The fame fpe- cies of angina was, at the fame time, very fatal in America. See Belknap's Hift. N. Hampfliire, vol. 2. 121. In Maryland, the earth was deluged with exceflive rains, and intermittents were unufually obftinate. Gent. Mag. 175?. At this time there were two or three very* mild winters in America. In 1754-5 and 1755-6 floops failed from New- York for Albany in January and February. Smith's Hift. N. York, 82. In this inftance, America is an exception to the general rule, that fevere winters extend over both hemifpheres, about the time of great volcanic eruptions. The feverity was limited to the other continent. The year 1755 .was remarkable for violent earthquakes, and volcanic eruptions from Etna and the mountains in Iceland. In April, Quito in South-America was demolifhed. Portugal had fuffered for three or four years, moft exceflive 245 drouth, by which all fprings were exhaufted. But the year >755 was rainy. On the firft of November, a tremendous con- vulfion laid Lifbon in ruins, with the deftrudrion of 50,000 lives. This fhock was felt on the whole Spanifh coaft, and 10,000 people periflied on one of the Azores. In Mitelene, an ifland in the Archipelago, 2000 houfes were deftroyed. The day preceding this concuflion was remarkable for a haze or vapor that obfcured the fun. On the 18th of November, America fuftained a violent and extenfive fhock ; but its effeas were not very calamitous. The fifh in the ocean did not efcape without injury. Two or three whales, and multitudes of cod were feen, a few days after, floating on the furface ©f the water. In the remarkable year 1755, the moft prevalent epidemics feem to have been angina maligna, and catarrh, which fpread over France and England. The angina maligna was very mor- tal in fome parts of America. In one town on Long-Iflaad, two children only, under twelve years of age, furvived. M. S. of Mr. Reeve. In this year alfo prevailed a petechial fever in Ireland, and according to Baron de Tott, Conftantinople loft 150,000 in- habitants by the plague. See his.Memoirs, Fothergill on fore throat and Raitty on weather. The winter of 1756-7 in Syria was exceffively fevere ; the fruits were deftroyed, olive-trees, which had withftood the weath- er for fifty years, were killed, and thoufands of poor people per- ifhed with cold. Lon. Mag. 1764. In the following fummer, crops failed, a dearth enfued, and fo fevere a famin that parents devoured their own children ; the poor from the mountains offered their wives for fale in market, to procure food. Ibim. This winter was alfo very fevere in Europe. In 1756 ap- peared a comet and there was an eruption in Iceland. A mete- or was feen in France, and earthquakes were experienced in va- rious places. »4& In 1756-57 the catarrh was very prevalent in America, fol- lowed by an earthquake in July. This catarrh preceded the lame eipidemic in Europe by one year. In 1758 catarrh fpread over Europe, and the plague began to fliow itfelf in Egypt and Smyrna. In November, a large meteor was feen in Great-Britain, and is defcribed by Sir John Pringle -in the Philofophical Traafaaions.* In this year alfo, the pe- techial fever, the precurfor of the plague, began to fhow itfelf, in Aleppo.—The fummer in America was extremely hot. Letter of Gov. Ellis, Mufeum, vol.5. 151. In 1759 appeared two or three comets; and in November a moft tremendous eruption of Vefuvius. In Auguft was an earthquake at Bourdeaux—and one at Bruffels. The winter following 1759 was exceffively cold in both hemifpheres. In Leipfic, centinels froze to death ; and in South-Carolina, the fnow covered the earth to the depth of nearly two feet. In England, the cold was lefs fevere. The year 1759 was memorable for violent earthquakes, in Syria. Buildings were demolifhed and Damafcus was buried in ruins. The fhocks were repeated for many weeks. In Novem- ber, Truxilloin Peru was fwallowed up by means of an earth- quake. It will be obferved that this happened in the month, when Vefuvws was in eruption. Thefe great phenomena an- nounced a general and fevere peftilence, arid the effeas of the general principles of difeafe were foon felt over Europe, Afia and America. Annual Regifter, 1761. 96 and paffim. The earthquakes in Syria were preceded by drouth and followed by exceflive rains. See Ruflel on the plague at Aleppo and Velney's Travels. In 1759 the plague began to appear in Cyprus, and at Acre and Latakia on the Syrian coaft. In Copenhagen raged fmall- pox with great mortality. In New-England were fhocks of earthquake in February, at Bofton and Portfmouth. An. Regif. 1759. 88. In Au- tumn an unufual tempeft and tide at Nova Scotia. * Seen from Dublin, it moved from fouth to north, Annual regifter, J759- J8. 247 In America, cotemporary with the commencement of the plague in Egypt, appeared the meafles, in 1758, and the year 1759 appears, hy the American bills of mortality, to have been very unhealthy. The predominant difeafes were the meafles aad dyfentery. M. S. letter from Dr. Betts of Norwalk. The meafles appeared in 1758, but was moft extenfive in 1759. This is an inftance of the prevalence of dyfentery and meafles in the fame year. In this year alfo the fcurvy, an endemical difeafe in Canada, was unufually mortal. Lind, p. 26. At Bombay, a meteor of extraordinary brightnefs was feen on the 4th of April, 1759. After the fevere winter of 1759-60, happened in America, a fnow ftorm on the 3d of May, when the apple-trees were in bloffom. The difpofition of the elements to generate fnow and hail, during peftilential periods, has already been remarked. M. S. of Mr. Whitman. The fpring of 1760 in America was very dry. In 1760 earthquakes were repeated in Syria, and the plague appeared at Aleppo, Jerufalem and Damafcus. It continued to ' extend and increafe, until the fummer of 1762 ; after which it declined. In Holland and Belgium were fmall fhocks of earth- quake—preceded by flafhes of light. Annual Regifter 1760. 70. Ruffel on the plague at Aleppo. Indeed earthquakes were felt in moft parts of Europe. Cyprus, which had been free from peftilence for 30 years pre- ceding, loft 20,000 inhabitants by the malady. On the firft: appearance of the plague in Egypt, the magiftracy publifhed an ordinance to prevent the introduaion of the difeafe by infeaion ; but it was of no ufe. The difeafe was preceded, as ufual, by a petechial fever. Mariti's Travels. In England, the fummer of 1760 was dry and autumn wet. In this year occurred another difcharge from Vefuvius.—Ar comet was feen in January, and a diftemper made great havoc among horfes in and about London. Annual Regifter 176a 67. Immenfe damage was fuftained by tempefts. Ibm. 73. 248 The principles of difeafe in 1760 began to exhibit themfelves in the Weft-Indies, and the ordinary fever of the climate affum- ed new and malignant fymptoms, with contagion. Lind,p. 126. In this year alfo the northern parts of the American conti- nent, which had been overrun by meafles, began to feel more fe- verely the violence gf the epidemic conftitution. In November, the town of Bethlem was affailed by an in- flammatory fever, with fymptoms of typhus, which in the courfe of the following winter, carried off about 40 of the inhabi- tants. The difeafe was extremely violent, terminating on the 3d or 4th day; in fome cafes, the patient died within 24 hours of the attack. It feems to have been that fpecies of winter fever, which occurs in peftilential periods, mentioned under the year 1698. During this epidemic, a flock of quails flew over the chimney of a houfe, in which were feveral difeafed perfons, and five of them fell dead on the fpot. This was thought ominous ; but was a natural event, which may rationally be afcribed to de- leterious gas emitted from the chambers of the fick. Med. Repof. vol. 1. 524. This difeafe was afcribed to the draining of the pond or fwarnp, mentioned under the year 1750. But to this explana- tion, there are ftrong, if not infuperable objeaions. Firft. The fever began in November ; but this is the month when the marfh fevers of our climate difappear. I doubt whether the effluvia from marfhes ever aa upon the human body, fo as to produce difeafe, without a greater degree of heat than Con- neaicut ever experiences in the month of November. Cold puts an end to all marfh fevers, but this difeafe continued to in- creafe in December, and did not ceafe till late in the winter. Secondly. This difeafe was called a malignant pleurify ; but marfh effluvia are not known to produce fevers of that defcrip- tion. They are common on high, as well as on low grounds, as I can prove by faas in America. Thirdly. There is no neceffity of reforting to marfh exha- lations for the fource of this malady. The fame fpecies of fever prevailed in that winter and the fpring following, in many other parts of Conneaicut, where no marfh exifted. In Hartford it 249 carried off a number of robuft men, in two or three days from the attack.* In North-Haven it attacked few perfons, but ev* ery one of them died. In Eaft-Haven died about forty-five men in the prime of life, moftly heads of families. The fame difeafe prevailed in New-Haven among the inhabitants, and flu* dents in college. It is obvious then that this was an epidemic, very well known in fickly periods, and not dependent on local caufes. From Dr. Trumbull of North-Haven I have the following remarks on the difeafe. The blood was very thick and fizy; often iffuing from the nofe and fometimes from the eyes. The inflammation was vio- lent, and foon produced delirium. The moft robuft bodies were moft liable to the difeafe. A free ufe of the lancet, in the early ftages of the diforder, was the only effeaual remedy j where the phyficians were afraid to bleed, the patients all died.-J* This malady prevailed from November 1760 to March 1761. I cannot learn that this fpecies of inflammatory fever, has ever been epidemic in the northern parts of America, fince this period. But it is a common winter fever, in the Carolinas, af- ter fickly fummers ; and in the northern ftates, fporadic cafes o£ it occur with all its formidable fymptoms. Inftances will be hereafter mentioned. It is the peftilence of winter, and^arely, if ever appears, except when peftilential epidemics are current in fummer. And I am not without fufpicions that the debility occafioned by marfli effluvia in fummer may predifpofe the fyftem to that fever in winter, tho not neceffary to produce it. In March 1761 was a fmall fhock of earthquake in New- England, and the fame occurred in Iceland, Hamburg, Syria, England and South-America. * One of them was my paternal uncle. f Dr Hugh Williamfon, in the fecond volume of the Medical Re- pofitory, has defcribed this fpecies of difeafe, which, he fays, prevails pften in Carolina in winter, efpecially among thofe who have been af- fected by bilious fevers in the preceding autumn. He obferves that bleeding is ufually pernicious in that difeafe. Perhaps a difference of climates may make different remedies neceffary. But in different pe- riods, the fame difeafe may require different treatment. In New-Eng- land, that fever has ufually demanded an early ufe of the lancet, H h 25° In the winter and fpring of 1761 a fevere influenza attacked the northern parts of America. In Bethlem it was cotemporary with the fever juft mentioned. In Philadelphia it prevailed in the winter, and in Maffachufetts, in April. From Dr. Tufts, a refpeaable praaitioner of medicin in Weymouth, I have the following defcription of the difeafe. " The diftemper began in April, and in May ran into a ma- lignant fever, whieh proved fatal to aged people. It fpread over the whole country and the Weft India iflands. It began with a fevere pain in the head and limbs, a fenfation of coldnefs, fhiverings fucceeded by great heat, running at the nofe, and a troublefome cough. It continued for eight or ten days, and generally terminated by fweating. In May, the aged who had before efcaped, were feized with an affeaion like a flight cold ; this, in a day or two was fol- lowed by great proftration of ftrength, a cough, labor of breath- ing, pains about the breaft, praecordia, and in the limbs, but not acute. The countenance betrayed no great marks of febrile heat. The matter expeaorated was thin, but flimy. As the difeafe advanced, the difficulty of breathing encreafed ; the ex- peaoration was more difficult; the matter thrown off more vifcid ; at length the lungs appeared to be fo loaded with tena- cious matter, that no efforts could diflodge it, and the patient funk under it. This diforder carried with it bilious appearances—the coun- tenances of fome patients were of a yellowifh hue. In fome, there was an appearance of indifference or infenfibility ; and at night, a flight delirium." M. S. letter from Dr. Tufts. In the fpring of 1761 earthquakes were felt in many parts of Europe. See an account of them in An. Regifter, 1761.92. Shocks alfo were felt in the Azores and Weft Indies. Thefe agitations were precifely cotemporary with the epidemic catarrh in America. Scarcely any country efcaped the convulfions of nature. During the peftilence in Theffalonica, fhocks were felt almoft every day. Ibm. In the fummer of 1761, I am informed, the infeaious bilious fever prevailed in Charlefton, but I am not poffeffed of the details. 25I In May happened a moft extraordinary typhon or whirlwind, which fwept Aftily river to its bottom. Five veffels were funk and eleven difmafted. Annual Regifter, 1761. 93. In Italy a woman was killed by a fudden eruption of vapor under her feet. Ibm. 95. The fummer in America was very dry. In the fpring of 1762 the influenza was epidemic in Europe. It appeared at Edinburgh in April in a few cafes; at Dublin in May ; and in June was general and fevere. It was therefore a year later than in America. Effays and Obf. Edinburgh. Rutty on weather. An. Reg. 1762. In March was an earthquake in Ireland, and in autumn a con- fiderable fhock in Spain. On the nth of June was feen a me- teor, paffing from north to fouth, which met a dark cloud and exploded. Another as large as the moon, and bright as the fun defcended flowly on the 4U1 of December, and diflipated. Annual Regifter, 1762. In 1762 appeared a comet, and in America the heat and drouth exceeded what was ever before known From June to September 22d, there was fcarcely a drop of rain, almoft all fprings were exhaufted, and the diftrefs occafioned by the want of water was extreme. The foreft trees appeared as if fcorched. The winter following was equally remarkable for feverity, both in Europe and America. The Thames was a common highway for carriages, and the poor perifhed in the ftreets of London. Lond. Mag. 1763. Annual Regifter, 1762. In America the fnow fell on the 8th of November and con- tinued till about the 20th of March. Thefe extraordinary phe- nomena were followed by an eruption of Etna in 1763, of three months contiuance. In the extremely hot fummer of 1762, the bilious plague pre- vailed in Philadelphia. The fame difeafe fwept away moft of the troops in the expedition to Havanna. The plague raged in Conftantinople and in Syria ; while the yellow fever fpread mor- tality in Bengal. In this year the plague in Aleppo came to its crifis. In 1760, died about 500 perfons ; in 1761, 7000, and in 1762, 11OOO ; after which year it fubfided. See Patrick Ruffel, Hift. of that plague. 25* The bills Of mortality will beft fhow how feverely the. princi- ples of difeafe were felt in London, Amfterdam and Dublin in 1762 and 3. No part of the earth feems to have efcaped a fhare of unufual mortality in the period between 1759 and 1763. In the latter year, the bilious plague in Bengal carried off 800 Europeans and 30,000 natives. Lind, p. 82. In the year preceding, a vio- lent earthquake occurred at Chitacong in the territories of Bengal. An. Reg/ 1763. 60. On the 19th of Oaober 1762, happened a remarkably dark day at Detroit, 'and the vicinity. While at dinner, the inhabi- tants found it neceffary to vfe candles. The darknefs continued, with little interruption, during the whole day. Phil. Tranf. vol. 53. p. 63. Mem. Amer. Acad. vol. r. 244. During this peftilential period, fatal difeafes carried off the cattle on the continent of Europe, and Toulon loft one third of its inhabitants by an epidemic. An. Regift. 1761. 161. The fummer of 1763 was a moift and unkindly feafon. In Auguft the Indians on Nantucket were attacked by the bilious plague, and between that time and February following, their number was reduced from 358 to 136. Of 258 who were af- feaed, 36 only recovered. The difeafe began with high fever and ended in typhus, in about five days. It appeared to be in- feaious among the Indians only ; for no whites were attacked, altho they affociated freely with the difeafed. Perfons of a mixed blood were attacked, but recovered. Not one died, ex- cept of full Indian blood. Some Indians who lived in the fam- ilies of the whites, efcaped the difeafe ; as did a few that lived by themfelves on a diftant part of theifland. I am informed, by refpeaable authority, that a fimilar fever attacked Indians on board of fhips, at a diftance of hundreds of leagues, without any conneaion with Nantucket. In December of the fame year, the Indians on Martha's Vine- yard, diftant eight leagues from Nantucket, were invaded by a like fever ; not a family efcaped, and of 52 patients, 39 died. In this inftance, difeafe difcriminated as nicely between the Whites and Indians, as in 1797, it did between men and cats. 253 and a3 exactly as the plague in Egypt, between the Ifraelites and Egyptians. Some fufpicions were fuggefted that the difeafe at Nantucket might have been received from a fhip which put in there, with fick paffengers, from Ireland bound to New-York ; but there is no foundation for this opinion, as the diforder broke out be- fore the arrival of the fhip. See Phil. Trans, and Lond. Mag. 1764. Hift. Collections, vol. 3. 158. M. S. of Mofes Brown. In 1764, juft after this fatal peftilence among the Indians, a large fpecies of fifh, called blue fifh, thirty of which would fill a barrel, and which were before caught in great numbers, on ev- ery fide of Nantucket, fuddenly difappeared, to the great lofs of the Inhabitants.—Whether they perifhed or migrated, is not known. Hift. Col. 3. 158. In Europe, the year 1763 was remarkable for difeafes among various fpecies of animals. In Denmark, an epidemic catarrhal diforder affeaed horfes. In Madrid, a peftilence among dogs fwept away multitudes—900 died in one day. In Genoa, the poultry perifhed in a fimilar manner. In Italy, horfes and fwine fell viaims to the peftilential principle. In France, horfes and mules; in Sweden, fheep, horfes and horned cattle perifhed r.nder the influence of the general caufe. Rutty on Weather. The fummer was remarkable for hail ftorms, one of which totally ruined 36 villages in Maconnois in France. See the ac- count of thefe and of the earthquakes in that year in An. Regif. Chronicle. Hail ftones fell of fizes from three to ten inches in circumference. Thefe ftorms were numerous and many fire balls fell in various parts of England and a globe of fire was feen in Sweden. Thefe hail ftorms occurred during or near the time of the e- ruption of Etna. In 1764 was another eruption of Etna. In moft parts of Europe and America, this period of peftilence ap- r pears to have clofed with the years 1762 and 3. But in Naples fpread a malignant fever in 1764, preceded by famin, by which difeafe it was fuppofed 200,000 people perifhed. - The difeafe «54 was marked by petechias and glandular tumors and was a mild fpecies of plague. The feafon was exceffively hot, and the bil- ious plague prevailed in Cadiz, Lind, 189. 122. An earth- quake occured in. Portugal and Siberia. In the February follow- ing occured a degree of cold, rarely known in England. The mercury in Farenheit fell to 7 deg. and in one place, within the ball. An. Reg. 1765-66. A remarkable high tide in China in May fwept away a whole city. The caufe is not mentioned. Ibim. 92. To the epidemics above mentioned, fucceeded a feries of dyf- enteries, in the hot fummers of 1765 and 6. In 1765, the ma- lignant dyfentery raged in Berne and other parts of Switzer- land, in Suabia and Auftria. The invafion was, in many cafes fudden, fays Zimmerman, without any preceding fymptom ; but more generally its approach was indicated by chills, laflitude and other premonitory figns. In its progrefs, it exhibited moft of the fymptoms of the yellow fever of America. It was pre- ceded by a putrid fever, which yielded to the dyfentery in June. See Zimmerman on Dyfentery. This epidemic was followed by violent and malignant pleuri- fies ; a circumftance that marks its alliance with the peftilential fever of America, and probably of all temperate climates, which is alfo fucceeded by pleurify or peripneumony in winter. Id 1765 were many earthquakes in Italy, and Sweden, and a volcanic eruption at Truxillo in Spanifh America. Dyfentery prevailed in Scotland, and intermittents in Pennfylvania and Georgia, were univerfal. In 1766 the fummer was every where hot and in Europe ex- ceffively dry. In Germany, the Rhine was lower than in the terrible drouth of 1476, and in many places, was forded. In Scotland, the people were compelled to kill their cattle for want of fodder. The heat and drouth produced great hail ftorms, and in autumn, were followed by inundations, one of which at Montauban, in France, fwept away 1200 houfes. Terrible tem- pefts marked the year, and in the Weft-Indies, thofe hurricanes which lay the iflands wafte, and are recorded among the memo- rabilia of the climate. In Auguft, the planet Mars was nearer 255 to the earth, by two millions of miles, than it had been fbr many ages, and in the fpring appeared a comet. The winter preceding this remarkable fummer, was extremely cold in Europe. At Ratifbon, Reaumur's thermometer was two degrees lower, than in the noted year 1709, and birds per- ifhed with cold. At Naples, the fnow lay in the ftreets, to the depth of 18 inches, and Vefuvius began to difcharge fmoke, the harbinger of an explofion. At Lifbon, Reaumur's ther- mometer was 37 degrees below the freezing point, and at Mad- rid, people fkated on the ice. Thefe remarkable phenomena preceded and attended a gene- ral difcharge of fire and lava, from the three well known volca- noes, Etna, Vefuvius and Heckla, which took place in 1766. This is one of the few inftances on record, in which thefe vol- canoes have been in eruption, nearly at the fame time. The eruption Of Heckla continued from April to September. Thefe phenomena account for the exceflive drouth in Europe. See Sinclair's Scotland. Annual Regifter, 1766. In this year 1766 was an earthquake in New-England, and a violent fhock at Conftantinople. Vegetation failed in fome parts of Europe and America, and grain was very fcarce in Italy, Great-Britain and the Carolinas. In 1767 a million fterling was paid in England for imported grain. An. Reg. 1768. p. ioi.' The winter of 1765-6 was not fevere in America and there was little fnow ; but in this remarkable period, as in many oth- ers, the feverity of the feafons commenced in Europe one year before it did in America. The winter of 1766-7 was terribly fevere in both hemifpheres. The cold was as intenfe as in 1740 ; the Rhine at Cologne became a bridge of ice, and fupported laboring artificers, as in 1670. In Italy, the poor crouded to the cities for aid, and perifhed with cold. In Ruflia, both rich and poor perifhed. The wolves became ravenous, entered towns and deftroyed people. In England, the larks took refuge in hay-carts and the market; the fnow fell to the depth of many feet and buried thoufands of fheep. In America, the cold was * I am ftruck with furprife to obferve how univerfally erops fail, about the time of great volcanic eruptions. 2S6 very fevere, and at Brandywine, the mercury fell in Farenheit to 20 deg. below cypher—an unexampled degree of cold in that latitude. In January happened a thaw, which broke up the riv- ers in Conneaicut, and left fcarcely a bridge over the rivers. The cold in France in 1767-8 was more fevere than in 1740 and within a degree of that in 1709. In Conftantinople fnow and hail fell as late as March 16. See An. Regif. 1767. p. 52, 33, 54, 7& 1768. p. 58, 101, Every thing indicated uncommon agitations in the elements, Pages would be neceffary to enumerate the tempefts and hail ftorms of thefe years. In January 1769 fell two fire balls in England; one of them on Tower hill. At Amiens, a man. his wife and his horfes were killed by a difcharge of fubterraae- ous vapor. A violent ftorm in Virginia on the 11 th of Septem- ber tore up trees, ftranded fhips and demolifhed houfes ; Bag- dadt was almoft ruined by an earthquake, and Cuba was defola- ted by a hurricane in 1768. An. Regifter, 1769. 67. 146. Thefe laft years in England were rainy. In 1767 epidemic catarrh prevailed in Europe, and difeafe? among horfes in New-England and New-Jerfey. The fummer was remarkable for hail ftorms; Cepfialonia was ruined by an earthquake, and Vefuvius, from this year to 1777 never ceafed to difcharge fmoke, and frequently fcoriae, ftones and cinders. An. Reg. 1767. 142, 151. Encyclop. art. Vefuvius. In 1768 vaft multitudes of caterpillars devoured the grafs in the fields at Northampton, in Maffachufetts. The fummer of 1768 was hot, but I have no account of the difeafes in America in this and the preceding year, except of a difj.der in the head and throat among horfes. Mem. Am. Acad. vol. 1. 529. in 1769 the fummer was very hot, and in autumn appeared a ccmet with a vaft coma. Venus paffed over the Sun's difk on the 3d of June ; there was a fmall earthquake in New-England and a great tempeft. Among the difeafes in America is men- tioned a fatal angina in Bofton, and other towns, but I am not furnifhed with its hiftory. The fame diftemper prevailed in 1770, and in Jamaica occafioned confiderable mortality. Mufeum, vol. 1. 35, 430. 257 • In Holland 32,000 cattle perifhed by a peftilential diftem«ef; An. Reg. 1769. 166. Great ficknefs prevailed at Rome. Ibmj In America fome cafes of canine madnefs were obferved. The meafles prevailed in America, but I have no details of its origin and progrefs. The dyfentery was epidemic and fatal in 1769. In July 1770 appeared alfo a comet. There was an eruption of Vefuvius in 1770, and another in 1771. Flames iffued from Heckla in 1771 and 72, but no lava. An earthquake was felt in New-England in 1771, and Italy was repeatedly fhaken. On the 17th of July was feen a meteor or fire ball. Thefe two years were diftinguifhed by the moft terrible earth- quakes, ftorms, rains and inundations, accounts of which fill the gazettes of thofe years. In 1770 the floods in England, Holland and France exceeded any that could be recolleaed. In France the vintage was greatly injured. In 1771 the terri- tory of Honduras was wafted by locufts and famin. An Reg. p. 163. In 1771 great rains continued to occafion floods. In Vir- ginia, a flood in the Rappahannock filled the warehoufes and ruined the tobacco, which occafioned public prayers to be or- dered. Similar inundations happened in Germany. There were earthquakes in Hifpaniola, St. Maure, England, and in Ternate, a Molucca ifland, where was an eruption of fire; Gent. Magazine. An. Regif. 