* < < < '*/'«. ___■ *. *»s& A SYSTEM O F SURGERY. EXTRACTED FROM THE WORKS OF BENJAMIN BELL, of Edinburgh By NICHOLAS B. WATERS, M. D. FELLOW OF THE COLLEGE OF PHYSICIANS OF PHILADELPHlAj AND ONE OF THE PHYSICIANS AND SURGEONS TO THE PHILADELPHIA DISPENSARY. ILLUSTRATED with NOTES and COPPER-PLATES. -----------------'■■"BiS.'illl SECOND EDITION. PHILADELPHIA: PRINTED BY BUDD & BARTRAM, FOR THOMAS DOBSON, AT THE STONE-HOUSE, N° 41, SOUTH SECOND-STREET, l802. No. 21. Diilricl. of Pennfylvania, to wit : BE it remembered, that on the nineteenth dey ef Atiguft, in the fixteenth year of the Independence of the United States of America, Tho- mas Dobfon, of the faid diftrid, hath depofited in this office the title of a Book, the right whereof he claims, as proprietor, in the words follow- ingj to wit: " A Syftem of "Surgery, extracted from the Works of Benjamin Bell, " of Edinburgh: by Nicholas B. Waters, M. D. Fellow of the College " of Phyficians of Philadelphia, and one of the Phyficians and Surge- " ons to the Philadelphia Difpenfary.—Illuftrated with Notes and Cop- " per-pia.tes." In conformity to the aft of the Congrefs of the United States, intituled, " An a<5t for the encouragement of learning by fe- curing the copies of Maps, Charts, and Books, to the Authors and Pro- prietors of fuch copies, during the times therein mentioned." SAMUEL CALDWELL, Clerk of the Diftricl of Pennfylvania. PREFACE. SURGERY teaches us the knowledge of all thofe difeafes which require manual operations for their removal; their caufes •, and the methods of preventing and of curing them. For fome years part it has been a fubjedr. of regret with the medical part of the public, and particularly among •ftudents, that we have had no work on this important branch of medicine, which gives a view of the prefent ftate of the art, in a moderate compafs: Mr. Bell's fyf- tem, although a mod valuable production, being extend- ed to fb great a length, as to be not only expenfive, but exceedingly inconvenient. To fupply this defecl, I have repeatedly heard a wifh expreflcd, by fame of the mod eminent cf the profeflion, that a felection of the more eflential parts of Mr. Bell's treatife were made; in which, however, nothing ufefpl, immediately relating to Surgery, Ihould be omitted. Although well aware that I might not execute a work of this kind in fuch a way as to Obtain the approbation of the critical reader, yet the belief, however miftaken, that it might be done by any perfon tolerably acquainted with the fubjecl, If not in the beft manner with refpeft to lan- guage, aj leaft in fuch a manner as to be highly ufeful; the late Dr. Jones, formerly profeflbr of furgery in King's College, New-York, cheerfully engaging to look over the manufcript, and add occafional obfervations,* furniflied by his own experience; Dr. William Shippen, profeflbr of anatomy and furgery, alfo obligingly promifing to de- vote * Thefe will be readily diftinguifhed from fuch as I have given myfelf, which confift chiefly in extracts from different authors of merit. IV PREFACE. rote a part of his leifure to the perufal of the work; I de- termined to rifk the undertaking. How far I have fuc- ceeded in the attempt, mult be left to the decifion of my medical brethren. Thofe who cannot readily conceive that the eflential parts of a performance of {even volumes can be comprifed in a fingle one of the fame fize, will pleafe to confider, that J this one volume, from the manner in which it is printed, contains at leaf! as much as any two of the original •, and that the anatomical defcriptions, defcriptions of operations and practices which are, at prefent, feldom if ever employ- _ ed, theoretical difcuflions, and repetitions, which, taken together, occupy no fmall part in the work of Mr. Bell, are entirely omitted. As Mr. Bell exprefles his opinion fomewhat differently, on the fame fubjecf, in different places, I may fometimes appear to have juftly incurred the cenfure of mifreprefenta- tion; but I beg that in fuch inftances, a judgment may not be formed without a previous attention to every thing that is delivered on the fabjedl in queftion. Following the general plan of the original treatife, I have attempted no fyftematic arrangement of the difeafes to be confidered ; becaufe thefe have feldom much con- nection in their general fymptoms, or in their refpedtive modes of cure. When, indeed, the different fubjedts ap- peared to be conne&ed, or illuftrative of each other, they are generally treated of in immediate fucceflion. After noticing the appearance or fymptoms of the dif- eafe, its ufual and known caufes are confidered; its pro- bable confequences; and the beft method of treatment: And when an operation of importance is defcribed, the parts which fhould be avoided, as well as thofe that are to be divided, are particularly pointed out. CONTENTS. CHAP. I. Page. Of Inflammation and its Confequences, i CHAP. II. On the Theory and Treatment of Ulcers, 17 CHAP. III. Obfervations on White Szuellings of the Joints, 66 CHAP. IV. Of Sutures, 74 CHAP. V. Of the Ligature of Arteries, and other artificial means of stopping Hemorrhagies, 79 CHAP. VI. Of Blood-letting, 84 CHAP. VII. Of Aneurifms, 100 CHAP. VIII. Of Hernia, 115 CHAP. IX. Of Hydrocele, 134 CHAP. X. Of the Hematocele, 151 CHAP. XL Of the Varicocele, Cirfocele, Spermatocele, and Pneumatocele, 154 CHAP. XII. Of the Sarcocele, or Schirrous Testicle, 156 CHAP. XIII. Of Difeafes of the Penis, 161 CHAP. vi CONTENTS. CHAP. XIV. Pajje. Of the Stone, 166 CHAP. XV. Of Incontinence of Urine, 187 CHAP. XVI. Of a Supprefifion of Urine, 189 CHAP. XVII. Of Obstruclions in the Urethra, 192 CHAP. XVIII. Of the Fistula in the Perinaum, 198 CHAP. XIX. Of the Hemorrhois or Piles, 202 CHAP. XX. Of Condylomata, and other finiilar Excrefcences about the Anus, 204 CHAP. XXI. Of a Prolapfus Ani, 206 CHAP. XXII. Of an Imperforated Anus, 207 CHAP. XXIII. Of the Fistula in Ano, 209 CHAP. XXIV. Of the Paracentefts of the Abdomen, 2I5 CHAP. XXV. Of the Paracentefts of the Thorax, 219 CHAP. XXVI. Of Bronchotomy, 228 CHAP. XXVII. Of Oefophagotomy, 230 CHAP. XXVIII. Of the Amputation of Cancerous Mamma, 233 C H A P. CONTENTS. ?it CHAP. XXIX. Page. Of Affeclions of the Brain from external Vio- lence, 235 CHAP. XXX. Of Difeafes of the Eyes, 257 CHAP. XXXI. Of Difeafes of the Nofe and Fauces, 304 CHAP. XXXII. Of Difeafes of the Lips, 318 CHAP. XXXIII. Of Difeafes of the Mouth, 324 CHAP. XXXIV. Of Difeafes of the Ears, and Operations prac- tifed upon them, 354 CHAP. XXXV. Of the Wry-Neck, 360 CHAP. XXXVI. Of Difeafes of the Nipples, 361 CHAP. XXXVII. Of Ififues, 362 CHAP. XXXVIII. Of the Inoculation of the Small-Pox, 364 CHAP. XXXIX. Of Wounds, 365 C H A P. XL. Of Burns, 41 *: CHAP. XLI. Of Tumors, 420 CHAP. XLII. Of Fraclures, 464 CHAP. viii CONTENTS. CHAP. XLIII. Of Luxations, CHAP. XLIV. Page 494 Of Distorted Limbs, CHAP. XLV. 521 Of Distortions of the Spine, CHAP. XL VI. 524 Of Amputation, CHAP. XLVII. 527 Of removing the Ends of Bones, in Difeafes of the Joints, CHAP. XLVIII. 