V**\tV: /*"; "& m n %% '-?%% •■* '.^-'i :'^ U. *£ PSt^w"^ :£ •;*---i*. ARMED FORCES MEDICAL LIBRARY Washington, D. C. »GV ^ c 5 ®fo §nmM pfomjj. PRESENTED TO \\t |«rkebg ^ibhrftg §4**1, S IN ACCORDANCE WITH THE WISHES OP THE Eev. HENEY W. DUCAOHET, M.D., D.D., Rector of St. Stephens Church, Philadelphia, U^^ BY HIS RELICT, ANN D. DUCACHET. -o- "\Sf &**r JV.^tte* .V zfno . OBSERVATIONS ON THE EPIDEMICAL DISEASES OF MINORCA. FROM THE YEAR 1744 TO 1749. TO WHICH IS PREFIXED A short Account of the Climate, Productions, Inhabitants, and Endemial Distempers of Minorca. BY GEORGE CLEGHORN, M. D. Professor of Anatomy in the University of Dublin. WITH NOTES, &c. BY BENJAMIN RUSH, M. D. Professor of the Institutes and Practice of Medicine in the University of Pennsylvania. SECOND AMERICAN EDITION. PHILADELPHIA: PRINTED FOR F. NICHOLS. William Fry, Printer. 1812. District of Pennsylvania, to wit: »*♦****** gE IT remembered> That on the seventeenth J L. S. * day of October, in the thirty-seventh )'ear of the »***»•**£ Independence of the United States of America, A. D. 1812, Francis Nichols, of the said district, hath deposited in this office, the title of a book, the right whereof he claims as proprietor, in the words following to wit: " Observations on the Epidemical Diseases of Minorca. " From the year 1744 to 1749. To which is prefixed a " SJiort Account of the Climate, Productions, Inhabi- " tants, andEndemial Distempers of Minorca By George " Cleghorne, M D. Professor of Anatomy in the Univer- sity of Dublin. With Notes, &c. By Benjamin Rush, " M. D. Professor' of the Institutes and Practice of " Medicine in the University of Pennsylvania. Second " American Edition." In conformity to the act of the Congress of the United States, intitled, " An act for the encouragement of learning, by securing the copies of Maps, Charts, and Books, to the authors and proprietors of such copies during the times therein mention- ed."—And also to the act, entitled, " An Act supplementary to an Act, intituled, " An Act for the encouragement of learn- ing, by securing the copies of Maps, Charts, and Books, to the authors and proprietors of such copies during the times therein mentioned," and extending the benefits thereof to the arts of designing, engraving, and etching historical and other prints." D. CALDWELL, Clerk of the District of Pennsylvania. TO THE STUDENTS OF MEDICINE IN THE UNIVERSITY OF PENNSYLVANIA. GENTLEMEN, 1 HE following work contains a greater mass of practical knowledge in a small compass, than any- book perhaps of the same kind in medicine. It has passed through many editions, and it now occupies a place in the libraries of most of the physicians in the British empire. Its merit consists chiefly in the number and importance of its facts, which afford the surest passport of a medical book to present and future generations. The notes which I have added to this first American edition of this valuable work, are intended to point out a few of its errors, but chiefly to impress those remarks, upon your minds, which accord with the diseases and mode of prac- tice that are common in the United States. The notes to which I allude, are distinguished from those of the author, by the references being made by means of the letters of the alphabet. Permit me to recommend to your imitation the same practice in improving the science of medicine, which has been pursued by the author of this work. It consists, as you will perceive, in delivering dis- 9 iv DEDICATION. eases from the insulated place they held in systems of nosology, and connecting them with climate, sea- son, aliments, drinks, dress, and national manners. To enable you to imitate our author with success, it will be necessary to record facts as they occur. " Studium sine calamo, somnium," said the Latin poet. The same thing may be said of the most ex- tensive practice, where notes are not made of dis- eases. A correct knowledge of them, however strongly impressed upon the mind at the time they are seen, will pass out of the memory like a dream in the course of a few years. By recording the facts which relate to them, the extremes of youth and age may be made to meet in a middle point, or in other words, the benefits of long experience may be anti- cipated in early life. The book now in your hands is a proof of the truth of this remark. It was com- posed and published before the author had attained the thirty-fourth year of his age. In composing the notes which I have added to this work I have taken it for granted that you are ac- quainted with the principles of medicine which I have taught in the university of Pennsylvania, and of course I have omitted an explanation of them in the occasional references I have made to them. I shall conclude this dedication by subjoining the following account of the life of our author extracted from Dr. Benjamin Hutchinson's Biographia Medi- ca, from which )tou will discover some other of the means, beside those that have been mentioned, by which he acquired his knowledge and reputation in his profession. " Dr. George Cleghorn was born of reputable pa- DEDICATION. V rents at Granton, in the parish of Crammond, near Edinburgh, on the 18th of December, 1716. His fa- ther died in 1719, and left a widow and five chil- dren. George, who was the youngest son, received the rudiments of his education in the grammar school of Crammond, and in the year 1728, was sent to Edinburgh, to be further instructed in the Latin, Greek, and French; where, to a singular profkiency in these languages, he added a considerable stock of mathematical knowledge. " In the beginning of the year 1731 he resolved to study physic and surgery, and had the happiness of being placed under the tuition of the late Dr. Alex- ander Monro, a name that will be revered in that university, as long as science shall be cherished and cultivated. This great professor was esteemed by all, but especially by those who were more imme- diately under his direction. It was the lot of young Cleghorn to live under his roof; and, in one of his letters, his pupil appeared to dwell with peculiar pleasure upon this circumstance, observing that4 his amiable manners, and unremitting activity in pro- moting the public welfare, endeared him to all his acquaintance, but more particularly to those who lived under his roof, and had daily opportunities of admiring the sweetness of his conversation, and the invariable benignity of his disposition.' For five vears he continued to profit by the instruction and example of his excellent master, visiting patients in company with him, and assisting at the dissections in the anatomical theatre; at the same time he at- tended in their turn the lectures in botany, materia medica, chemistry, and the theory and practice of hie- a 2 VI DEDICATION. dicine; and by extraordinary diligence he attracted the notice of all his preceptors. " On Dr. Fothergill's arrival from England at this university, in the year 1733, Dr. Cleghorn was introduced to his acquaintance, and soon became his inseparable companion. These pupils then studied together the different branches of science under the same masters, with equal ardour and success; they frequently met to compare the notes they had col- lected from the professors, and to communicate their respective observations. Their moments of relaxa- tion, if that time can be called relaxation, which is devoted to social studies, were spent in a select so- ciety of fellow students, of which Fothergill, Rus- sel, and Cuming, were associates; a society since incorporated under the name of the Royal Medical Society of Edinburgh. " Early in the year 1736, when young Cleghorn had scarcely entered into his twentieth vear, so great had been his progress, and so high a character had he acquired, that, upon the recommendation of Dr. St. Clair, he was appointed surgeon in the 22d re- giment of foot, then stationed in Minorca, under the command of general St. Clair. During a residence of thirteen years in that island, whatever time could be spared from attending the duties of his station, he employed, either in investigating the nature of epidemic diseases, or in gratifying the early passion he had imbibed for anatomy, frequently dissecting human bodies, and those of apes, which he had pro- cured froni Barbary, and comparing their structure with the descriptions of Galen and Vesalius. In these pursuits he was much assisted by his corre- DEDICATION. vn spondent Dr. Fothergill, who, he acknowledges, was indefatigable in searching the London shops for such books as he wanted. " In 1749 he left Minorca, and went to Ireland with the 22d regiment, and in the autumn of 1750 he went to London, and, during the publication of ' The Diseases of Minorca,' attended Mr. Hunter's anatomical lectures. In the publication of his book he was materially assisted by Dr. Fothergill. Of this work the following eulogium has been pronounced by a competent judge: ' It forms a just model for the imitation of future medical writers; it not only exhibits an accurate state of the air, but a minute detail of the vegetable productions of the island, and concludes with medical observations important in every point of view, and in some instances, either new, or applied in a manner which preceding practitioners had not admitted.' It is a practice for which we stand indebted to Dr. Cleghorn, to recommend acescent vegetables in low, remittent, and putrid fevers, and the early and copious exhibi- tion of bark, which had been interdicted, from mistaken facts, deduced from false theories. " In 1751 the doctor settled in Dublin; and, in imitation of Monro and Hunter, began to give an- nual courses of anatomy. A few years after his re- sidence in Dublin he was admitted into the univer- sity as lecturer in anatomy. In the year 1784 the college of physicians of that city elected him an honorary member; after which, from lecturer in anatomy, he was made professor, and had likewise the honour of being one of the original members of the Irish academy for promoting arts and sciences, which is now established by royal authority. In Vlll DEDICATION. 1777, when the royal medical society was established at Paris, he was nominated a fellow ofit. " About 1774, on the death oi his only brother in Scotland, he sent for his surviving family, consisting of the widow and nine children, and settled them in Dublin under his own eye, that he might have it more in his power to afford them that protection and assistance of which they might stand in need. His eldest nephew, William, he educated in the medical profession; but after giving him the best education which Europe could afford, and getting him joined with himself in the lectureship, the doctor's pleasing hopes were unfortunately frustrated by the young gentleman's death, which happened about the year 1784. " Dr. Cleghorn, with an acquired independence, devoted his moments of leisure to farming and hor- ticulture. But his attention to these employments did not diminish his care of his relations, who, from a grateful and affectionate regard, looked up to him as a parent: the duties of which station he so ten- derly supplied, as to induce Dr. Lettsom, from whose memoirs this account is taken, to apply to him the words of Horace, ' Notus in fratres animi paterni.' Dr. Cleghorn died in December 1789." With cordial salutations, I am, gentlemen, verv respectfully your sincere friend, BENJAMIN RUSH. September 1809 TO THE SOCIETY OF SURGEONS OF HIS MAJESTY'S ROYAL NAVY. GENTLEMEN, jA.S many of you must be sensible, how little the best information we can acquire in this temperate climate, qualifies us for treating the diseases which are frequent in warmer latitudes, with the desired success, I take the liberty to address the following sheets to your society. They contain, it is true, an account of the diseases only of a small, remote part of the British dominions; but of a part in which numbers of his majesty's sub- jects, beside the natives and those employed in the protection of the place, are often brought together, both in time of peace and war: and as the qualities of the air, and the course of the seasons in Minorca correspond nearly with those in several other parts of the world, to which our fleets frequently repair, it is probable that the diseases may likewise be similar. Would all who practise physic in our factories and colonies abroad embrace the opportunity which their situation affords, to make proper observations on the sick, and communicate them to the public, we should X DEDICATION. soon have a more exact and ample history of dis- eases, than we are yet possessed of; and future prac- titioners would be enabled to shun the dangers into which many have fallen, and to conduct those com- mitted to their care through the disorders to which they are exposed, with satisfaction and honour to themselves, and no small benefit to their country. It is therefore with great pleasure that I see this is particularly recommended, in the plan for publishing medical observations, which you have lately esta- blished, and will, it is hoped, prosecute with the vigour which so useful an institution deserves. For my own part, I must confess, I had not been long in Minorca ere I had great reason to wish that some of the practitioners who had been there before me, and who must have seen how widely the predo- minant distempers in this island differ from those in England, had been at the pains to furnish their suc- cessors with some hints, some observations, by which the fatal consequences frequently attending these diseases, might have been timely foreseen, or hap- pily prevented. Being therefore fully convinced, that some re- marks of this nature might be useful to those who should afterwards practise in this island, I determin- ed to observe and record, with the utmost care and impartiality, whatever should appear conducive to a thorough knowledge of its diseases and their cure; imagining that, next to the immediate care of the sick, this would be the most essential service, which one in my station could render to the public. With this view, in the year 1743, I began to keep a diary of the weather, to remark the course of the DEDICATION. 'xi seasons, to describe the diseases which they pro- duced, and that commonly in the chambers of the sick: which diary I continued, with no small labour and assiduity, in the midst of an extensive practice, both among the English and Natives, till the year 1749, when the removal of the regiment, in which I have the honour to serve, obliged me to leave the island, and furnished me with leisure for revising my observations, and collecting, from a vast multi- tude of cases, such general remarks as appeared worthy to be communicated to the public. You will observe that amongst the epidemics of Minorca, tertian fevers make the most considerable part. The diversity of their types, the violence of their symptoms, their fallacious intermissions, their sudden, and too frequently pernicious events, ren- dered it necessary to give an explicit account of themj and the more so, as they seldom appear in this man- ner in the northern parts of Europe; though in Greece, in Italy, and the adjacent countries, it is evident from the remains of antiquity,* and the writings of the most judicious moderns,f that they ever have been, and still are, very frequent, and that with a surprising constancy and uniformity of symptoms; though to one who never had an oppor- tunity of observing them in all shapes, nor seen them amply described, they have the appearance of great irregularity and confusion. * Hippocrat. Aphor. § iii. No. 21, and De Morb. Vulg. Lib. vit. Asclepiad. apud Cxi. Aurel. de Morb. Acut. Lib. ii. Cap. x. Galen de Morb. Temp, sub finem. t River. Lib. xvii. § iii Cap. i. Lancis. Epid. Torti Thera- peuu Special. Bianch. Hist. Hepat. p. 3, 8cc. Xll DEDICATION. And it is more than probable, from the accounts of several physicians* and travellers, that epidemi- cal tertians are not wholly confined to the coasts and islands of the Mediterranean; but that they are equally frequent and destructive in many other parts of the globe, and perhaps may be deemed the anni- versary autumnal distempers of most hot countries in the world. t A tertian, it is true, when once discovered, may for the most part be readily cured, as we have so safe and efficacious a remedy as the bark in our hands. But in warm climates, such is the rapid pro- gress of this distemper, that it is requisite we should know it in the beginning, that no opportunity may be lost of giving the remedy in a sufficient quantity to avert those dangers into which the sick are other- wise very soon precipitated: yet the variableness of its aspect, and its frequently personating other acute diseases, render this often difficult to the most ex- perienced; and much more so to those who have seldom or never seen such tertians, as they are only now and then to be met with in England. These considerations induce me to believe, that the account of them contained in the following pages, will neither be unacceptable nor useless to many of your society; and particularly to those, who, by their station in his majesty's service, are often obliged to take care of numbers of their fellow subjects, in climates exposed to such disorders; whilst at the same time their quick transition from one place to * Spigel. de Semitertian. Lib. iii. Cap. i. Tennent on the Diseases of Virginia, p. 12. Warren on the Fever of Barbadoes, p. 70. DEDICATION. xiii another, prevents their acquiring a competent know- ledge of the various epidemics from their own ob- servation. To you therefore, gentlemen, I address these re- marks with the utmost deference and esteem, being in hopes, that the motives which prevailed with me to offer them to you and the public, will sufficiently plead my apology to both, for any imperfections which may appear in this performance, with regard to method or expression. I am, Your most humble servant, G. CLEGHORN. b CONTENTS. INTRODUCTION. The Air in Minorca............Page 1 The Seasons of the Year............ 2 Heat and Cold . ;............. 2 Winds......;........... 3 Rain, and other Meteors............ 4 The Soil, and its Productions.....*. . . . . 6 Corn.................... 7 Wine.................... 7 Pulse..................... 8 Roots, Sallads, and Pot-herbs.......... 9 Fruits and Trees cultivated ..........'. 11 indigenous..........21 Minerals.................26 Fish . •..................27 Cattle .................. Domestic Fowl...............ZX Wild Fowl.................32 Water Fowl................32 Birds of Passage..............32 Eatable Snails...............34 The natural Temper of the Minorquines ....... 34 Their Diet................35 Their Festivals and Public Diversions.......37 Their ancient Usages.............39 Endemia) Diseases .............42 Obstructions of the Abdominal Viscera .... 42 Hemorrhoids . . . ..........44 Ulcers of the Legs ...........44 Ruptures...............45 Sore Eyes.............. 45 Nephritic Pains......'......45 Convulsion of the Jaw in Children......46 Accidents from endemial Causes......47 Their Notions of Witchcraft and evil Spirits.....48 xvi CONTENTS. CHAPTER I. The Weather described from the Year 1744 to 1749 Page 49 A Thermometries Table...........73 CHAPTER If. A short Account of the epidemical Diseases from 1744 to 1749.........\........75 CHAPTER III. Tertian Fevers, why so called..........85 The Diversity of Tertians occasioned by the different Types of their Periods, viz. Simple Tertians, true and spurious......88 Double Tertians............88 True, Spurious, and Subin^rant Double Tertians . 89 Triple Tertians.............89 Semitertians.....nar, C 2 30 INTRODUCTION. they make but little butter, and this by a very sin- gular process. They boil the whey, which is pressed from the curd in making cheese, and skim off the part which rises to the top; when they have collect- ed a proper quantity of this, they work it a considera- ble time with their bare feet or arms, the only method Pisces Pelagii. Peix de alt al mur. (22) Gurnardus griseus, Uliora, Baluerna. (23) Draco sive Araneus Plinii, Arana. (24) An Ophidion Rond.? an Acus lumbriciformis Willough.? Drago, Saltan cono. (25) Uranoscopus, Callyonimus, Rata- (26) An Perca marina Rond.? Serran imperial. (27) An Stromateus Rond? Llampuga. (28) Pompilus, Pampul. Pisces gregales autumnales. (1) Acus vulgaris oppian. Aguia. (2) Sardinia Rond. Sardina. (3) Thrissa Rond. Alatx. Pisces gregales hyemales. 1) Pelamys Bellon. Amia Rond. Bonitol. Pisces gregales vernales. (1) An Thynni species? Sirvia, Sirviola (2) Sphyrxna, sive Sudis Aldr. Espet. Pisces gregales JEstivi. vl) Scomber, Veirat, Cavallar. (2) Trachurus Aid. Saurell. (3) Maenje duplex species, Mora & Xucla. (4) Smaris, Gerretts. (5) Boops Rond. primus, Voga. < (6) Encrasicholus Aldr. Anxove, Aledroc. Note. In the above catalogue offish it is to be observed that IVilloughby's names are commonly made use of; and such as are marked with an asterisk are seldom or never brought to table. INTRODUCTION. 31 of churning with which they are acquainted; then by the addition of cold water the butter which floats upon the surface is separated; and after being washed is boiled till the watery particles are evaporated. By this process it acquires, when cold, the taste and consis- tency of a thick, sweet, oil. Beef and mutton, though commonly lean, are eata- ble throughout the year: but in the spring, while the grass is tender, the latter is in its greatest perfection; and the former in summer, when the cattle feed on the stubble and leaves of the evergreens. The goats are fattest in autumn, and are slaugh- tered from September to January, chiefly for the use of the common people. But of all the kinds of meat none is here in so great plenty and perfection as pork; nor is any other so much esteemed by the natives. It is in season from September to Lent. Bacon is to be had at all times; and, being fried or boiled, is commonly eat with bread for breakfast. They enrich their broth with hog's lard; and from the same animal they make a great variety of puddings, particularly sau- sages (sobreassados), scarce inferior to^those from Bologna. They have likewise plenty of rabbits; as also hedgehogs, and land turtles, which are sometimes eat by the poor. Their domestic fowls are turkeys (1), geese (2), ducks (3), cocks and hens (4), in great numbers. (1) Gallo pavo sive meleagris, Galls de India. (2) Anser domesticus, Ojas. (3) Anas domestica, Anades- f4) Gallus gallinac. & Gallina, Galls Cf Gallinas. 32 INTRODUCTION. In the woods and fields (besides various kinds ot owls and birds of prey, which I pass over, as they never make a part of diet) we have ring doves (l), red legged partridges (2), stone curlews (3), quails (4), blackbirds (5), solitary sparrows (6), nightin- gales (7), gold-finches (8), and an infinite number of other small birds. Wild ducks of different kinds (9), wigeons (10), teal (11), coots (12), and several sorts of water hens (13), are common about the ponds and marshes; kings-fishers (14) are frequent about the shore; and flocks of rock-pigeons (15) breed in the caves and hollows, formed by the dashing of the waves round the coasts. Beside all these, swifts (16), swallows (17), sand martins (18), turtles (19), bee eaters (20), hoo- (1) Palumbus torquatus Aldr. Tudons. (2) Perdix ruffa, Perdius. (3) Oedicnemus Bellon. Charadrius Gesner. Sabellins. (4) Coturnix, Gualleras. (5) Merula vulgaris, Torts. (6) Passer solitarius, Melleres. (7) Luscinia seu Philomela, Rossinols. (8) Carduelis, Carderneras. (9) Anas fera, varia specie, Anades rosas de coll blau, sayar- -n-i. soteras. (10) Penelope. (11) Querquedula, Anadons. (12) Fulica, Fotges. (13) Gallinula varia specie, Polio's de Riu Gallets de Riu ti- -'."•as. (14) Ispida, an Veterum Alcyon? (15) Columba rupicola, Coloms. (16) Hirundo Apus, Vinjolas. (17) Hirundo domestica, Uranellas. (18) Hirundo riparia, Culs blanchs. (19) Turtur, Tortora. C20) Merops sive Apiaster, AbeyrcU INTRODUCTION. 33 po's (1), and sky larks (2), arrive here in the spring, and, after bringing forth their young, leave the island in autumn. Woodcocks (3), snipes (4), a small sort of pi- geon (5), green and gray plovers (6), redwings (7), fieldfares (8), oxeyes (9), chaffinches (10), star- lings (11), foreign quails (12), and daker-hens (13), make their appearance about the end of October, and remain during the winter. Cranes (14), wild geese (15), and curlews (16), sometimes stop here, as if it were to recruit themselves for a further flight; and now and then we meet with a flamenco (17). It is observed that the flesh of such fowls as feed on land frequently tastes of mastick or garlick; and the water fowl are best in bad weather, when the storms prevent their going to sea, and living upon fish. But as several of the animals abovementioned are only to be met with at the tables of the opulent, (1) Upupa Aldrov. Puputs. (2) Alauda, Turrolas. - (3) Scolopax, Segues. (4) Gallinago minor Aldr. Begasines. (5) An Columbalivia Gesner.r Xexels. (6) Pluvialis viridis &cinericea. Kilots C'juyes. (7) Turdus iliacus, Torts borrell. (8) Turdus pilaris. (9) Fringillago, Ulls de bou. (10) Fringilla, Pint ana. (11) Sturnus, Estornells. (12) Coturnix, Gualleras babarescas. (13) Ortygometra, an Rallus terrestris: (14) Grus, Gruas. (15) Anser ferus, Ojas salvages- (16) Numenius sive Aquata. (17) Phxnicopterus, Flamencos 34 INTRODUCTION, the plentiful provision of snails (l), with which na- ture has furnished this island, are of infinite service for the maintenance of the poorer families, who eat them boiled, after having been kept within doors long enough to lose their earthy taste. In dry wea- ther, when they are in their prime, they lurk in the chinks of the earth and crannies of the rocks, and commonly stick together in large clusters like grapes; which probably induced the Romans to give them the name of cochlea: cavaticw: but in wet moist weather, they leave these places of retirement in quest of food, and are frequently to be met with on the stalks of the asphodells, the shoots of the vines, and other vegetables; for what Pliny says of their never coming out of their caves, or feeding on greens, is intirely fabulous. Lib. viii. cap. xxxix. Having given these short hints relating to the na- tural history of Minorca, I shall now describe the temper and manners of the people, so far as may be necessary to introduce an account of their diseases. The natives of this island are commonly thin, lean, and well built, strong and active, of a middle stature, and an olive complexion. Their hair, for the most part, is black and curled; in many chesnut coloured; in some red. In a word, the young people are either of a sanguine or choleric constitution; while those of more advanced years become dry, meagre, and, what the ancients called atrabilious. Such is the na- tural impetuosity of their temper, that the slightest cause provokes them to anger; and they are equally incapable of forgiving and forgetting an injury. (1) Caragols,Boves, Mongetas, Caragolins INTRODUCTION. 