1770, paffim 1771. 120. In 1771 a mortal diftemper fwept away great numbers of foxes in America. Mem. Am. Acad. vol. 1. 529. In Italy the harveft failed, and in Sardinia, Holland, Flan- ders, and fome parts of England, the cattle were fWept away by an infeaious difeafe. The number of cattle that perifhed in Holland, was ftated, in Sept. 1771, to amount to 171,780. An. Regif. 1771. 147. In Conftantinople raged the plague in 1770 ; and one thoufand bodies were, for fome time, buried daily. In 1771 this malady prevailed in Poland and Ruflia, and 200,000 people perifhed. The number that died in the Ruffian dominions was 62,000. An.Regif. 177*. W I i ml In the Eaft-Indies the diforders in the elements at this" period produced ftill more deplorable effeas. The exceflive heat and want of rain, which ufually precede or attend the approximation of comets and volcanic eruptions, occafion a failure of crops in countries, where the grain which is the principal food of the m- habitants, depends on water from inundation. Such is the faa in India and in Egypt, where rice is the great article of food. The heat and drouth of 1769 cut fhort the rice crops in the territories of the Ganges. The confequence was a famin, which, in 1770, deftroyed incredible numbers of the natives. The ftreets were filled with dead carcafes, and fuch numbers were thrown into the river, as to render the water and the fifh unfit for ufe. In 1771 difeafe was added to the calamities of the miferable inhabitants, a million of whom were fuppofed to perifh by the bilious plague. See Encyclopedia, Art. Bengal. In 1770 the atmofphere at Calcutta was filled and clouded with flies of a large kind, which never defcended to the earth, but came fo near that they could be diftinguifhed with glaffes. It is remarkable that the appearance of thefe animals was cotemporary with the millions of worms which overran the northern diftrias of America. Encyclop, Article Bengal, The Bramins mentioned that a fimilar phenomenon occurred a- bout 150 years before,which muft have been during the peftilence among the Indians in America from 1618 to 1622. At this time alfo began a difeafe among the potatoes in Scotland, which has been gradually extending itfelf to this time. The leaves con- traa and fhrivel ; and juft below the furface of the earth, there appears on the ftalk a fear of fome length, or groove corroded through the rind, of the color of ocher. The fruit on the roots is fmall and of an unpleafant tafte. Sinclair's, Scot. 2. 187. In 1771 anginas, in fome parts of America, occafioned a confiderable mortality. Regifter of deaths in New-Haven. Catarrh prevailed in 1771, but was epidemic in America in 1772. The winter of 1771-2 was very fevere in Europe. In , *S9 >- &}Uy--'-- America the month of March 1772 was diftinguifhed for great falls of fnow, beyond what was ever before known. In Bohe- mia, it was computed that 168,000 perfons perifhed in that year by epidemic difeafes. An. Reg. 152. A tempeft in China de- ftroyed 150,000 lives in Canton River. An. R.eg. 1773-P- IC,2- In 17.70, cotemporary with the clouds of flies in India and a moft fatal peftilence among men and catde in Europe, appeared in America a black worm about one inch and a half in length, which devoured the grafs and corn. Never was a more fingular phenomenon. Thefe animals were generated fuddenly in the northern ftates of America, and almoft covered two or three hundred miles of country. They all moved nearly in one direc- tion, and when they were intercepted by furrows, in plowed land, they fell into them in fuch number s as to form heaps. They fought fhelter in the grafs, a hot fun being fatal to them. Tbey difappeared fuddenly about' the clofe of June and beginning of Ny. New-England Farmer, Art. Infect. This fpecies of worni has been feen at other times, and in 1791, in great multitudes. No account can be given of their origin and they feem not to have regular periods of return. In July 1791, the late governor Huntington, a gentleman of care- ful obfervation, informed me, he had expofed fome of thefe an- imals to a hot fun on a dry board, and in a few hours, found them diffolved into mere water. They feem to be generated by fome elementary procefs, and to be the harbingers of peftilence ; at leaft they have preceded difeafes in America. In February 1772 prevailed in America epidemic catarrh. M. S. letter from Dr. Tufts. In this year, the meafles appeared in all parts of America, with unufual mortality. In Charlefton, S. Carolina, died 8 or 900 children. Public prints, Odl. 177a- A mortal fever prevailed alfo in Wellfleet on Cape-Cod, which proved fatal to forty of its inhabitants. Hift. Col. vol. 3. 118. The mortality in Bohemia has been mentioned, and the ficknefs in London appears by the bill of mortality. fi6o This year, 1772, was diftinguifhed for a great hurricane in the Weft-Indies, like thofe of 1766 and 1780. An. Reg. 1772. 140. The anginas of the preceding year continued to prevail in 1772. The winter of 1772-3 was model ate in England, but on the continent more fevere. In February, occurred in America, a remarkable day, ftill known by the name of the cold Sunday. This year, 1773, was in general fickly. In America, the mea- fles finifhed its courfe and was followed by diforders in the throat. After the meafles left the patient, came on a fecondary fever, Which, in fome cafes, proved fatal. Thofe who furvived, lay ill a long time, troubled with an exceflive expeaoration. It feem- ed as if the patient difcharged the amount of his weight. But the moft mortal difeafe, was, the cynanche trachealis or bladder in the throat. In general, there was little canker, but an extreme difficulty of breathing; the patient being nearly fuf- focated with a tough mucus or flime, which no medicin could attenuate of difcharge, and which finally proved fatal. All med- ical aid was fruitlefs, and fcarcely a child that was attacked in fome towns, furvived. This difeafe was fpeedily followed, in fome places by the dyf- entery of a peculiarly malignant type, occafioning mortification on the third day. This difeafe was prevalent and very fatal in New-Haven and Eaft-Haven, in Conneaicut, and in Salem, Maffachufetts. M. S. letters from Dr. Trumbull and Dr. Holyoke. In Philadelphia, the meafles appeared in March, attended with efflorefcence about the neck; at the fame time, catarrh which could hardly be diftingufhed from the meafles. Rufh's Works, vol. %. 238. Cotemporary with thefe difeafes in America, were the fmall- pox and a fatal fever in fome parts of Scotland, and a plague which carried off 80,000 people in Baffora, a town in Perfia, near the Euphrates. In this year, an earthquake funk the town of Guatimala in New-Spain. The year 1774 was more healthy than the preceding; but the fcarlatina anginofa began to fhow itfelf in Edinburgh, and is t6t fome parts of America, efpecially at Philadelphia. On the 4th cf May was a fall of fnow. Rufh, vol. 1. 94, and the Eritifli Med. Publications in that year. The winter pf 1774-5 began on the continent of Europe with unufual feverity. The rivers in Germany were frozen, early in December, and there was deep fnow at Bologna in Italy in Oaober. But in England, the winter was not fevere—an in- ftance which is fometimes obferved in both hemifpheres, that cold and falls of fnow run in veins.* An. Regifter, 1775. 87. and 1774. 173. In 1775 happened a great eruption of fire from a volcano in Guatimala. An. Reg. 136. The fummer was remarkable for thunder and lightning. A halo and mock funs were obferved in England, and a me- teor in America. In Sweden and England, the fummer was dry. In Holland happened a great tempeft and high tide, Nov. 14th. An. Regifter, 172. In 1775 prevailed in England epidemic catarrh, preceded by mild ferene weather. In America prevailed cynanche maligna, with confiderable mortality. It feems to have invaded all the northern parts of America, and in many places if continued to be current with dyfentery for three years. This was the cafe in Middletown on Conneaicut river. In other places, it difappeared in the winter following. M. S. letter from Dr. Betts. Regifters of the firft fociety in Middletown. This peftilential period feems to have commenced with the great agitations of the elements in 1769 and 70, and to have been firft difplayed in the drouth and famin in India, the plague in Turkey, and the infeas and diftempers among cattle in Eu- rope and America ; to which may be added anginas. The pro- cefs was marked by a comet, volcanic eruptions, earthquakes and tempefts, with meafles, influenza and angina, and a feries of moft fatal dyfentery clofed the period. * A remarkaftle inftance has happened, the laft winter, 1798-9—-the weather being very cold, with immenfe quantities of fnow from the Atlantic to the mountains, but very mild in Canada and the weftern country, until the clofe of winter. 262 In 1775 an eruption of water took place from mount Etna, and Lipari, a neighboring ifland, difcharged fire. Encyclopedia, art. Volcano and Lipari. In this year began or very much increafed the mildew of oats Jn Montquitter in Scotland. About the beginning or middle of Auguft, the plant affumes a fiery red color; then black fpots burft forth near the roots, and afcend to the fibers that fupport the ear ; circulation then ceafes, and the grain advances no fur- ther, in maturity. Sometimes it yields a little fruit; at other times none. This difeafe of the oats ftill continues to be very injurious to the parifh ; but in 1789, a year of unufual commo- tion in the elements in the north of Europe, as will hereafter be related, it fpread to a greater extent than was ever before known», This phenomenon has been a fubjea of great refearch among farmers and philofophic men ; but no fatisfaaory caufe has yet been difcovered. Sinclair's Stat. Ace. of Scotland, vol. 6. 131. It is remarkable that the prim in America began to decay and perifh about this period ; and near the fame time, the wheat infea firft appeared on Long-Ifland. I would juft obferve that the difeafe among the oats, and the death of the prim, with the wheat infea, may be new phenom- ena in the natural world ; or certain revolutions which unufual caufes may have induced in animal and vegetable life. About this time, for the year is not recolkaed, there was an eruption of fire at Derby, in Conneaicut, a few rods from Nau- gatuck river ; the only inftance ever known in that place. It happened on a fteep bank where it made a large excavation in the earth, throwing trees and ftones to fome diftance. A light was feen on the fpot in the evening before the explofion. It was accompanied with a loud report, and fome foffil fubftances were ejeaed, which were analized by Dr. Monfon of New-Haven, and found to contain arfenic and fulphur. In 1775 alfo perifhed a bed of excellent oyfters in the har- bor of Wellfleet, on Cape-Ccd, twenty leagues fouth of Bofton. Thefe oyfters had been in great plenty, and furnifhed the in- habitants with no fmall portion of food; but in this year from z6$ fbme unknown caufe, they fickened and perifhed, and have never fince grown in that harbor. Hiftorical Collections, vol. 3. 119. During this fickly period alfo, the oyfters on the fhores of Conneaicut were in an unhealthy ftate, and fometimes excited vomiting in thofe who ate of them. It is remarkable alfo that in 1776 the lobfters in the vicinity of York-Ifknd, all difappeared. This event has generally been afcribed to the firing of cannon in the fummer of that year. But the place where they lived being many miles from the Britifh fhipping, this explanation is not fatisfaaory. It is more proba- ble that they perifhed, or abandoned the ground, on account of the bad ftate of their element. The winter in 1776 was fevere in Europe. The cold ex- ceeded that of 1740. In Denmark the found was frozen and croffed on fledges. The Thames was alfo frozen. An. Regifter, 1776. 114. The fummer of 1776 in America was hot and in the northern ftates rainy. The dyfentery was prevalent in all parts of the if. country, and was terribly fatal to the American troops in New- j York and at Ticonderoga. I was at Mount Independence in j Oaober, and witnefs to the ravages of the difeafe. Of thirteen ' thoufand troops, it was faid that one half were unfit for duty, i It has been cuftomary to afcribe the prevalence of this mortal difeafe to infeaion fpread by the foldiers who returned home from the armies. It is certain that the difeafe was thus introdu- ced into particular families ; but infeaion was the fmalleft among the caufes of the epidemic. In moft places, it originated with- out any communication from the army ; and I was a witnefs of fuch inftances. The difeafe was the effea of a particular ftate of the atmofphere, aided by the feafons. To prove how unfounded is the opinion that the difeafe ori- ginated in the army alone, and fpread from that as from a focus, it will be fufficient to mention two faas. The firft is, that this epidemic commenced in 1773, two years before the war, in which year it was more malignant and fatal, in fome places, than J in any fubfequent year. Witnefs New-Haven, Eaft-Haven and / Salem in Maffachufetts. fcr54 In 1775 a remarkable faa occurred. About one hundred men belonging to Danbury, in Conneaicut, went to join the army on Lake Champlain ; they performed their duty and all returned in good health. While they were abfent, the dyfen- tery invaded the town and carried off more than one hundred of the inhabitants. In this inftance, not a foldier returned from the army, until the difeafe had fiibfided. The fecond faa is, that the fame difeafe has before raged gen- erally in this country, with all its horrors, in time of peace; Witnefs the epidemic at Georgetown in Maryland in 1793, at Derby in 1794 and at New-Haven in 1795. In an efpecial manner, I ought to mention the diftreffing dyfentery, between 1749 and 1753, a time of profound peace, when not a foldiet was feen in the country ; a period when the difeafe was as mor- tal and as general, as between 1773 and 1777. A like epi- demic prevailed in many countries in Europe at the fame time.J I have alfo taken pains to enquire of phyficians in the country, as to the propagation of this difeafe from the army, and am in- formed that the difeafe was as fatal in villages where no inter- courfe was had with the troops, as where there was intercouife. The acquiefcence of all defcriptions of men, learned and un- learned, in the opinion that epidemic difeafes are to be afcribed folely to infeaion or fpecific contagion, has proved extremely injurious to philofophy and to medicin.* The difeafe is infec- tious, but it originates in any place, in particular feafons, whether in peace or war ; and ends at the command of the elements and feafons. It ceafed at the clofe of 1777 in the army as well as country, and without any effort which had not been made in pre- ceding years. It may be obferved further that the dyfentery was and always is, moft prevalent among old people and chil- dren who have leaft intercourfe with the fick, efpecially in the country, where no artificial caufes of difeafe exift. * A man in my father's neighborhood, was drafted to perform a tour of military duty at New-York, during the revolution-war. He was fo much terrified by the apprehenfion of catching the dyfentery in the army, that he hired another man as a fubftitute. The latter went to New-York, performed the duty and returned in health. The draft- ed man remained at home, was feized with the diftemper in a fet* weeks after, and died. £65 In 1777 there was a fmall earthquake in the interior of Eng- land, and the London bill of mortality was higher than ufuaL A volcano in Ferro difcharged difcolered water, but no lava. The meafles appeared in fome parts of America, the fame year. The fummer of 1778 was exceffively hot in America, and fevers of a typhus kind were frequent. In Philadelphia an in- feaious bilious fever marked the fummer and autumn after the Britifh army left the city. Rufh, vol. 3. 162. In general how- ever the year was more healthy dian the preceding fummers. In 1778 the plague was fevere in Conftantinople. It was pre- ceded by a great earthquake at Smyrna. An. Reg. 1778. In the fame year an epidemic angina was mortal at Manchefterin England. In the beginning of the winter fucceeding 1778, there occur- red fome cold weather ; but the latter part was the mildeft ever known. In February 1779, many people along the river Con- neaicut plowed their fields ; and in Pennfylvania the peach blof- fomed. The fummer fucceeding was one of the healthieft ever known in America. In Auguft 1779 happened a moft tremendous eruption of Ve- fuvius ; and about the fame time, the fhips of Capt. Cook, then in a high northern latitude between Kamfchatka and America, were covered with afhes which were fuppofed to be difcharged from a volcano on the neighboring continent. In the fucceeding winter, Tauris, the capital of Perfia, was laid in ruins by an earthquake. See Encyclopedia, art. Vefuvius, Cook's voyage, 1779. The winter following thefe eruptions and commotions was, in America, the fevereft that had been known fince 1741. From Nov. 25 th to the middle of March, the cold was fevere and al- moft uninterrupted. The following was the ftate of the mercu- ry in January by Farenheit's fcale—at Hartford in Conneaicut, lat. 41. 44. K k 266 At sunrise. I---- 2 deg. 15——13 below O 2--- 7 below o 20—— 5 3--H 21--- 6 below 0 4---16 22--- 5 5--- 6 23--- 9 below 0 6---io 24--- 6 7--- 9 25----16 below 0 8--- i below o 26--- 6 below 0 9--- 5 27--- 2 below 0 io---19 28--- 8 below 0 11---26 29---20 below 0 12——11 30---15 13--- 8 31--- 4 below 0 14--- 9 February, 1--- 2 »5---*S 2--- 3 16---10 3---- 0 17----17 4----15 18---13 5-——- 8 below 0 Mean temperature in January at funrife 4 deg—almoft 20 de- grees below the temperature of the fame month in ordinary win- ters. See Cennecticut Courant, January 178a Not only all the rivers, but the harbors and bays in the Uni- ted States, as far fouthward as Virginia, were faft bound with ice. Loaded fleds paffed from Staten-Ifland to New-York j the found between Long-Ifland and the main land was frozen in- to a folid highway, where it is feveral miles in breadth. Chef- apeek bay at Annapolis, where the breadth is 5 and an half miles, fuftained alfo loaded carriages.—The birds that winter in this climate, as robbins and quails almoft all perifhed ; and in the fucceeding fpring, a few folitary warblers only were heard ia our groves. The fnow was nearly four feet deep, in Atlantic America, for at leaft three months. The winter was fevere in Europe alfo ; and on the 14th of January, the mercury at Glafgow fell to 46 deg. below o. 467 On the 19th of May 1780 occurred a day of fingular dark" nefs, in New-England, and it was perceived, in a fmaller degree," as far fouth as New-Jerfey. The heavens were obfcured with a vapor or cloud of a yellow color or faint red. The cloud which occafioned the principal darknefs, paffed over Conneaicut about the hours of 9 and 10, and continued till after twelve* In the greateft obfcuration, a candle was neceffary to enable perfons to read. For fome days before, the atmofphere was fil- led with vapor. Mem. Amer. Acad. vol. 1. 234- On the fame day that this lurid vapor overfpread feveral hun- dred miles of country in America, Etna began to difcharge lava from a new raouth, between two and three miles from its crater. The lava divided into three ftreams of a quarter of a mile in breadth, and in a few days ran fourteen miles. Violent earth- quakes accompanied and followed the eruption. The coinci- dence of thefe events, in point ©f time, well deferves notice. The great difcharges from Vefuvius and a volcano in the Araic regions in 1779, the terrible earthquakes, fevere cold and erup. tions of fire that followed, may perhaps lead us to a rational fo- lution of the phenomenon of the dark day—which has not hith- erto been explained. Courant, Oa. 24, 178°- The plague broke out in Smyrna in the fpring of 1780 but I have no account of its progrefs. The fpring was cool and dry, and catarrhous complaints were prevalent among children, fays Dr. Rufh, vol. 1. 123. The fummer following was hot,* and a bilious remittent was epidem- ic in Philadelphia, accompanied with fuch acute pains in the back, hips and neck, as to obtain the name of the break-boite*- fever. In the midft of fummer, but I do not recollea the precife time, appeared the moft fingular halo about the fun which I ever beheld. I wrote a particular defcription of it, at the time, which is miflaid, and therefore I fhall not attempt to defcribe it * At Hwtford, July 8th, the Thermometer at half after 11 A.M. was at 102, at a P. M. 90 and an half, two degrees higher than it bad been fince 1772. 268 from recolleaion.—Haloes are among the moft certain forerun- ners of tempeftuous weather. On the 2d of Oaober the leeward Weft-India iflands expe- rienced a moft dreadful hurricane ; and on the i Ith the wind- ward iflands were almoft laid wafte by a fimilar calamity. Bar- badoes which is leaft fubjea to thefe tempefts, was laid defolate ; and it was eftimated that 6000 fouls periflied. Houfes, planta- tion-buildings, wharves, piers, fhipping were all overwhelmed in one general ruin. It is faid that, during the tempeft, fome of the iflands experienced an earthquake. Courant, Dec. 12, 1780. Jan. 9, 1781 and Jan. 23, 1781. As hurricanes are occa- fioned by difcharges of elearicity, fome trembling of the earth almoft always attends thofe which are violent, and flafhes of fire are vifible. Indeed the atmofphere appears to be a fheet of fire. Similar difcharges of elearicity attended the tempeftuous earth- quake that deftroyed Nicomedia in 358—that which defeated Julian's attempt to rebuild Jerufalem in 362—the hail-ftorm in Egypt, in the time of Mofes—and that which happened at Man- tua in 1785, to be hereafter related. The canker-worm made extenfive ravages in this period ; but I cannot ftate their rife and decline in different parts of the coun- try. The winter of 1780-81 exhibited nothing worthy of par- ticular notice. In the fpring of 1781 prevailed the influenza, or epidemic catarrh. It began with a fevere pain in the head, proftration of ftrength, coldnefs and chills, the pulfe not quick nor tenfe. The pain in the head lafted about twenty-four hours, and was fucceeded by a pain in the fide, not pointed nor acute, extend- ing to the hips, accompanied with a forenefs, and refembling a rheumatic pain. The cough was troublefome, full, and the mat- ter difcharged of the glandular kind, not well concoaed. Ref- piration was difficult, and a confiderable defluxion on the lungs. In a few cafes, the diforder terminated in 7 or 8 days ; biat ufu- ally not till the 13th or 14th ; altho the patient was feldom con- fined to his bed. The difeafe left a forenefs and weaknefs in the fide, which continued after the ftrength was recovered. Vene- feaion had little effea on the pain in the fide. Epifpaftrics ap- plied to the part gave relief. The diforder was feldom fatal, but 269 its effea were very vifible in the multiplied cafes of pulmonary confumption, in the following year. M. S. letter from Dr. Tufts. In the fummer following no particular phenomena occurred ; the elements were in their ufual ftate, fo far as my information extends ; and in general the country enjoyed good health. A malignant fever prevailed, in fome degree, in New-York, but excited no great alarm. One year after this influenza in America, the fame difeafe pervaded the eaftern hemifphere. Its progrefs was from Siberia and Tartary weftward ; and it reached Europe in April and May 1782 : I have no account of its courfe in America, but it feems to be probable, that it took its direaion from America weftward, and paffing the Pacific in high northern latitudes, invaded Afia and Europe from the eaft. This muft have been the cafe, if the epidemic in Europe was a continuation of that in America. For an account of this epidemic, fee the publications of that year. In 1782 happened confiderable earthquakes in Calabria, du- ring which the mercury in the barometer in Scotland funk within the tenth of an inch of the bottom of the fcale, and the waters in many locks in the highlands were greatly agitated. Sinclair's Statiftical account of Scotland, vol. 6. 622. In Britain the fummer was univerfally wet and cold, and crops failed, in confequence of which a diftreffing dearth affliaed Scot- land in the following year. In America alfo the fummer was cool. Two or three torna- does happened in Vermont and New-Hampfhire, with deluging rains, and in one place hail of enormous fize—the gazette ac- counts fay, pieces of ice were found of 6 inches in length. The latter part of fummer was exceffively dry. In New-Jer- fey, a cedtir fwamp of 20 miles in length and 8 in breadth, taking fire by accident, was totally confumed. The fire penetrated among the roots to the depth of 6 feet.—Corn, grafs, and the very forefts withered. The air was loaded with a thick vapor, for fome days in September.* Mem. Am. Acad. vol. 1. 356. Courant, Oct. 8, 1782. * The reader will judge how far this extreme evaporation and drynefs, indicate the action of the internal fires or electricity which produced the tremendous difcharges from Heckla in the following year. In autumn happened the violent tempeft which difperfed the Englifh fleet from the'Weft-Indies, and in which two or three of the French fhips, taken by Admiral Rodney, foundered. " The winter of 1782 3 was more variable than ufual; and extreme drouth cut fhort the crops in the Weft-Indies. Courant, May ac, 1783. Mem. Amer. Acad. vol. I. 360, On the morning of the 5th ^f February 1783, a thick vapor or fog was obferved over the ifland of Sicily, indicating the agit- ation of the element of fire or elearicity ; and about 12 o'clock, a violent fhock of earthquake laid many houfes in ruins. This was but a prelude to more terrible calamities ; for about feven o'clock P. M. a tremendous fhock laid in ruins the greateft part of Meffina, Calabria and many towns and villages. From 30 to 40,000 perfons perifhed in the ruins. On fubfequent days, many fhocks were felt, but of lefs violence. During the con- vulfions on the 5th, flames were feen to iffue from the neighbor- ing fea. Courant, June 3, 1783, See. On the evening of the 10th, a denfe fog or vapor fpread over fome parts of New-England, having the fmell of burnt leaves. The ground, at the fame time, was covered with fnow. Mtm. Amer. Acad. vol. 1. 