554 Of preventing or diminithing Pain in Chirurgi-cal Operations, CHAP. XLIX. 557 Of Midwifery, CHAP. L. 558 Of opening Dead Bodies, CHAP. LI. 5^3 Of Embalming, CHAP. LII. 5^5 Of Bandages, 5fy A SYSTEM of SURGERY. C H A P. I. 1 i' iKMHi i "" On Inflammation and its ConfequenccS. S E C T I O N I. Of the Symptoms, Terminations, and Caufes of Inflammation. EVERY organized part of the body is liable to in- flammation -, but as the treatment of this affection, when feated in the internal parts, belongs to the province of medicine ; we propofe in this place, merely to confider the complaint, with Its confequences,as it is moll frequent- ly obferved to occur externally. And as the greater part of the phenomena which in general attend it, will be underftood from the confideration of Phlegmon, we fhall confine our obfervations more particularly to that fpecies of the difeafe. Phlegmon is a circumfcribed tumor, attended with heat, rednefs, tenfion, and a throbbing pain •, and, if ex- tenfive, with fever. When thefe fymptoms are removed, and leave the part lanaltered in its flruclure, the difeafe is faid to terminate by refolution. If however, in a fhort time all the fymptoms are aug- mented, and the tumor becomes foft, fomewhat prominent A iq [ 2 ] in the middle, or towards the mofl depending part, ac- quires'a clear, fbining appearance, and becomes lefs pain- ful ; the different fymptoms of fever then abate, and upon preffure a fluctuation is perceived ; the inflammation is then faid to end in fuppuration. But if all the fymptoms, general as well as topical, ex- cept the fwelling, continue to increafe, there will be reafon to apprehend that gangrene will foon take place. Gangrene, or mortification, is firft indicated by a change of colour in the part affected, from a bright red to a livid or leaden caff, while fmall veficles, containing a thin acrid ferum, are difperfed over its furface—the pain abates and the pulfe finks—but continues frequent—the tumor at laff lofes its tenfenefs—turns black and flaccid—and the part is entirely deprived of its vital properties. Thefe are the mofl common terminations of inflamma- tion ; but fometimes, though very rarely, it ends in fchir- rus, The general exciting caufes of inflammation, are what- ever tend to produce irritation and pain. They are either external or internal. The external caufes are, wounds of all kinds; bruifes; burns, whether by the actual or po- tential cautery; corrofive and ftimulating applications, as flrong acids, cantharides, and rubefacients 5 ligatures, and tumors that act as ligatures ; violent exercife of a particu- lar part; and cold partially applied. The internal caufes are morbid matters of various kinds; as thofe of fyphilis, fmall-pox, meafles, fcrophula, and fevers. Thofe circumftances which feem to give a predifpofition to inflammation are, a full plethoric habit of body, indu- ced by a very nourifhing diet, or by want of exercife; or perhaps by a combination of both—Inflammation occur. alfo more frequently in young than in old people, and in men than in women. The proximate caufe of inflammation feems to confift in an incrcafed action of the arteries of the part; and when the I 3 3 the difeafe does not originate from the application of irri- tating fubflances, this, as well as the increafed action of the heart when it occurs, feems to be fupported by a fpafm or conflridtion of the extreme veffels, either of the parti- cular part or of the general fyflem. See Cullens Praft. Phy/ic. vol. I. In almoft every cafe of external inflammation, the prog- noftick may be favourable. For if refolution, which is the eaiieft, and molt defirable mode of termination, is not ef- fected, fuppuration will mofl readily be the confequence; and the danger attending that, if the conflitution is other- wife healthy, is feldom great:—When, however, the dif- eafe is extenfive, and the fymptoms very violent, there is much danger to be feared; for, independent of the rifk from the fever itfelf, if the fymptoms continue high for any length of time, without fhewing a tendency to refolution or fuppuration, gangrene will pretty certainly follow : and in what manner that may terminate is always uncertain. SECT. II. Of the Treatment of Inflammation by Refolution. In the cure of phlegmon, the firfl indication in general is to promote refolution. There are, however, fome cafes in which this is not to be attempted. Thus inflammato- ry fwellings, that fucceed to fevers, and other internal dis- orders, fhould always be brought to fuppurate as early as poffible: as it is generally fuppofed, that nature by thefe points out an outlet for fome fuperabundancy of fluids; and that it might be attended with danger to give her any interruption. And in phlegmons occurring in fcrophula, we fhould trufl entirely to the operations of nature; for if they are repelled, bad confequences might enfue; and if brought to fuppuration they produce fores very trouble- fome to heal. In _ 4 .1 In cafes of incipient phlegmon, where the general fyf- tem is not affected, topical remedies merely, with a pro- per attention to regimen, will often accomplifb a refolution. But when the effects of the difeafe are in any confiderable degree extended to the whole fyfiem, it becomes neceffary at the fame time to pay attention to thefe. The firfl circumftance to be attended to in every cafe, is the removal of all exciting caufes that continue to ope- rate. Of applications to the part, thofe of a fedative nature are chiefly to be depended on; and next to thefe, emol- lients. Of the former may be confidered the preparations of lead diffolved in vinegar, and the vegetable acid. Of the latter, all the bland expreffed oils, alone, or joined with wax, in form of a foft ointment. With refpect to fedative applications, it is not meant to recommend the whole clafs in external inflammation. Thus opium, one of the mofl powerful fedatives, when applied externally, always produces fome degree of irri- tation ; and although it perhaps may have been very ufe- ful in fome fpecies of inflammation', yet it will probably never become of general ufe in fuch difeafes. Warm emollient fomentations too, although more powerful, as fedatives, in removing tenfion and pain, than any other remedy; yet from experience, I am well con- vinced they always tend to produce fuppuration; and when this is not occafioned, they leave fuch a relaxation in the parts, as renders the complete removal of the dif- eafe exceedingly tedious. Similar objections may be made to mofl fedative ap- plications. They do not, however, operate againft the ufe of the preparations of lead; which we may affirm, from the experience of a great many practitioners, to be by far the mofl ferviceable remedies as difcutients, that have yet come into general ufe. They have been faid to produce deleterious effects in fome inflances; but thefe have been very [ 5 ] very rare; and I have known the greater part of the fur- face of the body to be covered with them for weeks, with- out any bad confequences being occafioned by them. Saccharum faturni, or the fugar of lead, as being the preparation whofe flrength can be mofl exactly afcertained, fhould be preferred to any of the others. It is mofl conveniently applied in the form of a watery folution; for the preparation of which the following proportions in general anfwer very well: R. Sacch. Saturn. |fs folve in aceti §iv\ & adde aq. fontis diflillat. tbij. The addition of vinegar renders the folution more complete. Mr. Goulard's vegeto-mineral water is preferred by fome to this preparation: it is made by adding two tea fpoonfuis of the Extraclum Saturni to a quart of water, and four tea fpoonfuis of brandy. The quantity of extract or brandy to be diminifhed or increafed accord- ing to the nature of the