NATIONAL LIBRARY OF MEDICINE Washington Founded 1836 U. S. Department of Health, Education, and Welfare Public Health Serriee Z 0 0 N 0 M I A; OR, The Laws of Organic Life. /f/L^/. PART SECOND. Br ERASMUS DARWIN, m. d* A NEW EDITION WITH An IntroduBory Addrefs> AND A SHORT APPENDIX, By CHARLES CALDWELL, m. d. FELLOW OF THE COLLEGE OF PHYSICIANS OF PHILADELPHIA, MEMBER OF THE AMERICAN PHILOSOPHICAL SOCIETY, ? VOL. I. PHILADELPHIA; PRINTED BY T. DOBSON, AT THE STONE HOUSE NO. 41, SOUTH SECOND STREET. 1797. ZOONOMI A; OR, The Laws of Organic Life. PART II. CONTAINING A CATALOGUE OF DISEASES DISTRIBUTED INTO NATURAL CLASSES ACCORDING TO THEIR PROXIMATE CAUSES, WITH 7HEIR SUBSEQUENT ORDERS, GENERA, AND SPECIES, AND WITH THEIR METHODS OF CURE. Hicc, ut potero, explicabo ; nee tamen, quad Pythius Apollo, certa ut fint et fixa, qaas dixero ; led ut Homunculus unus e multis probabiliora conjedtura. fequens. Cic. Tusc. Disp. 1. i. 9. INTRODUCTORY ADDRESS. T from fever. of infant0 6. Salivatio calida. j. Catarrhus calidus. 8. Expecloratio calida. 9. Exfudatio pone aures. 10. Gonorrhoea calida. 11. Fluor albus calidus. 12. Hamorrhois alba. 13. Serum e veficatorio. 1 a. Perfpiratio fxtida. 15. Crines norji. ------falivation. ------catarrh. ------expectoration. Difcharge behind the ears Warm gonorrhoea. ------fluor albus. White piles. Difcharge from a blifter. Fetid perfpiration. New hairs. GENUS Class I. i. 4.] OF IRRITATION. S GENUS III. With increafed Aclions of the Abforbent Sy/lem. SPECIES. 1. Lingua arida. Dry tongue. 2. Fauces arida. Dry throat. 3. Nares aridi. Dry noftrils. 4. Expefioratio folida. Solid expectoration. 5. Conflipatio alvi. Coftivenefs. 6. Cutis arida. Dry fkin. 7.Urina par dor colorata. Diminifhed coloured urine. 8. Calculusfelleuseticlerus. Gall-ftone and jaundice. 9*-------rents. Stone of the kidney. 10.------+ vefica. Stone of the bladder. 11--------arthriticus. Gout-ftone. 12. Rheumatifmuschronicus. Chronic rheumatifm. 13. Cicatrix vulnerum. Healing of ulcers. 14. Cornea obfufcatio. Scar on the cornea. GENUS IV. With increafed Aclions of other Cavities and Membranes. SPECIES. 1. Niclitatio irritativa. Irritative nictitation. 2. Deglutitio irritativa. Irritative deglutition. 3. Refpiratio et fujfis. Refpiration and cough. 4. Exclufio bilis. Exclufion of the bile. 5. Dcntitio. Toothing. 6. Priapifmus. Priapifm. 7. Difientio mamularum. Diftenfion of the nipples. B 3 8. Defcenfus 6 DISEASES [Class T. 1.5 8. Defcenfus uteri. Defcent of the uterus. 9. Prolapfus ani. Defcent of the rectum. 10. Lumbricus. Round worm. 11. Tania. Tape-worm. 12. Afcarides. Thread-worm. 13. Dracunculus. Guinea-worm. 14. Morpiones. Crab-lice. 15. Pediculi. Lice. GENUS V. With increafed ^c7/o« r of the Organs of Senfe* SPECIES. \ 1. F//kr acrior. Acuter fight. 1. Audit us acrior. ------hearing. 3. Olfaclus acrior. ------fmell. 4. Guflus acrior. ------tafte. 5. Taclus acrior. ------touch. 6. Senfus caloris acrior. ——— fenfe of heat. 7.-----extenftonis acrior .------fenfe of extenfion. 8. Titillatie* Tickling. 9. Pruritus. Itching. 10. Do/or w/mr. Smarting. xi, Confternatio, $urprife. ORDO Class I. 2. 3.] OF IRRITATION. ORDO II. Decreafed Irritation. GENUS I. With decreafed Aclions of the Sanguiferous Syfiem. SPECIES- 1. Febris inirrltativa* Inirritative fever. 2. Parefis inirritativa. ———— debility. 3. Somnus interruptus. Interrupted fleep. 4. Syncope. Fainting. 5. Hamorrhagia venofa. Venous hemorrhage. 6. Hamorrhois cruenta. Bleeding piles. 7. Hamorrhagia renum. g,--------------hepatis. 9, Hamoptoe venofa. 1 o. Palpitatio cordis. 11. Menorrhagia. 12. Dyfmenorrhagia. 13. Lochia nimia. 14. Abortio fpontanea. 15. Scorbutus. 16. Vibiccs. 17. Petechia. ————- from the kidneys. --------from the liver. Spitting of venous blood. Palpitation of the heart. Exuberant menftruation. Deficient menftruation. Too great lochia. Spontaneous abortion. Scurvy. Extravafations of blood. Purple fpots. GENUS II. With decreafed Aclions of the Secerning Syfiem. SPECIES. 1. Frigus febrile. Coldnefs in fevers. — chronicum. —----—- permanent. B 4 2. Pall? DISEASES [Class I. t* 3. 2. Pallor fugitivus. - permanens. 3. Pus parcius. a. Mucus parcior. 5. Urina parcior pallida. 6. Torpor hepaticus. 7. Torpor pancreatis* 8. Torpor renis. 9. Puncla mucofa vultus. 10. Macula cutis fulva. 11. Canities. 12. Callus. 13. Cataracla. 14. lnnutritio ojfium. 15. Rachitis. 16. Spmtf diflortio. 17. Claudicatio coxaria. 18. Spina protuberans* 19. S/>/7za bifida. 30. Defeclus palati. Palenefs fugitive. —.------permanent. Diminifhed pus. Diminiflied mucus. Pale diminifhed urine. Torpor of the liver. Torpor of the pancreas. Torpor of the kidney. Mucous fpots on the face. Tawny blots on the fkin. Grey hairs. Callus. Cataract. Innutrition of the bones. Rickets. Diftortion of the fpine* Lamenefs of the hip. Protuberant fpine. Divided fpine. Defect of the palate. GENUS III. With decreafed Aclions of the Abforbent Syfiem* SPECIES. 1. Mucus fauciumfrigidus. Cold mucus from the throat. 2. Sudor frigidus. -----fweat. 3. Catarrhus frigidus. -----catarrh. 4. Expecloratio frigida. -----expectoration. k. Urina uberior pallida. Copious pale urine. 6. Diarrhoea Class I. z. 3.3 OF IRRITATION. 6. Diarrhoea frigida. 7. Fluor albus frigidufs. 8. Gonorrhoea frigida. 9. Hepatis tumor, 10. Chlorofis. 11. Hydrocele. 12. Hydrocephalus internus. 13. Afcites. 14. Hydrothorax. 15. Hydrops ovarii. 16. Ana/area pulmonum. 17. Obefitas. 18. Splenis tumor. 19. G^w« tawor #/£#/. lo.Bronchocele. 21. Scrophula. 22. Schirrus. 23. ■ raf?/. 24. ■*—-----urethra. 25--------tf/4 26. Lacleorwn inirritahili' tas. 27. Lymphaticorum inirita- bilitath. Cold diarrhecn. -----fluor albus. -----gonorrhoea. Swelling of the liver. Green ficknefs. Dropfy of the vagina teftis. -------of the brain. -------of the belly. -—----of the cheft. -------of the ovary. -------of the lungs. Corpulency. Swelling of the fpleen. White fwelling of the knee. Swelled throat. King's evil. Schirrus. ------- of the rectum. -----— of the urethra. ------- of the throat. Inirritalility of the lacteals. Inirritahili ty of the lym- phatics. GE xS «..'.*> t« DISEASES [Class I. ^^ 4- GENUS IV. With decreafed aclions of other Cavities and Membranes* SPE I. Sit is calida. ----frigida. 2. Efuries. m 3. Naufeaficea. 4. JEgritudo ventricidi. 5. Cardialgia* 6. Arthritis ventriculi. 7. Colica flatulent a. 8. Colica faturnina. 9. Tympanitis. 10. Hypochondriacs. 11. Cepbalaa frigida* 12. Odontalgia. 13. Otalgia. 14. Pleurodyne chronica. 15. Sciatica frigida* 16. Lumbago frigida* 17. Hy/leralgia frigida. 18. Proclalgia frigida. 19. Veficafellea inirritibili- tas et iclerus. C I E S. Thirft warm. -----cold. Hunger. Dry naufea. Sicknefs of ftomach. Heart-burn. Gout of the ftomach. Flatulent colic. Colic from lead. Tympany. Hypochondriacifm. Cold head-ach. Tooth-ach. Ear-ach. Chronical pain of the fide. Cold fciatica. -----lumbago. -----pain of the uterus. -----pain of the rectum. Inirritability of the gall- bladder and jaundice. GENUS Class I. i. 2.] OF IRRITATION. 11 GENUS V. With decreafed Aclions of the Organs of Senfe. SPECIES. 1. Stultitia inirritabilis. 2. Vifus imminutus. 3. Mufca volitantes. 4. Strabifmus. 5. Amaurofis. 6. Auditus imminutus. 7. Olfaclus imminutus. 8. Guflus imminutus. 9. Taclus imminutus. 10. Stupor. Folly from inirritability. Impaired vifion. Dark moving fpecks. Squinting. Palfy of the optic nerve. Impaired hearing. --------fmell. --------tafte. --------touch. Stupor. ORDO in. Retrograde Irritative Motions. GENUS I. Of the Alimentary Canal. SPECIES. 1. Ruminatio. Chewing the cud. 2. Ruclus. Eructation. 3. Apepfia. Indigeftion, water-qualm. 4. Vomitus. Vomiting. 5. Cholera. Cholera. 6. Ileus. Iliac paflion. 7. Globus hyflcricus. Hyfteric ftrangulatiou 8., Vomendi conamen inane. Vain efforts to vomit. 9. Barberig?n \t DISEASES CClass I. 2. 1 9. Bprborigmus. Gurgling of the bowels. 10. Hyfleria. Hy ft eric difeafe. 11. Hydrophobia. Dread of water. GENUS II. Of the Abforbent Syfiem. SPECIES. 1. Catarrhus lymphaticus. Lymphatic catarrh. 2. Salivatio lymphatica. Lymphatic falivation.v 3. Naufea bumida. Moift naufea, 4. Diarrhoea lymphatica* Lymphatic flux. 5. Diarrhoea chylifera. Flux of chyle. 6. Diabates. Diabetes. 7. Sudor lymphaticus* Lymphatic fweat. 8. Sudor aflhmaticus* Aftmatic fweat. 9. Tranjlatio puris. Tranflation of matter. 1 o.---------laclis. •---------of milk. 11.--------urina.---------of urine. GENUS III. Of the Sanguiferous Syfiem. SPECIES. r. Capillarium motus re- Retrograde motion of the trogrefus. capillaries. 2. Palpitatio cordis. Palpitation of the heart. 3. Anhelatio fpafmodica* . Spafmodic panting. CLASS Class 1.1. i.] OF IRRITATION. 13 CLASS I. DISEASES OF IRRITATION. ORDO I. Increafed Irritation. GENUS I. With increafed Aclions of the Sanguiferous Syfiem. The irritability of the whole, or of part, of our fyf- tern is perpetually changing ; thefe vieiflitudes of irri- tability and of inirritability are believed to depend on the accumulation or exhauftion of the fenforial power* as their proximate caufe; and on the difference of the prefent ftimulus, and of that which we had previoufly been accuftomed to, as their remote caufe. Thus a fmaller degree of heat produces pain and inflammation in our hands, after they have been for a time immer- fed in fnow; which is owing to the accumulation of fenforial power in the moving fibres of the cutaneous veflels during their previous quiefcence, when they were benumbed with cold. And we feel ourfelves cold in the ufual temperature of the atmofphere on coming out of a warm room ; which is owing to the exhauftion of fenforial power in the moving fibres of the veflels of the fkin by their previous increafed ac- tivity, into which they were excited by unufual heat. Hence the cold fits of fever are the occaflon of tlie fucceeding hot ones j and the hot fits contribute to occafio\s 14 DISEASES [Class!. *. i. occafion in their turn the fucceeding cold ones. And though the increafe of ftimulus, as of heat, exercife, or diftention, will produce an increafed action of the ftimulated fibres; in the fame manner as it is pro- duced by the increafed irritability which was occa- fioned by a previous defect of ftimulus; yet as the excefles of irritation from the ftimulus of external things are more eafily avoided than the deficiencies of it; the difeafes of this country, except thofe which are the confequences of drunkennefs, or of immode- rate exercife, more frequently begin with torpor than with orgafm ; that is, with inactivity of fome parts, or of the whole of the fyftem, and confequent coldnefs, than with increafed activity, and confequent heat. If the hot fit be the confequence of the cold one, it may be alked if they are proportionate to each other : it is probable that they are, where no part is deftroyed by the cold fit, as in mortification or death. But we have no meafure to diftinguifti this, except the time of their duration ; whereas the extent of the torpor over a greater or lefs part of the fyftem, which occafions the cold fit; or of the exertion which occa- fions the hot one; as well as the degree of fuch tor- por or exertion, are perhaps more material than the time of their duration. Befides this fome mufcles are lefs liable to accumulate fenforial power during their torpor, than others, as the locomotive mufcles com- pared with the capillary arteries; on all which ac- counts a long cold fit may often be followed by a fliort hot one. SPECIES,, Class I. i. i.] OF IRRITATION. >5 SPECIES. i. Febris irritativa. Irritative fever. This is the fynocha of fome writers : it is attended with ftrong pulfe without inflammation; and in this circumftance differs from the febris inirritativa of Clafs I. 2. 1. 1. which is attended with weak pulfe without inflamma- tion. The increafed frequency of the pulfation of the heart and arteries constitutes fever; during the cold fit thefe pulfations are always weak, as the ener- gy of action is then decreafed throughout the whole fyftem; and therefore the general arterial ftrengtli cannot be determined by the touch, till the cold part of the paroxyfm ceafes. This determination is fome- times attended with difficulty; as ftrong and weak are only comparative degrees of the greater or lefs Te- ndance of the pulfation of the artery to the compref- fion of the finger. But the greater or lefs frequency of the pulfations affords a collateral evidence in thofe cafes, where the degree of ftrength is not very diftin- guifhable, which may aflift our judgment concerning it. Since a moderately ftrong pulfe, when the pa- tient is in a recumbent pofture, and not hurried ia mind, feldom exceeds-120 ftrokes in a minute ; where- as a weak one often exceeds 130 in a recumbent po£ ture, and 150 in an erect one, in thofe fevers, which are termed nervous or putrid. See Sect. XII. 1. 4. The increafed frequency of the pulfation of the heart and arteries, as it is occafioned either by exceil or defect of ftimulus, or of fenforial power, exifts botli !•; 16 DISEASES [Class I. i. r. in the cold and hot fits of fever; but when the cold fit ceafes, and the pulfe becomes ftrong and full as well as quick, in confequence of the increafed irritability of the heart and arteries, it conftitutes the irritative fe* ver, or fynocha. It is attended with confiderablc heat daring the paroxyfm, and generally terminates in a quarter of a lunation, without any difturbance of the faculties of tjie mind. See Clafs IV. i. i. 8. M. M. Venefection. Emetics. Cathartics. Cool the patient in the hot fit, and warm him in the cold one. Reft. Torpentia. 2. Ebrietas. Drunkennefs. By the ftimulus of wine or opium the whole arterial fyftem, as well as every other part of the moving fyftem, is excited into mcreafed action. All the fecretions, and with them the production of fenforial power itfelf in the brain, feem to be for a time increafed, with an additional quantity of heat, and of pleafurable fenfation. See Sect. XXI. on this fubject. This explains, why at the commencement of the warm paroxyfm of fome fevers the patient is in greater fpirits, or vivacity; becaufe, as in drunkennefs, the irritative motions are all increafed, and a greater production of fenfation is the confequence, which when in a certain degree, is pleafurable, as in the diurnal fever of weak people. Seft. XXXVI. 3. 1. 3. Hamorrhagia arteriofa. Arterial hemorrhage. Bleeding with a quick, ftrong, and full pulfe. The 2 haemorrhage- Class I. r. i.J OF IRRITATION. i? hemorrhages from the lungs, and from the nofe, are the moft frequent of thefe; but it fometimes happens, that a fmall artery but half divided, or the puncture of a leech, will continue to bleed pertinacioufly. M. M. Venefection. Cathartic with calomel. Di- vide the wounded artery. Bind fponge on the punc- ture. If coffee or charcoal internally ? If air with lefs oxv^en ? 4. Hamoptoe arteriofa. Spitting of arterial blood. Blood fpit up from the lungs is florid, becaufe it has juft been expofed to the influence of the air in its paf- fage through the extremities of the pulmonary ar- tery ; it is frothy, from the admixture of air with it in the bronchia. The patients frequently vomit at the fame time from the difagreeable tidilation of blood about the fauces; and are thence liable to believe, that the blood is rejected from the ftomach. Sometimes an hemoptoe for feveral fucceflive days returns in gouty perfons without danger, and feems to fupply the place of the gouty paroxyfms. Is not the liver always difeafed previous to the hemoptoe, as in feveral other hemorrhages ? See Clafs La. 1. 9. M. M. Venefection, a purge, a blifter, diluents, torpentia; and afterv/ards forbentia, as the bark, the acid of vitriol, and opium. An emetic is faid to flop a pulmonary hemorrhage, which it may effect, as ficknefs dccreafes the circulation, as is very evident in the great ficknefs fometimes produced by top large a dofe of digitalis purpurea. C Dr iS DISEASES [Class I. i. r. Dr. Rufli fays, a table fpoonful or two of common fait is fuccefsful in hemoptoe ; this may be owing to its Stimulating the abforbent fyftcms, both the lym- phatic, and the venous. Should the patient refpire air with lefs oxygen ? or be made fick by whirling round in a chair fufpended by a rope ? One immerfion in cold water, or a fudden fprinkling all over with cold water, would probably ftop a pulmonary hemor* rhage. See Sect. XXVII. i. 5. Hamorrhagia narium. Epiflaxis. Bleeding at , the nofe in elderly fubjects moft frequently attends thofe, whofe livers are enlarged or inflamed by the too frequent ufe of fermented liquors. In boys it occurs perhaps fimply from redundancy of blood; and in young girls fometimes precedes the approach of the catamenia ; and then it fhews a dif- pofition contrary to chlorofis; which arifes from a de- ficiency of red blood. M. M. It is flopped by plunging the head into cold water, with powdered fait haftily diflblved in it; or fomdtimes by lint ftrewed over with wheat flour put up the noftrils; or by a folution of fteel in bran- dy applied to the veflel by means of lint. The cure in other reipects as in hemoptoe ; when the bleeding recurs at certain periods, after venefection, and eva- cuation by calomel, and a blifter, the bark and fteel muft be given, as in intermittent fevers. See Section XXVII. 1. ORDO Class I. 1.2.] OF IRRITATION. ig ORDO I. Increafed Irritation. GENUS II. With increafed Aclions of the Secerning Syfiem. These are always attended with increafe of partial or of general heat; for the fecreted fluids are not Am- ply feparated from the blood, but are new combina- tions ; as they did not previoufly exift as fuch in the blood veflels. But all new combinations give out heat chemically; hence the origin of animal heat, which is always increafed in proportion to the fecre- tion of the part affected, or to the general quantity of the fecretions. Neverthelefs there is reafon to be- lieve, that as we have a fenfe purpofely to diftinguifh the prefence of greater or lefs quantities of heat, as mentioned in Sect. XIV. 6. fo we may have certain minute glands for the fecretion of this fluid, as the brain is believed to fecrete the fenforial power, which would more eafily account for the inftantaneous pro- duction of the blufh of fhame, and of anger. This fubject deferves further investigation. SPECIES. i. Calor febrilis. The heat in fevers arifes from the increafe of fome fecretion, either of the natural fluids, as in irritative fevers; or of new fluids, as in infectious fevers; or of new veflels, as in inflammatory fevers. The pain of heat is a confequence ©f the in- C 2 creafed 20 DISEASES [Class I. 1.2. creafed extenfion or contraction of the fibres expofed to fo great a ftimulus. See Class I. 1.5. 6. 2. Rubor febrilis. Febrile rednefs. When the cold fit of fever terminates, and the pulfations of the heart and arteries become ftrong as well as quick from the increafe of their irritability after thetr late quiefcence, the bbod is impelled forwards into the fine extremities of the arteries, and the anaftomozing capillaries, quicker than the extremities of the veins can abforb and return it to the heart. Hence the pulfe at the wrift becomes full, as well as quick and ftrong, and the /kin glows with arterial blood, and the veins become empty and lefs vifiblc. In elderly people the force of the heart and arte- ries becomes kfs, while the abforbent power of the veins remains the fame; whence the capillary veflels part with the blood, as foon as it is received, and the ikin m confequence becomes paler; it is atfc probable, that in more advanced life fome of the finer branches of the arteries coalefce, and become impervious, and thus add to the opacity of the flcm. 3. Sudor calidus* Warm fweat may be divided into four varieties, according to their remote caufes. Firft, the perfpirable matter is fecreted in as great quantity during the hot fit -of fever, -as towards the •end of tt, when the fweat is feen upon the -ikin. But during -the hot fit the cutaneous abforbents act alfb with increafed energy, and the exhalation is likewiie increafed Class I. i. 2.] Of IRRITATION. 21 increafed by the greater heat of the Skin ; and hence it does not appear in drops on the furface, but is in part reabforbed, and in part diffipated in the atmo- fphere. But as the mouths of the cutaneous abfor- bents are expofed to the cool air or bedclothes ; whilft thofe of the capillary glands, which fecrete the per- fpirable matter, are expofed to the warmth of the cir- culating blood; the former, as foon as the fever-fit begins to decline, lofe their increafed action firft; and hence the abforption of the fweat is diminifhed, whilft the increafed fecretion of it continues for fome hours afterwards, which occafions it to ftand in drops upon the ikin. A* the Ikin becomes cooler, the evaporation of the perfpirable matter becomes lefs, as well as the abforp- tion of it. And hence the diflipation of aqueous fluid from the body, and the confequent thirft, are per- haps greater during the hot fit, than during the fub- fequent fweat. For the fweats do not occur, accord- ing to Dr. Alexander's experiments, till the fkin is cooled from 112 to 108 degrees of heat; that is, till the paroxyfm begins to decline. From this it ap- pears, that the fweats are not critical to the hot fit, any more than the hot fit can be called critical to the cold one; but firaply, that they are the natural con- fequence of the decline of the hot fit, commencing with the decreafed a&ion of the abforbent fyftem, and the decreafed evaporation from the Skin. And from hence it may be concluded, that a fever-fit is not in general an effort of nature to reftore health, as Sy- denham confidered it, but a neceflary confequence of C 3 the 2a DISEASES [Class I. i. 2. the previous torpor ; and that the caufes of fevers would be lefs detrimental, if the fever itfelf could be prevented from exifting ; as appears in the cool treat- ment of the fmall-pox. It muft be noted that the profufe fweats on the /kin are more frequent at the decline of fever-fits than the copious urine, or loofe (tools, which are mentioned be- low ; as the cutaneous abforbents, being expofed to the cool air, lofe their increafed action fooner than the urinary or inteftinal abforbents ; which open into the warm cavities of the bladder and inteftines ; but which are neverthelefs often affected by th^ir fympathy with the cutaneous abforbents. Hence few fevers termi- nate without a moifture of the /kin; whence arofe the fatal practice of forcing fweats by the external warmth of air or bedclothes in fevers; for external warmth increafes the action of the cutaneous capilla- ries more than that of the other fecerning veflels; becaufe the latter are habituated to 98 degrees of heat, the internal warmth of the body ; whereas the cutaneous capillaries being nearer the furface are ha^ bitually kept cooler by the contact of the external air. Sweats thus produced by heat in confined rooms are ftill more detrimental ; as the air becomes then not only deprived of a part of its oxygene by fre- quent refpiration, but is loaded with animal effluvia as well as with moifture, till it can receive no more; and in confequence, while the cutaneous fecretion Stands upon the ikin in drops for want of exhalation, £he lungs are expofed to an infalubrious atmofphere. I do Class I. i. 2.] OF IRRITATION. 23 I do not deny, that fweating may be fo managed as to be ferviceable in preventing the return of the cold paroxyfm of fevers ; like the warm bath, or any other permanent ftimulus, as wine, or opium, or the bark. For this purpofe it Should be continued till paft the time of the expected cold fit, fupported by moderate dofes of wine-whey, with fpirit of hartfhorn, and mo- derate degrees of warmth. Its falutary effect, when thus managed, was probably one caufe of its having been fo much attended to; and the fetid Smell, which when profufe is liable to accompany it, gave occafion to the belief, that the fuppofed material caufe of the difeafe was thus eliminated from the circulation. When too great external heat is applied, the fyftem is weakened by excefs of action, and the torpor which caufes tlie cold paroxyfm recurs fooner and more vio- lently. For though fome flimuii, as of opium and alcohol, at the fame time that they exhauft the fenfo- rial power by promoting increafe of fibrous action, may alfo increafe the production or fecretion of it in the brain, yet experience teaches us, that the exhauf- tion far out-balances the increafed production, as is evinced by the general debility, which fucceeds in- toxication. In refpect to the fetor attending copious continued fweats, it is owing to the animalized part of this fluid being kept in that degree of warmth, which moft fa- vours putrefaction, and not fuffered to exhale into the atmofphere. Broth, or other animal mucus, kept in fimilar circumftances, would in the fame time acquire C 4 a putrid .24 DISEASES [Class I. i. 2. a putrid fmell; yet has this error frequently produceH miliary eruptions* and increafed every kind of inflam- matory or fenfitive fever. The eafc, which the patient experiences during Sweating, if it be not produced by much external heat, is fimilar to that of the warm bath j which by its Sti- mulus applied to the cutaneous ve/Tels* which are ge- nerally cooler than the internal parts of the fyftem, excites them into greater action ; and pleafurable fen- fation is the confequence of thefe increafed actions of the veffels of the ikin. From considering all thefe circumftances, it appears that it is not the evacuation by fweats^ but the continued Stimulus, which caufes and fupports thofe fweats, which is ferviceable in pre- venting the returns of fever-fits. And that fweats too Jong continued, or induced by too great Stimulus" of warmth, clothes, or medicines^ greatly injure the pa- tient by increafing inflammation, or by exhaufting the fenforial power. See Clafs I. 1. 2. 14, Secondly, The fweats produced by exercife or labour are of the warm kind ; as they originate from the in- creafed action of the capillaries of the fkinj owing to their being more powerfully ftimulated by the greater velocity of the blood, and by a greater quantity of it pafling through them in a given time. For the blood during violent exercife is carried forwards by the action of the mufcles fafter in the arteries^ than it can be taken up by the veins ; as appears by the red- nefs of the Skin. And from the confequent fweats, it ?.s evinced, that the fecretory veflels of the /kin du^ ring Class I. i. 2.] OF IRRITATION. 25 ring exercife pour out the perfpirable matter fafter, than the mouths of the abforbent veflels can drink it up. Which mouths are not expofed to the increafed mufcular action, or to the Stimulus of the increafed velocity and quantity of the blood, but to the ccoS air. Thirdly, The increafed fecretion of perfpirable mat- ter occafioned by the Stimulus of external heat be- longs likewife to this place \ as it is caufed by the in- creafed motions of the capillary Veflels 5 which thus feparate from the blood more perfpirable matter, than the mouths of their correspondent abforbent veflels can take up ; though thefe al fo are Stimulated by ex- ternal heat into more energetic action-. If the air be Stationary, as in a fmall room, or bed with fclofed cur- tails, the fweat Stands in drops on the ikin for want of a quicker exhalation proportioned to the quicker fecretion. A fourth variety of warm perfpiration is that occa- fioned by Stimulating drugs, of which opium and alco- hol are the moft powerful; and next to thefe the fpices, volatile alkali, and neutral falts, efpecially fea fait; that much of the aqueous part cf the blood is diflipated by the ufe of thefe drugs,, is evinced by the great thirft, which occurs a few hours after the ufe of them-. See Art. III. 2. 12. and Art. HI. 2. 1. We may from hence underftandj that the increafe of this Secretion of perfpirable matter by artificial means, muft be followed by debility and emaciation. When this is done by taking much fait, or faltcd meat, the 26 DISEASES [Class I. 1. 2. the fea-fcurvy is produced; which confifts in the inir- ritability of the bibulous terminations of' the veins arifing from the capillaries; fee Clafs I. 2. i. 14. The fcrophula, or inirritability of the lymphatic glands, feems alfo to be occafionally induced by an excefs in eating fait added to food of bad nourifh- ment. See Clafs I. 2. 3. 21. If an excefs of perfpi- ration is induced by warm or Stimulant clothing, as by wearing flannel in contact with the ikin in the fummer months, a perpetual febricula is excited, both by the preventing the accefs of cool air to the /kin, and by perpetually goading it by the numerous and hard points of the ends of the wool; which when applied to the tender /kins of young children, frequently produce the red gum, as it is called ; and in grown people, either an eryfipelas, or a miliary eruption, attended with fever. See Clafs II. 1. 3. 12. Shirts made of cotton or calico Stimulate the Ikin too much by the points of the fibres, though lefs than flannel; whence cotton handkerchiefs make the nofe fore by frequent ufe. The fibres of cotton are, I fuppofe, ten times fhorter than thofe of flax, and the number of points in confequence twenty times the number; and though the manufacturers finge their calicoes on a red-hot iron cylinder, yet I have more than once feen an eryfipelas induced or increa- fed by the ftimulus of calico, as well as of flannel. The increafe of perfpiration by heat either of clothes, or of fire, contributes much to emaciate the body ; as is well known to jockeys; who, when they are CtAss I. i. 2.] OF IRRITATION. 27 are a Stone or two too heavy for riding, find the quickeft way to leflen their weight is by Sweating themfelves between blankets in a warm room; but this likewife is a practice by no means to be recom- mended, as it weakens the fyftem by the excefs of fo general a ftimulus, brings on a premature old age, and fhortens the fpan of life; as may be further deduced from the quick maturity, and fliortnefs of the lives, of the inhabitants of Hindoftan, and other tropical climates. M. Buftbn made a curious experiment to fliew this circumftance. He took a numerous brood of the but- terflies of filkworms, fome hundreds of which left their eggs on the fame day and hour; thefe he divi- ded into two parcels ; and placing one parcel in the fouth window, and the other in the north window of his houfe, he obferved, that thofe in the colder fitua- tion lived many days longer than thofe in the warmer one. From thefe obfervations it appears, that the wearing of flannel clothing next the /kin, which is now fo much in fafhion, however ufeful it may be in the winter to thofe, who have cold extremities, bad digeftions, or habitual coughs, muft greatly debilitate them, if worn in the warm months, producing fevers, eruptions, and premature olcj age. See Sect. XXXVII. £. Clafs I. 1. 2. 14. Art. III. 2. 1. 4. Urina uberior colorata. Copious coloured urine. towards the end of fever-fits a large quantity of high .0Loured urine is voided, the kidneys continuing to act ftrongly, 28 DISEASES [Class I. i. 2. Strongly', after the increafed action of the abforbents of the bladder is fomewhat diminifhed. If the abforb- ents" continue alfo to act ftrortgly, the urine is higher coloured, and fo loaded as to depofit, when cool, an Earthy fediment, erroneOufly thought to be the mate- rial caufe of the difeafe; but is fimply owing to the fecretion of the kidneys being great from their in- creafed action ; and the thinner parts of it being ab- sorbed by thfc increafed action of the lymphatics, which are fpread very thick on the neck of the blad- der ; for the urine, as well as perhaps all the other fecreted fluids, is produced from the kidneys in a very dilute State ; as appears in thofe, who from the Stimu- lus of a ftone, or other caufe, evacuate their urine too frequently ; which is then pale from its not having remained in the bladder long enough for the more aqueous part to have been reabforbed. The general ufe of this urinary abforption to the animal ceconomy is evinced from the urinary bladders of fifh, which would otherwife be unncceffary. High coloured urine m large quantity fhews only, that the fecreting veffels bf the kidneys, and the abforbents of the bladder, have acted with greater energy. When there is much earthy fediment, it lhew3, that the abforbents have a&ed proportionally Stronger, and have confequently left the urine in a lefs dilute State. In this urine the tranfparent fediment or cloud is mucous; the opake fediment is probably coagulablc lymph from the blood changtd by an animal or chemical procefs. The float- iag &um is oil. The angular concretions to the fides #f Class I. i. 2.] OF IRRITATION. 29 of the pot, formed as the urine cools, is microcofmic fait. Does the adhefive blue matter on the fides of the glafs, or the blue circle on it at the edge of the upper furface of the urine, confift of Pruflian blue ? 5. Diarrhoea calida. Warm diarrhcea. This fpe- cies may be divided into three varieties deduced from their remote eaufes, under the names of diarrhoea fe- brilis, diarrhoea crapulofa, and diarrhcea infantum. The febrile diarrhcea appears at the end of fever-fits, and is erroneoufly called critical, like the copious urine, and the fweats ; whereas it arifes from the in- creafed action of thofe fecerning organs, which pour their fluids into the inteftinal canal (as the liver, pancreas, and mucous glands), continuing longer than the increafed action of the inteftinal abforbents. In this diarrhcea there is no appearance of curdled chyle in the Stools, as occurs in cholera. I. 3. 1.5. The diarrljcza crapulofa, or diarrhcea from indigef- tion, occurs when too great a quantity of food or li- quid has been taken ; which not being completely di- gested, Stimulates the inteftines like any other extra- neous acrid material; and thus produces an increafe of the fecretions into them of mucus, pancreatic juice, and bile. When the contents of the bowels are ftil! more Stimulant, as when draftie purges, or very pu- trescent diet, have been taken, a cholera is induced. See Sect. XXIX. 4. The diarrhcea infantum, or diarrhcea of infants, h generally owing to too great acidity in their bowels. Milk jo DISEASES [Class I. I. r. Milk is found curdled in the Stomachs of all animals, old as well as young, and even of carnivorous ones, as of hawks. (Spallanzani.) And it is the gaftric juice of the calf, which is employed to curdle milk in the procefs of making cheefe. Milk is the natural food for children, and muft curdle in their Stomachs previous to digeftion; and as this curdling of the milk deftroys a part of the acid juices of the ftomach, there is no reafon for difcontinuing the ufe of it, though it is occafionally ejected in a curdled Slate. A child of a week old, which had been taken from the breaft of its dying mother, and had by fome uncommon error been fuffered to take no food but water-gruel, be- came fick and griped in twenty-four hours, and was convulfed on the fecond day, and died on the third! When all young quadrupeds, as well as children, have this natural food of milk prepared for them, the ana- logy is fo ftrong in favour of its falubrity, that a per- fon fhould have powerful teftimcny indeed of its disa- greeing, before he advifes the difcontinuance of the ufe of it to young children in health, and much more fo in ficknefs. The farmers lofe many of their calves, which are brought up by gruel, or gruel and old milk; and among the poor children of Derby, who are thus fed, hundreds are ftarved into the fcrophula, and either peri/h, or live in a State of wretched debility. When young children are brought up without a breaft, they Should for the firft two months have no food but new milk ; fince the addition of any kind of bread or flour is liable to ferment, and produce too nnch Class I. i. 2.] OF IRRITATION. $1 much acidity ; as appears by the confequent diarrhcea with green dejections and gripes; the colour is owing to a mixture of acid with the natural quantity of bile, and the pain to its ftimulus. And they mould never be fed as they lie upon their backs, as in that pofture they are neceflitated to fwallow all that is put Into their mouths; but when they are fed, as they are fit- ting up, or raifed up, when they have had enough, they can permit the reft to run out of their mouths. This circumstance is of great importance to the health of thofe children, who are reared by the fpoon, fince if too much food is given them, indigeftion, and gripes, and diarrhcea, is the confequence ; and if too little, they become emaciated ; and of this exact quan- tity their own palates judge the belt. M. M. In this laft cafe of the diarrhcea of children, the food fliould be new milk, which by curdling de- ftroys part of the acid, which coagulates it. Chalk about four grains every fix hours, with one drop of fpirit of hartfhorn, and half a drop of laudanum. But a blifter about the fize of a Shilling is of the greateft fervice by reftoring the power of digeftion. See Ar- ticle in. 2. i. in the fubfequent Materia Medica. 6. Salivatio calida. Warm falivation. Increafed fecretion of faliva. This may be effected either by ftimulating the mouth of the gland by mercury taken internally ; or by ftimulating the excretory duct of the gland by pyrethrum, or tobacco; or fimply by the movement of the mufcles, which lie over the gland, as 3i DISEASES [Class I. i. 2. as in mafticating any taftelefs fubftance, as a lock of wool, or maftic. In about the middle of nervous fevers a great fpitting of faliva fometimes occurs, which has been thought cri- tical ; but as it continues fometimes two or even three weeks without the relief of the patient, it may be concluded to arife from forae accidental circumftance* perhaps not unumilar to the hyfteric ptyalifras men- tioned in Clafs I. 3. 2. 2. See Sect. XXIV. M. M. Cool air, diluents, warm bath, evacuations. 7. Catarrhus calidus. Warm catarrh. Confifts in an increafed fecretion of mucus from the noftrils with- out inflammation. This difeafe, which is called a cold in the head, is frequently produced by cold air acting for fome time on the membranes, which line the nof- trils, as it paffes to the lungs in refpiration. Whence a torpor of the a&ion of the mucous glands is firft introduced, as in I. 2. 3. 3. and an orgafm or increafed action fucceeds in confequence. Afterwards this or- gafm and torpor are liable to alternate with each other for fome time like the cold and hot fits of ague, attended with deficient or exuberant fecretion of mu- cus in the noftrils. At other times it arifes from reverfe fympathy with fome extenfive parts of the Skin, which have been ex- pofed too long to cold, as of the head, or feet. In confequence of the torpor of thefe cutaneous capilla- ries thofe of the raucous membrane of the noftrils act with greater energy by reverfe fympathy ; and thence J fecretc Cla'ssI. i.2.] • OF IRRITATION. 33 fecrete more mucus from the blood. At the fame time the abforbents, acting alfo with greater energy by their reverfe fympathy with thofe of fome diftant part of the fkin, abforb the thinner parts of the mucus more haftily; whence the mucus is both thicker and in greater quantity. Other curious circumftances at- tend this difeafe ; the membrane becomes at times fo thickened by its increafed action in fecreting the mu- cus, that the patient cannot breathe through his nof- trils. In this fituation if he warms his whole /kin fuddenly by fire or bed-clothes," or by drinking warm tea, the increafed action of the membrane ceafes by its reverfe fympathy with the ikin ; or by the retrac- tion of the fenforial power to other parts of the fyf- tem ; and the patient can breathe again through the noftrils. The fame fometimes occurs for a time on going into the cold air by the deduction of heat from the mucous membrane, and" its confequent inactivity or torpor. Similar to this when the face and breaft have been very hot and red, previous to the eruption of the fmall-pox by inoculation, and that even when expofed to cool air, I have obferved the feet have been cold; till on covering them with warm flannel, as the feet have become warm, the face has cooled, See Sect. XXXV. 1. 3. Clafs II. 1. 3. 5. IV. 2. 2. 10. IV. 1. 1. 5. M. M. Evacuations, abstinence, oil externally on the nofe, warm diluent fluids, warm flioes, warm night- cap. D 8. Expee* 34 DISEASES [Class I. i. ». 8. Expecloratio calida. Warm expectoration con- fifts of the increafed fecretion of mucus from the mem- brane, which lines the bronchia?, or air-cells of the lungs, without inflammation. This increafed mucus is ejected by the action of coughing, and is called a cold, and refembles the catarrh of the preceding article ; with which it is frequently combined. M. M. Inhale the fteam of warm water, evacua- tions, warm bath, afterwards opium, forbentia. 9. Exfudatio pone aures* A difcharge behind the ears. This chiefly affects children, and is a morbid fe- cretion ; as appears from its fetor; for if it was owing to defect of abforption, it would be falfne, and not fetid ; if a morbid action has continued a confider- able time, it fhould not be flopped too fuddenly ; fince in that cafe fome other morbid action is liable to fuc- cced in its Stead. Thus children are believed to have had cholics, or even convulfions, confequen? to the too fudden healing of thefe morbid effufions behind their ears. The rationale of this is to be explained from a medical fact, which I have frequently obferved ; and that is, that a blifter on the back greatly ftrengthens the power of digeftion, and removes the heart-burn in adults, and green ftools in children. The ftimulus of the blifter produces fenfation in the veSTels of the Skin -7 with this additional fenforial power thefe veflels act more Strongly; and with thefe the veSTels of the in- ternal membranes of the ftomach and bowels act with greater energy from their direct fympathy with them* Nov* Class I. i. 2.] OF IRRITATION. 35 Now the acrid difcharge behind the ears of children produces fenfation on that part of the ikin, and fo far acts as a fmall blifter. When this is fuddenly flopped, a debility of the digeftive power of the ftomach Suc- ceeds from the want of this accuftomed ftimulus, with flatulency, green ftools, gripes, and fometimes confe- quent convulfions. See Clafs II. 1. 5. 6. and II. 1. 4. 6. M. M. If the matter be abforbed, and produces Swelling of the lymphatics of the neck, it fhould be cured as foon as poffible by dufting the part with white lead, cerufla, in very fine powder; and to pre- vent any ill confequence an iflue Should be kept for about a month in the arm ; or a purgative medicine fhould be taken every other day for three or four times, which Should confift of a grain of calomel, and three or four grains of rhubarb, and as much chalk. If there be no appearance of abforption, it is better only to keep the parts clean by wafhing them with warm water morning and evening ; or putting fuller's earth on them; efpecially till the time of toothing is paft. The tinea, or fcald head, and a leprous erup- tion, which often appears behind the ears, are differ- ent difeafes. 1 o. Gonorrhoea calida. Warm gleet. Increafed difcharge of mucus from the urethra or proftate gland without venereal defire, or venereal infection. See Clafs I. 2. 3. 8. D 2 M. M. Can- 36 DISEASES [Class I. I. 2. M. M. Cantharides, balfams, rhubarb, blifter ia perineum, cold bath, injections of metallic falts, flan- nel fhirt, change of the form of the accuftomed chair or Saddle of the patient. 11. Fluor alius calidus. Warm fluor albus. In- creafed fecretion of mucus in the vagina or uterus without venereal defire or venereal infection. It is diftinguiflied from the fluor albus frigidus by the in- creafed fenfe of warmth in the part, and by the great- er opacity or fpiifitude of the material difcharged ; as the thinner parts are reabforbed by the mcreafed ac- tion of the abforbents, along with the Saline part, whence no Smarting or excoriation attends it. M. M. Mucilage, as ifinglafs, hartfliorn jelly, gum arable. Ten grains of rhubarb every night. Callico or flannel Shift, opium, balfams. See Clafs I. 2. 3. 7. 12. Hamorrhois alba. White piles. An increafed difcharge of mucus from the rectum frequently mifta- ken for matter ; is faid to continue a few weeks, and recur like the bleeding piles ; and to obey lunar in- fluence. See Clafs I. 2. 1. 6. M. M. Abftinence from vinous fpirit. Balfam of copaiva. Spice fwallowed in large fragments, as ten or fifteen black pepper-corns cut in half, and taken after dinner and fupper. Ward's pafte, confifting of black pepper and the powdered root of Helenium Enuku 13. Serum Class I. i. 2.] OF IRRITATION. 3? 13. Serum e veficatorio* Difcharge from a blifter. The excretory ducts of glands terminate in mem- branes, and are endued with great irritability, and ma- ny of them with fenfibility; the latter perhaps in con- quence of their facility of being excitable into great action; inftances of this are the terminations of the gall-duct in the duodenum, and of the falivary and la- chrymal glands in the mouth and eye ; which produce a greater fecretion of their adapted fluids, when the ends of their excretory ducts are flimulated. The external ikin confifts of the excretory duets of the capillaries, with the mouths of the abforbents 5 when thefe are Stimulated by the application of can- iharides, or by a Slice of the frefh root of bryonia alba bound on it, the capillary glands pour an increafed quantity of fluid upon the Skin by their increafed action; and the abforbent veflels imbibe a greater quantity of the more fluid and faline part of itj whence a thick mucous or ferous fluid is depofited be- tween the ikin and cuticle. 14. Perfpiratio foetidd. Fetid perfpiration. The ufes of the perfpirable matter are to keep the ikin foft and pliant, for the purpofes of its eafier flexibi- lity during the activity of our limbs in locomotion, and for the prefervation of the accuracy of the fenfe of touch, which is diffufed under the whole furface of it to guard us againft the injuries of external bo- dies ; in the fame manner as the fecretion of tears is defigned to preferve the cornea of the eye moift, and D3 in 38 DISEASES [Class I. 1. 2. in confequence tranfparent; yet has this cutaneous mucus been believed by many to be an excrement; and I know not how many fanciful theories have been built on its fuppofed obflruction. Such as the origin of catarrhs, coughs, inflammations, eryfipelas, and herpes. To all thefe it may be fufficient to anfwer, that the ancient Grecians oiled themfelves all over; that fome nations have painted themfelves all over, as the Picts of this ifland ; that the Hottentots fmear themfelves all over with greafe. And laftly, that many of our own heads at this day are covered with the flour of wheat and the fat of hogs, according to the tyranny of a filthy and wafteful fafhion, and all this without ^convenience. To this muft be added the ftrict ana- logy between the ufe of the perfpirable matter and the mucous fluids, which are poured for fimilar pur- pofes upon all the internal membranes of the body; and befides its being in its natural State inodorous; which is not fo with the other excretions of feces, or of urine. In fome constitutions the perfpirable matter of the lungs acquires a difagreeable odour ; in others the axil- la, and in others the feet, emit difguftful effluvia ; like the fecretions of thofe glands, which have been called odorifere.; as thofe, which contain the caftor m the beaver, and thofe within the rectum of dogs, the mu- cus of which has been fuppofed to guard them againft the great coftivenefs, which they are liable to in hot Cummers; and which has been thought to occafion canine Class I. i. 2.] OF IRRITATION. 319. canine madnefs, but which, like their white excre- ment, is more probably owing to the deficient fecre- tion of bile. Whether thefe odoriferous particles at- tend the perfpirable matter in confequence of the in« creafed action of the capillary glands, and can pro* perly be called excrementitious; that is, whether any thing is eliminated, which could be hurtful if retain- ed ; or whether they may only contain fome of the effential oil of the animal; like the fmell, which ad- heres to one's hand on Stroking the hides of fome dogs; or like the effluvia, which is left upon the ground, from the feet of men and other creatures; and is perceptible by the nicer organs of the dogs, which hunt them, may admit of doubt. M. M. Wafh the parts twice a day with foap and water ; with lime water; cover the feet with oiled fiik focks, which muft we wafhed night and morning. Cover them with charcoal recently made red hot, and beaten into fine powder and Sifted, as foon as cold, and kept well corked in a bottle, to be warned off, and renewed twice a day. Internally rhubarb grains vi. or viii. every night, fo as to procure a ftool or two extraordinary every day, and thus by increafing one evacuation to decreafe another. Cool drefs, diluting liquids ? 15. Crines ncvi* New hairs, ^he black points on the faces of fome people confift of mucus, which is become vifcid, and which adheres in the excretory ducts of the glands of the ikin j as defcribed in Clafs D 4 I- 2, a.-p. 4© DISEASES [Class I. i. 2. I. 2. 2. 9. and which maybe prefled out by the fin- gers, and rcfembles little worms. Similar to this would feem the fabrication of Silk, and of cobweb by the filk worm and fpider ; which is a fecreted matter preflfed through holes, which are the excretory ducts of glands. And it is probable, that the production of hair on many parts of the body, and at different periods of life, may be effected by a Similar procefs; and more efpecially as every hair may be confidered as a Slender flexible horn, and is an appendage of the ikin. See Sect. XXXIX. 3. 2. Nov/ as there is a fenfitive fympathy between the glands, which fecrete the femen, and the throat, as appears in the mumps; fee Hydrophobia, Clafs IV. 1. 2. 7, and Parotitis, Clafs IV, 1, 2. 19, the growth of the beard at pu- berty feems to be caufed by the greater action of the cutaneous glands about the chin and pubes in confe- quence of their fympathy with thofe of the teftes. But this does not occur to the female fex at their time of puberty, becaufe the fenfitive fympathy in them feems to exift between the fubmaxillary glands, and the pectoral ones; which fecrete the milk, and afford pleafure both by that fecretion, and by the erection of the mamule, or nipples; and by delivering the milk into the mouth of the child; this fenfitive fym- pathy of the pectoral and fubmaxillary glands in wo- men is alfo obfervable in the Parotitis, or mumps, as above referred to, When hairs grow on the face or arms fo as to be difagreeable, they may be thus readily removed with- ... . , out Class I. 1.2.] «F IRRITATION. 4, out pain or any ill confequence. Warm the ends of a pair of nippers or forceps, and flick on them a little rofin, or burgundy pitch; by thefe means each fingle hair may be taken fail hold of; and if it be then plucked off" flowly, it gives pain; but if plucked off fuddenly, it gives no pain at all; becaufe the vis iner- tie of the part of the Skin, to which it adheres, is not overcome ; and it is not in confequence feparated from the cellular membrane under it. Some of the hairs may return, which are thus plucked off, or others may be induced to grow near them; but in a little time they may be thus fafely deftroyed ; which is much to be preferred to the method faid to be ufed in Turn- key to eradicate hair; fuch as a mixture of orpiment and quick lime; or of liver of fulphur in folution; which injure the ikin, if they are not very nicely ma- naged ; and the hair is liable to grow again as after Shaving ; or to become white, if the roots of it have been much inflamed by the caufticity of the applica- tion. See Clafs I. 2. 2. 11. on grey hairs. ORDO *yi DISEASES [ClassI. i. 3. ORDO I. Increafed Irritation* GENUS III. With increafed Aclions of the Abforbent Syfiem. These are not attended with fo great increafe of heat as in the former genus, becaufe the fluids pro- bably undergo lefs chemical change in the glands of the abforbent fyftem ; nor are the glands of the ab- forbent veflels fo numerous or fo extenfive as thofe of the fecerning ones. Yet that fome heat is pro- duced by the increafed action of the abforbents ap- pears from the greater general warmth of the ikin and extremities of feeble patients after the exhibition of the Peruvian bark, and other medicines of the ar- ticle Sorbentia. SPECIES. 1. Lingua arida. Dry tongue occurs in thofe fe- vers, where the expired air is warmer than natural; and happens to all thofe, who fleep with their mouths open; the currents of air in refpiration increafing the evaporation. There is alfo a drynefs in the mouth from the increafed action of the abforbent veflels, when a floe or a crab-apple is mafticated ; and after the perfpiration has been much increafed by eating fait or fpice, or after other copious fecretions; as after drunkennefs, cathartics, or fever fits, the mucus of the mouth becomes vifcid, and in fmall quantity, from Class I. i. 3.] OF IRRITATION. 43 from the increafed abforption, adhering to the tongue like a white Hough. In the diabetes, where the thirft is very great, this Slough adheres riTore pertina- cioufly, and becomes black or brown, being coloured after a few days by our aliment or drink. The infpif- fated mucus on the tongue of thofe, who fleep with their mouths open, is fometimes reddened as if mixed with blood, and fometimes a little blood follows the expuition of it from the fauces owing to its great ad- hefion. When this mucus adheres long to the pa- pille of the tongue, the faliva, which it contains in its interftices, like a fponge, is liable to become pu- trid, and to acquire a bitter tafte, like other putrid animal fubftances ; which is generally mistaken for an indication of the prefence of bile. M. M. Warm fubacid liquids. See Clafs I. 2. 5. 8. 2. Fauces arida. Dry throat. The expuition of a frothy mucus with great and perpetual hawking occurs in hydrophobia, and is very diftrefling to the patient; which may be owing to the increafed irri- tability or fenfibility of the upper part of the cefo- ph'agus, which will not permit any fluid to reft on it. It affects fome people after intoxication, when the lungs remain Slightly inflamed, and by the greater heat of the air in expiration the mucus becomes too haftily evaporated, and is expectorated with difficulty in the State of white froth. I knew a perfon, who for twenty years always waked with his tongue and throat quite dry; fo that he 4^ DISEASES [Class I. i. 3. he was neceflitated to take a fpoonful of water, as foon as he awoke; otherwife a little bloojd always followed the forcible expuition of the indurated mu- cus from, his fauces. See Clafs II. 1. 3. 17. M. M. Steel-fprings fixed to the night-cap fo as to fufpend the lower jaw and keep it clofed; or fprings of elaftic gum. Or a pot of water fufpend- ed over the bed, with a piece of lift, or woollen cloth, depending from it, and held in the mouth; which will act like a fyphon, and flowly fupply moif- ture, or barley water fhould be frequently fyringed into the mouth of the patient. 3. Flares aridi. Dry noftrils with the mucus har- dening upon their internal furface, fo as to cover them with a kind of ikin or fcale, owing to the in- creafed action of the abforbents of this membrane; or to the too great drynefs of the air, which paffes into the lungs; or too great heat of it in its expi- ration. When air is fo dry as to lofe its tranfparcncy ; as when a tremulous motion of it can be feen over corn fields in a hot Summer's day; or when a dry mift, or want of transparency of the air, is vifible in very hot weather; the fenfe of fmell is at the fame time imperfect from the drynefs of the mem> brane, beneath which it is fpread. 4. Expecloratio folida. SoKd expectoration. The mucus of the lungs becomes hardened by the increa- fed Class I. i. 3.] OF IRRITATION. 45 fed abforption, fo that it adheres and forms a kind of lining in the air-cells, and is fometimes fpif up in the form of branching veSTels, which are called polypi of the lungs. See Tranfaet. of the College, London. There is a rattling or wheezing of the breath, but it- is not at firft attended with inflammation. The Cynanche trachealis, or Croup, of Dr. Cullen, or Angina polypofa of Michaelrs, if they differ from the peripneumony of infants, feem to belong to this genus. When the difficulty of refpiration is great, venefection is immediately neceflary, and then an eme- tic, and a blifter. And the child fhould be kept nearly upright in bed as much as may be. See Tonfillitis, Clafs IL 1. 3. 3. M. M. Diluents, emetks, eflence of antimony, foe- tid gums, onions* warm bath for half an hour every day for a month. Inhaling the fleam of water, with ©r without volatile alkali. Soap. 5. Conflipatio- alvi. Coftivenefs from increafed ac- tion of the inteftinal abforbents. The feces are har- dened in lumps called fcybala; which are fometimes obliged to be extracted from the rectum with a kind of marrow fpoon. This is faid to have happened from the patient having taken much raft of iron. The mucus is alfo hardened fo as to line the intef- tines, and to come away in Skins, rolled up as they pafs along, fo as to refemble worms, for which they are frequently miftaken ; and fometimes it is evacua- ted in Still larger pieces, fo as. to counterfeit the form of 46 DISEASES [Class I. 1.3, of the inteftines, and has been miftaken for a por- tion of them. Balls of this kind, nearly as heavy as marble, and confiderably hard, from two inches to five in diameter, are frequently found in the bowels of horfes. Similar balls found in goats have been called Bezoar. M. M. Cathartics, diluents, fruit, oil, foap, Sul- phur, warm bath. Sprinkling with cold water, cool clothing. See Clafs I. 2. 4. 18. 6. Cutis arida. Dry Skin. This dry ikin is not attended with coldnefs as in the beginning of fever- fits. Where this cutaneous abforption is great, and the fecreted material upon it vifcid, as on the hairy fcalp, the ikin becomes covered with hardened mucus; which adheres fo as not to be eafily removed, as the fcurf on the head; but is not attended with inflamma- tion like the Tinea, or Lepra. The moifture, which appears on the ikin beneath refinous or oily platters, or which is feen to adhere to fuch plafters, is owing to their preventing the exhalation of the perfpirable matter, and not to their increafing the production of it, as fome have idly imagined. M. M. Warm bathing, oil externally, oil-ikin gloves, refinous plafters. Wax. 7. Urina parca colorata. Diminifhed urine, which is high coloured, and depofits an earthy fediment, when cold, is owing to the great action of the urinary abforbents. See Clafs I. 1. 2. 4. In fome dropfie« th^ Class I. i. 3.I OF IRRITATION. 47 the cutaneous abforbents are paralytic, a3 well as thofe opening into the cellular membrane ; and hence, no moifture being acquired from the atmofphere, or from the cellular membrane, great third is excited; and great abforption from all parts, where the ab- forbents are ftill capable of action. Hence the urine is in very fmall quantity, and of deep colour, with copi- ous fediment; and the kidneys are erroncoufly blamed for not doing their office; ftimulant diuretic medi- cines are given in vain; and very frequently the un- happy patient is reftrained from quenching his thirft, and dies a martyr to falfe theory. M. M. Diluent liquids, and warm bathing, are the natural cure of this fymptom ; but it generally at- tends thofe dropfies, which are feldom curable ; as they are owing to a paralyfis both of die cutaneous and cellular lymphatics. 8. Calculus felleus. Gall-ftone. From the too hafty abforption of the thinner parts of the bile, the remainder is left too vifcid, and cryftallizes into lumps; which, if too large to pafs, obstruct the duc- tus choledochus, producing pain at the pit of the Sto- mach, and jaundice. When the indurated bile is not harder than a boiled pea, it may pafs through the bile-duct with difficulty by changing its form; and thus gives thofe pains, which have been called fpafms of the Stomach ; and yet thefe vifcid lumps of bile may afterwards diflolve, and not be vifible among the fe- ces. In 4$ DISEASES [Class I. 1.3, 111 two inftances I have feen from thirty to fifty gall-Hones voided after taking an oil vomit as below. They were about the fize of peas, and diftinguifhable when dry by their being inflammable like bad wax, when put into the flame of a candle. For other caufes of jaundice, fee Clafs I. 2. 4. 19. M. M. Diluents, daily warm bathing. Ether mix- ed with yolk of egg and water. Unboiled acrid ve- getables, as lettuce, cabbage, muftard, and crefles. When in violent pain, four ounces of oil of olives, or of almonds, Should be fwallowed ; and as much more in a quarter of an hour, whether it Slays or not. The patient fhould lie on the circumference of a large barrel, firft on one fide, and then on the other. Elec- tric fhocks through the gall-duct. Factitious Selter water made by diflblving one dram of Sal Soda in a pint of water; to half a pint of which made luke- warm add ten drops of marine acid ; to be drank as foon as mixed, twice a day for fome months. Opium muft be ufed to quiet the pain, if the oil does not Succeed, as two grains, and another grain in half an hour if neceflary. See Clafs IV. 2. 2. 4. 9. Calculus renis. Stone of the kidney. The pain in the loins and along the courfe of the ureter from a ftone is attended with retraction of the tefticle in men, and numbnefs on the infide of the thigh in women. It is diftinguifhed from the lumbago or fciatica, as thefe latter are feldom attended with vomiting, and have pain on the outfide of the thigh, fometimes quite 4 down Class 1.1. 3.] OF IRRITATION. 49 down to the ankle or heel. See Herpes and Ne- phritis. Where the abforption of the thinner parts of the fecretion takes place too haftily in the kidneys, the hardened mucus, and confequent calculous concre- tions, fometimes totally flop up the tubuli uriniferi; and no urine is fecreted. Of this many die, who have drank much vinous fpirit, and fome of them recover by voiding a quantity of white mucus, like chalk and water; and others by voiding a great quantity of fand, or fmall calculi. This hardened mucus frequently becomes the nucleus of a ftone in the bladder. The falts of the urine, called micro- cofmic fait, are often miftaken for gravel, but are diftinguifhable both by their angles of cryftallization, their adhefion to the fides or bottom of the pot, and by their not being formed till the urine cools. Whereas the particles of gravel are generally with- out angles, and always drop to the bottom of the veSTel, immediately as the water is voided. Though the proximate caufe of the formation of the calculous concretions of the kidneys, and ofchalk- ftones in the gout, and of the infoluble concretions of coagulable lymph, which are found on membranes, which have been inflamed in peripneumony, or rheu- matifm, confifts in the too great action of the abforb- ent veflels of thofe parts; yet the remote caufe in thefe cafes is probably owing to the inflammation of the membranes ; which at that time are believed to fecrete a material more liable to coagulate or concrete,, E than $o DISEASES [Class I. i. 3. than they would otherwife produce by increafed ac- tion alone without the production of new veflels, which conftitutes inflammation. As defined in Clafs II. 1. 