361. About this time, for the gazette accounts are not particular as to the month, commenced a moft diftreffing famin in the Car- natic, which afterwards extended to moft of the European fet- tlements in the Eaft-Indies. At Madras hundreds of the na- tives perifhed daily, and the ftreets were filled with dead bodies. The caufe was a four years drouth ; for during the approach of comets, and the aaion of fubterranean fire in other parts of the world, that country is fubjea to exceflive drouth, as happened in 1769. and 70. Courant, June 24, 1783, and July 1, Dec. 5, 1785. In the evening of the 29th of March the heavens were illu- minated with a moft fplendid lumen boreale. The fummer of 1783 was variable in the northern parts of America ; in England, it was hot. In June commenced a moft formidable difcharge of lava from Mount Heckla in Iceland, which continued till the middle of 271 Auguft. The country around the mountain was covered with burning fluid, to the extent of 40 miles, and in fome places, to the depth of 40 feet. The lava fpread over 3600 fquare miles. Previous to this eruption, all the fprings and ftreams of water in the neighborhood had been dried up ; a fure forerunner of the difcharge of fire ; and for fome months before the eruption, the atmofphere over the ifland was filled with a dark, bluifh, ful- phurous vapor or cloud, which was ftationary in calm weather, , but which was fometimes difperfed by winds, and fpread over Europe. See Encyclopedia, article Iceland. During this erup- tion, a new ifland was thrown up, at fome diftance from Iceland. On the 18th of Auguft, foon after the eruption of Heckla ceaf- ed, an immenfe meteor or globe of fire fhot through the heav- ens, from north to fouth, pafling the Orkneys and the ifland of Great-Britain, and burfting with a loud report. Encyclop. art. Iceland. Sinclair's Scot. vol. 6. 633. A part of the fummer was exceffively hot in America- No lefs than thirty perfons in Philadelphia, killed themfelves by drinking cold water. Many putrid fevers were the confequence of the heat in various parts of the country ; as alfo tornadoes and thunder gufts of unufual violence, with hail of uncommon fize, in all parts of America. Rarely indeed has fo much in* jury been done by hail in the fame fpace of time. On the 31ft of May a large meteor or fiery globe was feen at Richmond in Virginia, fhooting from north to fouth. It burft with a heavy report. It will be remarked that this meteor oc- curred about two weeks before the eruption of fire from Heckla, but while the fires or elearical caufes were in agitation, as ap- pears from the cloud of vapor, that was fufpended over the ifland. Courant, Sept. 2, and June 24, 1783, and Aug. 5, and 12. During the immenfe difcharges of fire and lava from Heckla, all parts of Europe, Great-Britain, Italy, Sicily, France and even the Alps were overfpread with a hazinefs in the atmofphere. This caufed univerfal confternation, as a fimilar appearance had preceded the earthquake in Sicily on the 5th of February. The churches were crouded with fupplicants. The French aftrono- mer La Lande attempted to quiet the popular fears, by afcribing the phenomenon to a fuperabundance of watery particles in the 272 earth, from the moifture of the preceding year, which were then exhaled by the fummer heats. But this folution is not fatisfad- ory. It was more probably the fmoke from Heckla, wafted by northerly winds and difperfed over Europe, in an attenuatedform. Courant, Oct. 2%, 1783, and Nov. nth, and 25th. Franklin's Meteorol. Obferv. Mufeum, vol. 1. 473. It is ftill more probable that this vapor was the effea of in- fenfible difcharges of elearicity, combined with aerial fubftan- ces; as in Sicily on the 5th and in America on the 10th of February. In Oaober occurred tremendous gales of wind and high tides which did no fmall damage in the feaports of the United States. The firft, on the 15th and 16th, occafioned the higheft water at New-Haven, which had been known in 40 years. Many other tempefts occurred in September and Oaober ; and from Vermont to Georgia, the gazettes were filled with accounts of difafters from the violence of the winds and rains. Courant, October 21, 1783. On the 29th of November, a confiderable fhock of earth- quake was felt in all the northern ftates ; and New-York expe- rienced two or three fhocks in the morning of the next day. Some of the Weft-India iflands were feverely fhaken, about the fame time, and efpecially on the 4th of December. Courant, Dec. 16, 1783. March 9, 1784. In autumn 1783 fome parts of Europe were deluged with continual rains, and at Rome 5 or 6000 children died of the fmall-pox. About Grenoble raged an epidemic fever. A diftemper among the cattle in Derby in England, oGcafion- ed no fmall alarm, and a royal proclamation was iffued enjoin- ing certain precautions to prevent the propagation of the difeafe. Cotemporary with thefe convulfions of nature, was a moft defolating plague in Egypt, the Grecian Ifles, Dalmatia, Con- ftantinople, Smyrna and in the Crimea. It is not poffible, with the general accounts given of fuch an epidemic, in the public prints, to ftate, with any precifion, its origin and progrefs in the eaft. It is mentioned to have appeared in Smyrna, in the fpring of 1783, and it certainly raged in Conftantinople, and many »73 other parts of Turkey in the following fummer, as well as on the north of the Euxine. Courant, Jan. 17, 1784. July 6. Sept. 21, and 38, 1784. In Egypt the fame difeafe committed moft terrible ravages in r783-4 and 5. It began in November 1783. To this calami- ty was added a fevere famin ; the inundation of the Nile, in the fummer of that year, having proved infufficient. So fevere was the plague, that in the winter after 1783, fifteen hundred dead bodies were carried out of Cairo in a day ; and the plague and famin of that and the fucceeding year, was fuppofed to car- ry off one fixth of the inhabitants of Egypt. See Volney's Travels, vol. 1. 192 and 3, and Courant, Oa. 28, 1783, and Oa. 17, 1785, in which it is faid that in Cairo 3000 perifhed in a day in April, 1785. We have then an exaa general view of the phenomena whichj introduce and accompany peftilence in Europe, Africa and Afia1 —terrible earthquakes and eruptions of volcanoes ; exceflive drouth in America, India and Egypt, failure of crops and famin —meteors, great heat and deluges of rain, in other countries. Let us now fee what followed thefe abovementioned agitation? of the elements, in our country. See Cnurant, April 27, 1784, and Jan. 27, 1784, and June 8. In Auguft 1783, the fcarlatina appeared in Philadelphia and in September it became epidemic. It appeared about the fame time in Salem, in Maffachufetts. It was in Charlefton, South- Carolina in 1784, in which year, it appeared in the interior o£ the northern ftates, as in Vermont and New-Hampfhire, and in Middletown, on Conneaicut river. It continued to prevail about five years; but was not fevere in general and many towns wholly efcaped its attacks. Rufh, vol. 1. 141. Mufeum, vol. 2. 562. Mem. Amer. Acad. vol. 1. 369. Belknap's Hift. New-Hampfhire, vol. 2. 121; Regifter or deaths at Middletown. In 1787 the cynanche maligna was epidemic at Northampton, in Maffachufetts. M. S. letter from the Rev. Mr. Williams. The meafles appeared in America in 1783 ; at Salem as early- L 1 274 as May. I find it in all parts of America, in that year, btofc cannot trace the progrefs of the epidemic. During this period neither dyfentery nor peftilential autumnal fevers made any considerable ravages in America, as far as I can learn ; except at Fell's-Point in Baltimore, where the bil- ious peftilential fever occafioned a mortality in 1783. Many fporadic cafes of a fimilar fever appeared in various parts of the country, and almoft a whole family in New-Jerfey periflied by it in the autumn of that year. Fortunately however the confti- tution of the elements was correaed, without producing its moft fatal effeas. Even the fcarlet fever, with the exception of a few places, was lefs malignant than it has been in the laft period. This peftilential conftitution was felt alfo in the north of Eu- rope. The fcarlatina broke out in Edinburgh in the winter of 1782-3, a few months before it did in America; but of its progrefs I have no account. It appears to have been epidemic in London in 1786 ; fo that its period was of about the fame duration as in America. The cotemporaneoufnefs of this fpecies of difeafe in Great-Britain and America} deferves particular no- tice. In December happened a fog in Amfterdam of fuch denfity as to occafion complete obfcurity for three hours in the middle of the day. It was not poffible for perfons to find their way in the ftreets, and many paffengers and fome carriages fell into the canals. Courant, March 9, 1784. The feverity of the winter fucceeding thefe phenomena, both in Europe and America, correfponded with their extraordinary number and violence. The weather was lefs uniformly cold than in 1780, but the froft, in fome parts of the winter was moft intenfe. The following was the ftate of Farenheit's ther- mometer, at Hartford. February 10th, 1784, . 19 deg. below 0. 11 . . 12 do. 12 . . . 13 do. 13 • 19 do. 14 ... 2© do. 575 February 15 . . 12 deg. below 0. 16 . . .16 do. 17 . . 16 do. On the 20th of January was difcovered a comet in Pifces, which was involved in a luminous atmofphere. It was vifible about four weeks. The fevere cold commenced early ; the Delaware at Philadel- phia was clofed at the beginning of December, and continued bound with ice till the middle of March ; notwithftanding a re- laxation of cold and a heavy rain in January. The gazettes ftate that fuch intenfe cold had not been known in that city, fince 1750-51___The Miflifippi was reported to be covered with ice, as far fouth as New-Orleans. At the breaking up of winter, the thaw was fudden, and immenfe bodies of ice, floating down the rivers, which were greatly fwelled, fpread ruin along the low lands on their banks. Great damage was fuftained on the banks of the Schuylkill, Sufquehanna, Potomack and James rivers. Courant, May 11, i 7 84- Feb. 24. March 30. April 11. In Europe, the winter was no lefs fevere—an inftance in which a feverely cold winter in Europe coincided in time, with the fame in America. It may be remarked alfo that this win- ter was juft one century after the coincidence of like events ; the winter of 1683-4 being equally fevere in both hemifpheres. In 1783-4 the river Liffey in Ireland, the Thames in Eng- land, and all the rivers in the interior of Holland, were cover- ed with folid ice. In Holland, the ice gave way about the firft of March, and the rivers being greatly fwelled, the adjacent country was inundated, with immenfe lofs of lives and property. The river Waal, near Nimeguen, broke through its dikes and overwhelmed 34 villages. The Rhine from Cologne and Man- heim, exhibited fimilar fcenes of devaftation. Courant, April 27,1784, and May 18. In January a terrible tempeft fpread defolation along the coaft of France from Rochelle to Bourdeaux; veffels at fea fhipwreck- ed, and houfes on land blown down. This happened on the night of the 17th. Its violence extended along the coaft of Spain and Portugal. An earthquake accompanied this hum- &j6 Cane. The coaft of Italy did not efcape, and fo high was tho fwell of the ocean, that fifh were lodged on the houfes in Syra- cufe. Courant, May 18,1784, and June 1. This remarkable tempeft happened juft before the appearance of the comet. The fpring was wet and cold ; and repeated fnows fell in April. The heat of fome part of the fucceeding fummer in America was extreme. The following obfervations were made at Hart- ford. See Courant, June 29 . June 24th at 2 p. m. 97 deg. by Farenheit. 25 2 p. m. 96 26 at funrife, 80 at 10 A. m. 96 at 2 p. m. 100 at 3 p. m. 101 at 4 p. m. 100 at funfet, 91 at 10 p. m. 80 27 at funrife, 82 at 7 A. m. 91 This extreme heat, as ufual, produced moft violent hurricanes or thunder gufts, with hail of unufual fize. In May, pieces of ice fell in South-Carolina of nine inches in circumference. On the 17th of Auguft the fouthern part of Conneaicut was fwept by a tornado, which levelled trees and buildings and did great in- jury. The beginning of fummer was very dry ; but frequent fhowers afterwards refrefhed the earth, and good crops fucceeded. Courant, Auguft 10, 1784. Auguft 24 and 31. See alfo Ap- pendix to a Sermon preached at Hartford on the death of If- rael Seymour, who was killed by lightning. A great eruption of Vefuvius happened on the 10th of May. Sicknefs prevailed in Leghorn and other parts of Europe. The plague raged this year alfo at Smyrna, Conftantinople and in Dalmatia. Spolatro was nearly difpeopled. The heat in Eu- rope was great and Hungary was overrun by locufts, which de- voured the fields of grafs and corn. A fevere earthquake at the . 277 fame time, fhook the country of Armenia, and its vicinity, and a town was demolifhed with the lofs of 6000 inhabitants, on the 21 ft of July. The plague raged alfo in the regency of Tunis on the African coaft. Courant, Aug. 31. Supplement to do. Nov. 9. On the 30th of July a tremendous hurricane laid wafte a con- siderable part of Jamaica, fweeping away buildings, canes, fruit- trees and overwhelming all the fhipping in the harbors. Courant, Sept. a8, 1784, andOdc. 26. In Oaober, according to the public prints, Barbadoes was fe- verely fhaken by an earthquake. On the 25th of November was a very violent tempeft from the N. E. and S. E. by which means, a moft extraordinary tide was brot into our harbors from the St. Lawrence to New-York, and probably further to the fouth. Great injuiy was fuftained by lofs of fhipping, and of property ftored near the wharves. Courant, Dec. 7, 1784. The great rains fwelled Conneaicut river to the height of ufu- al fpring floods. A meteor was feen in New-England on the evening of De- cember 13, 1784, pafling rapidly from fouth-eaft to north-weft, and burfting with a loud report. The winter following exhibited nothing very worthy of re- mark. In Europe it was colder than ufual, and in America, it produced great fnows, the melting of which in the fpring fwelled Conneaicut river to an unufisal height. On the 13th of March 1785, there was an eruption of fire in the river Majuro, in the province of Palermo, in Sicily, which occafioned a large chafm in the earth. Courant, July 4, 1785. In America canine madnefs began to rage and fpread in all parts of the northern ftates. The gazettes of 1785 abound with accounts of the dreadful effeas of this fingular difeafe. It will be remarked that epidemic madnefs of dogs is one of that fe- ries of difeafes which belong to every peftilential period. When- ever the human race are generally afiliaed with epidemics, the canine fpecies rarely efcape the effeas of the general principle; and not unfrequently foxes, wolves and other wild animak, ex- 27S ferience its malignant effeas, and run mad. In 1785, the teat* latina anginofa was prevalent in the northern ftates. This was in the midft of the period, and almoft every gazette announced fome new cafe of hydrophobia. See Courant, Aug. I, 1785. Aug. 8 and 29. The wheat-infea, which has been ignorantly and improperly hamed the Heflian Fly, committed uncommon ravages in this year. The precife time when this infea originated, is not afcer- tained, probably about the year 1776, or a year or two earlier. Little notice was taken of it, for two or three years. In 1780, Mr. Underhill of Long Ifland loft his wheat crops by the in- fea ; and in fubfequent years, it penetrated into New-Jerfey, travelling, according to common opinion, about 15 or 20 miles in a year. In 1785, it occafioned unufual deftruaion of wheat —and fuch was the alarm in England, for fear it fhould prove infeaious, and be introduced into that country, that the King if- fued a proclamation dated June 25, 1788, prohibiting the im- portation of American wheat.—This event excited no fmall un- eaflnefs in America, efpecially in the ftates, whofe ftaple is wheat. Whereupon the Supreme Executive Council of Pennfylvania re- quefted the opinion of the Agricultural Society, as to the man- ner by which that infea is propagated. To this requeft, the So* ciety returned for anfwer, their decided opinion that it is the plant alone which is injured by the infea ; that the grain is found and good, and that the infea is not propagated by fowing wheat which grew on fields infeaed with it. See Mufeum, vol. 4. 244. Am. Magazine. The prohibition by the King and Council of Great-Britain was deemed a judicious precaution ; but was the fruit of an error that pervades the world, refpeaing the powers of infeaion and contagion. The opinion of the Agricultural Society is well foun- ded, but it remains for time and the force of truth to convince th» people of Philadelphia, that the yellow fever can no more be tranfplanted and rendered epidemic by infeaion, than the wheat- infeft. Both are difeafes, originating where they have a fuitable aliment, and ceafing to exift, when that aliment fails. The prohibition of the Britifh government was repealed the next year j under the apprehenfion of a dearth. 279 The fummer of 1785 was exceffively dry in France and Eng« land and fevers very prevalent in France. In Holland fuch ft drouth could not be recolkaed by the oldeft man living. The canals, rivers and wells were almoft totally exhaufted. In the firft part of fummer, there was not a drop of rain for three or four months, and cattle were fed upon the leaves of the trees* The drouth was nearly as fevere in the Weft-Indies. Courant, Auguft 8, 1785, and 29th—alfo Sept. 12 and 19, In North-Carolina, the fields were overrun with bugs, which threatened a deftruaion of the grain. Courant, Auguft 29, 1785. The fummer contained fome exceffively hot days in America, as well as in Europe. Courant, Sept. j. On the 25th of Auguft happened in the Weft-Indies one of the moft dreadful hurricanes ever known, and equal to that of 1772 or that of 1780. This tempeft was preceded by very fultry heat, and the phenomenon called looming, by which diftant ob« jeas at fea appear to be raifed higher or brot nearer than at other times. I have often noticed this fingular effea of the power* of refraaion in the air, previous to ftorms, of which it is the ufual forerunner. Guadaloupe, St. Croix and the other wind- ward iflands were laid defolate by this tempeft. On the 27th of Auguft, the leeward iflands fuffered a fimilar calamity. On the 24th of September, an eafterly ftorm brought into the riv- ers in the fouthern ftates, as high a tide as ever was known.— Norfolk was inundated, with great lofs. Sicknefs was very general in many parts of the United States. The fcarlatina was prevalent, and the gazettes mention a pre- cina in Ulfter in which died almoft every child under fix years of age. Many adults alfo fell viaims to this or other maladies. See Courant, Oct. 3, 1785, and 0• It is remarkable that this tempeft in the United States wa3 but two or three days after a tremendous hurricane among the windward iflands, which was fuppofed to do more injury than the great tempeft of 1766. At the leeward alfo the fame calamity befel the iflands. In Martinico the barometer fell nearly to 27 inches. Caurant, Oct. 27, 1788. About the fame time fimilar difafters befel Fiance and Eng- land. A tornado of great violence occurred about Paris, in which, the gazettes declare, fell hail-ftones of 8lb. weight. Du- ring a tempeft in London, a fire ball entered a houfe and ftruck down two perfons. Courant, 0&. 27, 1788. In the Weft-Indies hurricanes were repeated in September with deftruaive rage. On the evening of the 17th of Oaober 1788 was feen, at various places, in Conneaicut and New-York, a meteor or fire ball, whofe apparent diameter was equal to that of the fun in the meridian. It paffed from the eaftward to the .weftward with amazing rapidity, illuminating the earth, and approaching neat the weftern horizon, it burft with a heavy report.* Courant, Oct. 27, 1788. The comet already mentioned firft appeared about this time. It rofe about 3 o'clock in the morning in the north-eaft. A violent north-eaft gale occurred on the nth of November. Courant, Nov. 3 and 17. This fummer in America was very rainy ; earthquakes hap- pened in Italy and Mexico ; and a fhock was felt in July in the ifle of Man. Sinclair's Scot. vol. 6. 62$. The thermometer on one day in July rofe to 103 in Colum- bia College, in New-York; but the general heat of the fum- mer was not exceflive. Mufeum, vol. 7. 36. * This meteor was feen at Poughkeeptie, on the Hudfon, nearly in the zenith. In Suflex county, weft of Cape Henlopen, it appeared to be about ten degrees above the horizon. Courant, Dec. 8,1788. 28$ In November 1788 appeared the meafles in New-York. On its firft invafion, it appeared with great malignity. The fame diftemper appeared in the northern liberties of Philadelphia, in December ; and fpread till it became epidemic in February and March. Courant, Nov. 24, 1788, andRufh.vol. 2. 234- The eaftern parts of Europe were fickly during the fummer of 1788. The immenfe armies on foot, in the war between the Auftrians, Ruffians and Turks, contributed to increafe the mortality. It was eftimated that 8o,oco Auftrians perifhed, moftly by difeafe. The year however was generally healthy. The winter of 1788-9 was colder than ufual in the United States. On the morning of the 2d of February, the mercury in Farenheit fell to 28 deg. below cypher ; 4 degrees lower than had before been obferved in Hartford. The feafon how- ever was on the whole lefs fevere than in 1780 and 1784. Courant, Feb. 2, 1789, and 9th. In Europe, the winter appears to have been unufually fevere. The froft penetrated to the fouthern parts of Spain and Portu- gal ; and the rivers in Eftremadura and Alantejo were covered with ice. The Pyrenees were involved in deep fnow in March. Courant, Aug. 3, 1789. Univ. Mag. 1789. It fhould have been related under the year 1788, that almoft all the cod-fifh taken on the banks of Newfoundland, in that year, were thin and fickly; when dried, they were of a dark or bluifh color, little better than fkeletons, and not well received in foreign markets. This condition of that fifh was confined to thofe banks ; as the cod taken at other places were in their ufual ftate. M g kttcr ffom Dj. Holyoks# On the 28th of May 1789. appeared in Conneaicut a moft fingular halo, of which the public prints contain a particular de- fcription. This phenomenon feems to indicate the approach of tempeftuous weather, and was in this inftance, followed by a heavy wind and rain. But when this appearance is of fingular brightnefs or extent, it indicates a ftate of the atmofphere highly elearified perhaps and certainly tempeftuous, and ftorms are numerous and violent. Thus the remarkable hurricanes of zS6 ry8o were preceded by as remarkable haloes. The halo of May 28th was preceded by a moft fplendid lumen boreale. The inftance under confideration was furprifing and to gloomy minds, awful. A clergyman, fince dead, wrote a moral effay on the occafion in which he prediaed great calami- ties to happen ; and he mentioned other events, of that period, as unufual numbers of flies, caterpillars, locufts, and dearth oF corn, in confirmation of his opinion that the arm of the Lord was extended in wrath over our land. Courant, June 8, 1789, and June 15. It is true that our crops had been thin, in the preceding year, and the northern ftates, in the fpring of 1789, experienced a dearth, approaching to famin. In Vermont, people were re- duced to the neceflity of feeding on tad-poles boiled with pea- ftraw. In one inftance four potatoes fold for nine pence. None of the human race were aaually ftarved to death, but a few died of a flux in confequence of bad diet.* Cattle however perifhed in confiderable numbers. Such were the gazette ac- counts of the day. It is certain that a fimilar fcarcity had not been experienced in America for many years. Whether the failure of crops and the fickly ftate of the cod-fifh marked a de- rangement of the elements, let the philofopher determin. Courant, June 15, 1789, and Jane 42. The fpring of 1789 was cold and vegetation tardy, beyond what could be recolkaed by the oldeft perfons living. Part of the fummer fucceeding was exceffively hot. For nine or ten days fucceflively, in Auguft, the heat was above 90 deg. and in the midftof the day, it rofe nearly to 100 deg. The mean temperature of the fummer was however not much above what is ufual. Rufh, vol. 2. 234. Courant, Aug. 24 and 31. On the 4th of June ice at Wioming was as thick as window glafs. Courant, June 22. The failure of crops in the Carnatic in 1788 occafioned a fe- vere famin, by which thoufands perifhed in the fucceeding year. Courant, April 27, and Sept. 28, 1789. The hydrophobia fhowed itfelf in America early in 1789. * In old fettlements, there was food enough for man, but the failure of a'furplus in this country, is a rare event. 287 A man in Coeyman's precinct, ftate of New-York, died in July of that dreadful malady, taken as was fuppofed, by fkinning a cow that died of the diforder in the April preceding. Courant, Aug. 3, 1789. In Maryland, the autumn was diftinguifhed by an unexam- pled mortality among horfes. Courant, Dec. 31, 1789. In Europe alfo crops had failed, and England, Holland and France apprehended the moft calamitous effeas. In Paris the cry of bread, bread was every where heard, and many riots and mobs marked the diftrefs of the inhabitants. Courant, Oct. ia, 1789. The empire of China experienced the fame calamity, and the people fuffered indefcribable diftrefs from famin and difeafe. In Madras died 30,000 people by famin in 1788. Courant, April 27, 1789. In this inftance, crops failed over the whole earth, in the fame year. On the 1 oth of July a moft tremendous earthquake convulfed Iceland. Large chafms were opened in the earth, and fome mountains were rent afunder. Several fhocks happened on fub- fequent days, and a violent fhock in September is mentioned in the 6th volume of Sinclair's Statiftical works, 625. Courant, January ai, 179a On the 30th of September occurred a violent earthquake in Tufcany, by which fome villages were deftroyed and feveral thou- fand lives. On the fame day, but not at the fame hour, a fmall fhock was felt at Edinburgh. On the 5th of November, a fhock was felt at Crieff, 50 miles from Edinburgh ; and on the 1 oth and 1 ith, fevere fhocks were felt at other places. Courant, Dec. 7, 1789. Sinclair, vol. 6. 