difeafe, or fenfibility of the part. Cataplafms made of thefe preparations and crumb of bread, fhould be conftantly applied, as cold as the patient can bear them without uneafmefs, and be renewed when- ever they become hard. When the inflamed part is not ve- ry tender, or lies deep, the vegetable acid inftead of the lead anfwers very well; and an alternate ufe of this and the lead has, in fome inflances, appeared to be more ferviceable than a continuance of cither feparately. If, however, the fenfibility of the part does not admit of poultices, doubled pieces of foft linen, moiitened with the faturnine folution, fhould be fubflituted to them. Emollients tend greatly to remove inflammation : but as they are lefs efficacious than the preparations of lead, and always blunt the action of thefe, they fhould never be employed except the tenfion, irritation, and pain are very confiderable: when any o? the mild expreffed oils may be gently rubbed over the inflamed parts two or three times a-day. Topical [ 6 ] Topical bleeding fhould always be employed when the inflammation is extenfive: and the blood fhould be drawn from a part as near as poffible to the difeafe. Refl fhould be enjoined—and the ufe of animal food, and of fpirituous and fermented liquors, ftrictly forbid. And, When a confiderable degree of fever comes on, it will be proper to order general bleeding, gentle laxatives, and cooling diaphoretics. We fhould then procure eafe to the patient by the exhibition of opium in large dofes. By thefe means, in the courfe of a few days, refolution of the tumor will gently begin to take place. The fame plan fhould then be purfued, but with caution; be- caufe, if fuppuration fhould at lafl be produced, its pro- grefs will be rendered flow and uncertain by debilitating the fyflem, and the patient will not be capable of fupport- ing the confequent difcharge, fliould it be confiderable. Although we may generally determine, in the courfe of three or four days, whether the difeafe will end in refolution or not •, yet it muft be obferved, that inflam- mations in tough membranous parts, often continue a confiderable time without fhewing any tendency to ter- mination : In fuch cafes, we fhould never be deterred from a perfeverance in the ufe of refolvents, unlefs the fymp- toms of fuppuration commence, gangrene is threatened, or an incurable obflruction is feared ; when fuppuration fhould always be encouraged as much as poffible. SECT. III. Of Suppuration. Suppuration is that procefs by which the con- tents of tumors and ulcers are converted into a whitifh, thick, ■ [?] thick, opaque, and fomewhat foetid matter, termed Pus. This, by many, has been fuppofed to be effected entirely by a natural exertion of the fyltem; but experience teach- es us, that art is capable, in all cafes, of giving confider- able afliflance. With refpect to the formation of pus, various opini- ons have been entertained. By fome, pus has been be- lieved to confift in a diflblution of the blood-veflels, nerves, and other folids, in the fluids of inflamed parts. Others, have fuppofed it to be formed in the blood •, and that it is from thence fecreted into abfceffes, wounds, and ulcers. But the mofl probable opinion is, that pus is produced by a certain degree of fermentation upon the ferous part of the blood, after its feparation into the ca- vities of ulcers and abfceffes; and this, in confequence of the natural heat of the part, or of heat artificially appli- ed. And it is further rendered probable by experiment, that as the ferum is depofited more or lefs free from fat, red globules, &c. it will yield a pus more or lefs pure or vitiated. Vide Cullen and Pringle. When fuppuration is to be promoted, all the means of producing refolution mufl be laid afide. But as a certain degree of inflammation is found neceflary for the forma- tion of pus, it will be improper to let the inflammatory ftate fubfide fuddenly. The diet of the patient fhould there- fore be regulated by the circumflances of phlogiflic diathe- fis,or of debility which feem to prevail; and, fuch applica- tions fhould be made to the inflamed parts as tend to pre- ferve in them a proper degree of heat. This lafl is a cir- cumflance of the utmofl importance—And the experi- ments of Mr. Gaber and myfelf on ferum out of the body, and of myfelf on inflammatory tumors in the body, have made it evident to me, that the greater the heat is, to a certain extent, the fooner fuppuration will take place. From hence it probably happens, that fwellings near the heart fuppurate in much lefs time than thofe more diflant from C 8 ] from it; and the want of a due degree of heat, perhaps, prevents the greater part of foft fwellings from coming to fuppuration-, which then form atheromata, fleatomata, and melicerides. Warm fomentations and cataplafms are the means generally ufed for the application of heat to phleg- mons : and when they are frequently renewed, they anfwer the purpofe very effectually. But if they are not applied more than once or twice a-day, it is probable they do more injury than good. For as foon as the heat they at firfl poffefled is diffipated, the moifture they fup- port, with the confequent evaporation, mufl always ren- der the part colder than if it had been merely wrapped up in flannels. In order to receive advantage from thefe remedies, the parts affected fhould be well fomented with flannels, preffed out of fome emollient decoction, and applied, as warm as the patient can bear them, continued half an hour at once, and renewed four or five times a-day. Im- mediately after the fomentation, a large emollient poultice fhould be applied warm, and renewed every two or three hours. Bread and milk, with a little butter or oil, in common, forms the mofl eligible poultice. When there is a defect of inflammation in the tumor, roafted onions, garlic, &c. may be added to the poulti- ces •, but ftrained galbanum, or fome other of the warm gums, diffolved in the yolk of an egg, or a fmall portion of cantharides, are much more elegant and efficacious additions. Plafters of the warm gums are ufeful, and become neceffary fubftitutes to the poultices, if the patient cannot be confined within doors. Dry cupping, i. e. cupping without fcarification, upon or as near as poffible to the-affected part, in cafes where inflammation is defective, is alfo eminently ferviceable. Thefe - 9 1 Thefe applications mould be continued, until fuppiira-- tion takes place; which feldom fails to be the cafe, in a longer or fhorter time, according to the ckcumftan- ces of the difeafe—The formation of matter is indicated by a remiffion of all the fymptoms. The throbbing pain goes off, and a more dull and conflant pain fucceeds j the tumor becomes pointed at fome particular part, gene- rally near the middle, where, if the matter is not contained in a cyfl, or very deep-feated, a whitifh-yellow appear- ance is obferved ; and a fluctuation of fluid is plainly per- ceived upon preffure. In addition to thefe local fymptoms, whenever a large collection of pus is formed, frequent fhiverings almoft conftantly occur. In the treatment of collections of matter or abscesses, it is a general rule never to open them, until a tho- rough fuppuration has taken place ; for if it is done be- fore, they never heal kindly. An exception to this rule occurs in the treatment of critical abfceffes that are pro- duced in malignant fevers, and