2. The fluids fecreted from the mucous membranes of animals are of various kinds and confiftencies. Hair, filk, fcales, horns, finger-nails, are owing to natural procelfes. Gall-ftones, ftones found in the inteftines of horfes, fcurf of the ikin in leprofy, ftones of the kidneys and bladder, the callus from the inflamed pe- riofteum, which unites broken bones, the calcareous cement, which repairs the injured fliells of fnails, the calcareous cruft on the eggs of birds, the annually re- newed Shells of crabs, are all inftances of productions from mucous membranes, afterwards indurated by ab- forption of their thinner parts. All thefe concretions contain phofphoric acid, mu- cus, and calcareous earth in different proportions; and are probably fo far analogous in refpect to their component parts as well as their mode of formation. Some calcareous earth has been difcovered after pu- trefaction in the cOagulable lymph of animals. For- dyce's Elements of Practice. A little calcareous earth was detected by Scheel or Bergman in the calculus of the bladder with much phofphoric acid, and a great quantity of phofphoric acid is fhewn to exift in oyfter- fhells by their becoming luminous on expofing them a while to the fun's light after calcination ; as in the experiments of Wilfon. Botanic Garden, P. 1. Canto \. 1, 182, note. The exchange of which phofphoric acid Class I. i. 3.] OF IRRITATION. 51 acid for carbonic acid, or fixed air, converts Shells into limeftone, producing mountains of marble, or calcare- ous Strata. Now as the hard lumps of calcareous matter, term- ed crabs' eyes, which are found in the Stomachs of thofe animals previous to the annual renewal of their Shells, are redilfolved, probably by their gaftric acid, and again depofited for that purpofe ; may it not be concluded, that the ftone of the bladder might be dif- folved by the gaftric juice of fifli of prey, as of crabs, or pikes ; or of voracious young birds, as young rooks or hawks, or even of calves ? Could not thefe experiments be tried by collecting the gaftric juice by putting bits of fponge down the throats of young crows, and retracting them by a String in the manner of Spallanzani ? or putting pieces of calculus down the throat of a living crow, or pike, and obferving if they become digefted? and laftly, could not gaftric juice, if it Should appear to be a folvent, be injected and born in the bladder without injury by means of catheters of elaftic refin, or caoutchouc ? M. M. Diluents. Cool drefs. Frequent change of pofture. Frequent horizontal reft in the day. Bathe the loins every morning with a fponge and cold water. Aerated alkaline water internally. Absti- nence from all fermented or fpirituous liquors. What- ever increafes perfpiration injures thefe patients, as it diflipates the aqueous particles, which ought to dilute the urine. When the constitution begins to produce gravel, it may 1 believe be certainly prevented by a E 2 total 5* BISEASE3 [Class I. i. 5, \q\$ abftin«H.ej| from fermented or fpirituous liquors; by 4rinking much aqueous fluids; as toaft and wa- ter, tea, milk and water, lemonade ; and laftly by t^n clothing, and fleeping on a, hardifh bed, that the patient may not lie too long on one fide. See Clafs IV. 2. 2. 2. There is reafon to believe, that the dguty ufe of opium contributes to produce gravel in the kidneys by increasing abforption, when they are in- flamed ; in th^ fame manner as is done by fermented or (pirituous liquor. See Clafs I. 3, 2. 11. "\Vhen the kidneys are. fo obstructed with gravel, that no urine pafles into the bladder ; which is known by the external appearance of the lower part of the abdomen, which, when the bladder is full, feems as if contracted by a cord between the navel and the bladder; and by the tenfion on the region of the bladder distinguishable by the touch ; or by the intro-. duction of the catheter; the following methods of cure are frequently fuccefsful. Venefection to fix or eight ounces, ten grains of calomel, and an infufion of fenna with falts and oil, every three hours, till ftools are procured. Then an emetic. After the patient has been thus evacuated, a blifter on the loins, fhould be ufed; and from ten to twenty electric Shocks fhould be pajfed through the kidneys, as large as can he ea- fily borne, once or twice a day. Along with this method the warm bath Should be ufed for an hour once or twice a day. After repeated evacuations a clyfter, confifting of two drams of turpentine diifolved by yolk of egg, and fixry drops of tiacture of opium, Should I Class I. i. 3.] OF IRRITATION. 53 mould be ufed at night, and repeated, with cathartic medicines interpofed, every night, or alternate nights. Aerated Solution of alkali fhould be taken internally, and balfam of copaiva, three or four times a day. Some of thefe patients recover after having made no water for nine or ten days. If a ftone flicks in the ureter with incefiant vomit- ing, ten grains of calomel muft be given in fmall pills as above ; and fome hours afterwards infufion of fenna and falts and oil, if it can be made to Slay on the fto- mach. And after the purge has operated four or five times, an opiate is to be given, if the pain con- tinues, confifting of two grains of opium. If this does not fucceed, ten or twenty electric Shocks through the kidneys Should be tried, and the purgative repeated, and afterwards the opiate. The patient fhould be fre- quently put into the warm bath for an hour at a time. Eighty or an hundred drops of laudanum given in a clyfter, with two drams of turpentine, is to be pre- ferred to the two grains given by the ftomach as above, when the pain and vomiting are very urgent. 10. Calculus vefica. Stone of the bladder. The nucleus, or kernel, of thefe concretions is always formed in the kidney, as above defcribed; and paf- fing down the ureter into the bladder, is there per- petually increafed by the mucus and falts fecreted from the arterial fyftem, or by the mucus of the blad- der, difpofed in concentric ftratn. The ftones found in the bowels of horfes are alfo formed On a nucleus, E 3 and 54 DISEASES [ClassI. 1.3. and confift of concentric fpheres; a^ appears in faw- ing them through the middle. But as thefe are form- ed by the indurated mucus of the inteftines alone without the urinary falts, it is probable a difference would be found on their analyfis. As the ftones of the bladder are of various degrees of hardnefs, and probably differ from each other in the proportions at leaft of their component parts ; when a patient, who labours under this afflicting dif- eafe, voids any fmall bits of gravel; thefe Should be kept in warm folutions of cauftic alkali, or of mild alkali well aerated ; and if they diflblve in thefe folu- tions, it would afford greater hopes, that that which remains in the bladder, might be affected by thefe medicines taken by the ftomach, or injected into the bladder. To prevent the increafe of a Stone in the bladder much diluent drink fhould be taken; as half a pint of water warmed to about eighty degrees, three or four times a day : which will not only prevent the growth of it, by preventing any microcofmic falts from being precipitated from the urine, and by keeping the mu- cus fufpended in it; but will alfo diminifh the ftone already formed, by foftening and wafliing away its furface. To this muft be added cool drefs, and cool bed-clothes, as directed above in the calculus renis. When the ftone is pufhed againft or into the neck of the bladder, great pain is produced; this may fometimes be relieved by the introduction of a bou- gie to pufh the ftone back into the fundus of the blad- der, Class I. 1.3.] OF IRRITATION. 55 der. Sometimes by change of pofture, or by an or U ate either taken into the ftomach, or by a clyfter. A dram of fal foda, or of fait of tartar, diflblved in a pint of water, and well faturated with carbonic acid (fixed air), by means of Dr. Nooth's glafs-apparatus, and drank every day, or twice a day, is the moft effi- cacious internal medicine yet difcovered, which can be eafily taken without any general injury to the con- stitution. An aerated alkaline water of this kind is fold under the name of factitious Seltzer wTater, by J. Schweppe, at N° 8, King's Street, Holborn, Lon- don ; which I am told is better prepared than can be eafily done in the ufual glafs-veffels, probably by em-. ploying a greater prefTure in wooden ones. Lythotomy is the laft recourfe. Will the gaftric juice of animals diifolve calculi ? Will fermenting ve- getable juices, as fweet-wort, or fugar and water in the act of fermentation with yeft, diifolve any kind of animal concretions ? n. Calculus arthriticus. Gout-ftones are formed on inflamed membranes, like thofe of the kidneys above defcribed, by the too hafty abforption of the thinner and Saline parts of the mucus. Similar con- cretions have been produced in the lungs, and even in the pericardium ; and it is probable, that the offi- fication, as it is called, of the minute arteries, which is faid to attend old age, and to precede fome mor- tifications of the extremities, may be a proccfs of this kind. 5« DISEASES [Class I. 1.3. As gout-ftones lie near the furface, it is probable, that ether, frequently applied in their early State, might render them fo liquid as to permit their re- abforption; which the Stimulus of the ether might at the fame time encourage. 12. Rheumatifmus chronicus* Chronic rheumatifm. After the acute rheumatifm fome infpiflated mucus, or material fimilar to chalk-ftones of the gout, which was fecreted on the inflamed membrane, is probably left, owing to the too hafty abforption of the thin- ner and faline part of it; and by lying on the faf- cia, which covers fome of the mufcles, pains them, when they move and rub againft it, like any extra- neous material. The pain of the Shoulder, which attends inflamma- tions of the upper membrane of the liver, and the pains of the arms, which attend afthma dolorificum, or dropfy of the pericardium, are distinguished from the chronic rheumatifm, as in the latter the pain only occurs on moving the affected mufcles. M. M. Warm bath, cold bath, bandage of em- plaftrum de minio put on tight, fo as to comprefs the part.- Cover the part with flannel. With oiled filk. Rub it with common oil frequently. With ether. A blifter. A warmer climate. Venefection. A grain of calomel and a grain of opium for tea fuc:effive nights.. The Peruvian bark. 13, Cicatrix vulnerum. The fear after wounds. jn the healing of ulcers the matter is firft thickened by Class I. i. 3.] OF IRRITATION. ^ by increafing the abforption in them; and then leflen- ed, till all the matter is abforbed, which is brought by the arteries, inftead of being depofited in the ulcer. M. M. This is promoted by bandage, by the for- bentia externally, as powder of bark, white lead; folution of fugar of lead. And by the forbentia in- ternally after evacuations. See Sect, XXXIII. 3. 2. In thofe ulcers, which are made by the contact of external fire, the violent action of the fibres, which occafions the pain, is liable to continue, after the ex- ternal heat is withdrawn. This fhould be relieved by external cold, as of fnow, fait and water recently mix- ed, ether, or Spirits of wine fuffered to evaporate on the part. The cicatrix of an ulcer generally proceeds from the edges of it; but in large ones frequently from the middle, or commences in feveral places at the fame time ; which probably contributes to the uneven- nefs of large fears. 14. Cornea obfufcatio* Opacity of the cornea. There are few people, who have paffed the middle of life, who have not at fome time fuffered fome flight fcratches or injuries of the cornea, which by not heal- ing with a perfectly fmooth furface, occafion fome re- fractions of light, which may be conveniently feen in the following manner: fill a tea-faucer with cream and tea, or with milk, and holding it to your lips, as if going to drink it, the imperfections of the cornea will appear like 13ne> or bio- dies en the furface of the fluid, 5$ DISEASFrS [Class I. 1.3. fluid, with a lefs white appearance than that furface. Thofe blemifhes of the eye are diftinguifhed from the mufce volitantes defcribed in Clafs I. 2. 5. 3. by their being invariably feen at any time, when you look for them. Ulcers may frequently be feen on the cornea after ophthalmy, like little pits or indentations beneath the furface of it: in this cafe no external application fliould be ufed, left the fear fliould be left uneven ; but the cure fliould be confined to the internal ufe of thirty grains of bark twice a day, and from five to ten drops of laudanum at night, with five grains of rhubarb, if neceflary. After ulcers of the cornea, which have been large, the inequalities and opacity of the cicatrix obfeures the fight; in this cafe could not a fmall piece of the cornea be cut out by a kind of trephine about the Size of a thick brittle, or a fmall crow-quill, and would it not heal with a tranfparent fear ? This experiment is worth trying, and might be done by a piece of hol- low fteel wire with a Sharp edge, through which might be introduced a pointed fteel fcrew ; the fcrew to be introduced through the opake cornea to hold it it up, and prefs it againft the cutting edge of the hol- low wire or cylinder ; if the fear Should heal without lofing its tranfparency, many blind people might be made to fee tolerably well by this flight and not pain- ful operation. An experiment I wifh Strongly to re- commend to fome ingenious furgeon or oculift. ORDO Class I. 1.4.] OF IRRITATION. 59 ORDO I. Increafed Irritation* GENUS IV. With increafed Aclions of other Cavities and Membranes* SPECIES. 1. ISliclitatio irritativa. Winking of the eyes is performed every minute without our attention, for the purpofe of cleaning and moiftening the eye-ball; as further fpoken of in Clafs II. 1. 1. 8. When the cornea becomes too dry, it becomes at the fame time lefs tranfparent; which is owing to the pores of it be- ing then too large, fo that the particles of light are refracted by the edges of each pore, inftead of paifing through it; in the fame manner as light is refracted by pafling near the edge of a knife. When thefe pores are filled with water, the cornea becomes again tranfparent. This want of transparency of the cor- nea is vifible fometimes in dying people, owing to their inirritability, and confequent neglect of nictitation. The increafe of tranfparency by filling the porei with fluid is feen by foaking white paper in oil; which from an opake body becomes very tranfpa- rent, and accounts for a curious atmofpheric phe- nomenon;-when there exifts a dry-mift in a morning fo as to render diftant objects Ufs diftinct, it is a fign of a dry day; when diftant objects are feen very 6o DISEASES [Class I. 1.4. very diftinct, it is a fign of rain. Sec Botan. Garden/ Part I. add. note xxv. The particles of air are pro- bably larger than thofe of water, as water will pafs through leather and paper, which will confine air ; hence when the atmofphere is much deprived of moi- fture, the^pores of the dry air are fo large, that the rays of light are refracted by their edges inftead of paSEng through them. But when as much moifture is added as can be perfectly diflolved, the air becomes tranfparent; and opake again, when a part of this moifture collects into fmall fpherules previous to its precipitation. This alfo accounts for the want of transparency of the air, which is feen in tremulous mo- tions over corn-fields on hot fummer-days, or over brick-kilns, after the flame is extinguifhed, while the furnace ftill remains hot. 2. Deglufitio irritativa. The deglutition of our fa- liva is performed frequently without! our attention, and is then an irritative action in confequence of the ftimulus of it in the mouth. Or perhaps fometimes; for the purpofe of diffufing a part of it over the dry membranes of the fauces and pharynx ; in the fame manner as tears are diffufed over the cornea of the eye by the act of nictitation to clean or moiften it. 3. Refpiratio et Tuffs irritativa. In the acts of re- fpiration and of coughing there is an increafed motion* of the air-cells of the lungs owing to fome ftimulating caufe, as defcribed above in Clafs I. 1. 2. 8. and I. 1. 3. 4. Class I. r. 4.] OF IRRITATION. *i 1. 3. 4. and which are frequently performed without our attention or confcioufnefs, and are then irritative actions ; and thus differ from thofe defcribed in Clafs II. 1. 1. 2. and 5. To thefe increafed actions of the air-cells are fuperadded thofe of the intercoftal mufcles and diaphragm by irritative aflbciation. When any unnatural ftimulus acts fo violently on the organs of refpiration as to induce pain, the fenforial power of fenfation becomes added to that of irritation, and in- flammation of the membranes of them is a general con- fequence. 4. Exclufio bills. The exclufion of the bile from the gall-bladder, and its derivation into the duodenum, is an irritative action in confequence of the ftimulus of the aliment on the extremity of the biliary duct, which terminates in the inteftine. The increafed fecretion of tears is occafioned in a fimilar manner by any fti- mulating material in the eyes; which affects the ex- cretory ducts of the lacrymal glands. A pain of the external membrane of the eye fometimes attends any unufual ftimulus of it, then the fenforial power of fen- fation becomes added to that of irritation, and a fo- perficial inflammation is induced. 5. Dentitio. Toothing. The pain of toothing often begins much earlier than is fufpected ; and is liable to produce convulfions; which are fometimes relieved, when the gum fvvells, and becomes inflamed y at other times a diarrhcea Supervenes, which is gene- rally 6z DISEASES [Class I. i. 4. rally efteemed a favourable circumftance, and feems to prevent the convulfions by fupplying another means of relieving the pain of dentition by irritative exertion ; and a confequent temporary exhauftion of fenforial power. See Clafs I. 1.2. 5. Sect. XXXV. 2. 1. The convulfions from toothing generally commence long before the appearance of the teeth ; but as the two middle incifors of the lower jaw generally appear firft, and then thofe of the upper, it is advifeable to lance the gums over thefe longitudinally in refpect to the jaw-bones, and quite down to the periofteum, and through it. As the convulfions attending the commencement of toothing are not only dangerous to life in their greateft degree, but are liable to induce Stupor or infenfibility by their continuance even in a lefs degree, the moft efficacious means Should be ufed to cure them. M. M. Lance the gum of the expected teeth quite through the periofteum longitudinally. Venefection by the lancet or by two or three leeches One grain of calomel as a purge. Tincture of jalap, five or fix drops in water every three hours till it purges, to be repeated daily. After evacuations a fmall blifter on the back or behind the ears. And laftiy, two or three drops of laudanum according to the age of the s.'.l;L&. Warm bath. See Clafs III. 1. 1. 5. and 6. 6. Priapifmus chronicus. I have feen two cafes, where an erection of the penis, as hard ,as horn, con- \inued two or three weeks without any venereal de- fires,, Class I. 1.4.] OF IRRITATION. 63 fires, but not without fome pain; the eafieft attitude of the patients was lying upon their backs with their knees up. At length the corpus cavernofum urethre became foft, and in another day or two the whole fub- fided. In one of them a bougie was introduced, hoping to remove fome bit of gravel from the caput gallinaginis, camphor, warm bathing, opium, lime- wrater, cold afperfion, bleeding in the veins of the pe- nis, were tried in vain. One of them had been a free drinker, had much gutta rofacea on his face, and died fuddenly a few months after his recovery from this complaint. Was it a paralyfis of the terminations of the veins, which abfprb the blood from the tumid pe- nis ? or from the ftimulus of indurated femen in the feminal veflels ? In the latter cafe fome venereal de- fires fhould have attended. Clafs III. 1. 2. 16. The priapifmus, which occurs to vigorous people in the morning before they awake, has been called the fignum falutis, or banner of health, and is occafioned by the increafe of our irritability or fenfibility during fleep, as explained in Sect. XVIII. 15. 7. Difientio mamularum. The diftention of the nip- ples of ladtefcent women is at firft owing to the fti- mulus of the milk. See Sect. XIV. 8. and Sect. XVI. 5. See Clafs II. 1. 7. 10. 8. Defcenfus uteri. This is a very frequent com- plaint after bad labours, the fundus uteri becomes hvened and defcends like the prolapfus ani. M, M. Ail 64 DISEASES [Class I. i. 4. M. M. All the ufual peflaries are very inconve- nient and ineffectual. A piece of foft fponge about two inches diameter introduced into the vagina gives great eafe to thefe patients, and fupports the uterus ; it fhould have a String put through it to retract it by. There are alfo peflfaries now made of elaftic gum, which are faid to be eafily worn, and to be conve- nient, from their having a perforation in their centre. 9. Prolapfus ani* The lower part of the rectum becomes inverted, and defcends after every ftool chiefly in children; and thus Stimulates the fphincter ani like any other extraneous body. M. M. It Should be dufted over with very fine powder of gum fandarach, and then replaced. Astrin- gent fomentations; as an infufion of oak-bark, or a flight folution of alum. Horizontal reft frequently in the day. 10. Lumbricus. Round worm. The round worm is fufpedted in children when the belly is tumid, and the countenance bloated and pale, with Swelling of the upper lip. The generation of thefe worms is promoted by the too dilute State of the bile, as is evident in the fleuke-worm found in the biliary ducts and fubftance of the liver in fheep ; and in water- rats, in the livers of which laft animals they were lately detected in large numbers by Dr. Capelle* Tranfactions of the College at Philadelphia, v. i. z Now Class I. i. 4.] OF IRRITATION. 6$ Now as the dilute Slate of the bile depends on the deficiency of the abforption of its thinner parts, it appears, that the tumid belly, and bloated counte- nance, and Swelled upper lip, are a concomitant cir- cumftance attending the general inactivity of the ab- forbent fyftem ; which is therefore to be efteemed the remote caufe of the generation of worms. The fimplicity of the Structure of worms probably enables them to exift in more various temperatures of heat; and their being endued with life prevents them from being deftroyed by digeftion in the ftomach, pro- bably in the fame manner as the powers of life pre- vent the fermentation and putrefaction of the ftomach itfelf. Hence I conclude, that worms are originally taken into our alimentary canal from without; as I believe fimilar worms of all kinds are to be found out of the body. M. M. The* round worm is deftroyed by a cathar- tic with four or fix grains of calomel; and afterwards by giving fix or eight grains of filings of iron twice a day for a fortnight. See Hepatis tumor, Clafs I. 2. 3. 9. As worms are liable to come away in fevers, whether of the hectic or putrid kind, could they be removed by purulent matter, or rotten egg, or putrid flefli, fince in thofe fevers from the enfeebled action of the inteftines the feces become highly putrid ? 11. Tania. Tape-worm confifts of a chain of ani- mals extending from the ftomach to the anus. See Sect. XXXIX. 2. 3. It frequently exifts in cats, rats, and gecfe, and probably in many other animals. F The 66 DISEASES [Class I. i. 4. The worms of this genus poffefs a wonderful power of retaining life. Two of them, which were voided by a pointer dog in confequence of violent purgatives, each of whicji were feveral feet in length, had boiling water poured on them in a bafon ; which feemed not much to inconvenience them. When the w ater was cool, they were taken out and put into gin or whilkey of the Strongest kind, in which their life and activity continued unimpaired; and they were at length killed by adding to the fpirit a quantity of corrofive fubli- mate. Medic. Comment, for 1791, p. 370. The tape-worm is cured by an amalgama of tin and quickfilver, fuch as is ufed on the back of looking- glaffes; an ounce fhould be taken every two hours, till a pound is taken; and then a bri/k cathartic of Glauber's fait two ounces, and common falts one ounce, diffolved in two wine pints of water, half a pint to be taken every hour till it purges. The worm extends from the ftomach to the anus, and the amal- gama tears it from the inteftine by mechanical pref- fure, acting upon it the whole way. Electric fhocks through the duodenum greatly affifts the operation. Large dofes of tin in powder. Iron filings in large 4ofes. The powder of fern-root feems to be of no ufe, as recommended by M. Noufflier. 12. Afcarides. Thread-worms. Thefe worms are faid to be more frequent in fome parts of this king- dom than in others, as near the fens of Lincolnfhire. Do they efeape from the body and become flies, like the bott-worm in horfes ? Do they crawl from one child Class I. i. 4.] OF IRRITATION. €7 child to another in the fame bed ? Are they acquired from flies or worms, which are feen in putrid necef- fary houfes, as thefe worms as well as the tape-worms^ are probably acquired from without ? this may ac- count for their re-appearance a few weeks or months after they have .been deftroyed; or can this happen from the eggs or parts of them remaining ? Afcarides appear to be of two kinds, the common fmall ones like a thread; which has a very Sharp head, as appears in the microfcope; and which is fo tender, that the cold air foon renders it motionlefs; and a larger kind above an inch long, and nearly as thick as . a very fmall crow-quill, and which is very hard in re- fpect to its texture, and very tenacious of life. One of thefe laft was brought to me, and was immediately immerfed in a ftrong folution of fugar of lead, and lived in it a very long time without apparent inconvenience. M. M. Afcarides are faid to be weakened by twenty grains of cinnabar and five of rhubarb taken every night, but not to be cured by this procefs. As thefe worms are found only in the rectum, variety of clyfters have been recommended. I was informed of a cafe, where folutions of mercurial ointment were ufed as a clyfter every night for a month without fuccefs. Clyfters of Harrowgate water are recom- mended, either of the natural, or of the factitious, as defcribed below, which might have a greater pro- portion of liver of fulphur in it. As the cold air fo©n deftroys them, after they are voided, could cly- fters of iced water be ufed with advantage? or of F 2 fpirit. 6S DISEASES [Class I. i. 4. fpirit of wine and water ? or of ether and water ? M}ight not a piece of candle, about an inch long, or two fuch pieces, fmeared with mercurial ointment, and introduced into the anus at night, or twice a day, be effectual by compreSfing their nidus, as well as by the poifon of the mercury. The clyfters fhould be large in quantity, that they may pafs high in the rectum, as two drams of to- bacco boiled a minute in a pint of water. Or per- haps what might be ftill more efficacious and lefs inconvenient, the fmoke of tobacco injected by a pro- per apparatus every night, or alternate nights, for fix or eight weeks. This was long fince recommend- ed, I think by Mr. Turner of Liverpool; and the reafon it has not fucceeded, I believe to have been owing to the imperfections of the joints of the com- mon apparatus for injecting the fmoke of tobacco, fo that it did not pafs into the inteftine, though it was fuppofed to do fo, as I once obferved. The fmoke fliould be received from the apparatus into a large bladder; and it may then be certainly injected like the common clyfter with, fufficient force ; other- wife oiled leathers fhould be nicely put round the joints of the machine ; and a wet cloth round the injecting pipe to prevent the return of the fmoke by the fides of it. Clyfters of carbonated hydrogen gas, or of other factitious airs, might be tried. Harrowgate water taken into the ftomach, fo as to induce fix or feven ftools every morning, for four or fix weeks, is perhaps the moft efficacious method in common Class I. i. 4.J OF IRRITATION. €9 common ufe. A factitious Harrowgate water may be made probably of greater efficacy than the natural, by diflblving one ounce of marine fait, (called bay fait) and half an ounce of magnefia Glauber's fait, (called Epfom fait, or bitter purging fait) in twenty-eight ounces of water. A quarter Or half a pint of this is to be taken every hour, or two hours in the morning, till it operates, with a tea-fpoonful of a folution of liver of fulphur, which is to be made by putting an ounce of hepar fulphuris into half a pint of water. See Clafs IV. 1. 2. 9. 13. Dracunculus. A thin worm brought from the coaft of Guinea. It is found in the interftices of the mufcles, and is many yards long; it makes a fmall ul- cer ; which is cured by extracting an inch of the worm a day, and wrapping the extracted part flowly round a bit of tobacco pipe till next day, fo as not to break it. I have twice feen long worms, like a thick horfe- hair, in water in July in this country, which appeared hard and jointed. 14. Morpiones. Crab-lice. The excrement of this animal ftains the linen, and appears like diluted blood. M. M. Spirit of wine. Mercurial ointment, Shaving the part. Oil deftroys other infects, if they be quite covered with it, as the ticks on dogs5 and would pro- bably therefore deftroy thefe. Its manner of opera- tion is by flopping up or filling their fpiracula, or F 3 breathing 7« DISEASES [Class^. 1.5. breathmg pores; a few drops of oil poured on a wafp, fo as to cover it, deftroys it in a few fecon DISEASES [Class 1 2. i. In other cafes the lochia continues too long,' or in too great quantity, owing to the deficiency of venous abforption. M. M. Ah encr.a. An opiate. A blifter. Slight chaiybeates. Peruvian bark. Clothes dipped in cold vinegar,. and applied externally. Bandages on the limbs to keep more blood in them for a time have been recommended. 14. Abortio fpontanea. Some delicate ladies are perpetually liable to fpontaneous abortion, before the third, or after the feventh, month of geftation. From fome of thefe patients I have learnt, that they have awakened with a flight degree of difficult refpira- tion, fo as to induce them to rife haftily up in bed; and have hence fufpected, that this was a tendency to a kind of aftlima, owing to a deficient abforption of blood in the extremities of the pulmonary or bronchial veins ; and have concluded from thence, that there was generally a deficiency of venous ab- forption ; and that this was the occafion of their fre- quent abortion. Which is further countenanced, where a great fanguinary difcharge precedes or fol- lows the exclufion of the fetus. .. Ivl, M. Opium, bark, chaiybeates in fmall quan- tity. Change to a warmer climate. I have directed with fuccefs in four cafes half a grain of opium twice a day for a fortnight, and then a whole grain twice a day during the whole geftation. One of thefe pa- tients took bellies twenty grains of Peruvian bark for Class 1.2. 1.] OF IRRITATION. gi for feveral weeks. By thefe means being exactly and regularly perfifted in, a new habit became efta- bliftted, and the ufual mifcarriages were prevented. Mifcarriages more frequently happen from eruptive fevers, and from rheumatic ones, than from other inflammatory difeafes. I faw a moft violent pleurify and hepatitis cured by.repeated venefection about a week or ten days before parturition ; yet another lady whom I attended, mifcarried at the end of the chicken pox, with which her children were at the fame time affected. Mifcarriages towards the termi- nation of the fmall pox are very frequent, yet there have been a few inftances of children, who have been born with the eruption on them. The blood in the fmall pox will not inoculate that difeafe, if taken be- fore the commencement of the fecondary fever ; as Shewn in Sect. XXXIII. 2. 10.^ becaufe the conta- gious matter is not yet formed, but after it has been oxygenated through the cuticle in the puftules, it be- comes contagious; and if it be then abforbed, as in the fecondary fever, the blood of the mother may become contagious, and infect the child. The fame mode of reafoning is applicable to the chicken pox. See Clafs IV. 3. 1. 7. 15. Scorbutus. Sea-fcurvy is caufed by fait diet, the perpetual ftimulus of which debilitates the venous and abforbent fyftems. Hence the blood is imper- fectly taken up by the veins from the capillaries, whence brown and black fpots appear upon the ikin withput ** DISEASES [Class I. 2. f. without fever. The limbs become livid and edema- tous, and laftly ulcers are produced from deficient abforption. See Sect. XXXIII. 3. 2. and Clafs II. i, 4. 13. For an account of the fcurvy of the lungs, fee Sea. XXVII. 2. M. M. Frefh animal and vegetable food. Infufion ©f malt. New beer. Sugar. Wine. Steel. Bark. Sorbentia. Opium ? 16. Vibices* Extravafations of blood become black from their being fecluded from the air. The extra- vafation of blood in bruifes, or in fome fevers, or after death in fome patients, efpecially in the parti which were expofed to preffure, is owing to the fine terminations of the veins having been mechanically eompreffed fo as to prevent their abforbing the blood from the capillaries, or to their inactivity from dif- eafe. The blood when extravafated undergoes a che- mical change before it is fufficiently fluid to be taken «p by the lymphatic abforbents, and in that procefa ehangcs its colour to green and then yellow. < 17. Petechia. Purple fpots. Thefe attend fevers with great venous inirritability, and are probably formM by the inability of a Angle termination of a vein, wncnce the corresponding capillary becomes rup- tured, and effufes the blood into the cellular mem- brane round the inert termination of the vein. This h generally efteemed a fign of the putrid Slate of the )>lood, or that State contrary to the inflammatory one. As Class I. 2. 2.3 OF IRRITATION. 9j As it attends fome inflammatory difeafes which are attended with great inirritability, as in the confluent fmall pox. But it alfo attends the fcurvy, where no fever exifts, and it therefore fimply announces the inactivity of the terminations of fome veins; and is thence indeed a bad fymptom in fevers, as a mark of approaching inactivity of the whole fanguiferous fyftem, or death. The blue colour of fome children's arms or face* in very cold weather is owing in like manner to the torpor of the abforbent terminations of the veins, whence the blood is accumulated in tfeem, and fometimes burfts them. ORDO II. Decreafed Irritation* GENUS II. Decreafed Aclion of the Secerning Syfiem, These are always attended with decreafe of par- tial, or of general heat; for as the heat of anima! bodies is the confequence of their various fecretions, and is perpetually pafling away into the ambient air, or other bodies in contact with them; when thefe fecretions become diminiflied, or ceafe, the heat of the part or of the whole is foon diminished, or ceafes along with them. SPECIES. *+ DISEASES [Class I. a. ». SPECIES. i. Frigus febrile. Febrile coldnefs. There is rea- fon to believe, that the beginning of many fever-fits originates in the quiefcence of fome part of the ab- forbent fyftem, efpecially where they have been owing to external cold ; but that, where the coldnefs of the body is not owing to a diminution of external heat, it arifes from the inaction of fome part of the fecerning fyftem. Hence fome parts of the body are hot whilft other parts are cold ; which I fuppofe gave occafion to error in Martyn's Experiments; where he fays, that the body is as hot in the cold paroxyfms of fevers as at other times. After the fenforial power has been much diminiflied by great preceding activity of the fyftem, as by long continued external heat, or violent exercife, a fudden expofure to much cold produces a torpor both greater in degree and over a greater portion of the fyftem, by fubtracting their accuftomed ftimulus from parts already much deprived of their irritability./ Dr. Franklin in a letter to M. Duberge, the French tranf- lator of his works, mentions an inftance of four young men, who bathed in a cold fpring after a day's har- veft work ; of whom two died on the fpot, a third on the next morning, and the other furvived with diffi- culty. Hence it would appear, that thofe, who have to travel in intenfely cold weather, will fooner perifh, who have previoufly heated themfelves much with drams, than thofe who have only the ftimulus of na- tural Cass I. 2. 2.] OF IRRITATION. r? tural food ; of which I have heard one well attefted inftance. See Article VII. 2. 3. Clafs III. 2. 1. 17. Frfcus chronicum. Permanent coldnefs. Coldnefi of the extremities, without fever, with dry pale /kin, is a fymptom of general debility, owing to the de- creafed action of the arterial fyftem, and of the ca- pillary veffels; whence the perfpirable matter is fe- creted in lefs quantity, and in confequence the /kin is lefs warm. This coldnefs is obfervable at the ex- tremities of the limbs, ears, and nofe, more than in any other parts : as a larger furface is here expofed to the contact of the air, or clothes, and thence the heat is more haftily carried away. The pain, which accompanies the coldnefs of the ikin, is owing to the deficient exertion of the fub- cutaneous veflels, and probably to the accumulation of fenforial power in the extremities of their nerves. See Sect. XII. 5. 3. XIV. oh XXXII. 3. and Clafs I. 2, 4. 1. M. M. A blifter. Incitantia, nutrientia, forbentia. Exercife. Clothes. Fire. Joy. Anger. 2. Pallor fugitivus. The fugitive palenefs, which accompanies the coldnefs of the extremities, is owing to a lefs quantity of blood pafling through the capil- laries of the /kin in a given time ; where the abforb- ent power of the veins is at the fame time much dimi- niflied, a part of the blood lingers at their junction with the capillary arteries, and a blutfh tinge is mixed with 0 DISEASES [Class I. 2.2. with the palenefs; as is feen in the loofe ikin under the eye-lids, and is always a mark of temporary debi- lity. See Clafs II. 1. 4. 4. Where the palenefs of the ikin is owing to the deficiency of red globules in the blood, it is joined with a yellowifh tinge ; which is the colour of the ferum, with which the blood then abounds, as in chlorofis, and in torpor or paralyfis of the liver, and is often mistaken for a fuperabundance of bile. A permanent palenefs of the /kin is owing to the coalefcence of the minute arteries, as in old age. See Clafs I. 2. 2. 9. There is another fource of palenefs from the increafed abforption of the terminations of the veins, as when vinegar is applied to the lips. See Sect. XXVII. 1. and another from the retrograde mo- tions of the capillaries and fine extremities of the arte- ries. See Clafs II. 3. 1. 1. M. M. A blifter, nutrientia, incitantia, exercife, oxygene gas. 3. Pus parcius. Diminifhed pus. Drynefs of ul- cers. In the cold fits of fever all the fecretions are diminiflied, whether natural or artificial, as their quan- tity depends on the actions of the glands or capilla- ries, which then Share in the univerfal inaction of the fyftem. Hence the drynefs of iffues and blifters in great debility, and before the approach of death, is owing to deficient fecretion, and not to increafed ab- forption. > M. M. Opium, Class I* 2. 2.] OF IRRITATION. 57 M. M. Opium, wine in very fmall quantities, Peru* vian bark. 4. Mucus parcior. Diminiflied mucus. Drynefs of the mouth and noftrils. This alfo occurs in the cold fits of intermittents. In thefe cafes I have alfo found the tongue cold to the touch of the finger, and the breath to the back of one's hand, when oppofed to it, which are very inaufpicious fymptoms, and gene- rally fatal. In fevers with inirritability it is generally efteemed a good fymptom, when the noftrils and tongue become moift after having been previoufly dry ; as it fhews an increafed action of the mucous glands of thofe membranes, which were before torpid. And the contrary to this is the facies Hippocratica, or counte- nance fo well defcribed by Hippocrates, which is pale, cold, and fhrunk ; all which are owing to the inacti- vity of the fecerning veffels, the palenefs from there being lefs red blood pafling through the capillaries, the coldnefs of the ikin from there being lefs fecretion of perfpirable matter, and the fhrunk appearance from there being lefs mucus fecreted into the cells of the cellular membrane. See Clafs IV. 2. 4. 11. M. M. Blifters. Incitantia. 5. Urina parcior pallida. Paucity of pale urine, as in the cold fits of intermittents; it appears in fome nervous fevers throughout the whole difeafe, and feems to proceed from a palfy of the kidneys; which probably was the caufe of the fever, as the fever H fometimes \ 9& DISEASED [Class I. 2. r. fometimes ceafes, when that fymptom is removed : hence the ftraw-coloured urine in this fever is fo far falutary, as it fhews the unimpaired action of the kidneys. Mi-M,- Balfams, effential oil, afparagus, rhubarb, % blifter.. Cantharides internally. 6. Torpor hepaticus. Paueity of bile from a partial inaction of the liver ; hence the bombycinous colour of the /kin, grey ftools, urine not yellow, indigestion^. debility, followed by tympany, dropfy, and death. This paralyfis or inirritability of the liver often de- stroys thofe who have been long habituated to much fermented liquor, and have fuddenly omitted the ufe of it. It alfo deftroys plumbers, and houfe-pailiters, and in them feems a fubftitute for the colica fatusnina. See Seft. XXX. M. M. Aloe and calomel, then the bark, and cha- iybeates. Mercurial ointment rubbed on the region of the liver. Rhubarb, three or four grains, with opium half a grain to- a grain twice a day. Equita- tion,, warm bath for half an hour every day. 7. Torpor Pancreatis* Torpor of the pancreas* I faw what I conjectured to be a tumour of the pan- creas with indigeftion, and which terminated in the death of the patient. He had been for many years a great confumer of tobacco, infomuch that he chewed that noxious drug all the morning, and fmoaked it all the afternoon. As the fecretion from the pancreas re- fembles. Class I. 2. 2.] OF IRRITATION. ^ fembles faliva in its general appearance, and probably in its office of affifting digeftion, by preventing the fermentation of the aliment ; as would appear by the experiments of Pringle and Macbride ; there is reafon to fufpect, that a fympathy may exift between the fa- livary and pancreatic glands ; and that the perpetual ftimulus of the former by tobacco might in procefs of time injure the latter. See Tobacco, Article III. 2. 2. 8. Torpor renis. Inirritability or paralyfis of the kidneys is probably frequently mistaken for gravel in them. Several, who have lived rather intemperately in refpect to.fermented or Spirituous liquors, become fuddenly feized about the age of fixty, or later, with a total Stoppage of urine ; though they have previoufly had no fymptoms of gravel. In thefe cafes there is no water in the bladder ; as is known by the intro- duction of the catheter, of which thofe made of elaftic gum are faid to be preferable to metallic ones ; or it may generally be known by the Shape of the abdo^ men, either by the eye or hand. Bougies and cathe- ters of elaftic gum are fold at N° $y', Red Lion-ftreer, Holborn, London. M. M. Electric fhocks, warm bath. Emetics. Sec calculus renis, Clafs I. 1. 3. 9. When no gravel has been previoufly obferved, and the patient has been, a wine-drinker rather than an ale-drinker, the cafe is general!/ owing to inirritability of the tubuli urmiferi, and is frequently fatal. See Clafs I. 2. 4. 30. II 2 Q. Panels roo DISEASES [Class I. 2. r. 9. Puncla mucofa vultus Mucous fpots on the face. Thefe are owing to the inactivity of the excretory ducts of the mucous glands ; the thinner part of this fecretion exhales, and the remainder becomes infpif- fated, and lodges in the duct; the extremity of which becomes black by expofure to the air. M. M. They may be preffed out by the finger- nails. Warm water. Ether frequently applied. Blif- ter on the part I 10. Macula cutis fulva. Morphew or freckles* Tawny blotches on the ikin of the face and arms of elderly people, and frequently on their legs after flight eryfipelas. The freckles on the face of younger peo- ple, who have red hair, feem to be a Similar pro- duction, and feem all to be caufed by the coalefcence of the minute arteries or capillaries of the part. In a fear after a wound the integument is only opake; but in thefe blotches, which are called morphew and freckles, the fmall veffels feem to have become in- active with fome of the ferum of the blood Stagnating in them, from whence their colour. See Clafs III. 1. 2. 12. M, M. Warm bathing. A blifter on the part I 11. Canities. Grey hair. In the injection of the veffels of animals for the purpofes of anatomical pre- parations, the colour of the injected fluid will not pafs into many very minute veffels; which neverthe- *cfs uncoloured water, or fpirits, or quickfilver will permeate^ Class I. 2.-2.3 OF IRRITATION. lor -permeate. The fame occurs in the filtration of fome coloured fluids through paper, or very fine fand, where the colouring matter is not perfectly diffolved, but only diffufed through the liquid. This has led fome to imagine, that the caufe of the whitenefs of the hair in elderly people may arife from the dimi- nution, or greater tenuity, of the glandular veffelsi, which fecrete the mucus, which hardens into hair ; and that the fame difference of the tenuity of the fecerning veflels may poffibly make the difference of colour of the filk from different filk-worms, which is of all fhades from yellow to white. But as the fecreted fluids are not the confequence of mechanical filtration, but of animal feledtion ; we muft look out for another caufe, which muft be found in the decreafing activity of the glands, as we advance in life ; and which affects many of our other fecre- tions as well as that of the mucus, which forms the hair. Hence grey hairs are produced on the faces of horfes by whatever injures the glands at their roots, as by corrofive blifters; and frequently on the human Subject by external injuries on the head ; and fome- times by fevers. *And as the grey colour of hair con- fifts in its want of tranfparency, like water converted into fnow ; there is reafon to fuppofe, that a defect of fecreted moifture fimply may be the caufe of this kind of opacity, as explained in Cataracta, Clafs I. 2. 2. 13, M. M. Whatever prevents the inirritability and in- fcnfibility of the fyftem, that is, whatever prevents the approach of old age, will fo far counteract the pro- H 3 duction 102 DISEASES [Class I. 2. a. duction of grey hairs, which is a fymptom of it. For this purpofe in people, who are not corpulent, and perhaps in thofe who are fo, the warm bath twice or thrice a week is particularly ferviceable. See Sect. XXXIX. 5. 1. on the colours of animals, and Clafs I. 1. 2. 15. 12. Callus. The callous /kin on the hands and feet of laborious people is owing to the extreme vef- fels coaicfcing from the perpetual preffure they are expofed to. As we- advance in life, the finer arteries lofe their power of action, and their fides grow together ; hence the palenefs of the /kins of elderly people, and the Jofs of that bloom, which is owing to the numerous fine arteries, and the tranfparency of the fihin, that cnclofes them. M. M. Warm bath. Paring the thick ikin with a knife. Smoothing it with a pumice ftone. Cover the part with oiled filk to prevent the evaporation of the perfpirable matter, and thus to keep it moift. 13. Cataracla is an opacity of the cryftalline lens of the eye. It is a difeafe of light-coloured eyes, as the gutta ferena is of dark ones. On cutting off with fciffars the cornea of a calf's eye, and holding it in the palm of one's hand, fo as to gain a proper light, the artery, which fupplies nutriment to the cryftalline humour, is eafily and beautifully feen; as it rifes from the Class I. 2. 2.J OF IRRITATION. ro3 the centre of the optic nerve through the vitreous humour to the cryftalline. It is this point, where the artery enters the eye through the cineritious part of the optic nerve (which is in part near the middle of the nerve,) which is without fenfibility to light; as is Shewn by fixing three papers, each of them about half an inch in diameter, againft a wall about a foot diftant from each other, about the height of the eye ; and then looking at the middle one, with one eye, and re- treating till you tofe fight of one of the external pa- pers. Now as the animal grows older, the artery be- comes lefs vifible, and perhaps carries only a tranfpa- rent fluid, and at length in fome fubjects I fuppofe ceafes to be pervious ; then it follows, that the cry- ftalline lens, lofing fome fluid, and gaming none, be- comes dry, and in confequence opake; for the fame reafon, that wet or oiled paper is more tranfparent than when it is dry, as explained in Clafs I. 1.4. 1. The want of moifture in the cornea of old people, when the exhalation becomes greater than the fupply, is the caufe of its -want of tranfparency ; and which like the cryftalline gains rather a milky opacity. The fame analogy may be ufed to explain the whitenefs of the hair of old people, which lofes its pellucidity along with its moifture. See Clafs I. 2. 2. 11. M. M. Small electric Shocks through the eye. A quarter of a grain of corrofive fublimate of mercury diflblved in brandy, or taken in a pill, twice a day for fix weeks. Couching by depreifion, or by extraction. jThe former of thefe operations is much to be prefer- H 4 re>J 104 DISEASES [Class t. 2. 2. red to the latter, though the latter is at this time fo fafhionable, that a furgeon is almoft compelled to ufe it, left he fhould not be thought an expert operator, For deprefling the cataract is attended with no pain, no danger, no confinement, and may be as readily re- peated, if the cryftalline fhould rife again to the centre of the eye. The extraction of the cataract is attendee! with considerable pain, with long confinement, gene- rally with fever, always with inflammation, and fre- quently with irreparable injury to the iris, and confe- quent danger to the whole eye, Yet has this opera- tion of extraction been trumpeted into univerfal fa- shion for no other reafon but becaufe it is difficult to perform, and therefore keeps the bufinefs in the hands of a few empirics, who receive larger rewards, re- gardlefs of the hazard, which is encountered by the * flattered patient, A friend of mine returned yefterday from London after an abfence of many weeks; he had a cataract in a proper State for the operation, and in fpite of my earneft exhortation to the contrary, was prevailed up- on to have it extracted rather than depreffed. He was confined to his bed three weeks after the opera- tion, and is now returned with the iris adhering on one fide fo as to make an oblong aperture ; and which is nearly, if not totally, without contraction, and thus greatly impedes the little vifion, which he poffeffes. Whereas I faw fome patients couched by depre/fion many years ago by a then celebrated empiric, Che- valier Taylor, who were not confined above a day or Class 1.2. 2.] OF IRRITATION. 105 two, that the eye might gradually be accuftomed to light, and who faw as well as by extraction, perhaps better, without either pain, or inflammation, or any hazard of lofing the eye. As the inflammation of the iris is probably owing to forcing the cryftalline through the aperture of it in the operation of extracting it, could it not be done more fafely by making the opening behind the iris and ciliary procefs into the vitreous humour ? but the ope- ration would ftill be more painful, more dangerous, and not more ufeful than that by depreifing it. 14. Innutritio off urn. Innutrition of the bones. Not only the blood effufed in vibices and petechie, or from bruifes, as well as the blood and new veffels in in- flamed parts, are reabforbed by the increafed action of the lymphatics; but the harder materials, which conftitute the fangs of the firft fet of teeth, and the ends of exfoliating bones, and fometimes the matter of chalk-ftones in the gout, the coagulable lymph, which is depofited on the lungs, or on the mufcles after inflammation of thofe parts, and which frequent- ly produces difficulty of breathing, and the pains of chronic rheumatifm, and laftly the earthy part of the living bones are diffolved and abforbed by the increafed actions of this fyftem of veffels. See Sect. XXXIIL The earthy part of bones in this difeafe of the innu- trition of them fee»is to Suffer a folution, and reab- fo/ption ; while the fecerning veffels do not fupply a fufficient • rot) DISEASES [Class T. 2. 2. fcifiicient quantity of calcareous earth and phofphoric acid, which constitute the fubftance of bones. As calcareous earth abounds every where, is the want of phofphorie acid the remote caufe ? One caufe of this malady is given in the Pliilofophic Tranfactions, where the patient had been accuftomed to drink large quan- tities of vinegar. Two cafes are defcribed by Mr. Gouch. In one cafe, which I faw, a confiderabic quantity of calcareous earth, and afterwards of bone- afhes, and of decoction of madder, and alfo of fubli- mate of mercury, were given without effect. All the bones became foft, many of them brok^, and the pa- tient feemed to die from the want of beinf able to O diftend her cheft owing to the foftnefs of the ribs. M. M. Salt of urine, called fal microcofmicum, phofphorated foda. Calcined hartfhorn. Bone-aflies. Hard or petrifying water, as that of Matlock, or fuch as is found in all limeftone or marly countries. The calcareous earth in thefe waters might poffibly be carried to the bones, as madder is known to colour them. Warm bath. Volatile or fixed alkali as a lotion on the fpine, or effential oils. The innutrition of the bones is often firft to be per- ceived by the difficulty of breathing and palpitation of the heart on walking a little fafter than ufual, which I fuppofe is owing to the foftnefs of the ends of the ribs adjoining to the Sternum ; on which account they do not perfectly diftend the cheft, when they are raifed by the pectoral and intercoftal mufcles with greater force than -ufuah After this the fpine becomes curved both * Class I. 2. 2.] OF IRRITATION. 107 both by the foftnefs of its vertebre, and for the pur- pofe of making room for the difturbed heart. See Species 16 of this genus. As thefe patients are pale and weak, there would feem to be a deficiency of oxygene in thc:r blood, and in confequence a deficiency of phofphoric acid ; which is probably produced by oxygene in the act of ref- piration. Mr. Bonhome in the Chemical Annals, Auguft, 1793, fuppofes the rickets toarife from the prevalence of vegetable or acetous acid, which is known to foften bones out of the body. Mr. Dettaen feems to have efpoufed a Similar opinion, and both of them in con- fequence give alkalies and teftacea. If this theory was juft, the foft bones of fuch patients fliould Shew evident marks of fuch acidity after death; which I believe has not been obferved. Nor is it analogous to other animal facts, that nutritious fluids fecreted by the fineft veffels of the body fliould be fo little ani- malized, as to retain acetous or vegetable acidity. The fuccefs attending the following cafe in fo fliort a time as s. fortnight I afcribed principally to the ufe of the warm bath ; in which the patient continued for full half an hour every night, in the degree of heat, which was moft grateful to her fenfation, which might be I fuppofe about 94. Mifs-----, about ten years of age, and very tall and thin, has laboured under palpitation of her heart, and difficult breathing on the leaft exercife, with occasional violent dry cough, for a year or more, with dry lips, liitle appetite either rc& DISEASES [Class I. 2. 2. either for food or drink, and dry ikin, with cold ex- tremities. She has at times been occafionally worfe, and been relieved in fome degree by the bark. She began to bend forwards, and to lift up her fhoulders. 3The former feemed owing to a beginning curvature cf the fpine, the latter was probably caufed to facili- tate her difficult refpiration. M. M. She ufed the warm bath, as above related ; which by its warmth might increafe the irritability of the fmalleft feries of veffels, and by fupplying more moifture to the blood might probably tend to carry further the materials, which form calcareous or bony particles, or to convey them in more dilute folution. She took twice a day twenty grains of extract of bark, twenty grains of foda phofphorata, and ten grains of chalk, and ten of calcined hartfhorn mixed into a powder with ten drops of laudanum ; with flefh food both to dinner and fupper ; and port wine and water inftead of the fmall beer, She had been accuftomed to; fhe lay on a fofa frequently in a day, and occafionally ufed a neck-fwing. 15. Rachitis. Rickets. The head is large, pro- tuberant chiefly on the forepart. The fmaller joints are fwelled; the ribs depreffed; the belly tumid, with other parts emaciated. This difeafe from the innutrition or foftnefs of the bones arofe about two centuries ago; feems to have been half a century in an increafing or fpreading ftate ; continued about half a century at its height, or greateft diffufion ; and is Class I. 2.2-3 OF* IRRITATION. 109 now nearly vanifhed: which gives reafon to hope, that the fmall-pox, meafles, and venereal difeafe, which are all of modern production, and have already become milder, may in procefs of time vanifli from the earth, and perhaps be fucceeded by new ones! See the preceding fpecies. 16. Spina diftortio* Diftortion of the fpine is ano- ther difeafe originating from the innutrition or foft- nefs of the bones. I once faw a child about fix years old with palpitation of heart, and quicknefs of refpi- ration, which began to have a curvature of the fpine; 1 then doubted, whether the palpitation and quick refpiration were the caufe or confequence of the cur- vature of the fpine ; fufpecting either that nature had bent the fpine outwards to give room to the enlarged heart; or that the malformation of the cheft had com- preffed and impeded the movements of the heart. But a few weeks ago on attending a young lady about ten years old, whofe fpine had lately began to be distort- ed, with very great difficulty and quicknefs of refpi- ration, and alarming palpitation of the heart, I con- vinced myfelf, that the palpitation and difficult ref- piration were the effect of the change of the cavity of the cheft from the diftortion of the fpme; and that the whole was therefore a difeafe of the innutrition or foftnefs of the bones. For on directing her to lie down much in the day, and to take the bark, the diftortion became lefs, and tlie palpitation and quick refpiration became lefs at the 110 DISEASES - [Class!. 2.2, the fame time. After this obfervation a neck-fwing was directed, and flie took the bark, madder, and bone-afhes; and She continues to amend both in her Shape and health. Delicate young ladies are very liable to become awry at many boarding Schools. This is occafioned principally by their being obliged too long to preferve an erect attitude, by fitting on forms many hours to- gether. To prevent this the fohool-feats fhould have either backs, on which they may occafionally reft themfelves ; or defks before them, on which they nay occafionally lean. This is a thing of greater con- fequence than may appear to thofe, who have not at-. tended to it. When the leaft tendency to become awry is ob- ■fcrved, they fliould be advifed to lie down on a bed or fofa for an hour in the middle of the day for many months; which generally prevents the increafe of this deformity by taking off for a time the preffure on the foiiie of the back, and it at the fame time tends to make them grow taller. Young perfons, when nicely meafured, are found to be half an inch higher in a morning than at night; as is well known to thofe, who iniift very young men for foldiers. This is owing to the cartilages between the bones of the back becom- ing compreffed by the weight of the head and Shoul- ders on them during the day. It is the fame preffure which produces curvatures and distortions of the fpine in growing children, where the bones are fofter than ufual; and which ir.ay thus" be relieved by an horizontal Class I. 2. 2.3 OF IRRITATION. n* horizontal pofture for an hour in the middle of the day, or by being frequently allowed to lean on a chair, or to play on the ground on a carpet. Young ladies fliould alfo be directed, where two fleep in a bed, to change every night, or every week, their fides cf the bed ; which will prevent their ten- dency to fleep always on the fame fide; which is not only liable to produce crookednefs, but alfo to occafion difeafes by the internal parts being fo long kept in uni- form contact as to grow together. For the fame rea- fon they fliould not be allowed to fit always on the fame fide of the fire or window, becaufe they will then be inclined too frequently to bend themfelves to one fide. Another great caufe of injury to the Shape of young ladies is from the preffure of Stays, or other tight bandages, which at the fame time caufe other difeafes by changing the form or fituation of the internal parts. If a hard part of the Stays, even a knot of the thread, with which they are fewed together, is preffed hard upon one fide more than the other, the child bends from the Side moft painful, and thus occafions a cur- vature of the fpine. To counteract this effect fuch Stays, as have feweft hard parts, and efpecially fuch as can be daily or weekly turned, are preferable to others. Where frequent lying down on a fofa in the day- time, and Swinging frequently for a fhort time by the hands or head, with foofe drefs, do not relieve a be- ginning diftortion of the back ; recourfe may be had tit DISEASES [Class I. 2.2. to a chair with fluffed moveable arms for the purpofe of* fufpending the weight of the body by cufliions under the arm-pits, like refting on crutches, or like the leading firings of infants. From the top of the back of the fame chair a curved fteel bar may alfo project to fuf- pend the body occafionally, or in part by the head, like the fwing above mentioned. The ufe of this chair is more efficacious in Straightening the fpine, than Simply lying down horizontally ; as it not only takes off the preffure of the head and Shoulders from the fpine, but at the fame time the inferior parts of the body contribute to draw the fpine ftraight by their Weight; or laftly, recourfe may be had to a fpinal machine firft defcribed in the Memoires of the academy of forgery in Paris, Vol. III. p. 600, by M. Le Vacher, and fince made by Mr. Jones, at N° 6, North-ftreet, Tottenham-court Road, London, which fofpends the head, and places the weight of it on the hips. This machine is capable of improvement by joints in the bar at the back of it, to permit the body to bend forwards without diminifhing the extenfion of the fpine. The objections to this machine of M. Vacher, which Is made by Mr. Jones, are firft, that it is worn in the day-time, and has a very unfightly appearance. Mr. Jones has endeavoured to remedy this, by taking away the curved bar over the head, and Substituting in its place a forked bar, rifing up behind each ear, with webs faftened to it, which pafs under the chin and occiput. But this is not an improvement, but a de- j terioration Class I. 2. 