635. On the 4th of December arrived at Lieth, Capt. Stewart of the fhip Brothers, from Archangel in Ruflia ; who informed that on the coaft of Lapland and Norway, he failed many leagues among multitudes of dead haddock floating on the water. He fpoke feveral fhips which alfo paffed among them. Sinclair, vol. 6. 627. Whether thefe fifh were killed by an earthquake or a difcharge of fubterranean vapor or heat, or died by ficknefs, is not known. 288 If they were killed, it would feem probable that other fifh in the fame feas, would have fhared the fame fate ; which does not ap- pear to have been the cafe ; for the accounts make no mention of the death of other kinds. And what renders it probable that they died of difeafe, and a difeafe peculiar to that kind of fifh, is, that for fome years after, no haddock came to the markets in Scotland, as before that mortality. That fpecies appeared to be almoft extina ; whereas there is no mention made of a failure of other kinds of fifh. Careful obfervations and precife dates would afiift our refearches into the caufes of thefe wonderful phenomena. In Oaober, Vefuvius was in a ftate of eruption for feveral weeks, and difcharged fmall ftreams of Lava. The plague pre- vailed at Conftantinople and Smyrna. Gent. Mag. 1789. On the 29th of Oaober from 2 o'clock P. M. to half after 4, Kentucky was enveloped in thick darknefs, fo that people were dbliged to ufe candles. Courant, January 14, 1790. It will be obferved that this darknefs, and the beginning of the influenza in America coincide nearly in time v/ith the erup- tion of Vefuvius, and many earthquakes. Such univerfal diforders in the elements never fail to produce epidemic difeafes ; and thofe here related were the heralds of the moft fevere period of ficknefs that has occurred in the United States for 30 years. The firft appearance of that feries of epidemics to be hereaf- ter defcribed, feems to have been in the meafles at New-York in November 1788, and at Philadelphia in December following. This difeafe became epidemic over the northern ftates in 1789, but I have not the means of defcribing its progrefs. I find, in bills of mortality, from various places, deaths by meafles are mentioned in 1789 and 90. In autumn 1789 appeared the influenza or epidemic catarrh. The precife time and place of its appeapance, are not afcertained. Some accounts fay, it originated in Canada. But I fhall con- fine my obfervations to its progrefs in Atlantic America. It was firft obferved about the cicf. cf September 1789, in New-York; 28g and Philadelphia. Dr.* Rufh informs me, that it was brought to Philadelphia by the members of Congrefs, who returned from New-York, about the firft of Oaober. Another account, writ- ten by one of the faculty in Philadelphia, and publifhed in the 7th volume of the Mufeum, mentions its firft appearance there, about the time of the Friends Yearly Meeting, in September. The precife time is probably not afcertainable ; the opinion of its propagation by infeaion is very fallacious, as I know by repeat- ed obfervations. It probably appeared in detached cafes, fome days before it became a fubjea of obfervation. Mufeum, vol. 7. 231. From the middle ftates, it moved rapidly over the whole coun- try. It appeared in Hartford, where I then refided, about the middle of Oaober. On the 19th of that month, I left Hart- ford for Bofton and arrived the next day in good health. I was feized with the influenza on the 23d, and by the aid of a dilu- ting regimen, recovered in four days. No perfon who attended me was feized with the diftemper, fooner than the other inhabi- tants of that town. I mention this to difprove the common opin- ion of its infeaion ; not that I deny it to be in a degree, infec- tious ; altho my own obfervations do not warrant that concef- iion ; but I aver that its propagation depends almoft entirely on the infenfible qualities of the atmofphere. Two ladies who left Bofton with me on the fecond of November, before the difeafe had appeared in their family, and before it was a fubjea of con- verfation, were feized with it in Hartford, at the fame time, that it became epidemic in Bofton, one on the 8th and the other on the 12th.—The difeafe had then paffed Hartford, and there is no evidence of their beingexpofed to any perfon infefled. This faa fhows a regular progrefs in the ftate of air producing the dif- eafe—as perfons leaving Bofton and travelling one hundred and twenty miles diftance, were effeaed precifely at the time the difeafe became epidemic in that town. This difeafe pervaded the wildernefs and feized the Indians^- jt fpread over the ocean and attacked feamen a hundred leagues from land, and as to infeaion, entirely infulated—it appeared in the Weft-Indies nearly at the time it did in the northern N n $9° ftates. It overfpread America, from the 15th to the 45th de- gree of latitude in about 6 or 8 weeks j and how much further it extended, I am not informed. It fhould have been mentioned that, in September, anterior to the invafion of the catarrh, the fcariatina anginofa appeared in Philadelphia ; but in Oaober it yielded to the influenza, the controlling epidemic. The fcarlet fever re-appeared in Decem- ber, and became epidemic ; often blending itfelf with the influ- enza. It exhibited one predominant feature of the whole feries of fucceeding epidemics, a prevalence of bilious matter, which was often difcharged by purging and vomiting. This difeafe con- tinued to prevail in Philadelphia, and if my information is cor- rea, in fome parts of New-Jerfey, till the fpring of 1790. The meafles occurred in fome cafes, but was not epidemic. Mufeum, vol. 7. 120, 175. It is remarkable that the fcarlatina anginofa was cotemporary in Edinburgh with the epidemic meafles in America in 1789, and nearly fo, with the death of the haddock on the coaft of Norway. It will be obferved that the fcarlet fever, tho epidemic in Philadelphia, did not fpread over the country in 1790. It was little known in the northern ftates, till two years after—this is among the proofs that this difeafe does not depend on infeaion for its propagation. If infeaion was its only or principal means of propagation, the fomites exifted in great abundance, in par- ticular places in 1790, and fufficient to have fpread it over the United States. But a difeafe however infeaious, will not fpread far in an atmofphere that will not generate it. Indeed fcarcely a year paffes in which" fporadic cafes of fcarlatina, or anginas of other kinds do not appear in particular places ; but they never fpread without fome uncommon concurrence of caufes. The winter of 1789-90 was one of the mildeft that is ever known in this country ; there being little froft, except for a few days in February. There fell frequent fnows and in great abun- dance ; but they were immediately followed by warm foutherly winds, and diffolved. Early in the fpring of 1790 we had a fecond epidemic ca- tarrh. I was attentive to its origin and progrefs. I found it at 2<)l Albany in the laft week in March, and heard of it in Vermont about the fame time. I returned to Hartford, but altho expofed repeatedly to its infeaion on my journey, I was not feized earlier than others in Hartford, where the difeafe appeared about the middle of April. It fpread to the fouthward, arrived at Phi- ladelphia near the clofe of that month, and difappeared in th;: city about the middle of June. In the northern ftates. as fac as my knowledge extends, the difeafe was more violent, than ir. the preceding autumn. Many plethoric perfonr c: iv.m habit almoft funk under it; while confumptive people and hard drink- ers fell its viaims. Mufeum, vol. 8. 65. The fpring and fummer of 1790 were moftly rainy ; but oth- erwife feafonable weather. No remarkable epidemics prevailed, except thofe already defcribed, but an increafe of mortality, in fome places, is vifible in the regifters of deaths. Severe earth- quakes occurred on the African coaft, Let it be obferved that the meafles appeared in autumn 1788, juft after great volcanic eruptions, and a moft tempeftuous fum- mer, when the element of fire appeared to be in univerfal com- motion ; juft after the meteor, and during the appearance of the comet.* Let it be obferved alfo that the harveft failed, at this time, in China, India, Europe and America, and let any man deny the all-controlling influence of the elements in producing thefe events. The winter of 1790-91 commenced early and with fevere weather. The laft week in November was cold ; Conneaicut river at Hartford was clofed with ice on the 9th of December, and not open till'the 12th of M«irch. On the whole, the feafon was not of unufual feverity. The fpring and early part of fum- mer were, in moft parts of die country, very dry, until, the middle of June. On the 15th of January, a confiderable fhock of earthquake was experienced at Richmond in Virginia. At the fame time catarrhs were fo prevalent in that ftate and in Pennfylvania, as to excite an apprehenfion of another vifit of the influenza. * In 1732 a dark day occurred in Auguft preceding the influenza. Io 1789 a darkneft at Kentucky occurred, during the epidemic catarrh. 292 Inflammatory difeafes were very frequent during the winter. In Philadelphia the fcarlatina anginofa appeared late in January and was very prevalent in February. In the interior of Carolina it was fickly, but I have no particulars. The whooping cough prevailed in many parts of the country. Courant, Jan. ai, 1790. See Mufeum, vol. 9. 6j. In the month of. April, fome fifhermen at the Narrows, near New-York, caught fourteen thoufand fhad at a fingle draft ; to fecure which, it was neceffary to add feveral feines, one upon the other. This circumftance is mentioned, becaufe feveral medical authors have related that an extraordinary abundance of fifh is among the precurfors of peftilence. It will be noted that the peftilential fever, which has prevailed for many years paft, firft appeared in New-York, in the autumn fucceeding this fin- gular draft of fifh. Courant, April 25,1790.* On the 16th of May, at half paft 10 o'clock P. M. in a ferene, moon-light night, an extenfive earthquake was felt in the northern ftates. It was preceded, a few feconds, by a rat- tling found ; its duration was fhort ; its courfe as ufual in Amer- ica, from N. W. to S. E. No injury was fuftained. Courant, May 23. On the morning after the earthquake, was obferved at Mid- dletown in Conneaicut, a fubftance like honey or butter, cov- ering the grafs and earth for a confiderable extent. See an ac- count of a fimilar phenomenon in Ireland under the year 1695. To thefe phenomena fucceeded in Conneaicut the generation of millions of that fpecies of black worm, defcribed under the year 1770. I believe they were far lefs numerous than in 1770 ; they however appeared in Hartford and in Norwich, and dif- appeared at the fame time. They were very deftruaive to the grafs and corn, but their exiftence was fhort; all dying in a few weeks. * It may excite furprife that there fhould be fuppofed a connection between an uncommoa abundance of fifh, and peftilence. But the theory that refolves this into the unufual powers of excitement, is ra- tional. The ftate of the elements that caufes peftilence, always pro- duces unufual numbers of infects; and often the human race is more prolific than at other times. See the London Regifters of births and deaths. Mait. Hift. Lond. ^93 A paragraph in a Maryland paper dated June i, 1791, men- tions animals, there called caterpillars, but evidently the fame fpecies of worm. They are reprefented as marching in legions from place to place, and devouring the grafs. About the fame time appeared at Lanfingburg on the Hudfon, a fpecies of worm that greatly injured the fruit-trees. Courant, June 25, 179a. But the moft extraordinary phenomenon was the exiftence of die canker-worm, in numbers before unexampled. Whether thefe animals had made their appearance in the preceding year or not, I do not recollea. But in 1791 they devoured the or- chards over the New-England ftates ; and their ravages were re- peated in the two following years. Orchards, ftanding on ftiff clay and in low grounds which are wet in fpring, efcaped ; but on every fpecies of light and dry foil, the trees were as dry on the firft of June, as on the firft of January. Many trees have never recovered from the effeas of their ravages. Another worm of a diftina fpecies, and called at the time, palmer-worm, overfpread our forefts in this or the next year, devouring the leaves of oak and other fpecies of wood. It is a prevalent opinion that uncommon flights of wild pigeons in America, indicate the approach of a fickly feafon. I am not inclined to credit any popular opinion, without good grounds ; but this feems to have been formed on a long feries of obferva- tions. Certain it is that pigeons in the fummer of 1791 were unufually numerous. In Maine, there were traas of foreft of miles in extent,the trees of which were covered with their nefts. Courant, July ir. The fummer of 1791 was exceffively hot. At Salem the thermometer was at and above 80 deg. no lefs than c^ days, and above 90, twelve days*—an inftance that had not happened in many years, in that cool place ; altho it often happens in the middle ftates. Mem. Am. Acad. vol. 2. 91. On the 27th of November Lifbon fuftained fevere fhocks of earthquake. Courant, April a, 1792. 294 In autumn, bilious remittents affumed, in Philadelphia, the inflammatory diathefis, fo predominant in the laft peftilential conftitution. Dr. Rufh, in his public leaures, mentioned this faa at the time, altho he little fufpecled what effeas that con- ftitution was to produce in fubfequent years. It was found ne- ceffary to bleed from one to three times. In moft cafes, the liver was affeaed with all the fymptoms of Hepatitis. M. S. letter from Dr. Rufh. At this period the peftilential or epidemic conftitution of the atmofphere began to fhow itfelf in the infedious yellow fever. It appeared in New-York, in autumn, along the eaft river, and carried off about 200 perfons. This gave fome alarm, which foon fubfided. It muft be noted that the meafles in 1788, the difeafe which marched in the van of this feries of epidemics, appeared firft in New-York—this was probably the faa alfo in regard to the in- fluenza of. the fucceeding year—and the fcarlatina anginofa at the clofe of 1792. The fcarlatina of 1789 and 91 in Philadel- phia was local, or if it appeared in a few other places, it did not Ipread over the country. All the laft great epidemics have ori- ginated nearly in the fame longitude between Conneaicut and Pennfylvania. It is not to be concluded from this faa that they have been propagated by infeaion from one fpot, as from a cen- ter ; we know this is not the.faa ; the fame difeafes originating in remote places.* But it ferves to fhow that the caufe or prin- ciple of difeafe in the elements is of various force, and will firft fhow its effeas in places where it has the moft ftrength. In the fame fummer of 1791, the peftilential principle began to exhibit its effeas in the increafed malignancy of the tropical fevers. The " unufual, epidemic fever" in Grenada, defcribed by Dr. Chifholm, in the Edinburgh Medical Commentaries for 1793, and which was the occafion of no fmall furprife, was the commencement of that feries of fatal difeafes, which, in fubfe- quent years, made dreadful havoc in the Iflands. This fever became fo violent and infeaious, contrary to the common fever * The mild fcarlatina, the herald of the epidemic, appeared at New- York andatBethlcm in Conneaicut, in 179a, in the fame month. 295 of the tropics, that a labored attempt was made to trace it to fomites from the coaft of Africa. The truth is, the fever waj nothing more than the common fever of the climate, with the fuperadded malignancy derived from the exifting conftitution of the elements. The fame faa took place on the African coaft ; that is, the ufual fevers of the climate became more malignant. This idea isfuggefted by a feries of fimilar events in other cli- mates ; all the difeafes of America, at the fame time, affuming a fimilar augmented violence, and fporadic cafes of malignant fever appearing in all parts of our country. Such has been the faa in all other epidemic periods. To confirm this idea, let it be obferved that in the fame year, when this malignant fever appeared in the African Seas on board of fhips, in Grenada, and in New-York, as well as in fporadic cafes in other parts of America, the plague carried off two or three hundred thoufand people,* in Egypt, and raged in Conftan- tinople with great morulity. In all thefe diftant countries, the fame or fimilar effeas were nearly cotemporary. The plague in Egypt continued into the next year ; but I have no details of its progrefs and termination. The fame general principle was ex- perienced in Great-Britain, and the bills of mortality in London continued to fwell, till the year 1793. The winter of 1791-2 was fomewhat colder than ufual. The month of January was remarkable for fevere weather of three weeks duration. In March a flight earthquake was felt in the middle ftates, but I have no particulars. Courant, March 19, 1792. The fpring months were very rainy in the fouthern ftates and the iflands, which experienced diftreffing inundations. Courant, May 2%, 179s- In the northern ftates there was a period of Angularly cold weather in the beginning of June, occafioned by a dry N. E. wind. Some perfons ufed fires as late as the tenth day of that month. The heat of the following fummer, in general, was not extreme. » Thefe numbers arc to be fufpe&ed of exaggeration, 296 In May and June, a fpecies of locufts appeared in the north- ern parts of the ftate of New-York, which committed ravages among the grain. The wheat-infea continued its ravages, and appeared this year as far fouthward as Elk Ridge in the ftate of Maryland. On Long-Ifland the deftruaion of wheat was great and diftreffing. Courant, June 25, and July 2, 1792. In July happened at Philadelphia a violent tornado ; but the fummer was not diftinguifhed for the number of this fpecies of tempeft. In one inftance, in Vermont, the hail-ftones which fell are faid to have been from 3 to 6 inches in circumference. About this time, a malignant fever began to rage in Charlef- ton, South-Carolina, carrying off the patient in three days, and occafioning a confiderable mortality. Courant, Auguft 6, 1792. In the following winter, Egypt was a prey to famin ; and the ftreets of Cairo were filled with dead bodies. In November 1792 feveral fmart fhocks of earthquake were felt in Perthfhire, a county in Scotland. In Philadelphia appeared an infea in the form of a fly, which generated a fmall worm or caterpillar, that attacked the tree, called Lime Tree, which is there ufed for fhade. From that year to the year 1798, this infea has ravaged thofe trees, and deftroyed fome of them. Juft philofophy will not hefitate to believe the caufe of this phenomenon and of the peftilence fuc- ceeding, to be conneaed. In this year, 1792, commenced that fcarlatina anginofa which became epidemic, with great mortality. I regret that a want of exaa regifters, will not permit me to trace it to its fources with the precifion defireable in all fuch cafes. I am informed that well defined cafes of the difeafe were obferved in New-York, as early as the month of Auguft. But it occafioned no confidera- ble mortality in that city, until the following winter. At Bethlera, in the weftern part of Conneaicut, there were five deaths in this year by the cynanche trachealis. I have not heard of any other inftance. In Auguft, there were feven or eight cafes of the fcarlatina anginofa, but fo mild as not to prove mortal. The reader will note the laft circumftance ; for I am 297 able to prove, that this difeafe in Conneaicut, was progreflive in a remarkable manner, and from the faa, which I believe is not uncommon, will be drawn moft important confequences. The autumn was one of the mildeft ever known. November was fo warm that we fat with open windows, at Hartford, on the 19th of the month. This moderate weather was fucceeded by fevere cold, and Conneaicut river was clofed by ice on the 1 oth of December. The latter part of winter however was not very fevere, except a- week or two in February. On the nth of January 1793 appeared a comet in the con- ftellation of Cepheus. It was feen for the laft time by Mr. Rit- tenhodfe on the 8th of February. Phil. Tranf. Phil. vol. 3. In the courfe of this winter and the fpring fucceeding, the fcarlet fever raged in New-York, with confiderable mortality. It became epidemic alfo in Philadelphia, in the courfe of the fpring months. Catarrh was very prevalent in the northern ftates, at the fame time ; and the fmall-pox by inoculation at Hartford proved un- ufually obftinate and fatal ; indicating an infalubrious ftate of the atmofphere. In February 1793 the fcarlet fever invaded the town of Beth- lem, like " an armed man," fays Mr. Backus, Medical Repofi- tory, vol. 1. 524. He calls the difeafe angina maligna, and it doubtlefs put on the fymptoms of it in many places. It feized almoft every family and child. It abated in May, difappeared in November, and re-appeared in January 1794 with nearly its former violence. Nineteen children died in the firft invafion, and fourteen, in the fecond. We have here diftina marks of progreflion. The difeafe in a mild form appeared in Auguft 1792, then difappeared. In February following, it invaded the town in its worft form. Six months therefore intervened between its precurfor, or mild form, and its invafion with full force. The fame difeafe appeared in the neighboring diftria of coun. try and in diftant parts, in nearly the fame longitude, in the courfe of this year ; but I have not materials for a detail of fafls, O 0 298 I find however, it prevailed in Litchfield in 1793, an<^ was fuppofed to be imported into that town from Vermont. It was alfo very mortal in New-Fairfield, the fame year. I therefore prefume the difeafe to have been very general through the weftern diftrias of Conneaicut, Maffachufetts and Vermont, and to have prevailed as far weftward as Pennfylvania, in this year. Of its progrefs beyond that ftate, I have no information. In September and Oaober of this year, about the time the diftemper fubfided in Bethlem, it began to exhibit appearances of approach, in the maritime towns of Conneaicut. Its precur- fors at New-Haven, as defcribed by Dr. Monfon, a good judge of the fubjea, were" flight influenza, flinging pains in the jaws and limbs, forenefs in the mufcles of the neck, with a flight fever." In November and December following, feveral cafes of ulce- rous fore throat occurred, but they had a favorable iffue, and the fymptoms were not alarming. In January 1794 arrived the crifis of this difeafe ; it put on its malignant fymptoms, and in the courfeof the fix following months, feized more than feven hundred perfons, principally youth, of whom died fifty two. oee Dr. Monfon's account in my Collection, p. 173. Here again is diftinaly marked a regular progreflion of fymp- toms from September to January ; the precurfors being four or five months in advance of the difeafe in its moft violent form. In Hartford, on Conneaicut river, about thirty miles eaft of Litchfield and Bethlem, I had an opportunity to make per- fonal obfervations on the origin and progrefs of this epidemic. I do not know the date of the firft cafe ; but in my own mem- oranda, its appearance in my eldeft daughter, then in the 3d year of her age, is noted under the 12th of May 1793. The attending phyfician informed me, that the difeafe was then epi- demic. Its firft appearance therefore muft have been a week or two earlier. This difeafe was a mild fcarlatina anginofa. The patient had confiderable lever—the paroxifms were daily, and terminated in profufe fweats—there was a partial efflorefceHce of the fkin about the neck and breaft, and fome affeaion of the throat. Its crifis, 299 if I do not mifremember, 'was about the eighth day. Iwasinform- ed that in no cafe, did this difeafe prove mortal, during this in- vafion. The reader will obferve the dates—this mild angina invaded Hartford in April and May, about the time, the feverity of the difeafe began to abate in Bethlem. Nine months after the invafion of this mild angina, that is, in February 1794, this difeafe appeared in Hartford in its formida- ble array, and many children became its viaims. Nothing can prove more clearly that infeaion had no concern in the origin of this diftemper, than this gradual augmentation of its fymptoms. If any faa were neceffary to demonftrate the all- controlling influence of the elements, in the propagation and ter- mination of the difeafe, this progreffign alone would be fufficient. The mild epidemic of May 1793, was the fame fpecies of difeafe with that which was then deftroying life, in the weftern parts of the ftate, and in New-York and Pennfylvania ; but the condition of the atmofphere at Hartford was not, at that time, fitted to give the difeafe its full degree of violence. The fummer feafon perhaps fufpended the operation of the general caufe, by means to us unknown. In February following arrived the crifis of the difeafe. I know not whether other epidemic anginas have been charac- terized by the fame progreflivenefs in the fymptoms. It is not improbable that they have ; and that age after age has paffed away, without noticing the circumftance; a circumftance that throws more light on the origin, caufes and [philofophy of epi- demics, than all the differtations on the fubjea, fince the days of Hippocrates. My own children were affeaed with the mild angina in May. I removed, with my family, to New-York in November 1793, before the fatal angina invaded Hartford, and after it had finiflied its courfe in New-York ; my children efcaped its violence, and probably in confequence of this removal. This was an acciden- tal circumftance in my family, but I fufpea a fimilar removal of children, during the progrefs of that malady, might fave a mul- titude of lives; altho the circumftances of many people will not 3°Q permit them to avail themfelves of the expedient: and in fome cafes probably it would fail of fuccefs. It however deferves con- fideration. The angina had completed its courfe in New-York in 1793 or nearly. It did not invade Bofton till 1795. A re- moval of the children from the atmofphere of Bofton in 17*^5, to an atmofphere where the difeafe had ceafed, would probably have fecured moft of them from an attack. The fummer of 1793 was exceffively hot, after a dry fpring, and produced a great number of violent gufts, with rain and / hail. The autumn was very dry. A fatal dyfentery prevailed