in the plague—Thefe fhould be opened as foon as it can be afcertained that there is a depofition of fluid. And collections of matter/ on the joints, or over the cavities of the breafl or belly, efpecially if they run deep, ought to be difcharged as foon as any fluctuation can be perceived. Becaufe, when the refiflance on every fide is equal, they may as readily pour out their contents internally as externally ; and the confequence of a large abfcefs, burfting into either of the large cavities, is commonly fatal. Abfceffes have ufually been opened either by Caufk of Incifon. With refpect to the cauftic, it is not attended with any fuperior advantage to a fimple incifion : It gives much more pain; it is more flow in its effects; and it is impoffible always to confine its operation to thofe parts which were alone intended to be affected, On account B of of thefe inconveniencies, incilion with a lancet or fcalpel, is very generally preferred to it. When the fwellings are not very large, they are com- monly opened by an incifion, extending two-thirds of their length, and terminating at their lower extremity : but abfceffes of confiderable extent fhould be laid open their whole length. It has been advifed by fome, to take away a part of the teguments, when they are very much ftretch- ed; but this can very feldom be neceffary or proper— never indeed, unlefs the parts are completely dead. The inconveniencies of opening abfceffes with the knife, arife from the fuddennefs of the difcharge of their con- tents, and the admiflion of air to the ulcerated furface. The firft occafions faintings, and other difagreeable fymp- toms, and the latter often induces an aftonifhing change in the difcharge, from a well digefted pus to a thin fanies ; and that fometimes within fo fhort a fpace as forty-eight hours ; and afterwards, if the tumor has been very large, a hectic fever, which either proves fatal in a fhort time, or terminates in confirmed phthifis. It feems probable that the air produces thefe effects by its irritation ; by ftimu- lating the veffels to a greater abforption, and by rendering the matter to be taken up more putrid. None of thefe bad confequences of incifion and cauftic, follow the ufe of the feton. It therefore, with propriety, claims a preference to both of them. When the feton is employed in opening abfceffes, there is little or no furface of the lore expofed to the air; a gradual difcharge is occa- fioned ; it is attended with very little pain and inflamma- tion ; produces a very fmall cicatrix ; and generally com- pletes a cure in half the time neceffary to accomplifh it when incifion or cauftic are ufed. The feton is to be formed as follows :—An opening fufficiently large for the cord, being made with a lancet in the fuperior part of the abfeefs, a director, flightly curved, and having an eye at one end, threaded with a C » 1 a cord of candle-wick cotton, or of foft filk, pro- portioned in thicknefs to the fize of the tumor, is then to be introduced, and its point to be pufhed downwards until it is felt externally, exactly oppofite to the mofl de- pending part of the fwelling. The director being kept firm by an affiflant, an incifion is to be made with a fcal- pel upon its lower end, fomewhat larger* than the open- ing firfl made. The director is now to be withdrawn downwards, with fo much of the cord as will leave two or three inches of it hanging; out of the lower orifice. In about twenty-four hours after the introduction of the cord, and daily afterwards, fo much of it fhould be drawn downwards as will admit of all that part of it be- ing cut off which had been lodged in the abfcefs. In order to make the cord pafs eafily, the part to be ufed fhould always be rubbed with fome emollient ointment. By this method of cure, the gradual difcharge produced, admits a gradual contraction of the fides of the cavity, and the flight inflammation fupported on their furfaces, by the irritation of the cord, induces a firm and fpeedy union of them. As the difcharge diminifhes, the feton fhould be leffened by degrees, by withdrawing a thread of the cot- ton once in two or three days. At length, when little more matter is produced than may be fuppofed to arife from the irritation of the cord, it may be altogether taken out; and a gentle preffure fhould then be made on the parts by a roller, until the completion of the curef. Every * This will hinder an inconvenient tranfuding of matter above. B. f Several objections may be offered tp Mr. Bell's method of opening abfceffes with the feton : In the firft place, it does not appear to be an eafy matter to pafs a feton in the mode he directs, through a large or deep abfcefs, or that it fhould anfwer the purpofe he propofes by it. In the large deep abfceffes frequently formed in the brearts of fat women, fuch fmall openings do not difcharge the matter contained fufficiently to prevent new and troublefome fioufes; and many women are too timid to t »* 3 Every thing that has been faid refpecting the cure of abfceffes from recent inflammation, applies with equal pro- priety, to all tumors which contain a purulent matter, or a fluid not much thicker than pus, SECT. IV, Of Mortification, A complete mortification, or the lafl ftage of gangrene*, is known by the difeafed part becoming black, by its lofing all pain and fenfation, and by its emitting a confiderable fetor.—A foftnefs, and entire diffohnion of the different parts of the organ affected, alfo in commmon take place. There is a fpecies of gangrene called the dry, in which the parts continue hard and connected a confiderable time although entirely mortified. This feems to be produced from an obflructed flow of blood to the parts, by the prek fure of tumors, ligatures, &c.; and is never a confequence of inflammation. With refpect to the difeafe termed the •white gangrene, and in which the parts preferve nearly the natural colour, it is very doubtful whether it can with propriety be confidered as a gangrene—We mean, in this place, to confine our remarks more particularly to that fpecies which fucceeds inflammation. They are, however, in general, applicable to all the varieties. Eryfipelasf is the fpecies of inflammation mofl apt to terminate to pernnt of one opening, inftead of two which muft be made by the fc ton-nor does frefh good air appear to be fo injurious to wounds as Mr" Edl feems to think Upon the whole, further experience feems neceffary before tins new mode c„n be generally preferred to that in common prac- tice. * * See what has been already faid on gangrene. f See fe>it. on inihznmatory tumort. t 13 ] terminate in gangrene; and when joined with phlegmon^ as it frequently is, it gives that the fame tendency. In fome inftances, mortification comes on almofl before an inflammation is completely formed. This occurs mofl frequently in carbuncles. In thefe, there is feldom any evident fwelling; and the parts often become gangrenous in the courfe of twenty-four hours. The rapid progrefs ufually made in thefe cafes renders them extremely dan- gerous, when very extenfive, or feated on any of the large blood veffels or nerves. If this is not the cafe, the patient frequently recovers, with the lofs of the affected part. Carbuncles commonly appear without any evident exter- nal caufe; and probably depend, in general, on a fcorbutic or putrefcent flate of the fluids. They are ufually a fymptom in peftilential difeafes ; but fometimes, although very rarely, they happen as idiopathic affections. Gangrene feems to be produced from a putrid fermen- tation in blood effufed by the violent action of the veffels in an inflamed part; and to be propagated, by the affimila- tory power of the gangrenous ferment. The feparation of the difeafed part is occafioned by an inflammation, and fucceeding fuppuration, of fome irritable part to which the mortification is extended; and the ge- neral fymptoms are readily accounted for from the debili- ty induced by the putrefcent flate of the fluids. See Cullen, Pr. Ph. vol. I. We fhould never make a pofitive prognoflic in the be- ginning of gangrene : for patients are fometimes Carried off fuddenly, without previoufly appearing in any imminent danger. When, however, the difeafe originates from ex- ternal inflammation, is not deep or extenfive, and has be- come flationary, the prognofis may generally be much more \ favourable than when it is produced from an internal caufe, is confiderable in extent, and continues to inereafe. For, in C 14 1 in this cafe, there is always the greatefl danger to be fear- ed ; and, even in any confiderable mortification from an external caufe, the patient cannot be pronounced free from danger until the entire feparation of the gangrened parts. As there have been many inflances in which death has fuddenly enfued after the ceffation of the progrefs of the difeafe, and before any general putrefcency has appeared, we conclude that the fatal termination is then produced, not from abforption of the putrid matter, as may be with probability fuppofed in long continued cafes, but from the deleterious effects of the gangrened part on the nervous fyflem. In the treatment of gangrene, whenever the general fymptoms of inflammation continue to a confiderable de- gree, it will be proper to order blood letting, laxatives, and acidulated cooling drinks. But evacuations, and particular- ly blood letting, fhould be ufed with the greatefl caution; and never to a greater degree than feems abfolutely necef- fary for moderating the violence of the fymptoms. When, however, as is mofl frequently the cafe if the difeafe has made any confiderable progrefs, the patient is much debilitated, the indication is, to give the fyflem fuf- ficient vigour to free itfelf from the mortified parts.* This is accomplifhed by a generous diet, and a liberal ufe of tonic cordials, and particularly of good wine. When very great debility and languor occur, volatile alkali, con- fectio cardiaca, &c. may be given with advantage. But of all the tonic remedies of mortification, the f common Peruvian * Mr. Pott defcribe3 a fpecies of mortification incident to the toes and feet, in which opium is a very effectual remedy, and nothing elfe is of any material benefit. B. \ Befides the advantages derived from the internal ufe of the bark, we may, from the experience of many practitioners in this city, with confi- dence recommend it as one of the moft powerful external applications in this formidable difeafe. C 15 _ Peruvian bark* is the mofl efficacious. It fhould be gi- ven as foon as the fymptoms of inflammation are abated, and in as large quantities as the flomach will bear—As a great irritability of this organ is very commonly a confe- quence of gangrene, it will be befl to exhibit the bark, ve- ry finely powdered, in combination with fome of the fpi- rituous waters. The vitriolic acid may alfo be given with advantage: and may be mixed with the patient's common drink. These are the internal remedies that can be with mofl: certainty depended on. There has been a great variety of external applications recommended; particularly all the warm gums and balfams, ardent fpirits, and even alcohol; and to admit of a nearer application of them to the found parts, deep fcarifications through the difeafed, and into the heal- thy parts, have conftantly been advifed. But it is proba- ble that thefe ftimulating fubftances, by exciting too flrong irritation, do more harm than good. And the in- cifions alfo may do material injury, not only by wound- ing blood veffels, nerves, tendons, &c. but alfo, by ad- mitting a free entrance of the putrefcent fluids into the found parts. For thefe reafons, and becaufe I have never known them productive of good effects, I have long been of opinion that they might be entirely laid afide.—Mr Pott concurs with me in fentiment,—It will, however, be proper to remove a portion of the mortified parts, when the difeafe is extenfive ; in order to leffen the fcetor, and contribute to render the healthy parts capable of throwing off the remainder : but the fcarifications fhould never ex- tend to the parts unaffected by the complaint. Theriaca * The red bark, from many experiments, appears evidently much ia- ferior to the common bark. B. [ 16 1 Theriaca has long been, and is now with fome, a ve- ry common application; but I never faw any evident good effects from its ufe. All the advantages to be derived from the common ap- plications in gangrene, are generally obtained with more eafc and certainty, from gently ftimulating embrocations. A weak folution of crude fal ammoniac in vinegar and wa- ter anfwers exceedingly well—a drachm of the fait to two ounces of vinegar and fix of water, form a mixture of a proper ftrength in common cafes ; but the degree of ftU mulus may be eafily increafed or diminiflied according to circumftances, by ufirrg a larger or fmaller proportion of the fait. When a flight inflammation commences on the verge of the living parts, we may generally with certainty ex- pect a feparation of thofe mortified: but after fuppura- tion is perceived, this, without doubt, will very foon follow- When the feparation is accomplifhed, the wound is to be treated as a fimple- purulent ulcer ; while at the fame time, proper attention is to be paid to the general ftate of the fyflem. It fometimes happens, that mortifications deftroy fo much of the foft parts in the extremities, that amputation becomes abfolutely neceffary. In thefe cafes, the opera- tion fhould never be performed until we are fatisfied that the progrefs of the difeafe has entirely ceafed. When this is determined, the limb fhould be removed as foon as poffible. See chap, on Amputation. CHAP. C 17 3 CHAP. II. On the Theory and Treatment of Ulcers. SECT. I. Obfervations on Ulcers in general. AN ulcer, is commonly defined a folution of continui- ty in any of the fofter parts of the body, difcharg- ing either pus, fanies, or any other vitiated matter. But it mull be evident, that every caries attended with lofs of fubftance might with propriety be termed an ulcer : how- ever, to avoid making diftinctions which are not abfolutely neceffary, we fhall confider caries as an accidental fymp- tom of ulcer, and treat of it under the general denomina- tion of carious ulcer. Ulcers have received various appellations, derived from their appearances, caufes, and other circumftances; but we fhall make fuch diftinctions only as appear to be of real ufe in directing the proper treatment. Ulcers may be divided into two general claffes. In the firft may be comprehended all thofe that are entirely local, and do not depend upon any diforder of the fyflem at large. In the fecond clafs all are included that are the confequence of, or that are connected with, any difeafe of the conftitution. The utility of fuch a claffification muft be evident from the difference of treatment neceffary in ac- complifhing the cure of the fpecies arranged under each divifion. Thofe of the firft clafs requiring none but to- pical remedies ; while in the latter, medicines that affect the whole fyftem are alfo abfolutely neceffary. C The Z i« 1 The topical ulcers are, i. The fimple purulent ulcer. 