2.] OF IRRITATIOM. n$ terioration of M. Vacher's machine, as it prevents the head from turning with facility to either fide. Another objection is, that its being worn, when the mufcles of the back are in action, it is rather calculated to pre- vent the curvature of the fpine from becoming greater, than to extend the fpine, and diminish is curvature. For this latter purpofe I have made a fteel bow, as defcribed in the annexed plate, which receives the head longitudinally from the forehead to the occiput; having a fork furnifhed with a web to fuftain the, chin, and another to fuftain the occiput. The fummit of the bow is fixed by a Swivel to the board going behind the head of the bed above the pillow. The bed is to be inclined from the head to the feet about twelve or Sixteen inches. Hence the patient would be conftantly Sliding down during fleep, unlefs fup- ported by this bow, with webbed forks, covered alfo with fur, placed beneath the chin, and beneath the occiput. There are alfo proper webs lined with fur for the hands to take hold of occafionally, and alfo to . go under the arms. By thefe means I fhould hope great advantage from gradually extending the fpine during the inactivity of the mufcles of the back; and that it may be done without disturbing the fleep of the patient, and if this Should happen, the bow is made to open by a joint at the fummit of it, fo as to be inftantly difengaged from the neck by the hand of the wearer. This bow I have not yet had oppor- tunity to make ufe of, but it may be had from Mr. Harrifon, whitefmith, Bridge-gate, Derby. I It ii* DISEASES [Class 1.1. 2, It will be from hence eafily perceived, that all other methods of confining or directing the growth of young people Should be ufed with great Skill y fuch as back- boards, or bandages, or Stocks for the feet; and that their application fliould not be continued too long at a time, left worfe confequences fhould enfue, than the deformity they were defigned to remove. To this may be added, that the ftiff erect attitude taught by fome modern dancing mafters docs not contribute to the grace of perfon, but rather militates againft ft; as is well feen in one of the prints in Hogarth's Analyfis of Beauty ; and is exemplified by the eafy grace of fome of theantient Statues, as. of the Venus de Medici, and the Antinous, and in the works of fome modern artifts, as in a beautiful print of Hebe feeding an Eagle, painted by Hamilton, and engraved by Egin- ton, and many of the figures of Angelica Kauffmam Where the bone of one of the vertebre of the back has been Swelled on both fides of it, fo as to become protuberant, iffues near the Swelled part have been found of great fervice, as mentioned in Species 18 of this genus. This has induced me to propofe in cur- vatures of the fpine, to put an iffue on the outfide of the curve, where it could be certainly afcertained, as the bones on the convex fide of the curve muft be en- larged ; in one cafe I thought thj^of fervice, and re- commend the further trial of it. In the tendency to curvature of the fpine, whatever Strengthens- the general constitution is of fervice -x as the ufe of the cold bath in the fummer months. This however Class I. 2.2.] OF IRRITATION. *i$ however requires fome restriction both in refpect to the degree of coldnefs of the bath, the time of continu- ing in it, and the feafon of the year. Common fprings, which are of forty-eight degrees of heat, are too cold for tender constitutions, whether of children or adults, and frequently do them great and irreparable injury* The coldnefs of river water in the Summer months, which is about fixty-eight degrees, or that of Matlock, which is about fixty eight, or of Buxton, which is eighty-two, are much to be preferred.. The time of continuing in the bath Should be but a minute or two, or not fo long as to occafion a trembling of the limbs from cold. In refpect to the feafon of the year, deli- cate children fliould certainly only bathe in the fum- mer months; as the going frequently into the cold air in winter will anfwer all the purpofes of the cojd bath. 17. Claudicatio coxaria. Lamenefs of the hip. A nodding of the thigh-bone is faid to be produced in feeble children by the foftnefs of the neck or upper part of that bone beneath the cartilage ; which is na- turally bent, and in this difeafe bends more down- wards, or nods, by the preffure of the body; and thus renders one leg apparently Shorter than the other. In other cafes the end of the bone is protruded out ofitsfocket, by inflammation or enlargement of the cartilages or ligaments of the joint, fo that it refts on fome part of the edge of the acetabulum, which in time becomes filled up. When the legs are Straight* I 2 as ir, :5S DISEASES [Class I. 2. 4. The promptitude of the membranes about the fcalp to fympathize with thofe of other parts of the fyftem is fo great, that this cephalea without fever, or quick- nefs of pulfe, is more frequently a fecondary than a primary difeafe, and then belongs to Clafs IV. 1.2. 11. The hemicrania, or partial head-ach, I believe to be almoft always, a difeafe from affociation ; though it is not impoffible, but a perfon may take cold on one fide of the head only. As fome people by fit- ting always on the fame fide of the fire in winter are liable to render one fide more tender than the other, and in confequence more Subject to pains, which have been erroncoufly termed rheumatic. See Clafs IV. 2. 1. 7. &8. M. M. The method of cure confifts in rendering the habit more robuft, by gentle conftant exercife in the open air, flefli diet, fmall beer at meals with one glafs of wine, regular hours of reft and rifing, and of meals. The cloathing about the head fliould be warmer during fleep than in the day ; becaufe at that time people are more liable to take cold; that is, the membranous parts of it are more liable to become torpid. As explained in Sect. XVIII. 15. In re, fpect to medicine, two drams of valerian root in pow- der three or four times a day are recommended by Fordyce. The bark. Steel in moderate quantities. An emetic. A blifter. Opium, half a grain .twice a day. Decayed teeth Should be extracted, par- ticularly fuch as either ache, or are ufelefs. Cold bath between 60 and 70 degrees of heat. Warm bath Class I. 2.4.] OF IRRITATION. 169 bath of 94 or 98 degrees every day for half an hour during a month. See Clafs IV. 2. 2. 7. and 8. A folution of arfenic, about the Sixteenth part of a grain, is reported to have great effect in this difeafe. It fhould be taken thrice a day, if it produces no grip- ing or ficknefs, for two or three weeks. A medicine of this kind is fold under the name of taftelefs ague- drops ; but a more certain method of afcertaining the quantity is delivered in the fubfequent materia mediea, Art. IV. 2. 6. 12. Odontalgia. Tooth-ach. The pain-has been crroneoufly fuppofed, where there is no inflammation, to be owing to fome acrid matter from a carious tooth ftimulating the membrane of the alveolar procefs into violent action and confequent pain; but the effect feems to have been mistaken for the caufe, and the decay of the tooth to have been occafioned by the torpor and confequent pain of the difeafed mem- brane. Firft, becaufe the pain precedes the decay of the tooth in regard to time, and is liable to recur, fre- quently for years, without certainly being fucceeded at laft by a carious tooth, as I have repeatedly ob- fcrved. Secondly, becaufe any Stimulant drug, as pyre- thrum, or oil of cloves, applied to the tooth, or eth^r applied externally to the cheek, fo far from increafing the pain, as they would do if the pained membrane, already -*?• DISEASES [Class I. 2. 4. ■ already acted too Strongly, that they frequently give immediate relief like a charm. And thirdly, becaufe the torpor, or deficient action of the membrane, which includes the difeafed tooth, occafions the morions of the membranes moft connect- ed with it, as thofe of the cheek and temples, to aCtv with lefs than their natural energy ; and hence a cold- nefs of the cheek is perceived eafily by the hand of the patient, comparing it with the other cheek; and the pain of the hemicrania is often produced in the temple of the affected fide. This coldnefs of the cheek in common tooth-ach evinces, that the pain is not then caufed by inflamma- tion ; becaufe in all inflammations fo much heat is pro- duced in the fecretions of new veflels and fluids, as to give heat to the parts in vicinity. And hence, as foon as the gum fwells and inflames along with the cheek, heat is produced, and the pain ceafes, owing to the increafed exertions of the torpid membrane, excited by the activity of the fenforial power of fenfation; which previoufly exifted in its paffive ftate in the. painful torpid membrane. See Odontitis, Clafs II. 1. 4. 7. and IV. 2. 2. 8. M. M. If the painful tooth be found, venefection. Then a cathartic. Afterwards two grains of opium. Camphor and opium, one grain of each held in the mouth ; or a drop or two of oil of cloves put on the painful tooth. Ether. If the tooth has a fmall hole in it, it Should be widened within by an instrument, and then Stopped with leaf-gold, or leaf-lead ; but fliould Class I. 2. 4.] OF IRRITATION. i7i fliould be extracted, if much decayed. It is probable that half a fmall drop of a ftrong folution of arfenic, put carefully into the hollow of a decayed aching tooth, would deftroy the nerve without giving any additional pain ; but this experiment requires great caution, left any of the folution fliould touch the tongue or gums. Much cold or much heat are equally injurious to the teeth, which are endued with a fine fenfation of this univerfal fluid. Itie belt method of preferring them is by the daily ufe of a brufh, which is not very hard, with warm water and fine charcoal dull. A lump of charcoal fhould be put a fecond time into the fire till it is red hot, as foon as it becomes cool the external afhes fhould be blown off, and it fhould be immediately reduced to fine powder in a mortar, and kept clofe flopped in a phial. It takes away the bad fmell from decayed teeth, by wafhing the mouth with this powder diffufed in water immediately. The putrid fmell of decaying Stumps of teeth iuay be de- stroyed for a time by waShing the mouth with a weak folution of alum in water. If the calcareous cruft upon the teeth adheres very firmly, a fine powder of pumice-ftone may be ufed occafionally, or a tooth in- strument. Acid of fea-falt, much diluted, may be ufed ; but this very rarely, and with the greateft caution, as in cleaning fea-fliells. When the gums are fpongy, they fliould be frequently pricked with a lancet. Should black fpots in teeth be cut out ? Does the enamel ■7* DISEASES ^Class I. *. 4. enamel grow again when it has been perforated or abraded? 13. Otalgia. Ear-ach fometimes continues many days without apparent inflammation, and is then fre- quently removed by filling the ear with laudanum, or with ether; or even with warm oil, or warm water. See Clafs II. 1. 4. 8. This pain of the ear, like hemicrania, is frequently the confequence of affocia- tion with a v difeafed tooth ; in that cafe the ether mould be applied to the cheek over the fufpected tooth, or a grain of opium and as much camphor mixed together and applied to the fufpeCted tooth. In this cafe the otalgia belongs to the fourth clafs of difeafes. 14. Pleurodyne chronica. Chronical pain of the fide. Pains of the membranous parts, which are not attend- ed with fever, have acquired the general name of rheumatic; which fhould, nevertheless, be restricted to thofe pains which exift only when the parts are in motion, and which have been left after inflammation of them ; as defcribed in Clafs I. 1, 3. 12. The pain of the fide here mentioned affects many ladies, and, may poffibly have been owing to the preffure of tight flays, which has weakened the action of the veffels compofing fome membranous part, as, like the cold head-ach, it is attended with prefent debility ; in one patient, a boy about ten years old, it was attended with daily convulfions, and was fuppofed to have ori- ginated from worms. The difeafe ia very frequent, and Clas* I. 2.4.] OF IRRITATION. I7j and generally withstands the ufe of blifters on the part; but in fome cafes I have known it removed by electric Shocks repeated every day for a fortnight through the affected fide. Pains of the fide fflay be fometimes occafioned by the adhefion of the lungs to the pleura, after an in- flammation of them; or to the adhefion of fome ab- dominal vifcera to their cavity, or to each other; which alfo are more liable to affect ladies from the un- natural And ungraceful preffure of tight Stays, or by fitting or lying too long in one pofture. But in thefe cafes the-pain fliould be more of the fmarting, than of the dull kind. M. M. Ether. A blifter. A plafter of Burgundy pitch. An iffue or feton on the part. Electric Shocks. Friction on the part with oil and camphor. Loofe drefs. Frequent change of pofture both in the day ftnd night. Internally opium, valerian, bark. 15. Sciatica frigida. • Cold fciatica* The pain along the courfe of the feiatie nerve, from the hip quite ctawft to the top of the foot, when it is not attended with fever, is improperly termed either rheumatifm or gout; as it occurs without inflammation, is attended with pain when the limb is at reft; and as the pain attends the courfe of the nerve, and not the courfe of the mufcles, or of the fafcia, which contains them. The theory of Cotunnius, who believed it to be a dropfy of the Sheath of the nerve, which was compreffed by the accumulated fluid, has not been- confirmed by dik feCtibn.. »74 DISEASES [Class I. 2.4 feCtion. The difeafe feems to confift of a torpor of this Sheath of the nerve, and the pain feems to be in confequence of this torpor. See Clafs II. 1. 2. 13. M. M. Venefection. A cathartic. And then one grain of calomel and one of opium every night for ten fucceffive nights. And a blifter, at the fame time, a little above the knee-joint on the outfide of the thigh, where the fciatic nerve is not fo deep feated. Warm bath. Cold bath. Cover the limb with oiled filk, or with a plafter-bandage of emplaftrum de minio. 16. Lumbago frigida. Cold lumbago. When no fever or inflammation attends this pain of the loins, and the pain exifts without motion, it belongs to this genus of difeafes, and refembles the pain of the Ioin3 in the cold fit of ague. As thefe membranes are ex- tenfive, and more eafily fall into quiefcence, either by fympathy, or when they are primarily affected,, this difeafe becomes very afflicting, and of great pertina- city. See Clafs IL 1. 2. 17. M. M. Venefection. A cathartic. Iffues on the loins. Adhefive plafter on the loins. Blifter on the os facrum. Warm bath. Cold bath. Remove to a warmer climate in the winter. Loofe drefs about the waift. Friction daily with oil and camphor.. 17. Hyfleralgia frigida. Cold pain of the uteru3 preceding or accompanying menftruation. It is attend- ed with cold extremities, want of appetite, and other marks of general debility. M.M. Class I. 2. 4.] OF IRRITATION. j7j M. M. A clyfter of half a pint of gruel, and 30 drops of laudanum ; or a grain of opium and fix grains of rhubarb every night. To fit over warm water, or go into a warm bath. 18. Proclalgia frigida. Cold pain at the bottom of the reClum previous to the tumour of the piles, which fometimes extends by fympathy to the loins; it feems to be fimilar to the pain at the beginning of menftruation, and is owing to the torpor or inirritabi- lity of the extremity of the alimentary canal, or to the obstruction of the blood in ifs%paffage through the liver, when that vifcus is affected, and its confequent delay in the veins of the rectum, occasioning tumours of them, and dull fenfations of pain. M. M. Calomel. A cathartic. Spice. Clyfter, with 30 drops of laudanum. Sitting over warm water. If chaiybeates after evacuation ? See Clafs I. 2. 3. 21. and I. 2. 1. 6. 19. Vefica fellea inirritabilitas. The inirritability of the gall-bladder probably occafions one kind of iclerus, or jaundice; which is owing to whatever ob- structs the paffage of bile into the duodenum. The jaundice of aged people, and which attends fome fevers, is believed to be moft frequently caufed by an irrita- tive palfy of the gall-bladder ; on which account the bile is not preffed from the cyft by its contraction, as in a paralyfis of the urinary bladder. A thick- i'i ■> DISEASES [Class I. 2. 4. A thickening of the coats of ilii common 'bile-duct by inflammation or increafed action of their veffels fo as to prevent the paffage of the bile into the inteftine, in the fame manner as the membrane, which lines the noftrils, becomes thickened in catarrh fo as to prevent the paffage of air through them, is probably another frequent caofe of jaundice*, efpecially of children ; and generally ceafes in about a fortnight, like a common catarrh, without the aid of medicine ; which has given rife to the character, which charms have obtained in fome countries for curing the jaundice of young people. The fpiffitiide of the bile is' another caufe of jaun- dice, as mentioned in Clafs I. 1. 3. 8. This alfo in children is a difeafe of little clanger, as the gall- ducts are diftenfible, and will the eafier admit of the exclufion of gall-ftofies; but becomes a more ferious difeafe m proportion to the age of the patient, and his habits of lire in refpect to fpirituous potation* A fourth caufe of jaundice is the compreffion of the bile-duct by the enlargement of an inflamed or fchir- rous liver ; this attends thofe who have drank much fpirituous liquor, and is generally fueeeeded by dropfy and death. M. M. Repeated emetics. Mild cathartics. Warm bath. Electricity. Bitters. Then fteel, which, wheti the pain and inflammation is removed by evacuations, aCts like a charm in removing the remainder of the in- flammation, and by promoting the abforption of til* new veffels or fluids; like the application of any acrid ever Class I. 2.4.] OF IRRITATION. I77 eye-water at the end of opthalmia; and thus the thickened coats of the bile-duct become reduced, or the enlargement of the liver leffened, and a free paf- fage is again opened for the bile into the inteftine. Ether with yolk of egg is recommended, as having a tendency to diffolve infpiffated bile. And a decoction of madder is recommended for the fame purpofe; be-* caufe the bile of animals, whofe food was mixed with madder, was found always in a dilute ftate. Aerated alkaline water, or Seltzer water. Raw cabbage, and other acrid vegetables, as water-creffes, muftard. Horfes are faid to be fubject to infpiffated bile, with yellow eyes, in the winter feafon, and to get well as foon as they feed on the fpring grafs. The largeft bile-Stone I have feen was from a lady, who had parted with it fome years before, and who had abstained above ten years from all kinds of vege- table diet to prevent, as fhe fuppofed, a colic of her ftomach, which was probably a pain of the biliary duct; on refuming the ufe of fome vegetable diet, She recovered a better ftate of health, and formed no new bilious concretions. A ftrong aerated alkaline water is fold by J. Schweppe, No. 8, King's-ftreet. Holborn. See Clafs I. 1. 3. 10. , 20. Pelvis renalis inirritabilitas. inirritability of the pelvis of the kidney. When the nucleus of a ftone, whether it be infpiffated mucus, or other mat- ter, is formed in the extremity of any of the tubuli N uriniferi. *7& DISEASES [Class I. 2. 5. uriniferi, and being detached from thence falls into the pelvis ' of the kidney, it is liable to lodge there from the want of due irritability of .the membrane ; and in that fituation increafes by new appofitions of in- durated animal matter in the fame manner as the ftone of the bladder. This is the general caufe of hemor- rhage from the kidney; and of obtufe pain in it on exercife;-or of acute pain, when the ftone advances into the ureter. See Clafs I. 1. 3. 9. ORDO II. Decreafed Irritation. GENUS V. Decreafed Aclion of the Organs of Senfe. SPECIES. 1. Stultitia inirritabilis. Folly from inirritability. Dulnefs of perception. When the motions of the fibrous extremities of the nerves of fenfe are too weak to excite fenfation with fufficient quicknefs and vigour. The irritative ideas are neverthelefs performed, though perhaps in a feeble manner, as fuch people do not run againft a poft, or walk into a well. There are three other kinds of folly ; that from deficient fenfation, from deficient volition, and from deficient affociation, as will be mentioned in their places. In delirium, re- verie, and fleep, the power of perception is abolished from other caufes. 2. Vtfus Class I. 2/5.] 0F IRRITATION. 179 2. Vifus imminutus. Diminifhed vifion. In our ap- proach to old age our vifion becomes imperfect, not only from the form of the cornea, which becomes lefs con- vex, and from its decreafed tranfparency mentioned in Clafs I. 2. 3. 26. ; but alfo from the decreafed irri- tability of the optic nerve. Thus, in the inirritative or nervous fever, the pupil of the eye becomes dilated ; which in this, as well as in the dropfy of the brain, is generally a fatal-fymptom. A part of the cornea as well as a part of the albuginea in thefe fevers is frequently feen during fleep ; which is owing to the inirritability of the retina to light, or to the general parefis of mufcular action, and in confequence to the lefs contraction of the fphincter of the eye, if it may bq fo called, at that time. There have been inftances of fome, who could not diftinguifh certain colours; and yet whofe eyes, in other refpeds, were not imperfect. Philof. Tranfact. Which feems to have been owing to the want of irri- tability, or the inaptitude to action, of fome claffes of fibres which compofe the retina. Other permanent defects depend on the difeafed ftate of the external organ. Clafs I. 1. 3. 14. I. 2. 3. 25. IV. 2. 1. 11. 3. Mufca volitantes. Dark fpots appearing before the eyes, and changing their apparent place with the motions of the eyes, are owing to a temporary defect of irritability of thofe parts of the retina, which have been lately expofed to more luminous objects than the oiher parts of it, as explained in Sect, XL. 2. Hence N 2 dark ito DISEASES [Class I. 2.5. dark fpots are feen on the bed-clothes by patients, when the optic nerve is become lefs irritable, as in fe- vers with great debility ; and the patients are perpe- tually trying to pick them off with their fingers to dif- cover what they arc ; for thefe parts of the retina of weak people are fooner exhaufted by the ftimulus of bright colours, and are longer in regaining their irri- tability. Other kinds of ocular fpeCtra, as the coloured ones, are alfo more liable to remain in the eyes of people debilitated by fevers, and to produce various halluci- nations of fight. For after the contraction of a muf- cle, the fibres of it continue in the laft fituation, till fome antagonist mufcles are exerted to retract them \ whence, when any one is much exhaufted by exercife, or by want of fleep, or in fevers, it is eafier to let the fibres of the retina remain in their laft fituation, after having been ftimulated into contraction, than to exert any antagonift fibres to replace them. As the optic nerves at their entrance into the eyes are each of them as thick as a crow-quill, it appears that a great quantity of fenforial power is expended during the day in the perpetual activity of our fenfe of vifion, befides that ufed in the motions of the eye- balls and eye-lids; as much I fuppofe as is expended in the motions of our arms, which are Supplied with nerves of about the fame diameters. From hence wc may conclude, that the light fhould be kept from pa- tients in fevers with debility, to prevent the unnecef- farv exhauftion of the fenforial power. And that on the lass I. 2. 5.] OF IRRITATION. ' i8j the fame account their rooms fhould be kept filent as well as dark ; that they fhould be at reft in an hori- zontal pofture ; and be cooled by a blaft of cool air, or by wafhing them with cold water, whenever their Skins are warmer than natural. 4. Strabifmus* Squinting is generally owing to one eye being lefs perfect than the other; on which ac- count the patient endeavours to hide the worft eye in the fhadow of the nofe, that his vifion by the other may not be confufed. Calves, which have an hyda- tide with infects enclofed in it in the frontal finus on one fide, turn towards the affected fide; becaufe the vifion on that fide, by the preffure of the hydatide, becomes lefs perfect; and the difeafe being recent, the animal turns round, expecting to get a more diftinet view of objects. In the hydrocephalus internus, where both eyes are not become infenfible, the patient fquints with only one eye, and views objects with the other, as in common Strabifmus. In this cafe it may be known on which fide the difeafe exifts, and that it does not exift on both fides of the brain ; in fuch circumftances, as the patients I believe never recover as they are now treat- ed, might it not be advifeable to perforate the era- mum over the ventricule of the affected fide ? which might at leaft give room'and ftimulus to the affected part of the brain ? M. M. If the fquinting has not been confirmed by long habit, and one eye be not much worfo than the N 3 other, I" DISEASES [Class I. 2.5. other, a piece of gauze ftretched on a circle of whale- bone, to cover the beft eyevin fuch a manner as to re- duce the diftinctnefs of vifion of this eye to a Similar degree of imperfection with the other, fliould be worn fome hours every day. Or the better eye fhould be totally darkened by a tin cup covered with black filk for fome hours daily, by which means the better eye will be gradually weakened by the want of ufe, and the worfe eye will be gradually ftrengthened by ufing it. Covering an inflamed eye in children for weeks together, is* very liable to produce fquinting, for the fame reafon, . 5. Amaurofis. Gutta ferena. Is a blindnefs from the inirritability of the optic nerve. It is generally efteemed a palfy of the nerve, but Should rather be deemed the death of it, as paralyfis has generally been applied to a deprivation only of voluntary power. This is a difeafe of dark eyes only, as the cataract is a difeafe of light eyes only. At the commencement of this difeafe, very minute electric Shocks fliould be repeatedly paffed through the eyes; fuch as may be produced by putting one edge of a piece of filver the fize of a half-crown piece beneath the tongue, and one edge of a piece of zinc of a fimilar fize between the upper lip and the gum, and then repeatedly bringing their exterior edges into contact, by which means very fmall electric fparks become vifible in the eyes. See additional note at the end of the firft vo- lume, p. $67. and Sect, XIV. 5. M. M. Mi- Class I. 2. 5."] OF IRRITATION. 183 M. M. Minute electric fliocks. A grain of opium, and a quarter of a grain of corrofive fublimate of. mercury, twice a day for four or fix weeks. Blif- ter on the crown of the head. 6. Auditus imminutus* Diminiflied hearing. Deaf- nefs is • a frequent fymptom in thofe inflammatory or fenfitive fevers with debility, which are generally called putrid; it attends the general ftupor in thofe fevers, and is rather efteemed a falutary Sign, as du- ring this ftupor there is lefs expenditure of fenforial power. In fevers of debility without inflammation, called nervous fevers, I fufpeCt deafhefs to be a bad fymp- tom, arifing like the dilated pupil from a partial pa- ralyfis of the nerve of fenfe. See Clafs IV. 2. 1. 15. Nervous fevers are fuppofed by Dr. Gilchrift to originate from a congestion of ferum or water in fome part of the brain, as many of the fymptoms are fo Similar to thofe of hydrocephalus internus, in which a fluid is accumulated in the ventricules of the brain; on this idea the inactivity of the optic or auditory nerves in thefe fevers may arife from the compreflion of the effufed fluid ; while the torpor attending pu- trid fever may depend on the meninges of the brain being thickened by inflammation, and thus compref- ling it; now the new veffels, or the blood, which thickens inflamed parts, is more frequently reabforb- ed, than the effufed fluid from a cavity ; and hence the ftupor in one cafe is lefs dangerous than in the other. N 4 In J«4 DISEASES [Class 1.2. 5. In inflammatory or fenfitive fevers' with debility, deafhefs may fometimes arife from a greater fecretion and abforption of the ear-wax, which is very fimilar to the bile, and is liable to fill the meatus audito- rius, when it is too vifcid, as bile obstructs the gall- ducts. M. M. In deafnefs without fever Dr. Darwin ap- plied a cupping-glafs on the ear with good effect, as defcribed in Phil. Tranf. Vol. LXIV. p. 348. Oil, ether, laudanum, dropped into the ears, 7. Olfaclus imminutus. Inactivity of the fenfe of fmell. From our habits of trufting to the art of cook- ery, and not examining our food by the fmell as other animals do, our fenfe of (mell is lefs perfeCt than theirs. See Sect. XVI. 5. Clafs IV. %. 1, 16. M. M, Mild errhines. 8. Giiftus imminutus. Want of tafte is very com- mon in fevers, owing frequently to the drynefs or fcurf of the tongue, or external organ of that fenfe, rather than to any injury of the nerves of tafte. See Clafs I. 1. 3. 1. IV. 2. 1. 16. M. M. Warm fubacid liquids taken frequently. 9. Taclus imminutus. Numbnefs is frequently com- plained of in fevers, and in epilepfy, and the touch is fometimes impaired by the drynefs of the cuticle of the fingers. See Clafs IV. 2, 1. 16. When Class I. 2. 5.} OF IRRITATION. 185 When the fenfe of touch is impaired by the com- preffion of the nerve, as in fitting long with one thigh croffed over the other, the limb appears larger, when we touch it with our hands, which is to be afcribed to the indiftinChiefs of the fenfation of touch, and may be explained in the fame manner as the apparent largenefs of objects feen through a mift. In this laft cafe the minute parts of an object, as fuppofe of a diftant boy, are feen lefs distinctly, and therefore we inftantly conceive them to be further from the eye, and in confequence that the whole fubtends a larger angle, and thus we believe the boy to be a man. So when any one's fingers are preffed on a benumbed limb, the fenfation produced is lefs'than it fliould be, judging from vifible circumftances; we therefore con- ceive, that fomething intervened between the objeCi: and the fenfe, for it is felt as if a blanket* was put be* tween them ; and that not being visibly the cafe, we judge that the limb is Swelled. The fenfe of touch is alfo liable to be deceived from the acquired habits of one part of it adlng in the vicinity of another part of it. Thus if the middle fin- ger be croffed over either of the fingers next to it, and a nut be felt by the two ends of the fingers fo croffed at the fame time, the nut appears as if it was two nuts. And laftly, the fenfe of touch is liable to be deceived by preconceived ideas ; which we believe to be excited by external objects, even when we are awake. It has happened to me more than onee, and I fup'pofe to moft others, to have put my hands into an i&6 . DISEASES [Class I. 2. 5-. an empty bafon Standing in an obfcure comer of a room to wafh them, which I believed to contain cold water, and have inftantly perceived a fenfation of warmth, contrary to that wdikh I expected to have felt. In fome paralytic affections, and in cold fits of ague, the fenfation of touch has been much impaired, and yet that of heat has remained. See Sect. XIV. 6. M. M. Friction alone, or with camphorated oil, warm bath. Ether. Volatile alkali and water. In- ternally fpice, fak. Incitantia. Secernentia. 10. Stupor. The ftupor, which occurs in fevers with debility, is generally efteemed a favourable fymp- tom ; which may arife from the lefs expenditure of fenforial power already existing in the brain and nerves, as mentioned in fpecies 6 of this genus. But if we fuppofe, that there is a continued production of fenforial power, or an accumulation of it in the torpid parts of-the fyftem, which is not improbable, becaufe fuch a production of it continues during Sleep, to which ftupor is much allied, there is Still further reafon for believing it to be a favourable fymptom in inirritable fevers; and that much injury is often done by blifters and other pow erful ftimuli to remove the ftupor. See Sect. XII. 7. 8. and XXXIII. 1. 4. Dr. Blane in his Croonian Lecture on mufcular mo- tion for 1788, among many other ingenious obferva- tions and deductions, relates a curious experiment on falmon, and other fifh, and which he repeated upon crh w ith fimilar event. "If Class I. 2. 5.] OF IRRITATION. 187 " If a fifli, immediately upon being taken out of the water, is ftunned by a violent blow on the head, or by having the head cruflied, the irritability and fweetnefs of the mufcles will be preferved much longer, than if it had been allowed to die with the organs of fenfe entire. This is fo well known to fifh- ermen, that they put it in practice, in order to make them longer fufceptible of the operation called crimp- ing. A falmon is one of the fifli leaft tenacious of life, infomuch, that it will lofe all figns of life in lefs than half an hour after it is taken out of the water, if fuffered to die without any farther injury ; but if, im- mediately after being caught, it receives a violent blow on the head, the mufcles will fhew vifible irrita- bility for more than twelve hours afterwards." Dr. Blane afterwards well remarks, that " in thofe diforders in which the exercife of the fenfes is in a great meafure destroyed, or fufpended, as in the hy- drocephalus, and apoplectic palfy, it happens not un- commonly, that the appetite and digeftion are better than in health." ORDO »88 DISEASES [Class t. 3. r. ORDO III. Retrograde Irritative Motion*. GENUS I. Of the Alimentary Canal. The retrograde motions of our fyftem originate either from defect of ftimulus, or from defect of irrita- bility. Thus ficknefs is often induced by hunger, which is a want of ftimulus; and from ipecacuanha, in which laft cafe it would feem,1 that the ficknefs was induced after the violence of the ftimulus was abated, and the confequent torpor had fucceeded. Hence fpice, opium, or food relieves ficknefs. The globus hyftericus, falivation, diabetes, and other inversions of motion attending hyfteric parox- yfms, feem to depend on the want of irritability of thofe parts of the body, becaufe they are attended with cold extremities, and general debility, and are relieved by wine, opium, fteel, and flefh diet; that is, by any additional ftimulus. When the longitudinal mufcles are fatigued by long action, or are habitually weaker than natural, the an- tagonist mufcles replace the limb by ftretching it in a contrary direction; and as thefe mufcles have had their actions affociated in Synchronous tribes, their actions ceafe together. But as the hollow mufcles pro- pel the fluids, which they contain, by motions affo- ciated in trains; when one ring is fatigued from its tpo great debility, and brought into retrograde action ; the Class I. 3. 1.] OF IRRITATION. 189 the next ring, and the next, from its affociation in train falls into retrograde action. Which continue fo long as they are excited to act, like the tremors of the hands of infirm people, fo long as they endeavour to- ad. Now as thefe hollow mufcles are perpetually 'ftimulated, thefe retrograde actions do not ceafe as the tremors of the longitudinal mufcles, which are gene- rally excited only by volition. Whence the retro- grade motions of hollow mufcles depend on two cir- cumstances, in which they differ from the longitudinal mufcles, namely, their motions being affociated in trains, and their being fubject to perpetual ftimulus. For further elucidation of the caufe of this curious fource of difeafes, fee Sect. XXIX. 11. 5. The fluids difgorged by the retrograde motions of the various vafcular mufcles may be distinguished, i. From thofe, which are produced by fecretion, by their not being attended by increafe of heat, which always accompanies increafed fecretion. 2. They may be diftinguifhed from thofe fluids, which are the confe- quence of deficient abforption, by their not poffeffing the faline acrimony, which thofe fluids poffefs ; which inflames the ikin or other membranes on which tliey fall; and which have a faline tafte to the tongue. 3. They may be diftinguifhed from thofe fluids, which are the confequence both of increafed fecretion and abforption, as thefe are attended with increafe of warmth, and are infpiffated by the abstraction of their aqueous parts. 4. Where chyle, or milk, are found in the feces or urine, or when other fluids, as matter, are i$0 DISEASES [Class 1.5. 1. are tranflated from one part of the fyftem to another, they have been the product of retrograde action of lymphatic or other canals. As explained in Sect. XXIX. 8. SPECIES. 1. Ruminatio. In the rumination of horned cattle the retrograde motions of the cefophagus are vifible to the eye, as they bring up the foftened grafs from their firft ftomach. The vegetable aliment in the firft ftomach of cattle, which have filled themfelves too full of young clover, is liable to run into fermentation, and diftend the ftomach, fo as to preclude its exit, and frequently to deftroy the animal. To difcharge this air the farmers frequently make an opening into the ftomach of the animal with fuccefs. I was inform- ed, I believe by the late Dr. Whytt of Edinburgh, that of twenty cows in this fituation two had died, and that he directed a pint of gin or whisky, mixed with an equal quantity of water, to be given to the other eighteen ; all of which eruCted immenfe quan- tities of air, and recovered. There are histories of ruminating men, and who have taken pleafure in the act of chewing their food a fecond time. Philof. TranfaCt. 2. Ruclus. Eructation. An inverted motion of the ftomach excluding through its upper valve an elaftic vapour generated by the fermentation of the aliment; which proceeds fo haftily, that the digeftive power does Class I.. 3- I-] OF IRRITATION. i9i does not fubdue it. This is fometimes acquired by habit, fo that fome people can eruct when they pleafe, and as long as they pleafe ; and there is gas enough generated to fupply them for this purpofe; for by Dr. Flak's experiments, an apple, and many other kinds of aliment, give up above fix hundred times their own bulk of an elaftic gas in fermentation. When people voluntarily eject the fixable air from their Stomachs, the fermentation of the aliment pro- ceeds the fafter ; for ftopping the veffels, which con- tain new wines, retards their fermentation, and open- ing them again accelerates it; hence where the di- geftion is impaired, and the ftomach fomewhat dif- tended with air, it is better to reftrain than to encou- rage eructations, except the quantity makes it necef- fary. When wine is confined in bottles the fermen- tation ftill proceeds flowly even for years, till all the fugar is converted into fpirit; but in the procefs of digeftion, the faccharine part is abforbed in the form of chyle by the bibulous mouths of the numerous laCteals, before it has time to run into the-vinous fer- mentation. 3. Apepfia. Indigeftion. Water-qualm. A few mouthfuls of the aliment are rejected at a time for fome hours after meals. When the aliment has had time to ferment, and become acid, it produces car- dialgia, or heart-burn. This difeafe is perhaps gene- rally left after a flight inflammation of the ftomach, called a furfcit, occafioned by drinking cold liquors, or i)t DISEASES [Class I. 3. I. or eating cold vegetables, when heated with exercife. This inflammation of the ftomach is frequently, I be- lieve, at its commencement removed by a critical eruption on the face, which differs in its appearance as well as in its caufe from the gutta rofea of drun- kards, as the ikin round the bafe of each eruption is lefs inflamed. See Clafs II. 1. 4. 7. This difeafe differs from Cardialgia, Clafs I. 2. 4. 5. in its being not uniformly attended with pain of the cardia ven- triculi, and from its retrograde motions of a part of the ftomach about the upper orifice of it. In the fame manner as hyfteria differs from hypochondriafis ; the one confifting in the weaknefs and indigeftion of the fame portions of the alimentary canal, and the other in the inverted motions of fome parts of it. This apepfia or water-qualm continues many years, even to old ape ; Mr. G-----of Lichfield fuffered under thn difeafe from his infancy ; and, as he grew old, found relief only from repeated dofes of opium. M. M. A blifter, rhubarb, a grain of opium twice a day. Soap, iron-powder. Tin-powder. 4. Vomitus. An inverted order of the motions of the ftomach and cefophagus with their abforbent vef- fels, by which their contents are evacuated. In the act of vomiting lefs fenforial powder is employed than in the ufual periftaltic motion of the ftomach, as ex- plained in Sect. XXXV. 1. 3. Whence after the operation of an emetic the digeftion becomes ftronger by an accumulation of fenforial power during its de- 4 creafed Class I. 3. !.] OF IRRITATION. i93 creafed action. This decreafed action of the Stomach may be either induced by want of ftimulus, as in the ficknefs which attends hunger ; or it may be induced by temporary wrant of irritability, as in cold fits of fever; or. from habitual want of irritability, as the vomiting of enfeebled drunkards. Or laftly, by ha- ving been previously too violently ftimulated by an emetic drug, as by ipecacuanha. M. M. A blifter. An emetic. Opium. Warmth of a bed, covering the face for a while with the bed- clothes. Crude mercury. A poultice with opium or theriaca externally. 5. Cholera.. When not only the ftomach, as in the laft article, but alfo the duodenum, and ilium, as low as the valve of the colon, have their motions invert- ed ; and great quantities of bile are thus poured into the ftomach; while at the fame time fome branches of the laCteals become retrograde, and difgorge their con- tents into the upper part of the alimentary canal; and other branches of them difgorge their contents into the lower parts of it beneath the valve of the colon; a vomit- ing and purging commence together, which is called cho- lera, as it is fuppofed to have its origin from increafed fecretion of bile ; but I fuppofe more frequently arifes from putrid food, or poifonous drugs, as in the cafe narrated in Sect. XXV. 13. where other circumstances of this difeafe are explained. • See Clafs II. 1.2. 11. The cramps of the legs, which are liable to attend cholera, are explained in Clafs III. 1. 1* i£U- O 6 Ileus. 194 DISEASES [Class I. 3. 1. 6. Ileus. Confifts in the inverted motions of the wfiole inteftinal canal, from the mouth to the anus; and of the laCteals and abforbents which arife from it. In this pitiable difeafe, through the valve of the colon, through the pylorus, the cardia, and the, pharinx, are ejected, firft, the contents of the ftomach and in- teftines, with the excrement and even clyfters them- felves ; then the fluid from the laCteals, which is now poured into the inteftines by their retrograde motions, is thrown up by the mouth ; and, laftly, every fluid, which is abforbed by the other lymphatic branches, from the cellujar membrane, the Skin, the bladder, and all other cavities of the body; and which is then poured into the ftomach or inteftines by the retro- grade motions of the laCteals; all which fupply that amazing quantity of fluid, which is in this difeafe con- tinually ejected by vomiting. See Sect. XXV. 15. for a further explanation of this difeafe. M. M. Copious venefection. Twenty grains of calomel in fmall pills, or one grain of aloe every hour till ftools are procured. Blifters. Warm bath. Crude mercury. Clyfter of ice-water. Smear the ikin all over with greafe, as mentioned in Sect. XXV. 15. As this malady is occafioned fometimes by an in- trofufception of a part of the inteftine into another part of it, efpecially in children, could holding them up by their heels for a fecond or two of time be of fervice after venefection ? Or the exhibition of crude quickfilver two ounces every half hour, till a pound is taken, .be .particularly ferviceable in this circum- ftance ? Claw I. 3. 1.] OF IRRITATION. i95 Stance ? Or could half a pound, or a pound, of crude mercury be injected as a clyfter, the patient being elevated by the knees and thighs fo as to have his head and fhoulders much lower than his bottom, or even for a Short time held up by the heels ? Could this alfo be of advantage in Strangulated hernia ? Where the difeafe is owing to Strangulated hernia, the part fhould be fprinkled with cold water, or iced water, or fait and water recently mixed, or moiftened with ether. In cafes of Strangulated hernia, could acupuncture, or punCture with a capillary trocar, be ufed with fafety and advantage to give exit to air contained in the Strangulated bowel ? Or to Stimulate it into action ? It is not uncommon for bafhful men to conceal their being afflicted with a fmall hernia, which is the caufe of their death; this circumftance fliould therefore always be enquired into. Is the feat or caufe of the ileus always below the valve of the colon, and that of the cholera above it? See Clafs II. 1. 2. 11, 7. Globus hyflericus. Hyfteric fuffocation is the per- ception of a globe rolling round in the abdomen, and afcending to the ftomach and throat, and there in- ducing ftrangulation. It confifts of an ineffectual in- verfion of the motions of the cefophagus, and other parts of the alimentary canal; nothing being rejected from the ftomach. M. M. Tincture of caftor. TinCt. of opium of each 15 drops. See Hyfteria, Clafs I. 3. 1. 9. O 2 8. Vomendi 196 DISEASES [Class I. j. r. 8. Vomtndi conamen inane. An ineffectual effort to vomit. It frequently occurs, when the ftomach it empty, and in fome cafes continues many hours ; but as the lymphatics of the ftomach are not inverted at the fame time, there is no fupply of materials to be ejected; it is fometimes a fymptom of hyfteria, but more frequently attends irregular epilepfies or re- veries ; which however may be diftinguiflied by their violence of exertion, for the exertions of hyfteric mo- tions are feeble, as they are caufed by debility ; but thofe of epilepfies, as they are ufed to relieve pain, are of the moft violent kind; infomuch that thofe who have once feen thefe ineffectual efforts to vomit in fome epilepfies, can never again miftake them for fymptoms of hyfteria. See a cafe in Sect. XIX. 2. M. M. Blifter. Opium. Crude mercury. 9. Borborigmus. A gurgling of the bowels pro- ceeds from a partial invertion of the periftaltie motions of them, by which the gas is brought into a fuperior part of the bowel, and bubbles through the defcend- ing fluid, like air ruffling into a bottle as the water is poured out of it. This is fometimes a diftreffing fymptom of the debility of the bowels joined with a partial inverfion of their motions. . I attended a young lady about Sixteen, who was in other refpeCts feeble, whofe bowels almoft inceffantly made a gurgling noife fo loud as to be heard at a considerable diftance, and to attract the notice of all who w ere near her. As this noife never ceafed a minute together for many hours Class 1-3. i-3 OF IRRITATION. 1^7 hours in a day, it could not be produced by the uni- form defcent of water, and afcent of air through it, but there muft have been alternately a retrograde movement of a part of the bowel, which muft again have puflied up the water above the air; or which might raife a part of the bowel, in which the fluid was lodged, alternately above and below another portion of it; which might readily happen in fome of the curvatures of the fmallef inteftines, the air in which might be moved backward and forward like the air-bubble in a glafs-level. M. M. Effential oil. Ten corns of black pepper fwallowed whole after dinner, that its eifect might be flower and more permanent; a fmall pipe occafionally introduced into the rectum to facilitate the efcape of the air. Crude mercury. See Clafs I. 2. 4. 9. 10. Hyfleria. The three laft articles, together with the lymphatic diabetes, are the moft common fymptoms of the hyfteric difeafe; to which fometimes is added the lymphatic falivation, and fits of fyncope, or convulfion, with palpitation of the heart (which probably confifts of retrograde motions of it), and a great fear of dying. Which laft circumftance diftin- guifhes thefe convulfions from the epileptic ones with greater certainty than any other fingle fymptom. The pale copious urine, cold ikin, palpitation, and trem- bling, are the fymptoms excited by great fear. Hence in hyfteric difeafes, when thefe fymptoms occur, the fear, which has been ufually affociated with them, O 3 recurs 198 DISEASES [Class I. 3 1. recurs at the fame time, as in hypochondriafis, Clafs I. 2. 4. 10. See Sect XVI. 8. 1. The convulfions which fometimes attend the hyfteric difeafe, are exertions to relieve pain, either of fome torpid, or of fome retrograde organ ; and in this re- fpect they refemble epileptic convulfions, except that they are feldom fo violent as entirely to produce in- fenfibility to external ftimuli; for thefe weaker pains ceafe before the total exhauftion of fenforial power is produced, and the patient finks into imperfect Syn- cope ; whereas the true epilepfy generally terminates in temporary apoplexy, with perfect infenfibility to external objects. Thefe convulfions are lefs to be dreaded than the epileptic ones, as they do not ori- ginate from fo permanent a caufe. The great difcharge of pale urine in this difeafe is owing to the inverted motions of the lymphatics, which arife about the neck of the bladder, as de- fcribed in Sect. XXIX. 4. 5. And the lymphatic falivation arifes from the inverted motions of the fali- Tary lymphatics. Hyfteria is diftinguifhed from hypochondriafis, as in the latter there are no retrograde motions of the ali- mentary canal, but fimply a debility or inirritat^Jity of it, with diftention and flatulency. It is diftinguifli- ed from apepfia and cardialgia by there being nothing ejected from the ftomach by the retrograde motions of it, or of the cefophagus. M. M. Opium. Camphor. Afafcetida. Caftor, with finapifms externally ; to which muft be added a clyfter of Class I. 3.1.] OF IRRITATION. 199 of cold water, or iced water; which according to Monf. Pomme, relieves thefe hyfteric fymptoms in- Slantaneoufly like a charm; which it may effect by checking the inverted motions of the inteftinal canal by the torpor occafioned by cold ; or one end of the inteftinal canal may become ftrengthened, and regain its periftaltic motion by reverfe fympathy, when the other end is rendered torpid by ice-water. (Pomme des Affections Vaporeufes, p. 25.J Thefe remove the prefent fymptoms; and bark, fteel, exercife, coldifh bath, prevent their returns. See Art. VI. 2. 1, 11. Hydrophobia. Dread of water occafioned by the bite of a mad dog, is a violent inverfion of the motions of the cefophagus on the contact or even approach of water •r other fluids. The pharinx feems to have acquired the fenfibility of the larinx in this difeafe, and is as impatient to reject any fluid, which gets into it. Is not the cardia ventriculi the feat of this difeafe ? As in cardialgia the pain is often felt in the pharinx, when the acid material Stimulates the other"end of the canal, which terminates in the ftomach. As this fatal difeafe refembles tetanus, or locked jaw, in its tendency to convulfion from a diftant wound, and' affeCts fome other parts by affociation, it is treated of in Clafs III. 1. 1. 15. and IV. 2. 1. 7. 04 ORDO 20© DISEASES [Class I. 3. 2, ORDO III. Retrograde Irritative Motions, GENUS II. Of the Abforbent Syfiem. SPECIES. I* Catarrhus lymphaticus. Lymphatic catarrh. A periodical defluxion of a thin fluid from the noftrils, for a few hours, occafioned by the retrograde motions of their lymphatics; which may probably be fupplied with fluid by the increafed abforption of fome other lymphatic branches in their vicinity. It is diftinguifh- ed from that mucous difcharge, which happens in frofty weather from decreafed abforption, becaufe it is lefs fait to the tafte ; and from an increafed fecretion of mucus, becaufe it is neither fo vifcid, nor is attend- ed with heat of the part. This complaint is liable to recur at diurnal periods, like an intermittent fever, for weeks and months together, with great fneezing and very copious difcharge for an hour or two. I have feen two of thefe cafes, both of which oc- curred in delicate women, and feemed an appendage to other hyfteric fymptoms; whence I concluded, that the difcharge was occafioned by the inverted mo- tions of the lymphatics of the noftrils, like the pale urine in hyfteric cafes; and that they might receive this fluid from fome other branches of lymphatic veffels opening into the frontal or maxillary cavities in their vicinity, Could Class I. 3.2.] OF IRRITATION. 201 Could fuch a difcharge be produced by ftrong er- rhines, and excite an abforption of the congestion of lymph in the dropfy of the brain ? 2. Salivatio lymphatica. Lymphatic falivation. A copious expuition of a pellucid infipid fluid, occafioned by the retrograde motions of the lymphatics of the mouth. It is fometimes periodical, and often attends the hyfteric difeafe, and nervous fevers ; but is not accompanied with a faline tafte, or with heat of the mouth, or naufea. 3. Naufea hwnida. Moift naufea confifts in a dif- charge of fluid, owing to the retrograde motions of the lymphatics about the fauces, without increafe of heat, or faline tafte, together with fome retrograde motions of the fauces or pharinx ; along with this naufea a ficknefs generally precedes the act of vomit- ing ; which may confift of a fimilar difcharge of mucus or chyle into the ftomach by the retrograde motions of the lymphatics or laCteals, which open into it. See Clafs I. 2. 4. 3. and 1, 2. 4. 4. M. M. Subacid liquids. Wine. Opium. A blifter. 4. Diarrhoea lymphatica. Lymphatic diarrhcea. A quantity of mucus and lymph are poured into the in- teftines by the inverted motions of the inteftinal lym- phatics. The feces are lefs fetid and more liquid; and it fometimes portends the commencement of a di- abetes, or dropfy, or their temporary relief. This lymphatic ** za DISEASES [Class I. 3. 2. lymphatic diarrhcea fometimes becomes chronical, in which the atmofpheric moifture, abforbed by the cu- taneous and plumonary lymphatics, is poured into the inteftines by the retrograde motions of the laCteals See Section XXIX. 4. 6. where fome cafes of this kind are related. 5. Diarrhoea chylifera, caliaca. Chyliferous diarrhcea. The chyle drank up by the laCteals of the upper in- teftines is poured into the lower ones by the retrograde motions of their laCteals, and appears in the dejeCtions. This circumftance occurs at the beginning of diarrhcea crapulofa, where the patient has taken and digefted more aliment than the fyftem can conveniently receive, and thus eliminates a part of it; as appears when there is curdled chyle in fome of the dejections. Sec Sect. XXIX. 4. 7. It differs from the lymphatic diarrhcea, as the chyliferous diabetes differs from the aqueous and mucaginous diabetes. 6. Diabafes* By the retrograde motions of the urinary lymphatics, an immenfe quantity of fluid is poured into the bladder. It is either termed chyli- ferous, or aqueous, or mucaginous, from the nature of the fluid brought into the bladder; and is either a temporary difeafe, as in hyfteric women, in the beginning of intoxication, in worm cafes, or in thofe expofed to cold damp air, or to great fear, or anxi- ety, or in the commencement of fome dropfies; or it becomes chronical. When Class 1.3.2.] OF IRRITATION. 203 When the urinary lymphatics invert their motions, and pour their refluent contents into the bladder, fome other branch of the abforbent fyftem acts with greater energy to fupply this fluid. If it is the in- teftinal branch, the chyliferous diabetes is produced: if it is the cutaneous or pulmonary branch, the aque-. ous diabetes is produced : and if the cellular or cyf- tic branches, the mucaginous diabetes. In the two laft the urine is pellucid, and contains no fugar. In dropfies the fluid is fometimes abforbed, and poured into the bladder by the retrograde motions of the urinary lymphatics, as during the exhibition of digitalis. In the beginning of the dropfies of infirm gouty patients, I have frequently obferved, that they make a large quantity of wrater for one night, which relieves them for feveral days. In thefe cafes the patient previoufly feels a fulnefs about the precordia, with difficult refpiration, and fymptoms fimilar to thofe of hyfteria. Perhaps a previous defect of abforption takes place in fome part of the body in thofe hyfteric cafes, which are relieved by a copious difcharge of pale urine. See Diabetes explained at large, Section XXIX. 4. A difcharge of blood fometimes attends the dia- betes, which was occafionally a fymptom of that dif- eafe in Mr. Brindley, the great navigable canal maker in this country. Which may be accounted for by the communication of a lymphatic branch with the gaftric branch of the vena portarum, as difcovered by J, F. Meckel. See Section XXVII. 2. M. M. Alum. 204 DISEASES [Class I. 3. 2. M. M. Ahim. Earth of Alum. Cantharides. Calo- mel. Bark. Steel. Rofin: Opium. See Sect. XXIX. 4. 7. Sudor lymphaticus. Profufe fweats from the in- verted motions of the cutaneous lymphatics, as in fome fainting fits, and at the approach of death; and as perhaps in the fudor anglicanus. See Sect. XXIX. 5. Thefe fweats are glutinous to the touch, and without increafed heat of the fkin; if the part is not covered, the fkin becomes cold from the eva- poration of the fluid. Thefe fweats without heat Ibmetirnes occur in the act of vomiting, as in Sect. XXV. 9. and are probably the caufe of the cold fweaty hands of fome people. As mentioned in Sect. XXIX. 4. 9. in the cafe of R. Davis, which he cured by frequent application of lime. Though it is pot fible, that cold fweaty hands may alfo arife from the want of due abforption of the perfpirable matter ef- fbfed on them, and that the coldnefs may be owing to the greater evaporation in confequence. The acid fweats defcribed by Dr. Dobfon, which he obferved in a diabetic patient, and afcribes to the chyle effufed on the fkin, muft be afcribed to the retrograde action of the cutaneous lymphatics. See Sect. XXIX. 6. 8, Sudor afthmcrticus. The cold fweats in this dif- eafe only cover the head, arms, and breaft, and are frequently exceedingly profufe. Thefe fweats are owing Class I. 3. 2. J OF IRRITATION. ^5 owing to the inverted motions of the cutaneous lym- phatics of the upper part of the body, and at the fame time the increafed abforption of the pulmonary abforbents: hence thefe fweats when profufe relieve the prefenj fit of afthma. There is no other way to account for fweats appearing on the upper parts of the body only, but by the fluid having been abforbed by the lymphatic branch of the lungs, and effufed on the ikin by the retrograde movements of the cutane- ous lymphatics ; which join thofe of the lungs before they enter into the venous circulation. For if they were occafioned, as generally fuppofed, by the diffi- culty of the circulation of the blood through the lungs, the whole ikin muft be equally affected, both of the upper and lower parts of the body; for whatever eould obftruCt the circulation in the upper part of the venous fyftem, muft equally obstruct it in the lower part of it. See Sect. XXIX. 6. In the convulfivc afthma thefe fweats do not occur ; hence they may be diftinguifhed; and might be called the hydropic afthma, and the epileptic afthma. 9. Tranflatio puris. Translation of matter from cne part of the fyftem to another can only be explain- ed from its being abforbed by one branch of the lym- phatic fyftem, and depofited in a diftant part by the retrograde motions of another branch ; as mentioned Sect. XXIX. 7. 1. It is curious, that thefe transla- tions of matter are attended generally, I believe, with cold fits; for lefs heat is produced during the retro- grade \ s»6 DISEASES [Class 1.3. 2. grade action of this part of the fyftem, as no fecretion in the lymphatic glands, of the affected branches can exift at the fame time. Do any ineffectual retrograde motions occafion the cold fits. of agues ? The time when the gout of the liver ceafes, and the gout in the foot commences, is attended with a cold fit, as I have obferved in two inftances, which is difficult to explai% without fuppofing the new veffels, or the matter pro- duced on the inflamed liver, to be abforbed, and cither eliminated by fome retrograde motion, or carried to the newly inflamed part ? See Clafs IV. 1. 2. 15. 10. Tranflatio laclis. Tranflation of milk to the bowels in puerperal fevers can only be explained by the milk being abforbed by the pectoral branch of lymphatics, and carried to the bowels by the retro- grade motions of the inteftinal lymphatics or laCteals. See many inftances of this in Sect. XXIX. 7. 4. ii. Tranflatio urina. Tranflation of urine. There is a curious cafe related in the Tranfactions of the Col- lege of Phyficians at Philadelphia, Vol. I. p. 96. of a girl, who labouring under an ifcuria vomited her urine for many months; which could not be diftinguifhed from that which was at other times drawn off by the catheter. After having taken much opium, She feems at length to have formed gravel, fome of which was frequently brought up by vomiting. Dr. Senter afcribes this to the retrograde motions of the lympha- tics of the Stomach, and the increafed ones, of thofe of a the Class I. 3. 3.] OF IRRITATION. 20; the bladder, and refers to.thofe of Sect. XXIX. of this work ; which feCtion was firft publifhed in 1780; and to Macquire's Dictionary of Chemifiry, Art. Urine. The patient above defcribed fometimes had a dif- eharge of urine by the navel, and at other times by jjae rectum, and fometimes by urinous fweats. ORDO III. Retrograde Irritative Motions* GENUS III. Of the Sanguiferous Sy/iem* SPECIES. 1. Capillarium motus retrogreffus. In microfcopic experiments it is ufual to fee globules of blood regur- gitate from the capillary veffels again and again, be- fore they pafs through them; and not only the meuths of the veins, which arife from thefe capillaries, are frequently feen by microfcopes to regurgitate fome particles of blood during the Struggles of the animal; but a retrograde motion of the blood in the veins of thefe animals, from the very heart to the extremities ef the limbs, is obfervable by intervals during the dif- treffes of the dying creature. Haller, Elem. Phyf. T. i. p. 216. See Section XXIX. 3. 8. 2. Palpitaili 208 DISEASES [Class I. 3.3. 1* Palpitatio cordis. May not the ineffectual and weak unequal motions of the heart in hyfteric cafes be afcribed to the retrograde motions of it, which continue for a fhort time, or terminate in fyncope ? See Clafs IV. 3. 1. 6. 3. Anhelatio fpafmodica. In fome afthmas may not the difficulty of refpiration arife from the inverted action of the finer branches of the bronchia, or of the pulmonary artery or vein, like thofe of the capillaries above defcribed in No. r. of this genus ? t THE Class II.] OF IRRITATION. 209 THE ORDERS AND GENERA OF THE SECOND CLASS OF DISEASES. CLASS II. DISEASES OF SENSATION. ORDO I. Increafed Senfation. GENERA. 1. With increafed action of the mufcles. 2. With the production of new veffels by internal membranes or glands with fever. 3. With the production of new veffels by external membranes or glands with fever. 4. With the production of new veffels by internal membranes or glands without fever. 5. With the production of new veffels by external membranes or glands without fever. 6. With fever confequent to the production of new veffels or fluids. 7. With increafed action of the organs of fenfe. ORDO II. Decreafed Senfation. GENERA. 1. With decreafed actions of the general fyftem. :'. With decreafed actions of particular organs. P ORDO *ro DISEASES [Class II. i.t. ORDO III. Retrograde Senfitive Motions. GENERA. i. Of the arterial fyftem. 2. Of the abforbent fyftem. 3. Of the excretory dncts. THE ORDERS, GENERA, AND SPECIES, OF THE SECOND CLASS OF DISEASES. CLASS II. DISEASES OF SENSATION. ORDO I. Increafed Senfation* GENUS I. With Increafed Aclion of the Mufcles. SPECIES. 1, Deglutitio. Deglutition. 2. Refpiratio. Refpiration. 3. Sternutatio. Sneezing. 4. Anhelitus. Panting. 5. Tuffs ebriorum. Cough of inebriates. §". Singultus. Hiccough. 7. Afthmr Class II. i. 2.] OF SENSATION. 7. Aflhma humcrale. Humoral afthma. 