n/ in Georgetown, on the Potomak, and in the vicinity, which ■ fwept away many hundreds of the inhabitants. The fame difeafe prevailed in Coventry, in Conneaicut, and killed almoft every perfon whom it feized. A nervous or long fever prevailed in Wethersfield. In fhort, in moft parts of the United States, the peftilential principle exhibited its effeas, in fome form or other, and every where fwelled the bills of mortality. It extended to the Weft-Indie?, and fo violent was the epidemic at Grenada, that the phyficians and inhabitants, unable to account for it, re- ally fuppofed it an import'.! difeafe. The treatife written by Dr. Chifholm to prove it imported, is fatisfaaory evidence to me that the difeafe was an epidemic. The difeafe coirefponds in its prin- cipal charaaer, with the peftilential fevers of this country, many of which are known to be generated in our own climate. In Auguft 1793 commenced in Philadelphia that dreadful peftilence which alarmed the United States, and fpread terror and difmay over that city. The fpring difeafes, which ufhered in this malady, were influenza, fcarlatina and mild bilious re- mittents. See Rufh's Treatife on that fever. Thefe are the moft certain and immediate precurfors of peftilence, in this Country ; and the influenza feems to be fo, in all countries. During this epidemic, the weather was very fultry and dry. A- boutthe 12th of September, fell a meteor betwecr the city and the hofpital. The. number of viaims to this difeafe was 4040. A controverfy arofe among the phyficians in Philadelphia, relative to the origin of the ptague ; one party tracing the dif- eafe,, as they fuppofed, to infeaed veffels from the Weft-Indies j Soi the other afcribing it to exhalations from damaged coffee and filthy ftreets. This controverfy has occafioned an unhappy. fchifm among the medical gentlemen, and the citizens of Phi- ladelphia. / It is greatly to be regretted that gentlemen of the faculty committed themfelves, by prematurely giving pofitive opinions on that important queftion, and thus laying the foundation for permanent evils to the country. It would have been wifer to have inftituted a regular enquiry into hiftorical faas, relating to peftilential difeafes, antecedent to any pofitive decifions on the fubjea. By an account of the deaths in Algiers, kept by Capt. O'Brien, while a prifoner, I perceive that 4893 perfons died in 1793 by the meafles and plague. There was a confiderable increafe of mortality in that year ; and we obferve the meafles and plague prevalent in the fame year—an evidence that on the Barbary coaft, as well as in Europe and America, thefe epidemics are allied. By this account alfo it appears that in 1789 a number of per- fons d ed by the aflhma. It is not probable this was epidemic, and I fufpea by this name was intended catarrh or influenza. As this difeafe was then epidemic in the United States, it would be gratifying to know whether the fame epidemic prevailed on the African coaft, at the fame time. It is remarkable that in the fpring of 1793, when the fcarla- tina anginofa had firft commenced its progrefs in America, it began alfo in England. It appeared firft in the villages about London, and afterwards defcended into the city. Med. Mem, vol. 4. It continued to prevail for feveral years, with different degrees of violence, at different times. See the Monthly Mag- azines. The winter of 1793-4 was milder than ufual in America. The thermometer in New-York, in a northern expofure, defcen- ded no lower than 13 deg. above o, and but twice to that degree. On the 17th of May was a fingularly fevere froft in the northern ftates of America, which deftroyed garden vegetables and the leaves of trees. The wheat, oats and flax in many places turned yellow, and fruit was deftroyed, This froft was preceded by a few remarkable hot days, fuch as we ufually have in June ; and fpeedily followed by a long fe- ries of rains, with eafterly winds. This froft has been fuppofed to kill the canker-worms, which had ravaged the orchards, for fome years preceding. Another opinion is, that a hard froft in April, deftroyed them, juft after they were hatched. A third opinion is, that they had run thro their period of exiftence, and perifhed in a natural way. In Confirmation of which opinion, it is faid they were evidently declining in the preceding year. There is probably truth in both the latter opinions. The fummer of 1794 was, on the whole, not intemperate. We had hot weather, but frequently was the earth refrefhed by fhowers, and cool wefterly winds. The whooping cough pre- vailed in New-York. The fcarlet fever, in the courfe of this year, fpread over Con- neaicut. Its effeas are very apparent in the bills of mortality. It appeared in 1795 in Bofton, in the fpring or early in fum- mer, and continued to prevail in Maffachufetts and New-Hamp- fhire in 1796. Its progrefs from New-York to Maine, about 300 miles or perhaps 400, was run in about four years. It trav- elled therefore about 100 miles in a year. Such alfo was the faa in the preceding period ; as well as in 1735. It fhould be obferved alfo that its direaion, in the two laft epidemic periods, has been oppofite to that of the difeafe of 1735. The latter began in New-Hampfhire and marched to the weftward ; the former began in the middle ftates, and advanced to the eaftward. On the 1 oth of June 1794, the b'ilious plague made its ap- pearance in New-Haven, a feaport in Conneaicut. The perfon firft feized with the difeafe was, the wife of Ifaac Gorham, liv- ing on the wharf, and the nature of her complaint was not un- derftood, nor fufpeaed, till near the time of her death, on the 15th. No fooner was it known that a peftilential fever was in the city, than the inhabitants took the alarm, and direaed an exam- ination to be made into the caufes. On enquiry, the following appeared to be the fources of the difeafe, or were reported to be the probable caufes. S°3 In the beginning of June, Capt. Truman arrived from Mar- tinico, in a floop, which was hauled up by the ftore of Mr. EhV jah Auftin, a few rods from the houfe of Mr. Gorham. This floop was fuppofed to be infefted with the peftilential fever of the Weft-Indies. From this floop was landed a cheft of clothes, which had belonged to a feaman who died with the fever in Martinico ; which cheft was epened and the contents inventoried by Mr. Auftin, in his ftore, in prefence of Capt. Truman, of Henry Hubbard, a clerk in the ftore, and of Polly Gorham, a niece of Ifaac Gorham. Mr. Auftin and his clerk were feized, a few days after the opening of this cheft, (but how many days is not ftated) and died about the 20th of June. Polly Gorham was feized on the 12th and died on the 17th of June. Thefe circumftances appeared to the people at that time, to be clear and deciCve evidence of the importation of the fomites of the difeafe; and efpecially the fad, that Mr. Auftin and his clerk were attacked with the fymptoms, nearly at the fame time. This acquiefcence in an opinion fb important to fociety and truth, renders it neceffary to ftate the refult of more careful enquiries. In the firft place, the opinion that the floop could communi- cate the infedion, is unfounded ; for it does not appear that any perfon, ill with yellow fever, had been on board—there cer- tainly had not been any fick on board, after her leaving Martin* ico. The floop was taken by the Britifh troops, when they took that ifland, and lay in port fome weeks, unoccupied ; until Capt. Truman had an opportunity to purchafe her. In the mean time, fome of the crew, to keep themfelves employed and procure bread, went in the bufinefs of droging ; that is, tranf- porting goods from place to place. One of them died with the fever, but on fhore, and he had not been on board of the floop, after his illnefs. On the paffage home, the feamen. were all in good health. Then, is therefore not the leaft ground to fuppofe the floop contained any infeaion, and no part of her cargo was fuppofed to be in a bad ftate. The external parts of a veffel or houfe canno'. retain or communicate infeaion. Secondly. As to the cheft of clothes, it is probable it con- tained no infedion from difeafed perfons; for by the affidavit of 4°4 Capt. Truman, taken before Alderman Furman of New-York, at the requeft of Dr. Baily, the Health Officer of that port, which affidavit I have confulted, it appears that the clothing, worn by the feaman who owned the cheft and died at Martinico, was all wrapped in his blanket with his body and buried. As Capt. Truman is a man of good charaaer and has made his affi- davit, four years fince the difeafe at New-Haven, when all ap- prehenfions of injury from declaring the truth, have fubfided, there feems to be no reafon to queftion the faa. But as men, who have not attended to the great operations of nature in producing epidemic difeafes, naturally look for the caufes among vifible and tangible fubftances, they ftill found a refource in a Britifh regimental coat, which was in the cheft, and which, it was fuppofed, might have belonged to a foldier who might have died of the yellow fever. In confequence of thefe fufpicions, the contents of the cheft were all burnt. On examination it appears that the coat was new—and the mate of the floop has fworn that he law the coat plundered by the feaman from a bale of goods, and he believes it had never been worn. It was taken by the feaman in the bufinefs of drog- ing, from among the packages of clothing fent by the Britifh government for the ufe of the troops. But had we no fuch evi- dence, common fenfe might inform us, that a man, laboring un- der a fever in the fultry climate of the Weft-Indies, would not wear his regimentals. In the cheft therefore, as in the floop, we can find no infec- tion of yellow fever. If Mr. Auftin and his clerk received the feeds of difeafe from the clothing in the cheft, as it is poffible they did, the fources of the difeafe muft have been the fetid effluvia of dirty clothes, which had been kept a long time, clofe packed in a cheft, in a fultry climate. It is not neceffary to fup- pofe the clothes to have been worn by a difeafed perfon. The fweat and filth from a body in health, if confined in the hot fea- fon, will ferment and produce a poifon injurious to health, and produaive of yellow fever or other difeafe.* " It is a well authenticated fact, that Mr. Daniel Phenix, treafurer of the city of New-York, and his fon*, were infc&ed with a violent yellow ftver, by means of the fetid effluvia from packages of Lulls, of 3°5 But as feme reports have been circulated, in contradidion of the teftimony of Capt. Truman, and as there is a poflibility that he might have miftaken the faas, I lay out of this queftion all the evidence refpeaing the floop. For whether the trunk con* tained infeded clothes or not, is wholly immaterial; and with« out any reference to that point, the evidence that the fever in NeW-Haven did not fpring from any imported fource, is complete. Mr. Auftin went on bufinefs to New-York, was feized with fever and died. His body was conveyed in a floop to New- Haven, and buried. It is an agreed point, that no friend, nurfe or other perfon took the fever from him. Mr. Hubbard went on bufinefs to Derby, ten miles diftant, was taken ill and died. His body was carried to New-Haven, and buried. It is agreed that no perfon took the difeafe from him. It is not known that Polly Gorham was ever near the trunk of clothing—the report of her being prefent refts on the ftory of a child. But if fhe was, it makes no difference, for no per- fon who attended her was affeded, except her mother, who had a flight fever. She lived and was ill, a mile from the wharfi and no perfon in that neighborhood was afterwards affeaed. In fhort, it is not pretended that the infeaion proceeded from either of thefe perfons—the only perfons who could poflibly have taken the difeafe from the trunk of clothing. It is admitted on all hands that the infeaion muft have pro- ceeded from the houfe of Ifaac Gorham. Now it happens that Mrs. Gorham who was firft feized and five days before Mr. Auf- tin and his clerk, had never been near the trunk of clothing, nor v/as an article of clothing from the floop carried into the houfe, For this affertion, I have the authority of Mr. Gorham himfelf, who is' admitted to be a man of veracity. Had the origin and phenomena of epidemic difeafes ever been underftood, the people of New-Haven would have forefeen, with credit, which had been returned into the treafury, after being long ufed, palTing through dirty, fweaty hands, and then being clofe pack-. ed for fome weeks, in a hot feafon. The fact is related to me by Mr. Phenix himfelf. The attack in the firfl cafe, was fevere; and on a fubfequent occafion, a fecond attack paffed off with a naufe-a, P P 3°6 a good degree of certainty, that they could not efcape peftilence. This will appear from the following fads. In the winter and fpring of 1794, the fcarlatina anginofa pre- vailed generally in New-Haven and the neighboring towns ; manifefting a highly peftilential condition of the elements. One cafe of bilious fever, attended with a vomiting of black matter, occurred as early as the laft week in March. For many months preceding the invafion of the fever, the oyf- ters, on the coaft of Connedieut, were in a very fickly ftate. Many people can teftify to the truth of this fad ; but I have an account of it recorded at the time by the late Prefident Stiles. In a letter to his fon-in-law, the Rev. Mr. Holmes, of Cam- bridge in Maffachufetts, dated Sept. 25, 1794, he writes, that for twelve months paft he had eaten very few oyfters, as they were difeafed, poor and dropfical. He remarked this of the oyfters from New-York to Bofton. Thofe caught on the fhores of Branford, Killingworth, and at Blue-Point on the fouth fide of Long-Ifland, were intolerable. At the date of the letter they were recovering and becoming more palatable. This is a ftriking proof of the derangement of the elements. \ Further evidence of this faa was furnifhed by the multitudes of caterpillars which overran the city of New-Haven, in the fum- mer of 1794.* In fuch numbers were thefe infeas, that they almoft covered the trees, fences and houfes to the tops of chimneys. The preceding hiftory furnifhes many inftances of this phenome- non, preceding and accompanying peftilence. Had thefe phenomena been underftood, the people of New- Haven would have had no occafion to appoint a committee to ex- amin into the caufes of the fever. It was hardly poffible, in the nature of things, that the human race fhould efcape the calamity of epidemic difeafes, under the operation of caufes fo general and powerful. But thefe were not all. Mr. Gorham, whofe family firft fuf- fered by the fever, had, in the month preceding the invafion, cleaned a gr,pat number of fliad, upon the wharf by his door, * Some perfons fay, this was in 1793, but it is not materiaL 3°7 and thrown the garbage, to the amount of a cart load perhaps, in. to the dock. The alternate wafhing of the tide, and aaion of a hot fun, had rendered the putrefaaion of this mafs of filth extremely ra- pid ; and there being no current to remove it, the ftench be- came intolerable. On the other fide of the wharf, a few rods diftant, a boat load of clams had been depofited on the mud, that the water, during the flux of the tide, might preferve them ; but a great part of them were foon fpoiled, and added to the fetor of the atmofphere. To complete the lift of nuifances, fome barrels of damaged pickled cod-fifh had been thrown from a ftore into the dock, and the whole was left uncovered during the recefs of the tide. So noifome was the air of the place, for fometime before the fever appeared, that the proprietor of the wharf defifted from his ufual morning vifits before breakfaft. For all thefe faas I have the declarations of the perfons concerned and eye witneffes. The putrefaaion of flefh, from thirty years obfervations, I canteftify, will not always produce difeafe. But in a peftilential ftate of air, the diffoluiion of flefh is unufually rapid, and the acid evolved, peculiarly noxious. In fuch circumftances, putref- cent fubftances of all kinds appear to be powerful auxiliary cau- fes of difeafe. The condition of the elements accelerates putre- faaion, and that putrefaaion in turn increafes the deleteribus quality of the air.* Under the operation of fo many caufes of difeafe, inftead of being furprifed at the appearance of a peftilential fever, we are rather to wonder that its ravages were not more extenfive. That the putrefaaion of the fifh was an exciting caufe of the fever in New-Haven, is probable from the early appearance of it in fummer. The firft cafes occurred about the ioth of June, which is earlier than the epidemic peftilence of America ufually occurs ; and which indicates the exiftence of ftrong local caufes. What further confirms this opinion, is, that after a few weeks * 1 may add to thefe caufes of the fever, the water pf the well ufed by the people living on the wharf, which happened at that time to be covered over with dead rats in a ftate of putrefaaion. This, was dif- coverd by the offenlivenefs of the water. 3o5 the diftemper v/as nearly or wholly extina. In July died only" three perfons, and for about two weeks, no new cafe occurredt But in Auguft, the ufual time of the appearance of this difeafe in this part of America, it broke out with frefti violence. It is probable therefore that the morbid local caufes induced the fever in one fmall fpot, before the proper feafon for it to prevail. Thefe caufes being gradually extingi.iftied by the tides and a hot fun, the difeafe fubfided, until the ufual feafon for fuch fevers. The fame took place in New-York in 1795—in 1796—and 1798. That the plague in New-Haven was the effea of a condition of the elements united with local caufes, is proved by fubfequent events. In the following year, a malignant dyfentery originated / and prevailed in New-Haven, deftroying more lives than the bil- J ious plague of 1794. This difeafe is acknowledged by able phyr ^^ficians to be of the fame fpecies as the yellow fever. See Lind on that point, and Rufh's Works vol. 5. 5, where it is ftated, on the authority of Dr. Woodhoufe, tlrat feveral perfons took the yellow fever from foldiers, laboring under the dyfentery. It is Well known alfo that an epidemic yellow fever has been converted^ by a fudden change of weather, into an epidemic dyfentery, and t_ iiicc verfa ; as at Baltimore in 1797. It is alfo true that the yel- low fever in autumn paffes off in dyfentery, as in New-London in 1798. The fame is at times true of the plague in Afia. This difeafe in 1795, as well as a fimilar dyfentery in Derby in 1794, demonftrated the deleterious condition of the elements in that region or vicinity. If further evidence was neceffary, we have it in the bad ftate of the water in fome of the wells in New-Haven, during the preva- lence of thefe difeafes, in which, one of the phyficians of the city has informed me, were animalcules vifible to the naked eye. This fad correfponds with what occured in Athens, during the plague, where the badnefs of the water, it is fuppofed, fed the people to afcribe the difeafe to the poifoning of the wells by the Lacede- monians. A fimilar fad probably led the Germans, in 1349, to fufped the Jews had poifoned the wells, arid on fufpicion alone to maffacre them without mercy. This ftate of the water, and the ficknefs of the oyfters alone decide the point, thatthe prints pal fources of the epidemics of 1794 and 5, were in the elements, 369 It has been afferted that no perfon in New-Haven was aBedec! by the fever, without intercourfe with the fick or with infeded clothing. On careful enquiry, I find this is not true. Several perfons were affeded who were not in the rooms, nor even in the houfes of the fick, and who could not be expofed, other- ways than by pafling along the ftreets. But fuch perfons Could not take the fever from the effluvia of the difeafed. Men who fuppofe this, are unacquainted with the powers of infedion. Dr. Chifholm ftates exprefsly that the infedion of that difeafe in Grenada never exceeded ten feet ; that it was eafy to avoid it, and many who lived in the houfes of the difeafed, efcaped. Med. Repof. vol. 2. 288. Dr. Lind, the ableft writer on the fubjed, who fpent his whole life in jails and hofpitals, has ad- vanced the fame dodrin. A great number of fick in a narrow clofe built ftreet, may render the air of it infedious, but a few difeafed perfons in the wide ftreets of New-Haven could not produce this effed. In general however the difeafe in this place was propagated by infedion ; the pollution of the atmof- phere being confined to a fmall diftrid on and near the wharf, on low ground, to the leeward of the putrid fubftances before mentioned, and near the creek. But there is one fad that will decide the queftion relative' to the origin of the peftilential fever in New Haven, and every other place. It is ftated by the phyficians that all other difeafes yielded to this fever. After it appeared in June, the fcarlatina fubfided, and " in September, when the fever was moft preva- lent, the inhabitants in general were almoft entirely free from every other complaint." See Dr. Monfon's ascount of the fever, in my Collection, p. 178. Here we have an infallible criterion by which to determin whether a difeafe is an epidemic of the place, or introduced and propagated folely by infedion. A difeafe of mere infedion can never extinguifh other difeafes of the place. The fmall-pox introduced by variolous matter, and communicated to every fam- ily would not abforb a dyfentery or fcarlet fever prevailing in the fame place ; every hofpital will demonftrate this principle. A difeafe of mere infedion would not affed another difeafe evea 3to in the next houfe. Every difeafe that extinguifh.es another dif- eafe current in a town, is an epidemic originating in that place. It not only proves that the atmofphere will produce that diftem- per, but it proves that it will produce no other. On this princi- ple I will reft the queftion, as it regards not only the fever .in New-Haven, but every peftilence that ever exifted. The fummer of 1794 was, in moft places, lefs fickly than in 1793 and 1795; yet the fcarlatina extended its ravages over Connedicut, and Philadelphia and New-York experienced, the predominant epidemic conftitution. In Philadelphia died from 70 to 100 perfons of the bilious plague ; in New-York twenty or thirty cafes of the fame difeafe indicated the fame condition of the atmofphere. It was the general opinion in New-York, that the city was remarkably healthy ; but this opinion, fo flat- tering to the people, was a fallacy. The bills of mortality were higher than in healthy years, and this augmented mortality was a prelude to the epidemic of the fucceeding year. On the 15th of June was a great eruption of Vefuvius, nearly equal to that of 1779. The lava ran down the mountain on the weft and extended to the fea, overwhelming the town of Tome del Greco. See Univerfal Mag. for Aug. 1795- In this year the bilious peftilence. prevailed in Baltimore. No fuggeftion has been made that it was imported, and the phyfi- cians and inhabitants feem to admit the difeafe to have been on- ly a more malignant form of the ordinary autumnal remittent. In the fucceeding winter, the epidemic of the fummer and autumn changed, in Philadelphia, into the form of catarrh or pleurify, and in many cafes, was auended with delirium and mania. See Rufh on this fubjed. Peftilential epidemics, or rather the ftate of the atmofphere which produces them, ufually affeds the brain, in a moft fenfi- ble degree. This is obvious from the vertigo, fo frequent during fickly periods ; pains in the head, dizzinefs and nervous debility often complained of by ftudious men. In fome periods, this affedion of the brain has appeared in epidemic madnefs. Sec the years 1355 j 1373 and 4. 