35 Hence it is, that quarrels about the merest trifles daily break out even among neighbours and rela* tions; and family disputes are hereditarily transmit- ted from father to son. Thus, though lawyers and pettifoggers are very numerous in this country, yet there are still too few for the clients. They do not commonly live to so great an age as the inhabitants of more northerly countries; though, perhaps, they are equal in this respect to their near- est neighbours on the continent. Girls *oon arrive at maturity, and soon grow old. The menses, for the most part, appear before fourteen, and frequently at eleven years of age; in some they return twice a month; in others, every three weeks, and continue from three to seven days. Both sexes are, by consti- tution, extremelv amorous. They are often betroth- ed to each other while children, and marry at four- teen. The women have easy labours, and commonly return in a few days to their usual domestic busi- ness. Lest the family should become too numerous for their income, it is a practice among the poorer sort to keep their children at the breast for two or three years. Bread of the finest wheat flour, well fermented and well baked, is more than half the diet of people of all ranks. Rice, pulse, cuscassowe, vermicelli, herbs and roots from the fields and gardens, sum- mer fruits, pickled olives, and pods of the Guinea pepper, make up almost the other half; so that scarce a fifth of their whole food is furnished from the animal kingdom; and of this fish makes by much the most considerable portion. On Fridays, and other fast days, they abstain entirely from flesh; and 36 INTRODUCTION. during lent they live altogether on vegetables and fish, excepting Sundays, when they are permitted the use of eggs, cheese, and milk. Most of their dishes are high seasoned with pepper, cloves, cinnamon, and other spices; many of them are tinged with saffron; many sweetened with honey or sugar; and garlic, onions, or leeks, are almost constant ingre- dients. They eat a great deal of oil, and that none of the sweetest or best flavoured; using it not only with sallads^but also with boiled and fried fish, greens, pulse, &c. instead of butter. A slice of bread soaked in boiled water, with a little oil and salt, is the common breakfast of the peasants, well known by the name of oleagua. Their ordinary meals are verv frugal, and consist of little variety: but on fes- tivals, and other solemn occasions, their entertain- ments are to the last degree profuse and extravagant. The bill of fare of a country farmer's wedding din- ner would scarce be credited. This custom, with many others, they seem to have borrowed from the eastern nations. People of all conditions use wine at their meals; and though drinking to excess is not common, yet the vulgar are not exempted from private debauches, drains of anniseed water being too much in vogue. In summer the excessive heat obliges them to have frequent recourse to large draughts of cold, water, the greater part of which is but Aery indifferent; for the cisterns are seldom clean, and the water which the springs and rivulets afford is often brackish, and always hard; so that it is neither proper for washing, nor for boiling pulse, and leaves a stony crust on INTRODUCTION. 37 the sides of the teakettles, and other vessels in which it has been frequently boiled. Though the natives make three or four plentiful meals a day, yet they are generally costive; and many, in perfect health, have no occasion to ease themselves oftener than twice a week. They are so much addicted to the use of tobacco, as never to be without a pipe, either in their mouths or their pockets. In summer almost every one sleeps an hour or two after dinner, and some follow this practice throughout the year. A fourth of their time is made up of holidays, on which, though work is prohibited, sports and pas- times are allowed. A considerable part of those days is spent in the churches, or in processions: at night the more sedate divert themselves in their houses with music and cards; whilst the young men sere- nade their mistresses, in the streets, with the jarring musick of their guitars, and extemporary love songs of their own composing. In the interval between the harvest and the vin- tage there is a number of public diversions in dif- ferent places of the island. Whether because the people have then most leisure, or are in reality more cheerful from the serenity of the weather, as one of their proverbs* seems to hint, I shall not determine. To their horse and foot races,f notwithstanding the * En lo estiu tout hombre viu. In summer every body is alive. f On St. John's day, June the 24th, and the Sunday following. On St. Peter's day, June 29. On St. James's day, July 25. On St. Laurence's day, August 10. On St. Bartholomew's day,, August 24, and the 29th of the same month. On St. Gracia's day, September 8. D 38 INTRODUCTION. immoderate heat of the season, men, women, and children flock from all quarters, and expose them- selves to the sun in the middle of the day, dancing in the open air on the scorching rocks, and rattling their castanets in concert with the music of the guitar. Nor does their mirth finish with the day; as soon as it grows dark some pieces of pine tree are lighted as a torch in the middle of the street, where the crowd assembles, and continues dancing till morning. Every year, on St. Peter's day, June 29, they have likewise a diversion in Mahon harbour, which may properly be called a boat race; and one cannot ob- serve the eagerness of the boatmen, and the solici- tude of their friends on shore, without calling to mind Virgil's description of a similar contest on the anniversary of Anchises's funeral. JEn. v. ver. 129. In the carnival too, this people, however grave and serious at other times, freely indulge themselves in all manner of ludicrous sports and amusements; especially during the last week of it, when their revelling and extravagant mirth resembles more the ancient bacchanalia, than the diversions of any mo- dern civilized nation: for night and day the streets are filled with people in masks, and dressed in the most ridiculous habits; while the jarring sound of castanets, pipes and tabors, violins, guitars, and their more discordant vocal music, heightened with screaming, shouting, and every wild demonstration of intemperate joy, make almost one continued uproar. After this excess of mirth the fasts enjoined by their religion succeed, and continue till the expira- tion of lent; at which time a sheep or a lamb is slaughtered by each family; and on the joyful night INTRODUCTION. 39 which puts an end to this mortifying season, they endeavour, as it were, by one voracious meal to make up for the abstinence which they have been compelled to observe. This proves fatal to some, and would undoubtedly be so to many more, if nature did not prevent the effects of their intemperance, by a cholera morbus, or some such relief. The last thing to be taken notice of with regard to the manners of these islanders, is, that their great veneration for antiquity, and the little intercourse which they formerly had with other nations, have occasioned a number of old customs to be still kept here at this day. Thus, poetical disputes are much in vogue amongst the peasants.* One of them sings some extemporary verses on whatever subject he pleases, and accompanies them with the music of his guitar: he is immediately answered, in the same number of unpremeditated lines, by another, who endeavours to excel or ridicule him; and this alter- nate contest lasts, to the no small amusement of their attentive companions, until the wit of the rival poets be exhausted. These are the carmina amoebcea of the ancient Greeks, in imitation of which some of the pastorals of Theocritus and Virgil were written. In imitation of the ancients too, it is custo- mary for lovers to pelt their mistresses with oranges, as a mark of their regardjf though this is a diver- sion reserved for the carnival. The practice of throwing nuts and almonds at weddings, which Vir- gil mentions (Eclog. viii,) is likewise retained. * These verses are called glossos, and those who excel in making them, glossodors. \ Malo me Galatea petty lasciva puella, &c. Virg. Eck>g. iii. 40 INTRODUCTION. Soon after a person is deceased his friends and re- lations assemble in the house to bewail their loss, and commemorate his virtues, weeping and howling with all the seeming agonies of distress; and that this was an ancient custom, appears by the elegant and pathetic funeral dirge, which we find in Lu- cretius (lib. vi.) And in this island, as in the southern provinces of France, and in Italy, the dead bodies are not nailed up in coffins, but carried in an open litter to the grave, which, we learn from authors, was also practised, on some occasions, among the old Romans.* Another instance of their inviolable attachment to ancient usages, is the manner in which the women wear their hair; for, contrary to the cus- tom of all the neighbouring countries, excepting Majorca, they force it with fillets to the back part of the head, and bind it in a queue of a considerable length. When the natural locks are not long enough for this purpose, false ones are added to supply the deficiency; ibr nothing is reckoned more unbecoming than to be destitute of a tail, or to appear with one too short. But not to be tedious with too many in- stances, I shall only add, that in the use of the sling the present inhabitants of Minorca are no less dex- trous than their forefathers, who are said to have driven the Romans off their coasts by vollies of stones (Flor. Epitom. lib* iii.) The shepherds, or those that tend the cattle, seldom miss such of them as fall under their displeasure; and by this means they have their flocks and herds so much at^command, that even the cracking of the empty sling is sufficient * See Cornelius Nepos on the burial of T. Pomponius Atticus, and Lispius's Notes on this passage. INTRODUCTION. 41 to intimidate them, and bring them together in such parts of the pasture as their keeper pleases: and as the cattle are often maimed and hurt by the severe chastisement inflicted by means of this instrument, the farmers find it expedient to forbid the use of it to such of their servants as are of a cruel and mis- chievous disposition. The mentioning of their cattle puts me in mind of two other singular practices which prevail here, viz. that of castrating animals by bruising their testicles, which, we learn from Albucasis (Chirurg. p. 2. cap. lxix.) was customary among the Arabians; and the way of slaughtering oxen, by thrusting a knife into the medulla spinalis, immediately behind the occiput, which is so much preferable to the method of knocking them on the head, that it is surprising other nations do not fall into it. Having gone through what I intended to remark in relation to the natives, I should next, according to the plan of this introduction, give a circumstantial account of the diet, and common way of life, of the British soldiers in this island; but as this would be a disagreeable task, I shall only observe, that the excess of drinking is, among them, an universal vice, confirmed into a constant habit. Pudet hxc opprobria nobis, &c. But however different the Spaniards be from the English, in their meat, drink, exercise, affections of the mind, and habit of body; yet the health of those of both nations is equally influenced by the seasons. An epidemical distemper seldom or never attacks one class of inhabitants, while the other remains un- hurt; and surprising as it may appear, it is never- D 2 42 INTRODUCTION. theless true, that the peasants, who are remarkable for temperance and regularity, and the soldiers, who, without meat and clothes, frequently lie abroad drunk, exposed to all weathers, have diseases almost similar, both as to their violence and duration. Hence it is evident how far the power of the air is superior to that of the other nonnaturals in produc- ing disorders of the animal economy. The diseases which, from their frequency in this island, I reckon endemial, may be divided into two classes; the epidemic, or such as affect numbers to- gether at particular seasons; and the sporadic, which are equally common at all times of the year. To the first belong the rash, essere, cholera morbus, tertian fevers, fluxes, pleurisies, peripneumonies, erysipela- tous fevers, and those that are accompanied with ca- tarrhs: to the second, obstructions of the abdominal viscera, the haemorrhoids, ulcers of the legs, ruptures^ inflammations of the eyes, and nephritic pains. With respect to the epidemics, it may riot be im- proper to observe in general, that acute fevers are more frequent here than, in England; that they are much more violent, but of shorter duration; that they oftener terminate completely by a manifest crisis; and in all respects agree much more exacdy with what the ancients have said concerning such evacuations, and the periods in which they usually happen. The most common diseases of the sporadic kind are obstructions, indurations, and swellings of the glandular viscera in the lower belly; together with wind in the first passages, and bad digestion. The causes of these obstructions seem to be, in the first INTRODUCTION. 43 place, a scarcity of good water; for, as Hippocrates has well observed,* Where there are no rivers, and the inhabitants are obliged to drink stagnating, ill- scented well water, such must needs hurt both the belly and the spleen. And it is remarkable, that large spleens, like those described by Trallianus (lib. viii, cap. xii,) and hard tumefied livers, are not only com- mon to the human species here, but also to brutes; particularly the sheep that feed on the northeast side of the island, where the waters are very brack- ish; though the butchers, to whom this fact is well known, generally ascribe it to their eating the horse- mint and pennyroyal, which abound in the pastures. Secondly. The intense and long continued sum- mer heats, by dissipating the finest particles of the animal juices, necessarily leave the rest of a grosser and more earthy nature. And thus is a large pro- portion of that kind of matter generated in the blood, which the ancients called atrabilious; and this being deposited in the viscera, occasions the above- mentioned obstructions. See Boerhaave's Aphorisms de Melancholia. Thirdly. Another cause of these obstructions is the frequency of acute diseases, and more especially of tertian fevers, which, as they frequently relapse, and go off with imperfect crises, weaken the tone of the chylopoetic viscera, and at last terminate in hard scirrhous tumors of the liver and spleen. It is likewise probable that their living so much upon pulse and crude vegetables, the abuse of spi- rituous liquors, their high seasoned diet, their pas- sionate temper, and immoderate use of venery, co- * De Aere, Aquis, et Locis, sub finem. 44 INTRODUCTION. operate with the causes just now mentioned, in pro- ducing the same effects. But such is the goodness of Providence, that eve- ry climate seems to yield domestic antidotes for the endemial diseases.* Accordingly we find that this island abounds with whey, honey, summer fruits, gentle cathartics, hieracea, cichoracea, and all that class of plants and roots with aperient saponaceous juices, which antiquity has recommended as specifics or approved remedies in obstructed bowels. But in these distempers it is universally allowed, that nothing is of so much advantage as the haemor- rhoidal flux; and therefore, however frequent and troublesome the piles may be in this climate, they ought to be considered rather as a benefit of nature, and a remedy, than as a misfortune, or a disease; more especially as they prevent pleurisies and peri- pneumonies, according to the doctrine of Hippo- crates. De Humor. & Epid. lib. vi. Baglivi f tells us, that at Rome ulcers of the legs are almost incurable, and wounds in them difficult to heal; while the like accidents on the head are quickly cured without any trouble. The same thing happens here, insomuch that it is a proverb among the natives, " Minorca is good for the head, but bad "for the shins."\ This, perhaps,- is owing partlv to the redundancy of atrabilious particles in the blood, which naturally flowing into the inferior branches of the aorta, constantly keep open any outlet through * See the quotations from Ray and Benorovinus, in Der- ham. Phys'u o Theolog. Book x. | Prax. Med. lib. i. ;.. 10J \ Minorca es bo de Cap y mal de Camas. INTRODUCTION. 45 which they have once found the way; partly to the large obstructed viscera, compressing the vena cava, and hindering the free return of the fluids from the inferior extremities. Hence we find, that ulcers of the legs, with black cicatrices (such as may daily be seen among the soldiers and Spaniards), are men- tioned both by Hippocrates (De Morb. Intern.) and Celsus (lib. ii, cap. \ ii,) as the effect of over- grown spleens. And now it plainly appears why ruptures are so common in this place; for the other bowels being swelled beyond their natural size, the intestines are too much confined; and from the nature of the aliment, being frequently distended with wind, it is not to be wondered at, that they often push through the rings of the abdominal muscles. In so hot and dry a country as this all the parts of the body are very subject to topical inflammations: But the eyes are most particularly affected in this way; which seems to be occasioned chiefly by the strong dazzling light reflected, during the summer season, from the white rocks and sand; to which we may perhaps add, that the floating particles of salt, dust, and minute insects, wherewith the air often abounds, do likewise injure the tender texture of this organ, and give rise to ophthalmias, or increase them. Whatever dissipates the finer parts of our fluids, and increases the proportion of earth and fixed mat- ter (and several such causes I have already had oc- casion to take notice of), will be apt to produce sand and gravel in the urinary passages; though it is probable, that the calculous concretions and nephri- 46 INTRODUCTION. tic pains are chiefly owing to the waters, which, as I formerly observed, are mostly hard and brack- ish, and let fall a large quantity of stony sediment after boiling. The convulsion of the lower jaw in children ought likewise to be reckoned among the sporadic dis- tempers. And as it is both very frequent and fatal in this island, and some of the neighbouring coun- tries, I shall give a description of it from Hyacin- thus Andreas, a Spaniard, who, about the end of the last century, published an abridgment of Rive- Rius, under the name of Praxis Medica Gotholano- rum, with very little addition of his own, excepting an account of this disease, which most other authors have omitted. In hac urbe nostra Barchinonensi af- fictantur plurimi infantes, adeo feroci convulsione mandibular inferioris, ut ea apprehensi, nullo possint motu illam movere, et abhinc suctus lactis impeditur omnino. Emergit hoc malum ex causa humiditatis re- gionis, et potissimum si matres,prctgnatioms tempore, minus sobrie vixerint; et usa fuerint alimentis humi- dis, et potibus gelidarum eximzis: et quanquam istas duas inveniamus causas, adeo manifestos, existimo ta- men potius hanc cladem insolescere, ex peculiari call vel astrorum infiuxu, quam ex illis duabus: Nam in plurimts aliis humidis regionibus laute bibunt mulieres, et tamen non afflictantur infantes (ita attestantur medicij morbo isto diro, quemadmodum in hac nostra civitate, in qua tot interfcit mala ista convulsio, ac variola; aut morbilli. Unde si in toto orbe premantur infantes unico tyranno, nempe variolis, in hac qui- dem civitate, duplici confictantur, sciz. variolis et convulsione mandibularum, quae a nostris mulier- INTRODUCTION. 47 cults et obstetricibus vocantur barrettas, in quorum periculum incurrunt recenter nati, usque ad nonum sui nativitatis diem, eoque transacto, omne discrimen cessare docuit semper experientia. It is needless to add the remedies prescribed by our author, who in- genuously confesses, that the disease is so seldom curable, that in twenty years' practice he had scarce known six recover. To these we may add the following hurts arising from endemial causes. The children and peasants are often ulcerated with the caustic milky juice of the figtrees and spurges, which are common in the fields: in drinking corrupted waters sometimes leech- es are swallowed, which I have known to occasion extraordinary symptoms, such as coughs, nausea, spitting of blood, &c. to the great surprise of both the physician and patient, who were entirely igno- rant of the cause of these complaints. The pastinacse marinae, and aquila, wound dangerously with the stings in their tails; and the scorpius, scorpaena, and draco, with the prickles of their back; (for which reason the fishermen are obliged by law to cut off these weapons before they bring the fish to market). In the hot weather the viper, the land scorpion, and the small black field spider, are reckoned poisonous. In the spring the hedgehogs, fagrantes astu ve- nereo, are said to pollute the waters, to which they have access, and thereby occasion a strangury and priapism to those who drink of them: and at this season the flesh of these animals has the same effect, though it is wholesome and innocent enough at other times of the year. But as accidents of this 48 INTRODUCTION. class rarely occur, it is sufficient barely to mention them. In the opinion of the natives no diseases are more frequent here than witchcraft, charms, and evil spi- rits. Those nevertheless, I shall entirely omit, hav- ing neither leisure nor inclination to enlarge upon the craft of the clergy, and the credulity of their flocks: but whoever desires to see this subject co- piously handled, may consult the learned father Feijoo, who, in his useful and elaborate volumes on vulgar errors, has taken occasion to expose the tricks of those pious jugglers, who pretend to exorcise evil spirits, together with several other impostures of the same nature. These particulars I thought it necessary to pre- mise, before we enter on the history of the epidemi- cal diseases. In excuse for whatever errors I may have committed in this mixed essay, I hope I may be allowed to plead, that I wrote it in a part of the world, which afforded me very little assistance either from men or books. Qualemcunque igitur venia dignare libellum Sortis et excusa conditionem mese. Ovid. Minorca, An. Dom. 1747. AN ESSAY ON THE EPIDEMICAL DISEASES IN MINORCA. CHAPTER I. Of the Weather from the Tear 1744 to 1749. I AM sorry that it was not in my power, for want of conveniency and proper instruments, to determine exactly the weight of the air, the quantity of rain, and the force of the winds: notwithstanding which omissions, I flatter myself, the following short ac- count of the principal variations of the weather, ta- ken from a diary regularly kept, with very few in- terruptions, will neither be entirely useless nor unacceptable: and, in order to make it better un- derstood, I shall premise a few explanatory obser- vations. In the first place, in speaking of days and months, I use the old style, as is customary among the En- glish in Minorca; though- the natives reckon by the new: and where it appearechiecessary to distinguish E 50 OF THE WEATHER. the forenoon from the afternoon, I have annexed a. m. or p. m. to the particular days. Secondly, Wherever a rainy day occurs, without any dots after it, the reader will be pleased to take notice, that only drizzling rain, or a slight shower happened on that day: but if two dots be placed after it, in this manner • • it signifies one or more smart showers to have fallen: if three dots • • • great rains: if four • • • • extreme heavy rains, or rather floods of water. Thirdly, Wherever the thermometer is mentioned, it is to be understood of a large mercurial one, gra- duated according to Fahrenheit's scale, and kept in a proper place within doors; except when I describe the heat of the sun's rays; which was measured by a smaller instrument of the same kind, hung out at an upper window, in the open street, at a considerable distance from the walls of houses. Both these ther- mometers, being dipt in snow, fell to the 3 2d degree. Both were raised to the 96th, 97th, or 98th degree, by the natural warmth of persons in health. Nor did I observe any other difference between them, ex- cepting that the mercury in the smaller was sooner affected by heat or cold, and consequently a little quicker in its motions; which occasioned its being found sometimes a degree higher in summer, and as much lower in winter, than the quicksilver in the large thermometer. Fourthly, The height of the thermometer, at a medium, during each month, is calculated from ob- servations made about three o'clock in the afternoon, when the mercury is commonly higher by one or two OF THE WEATHER. 51 degrees in winter, and two or three in summer, than in the mornings and evenings. Fifthly, The difference between the heat of air warmed by the direct rays of the sun, and that in the shade, is at a medium in summer, about 13 degrees. Whenever it was remarkably greater, notice will be taken of it; as likewise of the most extraordinary heights to which the mercury rose, when the ther- mometer was exposed to the sun, at other times ot the year. Sixthly, The mercury seldom or never sinks be- low the 48th degree in Minorca, except when sharp winds blow from the north, which cause the weather to seem as intensely cold as it is in England, when the thermometer has been ten degrees lower. And upon the descent of heavy rains, particularly in the autumn, the cold affects us much more sensibly than one would imagine, from the alteration of the ther- mometer. These things being premised, I proceed to de- scribe the most remarkable changes of the weather, in each month, during the period of time that pro- duced the epidemical diseases, which are the subject of this treatise. A.D. MDCCXLIV. January was mild and temperate in the begin- ning: but after the rains, about the middle of the month, it continued, for the most part, cold and cloudy. Rainy days, 1, 6, 9, • • 10, • • 11, 14, 15, • • • • 19, • • with hail, 20 with hail, 24, 27, 30. The first days of February were cloudy, cold, 52 OF THE WEATHER. 