8. Niclitatio fenfitiva. Winking from pain. 9. Ofcitatio et pandiculatio. Yawning and ftretching. 10. Tenefmus. Tenefmus. 11. Stranguria. Strangury. 12. Parturitio. Parturition. 211 GENUS II. With the Produclion of new Veffels by internal Membranes or Glands, with Fever.. SPECIES. 1. Febris fenfitiva irritata. Senfitive irritated fever. 2. Ophthalmia interna. Inflammation of the eye. 3. Phrenitis.------------of the brain. 4. Peripneumonia. ------------of the lungs. ------------trachealis.------------the croup. ------------of the pleura. ------------of the dia- 5. Pleuritis. $. Diaphragmitis. 7. Carditis. 8. Peritonitis. 9. Mefenteritis. 1 o. Gaflritis. 11. Enteritis. 12. Hepatitis. 1 3. Splenitis. phragm. of the heart. of the perito- neum. tery. mach. P 2 — of the mefen- — of the fto- of the bowels. of the liver. of the fpleen. 14. Nephritis* 2iz DISEASES [Class II. i. j. 14. Nephritis, Inflammation of the kidney. 15. Cyflitis.------------of the blad- der. 16. Hyfleritis.------------of the womb. 17. Lumbago fenfitiva. --------.---of the loins. 18. Ifchias* ----------— of the pelvis. 19. Paronychia interna* ----------- beneath the nails. GENUS III. With the Produclion of new Veffels by external Membranes or Glands, with Fever. SPECIES. 1. Febris fenfitiva inirri- Senfitive inirritated fever. tata. 2. Eryfipelas irritatum. Eryfipelas irritated. ---------inirritatum.----------inirritated. ---------fenfitivum----------fenfitive. 3. Tonfillitis interna. Angina internal. ---------fuperficialis* -------» fuperficial. ---------mirritata. -------inirritated. 4. Parotitis fuppurans. Mumps fuppurativc. --------mutabilis.------ mutable. --------felina.------of cats. 5. Catarrhus fenfitivus. Cattarrh inflammatory. 6.----------contagiofus.--------eontaglous, ----------equinus et ca---------among horfes and ninus. dogs. 7. Peripneumonia fuperfi- Superficial peripneumony. - c'w.lis. 8. Per- Class II. i. 3.] OF SENSATION. 8. Pertuffis. 9. Variola difcreta. ------confiuens. -------inoculata. 1 o. Rubeola irritata. -------- inirritata. 213 11. Scarlatina mitis. ----------maligna. 12. Miliaria fudatoria. \--------irritata. --------inirritata. i3.Peflis. vaccina. 14. Pemphigus. 15. Varicella. 16. Urticaria. 17. Apth a fenfitiva. ------irritata. ------inirritata. 18. Dyfenteria. 19. Gaftritis fuperficialis. 20. Enteritis fuperficialis. Chin-Cough. Small-pox diftinct. ----------confluent. ----------inoculated. Meafles irritated. --------Inirritated. Scarlet fever mild. ------malignant. Miliary fever fudatory. --------irritated. —------inirritated. Plague. of horned cattle. Bladdery fever. Chicken-pox. Nettle rafh. Thrufh fenfitive. --------irritated. ■-------inirritated. Bloody flux. Superficial inflammation of the ftomach. ------------------------of the bowels. P3 GENUS 2i4 BISEASES [Class II. i. 4. GENUS IV. With the Production of new Veffels by internal Membranes or Glands, without Fever. SPECIES. 1. Ophthalmia fuperficialis. Ophthalmy fuperficial. ----------lymphatica. ■ ■ - lymphatic. ----------equina.----------of horfes, 2. Pterigion. Eye-wing. 3. Tarfitis palpebrarum* Red eyelids, 4. Hordeolum. Stye. 5. Paronychia fuperficialis. Whitlow. 6. Gutta rofea hepatica* Pimpled face hepatic. ----------fiomatica* ----«— ftomatic. ---------- hereditaria. > ■ hereditary, 7. Odontitis. Inflamed tooth. 8. Otitis. --------ear. 9. Fiflula lacrymalis. Fiftula lacrymalis, 10. Fiflula in ano Fiftula in ano. 11. Hepatitis chronica. Chronical hepatitis, 12. Scrophula fuppurans. Suppurating fcrophula, 13. Scorbutus fuppurans. Suppurating fcurvy. 14. Schirrus fuppurans. Suppurating fchirrus. 15. Carcinoma. Cancer. 16. Arthrocele. Swelling of the joints. 17. Arthropuofis. Suppuration of the joints. 18. Caries offium. Caries of the bones. GENUS Class II. i. 6.] OF SENSATION. *»5 GENUS V. With the Preduclhn of new Veffels by external Membranes or Glands, without Fever* SPECIES. i. Gonorrhoea venerea. Clap. 3. Syphilis* Venereal difeafe. 3. Lepra* Leprofy. 4. Elephantiafis* Elephantiafis. 5. Framboefia. Framboefia. 6. Pfora. Itch, 7. Pfora ebriorum. Itch of drunkards. 8. Herpes. Herpes. 9. Zona ignea. Shingles. 10. Annulus repens. Ring-worm. 11. Tinea capitis. Scald-head. 12. Crufta laclea. Milk-cruft. 13. Trichoma. Plica polonica. GENUS VI. With Fever confequent to the Produclion of new Veffels or Fluids. SPECIES. 1. Febris fenfitiva. Senfitive fever. 2.-----a pure claufo* Fever from concealed mat- ter. 3.-----a vomica.-----from vomica. 4.-----ab empyemate.-----from empyema. 5. — mefenterica*-----mefenteric. P 4 6, Febris 216 DISEASES [Class II. i. 7. 6. Febris a pure aerato. Fever from aerated matter. 7''-----& phthifi.-----from confumption. 8------ fcrophulofa.-----fcrophulous. 9------ifchiadica.-----from ifchias. 10.-----arthropuodica*-----from joint-evil. 11.-----a pure contagiofo.-----from contagious mat- ter. 12.-----variolofafecunda------fecondary of fmall- ria. pox. 13.-----carcinomatofa.-----cancerous. 14.-----venerea. -----venereal. *5«-----afanie contagiofa.-----from contagious fa- mes. 16. - puerpera. -----puerperal. 17* — afphacelo*-----from fphacelus. GENUS VII. With increafed Aclion of the Organs of Senfe. SPECIES. I. Delirium febrile. Delirium of fevers. 2.-------maniacale.-------maniacal 3.-------ebrietatis.-------of drunkennefs. 4. Somnium. Dreams. 5. Hallucinatio vifus. Deception of fight. 6. - auditus. ---------of hearing. 7. Rubor a calore. Blufh from heat. 8. —— jucunditalis. -----from joy. 9. Priapifmus amatorius. Amorous priapifm. 10. Difientio mamularum. Distention of the nipples. ORDO Class II. 2. 2.] OF SENSATION. 21? ORDO II. Decreafed Senfation, GENUS I. With Decreafed Afftion of the general Syfiem. SPECIES. 1. Stultitia infenfibilis. Folly from infenfibility. 2. Tadium vita. Irkfomenefs of life. 3. Pare/is fenfitiva. Senfitive debility. GENUS II. With decreafed Aclions of particular Organs. SPECIES. I. Anorexia. Want of appetite. 2. Adipfia. Want of thirft. 3. Impotentia* Impotence. 4. Sterilitas. Barrennefs. 5. Infenfibilitas artuum. Infenfibility of the limbs. 6. Dyfuria infenfitiva. Infenfibility of the bladder. 7. Accumulatio alvina* Accumulation of feces. ORDO r* DISEASES [Class II. 3.1. t ORDO III. Retrograde Senfitive Motions. GENUS I. Of Excretory Duels. SPECIES. Motus retrogreffus. Retrograde motion. 1.------ureterum. ----------of the ureters, 2.----- urethra. ----------of the urethra. 3.------ duclus choledoci*---------- of the bile-duCt. CLASS Class II. i. i.] OF SENSATION. 2TC CLASS II. DISEASES OF SENSATION. ORDO I. Increafed Senfation. GENUS I. With increafed Aclion of the Mufcles. The aCtions belonging to this genus are thofe which are immediately excited by the fenfations of pain or pleafure, but which are neither followed by inflamma- tion, nor by convulfion. The former of which be- long to the fubfequent genera of this order, and the latter to the clafs of voluntary motions. The criterion between the actions, which are the immediate confequence of painful fenfation, and con- vulfive actions properly fo called, confifts in the former having a tendency to diflodge the ftimulating caufe, which induces the painful fenfation; and the latter being exerted for the purpofe of expending the fenfo- rial power, and thus dulling or destroying the general fenfation of the fyftem. See Clafs III. i. There is a degree of heat produced in the affected part by thefe fenfitive actions without inflammation, but in much lefs quantity than when attended by in- flammation ; as in the latter there is a production of new veffels. See Sect. XXXIII. 2. 3, Some s^o DISEASES [Class II. i. i. Some of the fpecies of this genus cannot properly be termed difeafes in their natural ftate, but become fo by their defect or excefs, and are here inferted to facilitate the explanation of the others. SPECIES. i. Deglutitio* Swallowing our food is immediately caufed by the pleafurable fenfation occafioned by its ftimulus on the palate or fauces, and is acquired long before the nativity of the animal. Afterwards the pain of hunger previoufly produces the various volun- tary exertions to procure the proper material, but the actions of mafticating and of fwallowing it are effected by the fenforial power of fenfation ; which appears by their not being always controlable by the will, as when children in vain attempt to fwallow naufeous drugs. See Clafs IV. i. 3. 1. The mafticated food Stimulates the palate, which is an organ of fenfe, into fo much action, as to produce agreeable fenfation ; and the mufcles fubfervient to deglutition are brought into action by the fenfation thus produced. The pleafurable fenfation is the proximate caufe; the aCtion of the fibres of the extremities of the nerves of tafte is the remote caufe ; the fenforial power of irrita- tion exciting thefe fibres of the nerves of tafte into in- creafed action is the pre-remote caufe; the action of the mufcles of deglutition is the proximate effeCt; the pufhing the food into the ftomach is the remote effect; and the nutrition of the body is the poll-remote effect. Though Class II. i. i.] OF SENSATION 221 Though the mufcles fubfervient to deglutition have their actions previoufly affociated, fo as to be excited into fynchronous tribes or fucceffive trains, either by volition, as when we fwallow a difagreeable drug ; or by fenfation, as when we fwallow agreeable food ; or by irritation, as when we inattentively fwallow our faliva ; yet do all thofe three kinds of deglutition be- long to the refpeCtive claffes of volition, fenfation, and irritation ; becaufe the firft links of thefe tribes or trains of mufcular action are excited by thofe fenforial powers, and the affociated links, which accompany or fucceed them, are excited by the combined powers either of volition, or of fenfation, or of irritation, along with that of affociation. 2. Refpiratio. Refpiration is immediately caufed by the fenforial power of fenfation in confequence of the baneful want of vital air; and not from the accu- mulation of blood in the lungs, as that might be car- ried on by inhaling azote alone, without the oxyge- nous part of the atmofphere. The action of refpira- tion is thus fimilar to that of fwallowing our food to appeafe the pain of hunger ; but the lungs being fur- rounded with air, their proper pabulum, no interme- diate voluntary exertions are required, as in hunger, to obtain and prepare the wanted material. Refpiration is fimilar to flow combuftion ; the ox- ygenous part of the atmofphere is received through the moift membranes, which line the air-cells of the lungs, and uniting with the inflammable part of the blood generates an acid, probably the phofphoric acid 22i DISEASES [Class II. i. r. acid ; a portion of carbonic acid is likewife produced in this procefs; as appears by repeatedly breathing over lime-water, which then becomes turbid. See Botanic Garden, P. I. Canto I. 1. 401. note. 3. Sternutatio* Sneezing confifts of mufcular actions produced by the fenforial faculty of fenfation ; and is an effort to diflodge, by means of air forcibly impelled through the noftrils, fome material; which ftimulates the membrane, which lines them, into too great action, and might thence injure the fenfe of fmell which is diffufed on it. In this operation the too great action of the veffels of the membrane of the noftrils is the remote caufe ; the fenfation thence induced is the proximate caufe ; and the mufcular actions are the proximate effect. This aCtion of fneezing frequently precedes common refpiration in new-born children, but I believe not always ; as like the latter it cannot have been previ- oufly acquired in the uterus. It is produced in fome people by fudden light, as by looking up at the Sky in a morning, when they come out of a gloomy bed-chamber. It then becomes anaffociate action, and belongs to Clafs IV. 1. 2. 2. M. M. When it is exerted to excefs it may be cured by Snuffing Starch up the noftrils. See Clafs I. 1. 2. 13. 4. Anhelitus. Panting. The quick and laborious breathing of running people, who arc not accuftomed to violent exercifc, is occafioned by the too great con- flux Class II. i. i.] OF SENSATION. 2*j flux of blood to the lungs. As the fanguiferous fyf. tern, as well as the abforbent fyftem, is furniflied in many parts of its courfe with valves, which in general prevent the retrograde movement of their contained fluids; and as all thefe veffels, in fome part of their courfe, lie in contact with the mufcles, which are brought into aCtion in running, it follows that the blood muft be accelerated by the intermitted fwelling of the bellies of the mufcles moving over them. The difficulty of breathing, with which'very fat people are immediately affected on exercife, is owing to the preffure of the accumulated fat on the veins, arteries, and lymphatics; and which, by diftending the ikin, occafions it to act as a tight bandage on the whole furface of the body. Hence when the mufcles are excited into quicker action, the progrefs of the blood in the verrir, and of the lymph and chyle in the abforbent fyftem, is urged on with much greater force, as under an artificial bandage on a limb, explained in Art. IV. 2. 10. and in Sect. XXXIII. 3. 2. Hence the circulation is inftantly quickened to a great degree, and the difficulty of breathing is the confequence of a more rapid circulation through the lungs. The in- creafed fecretion of the perfpirable matter is another confequence of this rapid circulation; fat people, when at reft, are believed to perfpire lefs. than others, which may be gathered from their generally having more liquid ftools, more and paler urine, and to their fre- quently taking lefs food than many thin people ; and laftiy, from the perfpiration of fat people being gene-* rally "4 DISEASES [Class II. 1.1. rally more inodorous than that of lean ones; but when corpulent people are put in motion, the fweat Stands in drops on their Skins, and they " lard the ground" as they run. The increafe of heat of cor- pulent people on exercife, is another confequence of their more rapid circulation, and greater fecretion. See Clafs I. 2. 3. 17. Other caufes of difficult or quick refpiration will be treated of under Afthma, Pertuifis, Peripneumony, Tonfillitis. 5. Tuffis ebriorum. Senfitive cough is an exertion of the mufcles ufed in expiration excited into more violent aCtion by the fenforial power of fenfation, in confequence of fomething which too powerfully ftimu- lates the lungs. As the faline part of the fecreted mucus, when the abforption of it is impeded ; or the too great vifcidity of. it, when the abforption is in- creafed ; or the too great quantity of the mucus, when the fecretion is increafed; or the inflammation of the membranes of the lungs; it is an effort to diflodge any of thefe extraneous materials. Of this kind is the cough which attends free- drinkers after a debauch ; it confifts of many fhort ef- forts to cough, with a frequent expuition of half a tea-fpoonful of frothy mucus, and is attended with confiderable thirft. The thirft is occafioned by the previous diffipation of the aqueous parts of the blood by fenfible or infenfible perfpiration; which was pro- duced by the increafed action of the cutaneous and 4 pulmonarv Class II. i. i.] OF SENSATION. 225 pulmonary capillaries during the ftimulus of the wine. In confequence of this an increafed abforption com- mences to replace this moifture, and the ikin and mouth become dry, and the pulmonary mucus be- comes infpiffated ; which ftimulates the bronchia, and is raifed into froth by the fucceffive currents of air in evacuating it. This production of froth is called by fome free-drinkers " fpitting fixpences" after a de- bauch. This fubfequent thirft, dry mouth, and vifcid expectoration in fome people fucceeds the flighteft de- gree of intoxication, of which it may be efteemed a criterion. See Clafs IV. 2. 1.8. As coughs are not always attended with pain, the mufcular aCtions, which produce them, are fometimes excited by the fenforial faculty of irritation, as in Clafs I. 1. 2. 8. I. 1. 3. 4. I. 1. 4. 3. I. 2. 3. 4. Coughs are alfo fometimes convulsive, as in Clafs III. 1. 1. 10. and fometimes fympathetic, as Clafs IV. 2. 1. 7. M. M. Venefection, when the cough is attended with inflammation. Mucilages. Opium. Torpentia. Blifter. 6. Singultus. Hiccough is an exertion of the muf- cles ufed in infpiration excited into more violent aCtion by the fenforial power of fenfation, in confequence of fomething which too powerfully ftimulates the cardia ventricufi, or upper orifice of the ftomach. As when folid food is too haftily taken without fufficient dilu- tion. And is an effort to diflodge that offenfive material, and pufh it to fome lefs fenfible part of Q^ the **° DISEASES [Class II. i. ». the ftomach, or into the middle of the contained aliment. At the end of fatal fevers it may arife from the acrimony of the undigested aliment, or from a part of the ftomach being already dead, and by its weight or coldnefs affecting the furviving part with difagreeable fenfation. The pain about the upper orifice of the ftomach is the proximate caufe, the too great or too little action of the fibres of this part of the ftomach is the remote caufe, the action of the mufcles ufed in infpiration is the proximate effect, and the repercuffion of the offending material is the remote effeCt. Hiccough is fometimes fympathetic, occafioned by the pain of gravel in the kidney or ureter, as in Clafs IV. i. i. 7. and is fometimes a fymptom of epilepfy or reverie, as in Sect. XIX. 2. M. M. Oil of cinnamon from one drop gradually increafed to ten, on fugar, or on chalk. Opium. Blifter. Emetic. 7. Afthma humor ale. The humoral afthma pro- bably confifts in a temporary anafarca of the lungs, which may be owing to a temporary defect of lym- phatic abforption. Its caufe is nevertheless at prefent very obfcure, fince a temporary deficiency of venous abforption, at the extremities of the pulmonary or bronchial veins, might occafion a fimilar difficulty of refpiration. See Abortio, Clafs I. 2. 1. 14. Or it might be fuppofed, that the lymph effufed into the cavity of the cheft might, by fome additional heat during Class II. r. i.] OF SENSATION. 227 during fleep, acquire an aerial form, and thus comprefs the lungs; and on this circumftance the relief, which thefe patients receive from cold air, would be readily accounted for. The paroxyfms attack the patient in his firft fleep, when the circulation through the lungs in weak peo- ple wants the affiftance of the voluntary power. Clafs I. 2. 1. 3. And hence the abforbents of the lungs are lefs able to fulfil the whole of their duty. And part of the thin mucus, which is fecreted into the air- cells, remains there unabforbed, and occafions the dif- ficult refpiration, which awakes the patient. And the violent exertions of the mufcles of refpiration, which fucceed, are excited by the pain of fuffocation, for the purpofe of pufliing forwards the blood through the compreffed capillaries, and to promote the abforption of the effufed lymph. In this the humoral differs from the convulfive afthma, treated of in Clafs III. 1. 1. 10. as in that there is probably no accumulated fluid to be abforbed; and the violent refpiration is only an exertion for the purpofe of relieving pain, either in the lungs or in fome diftant part, as in other convulfions, or epilepfy ; and in this refpect the fits of humoral and convulfive afthma effentially differ from each other, contrary to the opinion expreffed without fufficient consideration in Sea. XVIII. 15. The patients in the paroxyfms both of humoral and convulfive afthma find relief from cold air, as they ge- nerally rife out of bed, and open the window, and Q^2 put 225 DISEASES [Class II. i. f. put out their heads ; for the lungs are not fenfible to cold, and the fenfe of fuffocation is fomewhat relieved by there being more oxygen contained in a given quantity of cold frefli air, than In the warm confined air of a clofe bed-chamber. I have feen humoral afthma terminate in confirmed anafarca, and deftroy the patient, who had been an exceflive drinker of fpirituous potation. And M. Sa- vage afferts, that this difeafe frequently terminates in diabetes ; which feems to Shew, that it is a temporary dropfy relieved by a great flow of urine. Add to this, that thefe paroxyfms of the afthma are themfelves re- lieved by profufe fweats of the upper parts of the body, as explained in Clafs I. 3. 2. 8. which would countenance the idea of their being occafioned by con- gestions of lymph in the lungs. The congestion of lymph in the lungs from the de- fective abforption of it is probably the remote caufe of humoral afthma ; but the pain of fuffocation is the immediate caufe of the violent exertions in the pa- roxyfms. And whether this congestion of lymph in the air-cells of the lungs increafes during our fleep, as above fuggefted, or not; the pain of fuffocation will be more and more diftreffing after fome hours of fleep, as the fenfibility to internal ftimuli increafes during that time, as defcribed in Sect. XVIII. 15. For the fame reafon many epileptic fits, and paroxyfms of the gout, occur during fleep. In two gouty cafes, complicated with jaundice, and pain, and ficknefs-, the patients had each of them a fhivering Class II. i. i.J OF SENSATION. 22g fliivering fit, like the commencement of an ague, to the great alarm of their friends ; both which com- menced in the night, I fuppofe during their fleep ; and the confequence was a ceffation of the jaundice, and pain about the Stomach, and ficknefs; and inftead of that the gout appeared in their extremities. In thefe cafes I conjecture, that there was a metaftafis not only of the difeafed aCtion from the membranes of the liver to thofe of the foot; but that fome of the new veffels, or new fluids, which were previoufly produced in the inflamed liver, were translated to the feet during the cold Sit, by the increafed abforption of the hepatic lymphatics, and by the retrograde motions of thofe of the affected limbs. This I think refembles in fome refpeCts a fit of hu- moral afthma, where ftronger motions of the abfor- bent veffels of the lungs are excited, and retrograde ones of the correfpondent cutaneous lymphatics; whence the violent fweats of the upper parts of the body only are produced; and for a time the patient becomes relieved by the metaftafis and elimination of the offending material by fenfitive exertion. For a further account of this intricate Subject fee Clafs 111. I. I. 10. M. M. To relieve the paroxyfm a tea-fpoonful of ether may be given mixed with water, with 10 drops of laudanum, to be repeated three or four times,. Venefection. An emetic. A blifter. Afterwards the Peruvian bark, with a grain of opium at night, and two or three of aloes. A flannel fliirt in winter, but not in fummer. Iffues. Digitalis ? 23» DISEASES [Class II. i. r. In this fpecies of afthma, there is great reafon to believe, that the refpiration of an atmofphere, with an increafed proportion of oxygen, will prove of great advantage ; fome well-obferved and well-attefted cafes of which are published by Dr. Beddoes; as this purer air invigorates the circulation, and the whole fyftem in confequence, perhaps not only by its ftimulus, but by its fupplying the material from which the fenforial power is extracted or fabricated. In fpafmodic afthma, on the contrary, Dr. Ferriar has found undoubted benefit from an atmofphere mixed with hydrogen. See Seft. XVIII. 15. and Clafs III. 1. 1. 10. 8. Niclitatiofenfitiva. Winking of the eyes is per- formed every minute, without our attention, for the purpofe of diffufing the tears over them, which are poured into the eye a little above the external corner of it, and which are afterwards abforbed by the lacrymal points above and below the internal corner of it. When this operation is performed without our attention, it is caufed by the faculty of irritation, and belongs to Clafs I. 1. 4. 1. but when it is produced by a ftronger ftimulus of any extraneous material in the eye, fo as to caufe pain, the violent and frequent niaitation is caufed by the faculty of fenfation. This difeafe is fometimes produced by the introver- sion of the edge of the lower eyelid, which bends the points of the hairs of the eyelafh ^upon the ball of the eye, which perpetually Stimulate it into painful fen- fation. This introverfion of the eyelid is generally owing to a tumor of the cellular membrane below the Class II. i. i.] OF SENSATION. 231 edge of the eyelid, and though a very tronblefome complaint may often be cured by the following fimple means. A little common plafter fpread on thin linen, about a quarter of an inch long, muft be rolled up fo as to be about the fize of a crow-quill, this muft be applied immediately below the eyelafli on the outfide of the eye ; and muft be kept on by another plafter over it. This will then aa as a flight compreffion on the tumor under the eyelafli, and will prevent the hairs from touching the eye-ball. In a week or two the compreffion will diminish the tumor it lies over, and cure this painful deformity. 9. Ofcitatio et pandiculatio. Yawning and ftretching -of the limbs is produced either by a long inaaivity of the mufcles now brought into aaion, as fometimes happens after Sleep, or after listening a long time to a dull narrative; ©r it Is produced by a too long con- tinued aaion of the antagonist mufcles. In the former cafe there is an accumulation of fenforial power during" the quiefcence of the mufcles now brought into aaion ; which probably constitutes the pain or wearifomenefs of a continued attitnde. In the latter cafe there is an exhauftion of fenforial power in the mufcles, which have lately been aaing violently, and a confequent accumulation in the mufcles, which are antagonists to them, and which were at reft. Thefe involuntary motions are often feen in para- lytic limbs, which are at the fame time completely dif- obcdient to the will; and are frequently obfervable in 0^4 ver}- 23* DISEASES [Class II. i. i. very young children; and from thence we may con- dude, that thefe motions are learnt before nativity; as puppies are feen to open their mouths before the mem- branes are broken. See Sea. XVI. 2. Where thefe motions are obferved in limbs other- wife paralytic, it is an indication that elearic Shocks may be employed with advantage, as the excitability of the limb by irritation is not extina, though it be difobedient both to volition and fenfation. 10. Tenefmus confifts in violent and frequent in- effeaual efforts to difcharge the contents of the rec- tum, owing to pain of the fphinaer. The pain is produced by indurated feces, or by fome acrid mate- rial, as the acidity of indigested aliment; and the ef- forts are attended with mucus from the pained mem- brane. The feces muft fometimes be taken away by the end of a marrow-fpoon, as cathartics and even clyfter will pafs without removing them. It is fome- times caufed by fympathy with the urethra, when there is a ftone at the neck of the bladder. See Clafs II. 2. 2. 7. and IV. 1. 2. 8. M. M. Fomentation, an enema with mucilage and laudanum. The common exclufion of the feces from the reCtum is a procefs fimilar to this, except that the mufcles of the fphinaer ani, and thofe of the abdomen, which act along with them by the combined powers of fen- fation and affociation, are in tenefmus excited by pain- ful fenfation, and in the latter by a fenfation, which may Class II. i. i.] OF SENSATION. 23J may in fome inftances be almoft called pleafurable, as relieving us from a painful one in the exclufion of the feces. 11. Stranguria. Strangury confifts in painful ef- forts to difcharge the contents of the urinary bladder. It is generally owing to a ftone in the fphinaer of the bladder ; or to the inflammation of the neck of it oc- cafioned by cantharides. It is fometimes caufed by fympathy with the piles; and then is liable in women to occafion convulfions, from the violence of the pain without inflammation. See Clafs IV. 2. 2. 2. and 3. M. M. Fomentation, clyfter with oil and lauda- num, pufli the ftone back with a bougie ; if from cantharides give half a pint of warm water every ten minutes. Mucilage of gum arabic and traga- canth. The natural evacuation of the urine is a procefs fimilar to this, except that the mufcular fibres of the bladder, and the mufcles of the abdomen, which aa in concert with them by the combined powers of fen- fation and of affociation, are, in the former cafe of ftrangury, excited into aaion by painful fenfation; and in the latter by a fenfation, which may almoft be termed pleafurable, as it relieves us from a pre- vious uneafy one. The ejeaio feminis is another procefs in fome re- fpeCts fimilar to ftrangury, as belonging to the fame fenfible canal of the urethra, and by exciting into aaion the accelerator mufcles; but in the ftrangury thefe 234 DISEASES [Class II. i. i. thefe mufcles are excited into aaion by painful fen- fation, and in the ejeaion of the femen by pleafurable fenfation. 12. Parturitio. Parturition is not a difeafe, it is a natural procefs, but is more frequently unfortunate in high life than amongft the middle clafs of females; which may be owing partly to fear, with which the priefts of Luc in a are liable to infpire the ladies of fafhion to induce them 10 lie in in town ; and partly to the bad air of London, to which they purpofely refort. There are however other caufes, which render parturition more dangerous to the ladies of high life; fuch as their greater general debility from neglea of energetic exercife, their inexperience of the variations of cold and heat, and their feclufion from freSh air. To which muft be added, that great Source of the deftruaion of female grace and beauty, as well as of female health, the tight ftays^ and other bandages, with which they are generally tortured in their early years by the aaive folly of their friends, which by difplacing many of the vifcera impedes their aaions, and by comprefling them together produces adhefions of one part to another, and affects even the form and aperture of the bones of the pelvis, through which the nafcent child muft be protruded. As parturition is a natural, not a morbid procefs, no medicine fhould be given, where there is no ap- pearance of difeafe. The abfurd cuftom of giving a powerful Class II. i. i.] OF SENSATION. 235 powerful opiate without indication to all women, as foon as they are delivered, is, I make no doubt, fre- quently attended with injurious, and fometimes with fatal confequences. See Clafs II. 1. 2. 16. Another thing very injurious to the child, is the tying and cutting the navel-ftring too foon ; which fhould always be left till the child has not only repeat- edly breathed, but till all pulfation in the cord ceafes. As otherwife the child is much weaker than it ought to be ; a part of the blood being left in the placenta, which ought to have been in the child; and at the fame time the placenta does not fo naturally collapfe, and withdraw itfelf from the fides of the uterus, and is not therefore removed with fo much fafety and cer- tainty. The folly of giving rue or rhubarb to new- born children, and the danger of feeding them with gruel inftead of milk, is fpoken of in Clafs I. 1. 2. 5. and II. 1. 2. 16. ORDO 236 DISEASES [Class II. i. j. ORDO I. Increafed Senfation. GENUS II. With the Produclion of new Veffels by internal Membranes or Glands, with Fever. In the firft clafs of difeafes two kinds of fevers were flefcribed, one from excefs, and the other from defea of irritation ; and were in confequence termed irri- tative, and inirritative fevers. In this fecond clafs of difeafes another kind of fever occurs, which is caufed by excefs of fenfation, and termed in confequence Sen- fitive Fever. But there is no fever from defea of fenfation, becaufe the circulation is carried on in health without our confeioufnefs, that is, without any fen- iation attending it. But as excefs of fenfation may exift with excefs or defea of irritation, two other kinds of fever arife from a combination of fenfitive fever with the irrita- tive, and inirritative ones. Making five kinds in all. i. Irritative fever, defcribed in Clafs I. i. i. i. 2. Inirritative fever. Clafs I. 2. 1. 1. 3. Senfitive fever. Clafs II. 1. 6. 1. 4. Senfitive irritated fever. Clafs II. 1. 2. 1. 5, Senfitive inirritated fever. Clafs II. 1.3. 1. As the fenfitive irritated fever attends all the dif- eafes enumerated under the genus about to be de- fcribed. Class II. i. 2.] OF SENSATION. 237 fcribed, it is placed at the head of it. And as the fenfitive inirritated fever accompanies the greateft number of the fpecies enumerated under the third genus of this order, it is placed at the head of them. And as the fenfitive fever attends the difeafes of the fixth genus, it is placed at the head of them. But as every febrile paroxyfm confifts of difordered tribes or trains of affociated motions, it may be doubted, whe- ther they ought not all to have been placed in the fourth clafs, amongft the difeafes of affociation. See Clafs IV. 2. a. 11. All the fubfequent fpecies of this genus are attended with fenfitive irritated fever; there are neverthelefs fome fuperficial inflammations, which affea the fame fituations without much fever, as the fcrophulous oph- thalmy and fpurious peripneumony, which belong to- other genera. Inflammation is uniformly attended with the pro- duaion or fecretion of new fibres conftituting new veffels; this therefore may be efteemed its effential charaaer, or the criterion of its existence. The ex- tenfion of the old veffels feems rather a confequence than a caufe of the germination, or pullulation, of thefe new ones ; for the old veffels may be enlarged, and excited with unufual energy, without any pro- duaion of new ones, as in the blufli of Shame or of anger. When thefe new veffels are formed, if they are not reabforbed into the circulation, they fecrete a new fluid called purulent matter ; which generally opens itfelf «3* DISEASES [Class II. i. 2. itfelf a paffage on the external ikin, and produces an ulcer, which either gradually heals, or fpreads, and is the caufe of heaic fever ; or they fecrete contagious matter, which has the property of exciting the fame kind of inflammation, and of producing the fame kind of contagious matter, when inferted by inoculation into the ikin of other perfons. Thefe contagious matters form ulcers, which either heal fpontaneoufly, or by art ; or continue to fpread, and deftroy the pa- tient, by other kinds of heaic fever. In this genus there is an increafe of the fenforial power of irritation as well as of fenfation; whence great arterial energy is produced, and the pulfe be- comes ftrong and full, as well as quick ; and the coats of the arteries feel hard under the finger, being them- felves thickened and diftended by inflammation. . The blood drawn, efpecially at the fecond bleeding, is covered with a tough fize ; which is probably the mu- cus from the inflamed internal furface of the arteries, increafed in quantity, and more coagulable than in its natural ftate; the thinner part being more perfeaiy abforbed by the increafed aaion of the inflamed ab- forbents. See Sea. XXXIII. 2. 2. This is rendered more probable, becaufe the hard feel of the pulfe, and the abundance of coagulable lymph commence, exift, and ceafe together. Great heat is produced from the new chemical combinations arifing in the fecretion of new fibres, and great pain from the diftention of old ones, or from their increafed aCtion. The increafed quantity of Class II. i. 2.] OF SENSATION. 3-39 of fenfation from a topical inflammation or phlegmon is the immediate caufe of the febris fenfitiva irritata, or inflammatory fever ; as when it arifes from the pain of pleurify, or paronychia ; but generally an ir- ritative fever precedes this topical inflammation, which occurs during the hot fit of it; and then the irritative fever is changed into a fenfitive irritated fever, by the additional caufe of the fenforial power of fenfation befidesthat of irritation. SPECIES. 1. Febris fenfitiva irritata. Senfitive irritated fever, or inflammatory fever. Phlegmasia. A ftrong full pulfe, with inflammation of the coats of the arteries, constitutes this difeafe. It originates from fome to- pical inflammation, which, if the fever is not fub- dued, terminates in fuppuration; and differ-; from irritative fever in refpea to the painful fenSation which accompanies it. For as pleafurable fenfation is the caufe of the growth of the new veffels, and dif- tention of the old ones, in the natural enlargement of the body during our infancy ; fo a painful fenfation is the caufe of the unnatural produaion of new veffels, and enlargement of old ones in inflammatory dif- eafes. When matter is thus formed in any internal vifcus, or in the cellular membrane, as in the lungs or liver ; fo long as this abfcefs remains without admiflion of air, this inflammatory fever is liable to continue, receiving only temporary relief by bleeding or emedcs, or ca- thartics ; 24* DISEASES [Class II. i. 2. thartics; till the patient, after a month, or two, or three, expires. But, if air be admitted to thefe in- ternal abfceffes, this kind of fever is changed into a heaic fever in a fingle day. It alfo fometimes hap- pens, that when the abfcefs remains unopened to the air, if the matter has become putrid, that heaic fever Supervenes, with colliquative fweats, or diarrhcea; the matter in both cafes is fometimes abforbed, and the fides of the abfcefs grow together again without an external aperture. See Clafs II. i. 4. i. and 2. Another termination of inflammation is in gangrene, but this belongs to the inflammation of the external ikin ; as the produaion of purulent matter belongs to inflammation of the internal or mucous membranes* Thus when the external Skin is the feat of inflamma- tion, as in erythema, or eryfipelas, and produces fen. fitive irritated fever, no collection of purulent matter can be formed; but a material oozes out, and lies upon the furface, like that in the confluent fmall-pox, and the cuticle at length peels off, or gangrene Super- venes. It muft be noted, that thefe kinds of inflam- mation can exift together ; and fome parts of the cel- lular membrane may fuppurate at the fame time that the external ikin is affeaed with erythema, or ery- fipelas. M. M. Venefeaion. Cathartics, diluents. Cool air. Torpentia. Cold Bath ? See Sea. XII. 6. The increafed arterial aaion in this fenfitive irritated fever is not fimply owing to the increafed irritability of the arterial fyftem, or to the ftimulus of the diften- 4 tion Class II. i. 2 ] OF SENSATION. 24I tion of the veffels, but alfo to the increafed acrimony or pungency of the blood ; which has now fo far changed its nature as to become more fluid, more denfe, and to be loaded with coagulable lymph. Hence it becomes neceffary not only to leffen the quantity of blood by venefeaion and by cathartics, but alfo to dilute its acrimony, or pungency, by the introduaion of aqueous and mucilaginous fluids, fuch as barley water, cream and water, fugar and water, weak broths; to which may be added fo much of fome ve- getable effential oil, as may render them grateful to the ftomach, and thus promote their abforption, as by infufing parlley or cellery and turnips in the broth ; or by balm, mint, or fage teas. The following fpecies of this genus only distinguish the fituation of the part previoufly inflamed, and which is the remote caufe of the fenfitive irritated, or inflammatory fever, which attends it. 2. Opthalmia interna. Inflammation of the eye is attended with the produaion of new veffels, which fpread over the tunica adjunaiva, and over the cor- nea ; thefe new veffels are eafily feen, as they lie on a white ground, and give ocular demonstration of their produaion in inflammation. When this inflammation of the cornea fuppurates, it is liable to leave little ulcers, which may be feen beneath the furface in the form of little excavations; and as thefe heal, they are liable to be covered with an opake fear. This fear, ja fom« months or years, is liable to wear away, and R. become 242 DISEASES [Class II. 1.1. become tranfparent, without the affiftance of any po- lifliing powder, as of very finely levigated glafs, as- fome have recommended. But when the cornea is affeaed through all its thicknefs, the return of its tranfparency becomes hopelefs. See Clafs I. i. 3. 14. In violent degrees of opthalmy the internal parts, as the retina, optic artery, iris, ciliary procefs, become inflamed, as well as the external ones; hence the leaft light admitted to the eye occafions intolerable pain. This curious circumftance cannot be owing to the aaion of light on the inflamed veffels of the cornea ; it therefore Shew*, that the extremity of the optic nerve or retina is alfo rendered more exquisitely fen- fible to light, by partaking of the inflammation; and I have been told, that red colours are in thefe cafes fometimes painfully perceived even in perfea dark- nefs. This Shews that the retina is excited into mo- tion by the ftimulus of light; and that, when it is in- flamed, thefe motions give great pain, like thofe of other inflamed parts, as the mufcles, or membranes. And; fecondly, that the ideas of colours confift in the motions of the retina; which ideas occafion pain, when the extremity of the moving nerve is inflamed. M. M. Venefeaion. Cathartics.' Diluents. Tor- pentia. Frequently moiften the eye with cold water by means of a rag. Cool airy room. Darknefs. When the inflammation begins to decline, white vi- triol gr. vi. in an ounce of water is more efficacious to moiften the eye than folutions of lead. Tinaure of opium diluted. New veffels from the inflamed tunica Class If. i. O ^F SENSATION. 243 tunica adnata frequently fpread like a fly's wing upon the tranfparent cornea, which is then called Pterigium. To Stop the growth of this, the principal veflels Should be cut through with a lancet. When the iiiilamma- tion begins to decline, after due evacuation any ftimu- lating material put into the eye increafes the abforp- tion, which foon removes the new red veffels ; which has given rife to a hundred famous eye-waters, and eye-doaors; if thefe ftimulating materials are ufed too foon, the inflammation is increafed by them. See Sea. XXXII. 2. 10. There is another opthalmia, which attends weak children, and is generally efteemed a .Symptom of fcrophula, as defcribed in Clafs II. 1. 5. 3. and ano- ther, which is of venereal origin, mentioned in Clafs II. 1. 5. 2. both which may be termed opthalmia fu- perficialis. 3. Phrenitis. Inflammation of the brain is attended with intolerance of light and found ; which Shews, that the extremities of the nerves of thofe fenfes are at the f; me time inflamed ; it is alfo attended with great pain of the head, with watchfulnefs, and furious delirium. The violent efforts, thefe patients are Said fometimes to exert, are owing to the increafed fecre- tion of fenforial power in the brain; as all other in- flamed glands have a greater circulation of blood paf- fing through them, and a greater fecretion in confe- quence of their peculiar fluids, as in the hepatitis much more bile is generated. R 2 M. M. Vene- S44 DISEASES [Class II. i. a. M. M. Venefeaion. Cathartics. Torpentia. Fo- ment the head with cold water for hours together. Or with warm water. Cool airy room. Afterwards cupping on the occiput. Leeches to the temples. When the patient is weakened a blifter on the head, and after further exhauftion five or fix drops of tinc- ture of opium. 4. Peripneumonia. Inflammation of the lungs. The pulfe is not always hard, fometimes foft ; which is probably owing to a degree of ficknefs or inaaion of fhe ftomach ; with dull pain of the cheft ; refpiration; constantly difficult, fometimes with erea pofture ; the face bloated and ptirplifh ; cough generally with moift txpeaoraticn, often Stained with blood. When Jie difficulty of refpiration is very great, the patient is not able to cough ; in this fituation, after copious bleeding, the cough is liable to return, and is fo far a favourable fymptom, as it Shews fome abate- ment of the inflammation. A peripneumony frequency occurs in the chin- cough, and deftroys the patient, except immediate recourle be had to the lancet, or to four or five leeches ; when blood cannot be otherwife taken. The peripneumony is very fatal to young children, f Specially as I believe it is frequently mistaken for a fpafmodic afthma, or for the croup, or cynanche tra- rheaiis of Cullen. Beth which, however,, when they occur, require immediate venefeaion by the eh. Towards the end of the difeafe fmall dofes of opium before the evening paroxyfms, and laftly the Peruvian bark, and chalybeate wine, at firft in fmall dofes, as 20 drops twice a day, and afterwards, if neceffary, in larger. See Art. IV, 2. 6. Mrs. Ciass II. i. 2.] OF SENSATION. i53 Mrs. C. a lady in the laft month of her pregnancy, was feized with violent hepatitis, with fymptoms both of peripneumony and of pleurify, for it feldom hap- pens in violent inflammations, that one vifcus alone is affeaed ; She wanted then about a fortnight of her delivery, and after frequent venefeaion, with gentle cathartics, with fomentation or warm bath, She reco- vered and was fafely delivered, and both herfelf and child did well. Rheumatic and eruptive fevers are more liable to induce abortion. 13. Splenitis. Inflammation of the fpleen commences with tenfion, heat, and tumour of the left fide, and with pain, which is increafed by preffure. A cafe is defcribed in Clafs I. 2. 3. 18. where a tumid fpleen, attended with fever, terminated in fchirrus of that vifcus. 14. Nephritis. Inflammation of the kidney feems to be of two kinds; each of them attended with dif- ferent fymptoms, and different modes of termination. One of them I fuppofe to be an inflammation of the external membrane of the kidney, ariling from gene- ral caufes of inflammation, and accompanied with pain in the loins without vomiting ; and the other to confift in an inflammation of the interior parts of the kidney, occafioned by the ftimulus of gravel in the pelvis of it, which is attended with perpetual vomiting, with pain along the courfe of the ureter, and retraaion of the teftis on that fide, or numbnefs of the thigh. The »5<5 DISEASES [Class I. i. t. The former of thefe kinds of nephritis is diftin- guifhed from lumbago by its fituation being more ex- aaiy on the region of the kidney, and by its not be- ing extended beyond that part; after three or four days I believe this inflammation is liable to change place ; and that a herpes or eryfipelas, called zona, or fhingles, breaks out about the loins in its Stead ; at other times it is cured by a cathartic with calo- mel, with or without previous venefeaion. The other kind of nephritis, or inflammation of the interior part of the kidney, generally arifes from the pain occafioned by the ftimulus of a ftone enter?- ing the ureter from the pelvis of the kidney ; and which ceafes when the ftone is protruded forwards into the bladder ; or when it is returned into the pelvis of the kidney by the retrograde aaion of the ureter. The kidney is neverthelefs inflamed more fre- quently, though in a lefs degree, from other caufes ; efpecially from the intemperate ingurgitation of ale, or other fermented or fpirituous liquors. This lefs degree of inflammation is the caufe of gravel, as that before mentioned is the effea of it. The mucus fe- creted to lubricate the internal furface of the urinife- rous tubes of the kidney becomes fecreted in greater quantity, when thefe veffels are inflamed; and, as the correfpondent abforbent veffels aa more energe- tically at the fame time, the abforption of its more fluid parts is more powerfully affeaed; on both thefe accounts the mucus becomes both changed in qua- lity and more indurated. And in this manner ftones i are Class II. i. 2.] OF SENSATION. 2J7 are produced on almoft every mucous membrane of the body; as in the lungs, bowels, and even in the pericardium, as fome writers have affirmed. Sec Clafs I. 1. 3. 9. M. M. Venefeaion. Ten grains of calomel given in fmall pills. Then infufion of fenna with oil. Warm bath. Then opium a grain and half. See Clafs I. 1. 3. 9. for a further account of the method of cure. 15. Cyfkitis. Inflammation of the bladder is at- tended with tumor and pain of the lower part of the belly ; with difficult and painful miaurition; and te- nefmus. It generally is produced by the exiftence of a large ftone in the bladder, when in a great degree; or is produced by common caufes, when in a Slighter degree. The ftone In the bladder is generally formed in the kidney, and paffing down the ureter into the bladder becomes there gradually increafed in fize; and this moft frequently by the appofition of concentric fpheres, as may be feen by fawing fome of the harder culculi through the middle, and polifliing one furface. Thefe new concretions fuperinduced on the nucleus, which defcended from the kidney, as defcribed in Clafs I. 1. 3. 9. and in the preceding article of this genus, is not owing to the microcotmic fait, which is often feen to adhere to the fides of chamber-pots, as this is foluble in warm water, but to the mucus of the bladder, as it rolls along the internal furface of it. S Now 258 DISEASES [Class II. 1.2. Now when the bladder is Slightly inflamed, this mucus of its internal furface is fecreted in greater quantity, and is more indurated by the abforption of its more liquid part at the inftant of fecretion, as explained in Clafs I. 1.3. 9. and II. 1. 2. 14. and thus the fti- mulus and pain of a ftone in the bladder contributes to its enlargement by inflaming the interior coat of it. M. M. Venefeaion. Warm bath. Diluents. Ano- dyne clyfters. See Clafs I. 1.3. 9. 16. Hyfteritis. Inflammation of the womb is ac- companied with heat, tenfion, tumor, and pain of the lower belly. The os uteri painful to the touch. Vomiting. This difeafe is generally produced by im- proper management in the delivery of pregnant wo- men. I know an unfortunate cafe, where the pla- centa was left till the next day ; and then an unfkilful accoucheur introduced his hand, and forcibly tore it away ; the confequence was a moft violent inflamma- tory fever, with hard throbbing pulfe, great pain, very fizy blood, and the death of the patient. Some accoucheurs have had a praaice of introducing their hand into the uterus immediately after the birth of the child, to take away the placenta; which they faid was to fave time. Many women I believe have been viaims to this unnatural praaice. Others have received injury, where inflammation has been beginning, by the univerfal praaice of giv- ing a large dofe of opium immediately on delivery, without any indication of its propriety ; which, though a proper Class II. i. 2.] OF SENSATION. 259 a proper and ufeful medicine, where the patient is too feeble, when given in a fmall dofe, as 10 drops of tinaure of opium, or half a grain of folid opium, muft do a proportionate injury, when it is given im- properly ; and as delivery is a natural procefs, it is certainly more wife to give no medicines, except there be fome morbid fymptom, which requires it; and which has only been introduced into cuftom by the ill-employed aaivity of the Priefts or Priefteffes of Luc in a; like the concomitant nonfenfe of cram- ming rue or rhubarb into the mouth of the unfor- tunate young ftranger, who is thus foon made to ex- perience the evils of life. See Clafs II. 1. 1. 12. and I. 1.2. 5. Juft fo fome over-wife beldames force- young ducks and turkeys, as foon as they are hatched, to fwallow a pepper-corn. M. M. Venefeaion repeatedly ; diluents; fomen- tation ; the patient fliould be frequently raifed up in bed for a fhort time, to give opportunity of difcharge to the putrid lochia; mucilaginous clyfters. See Fe- bris Puerpera. 1 j. Lumbago fenfitiva. Senfitive Lumbago. When the extenfive membranes, or ligaments, which cover the mufcles of the back are torpid, as in the cold paroxyfm of ague, they are attended with pain ill confequence of the inaaion of the veffels, which com- pofe them. When this inaaion continues without a confequent renewal or increafe of aaivity, the difeafe becomes chronical, and forms the lumbago frigida, S 2 or 260 DISEASES [Class II. i. z. or irritativa, defcribed in Clafs I. 2. 4. 16. But when this cold fit or torpor of thefe membranes, or ligaments or mufcles of the back, is fucceeded by a hot fit, and confequent inflammation, a violent inflam- matory fever, with great pain, occurs, preventing the erea pofture of the body; and the affeaed part is liable to fuppurate, in which cafe a very dangerous ulcer is formed, and a part of one of the vertebrce is generally found carious, and the patient finks after a long time under the heaic fever occafioned by the aerated or oxygenated matter. This difeafe bears no greater analogy to rheumatifm than the inflammation of the pleura, or any other membranous inflammation; and has therefore un- juftly been arranged under that name. It is diftin- guifhed from nephritis, as it is feldom attended with vomiting, I fuppofe never, except the ureter happens to be inflamed at the fame time. The pain fometimes extends on the outfide of the thigh from the hip to the ankle, heel, or toes, and is then called fciatica ; and has been thought to confift in an inflammation of the theca, or covering of the fciatic nerve, as the pain fometimes fo exaaiy attends the principal branches of that nerve. See Clafs I. 2. 4.'15. 16. M. M. Venefeaion repeatedly ; calomel; gentle cathartics ; diluents ; warm bath ; poultice on the back, confifting of camomile flowers, turpentine, foap, and opium; a burgundy-pitch plafter. A de- bility of the inferior limbs from the torpor of the muffle?, Class II. I. 2.] OF SENSATION. 261 mufcles, which had previoufly been too much excited, frequently occurs at the end of this difeafe; in this cafe elearicity, and iffues on each fide of the lumbar vertebra?, are recommended. See Clafs I. 2. 4. 16. 18. Ifchias. The Ifchias confifts of inflammatory fever, with great pain about the pelvis, the os coc- cigis, and the heads of the .thigh bones, preventing the patient from t walking or Standing erea, with in- creafe of pain on going to ftool. This malady, as well as the preceding, has been afcribed to rheuma- tifm ; with which it feems to bear no greater analogy, than the inflammations of any other membranes. The patients are left feeble, and fometimes lame after this difeafe ; which is alfo fometimes accompanied with great flow of urine, owing to the defeaive ab- forption of its aqueous parts ; and with confequent thirft occafioned by the want of fo much fluid being returned into the circulation; a lodgment of feces in the reaum fometimes occurs after this complaint from the leffened fenfibility of it. See Clafs I. 2. 4. 15. M. M. Venefeaion ; gentle cathartics; diluents ; fomentation ; poultice with camomile flowers, turpen- tine, foap, and opium ; afterwards the bark. See Clafs L 1. 3. 5. When this inflammation terminates in fuppuration the matter generally can be felt to fluauate in the groin, or near the top of the thigh. In this circum- ftance, my friend Mr. Bent, Surgeon near Newcaftle -in Staffordshire, propofes to tap the abfcefs by means of S3 a trocar. 26z DISEASES [Class II. r. ». a trocar, and thus as often as neceffary to difcharge the matter without admitting the air. Might a weak injeaion of wine and water, as in the hydrocele, be ufed with great caution to inflame the walls of the abfcefs, and caufe them to unite? See Clafs II. i. 6. 9. 19. Paronychia interna. Inflammation beneath the finger-nail. The pain occafioned by the inflammatory aaion and tumor of parts bound down between the nail on one fide and the bone on the other, neither of which will yield, is faid to occafion fo much pain as to produce immediate delirium, and even death, ex- cept the parts are divided by a deep incifion; which muft pafs quite through the periofteum, as the inflam- mation is faid generally to exift beneath it. This dif- eafe is thus refembled by the procefs of toothing in young children; where an extraneous body lodged beneath the periofteum induces pain and fever, and fometimes delirium, and requires to be fet at liberty by the lancet. * ORDO Class II. i. 3.] OF SENSATION. 263 ORDO I. Increafed Senfation. GENUS III. With the Production of new Veffels by external Mem- branes or Glands, with Fever. The difeafes of this genus are perhaps all produc- tive of contagious matter; or which becomes fo by its expofure to the air, either through the cuticle, or by immediate contaa with it; fuch are the matters of the fmall-pox and meafles. The purulent matter, formed on parts covered from the air by thicker mem- branes or mufcles, as in the preceding genus, does not induce fever, and cannot therefore be called con- tagious ; but it acquires this property of producing fever in a few hours, after the abfcefs has been open- ed, fo as to admit the air to its furface, and may then be faid to confift of contagious miafmata. This kind of contagious matter only induces fever, but does not produce other matter with properties fimilar to its own ; and in this refpea it differs from the conta- gious miafmata of fmall-pox or meafles, but refembles thofe which have their origin in crowded jails; for thefe produce fever only, which frequently deftroys the patient; but do not produce other matters fimilar to themfelves; as appears from none of thofe, who died of the jail-fever, caught at the famous black af- fizes at Oxford, at the beginning of this century, having infeaed their phyficians or attendants. S4 tf 26+ DISEASES [Class II. i. 3. If indeed the matter has continued fo long as to become putrid, and thus to have given out air from a part of it, it acquires the power of producing fever; in the fame manner as if the ulcer had been opened, and expofed to the common air ; inftances of which are not unfrequent. And from thefe circumftances it feems probable, that the matters fecreted by the new veffels formed in all kinds of phlegmons, or puf- tules, are not contagious, till they have acquired fome- thing from the atmofphere, or from the gas produced by putrefaaion ; which will account for fome pheno- mena in the lues venerea, cancer, and of other con- tagious fecretions on the ikin without fever, to be mentioned hereafter. See Clafs II. 1. 4. 14. The theory of contagion has been perplexed by comparing it with fermenting liquors ; but the con- tagious material is fhewn in Seaion XXXIII. to be produced like other fecreted matters by certain ani- mal motions of the terminations of the veffels. Hence a new kind of gland is formed at the terminations of the veffels in the eruptions of the fmall-pox ; the ani- mal motions of which produce from the blood vario- lous matter; as other glands produce bile or faliva. Now if fome of this matter is introduced beneath the cuticle of a healthy perfon, or enters the circulation, and excites the extremities of the blood-veffels into thofe kinds of difeafed motions, by which it was itfelf produced, either by irritation or affociation, thefe dif- eafed motions of the extremities of the veffels will pro- duce other Similar contagious matter. See Sea. XXXIII. Class II. i. 3.] OF SENSATION. 265 XXXIII. 2. 5. and 9. Hence contagion feems to be propagated two ways ; one, by the ftimulus of con- tagious matter applied to the part, which by an un- known law of nature excites the ftimulated veffels to produce a fimilar matter ; as in venereal ulcers, which thus continue to fpread ; or as when variolous mat- ter is inferted beneath the cuticle ; or when it is fup- pofed to be abforbed, and diffufed over the body mixed with the blood, and applied in that manner to the cutaneous glands. The other way, by which con- tagion feems to be diffufed, is by fome diftant parts Sympathizing or imitating the motions of the part firft affeaed ; as the ftomach and Skin in the eruptions of the inoculated fmall-pox, or in the bite of a mad dog; , as treated of in Sea. XXII. 3.3. In fome of the difeafes of this genus the pulfe is ftrong, full, and hard, constituting the fenfitive irri- tated fever, as defcribed in the preceding genus; as in one kind of eryfipelas, which requires repeated venefeaion. In others the arterial aaion is fometimes moderate, fo as to constitute the fenfitive fever, as in the inoculated fmall-pox; where the aaion of the arteries is neither increafed by the fenforial power of irritation, as in the fenfitive irritated fever; nor de- creafed by the defea of that power, as in the fenfitive inirritated fever. But in the greateft number of the difeafes of this genus the arterial aaion is greatly diminifhed in refpea to Strength, and confequently the frequency of pulfation is proportionally increafed, as explained in Sea. XXXII. 2. 1. Which is owing to the deficiency of the fenforial power of irritation joined DISEASES [Class II. i. 5. j >!fled with the increafe of that of fenfation, and thus onftitutes the fenfitive inirritated fever; as in Scarla- tina with gangrenous tonfils. From this great debility of the aaion of the arte- ries, there appears to be lefs of the coagulable lymph or mucus fecreted on their internal furfaces; whence there is not only a defea of that buff or fize upon the blood, which is feen on the furface of that, which is drawn in the fenfitive irritated fever ; but the blood, as it cools, when it has been drawn into a bafon, fcarcely coagulates ; and is faid to be diffolved, and is by fome fuppofed to be in a ftate of aaual putre- faaion. See Sea. XXXIII. 1. 3. where the truth of this idea is controverted. But in the fevers of both this genus and the preceding one great heat is pro- duced from the chemical combinations in the fecre- tions of new veffels and fluids, and pain or uneafinefs from the distention of the old ones; till towards the termination of the difeafe fenfation ceafes, as well as irritation, with the mortification of the affeaed parts, and the death of the patient. Dyfenteria, as well as tonfillitis and aphtha, arc enumerated amongft the difeafes of external mem- branes, becaufe they are expofed either to the at- mofpheric air, which is breathed, and fwallowed with our food and faliva; or they are expofed to the in- flammable air, or hydrogen, which is generated in the inteftines; both which contribute to produce or pro- mote the contagious quality of thefe fluids; as men- tioned in Clafs II. 1. 5. It Class II. i. 3.] OF SENSATION. 267 It is not fpeaking accurate language, if we fay, that in the difeafes of this genus the fever is contagious; fince it is the material produced by the external mem- branes, which is contagious, after it has been ex- pofed to air; while the fever is the confequence of this contagious matter, and not the caufe of it. As appears from the inoculated fmall-pox, in which the fever does not commence, till after fuppuration ha* taken place in the inoculated arm, and from the dif- eafes of the fifth genus of this order, where con- tagion exifts without fever. See Clafs II. 1. 5. and II. 1. 3. 18. SPECIES. 1. Febris fenfitiva inirritata. Senfitive inirritated fever. Typhus gravior. Putrid malignant fever. Jail fever. The immediate caufe of this difeafe is the increafe of the fenforial power of fenfation, joined with the decreafe of the fenforial power of irritation ; that is, it confifts in the febris fenfitiva joined with the febris inirritativa of Clafs I. 2. 1. 1. as the febris fen- fitiva irritata of the preceding genus confifts of the febris fenfitiva joined with the febris irritativa of Clafs I. 1. 1. 