3" A few cafes of a diforder of this fpecies appeared in New- Haven and its vicinity in the winter after the peftilence. The patient was feized with a violent pain in the head, between the Os frontis and the Coronal Sutures, which was periodical, com- mencing about 11 o'clock A. M. and increafing till 2 P. M. In fome cafes, the paroxifm was accompanied with delirium ; but the pain was limited to the head, and unattended with fever. Bleeding, purging and opium produced no alleviation; but a bKfter on the forehead or temple, foon relieved the patient, and effeded a cure. This account is taken from Dr. Hotchkus, the attending phyfician. The winter of 1794-5 was very cold in Europe, and in January 1795, the French troops marched into Amfterdam, over the rivers and canals, on the ice. This feverity was to be expeded from the great eruption of Vefuvius in the preceding fummer. The catarrh was epidemic in January and February, in the Britifh channel fleet. In one fhip it affumed the fymptoms of a pure typhus. Trotter's Med. Naut. p. ,366. In America, the fame winter was milder than ufual. Per- fons walked on the battery at New-York, for pleafure, on Chriftmas day, with no covering but their ordinary autumnal clothes ; and veffels failed up the Hudfon and Connecticut till January. In the latter part of the winter, we had fome cold weather, and a cool late fpring. About the 20th of July, began a feries of hot, damp, rainy weather, with light foutherly winds ; a feafon anfwering to the defcription which Hippocrates has given of a peftilential confti- tution. Heavy rains were followed by a humid, clofe, fultry air; no thunder and lightning ; no north-wefterly winds to cool and refrefh the fainting bodies of men. For many weeks the atmofphere was fo loaded with vapor, that no eledricity could be excited with the beft inftruments. Fruit perifhed on the trees and fell half rotten and covered with mold. Sound potatoes from the market perifhed in my cellar in thirty-fix hours. Cab- bages-rotted off, between the head and the ftalk, as they ftood 312 in gardens. The moifture penetrated into the inmoft reeef. fes of defies and bureaus, covering books, papers and clothes with mold, under two locks. The walls of houfes, and the paper of inner apartments became white with mold and required fcraping. This ftate of the air produced alfo mufketoes without number; v/hile flies difappeared. It is obfervable that thefe two kinds of infeds thrive in different conditions of the air— flies in a hot, dry air ; mufketoes, in a hot, moift air. It is neceffary here to corred a miftake of Dr. Currie on bil- ious fevers, page 12, where he mentions the years 1795 and 7 as " wetter and cooler than many preceding feafons." The truth is, thelatter part of thefummer of 1795, was on an average three degrees by Farenheit, warmer than the weather had been in the ten preceding years. See a letter from Profeffor Kemp in Dr. Bailey on yellow fever, p. 54. In the courfe of my life, I never experienced a ftate of air fo debilitating and un- friendly to animal fpirits, as the month of Auguft 1795. The effeds of it are very vifible in the bill of mortality for that year in Philadelphia, which contains double the ufual number of deaths. In July of this year appeared the bilious plague in New-York. The firft cafe that excited public attention was that of Dr. Treat, the Health Officer of the port, who fell a viaim, on the 29th of the month. His difeafe has been afcribed by fome perfons, to infedion taken on board a veffel from the Weft-Indies, the brig Zepher in which a perfon died, whom Dr. Treat affifted in burying. But it is not probable, that this was a juft opinion ; as many other perfons vifited the fame veffel, and the wardens of the port were on board, while a part of her cargo, fome damaged coffee, was thrown into the ftream, without the leaft inconvenience to their health. The plethoric habit of Dr. Treat, and his great fatigue in an open boat and in a burning fun, are fufneient to account for his difeafe. But admitting him to have taken his difeafe from the fomes of a fick or dead perfon, or from the foulnefs of the brig, the fad does not in the leaft aid the advocates of infeaion, for no per- £>n, nurfe, attendant or vifitor, received the diftemper from him. 3l3 nor did the difeafe prevail, in the ftreet where he died, during the fubfequent feafon. It was faid that three or four feamen, belonging to the fhip William, were feized with the diftemper in confequence of vifit- ing the brig Zepher. But on enquiry, it was found, that thefe men only came along fide of the brig and purchafed fome fruit. To fuppofe thefe men fhould all take a difeafe from the brig, when two or three wardens of the port, who were fome hours on board, while a damaged cargo was difcharged, efcaped without the leaft affeaion, is ridiculous. But what cuts fhort all controverfy on this fubjea, is, that fourteen days at leaft before the death of Dr. Treat, a man in the hofpital died of a fimilar fever ; and the late Dr. Pitt Smith, in- formed me in the autumn of 1795, that he vifited another patient aUackfmith, with a fimilar difeafe, early in July. In fad then, the difeafe was in New-York before the arrival of the fuppofed infeded veffels ; and the cafes which occurred early in July, were precurfors of the epidemic which was to follow. It muft alfo be obferved that the difeafe in New-York never fpread over the whole city. It ran along the low ftreets on the Eaft river, in what was formerly the fwamp and in the narrow alleys. The high grounds in the center of the city, and the wef- tern fide of the ifland, were healthy as ufual; and the difeafe, when carried from the infedgd ftreets, upon the elevated parts of the city, exhibited no contagion, but difappeared.—A fmall part only of the citizens fled ; moft of them remained, and pur- fued their occupations, in the greateft part of the city, with per- fed fafety. The deaths were about f.-ven hundred and thirty ; among which at leaft five hundred were foreigners, moft of whom had recently arrived from Scotland and Ireland.* The mortal- ity in New-York was moftly owing to this influx of foreigners, not feafoned to our climate. This fever in New-York was preceded in fpring by epidemic meafles, which difappeared totally during the three months, wheq , ♦ Four hundred and fixty two belonged to the Catholic Congrega- tion under the Rtv. Mr. O'Brien, moft of whom had been to inert a time in the country, that he did not know them, 0.9 3M the fever was the ruling difeafe, and re-appeared in November— a decifive evidence that the fever was produced and controlled by the fame caufe, as the meafles. In this year alfo appeared the fame difeafe at a landing, called Mill-river four miles from Fairfield, in Connedicut, and about fixty miles from New-York—a fmall village, near the water. It was reported that this diftemper was propagated at Mill-river, by infeded perfons from New-York. I have taken pains to en- quire carefully of both the attending phyficians and the clergy- men, who vifited the fick, who all agree, that one man from New-York had died of the fever in the village, that fummer, and he was dead, three weeks before, Mr. Tharp, the firft man feiz- ed, v/as taken ill. The difeafe affeded others of his family, but fpread no fur- ther ; and the gentlemen abovementioned do not believe it to have been derived from imported infedion. The bilious remittent fever, is annually the difeafe of autumn in fome parts of the fouthern ftates ; and ftrangers, vifiting that country from the Delaware to Florida, in the hot feafon run the hazard of a fever. Drs. Taylor and Hansford, two old praditioners in Norfolk, Virginia, fpeaking of the yellow fever Oi 1795, fay, " The fame fever, with all its malignant and uncontrollable fymptoms, occurs every year, in fcattered in- ftances, and about the fame feafon." See my Collection on Bilious Fevers, p. 151. But during peftilential periods, this difeafe in that unhealthy country, takes a wider fpread, and becomes infedious. In 1795 this was the cafe at Norfolk—a town that is fituated on low flat land, a few feet only above high-water, and fubjed to autumnal fevers. The difeafe prevailed moft in the narrow ftreets and poor fmall houfes, and was moft fatal to ftrangers. Two remarkable fads occurred there and are related in the account laft cited, to prove thatthe difeafe was occafioned folely by a general ftate of the atmofphere in and about the town, without a dependence on infedion. The firft is, that traders who vifited the port, altho they were not known to have had in- tercourfe with the fick, took the difeafe and died on their re- turn into the country. But a more remarkable fad is, that the 3*5 feamen of a fhip from Liverpool, which did not approach near- er than five miles diftance from the town, and which had no communication with the fhore, except by means of the health- boat, were almoft all attacked with the difeafe, in ten days after their arrival. This was late in the feafon, and when the difeafe had nearly difappeared in town. In the year 1794 feveral cafes of the fame difeafe had occur- red in Norfolk. In 1797 the difeafe was again frequent. In 1795 and 7, the difeafe was fuppofed to have been augmented by the great rains and floods which had preceded, and which had brought down the river and fpread on the fhores, large quan- tities of vegetable fubftances. The extreme unhealthinefs of the fummer of 1795, was man- ifefted by unufual mortality in various other parts of the country. On the level plains of Duchefs county is New-York ftate, pre- vailed a mortal dyfentery and typhus fever. At Coxfakie on the weft of the Hudfon, raged fimilar difeafes with fatal effeds. In fome weftern parts of the ftate, near the marfhes which border the waters of the country, a malignant bilious fever was more terribly fatal, than the fever in New-York. In Sheffield, a weftern townfhip of Maffachufetts, near two large ponds which form marfhy grounds, bilious fevers, which had not been known there for many years, before, prevailed and in fome cafes were mortal. See Dr. Buel's account of thefe difeafes, in my Collection, p. 53. In that town, the progreffivenefs of the morbid principle of this peftilential period, was clearly difcoverable. Many cafes of intermittents occurred in 1793 ; and a few inftances of bil- ious remittents- This was during the plague in Philadelphia. In 1794, early in fpring, inflammatory difeafes of the pneumo- nic kind, were unufually frequent. Thefe were fucceeded by intermittents, which were more frequent than in the preceding year. In July, the bilious remittent appeared, and 80 inhabi- tants out of 150, who lived within a mile and a half of the fouth pond, wereaffeded. In 1795, of 200 inhabitants within three fourths of a mile diftant from the north pond, 150 were affeded with the fame difeafe—but few died. 3i6 In 1796, the dyfentery, which had not appeared in many preceding years, began its attacks on children, and not long af- t«r adults were taken either with the fame difeafe or with the bil- ious" remittent. Of one hundred families living within a mile and a half of one of the ponds, not ten efcaped ficknefs—more than half of the inhabitants were, in the courfe of the feafon, attacked with one or other of the above mentioned difeafes. Of 150 perfons who lived neareft to the pond, not ten efcaped. The deaths by thefe difeafes were forty-four. Here then was a regular increafe of malignancy in the autumnal difeafis, from in- termittents, to the worft form of dyfentery and bilious remittent. Med. Repof. vol. 1. 456. In the preceding period, great mortality prevailed among the geefe in fome parts of our country; and in the year 1796, a fimilar mortality among other fowls. I have not been able to ob- tain a particular defcription of the fymptoms, but it was obferved the tranfition from apparent health to death, was very rapid. In 1796 the meafles which commenced in New-York in 1795 Was epidemic in Conneaicut; and unufually prevalent in London. In 1796 alfo the bilious plague again appeared in New-York, but in a different quarter of the city from that which was princi- pally affeaed, the year preceding. In 1795, it began and was moft general in the north-eaftern part—in 1796, in the fouth- weftern part, near the battery ; and in both fummers, its feat was along the wharves on the Eaft river, and in the adjoining ftreets and alleys. All this part of the city is a level, formed by extending the land and wharves into the Eaft river. The land is of courfe loofe and porous, admitting, in many places, the wa- ter of the fea into the cellars of the houfes ; fome of which are penetrated, on every flux of the tide. Thefe artificial ftreefs, Front and Water ftreets, are not eafily wafhed clean, on account of their level pofition, and they receive the filth wafhed from the higher grounds of the city. To thefe ftreets, and fimilar ones in the fwamp on the north-eaft, was the malignant diftemper principally limited. In 1796 a new wharf below Exchange flip, which had been timbered the preceding autumn, and left unfilled, had become a 3*7 refervoir for all kinds of putrid, filthy fubftances, and was fup- pofed to be a powerful caufe of difeafe. Befides, the quarter in which the difeafe raged this year, is al- moft wholly covered with old wooden houfes, and many of them, built before the railing and paving of the ftreet, have their lower floors two or three feet below the furface of the pavements. In this diftria appeared the yellow fever in June ; but a feries of rainy weather and cool wefterly winds, fufpended its aaion, in the beginning of July. Succeeding hot weather renewed it, and in the limits above defcribed, extending about forty or fifty rods, about feventy perfons fell viaims. The other parts of the city remained in the ufual autumnal ftate of health, with only a few fcattering cafes of the plague. At Wilmington, North Carolina, prevailed a fimilar difeafe. It was preceded by the dyfentery, in July, after a very wet fpring. When the bilioiars fever commenced in Auguft, the dyfentery declined, and thofe who had been affeaed with it ef- caped the fever. About one hundred and fifty deaths, by thefe two forms of difeafe, occurred in 130 families. Different opin- ions were entertained about the origin of the fever ; but the phy- fician who gives this account has no doubts of its domeftic origin. He informs us further that a few cafes, in that town, occur annu- ally, which affume all the fymptoms of a violent yellow fever. Med. Repof. vol. 2.153. Dr. Roflet's letter. In this year, the difeafe ocqafioned a confiderable mortality in Charlefton, South-Carolina, and in Newburyport, in Maffachu- fetts. It appeared in Bofton alfo, but was not general nor fevere. In Charlefton, it fucceeded one of the moft deftruaive fires, ever known in that city ; and was in part afcribed to the ftagnant water which accumulated in the open cellars. In Newburyport, there was no plaufible pretext for afcribing the difeafe to imported infeaion ; and the general belief was, that the immediate exciting caufe, was, the remains of large quanti- ties of fifh which had been left to corrupt on the wharf, near which the diftemper originated, and which occafioned an intolerable ftench. But in that town, a previous increafe of mortality indi- cated a fickly ftate of the elements; as in all other places, where 3l8 the peftilence has made its appearance. In none of^the northern ftates, which are ufually healthy, has the bilious plague occurred without other difeafes for precurfors.—The difeafe in Newbury- port was confined to a low ftreet or two, and when carried upon the high grounds, it exhibited little or no infedion, but difap- peared with the death or recovery of the patient. M. S. Letter from Nicholas Pike, Efq. In Bofton, the difeafe fpread only in a fmall part of the town, adjoining the water. The phyficians were unanimoufly of opin- ion, that it was not occafioned by any fomites from infeaed arti- cles imported, but generated in the town. See Dr. Warren's Letter in the Medical Repofitory, vol. i. p. 136. The peftilential ftate of the elements was ftrongly marked, this year, by the poornefs of the fhad brought to market in New York. Thefe were all thin, lean and fmall ; and for this reafon, I pur- chafed none for my own ufe, during the feafon. Other perfons obferved the faa ; and I am fince informed that fuch of thofe fifh as were pickled, perifhed in defiance of all human care topre- ferve them. The fame ftate of the fhad was obferved in Con- neaicut. Some cafes of yellow fever occurred in Philadelphia in 1796 ; catarrh was frequent in the winter, followed by meafles of a moft inflammatory nature. A remarkable halo appeared on the 25th' of July. Rufh, vol. 5. 9. It has been already obferved that the winter of 1795, was remarkably fevere in Europe. In America the fame winter was as mild as ufual. But in the fummer and autumn of 1796, the northern ftates experienced a moft fevere drouth. The following winter was very fevere ; the cold exceeding what is ufual, and being of long duration. The fummer of 1797 was cool and wet. The winter of 1797-8 was fevere— and the cold of very long duration. It commenced early in No- vember and continued till March. The Hudfon and Conneai- cut were clofed in November ; a very rare occurrence. For feveral weeks in November and December, the wind, without much fnow on the earth along the Atlantic coaft, was from the liorth-weft and intenfely dry and cold. 3l9 In Auguft 1797 appeared a comet, which, according to cal- culations of aftronomers, paffed near the earth, altho it was of fmall apparent magnitude, and feen by few people. The influence of this fpecies of bodies in occafioning great tides, and violent ftorms, has been already mentioned, and of that influence, in the prefent inftance, I was a witnefs. In 1797 my refidence was, as it had been the preceding year, on a height of York Ifland near Corker's Hook to the northward of which is a flat, which is never covered with water by a common tide, but is overfpread by fpring tides, or any unufual fwell in confequence of eafterly winds. I obferved, as early as the laft week in May, high tides were unufually frequent and the fwell extraordinary. In the city of New-York, the fame faa was obfervable; and the inhabitants about Beekman flip will recol- Iea how often the wharves and ftreet were covered with water. Thefe tides were not to be accounted for, on any known prin- ciples of lunar influence, and I frequently mentioned the phe- nomenon to my friends, but without fufpeaing the caufe. The fame phenomenon was noticed at other places. In Norfolk, the epidemic fever was, in part, afcribed to unufual tides; as I was afterwards informed. On the Delaware, the overflowing of the low lands, below Philadelphia, was extraordinary, and fome phyficians afcribe to this caufe the yellow fever, which fwept away moft of a family by the name of Whitall. I was lately mentioning thefe events to a refpedable gentleman in Stamford,* who inftantly recolleaed a faa which confirms the foregoing account. He remarked that the common praaice in that town, is to mow the fait meadows, at the quadratures of the moon, on account of fmall tides ; but in 1797, the calcula- tions failed, and the people were much troubled to colled their hay, on account of high tides—a circumftance that was very furprifing to him at the time, but he did not advert to the prob- able caufe. This was in Auguft ; about the time that the comet was firft obferved. The. faa then of the influence of comets, in raifing the waters of the ocean, is well eftablifhed ; and the * The Hon. John Davenport, now reprefentative in Congrefs. 32° appearance of a comet in autumn explained the phenomena of the tides to my fatisfaaien. The influence of comets in augmenting tempefts is equally certain and remarkable. On the 19th of Auguft, a ftorm and whirlwind in South Pruffia tore up forefts carried trees along like fheaves of wheat, and levelled feveral villages. In Rome and Naples happened a moft extraordinary tempeft on the 25th of September, fuch as the oldeft man eould not re- colka. It took up men and carried them fome diftance. The aftronomers were confulted and they afcribed it to the approxi- mation of the comet. A ftorm of hail in the province of Macconnois, in France, and on the borders of Burgundy, deftroyed the vines and fruits of the earth in thirty-four villages. In the appropriations made afterwards by the councils of France, four millions were granted to repair the loffes by hail, inundations and other difafters. On the 7th of September, a confiderable fhock of earthquake was felt in the Weftern Pyrenees. On the 28th of the month was a volcanic eruption in Guadaloupe ; and many earthquakes Occurred during the autumn, In England, the fummer was fo rainy and wet, as to injure the corn and threaten the inhabitants with fcarcity. It would require pages to relate all the accidents by floods in Great-Brit- ain from Auguft to the clofe of the year. During the autumnal months, the Black fea alfo was unufu- ally tempeftuous, and the lofs of fhipping alarmed Conftantino- ple, with apprehenfions of a fcarcity of provifions. In February, 1797, South-America was terribly convulfed. Quito and the neighboring provinces fuffered, by the deftruaion of almoft every houfe. Mountains were detached from their ftations and relied againft each other, burying villages in ruin. Volcanoes emitted fire, lava, and rivers of water. It is faid, that 40,000 inhabitants periflied. On the 1 ith of January 1798 a fhock of earthquake was felt in Lancafter, Pennfylvania, and the neighboring towns, during which appeared to iffue from the earth a, flame or hlaze^ like the burning of a chimney, 321 Ih this month, the . fevere cold reached the Weft-Indies* and froft appeared,, for feveral mornings, on the windows in Port Royal Parifh, in Jamaica. A fmall earthquake was felt there in January. Royal Gazette, Jan. 2% 1798. In February 1797 alfo violent earthquakes were experienced on the weftern coaft of Sumatra, in the Eaft-Indies. This year, 1797, was remarkable for other fingular phenom- ena in Europe and America. In England a peftilence among cats fwept away thofe animals by thoufands. It feems that this difeafe began as early as April, and fucceeded an epidemic catarrh among the human race. The fame cat-diftemper was afterwards epidemic in France. A fb* ciety at Montpelier inftituted an enquiry into this remarkable phenomenon. The cat-diftemper appeared in Philadelphia, as early as June, and proceeded northward and eaftward, like the catarrh of 1789. In Auguft it was very fatal in New-York, and in the courfe of the fummer and autumn, it fpread deftruaion among thofe ani- mals over the northern ftates. In Auguft, dead fifh, in great numbers, were feen to float down James' river, in Virginia, for many days in fucceffion. Canine madnefs, during the fame year, was unufually epidemic and attended with fatal effeas, of which full accounts may be feen in the firft volume of the Medical Repofitory. Thefe phenomena indicate an unhealthy ftate of the elements. But it is a remarkable faa that, in fome places and feafons, the principal force of the epidemic conftitution feems to be fpent on one fpecies of animals, while others are exempt. Thus in Eng- land, the catarrh, which had affeaed mankind in 1797, ceafed, before the epidemic feized the cats. In America, the northern ftates, with the exception of a few places, were remarkably healthy, in 1797, while cats died in multitudes. And it is a frequent occurrence in Europe, that while the plague or fome other malignant difeafe is affliaing the human race in one coun< try ; in another country, mankind will efcape, and a moft terri- ble mortality will occur among cattle, horfes or fheep, R x 322 In 1797 the bills of mortality in the northern ftates, which had been fwelled very high by angina and malignant fevers, fell nearly to the ftandard of health. There are a few exceptions. The plague appeared in Philadelphia, Baltimore, Norfolk and Charlefton. In the two latter cities, it is confidered, as the ufual autumnal fever, with aggravated fymptoms, from fea- fon or other local or temporary caufes. In Baltimore, the difeafe appeared firft in the form of a com- mon remittent, but increafed in malignancy till late in autumn and became infeaious. The hiftory of this epidemic is minutely ftated by the magiftracy of Baltimore, and is too interefting to be paffed with a flight notice. The following is a correa ab- ftraa of the ftatement made and publifhed by authority. The commiflioners ftate to the mayor of the city; That the firft appearance of the fever was near the end of June in two young men, Parkin and M'Kenna, who occupied a ware- houfe in South-ftreet and who died in a few days. The ware- houfe was examined, and was found to contain nothing which could be the fpecial caufe of the fever ; nor is it fuggefted that they were infeaed from abroad. No perfon received the difeafe from them. From this time till the clofe of Auguft, Weft Baltimore remained in a ftate of unufual health. In Eaft Baltimore (Fell's Point) a bilious fever had fhowed itfelf early in the feafon, and gradually fpread and grew worfe ; but was fuppofed to be no other than the common ficknefs of the feafon. It therefore excited no alarm, till the 26th Auguft, when a rumor prevailed, that the fever was fomething more than common. The chairman of the board addreffed a letter to each of the phyficians in that part of the city, requefting to be informed whether any cafe of contagious difeafe had come under his obfervation. Dr. John Coulter wrote for anfwer that fince the third week in June, a fever had prevailed and become epidemic, affeaing all defcriptions of people, but moftly thofe who labored hard, in the heat of tfee fun, intemperate perfons and thofe who expo- fed themfelves to night air after the labors of the day. The difeafe was violent, and unlefs fpeedily affailed with powerful 3*3 remedies, proved fatal. It had on that day, Auguft 26th, be- come general, and " affumed to itfelf the fole government of the difeafes," in that part of the city. " During the wet weather, in the laft of July and beginning of Auguft, it yielded, for near two weeks, to the dyfentery," which aftewards gave way to a recurrence of the yellow fever. [The reader is defired to note that faa.] Dr. Coulter calls the fever an epidemic, in contradiftinaion to imported contagion, and fays, " it is in the locality of our atmofphere, the fource of which I can perceive in every ten fteps I take in our ftreets, ponds of ftagnant water, and finks of putrid animal and vegetable matters, exhaling perpetually under a hot fun the moft offenfive effluvia." The conclufion he draws is, that the difeafe was not individually Infeaious. He then men- tions the uniformity of the fymptoms, and the correfpondence of the fever with the difeafes which have prevailed in that city and in other parts of the continent for a number of years paft. He enumerates the fymptoms, which are exaaly the fame, as obferved in New-Haven, New-York and Philadelphia. Doaors Alexander and Jaquitt agree in the faas that the difeafe was not imported nor fpecifically contagious. The board of health then called a meeting of the phyficians in Weft Baltimore, and inquired whether any contagious fick- nefs had come under their knowledge. They anfwered in the negative. Three of their number, at the requeft of the meeting, went to Eaft Baltimore and vifited a number of the fick. They reported on the 29th of Auguft, that the difeafe was not a ma- lignant, contagious or yellow fever, but the bilious remittent. Their report quieted the alarms of people. On the 2d of September the commiffioners were alarmed with the opinion of the phyficians in that part of the city, that the difeafe was fomethlng more than common. Five members of the board, with Dr. Moores, went to the point to examin for themfelves. They found the difeafe had fpread, chiefly among the poor, who lived in confined dwellings __a few perfons were dangeroufly ill; but on the whole, were convinced that the difeafe was not contagious. 