2. The fimple vitiated ulcer. 3. The fungous ulcer. 4. The finnous ulcer. 5. The callous ulcer. 6. The carious ulcer. 7. The cancerous, and 8. The cutaneous ulcer. The ulcers connected with an affection of the whole fyftem, are, 1. The venereal ulcer. 2. The fcorbutic, and 3. The fcrophulous ulcer. The general caufes of ulcers, are, 1. Occafional or ex- citing. 2. Predifpofing; or, 3. A combination of both thefe. Under the firft head may be ranked wounds in general— bruifes ending in fuppuration—burns—and inflammation which terminates in gangrene or fuppuration. The fecond divifion includes all fyftematical affections attended .with topical determinations; fuch as fevers that terminate in abfceffes—lues, fcrophula—and fcurvy. And, In the third, are comprehended the fores produced by a concurrence of the caufes above enumerated. Thus a Qight wound, in a habit contaminated by the abovemen- tioned difeafes, will occafion a troublefome fore, which, in a healthy conftitution would have healed without diffi- culty. • The prognofis in ulcers muft depend, 1. Upon their caufes. 2. Their fituation; and, 3. On the time of life and habit of body of the patient. The occafional caufe mufl evidently have a very confi- derable influence on the nature of the complaint, e. g. An ulcer produced by a wound inflicted with a fharp inftru- ment, will, every other circumftance being alike, heal much- more eafily, than one confequent to a bruife, or a wound from a ragged inftrument. Punctured wounds are likewife more difficult of cure than fuch as have large openings; this feems to originate, 1. From the want of a free exit to the matter; which, in confequence, caufes it to form finufes between the integuments and mufcles, &c. and [ 19 1 and, 2. To the pain and inflammation which fo particularly occur in wounds of this kind. 2dly. The fituation, whether with regard to the na- ture and organization of the parts affected, or their being feated on the trunk or extremities. Thus it has been long known that ulcers in the flefhy parts give lefs pain, afford a better-conditioned difcharge, and heal much more readily than thofe fituated on tendons, glands, the periofle- um or bones. And experience has taught us, that fores on the head and trunk heal much more eafily than thofe on the extremities, and particularly when the lower extre- mities are affected. This difference feems to arife principally from the de- pending fituation of the latter; for the fluids in the veins and lymphatics having here to proceed in a direction con- trary to their own gravity, and the former receiving but lit- tle aid'from the action of the heart; whenever any of the parts lofe their tone, or are deranged by accident, fwellitigs, and efpecially of the ferous kind, muft be produced. And when thefe fwellings arife in the vicinity of ulcers, by oc- cafioning too great an afflux of matter to the fore, they at length vitiate the difcharge, and thus protract the cure. The fituation of ulcers with refpect to the neighbour- hood of large blood veffels and nerves, or any of the larger joints or cavities, from the rifle of the matter penetrating to them, muft alfo confiderably influence the prognofis. And, laftly, The age and conftitution of the patient muft be taken into confideration. Thus, in young healthy peo- ple, ulcers will heal much more kindly than in the old and infirm. With refpect to the treatment of ulcers, the firft circum- flance to be determined is the propriety of attempting a cure or not. In recent fores there is no room for doubt; but when ulcers have been of long continuance, or appear to have had any- effect, either in carrying off or preventing difeafes C 20 ] difeafes to which the fyflem has formerly been fubject, it has always been confidered as dangerous to heal them ; and inftances have often happened of the fatal effects of the fudden floppage of long continued and large difchar- ges. From experience, however, we may now affirm, that the cure of any ulcer may be attempted, provided a difcharge of matter, equal in quantity to that produced by the ulcer, be kept up by any other means. This difcharge is mofl conveniently furniflied by an iffue. An iffue being introduced, and made to difcharge nearly as much as the ulcer, the cure of the latter may then fafe- ly be carried on ; and if the fore has not been of very long ftanding, thefize of the iffue may be gradually leffened, till it contains only a fingle pea; and it will then give but lit- tle trouble. But when the ulcer has been of long dura- tion, and particularly if it has apparently prevented any dangerous difeafe, the iffue fhould be continued of the fame fize for life. Its fituation may be determined by the conveniency of the patient. This circumftance obviates one objection that has been made to the practice, viz. that an iffue is as troublefome and difagreeable in its management as an ulcer ; for the fitua- tion of ulcers, independent of the nature of the difcharge they occafion, and of the bad effects of abforption of the matter on the fyftem at large, often renders them exceed- ingly inconvenient, and fometimes dangerous. It has been alfo objected to the fubflitution of a dif- charge by iffue to that by ulcers, that the matter produced is not fimilar ; that iffues conftantly afford a bland pus, while the difcharge from ulcers is often very acrid, and thus may free the fyftem from a matter highly pernicious to it. But that the effects of all thefe drains on the body at large, arife more from the quantity than the quality of the difcharge, is clearly evidenced by the following, as well as a variety of other circumftances, viz. that the fame bad I 21 ] bad effects are produced from the floppage of a difcharge from iffues, as from the healing of the worfl fpecies of ulcers. And it is very clear from many facts, that the variety of matter afforded by ulcers originates, except in fome cafes in which a great degree of putrefcency prevails, and the blood runs off in form of a thin ichor, from the degree of inflammation or peculiar conformation of the veffels in an ul- cerated part; from the heat fupported; and from the remora of the fluids for a longer or fhorter time in the ca- vity of the fore. Thus it cannot be proved, by any analyfis Gf the blood, that the acrid matter which is fometimes dif- charged, previoufly exifled in it; and by varying the degree of external heat, the applications to the fore, and the interval of the dreffings, we can vary the nature and appearance of the difcharge. SECT. II. On the fimple Purulent Ulcer. The fimple purulent ulcer, is entirely a topical affection, is attended by an inconfiderable degree of pain and inflam- mation, and affords a difcharge of mild pus. The granu- lations which arife in it are of a firm, red, healthy appear- ance, and if no accident occurs, in general, the cure goes on regularly until a cicatrix is produced. This ulcer is firft treated of, becaufe it is the mofl fim- ple that is produced, both in its fymptoms and method of cure. And, as it is to the ftate of fuch a fore that every other fpecies muft be