1. In both which the word irritata, and in- irritata, are defigned to exprefs more or lefs irritation than the natural quantity ; and the fame when applied to fome of the difeafes of this genus. This fever is frequently accompanied with topical inflammation, which is liable, if the arterial ftrength is not fupported, to end in fphacelus; and as morti- fied * 268 DISEASES [Class II. i. 3. ficd parts, fuch as Sloughs of the throat, if they ad- here to living parts, foon become putrid from the warmth and moifture of their fituation ; thefe fevers have been termed putrid, and have been thought to owe their caufe to what is only their confequence. In hot climates this fever is frequently induced by the exhalations of Stagnating lakes or marflies, which abound with animal fubftances ; but which in colder countries produce fevers with debility only, as the quartan ague, without inflammation. The fenfitive inirritated, or malignant fever, is alfo frequently produced -by the putrid exhalations and Stagnant air in prifons; but perhaps moft frequently by contaa or near approach of the perfons, who have refided in them. Thefe caufes of malignant fevers contributed to produce, and to fupport for a while, the feptic and antifeptic theory of them ; fee Sea. XXXIII. 1. 3. The vibices or bruifes, and petechia? or purples, were believed to be owing to the diffolved ftate of the blood by its incipient putrefaaion ; but hydroftatical experiments have been made, which Shew the fizy blood of the patient in fenfitive irritated or inflammatory fever, with ftrong pulfe, is more fluid, while it is warm, than this uncoagulable blood taken in this fenfitive inirritated, or malignant fever ; from whence it is inferred, that thefe petechix, and vibices, are owing to the deficient power of abforption in the terminations of the veins. See Clafs I. 2. 1, 5. This fenfitive inirritated fever, or typhus gravior,. is diftinguiflied from the inirritative fever, or typhus tnitior, Class II. i. 3.] OF SENSATION. 269 mitior, in the early ftages of it, by the colour of the fkin; which in the latter is paler, with lefs heat, owing to the lefs violent aaion of the capillaries; in this it is higher coloured, and hotter, frorii the greater energy of the capillary aaion in the produaion of new veffels. In the more advanced ftate petechia?, and the produaion of contagious matter from inflamed membranes, as the aphtha? of the mouth, or ulcers of the throat, distinguishes this fever from the former. Delirium, and dilated pupils of the eyes, are more frequent in nervous fevers ; and ftupor with deafnefs more frequent attendants on malignant fevers. See ^m Clafs I. 2. 5. 6. There is another criterion difcernible by the touch of an experienced finger ; and that is, the coat of the artery in inflammatory fevers, both thefe attended with ftrength of pulfation, and thofe with weak pulfa- tion, feels harder, or more like a cord ; for the coats of the arteries in thefe fevers are themfelves inflamed, and are confequently turgid with blood, and thence are lefs e'dfily compreffed, though their pulfations are neverthelefs weak : when the artery is large or full with an inflamed coat, it is called hard ; and. when fmall or empty with an inflamed coat, it is called Sharp, by many writers. M. M. The indications of cure confift, 1. In pro- curing a regurgitation of any offenfive material, which may be lodged in the long mouths of the taaeals or lymphatics, or in their tumid glands, if** To excite the fyftem into neceffary aaion by the repeated exhi- bition 270 DISEASES [Class II. i. 3. bition of nutrientia, forbentia, and incltantia ; and to preferve the due evacuation of the bowels. 3. To prevent any unneceffary expenditure of fenforial power. 4. To prevent the formation of ulcers, or to promote the abforption in them, for the purpofe of healing them. 1. One ounce of wine of ipecacuanha, or about ten grains of the powder, fliould be given as an emetic. After a few hours three or four grains of calomel fhould be given in a little mucilage, or conferve. Where fomething fwallowed into the ftomach is the caufe of the fever, it is liable to be arrefted by the lym- phatic glands, as the matter of the fmall-pox inoculated in the arm is liable to be Stopped by the axillary lym- phatic gland ; in this fituation it may continue a day or two, or longer, and may be regurgitated during the operation of an emetic or cathartic into the Sto- mach or bowel, as evidently happens on the exhibi- tion of calomel, as explained in Sea. XXIX. 7. '2. For this reafon an emetic and cathartic, with venefec- tion, if indicated by the hardnefs and fulnefs of the pulfe, will very frequently remove fevers, if exhibited on the firft, fecond, or even third day. 2. Wine and opium, in fmall dofes repeated fre- quently, but fo that not the leaft degree of intoxica- tion follows, for in that cafe a greater degree of de- bility is produced from the expenditure of fenforial power in unneceffary motions. Many weak patients have been thus ftimulated to death. See Sea. XII. 7. 8. The Peruvian bark fliould be given alfo in re- peated * Class II. i. 3.] OF SENSATION 267 peated dofes in fuch quantity only as may Strengthen digeftion, not impede it. For thefe purpofes two ounces of wine, or of ale, or cyder, fhould be given every fix hours ; and two ounces of decoaion of bark, with two drachms of the tinaure of bark, and fix drops of tinaure of opium, fhould be given alfo every fix hours alternately ; that is, each of them four times in twenty-four hours. As much rhubarb as may in- duce a daily evacuation, fhould be given to remove the colluvies of indigefted materials from the bowels; which might otherwife increafe the diftrefs of the pa- tient by the air it gives out in putrefaaion, or by pro- ducing a diarrhcea by its acrimony ; the putridity of the evacuations are in confequence of the total inability of the digeftive powers; and their delay in the intef- tines, to the inaaivity of that canal in refpea to its peristaltic motions. The quantities of wine or beer and opium, and bark, above mentioned, may be increafed by degrees, if the patient feems refreffied by them ; and if the pulfe becomes flower on their exhibition ; but this with caution, as I have feen irrecoverable mifchief done by greater quantities both of opium, wine, and bark, in this kind of fever; in which their ufe is to ftrengthen the digeftion of the weak patient, rather than to Slop the paroxyfms of fever; but when they are adminiftered in intermittents, much larger quan- tities are neceffary. The ftimulus of fmall blifters applied in fucceffion, one every three or four days, when the patient be- comes 272 DISEASES [Class II. i. 3. comes weak, is of great fervice by ftrengthening digeftion, and by preventing the coldnefs of the ex- tremities, owing to the fympathy of the Skin with the Stomach, and of one part of the Skin with ano- ther. In refpea to nutriment, the patient Should be fup- plied with wine and water, with toafted bread, and fugar or fpice in it; or with fago with wine ; frefli broth with turnips, celery, parfley ; fruit; new milk. Tea with cream and fugar ;_ bread pudding, with le- mon juice and fugar; chicken, fifli, or whatever is grateful to the palate of the fick perfon, in fmall quantity repeated frequently ; with fmall beer, cyder and water, or wine and water, for drink, which may be acidulated with acid of vitriol in fmall quantities. 3. All unneceffary motions are to be checked, or prevented. Hence horizontal pofture, obfcure room, Silence, cool air. All the parts of the Skin, which feel too hot to the hand, Should be expofed to a current of cool air, or bathed with cold water, whe- ther there are eruptions on it or not. WaSh the patient twice a day with cold vinegar and water, or cold fait and water, or cold water alone, by means of a fponge. If fome parts are too cold, as the ex- tremities, while other parts are too hot, as the face or breaft, cover the cold parts with flannel, and cool the hot parts by a current of cool air, or bathing them as above. 4. For the healing of ulcers, if in the mouth, fo- lution of alum in water about 40 grains to an ounce, 4 or «las8II. i.3-!l OF SENSATION. 27$ or of. blue vitriol in water, one grain or two to an ounce may be ufed to touch them with three or four times a day. Of thefe perhaps a folution of alum is to be preferred, as it inftantly takes away the ftench from ulcers I fuppofe by combining with the volatile alkali which attends it. For this purpofe a folution of alum of an ounce to a pint of water fliould be frequently injeaed by means of a fyringe into the mouth. If there are ulcers on the external ikin, fine powder of bark feven parts, and ceruffa in fine pow- der one part, fhould be mixed, and applied dry on the fore, and kept on by lint, and a bandage. As floughs in the mouth are frequently produced by the previous drynefs of the membranes, which line it, this drynefs Should be prevented by frequently moiftening them, which may be effeaed by injeaion with a fyringe, or by a moift fponge, or laftly in the following manner. Place a glafs of wine and water, or of milk and fugar, on a table by the bed-fide, a little above the level of the moutji of the patient; then, having previoufly moistened a long piece of nar- row lifting, or cloth, or flannel, with the fame liquor, leave one end of it in the glafs, and introduce the other into the mouth of the patient; which will thus be fupplied with a conftant oozing of the fluid through the cloth, which aas as a capillary fyphon. The vifcid phlegm, which adheres to the tongue, fhould be coagulated by fome auftere acid, as by le- mon juice evaporated to half its quantity, or by crab- juice; and then it may be Scraped off by a knife, T or *7o DISEASES [Class II. i. 3. by them produce fimilar particles' ? Could they then have had a volcanic origin, or muft they not rather have been blown from putrid marflies full of animal matter ? But the greateft part of the folid earth has been made from animal and vegetable recrements, which may be difperfed by volcanoes..—Future difco- veries muft anfwer thefe queftions. As the fenfitive fever attending thefe epidemic ca- tarrhs is feldom either much irritated or inirritated, venefeaion is not always either clearly indicated or forbid ; but as thofe who have died of thefe catarrhs have generally had inflamed livers, with confequent fuppuration in them, venefeaion is advifable, wherever the cough and fever are greater than common, fo as to render the ufe of the lancet in the leaft dubious. And in fome cafes a fecond bleeding was neceffary, and a mild cathartic or two with four grains of calo- mel ; with mucilaginous fubacid diluents; and warm fleam occafionally to alleviate the cough, finifhed the cure. The catarrhus contagiofus is a frequent difeafe amongft horfes and dogs; it feems firft to be diffemi- nated amongft thefe animals by miafmata diffufed in the atmofphere, becaufe fo many of them receive it at the fame time; and afterwards to be communicable from one horfe or dog to another by contagion, as above defcribed. Thefe epidemic or contagious ca- tarrhs more frequently occur amongft dogs and horfes than amongft men ; which is probably owing to the greater extenfion and fenfibility of the mucous mem- brane, Class II. i. 3.] OF SENSATION. 291 brane, which covers the organ of fmell, and is dif- fufed over their wide noftrils, and their large maxillary and frontal cavities. And to this circumftance may be afcribed the greater fatality of it to thefe animals. In refpea to horfes, I fufpea the fever at the be- ginning to be of the fenfitive, irritated, or inflammatory kind, becaufe there is fo great a difcharge of purulent mucus; and that therefore they will bear once bleed- ing early in the difeafe ; and alfo one mild purgative, confifting of about half an ounce of aloe, and as much white hard foap, mixed together. They fliould be turned out to grafs both day and night for the benefit of pure air, unlefs the weather be too cold fand in that cafe they fhould be kept in an open airy flable, without being tiedjl, that they may hang down their heads to facilitate the difcharge of the mucus from their noftrils. Grafs fhould be offered them, or other frefli vegetables, as carrots and potatoes, with mafhes of malt, or of oats, and with plenty of frefh warm or cold water frequently in a day. When fymptoms of debility appear, which may be known by the coldnefs of the ears or other extremities, or when floughs can be feen on the membrane which lines the noftrils, a drink confifting of a pint of ale with half an ounce of tinaure of opium in it, given every fix hours, is likely to be of great utility. In dogs I believe the catarrh is generally joined with fymptoms of debility early in the difeafe. Thefe animals Should be permitted to go about in the open air, and fliould have conftant accefs to frefli water. U 2 The -■$; DISEASES [Class II. r. 3. The ufe of being as much as may be in the air is evident, becaufe all the air which they breathe paffes twice over the putrid floughs of the mortified parts of the membrane which lines the noftrils, and the maxillary and frontal cavities; that is, both during infpiration and expiration ; and muft therefore be loaded with contagious particles. Frefh new milk, and frefli broth, fliould be given them very frequently, and they fliould be fuffered to go amongft the grafs, which they fometimes eat for the purpofe of an emetic ; and if poffible fhould have accefs to a running ftream of water. As the contagious mucus of the noftrils, both of thefe animals and of horfes, generally drops into the water they attempt to drink. Bits of raw flefli, if the dog will eat them, are preferred to cooked meat ; and from five to ten drops of tinaure of opium may be given with advantage, when fymptoms of de- bility are evident, according to the fize of the dog, every fix hours. If floughs can be feen in the noftrils, they Should be moiftened twice a day, both in horfes and dogs, with a folution of fugar of lead, or of alum, by means of a fponge fixed on a bit of whale bone, or by a fyringe. The lotion may be made by dif- folving half an ounce of fugar of lead in a pint of water. Ancient philofophers feem to have believed, that the contagious miafmata in their warm climates affeaed horfes and dogs previous to mankind. If thofe con- tagious particles were fuppofed to be diffufed amongft the heavy inflammable air, or carbonated hydrogen, of putrid Class II. r. 3.] OF SENSATION. ^; putrid marines, as thefe animals hold their heads down lower to the ground, they may be fuppofed to have received them fooner than men. And though men and quadrupeds might receive a difeafe from the fame fource of marlh-putrefaaion, they might not after- wards be able to infea each other, though they might infea other animals of the fame genus; as the new contagious matter generated in their own bodies might not be precifely fimilar to that received ; as happened in the jail-fever at Oxford, where thofe who took the contagion and died, did not infea others. On mules and dogs the infe ftances of a confluent fmall-pox in inoculation follow- ing a violent purging induced by too large a dofe of calomel. Secondly, the matter ufed for inoculation fliould be in a fmall quantity, and warm, and fluid. Hence it is belt when it can be recently taken from a patient in the difeafe ; or otherwife it may be diluted with part of 3©4 DISEASES [Class II. i. 3. of a drop of warm water, fince its fluidity is likely to occafion its immediate abforption ; and the wound lliould be made as fmall and fuperficial as poffible, as otherwife ulcers have been fuppofed fometimes to en- fue with fubaxillary abfceffes. Add to this, that the making two punaures either on the fame, or one on each arm, fecures the fuccefs of the operation in re- fpea to communicating the infeaion. Thirdly, at the time of the fever or eruption the application of cool air to thofe parts of the Skin, which are too warm, or appear red, or are covered with what is termed a ralh, fliould be ufed freely, as well as during the whole difeafe. And at the fame time, if the feet or hands are colder than natural, thefe fhould be covered with flannel. See Clafs IV. 2. 2. 10. 10. Rubeola irritata, ?norbilli. The meafles com- mence with fneezing, red eyes, dry hoarfe cough, and is attended with fenfitive irritated fever. On the fourth day, or a little later, fmall thick eruptions ap- pear, fcarcely eminent above the Skin, and, after three days, changing into very fmall branny fcales. As the contagious material of the fmall-pox may be fuppofed to be diffufed in the air like a fine dry pow-; der, and mixing with the faliva in the mouth to infea the tonfils in its paffage to the Stomach ; fo the con- tagious material of the meafles may be fuppofed to be more completely diffolved in the air, and thus to im- part it* poifon to :hr membrane of the noftrils, which 4 covers Class II. i. 3.] OF SENSATION. 305 covers the fenfe of fmell; whence a catarrh with fneezing ufliers in the fever ; the termination of the nafal dua of the lacrymal fac is fubjea to the fame ftimulus and inflammation, and affeas by fympathy the lacrymal glands, occafioning a great flow of tears. See Sea. XVI. 8. And the rednefs of the eye and eyelids is produced in confequence of .the tears being in fo great quantity, that the faline part of them is not entirely reabforbed. See Sea. XXIV. 2. 8. The contagion of the meafles, if it be taken a fuf- ficient time before inoculation, fo that the eruption may commence before the variolous fever comes on, ftops the progrefs of the fmall-pox in the inoculated wound, and delays it till the meafle-fever has finifhed its career. See Sea. XXXIII. 2. 9. The meafles are ufually attended with inflamma- tory fever with ftrong pulfe, and bear the lancet in every ftage of the difeafe. In the early periods of it, venefeaion renders the fever and cough lefs; and, if any fymptoms of peripneumony occur, is repeat- edly neceffary ; and at the decline of the difeafe, if a cough be left after the eruption has ceafed, and the fubfequent branny fcales are falling off, venefec- tion Should be immediately ufed ; which prevents the danger of confumption. At this time alfo change of air is of material confequence, and often removes the cough like a charm, as mentioned in a fimilar fitua- tion at tlie end of the chin-cough. Rubeola inirritata. Meafles with inirritated fever, or with weak pulfe, has been fpoken of by fome wri- X ters. 306 DISEASES [Class II. *. 3, ters. See London Med. Obferv. Vol. IV. Art. XI. It has alfo been faid to have been attended with fore throat. Edinb. Effays, Vol. V. Art. II. Could the icarfet fever have been miftaken for the meafles ? or might one of them have fucceeded the other, as in the meafles and fmall-pox mentioned in Sea. XXXIII. 2. 9. ? From what has been faid, it is probable that inocu- lation might difarm the meafles as much as the fmall- pox, by preventing the catarrh and frequent pulmo- nary inflammation, which attends this difeafe ; both of which arc probably the confequence of the imme- diate application of the contagious miafmata to thefe membranes. Some attempts have been made, but a difficulty feems to arife in giving the difeafe ; the blood, I conjeaure, would not infea, nor the tears ; perhaps the mucous difcharge from the noftrils might fucceed ; or a drop of warm water put on the erup- tions, and feraped off again with the edge of a lancet; or if the branny fcales were colleacd, and moiftened with a little warm water? Further experiments on this fubjea would be worthy the public attention. 11. Scarlatina mitis. The fcarlet fever exifts with all degrees of virulence, from a flea-bite to the plague. The infeaious material of this difeafe, like that of the fmall-pox, I fuppofe to be diffufed, not diffolved, in the air; on which account I fufpea, that it requires a much nearer approach to the fick, for a well per- fon to receive the infection, than in the meafles; .the contagion Class II. I. 3.] OF SENSATION. 307 contagion of which I believe to be more volatile, or diffufible in the atmofphere. But as the contagious miafmata of fmall-pox and fcarlet fever are fuppofed to be more fixed, they may remain for a longer time in clothes or furniture ; as a thread dipped in vario- lous matter has given the difeafe by inoculation after having been expofed many days to the air, and after having been kept many months in a phial. This alfo accounts for the flow or fporadic progrefs of the fear- „ let fever, as it infeas others at but a very fmall dif- tance from the fick ; and does not produce a quantity of pus-like matter, like the fmall-pox, which can ad- here to the clothes of the attendants, and when dried is liable to be fhook off in the form of powder, and thus propagate the infeaion. This contagious powder of the fmall-pox, and of the fcarlet fever, becomes mixed with faliva in the mouth, and is thus carried to the tonfils, the mucus of which arrefts fome particles of this deleterious ma- terial ; while other parts of it are carried into the ftomach, and are probably decompofed by the power of digeftion ; as feems to happen to the venom of the viper, when taken into the ftomach. Our per- ception of bad taftes in our mouths, at the fame time that we perceive difagrceable odours to our nof- trils, when we inhale very bad air, occafions us to fpit out our faliva; and thus, in fome inftances, to preferve ourfelves from infeaion. This has been fup* pofed to originate from the fympathy between the organs of tafte and fmell; but any one-who' goes into X 2 -a fick 30S DISEASES [Class II. i. 3. a fick room clofe fhut up, or into a crowded affembly- room, or tea-room, which is not fufficiently ventilated, may eafily mix the bad air with the faliva on his tongue fo as to tafte it; as I have myfelf frequently attended to. Hence it appears that thefe heavy infeaious matters are more liable to mix with the faliva, and inflame the tonfils, and that either before or at the commencement o'" the fever ; and this is what generally happens ift the fcarlet fever, always I fuppofe in the malignant kind, and very frequently in the mild kind. But as this infeaion may be taken by other means, as by the ikin, it alfo happens in the moft mild kind, that there is no inflammation of the tonfils at all; in the fame manner as there is generally no inflammation of the toniils in the inoculated fmall-pox. In the mild Scarlatina on the fourth day of the fever the face fwells a little, at the fame time a florid red- nefs appears on various parts of the Skin, in large blotches, at length coalefcing, and after three days changing into branny fcales. M. M. Cool air. Fruit. Lemonade. Milk and water- Scarlatina maligna. The malignant fcarlet fever begins with inflamed tonfils; which are fucceeded by ' dark drab-coloured floughs three or five lines in dia- meter, flat, or beneath the furrounding furface ; and which conceal beneath them Spreading gangrenous nkers. The fwellings of the tonfils are fenfible to the eye Class «. i. 3 J OF SENSATION. 3°9 eye and touch externally, and have an elaftic rather than an ocdematous feel, like parts in the vicinity of o-angrenes. The pulfe is very quick and weak, with delirium, and the patient generally dies in a few days ; or if he recovers, it is by flow degrees, and attended with anafarca. M. M. A vomit once. Wine. Beer. Cyder. Opium. Bark, in fmall repeated dofes. Small, fuc- ceffive blifters, if the extremities are cooler than natu- ral. Cool air on the hot parts of the ikin, the cool extremities being at the fame time covered. Iced lemonade. Broth. Cuftards. Milk. Jellies. Bread pudding. Chicken. Touch the ulcers with a dry fponge to abforb the contagious matter, and then with a fponge filled with vinegar, with or without fugar of lead diffolved in it, about fix grains to an ounce ; or with a very little blue vitriol diffolved in it, as a grain to an ounce; but nothing fo inftantaneoufly correas the putrid fmell of ulcers as a folution of alum, about half an ounce to a pint of water, which Should be a little warmiSh, and injeaed into the fauces gently by means of a fyringe. Thefe Should be repeated fre- quently in a day, if it can be done eafily, and without fatigue to the child. A little powder of bark taken frequently into the mouth, as a grain or two, that it may mix with the faliva, and thus frequently ftimulate the dying tonfils. Could a warm bath made of de- coaion of bark, or a cold fomentation with it, be of Service? Could oxygsne gas mixed with common air Stimulate the languid fyftem ? Small elearic fliocks X 3 through 3io DISEASES [Class II. i. 3, through the tonfils every hour ? ether frequently ap- plied externally to the Swelled tonfils ? As this difeafe is attended with the greateft degree of debility, and as Stimulant medicines, if given in quantity, fo as to produce more than natural warmth, contribute to expend the already too much exhaufted fenforial power; it appears, that there is nothing fo neceffary to be nicely attended to, as to prevent any unneceffary motions of the fyftem ; this is beft accom- plifhed by thp application of cold to thofe parts of the Skin, which are in the leaft too hot. And fe- condly, that the exhibition of the bark in fuch quan- tity, as not to opprefs the ftomach and injure digef- tion, is next to be attended to, as not being liable to increafe the aaions of the fyftem beyond their natural quantity; and that opium and wine fliould be given with the greateft caution, in very fmall repeated quan- tity, and fo managed as to prevent, if poflible, the cold fits of fever; which probably occur twice in 25 hours, obeying the lunations like the tides, as men- tioned in Sea. XXXII. 6, that is, I fuppofe, the cold periods, and confequent exacerbations of fever, in this malignant fcarlatina, occur twice in a lunar day ; which is about ten minutes Jefs than 25 hours; fo that if the commencement of one cold fit be marked, the commencement of the next may be expeaed, if not difturbed by the exhibition of wine or opium, or the application of blifters, to occur in about twelve hours and a half from the commencement of the for- mer •* or if not prevented by large dofes of the bark. No Class II. i. 3 ] OF SENSATION. 3n No one could do' an aa more beneficial to fociety, or glorious to himfelf, than by teaching mankind how to inoculate this fatal difeafe; and thus to deprive it of its malignity. Matter might be taken from the ulcers in the throat, which Would probably'convey the contagion. Or warm water might be put on the eruption, and fcraped off again by the edge of a lan- cet. Thefe experiments could be attended with no danger, and Should be tried for the public benefit, and the honour of medical fcience. 12. Miliaria. Miliary fever. An eruption pro- duced by the warmth, and more particularly by the ftimulus of the points of the wool in flannel or blan- kets applied to the Skin, has been frequently obferved ; which, by cool drefs, and bed-clothes without flan- nel, has foon ceafed. See Clafs I. i, 2. 3. This, which may be called miliaria fudatoria, has been con- founded with other miliary fevers, and has made the exiftence of the latter doubted. Two kinds of erup- tions I have feen formerly attended with fever, but did not fufficiently mark their progrefs, which I con- ceived to be miliary eruptions, one with arterial ftrength, or with fenfitive irritated fever, and the other with arterial debility, or with fenfitive inirritated fever. In the former of thefe, or miliaria irritata, the eruptions were diftina and larger than the fmall-pox, and the fever was not fubdued without two or three vcnefeaions, and repeated cathartics with calomel. X 4 The. 312 DISEASES [Class II. 1.3. The latter, or miliaria inirritata, was attended with great arterial debility; and during the courfe of the fever pellucid points appeared within the fkin, par- ticularly on the foft parts of the fingers. And, in one patient, whom I efteemed near her end, I well recol- fea to have obferved round pellucid globules; like what are Often feen on vines in hot-houfe$; no larger than the fmaHeft pins' heads, adhere to her neck and bofom ; which were hard to the touch, but were eafity rubbed off. Thefe difeafes, if they are allied, do not differ more than the kinds of fmall-pox ; but require many further obfervations. The eruption fo often feen ori children in the cradle, and called by t)ie nurfes red-gum; and which is at- tended with, fome degree of fever, I fufp'ea to be pro- duced by too great warmth, and the contaa of flannel next their tender Skins, like the miliaria fudatoria ; and like that requires cool air, cool clothes, and linen next their Skin, 13. Pefilis, The plague, like other difeafes of this clafs, feems to be fometimes mild, and fometimes ma- lignant ; according to the testimony of different wri- ters. It is faid to be attended with inflammation, with the greateft arterial debility, and to be very con- tagious, attended at an uncertain time of the fever with buboes and carbuncles. Some authors affirm, that the contagion of the plague may be repeatedly received, fo as to produce the difeafe; but as this H contrary to the general analogy of all contagious difeafes, Class II. i. 3.] OF SENSATION. 313 difeafes, which are attended with fever, and which cure themfelves fpontan'eoufly; there is reafon to fuf- pca, that where it has been fuppofed to have been repeatedly received, that fome other fever with arte- rial debility has been miftaken for it, as has probably univerfally been the cafe, when the fmall-pox has been faid to have been twice experienced. M. M. Venefeaion has been recommended by fome writers on the firft day, where the inflammation was fuppofed to be attended with fufficient arterial Strength, which might perhaps fometimes happen, as the bubo feems to be a fuppuration; but the carbuncle, or an- thrax, Is a gangrene of the part, and Shews the greateft debility of circulation. Whence all the means before enumerated in this genus of difeafes to fupport the powers of life are to be administered. Currents of cold air, cold water, ice, externally on the hot parts of the Skin. Tlie methods of preventing the fpreading of this difeafe have been much canvaffed, and feem to conSift in preventing all congregations of the people, as in churches, or play-houfes ; and to remove the fick into tents on fome airy common by the fide of a river, and fupply them with frefli food, both animal and vege- table, with beer and wine in proper quantities, and to encourage thofe who can, daily to wafh both their clothes and themfelves. The pefilis vaccina, or difeafe amongft the cows, which affliaed this iiland about half a century ago, feems to have been a conir.gious fever with great ar- terial 314 DISEASES [Class II. x. j. terial debility; as in fome of them in the latter ftage of the difeafe, an emphyfema could often be felt in fome parts, which evinced a confiderable progrefs of gangrene beneath the ikin. In the fenfitive inirritated fevers of thefe animals, I fuppofe about fixty grains of opium, with two ounces of cxtraa of oak-bark, every fix hours, would fupply them with an efficacious medicine ; to which might be added thirty grains of vitriol of iron, if any tendency to bloody urine fhould appear, to which this animal is liable. The method of preventing the infeaion from fpreading, if it fhould ever again gain accefs to this ffland, would be imme- diately to obtain an order from government to prevent. any cattle from being removed, which were found within five miles of the place fuppofed to be infeaed, for a few days; till the certainty of the exiftence of the peftilence could be afcertained, by a committee of medical people. As foon as this was afcertained, all the cattle within five miles of the place fhould be im- mediately flaughtered, and confumed within the cir- cumfcribed diftria; and their hides put into lime-water before proper infpeaors. 14. Pemphigus is a contagious difeafe attended with bladdery eruptions appearing on the fecond or third day, as large as filberts, which remain many days, and then effufe a thin ichor. It feems to be either of a mild kind with fenfitive fever only, of which I have feen two inftances, or with irritated, or with inirri- tated fever, as appears from the obfervations of M. Salabert. Class II. i. 3 J OF SENSATION. 315 Salabert. See Medical Comment, by Dr. Duncan, Decad. II. Vol. VI. 15. Varicella. Chicken-pox is accompanied with fenfitive fever, puftulcs break out after a mild fever like the fmall-pox, feldom fuppurate, and generally terminate in fcales without fears. I once faw a lady, who mifcarried during this difeafe, though all her children had it as Slightly as ufual. It fometimes leaves fears or marks on the fkin. This difeafe has been miftaken for the Sinall-pox, and inoculated for it; and then the fmall pox has been fuppofed to hap- pen twice to the fame perfon. Sec Tranf. of the Col- lege, London. It is probable that the pemphigus and urticaria, as well as this difeafe, have formerly been difeafes of more danger ; which the habit of innume- rable generations may have rendered mild, and will in procefs of time annihilate. In the fame manner as the fmall-pox, the venereal difeafe, and rickets, feem to become milder or lefs in quantity every half cen- tury. While at the fame time it is not improbable, that other new difeafes may arife, and for a feafon thin mankind! 16. Urticaria, Nettle-rafli begins with mild fen- fitive fever, which is fometimes fcarcely perceptible. Hence this eruption has been thought of two forts, one with and the other without fever. On the fecond day red fpots, like parts Stung with nettles, are feen; which almoft vanifh during the day, and recur in the evening 3i<5 DISEASES [Class IT. i. 3. evening with the fever, fucceeded in a few days by very minute fcales. See Tranf. of the College, Lon- don. 17. Aphtha. Thrufh. It has been doubted, whether aphtha or thrufh, which confifts of ulcers in the mouth, fliould be enumerated amoftgft febrile difeafes; and whether thefe ulcers are always fymptofflatic, Or the confequence rather than the caufe of the fevers which attend them. The tongue becomes rather Swelled ; its colour and that of the fauces purplifh ; floughs or ulcers appear firft on the throat and edges of the tongue, and at length over the whole mouth. Thefe floughs are whitifh, fometimes diftina, often coalefcing, and remain an uncertain time. Cullen. I Shall con- cifely mention four cafes of aphtha, but do not pretend to determine whether they were all of them fympto- matic or original difeafes. Aphtha fenfitiva. A lady during pregnancy was frequently feized with ulcers on her tongue and cheeks, or other parts of the mouth, without much apparent fever; which continued two or three weeks, and returned almoft every month. The thrufli in the mouths of young children feems to be a fimilar difeafe. Thefe ulcers refertible thofe produced in the fea-fcurvy, and have probably for their caufe an increafed aaion of the fecerning fyftem from increafed fenfation, with a decreafed aaion of the abforbent fyftem from de- creafed irritation. See Clafs I. 2. 1. 14. M. M. So- Class II. i. 3.] OF SENSATION. 3,7 M. M. Solutions of alum, of blue vitriol. Powder of birk taken frequently into the mouth in very fmall qn,.: dty. See Clafs II. 1. 3. 1. Aphtha irritata. Inflammatory aphtha. A cafe of this kind is related under the title of fuppurative rheumatifm. Clafs IV. 2. 1. 16. Aphtha inirritata. Sloughs or ulcers of the mouth, attended with fenfitive fever with great arterial debi- lity. They feem to fpread downwards from the tkroat into the Stomach, and probably through the whole inteftinal canal, beginning their courfe with cardialgia, and terminating it with tenefmus ; and might perhaps be called an eryfipelas of this mucous membrane. M. M. Cool air. A fmall blifter on the back. Bark. Wine. Opium in fmall repeated quantities. Soap neutralizes the gaftric acid without effervefeence, and thus relieves the pain of cardialgia, where the ftomach is affeaed. Milk alfo deftroys a part of this acid. Infufion of fage leaves two ounces, almond foap from five grains to ten, with fugar and cream, is gene- rally both agreeable and ufeful to thefe patients. See I. 2. 4. 5. Where the ftomach may be fuppofed to be exco- riated by poifons containing acid, as fublimate of mer- cury or arfenic; or if it be otherwife inflamed, or very fenfible to the Stimulus of the gaftric acid; or where it abounds with acid of any kind, as in cardi- algia ; the exhibition of foap is perhaps a preferable manner of giving alkali than any other, as it decom- pofes in the ftomach without effervefeence; while the cauftic alkali is too acrid to be administered in fuch cafes, 3*8 Diseases [Classit. t.$. cafes, and the mild alkali produces carbonic gas. If a drop of acid of vitriol be put on cap paper, it will be long before it deftroys the paper; but if a drop of mild alkali be added, a fudden effervefeence arifes, and the paper is inftantly deftroyed by the efcape of the fixed air ; in the fame manner as lumps of folid lime are broken into powder by the efcape of the fleam produced from the water, which is poured on them. This Shows why a fucceffion of acid and of alkaline cauftics fooner deftroys a part, than either of them applied feparately. 18. Dyfenteria. Bloody-flux \i attended with fenfi- tive fever generally with arterial debility; with frequent mucous or bloody ftools ; which contain contagious matter produced by the membranes of the inteftines; the alimentary excrement being neverthelefs retained; with griping pains and tenefmus. ' M. M. Emetics, Antimonials, Peruvian bark. Opium and calomel of each a grain every night. Bolus arme- nia?. Earth of alum. Chalk. Calcined hartfliom. Mucilage. Bee's wax mixt with yolk of egg. Cera- ted glafs of Antimony. Warm bath. Flannel cloath- ing next to the fkin. Large clyfters with opium. With ipecacuanha, with fmoke of tobacco ? Two dyfenteric patients in the fame ward of the infirmary at Edinburgh quarrelled and whipped each other with horfewhips a long time, and were both much better after it, owing perhaps to the exertion of fo much of the fenforial power of volition ; which, like real infanity, added excitement to the whole fyftem. The *lass II. x. 3.3 OF SENSATION. 3-T9 The prevention of this contagion muft confift prin- cipally in ventilation and cleanlinefs ; hence the patients fhould be removed into cottages diftant from each other, or into tents; and their faeces buried as foon as may be ; or conveyed into a running ftream ; and themfelves fhould be wafhed with cold or warm water after every evacuation. For the contagious matter confifts in the mucous or purulent difcharge from the membrane which lines the inteftines; and not from the febrile perfpiration, or breath of the patients. For the fever is only the confequence and not the caufe of contagion ; as appears from Genus the Fifth of this Order, where contagion exifts without fever. 19. Gaftritis fuperficialis. Superficial inflammation of the ftomach. An eryfipelatous inflammation of the ftomach is mentioned by Dr. Cullen from his own obfervation8; which is diftinguifhed from the inflam- matory gaftritis by lefs pain and fever, and by an eryfipelatous rednefs about the fauces. Does this difeafe belong to aphtha ? 20. Enteritis fuperficialis. Superficial inflammation of tlie bowels is alfo mentioned by Dr. Cullen from his own obfervation under the name of enteritis ery- rhematica ; and is faid to be attended with lefs pain and fever, without vomiting, and with diarrhcea. May 20I this difeafe be referred to aphtha, or to dyfentery ? ORD<> 3*o DISEASES [Class II. r. 4. ORDO I. Increafed Senfation. GENUS IV. With the Production of new Veffels by internal Membranes or Glands, without Fever. Where, inflammation is produced in a fmall part, which has not great natural fenfibility, the additional fenfation does not produce an increafed aaion of the arterial fyftem ; that is, the affociated motions which are employed in the circulation of the blood, thofe for inftance of the heart, arteries, glands, capillaries, and their correspondent veins, are not thrown into increafed aaion by fo fmall an addition of the fenforial power of fenfation. But when parts, which naturally poffefs more .fenfibility, become inflamed, the quantity of the fenforial power of fenfation becomes fo much increafed, as to affea the affociated motions belonging to the circulation, occasioning them to proceed with greater frequency ; that is, a fever is induced. This is well exemplified in the internal and fuperficial paronychia, one of which is attended with great pain and fever, and the other with little pain and no fever. See Clafs II. 1. 2. 19. and II. 1. 4. 5. From hence it appears, that the fenfitive fever is an accidental confequence of the topical phlegmon, or inflammation, and not a caufe of it; that it is often injurious, but never falutary ; and fliould therefore always be extinguished, as foon as may be, either by 1 the Glass II. i. 4.] OF SENSATION. 321 the lancet and cathartics, and diluents, and cold air, when it is of the irritated kind ; or by the bark, opium, cool air, and nutrientia, when it is of the inirritated kind. SPECIES. 1. Ophthalmia fuperficialis. As the membranes, which cover the eye, are excluded from the air about one third part of the twenty-four hours; and are moi- stened by perpetual niaitation during the other fixteen; they may be confidered as Internal membranes; and from the analogy of their inflammation to that of other internal membranes, it is arranged under this genus; whilft the tonfillitis \s efteemed an inflammation of an external membrane, becaufe currents of air are per- petually paffmg both day and night over the fauces. The fuperficial ophthalmy has generally been ef- teemed a fymptom of fcrophula, when it recurs fre- quently in young perfons; but is probably only a concomitant of that difeafe, as a fymptom of general debility; ramifications of new red veffels, and of enlarged old ones, are fpread over the white part of the eye; and it is attended with lefs heat, lefs pain, and lefs intolerance of light than the ophthalmia in- terna, defcribed in Clafs II. 1. 2. 2, It occurs in thofe of feeble circulation, efpecially children of a fcrophulous tendency, and feems to arife from a pre- vious torpor of the veffels of the tunica albuginea from their being expofed to cold air ; and from this torpor being more liable to occur in habits, which Y are 322 DISEASES [Class II. i. 4. are naturally inirritable ; and therefore more readily fall into quiefcence by a Smaller deduaion of the Stimulus of heat, than would affea ftronger or more irritable habits; the confequence of this torpor h increafed aaion, which produces pain in the eye, and th..t induces inflammation by the acquisition of the additional fenforial power of fenfation. Ophthalmia lymphatica is a kind of anafarca of the tunica adnata ; in this the veffels over the fclerotica, or white part of the eye, rife considerably above the cornea, which they Surround, are lefs red than in the ophthalmia fuperficialis, and appear to be fwelled by an accumulation of lymph rather than of blood ; it is probably owing to the temporary obftruaion of a branch of the lymphatic fyftem. M. M. If the pain be great, venefeaion by leeches on the temple, or cutting the temporal artery, and one purge with three or four grains of calomel Should be premifed. Then the Peruvian bark twice a day. Opium from a quarter to half a grain twice a day for fome weeks. Bathe the eye frequently with cold water alone, or with cold water, to a pint of which is added half an ounce of fait. White vitriol fix grains diffolved in one ounce of water ; a drop or two to be put between the eyelids twice a day. Take very I fmall elearic fparks from the eyes every day for a fortnight. Bathe the whofe head with fait and water made warm every night for fome months. Send fuch children to a fchool near the fea for the convenience of fea-bathing for many months annually ; fuch fchook are to be found in or near Liverpool. Whea Class II. i. 4] OF SENSATION* 323 When a child is aflliaed with an inflamed eye of this kind, he Should always fit with his back to the window or candle; but it is generally not neceffary to cover it, or if the uneafy fenfation of light makes this proper, the cover fliould ftand off from the eye, fo as not much to exclude the cool air from it. As covering an eye unneceffarily is liable to make that eye weaker than the other, from its not being fuflici* ently ufed, and thence to produce a fquinting for ever afterwards. Neverthelefs, when the pain is great, a poultice muft be applied to keep the eyes moift, or a piece of oiled filk bound lightly over them. Or thus, boil an egg till it is hard, cut it longitudinally into two hemif- pheres, take out the yolk, few the backs of the two hol- low hemifpheres of the white to a ribbon, and bind them over the eyes every night on going to bed; which, if nicely fitted on, will keep the eyes moift with- out any difagreeable preffure. See Clafs I. 1. 3. 14. Ophthalmia equina. An inflammation of this kind is liable to affea the eyes of horfes; one caufe of which is owing to a filly cuftom of cutting the hair out of horfes' ears ; by which they are not only lia- ble to take cold at the ear, but grafs feeds are liable to fall into their ears from the high racks in ftables; and in both cafes the eye becomes inflamed by fym- pathy. I once dlreaed the temporal artery of a horfe to be opened, who had frequent returns of an in- flamed eye ; and I believed it was of effential fervice to him; it is probable that the artery was afterwards Y 2 contraaed 3H DISEASES [Class II. i. + contraaed in the wounded part, and that thence lefs blood was derived to the eye : the haemorrhage was Stopped by two perfons alternately keeping their fin- gers on the orifice, and afterwards by a long bandage of broad tape. 2. Pterigion. Eye-wing. A fpot of inflammation fometimes begins on the infide of the lower' eyelid, or on the tunica albuginea, and fpreads an intertex- ture of red veffels from it, as from a center, which extend on the white part of the eye, and have the appearance of the wing of a fly, from whence its name. M. M. Cut the ramifications of veffels again and again with the point of a lancet clofe to the centre of inflammation. 3. Tarfitis palpebrarum. Inflammation of the edges of the eyelids. This is a difeafe of the glands, which produce the hairs of the eyelaflies, and is frequently the caufe of their falling off. After this inflammation a hard fear-like ridge is left on the edge of the eyelid, which fcratches and inflames the eyeball, and becomes a very troublefome difeafe. The Turkish ladies are faid to colour the edge of the eyelafli with crude antimony In very fine powder, which not only gives luftre to the eye, as a diamond fet on a black foil, but may prevent extraneous light from being reflcfted from thefe edges into the eye, and thus ferve the purpofe of the black feathers about fhe eyes of fwans, defcribed in Sea. XXXIX. 5. ?. and Class II. i. 4 ] OF SENSATION. 325 and may alfo prevent the edges of the eyelids from being inflamed by the frequent ftimulus of tears on them. Black lead in fine powder might be better for all thefe purpofes than antimony, and might be put on with a camel's hair brulh. M. M. Mercurial ointment Smeared at night on the edges of the eyelids. Burnt alum Sixty grains, hog's greafe half an ounce, well rubbed into an ointment to be Smeared on them in the night. Cold water frequently in the day. See Clafs IL 1. 1. 8, 4. Hordeolum. Stye. This inflammation begins either on or near the edges of the eyelids, or in the loofe Skin of them, and is fometimes very Slow either in coming to fuppuration or in difperfing. The Skin beneath the lower eyelid is the moft frequent feat of this tumor, which fometimes never fuppurates at all, but becomes an incyfted tumor: for as this Skin is very loofe for the purpofe of admitting great motion to the eyelid, the abforbent power of the veins feems particularly weak in this part; whence when any per- fon is weakened by fatigue or otherwife, a darker Shade of colour is feen beneath the eyes; which is owing to a lefs energetic aaion of the abforbent ter- minations of the veins, whence the currents of cb rk or venous blood are delayed in them, This dark Shade beneath the eyes, when it is permanent, is a fymptom of habitual debility, or inirritability of the circulating fyftem. See Clafs I. 2. 2. 2. !\J. M. Smear the tumors with mercurial ointment, Y 3 moiften 326 DISEASES [Class II. i. 4. moiften them frequently with ether. To promote their fuppuration they may be wounded with a lancet, or flit down the middle, or they may be cut out. A cauftic leaves a large fear. Paronychia fuperficialis. Whitlow. An inflamma- tion about the roots of the nail beneath the ikin, which fuppurates without fever, and fometimes de- ftroys the nail ; which is however gradually repro- duced. This kind of abfcefr, though not hfelf dan- gerous, has given opportunity for the inoculation of venereal matter in the hands of accoucheurs, and of putrid matter from the diffeaion of difeafed bodies ; and has thus been the caufe of difeafe and death. When putrid matter has been thus abforbed from a dead body, a livid line from the finger to the Swelled gland in the axilla is faid to be vifible ; which Shews the inflammation of the abforbent veffel along its whole courfe to the lymphatic gland; and death has gene- rally been the confequence. M. M. In the common paronychia a poultice is generally fufficient. In the abforption of putrid matter rub the whole hand and arm with mercurial ointment three or four times a day, or perpetually. Could the fvvelled axillary gland be exfeaecl ? In the ab. forption of venereal matter the ufual methods of cure in Syphilis muft be administered, as in Clafs II. 1.5. 1. 6. Gutta rfca. Tne rofy drop on the face is of three kinds. Firft, the gutta t'fea hepatica, or the red Class II. i. 4.] OF SENSATION. 527 red pimples on the faces of drunkards, which are probably a kind of crifis, or vicarious inflammation, which fucceeds, or prevents, a torpor of the mem- branes of the liver. This and the fucceeding fpecies properly belong to Clafs IV. 1. 2. 14. Secondly, the pimpled face in conSequence of drink- ing cold water, or eating cold turnips, or other infipid food, when much heated with exercife; which pro- bably arifes from the fympathy between the Skin of the face and the ftomach ; and may be called the gutta rofea fiomatica. Which is diftinguiflied from the former by the habits of the patient in refpea to drinking; by the colour of the eruptions being lefs deep ; and by the patient continuing generally to be troubled with fome degree of apepfia. See Clafs L 3. 1. 3. I knew a lady, who had long been affliaed with pain about the region of the ftomach; and, on drinking half a pint of vinegar, as a medicine, flie had a breaking out commenced on her face; which remained, and fhe became free from the pain about the Stomach. Was this a Stomachic, or an hepatic difeafe ? Thirdly, there is a red face, which confifts of fmaller pimples than thofe above mentioned ; and which is lefs liable to fuppurate ; and which feems to be hereditary, or at leaft lias no apparent caufe like thofe above mentioned ; which may be termed gutta rofea hereditaria, or punaa rofea. Mrs. S. had a pimpled face, which I believe arofe frpm potation of ale. She applied alum in a poultice Y 4 to ^ 32S DISEASES [Class II. i. 4. to it, and had foon a paralytic Stroke, which dif- abled her on one fide, and terminated in her death. Mrs. L. had a red pimpled face, which feemed to have been derived from her mother, who had pro- bably acquired it by vinous potation ; She applied a quack remedy to it, which I believe was a folution of lead, and was feized with epileptic fits, which termi- nated in palfy, and deftroyed her. This fhews the danger of ufing white paint on the face, which is called bifmuth, but is in reality white lead or ceruffa. Mr. Y-----had acquired the gutta rofea on his nofe, and applied a faturnine folution on it for a few nights, and was then feized with paralyfis on one fide of his face; which however he gradually recovered, and has fince acquired the gutta rofea on other parts of his face. Thefe fatal effeas were probably caufed by the dif- agreeable fenfation of an inflamed liver, which ufed before to be relieved by the Sympathetic aaion and confequent inflammation of the ikin of the face, which was now prevented by the ftronger ftimulus of the application of calx of lead. The manner in which difagreeable fenfations induce epilepfy and palfy is treated of in Clafs III. In fome cafes where habitual difcharges, or eruptions, or ulcers are flopped, a torpor of the fyftem may follow, owing to the want of the accuftomed quantity of fenfation or irritation. See Clafs I. 1.2. 9. and II. 1. 5. 6. In both thefe Situations fome other ftimulus Should be ufed to fupply the / Class II. i. 4.] OF SENSATION. 329 the place of that which is taken away; which may either be perpetual, as an iffue; or periodical, as a cathartic repeated once a fortnight or month. Mifs W. an elegant young lady of about twenty, applied a mercurial lotion to her face, which was co- hered with very fmall red points; which feemed to have been not acquired by any known or avoidable means ; flie was feized with inflammation of her liver, and after repeated bleeding and cathartics recovered, and in a few weeks the eruption appeared as before. M. M. Five grains of calomel once a month, with a cathartic, five grains of rhubarb and a quarter of a grain of emetic tartar every night for many weeks. With this preparation mercurial plafters, made with- out turpentine, and applied every night, and taken off every morning, will fometimes fucceed, and may be ufed with fafety. But blistering the face all over the eruption, beginning with a part, fucceeds better than any other means, as I have more than once experien- ced.—Something like this is mentioned in the Letters of Lady Mary Wortley Montague, who bliftered her face with balfam of Mecca. Mrs. F. had for many years had a difagreeably looking eruption on her chin, after a cathartic with calomel, flie was advifed to blifter her whole chin ; on the healing of the blifter a few eruptions again ap^ peared, which ceafed on the application of a fecond blifter. She took rhubarb five grains, and emetic tar- jtar a quarter of a grain every night for many weeks. Mih *v« 350 DISEASES [Class II. i. 4. Mifs L. a young lady about eighteen, had tried variety of advice for pimples over the greateft part of her face in vain. She took the above medicines in- ternally, and bliftered her face by degrees all over and became quite beautiful. A fpot or two now and then appeared, and on this account fhe frequently Slept with parts of her face covered with mercurial plafter, made without turpentine, which was held on by a pafteboard mafk, and taken off in the mornings; if any part of the plafter adhered, a little butter or oil deftroyed the adhefion. 7. Odontitis. Inflammatory tooth-ach is occafioned by inflammation of the membranes of the tooth, or a caries of the bone itfelf. The gum fometimes fuppu- rates, otherwife a fwelling of the cheek fucceeds by affociation, and thus the violence of the pain in the membranes of the tooth is relieved, and frequently cured; and when this happens the difeafe properly belongs to Clafs IV. as it fo far refembles the tranfla- tions of morbid aaions in the gout and rheumatifm. At other times the tooth dies without caries, efpe- cially in people about fixty years of age, or before ; and then it ftimulates its involving membrane, like any other extraneous fubftance. The membrane then be- comes inflamed and thickened, occafioning fome pain, • ana the tooth rifes upwards above the reft, and is gradually puflied out whole and undecaycd ; on its rifing up a pus-like mucus is feen difcharged from the £inn, which furrounds it; and the gmu feems to have left Class II. i. 4-] OF SENSATION. 331 left the tooth, as the fangs or roots of it are in part naked. M. M. Where the tooth is found it can only be faved by evacuations by venefeaion, and a cathartic ; and after its operation two grains of opium, a blifter may alfo be ufed behind the ear, and ether applied to the cheek externally. In flighter cafes two grains of opium with or without as much camphor may be held in the mouth, and fuffered to diffolve near the affeaed tooth, and be gradually fwallowed. See Clafs I. 2. 4. 12. Odontalgia may be distinguished from otitis by the application of cold water to the affeaed tooth ; for as the pain of common tooth-ach is owing to tor- por, whatever decreafes ftimulus adds to the torpor and confequent pain ; whereas the pain of an inflamed tooth being caufed by the increafed aaion of the membranes of it is in fome meafure alleviated bv the application of cold. 8. Otitis. Inflammation and confequent fuppuration of fome membranes of the internal ear frequently occur in children, who fleep in cold rooms, or near a cold wall, without a night-cap. If the bones are affeaed, they come out in a long procefs of time, and the child remains deaf of that ear. But in this cafe there is generally a fever attends this inflam- mation ; and it then belongs to another genus. M. M. A warmer night-cap. Warmifh water fliould be gently iyringed into the ear to keep it clean twice a day ; ami if it dot: not heal in a week, a little 33- DISEASES [Class II. i. 4. a little fpirit of wine fliould be added ; firft about a fourth part, and it fliould be gradually increafed to half reaified fpirit and half water : if it continues long to difcharge matter with a very putrid fmell, the bones are injured, and will in time find their exit, during which time the ear fliould be kept clean by filling it with a weaker mixture of fpirit of wine and water; or a folution of alum in water ; which may be poured into the ear, as the head is inclined, and Shook out again by turning the head, two or three times, morning and evening. See Clafs II. 1. 4. TO. 9. Fiflula lacrymalis. The lacrymal fac, with its punaa lacrymalia and nafal dua, are liable to be de- ftroyed by fuppuration without fever; the tears then run over the eye-lids, and inflame the edges of them, and the cheeks, by their perpetual moifture, and faline acrimony. M. M. By a nice furgical operation a new aperture is to be made from the internal corner of the eye into the noftril, and a filver tube introduced, which fup- plies the defea by admitting the tears to pafs again into the noftril. See Melanges de Chirurgie par M. Pouteau ; who thinks he has improved this operation. 1 o. Fiflula in ano. A mucous difcharge from the anus, called by fome white piles, or matter from a fuppurated pile, has been miftaken for the matter from a concealed fiftula. A bit of cotton wool ap- plied Class II. i. 4.] OF SENSATION. ^Z plied to the fundament to receive the matter, and re- newed twice a day for a week or two, fliould always be ufed before examination with the probe. The probe of an unSkilful empyric fometimes does more harm in the loofe cellular membrane of thefe parts than the original ulcer, by making a fiftula he did not find. The cure of a fiftula in ano of thofe, who have been much addiaed to drinking fpirituous liquor, or who have a tendency to pulmonary confumption, is frequently of dangerous confequence, and is fucceeded by ulcers of the lungs, and death. M. M. Ward's pafte, or twenty black pepper-corns taken after each meal twice a day ; the pepper-corns Should be cut each into two or three pieces. The late Dr. Monro of Edinburgh afferted in his feaures, that he had known a fiftula in ano cured by injeaing firft a mixture of reaified fpirit of wine and water; and by gradually increafing the ftrength of it, till the patient could bear reaified fpirit alone ; by the daily ufe of which at length the fides of the fiftula became callous, and ceafed to difcharge, though the cavity was left. A French furgeon has lately affirmed, that a wire of lead put in at the external opening of the ulcer, and brought through the reaum, and twilled together, will gradually wear itfelf through the gut, and thus effea a cure without much pain. The ends of the leaden wire muft be twilled more and more as it becomes loofe. Or, laftly, it muft be laid open by the knife. 11. Fiflulc Sit DISEASES [Class II. t. 4. ri. Fiftula urethra. Where a ftriaure of the urethra exifts, from whatever caufe, the patient, in forcing the ftream of urine through the ftriaure, dif- tends the urethra behind it; which after a time is liable to burft, and to become perforated ; and fome of the urine is puflied into the cellular membrane, occasioning fiftulas, which fometimes have large fur- faces producing much matter, which is preffed out at the time of making water, and has been miftaken for a catarrh of the bladder; thefe fiftulas fometimes ac- quire an external opening in the perinseum, and part of the urine is difcharged that way. Can this matter be diftinguifhed from mucus of the bladder by the criterion delivered in Clafs II. 1. 6. 6 ? M. M. The perpetual ufe of bougies, either of cat- gut or of coartchouc. The latter may be had at No. 37, Red-lion Street, Holborn, London. The former are eafily made, by moiftening the catgut, and keep- ing it ftretched till dry, and then rounding one end w ith a penknife. The ufe of a warm bath every day for near an hour, at the heat of 94 or 96 degrees, for two or three months, I knew to be uncommonly fuccefsful in one cafe; the extenfive fiftulas com- pletely healing. The patient fliould introduce a bou- gie always before he makes water, and endeavour to make it as fiowly as poifible. See Clafs I. 2. 3. 24. 12. Hepatitis chronica. Chronical inflammation of the liver. A colleaion of matter in the liver has fre- quently been found on dilfeaion, which was not fuf- peaed Class II. i. 4] OF SENSATION. 535 peaed in the living fubjea. Though there may have been no certain figns of fuch a colfeaion of matter, owing to the infenfibility of the internal parts of this vifcus; which has thus neither been attended with pain, nor induced any fever; yet there may be in fome cafes reafon to fufpea the exiftence of fuch an abfcefs ; either from a fenfe of fulnefs in the right hy- pochondre, or from transient pains fometimes felt there, or from pain on preffure, or from lying on the left fide, and fometimes from a degree of fenfitive fever attending it. Dr. Saunders fufpeas the acute hepatitis to exift in the inflammation of the hepatic artery, and the chro- nical one in that of the vena portarum. Treatife on tlie Liver. Robinfon. London. - 13. Scrophula fuppurans. Suppurating fcrophula. The indolent tumors of the lymphatic glands are liable, after a long time, to regain their fenfibility; and then, owing to their former torpor, an increafed aaion of the veffels, beyond what is natural, with inflammation, is the confequence of their new life, and fuppuration fucceeds. This cure of fcrophula generally happens about puberty, when a new energy pervades the whole fyftem^ and unfolds the glands and organs of reproduaion. M. M. See Clafs I. 2. 3. 2r. Where fcrophu- lous ulcers about the neck are difficult to heal, Dr. Beddoes was informed, in Ireland, that an empyric had had fome fuccefs by inflaming them by an ap- plication 3$S DISEASES [Class H. t. 44 plication of wood forrel, oxalis acetofella, the leaves of which are bruifed in a mortar, and applied on the ulcers for two or three days, and then fome more lenient application is ufed. A poor boy, about twelve years old, had a large fcrophulous ulcer on one fide of the cheft beneath the clavicle, and another under his jaw ; he was direaed, about three weeks ago, to procure a pound of dry oak-bark from the tanners, and to reduce it to fine powder, and to add to it one ounce of white lead in fine powder, and to cover the ulcers daily with it, keeping it on by brown paper and a ban- dage. He came to me a few minutes ago, to Shew me that both the ulcers are quite healed. The con- ftant application of linen rags, moistened with a folu- tion of an ounce of fugar of lead in a pint of wa- ter, I think I have feen equally efficacious. 