1E44. rainy, and stormy: from the 4th to the 19th the weather was moderate and seasonable, without ex- cessive rains or immoderate cold: from which to the 26th it was fair and warm: but afterwards to the end of the month, rough and stormy as in the be- ginning. March, during the first week, was sometimes warm and sometimes cold : but in the three last weeks piercing winds blew constantly from the north, with frequent rains, and sometimes hail. The weather continued colder, and more disa- greeable than usual, till much rain had fallen about the middle of April; the remainder of which month was mostly fair and temperate. The first fortnight of May was likewise fair and temperate; the latter part of it dry and wTarm, with- out any rain. June was clear, calm, dry, and sultry, as this and the two following months are constantly observed to be; the weather varying much less in these than in the other months. Rainy day, 9. In July the northerly winds were higher and more frequent than ordinary, insomuch, that on some days the cold was more troublesome than the heat; nor do I ever remember to have felt so little heat in this month in Minorca. Rainy days, 6, at night • • • • with thunder and lightning, 17, p. m. Coldest day, 8. Therm. 70. > Height at a Hottest days, 21, 22, 31. 80.5 med. 76j|. During the first days of August the northerly winds continued; but the rest of the month was 1744. OF THEWEATHER. 53 either calm, of the breezes came from the south, the air being very hot and sultry. Rainy days, 2, a. m.' 14, a. m. Coldest days, 3, 4. Therm. 73. ? Height at a Hottest days, 27, 28, 29, 30. 80. 5 med. 77-^. In September the weather is always very unequal; fair intervals, and short violent storms reciprocally succeeding each other: but this year the anniversary rains were not so constantly attended with northerly winds as they commonly are. Rainy days, 7, a. m. • • • • with thunder and light- ning, and at night ••••!!, at night, • • • • 15, at night, • • • • 18, at night, • • • • 19, at night, 22, at night, • • • • with lightning, 23, at night, with lightning. Coldest days, 17, 26. Therm. 71.} Height at a Hottest days, 1, 2, 3, 76.$ med. 73^. In the first part of October the winds were mostly from the north or northwest, the weather variable and unsettled: but from the 14th to the end of the month it was calm, warm, and fair. Rainy days, 2, at night, 4, at night, • • 5, at night, • • 13, a. m. and p. m. • • • • Coldest day, 14. Therm. 65. > Height at a Hottest days, 1, 2. 71.5 med. 68JL.. November was remarkable for bad weather. All the first day, and the second before noon, it blew violently from the north, with heavy rain: from the 7th to the 22d the weather was constantly cold, cloudy, and stormy, with hail, rain, and high winds, E2 54 OF THE WEATHER. 1745. from the north. After a few fair days this month ended stormy, as it began. Coldest day, Therm. 50. ) H . med 56< Hcrttest day, 1. 67-5 & From the first of December to the 13th the air was cold, but for the most part clear; the wind north or northwest. But at that time shifting suddenly to northeast, a violent storm began, and continued with great fury to the 17th, more especially in the nights, with hail, rain, and flakes of snow. On the 18th the weather again cleared up; but on the 21st it became cold, stormy, and rainy; and, excepting one fair day or two, it continued so to the end of the month. Coldest days^ 14, 15. Therm. 44. ~> Height at a Hottest days, 26, 31. 57-5 med. 5\±. A. D. MDCCXLV. This year began with strong piercing northerly winds; nor did the coldness of the air decrease much before the latter end of January, though the weather was mostly calm and clear with sunshine. Rainy days, 6, at night, • • with hail, 13, at night, ■ • 15, at night, • • 26, at night, • • • • Coldest day, 6. Therm. 43. > Height at a Hottest days, 26 to 31. 57.$ med. 52. The first week of February was pleasant and se- rene; the remainder was mostly cold, cloudy, and overcast. Rainy days, 8, p. m. • • • 11, at night, • • • 15, • * 21, • • • 24, a. m. • • • 25, 28, • • 1745. OF THE WEATHER. 55 Coldest day, 26. Therm. 46. ? Height at a Hottest days, 7, 8. 61-5 med. 55. Except the first day, which was windy, contrary to custom, March was warm, calm, and dry, without any storms, the winds being mostly from the south or west. Rainy days, 22, a. m. 23, ■ • Coldest day, 1. Therm. 51.? Height at a Hottest day, 12. 63. J med. 59. April was likewise warm and temperate, but some- what more windy and rainy than the preceding month. Rainy days, 3, 8, 23, • • • 27, 28 Coldest day, 17. Therm. 58 > Height at a Hottest days, 25, 26. 65-5" med. 61f|. On the 19th the therm, in the shade 62, exposed to the sun 80. The heat of the weather increased greatly in May, notwithstanding some unseasonable rains, and nor- therly winds, about the end of the month. Rainy days, 1, 7, 8, ■ • 16, • • 23, at night, 24, p. m. • • • • 25. Coldest days, 1, 2. Therm. 62.? Height at a Hottest day, 17. 74.$ med. 68-^.. On the 4th the therm, in the shade 65, exposed to the sun 88. The beginning of June was likewise unseasonable, with rains and northerly winds. The rest of the month was calm, dry, and hot, as usual. 56 OF THE WEATHER. 1745. Rainy days, 4, a. m. • • • • and at noon, • • • • 7, at night, Coldest days, 4 to 7. Therm. 69. ? Height at a Hottest day, 28. 82. $ med. 73|. On the 28th the therm, in the shade 82, exposed to the sun 98. July was a little more temperate than usual, the heat of the air being frequently allayed by breezes or showers. Rainy days, 16, a. m. • • • 17, a. m. • • ■ • and p. m. • • • • and at night, • • • • with thunder, 27, p. m. • • 29, at night, • • • • with lightning. Coldest days, 21, 22. Therm. 75. \ Height at a Hottest days, 6, 25, 26. 80. $ med. 77if. On the 7th the therm, in the shade 79, exposed to the sun 100. 25th therm, in the shade 80, exposed to the sun 96. August, except the first three days, was excessive hot and sultry, till the latter end, when the air was refreshed by brisk northerly breezes. Rainy days, none. Coldest days, 1, 23 to 27. Therm. 74. ) Height at a Hottest day, 9. 82.$ med. 77ff. On the 9th the therm, in the shade 82, exposed to the sun 95. The beginning of September was very sultry, though not always serene. But from the 12th to the end it was constantly either cloudy, rainy, or stormy with violent squalls from the north. 1745. OF THE WEATHER. 57 Rainy days, 12, at night, • • • • 13, at night, • • • 14, at night, with thunder, 16, p. m. • • • • and at night, • • • ? with thunder, 17, p. m. • • • • 18, a. m. • • • and at night, • • • • with thunder and lightning, 19, a. m. • • • • and at night, • • • • 20, • • 27, * • • • at night, with thunder and lightning, 28, • • 30, at night, with lightning. Much lightning in the nights of the 20th, 21st, and 22d. On the 24th the therm, in the shade 73, exposed to the sun 89. The weather during October was fair, pleasant, and serene, except the rainy days, and some few others, the winds being mostly moderate and northerly. Rainy days, 1, a. m. 3, a. m. • • • • 7, at night, • • • • with thunder and lightning, 8, a. m. • • • • 17, at night, with lightning, 25, 26, at night, • • • 27, a. m. • • • Coldest days, 29, 30. Therm. 61.? Height at a Hottest days, 1, 2. 69.$ med. 65§f Almost all November was either cloudy or wet. From the beginning to the 24th the wind was mostly from the south, or southwest. Afterwards it changed to the north, and the air continued cold and damp to the end of the month. Rainy days, 2, 5, 7, at night, • • • 10, a. m. and p. m. • • and at night, • ♦ • 11, at night, • • 14, 15, at night, • • • with hail, 21, a. m. • • 26, • • • 27, • • 30, • • 58 OF THE WEATHER. 1746. Coldest day, 27. Th. 50.? „. ,. . o m, ,R 6 Hottest day, 8. 65. $ HeiSht at a metL 58^' The first week of December was wet and cold, with high easterly and northerly winds. The re- mainder was somewhat more temperate and calm, the winds being, for the most part, southwest or southerly. Rainy days, 1, • • • 2, • • • 5, at night, • • • 7, p. m. • • 12, • • 18, • • 20, p. m. • • and at night, • • 21, • • Coldest days, 5, 6, 9. Therm. 48. \ Height at a Hottest day, 27. 60. $ med. 53if A.D. MDCCXLVI. The greatest part of January was fair and clear, with cold easterly winds. Rainy days, 6, • • • 10, • • 11, a. m. • '23, 31,* •• with hail. Coldest days, 7, 12. Therm. 48.? Height at a Hottest day, 28. 57.$ med. 52§f During February the weather resembled that of the preceding month, though somewhat colder, and more windy. Rainy days, 3, • • 6, a. m. • • • 7, a. m. • • 23, a. m. • • 28, • • Coldest days, 2, 3, 15. Therm. 45. ? Height at a Hottest day, 20. 57. $ med 5 ljf. On the first of March there was a remarkable storm from the north, with flakes of snow in the evening. Next morning the fields were covered with 1746. OF THE WEATHER. 59 snow a foot deep, which melted away soon after sun- rising. But some more fell the following night, and continued upon the ground for three days ere it melt- ed ; which is so extraordinary a phenomenon in this part of the world, that it had never before happened above once or twice in the memory of man. From the 5th day the cold gradually decreased to the 15th, and afterwards, to the end of the month, we had fine moderate weather. Rainy days, 13, 14, • • 28, a. m. • • • 30, a. m. • • 31,- • Coldest days, 3, 4. Therm. 42. ? Height at a Hottest days, 24, 27, 30, 31. 60.$ med. 54 -^. In April.the weather was exceedingly changeable, and often rainy or overcast. Rainy days, 3, at night, • • • • 4, a. m. • • • • 20, p. m. • • • • 11, • • • with hail, 13, • • • • with a storm of wind, 14, 17, at night, • • • • 18, a. m. • • 23, • • Coldest day, 13. Therm. 54.? Height at a Hottest day, 30. 68.$ med. 59||. On the 3d th. in the shade 57, exposed to the sun 83. 29th 65, 88. May was calm, serene, and seasonable, seldom ob- scured with clouds or rain, until it drew near the end. Rainy days, 9, 21, 24, a. in. • • 29, 30, p. m. • • • • with thunder and lightning, and at night, • • • • with thunder and lightning. Coldest day, 11. Therm. 64. ? Height at a Hottest days, 4, 5, 18, 20. 70. $ med. 68T\. 60 OF THE WEATHER. 1746. June, as usual, was dry, sultry, and serene. Rainy day, 15th. Coldest day, 11. Therm. 69. ? Height at a Hottest days, 26, 27. 79. $ med. 73if. The heat gradually increased from the end of June to the 20th of July, being very troublesome and un- easy, even to those who never exposed themselves to the sun. But during the latter part of the month, it was mitigated by daily breezes. Rainy days, 28, a. m. 29, a. m. and at night, 30, a. m. • • • • with thunder and lightning. Coldest days, 8, 29, 30. Therm. 77. ? Height at a Hottest clay, 19. 87. $ med 80ff August was more temperate than the preceding month, the heat being somewhat allayed by the nor- therly winds. Rainy days, 1, a. m. 19, a. m. 27, p. m. • • • • with thunder and lightning, 31, at night, • • • • with thunder and lightning. Coldest day, 29. Therm. 70. ? Height at a Hottest day, 15. 81.$ med. 76||. September began with storms of wind and rain; from the 4th to the 14th it was clear and warm; from which to the end of the month the sky was constandy either darkened with heavy rains, or was tempes- tuous with strong northerly winds; the Aveather be- ing much colder than usual at that season of the year. Rainy days, 2, p. m. • • • • with thunder and lightning, 3, a. m. • • • • with thunder and lightning, 1746. OF THE WEATHER. 61 and hailstones of an inch diameter, 15, a. m. 16, a. m. • ■ and at night, • • • • 17, * * * • with thun- der and lightning, 18, • • 19, • • 20, at noon, • • -and at night, • • • • 22, p. m. • • 23, at night, • • • • 24, • • and at night, • • • 26, and at night, • • • • 28, at noon, • • • • Coldest days, 22, 26. Therm. 58. ? Height at a Hottest day, 13. 74.$ med. 67^. The first and last week of October were mostly pleasant and serene: the two intermediate weeks were rainy and overcast; and the whole month was uncommonly cold, with northerly winds. Rainy days, 8, p. m. and at night, • ♦ • • 9, at night, • • • 10, • • • at night, • • • • 14, p. m. • • 18, 20, p. m. • • • • 21, • • • • with thunder and lightning, 22, p. m. • • • •. and at night, • • • • 30, a. m. • • • • with hail. Coldest days, 8, 9. Therm. 54. ? Height at a Hottest day, 1. 68.$ med. 58ff During November the weather was calm and sea- sonable, with much sunshine on the days free from rain. » Rainy days, 1, at night, • • 2, • • • and at night, • • • • 3, at night, • • • • 4, • • • 5, • • 12, at night, • • • 14, • • 17, a. m. • • 19, a. m. • • 26, p. m. • • • • Coldest day, 20. Therm. 54.? Height at a Hottest days, 28, 29. 62. $ med. 57l£. In December there was no extraordinary cold wea- ther, and very seldom high winds; nor was the se- renity of the sky much interrupted by clouds or rain. F 62 OF THE WEATHER. L747. Rainy days, 14, • • • 15, • • 29, at night, • • * 30, • • 31, • • • and at night, Coldest days, 11 to 15. Therm. 54. ? Height at a Hottest day, 59. $ med. 56. A.D. MDCCXLVII. The weather of January was like that of the pre- ceding month, but somewhat more wet and cold in the beginning. Rainy days, 1, a. m. • • • 2, p. m. • • and at night, ■ • • 4, at night, • • 12, • • 14, • • Coldest day, 5. Therm. 50. ? Height at a Hottest days, 20, 28. 59.$ med. 55-^. During the first fortnight of February we had warm, fair, summerlike weather: the third week was rainy and tempestuous, with some hail and snow; the fourth very changeable, the sunshine be- ing often interrupted by showers. Rainy days, 16, p. m. • • • and at night, • • • • 17, a. m. • • and p. m. • • with hail and snow, 19, at night, • • • 21, • ♦ 24, at night, • • 25, 27, 28. Coldest day, 18. Therm. 50. ? Height at a Hottest days, 5, 10. 62.$ med. 55|f. On the 4th the therm, in the shade 61, exposed to the sun 78. From the beginning of March to the 21st the weather was cold, and often wet; the winds mostly from the north, and sometimes very boisterous: the remainder of the month was fair and moderate, with westerly or southwest winds. Rainy days,. 1, 2, • • • 3, • • • and at night, • • • 9, 1747. OF THE WEATHER. 63 p. m. 14, a. m. • • 17, at night, • • • 19, a. m. • • 20, a. m. • • • with hail. Coldest days, 6, 13 to 17. Therm. 50.? Height at a Hottest day, 30. 63.$ med. 54-if-. April was fair and dry, but sometimes very win- dy ; in the fore part of the month especially; and the wind being then at north did great damage to the fields and vineyards. About the middle and to the end the southeast prevailed. Rainy days, 9, at night, • • • 10, at night, • • Coldest days, 2, 3. Therm. 56. ? Height at a Hottest days, 27 to 30. 68.$ med. 61||. Betwixt the 1st and the 9th of May the weather was often disagreeable, with rain, clouds, or much wind. But almost all the rest of the month was clear, calm, and warm. Rainy days, 1, 6, p. m. • • • 7, p. m. • • • • with thunder and lightning, 8, at noon, • • • 28, p. m. with thunder and lightning, 29, a. m. • • Coldest days, 1, 7 to 10. Therm. 67. ? Height at a Hottest day, 31. 75.$ med. 71. On the 4th the therm, in the shade 70, exposed to the sun 88. June was hot and dry as usual. On the 27th of the month dark clouds suddenly rose from the north, a little before sunset, and a storm of wind succeed- ed, which lasted all that night. Rainy day, 23, a. m. Coldest day, 23. Therm. 71.? „ . , Hottest days, 26, 27. 80.$ Height at amed.76. 64 OF THE WEATHER. 1747. On the. 24th the therm, in the shade 71, exposed to the sun 94. During July hot suffocating winds with unwhole- some vapours, from the south and east, were pre- dominant. Rainy days, 6, a. m. • • • 7, a. m. • • • 18, at night, • • • • 26, p. m. • • • Coldest day, 8. Therm. 73. ? tr . , . . , _. , Hottest day, 21. 84. $ HelSht at a med' 79A- On the 12th the therm, in the shade 80, exposed to the sun 99. On the 21st the therm, in the shade 84, exposed to the sun 100. The beginning of August was intolerably hot; nor was the rest much more temperate, though it rained plentifully about the middle and end of it, the winds being most commonly from the east and southeast. Rainy days, 9, p. m. 12, at night, • • • • with thun- der and lightning, 15, at night, • • • • with thun- der and lightning, 16, p. m. • • • • with thunder and lightning, 28, at night, • • • • 29, a. m. with thunder and lightning, 30, a. m. • • • and much lightning at night. Coldest day, 30. Therm. 74. ? Height at a Hottest days, 8, 10, 11. 84.$ med. 80^. On the 8th the therm, in the shade 84, exposed to the sun 100. On the 15th the therm, in the shade 79, exposed to the sun 98. The slight showers which fell first in September, rather increased than allayed the warmth of the air: but the storms of wind and rain about the middle of the month put an end to the hot weather for that season. 1747. OF THE WEATHER. 65 Rainy days, 8, 11, a. m. 13, p. m. and at night, .... 14? . . . . and at night, • • • • 18, at night, • • • with thunder and lightning, 19, •'• • and at night, • • • • 20, • • • 21, at noon, • • • with hail, 23, p. m. and at night, • • • 24, a. m. • • • and at night, • • • • 25, • • 28, p. m. • • • and at night, • • • • with thunder and light- ning, 29, • • • and at night, • • • • 30, a. m. • • • • Coldest day, 21. Therm. 63. ? Hei£rh, atamed 7222 Hottest day, 10. 81.$ "eight at a med. 7^. On the 1st, theth. in the shade 79, exposed to the sun 98. 2d, 80, 100. 10th, 81, 98. Except a shower or two, and a storm of wind from the northeast on the 21st, October was entirely calm and serene. Rainy days, 4, p. m. • • and at night, • • 17, p. m. • • 19, p. m. • • 21. Coldest days, 19, 25, 27, 28. Therm. 62. } Height at a Hottest days, 10, 11, 12, 14. 70. $ med. 65fi. On the 2d, the th. in the shade 67, exposed to the sun 90. 9th, 69, 86. 23d, 64, 83. 26th, 63, 88. Nor was November less serene, though sometimes more windy, especially at the close of the month, when it blew violently from the north. Rainy day, a. m. • • • with hail. Coldest day, 27. Therm. 51. ? R { h d 6Q 2 Hottest day, 2. 67.$ 5 30 On the 16th, the th. in the shade 59, exposed tp the sun 84. 22d, 62, 82. 27th, 51, 74. 28th, 54, ?9, F? >4>o OF THE WEATHER. 1748. From the 1st to the 6th of December the wind blew strong from the southwest; as it did from the southeast from the 20th to the 24th: the other days of this month were mostly fair, calm, and agreeable. The whole of the month was uncommonly warm for the season, except the last day, when the wind changed to the north. Rainy days, 8, a. m. • • • and at night, • • 9,12, 14, • • with thunder and lightning, and at night, • • 17, • • 24, a. m. • • • • 25, p. m. • • • 28, p. m. • • Coldest day, 31. Therm. 53. ? „ . . , Hottest days, 3, 5. 64.5 HeiSht at a med- 58TT- On the 5th the th. in the shade 64, exposed to the sun 88. 6th, 63, 84 A. D. MDCCXLVIII. The sharp northerly wind, which began on the last of December, was attended with some hail and snow on the 4th, and continued to the 6th of January. It then shifted to the northwest, and though the wea- ther was mostly fair and dry, yet the air continued cold till the rains fell, near the end of the month. Rainy days, 2, a. m. • • and p. m. • • 5, a. m. • • • 6, at night, • • 15, at noon, • • 18, at night, • • 22, at night, • • • 23, and at night, • • • 25, p. m. • • Coldest day, 4. Therm. 43. ? TT . Hottest day, 22. 57. $ Height at a med. 5 l|f. On the 8th the th. in the shade 44, exposed to the sun 64. 18th' 50, 68. The weather continued mild and temperate to the 17th of February, though the rains that fell in the second week were accompanied with high southerly 1748. OF THE WEATHER. 67 and southeast winds: afterwards, to the end of the month, we had dry, cold, north and northwest winds, which did much mischief to the corn. Rainy days, 6, at night, 8, 9, • • 10, a. m. • • and p. m. • • • 11, a. m. • • • 13, a. m. 15, at night, 16, • • and at night, • « 18, p. m. 25, at night, • • • with hail, 26, p. m. • • and at night, • • Coldest day, 21. Therm. 48.? ,, . w . , t„ tr ** * j * o ,n ^ Height at a med. 55. Hottest days, 6, 8. 60.3, ° Onthe 1st the th. in the shade 56, exposed to the sun 76. 19th, 52, 78. 24th, 54, 80. In the beginning of March the weather was win-. dy, but not very cold : between the 10th and 23d we had violent storms of wind, rain, and hail, with fair intervals. The end of the month was remarka- bly pleasant and serene. Rainy days, 7, p. m. with a little hail, 10, a. m. 11, at night, • • • 12, a. m. • • and p. m. • • with hail and snow, and at night, • • 13, at night, 14, p. m. 16, p. m. and at night, • • • with thunder and light- ning, and snow, 17, • • • 18, • • • and at night, • • 19, p. m. • • • and at night, • • • • 20, p. m. 21, 30, p. m. Coldest days, 19, 21. Therm. 50.? Height at a Hottest days, 27, 29, 30. 63. $ med. 55^-. On the 14th the th. in the shade 51, exposed the sun 76. 27th, 63, 82. April was cold and stormy from the 14th to the 20th; all the rest of the month was calm, clear, and warm, except the 25th, when it rained, and blew fresh from the northwest. Rainy days, 6, at night, 14, p. m. • • • with thurr- 68 OF THE WEATHER. 1748. der, 15, at night, • • • • 16, p. m. • • • with thunder and lightning, and at night, • • • with thunder and lightning, 19, 24, at night, • • • 25, • • 30. Coldest day, 16. Therm. 55.? Height at a Hottest days, 24, 28, 29, 30. 65.$ med. 611*. May was clear, calm, and warm, excepting the 15th and 16th days, when it blew violently from the north. Rainy days, 20, p. m. 21, p. m. Coldest day, 16. Therm. 61.? Height at a Hottest days, 25, 30, 31. 72. $ med. 68-37T. About the middle of June the northeast winds blowing fresh for some days, allayed the heat of the air, but did great damage to the fruit trees. Rainy day, 26, at noon, • • • ■ Coldest day, 18. Therm. 71. ? Height at a Hottest days, 12, 13. 80.$ med. 75§§. The first weeks of July were extremely hot and sultry, especially from the 6th to the 16th; the mer- cury in the thermometer rising daily above the 80th degree. Nor was the latter part of it much more temperate, though it blew from the north pretty briskly on the 17th and 18th, and moderately about the end of the month. Rainy days, 2, a. m. 16, at night, 17th, at night, 18, at noon, • • • • 31, at night, • • • with thunder and lightning. Coldest day, 18. Therm. 74. ? Height at a Hottest days, 14, 15, 16. 84. S med 71 s_ J ""31' On the 5th, the th. in the shade 79, exposed to the sun 96. 1748. OF THE WEATHER. 69 The excessive heat of the season continued to the 19th of August; when it intermitted for some days, the clouds threatening rain, with boisterous winds from the north, especially in the night time. On the 24th it again became sultry, and continued so to the end of the month. Rainy days, 3, a. m. 7, at night, 19, a. m. with thunder and lightning, and at night, • • • • Coldest days, Therm. 74. ? Height at a Hottest day, 15. 85.$ med. 7974T. On the 9th, the th. in the shade 77, exposed to the sun 95. 10th, 79, 96. 14th, 84, 101. 15th, 85, 100. In September, though the sky was often overcast, with signs of rain, yet the showers were neither so heavy nor so frequent as they commonly are about this time of the year: but large dews falling in the nights, and constant breezes from the north, render- ed the air temperate, as it commonly is in this month. Rainy days, 8, at night, 9, at night, with thunder and lightning, 17, at night, 18, at night, 23, at noon, • • • • and at night, • • • • 24, a. m. • • Coldest day, 25. Therm. 66. ? Height at a Hottest days, 7, 8. 80. $ med. 73^|. On the 22d the therm, in the shade 73, exposed to the sun 96. The first ten days in October were mostly fair, clear, and calm, and also the last week of the month: all the intermediate days were either wet, or windy and overcast. Rainy days, 1, at noon, • • 9, p. m. 10, p. m, • * 70 OF THE WEATHER. 1749. and at night, • • • • 11, * • • • 12, at night, • • • • 14, • • • 15, • • 19, 20, at night, • • • • 21, at night, • • 22, 23, at noon, • • • • 27, at noon, Coldest days, 12, 13. Therm. 58.? Height at a Hottest day, 7. 72. $ med. 65|f Towards the beginning and end of November the weather was temperate and serene. During the mid- dle part of the month it was frequently cloudy and cold with dry north winds. Rainy days, 8, at noon, • • • • with thunder and lightning, and at night, • • • • 11, a. m. 20, • • • • 22, 26, • • • • Coldest day, 23. Therm. 53. ? Height at a Hottest days, 1, 2, 3. 66. $ med. 58 ^. In December the wind was either southerly or westerly: hence the weather was never cold; and though some days were foggy, yet by much the greater part of this month was dry, clear, and very pleasant. Rainy days, 14, • • • at night, 21. Coldest days, 9 to 17. Therm. 5 6. ? Height at a Hottest days, 27 to 31. 60. $ med. 57|f A. D. MDCCXLIX. So mild was the weather in January that it scarce seemed to be winter. The preceding autumn having been uncommonly dry, and the showers which fell during the first three months of this year being nei- ther frequent nor plentiful, the grain in many places perished for want of rain. Rainy days, 4, a. m. 7, at noon, and at night, • • • 18, p. m. 19, at night, 20, at noon. 1^49. OF THE WEATHER. 71 Coldest days, 6, 7. Therm. 53.? Height at a Hottest days, 1, 2, 16, 17, 58.$ med. 55^, February was likewise mild and temperate, the mercury in the thermometer fluctuating between the 54th and 57th degree: a little rain fell on the first days, a heavy shower on the 12th, slighter showers on the 22d and 23d; during the rest of this month the air was clear and dry. March was fair, warm, and without rain, both to- wards the beginning and end; the thermometer standing above the 60th degree. Between the 9th and 22d day, frequent storms of rain, with some hail, intervened, which sunk the mercury to the fifty second degree. The weather during almost all April was mild, clear, and agreeable. Rainy days, 7, a. m. • • • and p. m. • • • • 10, p. m. • • • and at night, • • • Coldest days, 8, 9. Therm. 56. ? Height at a Hottest day, 30. 69.5 med. 62ff In May sudden heavy rains sometimes interrupted the serenity of the weather; and at the close of the month a strong westerly wind did much damage to the vineyards. The harvest this year was so poor and scanty (especially in the northern parts of the island, where the droughts were most excessive), that they scarcely reaped as much grain as they had sowed. Rainy days, 3, p. m. • • • • 11, at noon, • • * • 12, at noon, • • • 16, 19, 25, at night, • • • 31, at night, • • • with thunder and lightning. Coldest day, 4. Therm. 64. ? Height at a Hottest days, 24, 25. 73.$ med. 68£. 72 6F THE WEATHER. 1749. During the month of June the air was dry and ex- cessively hot, though somewhat more temperate be- tween the 14th and the 25th; frequent gales coming from the north. Rainy day, 15, p. m. Coldest day, 1. Therm. 