reduced, before a cure can be ob- tained, we fhall be particularly minute in our obfervations with refpect to it; and, when treating of the other varieties of C 22 ] of ulcers, we fhall occafionally refer to what is here ad- vanced, in order to avoid repetition. The caufes of purulent ulcers, are, all wounds that do not unite without the formation of matter—burns, whe- ther produced by fire, aquafortis, fcalding liquids, &c.; bruifes ; and every external accident that terminates in fuppuration, with an opening as a confequence of it. The prognofis may generally be favourable; and more or lefs fo as there is a lefs or greater lofs of fubftance—fa- vourable or unfavourable fituation of the fore, and good or bad habit of body of the patient. Before proceeding to a particular inveftigation of the means to be employed in the cure of the fimple ulcer, it will be proper to make a few obfervations on the manner in which nature, as well as art, operates to accomplifh the healing of fores in general. In the progrefs of ulcers to a cure, there is generally a growth of new parts, termed from its appearance granu- lations, that tends to diminifh any vacancy produced. This fubftance is formed in larger or fmaller quantity, as the pati- ent is young or old, healthy or otherwife; and to fo con- fiderable a degree in young plethoric people, as often to rife above the level of the neighbouring integuments. When the lofs of parts is thus as far as poffible fupplied, the cure is then perfected by the formation of a cicatrix, either by a natural exficcation, forming a kind of cuticle or fcarfskin, or by the application of aftringents. Granu- lations feem jo confift, in every cafe, merely in an extenfion of the fmall blood veffels that have been divided, with a confiderable proportion of inorganic cellular fubftance, probably fecreted from thefe velTels, and which ferves to connect and fupport them; for it does not appear that or- ganicai parts are ever reproduced. But although granulations contribute very much to lef. fen vacancies occafioned by lofs of fubftance in ulcers, and particularly C 23 ] particularly in young people; yet this effect, in all cafes, is evidently chiefly produced by a diminution of the parts that remain. And cures, even of large ulcers are often obtained, efpecially in old people, without any evident growth of parts whatever. This part of nature's procefs, is to be remarked even in the fmalleft fores ; but is much more evident in the larger, and more particularly in thofe induced by amputation of the thigh. In ulcers produced by amputation, there is never any confiderable formation of new parts ; and the cure advances only in proportion to the contraction of the fkin caufed by the decreafe of the parts which it fur- rounds—This wafting takes place in every part but the bones; and is fully evidenced by diflection: for this teaches us, that even the largeft as well as the fmaller veffels, are entirely obliterated to a certain extent, and appear only as cords: the fibres of the mufcles are greatly diminiflied, and there is often hardly any trace of cellular fubftance. From what has juft been faid, it muft be plain, that compreffton, by the laced flocking and bandages, produce beneficial effects in ulcers; not only by preventing (Ede- matous and other fwellings in their vicinity but by con- tributing to the diminution of the adjoining parts. I have conftantly found more benefit to arife from compreffion, than from any other remedy; and as the laced flocking is not always well made, and is difficultly appli- ed, I prefer the roller to produce it. The rollers fhould be made of thin flannel, and ought to be about two and a half inches wide.—If the member is cedematous, they fhould be applied from its extremity to a little above the difeafed part; but if there is no cedematous fwelling, they fhould extend only from two or three inches below to as much above the fore. In the application of the bandages, they fhould always be fo managed as to fupport the fkin, and bring the edges of [ 24 ] of the fore as near together as poffible: for, as new fkia is never re-produced, or even an elongation of the old, all thofe parts which remain uncovered by it, will have nothing for their future protection, but a thin fcarf fkin. It is to be obferved, however, that compreffion is ne- ver to be employed while any confiderable degree of in- flammation remains in wounds; as foon, however, as this has a good deal fubfided, it will contribute exceedingly to expedite a cure by approximating the fides of the fore, and at length producing their coalefcence. The production of granulations in fores, is an Opera- tion of the fyftem itfelf: and all the affiftance art can af- ford, confifts in removing the obftructions which nature meets with in her progrefs. Thefe obftructions may be reduced to two general heads, thofe of an internal nature, and thofe which operate as external or local caufes. Of the former kind are, every general diforder to which the conftitution is liable; as we find, from experience, that a healthy flate of the body only is capable of pro- ducing proper granulations. Thus the cure of ulcers that occur in fyphilis, fcrophula and fcurvy, can never be properly effected, unlefs the general affection be firft cor- rected. A low emaciated ftate of body, alfo, either from a very poor diet, or from immoderate evacuations, is very preju- dicial to the growth of new parts. In general, the pati- ent fhould be fuffered to live fo as that he may be kept in a fituation at leaft not much more reduced than that of his common health. But as a variety of treatment in this refpect muft be neceffary in different cafes, the proper diet muft be directed by the judgment of the furgeon. The local obftruction to the granulation of ulcers, may be reduced to thofe that act mechanically, and thofe of a corrofive nature. As inflammation and pain contribute much to prevent the healing of fores, every thing, which bv C 25 ] by irritating, tends to excite them fhould be avoided— All ftimulant extraneous bodies fhould be taken away, and the dreffings fhould be mild and fimple, and changed but feldom. The corrofive fubftances that impede the cure of ulcers are chiefly the vitiated difcharges from them. Thefe are fometimes fo acrid, as not only to prevent the rifing of granulations, but even to corrode the neighbouring parts. They fhould be corrected, and if poffible, by the means hereafter to be pointed out, converted into pus. When the vacancies in fores are properly filled up, the remaining part of the cure confifts in the formation of a cicatrix. This is frequently, in a great meafure, a work of nature; but it may often be confiderably expedi- ted by the application of mild ftyptic powders and wafhes. Thefe, by corrugating the ends of the veffels, and ex- ficcating the cellular fubftance in which they are envelo- ped, tend very much to form that delicate covering term- ed cicatrix; which though at firft very thin, by fubfequent depofitions of inorganic fubftance, commonly acquires at length no inconfiderable degree of ftren'gth and firmnefs. The indications of cure in the fimple purulent ulcer, are, 1. To diminifh, as much as poffible, any vacancy the ulcer may have occafioned : and, 2. To promote the formation of a cicatrix. For the accompliftimen. of the firft, it is neceffary, as before explained, not only to have new gra- nulations