14. Scorbutus fuppurans. In the fea-fcurvy there exifts an inaaivity of venous abforption, whence vibices and petechia?, and fometimes ulcers. As the column of blood prefiing on the origins of the veins of the lower extremities, when the body is erea, oppofes the afcent of the blood in them, they are more frequently liable to become enlarged, and to produce varices, or vibices, or, laftly, ulcers about the legs, than on the upper parts of the body. The expofure to cold is believed to be another caufe of ulcers on the extremities; as happens to many of the poor in winter at Lifbon, who fleep in the open air, 1 without Class II. i.>] OF SENSATION. 337 without ftockings, on the fteps of their churches or palaces. See Clafs I. 2. 1. 15. M. M. A bandage fpread with plafter to cover the whole limb tight. Rags dipped in a folution of fugar of lead. A warm flannel flocking or roller. White lead and oak bark, both in fine powder. Ho- rizontal reft. 14. Schirrus fuppurans. When a fchirrus affeas any gland of no great extent or fenfibility, it is, after a long period of time, liable to fuppurate without in- ducing fever, like the indolent tumors of the conglo- bate or lymphatic glands above mentioned; whence colfeaions of matter are often found after death both in men and other animals; as in the liver of fwine, v/hich have been fed with the grounds of fermented mixtures in the distilleries. Another termination of fchirrus is in cancer, a* defcribed below. See Clafs L 2. 3. 22. 16. Carcinoma. Cancer. When a fchirrous tumor regains its fenfibility by nature, or by any accidental hurt, new veffels fhoot amongft the yet infenfible parts of it, and a new fecretion takes place of a very in- jurious material. This cancerous matter is abforbed, and induces fwelling of the neighbouring lymphatic glands; which alfo become fchirrous, and afterwards cancerous. This cancerous matter does not feem to acquire its malignant or contagious quality, till the cancer be- Z comes 5," DISEASES [Class II. i. 4. comes an open ulcer ; and the matter fecreted in it is thus expofed to the air. Then it evidently becomes contagious, becaufe it not only produces heaic fever, like common matter in ulcers open to the air ; but it alfo, as it becomes abforbed, fwells the lymphatic glands in its vicinity ; as thofe of the axilla, when the open cancer is on the breaft. See Clafs II. 1. 3. Hence exfeaion before the cancer is open is gene- rally a cure ; but after the matter has been expofed to the air, it is feldom of fervice ; as the neighbouring lymphatic glands are already infeaed. I have ob- ferved fome of thefe patients after the operation to have had difeafed livers, which might either have previ- oufly exifted, or have been produced by the fear or anxiety attending the operation. Erofion with arfenic, after the cancer is become an open ulcer, has generally no better effea than exfec- tion, but has been fuccefsful before ulceration. The beft manner of ufing arfenic, is by mixing one grain with a dram of lapis calaminaris, and ftrewing on the cancer fome of the powder every day, till the whole is deftroyed. Cancers on the face are faid to arife from the peri- ofteum, and that unlets this be deftroyed by the knife, or by cauftics, the cancer certainly recurs. After the cancer becomes an open ulcer of fome extent, a puru- lent fever fupervenes, as from other open ulcers, and gradually deftroys the patient. See Clafs II. 1.6. 13. Two very interesting cafes have been.lately pub- lished by Dr. Ewart, of Bath, in which carbonic acid Class II. 1.4.] OF SENSATION. 3}g gas, or fixed air, was kept constantly in contaa with the open cancerous ulcers of the breaft; which then healed like other common ulcers. This is rather to be afcribed to the exclufion of oxygen, than to any fpecific virtue in the carbonic acid. As in common ulcers the matter does not induce heaic fever, till it has been expofed to the air, and then probably united with oxygen. The manner of applying the fixed air, is by in- cluding the cancer in one half or hemifphere of a large bladder ; the edges are made to adhere to the Skin by adhefive plafter, or perhaps a mixture of one part of honey with about twenty parts of carpenter's glue might better fuit fome tender ffdns. The bladder is theri kept constantly filled with carbonic acid gas, by means of a pipe in the neck of it; and the matter let out at a fmall aperture beneath. i 7. Arthrocele. Swelling of the joints feems to have its remote caufe in the foftnefs of the bones, for they could not fwell unlefs they were previoufly foftened, fee Clafs I. 2. 2. 12. The epiphytes, or ends of the bones, being naturally of a loofer texture, are moft liable to this difeafe, and perhaps the cartilages and capfular ligaments may alfo become inflamed and fwelled along with the heads of the bones. This malady is liable to diftort the fingers and knees, and is ufually called gout or rheumatifm; the former of which is .liable to difable the fingers by chalk-Stones, .and thence to have Somewhat a Similar appearance. Z 2 But 34^ DISEASES [Class II. i. 4,. But the arthrocele, or fwelling of the joints, affeas people who have not been intemperate in the ufe of fermented or fpirituous liquors ; or who have not previoufly had a regular gout in their feet ; and in both thefe circumstances differs from the gout. Nor does it accord with the inflammatory rheumatifm, as it is not attended with fever, and becaufe the tumors of the joints never entirely fubfide. The pain or fenfibility, which the bones acquire, when they are inflamed, may be owing to the new veffels, which Shoot in them in their foft ftate, as well as to the diftention of the old ones. . M. M. Flalf a grain of opium twice a day, gra- dually increafed to a grain, but not further, for many months. Thirty grains of powder of bark twice a day for many months. Ten grains of bone-aflies, or calcined hartfliom, twice a day, with decoaion of madder ? Soda phofphorata ? 18. Arihropuofis. Joint-evil. This differs from the former, as that never fuppurates ; thefe ulcers of the joints are generally efteemed to arife from fcrophula ; but as fcrophula is a difeafe of the lymphatic or abforbent fyftem, and this confifts in the fuppuration of the membranes, or glands, or cartilages about the joints, there does not feem a fufficient analogy to authorize their arrangement under the fame name. The white fwelling of the knee, when it fuppurates, comes under this fpecies, with variety of other ulcers attended with carious bones, 19. Carle j Class II. 1.5.] OF SENSATION. 34i 19; Caries offium. A caries of the bones may be termed a fuppuration of them; it differs from the above, as it generally is occafioned by fome external injury, as in decaying teeth ; or by venereal virus, as in nodes on the tibia; or by other matter derived to the bone in malignant fevers; and is not confined to the ends of them. The feparation of the dead bone from the living is a work of fome time. See Sea. XXXIII. 3. i< ORDO I, Increafed Senfation. GENUS V. With the Produclion of new Veffels by external Mem- branes or Glands, without Fever. The ulcers, or eruptions, which are formed on the external Skin, or on the mouth or throat, or on the air-cells of the lungs, or on the inteftines, all of which are more or lefs expofed to the contaa of the atmofpheric air, which we breathe, and which in fome proportion we fwallow with our food and faliva ; or to the contaa of the inflammable air, or hydrogen, which is fet at liberty by the putrefying aliment in the inteftines, or by putrefying matter in large ab- fceffes ; all of them produce contagious matter; which, on being inoculated into the fkin of another perfon, will produce fever^ or a fimilar difeafe. Z 3 In 342 DISEASES [Class II. i. 5. In fome cafes even the matter formed beneath the ikin becomes in fome degree contagious, at leaft fo much fo as to produce fever of the heaic or malignant kind, as foon as it has pierced dirough the ikin, and has thus gained accefs to fome kind of air ; as the frefli pus of a common abfcefs ; or the putrid pus of an abfcefs, which has been long confined ; or of can- cere es ulcers. From this analogy there is reafon to fufpea, that the matter of all contagious difeafes, whether with or without fever, is not infeaious till it has acquired fomething from the air; which, by oxygenating the fecreted matter, may probably produce a new acid. And fecondly, that in heaic fever a part of the purulent matter is abforbed ; or aas on the furface of the ulcer ; as variolous matter affeas the inoculated part of the arm. And that heaic fever is therefore caufed by the matter of an open ulcer ; and not by the fenfation in the ulcer independent of the aerated pus, which lies on it. Which may account for the venereal matter from buboes not giving the infeaion, according to the experiments of the late Mr. Hunter, and for fome other phenomena of contagion. Sec Variola difcreta, Clafs II. 1. 3. 9. SPECIES. 1. Gonorrhoea venerea. A pus-like contagious ma- terial difcharged from the urethra after impure coha- bitation, with fmarting or heat on making water; which begins at the external extremity of the urethra, to Class II. i. 5.] OF SENSATION. 343 to which the contagious matter is applied, and where it has accefs to the air. M. M. In this ftate of the venereal difeafe once Venefeaion, with mild cathartics of fenna and manna, with mucilage, as almond emulfion, and gum arabic, taken for two or three weeks, abfolve the cure. Is camphor of ufe to relieve the ardor urina? ? Do bal- fams increafe or leffen the heat of urine ? Neutral falts certainly increafe the fmarting in making water, by increafing the acrimony of the urine. Can the difcharge from the urethra be foon flopped by Saturnine injeaions, or mercurial ones, or with folution of blue vitriol, at firft very dilute, and gra- dually made ftronger ? And at the fame time left the fyphilis, or general difeafe, fliould fupervene, the patient might take a quarter of a grain of corrofive fublimate of mercury twice a day, as direaed below ? 2. Syphilis. Venereal difeafe. The contagion Shews itfelf in ulcers on the part firft inoculated, as chancres ; ulcers on the tonfils fucceed, with eruption on the fkin, efpecially about the roots of the hair ; after- wards on other parts of the ikin, terminating in dry fcabs; and laftly, with pain and fwelling of the bones. The corona veneris, or crown of Venus, confifts of the eruptions at the roots of the hair appearing moft round the forehead ; which is occafioned by this pai-L being more expofed to the air; which we obferved, at the beginning of this genus, either produces or Z 4 increafes 344 DISEASES [Class II. i. y. increafes the virulence of contagious matter. But it is difficult to conceive from this hiftory, why the throat Should be firft affeaed ; as it cannot be fuppofed, that the difeafe is fo often taken by the faliva, like the fmall-pox, though this may fometimes occur, perhaps very often. The conneaion between the genitals in men and the throat, is treated of in Clafs IV. 1. 2. 7. Hydrophobia. M. M. A quarter of a grain of corrofive fublimate of mercury, taken thrice a day for five or fix weeks, made into a pill with bread-crumbs, or diffolved in a fpoonful of brandy and water, is a very efficacious and almoft certain cure. When it does not fucceed, ic is owing either to the drug being bad, or to its having precipitated from the brandy, or from its being fpoiled in the pill by long keeping. Opium contributes much to expedite the cure both of the fimple gonorrhoea, and of venereal ulcers, by increafing abforption both from the mucous membrane, and from the furface of ulcers. 3. Lepra. Leprofy. Leprofy of the Greeks. The ikin is rough with white branny Shales, which are full of chinks; often moift beneath, and itching. The fcales on the head or arms of fome drinking people are a difeafe of this kind. The perfpirable matter defigned for the purpofe of lubricating the external ikin is fecreted in this difeafe in a too vifcid ftate, owing to the inflammation of the fubcutaneous veffels; and, as the abforbents aa too ftrongly at the fame time, a vifcid Class II. i. 5.] OF SENSATION. 345 vifcid mucus is left adhering to the furface of the ikin. In the leprofy of the Jews, defcribed in the thir- teenth and fourteenth chapters of Leviticus, the de- preffion of the fore beneath the furface of the Skin, and the hairs in it becoming white, feem to have been the principal circumftanccs, which the prieft was direaed to attend to for the purpofe of afcertaining the difeafe. M. M. Effence of antimony from 20 drops to 100 twice or thrice a day, with half a pint of decoaion of elm-bark ; or tinaure of cantharides from 20 to 60 drops four times a day ; or fublimate of mercury, with much diluting find. Acid of vitriol ? Perhaps the cure chiefly depends on much dilution with water, from two to four pints a day, in which elm-bark, or pine-buds, or juniper-tops, may be boiled. Bath or Buxton water drank in large quantities. Warm bath. Oil-Skin bound on the part to confine the perfpirable matter. Ointment of tar and fuet; or poultice for two or three days, and then cerate with lapis calami- naris. Diet of raifins and bread. Abstinence from wine, beer, and all fpirits. 4.. Elephantiafis. Leprofy of the Arabs. A con- tagious difeafe ; the Skin is thickened, wrinkled, rough, unauous, deftitute of hair, without any fenfation of touch in the extremities of the limbs ; the face de- formed with tubercles ; the voice hoarfe, and with a nafal tone. Cullen. 5. Framboefia. 346 DISEASES [Class II. i. £. 5. Tramboc/ia* Yaws is -raid to be contagious and hereditary. It principally aifeas the negroes in the Weft Indies. Edinb. Eflays, Vol. VI. 6. Pfory. IlCh. A contagious prurient eruption. There are two kinds of itch, that which appears between the "fingers, and under the joints of the knees and elbows ; and that which feldom is feen in thefe places, but all over the other parts of the body. The latter is feldom thought to be the itch, as it does not eafily infea eyen a bedfellow, and refills the ufual means of cure by brimftone. If the itch be cured too haftily by rubbing mercu- rial or arfenical preparations over the whole body, or on too great a part of it, many bad fymptoms are produced; as weaknefs of digeftion, with pale bloated countenance, and tendency to dropfy. I have twice feen St. Vitus's dance occur from the ufe of a mercurial girdle; and once a fwelled liver. I have alfo feen a fwelled fpleen and fwelled legs from the external ufe of arfenic in the cure of the itch. And very numerous and large phlegmons commonly fucceed the too hafty cure of it by other means. There does not appear a ftria analogy between the hafty cure of the heh, and the retrocession of the puftules is the fecondary fever of the fmall-pox ; be- caufe in that the ahforption of the matter is evinced by the fwelling of the face and hands, as the puftules recede, as explained in Clafs II. 1. 3. 9. Variola difcreta. And a fever is produced by this abforption ; neither of which happen, when the puftules of the itch are deftroyed by mercury or arfenic. Nor Class II. i. $.] - OF SENSATION. 347 Nor can thefe inconveniencies, which occur on the too hafty cure of the itch, he explained by thofe which follow the cure of fome kinds of gutta rofea, Clafs II. i. 4. 6. as in thofe the eruptions on the face were an affociated difeafe with inflammation of the liver or ftomach, which they were accuftomed to relieve; whereas the itch is not known to have had any pre- vious catenation with other difeafes. In the itch there exifts not only great irritation in the produaion of the puftules, but great fenfation is caufed by their acrimony afterwards; infomuch that the pain of itchier, without the interrupted fmarting occafioned by fcratching, would be intolerable. This great excitement of the two fenforial powers of irri- tation and fenfation is fo great, when the puftules are diffufed over the whole furface of the body, that a torpor Succeeds the fudden ceafing of it; which affeas thofe parts of the fyftem, which were moft catenated with the new motions of the fkin, as the ftomach, whence Indigeftion and flatulency ; or which are ge- nerally moft liable to fall into torpor, as the numerous glands, which form the liver. Whence the difeafes confequent to the hafty cure of the itch are difeafes ©f debility, as tumid vifcera, cedematous fwellings, and St. Vitus's dance, which is a debility of affocia- tion. In the fame manner indigeftion, with green evacuations, are faid to follow an injudicious applica- tion of ceruffa to Stop too haftily the exfudation behind the ears of children, Clafs I. 1.2. 9. And dropfies are liable to fucceed the cure of old ulcers of the legs, which have long ftimulated the fyftem. M.M. 5*« DISEASES [Class II. i. £ M. M. The fize of a large pea, of an ointment confifting of one part of white precipitate of mercury to fix parts of hogs' lard well triturated together, t6 be rubbed on a part of the body every night, and waffled off with foap and water next morning, till every part is cleared ; with lac fulphuris twenty grains to be. taken every morning inwardly. Warm faline bath, with white vitriol in it. Flowers of fulphur mixed with thick gruel, with hogs fat. With either of which the body may be Smeared all over. 7. Pfora ebriorum. Elderly people, who have been much addiaed to fpirituous drinks, as beer, wine, or alcohol, are liable to an eruption all over their bodies ; which is attended with very affliaing itching, and which they probably propagate from one part of their'bodies to another with their own nails by fcratch- ing themfelves. I faw fatal effeas in one fuch patient by a too extenfive ufe of a folution of lead; the eruption disappeared, he became dropfical, and died; . I fuppofe from the too fuddenly ceafing of the great ftimulus caufed by the eruptions over the whole Skin, us in the preceding article. M. M. The patient fliould gradually accuftom him- felf to half his ufual quantity of vinous potation. The warm bath, with one pound of fait to every three gallons. Mercurial ointments on fmall parts of the Skin at a time. A grain of opium at night inftead of the ufual potation of wine or beer. 8. Herpes. Class II. i. 5.] OF SENSATION. 349 8. Herpes. Herpes confifts of gregarious fpreading excoriations, which are fucceeded by branny fcales or fcabs. In this difeafe there appears to be a deficient abforption of the Subcutaneous mucus, as well as in- flammation and increafed fecretion of it. For the fluid not only excoriates the parts in its vicinity by its acri- mony, but is very faline to the tafte, as fome of thefe patients have affured me ; I believe this kind of eruption, as well as the tinea, and perhaps all other cutaneous eruption, is liable to be inoculated in other parts of the body by the finger-nails of the patients in fcratching themfelves. It is liable to affea the hands, and to return at diftant periods ; and is probably a fecondary difeafe as well as the zona ignea, or Shingles, defcribed below. M. M. Poultice the eruption with bread and milk, or raw carrots grated, for two or three whole days, to dilute or receive the difcharged fluid, and abate the inflammation ; then cover the parts with frefh cerate mixed with lapis calaminaris. On the parts not ex- coriated mercurial ointment, made of one part of white calx of mercury and fix of hogs' fat. Internally, after venefeaion, gentle repeated cathartics. Laftly* ti'-.c bark. Acid of vitriol. Bolus Armenia?, or teftacia. Antimonials. Decoaion of interior bark of elm. 9. Zona ignea. Shingles. This eruption has been thought a fpecies of herpes by fome writers, and by others a fpecies of eryfipelas. Yellow or livid veficles appear, 35* DISEASES [Class II. i. 5. appear, producing a corrofive ichor, which is fome- times attended with a degree of fever. It is faid to infeft fometimes the thorax and ribs, but its moft general fituation is on the fmall of the back, over one kidney, extending forward over the courfe of one of the ureters. There is reafon to fufpea, that this alfo is a fecon- dary or fympathetic difeafe, as well as the preceding one ; but future obfervations are required, before it can be removed to the fourth clafs, or difeafes of af- fociation. In three patients I have been induced to be- lieve, that the eruption on the loins was a tranflation of inflammation from the external membrane of the kidney to the Skin. They had, for a day or two before the appearance of the eruption, complained of a dull pain on the region of one kidney, but without vomiting ; by which it was diftinguiflied from nephritis interna, or gravel; and without pain down the out- fide of the thigh, by-which it was diftinguifhed from fciatica. In other fituations the Shingles may fympathize with other internal membranes, as in a cafe published by Dr. Ruffel (De Tabe Glandulari), where the retroceflion of the Shingles was fucceeded by a ferious »:yfpncea. M. M. Venefeaion, if the pulfe is ftrong. Calomel three or four grains, very mild repeated cathartics. Poultice for a few days, then cerate of lapis calami- naris, as in herpes. A grain of emetic tartar diffolved in a pint of water, and taken fo as to empty the fto- mach and inteftines, is faid much to haften the cure; compreffes Class II. i. 5.] OF SENSATION. 35I compreffes foaked in a Saturnine folution are recom- mended externally on the eruption ; and cerate where there are ulcerations. Defr.net's Surgical Journal, Vol, II. p. 378. If this be a vicarious difeafe, it fliould continue half a lunation ; left, on its ceafing, the bad habits of motion of the primary difeafe fliould not have been fo perfeaiy diffevcred, but that they may recur. 10. Annulus repens. Ring-warm. A prurient erup- tion formed in a circle, affeaing children, and would feem to be the work of infeas, according to the theory of Linna?us, who afcribes the itch and dyfentery to microfcopic anlmalcula. Thefe animalcula are pro- bably the effea, and not the caufe, of thefe eruptions; as they are to be feen in all putrefcent an inn! fluids. The annular propagation of the rirg-worm, and its continuing to enlarge its periphery, is well accounted for by the acrimony of the ichor or faline fluid erod- ing the Skin in its vicinity. M. M. Cover the eruption daily with ink. With white mercurial ointment, as defcribed above hi herpes. With folution of white vitriol ten grains to an ounce, Thefe metallic calces Stimulate the abfor- bents into ftronger aaion, whence the fluid has h:; faline part re-abforbed, and that before it lias accef, to the air, which probably adds to its acrimony by oxygenating it, and thus producing a new acid. 11. Tinea. Scald head. This contagious eruption affeas the roots of the hair, and is generally ,moit 2 viruJcnt 35* DISEASES [Class II. i. j. virulent around the edges of the hair on the back part of the head ; as the corona veneris appears moft on the edges of the hair on the forepart of the head ; for in thefe parts the eruption about the roots of the hair is moft expofed to the external air, by which its acrimony or noxious quality is increafed. The abforption of the matter thus oxygenated fwells the lymphatics of the neck by its ftimulus, oc- casioning many little hard lumps beneath the feat of the eruption : when this happens, the fooner it is cured the better, left the larger lymphatics of the neck fhould become affeaed. M. M. The art of curing thefe eruptions confifts, firft, in abating the inflammation, and confequent fecretion of a noxious material. Secondly, to prevent its accefs to the air, which fo much increafes its acri- mony. And thirdly, to promote the abforption of it, before it has been expofed to the air ; for thefe pur- pofes venefeaion once, and gentle cathartics, which promote abforption by emptying the blood-veffels. Next poultices and fomentations, with warm water, abate inflammation by diluting the faline acrimony of the fecreted fluid, and abating the painful fenfation. Afterwards cerate joined with fome metallic calx, as of zinc or lead, or folution of lead, mercury, or copper, or iron, which may ftimulate the abforbent fyftem into ftronger aaion. Cover the Shaved head with tar and fuet, and a bladder; this, by keeping the air from the fecreted fluid, much contributes to its mildnefs, and the ftimulus of Class II. i. 5.] OF SENSATION. 353 of the tar increafes its abforption. See the three pre- ceding fpecies of this genus. 12. Crufia laclea. Milk-cruft is a milder difeafe than tinea, affeaing the face as well as the hairy fcalp of very young children. It is not infeaious, nor liable to fwell the lymphatics in its vicinity like the tinea. M. M. Cover the eruption with cerate made with lapis calaminaris, to be renewed every day. Mix one grain of emetic tartar with forty grains of chalk, and divide into eight papers, one to be taken twice a day, or with magnefia alba, if ftools are wanted. The child fhould be kept cool and much in the air. 13. Trichoma. Plica polonica. A contagious dif- eafe, in which the hair is faid to become alive and bleed, forming inextricable knots or plaits of great length, like the fabled head of Medufa, with intole- rable pain, fo as to confine the fufferer on his bed for vears. A a ORDO 35** DISEASES [Class II. i. fig, ORDO I. Increafed Senfation. GENUS VI. With Fever confequent to the Produclion of new VefjeU or Fluids. SPECIES. i. Febris fenfitiva. Senfitive fever, when unmixed with either irritative or inirritative fever, may be dif- tinguiflied from either of them by the lefs comparative diminution of mufcular ftrength; or in other words, from its being attended with lefs diminution of the fenforial power of irritation. An example of unmixed fenfitive fever may generally be taken from the pulmo- nary confumption ; in this difeafe patients are feen to walk about with eafe, and to do all the common offices of life for weeks, and even months, with a pulfe of 120 ftrokes in a minute; while in, other fevers, whether irritated ©r inirritated, with a pulfe of this frequency, the patient generally lies upon the bed, and exerts no mufcular efforts without difficulty. The caufe of this curious phenomenon is thus to be understood; in the fenfitive fever a new fenforial power, viz. that of fenfation, is fuperadded to that of irritation ; which in other fevers alone carries on the increafed circulation. Whence the power of irritation is not much more exhaufted than in health ; and thofe mufcular motions, which are produced in confequence of Class II. i. 6.] OF SENSATION. 35* of it, as thofe which are exerted in keeping the body upright in walking, riding, and in the performance of many cuftomary aaions, are little impaired. For an account of the irritated fenfitive fever, fee Clafs IL 1.2. i. ; for the inirritated fenfitive fever, Clafs II. i. 3. 1. IV. 2. 4. 11. ■ 2. Febris a pure claufo. Fever from inclofed matter is generally of the irritated fenfitive kind, and con- tinues for many weeks, and even months, after the abfcefs is formed ; but is diftinguiflied from the fever from aerated matter in open ulcers, becaufe there are feldom any night-fwcats, or colliquative diarrhcea in this, as in the latter. The pulfe is alfo harder, and requires occafional venefeaion, and cathartics, to abate the inflammatory fever ; which is - liable to increafe again every three or four days, till at length, unlets the matter has an exit, it deftroys the patient. In this fever the matter, not having been expofed to the air, has not acquired oxygenation ; in which a new acid, or fome other noxious property, is produced; which aas like contagion on the conftitution inducing fever-iits, called heaic fever, which terminate with fweats or diarrhcea; whereas the matter in the clofed abfcefs is either not abforbed, or does not fo affea the circulation as to produce diurnal or heaic fever-fits ; but the ftimulus of the abfcefs excites fo much fenfa- tion as to induce perpetual pyrexia, or inflammatory fever, without fuch marked remiffions. Nevertheless there fometimes is no fever produced, when the mat- A a 2 . ter 3S« DISEASES [Class II. i. tf, ter is lodged in a part of little fenfibility, as in the Kver; yet a white pus-like fediment in thofe cafes exifts I believe generally in the urine, with occasional wandering pains about the region of the liver or cheft. 3, Vomica. An abfcefs in the lungs is fometimes • produced after peripneumony, the cough and fliortnefs of breath continue in lefs degree, with difficulty in lying on the well fide, and with fenfitive irritated fever, as explained in the preceding article. The occasional increafe of fever, with hard pulfe and fizy blood, in thefe patients, is probably owing to the inflammation of the walls of the vomica; as it is attended with difficulty of breathing, and requires ve- nefeaion. Mr. B-----, a child about feven years old> lived about five weeks in this fituation, with a pulfe from 150 to 170 in a minute, without fweats, or diar- rhcea, or fediment in his water, except mucus occa- fionally ; and took fufficient nourishment during the whole time. The blood taken was always covered with a ftrong cupped fize, and on his death three or four pints of matter were found in one fide of the cheft ; which had probably, but lately, been effufed from a vomica. This child was frequently induced to fwing, both in a reciprocating and in a rotatory Swing, without any apparent abforption of matter; in both thefe fwings he expreffed pleafure, and did not appear to be vertiginous. M. M. Repeated emetics. Digitalis ? Perfeverance in rotatory Swinging, See Clafs II. 1. 6. 7. Mr. Class II. i. 6.] OF SENSATION. 35J Mr. I. had laboured fome months under a vomica after a peripneumony, he was at length taken with a catarrh, which was in fome degree endemic in March 1795, which occafioned him to fneeze much, during which a copious haemorrhage from the lungs occurred, and he fpit up at the fame time half a pint of very fetid matter, and recovered. Hence errhines may be occafionally ufed with advantage. 4. Empyema. When the matter from an abfcefs in the lungs finds its way into the cavity of the cheft, it is called an empyema. A fervant man, after a violent peripneumony, was feized with fymptoms of empyema, and it was determined, after fome time, to perform the operation; this was explained to him, and the ufual means were employed by his friends to encou- rage him, " by advifing him not to be afraid.'* By which good advice he conceived fo much fear, that he ran away early next morning, and returned in about a week quite well. Did the great fear promote the ab- forption of the matter, like the ficknefs occafioned by digitalis ? Fear renders the external Skin pale ; by this continued decreafe of the aaion of the abforbents of the Skin might not thofe of the lungs be excited into greater aaivity ? and thus produce increafed pulmonary abforption by reverfe fympathy, as it produces pale urine, and even ftools, by direa fympathy ? M. M. Digitalis ? 5. Febris Mefenterica. Fever from matter formed in the mefentery is probably more frequent than is A a 3 fufpc&ed. 358 DISEASES [Class II. 1.6. fufpeaed. It commences with pain in the bowels, with irritated fenfitive fever; and continues many weeks, and even months, requiring occasional venefec- tion, and mild cathartics; till at length the continu- ance of the pyrexia, or inflammatory fever, deftroys the patient. This is an affeaion of the lymphatic glands, and properly belongs to fcrophula; but as the matter is not expofed to the air, no heaic fever, pro- perly fo called, is induced, 6. Febris a pure aerato. Fever from aerated mat- ter. A great colfeaion of matter often continues a Jong time, and is fometimes totally abforbed, even from venereal buboes, without producing any diforder in the arterial fyftem. At length, if it becomes pu- trid by its delay, and one part of the matter thus .becomes aerated by the air given out by the other part; or if the ulcer has been opened, fo that any part of it has been expofed to the air for but one day, a heaic fever is produced. Whence the utility arifes of opening large abfeeffes by fetons, as in that cafe little or no heaic fever is induced ; becaufe the mat- ter is fqueezed out by the fide of the Spongy threads of cotton, and little or no air is admitted ; or by tap- ping the abfcefs with a trocar, as mentioned in ifchias, Clafs II. 1. 2. 18. In this fever the pulfe is about 120 in a minute, and its accefs is generally in an evening, and fome- times about noon alfo, with fweats or purging to- wards morning, or urine with pus-like fediment; and the patients bear this fever better than any othe* with Class II. i. 6.] OF SENSATION. 3-59 with fo quick a pulfe; and laftly, when all the matter from a concealed ulcer is abforbed, or when an open ulcer is healed, the heaic fever ceafes. Here the ab- forbed matter is fuppofed to produce the fever, and the diarrhcea, fweats, or copious muddy urine, to be fimply the confequence of increafed fecretion, and not to confift of the purulent matter, which was fuppofed to be abforbed from the ulcer. See Sudor calidus, Clafs I. 1.2. 3. The aaion of the air on ulcers, as we have already Shewn, increafes the acrimony of the purulent matter, and even converts it into a weaker kind of contagious matter; that is, to a material inducing fever. This was afcribed to the union of the azotic part of the atmofphere with the effufed pus in Sea. XXVIII. 2. but by contemplating more numerous faas and ana- logies, I am now induced to believe, that it is by the union of oxygen 'with it ; firft, becaufe oxygen fo greedily unites with other animal fubftances, as the blood, that it will pafs through a moift bladder to combine with it, according to the experiment of Dr. Prieftley. Secondly, becaufe the poifons of venomous creatures are fuppofed to be acids of different kinds, and are probably formed by the contaa of air after their fecretion. And laftly, becaufe the contagious matter from other ulcers, as in itch, or fmall-pox, are formed on external membranes, and are probably combinations of animal matter and oxygen, producing other new acids; but further experiments muft deter- mine this queftion. A a 4 It $6* DISEASES [Class II. i. 6. It was thought a fubjea of confequence by the JEfculapian Society at Edinburgh, to find a criterion which fhould diftinguifh pus from mucus, for the pur- pofe of more certainly difcovering the pretence of ulcers in pulmonary difeafes, or in the urinary paf- fages. For this purpofe that foeiety offered their firft; gold medal, which was conferred on the late Mr. Charles Darwin, in the year 1778, for his experiments on this fubjea. From which he deduces the follow- ing conclusions : " 1. Pus and mucus are both foluble in the vitri- olic acid, though in very different proportions, pus being much the lefs foluble. " 2. The addition of water to either of thefe com- pounds decompofes it; the mucus thus feparated, either fwims on the mixture, or forms large flocci in it; whereas the pus falls to the bottom, and forms on agitation a uniform turbid mixture. " 3. Pus is diffufible through a diluted vitriolic acid, though mucus is not; the fame occurs with water, or a folution of fea fait. " 4. Nitrous acid diffolves both pus and mucus; water added to the folution of pus produces a pre- cipitate ; and the fluid above becomes clear and green; while water and the folution of mucus form a dirty coloured fluid. "5. Alkaline lixivium diffolves (though fometimes with difficulty) mucus, and generally pus. " 6. Water precipitates pus from fuch a folution, but does not mucus. ' 7. " Where Class II. i. 6.] OF SENSATION 36t " 7. Where alkaline lixivium does not diffolve pus, it ftill diftinguifhes it from mucus; as it then prevents its diffufion through water. " 8. Coagulable lymph is neither foluble in diluted nor concentrated vitriolic acid. "9. Water produces no change on a folution of fo- rum in alkaline lixivium, until after long Standing, and then only a very flight fediment appears. "10. Corrofive fublimate coagulates mucus, but does not pus. " From the above experiments it appears, that Strong Vitriolic acid and water, diluted vitriolic acid, and cauftic alkaline lixivium and water will ferve to dif- tinguifh pus from mucus; that the vitriolic acid can feparate it from coagulable lymph, and alkaline lix- ivium from ferum. " And hence, when a perfon has any expeaorated material, the compofition of which he wiflies to afcer- tain, let him diffolve it in vitriolic acid, and in cauftic alkaline lixivium; and then add pure water to both folutions: and if there is a fair precipitation in each, he may be affured that fome pus is prefent. If in neither a precipitation occurs, it is a certain teft, that the material is entirely mucus. If the material cannot be made to diffolve in alkaline lixivium by time and trituration, we have alfo reafon to believe that it is pus." Experiments on Pus and Mucus. Cadell. London. 7. Phthifis pulmonalis. In pulmonary confumption the fever is generally fuppofed to be the confequence of 3^2 DISEASES [Class II. i. & of the ftimulus of abforbed matter circulating in the blood-veffels, and not fimply of its ftimulus on their extremities in the furface of the ulcers; as mentioned in Clafs II. 1.5. and Clafs II. 1. 3. 9. The ulcers arc probably fometimes occafioned by the putrid acrimony of effufed blood remaining in the air-cells of the lungs after an hcemoptoe. See Clafs I. 2. 1. 9. The remote caufe of confumption is ingenioufly aferibed by Dr. Beddoes to the hyper-oxygenation of the blood, as mentioned Seaion XXVIII. 2. As the patients liable to confumption are of the inirritabfe temperament, as appears by the large pupils of their eyes; there is reafon to believe, that the hcemoptoe is immediately occafioned by the deficient abforption of the blood at the extremities of the bronchial vein ; and that one difficulty of healing the ulcers is occafioned by the deficient abforption of the fluids effufed into them. See Sea. XXX. 1. and 2. The difficulty of healing pulmonary ulcers may be owing, as its remote caufe, to the inceffant motion of alf the parts of the lungs; whence no fcab, or indu- rated mucus, can be formed fo as to adhere on them. Whence thefe naked ulcers are perpetually expofed to the aaion of the air on their furfaces, converting their mtld purulent matter into a contagious ichor ; which not only prevents them from healing, but by its aaion on their circumferences, like the matter of itch or tinea, contributes to fpread them wider. See the preceding article and Sea. XXXIII. 2. 7. where the pulmonary phthuis is fuppofed to be infeaious. This Class II. i. 6.] OF SENSATION. ■/,$ This acidifying principle is found in all the metallic calces, as in lapis calaminaris, which is a calciform ore of zinc ; and in ceruffa, which is a. calx of lead; two materials which are powerful in healing excoria- tions, and ulcers in a Short time by their external application. How then does it happen, that the oxygen in the atmofphere fliould prevent pulmonary ulcers from healing, and even induce them to Spread wider; and yet in its combination with metals, it fliould facilitate their healing ? The healing of ulcers confifts in promoting the abforption of the fluids effufed into them, as treated of in Seaion XXXIII. 3. 2. Oxygen in combination with metals, when applied in certain quantity, produces this effea by its ftimulus; and the metallic oxydes not being decompofed by their contaa with animal matter, no new acid, or contagious material, is produced. So that the combined oxygen, when applied to an ulcer, fimply 1 fuppofe promotes abforption in it, like the application of other materials of the articles forbentia or ineitantia, if applied exter- nally ; as opium, bark, alum. But in the pulmonary ulcers, which cannot protea themfelves from the air by forming a fcab, the uncombined oxygen of the atmofphere unites with the purulent matter, converting it into a contagious ichor ; which by infeaion, not by \ erofion, enlarges the ulcers, as in the itch or tinea ; which might hence, according to Dr. Beddoes's inge- nious theory of confumption, be induced to heal, if expofed to an atmofphere deprived of a part of it.^ oxygen. This I hope future experiments will confirm, and 3&4 DISEASES [Class II. 1. 6i and that the pneumatic medicine will alleviate the evils of mankind in many other, as well as in this moft fatal malady. M. M. Firft, the refpiration of air lowered by an additional quantity of azote, or mixed with fome »proportion of hydrogen, or of carbonic acid air, may be tried ; as defcribed in a late publication of Dr. Beddoes on the medicinal ufe of faaitious am*. John- fan, London. Or laftly, by breathing a mixture of one tenth part of hydro-carbonate mixed with common air, according to the difcovery of Mr. Watt, which has a double advantage in thefe cafes, of diluting the oxygen of ,the atmofpheric air, and inducing ficknefs, which increafes pulmonary abforption, as mentioned below. An atmofphere diluted with fixed air fcar- bonic acid) might be readily procured by fetting tubs of new wort, or fermenting beer, in the parlour and lodging-room of the patient. For it is not acids floating in the air, but the oxygen or acidifying'prin- ciple, which injures or enlarges pulmonary ulcers by combining with the purulent matter. Another eafy method of adding carbonic acid gas to the air of a room, would be by means of an appa- ratus invented by Mr. Watt, and fold by' Bolton and Watt at Birmingham, as defcribed in Dr. Beddoes' Treatife on Pneumatic Medicine. Johnfon, London. It confifts of an iron pot, with an arm projeaing, and a method of letting water drop by flow degrees on chalk, which is to be put into the iron pot, and expofed to a moderate degree of heat over a com- mon Class II. i. 6.] OF SENSATION. 3$5 mon fire. By occafionally adding more and more chalk, carbonic acid gas might be carried through a tin pipe from the arm of the iron pot to any part of the room near the patient, or from an adjoining room. In the fame manner a diffufion of folution of flowers of zinc might be produced and breathed by the patient, and would be likely much to contribute to the healing of pulmonary ulcers; as obferved by Mr. Watt. See the treatife above mentioned. Breathing over the vapour of cauftic volatile alkali might eafily be managed for many hours in a day ; -which might neutralize the acid poifon formed on pulmonary ulcers by the contaa of oxygen, and thus prevent its deleterious quality, as other acids become fefs cauftic, when they are formed into neutral falts with alkalis. The volatile fait fliould be put into a tin canifter, with two pipes like horns from the top of it, one to fuck the air from, and the other to admit it. Secondly, the external ulcers in fcrophulous habits are pale and flabby, and naturally difinclined to heal, the depofition of fluids in them being greater than the abforption ; thefe ulcers have their appearance immediately changed by the external application of metallic calxes, and the medicines of the article Sor- bentia, fuch as ceruffa and the bark in fine powder, fee Clafs I. 2. 3. 21. and are generally healed in a fhort time by thefe means. Induced by thefe obfer- vations, I wifhed to try the external application of fuch powders to ulcers in the lungs, and conftru&ed a box 366 DISEASES [Class XI. i. & a box with a circulating bruffi in it, as defcribed in the annexed plate ; into this box two ounces of fine powder of Peruvian bark were put, and two drams of ceruffa in fine powder; on whirling the central bruffi, part of this was raifed into a cloud of powder, and the patient, applying his mouth to one of the tin pipes rifing out of the box, inhaled this powder twice a day into his lungs. I obferved it did not produce any cough or uneafinefs. This patient was in the laft ftage of confumption, and was foon tired of the experiment, nor have I had fuch patients as I wifhed for the repetition of it. Perhaps a fine powder of manganefe, or of the flowers of zinc, or of lapis calaminaris, might be thus applied to ulcers of the lungs with greater advantage ? Perhaps air impreg- nated with flowers of zinc in their moft comminuted ftate, might be a better way of applying this powder to the lungs, as difcovered by Mr. Watt. See Dr. Beddoes on Pneumatic Medicine. Johnfon. Thirdly, as the healing of an ulcer confifts in pro- ducing a tendency to abforption on its furface greater than the depofition on it; fee Sea. XXXIII. 3. 2. other modes of increafing pulmonary abforption, which are perhaps more manageable than the preceding ones, may be had recourfe to ; fuch as by producing frequent naufea or ficknefs. fee Sea. XXIX. 5. 1. and Art. IV. 2. The great and fudden abforption of fluid from the lungs in the anafarca pulmonum by the ficknefs induced by the exhibition of digitalis, aftonifhes thofe who have not before attended to it, by Class II. 1.6.3 OF SENSATION. 3:7 by emptying the fwelled limbs, and removing the difficulty of breathing in a few hours. The moft manageable method of ufing digitalis is by making a faturated tinaure of it, by infufing two ounces of the pov/der of the leaves in a mixture of four ounces of reaified fpirit of wine, and four ounces of water. Of this from 30 to 60 drops, or upwards, from a two-ounce phial, are to be taken twice in the morning part of the day, and to be fo managed as not to induce violent ficknefs. If ficknefs neverthelefs comes on, the patient muft for a day or two omit the medicine; and then begin it again in reduced dofes. Mr.----, a young man about twenty, with dark eyes, and large pupils, who had every fymptom of pulmonary ulcers, I believed to have been cured by digitalis, and pubjifhed the cafe in the Tranfaaions of the College, Vol. III. But about two years afterwards I heard that he relapfed and died. Mr. L----, a corpulent man, who had for fome weeks laboured under a cough with great expeaoration, with quick pulfe, and difficulty of breathing, foon recovered by the ufe of digitalis taken twice a day ; and though this cafe might probably be a peripneumonia notha, or catarrh, it is here related as Shewing the power of pulmonary abforption excited by the ufe of this drug. Another method of inducing ficknefs, and pulmo- nary abforption in confequence, is by failing on the iea ; bv which many confumptive patients have been laid S6« DISEASES [Class II. 1.6. faid to have received their cure; which has been crroneoufly aferibed to fea-air, inftead of fea-ficknefs ; whence many have been fent to breathe the fea-air on the coafts, who might have done better in higher Situations, where the air probably contains lefs oxygen gas, which is the heavieft part of it. See a Letter from Dr. T. C. below. A third method of inducing ficknefs, and confe- quent pulmonary abforption, is by the vertigo occa- fioned by twinging ; which has lately been introduced into praaice by Dr. Smith, (Effay on Pulmonary Confumption), who obferved that by fwinging the heaic pulfe became flower, which is explained in Clafs IV. 2. i. 10. The ufual way of reciprocating fwinging, like the ofcillations of a pendulum, pro- duces a degree of vertigo in thofe, who are unufed to it; but to give it greater effea, the patient fhould be placed in a chair fufpended from the ceiling by two parallel cords in contaa with each other, the chair fliould then be forcibly revolved 20 or 40 times one way, and fuffered to return fpontaneoufly ; which induces a degree of ficknefs in moft adult people, and is well worthy an exaa and pertinacious trial, for an hour or two, three or four times a day for a month. The common means of promoting abforption in ulcers, and of thickening the matter in confequence, by taking the bark and opium internally, or by metallic falts, as of mercury, fteel, zinc, and copper, in fmall quantities, have been repeatedly ufed in pulmonary 4 confumption; Class II. i. 6.J OF SENSATION. 359 confumption ; and may have relieved fome of the fymptoms. As mercury cures venereal ulcers, and as pulmonary ulcers refemble them in their not having a difpofition to heal, and in their tendency to enlarge themfelves, there were hopes, from analogy, that It might have fucceeded. Would a folution of gold in aqua regia be worth trying ? When vinegar is applied to the lips, it renders them inftantly pale, by pro- moting the venous abforption ; if the whole fkin was moiftened with warmifli vinegar, would this promote Venous abforprion in the lungs by their fympathy uith the ikin ? The very abstemious diet on milk and ve- getables alone is frequently injurious. FleSh-meat once a day, with fmall wine and water, or fmall beer, is preferable. Half a grain of opium twice a day, or a grain, I believe to be of great ufe at the commence- ment of the difeafe, as appears from the fubfequent cafe. Mifs-----, a delicate young lady, of a confumptive family, when flie was about eighteen, had frequent cough, with quick pulfe, a pain other fide, and the general appearances of a beginning confumption. She took about five drops of laudanum twice a day in a faline draught, which was increafed gradually to ten. In a few weeks flie recovered, was afterwards mar- ried, bore three or four children, and then became confiunptive and died. The following cafe of hereditary confumption is re- lated by a phyfician of great ability and very extenfive practice ; and, as it is his own cafe, abounds with B b much ST DISEASES Class II. i. 6.3 much nice obfervation and ufeful knowledge ; and. as it has been attended with a favourable event, may give confolation to many, who are in a fimilar fitua- tion ; and fliews that Sydenham's lecommendation of riding as a cure for confumption is not fo totally mef- feaual, as is now commonly believed. " J. C. aged 27, with black hair, and a ruddy complexion, was fubjea to cough from the age of pu- berty, and occasionally to fpitting of blood. His ma- ternal grandfather died of confumption under thirty years of age, and his mother fell a viaim to this dif- eafe, with which flie had long been threatened, in her 43d year, and immediately after flie ceafed to have children. In the fevere winter of 1783-4, he was much affliaed with cough; and being expofed to in- tenfe cold, in the month of February he was feized 'with peripneumony. The difeafe was violent and dangerous, and after repeated bleedings as well r<^ bufferings, which he fupported with difficulty, in about fix weeks he was able to leave his bed. At this time the cough was fevere, and the expectoration difficult. A fixed pain remained on the left fide, where an iffue was inferted ; regular heaic came on every day about an hour after noon, and every night heat and reftieffnefs took place, fucceeded toward*, morning by general perfpiration. " The patient, having formerly been fubjea to ague, was Struck with the refemblanee of the febrile parox- yfm, v/ith what he had experienced under that difeafe, and was willing to flatter himfelf it might be of the fame Class II. 1.6.] OF SENSATION. £7! fame nature. He therefore took bark in the interval of fever, but with an increafe of his cough, and this requiring venefeaion, the blood was found highly in- flammatory. The vaft quantity of blood which he had loft from time to time, produced a difpofition to fainting, when he refumed the upright pofture, and he was therefore obliged to remain almoft constantly in a recumbent pofition. Attempting to ride out in a- carriage, he was furprifed to find that he could fit up- right for a confiderable time, while in motion, without inconvenience, though, on ftopping the carriage, the difpofition to fainting returned. " At this time, having prolonged his ride beyond the ufual length, he one day got into an uneven road at the ufual periocl of the recurrence of the heaic pa- roxyfms, and that day he miffed it altogether. This* circumftance led him to ride out daily in a carriage at the time the febrile acceffion might be expeaed, and fometimes by this means it was prevented, fometimes deferred, and almoft always mitigated. " This experience determined him to undertake a journey of fome length, and Briftol being, as is ufual in fuch cafes, recommended, he fet out on the 19th of April, and arrived there on the 2d of May. During the greater part of this journey (of 175 miles) his cough was fevere, and being obliged to be bled three different times on the road, he was no longer able to fit upright, but at very Short intervals, and was obliged to lie at length in the diagonal of a coach. The heaic paroxyfms were not interrupted during the B 2 journey, 37* DISEASES [Class II. i. 6. journey, but they were irregular and indiftina, and the falutary effeas of exercife, or rather of geftation, were impreffed on the patient's mind. " At Briftol he flayed a month, but reaped no bene- fit. The weather was dry and the roads dully; the water infipid and inert. He attempted to ride on horfeback on the downs, but was not able to bear the fatigue for a diftance of more than a hundred yards. The neceffity of frequent bleedings kept down his ftrength, and his heaic paroxyfms continued, though lefs fevere. At this time, fufpeaing that his cough was irritated by the weft-winds bearing the va- pour from the fea, he refolved to try the effeas of an inland fituation, and fet off for Matlock in Derbyfliire. " During the journey he did not find the improve- ment he expeaed, but the nightly perfpirations began to diminifh ; and the extraordinary fatigue he expe- rienced proceeded evidently from his travelling in a poft-chaife, where he could not indulge in a recumbent pofition. The weather at Briftol had been hot, and the earth arid and dufty. At Matlock, during the month of June 1784, there was almoft a perpetual drizzle, the foil was wet, and the air moift and cold. Here, however, the patient's cough began to abate, and at intervals he found an opportunity of riding more or lefs on horfeback. From two or three hun- dred yards at a time, he got to ride a mile without ftopping ; and at length he was able to fit on horfe- back during a ride from Mafon's bath to the village of Matlock along the Derwent, and round on the op- pofitc Class II. i. 6-] OF SENSATION. 373 pofite banks, by the works of Mr. Arkwright, back to the houfc whence he Started, a diftance of five miles. On difmounting, however, he was feized with deliquium, and foon after the ftrength he had reco- covered was loft by an attack of the hemorrhoids of the moft painful kind, and requiring much lofs of blood from the parts affeaed. " On refleaion, it appeared that the only benefit received by the patient was during motion, and con- tinued motion could better be obtained in the courfe of a journey than during his refidence at any particular place. This, and other circumftances of a private but painful nature, determined him to fet out from Mat- lock on a journey to Scotland. The weather was now much improved, and during the journey he re- cruited his ftrength. Though as yet he could not fit upright at reft for half an hour together without a difpofition to giddinefs, dimnefs of fight, and deli- quium, he was able to fit upright under the motion of a poft-chaife during, a journey of from 40 to 70 miles daily, and his appetite began to improve, Still his cough continued, and his heaic flufliings, though the chills were much abated and very irregular. " The falutary effeas of motion being now more ftriking than ever, he purchafed a horfe admirably adapted to a valetudinarian in Dumfriesfhire, and be- ing now able to fit on horfeback for an hour together, he rode out feveral times a day. He fixed his refi- dence for a few weeks at Moffat, a village at the foot of the mountains whence the Tweed, the Clyde, and B b 3 the 374 DISEASES [Class II. i. 6. the Annan, defcend in different direaions; a fituation inland, dry, and healthy, and elevated about three hundred feet above the furface of the fea. Here his ftrength recovered daily, and he began to eat animal food, which for feveral months before he had not tatted. Perfevering in exercife on horfeback, he gra- dually increafed the length of his rides, according to his ftrength, from four to twenty miles a day ; and returning on horfeback to Lancafliire by the lakes of Cumberland, he arrived at Liverpool on the SlrSt of September, having rode the laft day of his journey 40 miles. " The two inferences of moft importance to be drawn from this narrative, are, firft, the extraordinary benefit derived from geftation in a carriage, and ftill more the mixture of geftation and exercife on horfeback, in arrefting or mitigating the heaic paroxyfm; and fe- condly, that in the florid confumption, as Dr. Beddoes terms it, an elevated and inland air is in certain cir- cumstances peculiarly falutary; while an atmofphere loaded with the fpray of the fea is irritating and nox- ious. The benefit derived in this cafe from exercife on horfeback, may lead us to doubt whether Syden- ham's praife of this remedy be as much exaggerated as it has of late been fuppofed. Since the publication of Dr. C, Smyth on the effeas of fwinging in lower- ing the pulfe in the heaic paroxyfm, the fubjea of this narrative has repeated his experiments in a great va- riety of cafes, and has confirmed them. He has alfo repeatedly feen the heaic paroxyfm prevented, or cut Short' Class II. 1.6.] OF SENSATION. 375 fhort, by external ablution of the naked body with tepid water. " So much was his power of digeftion impaired or vitiated by the immenfe evacuations, and the long continued debility he underwent, that after the cough was removed, and indeed for feveral years after the period mentioned, he never could eat animal food without heat and ffufhing, with frequent pulfe and extreme drowfinefs. If this drowfinefs was encou- raged, the fever ran high, and he awoke from dif- turbed fleep, wearied and depreffed. If it was refo- lutely refilled by gentle exercife, it went off in about an hour, as well as the increafed frequency of the pulfe. This agitation was however fuch as to inca- pacitate him during the afternoon for ftudy of any kind. The fame effeas did not follow a meal of milk and vegetables, but under this diet his ftrength did not recruit; whereas after the ufe of animal food it recovered rapidly, notwithftanding the inconvenience already mentioned. For this inconvenience he at laft found a remedy in the ufe of coffee immediately after dinner, recommended to him by his friend Dr. Perci- val. At firft this remedy operated like a charm, but by frequent ufe, and indeed by abufe, it no longer poffeffes its original efficacy. " Dr. Falconer, in his Differtation on the Influence of the Paffions and ASfeaions of the Mind on Health and Difeafe, fuppofes that the cheerfulnefs which attends heaic fever, the ever-Springing hope, which brightens the gloom of the consumptive patient, increafes the B b 4 difeafed 3;6 DISEASES [Class If. i. 6. difeafed aaion?, and haftens his doom. And hence he is led to enquire, whether the influence of fear might not be fubltituted in fuch cafes to that of hope with advantage to the patient ? This queftion 1 Shall not prefume to anfwer, but it leads me to fay Some- thing of the ftate of the mind in the cafe juft re- lated. * # " The patient, being a phyfician, was not ignorant of his danger, which fome melancholy circumftances ferved to imprefs on his mind. It has already been mentioned, that his mother and grandfather died of this difeafe. It may be added, that in the year pre- ceding that on which he himfelf was attacked, a filter of his was carried off by confumption in her 17th year ; that in the fame winter in which he fell ill, two other fitters were feized with the fame fatal difor- der, to which one of them fell a viaim during his refidence at Briftol, and that the hope of bidding a laft adieu to the other was the immediate caufe of his journey to Scotland, a hope which, alas ! was indulged in vain. The day on which he reached the end of his journey, her remains were committed to the duft! It may be conjeaured from thefe circumftance3, that whatever benefit may be derived from the apprehenfion of death, muft in this cafe have been obtained. The expectation of this iffue was indeed for fome time fo fixed that it ceafed to produce much agitation; in conformity to that general law of our nature, by v Ire h almoft all men fubmit with compofure to a fate • hat h forefeen. and that appears inevitable. As how- ever Class II. i. 6.} OF SENSATION. 377 ever the progrefs of difeafe and debility feemed to be arretted, the hope and the love of life revived, and produced, from time to time, the obfervations and the exertions already mentioned. " Wine and beer were rigoroufly abftained from during fix months of the above hiftory ; and all the blood which was taken was even *to the laft b'uffy." Feb. 3, 1795. 8. Febris fcrophulofa. The heaic fever occafioned by ulcers of the lymphatic glands, when expofed to the air, does not differ from that attending pulmonary confumption, being accompanied with night-fweats and occafional diarrhcea. M. M. The bark. Opium internally. Externally ceruffa and bark in fine powder. Bandage. Sea- bathing. See Clafs I. 2. 3. 21. and II. 1.4. 12. 9. Febris ifchiadica. A heaic fever from an open ulcer between the mufcles of the pelvis, which differs not from the preceding. If the matter in this fituation lodges till part of it, I fuppofe, becomes putrid, and aerates the other part : or till it becomes abforbed from fome other circumftance ; a fimilar heaic fever is produced, with night-fweats, or diarrhoea. Mrs.-----, after a lying in, had pain on one fide of her loins, which extended to the internal part of the thigh on the Slime fide. No fluauation of matter could be felt; flie became heaic with copious night- fweats, and occafional diarrhoea, for four or five weeks { 37* DISEASES [Class II. i. 6. weeks; and recovered by, I fuppofe, the total ab- forption of the matter, and the reunion of the walls of the abfcefs. See Clafs II. i. 2. 18. ro. Febris Arthrcpuodica. Fever from the matter of difeafed joints. Does the matter from fuppurating bones, which generally has a very putrid fmell, pro- duce heaic fever, or typhus ? See Clafs II. 1.4. 16. 11. Febris a pure confagiofo. Fever from contagious pus. When the contagious matters have been pro- duced on the external fiabit, and in procefs of time become abforbed, a fever is produced in confequence of this reabforption; which differs with the previous irritability or inirritability, as well as with the fenfibi- lity of the patient. 12. Febris variolofa fecundaria: Secondary fever of fmall-pox. In the diftina fmall-pox the fever is of the fenfitive irritated or inflammatory kind ; in the confluent fmall-pox it is of the fenfitive inirritated kind, or typhus gravior. In both of them the fwelling of the face, when the matter there begins to be ab- forbed, and of the hands, when the matter there begins to be abforbed, fhew, that it ftimulates the capillary veffels or glands, occafioning an increafed fecretion greater than the abforbents can take up, like the aaion of the cantharides in a blifter ; now as the ap- plication of a blifter on the Skin frequently occafions rhe ftrangury, which fhews, that fome part of the cantharides Class II. i. 6.] OF SENSATION. 379 cantharides is abforbed ; there is reafon to conclude, that a part of the matter of fmall-pox is abforbed, and thus produces the fecondary fever. See Clafs II. 1. 3. 9. And not fimply by its ftimulus on the furface of the ulcers beneath the fcabs. The exfudation of a yellow fluid from beneath the confluent eruptions on the face before the height is fpoken of in Clafs II. 1. 3. 2. The material thus abforbed in the fecondary fever of fmall-pox differs from that of open ulcers, as it is only aerated through the elevated cuticle; and fe- condly, becaufe there is not a conftant fupply of frefh matter, when that already in the puftules is exhaufted, either by abforption, or by evaporation, or by its induration into a feab. Might not the covering the face afliduouily and exaaiy with plafters, as with ce- rate of calamy, or with minium plafter, by precluding the air from the puftules, prevent their contraaing a contagious, or acefcent, or fever-producing power? and the fecondary fever be thus prevented entirely. If the matter in thofe puftules on the face in the con- fluent fmall-pox were thus prevented from oxygenation, it is highly probable, both from this theory, and from the faas before mentioned, that the matter would not erode the fkin beneath them, and by thefe means no marks or fears would fucceed. 