69. ? Height at a Hottest day, 30. 79. $ med. 74j63. On the 29th the therm, in the shade 76, exposed to the sun 96. The weather has seldom been felt so extremely hot and sultry as this year in July; the quicksilver rising daily above the 80th degree of the thermometer, and never falling below the 79th, even in the night time, till the rains which fell in the latter part of the month had cooled the air. Rainy days, 25, at noon, • • • 26, p. m. • • • • Coldest days, 26, 27. Therm. 77. ? Height at a Hottest day, 20. 86.$ med. 82£. On the 3d the th. in the shade 82, exposed to the sun 102. 4th, 84, 100. 13th, 84, 104. 14th, 85, 104. In the beginning of August a general relief of all his majesty's troops in the island obliged me to em- bark for Ireland, and put an end to these observations. OF THE WEATHER. 73 A TABLE showing the greatest, least, and mean height of the mer- cury at three o'clock in the afternoon, in each month, from the year 1744 to 1749. | (1744 1745 1746 1747 1748 57 43 51^ •"31 1749 January G L M 57 43 52 57 48 «023 ^3l 59 50 55TT 58 53 57 ' 54 February G L M 61 46 55 57 45 51^ J126 62 45 55^ 60 48 55 March G L M 63 51 59 50 42 54 5 J131 63 50 54-i^ D*31 63 50 5 5-9-J0 3 1 64 52 April G L M 65 58 61^4 O130 68 54 5922 3:,30 68 56 U130 65 55 61^ U130 69 56 fi223 May G L M 74 62 «838T 70 64 68^ 75 67 71 72 61 68/7 73 64 68A June G L M 82 69 731 79 69 73J-2-'^To 80 71 76 80 71 75.21 ' °30 79 69 74-?-' *30 July G L M 80 70 7fi19 80 75 7712 ' ' 3 1 87 77 80|f 84 73 79 3-' J31 84 74 79-5-"31 86 77 82Jj August G L M 80 73 77_2_ 3 1 82 74 772J. "31 81 70 76i£ ' "3 1 84 74 80-34T 85 74 79-^-"31 September G L M 76 71 71-2- 80 69 ' .3 0 74 58 67^ 81 63 7022 80 66 7<321 October G L M 71 65 67 50 56 69 61 65^ "331 68 54 58§} 70 62 65^1 U331 72 58 UJ3 1 November G L M 65 , 50 5 8-s-°°30 62 54 01 30 67 51 60^ 66 53 5 8-3- i 1 G December L 1 lM 57 44 5»1 60 48 DO30 59 54 56 64 53 68^ 60 56 °' 3 1 1 i G 75 CHAPTER II. Of the Rise, Progress, Declension, and Succession of the Epidemical Diseases,from the year 1744 to 1749. A.D. MDCCXLIV. IN the beginning of the year few diseases appeared, except some pleurisies and tertian fevers; both which are common in Minorca, and are frequently met with in all seasons ; the first being generally the chief amongst vernal epidemics, as the other is con- stantly amongst the autumnal. During the cold weather in March many adults were affected with catarrhs, and almost all the chil- dren were seized with a smart fever, attended by a cough; which disorders did not cease till the begin- ning of summer. As the summer and autumnal weather of one year never varies much from that of another, so the same tribes of distempers return regularly with the seasons, and succeed each other in the following order. Toward the end of June the young children (who constantly suffer first by excessive heat or cold) are attacked with a vomiting, purging, and periodical fever, often of the erratic kind, without any fixed type, (a) (a) This disease among children appears to be what has re- ceived in the United States the name of the cholera infantum. The author mentions it again in two other places. It is briefly described in a late publication on the diseases of India, by Mr. Custis, surgeon of the Medea frigate. Our author's account of 76 OF THE RISE, PROGRESS, Sec. In the following month tertian fevers of vai-ious forms appear among people of all ages, and spread-. ing from one to another, by contagion, continue to increase daily till about the time of the autumnal equinox, when they rage with the utmost fury amongst persons of all ranks and constitutions, whe- ther natives or foreigners. Afterwards they gradual- ly decline; and as soon as the winter begins, their contagion being rendered inactive by the cold, few persons who have hitherto escaped are infected. Yet some primary fevers continue to January, and re- lapses are exceedingly frequent in the latter months of the year. (£) About the time when the tertians begin, the cho- lera morbus, rash, and essere, become frequent and epidemical in a less degree: but are seldom met with after September, whilst the tertians continue till winter. it accords with the same disease in our country, in making its appearance sooner than the bilious fevers (of which it is a form) in adults. (6) Our author has followed the physicians of the continent of Europe in supposing tertian or bilious fevers to be contagious. They spread only from the action of an impure atmosphere, and never extend beyond its influence. If a whole family succumb under it, after it has affected one of them, it must be ascribed to the same air, and to the fatigue or distress of nursing the person first attacked, affecting the rest of the family. The ex- tinction of this fever by cold, which our author mentions, proves it to be an atmospherical "disease, for cold cannot penetrate houses to destroy the contagion. On the contrary, the shutting of doors and windows which follows the action of the cold, ought rather to accumulate and increase it. The small pox, which is a contagious disease, is not checked by cold weather. OF EPIDEMICAL DISEASES. 77 Diarrhoeas, dysenteries, and tenesmus, likewise make their appearance as epidemicks, in summer and autumn: but some years they occur so seldom, as scarce to deserve that name; whilst in others they are almost as numerous as the tertians themselves. There seems likewise to be a near alliance amongst all the diseases above mentioned. Those who have the rash, or essere, to a great degree, are very liable to tertian fevers; on the other hand, in the paroxysms of tertians these cutaneous eruptions are apt to break out. The cholera morbus sometimes hath its regular pe- riods, like a tertian, as the paroxysms of tertians are frequently attended with a cholera. Sometimes a tertian is changed into a dysentery; or a dysentery becomes a tertian; and when one of these diseases is suppressed, the other often ensues; nor is it uncom- mon for dysenteric fevers to put on the form of tertians; and for the fits of tertians to be regularly accompanied by gripes and stools, (c) It is remarkable that both dysenteries and tertians, without any manifest cause, are sometimes more uni- versal and severe in one part of the island in one year than another; and often seem, as it were, to attack particular families with uncommon severity; whilst others in the same place, the same circumstances and way of life, escape. Those, however, who live in low valleys, or near stagnating corrupted waters, are commonly the greatest sufferers. To me it appears probable that all the summer and autumnal diseases are the consequence of nature's (c) We see in the whole of this paragraph a striking proof of the unity of the autumnal disease, however diversified it ma\ he in its seats or symptoms. G 2 78 OF THE RISE, PROGRESS, See. attempting to free the body from noxious humours, either by throwing them upon the skin, or by con- veying them through the liver and other organs of secretion, which open into the intestines. (*/) And if, with the ancients, we allow distempered bile to be the cause of tertian fevers, it will perhaps be easier to account for their more obvious appearances, than by supposing them to arise from a lentor in the smaller arteries, according to the modern theory: but this is transiently offered as a conjecture; to re- cord facts without framing any hypothesis, being my principal design. In July 1744 tertian fevers were numerous; but during the two ensuing months they were neither so universal nor so malignant as they commonly are at this time of the year: yet obstinate relapses were frequently met with till January. A little before the equinox dysenteries of a bad kind began to appear; and being propagated by con- tagion, (e) like the tertian fevers, they soon increased to such a degree, that it was doubtful which of the two distempers was more universal. This year, in the space of three months, I had more patients with bloody fluxes, than in all the former part of my life; and as no manifest quality in the air, nor variation in the weather, seemed capable of producing them, it is probable that their uncommon frequency and singular severity were chiefly owing to the sour da- (uibus tertio die subsistit accessio et quarto ingravescit malum. Yet from the following passage in Torti I imagine that experienced physician must have met with accidents of the same kind. Suspecta itaque ab exordio erit, ne in continuum degeneret, intermittens, qua cum pauco aut nulla rigore solet invader e, sed pot i us cum sensu color is. Item qua primo die leviusculam (dum modo tatnen vere febrilemj infert accessionem; altero vero die (~non altera pcriodojfortiorcm, et sic progrediendo modum servat graviorem per dies pares, loquendo per modum exeTnpli, de tcrtiana duplici ab ortu- S>uod si eadem sic orta in simplicem statim mutetur, etsi hoc laud'abile sit, tatnen non desinit esse suspectum, si primam accessionem validam, debilis, ut supra, immediate prtecessit: potest enim facile ille typus mutari qui ordine inverso potuit incipere. Therap. Special. I. iii. c. . \ The English in Minorca are more liable than the natives to become yellow in these fevers. 102 OF TERTIAN FEVERS. perceptible about the patient's bed; if in the time of the fit he continues cold and chilly, without being able to recover heat; or if he becomes extremely hot, speechless, and stupid; has frequent sighs, groans, or hiccoughs; and lies constantly on his back, with a ghastly countenance, his eyes half shut, his mouth open, his belly swelled to an enormous size, with an obstinate costiveness, or an involuntary dis- charge of the excrements: which formidable symp- toms, as they seldom appear before the third revo- lution of the disease, so they frequently come on, both in double and simple intermittents, during the fourth, fifth or sixth period, even where the smallest danger was not foreseen. But at whatever time the greater part of them concurs, they afford a melan- choly prognostic; for notwithstanding they sometimes go entirely off with the paroxysm, and the patient seems to be left in a fair way of recovery, yet most commonly they return in the next period with double violence, and terminate in sudden death. Agreeably to this Hippocrates tells us, " In the summer, inter- mittent fevers and the cholera morbus prevail; and as they sometimes degenerate into malignant acute diseases, we should be upon our guard; the fifth, seventh, and ninth days point out the danger; but we must be cautious to the fourteenth." (De Morb. Popular. 1. vii.) For the fifth day, if the bad symp- toms just now mentioned, appear on it, will indicate death on the seventh. In the same manner the se- venth will indicate the ninth, and the ninth the eleventh to be fatal, provided the paroxysms are aggravated on the odd days; for if they are most vehement on the even days, one of these days will OF TERTIAN FEVERS. 103 prove indicatory as well as critical. Hence we find Galen* lays down as a general rule, that those who grow remarkably worse on the fourth day, die on the sixth; and with equal justice he might have said the same thing of the sixth day, with regard to the eighth, and of the eighth, with respect to the tenth. Nor is there only a possibility, in many cases, of foretelling the day, but likewise the hour on which the patient will expire; for that stage of the parox- ysm, which he usually got over with most difficulty, will most probably in the end prove fatal, as Galen has also remarked. (De Crisib. 1. iii. c. x.) I have seen some expire in what may be called the first stage of the paroxysm; the skin being chilled and wet with cold sweats, their pulse small and irregular, and their senses entire to the very last. But the greatest numbers are hurried off in the height of the hot fit, stupified, senseless, the breathing short and laborious, and the skin covered with a burning fiery sweat. In the meantime it is to be remembered, that as in all acute diseases, so particularly in those fraudu- lent deceitful fevers, the presages either of death or recovery are not always certain and infallible; it frequently happening that those who have laid in the paroxysm for hours together, with few or no signs of life, have at length recovered, as it were, from, the jaws of death, and asked for some uncommon sort of food, to the great surprise of every body about them; on the other hand, the fit anticipating sometimes brings on death before the time it was indicated. * Etenim qui in quarto ad pejorem statum recidunt, plerunv- que sexto moriuntur. De Dieb. Decret. 1. i. cap. iv. 104 OF TERTIAN FEVERS. I have examined the bodies of near a hundred persons, who perished in those fevers, and constantly found one or other of the adipose parts in the lower belly, (the cawl, mesentery, colon, &c.) of a dark black complexion, or totally corrupted; the vesica fellea full and turgid, and the stomach and intestines overflowing with bilious matter; the spleen large, sometimes weighing four or five pounds, and so ex- cessively soft and rotten, that it had more the ap- pearance of congealed blood wrapt up in a membrane, than of an organical part. In the cavity of the head and breast nothing extraordinary was met with, ex- cepting yellow serum, when the skin was tinged with the same colour. Some observations relating to malignant tertians are handed down to us by Coelius Aurelianus, which, for the reader's information, I shall transcribe at the bottom of the page;* and whoever is acquaint- * Haec passio (nempe apprehensio sive oppressio) lethargic ?imilis est. Hippocrates et Diodes ct?uvixv appellavit, Praxago- ras Ka/ta.Ta$mi, Antigenes avxvfixv, Asclepiades Catalepsin__ Diocles ait (1) de/ectivasfebres tutas et innoxias esse frequentius quam sunt continue, quamquam et in his periclitentur, qui in accessionibus apprehensi conticescunt, vel raptu quodam alterno per membra tentantur, cum supra dictis: quod sa;pe, inquit, est accidens pueris. Item Praxagoras ait esse quasdam febres ex anno duodecimo usque ad annum xvi aut xvu, qu) The practice of the British physicians in abstracting animal broths from patients in fevers of great morbid excitement should be imitated by the physicians oi' the United States. In low chronic fevers, not only those broths, but animal food may be taken with safety and advantage. * Pomaceos fructus, exquisitis tertianis liberaliter exhibere convenit, nempe uvam dulcem, Persica cocta, et non cocta, peponumque medullam; praesertim autem si etiam aegriMti vex- entur. Ego sane novi me frequenter aegros, ne amplius acces- sione febris infestarenlur, impedivisse, cum pepones probe refrigeratos, hora ante incursum morbi, assumere jussissem, et rursus aquam temperatam copiosam, et quantam potuerint peponi superbibendam praecepissem. Secutus itaque est, non multo post aquam epotam, aliquibus sane sudor, aliis copiosa bilis per alvum. Offendi autem ego plerosque Romae medicos, qui ne nomen quidem peponum tanquam bilem procreantium proferre audebant. Quum itaque ego cuidam aliquando, et si- tienti vehementer et cestu flagranti defatigatoque injunxissem, ut peponem assumeret, quidam praesens medicus exclamavit, homo, cur aegrum inagls vis occidere? Annon didicisti quodpe- pon bilem producat? Lege Galenum de alimentis, ubi dieat ma- nifeste peponem comestum cholericos efficere. Laboravi igitur ego, non parum, ut iis persuaderem, qui intellectu assequi po- terant, Galenum non dicere hie ipsos pepones bilem creare, sed choleram efficere. Proinde tertiana febre detentis, cum fiducia dare debent. Quomodo enim ea, quae refrigerant et huniectant, bilem creare possint, non video. Lib. xii. c. vi. OF TERTIAN FEVERS. H3 of grapes and peaches in tertians, and boasts of the many cures which he had performed to the great surprise of his contemporaries, by giving water me- lons, and large draughts of cool water an hour before the fit. Avicenna recommends pomegranates and ripe plumbs, but above all the water melons.* And Galen himself, though he was unreasonably preju- diced against the summer fruits (a surfeit of which threw him into a fit of sickness when a boy), yet in the present case he allows the use of such of them as are not difficult to be digested. (Ad Glauc. 1. i. c. ix.) And indeed in several other places of his works he is obliged to contradict his own opinion of their being unwholesome nourishment; particularly where he tells us, " that those who are set to watch the vineyards, and live for two months on grapes, figs, and bread, become fat and lusty." (De Alim. Facult. 1. ii. c. ii. et ix.) Which observation is an- nually confirmed in Minorca, it being remarkable that the persons appointed for the same purpose there commonly continue in good health, though in that season tertians usually rage with the greatest violence, (jf) * In Opere Venet. de Febr. c. xxxviii. p. 31. (q) The efficacy of a vegetable diet in preventing autumnal fevers will depend much upon their grade. Where they are at- tended with highly inflammatory or malignant symptoms, it is an almost certain preventive of them. The Bramins in India, who live wholly upon vegetables, enjoy good health in the neighbourhood of garrisons and factories of Europeans, who sicken and die from a predisposition to the fevers of the country, induced by a diet of animal food. Vegetable aliment induces a predisposition to fevers of weak morbid action. They are ob- viated by a cordial diet, and drinks. ' K 2 114 OF TERTIAN FEVERS. Before I have done with the diet of the sick, it may be noted that, although in the beginning of those fevers they commonly loathe every thing, ex- cept thin, cooling, acescent liquors, yet after some days wine becomes less disagreeable, and towards the decline of the disease, a prudent use of it, mixed with water, or made into whey, is often absolutely necessary to keep up the failing strength, and prevent weakness, the worst of all distempers. With regard to bleeding, it has been warmly de- bated among both ancient and modern authors, whether it ought or ought not to be used in tertian fevers. Much has been written on both sides; but the question appears to me too general to admit of a po- sitive answer. Celsus has justly observed that "Me- dicines differ according to the nature of the climate; one kind being necessary in Rome, another in Egypt, and a third in France." (De Med. Praefat.) And since we daily meet with a remarkable diversity of symptoms among fevers of the tertian tribe, even in the same climate, at the same season of the year, it cannot surely be surprising that any one remedy is not equally beneficial in all cases, and at all times. For my own part, when I was called early enough, in the beginning of those fevers I used to take awav some blood from people of all ages, unless there was a strong contraindication; namely, from robust adults ten or twelve ounces; from others a smaller quantity in proportion to their strength and years. And farther, if a violent headach, and obstinate de- lirium, and great heat or pains of the bowels were urgent, within a day or two I repeated the bleeding. By which seasonable evacuation the vchemency of OF TERTIAN FEVERS. H5 the paroxysms is somewhat' diminished; the apy- rexies become more complete; the operation of eme- tics and cathartics is rendered safer and more suc- cessful; and the terrible symptoms, which often make their appearance about the height of the dis- temper, such as raving sopor, difficulty of breathing, inflammations of the abdominal viscera, &c. are either prevented or mitigated, (r) But if before I was called the fever had already continued some time, and the mass of blood appear- ed to be too much melted down, or inclinable to a putrid dissolution, which is often the case, during the extreme hot weather, about the fourth period of the distemper, and is readily known by the great alteration of the patient's looks and his sudden loss of strength; or if the first paroxysms of the disease were attended with profuse evacuations, whether by vomiting, purging, sweating, or a hemorrhage from the nose: in all these circumstances I either omitted the bleeding entirely, or took away a very small quantity, though some importunate symptoms might seem to require a much larger evacuation. But when bleeding is allowed to be necessary, it is asked at what particular time of the periodical revo- lution it ought to be performed? The ancients* be- lieved that " to open a vein in the height of the fever, was to destroy the patient;" and therefore they order you to wait for the intermission, or the hour in which (r) This practice is judicious, and is sanctioned by similar success attending it in the United States. * Si vehemens febris urget, in ipso impetu ejus sanguinem mittere hominem jugulareest; expectanda ergo intermissio, &c Cel.l. ii. c x. 116 OF TERTIAN FEVERS. the symptoms are generally most moderate. But the experience of the present age has taught us that this operation is safe enough, at any time of the peri- od, unless while the cold fit lasts, or is soon expect- ed; or while the skin is covered with critical sweats. (s) Of late years, encouraged by the example of some practitioners of reputation,* I commonly opened a vein in the beginning of the hot fit; by which means the sick were immediately relieved; the immoderate heat of the body (which is often productive of fatal effects) was diminished; and the critical sweats were brought on sooner, and in greater abundance. But when that time of the paroxysm was passed before my being called, I bled in the evening, when it abated or went off, that I might be at liberty next day to make use of the remission or intermission, which commonly hap- pens in the morning, to evacuate the first passages. For, the disagreeable taste in the mouth, loathing of food, giddiness, pain in the forehead and loins, and other constant attendants of tertian fevers, make it evident, that the stomach and intestines are over- loaded with noxious humours, and particularly with corrupted bile; from which if they be not early dis- charged, very threatening symptoms will be apt to ensue about this state of the disease; such as violent vomiting, redoubling or continuation of the parox- ysms, ravings, restlessness, pain, inflammation, gan- U) Bleeding is certainly safe during that coldness of the body which takes place in violent fevers. It generally removes it, and Dr. Sydenham has taught us the safety and advantage of bleeding during the sweating stage of those fevers where the sweats do not afford relief. * Astruc on Fevers, p. 71. Gourraigne de Febribus. OF TERTIAN FEVERS. 117 grene of the abdominal bowels, and lastly, sudden death. Wherefore it is not only necessary to wash the stomach with warm water or weak broth in the beginning of the fits, when indicated by an inclina- tion to vomit, and to keep the belly constantly open with clysters; but likewise to empty the first pas- sages by more powerful means at the first conve- nient interval. It is a controverted point whether it is best to discharge those noxious humours by vomit or stool. At first view vomits seem to be most eligible, as they quickly empty the superior part of the alimen- tary tube, which appears to be the principal seat of the morbific matter. But it must be considered that whatever irritates much, and produces violent com- motions, ought to be avoided in the present case. Cave ne inducas effervescentiam biliosorum, is a cau- tion given by Avicenna; and the Spaniards no more than the Italians, if their physicians may be credit- ed, cannot well bear rough medicines of any kind. (Vid. Bagliv. lib. i. c. xv. § v.) Besides, the inflam- mations of the bowels, too frequently accompanying tertians, are exasperated beyond expression by the strong contraction of the diaphragm and abdominal muscles in this operation: and if the spleen or liver is disposed to become putrid (which is no uncom- mon case in those fevers), it is needless to point out the dangerous consequences that may result from the repeated efforts of vomiting. For which reasons mild purgatives, though less powerful remedies, are th<- safest, and therefore to be preferred in the gene- rality of cases. Those which I have found most be- neficial are senna, manna, cremor tartari; but above 118 OF TERTIAN FEVERS. all the sal catharticum amarUm, which neither gripes nor disturbs the body, and seldom fails of having the desired effect in a few hours, a circumstance of great moment where the intervals are short. But if vomits are to be used, they should be given in the beginning of the disease, before repeated pa- roxysms have brought on inflammations, or too much dissolved the texture of the blood; taking care that the operation does not interfere with the fit, lest some sudden mischief should arise from the united shock of the remedy and the disease. (/) When I first became acquainted with those dis- eases, the uncommon violence of their symptoms induced me to lay the principal stress of the cure on evacuations; and to have recourse to frequent bleed- ing upon account of the inflammations of the viscera: endeavouring at the same time by repeated cathar- tics to discharge the corrupted humours from the intestines: but when experience had convinced me that the bark was both a safe and effectual remedy in those circumstances, I then plainly perceived that such profuse evacuations were unnecessary, if not prejudicial; and of late years, as I seldom omitted to bleed and purge once or twice, I rarely repeated either operation oftener. In semitertians and remittents, which approach to the nature of continual fevers, I give a cathartic ' (0 The remarks of our author upon the comparative effects of vomits and purges in these fevers are correct; nor do his ob- jections to the former militate against the propriety of the practice of Dr. Sydenham, who gave them in the advanced stage of fevers, for it was in fevers in which there was no dispo- sition to inflammation or congestions in the abdominal viscera. OF TERTIAN FEVERS. 