3*4 The next week, the diforder affumed a more threatening afped. The launching of the frigate on the 7th of September, col- leaed many people together, who were expofed to a hot fun and fatigue, which fpread the difeafe to Weft Baltimore. The next day the board of health received regular information that there was contagion in the difeafe. A meeting of the faculty was cal- led, and fuitable direaions given to check and alleviate the ca- lamity. The whole number of interments in the city and precinds from Auguft 1 to Oaober 29th—Adults 408 ; children 137. Total 545. Number of inhabitants at Fell's Point (where the difeafe principally raged) who removed during the ficknefs 671. Thofe who remained were 2679. ^jTotal 3350. This plain and candid narrative of faas, which is certified by the prefidents of both branches of the city council and by the mayor, Mr. Calhoun, does great honor to the integrity and dil- igence of the commiffioners ; and if the laws of nature are to be relied on as uniform in their operation, this report alone will de- cide every difputed point relative to the origin and phenomena of the yellow fever. It is here decided by unequivocal evidence; evidence that precludes the carping of prejudice and the cafuiftry of intereft, that the yellow fever and the bilious remittent are the fame dif- ■ eafe, differing only in degrees of violence ; and it is agreed on all hands that the remitting and intermitting fevers are the fame I difeafe, with a fimilar difference in violence. The difeafe began at Baltimore early in the feafon, in June, and for more than two months, prevailed as a remitting fevei of the common kind, without infeaion, and it is agreed on all hands not to be of imported origin. During a wet feafon, the damp weather eaft the difeafg upon the inteftines, and it appear- ed in the form of a dyfentery—a moft important faa, which proves what Dr. Lind has afferted, that a dyfentery is a yellow or malignant fever feated in the bowels. The wet weather ceaf- ;ng, the fever refumed its former appearance, and gradually in- Creafed, till it exhibited its worfl forms and became infeaious. Had the advocates for the domeftic origin of this fever con- trived and direaed a feries of faas, to prove their own dodrines, 32S it would not have been poffible to collea ftronger evidence in their favor, than the report of the board of health in Baltimore. In Philadelphia, the difeafe in 1797 appeared, in a few cafes, as early as June—one on the 5th—one on the 9th—one on the 15th and another on the 22d. Thefe cafes, inftead of being confidered as proofs of a peftilential air, and precurfors of more general ficknefs, are thrown entirely out of the queftion, by the advocates of imported fomites. The divifion of opinions, which originated in 1793, relative to the caufes and origin of that dif- eafe, was revived with afperity. One party among phyficians contended that the diftemper was introduced into the city by the fhip Arethufa, which arrived from Jamaica and Havanna, on the 23d of July. Another party believed the fources of the difeafe to have been, noxious exhalations from putrid fubftances in the city, with an augment from the foul air of the fnow Nav- igation from Marfeilles. The evidence to fupport each of thefe opinions, is publifhed in the proceedings of the College of Phy- ficians, and of the Academy of Medicin. The city of Philadelphia was deferted by a great proportion of its inhabitants, and thus the mortality was limited to about one thoufand viaims. It prevailed principally in the fuburbs. This epidemic was followed as ufual by the influenza. By foreign publications, it appears that the catarrh was epi- demic in England in>the four firft months of 1797. I have no particulars of the violence or extent of this diforder ; but if it was fevere and general, no event is more certain than that fickly feafons will follow. What confirms this opinion, is, that in the following fummer, the plague raged in Conftantinople, on the Barbary coaft, and in Corfica. It appears by an- official letter of the French min- ifter Sotin, that there was a difference of opinion in regard to the epidemic in Corfica—fome calling it the plague ; others, a malignant fever. Thofe who called it the plague, were prepar- ed to account for it, by the tale of a Twrkifh veffel wrecked upon the ifland, with difeafed people on board. But the difeafe fubfided without very extenfive ravages. This malignant fever however occafioned no fmall alarm in England. The government fent orders to fhips cruifing in the 326 Mediterranean to have no communication with veffels from Cor- fica, and a proclamation was iffued ordering ftria quarantine to be performed by all veffels from Corfica, Minorca, Gibraltar and Spain within the Mediterranean. In 1797 the bilious plague carried off forty-five of the in- habitants of Providence. Of this difeafe, I have a minute and judicious account from Mr. Mofes Brown, which is here a- bridged. In 1791, the year when the difeafe firft appeared in the Weft-Indies and New-York, feveral perfons died of a fimilar fever in Providence. Two women died in one family, near the centre of the town, after three days illnefs. They vomitted bilious matter, and were yellow, with livid and purple fpots. The fecond, being feized two days after the death of the firft, might have taken the difeafe by infeaion ; but no fufpicion ex- ifted that the firft had accefs to any infeaing caufe. On the 14th of Auguft died another perfon in a different part of the town, and on the 21ft of September, a fourth, with fimilar fymptoms. As no alarm had then been excited by yel- low fever, little notice was taken of thefe cafes ; but the attend- ing phyfician, a refpeaable charaaer, who vifited many patients in 1797 and was affeaed with the difeafe himfelf, has fince pro- nounced the difeafe of 1791 and of 1797 to be the fame. A cafe very fimilar to thefe occurred in September 1792 ; and on the weft fide of the river, prevailed a fingular epidemic, in which perfons became yellow, with black urine, coftive bow- els, pains in the right hypochondrium, without fever. Some had petechial fpots, and one perfon, petechia, vibices and hemhor- age, yet the difeafe was not mortal, nor malignant. In 1793 a perfon from Philadelphia was ill and died of the yellow fever in Providence, but no other was infeaed. In 1794 feveral perfons had the fame difeafe, but they took it probably in Carolina, where they had been on a voyage ; the difeafe did not fpread by infeaion. On the 1 ith of July 1795, died Capt. J. Gifford, a refpea- able man, of the fame difeafe. No infeaion was fuppofed in the cafe—he was buried under arms, but no inconvenience was •xperienced from it, at the time. Yet two years after, viz. in 327 1797, his family were affeaed with the diforder, at the time when it became epidemic in the neighborhood. Several other cafes occurred, in the fame year, and one of them exhibited infedion. Thefe cafes demonftrate a peftilential principle exifting in that town, in every feafon from 1791 to 1795 inclufive; at the time when other parts ot the United States were more feverely affliaed. They were the diftant precurfors of a more general calamity in that town, which did not arrive till 1797. Sporadic cafes of peftilential fever do not render it certain but probable, that the difeafe will, in a future feafon, become epi- demic. In 1796 cholera infantum and dyfentery were prevalent. In 1797 the hydrophobia was prevalent in the ftate of Rhode- Ifland, as well as in other ftates. One T. Lyon was bitten by a dog, the wound healed, and he was feized four months after, and died. The peftilence among cats prevailed alfo in Provi- dence. In this year alfo prevailed at Weftport in the fame ftate, and on Nantucket ifland, a very malignant epidemic dyfentery. At Weftport died 30 patients of 79 who were feized. On Nan- tucket the difeafe was lefs mortal ; about too died out of 2000 patients. On examination, it, was found that under the houfe of the family firft feized, there were fome barrels of putrid fifh, and other naufeous matter. It was fuppofed alfo, that the difeafe might have been aug- mented by the effluvia of a large pond, at fome miles diftance, which had become ftagnant, filled with grafs, and the fhores ftrewed with dead fifh. A number of men, on this difcovery, opened a trench to drain off the water, and let in the tides, af- ter which, it was fuppofed, the difeafe affumed a lefs malignant afpea. The peftilential condition of the air at Providence in 1797, manifefted itfelf very early in the feafon ; the firft death occur- ring as early as May 5th—the next on the 25th of June—the third on the 4th of July—the fourth on the 27th—the fifth on the 29th, and the fixth on the firft of Auguft. The fymptoms in all tfiefe cafes, were the predominant ones of the true yellow 328 fever ; and the bodies exhibited more or lefs petechia; and vi- bices. Thefe cafes occurred before the arrival of the fchooner, to which popular clamor afterwards imputed the whole evil. Thefe were the fcattered precurfors, which, had the fubjed of peftilence ever been inveftigated, with philofophical ingenuity and Chriftian candor, would have rendered the epidemic a prob- able event to the citizens of Providence, as early as July and would have taught them to ufe all human means to avoid or miti- gate the calamity. On the 8th of Auguft arrived the fchooner Betfey, Capt. Barton, from the Mole of Cape Nicholas, after 24 days paf- fage. Her cargo was only a few hogfheads of coffee. She lay at the wharf, till the 20th, when an increafing alarm from new cafes of the fever induced the police to order her to be removed and cleanfed. On enquiry, it was found that three of the fchooner's people had been ill in the Weft-Indies, but no one died. One of thefe only had been ill on the paffage, but had recovered fb as to do duty, feven days-before her arrival. There were five per- fons on board, during the paffage, none of whom were affeaed by difeafe from infeaion or other caufe. The death of Mr. Arnold, the cuftom-houfe officer, who was faid to have vifited the fchooner, and feveral of his family, gave rife to the report that the fever began from fomes on board of her. This point will be hereafter difproved. Certain it is, that another officer of the cuftoms flept on board of the fchoon- ex feven nights ; another five, and another young man two nights, with Brown, the owner of the blankets hereafter to be mention- ed ; all of whom efcaped difeafe of any kind. It was alfo faid that the woman who wafhed two blankets, belonging to a difeafed feaman, took the fever and died. On inveftigation, this proved to be an idle tale. The blankets were owned by one Brown, who had not been fick ; and not having any ufe for them in warm weather, they had lain in his cheft. On his arrival, they were carried home, fpread out on the fence to air ; they were then carried to his filter's to be wafhed and lay two days before the work was undertaken. The day 329 after the wafhing, the women were taken ill; which was two early for the operation of infeaion, unlefs highly concentrated. But in fad the blankets were not infeaed ; never having been ufed by any difeafed perfon ; and the mother and others who handled them, when firft opened, never had the difeafe. But ftronger circumftances attended this cafe. The blanket belonging to Rophy, the only fick man, on the paffage, and his other clothes, worn during his fever, and colored yellow, by his perfpiration, were carried to his houfe ; the blanket fpread out for children to play on, before it was wafhed ; afterwards waflied by his wife ; and no perfon took any difeafe from his clothes or blanket. Such are tales of imported difeafes, raifed by ignorance and propagated by intereft, pride or credulity, to which the bufinefs of the merchants and the commerce of the country are to be facrificed ! Many other reports were fpread about the infeaion from this fchooner which, upon ftria enquiry, were found to be equally groundlefs. Such as the introduaion of the fever into Warren, where the veffel flopped, on her way to Providence. The cafe was, one Cole, an officer of the cuftoms, fculled a large boat, a mile or two, againft the tide, in a foggy evening ; went on board, wet and fatigued ; without refrefhment or change of clothes, flept in a cabin with broken windows, took a fevere cold ; repeated his vifit to the fchooner the next day ; on the third day went to Providence, a diftance of ten miles in the rain ; tarried two nights without a change of clothes; returned on foot, and was taken ill of a bilious fever and died in about feven days. Yet after all this fatigue and imprudence in the man, enough in all confluence to kill him, men are found weak enough to charge his difeafe to the fchooner. But it happens, that other fimilar cafes of fever occurred in Warren, in perfons who had never vifited Cole or the fchooner ; i^nd one at the diftance of three miles from the town~ The whole tale therefore comes to nothing. One fad more, and I will quit the fubjea of correaing the popular errors on this head. The men belonging to the fchooner S s 33° were difmiffed at Providence and returned to their families, with their fea clothes of courfe. My informant took pains to enquire of every family, whether any of them had been infeaed; and he found not one inftance, altho the families confifted of about forty fouls !—The cafe of the unfortunate family of Mr. Arnold would afford fome flight ground to fufpea the infeaion to be communicated from the fchooner to him or his fon, the latter having vifited her ;* but it happens that Mr. Arnold's wife, who had not been on board, nor otherwife expofed, was feized fifty- fix hours before her fon and more than three days before her huf- band. Thus the reports of infeaion from abroad, when well fifted, vanifli into fmoke ; and I am perfuaded this would gene- rally be the refult, if men would be faithful to themfelves, to truth and their country. On the 12th of Auguft, the fever took a more rapid fpread, probably from a fudden alarm by the burning of two tons of hemp, by means of a fpark from a blackfinith's fhop, as it was pafling the door. This was four days after the arrival of the fchooner, and occafioned the popular clamor which was raifed about her infeaion. But the appearance of the difeafe long before her arrival is decifive of the queftion. This difeafe had its own atmofphere ; raging moftly in a part of Providence much expofed to the effluvia of great colkaions of filth in vaults, from a diftillery, and in other places. Some cafes however occurred in other fituations; and many parts of the ftate exhibited the peftilential principle, in fporadic cafes, or local epidemics, as at Briftol, Warren, Greenwich, Indian Point, Gloucefter, Warwick, &c. In Providence, the difeafe affeaed fifty-fix families—8 before the arrival of the fchooner, and 48 afterwards. In 33 of thefe families, only one perfon in each, had the fever; and as fome of the families are large, the infeaing principle could not have been very powerful. In the large houfe, where lived the women who were firft taken ill, after the fchooner arrived, refided 9 * It is not rendered certain that the father had been on board; but that the fon had, is not quefliontd ; fo had at leaft one hundred others, who were not afterward affected with the difeafe. 331 ramifies, confifting of 37 perfons, only 12 of which were af- feaed. In the hofpital the nurfes and attendants all efcaped. Some inftances of this difeafe appeared in the following win- ter ; and there were cafes alfo of the ulcerous fore throat. In the north part of the town, fome cafes of the yellow fever oc- curred in the laft fummer—1798. In 1797 a malignant fever is faid to have been introduced in- to a village in Chatham, on Conneaicut river, by a veffel from the Weft-Indies. I underftand that it was confined to a clufter of houfes by the water ; but I have not been able to colka the faas in detail, altho I have written letters for the purpofe. During the late peftilential period, the ftate of the atmofphere produced its ufual effeas in winter ; which appeared in the ex- traordinary fymptoms of pleurify and peripneumony. It has already been remarked that in periods when plague and other mortal epidemics rage in fummer, the difeafes of winter affume new fymptoms. The pleurify, at fuch times, has often become epidemic and even infeaious. It is in faa a modification of the fame peftilential principle, as that which renders bilious fevers in fummer epidemic and infeaious. The fatal effeas of this fpecies of pleurify in Conneaicut, in the winter of 1761, have been mentioned. In the winter of 1795-6, after the epidemic in New-York, feveral cafes of a fimilar kind occurred, and an able phyfician of plethoric habit and ftrong fibres, fell a vidim to a peripneumony, with anomalous fymptoms. In the following winter, a fimilar diforder attacked many people in Connedicut. Three men in Hartford, of one family, two brothers and a coufin, all men of robuft health, were at- tacked and carried off in the compafs of a few days. Others of the fame family, and feveral perfons of a fimilar habit were affeded, but recovered. It was far lefs general than in 1761. This fpecies of pleurify appeared in Philadelphia as early as September 1791, the month when the malignant fever prevailed in New-York. A patient of Dr. Rufh had a " red face, infla- med eyes, a perpetual tolling and fighing, ftrong animal powers, but weak pulfe and fizy blood." In February 1792 many cafes of fimilar pleuritic fevers occurred in Philadelphia—difeafes af- 33- famed the inflammatory diathefis which has remailully cha'rae-* terized the epidemic of the laft peftilential period. In the fpring of the year 1798, a mortal fever raged in Fred- ericktown, Maryland, beginning with laffitude, chills and pain in the head, and producing, on the third day, vertigo and fpafm in the breaft. Letter from Dr. Baltzell to Dr. Rufh, dated May 2, 1798. In fummer and autumn of 1797, a malignant fever, attended with dyfentery, was epidemic in Portland and its vicinity, in the diftrid of Maine. The dyfentery fubfided in Odober, but the fever continued. It appeared in the country, as well as town ; and was ufually conquered by the ufe of alkaline reme- dies. Many of the patients had a yellow fkin and the predomi- nant fymptoms of the yellow fever of our cities. In one inftance, this difeafe put on the form of peftilence. A merchant, in a country village, where no fufpicion of infedion could be enter* tained, was feized, with a malignant fever ; he lingered till the 36th day, and died highly putrid. His nurfe was feized and died ; after death appeared livid fpots on the body. A fervant alfo took the difeafe and died. The nurfe communicated the difeafe to three perfons in the family where fhe lay ill. This laft inftance is dscifive evidence that the peftilential yel- low fever not only originates in our country, but in villages, in the 44th degree of latitude, a more temperate climate than that of New-York and Philadelphia. In the winter fucceeding, the peftilential principle ftill exhib- ited its effeds. The fever continued to prevail, being ufhered in with naufea, vomiting and chills fucceeded by heat; but it was generally accompanied with a fore throat and fcarlet efflo- refcence. It prevailed in almoft every town in the county. Dr. Barker's letter, Med. Rcpof. vol. 2. 147. The year 1798 was remarkable for the moft general preva- lence of the plague of our climate, that has been known ; and in fome cities, the difeafe was peculiarly malignant. The preceding winter had been unufually long and cold—the May following was dry beyond what is recolleded in any former years—June was remarkable for deluging rains, which occafioned floods in the Connecticut, Delaware and Sufquehannah rivers. 333 Which did no inconfiderable injury. Two or three of the firft days of July were exceffively hot, and fucceeded by twenty day9 of very cool weather—then commenced a long period of the moft fultry weather ever known in our climate, accompanied, in fome places, with great rains. Catarrhous fevers were frequent in the fpring, the conftant forerunners of autumnal ficknefs. Bilious fevers alfo occurred, in a few cafes very early, indicating the predominant condition of the atmofphere. In fummer and autumn, the grafs-hoppers multiplied to fuch a degree from Pennfylvania to New-England, as to devour vegetables, and effentially injure the paftures and grafs fields. The peftilential fever in Philadelphia appeared early in the feafon—a number of cafes in June, and ftill more in July. In Auguft early, the city was alarmed and foon deferted by at leaft three fourths of its inhabitants. The difeafe was unufually mor- tal ; and extended to the remoteft parts of the city, where it had not formerly prevailed. Owing to this circumftance, fome families fuffered, which had efcaped in former years. The num- ber of deaths amounted to about 3440. The difeafe, as ufual, abated with the appearance of froft; but individuals were at- tacked with it, and carried off, in the midft of the following winter. It is alledged by fome perfons that the fever was introduced Into Philadelphia by the fhip Deborah, which arrived from Jer- emie, and anchored near Race-ftreet wharf, on the 18th of July. It is admitted that perfons who went on board, foon af- ter fickened and died ; and fo did others ficken and die, without going near that fhip. The truth is, many cafes of the difeafe had occurred three or four weeks, before her arrival. The fhip had loft people by fever on her paffage and might be infeded; and perfons vifiting her might receive that infedion ; but thefe fads do not reach the point. The epidemic began in all parts of the city, in fcattering cafes, previous to the arrival of this fo- mes, and had the fhip never arrived, that epidemic would have ravaged the city. This is evident from the number of its pre- curfors. This peftilential fever carried off fifty-feven perfons in the 334 village of Marcus Hook, where the firft petfons feized were a fhallop-man and others from Philadelphia. But many cafes oc- curred which could be traced to no infedion. See Dr. Sayre's letter ia Currie's Memoirs, p. 136. In Chefter died 50 of the fame fever. At Wilmington, in the ftate of Delaware, thirty miles from Philadelphia, the fame difeafe raged with more than its ordinary mortality. Its vidims amounted to 250. It appears that the difeafe was introduced by the fugitives from Philadelphia, and by watermen who ply between Wilmington and Philadelphia. See Dr. Tilton's letter in Dr. Currie's Memoirs, p. 138. The fever alfo prevailed in New-Caftle and at Duck creek in the fame ftate. Letters from refpedable phyficians, in the public prints, have informed us that this difeafe prevailed alfo in fome paits of New- Jerfey, as at Bridgetown and Woodbury ; and efpecially near the meadows on the borders of the Delaware. From careful examination, it was found that the difeafe muft have originated where it exifted ; no into courfe having been held with infeded places. In fome inftances the fever was probably infedious. At Norwalk in Councdicut feveral perfons died of the fame diftemper. The phyficians are doubtful as to its origin ; as fome cafes may be traced to a difeafed perfon who had been in New- York. Three cafes however occurred at fome miles diftance from the heart of the town, in perfons who had not been in the leaft expofed to infedion. M. S. letter from Dr. Betts. In the firft week of Auguft, appeared a bilious fever in New- York, between Old flip and Coemies flip, in the ftreet next to the water ; a place remarked for great accumulations of filthy fubftances. By the exertions of the Health Commiffioners, in covering thefe nuifances with frefh earth, this alarming fever fubfided in that neighborhood, and difappeared by the 26th of that month. But on the 12th, the peftilential fever appeared in other parts of the city, and about the 20th, began to extend and affume a more formidable afped. The diftrid of the city, fubjeded to its moft deadly effeds, was that fedion comprehended between 335 John-ftreet and Beekman-ftreet, particularly in Cliff-ftreet and its. neighborhood. The probable caufe of this effed, was the fetid air from large quantities of fpoiled beef, ftored in the cel- lars in Pearl-ftreet, on the windward fide of this fedion. The cellars were filled with water by heavy rains, or were other- wife damp; which circumftance, added to the extreme heat of the feafon, occafioned a greater lofs of falted provifions, than perhaps was ever before known. To augment the effed, large quantities, of pickle had been difcharged, in the procefs of re- packing beef not yet fpoiled, but in a bad ftate, which pickle had been carried by the gutters into a fewer in Burling flip, from which iffued a very offenfive fmell.* About the laft of Auguft, the inhabitants of New-York were greatly alarmed; fome removed from the eaft to the weft fide of Broadway, a part of the city which has hitherto been exempted from the violent effeds of the yellow fever ; but a great pro- portion of the people deferted the city. The difeafe was more malignant, than in its preceding vifits, and exhibited more fre- quently the bubo and carbuncle. It extended over two thirds of the city, and numbered with the dead about two thoufand of its inhabitants. I am informed the difeafe was lefs generally charaderized with the inflammatory diathefis, and that venefec- tion was lefs generally attended with falutary effeds, than in for- mer years. This difeafe exhibited little infedion, beyond the limits of its own amofphere. In the hofpital, at a little diftance from the * There is reafon to believe, that fait, if not fufficient to prefervc the article to which it is applied, renders it doubly noxious in a ftate of putrefaction ; and that a fmall quantity of fait will accelerate the pro- cefs of putrefaction. From an experiment related to me by Mr. Mofes Brown of Providence, it is proved that a piece of flefh, in pure water, will not putrefy as foon as in water, in which a few grains of fait have been diflblved. Do not the faline particles of the air, on the fea coaft, render the putrefaction of flefli and vegetables more rapid, and the exhalations more deleterious, than perfectly frefh water ? And is not this one caufe, why peftilential difeafes appear firft, and are moft general, in mari- time places ? Dr. Coglwell informs me that a boat-man on Connecticut river, in the hot weather of 1798, contracted a violent fever of which he died, by.fleeping in an open boat, near a quantity of pickle which had leaked out of a barrel of falted provifions. The difeafe was of a very ma- lignant kind. 33$ city, were admitted about 300 patients, ill with that difeafe , yet fixteen nurfes, feven wafherwomen, and the boatmen whq conveyed the fick from the city to the hofpital, all efcaped. Dr, Douglafs, the attending phyfician, efcaped the difeafe, until Odober, when he vifited his friends and flept in the city, three days after which he was feized with the fever. Sec Letters from the Health-Office, by Dr. Bailey, whofe real, talents and induftry, in his employment, have rarely been equalled. The laft fad is very important towards correding the popular errors refpeding the contagion of this fever. In the city per- fons took the fever—in the hofpital they did not. That is, the diftemper has an atmofphere, in which it is readily contraded—■ beyond that atmofphere, it is not infedious. In other words, it is a condition of the atmofphere, and not the effluvia from the fick, which is to be dreaded. Thus, in 1797, the fugitives and fick from Philadelphia did not fpread the fever in Wilmington—in 1798, they did. That is, in 1797 the atmofphere of Wilmington would not generate and nurfe the difeafe—in 1798, it would. In Bofton, the difeafe began near the town dock and the neighboring wharves, in the month of June ; but its moft vio- lent effeds were experienced on the fouth fide of Fort-Hill, an elevated part of the town and expofed to free air. This cir- cumftance has occafioned no fmall furprife ; but as the fever of 1796 began in that part of the town, perhaps we may find the caufe in the very extenfive flat, between Bofton and Dorchefter point, which is uncovered at low water ; perhaps in the expo- fure of that hill to the dired rays of the fun ; perhaps in the na- ture of the foil which is clay of a folid texture, and fitted to re- tain on its furface whatever impure fubftances are thrown from houfes. The fever afterwards invaded the north part of the town, and a ftreet near the pond ; fuppofed to be excited by noxious exha- lations. Some parts of the town, which are low and filthy, ef- caped the fever. At firft it attacked the moft robuft young men, and thediath- efis was highly inflammatory. Later in the feafon, it attacked 337 perfons of all ages and habits. At firft it was not infediouij but in the later ftages of its progrefs, it exhibited infedion. It difappeared with the arrival of froft, after carrying off nearly 200 patients. M. S. letter from Dr. Eliot. See a full account of the difeafe in a letter from Dr. Rand, publifhed by order of the Academy of Arts and Sciences. This gentleman obferves that no infedion appeared, except in places where the difeafe was originally contraded.