13. Febris carcinomatofa. Fever from the matter of cancer. In a late publication the pain is faid to be relieved, and the fever cured, and the cancer eradi- cated, 3F^ DISEASES [Class II. i. 6. cated, by the application of carbonic acid gas, or fixed air. See Clafs II. i. 4. 16. 14. Febris venerea. From, the abforption of the matter from venereal ulcers and fuppurating bones, See Syphilis, II. 1.5. 2. M. M. Any mercurial calx. Sarfaparilla ? Me- zereon ? 15. Febris a fanie putrida. Fever from putrid fanies. When parts of the body are deftroyed by external violence, as a bruife, or by mortification, a putrefaaion foon fucceeds ; as they are kept in that degree of warmth and moifture by their adhefion to the living parts of the body, which moft forwaids that procefs. Thus the Sloughs of mortified parts of the tonfils give fetor to the breath in fome fevers ; the matter from putrefying teeth, or other fuppurating bones, is particularly offensive ; and even the fcurf, which adheres to the tongue, frequently acquires a bitter tafte from its incipient putridity. This material differs from thofe before mentioned, as its deleterious property depends on a chemical rather than an animal proeeh. 16. Febris puerpera. Puerperal fever. It appears from fome late diffeftions, which have been published, of thofe women who have died of the puerperal fever, that matter has been formed in the omentum, and fcund in the cavity of the ahdomen, with fome blood Class II. i. 6.] OF SENSATION. 3?j blood or fanies. Thefe parts are fuppofed to have been injured by the exertions accompanying labour; and as matter in this vifcus may have been produced without much pain, this difeafe is not attendee with arterial ftrength and hard full pulfe like the infl . ama- tion of the uterus ; and as the fever is of the inh rita- tivecr typhus kind, there is reafon to believe, that'he previous exhauftion of the patient during labour may contribute to its produaion ; as well as the abiorp ion of a material not purulent but putrid ; which is formed by the delay of extravafated or dead matter produced by the bruifes of the omentum, or other vifcera, in the efforts of parturition, rather than by purulent matter, the confequence of fuppuration. The pulfe is generally about 120 when in bed and in the morn- ing ; and is increafed to 134, or more, when the patient Sits up, or in the evening paroxyfm. The pulfe of all very weak patients increafes in frequency when they fit up ; becaufe the expenditure of fenforial power neceffary to preferve an erea pofture deduas fo much from their general Strength ; and hence the pulfe becomes weaker, and in confequence quicker. See Sea. XII. 1.4. In this fever time muft be allowed for the abforption of the matter. Very large and repeated quantities of the bark, by preventing fufficient food from being taken, as bread, and wine, and water, I have thought has much injured the patient; for the bark is not here given as in intermittent fevers to prevent the paroxyfin, but fimply to ftrengthen the patient by increafing the power 3&2 DISEASES [Class II. I. 6. power of digeftion. About two ounces of decoaion of bark, with four drops of laudanum, and a dram of fweet fpirit of vitriol, once in fix hours, and a glafs of wine between thofe times, with panada, or other food, I have thought of moft advantage, with a fmall blifter occafionally. Where not only the ftomach but alfo the bowels arc much diftended with air, fo as to found on ftriking them with the fingers, the cafe is always dangerous, generally hopelefs; which is more fo in proportion to the quicknefs of the pulfe. Where the bowels are diftended two drops of oil of cinnamon fliould be given in the panada three or four times a day. 17. Febris a fphacelo. Fever from mortification. This fever from abforption of putrid matter is of the inirritative or typhus kind. See the preceding article. M. M. Opium and the bark are frequently given in too great quantity, fo as tojnduce confequent debility, and to opprefs the power of digeftion. ORDO Class II. i. 7/J - OF SENSATION. 3*3 ORDO I. Increafed Senfation. GENUS VII. With increafed Aclion cf the Organs of Senfe. SPECIES. I. Delirium febrile. Paraphrofyne. Tlie ideas in delirium confift of thofe excited by the fenfation of pleafure or pain, which precedes them, and the trains of other ideas affociated with thefe, and not of thofe excited by external irritations or by voluntary exer- tion. Hence the patients do not know the room which they inhabit, or the people who furround them ; nor have they any voluntary exertion, where the delirium is complete ; fo that their efforts in walking about a room or rifing from their bed are unfteady, and pro- duced by their catenations with the immediate affec- tions of pleafure or pain. See Seaion XXXIII. 1. 4. By the above circumstances it is diftinguiflied from madnefs, in which the patients well know the per- fons of their acquaintance, and the place where they are; and perform all the voluntary actions with ftea- dinefs and determination. See Sea. XXXIV. 2. 2. Delirium is fometimes lefs complete, and then a new face and louder voice ftimulate the patient to attend to them for a few moments; and then they relapfe again into perfea delirium. At other times a delirium affeas but one fenfe, and the perfon thinks he 384 DISEASES [Class II. i. 7. he fees things which do not exift; and is at the fame time fenfible to the questions which are aSked him, and to the tafte of the food which is offered to him. This partial delirium is termed an hallucination of the difordered organ; and may probably arife from the origin of one nerve of fenfe being more liable to inflammation than the others ; that is, an exuberance of the fenforial power of fenfation may effea it; which is therefore thrown into aaion by Slighter fenfitive catenations, without being obedient to external ftimu- lus, or to the power of volition. The perpetual flow of ideas in delirium is owing to the fame circumftance, as of thofe in our dreams ; namely, to the defea or paralyfis of the voluntary power; as in hemiplagia, when one fide of the body is paralytic, and thus expends lefs of the fenforial power, the limbs on the other fide are in conftant mo- tion from the exuberance of it. Whence lefs fenforial power is exhaufted in delirium, than at other times, as well as in fleep ; and hence in fevers with great debility, it is perhaps, as well as the ftupor, rather a favourable circumftance; and when removed by nu- merous blifters, the death of the patient often follows the recovery of his understanding. See Clafs I. 2. 5.6. and I. 2. 5. ic. Delirium in difeafes from inirritability is fometimes preceded by a propenfity to furprife. See Clafs I. 1. 5. 12. M. M. Fomentations of the Shaved head for an hour repeatedly. A blifter on the head. Riling from 1 bed. Class II. i. 7.] OF SENSATION-. 385 bed. Wine and opium, and fometimes venefeaion in fmall quantity by cupping, if the ftrength of the arte- rial fyftem will allow it. 2. Delirium mdniacale. Maniacal delirium. There is another kind of delirium, defcribed in Sea. XXXIII. 1. 4. which has the increafe of pleafurable or painful fenfation for its caufe, without any diminution of the other fenforial powers; but as this excites the patient to the exertion of voluntary aaions, for the purpofe of obtaining the objea of his pleafurable ideas, or avoiding the objea of his painful ones, fuch as perpe- tual prayer, when it is of the religious kind, it be- longs to the infanities defcribed in Clafs III. 1. 2. 1. and is more properly termed hallucinatio maniacalis. 3. Delirium ebrietatis. The drunken delirium is in nothing different from the delirium attending fevers except in its caufe, as from alcohol, or other poifons. When it is attended with an apopleaic ftupor, the pulfe is generally low ; and venefeaion I believe fome- times deftroys thofe, who would otherwife have reco- vered in a few hours. M. M. Diluting liquids. An emetic. 4. Somnium. Dreams constitute the moft complete kind of delirium. As in thefe no external irritations are attended to, and ihe power of volition is entirely fufpended ; So that the fenfations of pleafure and pain, v. :th their affociations, alone excite the endlefs trains Cc of 3.56 DISEASES [Class II. i. 7. of our fleeping ideas ; as explained in Sea. XVIII. on Sleep. 5. Hallucinatio vifu's. Deception of fight. Thefe vifual hallucinations are perpetual in our dreams ; and fometimes precede general delirium in fevers ; and fometimes belong to reverie, and to infanity. See Clafs III. 1. 2. 1. and 2. and muft be treated accord- ingly. Other kinds of vifual hallucinations occur by moon- light ; when objeas are not feen So diftinaiy as to produce the ulual ideas affociated with them, but ap- pear to us exaaiy as they are feen. Thus the trunk of a tree appears a flat Surface, inftead of a cylinder as by day, and \* e are deceived and alarmed by feeing things as they really are feen. See Berkley on Vifion. 6. Hallucinatio auditus. Auricular deception fre- quently occurs in dreams, and fometimes precedes ge- neral delirium in fevers; and fometimes belongs to vertigo, and to reverie, and to infanity. See Sea. XX. 7. and Clafs III. 1. 2. 1. and 2. 7. Rubor a colore. The bluSh from heat is occa- fioned by the increafed aaion of the cutaneous veffels in confequence of the increafed fenfation of heat. See Clafs I. 1. 2. 1. and 3. 8. Rubor jucunditatis. The bluSh of joy is owing to the increafed aaion of the capillary arteries, along with Class II. i. 7-] OF SENSATION. 367 with that of every moving veffel in the body, from the increafe of pleafurable fenfation. 9. Priapifmus amatorius. Amatorial priapifm. The blood is poured into the cells of the corpora cavernofa much fafter than it can be reabforbed by the vena penis, owing in this cafe to the pleafurable fenfation of love increafing the arterial aaion. See Clafs I. 1. 4. 6. 10. Difientio mamularum. The teats of female animals, when they give lick, become rigid and erea- cd, in the fame manner as in the laft article, from the pleafurable fenfation of the love of the mother to her offspring. Whence the teat may properly be called an organ of fenfe. The nipples of men do the fame when rubbed with the hand. See Clafs I. 1, 4. 7, C c 2 ORDO J88 > DISEASES [Class II. z. u ORDO II. .^ Decreafed Senfation. GENUS I. Of the General Syfiem. SPECIES. i. Stultitia infenfibilis. Folly from infenfibility. The pleafure or pain generated in the fyftem is not fufficient to promote the ufual aaivity either of the fenfual or mufcular fibres. 2. Tccdium vita. Ennui. Irkfomenefs of life. The pain of lazinefs has been thought by fome philo- fophers to be that principle of aaion, which has ex- cited all our induftry, and distinguished mankind from the brutes of the field. It is certain that, where the ennui exifts, it is relieved by the exertions of our minds or bodies, as all other painful fenfations arc re- lieved ; but it depends much upon our early habits, whether we become patient of lazinefs, or inclined to aaivity, during the remainder of our lives, as other animals do not appear to be affeaed with this malady ; which is perhaps lefs owing to deficiency of pleafurable fenfation, than to the fuperabundancy of voluntary power, which occafions pain in the mufcles by its ac- cumulation ; as appears from the perpetual motions of a fquirrel confined in a cage. 3. Partfis fenfitiva. Weaknefs of the whole fyftem from infenfibility, ORDO Class II. 2. r.] OF SENSATION. 3S9 ORDO II. Decreafed Senfation. GENUS II. Of Particular Organs. SPECIES. 1. Anorexia. Want of appetite. Some elderly people, and thofe debilitated by fermented liquors, are liable to lofe their appetite for animal food ; which is probably in part owing to the deficiency of gaftric acid, as well as to the general decay of the fyftem : elderly people will go on years without animal food; but inebriates foon fink, when their digeftion becomes fo far impaired. Want of appetite is fometimes pro- duced by the putrid matter from many decaying teeth being perpetually mixed with the faliva, and thence affeaing the organ of tafte, and greatly injuring the digeftion. M. M. Fine charcoal powder diffufed in warm wa- ter held in the mouth frequently in a day, as in Clafs I. 1. 4. 4. or folution of alum in water. Extraa the decayed teeth. An emetic. A blifter. Chaiybeates. Vitriolic acid. Bile of an ox infpiffated, and made into pills; 20 grains to be taken before dinner and fupper. Opium half a grain twice a day. All the ftrength we poffefs is ultimately derived from the food, which we are able to digeft ; whence a total debility of the fyftem frequently follows the C c 3 want 39© DISEASES [Class II. 2. 2, want of appetite, and of the power of digeftion. Some young ladies I have obferved to fall into this general debility, fo as but juft to be able to -walk about; which 1 have fometimes aferibed to their volun- tary fafting, when they believed themfelves too plump ; and who have thus loft both their health and beaiuy by too great abstinence, which could never be reftored. I have feen other cafes of what may be termed anorexia epileptica, in which a total lofs of appetite, and of the power of digeftion, fuddenly occurred along with epileptic fits. Mifs B. a girl about eighteen, apparently very healthy, and rather plump, was feized with fits, which were at firft called hyfte- rical; they occurred at the end of menftruation, and returned very frequently with total lofs of appetite. She was relieved by venefeaion, blifters, and opiates ; her ftrength diminifhed, and after fome returns of the fits, She took to her bed, and has furvived 15 or 20 years ; She has in general eaten half a potatoe a day, and feldom fpeaks, but retains her fenfes, and had many years occafional returns of convulfion. I have feen two fimilar cafes, where the anorexia, or want of appetite, was in lefs degree ; and but juft fo much food could be digefted, as fupplied them with fufficient Strength to keep from the bed or Sofa for half the day. As well as I can recollea, all thefe patients were attended with weak pulfe, and cold pale Skin ; and received benefit by opium, from a quarter of a grain to a grain four times a day. See Clafs III. 1. 1. 7. and III. 1. 2. 1. and III. 1. 2. 20. 2* Adipfio, Class II. 2. 2.] OF SENSATION. 3,91 2. Adipfia. Want of thirft. Several of the inferior people, as farmers wives, have a habit of not drink- ing with their dinner at all, or only take a fpoon- ful or two of ale after it. I have frequently ob- ferved thefe to labour under bad digeftion, and de- bility in confequence ; which I have aferibed to the too great ftimulus of folid food undiluted, destroy- ing in procefs of time the irritability of the Sto- mach. 3. Impotentia (agenefia"). Impotency much feldomer happens to the male fex than fterility to the female fex. Sometimes a temporary impotence occurs from baShfulnefs, or the interference of fome voluntary exertion in the produaion of an effea, which Should be performed alone by pleafurable fenfation. One, who was foon to be married to a lady of fuperior condition to his own, expreffed fear of not fucceeding on the wedding night; he was advifed fo take a grain of opium before he went to bed, and to accuftom himfelf to fleep with a woman previoufly, but not to enjoy her, to take off his baflifulnefs; which fucceeded to his wifli. M. M. Chaiybeates. Opium. Bark. Tinaure of cantharides. 4. Sfcrilitas. Barrcnnefs. One of the ancient me- dical writers afferts that the female fex become preg- nant with moft certainty at or near the time of, menstruation. This is not improhable, fince thefe C c 4 monthly 39* DISEASES [Class II. 2. 2. monthly periods feem to refemble the monthly vene- real orgafm of fome female quadrupeds, which be- come pregnant at thofe times only ; and hence the computation of pregnancy is not often erroneous, though taken from the laft menftruation. See Seaion XXXVI. 2. 3. M. M. Opium a grain every night. Chaiybeates in very fmall dofes. Bark. Sea-bathing. 5. Infenfibilitas artuum. As in fome paralytic limbs. A great infenfibility fometimes accompanies the torpor of the fkin in cold fits of agues. Some parts have retained the fenfe of heat, but not the fenfe of touch. See Sea. XVI. 6. M. M. Friaion with flannel. A blifter. Warmth. 6. Dyfuria infenfitiva* Infenfibilty of the bladder. A difficulty or total inability to make water attends fome fevers with great debility, owing to the infenfi- bility or inirritability of the bladder. This is a dan- gerous but not always a fatal fymptom, M. M. Draw off the water with a catheter. Affift the patient in the exclufion of it by comprefling the lower parts of the abdomen with the hands. Wine two ounces. Peruvian bark one dram in decoaion, every three hours alternately. Balfam of copaiva. Oil of almonds, with as much camphor as can be diffolved in it, applied as a liniment rubbed on the region of the bladder and perinneum, and repeat- ed every four hours, was ufed in this difeafe with 1 fuccefQ Class II. 2. 2.J OF SENSATION. 393 fuccefs by Mr. Latham. Med. Comment. 1791, p. 213. 7. Accumulatio alvina. An accumulation of feces in the reaum, occafioned by the torpor, or infenfi- bility, of that bowel. But as liquids pafs by thefe accumulations, it differs from the conftipatio alvi, which is owing to too great abforption of the alimen- tary canal. Old milk, and efpecially when boiled, is liable to induce this kind of coftivenefs in fome grown perfons ; which is probably owing to'their not poffeffing fufficient gaftric acid to curdle and digeft it; for as both thefe proceffes require gaftric acid, it follows, that a greater quantity of it is neceffary, than in the digeftion of other aliments, which do not previously require being curdled. This ill digefted milk not Sufficiently ftimu- lating the reaum, remains till it becomes a too folid mafs. On this account milk feldom agrees with thofe, who are fubjea to piles, by inducing coftivenefs and large ftools. i.'.'l, M. Extraa the hardened fcybala by means of a marrow-fpoon ; or by a piece of wire, or of whale- bone bent into a bow, and introduced. Injeaions of oil. Caftor oil, or oil of almonds, taken by the mouth. A large clyfter of fmoke of tobacco. Six grains of rhubarb taken every night for many months. Aloes. An endeavour to eftabliSh a habit of evacuation at a certain hour daily. See Clafs I. 1.3. 5. ORDO 394 DISEASES [<£lass II. 3. 1. ORDO III. Retrograde Senfitive Motions. GENUS I. Of Excretory Duels. The retrograde aaion of the cefophagus in rumi- nating animals, when they bring up the food from their firft ftomach for the purpofa of a fecond mafti- cation of it, may probably be caufed by agreeable fenfation: fimilar to that which induces them to fwallow it both before and after this fecond *rloca- tion ; and then this retrograde aaion properly^belongs to this place, and is erroneously put at the head of '.he order of irritative retrograde motions. Clafs I. c;. 1. 1. SPECIES. 1. Ureterum motus retrogreffus. When a ftone has advanced into the ureter from the pelvis of the kidney, it is fometimes liable to be returned by the retrograde motion of that canal, and the patient obtains fallacious eafe, till the ftone is again puflied into the ureter. 2. Urethra; motus retrogreffus. There have been inftances of bougies being carried up the urethra into the bladder moft probably by an inverted motion of this canal; for which fome have undergone an operation fimilar to that for the extraaion of a ftone. A cafe is related in fome medical publication, in which Class II. 3- 1.] OF SENSATION. 395 which a catgut bougie was carried into the bladder, and after remaining many weeks, was voided piece- meal in a femi-diffolved ftate. Another cafe is related of a French officer, who ufed a leaden bougie ; which at length found its way into the bladder, and was, by injeaing crude mercury, amalgamated and voided. In the fame manner the infeaion from a fimple gonorrhoea is probably carried further along the courfe of the urethra ; and fmall ftones frequently defcend fome way into the urethra, and are again carried up into the bladder by the inverted aaion of this canal. 3. Duel us choledochi motus retrogreffus. The concre- tions of bile, called gall-ftones, frequently enter the bile-dua, and give violent pain for fome hours; and return again into the gall-bladder, by the retrograde aaion of this dua. May not oil be carried up this dua, when a gall-ftone gives great pain, by its retro- grade fpafmodic aaion ? See Clafs I. 1. 3. 8. M. M. Opium a grain and half. ■S'liL 39<5 DISEASES [Class III. 1HE ORDERS AND GENERA OF THE THIRD CLASS OF DISEASES. CLASS III. DISEASES OF VOLITION. ORDO I. Increafed Volition* GENERA. i. With increafed aaions of the mufcles. i. With increafed aaions of the organs of fenfe. ORDO II. Decreafed Volition. GENERA. i. With decreafed aaions of the mufcles. 2. With decreafed aaions of the organs of fenfe. THE Class III. i. i.] OF VOLITION. 397 THE ORDERS, GENERA, AND SPECIES, OF THE THIRD CLASS OF DISEASES. CLASS III. DISEASES OF VOLITION. ORDO I. Increafed Volition. GENUS I. With Increafed Aclions of the Mufcles* SPECIES. i. faclitatio. 2. Tremor febrilis. 3. Clamor. 4. Rifus. 5. Convulfio. -------- debilis. 6.-------dolorifica. 7. Epilepfia. 8. ———- dolorifica. 9. Somnambulifmus. 10. Afihma convulfivum. 14.-----dolorificum. 12. Stridor dentium. 13. Tetanus trifmus. 14.------dolorificus. 15. Hydrophobia. Reftleffnefs. Febrile trembling. Screaming. Laughter. Convulfion. --------weak. --------painful. Epilepfy. ------painful. Sleep-walking. Afthma convulfive. —:----painful. Gnafhing of the teeth. Cramp of the jaw. ,« • — painful. Dread of water. GENUS DISEASES [Class III. 1.2. GENUS II. With increafed Aclions of the Organs of Senfe* SPECIES. 1. 2. 3- 4- 5- 6. 7- 8. 9- 10. 11. 12. i3- 14. 15- 16. 18. 19- 20. 21. 22. 23- 24- Mania mutabilis* Studium inane. Vigilia. Erotomania. Amorfui. Nofialgia. Spes religiofa. Superbiaftemmatis. Ambitio. Maror. Tcedium vita. Mutable madnefs. Reverie. Watchfulnefs. Sentimental love. Vanity. Defire of home. Superftitious hope. Pride of family. Ambition. Grief. Irkfomencfs of life. Defiderium pulchriiudi- Lofs of beauty. Paupcrlatis timor. Let hi timor. Orci timor. Satyr iafis, Ira. Rabies. Citta. Cacofitia. Syphilis imaginaria. , Pfora imaginaria. Tabes imaginaria. Sympathia alicna. , EducMio heroica* Fear of poverty. -----of death. -----of hell. Luft. Anger. Rage. Depraved appetite. Averfion to food. Imaginary pox. .---------itch. ---------tabes. Pity. Heroic education. ORDO Class III. 2. 1.] OF VOLITION. 39? ORDO II. Decreafed Volition. GENUS I. With decreafed Aclions of the Mufcles. SPECIES. 1. Laffitudo. 2. Vacillatio fcnilis. 3. Tremor fenilis. a. Brachiorum paralyfis. 5. Raucedo paralytica. 6. Vefica urinaria paraly- fis. 7. Recli paralyfis. 8. Parefis voluntaria. 9. Catalepfis. 10. Hemiplegia. 11. Paraplegia. 12. Somnus. 13. Incubut. 1 a. Lethargus. 15. Syncope epileptica. 16. Apoplexia. 17. -Mors a frigore. Fatigue. See-faw of old age. Tremor of old age. Palfy of the arms. Paralytic hoarfenefs. Palfy of the bladder. Palfy of the reaum. Voluntary debility. Catalepfy. Palfy of one fide. Palfy of the lower limbs. Sleep. Night-mare. Lethargy. Epileptic fainting. Apoplexy. Death from cold. GENUS DISEASES [Class III. 2. 2. GENUS II. With decreafed Aclions of the Organs of Senfe. SPECIES. 1. Recolleclionis jaclura. Lofs of recolfeaion. 2. Siultitia voluntaria.^ Voluntary folly. 3. Crcdulitas. Credulity. Class III. I. 1.] OF VOLITION. 4-* CLASS III. J&ISEASES OF VOLITION. ORDO I. Increafed Volition. GENUS I. Increafed Aclions of the Mufcles. We now Step forward to confider the difeafes of volition, that fuperior faculty of the fenforium, which gives us the power of reafon, and by its facility of aaion diftinguiflies mankind from brute animals ; which has effeaed all that is great in the world, and fuper- impofed the works of art on the Situations of nature. Pain is introduced into the fyftem either by excefs or defea of the aaion of the part. (Sea. IV. 5.) Both which circumftances feem to originate from the accumulation of fenforial power in the affeaed organ. Thus when the Skin is expofed to great cold, the aaivity of the cutaneous veffels is diminiflied, and in confequence an accumulation of fenforial power obtains in them, becaufe they are ufually excited into inceffant motion by the ftimulus of heat, as explained in Sea. XII. 5. 2. Contrary wife, when the veffels of the Skin are expofed to great heat, an excefs of fenforial power is alfo produced in them, which is derived thither by the increafe of ftimulus above what is natural. This accounts for the relief which is received in all kinds of pain by any violent extertions of our mufcles D d or 40* DISEASES [Class III. i. t, or organs of fenfe; which may thus be in part af- eribed to the exhauftion of the fenforial power by fuch exertions. But this relief is in many cafes fo instan- taneous, that it feems neverthelefs probable, that it is alfo in part owing to the different manner of progref- fion of the two fenforial powers of fenfation and voli- tion ; one of them commencing at fome extremity of the fenforium, and being propagated towards the cen- tral parts of it; and the other commencing in the central parts of the fenforium, and being propagated towards the extremities of it; as mentioned in Sea. XI. 2. I. Thefe violent voluntary exertions of our mufcles or ideas to relieve the fenfatfon of pain constitute convul- fions and madnefs; and are distinguished from the mufcular aaions owing to increafed fenfation, as in fneezing, or coughing, or parturition, or ejeaio fe- minis, becaufe they do not contribute to diflodge the caufe, but only to prevent the fenfation of k* In two cafes of parturition, both of young women with their firft child, I have feen general convulfions occur from excefs of voluntary exertion, as above defcribed, in- stead of the aaions of particular mufcles, which ought to have been excited by fenfation for the exclufion of the fetus. They both became infenfible, and died after fome hours; from one of them the fetus was cxtraacd in vain. I have heard alfo of general con- vulfions being excited inftead of the aaions of the muf- culi acceleratores in the ejeaio feminis, which termi- *ated fatally. See Clafs III. i. i. 7. Thefe Class III. i. i.] OF VOLITION. 40$ Thefe violent exertions are moft frequently excited in confequence of thofe pains, which originate from defea of the aaion of the part. See Sea. XXXIV. 1. and 3. The pains from excefs and defea of the aaion of the part are diftinguifliable from each other by the former being attended with increafe of heat in the pained part, or of the whole body ; while the latter not only exift without increafe of heat in the pained part, but are generally attended with coldnefs of the extremities of the body. As foon as thefe violent aaions of our mufcular or fenfual fibres for the purpofe of relieving pain ceafe to be exerted, the pain recurs; whence the reciprocal eontraaion and relaxation of the mufcles in convulfion, and the intervals of madnefs. Otherwife thefe violent exertions continue, till fo great a part of the fenforial power is exhaufted, that no more of it is excitable by the faculty of volition; and a temporary apoplexy fucceeds, with fnoring as in profound fleep; which fo generally terminates epileptic fits. When thefe voluntary exertions become fo connea- ed with certain difagreeable fenfations, or with irri- tations, that the effort of the will cannot reftrain them, they can no longer in common language be termed voluntary ; but neverthelefs belong to this clafs, as they are produced by excefs of volition, and may ftill not improperly be called depraved voluntary aaions. See Sea. XXXIV. 1. where many motions in common language termed involuntary are Shewn to depend on excefs of volition. D d 2 When 4*4 DISEASES [Class III. i. u When thefe exertions from excefs of volition, which in common language are termed involuntary motions, cither of mind or body, are perpetually exerted in weak constitutions, the pulfe becomes quick ; which is occafioned by the too great expenditure of the fen- forial power in thefe unceafing modes of aaivity. In the fame manner as in very weak people in fevers, the pulfe fometimes increafes in frequency to 140 Stroke* m a minute, when the patients ftand up or endeavour to walk; and fubfides to no, when they lie down again in their beds. Whence it appears, that when a very quick pulfe accompanies convulfion or infanity, it fimply indicates the weaknefs of the patient; that is, that the expenditure of fenforial power is too great for the fupply of it. But if the ftrength of the pa- tient is not previoufly exhaufted, the exertions of the mufcles are attended with temporary increafe of circu- lation, the reciprocal fwellings and elongations of their bellies puSh forwards tliG arterial blood, and promote the abforptidn of the venous blood ; whence a tempo- rary increafe of fecretion and of heat, and a ftronger pulfe. SPECIES. 1. Jaclitatio. Reftleffnefs. There is one kind of rcftleffnefs attending fevers, which confifts in a fre- quent change of pofture to relieve the uneafinefs of the preffure of one part of the body upon another, when the fenfibility of tJ fyftem, or of fome parts of it, is increafed by mflammauon, as in the lumbago '% which may Class III J. i.] OF VOLITION. 4,05 may fometimes be diftinguifhed in its early ftage by the inceffant defire of the patient to turn himfelf in bed. But there is another reftleffncfs, which approaches towards writhing or contortions of the body, which is a voluntary effort to relieve pain ; and may be efteemed a flighter kind of convulfion, not totally unreSfrainable by oppofite orcounter-aaing volitions. M. M. A blifter. Opium. Warm bath. 2. Tremor febrilis. Reciprocal convulfions of the fubcutaneous mufcles, originating from the pain of the fenfe of heat, owing to defea of its ufual ftimulus, and confequent accumulation of fenforial power in it. The aaual deficiency of heat may exift in one part of the body, and the pain' of cold be felt moft vividly in fome other part, anociated with it by fenfitive fym- pathy. So a chillnefs down the back is firft attended to in ague-fits, though the difeafe perhaps commences with the torpor and confequent coldnefs of fome inter- nal vifcus. But in whatever part of the fyftem the defea of heat exifts, or the fenfation of it, the con- vulfions of the fubcutaneous mufcles exerted to relieve it are very general; and, if the pain is ftill greater, a chattering of fhe teeth is added, the" more fuddenly to cxhauft the fenforial power, and becaufe the teeth are very fenfible to cold. Thefe convulfive motions are neverthelefs reftraln- able by violent voluntary counteraaion ; and as their intervals are owing to the pain of cold being for a time relieved by their exertions, they may be compared D d 3 t« 4«6 DISEASES [Class III. i. i. to laughter, except that there is no interval of pleafure preceding each moment of pain in this as in the latter. M. M. See I. 2. 2. 1. 3. Clamor. Screaming from pain. The talkative animals, as dogs, and fwine, and children, fcream moft, when they are in pain, and even from fear ; as they have ufed this kind of exertion from their birth moft frequently and moft forcibly ; and can therefore fooner cxhauft the accumulation of fenforial power in the affeaed mufcular or fenfual organs by this mode of exertions ; as defcribed in Sea. XXXIV. 1. 3, This facility of relieving pain by fcreaming is the fource of laughter, as explained below. 4. Rifus. The pleafurable fenfations, which occa- fion laughter, are perpetually paffing into the bounds of pain ; for pleafure and pain are often produced by different degrees of the fame ftimulus; as warmth, light, aromatic or volatile odours, become painful by their excefs ; and the tickling on the foles of the feet in children is a painful fenfation at the very time it produces laughter. When the pleafurable ideas, which excite us to laugh, pafs into pain, we ufe feme exertion, as a fcream, to relieve the pain, but foon Stop it again, as we are unwilling to lofe the pleafure ; and thus we repeatedly begin to fcream, and Stop again, alternately. So that in laughing there are three ftages, firft of pleafure, then pain, then an exertion to relieve that pain. See Sea. XXXIV. 1. 3. Every Class III. i. i.] OF VOLITION. 4^> Every one has been in a fituation, where fome ludicrous circumftances has excited him to laugh ; and at the fame time a fenfe of decorum has forbid the ex- ertion of thefe interrupted fcreams ; and then the pain has become fo violent, as to occafion him to ufe fome other great aaion, as biting his tongue, and pinching himfelf, in lieu of the reiterated fcreams which consti- tute laughter. 5. CoHvulfio. Convulfion. When the pains from defea or excefs of motion are more diftreffing than thofe already defcribed, and are not relievable by fuch partial exertions, as in fcreaming, or laughter, more general convulfions occur; which vary perhaps acr cording to the fituation of the pained part, or to fome previous affociations formed by the early habits of life. When thefe convulfive motions bend the body forwards, they are termed emprofthotonoi; when they bend it backward, they are termed opifthotonoi, They frequently fucceed each other, but the opiftho- tonoi are generally more violent; as the mufcles, which erea the body, and keep it erea,' are naturally in more conftant and more forcible aaion than their antagonists. The caufes of convulfion are very numerous, as from toothing in children, from worms or acidity in their bowels, from eruption of the diftina fmall-pox, and laftly, from breathing too long the air of an un- ventilated bed-room. Sir G. Baker, in the Tranf- aftions of the College, defcribed this difeafe, and de- D d 4 tcfted 408 DISEASES [Class III. i. : teaed its caufe ; where many children in an orphan- houfe were crowded together in one chamber without a chimney, and were almoft all of them affeaed with convulfion; in the hofpital at Dublin, many died of convulfions before the real caufe was underftood. See Dr. Beddoes's Guide to Self-prefervation. In a large family, which I attended, where many female fervants flept in one room, which they had contrived to render inacceffible to every blaft of air; I faw four who were thus feized with convulfions, and who were believed to have been affeaed by fympathy from the firft who fell ill. They were removed into more airy apartments, but were fome weeks before they all re- gained their perfea health. Convulfion is diftinguifhed from epilepfy, as the pa- tient does not intirely lofe all perception during the paroxyfm. Which only Shews, that a lefs exhauftion of fenforial power renders tolerable the pains which caufe convulfion, than thofe which caufe epilepfy. The hyfteric convulfions are distinguished from thofe, owing to other caufes, by the pretence of the expec- tation of death, which precedes and fucceeds them, and generally by a flow of pale urine; thefe convul- fions do not conftantly attend the hyfteric difeafe, but are occafionally fuperinduced by the difagreeable fen- fation arifing from the torpor or inverfion of a part of the alimentary canal. Whence the convulfion of laughter is frequently fufficient to reftrain thefe hyfteric pains, which accounts for the fits of laughter fre- quently attendant on this difeafe, M. M. To Class III. i. i.] OF VOLITION, 40* M. M. To remove the peculiar pain which- excites the convulfions. Venefeaion. An emetic. A ca- thartic with calomel. Warm-bath. Opium in large quantities, beginning with fmaller ones. Mercurial friaions. Efearicity. Cold-bath in the paroxyfm; or cold afperfion. See Memoirs of Med. Society, Lon. V. 3. p. 147. a paper by Dr. Currie. Convulfio debilis. The convulfions of dying animals, as of thofe which are bleeding to death in the flaugh- ter-houfe, are an effort to relieve painful fenfation, either of the wound which occafions their death, or of faintnefs from want of due diftention of the blood-vef- fels. Similar to this in a lefs degree is the fubfultus tendinum, or ftarting of the tendons, in fevers with debility ; thefe aaions of the mufcles are too weak to move the limb, but the belly of the aaing mufcles is feen to Swell, and the tendon to be ftretched. Thefe weak convulfions, as they are occafioned by the dif- agreeable fenfation of faintnefs from inanition, are fymptoms of great general debility, and thence fre- quently precede the general convulsions of the aa of dying. See a cafe of convulfion of a mufcle of the arm, and of the fore-arm, without moving the bones to which they were attached, Sea. XVII. i. 8. See twitchings of the face, Clafs IV. 3. 2. 2. 6. Convulfio dolorifica. Raphania. Painful con- vulfion. In this difeafe the mufcles of the arms and legs are exerted to relieve the pains left after the rheu- matifm in young and delicate people ; it recurs once or twice 4i» DISEASES [Class III. i. I.- twice a day, and has been miftaken for the chorea, or St. Vitus*s dance; but differs from it, as the undue motions in that difeafe only occur, when the patient endeavours to exert the natural ones; are not attended with pain ; and ceafe, when he lies down without trying to move : the chorea, or dance of St. Vitus, is ®ften introduced by the itch, this by the rheumatifm. It has alfo been improperly called nervous rheuma- tifm ; but is distinguished from rheumatifm, as the pains recur by periods once or twice a day ; whereas in the chronic rheumatifm they only occur on moving the affeaed mufcles. And by the warmth of a bed the pains of the chronic rheumatifm are increafed, as the mufcles or membranes then become more fenfible to the ftimulus of the extraneous mucaginous material deppfited under them. Whereas the pains of the ra- phania, or painful convulfions, commence with cold- nefs of the part, or of the extremities. See Rheumatif- mus chronicus, Clafs I. i. 3. 12. The pains which accompany the contraaions of the mufcles in this difeafe, feem to arife from the too great violence of thofe contraaions, as happens in the cramp of the calf of the leg ; from which they diifer in thofe being fixed, and thefe being reiterated Contraaions. Thus thefe convulfions are generally of the lower limbs, and recur at periodical times from fome uneafy fenfation from defea of aaion, like other periodic difeafes) and the convulfion? of the limbs relieve the original uneafy painful fenfation, and then produce a greater pain from their own too vehement contrac- tions. There is however another way of accounting for Class III. i. i.] OF VOLITION. 411 for thefe pains, when they fucceed the acute rheuma- tifm ; and that is by the coagulable lymph, which may be left ftill unabforbed on the membranes ; and which may be in too fmall quantity to affea them with pain in common mufcular exertions, but may produce great pain, when the bellies of the mufcles fwell to a larger bulk in violent aaion. M. M. Venefeaion. Calomel. Opium. Bark. One grain of calomel and one of opium for ten fuc- ceffive nights. A bandage fpread with emplaftrum de minio put tight oh the affeaed part. 7. Epilepfia is originally induced, like other convul- fions, by a voluntary exertion to relieve fome pain. This pain is moft frequently about the pit of the fto- mach, or termination of the bile-dua; and in fome cafes the torpor of the ftomach, which probably occa- fioned the epileptic fits, remains afterwards, and pro- duces a chronical anorexia ; of which a cafe is related in Clafs II. 2. 2. 1. There are inftances of its begin- ning in the heel, of which a cafe is publifhed by Dr. Short, in the Med. Effays, Edinb. I once faw a child about ten years old, who frequently fell down in convulfions, as flie was running about in play ; on examination a wart was found on one ancle, which was ragged and inflamed; which was direaed to be cut off, and the fits never recurred. When epilepfy firft commences, the patients are liable to utter one fcream before they fall down; afterwards the convulfions fo immediately follow the pain, 4'i DISEASES [Class III. r. t. pain, which occafions them, that the patient does not recolfea or feem fenfible of the preceding pain. Thus in laughter, when it is not exccffive, a perfon is not confcious of the pain, which fo often recurs, and caufe's the fucceffive fcreams or exertions of laughter, which give a temporary relief to it. Epileptic fits frequently recur in fleep from the in- creafe of fenfibility at*that time, explained in Sea. XVIII. 14. In two fuch cafes, both of young women, one grain of opium given at night, and continued many months, had fuccefs; in one of them the opium was omitted twice at different times, and the fit recurred on both the nights. In the more violent cafe, de- fcribed in Sea. XVIII. 15. opium had no effea. Epileptic fits generally commence with fetting the teeth, by which means the tongue is frequently wound- ed ; and with rolling the eye-balls in every kind of direaion ; for the mufcles which fufpend the jaw, as well as thofe which move the eyes, are in perpetual motion during our waking hours; and yet continue fubfervient to volition ; hence their more facile and forcible aaions for the purpofe of relieving pain by the exhauftion of fenforial power. See Sea. XXXIV. 1. 4. Epileptic convulfions are not attended with the fear of death, as in the hyfteric difeafe, and the urine is of a ftraw colour. However it muft be noted, that the difagreeable fenfations in hyfteric difeafes fometimes are the caufe of true epileptic convulfions, of fyncope, and of madnefs. The Class III. i. i.] OF VOLITION. 4r? The pain, which occafions fome fits of epilepfy, is felt for a time in a diftant part of the fyftem, as in a toe or heel; and is faid by the patient gradually to afcend to the head, before the general convulfions commence. This afcending fenfation has been called aura epileptica, and is faid to have been prevented from affeaing the head by a tight bandage round the limb. In this malady the pain* probably of fome tor- pid membrane, or difeafed tendon, is at firft only fo great as to induce flight fpafms of the mufcular fibres, in its vicinity; which flight fpafms ceafe on the numb- nefs introduced by a tight bandage ; when no bandage is applied, the pain gradually increafes, till generally convulfions are exerted to relieve it. The courfe of a lymphatic, as when poifonous matter is abforbed; or of a nerve, as in the fciatica, may, by the fympathy cxifting between their extremities and origins, give an idea of the afcent of an aura or vapour. In difficult parturition it fometimes happens, that general convulfions are excited to relieve the pain of labour, inftead of the exertions of thofe mufcles of the abdomen and diaphragm, which ought to forward the exclufion of the child.' See Clafs HI. i. i. That is. inftead of the particular mufcular aaions, which ought to be excited by fenfation to remove the offending caufe, general convulfions are produced by the power of volition, which ftill the pain, as in common epilepfy, without removing tlie caufe ; and, as the parturition is not thus promoted, the convulfions continue, till the fenforial power is totally exhaufted, that is, till death. 4'4 DISEASES [Class III. r. i.' death. In patients affliaed with epilepfy from other caufes, I have feen the moft violent convulfions recur frequently during pregnancy without mifcarriagc, as they did not tend to forward the exclufion of the fetus. M. M. Venefeaion. A large dofe of opium. De- livery. The later in life epileptic fits are firft experienced, the more dangerous they may be efteemed in general; as in thefe cafes the caufe has generally been acquired by the habits of the patient, or by the decay of fome part, and is thus probably in an increafing ftate. Whereas in children the changes in the fyftem, as they advance to puberty, fometimes remove the caufe. So in toothing, fits of convulfion with ftupor frequently occur, and ceafe when the tooth advances ; but this is not to be expeaed in advanced life. Sir------, about fixty years of age, had only three teeth left in his upper jaw, a canine tooth, and one on each fide of it. He was feized with epileptic fits, with pain commencing in thefe teeth. He was urged to have them extraaed, which he delayed too long, till the fits were become habitual, and then had them extraaed in vain, and in a few months funk under the difeafe. Mr. F----, who had lived intemperately, and had been occafionally affeaed with the gout, was fuddenly feized with epileptic fits ; the convulfions were fuc- ceeded by apopkaic fnoring ; from which he was, in about 20 minutes, difturbed by frefh convulsions, and had continued in this fituation above four-and-twenty hours. About eight ounces of blood were then taken from Class III. i. i.] OF VOLITION. 4t5 from him ; and after having obferved, that the apo- pfeaic's torpor continued about 20 minutes, I dire&ed him to be forcibly raifed up in bed, after he had thus Iain about fifteen minutes, to gain an interval between the termination of the fleep, and the renovation of convulfion. In this interval he was induced to fwal- low forty drops of laudanum. Twenty more were given him in the fame manner in about half an hour, both which evidently Shortened the convulfion fits, and the confequent ftupor ; he then took thirty more drops, which for the prefent removed the fits. He became rather infane the next day, and after about three more days loft the infanity, and recovered his ufual ftate of health. The cafe mentioned in Sea. XXVII. 2. where the patient was left after epileptic fits with a fuffufion of blood beneath the tunica adjunaiva of the eye, was in almoft every refpea fimilar to the preceding, and fubmitted to the fame treatment. Both of them fuf- fered frequent relapfes, which were relieved by the fame means, and at length perifhed, I believe, by the «pileptic fits. In thofe patients, who have not been fubjea to epi- lepfy before they have arrived to about forty years of age, and who have been intemperate in refpea to fpiri- tuous potation, I have been induced to believe, that the fits were occafioned by the pain of a difeafed liver ; and this became more probable in one of the above fubjeas, who had ufed means to repel eruptions en the face; and thus by fome Stimulant application 4 had 4>« DISEASES [Class III. i. i. had prevented an inflammation taking place on the fkin of the face inftead of on fome part of the liver. Secondly, as in thefe cafes infanity had repeatedly oc- curred, which could not be traced from an hereditary fource; there is reafon to believe, that this as well as the epileptic convulfions were caufed by fpirituous po- tation ; and that this therefore is the original fource both of epilepfy and of infanity in thofe families, which arc affliaed with them. This idea however brings fome confolation with it; as it may be inferred, that in a few fober generations thefe difeafes may be eradicated, which otherwife deftroy the family. M. M. Venefeaion. Opium. Bark. Steel. Ar- fenic. Opium one grain twice a day for years toge- ther. See the preceding article. 8. Epilepfia dolorifica. Painful epilepfy. In the common epilepfy the convulfions are immediately in- duced, as foon as the difagreeable fenfation, which caufes them, commences; but in this the pain conti- nues long with cold extremities, gradually increafing for two or three hours, till at length convulfions or madnefs come on; which terminate the daily parox- yfm, and ceafe themfelves in a little time afterwards. This difeafe fometimes originates from a pain about the lower edge of the liver, fometimes in the temple, and fometimes in the pudendum; it recurs daily for five or fix weeks, and then ceafes for feveral months. The pain is owing to defea of aaion, that is, to the accumulation of fenforial power in the part, which probably Class III. i. i.] OF VOLITION. 4*7 probably fympathizes With fome other part, as ex- plained in Sea. XXXV. 2. XII. 5. 3. and Clafs II. 1, 1. n. and IV. 2. 2. 3. It is the moft painful malady that human nature is liable to !—See Seel. XXXIV. 1. a. Mrs. C----- was feized every day about the fame hour with violent pain on the right fide of her bowels about the fituation of the lower edge of the liver, without fever, which increafed for an hour or two, till it became totally intolerable. After violent fcream- ing She fell into convulfions, which terminated fome- times in fainting, with or without ftertor, as in com- mon epilepfy; at other times a temporary infanity fupervened ; which continued about half an hour, and the fit ceafed. Thefe paroxyfms had returned daily for two or three weeks, and were at length removed by large dofes of opium, like the fits of reverie or fomnambulation. About half an hour be- fore the expeaed return of the fit three or four grains of opium were exhibited, and then tinaure of opium was given in warm brandy and water about 20 or 30 drops every half hour, till the eyes became fomcwhat inflamed, and the nofe began to itch, and by the fbarp movements of the patient, or quick fpeech, an evident intoxication appeared ; and then it generally happened that the pain ceafed. But the effeas of this large dofe of opium was fucceeded by perpetual ficknefs and efforts to vomit, with great general debility all the Succeeding dav. E c The 4*8 DISEASES [Class III. i. i. The rationale of this temporary cure from the ex- hibition of opium and vinous fpirit depends on the great expenditure of fenforial power in the increafed aaions of all the irritative motions, by the Stimulus of fuch large quantities of opium and vinous fpirit; together with the produaion of much fenfation, and many movements of the organs of fenfe or ideas in confequence of that fenfation ; and laftly, even the motions of the arterial fyftem become accelerated by this degree of intoxication, all which foon exhaufted fo much fenforial power as to relieve the pain; which would otherwife have caufed convulfions or infanity, which are other means of expending fenforial power. The general debility on the fucceeding day, and the particular debility of the ftomach, attended in con- fequence with ficknefs and frequent efforts to vomit, were occafioned by the fyftem having previoufly been fo Strongly ftimulated, and thofe parts in particular on which the opium and wine more immediately aaed. This ficknefs continued fo many hours as to break the catenation of motions, which had daily repro- duced the paroxyfm ; and thus it generally happened, that the whole difeafe ceafed for fome weeks or months from one great intoxication, a circumftance not eafily to be explained on any other theory. The excefs or defea of motion in any part of the fyftem occafions the produaion of pain in that part, as in Sea. XII. i. 6. This defea or excefs of fibrous aaion is generally induced by excefs or defea of the ftimulus of objects external to the moving organ. But there Class III. i. i.] OF VOLITION. 4*9 there is another fource of exceSfive fibrous aaion, and confequent pain, which is from excefs of volition, which is liable to affea thofe mufcles, that have weak antagonists; as thofe which fupport the under jaw, and clofe the mouth in biting, and thofe of the calf of the leg; which are thus liable to fixed or painful contraaions, as in trifmus, or locked jaw, and in the cramp of the calf of the leg ; and perhaps in fome colics, as in that of Japan : thefe pains, from contrac- tion arifing from excefs of volition in the part from the want of the counteraction of antagonist mufcles, may give occafional caufe to epileptic fits, and may be relieved in the fame way, either by exciting irri- tative and fenfitive motions by the ftimulus of opium and wine ; or by convulfions or infanity, as defcribed above, which are only different methods of exhaufting the general quantity of fenforial power. Confidering the great refemblance between this kind of painful epilepfy and the colic of Japan, as defcribed by Kemfer ; and that that difeafe was faid to be cured by acupunaure, or the prick of a needle ; "I directed fome very thin Steel needles to be made about three inches long, and of fuch a temper, that they would bend double rather than break ; and wrapped wax thread over about half an inch of the blunt end for a handle. One of thefe needles, when the pain occurred, was pufhed about an inch into the painful part, and the pain inftantly ceafed ; but I was not certain, whether the fear of the patient, or the ftimulus of the punaure, occafioned the ceffation of pain j and E e 2 as 4*o DISEASES [Class III. r. t. as the paroxyfm had continued feme weeks, and was then declining, the experiment was not tried again. The difeafe is faid to be very frequent in Japan, and its feat to be in the bowels, and that the acupunaurc eliminates the air, which is fuppofed to diftend the bowel. But though the aperture thus made is too fmall to admit of the eduaion of air ; yet as the ftimulus of fo fmall a punaure may either excite a torpid part into aaion, or caufe a fpafmodic one to ceafe to" aa; and laftly, as no injury could be likely to enfue from fo fmall a perforation, I fliould be inclined at fome future time to give this a fairer trial in fimilar circumftances. Another thin? wrorth trial at the commencement of this deplorable difeafe would be efearicity, by paffing ftrong Shocks through the painful part; which, whether the pain was owing to the inaaion of that part, or of fome other membrane affociated with it, might ftimu- late them into exertion ; or into inaaivity, if owing to fixed painful contraaion. And laftly, the cold bath, or afperfions with cold water on the affeaed part, according to the method of Dr. Currie in the memoirs of a Med. Soc. London, V. iii. p. 147, might produce great effea at the commencement of the pain. Neverthelcfs opium duly administered, fo as to precede the expeaed paroxyfm, and in fuch dofes, given by degrees, as to induce intoxication, is principally to be depended upon in this deplorable malady. To which fhould be added, that if venefeaion can be previoufly performed, even to Class III. i. i.} OF VOLITION. 4*« to but few ounces, the effea of the opium is much more certain; and ftill more fo, if there be time to premife a brilk cathartic, or even an emetic. The effea of increafed ftimulus is fo much greater after previous defea of Stimulus ; and this is ftill of greater advantage where the caufe of the difeafe happens to confift in a material, which can be abforbed. See Art. IV. 2. 8. M. M. Venefeaion. An emetic. A cathartic. Warm bath. Opium a grain every half hour. Wine. Spirit of wine. If the patient becomes intoxicated by the above means, the fit ceafes, and violent vomit- ings and debility fucceed on the fubfequent day, and prevent a return. Blifters or fmapifms on the fmall of the leg, taken off when they give much pain, are of ufe in Slighter convulfions. Acupunaure. Elec- tricity, Afperfion with cold water on the painful part. 9. Somnambulifmus. Sleep-walking is a part of reverie, or fludium in^ne, defcribed in Sea. XIX. In this malady the patients have only the general appearance of being afleep in refpea to their inatten- tion to the ftimulus of external objeas, but, like the epilepfies above defcribed, it confifts in voluntary exertions to relieve pain. The mufcles are fubfervient to the will, as appears by the patient's walking about, and fometimes doing the common offices of life. The ideas of the mind alfo are obedient to the will, becaufe their difcourfe is confident, though they ft c 3 anfwer *22 DISEASES [Class III. i. t. anfwer imaginary queftions. The irritative ideas of external objects continue in this malady, becaufe the patients do not run againft the furniture of the room ; a id when they apply their volition to their organs of fenfe, they become fenfible of the objeas they attend to, bur not otherwife, as general fenfation is deftroyed by the violence of their voluntary exertions. At the fame time the fenfations of pleafure in confequence of ideas excited by volition are vividly experienced, and other ideas feem to be excited by thefe pleafurable fenfations, as appears in the cafe of Mafter A. Sea. XXXIV. 3. 1. where a hiftory of a hunting fcene was voluntarily recalled, with all the pleafurable ideas which attended it. In melancholy madnefs the patient is employed in voluntarily exciting one idea, with thofe which are conneaed with jt by voluntary aflb- ciations only, but not fo violently as to exclude the Stimuli of external objeas. In reverie variety of ideas arc occafionally excited by volition, and thofe which are conneaed with them either by fenfitive or voluntary affociations, and that fo violently as to exclude the ftimuli of external objeas. Thefe two fituations of our fenfual motions, or ideas, refemble convulfion and epilepfy; as in the former the ftimulus of external objeas is ftill perceived, but not in the latter. Whence this difeafe, fo far from being conneaed with fleep, though it has by univerfal miftake acquired its name from it, arifes from excefs of volition', and not from a fufpenfion of it; and though, like other kinds of epilepfy, it often attacks the patients in their fleep, yet Class III. i. i.] OF VOLITION. 423 yet thofe two, whom I faw, were more frequently feized with it while awake, the fleep-walking being a part of the reverie. See Sea. XIX. and XXXIV. 3. and Clafs II. 1. 7. 4. and III. 1. 2. 18. M. M. Opium in large dofes before the expeaed paroxyfm. 10. Afthma convulfivum. Tlie fits of convulfive afthma return at periods, and are attended with cold extremitie , and fo far refemble the accefs of an intemittent fever ; but, as the lungs are not fenfible to die pain of cold, a Shivering does not fucceed, but inftead of it violent efforts of refpiration ; which have no tendency, as in the humoral afthma, to diflodge any offending material, but only to relieve the pain by exertion, like the fliuddering in the beginning of ague-fits, as explained Clafs III. 1. 1. 2. The infenfibility of the lungs to cold is obfervable on going into frofty air from a warm room; the hands and face become painfully cold, but no fuch fenfation is excited in the lungs; which is another argument in favour of the exiftence of a peculiar fet of nerves for the purpofe of perceiving the univerfal fluid matter of heat, in which all things are immerfed. See Sea. XIV. 6. Yet are the lungs nevertheless very fenfible to the deficiency of oxygen in the atmofphere, as all people experience, when they go into a room crowded with company and candles, and complain, that it is fo clofe, they can fiercely breathe ; and the Tame in fome hot days in fummer. ,. E e 4 There 424 DISEASES [Class III. i. '. There are two difeafes, which bear the name of afthma. The firft is the torpor or inability of the minute veffels of the lungs, confifting of the tcrmin?.- tions of the pulmonary and bronchi;.! arteries and veins, and their attendant lymphatics; in this circum- ftance it refembles the difficulty of breathing, which attends cold bathing. If this continues long, a con- gestion of fluid in the air-cells fucceeds, as the abforb- ent aaions ceafe completely before the fecerning ones; as explained in Clafs I. i. 2. 3. And the coldnefs, which attends the inaaion of thefe veffels, prevents the ufual quantity of exhalation, Some fits ceafe before this congestion takes place, and in them no violent fweating nor any expuition of phlegm occurs. This is the humoral afthma, defcribed at Clafs II. 1. 1. 7, The fecond kind of afthma confifts in the convulfive aaions in confequence of the difagreeable fenfations thus induced; which in fome fits of afthma are very great, as appears in the violent efforts to raife the ribs, and to deprefs the diaphragm, by lifting the Shoulders. Thefe, fo long as they contribute to remove the caufe of the difeafe, are not properly convulfions, but exertions immediately caufed by fen- fation ; but in this kind of afthma they are only efforts to relieve pain, and are frequently preceded by other epileptic convulsions.. Thefe two kinds of afihmas have fo many refem- bling features, and are fo frequently intermixed, that »t. often require £rcat attention to difliugulfli them; but Class III. i. i.J OF VOLITION. 42$ but as one of them is allied to anafarca, and the other to epilepfy, we fliall acquire a clearer idea of them by comparing them with thofe diforders. A criterion of the humoral or hydropic afthma is, that it is relieved by copious fweats about the head and breaft, which are to be aferibed to the fenfitive exer- tions of the pulmonary veffels to relieve the pain occafioned by the anafar.cous congestion in the air- cells ; and which is effeaed by the increafed abforption of the mucus, and its elimination by the retrograde aaion of thofe lymphatics of the Skin, whofe branches communicate with the pulmonary ones; and which partial fweats do not eafily admit of any other expla- nation. See Clafs I. 3. 2. 8. Another criterion of it is, that it is generally attended with fwelled legs, or other fymptoms of anafarca. A criterion of the con- vulfive afthma may be had from the abfence of thefe cold clammy fweats of the upper part of the body only, and from the patient having occafionally been fubjea to convulfions of the limbs, as in the common epilepfy. It may thus frequently happen, that in the humoral afthma fome exertions of the lungs may occur, which may not contribute to difcharge the anafarcous lymph, but may be efforts fimply to relieve pain ; befides thofe efforts, which produce the increafed abforption and elimination of it; and thus we have a bodily difeafe refembling in this circumftance the reverie, in which both fenfitive and voluntary motions are at the fame lime, or in fucccfllcn, excited for the purpofe of relieving pain. I- 425 DISEASES [Class III. i. i. It may likewlfe fometimes happen, that the dif- agreeable fenfation, occafioned by the congestion of lymph in the air-cells in the humoral or hydropic afthma, may induce voluntary convulfions of the refpi- ratory organs only to relieve the pain, without any fenfitive aaions of the pulmonary abforbents to abforb and eliminate the congeftion of ferous fluid ; and thus the fame caufe may occafionally induce either the humoral or convulfive afthma. The humoral afthma has but one remote caufe, which is the torpor of the pulmonary veffels, like that which occurs on going into the cold bath ; or the want of abforption of the pulmonary lympha- tics to take up the lymph effufed into the air-cell. Whereas the convulfive afthma, like other convulfions, or epilepfies, may be occafioned by pain in almoft any remote part of the fyftem. But in fome of the adult patients in this difeafe, as in many epilepfies, I have fufpeaed the remote caufe to be a pain of the liver, or of the biliary duas. The afthmas, which have been induced in confe- quence of the recefs of eruptions, efpecially of the leprous kind, countenance this opinion. One lady I knew, who for many years laboured under an afthma, which ceafed on her being affliaed with pain, fwelling, and diftortion of fome of her large joints, which were efteemed gouty, but perhaps erroneoufly. And a young man, whom I faw yefterday, was feized with afthma on the retroceffion, or ceafing of eruptions ©n his face. The Class III. i. i.] OF VOLITION. 427 The convulfive afthma, as well as the hydropic, are more liable to return in hot weather; which may be occafioned by the lefs quantity of oxygen existing in a given quantity of warm air, than of cold, which can be taken into the lungs at one infpiration. They are both moft liable to occur after the firft fleep, which is therefore a general criterion of afthma. The caufe of this is explained in Sea. XVIII. 