119 early in the morning of that day on which the symp- toms are most moderate; hastening the operation with clysters (if occasion require), so that it may be finished before the middle of the day, about which time the patient commonly grows worse, (u) In true simple and double tertians there is generally an in- terval every morning, in which the purgative may be administered, but that which succeeds the worst fit is the most proper, as it is more calm, and conti- nues longer than the other. Another inducement to purge in the beginning of tertians is, that these fevers are sometimes accom- panied with worms in the first passages. Proper evacuations being premised, if possible, within the first four or five days of the distemper, I carefully examine the condition of the patient dur- ing the third revolution, and determine accordingly in what manner it will be necessary to proceed. If the paroxysms of that revolution be neither longer, nor attended with more threatening symptoms, than those of the second; if the patient preserves his strength, bears his illness easily, and signs of con- coction appear in the urine; I frequently trust the whole business to nature, which commonly termi- nates the fever about the fourth or fifth revolution, and, for the most part, with an increase of some of the natural evacuations; so that sweats, cloudy or thick urine, and bilious stools often supervene, and (u) This practice of giving purges on the days of remission in autumnal fevers is judicious, and should be adopted by all physicians. They operate soonest and most freely on those days, and render the succeeding fits more easy. 120 OF TERTIAN FEVERS. sometimes a spontaneous efflux of spittle, or a co- pious expectoration of pituitous matter, (w) But if the paroxysm on the fifth day be evidently the longest and most severe that has happened; if it be attended with any doubtful or dangerous symp- tom; if the sick become giddy, feeble, and languid; in these cases, without delay, I have recourse to the bark; and the same evening, as soon as the sweats have procured a remission, I order two scruples or a drachm of it in powder to be given every two or three hours, or every hour and a half, so that five or six drachms may be taken before next day at noon, with as little interruption to their sleep as may be; and the assistants are strictly enjoined to comply punctually with thtse directions, lest if this interval escape, we should not afterwards have a favourable opportunity of giving a sufficient quantity of the me- dicine, as the fits about this period of the disease are wont to become double, subintrant, or continual. Yet it is not always in our power to put an im- mediate stop to the fever by this means: on the con- trary, do what we can, it will often proceed in its career, and, in spite of all our attempts, run obsti- nately on to the seventh or ninth day. But the great advantage which accrues from the early use of the bark is, that it invigorates the powers of the body, prevents or removes the dangerous symptoms, and in tertians, which of their own accord would conti- (iu) The bilious, or, as it was commonly called, the " break bone" fever, which prevailed in Philadelphia in the year 1780, was attended with that constant hawking and spitting in many people, which is called " screatus" by Latin writers. All who had it, recovered speedily. OF TERTIAN FEVERS. 121 nue to the end of the second week or longer, it brings on a crisis sooner, and with much less dis- turbance. In short, to use the expression of one of the greatest promoters of medical knowledge in this age,* " it proves an excellent assistant to nature in what the ancients called, the concoction and matura- tion of the morbid matter;" and (I must add) in the expulsion of it likewise, sensibly or insensibly, by the most convenient outlets. For so far is it from suppressing any beneficial discharge, as some have asserted, that we daily observe a laudable separation in the urine, warm, profuse, universal sweats, plen- tiful bilious stools, and sometimes the haemorrhoids and menses coming on after it has been used; though it effectually restrains the colliquative night sweats, to which persons weakened by tedious in- termittents are incident. Having given the bark, in the manner directed, on the fifth day of the fever, if a paroxysm comes on on the sixth, and declines the same evening, I order a few more doses to be taken, with a view to pre- vent, if possible, or at least to mitigate, the fit ex- pected on the seventh. Yet it sometimes happens that the fit of the sixth day unites with that of the seventh, no remission intervening, so that the heat, restlessness, raving, and other complaints being greatly augmented, the case seems to be much more desperate than ever. But those commotions which follow upon the use of the bark in this stage of the fever, are more dangerous in appearance than reali- * Monro on the Use of the Bark in Smallpox and Gangrenes, Med. Essays, Vol. v. Art. x. L 122 OF TERTIAN FEVERS. ty; and so far from being alarmed at the sight of them, I commonly give expectation that a remission with profuse evacuations will happen the next even- ing; at the same time giving positive assurances that if the patient takes as much bark in that inter- val, as he did in the former, he will either have no more fits, or moderate ones, which will quickly yield to the same sort of management. By this method, when assistance is timely called, the most formidable kinds of intermitting and re- mitting tertians, whether appearing in their own proper colours, or personating other distempers, may be certainly and speedily brought to a happy con- clusion about the end of the first week or beginning of the second. But if the fever has been neglected in the begin- ning, and you are not called till about the third or fourth period; when by the use of spirituous liquors, strong vomits, or violent exercise, the bowels are inflamed; or for Avant of seasonable evacuations, the - first passages are overcharged with corrupted gall, and other putrid matter; the fits tedious and subin- trant; or perhaps attended with a stupor, syncope, cholera morbus, cold sweats, and great weakness. These, indeed, are terrible cases, yet such as too frequently happen, and involve the physician in the greatest perplexity. So many indications and contra- indications present themselves at the same time, that by obviating one symptom you hazard the increase of another:* nor, under such circumstances, is it * Saepissime ad aegrotos vocatus, tantam tamque confusam, mirabar, symptomatum turbam, ut purgatio ne, an venaesectio' vel neutra, imprimis foret eligenda, decernere anceps et summi OF TERTIAN FEVERS. * 123 easy to lay down rules for managing the sick: all that can be with safety advised is, to palliate the most pressing complaints in the manner hereafter proposed; in the meantime carefully watching the evening, the night, and the early part of the mor- ning, for a remission; and the moment it offers, to fly to the bark as to, the only remedy which can avert the impending danger. If the patient seems strong enough to bear purg- ing, I divide an ounce or six drachms of sal cathar- ticum amarum, and half an ounce of bark, into four equal parts, and order one to be taken every two hours: the effect of this is, that the next fit is miti- gated, and an intermission commonly ensues, in which the bark without the purgative must be re- peated to finish the cure.* But if the patient is so excessively feeble, that there is a manifest risk of his dying in the next pe- riod of the fever, instead of the sal catharticum, I give the bark with cordials (among which wine is by much the best), and endeavour to have six or seven drachms of it taken in the space of ten or ponderis negotium esset. Nee doctorum, ut gravissimorum, consilia poterant in illis casibus suffragari, quin in alterutra operatione tentanda adhuc extaret ambiguitas. Guidet.de Tertian. Autumn, apud Bianch. Hist. Hepat. par. iii. p. 287. * Si tamen vacuatione opus sit, et ab urgente febre tempus ad exhibendum catharticum denegetur, post V. S. cortex Pe- ruvianus, cum purgante medicamento idoneo conjunctus, statim exhibeatur. Geoffr. Mat. Med. vol. ii. p. 188. Tuto igitur in perniciosis his frebibus febrifugum quocunque tempore potissimum purgantibus immixtum propinetur. Bianch. Hist. Hep. par. iii. p. 287 124 OV TERTIAN FEVERS. twelve hours; having found by experience that the paroxysms, if a smaller quantity is given, too fre- quently come on earlier than usual, and make all attempts to preserve life unsuccessful.* When the sick are out of danger, and have re- covered a sufficient degree of strength, bleeding and purging may safely be directed, notwithstanding the use of the bark, if these evacuations are indicated; and so far is opening the belly occasionally from bringing on a relapse, that those who have had the best opportunities of making the trial,f have found it to be the most probable means of preventing a re- turn of the fever, (x) This is the method of using the cortex, into which I at length fell, after trying a great variety of others. * For which reason, in such deplorable cases, Torti orders half an ounce or six drachms of bark to be swallowed at once ; which he affirms is much more powerful than the same quanti- ty divided into several doses. Vid. Therap. Spec. 1. iii. c. iii. f Qui dictitant febrem per corticem Peruvianum deletam, si postea cathartica propinentur, revocari, hosce toto quidem coelo hallucinari, assidua nos docuit experientia, qua aegros post ex- hibitum corticem a febre liberos, per subrogata purgantia tutius a relapsu praecaveri recognovimus. Blanch. Hist. Hep. par. iii. p. 283. Mixtionem rhabarbari cum china ipse ego apud Italos, xx circiter abhinc annis, primus faustam prosperamque hisce in casibus expertus fui, felicemque exitum, cum aliis, per episto- las communicavi. Lancis. lib. ii. epid. iv. c. vi. Cortex cum rhabarbaro, anno 1710, non ea felicitate stimula- bat alvum, qua anno 1708 et 1709, et propterea opus erat illiu* remedii usum grandioribus catharticis interrumpere. Lane. epid. iv. c. viii. (*) This is true with respect to the acute fevers described by our author, but in autumnal fevers of weak morbid action a purge often brings back the disease. OF TERTIAN FEVERS. 1^5 Sometimes, indeed, extreme weakness, or some for- midable symptom, obliged me to have recourse to it in the second period of the fever; but I never chose to give it before the third, nor to delay it after the fourth, in all cases of any consequence, provided there was a proper interval for its administration; and with its assistance, if the patients were not al- together exhausted, I had the pleasure of seeing them happily rescued from tertians of the most ma- lignant kind, such as the lipyria, assodes, febris syncopalis, &c. What the poet says on a different occasion being literally true in the present case. Hi motus, et haec cerlamina tanta Pulveris exigui jactu compressa quiescunt. Virg. Georg. iv. And the more experience I had of the bark, the more I was convinced of both its innocency and efficacy; so that I heartily wish I had always given it with as much freedom as I did during the last seven years of my stay in Minorca: but the prejudices against this medicine, which I had early imbibed from some of the most approved authors, made me for a long time use it with too much diffidence.* * Major medentium pars apud nostrates, ut vulgi calumniis, et assiduis xgrorum querimoniis se subducerent, in hac tem- pestate ad Peruvianum corticem confugere: Atparum prospere; nam in perniciosos scopulos aegrotantes suos persaepe deduxere. Usu febrifugi, per aliquot dies, equidem latebat sub cinere do- loso ignis, verum postliminio violenter recrudescebat Ramaz. Cons. epid. 1690. Adverte quaeso, mi nepos, et diligenter observa febres inter- mittentes post epotam chinam nunquam ad veram et perf'ectam apyrexiam pertingere, qualis contingit, quando natura sponte per sudorem aut alias vias accessionem discutit, &c. &.c. &c. Ramaz. de Usu & Abusu China:. L2 126 OF TERTIAN FEVERS. In the first place, I suspected that the relapses, so frequent from July to January, were in some mea- sure owing to the general use of the bark: and as I observed, that the greatest number of tertians went away of their own accord in a fortnight's time, I thought it Avould be more advantageous to the pa- tient to suffer a few paroxysms, and, when no im- mediate danger appeared, to wait the spontaneous termination of the fever, than to hazard a return by having it prematurely suppressed: but afterwards, by comparing a number of cases which had termi- nated of their own accord, with others wherein the bark had been given, I evidently saw that those were most liable to a relapse whose strength had been most impaired by the primary fever, whether they had been cured by art or nature; so that a delay in giving the bark seems frequently to have produced the effects ascribed to its having been used too early. Besides, while I was waiting for the spontaneous crises, even in cases where the mildness of the fits, and the length of the intermissions, afforded the most flattering hopes of a favourable issue, I now and then had the mortification to find my patient unexpectedly seized with a violent malignant pa- roxysm, attended by a stupor, speechlessness, and apoplectic symptoms, which seldom indeed proved fatal immediately, but were often succeeded by such insuperable weakness, that the bark could not be administered, or was given unsuccessfully, so that he died in the next period of the fever. The first two or three accidents of this kind I was willing to im- pute to some concealed irregularity in the use of the nonnaturals; but I have since been taught by too OF TERTIAN FEVERS. 127 many instances, that during the months of July, August, and September, it is very common for those fallacious fevers about the end of their second week, suddenly to change from the mildest to the most formidable aspect; and consequently that it is dan- gerous to permit their continuing so long, (j/) The repetition of such accidents first induced me to think of writing on this subject, considering it as an in- dispensable duty to point out the danger of such omissions, to practitioners of less experience, in or- der to prevent them from being misled by the plau- sible theory of some authors, and the positive asser- tions of others, though delivered in so dogmatical a manner, as if they were wholly the result of careful observation. So that I must inculcate it as a rule of the utmost importance in the cure of those epi- demical tertians, never to wait longer than the end of the first week, or the beginning of the second, for their spontaneous terminations, but without farther delay to apply to the bark. Secondly, Before I learned, by observing the course of those fevers when left to themselves, that it is customary for them, in their progress, to vary their type, and increase in violence to the third, fourth, or fifth periods, I suspected that the hasty administration of the bark not only produced the inflammation of the bowels, delirium, and other bad (y) The yellow fever in Philadelphia in 1803 came on in like manner in the form of a mild remittent in its first stage, and went off with all the symptoms of the worst grade of that dis- ease. We are told in Sir George Staunton's Account of the Em- bassy to China, that the malignant and mortal fevers of Batavia came on in the form of a tertian. 128 OF TERTIAN FEVERS. symptoms, which supervene about the height of the disease, but likewise occasioned the paroxysm to double, or perhaps continue without remission;* whereas the fact is, that many tertians which inter- mit during the first week, are very apt of their own accord to become continual fevers in the second, and extend to the 17th or 21st day, or farther, be- fore an intermission is again perceptible; but if any interval, however obscure, appears about the fifth or seventh day, and you can give them five or six drachms of bark as above directed, you will proba- * Chinam chinae dare impuro corpore, id est in principiis morborum, nullis precedentibus signis coctionis, et corpore non purgato, piaculum est in aere Romano; methodus damnabilis ac perniciosa. Dicunt multi dandum esse, ut impetus sympto- matum tunc furentium coerceatur ac refraenetur; ut inde aeger, symptomatum sopita vi, diutius possit morbo resistere. At si tu loco fraenandorum symptomatum, parvos humores per chinam chinae in aliquo viscere figas, ac concludas, et ita internam pa- rias inflammationem, ut frequentissime observavi, nonne tu cul- pandus eris? Nonne tu reus necis lege aquilia puniendus? Fe- bricitantes meos euro per leges coctionis et crisium—et raro cum recidiva: quam recidivam singulis momentis ab usu chinae chinae expectato. Bagl. de Fib. Mot. Spec. c. xiii. Pariter rubris existentibus urinis, et supra modum tinctis, cave cane pejus et angue, ne chinam chinae praescribas, sive sint acutae sive sint intermittentes febres; nam acutae, facta interna inflammatione, statim praecipitabunt in deterius; intermittentes vero statim fient continue, graves, periculosae; quare si in aliis morbis, certe quando i&ti conjunctam habent uiinam nimis ru- bram, patiens, longa, prudensque humorum coctio, semper expectanda; si secus feceris, vel mortem vel longos et incura- biles morbos expectato. Romae scribimus in aere Romano (in the noxious air of Rome)—sancte fateor, fere centies hujus- modi veritatem expertus sum Romae in aegrotantibus, et sxpe cum magno animi maerore, quando medicos in contrariam ire sententiam observabam. Bagl. Prax. Med. p. 71, &c. OF TERTIAN FEVERS. 129 bly obtain a more perfect remission in the next pe- riod; during which the like quantity must be given; and thus by repeating the remedy as opportunity offers, the disease may be brought to an end, about the ninth, eleventh, or thirteenth day. Nor ate we to hesitate in giving the bark, upon account of the crudity and redness of the urine, which I have fre- quently observed to become paler, turn cloudy, or let fall a sediment, by the use of this medicine. Thirdly, I was a long time in doubt, whether the bark might be given without prejudice, while the first passages were full of vitious humours, and the bowels were inflamed, or affected with inveterate obstructions;* but I have now good reason for as- serting, that in these very cases this medicine is of the greatest use; as it averts sudden death, and gains us time to join with it other means towards * Vid. Boerhaav. Aphor. 767. Nonnulli in his casibus (nempe tritaeophyis, hemitritaeis et aliis malignis tertianis) solent more solito cninam chinx prae- scribere; quo autem cum successu pluribus in locis hujus ope- ns animadverti. Nam hoc remedinm impuro corpori dare, saepe in aegroti perniciem vertitur; potissimum in maximo apparatu hu- morum in mesenterio. Bagl. Prax. Med. p 58. Romae scribo et in aere Romano: et ideo garriant quicquid velint chinae chinx fautores : aliis forsan in urbibus egregium est remedium, hie noxium experior. Bagl. ibid. Si chinam dederis (ut fataliter plurimi faciunt), ventre adhuc humoribus onusto, tria expectato, aut inflammationem, aut len- tam ac diuturnam febrem, aut mortem. Observa bene, et si falsa dixero, me redarguas. Romae scribo et in aere Romano. Bagl. de Fib. Motr. c. xiii. In semitertiana (inquit Hoffmannus) omittantur pulveres ad- stringentes nee non cortex chinx, &c Med. Rat. torn. 4. § i. c. v. 130 OF TERTIAN FEVERS. completing a cure. For the quantity of acrimonious contents in the primse vise is the effect of the altera- tion produced in the circulating fluids by the fever; and the longer this continues the more impurities will be accumulated, till at last they bring on a vio- lent cholera morbus; or perhaps make their way through the lacteals into the habit, and there occasion very fatal effects; all which might have been prevent- ed by the use of the bark, which removes the cause of those impurities by putting a stop to the fever; and by corroborating the solids, enables them to throw off the excrementitious fluids by the proper emunctories. (2) Inflammations of the abdominal viscera are like- wise natural effects of tertian fevers; for we find that they often come on by litde and little, and increase with every paroxysm, till at last they end in a gan- grene: whereas the cortex, by bringing the fever to a speedy conclusion, impedes the farther progress of the inflammation; so that it afterwards goes off gradually of its own accord, as I have had occasion to observe in a multitude of instances where acute- fixed pains, tension, and other symptoms, made the nature of the disease too plain to be doubted of. When the bowels are obstructed, we are told that the fever should be permitted to continue, in order to remove the obstruction, (Vanswiet. in Aph. Boer- haav. 767.); and this in many cases may be ad- (z) There are cases in which so great a prostration of strength takes place in the fevers which our author has described, that even a single evacuation from the bowels has induced death. Here bark and other stimulants are the only remedies that are calculated to do service. OF TERTIAN FEVERS. 131 visable: but at the same time it is well known, that if the obstructing matter be suddenly dissolved and pushed into the blood, it is capable of occasioning the most terrible effects. (Aph. Boerhaav. 1104.) And therefore I have commonly found it expedient, in persons troubled with hard overgrown livers and spleens, to prevent the repetition of long, severe, burning paroxysms, lest worse consequences should ensue. After the sick recovered their strength, I endeavoured to reduce the swellings of the belly, by the use of saponaceous gum pills, washed down with an infusion of juniper berries. When there is an icteritious colour in the eyes, we are likewise told that the cortex should not be administered;* though in my opinion it is for the most part dangerous to delay it, after the first ap- pearance of that symptom; which is often succeeded by a yellowness of the whole body, arising in this as Well as in other malignant fevers from a total cor- ruption, or gangrenous disposition of the mass of blood, and is too frequently the harbinger of death. (See Warren on the Malignant Fever of Barbadoes, p. xii.) Upon the whole, I am convinced that the unhappy metastases, which some have observed to follow the use of the bark, are exceedingly rare, and ought rather to be ascribed to other causes than to this medicine. (Med. Essays, vol. iv. art. xxiv.) And I will venture to affirm, that more bad consequences ensue from giving it too late than too soon; pros- tration of strength, sudden death, or the most ob- * Vanswiet. ubi supra, & Huxham on Fevers. 132 OF TERTIAN FEVERS. stinate chronic diseases, if the sick recover, being the usual effects of delay: whereas the worst that commonly happens from the too early use of it is, that it does not at once restrain the paroxysms, like a charm, without any sensible evacuation, as it fre- quently does, when given after the fever has arrived naturally to its height, and begins to decline of its own accord. Having delivered the general method of treating tertians, it is needless to say much abovit their symp- toms, as they commonly disappear with the fever itself, and seldom require a separate cure. Never- theless, it will not be amiss to take notice of a few, which I have found the most troublesome. In the first stage of the paroxysms acute pains in the back and limbs, with and without rigors or chilness, frequently happen; and I have sometimes known them so intolerable, and accompanied with such inexpressible anxiety, that persons of the sound- est judgment and morality have been in hazard of destroying themselves to get rid of it. Before I was aware that these pains were the forerunners of ter- tian paroxysms, I commonly had recourse to bleed- ing, and without observing that it was attended with any ill effect: but of late years they never alarmed me, being well assured that they would go away of themselves, as the hot fit advanced. The vomiting and nausea, after washing the sto- mach two or three times with warm water, is com- monly allayed by draughts of salt of wormwood, lemon-juice and mintwater. And if a constant vo- miting or purging hinders the bark from being re- tained, small doses of laudanum should be joined OF TERTIAN FEVERS. 133 with it: but a moderate bilious discharge is com- monly beneficial, and therefore should never be sup- pressed. Restlessness and headachs are the inseparable companions of the hot fit; so that the sick must either be encouraged to bear them with patience, or must be amused with some innocent prescription till the sweats carry them off. When the headachs are constant and troublesome in the apyrexies, I order the limbs to be frequently bathed in warm water, and cataplasms of horseradish and leaven to be ap- plied to the soles of the feet. Hemorrhages of the nose are often of signal ser- vice, in removing the obstinate headachs and pains in the abdominal viscera, whether they are e directo or not; though for the most part they happen from the nostril of that side, in which the pains are fixed; for which reason they ought not to be hastily stopt, unless they continue too long, or come at a time of great weakness. When the belly is sore and painful to the touch, clysters and warm fomentations give great relief. When the pains are extremely violent, bleeding must be repeated: but during the hot weather we must not be too free with the lancet after the fourth pe- riod of the distemper; as the weakness commonly is then too great to admit of any such evacuation with safety. If the patient continues comatous and stupified longer than ordinary, we must endeavour to rouse him from that lethargic state by scarifying, cupping, and blistering the neck and back. M 134 OF TERTIAN FEVERS. Troublesome hiccoughs often cease, upon apply- ing cupping glasses without scarification to the pit of the stomach, and giving small doses of laudanum with tincture of castor. If acute pain and pulsation in the hip point out that a critical abscess is about to be formed there (a case that hath occurred to me five or six times), it must be brought forward by cupping glasses, and ca- taplasms applied to the place; and as soon as a fluc- tuation can be perceived, it must be opened by a deep incision; otherwise, the matter being lodged under the posterior double edge of the glutaeus ex- ternus, instead of pointing outwards, may insinuate itself betwixt the muscles of the thigh; or may per- haps work its way into the cavity of the pelvis, by the hole through which the musculus pyriformis, and the sciatic nerve pass out; which seemed to be the case in one man, who had first an abscess in his right hip, and some time afterwards another in the left, and died consumptive from the immoderate discharge. Parotids must also be brought to suppurate as soon as possible: but these are not very common in Minorca; nor are they much to be wished for, being oftener symptomatical than critical. To conclude, as tertians personate almost all dis- tempers, (a) so there are but few disorders to which the human body is incident, that will not sometimes appear in the course of these fevers; and these, when importunate, must be mitigated, as in other acute diseases. (a) The yellow fever of Philadelphia in like manner has ap- peared to be an epitome of all diseases. OF TERTIAN FEVERS. 