* MalTachufetts Mercury, Feb, 8, 1799. The fame malady appeared in Portfmouth, New-Hampfhire, with equal mortality, as far as it extended; but its progrefs was limited to one ftreet near the water. New-London, in Connedicut, is fituated in a very healthy part of the country, on a harbor, whofe fhores as well as the furrounding lands, are dry and rocky—its population about 300Q inhabitants. In the laft week in Auguft 1798, this town was fuddenly in- vaded by the plague of our country, which began in the family of Mr. Bingham, keeper of the Union coffee-houfe. No vef- fels from the Weft-Indies, no fick from other places, occur, in this inftance, to help out popular credulity. The idea of in> portation is abandoned by the citizens of the town. The fever was very fatal within its atmofphere, which was confined to Bank ftreet and its vicinity ; a part of the city well built, clean and airy as any ftreet in the town. Within a fmall fpace, were fifteen houfes, inhabited by ninety-two perfons—of which ninety were affeded with the difeafe; thirty-three of this number died, and two only efcaped the fever. The difeafe prevailed about eight weeks and deftroyed eighty-one lives. Printed account of the fever by Charles Holt. On enquiry I find that this difeafe in New-London had its precurfors, in fporadic cafes of the fame fever, in the three pre- ceding fummers. In 1795, died Dr. Jofeph W. Lee with all the fymptoms of the yellow fever. Some inftances occurred in * That is, infection was attached to the place, rather than to the pjrfem of the difeafed—a fact which is true of every peftilence. T t 33$ 179°" 5 and in 1797 died of the fame, Matthew Giifwold, Efq. and foon after his mother; indicating the communication of in- fedion. Yet in thefe years, it did not fpread and become epi- demic. The peftilential period however was progrefling in that town, as appears by the bills of mortality; for the ordinary number of deaths does not exceed 60 in a healthy year ; but in 1795, the number amounted to 86—in 1796, to 80—-in 1797, to 101—in 1798, to 133. Here we obferve a great augmenta- tion in the mortality of the town, feveral years before the crifis of peftilence, and efpecially in the year next preceding it. The importance of this fad towards a right underftanding of the caufes of epidemic peftilence, cannot be miftaken. Confiderable quantities of falted fifh, which lay in certain flares in New-London, and which had not been well cured with the afual quantity of fait, became fetid and offenfive, altho not pu- trid, and affumed a red eaft with a flimy feeling—it alfo loft its texture and firmnefs. This was opened and fpread in the ftreets for the purpofe of being dried ; and from its offenfivenefs and vicinity to the place where the difeafe firft appeared, it is fuppo- fed to have been an exciting caufe of the fever. This opinion has doubtlefs fome foundation ; but putrid fifh will not always occafion difeafe. It is probably true that the bad ftate of the fifh Avas partly owing to a previous bad ftate of the air; altho it afterwards became a caufe of a worfe flate of the air. What feems to put this beyond doubt, is, the unufual number of mufketoes, in the adjacent country, and the multitudes of flies of uncommon fize, exceeding what had been before obfer- ved. With thefe phenomena before our eyes, we can be at no lofs to account for the peftilential fever of New-London. The ufual lake and river fever prevailed in the fame feafon, in many of the interior parts of the country ; as at Royalton in Vermont, on the Grand Ifles in Lake Champlain, at New-Mil- ford in Connedicut, and in various parts of the ftate of New- York ; in which places, it was attended with confiderable mor- tality. Sporadic cafes occurred in all parts, and in the healthieft fituations, of the country. In many places, intermittents and dyfentery were unufually violent and obftinate, 339 I have no account of the temperature of the weather in any part of Europe, during the fummer of 1798 ; except that in fome parts of Sweden, the firft months of the fummer were ex- ceffively dry, as the month of May was in America, A peftilential fever appeared in Italy in June; but I have no details of it3 progrefs. It is however to be obferved that this fever was preceded by a violent earthquake in fome part of the Tufcan territories, in the month of May, which did no fmall injury. In autumn broke out a peftilential fever on the Baltic, in Dant-' zick or its vicinity. The government of Denmark, in confe- quence of official information of the prevalence of this difeafe, direded all fhips from Dantzick and the neighboring ports to be watched with vigilance, and appointed a committee of quarantine. According to the report of a mafter of a veffel, there was an eruption in Teneriffe in the fummer of 1798, which lafted fev- eral weeks. This volcano had been quiet for 94 years. In November and December, the peftilence in America was fucceeded as ufual by influenza, which was very prevalent in all parts of the country, and in the fouthern ftates attended with fome mortality. This was merely a change of the form of the epidemic. The winter of 1798-9 was very long and fevere in both hem- ifpheres. In the United States, it began about the middle of November, with fnow, and a heavy fall of fnow on the 18th and 19th was followed by fevere cold that lafted till the fecond week in January. From this time, there was a relaxation of cold for about three weeks, and the ice in Connedicut river gave way. But in February oommenced fevere cold, which contin- ued', for the moft part to the vernal equinox. April was alfo cold; fevere frofts occurred often, and checked vegetation. On the 2d and 8th of May were confiderable faUs of fnow, followed by froft. On the morning of the 4th and 5th, we had ice at New-Haven as thick as window-glafs. Peaches bloffomed about the middle of May, and apples were not in full bloom, till the 22d. This long duration of cold exhaufted all the barns of hay and other fodder, and multitudes of cattle perifhed in various parts of the country. 54<* In Europe, the winter was equally fevere. The rivers iri England, Germany, Holland and France were covered with folid ice, and at the breaking up of winter, the Rhine rofe and burft its barriers, inundating many parts of Holland with terri- ble deftrudion. The feverity of the winter was felt even in the fouth of Italy, and the French and Neapolitan troops fuffered greatly from fnow on the Appenine, in the vicinity of Naples. In Siberia, we are informed by the public prints, perifhed whole villages of men and cattle by the feverity of the froft. In America, the difeafes of the winter were charaderized by the predominant diathefis of the reigning epidemic conftitution, a yellow fkin and bilious difcharges. An earthquake of confid- erable extent was felt in the Carolinas on the 12th of April- What will be the ftate of health in the enfuing fummer, muft be left to be determined by the event. The prefent peftilence has been long and fevere and the citizens look with impatience, for the ufual falubrious ftate of their atmofphere. In Auguft, about the time the peftilence began to fhow itfelf in New-York, immenfe numbers of flies died fuddenly, and oc- cafioned no fmall fpeculation and alarm. Some were found on the floors ; others adhering to the ceilings of rooms, and what is fingular, their bodies became white. A peftilential air ufually generates flies in unufual numbers; but on this occafion, fome fudden change in the elements, deftroyed their lives. How Kttle do we know of the powers of the elements, and the nature of the alterations in them which produce fuch aftonifhing effeds. Will imported infedion account for fuch phenomena ? This is the beft ftatement of facts I have been able to make from fixteen months inveftigation. It is not improbable that fome miftakes have occurred, which more time and more ample materials, would enable me to corred. But I truft that the fubftance of the ftatements is accurate, and that no error of con- fequence will be found to refult from them, to impeach the gen- eral principles fuggefted in this work. 34* POSTSCRIPT. Additional fa fis, colkaed on a journey which I made through the Northern States, while this volume was in the prefs, JLNthe autumn of 1732 raged in New-York a malignant, in- fedious fever, of which died feventy perfons in a few weeks. M. S. of Mr. Alexander. In 1745 a malignant bilious fever prevailed in New-York, of which died an eminent phyfician of the city, Dr. Nicoll. By the defcription of the difeafe, given to me by a gentleman who Was affeded with it, there appears to be no queftion that it Was the Tame difeafe now called yellow fever. About this time, for the year is not exadly known, a malig- nant epidemic difeafe laid wafte the Indian tribes. By the de- fcription of the fymptoms, as given by Indian traders, then among the tribes, and ftill living, it is certain this was the infec- tious yellow fever. In confequence of this diftemper, the Sene- cas removed their quarters two or three times, in a few years—it being a pradice among the natives to abandon the plSce infeded with this plague. The difeafe was confined to the Indians—the white people, living and trading with them, not being affeded. In 1746 the Mohegau tribe of Indians, between New-Lon- don and Norwich, was wafted by the fame malady. Dr. Tracy of Norwich now deceafed, was the only white man affeded—he attended them as their phyfician. From Mr. Philemon Tracy, a Ton of the dodor, who has taken the trouble to examin a Mo- hcgan prieft, a man of good fenfe and integrity, who was him- felf affeded by the diforder, I have the following account of this peftilence.—That it appeared in Auguft and prevailed till cold weather—that about one hundred of the tribe perifhed—. that it was the year after the redudion of Cape Breton (of Courfe 34* In 1746—and Dr. Tracy's books confirm the dates mentioned by the Indian)—that the patient firft complained of a fevere pain in the head and back, which was followed by fever—in three or four days, the fkin turned as yellow as gold, a vomiting of black matter took place and generally a bleeding at the nofe and mouth, which continued, till the patient died. Thefe are the words of the old Indian, as penned at the time by my in- formant. It will be remarked that this was a local peftilence, the fever being confined to a fingle tribe of Indians and not prevailing in the neighboriBg towns. But it will be remarked alfo that this Was the fame year, it prevailed in Albany, when the bills of mortality were generally high. I have afcertained that the canker-worm, which lately ravaged the fruit trees in New-England, appeared as early as 1788 or 1789. A fatal malignant difeafe raged among the tribes of the Mo- hawk Indians, about the year 1776, and reduced fome of them to a few men. From Dr. Wheeler of Redhook, on the Hudfon, I learn that the angina fcarlatina appeared there in January 1789 and prevailed till April—it prevailed alfo in the two fucceeding win- ters. The influenza, in that year, firft appeared there about the middle of Odober, and prevailed two months, among all ages and both fexes. Catarrhal coughs have been prevalent every year, fince that time. In thelpring of 1793, angina fcarlatina, mumps and catarrhal coughs prevaiW.till June, and difappeared. Soon after commenced the remitting fever. In fome cafes the paroxyfms invaded the patient in the form of madnefs. The reader will note that in our interior country, the remit- ting fever of that diftinguiftied year, 1793, had nearly the fame fpring precurfors, as the yellow fever in Philadelphia. The meafles at Redhook in 1795, partook of the charader of the preceding epidemic fevers ; beginning with a highly in- flammatory diathefis, and fometimes ending in typhus, with pe- techia, vibices and hemorrhagy. Pleurifies had the fame char- ader. 343 At Brattlcborough, on the Connedicut, a family by the name of Morgan were feized in 1791 with a fever of the typhus kind, and "fix of them died. Several perfons who vifited the family took the difeafe and died, and there its progrefs ended. The family refides in a healthy fituation, near a fmall adive ftream of water ; and no vifible caufe could be afligned for the origin of this diftemper. Thefe fads are taken from Dr. Hall of that town. It will be remembered that this was the year when au- tumnal difeafes firft put on the malignant afped of our late pefti- lence, when the plague broke out in Egypt and the yellow fever in the Weft-Indies began to affume what Dr. Chifholm calls unufual fymptoms. Dr. Center of Newport informs me that in 1798 occurred in that place many cafes of a bilious fever bearing fome refemblance to the infedious fever ; and one cafe of decided carbuncular and glandular plague, in a man of robuft conftitution. There is no pretence of foreign origin, in any of thofe cafes. From fundry gentlemen living in Chelfea, a village at the landing in Norwich, I learn that two or three cafes of malig- nant bilious fever occurred there in 1798, marked with the ufual fymptoms of the infedious fever. Some of thefe cafes could not poffibly have been derived from infedion. One of the pa- tients might have contraded his difeafe at New-London. Dr. Holyoke of Salem, in Maffachufetts, informs me that in 1798, many cafes of malignant bilious fever occurred in that town, which could not have been derived from infection. From Dr. Woodruff and Dr. M'CteHan of Albany, I learn that feveral cafes of malignant bilious fever appeared in that city, in 1798, marked with all the fymptoms of the peftilence of our cities and which muft have originated in that place. About one half who were feized, died. The firft cafe of influenza at Albany in 1789 is noted by Dr. MClellan to have occurred on the 30th of September. This was precifely the time of its appearance at Philadelphia, and a little after its firft appearance at New-York. In the coun- try, between New-York and Albany, it did not appear till a week or two later. Thefe fads prove that this difeafe falls on diftant places at the fame time, 344 The fcarlatina anginofa appeared at Albany in the winter and fpring of 1793, about the time it did in New-York and Phila- delphia. In every part of our country, one remark has been made by phyficians, that from the year 1792 or 3, intermittents and re* mittents have become more numerous and obftinate, and attend- ed with unufual fymptoms. In many places, thefe difeafes have been multiplied in a ten-fold ratio ; elucidating the principles of the great Sydenham, relative to " Conftitutions of Air," and demonftrating the exiftence of a general caufe in the infenfible properties of the atmofphere, to which we may and muft afcribe the peftilence of our maritime towns. In 1798 multitudes of dead pike were obferved to float down the Mohawk and Hudfon. From Dr. Thatcher I learn that for fome years paft, an au- tumnal fever has prevailed in Plymouth, in Maffachufetts, of the remitting kind, with low typhus fymptoms. In winter it take? the type of the nervous fever. It was very prevalent in 1798 in that and a neighboring town. From Dr. Smith of Hanover, in New-Hampfhire, and Drs. Green and Trafk of Windfor, in Vermont, I have obtained information refpeding a very infedious fever which prevailed in thofe towns and the vicinity in 1798. This difeafe is defcribed by Dr. Spalding in the Medical Repofitory, -vol. 3. p. 5. It approaches nearly to the typhus mitior of Cullen, but the fiery red eye at the invafion feems to indicate its alliance to the in-? fedious fever of our ckics ; and it refembles the difeafe known by the popular name of long fever. This fever, in Windfor and Hanover, was preceded by dyk entery of uncommon malignancy in 1797, which, in Windfor, was attended with an unufual inflammation of the lungs. Tlia difeafe which preceded thefe epidemics was the fcarlatiRa angino- fa, which was very prevalent in 1796. It is worthy of notice that in all parts of our country, the au- tumnal infedious fevers have had precurfors in other epidemics, efpecially catarrhal complaints and anginas. I do not find an ex-, caption to this remark, 345 This fever at Windfor deferves further to be noticed for its in- fedious or contagious quality. It was fir lefs fatal, but mere in- fedious than the yellow fever of our cities. Nurfes often took the difeafe, and when they returned to their dwellings in diftant towns, rarely failed to communicate it to the whole family. This is a phenomenon rarely, perhaps never exhibited by the peftilence of our maritime towns, which has an atmofphere of its own out of which it is not communicated. I have examined perfonally the pofitions of many of the towns where this fc-ver and dyfentery have been moft prevalent, and I find no where any marfh that can rationally be fuppofed to originate thefe diftempers. In general the towns are fituated on a bafis of clay, between high ridges of land or mountains, where the heat of the fun is greatly concentrated, and on the margin of rivers. To this defcription, there are fome exceptions as to the foil; fome towns being on fand or gravel. The neigh- borhood of frefh ftreams of water cannot be admitted as a caufe, of thefe fevers—nothing being more falubrious than fuch ftreams. But I am perfuaded from careful obfervation, that, under a pef- tilential conftitution of air, great heat is the immediate exciting caufe of autumnal fevers, in fituations not expofed to marfh effluvia. With refped to the origin of the peftilential fever in Portf- mouth, in 1798, the fads are as follow. A laboring man, who was given to liquor, received his wages on Saturday evening. He was feized with the malignant fever, ^nd died on the next Wednefday. While he lay ill, a veffel ;.rrived which had loft a man or two by the fever on her voyage, but no perfon was ill on board, at the time of her arrival. Some cf the perfons who afterwards died of the fever, had been on board of that veffel ; but whether they took the difeafe from in- fedion or not, cannot be known. The firft cafe occurred before the arrival. This is an agreed point. I have thefe fads from two of the principal gentlemen of that town, one of them a refpeda- ble phyfician; the other, the perfon who paid the wages to the man who firft died. All my enquiries have been made at the fources of corred information ; and I find every where popular reports are falfe or incorred. Yet popular reports are received as truth by many phyficians and writers, and are made the bafis of falfe and pernicious theories, both in America and Europe^ U u 34& The fever in Portfmcuth was limited in its progrefs to the northern part of the town. In the fouthern part, at the fame / time, prevailed a malignant dyfentery, which was as mortal as the >/ fever in the northern part. The line of divifion was drawn by a wide ftreet or fquare on which ftands the court-houfe. The fcar- let fever had been prevalent in the town for two years preceding. In 1799, the prefent fummer, many perfons have taken the peftilential fever from veffels arrived from the Weft-Indies ; but in moft, or all cafes, the fever has become extind, without any confiderable mortality. In Bofton, the mortality was limited to two or tkree perfons. The cafe at Newburyport was fingular. A veffel went and returned from the Weft-Indies, without a cafe of malignant fever ; but as fhe arrived at the mouth of the river Merrimack, 18 days from St. Thomas's, a boy was feized with the fever, and afterwards one or two others. Several perfons took the difeafe and died ; but people left the vicinity, and the diforder be- came extind. This was a fever generated on board of the veffel. The beginning of the fummer of 1799, tho late, was favor- able to vegetation, and the firft crops were good. Wheat, which had been blafted, for feveral preceding years, in the eaft- ern ftates, was excellent. But in July commenced a moft diftreffing drouth, in all the northern ftates ; and particularly in the middle ftates, and the interior country; by which the maize, buck-wheat and potatoes Were greatly injured. In fome parts of the ftate of New-York, the maize was totally deftroyed. Over the eaftern ftates, a fpecies of caterpillar of fmall fize appeared in unparalleled numbers, covering the wild cherry-tree, the apple, the willow, the afh, and the hickory. In fome parts, a large caterpillar, with variegated colors, ftripped the black oak of all its leaves. Grafs-hoppers were as numerous as the blades of grafs, and in fome places, injured greatly the grafs and other vegetables. But efpecially to be noted were the fmall toads of the color defcribed by Fernelius, " Coloris cineritii" like afhes ; of the fize of a filbert, and in numbers not to be eftimated. Thefe were numerous alfo in 1798. They anfwer the defcrip- tion of thofe which medical writers of former ages obferved to be the forerunners and companions of peftilence. At what time 347 they appeared and difappeared, is not exadly known—they were moft generally obferved in July. In the fpring prevailed influenza or catarrhal fevers; in fome places cynanche maligna ; and generally rheumatic complaints, and flight ulcerations of the throat. In many places, the fevers of winter were charaderized with a yellow fkin and bilious dif- charges. All thefe marked the continuance of a peftilential atmofphei e. The plague fhowed itfelf early, in fcattered cafes, in Phila- delphia ; but difappeared, to the unfpeakable joy of the inhabit- ants. Alas ! When fuch cafes appear in July, and efpecially if other difeafes in winter and fpring manifeft fymptoms of the pre- vailing epidemic, it is hardly poffible that our cities fhould efcape a peftilential fever in autumn. This terrible fcourge renewed its ravages in Philadelphia and New-York ; and in various parts of our country, bilious fevers appeared with malignant fymptoms. At Hartford, on the Connedicut, appeared the malignant fever in Auguft, to the furprife of the inhabitants and of the ftate. People who have no juft ideas of the nature and origin of this difeafe, attempted to find the caufe in fome veffel from the Weft-Indies ; but being difappointed^ reforted to a fmall coafting veffel. On examination it appears, that this veffel was ufed as a market boat between Connedicut river and New-York i—the mafter had died in June, but of what difeafe, I am not able to learn. Another mafter took poffeflion of her, and find- ing her very dirty, with the remains of various vegetables, he overhauled her and gave her a thorough cleanfing. He took in at New-York a cargo of fait, and failed to New-Haven, where the veffel Jay fome time, about the middle of July. Here the fait was purchafed by a merchant of Hartford, and the veffel ordered round to that place, where flie arrived and difcharged her cargo, in the beginning of Auguft. From the time the vef- fel left New-York, to the time of difcharging the fait, muft have been from four to fix weeks. After leaving Hartford, and go- ing down the river, the mafter and mate of this veffel were fei- zed with the fever and died. Inftead therefore of being im- ported, the fever was exported. Some attempts were made to trace all the firft cafes of the fever to that veffel; but it does not appear that more than one 348 pt.fon who had the difeafe, was ever on board ; and it is proved that moft of the perfons affeded were never near that veffel and never vifited the fick. It is proved further that of ten or twelve perfons employed in unloading the veffel, not one was ever af- feded by the malady. Yet even in this cafe, the filly talc of importation is fwallowed with eagernefs by the advocates of that dodrin. I confefs myfelf weary and afhamed of refuting fuch ground- lcfs opinions and furmifes ; but it is a tafk which truth and juf- tice and public happinefs demand. The truth is, the fpot where this fever arofe, is low ground, retaining water to ftagnate after the fpring floods—built upon in a crouded irregular manner— extremely filthy—penetrated by a creek which ha6 been dried and ncglcded, and become the refcrvoir of every unclean thing —in the vicinity is a flaughtcr-houfe, where loads of garbage contribute to render the air foul and noxious. Let any man walk over the ground and examin it with care, as I have done fince the fever, and he will be convinced that no imported fomes was neceffary, in that place, to breed a peftilence. But one of the ftrongeft arguments to prove the domeftic ori- gin of the malady, is, what people rarely confer. Numerous fevers cf the remitting kind, and typhbs mitior, have originated on the fame ground, for feveral years paft 4 and in 1798, two i-dfes of malignant yellow fever—one of which terminated in three days. Thefe fevers marked the predominant ftate of that local atni&f^here, and decide the queftion of domeftic origin. On the 15th of Jury ».tremendous hail ftorm paffed over Con- nedicut fioni the weftward, attended with violent wind and thunder. The ftones and pieces of ice were of various fizes, fiom that of a walrnat to that of a hen's egg. In Gofhen, Corn- wall, New-Hartford, &c. on the weft, and Lebanon, Franklin, Sec. on the eaft of the Connedicut, the grafs, corn and every green thing was injured or deftroyed ; glafs was broken, trees gal^d, and fmall animals killed. The champain country on the Connedicut was lefs injured. This ftorm, unexampled in Con- nedicut, refembles numbeilcfs hail ftorms defcribed in hiftory, as the precurfors and companions of peftilence. END of the FIRST VOLUME. Med. (4iit WZ. xno v.! ^ii iiffi- ■ ffluH(jlil|(l life?'"!