15. and applies to both of them, as our fenfibility to internal uneafy fenfation increafes during fleep. When children are gaining teeth, long before they appear, the pain of the gums often induces convul- fions. This pain is relieved in fome by fobbing and fcreaming ; but in others a laborious refpiration is ex- erted to relieve the pain ; and this constitutes the true afthma convulfivum. In other children again general convulfions, or epileptic paroxyfms, are induced for this purpofe ; which, like other epilepfies, become eftablifhed by habit, and recur before the irritation has time to produce the painful fenfation, which ori- ginally caufed them. The afthma convulfivum is alfo fometimes induced by worms, or by acidity in the Stomachs of children, and by other painful fenfations in adults ; in whom it is -generally called nervous afthma, and is often joined with other epileptic fymptoms. This afthma is distinguished from the peripneumo- ny, and from the croup, by the pretence of fever in the two latter. It is diftinguiflied from the humoral .i.fthma, as in that the patients are more liable to run to 4^8 DISEASES [Cla from pains from excefs of ftimulus, which are gene* rally fucceeded by inflammation. But infanities are on the contrary generally induced by pains from ex- cefs of ftimulus, as from the too violent aaions of our ideas, as in common anger, which is an infanity of Short duration; for infanities generally, though not always, arife from pains of the organs of fenfe; but convulfions generally, though not always, from pains of the membranes or glands. And it has been previoufly explained, that though the membranes and glands, as the Stomach and Skin, receive great pain from want of ftimulus ; yet that the organs of fenfe, as the eye and ear, receive no pain from defea of ftimulus. Hence it follows, that the constitutions moft liable to convulfion, are thofe which moft readily become torpid in fome part of the fyftem, that is, which pof- fefs lefs irritability ; and that thofe moft liable to in- fanity, arc fuch as have excefs of fenfibility; and laftly, that thefe two circumftances generally exift is the fame conftitution ; as explained in Sea^XXXI. 2. on Temperaments. Thefe obfervations explain why epilepfy and infanity frequently fucceed or reciprocate with each other, and why inirritable habits, as fcro- phulous ones, are liable to infanity, of which I have known fome inftances. In many cafes however there is no appearance of the difpofition to epilepfy or infanity of the parent being tranfmitted to the progeny. Firft, where the mfanity has arifen from fome violent difappointment, and 44* DISEASES [Class III. i. 2. and not from intemperance in the ufe of fpirituous liquors. Secondly, where the parent has acquired the infanity or epilepfy by habits of intoxication after the procreation of his children. Which habits I fup- pofe to be the general caufe of the difpofition to in- fanity in this country. See Clafs III. i. i. 7. As the difpofition to gout, dropfy, epilepfy, and infanity, appears to be produced by the intemperate ufe of fpirituous potation, and is In all of them here- ditary ; it feems probable, that this difpofition gradu- ally increafes from generation to generation, in thofe families which continue for many generations to be intemperate in this refpea ; till at length thefe difeafes are produced; that is, the irritability of the fyftem gradually is decreafed by this powerful Stimulus, and the fenfibility at the fame time increafed, as explained in Seft. XXXI. 1. and 2. This difpofition is com- municated to the progeny, and becomes ftill increafed, if the fame ftimulus be continued, and fo on by a third and fourth generation; which accounts for the appearance of epilepfy in the children of fome fami- lies, where it was never known before to have exifted, and could not be aferibed to their own intemperance. A parity of reafoning fliews, that a few fober genera- tions may gradually in the fame manner reftore a due degree of irritability to the family, and decreafe the excefs of fenfibility. From hence it would appear probable, that fcro- phula and dropfy are difeafes from inirritability; but that in epilepfy and infanity an excefs of fen- fibility Class III. i. 2.] OF VOLITION. 447 Ability is added, and the two faulty temperaments are thus conjoined. SPECIES. 1. Mania mutabilis. Mutable madnefs. Where the patients are liable to miftake ideas of fenfation for thofe from irritation, that is, imaginations for reali- ties, if cured of one fource of infanity, they are liable in a few months to find another fource in fome new miftaken or imaginary idea, and to aa from this new idea. The idea belongs to delirium, when it is an imaginary or miftaken one; but it is the voluntary aaions exerted in confequence of this miftaken idea, which conftitute infanity. In this difeafe the patient is liable carefully to con- ceal the objea of his defire or averfion. But a con- ftant inordinate fufpicion of all people, and a careleiE- nefs of cleanlinefs, and of decency, are generally con- comitants of madnefs. Their defigns cannot be coun- teraaed, till you can investigate the delirious idea or objea of their infanity ; but as they are generally timid, they are therefore lefs to be dreaded. Z. Z. called a young girl, one of his maid-fervants, into the parlour, and, with cocked piftols in his hands, ordered her to Strip herfelf naked; he then infpeaed her with fome attention, and difmiffed her untouched. Then he Stripped two of his male fer- vants in the fame manner, to the great terror of the neighbourhood. After he was fecured, with much difficulty he was perfuaded to tell me, that he had got the 44* DISEASES [Class III. i. z. the itch, and had examined fome of his fervants to find out from whom he had received it; though at the fame time there was not a fpot to be feen on his hands, or other parts. The outrages in confequence of this falfe idea were in fome meafure to be aferibed to the pride occafioned by unreftrained education, affluent wealth, and dignified family. Madnefs is fometimes produced by bodily pain, particularly I believe of a difeafed liver, like convul- fion and epilepfy ; at other times it is caufed by very painful ideas occafioned by external circumftances, as of grief or difappolntment; but the moft frequent caufe of infanity arifes from the pain of fome imaginary or miftaken idea ; which may be termed hallucinatio maniacalis. This hallucination of one of the fenfes is often produced in an inftant, and generally becomes gradually weakened in procefs of time, by the perpe- tual ftimulus of external objeas, or by the fucceffions of other catenations of ideas, or by the operations of medicines; and when the maniacal hallucination ceafes, or is forgotten, the violent exertions ceafe, which were in confequence of it, and the difeafe is cured. Mr.----, a clergyman, about forty years of age, who was rather a weak man, happened to be drinking wine in jocular company, and by accident fwallowed a part of the feal of a letter, which he had juft then received; one of his companions feeing him alarmed, cried out in humour, " It will feal your bowels up." He became melancholy from that inftant, and in a day or two refuted to fwallow any kind of nourifhment. 4 On Class III. i. 2.] OF VOLITION. 449 On being preffed to give a reafon for this refufal, he anfwered, he knew nothing would pafs through him. A cathartic was given, which produced a great many evacuations, but he ftill perfifted, that nothing paffed through him ; and though he was frightened into tak- ing a little broth once or twice by threats, yet he foon ceafed intirely to fwallow any thing, and died in con- fequence of this infane idea. Mifs-----, a fenfible and ingenious lady, about thirty, faid flie had feen an angel; who told her, that She need not eat, though all others were under the neceffity of Supporting their earthly exiftence by food. After fruitlefs perfuafions to take food, flie Starved herfelf to death.—It was propofed to fend an angel of an higher order ro tell her, that now flie muft begin to eat and drink again; but it was not put into execution. Mrs.-----, a lady between forty and fifty years of age, imagined that fhe heard a voice fay to her one day, as She was at her toilet, " Repent, or you will " be damned." From that moment fhe became me- lancholy, and this hallucination affeaed her in greater or lefs degree for about two years ; flie then recovered perfeaiy, and is now a cheerful old woman. Mrs.-----, a farmer's wife, going up flairs to drefs, found the curtains of her bed drawn, and on undrawing them, flie believed that fhe faw the corps of her fifter, who was then ill at the diftance of twenty miles, and became from that time infane ; and as her fifter died about the time, flie could not be G g produced 450 DISEASES [Class III. i. z. produced to counteraa the infane hallucination, but She perfeaiy recovered in a few months. Mrs.-----, a moft elegant, beautiful, and accom- plished lady, about twenty-two* years of age, had been married about two months to an elegant, po- lhlied, and affluent young man, and it was well known to be a love-march, on both fides. She fuddenly be- came melancholy, and yet not to fo great a degree, but that flie could command herfelf to do the honours of her table with' grace and apparent cafe. After- many days intreaty, fhe at length told mer that flie thought her marrying her huiband' had made him un- happy ; and that this idea flic could not efface from her mind day or night. I withstood her being con- fined, as fome had advifed, and propofed a fea-voyage to her, with expeaation that the ficknefs, as well as change of objeas, might remove the infane halluci- nation, by introducing other energetic ideas; this was not complied with, but flie travelled about Eng- land with her friends and her huiband for many months, and at length perfeaiy recovered, and is now I am informed in health and fpirits. Thefe cafes are related to Shew the utility of en- deavouring to investigate the maniacal idea, or hallu- cination ; as it may not only acquaint us with the probable defigns of the patient, from whence may be deduced the neceffity of confinement; but alfo may fome time lead to the moft effeaual plan of cure. I received good information of the truth of the following cafe, which was publifhed a few years. ago*. Class III. i. 2.] OF VOLITION. 45i ago in the newfpapers. A young farmer in War- wickshire, finding his hedges broke, and the Sticks carried away during a frofty feafon, determined to watch for the thief. He lay many cold hours under a hay-flack, and at length an old woman, like a witch in a play, approached, and began to pull up the hedge; he waited till fhe had tied up her bottle of flicks, and was carrying them off, that he might con via her of the theft, and then fpringing from his concealment, he feized his prey with violent threats. After fome altercation, in which her load was left upon the ground, She kneeled upon her bottle of Slicks, and raifing her] arms to heaven beneath the bright moon then at the full, fpoke to the farmer al- ready fhivering. with cold, " Heaven grant, that thou never mayeft know again the bleffing to be warm." He complained of cold all the next day, and wore an upper coat, and in a few days another, and in a fortnight took to his bed, always faying nothing made him warm, he covered himfelf with very many blankets, and had a fieve over his face, as he lay ; and from this one infane idea he kept his bed above twenty years for fear of the cold air, till at length he died. M. M. As mania arifes from pain either of our mufcles or organs of fenfe, the arts of relieving pain muft constitute the method of cure. See Sea. XXXIV. 3. 4. Venefeaion. Vomits of from five grains to ten of emetic tartar, repeated every third morning for three or four times ; with folution of gum-ammoniac, G g 2 and 452 DISEASES [Class III. i. 2. and foluble tartar, fo as to purge gently every day. Afterwards warm bath for two or three hours a day Opium in large dofes. Bark. Steel. Dr. Binns gave two feruples (40 grains) of folid opium at a dofe, and twenty grains four hours after- wards ; which reftored the patient. Dr. Brandreth gave 400 drops of laudanum to a maniac in the great- eft poffible furor, and in a few hours he became calm and rational. Med. Comment, for 1791, p. 384. Prognoftic. The temporary quick pulfe attending fome ma- niacal cafes is fimply a fymptom of debility, and is the confequence of too great exertions; but a permanent quick pulfe fhews the pretence of fever, and is fre- quently a falutary fign ; becaufe, if the life of the patient be fafe, when the fever ceafes, the infanity generally vanishes along with it, as mentioned above. In this cafe the kind of fever muft direa the method of curing the infanity ; which muft confift of moderate evacuations and diluents, if the pulfe be ftrong; or by nutrientia, bark, and fmall dofes of opium, if the pulfe be weak. Where the caufe is of a temporary nature, as in puerperal infanity, there is reafon to hope, that the difeafe will ceafe, when the bruifes, or other painful fenfations attending this ftate, are removed. In thefe cafes the child fliould be brought frequently to the mother, and applied to her breaft, if She will fuffer it, and this whether flie at firft attends to it or not; Class III. i. 2.] OF VOLITION. 45J as by a few trials it frequently excites the ftorge, or maternal affeaion, and removes the infanity, as I have witneffed. When the madnefs is occafioned by pain of the teeth, which I believe is no uncommon cafe, thefe muft be extraaed ; and the cure follows the extlnaion of the pain. There is however fome difficulty in deteaing the delinquent tooth in this cafe, as in hemi- crania, unlets by its apparent decay, or by fome pre- vious information of its pain having been complained of; becaufe the pain of the tooth ceafes, as foon as the exertions of infanity commence. When a perfon becomes infane, who has a family of fmall children to folicit his attention, the prognoftic is very unfavourable ; as it fliews the maniacal hallu- cination to be more powerful than thofe ideas which generally intereft us the moft. 2. Studium inane. Reverie coafifts of violent vo- luntary exertions of ideas to relieve pain, with all the trains or tribes conneaed with them by fenfations or affociations. It frequently alternates with epileptic convulfions; with which it correfponds, in refpea to the infenfibility of the mind to the ftimuli of external objects, in the fame manner as madnefs correfponds with common convulfion, in the patient's poffeffing at the fame time a fenfibility of the ftimuli of external objeas. Some have been reported to have been involved in reverie fo perfeaiy, as not to have been difturbed Gg3 by 454 DISEASES [Class III. i. 2. by the difcharge of a cannon ; and others to have been infenfible to torture, as the martyrs for religious opi- nions ; but thefe feem more properly to belong to par- ticular infanities than to reverie, like noftalgia and erotomania. Reverie is distinguished from madnefs as defcribed above; and from delirium, becaufe the trains of ideas are kept confiftent by the power of volition, as the perfon reafons and deliberates in it. Somnambu- lifmus is a part of reverie, the latter confifting in the exertions of the locomotive mufcles, and the former of the exertions of the organs of fenfe ; fee Clafs I. 1. 1. 9. and Sea. XIX. both which are mixed, or alter- nate with each other, for the purpofe of relieving pain. When the patients in reverie exert their volition on their organs of fenfe, they can occafionally perceive the ftimuli of external objeas, as explained in Sea. XIX. And in this cafe it refembles fometimes an hallucination of the fenfes, as there is a mixture of faa and imagination in their difcourfe ; but may be thus diftinguifhed: hallucinations of the fenfes are allied to delirium, and are attended generally with quick pulfe, and other fymptoms of great debility ; but reverie is without fever, and generally alternates with convulfions; and fo much intuitive analogy (fee Sea. XVII. 3. 7.) is retained in its paroxyfms, as to preferve a confiftency in the trains of ideas. Mifs G-----, whofe cafe is related in Sea. III. 5. 8. faid, as I once fat by her, " My head is fallen off, fee Class III. i. 2.] OF VOLITION. 45-5 fee it is rolled to that corner of the room, and the little black dog is nibbling the nofe off." On my walking to the place which flie looked at, and re- turning, and affuring her that her nofe was unhurt, flie became pacified, though I was doubtful whether fhe attended to me. See Clafs III. 1. 1. 9. and Clafs III. 1. 2. 2. M. M. Large dofes of opium given before the expeaed paroxyfm, as in epilepfia dolorifica, Clafs 411. 1.1. 8. The hallucinatio ftudiofa, or falfe ideas in reverie, differ from maniacal hallucinations above defcribed, as no infane exertions fucceed, and in the patients whom I have feen they have always been totally for- gotten, when the paroxyfm was over. Matter-----, a fchool-boy about twelve years old, after he came out of a convullion fit and fat up in bed, faid to me, " Don't you fee my father ftanding at the feet of the bed, he is come a long way on foot to fee me." I anfwered, no : " What colour is his coat?" He replied, " A drab colour." " And what buttons ?" " Metal ones," he anfwered, and added, " how fadly his legs are fwelled." In a few minutes he faid, with apparent furprife, " He is gone," and returned to his perfea mind. Other cafes are related in Sea. XIX. and XXXIV. 3. and in Clafs III. 1.2. 2. with further obfervations on this kind of hallucination ; which however is not the caufe of re- verie, but constitutes a part of it, the caufe being generally fome uneafy fenfation of the body. G g a 3. Vigilic. 456 DISEASES [Class III. 1.2. 3. Vigilia. Watchfulnefs confifts in the unceafmg exertion of volition; which is. generally caufed by fome degree of pain either of mind or of body, or from defea of the ufual quantity of pleafurable fenfa- tion ; hence if thofe, who are accuftomed to wine at night, take tea inftead, they cannot fleep. The fame happens from want of folid food for fupper, to thofe who are accuftomed to ufe it; as in thefe cafes there is pain or defea of pleafure in the ftomach. Sometimes the anxiety about fleeping, that is the defire to fleep, prevents fleep ; which confifts in an abolition of defire or will. This may fo far be com- pared to the impediment of fpeech defcribed in Sea. XVII. 1. 10. as the inteference of the will prevents the effea defired. Another fource of watchfulnefs may be from the too great fecretion of fenforial power in the brain, as in phrenzy, and as fometimes happens from the ex- hibition of opium, and of wine ; if the exhauftion of fenforial power by the general aaions of the fyftem occafioned by the ftimulus of thefe drugs can be fuppofed to be lefs than the increafed fecretion of it. * M. M. 1. Solid food to fupper. Wine. Opium. Warm bath. 2. The patient fliould be told that his want of Sleep is of no confequence to his health. 3. Venefeaion by cupping. Abstinence from wine. 4. A Iplifter by flimulating the Skin, and rhubarb by ftimulating the bowels, will fomeimes induce Sleep. Exercife. An uniform found, as of a paufing drop of Cluss III. i. 2.] CF VOLITION 457 of water, or the murmur of be^s. Other means are defcribed in Sea. XVIII. 20. 4. Erotomania. Sentimental love. Defcribed in its excefs by romance-writers and poets. As the ob- jea of love is beauty, and as our perception of beauty confifts in a recognition by the fenfe of vifion of thofe objeas, which have before infpired our love, by the pleafure they have afforded to many of our fenfes (Sea. XVI. 6.) ; and as brute animals have lefs accu- racy of their fenfe of vifion than mankind (ib.J ; we fee the reafon why this kind of love is not frequently obfervable in the brute creation, except perhaps in fome married birds, or in the aSfeaion of the mother to her offspring. Men, who have not had leifure to cultivate their tafte for vifible objeas, and who have not read the works of poets and romance-writers, are lefs liable to fentimental love; and as ladies are edu- cated rather with an idea of being chofen, than of choofing ; there are many men, and more women, who have not much of this infanity ; and are therefore more eafily induced to marry for convenience or in- terest, or from the flattery of one fex to the other. In its fortunate gratification fentimental love is fup- pofed to fupply the pureft fource of human felicity ; and from the fuddennefs with which many of thofe patients, defcribed in Species I. of this genus, were feized with the maniacal hallucination, there is reafon to believe, that the moft violent fentimental love may be acquired in a moment of time, as reprc- SenieJ 45-3 DISEASES [Qlass I'll. i. 2. fented by Shakefpear in the beginning of his Romeo and Juliet. Some have endeavoured to make a diftinaion be- tween beauty and grace, and have made them as it were rivals for the poffeffion of the human heart} but grace may be defined beauty in action ; for a fleeping beauty cannot be called graceful in whatever attitude fhe may recline; the mufcles muft be in aaion to produce a graceful attitude, and the limbs to produce a graceful motion. But though the objea of love is beauty, yet the idea is neverthelefs much enhanced by the imagination of the lover ; which appears from this curious circumftance, that the lady of his paSfion feldom appears fo beautiful to the lover after a few months feparation, as his ideas had painted her in his abfence ; and there is, on that account, always a little difappointment felt for a minute at their next interview from this hallucination of his ideas. This paffion of love produces reverie in its firft flate, which exertion alleviates the pain of it, and by the affiftance of hope converts it into pleafure. Then the lover feeks folitude, left this agreeable reverie Should be interrupted by external ftimuli, as defcribed by Virgil. ^ Tantum inter denfas, umbrofa cacumina, fagos Adidue veniebat, ibi haec incondita iblus Montibus et fylvis Sludio jaftabat inani. When the pain of love is fo great, as not to be re- lieved by the exertions of reverie, as above defcribed ; as when it is mifplaced on an objea, of which the lover y Class III. i. 2.] OF VOLITION. 459 lover cannot poffefs himfelf; it may ftill be counter- aaed or conquered by the Stoic philofophy, which Strips all things of their ornaments, and inculcates " nil admirari." Of which leffons may be found in the meditations of Marcus Antoninus. The maniacal idea is faid in fome lovers to have been weakened by the aaion of other very energetic ideas; fuch as have been occafioned by the death of his favourite child, or by the burning of his houfc, or by his being Ship- wrecked. In thofe cafes the violence of the new idea for a while expends fo much feaforial power as to prevent the exertion of the maniacal one; and new catenations fucceed. On this theory the lover's leap, fo celebrated by poets, might effea a cure, if the pa- tient efcaped with life. The third ftage of this difeafe I fuppofe is irreme- diable ; when a lover has previoufly been much en- couraged, and at length meets with negfea or difdain; the maniacal idea is fo painful as not to be for a mo- ment relievable by the exertions of reverie, but is inftantly followed by furious or melancholy infanity; and filicide, or revenge, have frequently been the con- fequence. As was lately exemplified in Mr. Hack- man, who fhot Mifs Ray in the lobby of the play- houfe. So the poet defcribes the paffion of Dido, _________----Moriamur inultse ?— At moriamur, ait,—fie, fie, javat ire fub umbras ! The Story of Medsea feems to have been contrived by Ovid, who was a good judge of the fubjea, to re- prefent the favage madnefs occafioned by ill-requited love. Thus the poet, Earth DISEASES [Class III. r. 2. Earth has no rage like love to hatred turn'd, Nor hell a fury like a woman fcom'd. Dryden. 5. Amorfui. Vanity confifts of an agreeable reve- rie, and is well ridiculed in the Story of Narciffus, who fo long contemplated his own beautiful image in the water, that he died from neglect, of taking fuf- tenance. I once faw a handfomc young man, who had been fo much flattered by his parents, that his vanity rofe fo near to infanity, that one might difcern by his perpetual attention to himfelf, and the difficulty with which he arranged his conversation, that the idea of himfelf intruded itfelf at every comma or paufe of his difcourfe. In this degree vanity muft afford great pleafure to the polfeffor ; and when it exifts within moderate bounds, may contribute much to the happi- nefs of focial life. My friend Mr.-----once complained to me, that he was much troubled with baflifulnefs in company, and believed that it arofe from his want of perfonal vanity; on this account he determined on a journey to Paris, when Paris was the centre of politenefs ; he there learnt to drefs, to dance, and to move his hands gracefully in converfation ; and returned a moft con- fummate coxcomb. But after a very few years he relapfed into rufticity of drefs and manners. M* M. The cure of vanity may be attempted by excefs of flattery, which will at length appear ridicu- lous, or by its familiarity will ceafe to be defired. I remember to have heard a ftory of a nobleman in the court Class III. i. 2.] OP VOLITION. 4S1 court of France, when France had a court, who was fo difagreeably vain in converfation, that the king was pleated to direa his cure, which was thus performed, Two gentlemen were direaed always to attend him, one was to ftand behind his chair, and the other at a refpeaful diftance before him ; whenever his lordfhip began to fpeak, one of them always pronounced, " Lord Gallimaufre is going to fay the beft thing in the world." And, as foon as his lordfhip had done Speaking, the other attendant pronounced, " Lord Gallimaufre has fpoken the beft thing in the world." Till in a few weeks this nobie lord was fo difgufted with praife that he ceafed to be vain; and his majefty difmiffed his keepers. 6. Noftalgia. Maladie de Pais. Calenture. An unconquerable defire of returning to one's native country, frequent in long voyages, in which the pa- tients become fo infane as to throw themfelves into the fea, mistaking it for green fields or meadows. The Swifs are faid to be particularly liable to this difeafe, and when taken into foreign fervice frequently to ce- fert from this caufe, and efpecially after hearing or finging a particular tune, which was ufed in their vil- lage dances, in their native country, on which account the playing or finging this tune was forbid by the pu- nifhment of death. Zwingerus. Dear is that flied, to which his foul conforms, And ilea) that hill, which lifts him to the dorms. Golds m 1 t w. 462 DISEASES [Class III. 1.2. 7. Spes religiofa. Superfluous hope. This mania- cal hallucination in its milder ftate produces, like fen- timental love, an agreeable reverie ; but when joined with works of fupererogation, it has occafioned many enormities. In India devotees confign themfelves by vows to moft painful and unceafing tortures, fuch as holding up their hands, till they cannot retraa them ; hanging up by hooks put into the thick Skin over their Shoulders, fitting upon Sharp points, and other felf torments. While in our part of the globe falling and mortification, as flagellation, has been believed to pleafe a merciful deity ! The ferenity, with which many have fuffered cruel martyrdoms, is to be aferibed to this powerful reverie. Mr.-----, a clergyman, formerly of this neighbour- hood, began to bruife and wound himfelf for the fake of religious mortification, and paffed much time in prayer, and continued whole nights alone in the church. As he had a wife and family of fmall chil- dren, I believed the cafe to be incurable ; as otherwife the affeaion and employment in his family conneaions would have oppofed the beginning of this infanity. He was taken to a madhoufe without effea, and after he returned home, continued to beat and bruife him- felf, and by this kind of mortification, and by fome- times long faffing, he at length became emaciated and died. I once told him in converfation, that " God was a merciful being, and could not delight in cruelty, but that I fuppofed he worshipped the devil." He was ftruck with this idea, and promifed me not to beat Class III. i. 2 ] OF VOLITION. 465 beat himfelf for three days, and I believe kept his word for one day. If this idea had been frequently forced on his mind, it might probably have been of fervice. When thefe works of fupererogation have been of a public nature, what cruelties, murders, maffacres, has not this infanity introduced into the world!—A commander, who had been very aaive in leading and encouraging the bloody deeds of St. Bartholomew^ day at Paris, on confeffing his fins to a worthy eccle- fiaftic on his death-bed, was afked, "Have you no- thing to fay about St. Bartholomew ?" " On that day," he replied, " God Almighty was obliged to me !"—The fear of hell is another infanity, which will be fpoken of below. 8. Superbia ftemmatis. Pride of family has fre- quently formed a maniacal hallucination, which in its mild ftate has eonfifted in agreeable reverie, but when it has been fo painful as to demand homage from others, it has frequently induced infane exertions. This infanity feems to have exifted in the flourishing ftate of Rome, as now all over Germany, and is at- tacked by Juvenal with great feverity, a fmall part of which I fliall here give as a method of cure.. Sat. 8. Say, what avails the pedigree, that brings Thy boafted line from hemes or from kings ; Though m my a mighty lord, in parchment roll'd, Name after name, thy coxcomb hands unfold ; Though wreathed patiiots crowd thy marble hall;, Or fteel clad warriors frown along the walls; Wl.i'e 4^4 DISEASES* [Class III. t. t While on broad canvas in the gilded frame All virtues flourilh, and all glories flame ?— S.iy,—if ere noon with idiot laugh you W-t Wallowing in wine, or cog the dubious die, Or act unfhamed, by each indignant bud, The midnight orgies of promifcuous lull !---- Go, lead mankind to Virtue's holy fhrine, With morals mend them, and with arts refine, Or lift, with golden characters unfurl'd, The flag of peace, and ftill a warring woild !— —So Shall with pious hands immortal Fame Wreathe all her laurels round thy honour'd name, High o'er thy tomb, with chill'd bold engrave, *• The truly noble are the good and brave." 9. Ambitio. Inordinate defire of fame. A care- leflhefs about the opinions of others is faid by Xeno- phon to be the fource of impudence ; certainly a pro- per regard for what others think of us frequently incites us to virtuous aaions, and deters us from vici- ous ones; and increafes our happinefs by enlarging our fphere of fympathy, and by flattering our vanity. Abftract what others feel, what others think, All pleafures ficken, and all glories fink. Pope. When this reverie of ambition excites to conquer nations, or to enflave them, it has been the fource of innumerable wars, and the occafion of a great devasta- tion of mankind. Cnefar is reported to have boafled, that he had deftroyed three millions of his enemies, and one million of his friends. 4 The Class III. i. 2.3 OF VOLITION. 465 The works of Homer are fuppofed to have done great injury to mankind by infpiring the love of mili- tary glory. Alexander was faid to fleep with them always on his pillow. How like a mad butcher amid a flock of flieep appears the hero of the Iliad, in the following fine lines of Mr. Pope, which conclude the twentieth book. His fiery courfers, as the chariot rolls, Tread down whole ranks, and crufh out heroes' fouls 3 DaSh'd from their hoofs, as o'er the dead they fly, Black bloody drops the fmoaking chariot dye ;— The fpiky wheels through heaps of carnage tore, And thick the groaning axles dropp'd with gore; High o'er the fcene of death Achilles flood, All grim with duft, all horrible with blood ; Yet ftill infatiate, ftill with rage on flame, Such is the lull of never dying fame ! The cure muft be taken from moral writers. Woolafton fays, Caefar conquered Pompey ; that is, a man whofe name confuted of the letters C. a?, f. a. r. conquered a long time ago a man, whofe name con- fifted of the letters P. o. m. p. e. y. and that this is all that remains of either of them. Juvenal alfo attacks this mode of infanity, Sat X. 166. —I, demens, et fasvas curre per alpes, Ut pueris placeas, et declamatio fias ! Which is thus translated by Dr. Johnfon, And left a name, at which the world grew pale, To point a moral, or adorn a tale ! H h 10. Marcr. 466 DISEASES [Class III. i. z. lOr Maror* Grief. A perpetual voluntary con- templation of all the circumftances of fome great lots.* as of a favourite child. In general the painful ideas gradually decreafe in energy, and at length the recol- feaion becomes more tender and lefs painful. The letter of Sulpicius to Cicero ©n the lofs of his daugh- ter is ingenious. The example of David on the lofs of his child is heroic. A widow lady was left in narrow circumftances with a boy and a girl, two beautiful and lively chil- dren, the one fix and tlie other feven years of age ; as her circumftances allowed her to keep but one maid-fervant, thefe two children were the fole atten- tion, employment, and confolation of her life; She fed them, dreffed them, Slept with them, and taught them herfelf; they were both fnatched from her by the gangrenous fore throat in one wreek : fo that flie loft at once all that employed her, as well as all that was dear to her. For the firft three or four days after their death, when any friend vilited her, She fat up- right, with her eyes wide open, without Shedding tears, and affeaed to fpeak of indifferent things. Afterwards flie began to weep much, and for fome weeks talked to her friends of nothing elfe but her dear children. But did not for many years, even to her dying hour, get quite over a gloom, which was left upon her countenance. In violent grief, uhen tears flow, it is efteemed a good fymptom ; becaufe then the aaions caufed by U-nfitive affociation take the place of thofe caufed by volition ; Class III. t. 2.] OF VOLITION. 467 Volition ; that is, they prevent the voluntary exer- tions of ideas, or mufcular aaions, which conftitutc infanity. The fobbing and fighing attendant upon grief are not convulfive movements, they are occafioned by the fenforial power being fo expended on the painful ideas, and their conneaions, that the perfon negfeas to breathe for a time, and then a violent figh or fob is neceffary to carry on the blood, which oppreffes the pulmonary veffels, which is then performed by deep or quick infpirations, and laborious expirations. Sometimes neverthelefs the breath is probably for a while voluntarily held, as an effort to relieve pain. The palenefs and ill health occafioned by long grief is fpoken of in Clafs IV. 2. 1. 9. The melioration of grief by time, and its being at length even attended with pleafure, depends on our retaining a diftina idea of the loft objea, and, for- getting for a time the idea of the lofs of it. This pleafure of grief is beautifully defcribed by Akenfide* Pleafures of Imagination, Book II. 1. 680. -------------Afk the faithful youth, Why the cold urn of her, whom long he loved, So often fills his arms ; fo often draws His lonely footfteps at the filent hour To pay the mournful tribute of his tears ? Oh ! he will tell thee, that the wealth of worlds Should ne'er feduce his bofom to forego That facred hour ; when, ftealing from the noife Of care and envy, fweet remembrance foothes With Virtue's kindeft looks his aching breaft, And turns his tears to rapture. H h 2 M. M. Con- +6R DISEASES [Class III. x. 2. M. M. Confolation is beft fupplied by the Christian doarine of a happy immortality. In the pagan re- ligion the power of dying was, the great confolation in irremediable diftrefs. Seneca fays, " no one need be unhappy unlets by his own fault." And the author of Tclemachus begins his work by faying, that Calypfo could not confole herfelf for the lofs of Ulyffes, and found herfelf unhappy in being immortal. In the firft hours of grief the methods of confolation ufed by uncle Toby, in Triftram Shandy, is probably the beft ; "he fat down in an arm chair by the bed of his diftreffed friend, and faid nothing." 11. TaJ'unn vita. The inanity of fubhmary things has afforded a theme to philofophers, moralists, and divines, from the earlieft records of antiquity ; " Vanity of vanities!" fays the preacher, " all is vanity !" Nor is there any one, I fuppofe, who has paffed the meridian of life, who has not at fome moments felt the nihility of all thing,-,. Wearinefs of life in its moderate degree has been efteemed a revive to aaion by fome philofophers. See Sea. XXXIV. 2. 3. But in thofe men, who have run through the ufual amufements of life early in refpea to their age; and who have not induftry or ability to cultivate thofe fcicnces, which afford a perpetual fund of novelty, and of confequent enter- tainment, are liable to become tired of life, as they fuppofe there is nothing new to be found in it, that can afford them pleafure ; like Alexander who is faid +0 Class III. i. 2.] OF VOLITION. 4$9 to have flied tears, becaufe he had not another world to conquer. Mr. —----» a gentleman about fifty, of polifhed manners, who in a few months afterwards deftroyed himfelf, faid to me one day, " a ride out in the morning, and a warm parlour and a pack of cards in the afternoon, is all that life affords." He was per- fuaded to have an iffue on the top of his head, as he complained of a dull head-ach, which being un- skilfully managed, deftroyed the pericranium to the fize of an inch in diameter; during the time this took in healing, he was indignant about it, and endured life, but foon afterwards fhot himfelf. Mr.----, a gentleman of Gray's Inn, fome years ago was prevailed upon by his friends to difmifs a miflrefs, by whom he had a child, but who was fo o-reat a termagant and feold, that flie was believed to ufe him very ill, and even to beat him. He became melancholy in two days from the want of his ufual ftimulus to aaion, and cut his throat on the third So completely, that he died immediately. Mr. Anfon, the brother of the late Lord Anfon, related to me the following anecdote of the death of L0rd Sc----. His Lordfhip font to fee Mr. Anfon on the Monday preceding his death, and faid, " You are the only friend I value in the world, I determined therefore to acquaint you, that I am tired of the infipidity of life, and intend to-morrow to leave it." Mr. Anfon faid, after much converfation, that he was obliged to leave town til! Friday, and added, H h 3 " As 47® DISEASES [Class III. i. z. *' As you profefs a friendship for me, do me this laft favour, I entreat you, live till I return." Lord Sc---- believed this to be a pious artifice to gain rime, but neverthelefs agreed, if he Should return by four o'clock on that day. Mr. Anfon did not return till five, and found, by the countenances of the domeftics, that the deed was done. He went into his chamber and found the corpfe of his friend leaning over the arm of a great chair, with the piftol on the ground by him, the ball of which had been difcharged into the Boof of his mouth, and paffed into his brain. "Mr.-----and Mr. ■, two young men, heirs to confiderable fortunes, Shot themfelves at the age of four or five and twenty, without their friends being able to conjeaure any caufe for thofe rafh aaions. One of them I had long known to exprefs himfelf with diffatisfaaion of the world ; at eighteen years of age he complained, that he could not en- tertain himfelf; he tried to ftudy the law at Cam- bridge, and afterwards went abroad for a year or two by my advice ; but returned diffatisfied with all things. As he had had an eruption for fome years on a part of his face, which he probably endeavoured to remove by external applications; I was induced to-afcribe his perpetual ennui to the pain or dif- agreeable fenfation of a difeafed liver. The other young gentleman Shot himfelf in his bed-room, and I was informed that there was found written on a fcrap of paper on his table. " I am impotent, and therefore not fit to live." From whence there was reafon Class III. i. 2.J OF VOLITION. 471 reafon to conclude, that this was the hallucinatio maniacalis, the delirious idea, which caufed him to deftroy himfelf. The cafe therefore belongs to mania mutabilis, and not to tsedium vitae. M. M. Some restraint in exhaufting the ufual plea- fures of the world early in life. The agreeable cares of a matrimonial life. The cultivation of fcience, as of chemiftry, natural philofophy, natural hiftory, which fupplies an inexhauftible fource of pleafurable novelty, and relieves ennui by tlie exertions it oc- cafions. In many of thefe cafes, where irkfomenefs of life has been the oftenfible caufe of filicide, there has pro- bably exifted a maniacal hallucination, a painful idea, which the patient has concealed even to his dying hour; except where the mania has evidently arifen from hereditary or acquired difeafe of the membra- nous or glandular parts of the fyftem. 12. Pulchritudinis defiderium. The loij of beaut}, either by difeafe, as by the fmall-pox, or by age, as life advances, is fometimes painfully felt by ladies, who have been much flittered on account of it. There is a curious cafe of this kind related in Le Sage's Bachelor of Salamanca, which is too nicely defcribed to be totally imaginary. In this fituation fome ladies apply to what are ter- med cofmetics under various names, which crowd the newfpapers. Of thefe the white has destroyed the health of thoufands ; a calx, or magillery, of bifmutli is fuppofed to be fold in the {hope for this purpofe ; II h 4 b::' 472 DISEASES [Class III. i. 2. but it is either, I am informed, in part or entirely white lead or ceruffa. The pernicious effeas of the external ufe of thofe faturnine applications are fpoken of in gutta rofea, Clafs II. 1. 4. 6. The real calx of bifmuth would probably have the fame ill effea. As the red paint is prepared from cochineal, which is an animal body, lefs if any injury arifes from its ufe, as it only lies on the Skin like other filth. The tan of the Skin occafioned by the fun may be removed by lemon juice evaporated by the fire to half its original quantity, or by diluted marine acid ; which cleans the cuticle, by eroding its furface, but requires much caution in the application ; the marine acid muft be diluted with water, and when put upon the hand or face, after a fecond of time, as foon as the tan dif- appears, the part muft be waShed with a wet towel and much warm water. Freckles lie too deep for this operation, nor are they in general removable by a blifter, as I once experienced. See Clafs I. 2. 2. 9. It is probable, that thofe materials which Stain Silk, or ivory, might be ufed to Stain the cuticle, or hair, permanently ; as they are all animal fubftances. -But I do not know, that any trials of this kind have been made on the ikin. I endeavoured in vain to whiten the back of my hand by marine acid oxygenated by manganefe, which fo inftantly whitens cotton. The cure therefore muft be fought from moral writers, and the cultivation of the graces of the mind, which are frequently a more valuable poffeffion than celebrated beauty. 13. Pau- Class III. i. 2.] OF VOLITION. 473 13. Paupertatis tin.or. The fear of poverty is one kind of avarice ; it is liable to affea people who have i-.'ft off a profitable and aaive bufinefs; as they are thus deprived of their ufual exertions, and are liable to obferve the daily expenditure of money, without calculating the fource from whence it flows. It is alfo liable to occur with a fudden and unexpeaed in- creafe of fortune. Mr.-----, a furgeon, about fifty years of age, who was always rather of a parfimonious difpofition, had a large houfe, with a fortune of forty thoufand pounds, left him by a diftant relation ; and in a few weeks became infane from the fear of poverty, lamenting that he fhould die in a jail or workhoufe. He had left off a laborious country bufinefs, and the daily perception of profit in his books; he alfo now faw greater expences going forwards in his new houfe, than he had been accuftomed to obferve, and did not fo diftinaiy fee the fource ©f fupply; which feems to have occafioned the maniacal hallucination.—This idea of approaching poverty is a very frequent and'very painful difeafe, fo as to have induced many to become filicides, who were in good circumftances ; more per- haps than any other maniacal hallucination, except the fear of hell. The covetoufnefs of age is more liable to affea fingle men, than thofe who have families; though an accumulation of wealth would feem to be more defira- ble to the latter. But an old man in the former Situ- ation, has no perfonal conneaions to induce him to open his purfe; and having loft the friends of hi* youth, 474 DISEASES [Class III. i. 2. youth, and not eafily acquiring new ones, feels him- felf alone in the world ; feels himfelf unproteaed, as his ftrength declines, and is thus led to depend for affiftance on money, and on that account wiflies to accumulate it. Whereas the father of a family has not only thofe conneaions, which demand the fre- quent expenditure of money, but feels a confolation in the friendship of his children, when age may ren- der their good offices neceffary to him. M. M. I have been well informed of a medical per- fon in good circumftances in London, who always carries an account of his affairs, as debtor and credi- tor, in his pocket-book ; and looks over it frequently in a day, when this difeafe returns upon him ; and thus, by counteraaing the maniacal hallucination, wifely prevents the increafe of his infanity. Another medical perfon, in London, is faid to have cured him- felf of this difeafe by ftudying mathematics with great attention; which exertions of the mind relieved the pain of the maniacal hallucination. Many moral writers have ftigmatifed this infanity; the covetous, they fay, commit crimes and mortify themfelves without hopes of reward; and thus be- come miferable both in this world and the next. Thus Juvenal : Cum furor haud dubius, cum fit manifefta phrenitis, Ut locuples moriaris, egenti vivere fato ! The covetous man thought he gave good advice to the fpendthrift, when he faid, " Live like me," who well anfwered him, " Like Class III. i. 2.] OF VOLITION. 475 -----------" Like you, Sir John I " That I can do, when all I have U gone !" PoPE. 14. Lethi timor. The fear of death perpetually employs the thoughts of thefe patients ; hence they are devifing new medicines, and applying to phy- sicians and quacks without number. It is confounded with hypochondriafis, Clafs I. 2. 3. 9. in popular con- verfation, but is in reality an infanity. A young gentleman, whom I advifed to go abroad as a cure for this difeafe, affured me, that during the three years he was in Italy and France he never paffed a quarter of an hour without fearing he fliould die. But has now for above twenty years experienced the contrary. The fufferers under this malady are generally at once difcoverable by their telling you, amidft an un- conneaed defcription of their complaints, that they are nevertheless not afraid of dying. They are alfo eafily led to complain of pains in almoft any part of the body, and are thus foon difcovered. M. M. As the maniacal hallucination has generally arifen in early infancy from fome dreadful account of the Struggles and pain of*dying, I have fometimes ob- ferved, that thefe patients have received great con- folation from the inftances 1 have related to them of people dying without pain. Some of thefe, which I think curious, I fliall concifely relate, as a part of the method of cure, 47S DISEASES [Class III. i. 2. Mr.----, an elderly gentleman, had fent for me one whole day before I could attend him; on my ar- rival he faid he was glad to fee me, but that he was now quite well, except that he was weak, but had had a pain in his bowels the day before. He then lay in bed with his legs cold up to the knees, his hands and arms cold, and his pulfe fcarcely difccrnible, and died in about fix hours. Mr.----, another gen- tleman about fixty, lay in the aa of dying, with dif- ficult refpiration like groaning, but in a kind of ftupor or coma vigil, and every ten or twelve minutes, while I fat by him> lie waked, looked up, and faid, " who is it groans fo, I am fore there is fomebody dying in the room," and then funk again into a kind of fleep. From thefe two cafes there appeared to be no pain in the aa of dying, which may afford confolation to all, but particularly to thofe who are affliaed with the fear of death. 15. Orel timor. The fear of hell. Many theatric preachers among the Methodifts fuccefsfully infpire this terror, and live comfortably upon the folly of their hearers. In this kind of madnefs the poor pa- tients frequently commit filicide; although they be- lieve they run headlong into the hell, which they dread ! Such is the power of oratory, and fuch the debility of the human understanding! Thofe, who fuffer under this infanity, are gene- rally the moft innocent and harmlefs people ; who are then iiabie to accufe themfelves of the greateft ima- ginary Class III. i. 2.] OF VOLITION. 477 ginary crimes, and have fo mrch intelfeaual cowardice, that they dare not reafon about thofe things, which they are direaed by their priefts to believe, however contradiaory to human a prehenfbn, or derogatory to the great Creator of all things. The maniacal hallucination at length becomes fo painful, that the poor infane flies from life to become free from it. M. M. Where the intelfeaual .cowardice is great, the voice of reafon is ineSfeaual ; but that of ridicule may fave many from thofe mad-making doaors ; though it is too weak to cure thofe, who are already hallucinated. Foot's Farces are recommended for this purpofe. 16. Satyriafis. An ungovernable defire of venereal indulgence. The remote caufe is probably the ftimulus of the femen ; whence the phallus becomes diftended with blood by the arterial propulsion of it being more Strongly excited than the correspondent venous abforp- tion. At the fame time a new fenfe is produced in the other termination of the urethra ; which, like itching, requires fome exterior friaion to facilitate the removal of the caufe of the maniacal aaions, which may probably be increafed in thofe cafes by fome affo- ciated hallucinations of ideas. It differs from priapif- mus chronicus in the defire of its appropriated objea, which is not experienced in the latter, Clafs I. 1.4. 6. and from the priapifmus amatorius, Clafs II. 1. 7. 9. in the maniacal aaions in confequence of defire. The furor uterinus, or nymphomania, is a fimilar difeafe. M. M. Vene- 4/5 DISEASES [Class III. i. i. M. M. Venefeaion. Cathartics. Torpentia. Mar- riage. 17. Ira. Auger is caufed by the pain of offended pride. Wre are not angry at breaking a bone, but become quite infane from the fmalleft ilroke of a whip from an inferior. Ira furor brevis. Anger Is not only itfelf a temporary madnefs, but is a frequent at- tendant on other infanities, and as, whenever it ap- pears, it diftinguiflies infanity from delirium, it is ge- nerally a good fign in fevers with debility. An injury voluntarily infliaed on us by others ex- cites our exertions of felf-defence or of revenge againft the perpetrator of it; but anger does not fucceed in any great degree unlets our pride is offended ; this idea is the maniacal hallucination, the pain of which fometimes produces fuch violent and general exertions of our mufcles and ideas, as to*difappoint the revenge we meditate, and vainly to exhauft our fenforial power. Hence angry people, if not further excited by difagreeable language, are liable in an hour or two to become humble, and forry for their violence, and willing to make greater conceffions than required. M. M. Be filent, when you feel yourfelf angry. Never ufe loud oaths, violent upbraidings, or ftrong expreffions of countenance, or gesticulations of the arms, or clenched fills ; as thefe by their former affo- ciations with anger will contribute to increafe it. I have been told of a fergeant or corporal, who began moderately to cane his fjlilers, when they were awk- ward Class III. i. *.] OF VOLITION. 4/f ward in their exercife, but being addiaed to fwearing and coarfe language, he ufed foon to enrage himfelf by his own expreffions of anger, till toward the end he was liable to beat the delinquents unmercifully. 18. Rabies. Rage, A defire of biting others, moft frequently attendant on canine madnefs. Ani- mals in great pain, as in the colica faturnina, are faid to bite the ground they lie upon, and even their own flefli. I have feen patients bite the attendants, and even their own arms, in the epilepfia dolorifica. It feems to be an exertion to relieve pain, as ex- plained in Sea. XXXIV. 1. 3. The dread of water in hydrophobia is occafioned by the repeated painful attempts to fwallow it, and is therefore not an effen- tial or original part of the difeafe called canine mad- nefs. See Clafs III. 1. 1. 15. There is a mania reported to exift in fome parts of the eaft, in which a man is faid to run a muck; and thefe furious maniacs are believed to have in- duced their calamity by unlucky gaming, and after- wards by taking large quantities of opium ; whence the pain of defpair is joined with the energy of drunkennefs; they are then faid to fully forth into the moft populous Streets, and to wound and flay all they meet, till they receive their own death, which they defire to procure without the greater guilt, as they fuppofe of fuicide. M. M. When there appears a tendency to bite in tlie painful epilepfy, the end of a rolled-up towel, or 4-^0 DISEASES [Class III. i. 2. or a wedge of foft wood, fhould be put into the mouth of the patient. As a bullet is faid fometimes to be given to a foldier, who is to be feverely flog- ged, that he may by biting it better bear his pu- nifliment. 19. Ciita. A defire to fwallow indigestible fob- fiances. I once faw a young lady, about ten years of age, who filled her ftomach with the earth out of a flower-pot, and vomited it up with fmall-ftones, bits of wood, and wings of infeas amongft it. She had the bombycinous complexion, and looked like a chlorotic patient, though fo young; this generally proceeds from an acid in the Stomach. M. M. A vomit. Magnefia alba. Armenian bole. Rhubarb. Bark. Steel. A blifter. See Clafs I. 2. 4. 5. 20. Cacofitia. Averfion to food. This may arife, without difeafe of the ftomach, from conneaing nau- fecuj ideas to our ufual food, as by calling a ham a hog's a-----. This madnefs is much inculcated by the Stoic philofophy. See Antoninus' Meditations. See two cafes of patients who refuted to take nourish- ment. Clafs III. 1. 2. 1. Aversions to peculiar kinds of food are thus formed early in life by affociation of fome maniacal hallucina- tion with them. I remember a child, who on tatting the griftle of fturgeon, alked what griftle was ? And feeing told ir was like the divifion of a man's nofe, re-- 2 reived Class til. i. 2.] OF VOLITION. 4«h ceived an ideal hallucination ; and for twenty years afterwards could not be perfuaded to tafte fturgeon. The great fear or averfioil, which fome people ex- perience at the fight of fpiders, toads, crickets, and the like, have generally had a fimilar origin. M. M. Affociate agreeable ideas with thofe which difguft; as call a fpider ingenious, a frog clean and innocent ; and reprefs all expreffions of difguft by the countenance, as fuch expreffions contribute to pre- ferve, or even to increafe, the energy of the ideas affociated with them; as mentioned above in Species 17, Ira. 21. Syphilis imaginaria. The fear that they are infeaed with the venereal difeafe, when they have only deferved it, is a very common infanity amongft modeft young men; and is not to be cured without applying artfully to the mind ; a little mercury muft be given, and hopes of a cure added weekly and gra- dually by interview or correfpondence for fix or eight weeks. Many of thefe patients have been repeatedly falivated without curing the mind ! 22. Pfora imaginaria. I have twice feen an ima- ginary itch, and twice an imaginary diabsetes, where there was not the leaft veftige of either of thofe dif- eafes, and once an imaginary deafnefs, where the pa- tient heard perfeaiy well. In all thefe cafes the hal- lucinated idea is fo powerfully excited, that it is not 1:0 be changed fuddenly by ocular fenfation, or reafon. Ii Yet 4*2 DISEASES [Class III. 1.2. Yet great perfeverance in the frequently prefenting contrary ideas will fometimes flowly remove this hal- lucination, or in a great length of time oblivion, or forgetfulnefs, performs a cure, by other means in vain attempted, 23. Tabes imaginaria. This imaginary difeafe, or hallucination, is caufed by the fuppofed too great frequency of parting with the femen, and had long impofed upon the phyfician as well as the patient, till Mr. John Hunter firft endeavoured to Shew, that in general the morbid effeas of this pollution was'in the imagination ; and that thofe were only liable to thofe effeas in general, who had been terrified by 1 the villanous books, which pretend to prevent or to cure it, but which were purpofely written to vend fome quack medicine. Moft of thofe unhappy patients, whom I have feen, had evidently great imprelfion of fear and felf-condemnation on their minds, and might be led to make contradiaory complaints in almoft any part of the body, and if their confeffions could be depended on, had not ufed this pollution to any great excefs. M. M. 1. Affure them if the lofs of the femen hap- pens but twice a week, it will not injure them. 2. Marry them. The laft is a certain cure; whether the difeafe be real or imaginary. Cold partial bath, and aftringent medicines frequently taken, only reeal the mind to the difeafe, or to the delinquency; and thence increafe the imaginary effeas and the real caufe, if Class III. i. 2.] OF VOLITION. 4*3 if fuch exifts. Mr.-----deftroyed himfelf to get free from the pain of fear of the fuppofed ill confequences of felf-pollution, without any other apparent difeafe; whofe parents I had in vain advifed to marry him, if poffible. 24. Sympathia alicna. Pity. Our fympathy with the pleafures and pains of others diftinguiflies men from other animals ; and is probably the foundation of what is termed our moral fenfe ; and the fource of all our virtues. See Sea. XXII. 3. 3. When our fympathy with thofe miferies of mankind, which we cannot alleviate, rifes to excefs, the mind becomes its own tormenter ; and we add to the aggregate fum of human mifery, which we ought to labour to diminish ; as in the following eloquent lamentation from Aken- fide's Pleafures of Imagination, Book II. 1. 200. -----------------------Dark, As midnight ftorms, the feene of human things Appear'd before me ; defer ts, burning finds, Where the parch'd adder dies; the frozen fouth ; And defolation blading all the weft With rapine and with murder. Tyrant power Here fits enthroned in blood*; the baleful charms Of fuperftition there infect the ikies, And turn the fun to horror. Gracious Heaven { What is the life of man ? Or cannot thefe, Not thefe portents thy awful will fuffice? That, propagated thus beyond their fcope, They rife to a.!t their cruelties anew In my afflicT^d bofom, thus decreed The univerfal fenfitive of pain, The wretched heir of evils not its own ! Ii 2 A pee 4^4 DISEASES [Cuss III. i. *. A poet of antiquity, whofe name I do not recol- fea, is faid to have written a book defcribing the miferies of the world, and to have deftroyed himfelf at the conclufion of his tafk. This fympathy, with all fenfitive beings, has been carried fo far by fome individuals, and even by whole tribes, as the Gen- reos, as not only to reftrain them from killing animals for their fupport, but even to induce them to permit infeas to prey upon their bodies. Such is however the condition of mortality, that the firft law of nature is, " Eat or be eaten." We cannot long exift with- out the deftruaion of other animal or vegetable beings, either in their mature or their embryon ftate. Unlets the fruits, which furround the feeds of fome vegetables, or the honey Stolen from them by the bee, may be faid to_.be an exception to this affertion. See Botanic Garden, P. I. Cant. 1.1. 278. Note. Hence, from the neceffity of our nature, we may be fuppofed to have a right to kill thofe creatures, which we want to eat, or which want to eat us. But to deftroy even infeas vmtonly Shews an unrefieaing mind or a de- prived heart. Neverthelefs mankind may be well divided into the feliiih and the focial; that is, into thofe whole plea- fures arife from gratifying their appetites, and thofe whofe pleafures arife from their Sympathizing with or hers. And according to the prevalence of thefe oppo- sing propensities we value or diflike the poffefforof them. In conduaing the education of young people, it h a nice matter to infpire them with fo much benevolent fympathy, Class, III. i. 2.] OF VOLITION. 4Sj fympathy, or compaffion, as may render them good and amiable ; and yet not fo much as to make them unhappy at the fight of incurable diftrefs. We fliould endeavour to make them alive to Sympathize with all remediable evils, and at the fame time to arm them with fortitude to bear the fight of fuch irremediable evils, as the accidents of life muft frequently prefent before their eyes. About this I have treated more at large in a plan for the condua of a boarding fchool for ladies, which I intend to publifli in the courfe of the next year. 25. Educatio heroica. From the kinds and degrees of infanities already enumerated, the reader will pro- bably recolfea many more from his own obfervation ; he will perceive that all extraordinary exertions of vo- luntary aaion in confequence of fome falfe idea or hal- lucination, which Strongly affeas us, may philosophi- cally, though not popularly, be termedv an infanity ; he will then be liable to divide thefe voluntary exer- tions into difagreeable, pernicious, deteftable, or into meritorious, defeaable, and even amiable, infanities. And will laftly be induced to conceive, that a good education confifts in the art of producing fuch happy hallucinations of ideas, as may be followed by fuch voluntary exertions, as may be termed meritorious cl- aimable infanities. The old man of the mountain in Syria, who ge- verned a fmall nation of people called" Afiaftine.', h recorded thus to have educated thofe of his nrinv who 486 DISEASES [Class III. i. 2. were defigned to affaffinate the princes with whom he was at war. A young man of natural aaivity was chofen for the purpofe, and thrown into a deep fleep by opium mixed with his food ; he was then carried into a garden made to reprefent the paradife of Maho- met, with flowers of great beauty and fragrance, fruits of delicious flavor, and beautiful houries beckon- ing him into the fhades. After a while, on being a fecond time ftupified with opium, the young enthufiaft was reconveyed to his apartment; and on the next day was affured by a prieft, that he was defigned for fome great exploit, and that by obeying the com- mands of their prince, immortal happinefs awaited him. Hence it is eafy to colfea how the firft ImpreSfions made on us by accidental circumftances in our infancy continue through life to bias our affeaions, or miflead our judgments. One of my acquaintance can trace the origin of his own energies of aaion from fome fuch re- mote fources; which juftifies the obfervation of M. Rouffeau, that the feeds of future virtues or vices are oftener fown by the mother, than the tutor. END "OF VOL! 1. OF PAR'fit," \ ★ ★ ARMY * * MEDICAL LIBRARY Cleveland Branch Mod. Hist Jk70 v. I