135 It has been already remarked, that whether the fever is cured by art or nature, there is a hazard of its returning within a fortnight or three weeks; nor could I ever fall upon any certain method of pre- venting one relapse after another, till the cold wea- ther, which commonly sets in about christmas, had braced- the solids, and given them sufficient strength to throw off the excrementitious humours by the proper outlets; for which reason I always advised those who were attacked in the beginning of the season, to leave the island, if their circumstances would permit, and not to return until the spring. And there are many instances of persons being greatly recovered by the change of air, even in the first two or three days of their being at sea. But if they were obliged to remain in the island, the best chance they had of escaping a relapse was to take a dose of the cortex every morning and evening, for several weeks; and now and then a gentle purgative, if a bitterness in the mouth, loss of appetite, swim- ming in the head, or sickness at the stomach, the common forerunners of it, should be perceived. But if, notwithstanding all precautions, the fever returns, the patient must be treated as in the first attack; with this difference, that as relapses are at- tended with less heat and inflammation, bleeding, especially in the fit, must be used with more caution, or altogether omitted, and vomits may be given with greater freedom. And, as they happen mostly in a cooler season, they do not threaten such immediate destruction, and consequently may be longer trusted without the bark, if you are disposed to attempt a cure by other methods; though that remedy must 136 OF TERTIAN FEVERS. never be delayed when the fits are violent or pro- tracted. In this manner the patient must be content to go on till the turn of the year alters the constitu- tion of his body, and restores him to his former health. It has been insinuated by some that a long con- tinued use of the bark was liable to bring on ner- vous complaints and lowspiritedness; but in the multitude of cases, wherein I have been obliged to make use of it, I have not been able to discover that it had these or any other ill effects, when given in the manner above mentioned. And as to its occasioning dropsy, I do not remember to have met with above one instance these ten years, where there was a pos- sibility of alleging that it gave rise to that distemper. It is not uncommon for a looseness to come on in the room of a relapse. Sometimes instead of a ter- tian a quartan supervenes; which nevertheless may be speedily taken off by the bark; but if left to nature alone it will probably continue to the spring; or per- haps first turn to a double quartan, and afterward to a triple quartan; which, as Celsus observes, is a dan- gerous distemper. (Lib. iii. c. xv.) With respect to the tertians, which now and then appear at other times of the year, they are more of a chronic disposition than those of the summer and autumn; the cold fits being longer, the hot fits less severe, and the intermissions, more regular and per- fect. Add to this, that they are not so commonly at- tended with critical eruptions about the mouth; nor do the sick discharge such quantities of gall either upwards or downwards; and the urine oftener de- posits a lateritious sediment: but so far is this sedi- OF TERTIAN FEVERS. 137 ment from being the criterion of intermittents, that I have frequently seen it in pleurisies, and other in- flammatory fevers; while in both tertians and quar- tans I have, for the most part, found the urine clear without any separation; and in tertians the sediment was oftener more like chalk than brickdust. Thus have I given the history of those fevers, collected from an almost infinite number of cases, carefully minuted in the chambers of the sick, with- out trusting to memory, or regarding what others had said on the subject before me, or advancing any thing but from reiterated examination. The obser- vations relating to the cure, which are by much the most material, have been confirmed again and again by the experience of all who have practised physic with attention, among either the English or Spanish inhabitants of Minorca; therefore I am in hopes that these remarks will not be altogether useless to the public. It is well known that contagious intermittent and remittent fevers of the tertian kind, are anni- versary distempers in several of the warmer climates both in Europe, Africa, and America; and even in the northern parts of Europe they are often epide- mical after extraordinary hot dry summers.* By all that I have been able to learn of them from authors, there is a great analogy among them every where: and though in some places they may require more or less copious evacuations than we find beneficial in Minorca, yet I am persuaded that it may safely be * Hoffm. Med. Rat. torn. iv. cap. iv. sect. i. Short's History of the Weather, &c Anno Domini 1237, 1540,1553,1574,1652, 1657, 1669. Wintringham, anno 1719; and Vanswiet. Comment. in Aph. Boerhaav. 767- M 2 138 OF TERTIAN FEVERS. laid down, as a general rule in all cases of danger, to give the bark liberally and without hesitation about the third or fourth period of the disease, whe- ther evacuations have been previously used or not. Which practice is agreeable to the observations of the ablest and most experienced physicians of diffe- rent nations; such as Morton* and Sydenham! in England, Bartholinf. in Denmark, Hoffman|| in Ger- many, Geoffroy§ in France, Rodriguez** and many others in Spain, Guidettus and Bianchi in Pied- inont,ft Torti in Modena,±4 Musitanus|||| in Naples, and Traversarius^j in Pesaro; nay even in aere Ro- mano, where Baglivi declaimed against the use of the bark with so much passion, Lancisi* has of late years, as well as the cardinal de Lugof and father Fabriij: formerly, had incontestible pi-oofs of its be- ing not only an innocent, but a necessary, powerful remedy in the cure of tertian fevers. * Exercit. de Morb. Acut. f- Epist. Respon. I. \ Ephemerid. German. j| Med. Rat. torn. iv. § i. c. i. obs. 5. § Mater. Med. torn. ii. ** Palaestr. Med. torn. ii. disc 12. ff Hist. Hep part iii. t j Therapeut. Special, sparsim. ||| Pyretolog. c-xxiii. fl Apud Lancis. 1. ii. epid. iv. c. viii. " Epid. sparsim. f Antym. Conyg. Pulv. Peruv.Vind. f Id. ibid. 139 CHAPTER IV. OF THE RASH, ESSERE, AND CHOLERA MORBUS. HAVING given an account of tertian fevers, which was the chief design of this treatise, I shall endeavour to bring my remarks on the other epi- demical diseases into as narrow bounds as possible, by passing over such circumstances as are taken no- tice of by the generality of authors. The cutaneous eruption which we call the rash, or prickly heat, is the sudamina or papula sudoris of the Romans, and the l2g»* of Hippocrates, (Aphor. § iii. No. 21.), who justly places it among the sum- mer diseases; it being so frequent in warm countries, that few people escape having more or less of it during the hot weather; though children are much more affected by it than others. It consists of nu- merous minute pimples, or rather small, round, red spots, just perceivable by the touch, as a kind of roughness on the skin, which break out on different parts of the body, especially after exercise or drink- ing cold water. This eruption is commonly looked upon as a sign of health; and indeed while it continues fresh on the skin, no inconveniency arises from it except a fre- quent itching: but if accidentally the pimples are driven in, by catching cold, bathing in the sea, or 140 OF THE RASH AND ESSERE. any other error in the nonnaturals, the case too often becomes dangerous. And I have constantly observ- ed, that those who had a great deal of this eruption in the summer, were subject either to fluxes, he- morrhages from the nose, or fevers, upon the alte- ration of weather about the autumnal equinox. Wherefore I commonly advised them, as soon as the slightest signs of a retrocession appeared, (such as sickness, headach, and preternatural heat) to lose some blood immediately, and make use of mild ca- thartics, vegetable food, and cooling acescent liquors: by which means the bad consequences above men- tioned, if I am not greatly deceived, have been frequently prevented, notwithstanding the vulgar prejudices against evacuations in this and other similar cases. The essere, so called by the Arabians, who first described them, though not uncommon in Minorca, appear much more seldom than the rash. They are hard, flat tubercles, of a pale colour and different forms, and break out chiefly while one is warm in bed, sometimes on one part, sometimes on anodier, occasioning such an intolerable itching, that it is impossible to refrain from scratching; and the more they are rubbed the larger they become. They sel- dom continue out above an hour or two at a time, but suddenly vanish of themselves, the skin reco- vering its natural colour, and come back again as unexpectedly as they went off; the patient having more or less anxiety about the pit of the stomach, during the time of their disappearing. The Spaniards call them ronchados, from roncho a nettle in the Castilian language, they having exactly the appear- OF THE CHOLERA MORBUS. 141 ance of swellings occasioned by the sting of nettles: in iNIinorca they go by the name of favas, probably from their frequently resembling beans in shape and magnitude. (6) It is commonly allowed by authors, and not with- out reason, that those who have this sort of eruption should make use of bleeding, purging, and proper alteratives; otherwise a fever is liable to ensue. (Vid. Sennert. lib. v. part i. cap. xxvi.) The essere, as has been already observed, often accompany tertian fevers, and appear most commonly in the hot fit. Sometimes I have seen them so nu- merous that the whole body was disfigured by them, and painted in many places with all the colours of the rainbow. In a few such instances, which con- trary to expectation proved suddenly mortal, the patient's death seemed to be occasioned by those fiery pustules being accidentally thrown upon the brain instead of the skin. For which reason, wher- ever I met with them in great abundance, I took care to make as liberal evacuations as the strength and age of the patient would permit, and proceeded speedily to give the bark; which effectually cures both them and the fever. As to the cholera morbus, it must be managed according to the method first hinted by Hippocra- tes,* and of late described more fully by Sydenham, (De Morb. Acut. § iv. c. ii.) To which I must add, (b) These eruptions now and then occur during the prevalence of autumnal fevers in the United States. * Cholerae morbo conferunt, si quidem dolor adsit, anodynaj venter autem superior, turn inferior potionibus humectantibus curandus. Hip. de Affect. 142 OF THE CHOLERA MORRUS. that if feverish complaints, or fixed pains in the belly or sides come on, after the evacuation is stopt, (as is frequently the case) it will be necessary to bleed and keep the belly open, (c) The Spanish physicians have often assured me, that they found nothing more beneficial 'in violent deplorable choleras than drinking of cold water: which practice is recommended by man}- of the ancients.* When the cholera morbus returns periodically, like a tertian, it must be cured as those fevers are; but it denounces much more danger when it attends the fits about the third or fourth period, than it does in the beginning of the disease. (c) Bleeding has been found necessary of late years to cure tlie cholera morbus in Philadelphia in many instances. The effi- cacy of cold water in this disease in Minorca (mentioned in the next paragraph) proves the correctness of that practice made use of by our author. * Sin autem omnia antiqua stercora dejecta fuerint, et biliosi humores transierint, biliosusque vomitus et distentio adsit, fas- tidium, anxietas, virium labefactatio, tunc frigidae aquae Cyathi duo aut tres propinandi sunt ad ventris adstrictioneni, ut retro- gradus humorum cursus cohibeatur, atque stomachus ardens refrigeretur. Assidue vero id, quum potam aquam vomuerit, facito. Aret. Cappad. de Curat. M. A. 1. ii. c. iv. See likewise Cash Aurel. de Morb. Acut. 1. iii. c. xxi, 115 CHAPTER V. OF THE DYSENTERY. BY perusing the accounts which I kept of the sick, while dysenteries were epidemical in Minorca, I find that they began three different ways. First, Sharp indigested humours flowing from the stomach, or (what seems to be more frequently the case) an increased secretion of the bile and other liquids necessary for chylification, produce a simple looseness; which gradually washes off the mucus from the intestines, erodes their membranes, and at last brings on severe gripes with bloody stools. Secondly, Others are seized with horrors, rigors, and all the train of feverish symptoms, which com- monly attend the first attack of acute diseases; and in a short time afterwards a painful frequent eva- cuation of slime streaked with blood ensues. Thirdly, Others have no preceding fever, but are seized at first with a twisting of the guts, which (as they express it) draws up their bowels into knots; and many, instead of griping pains, which shift from place to place, and come at intervals, have acute fix- ed ones in some particular part of the belly, which occasion complaints as various as their seat; some being tormented with stitches about the bastard ribs, interrupting their breathing freely, as in the pleurisy; 144 OF THE DYSENTERY. others with a pain reaching from one hypochondrium to the other, cutting them, as it were, in two; while others complain only of a pain about the pelvis, with a constant, fruitless, straining to stool; though the body is, for the most part, costive, or discharges no- thing but bloody slime. But in whichsoever of these ways dysenteries be- gin, in process of time the case comes to be pretty much the same; the intestines are irritated, inflamed, and ulcerated; a fever, for the most part of the pe- riodical kind, comes on; the constant stimulus in the bowels diminishes the cutaneous discharges^ and, of course, a greater proportion of fluids is thrown upon the guts; the flux increases, and what is discharged becomes more ichorous, and offensive to the smell; the strength decays; and death, or a tedious reco- very, is commonly the consequence. Upon opening the bodies of the dead, I have con- stantly found the great guts either entirely mortified, or partly inflamed, partly mortified, the rectum being generally most affected: in many I have seen scir- rhous tubercles (d) straitening the cavity of the colon in several places; in a few, there were small abscesses in the cellular membrane of the peritoneum conti- guous to the colon and rectum: sometimes the small guts were perfectly sound in appearance; but more frequently their lower part was inflamed, the convo- lutions being often preternaturally connected to each (d) The reader is requested to attend to the suddenness with which tubercles are formed in the dysentery. They render it probable that they are formed in the same sudden manner in the lungs, and that they are the consequence, and not the cause of that disease in the lungs which ends in pulmonary consump- tion. OF THE DYSENTERY. 145 other by membranes, as the lungs sometimes are to the pleura. In two people the omentum (e) was almost entirely wasted (the small remains of it being quite black), while purulent water was found in the cavity of the abdomen; in several it was inflamed and ad- hered both to the guts and peritoneum; for the most part the gall-bladder was full of dark bile, and the spleen, more or less, in a putrid condition. Almost all the dysenteries, which fell under my observation, unless they were speedily cured in the beginning, at best proved obstinate, and too fre- quently fatal, in spite of the many boasted specifics for this distemper; for which reason, whenever they are epidemical, the utmost diligence should be used in applying the proper remedies before the strength of the patient be exhausted, and the coats of the intestines too much injured. And even let the utmost care be taken of them never so early, the event is often dubious or unsuccessful; though among the common soldiers this seems frequently to be owing to a want of means for keeping them clean, and con- veniences for easing themselves, without being oblig- ed to get often out of bed, and expose their bodies to the open air. Which conveniences it were to be wished, that those who have the direction of our (c) The exhausted state of the omentum of fat, or its total destruction, generally attends chronic diseases which end in death, except in those cases in which the functions of the liver are impaired. An inference has lately been made from these facts in favour of the design of the omentum being to secrete fat, to be conveyed to the liver in diseases which impair the ap- petite and digestion, in order to be converted by a secretory process into chyle for the nourishment of the body. N 146 OF THE DYSENTERY. i fleets and armies, would order to be provided both in the ships and hospitals. (/) I shall not enter upon a minute description of all the rules necessary to be observed in the cure of dysenteries; but only point out such methods of treating the sick, as experience taught me to be the most beneficial. When they begin like a simple diarrhoea, without fever or fixed pains in the belly, the first thing to be done, is to empty the intestines of their acrimonious contents as soon as possible: and the most efficacious remedies for this purpose, as far as I know, are the radix ipecacuanha and the vitrum antimonii ceratum. The latter I used to give from five to ten grains early in the morning: of the former I directed ten or fifteen grains in powder, to be divided into three doses, and to be taken in the forenoon at the interval of two hours, or an hour and a half between each dose. The most common effect of both was to procure a thorough evacuation upwards and down- wards during the day; and they often threw the pa* tient into a sweat the ensuing night. The same remedies I have likewise found to be serviceable in obstinate relapses of intermittent fe- vers: but I prefer the ipecacuanha, as being certain in its operation; whereas the other sometimes did not produce the intended discharge, at other times occasioned greater commotions than were expected. Nevertheless, I must acknowledge that now and then, {f) In some of the Spanish hospitals leather is made use of instead of a bed pan or linen to receive the stools. It is easily removed, and when washed and dried, may be employed as often as it is required OF THE DYSENTERY. 147 in desperate bloody fluxes, I have known the anti- monial medicine to be successful, after every thing else had been tried to no purpose. But I return to the method of curing them in the beginning. At first I repeat the abovementioned evacuations every other day for three or four times, and after- wards at greater intervals, if the disease continues; endeavouring, in the meanwhile, by proper drinks, to blunt the acrimony in the first passages, and de- fend their sensible membranes from being eroded; and every night at bedtime, I give a small dose of opium, sufficient to mitigate pain, procure rest, and promote perspiration, without keeping the sick in a constant state of stupidity, or* preventing a due discharge by stool; as I have seen some do very injudiciously by the too liberal use of anodynes, (g) But when the dysentery began in the second or third way above described, which was commonly the case in the year 1747, I confided principally in the early use of the antiphlogistic method, with a view to hinder the guts from being farther inflamed and ulcerated. Wherefore, when I was called in time to young people, I took away ten or twelve ounces of blood immediately, and afterwards repeated the operation once or twice at proper intervals, according as the violence of the pain and degree of fever indi- cated: at the same time I ordered emollient clysters and fomentations to be frequently made use of; and plenty of warm, soft, diluent liquors, for common (g) The practice of our author in the use of purges and opiates, accords with that of the most successful practitioners in the United States. 148 OF THE DYSENTERY. drink; shunning opium as much as the intolerable torture of the distemper would permit. As soon as the fever was somewhat abated, and the violence of the pains assuaged, I next endea- voured to procure a sufficient discharge by stool. For it is to be observed, that wherever the ilium, colon, or rectum are inflamed, hardened excrements are, for the most part, either the cause or the conse- quence of the disease; nor can we hope for a com- plete recovery while such offensive matter remains in the bowels; wherefore purgatives of the mildest kind may first be made use of, such as whey, weak broth, sweet oil, solution of manna, cremor tartari, &c. proceeding by degrees to the more active, till the end proposed be obtained; after the same man- ner as we are directed to do in Sydenham's bilious cholic; which indeed is a disease nearly allied to the dysenteries I am now treating of, and is always fre- quent at the time when they are epidemical. In both cases, when other means have failed, six or seven grains of calomel with a grain of opium at night, after the use of the semicupium, and a purging apo- zem made of senna, manna, and sal catharticum the next day, have proved successful, and brought off a prodigious quantity of round, hard, fetid lumps, to the great relief of the patient; nor is it easy to con- ceive how so much had been collected, or where it had lodged so long, as in some cases I have observ- ed: the patient having eaten nothing for two or three weeks, that could furnish much excrement, and dur- ing that time had taken several clysters and common cathartics, which brought away liquid stools. (A) (A) This fact has been mentioned among others as a proof OF THE DYSENTERY. 149 Having by such methods removed the inflamma- tion of the intestines, and dislodged their irritating- contents, the tenderness of the bowels must be miti- gated by anodynes, and the use of such medicines, as supply the want of the intestinal mucus. By these means dysenteries, if taken in time, have been speedily carried off; as well as the tenes- mus, which is a disease very nearly allied to the for- mer, and equally fatal, whatever Celsus may allege to the contrary. (De Med. lib. iv. c. xxi.) But if they were neglected in the beginning, or did not soon yield to the remedies above mentioned, the case commonly became inveterate and perplexing; the same medicine which gave relief to one, often doing harm to another, as Hoffman justly observes. (Med. Rat. t. vi. § ii. c. vii.) In general, it answered best to avoid such diet as would afford a large quantity of putrid, irritating excrement; to drink plentifully of mild gentle detersive balsamics; to give liquids of the same kind in clysters; in short, to pursue with diligence the directions given us by the great Boer- haave in his Aphorisms, (No. 96&, 976.) with this addition, that it was absolutely necessaiy to give opium twice a day, in order to obtain some respite from perpetual torment, and gradually to increase the dose from half a grain to five or six, as use made it familiar; and once or twice a week or oftener, as the strength would allow, and the symptoms indica- that the liver performs the office of a chylopoetic viscus, and that the faeces which are discharged during the long intervals of eating, are formed from the chyle that is secreted from th© fat of the omentum, and other parts of the body, and which is absorbed during the continuance of the disease. N 2 150 OF THE DYSENTERY. ted, to hinder the acrid matter from being accumu- lated in the intestines by giving clysters, cathartics, or small doses of ipecacuanha. If by these means the patient can be kept alive during the first severe winter weather, he stands a good chance of holding out to the summer, which commonly restores him to his former health, when he must be weaned by degrees from the use of opium; from the continuance of which medicine, in such cases, I have never found any ill effects ensue; on the contrary, I could name many people who have been obliged to take it in this manner from Septem- ber to the following June; and as far as I am able to judge, it is to the opium they are chiefly indebted for their lives, and the perfect health which they at present enjoy. (?) The great similitude there is in many respects between tertian fevers and dysenteries, induced me frequently to make use of the bark in the last named disease. When the fever and gripes were regularly exasperated, either every day or every other day at stated periods, it has often effectually put a stop to both; (&*) especially if the exacerbation began with dullness, and terminated in sweats: At other times (»') Hundreds of patients with chronic dysentery and diarrhoea can testify to the truth of this account of the safety and efficacy of opium as a chronic medicine. It prevents the patients having recourse to ardent spirits, over which it has the following ad- vantages, viz. it gives more prompt and certain relief, and the habit of using it, when it ceases to be necessary, is more easily broken. (i) In cases where the dysenteric symptoms become perio- dical, the editor has administered the bark with equal success in the intermissions of those symptoms. OF THE DYSENTERY. 151 it removed the fever, the flux continuing without much alteration. In some cases I have given it merely with a view to prevent the mortification of the intestines in the last stage of the distemper: but I am sorry to say that it was seldom so successful as I could have wished. K 152 CHAPTER VI. Of the Pleurisy, and other fnflammatory Fevers,fre- quent in the Winter and Spring. A HE anniversary epidemical fevers in Minorca may be divided into two classes, which at present, for distinction's sake, we shall call the summer and the winter fevers. The former break out in June or July, and cease about January, or somewhat sooner. The latter seldom appear before November, and are rarely seen after the summer solstice; so that one seems to be the offspring of excessive heat; the other of the sudden cold which the north winds frequently occasion. And as the same sort of weather recurs regularly every summer and autumn, so likewise do the diseases: whereas those of the winter and spring, agreeable to the variable disposition of those seasons, are neither so uniform nor so certain; being some years more frequent in one month, others in another. The summer fevers are by much the most universal, making up two thirds, or sometimes three fourths of the whole annual diseases, and attacking the inhabi- tants of every rank, whether natives or foreigners, without distinction: (/) whereas the others are less (/) The autumnal fevers constitute about the same proportion ef all the acute fevers of several of the middle and southern OF THE PLEURISY, &c. 153 injurious to the English than to the Spaniards; and especially to the peasants, whose houses are com- monly built upon rising grounds, and not so well adapted for keeping out the piercing cold of the winter, as sheltering them from the summer's heat; so that I have known particular corners of the coun- try almost depopulated, while the towns and villages escaped any remarkable mortality. Both these classes of fevers, and indeed almost all others which happen in that climate, whether prima- ry or symptomatical diseases, may be termed peri- odical, having remissions at intervals, more or less considerable: but those of the summer, as has been already observed, generallv assume some one or other of the tertian types, being worse one day and better the next alternately: whereas the winter fevers, though they often counterfeit tertians, especially in their beginning, yet for the most part have exacer- bations equally strong every day, coming on about noon with or without cold shiverings, and terminat- ing towards morning, sometimes with gentle sweats, sometimes without any sensible evacuation. It may likewise be remarked, that as the summer fevers are generally complicated with fluxes and painful obstructions in the chylopoetic viscera; so are those of the winter, with coughs, catarrhs, and topical inflammations of the vital organs, the brain, the lungs, the heart itself; and hence it is that the latter are more destructive in proportion to their states. The same disposition in winter fevers to appear with daily exacerbations and remissions which our author has men- tioned in the preceding paragraph, takes place in the United States, not only in the winter, but during the succeeding spring. 154 OF THE PLEURISY, &c. numbers. Notwithstanding which, as the former are much more constant and universal, if we calculate one year with another, we shall find that " the au- tumn produces the most acute and most fatal dis- eases of all seasons; and the paroxysms in the even- ings bear some resemblance to it. For as the day of any particular disease is to the year that contains the period or circle of diseases, so is the paroxysm in the evening to the autumn." (Hip. de Morb. Vulg. 1. ii.) And indeed the conformity between such of those diseases as are described in the Hip- pocratical writings and the appearance of them at this day in climates near the latitude of Greece, will be abundantly evident to every one who considers the preceding account with any degree of attention. Having premised those general reflections, in or- der to give the clearest idea I can of the winter fe- vers, I shall describe them as they appeared during the last month of the year 1745 and the first part of 1746, when the uncommon destruction which they made among the English rendered thern more im- mediately the object of my attention; and as the generality of them is called mal de costat by the vul- gar, and the pleurisy by physicians, from their being accompanied with pains in the side, I have, in com- pliance to prevailing custom, retained that name in the title of this chapter, though it will appear in the sequel, that they ought rather to be termed peri- pneumonies, agreeably to the observations of Ze- chius,* Hoffman,f and others. Those pleurisies began commonly like an ague fit, with shivering and shaking, flying pains all over * Apud Bonet. Sepulchr. Anat. lib. ii. § iv. f Med. Rat. torn- iv. § 2. cap. iv. OF THE PLEURISY, &c. 155 the body, bilious vomitings and purgings, which were soon succeeded by quick breathing, immode- rate thirst, inward heat, headach, and other feverish symptoms. In a few hours the respiration became more difficult and laborious; the most part of the sick being seized with stitches in their sides, striking upwards to the clavicle, and shoulder blade; oblique- ly downwards along the cartilages of the bastard ribs; or else darting across from the breastbone to the vertebrae of the back; so that they could neither cough, nor make a full inspiration without great pain. Manv complained chiefly of a load and op- pression in their breast, as if a millstone had been laid upon it; some of a heaviness and fluttering about the heart, which at one time seemed to glow with extraordinary heat, at another to be chilled with c-old, as if it had been dipt in icewater. In a few of the sick those complaints preceded the fever, in others they did not come on till the day after, (m) In the progress of the disease it was not uncom- mon for the pains to move about in the thorax from one place to another. Sometimes they would shift from the breast to the limbs, and of a sudden re- turn to the bowels; and I have seen cases wherein, after leaving one side, they have attacked the other unexpectedly, and proved fatal in a very short time. The left side of the thorax was not near so liable to be affected as the other; forty-two out of sixty pa- tients who were seized about the same time, having had the disease in the right, (ii) But whichsoever (m) The whole of this description of the pleurisies of Mi- norca, accords with the symptoms of what are called bilious pleurisies in the United States. (n) The greater disposition of the right side to be affected in 156 OF THE PLEURISY, &c. side was affected, the sick lay easiest on the oppo- site; though the generality were obliged to lie upon their backs, or to sit up in bed with their heads erect. Many were drowsy and inclinable to sleep; but they raved at intervals, or were much disturbed with ex- travagant dreams. Some laughed in their sleep; others would awake in a fright and start out of bed, imagining that the house was in flames; that those about them were endeavouring to push them over a precipice; to pierce their sides with daggers; to bind them down with cords, or iron hoops, and things of the like nature. In the meantime the external heat of the body was in several very moderate; in some less than natural; but for the most part it was so intense as to raise the mercury in Fahrenheit's thermometer to the 102d degree, and often in the afternoon to the 104th. The pulse was likewise very variable, not only in different persons, but in the same person at different times; and, in respect to its strength, in different arms, that of the pained side being most obscure; and I have frequently found it like that of a man in health, or even slower than natural,* while the pleurisies mentioned by the author was probably the effect of a combination of bilious fever with them, which disposes to hepatic pains and obstructions. The fixed position of the patient mentioned in the next sentence, shows the pleurisies to have partaken in a degree, of the character of the pneumonia notha. * Pulsum in pleuritide minus celerem, aut fortem (febre ta- men acuta in summo vigore nihilo minus subsistente) saepius notavi: pulsus igitur celeritas et magnitudo non semper cum febre inflammatoria sociantur. Qui in pleurae aut pulmonum in- flammationibus pulsui nimium fidunt, decipiuntur, Sic. &c. O'Connel de Morb. Acut. p. 235. OF THE PLEURISY, &c 157 the patient was in the greatest danger; so that it could neither be depended upon as a prognostic sign,. nor as an indication of cure. Nor was the colour or consistence of the blood more to be trusted; in many it had a white or pale yellow crust, the serum being of the same complexion; but for the most part it was red and florid. It frequently changed its appearance, in the space of a few hours, in the same person; what was drawn in the morning having a crust; that in the afternoon none, et vice versa, (o) And I could never positively determine which sort afforded the best or the worst prognostic. The signs from which one could pronounce the patient's recovery, with the most certainty, were his being able to sleep sound in the natural posture, and to make a full inspiration without difficulty, while his thirst and inward heat were moderate. Beside some abatement of the fever, which com- monly happened every morning, it was remarkable, that upon the third day, or beginning of the fourth, there was frequently a great remission, sometimes a total cessation of every violent symptom; so that the sick were thought to be out of danger: but on the fourth or fifth a delirium suddenly came on, or the breathing became more difficult than ever, and one or both of those symptoms increasing hourly, the patient expired in a day or two, either suffocated or raving mad; unless nature or art assisting, he (o) It is evident from the state of the skin, the pulse, and the blood, that this pleurisy partook a good deal of a malignant nature. The changes in the appearances of the blood drawn at different times of the day, show how much they are influenced by the varying force of the blood vessels. 158 OF THE PLEURISY, 8cc, had the good fortune to escape by means of some of the evacuations to be hereafter mentioned. It sometimes happened that the remarkable remission fell out on one of the days between the fourth and the seventh; in which case the exacerbation succeed- ed on the following day. (/>) Out of twenty-one patients, whom I lost by this distemper, four died upon the fourth day; three the fifth day; three the sixth; three the seventh; three the eighth; two the eleventh; one the fourteenth; and the remaining two, though the day cannot positively be de- termined, yet from some circumstances, it is evident, that it must have been the fourth or fifth. And-indeed such was the rapid progress of those mortal pleurisies, that if any of them survived the seventh day, it seemed to be entirely owing to bleeding. (p) The whole of this paragraph is a further illustration of the bilious and malignant character of the pleurisies described by our author. The same supposed " remissions, and total ces- sation of every violent symptom," frequently took place in the yellow fever in Philadelphia. The editor differs from the author in supposing them to be remissions. On the contrary he believes them to be the effect of the system being reduced by a severe paroxysm of fever, below the points of sensation and reaction. That this was the case in the pleurisies, he infers from the fa- vourable issue of the practice of our author, mentioned in a sub- sequent part of his work, where he informs us that the loss of thirty or forty ounces of blood within the first three days, and bathing and blistering the legs, prevented what he has called " the insidious intervals," or " treacherous remissions" of the disease, and induced such " commotions" in the system, or so severe a paroxysm, as to require bleeding and blistering to subdue it. The same copious bleedings prevented similar ap. parent remissions in the yellow fever of Philadelphia, or if they had not been used to a sufficient extent, the repetition of them relieved the system from its insensible and oppressed state, and thereby created a fever, and thus saved life OF THE PLEURISY, Sec. 159 I examined fourtee.en of the bodies, in all which the lungs were principally affected; whilst in several the pleura was perfectly sound, or only slightly at- tached to the lungs, which is a common case in adults, as every one knows who is accustomed to dissections. In many the lungs were converted into a hard liverlike substance, and sunk in water; in some the diaphragm was inflamed; in others large firm polypi were taken out of the ventricles of the- heart and large vessels adjoining, (y) Abscesses, or rather half formed abscesses, with a sanious ichor, and a rotten gelatinous substance, instead of con- cocted matter, were frequently found, even in those who died so early as the fourth day, either in the lungs, or between the lungs and pleura, where they adhered, or between the membranes of the medias- tinum, near the diaphragm. And these abscesses had sometimes emptied themselves into the cavity of the thorax, so that the lungs floated in purulent serum; their external membrane, and likewise the pleura, being greatly thickened and converted, as it were, into a white crust,* like melted tallow grown iq) It appears from our author's dissections that polypi as well as tubercles are formed by acute as well as chronic diseases. * I am now doubtful if this crust was the pleura and external coat of the lungs, changed from a natural state by soaking in a purulent fluid, or if it was not altogether a preternatural sub- stance, formed by fluids deposited on those membranes, and compacted together by the motion of the lungs; for I have lately been informed by Mr. Hunter, that, in those who die of internal inflammations, he generally finds the surface of the ca- vities and the bowels furred over, as it were, with a thick slough of an ash colour, somewhat inclining to yellow, which he had an opportunity of observing in all the different degrees of con- 160 OF THE PLEURISY, Sec cold, part of them being eroded and detached from the rest. In some bodies the pericardium was full of puru- lent serum, its internal membrane and the outer sur- face of the heart, being affected in the same manner as I have just now described those of the lungs and pleu- ra. In two people whose heads were examined, the si- nuses of the dura mater were stuffed and distended with blood, the membrane itself being sound, and the pia mater, together with the plexus choroides, was in- flamed and much thicker than in a natural state. In one person, whom I imagined to have died of a pleurisy, the lungs and pleura were sound; but there were polypi in the heart, the diaphragm was inflamed, and a large abscess was found in the right lobe of the liver, which had discharged itself into the abdomen, where much purulent stinking matter was collected; part of the colon and teguments near the liver being sphacelated, the rest of the guts in- flamed, adhering to each other, and beginning to mortify. This man, for the first four days of his distemper, had no great pain; on the fifth and sixth day it became violent; after this he expectorated freely, which gave hopes of his recovery to the sistence, between a soft mucus slightly adhering to the parts, and a solid fibrous lamella, so closely attached to them, that at first view they appeared to be inseparably united: yet after maceration in water he could peel off the whole of this slough from the smooth, sound, natural membrane which it covered. This observation confirms Haller's opinion, that the membra- nous adhesions, so frequently met with between the lungs and pleura, are generally formed by the coagulation of the watery fluid which oozes from the exhalent vessels of these parts. See Lin. Prim. Physiolog. No. 262. OF THE PLEURISY, Sec. 161 twelfth, when he died, contrary to expectation, put- ting me in mind of a prognostic in Hippocrates,* which seemed to be applicable to his case, (r) Among the natural evacuations which terminated these pleurisies, the most frequent was a plentiful expectoration without hard coughing. When this discharge began early, and continued freely, it kept off or mitigated the dangerous symptoms so liable to come on about the fourth or fifth day, and the fever disappeared about the seventh: but if the spit- ting did not begin before the exacerbation of the fourth or fifth day, it often proved insufficient to save the patient. If he did recover, the fever seldom left him before the fourteenth day, and frequently continued much longer. Hippocrates describes the colour and consistence of the expectorated matter, which generally prog- nosticates death or recovery. (Prsenot. Coac.) But at the same time he takes care to inform us, that every sort of spitting which does not remove the pain is bad; and every sort that does remove it is good: the latter part of which remark I have seen verified in some who owed their lives to that evacu- ation, though the matter was always thin, crude, and ill-coloured. The next critical discharge to be mentioned is a copious efflux of urine, which soon after being made turns thick, and is either of a pale red, letting fall a * Quibus autem pleuriticis doloies initio mites sunt, ingra- vescunt autem quinto aut sexto, facile ad duodecimum usque perveniunt; ac raro illi servantur. Praenot. Coac. (r) The result of this dissection shows the uncertainty of no- sology, and the necessity of our remedies being governed by the state of the system rather than by the name and seat of a disease 02 162 OF THE PLEURISY, Sec. lateritious sediment, or milky, as if mixed with lau? dable pus, and deposited an equal smooth white one. Such urine alone terminated the disease in some; and in many it proved an assistant to the expectoration. (*) Sweats were common in these pleurisies: in the beginning indeed they were oftener symptomatica! than critical: but after the obstructions of the head and breast were removed by the evacuations above mentioned, they seldom failed of coming on to abate the fever, and complete the cure. And though they did not always fall out on the critical days, yet it is remarkable, that those which were most profuse, and brought about the greatest changes, which really happened on the 4th, 7th, 9th, 11th, 14th, 17th, and 21st day, much more frequently than on others. This is a circumstance to which I had not always attended, though I find from my notes that it is a true one. It was common for those diseases to begin with a vomiting and purging of green or yellow bilious matter: but there were few instances where either of those evacuations could be reckoned critical, ex- cept in one man who laboured under a dry pleurisy with crude urine, and had got to the eleventh day, with the utmost difficulty, when a purging of porra- ceous bile came on, and gave a turn to the distem- (s) Nature often employs this mode to relieve herself of re- dundant fluids, but not always with success. Physicians should follow her in availing themselves of the kidneys as well as the bowels, blood vessels and pores, to discharge violent diseases j>jro the body. OF THE PLEURISY, Sec. 163 per, which afterwards went off gradually by sweat and expectoration. One person who had a violent pleurisy in the right breast, and had been four times bled, was seized with a hemorrhage from the right nostril on the se- venth day; and after losing four or five ounces, a most profuse universal sweat came on, and put him out of danger. (?) Another way which nature took to relieve herself, was, by translating the morbific matter from the bowels to the surface of the body. In three people the disease was, immediately after its invasion, changed into the erysipelatous fever, described by Sydenham, and was cured as he directs. In seven or eight people the fever and all other complaints va- nished the second or third day, an erysipelas ap- pearing on the inferior extremities, which in some fell lower and lower every hour, and soon made its exit by the toes; in others, being more of the nature of a phlegmon, it settled in one of the legs, and form- ed an abscess, which degenerated into fistulous ul- cers, and proved very difficult to be cured, (w) By reflecting upon these cases, and considering that an erysipelas of the bowels would spread from (0 This fact is important, inasmuch as it shows, 1st, that the loss of a very small quantity of blood in the close of a disease is often attended with the same beneficial effects as the loss of a large quantity in its first stage; and 2dly, that a very small ex- cess in the quantity of blood will keep the system above the salutary sweating point. («) The whole of this paragraph is calculated to estabhsh a belief in the unity of disease. The erysipelas has in several in- stances preceded the plague and yellow fever. It was in these cases probably brought on by a similar cause. 164 OF THE PLEURISY, Ecc. place to place inwardly, as it does on the skin, I could account for several appearances in the predo- minant distempers, which it first seemed somewhat extraordinary; such as the inconstancy and mutabi- lity of the pains, and the frequent alteration of the pulse and breathing, according as the morbific mat- ter shifted its situation, and fixed upon different or- gans, the heart, the lungs, the midriff, or containing membranes of the thorax. And I imagined that the treacherous remission, so frequent on the third or fourth day, happened whilst the morbific matter was shifting from the breast; which after being reas- sumed into the mass of blood, and falling upon the head, or returning again to the lungs, often occasion- ed tragical effects. When those pleurisies first became epidemical, their quick progress and uncommon mortality sur- prised me greatly. I attempted to cure them by bleeding once or twice a day, if the complaints were violent, as I had always used to do in inflammatory fevers: but the remissions in the mornings some- times induced me to omit the operation; and the cessation of the symptoms, which generally happen- ed about the third day, made me imagine that the danger was over; so that before the patients were blooded above two or three times, the exacerbation came on upon the fourth or fifth day, and defeated all attempts by bleeding, blistering, or otherwise to relieve them. Those unforeseen events startled me greatly, and led me again to review the whole progress ol" the disease, its symptoms, and issue. I had observed that some escaped by means of expectoration and OF THE PLEURISY, Sec. 165 purulent urine, without much assistance from phle- botomy: and considering the periodical revolutions of the fever, the quick transition of the stitches from one part to another, together with the prevailing colour of the blood, as well as that of the spitting, and other excretions, I was apprehensive that those were what authors call bilious pleurisies, which they allege are exasperated by large evacuations:* parti- cularly Duretus,| who exclaims with great vehe- mence against those physicians wjio trust principally to bleeding in the cure of those diseases, without waiting for the natural evacuations. These motives induced me to use the lancet with more caution; and to rely chiefly on the speedy application of blis- ters for restraining the symptoms. But this manage- ment proved less successful than the former; and I was convinced in a short time that, instead of too much, too little blood had been taken away in the beginning; having been sometimes misled by the insidious intervals of the disease; at others having trusted too much to the faint attempts which nature made to relieve herself by expectoration and urine j the latter often becoming crude on the fourth day, as the delirium advanced, though it had promised fair on the second or third; the former frequently being checked about that period of the disease, by the im- moderate heat of the lungs rendering the matter * Ballon. Epid. Sparsim. Bianch. Hist. Hep. p. iii. ) The reader is requested to compare this account'of the effects of copious bleeding in preventing the " insidious inter- vals, and treacherous remissions" of the disease mentioned in page 158, and referred to by the editor. (x) Our author was not misled by the supposed weakness of OF THE PLEURISY, Sec 167 If I was called, for example, in the morning, the patient was immediately laid in a horizontal posi- tion, and bled at the arm until his pains abated, or he began to faint; neither of which commonly hap- pened before 16, 20, or 24 ounces were taken away. If the symptoms continued, I ordered about the same quantity to be taken from the other arm in the afternoon, without regarding the urine, expectora- tion, or appearance of the blood. Next morning, though there might be a great alteration for the bet- ter, yet, if there was the least room to suspect that any obstruction remained in the head or breast, the bleeding was repeated: and by carefully weighing the blood* I found that between forty-eight and fifty-four ounces were frequently taken away during the first 24 hours of my attendance. This sudden copious evacuation commonly procured a cessation of all violent symptoms, and afforded an opportunity to give an antiphlogistic purge the next day. But if the symptoms did not cease, or if the pains and dif- ficulty of breathing returned the day after the purge had been given, or if there was reason to suspect from the headach, giddiness, tingling of the ears, and disturbed rest, that the brain was in danger of being affected, I had again immediate recourse to bleeding, taking away at different times to the amount of 12, 18, or 24 ounces, in the space of a day, either by the lancet or cupping glasses, or both, old age in the use of the lancet. Experience proves it to be more necessary under equal circumstances in that stage of life, than in any other. * In weighing the blood, I used the island weights, fourteen ounces of which answer nearly to sixteen ounces avoirdupois. 168 OF THE PLEURISY, &c. as occasion required; by which means the impending storm was happily averted; and as soon as the com- motions were quelled, the purgative was repeated every other day for three times, unless some of the critical evacuations appeared with such visible good effects as rendered it unnecessary. In this manner I found with Sydenham, that pleurisies of the most fatal tendency might be hap- pily cured in the space of a few days; and with as much certainty as any distemper whatever. And it was no less remarkable to observe, how quickly the sick recovered their usual health and strength, not- withstanding the great loss of blood which they had sustained; while many, who had been bled more sparingly, continued in a languid, infirm state for months, without being able to get rid of the cough and pains in the breast, (v) (y) The copious bleeding used with so much success by our author in the treatment of bilious pleurisies is founded upon the system labouring under two distinct and violent morbid actions, the one in the lungs, and the other in the stomach and liver. The same disease yielded only to copious bleeding in the winter of 1794-5 in Philadelphia. Nearly all died who were not bled , twice as much as in a single pleurisy, or inflammatory bilious fe- ver. This copious depletion by the lancet not only saved life, but prevented, according to Dr. Sydenham, a distressing and dangerous cough. Our author discovers his usual good sense in continuing to bleed, while the symptoms of the disease retained their early violence, without any regard to the state of the urine, expectoration, or the blood. Even the pulse in such cases should not regulate the use of the lancet. Let it not be sup- posed from what has been said, that the bilious pleurisy ap- pears in no other form than that which has been mentioned. It sometimes assumes in the United States, the symptomfc of the typhoid and typhus states of fever, in the former of v%ich bleeding is forbidden, and in the latter, bark and opium are the most effectual remedies. OF THE PLEURISY, Sec. 169 Hitherto I have only mentioned the capital re- medies made use of in the cure of those distempers. But it may not be improper to take notice of some other collateral helps, which were generally used in the several ways of treating them above described. In the first place, the sick had warm barley water with oxymel for common drink; and nitrous anti- phlogistic medicines in the first days of the distem- per; their bellies being kept open with clysters. Oily linctuses were exceedingly useful in allaying the cough; and small doses of anodynes were often necessary, both for that purpose, and to procure sleep when the height of the distemper was over. If the pleurisy began' with a bilious vomiting, it was expedient to promote that evacuation by large draughts of warm water, in order to carry it off the sooner. To ease the pains in the breast the large leaves of the opuntia, toasted in an oven, and split through the middle, were frequently applied: these being thick and succulent, retain the heat a long time, and pro- duce all the good effects that attend anodyne emol- lient cataplasms and fomentations; as I have fre- quently experienced in tertian fevers, dysenteries, and other diseases with inflamed bowels, as well as in this disease, since I first learned the virtues of the leaves from the natives of Minorca. After bleeding twice or thrice, blisters laid upon the part affected wtr| often successful in removing obstinate stitches: but nothing affords such certain and immediate relief as the scarificator and cupping gfcjss; insomuch that among the many trials which I have had of them, I do not remember an instance P 170 OF THE PLEURISY, Sec. where they did not either carry off the complaint en- tirely, or mitigate it considerably: but my glasses were both wider and deeper than those commonly used in England. The phrensies and anginas, which now and then ap- peared during this constitution of the air, required the same method of cure: and as to the chincough, which was so fatal to children, the chief difference between it and the pleurisy seems to have been, that in one the morbific matter was thrown into the ve- sicles of the trachaea, in the other it stagnated in the extremities of the pulmonary arteries. During the same period of time catarrhal fevers appeared among the adults, attended with coughs, pains in the head and bones, and frequently a deli- rium; some of which suddenly terminated on the seventh day by profuse sweats; but most of them had partial crises sooner, and went off by degrees. When large bleeding was neglected in the beginning, they were liable to degenerate into pleurisies. This was likewise the case with the tertian fevers; and indeed it was remarkable that not only all acute dis- eases of this season, but even accidental hurts and bruises required more plentiful evacuations than or- dinary; so inclinable was this constitution of the air to promote inflammations, (z) I shall conclude this chapter with a paragraph or two from some letters, occasioned by the pleurisies of which we have been speaking, in order to confirm what has been said on them by the testimony of my (2) Our author discovers his education in the schools of Hip- pocrates and Sydenham by admitting an inflammatory constitu- tion of the atmosphere, and its influence upon all diseases, OF THE PLEURISY, Sec. 171 friend Dr. Font, an eminent physician of Ciudadella in Minorca, who has deservedly enjoyed a most ex- tensive practice for upwards of thirty years. Didaco Fo?it, M. D. G. C. S. —Novus annus funera densa produxit, grassante febre inflammatoria, quae caput et organa respiratio- nis potissimum afficit, modo pleuritis; modo peri- pneumonia, interdum phrenitis, interdum paraphre- nitis adpellanda. Hie morbus, ut vehemens, largis et repetitis vensesectionibus, cum interposita catharsi, in herba felicissime jugulatur. Complures liberale sputum, sine multa sanguinis jactura, periculo eri- puit. Nee desunt, quibus urinae purulentae fluxus diu perseverans, saluti fuit. At, nisi istius modi auxilia mature accedant, vas aegris! nam postquam morbus per triduum impune saeviit, altasque egit radices, fero plerumque medicina paratur; et neque vense- sectiones, neque epispastica, neque cucurbitulae, ne- que pectoralia tantopere decantata, impedire valent, quo minus, juxta Hippocratis effatum, u Septimo die vel celerius succumbant, aut mente lassi, aut orthopnea suffbeati." A te itaque peto, vir experientissime, ut dato otio, his quaesitis responsum praebeas. Annon pleuritis morbus anniversarius in hac in- sula, et quibus mensibus? An semper febrem continuam, cum celeri pulsu, acri calore, &c. comitem sibi adsciscat? An potius febri periodica remittente tonjungatur? Nonne tutius est, morbi resolutionem per venaS- h 172 OF THE PLEURISY, Sec. sectiones, quam primum tentare, quam coctionem <-t crisin naturae praestolari? Ubi resolutio tentanda est, qua mensura et quibus intervallis cruorem detrahere conveniat? Datum Magone tertio die Maii, S. V. anno M,DCC,XLVI. G. C. Diadacus Font, S. —Anniversarius hac in parte insulse morbus est pleuritis, hiemeque viget, quantum ex usu observavi; et ubi rigida hyems plus justo prolongatur ad me- dium aut finem veris excurrere solet; immo anno 1730, quamvis solito modo procederent tempestates, memini hunc morbum, cum aliis inflammationibus internis, magnam stragem fecisse; aegris vel mente lsesis, vel orthopnea suffocatis. Pleuritis non semper febrem acutam continuam habet adjunctam cum siti, cau.ie, et celeri pulsu: imo potius in ipsius principio febris est fere semper mi- tis; pulsus quoad celeritatem, parum distat a natu- ral!, calorque non est nimius, nee mordax; et in multis propensionem ad somnurn observavi. Nequa- quam vero, licet ita ingrediatur, Ieniter tractanda est; sed eodem modo ac si cum vehementi febre invasisset. Praeterea, pleuritis saepe sociatur febre quae -perio- dice remittit, et intenditur, modo quotidie, modo de tertio in tertium,* Et aliquando sola febris tertiana intermittens adest; sicuti observavi in quatuor aegris, quorum unus in initio septimi paroxysmi e vita decessit. * Vide Galen. Avicen. &. Mercurial apud Bianch. p. iii. Schol. 25. h. Spigel. de Semitertian. cap. iii.. OF THE PLEURISY, Sec. 173 Quoad curationem; ubi tempestive vocatus suni, primo scil. die, vel secundi initio, deposita mora, san- guinis circiter quatuor libras, partitis vicibus, nuch- themeri spatio, si aeger robustus sit, detrahere jubeo; qua subita et copiosa evacuatione morbus quando- que in herba resolvitur. Sin vero persistat, ante diem quartum, totidem fere sanguinis libras, partitis vicibus, noviter extraho: et similiter prosequor, licet ante diem quartum magna et notabilis omnium svmptomatum remissio contingat. Quae quidem re- missio talis et tanta esse solet, ut aeger et reliqui rem jam in tuto putent; et ipse olim ita existimavi, donee infausti eventus aliter docuissent. Quippe veniente die quarto, aut quinto, supra modum ex- acerbantur svmptomata, et furente nova procella, aeger qui mox convaliturus sperabatur, orco traditur: quod nulla alia methodo quam supra praescripta prae- cavere potui; diluentibus interim, expectorantibus, clysteribus, cucurbitulis et epispasticis, pro ratione symptomatum, diligenter adhibitis; ut et purgantibus, post septimum diem. En methodus medendi, qu3e meis et aegrorum votis respondet! Ex centum qui corripiuntur, nonaginta, aut in initio resolutione, aut postea manifesta crisi servantur. Quae crisis, aut per sudorem, aut per expectorationem, aut per urinae profluvium, modo sanguinolentae, modo puriformis, aut per diarrhceam perficitur; adjutis vitae viribus, sanguinis evacuatione, et supra memoratis remediis legitime exhibitis. Quibus inter initia spretis, mors ut plurimum succedit. Datum Civitellae Maii 26, S. N. anno M,DCC,XLVI. P 2 174 CHAPTER VII. OF THE SMALLPOX. 1 HE smallpox were twice epidemical in Minorca, while I resided there, viz. in the year 1742, and 1746. Without entering into a minute description of the disease, I shall only endeavour to give a general view of its nature and effects, in each of those years; from which it will appear how widely the infection of one differed from that of the other. About the middle of March 1742, the smallpox broke out in Mahon, to the great consternation of the natives, who had not seen them since the year 1725, but well remembered the destruction which they then occasioned. The contagion quickly spread about, and was soon conveyed to the other towns and villages; insomuch that before the end of April it prevailed in every part of the island. As it attacked almost all who were under seventeen, and many of a more advanced age, the sick were so numerous during May and June, that every house might be called an hospital. About the end of July the dis- ease suddenly disappeared, most of those who were susceptible of it having by that time undergone it. During the first six or eight weeks the distemper was favourable, and seldom proved fatal: but its virulence increased with the heat of the weather; so OF THE SMALLPOX. 175 that in June and July it was not uncommon, both at Mahon and Ciudadella, to bury ten or twelve of a day. Nevertheless, in proportion to the numbers, not many died"; and what mortality there was, hap- pened chiefly among children at the breast and the common soldiers. Among such multitudes of sick, all the different species of smallpox, described by authors, were sometimes met with: but both the distinct and con- fluent had a nearer resemblance to what Sydenham calls the anomalous, than to the regular smallpox. For though the fluxed kind commonly appeared on the second or third day, it was often the fourteenth or seventeenth before the roughness to the touch showed that those on the face began to turn; and on the legs and arms they frequently continued fresh till near the thirtieth. In these kinds of smallpox the secondary fever raged violently between the fourteenth and twenty-fourth day; and almost all who perished by the disease died on one or other of the intermediate days. The constancy of nature in promoting one or other of the common evacuations, whereby part of the morbid matter was discharged, contributed to save great numbers; for a plentiful salivation commonly appeared with the eruption, and continued till the suppuration was completed, not only in adults, but in those of all ages; even in children at the breast, whose want of sense to spit freely, was probably the chief cause of their suffering more than others. About the seventh day or sooner the swelling of the face came on; and it was regularly succeeded by a tumefaction of the hands, and sometimes of the !76 OF THE SMALLPOX. feet. But it was most remarkable in this epidemical smallpox, that a moderate looseness commonly ap- peared, as the pustules began to dry, and continued till the skin was in some measure cleared of the thick black crust that covered it; by which means the defect of perspiration was supplied, the symp- toms of the secondary fever were restrained, and many people were happily rescued from the jaws of death: whence we may learn, how reasonable it is to give purgatives in this stage of the disease, ac- cording to the rules laid down for that purpose by Drs. Friend and Mead. In December, 1745, the smallpox were brought from Constantinople by one of his majesty's ships, and the following year made a slow but fatal pro- gress over the whole island. During the spring of 1746, they confined themselves to^St. Philip's Cas- tle, without reaching Mahon, though they are but two small miles asunder. In the summer and autumn they were frequent in Mahon and the neighbouring parts. Then they travelled northward to Ciudadella, and disappeared in the spring; having carried off almost all the children who survived the chincough and summer fevers of the year 1746. It was how- ever very remarkable, that the longer the infection continued in the island, the milder it became; so that there was much less mortality in the northern, parts than in the southern, where it first broke out. Whilst the distemper raged at St. Philip's Castle, as I lived at Mahon, I saw but few of the sick; but I was informed by the physicians who attended them, that the pustules were commonly of the con- fluent kind, and often intermixed with purples; that OF THE SMALLPOX. 177 they seldom rose or filled well, but continued either hard like tubercles, or quite empty, or had a small quantity of ichor, with a black spot in their middle, and frequently seemed to wither before they were ripe; that the fever, instead of going off with the eruption, increased as the disease advanced, being generally accompanied with a coma, delirium, diffi- culty of breathing, incessant vomiting and loathing of food; that the face seldom or never swelled, but about the time that this ought to have happened, a soreness of the mouth or throat gave great uneasi- ness, the skin separated from the inside of the lips, and the breath became very fetid; that three fourths of the infected, in spite of all that could be contrived for their preservation, perished between the sixth and the fourteenth days of the fever. And the most of those who survived remained blind, consumptive, or lame with caries of the bones, sordid ulcers, &c. so that this disease approached nearest to the plague of all which had been known in the island. From those accounts (which were too well con- firmed by my own experience afterwards) I conjec- tured, that the extraordinary mortality of the dis- ease was owing, partly to the variolous matter abounding so much in the blood, that the skm was not capable of receiving the whole quantity; partly to the peculiar disposition of the air at that time, ' which, as we have seen in the former chapter, rem- dered the head and breast extremely liable to in- flammations. Hence I imagined that many of the sick died of a phrenitis or peripneumonia, on the sixth, seventh, or eighth day, before the pustules had time to ripen; while in others, the pustules having 178 OF THE SMALLPOX. terminated in a gangrene, the corrosive ichor re- ceived into the blood proved fatal about the end of the second week. It appeared to me that the most probable way of averting those disasters would be, to make large evacuations in the first days of the distemper, and to replenish the vessels with mild antiputrescent liquors; by which means, either the eruption would be prevented, or the pustules would be fewer in number; or at least disposed to suppu- rate rather than mortify. This method of treating the smallpox is countenanced by Ballonius, (Ephem. & Epid. 1. i.) and strongly recommended by Boer- haave, (Aph. 1393.) who probably took the first hint from Rhazis;* and if ever so bold a practice could be justified, it was in such a pestilential kind as this, which destroyed almost all who were left to nature, or managed in the common way. These con- siderations, and the visible good effects of bleeding and purging largely in the predominant pleurisies, gave just cause to expect some benefit from a simi- lar method in the cure of the smallpox; which ap- prehension was confirmed by the following accident. A young man, about twenty-six years of age, was seized on Wednesday, May 21, between seven and eight o'clock in the morning, with a coldness and shivering, which was soon succeeded by common feverish complaints, and a pain under his left breast, straitening respiration. On Thursday morning, when * Si antequam apparere incipiant variolae, jegrum medicus inveniat, minuatur sanguinis multitudo—Venter autem si strictus fuerit, infusiones quotidie in potu sumantur, ex hoc enim aut omnino prohibebitur pustularum egressio, aut si quid egressum fuerit, parvum erit. Vid. Op. Venet. de Febr. cap. xviii. p. 10*. OF THE SMALLPOX. 179 I first visited him, imagining the case to be a pleu- risy, I ordered him to be treated accordingly. In consequence of which seventeen ounces of blood were taken away immediately; twenty ounces more in the afternoon, and fifteen on Friday morning; his belly was kept open by clysters; his drink was bar- ley water, to which oxymel and nitre were added; and sometimes a decoction of tamarinds; and leaves of the opuntia were frequently applied to his side. On Friday forenoon his pains were easier: but he complained greatly of an inclination to vomit, and after drinking warm water threw up a considerable quantity of bilious matter. In the afternoon an eruption was discovered all over his body, which, from the appearance of it on his face, and its being attended with a ptyalism, I suspected to be the confluent smallpox; and Dr. Segui, an eminent physician of Mahon, who was consulted on this emergency, confirmed my opinion. Our patient was blooded thirteen ounces on Friday evening; and afterwards drank plenty of warm water, in order to carry off his vomiting; a clyster was like- wise injected, his head shaved, his whole skin clean- ed and washed. On Saturday morning the fever being moderate, and the eruption thick all over him, he took a mild purge, which procured six or seven stools, and a grain of opium was given at bed time. On Sunday morning, after a restless disturbed night, his spitting having ceased, he complained of his throat being so sore that he could scarce swallow, and that the stitch had moved from his left breast, and fixed about the lower ribs in the right side. These symptoms induced us to bleed him a fifth time, to the quantity of eleven ounces, which were 180 OF THE SMALLPOX. of a crimson colour, as all the rest of his blood had been, without any sizy crust. In the afternoon he spit considerably, slept sound, was free from pain; and after a good night's rest, on Monday morning his purge was repeated, which gave six or seven motions, without checking the salivation. After this all far- ther evacuations were laid aside (except clysters to keep the belly open); the pustules, which were small and numerous all over him, began to fill with good matter, and every thing went on according to our wish. On Tuesday morning his face swelled; but abated on Thursday afternoon, the pustules begin- ning to dry; while his right foot swelled, and be- came painful, the ptyalism still continuing. Monday morning, June 2, his skin being dry every where, he took physic, which was repeated on the Friday fol- lowing. He soon gained strength, and still enjoys a good state of health. The next patient whom I attended in this dis- temper was a Jew's daughter, about five years of age, to whom I was called on Saturday morning, May 24, when the pustules were just beginning to appear, she having been feverish since Wednesday morning. She was thrice blooded by my order, in the space of twenty-four hours; four ounces being taken away each time, she was strictly kept to the cooling regimen; clysters were frequently inject- ed; and she commonly took a paregoric at night. The pustules were low, small, confluent, and attend- ed with a considerable salivation. Her face swelled on Tuesday, her hands the day following, and her feet on Friday. On Sunday, June 1, the pustules began to dry on her face. On Monday she was OF THE SMALLPOX. 181 purged, and gradually grew strong. This and the former patient were the first two in Mahon, who at that time recovered of the smallpox. About the end of May, and the beginning of June, three or four adults were attacked with violent feverish symptoms; and as they never had the smallpox, it was suspected that they had catched the infection. They were all treated in the same manner with the man, whose case has been already related, and in six or seven days got perfectly well without signs of eruption. Nor did any of them take the smallpox afterwards. («) Elevated with this success I began to flatter my- self that I had now hit upon a method of cure which would generally answer: but it was not long before experience convinced me of my mistake. A young man, about twenty-one, was seized at noon, Monday, June 16, with feverish symptoms, and a violent pain in his stomach, loins, and left breast. He lost fifteen ounces of blood on Tuesday morning, seventeen ounces the same afternoon, and fifteen on Wednesday morning. All this day he was sick and squeamish, though he drank much warm water, and vomited up bile along with it. He passed an uneasy night, with great pain at his stomach and (a) The same remedies have lessened the eruption where they have not annihilated the smallpox. It was from observing these effects of those remedies that Dr. Boerhaave and Dr. Hillary supposed a specific existed which would destroy the virus of that disease in the same manner that mercury is sup- posed to destroy the virus of the venereal disease. For awhile the same medicine was supposed to act in that way in preparing the body for the smallpox by inoculation, but from similar ad- vantages having attended the use of purges and other evacua- tions, it appears that the mercury acts upon the body in a man- ner equally, mechanical. -,_,. 182 OF THE SMALLPOX. in the small of his back, and on Thursday morning took a mild purgative, which operated-several times upwards, and procured six or seven stools. On Fri- day morning the smallpox began to appear in his face; his stomach was somewhat relieved, but the pain in his back continued as bad as ever; his mouth and throat were very sore; and I was informed that he had been delirious all night. Twelve ounces of blood were drawn, which was red and florid, like all the rest which had been taken. In the afternoon the pain of his back being severe, the part was cupped and scarified, and a clyster was injected, which brought away much hard stinking excrement. Not- withstanding this he got no relief; the raving, vo- miting, and restlessness increased, the pustules never filled, his mouth was ulcerated, and his breath be- came offensive to the smell. On Sunday morning he lay quite stupified and senseless; black spots ap- peared in the middle of the pustules; and he ex- pired that day about noon. Upon opening the body nothing extraordinary was found, except a monstrous large gall bladder full of thick, green bile, and slight signs of inflammation in the villous coat of the sto- mach, the small guts, and pia mater. (F) A young lad of fifteen or sixteen years felt some difficulty of breathing, and a pain in his back on Tuesday noon, June 24. He concealed his illness to Thursday, when he complained much of heat, thirst, and headach, sickness at his stomach, and a painful oppression on both sides of the thorax. Eleven ounces of blood were taken on Thursday morning, (b) It would seem from the morbid state of the gall bladder and stomach, which occurred in the above case, that even the smallpox in Minorca partook of the bilious endemic of the island. OF THE SMALLPOX. 183 eight ounces that afternoon, and ten next morning; clysters and diluent drinks were used, &c. None of his blood appeared sizy; and before the last ten ounces were taken, something like the smallpox were seen on his face. But the eruption never advanced; and on Saturday morning purples came out all over him. He then began to use the bark every two hours, and took in all about six or seven drachms. In the mean time he was very delirious, vomited often, and breathed with great difficulty. On Monday morning he was seized with a hemorrhage from the nose, which continued till seven at night, when he died with black spots all over him. Soon after this a robust middle-aged man fell sick, and was treated in the same way; on the second and third days of the disease he lost forty-nine ounces of blood; on the third day the eruption began to ap- pear; on the fourth he bled some spoonfuls from the nose; and purple spots broke out all over him. The smallpox never rose; he raved incessantly, though he was afterwards twice blooded, and had blisters applied. He died on the eleventh day. (c) These unfortunate cases made me lay aside large evacuations for the future, and content myself with endeavouring to alleviate the symptoms in the com- (c) The editor suspects the author was restrained from bleed- ing as much as these two cases required, by the presence of petechia:, and by the blood not putting on a sizy appearance. Hundreds have perished from the petechia being supposed to mark a putrid, instead of a highly inflammatory disease, and thousands have perished from an ignorance that there are seve- ral states of fever which indicate a higher and more dangerous grade of disease than sizy blood, and in which the lancet has been laid aside. That more bleeding was indicated in the two last instances is evident from the hemorrhages from the nose, which took place in eachofthem. __^^^^^^^^^^^^ 184 OF THE SMALLPOX. mon way, by moderate bleeding, blistering, anodynes, bark, and cordials, according as they were indicated. But in spite of all my attempts to cure them, more perished than recovered. Nor could I find that any other practitioner had better success, until time had corrected the malignity of the disease. In short, this epidemical smallpox sufficiently verified the English proverb, " That there is one sort in which the nurse cannot kill, and another which the physician can never cure." And since it is a matter of mere chance, whether the best or the worst kind is got in the natural way, it is evident what great honour is due to the memory of those gentlemen who first in- troduced the practice of inoculation into this king- do^, where the safety and security of it has been confirmed by the experience of thirty years. This is all that I have to offer to the public with regard to some of the most destructive distempers incident to mankind, whose nature and effects my situation afforded many opportunities of observing. I have related the failure as well as the success of my endeavours to cure them, with that fidelity required in affairs which so netrly concern the lives of our fellow creatures; and if these pages should be found serviceable to others, by pointing out what will prove hurtful or beneficial in similar cases, I shall not only think the pains which they cost me well bestowed, but esteem it a singular happiness that fortune put it in my power to contribute so far to the welfare of society. Hoc opus, hoc studium, parvi properemus et ampli, Si patriae volumus, si nobis vivere cari. Hon. FINIS. v. >\ /"led. Hist \jz XI0 CC24o \%\2 c. I ^'• ■■*■■ *"**:-v- *w;.5'-'-T'■■■■ ■ '*:■ ■.'-■.■■-'-I? #" &J