formed, but alfo to produce a decreafe of the parts contiguous to the fore. In order to effect a production of new parts, we muft avoid the application of every thing that may occafion pain or irritation, as the warm gums, balfams, and fpirituous tinc- tures, which have been fo indifcriminately ufed in all fores, remove all corrofive matters, and make ufe of mild, bland unguents as dreffings. The following is one of the mofl ufeful of this clafs—&. of wax, §iv. fpermaceti, D ?iii. [ 26 ] §iii. oil ftj. Goulard's cerate is alfo a very good mild application. It is thus made : Take 4 oz. of refined wax, and tbj. of oil; keep them over a flow fire, until the wax is melted, ftirring them gently. Having previoufly mix- ed |iv. of extract of lead with ibvj. of water, add it gra- dually to the wax and oil, now cooled. Let them be well incorporated together with a wooden fpatula ; always taking care to let the quantity of water firft put in, be entirely abibrbed before any more is added. This oint- ment, as well as every other, fhould be made in fmall quantity at a time, as it is of confequence to have them free from rancidity. The frequency of dreffing ulcers muft principally de- pend on the quantity of matter difcharged ; but in general they fhould be dreffed once in twenty-four hours. The ointment fhould be fpread on pledgits of lint, and fhould be applied immediately after the removal of the preceding dreffings, in order to prevent the bad effects which often follow expofure of the fore for any time to the air. Some furgeons have advifed the renewal of the applications to fores but once in Sve or fix days. By this method, how- ever, and particularly in hofpitals, the air muft neceffarily be rendered impure. Ointments have been fuppofed by fome to render the granulations lax and flabby: but this I have never been able to perceive. Such effects are, indeed, produced by a long continued ufe of emollient fomentations and poul- tices—Lint applied immediately to fores, except the dif- charge is very great, gives too much irritation, and indeed always acts more or lefs as an efcharotic. The next circumftance requiring attention in this part of the cure, is to preferve the matter difcharged in a pro- per purulent ftate. This, in the fimple purulent ulcer, is chiefly produced by the prefervation of a proper degree of heat—Whilft any inflammation remains, this is beft ef- fected C 27 ] fected by warm emollient poultices, renewed every three hours; but as foon as the inflammatory fymptoms have abat- ed, they fhould be laid afide. The fame purpofe may then be better anfwered by applying over the dreffings thick quilted coverings of wool, cotton, or any fuch fubftances as retain heat mofl effectually. The other mod material part of the firft indication in the cure of ulcers is to be anfwered by compreffton. This is to be employed in the circumftances, and in the man- ner mentioned when we treated of ulcers in general. When the lofs of. fubftance in ulcers is fully fupplied, the fecond indication is to be attended to, viz. the formation of a cicatrix. This is frequently effected by nature alone ; but, in ma- ny inftances, it is a matter of confiderable difficulty. The emollient ointments muft be now laid afide, and the fore fhould be dreffed with fome ftyptic drying ointment, as the unguent album prepared with cerufs, and wafhed once or twice a-day with lime-water or ardent fpirits. Thefe will often fucceed. On fome occafions, cicatrization is prevented by the granulations rifing above the furface of the neighbouring parts. It is then neceffary to have recourfeto aflringent, or even efcharotic applications. One of the bed of the mild efcharotics is blue vitriol; if this is not fufficiently flrong, nothing weaker than the common cauftic ftone will be ef- fectual ; and in flight cafes of this kind, lint, and a pretty tight bandage will frequently produce a cicatrix. When every previous part of the cure has gone on very well, it often happens, that the granulations con- tinue raw, and fhow no tendency to heal for fome time; in thefe cafes, when the means we have recommended do not accomplifh the cure, compreffes wet with ardent fpi- rits, being applied under the roller, will often anfvver; or [ 28 ] or thefe may be alternated with tincture of myrrh, or a folution of blue vitriol in water. Befides local applications, there are fome general cir- cumftances very neceffary to be attended to in the treat- ment of ulcers. Reft of body, and particularly of the part affected, is very requifite: and, in all fores on the lower extremities, notwlthftanding what has lately been faid to the contrary, I am fully convinced by long experience, that a more perma- nent and fpeedy cure will be effected, if the patient can keep the limb in a horizontal pofture generally, than if he is permitted to take much exercife. The diet fhould be fo regulated, that the patient may be kept in his ufual habit of body. All exceffes in eating, as well as in drinking, fhould be carefully avoided. Internal medicines appear to be entirely unneceffary for the cure of the fimple purulent ulcer, except when the difcharge is uncommonly large and thin; in which cafe the peruvian bark is often a very ufeful remedy. SECT. III. Of the Simple vitiated Ulcer. The" vitiated ulcer differs only from the fimple purulent fore in the nature of the difcharge. The matter afforded is either, i. A thin, limpid, fometimes greenifh difcharge, termed fanies. i. A fome- what red-coloured, thin, and generally very acrid matter, termed ichor; or, 3. A more vifcid, glutinous kind of fluid, called forties. This laft is alfo frequently of a brownifh red appearance, fomewhat refembling the grounds of coffee, or grurnous blood mixed with water. They are all more fetid than pus, and none of them free from [ 29 ] from acrimony—What has been termed ichor, is often fo corrofive as to deflroy large quantities of the neighbour- ing parts. In confequence of the nature of the difcharge, the granulations wafte away, and have a dark brown or black appearance. The pain is often confiderable, and is proportioned to the acrimony of the matter. The caufes of this ulcer are the fame as thofe produc- ing the purulent ulcer; and that fpecies eafily degene- rates into this from neglect or improper treatment; and particularly when the tendinous parts are the feat of the difeafe. The progncfis in the vitiated ulcer, may be favourable when the complaint is not extenfive or is local, has not been of long duration, and occurs in young, healthy fubjects; but, in oppofite circumftances, it fhould always be very doubtful. The quality of the difcharge in ulcers has been above fhewn to depend chiefly on the different degrees of inflam- mation in the part; and this is further confirmed by the nature of the remedies that are mofl effectual in relieving thefe diforders, which are principally of that kind which remove pain and irritation. Thus warm emollient cata- plafms and fomentations often give great eafe, and meli- orate the difcharge within twenty-four hours: thefe fhould be ufed as formerly recommended to promote fup- puration, and the dreffings applied immediately to the fore fhould be mild, like thofe advifed in the fimple puru- lent ulcer, while too great a degree of inflammation con- tinues. When the pain is very confiderable, opiates fhould be given, and repeated according to circum- ftances. The diet muft be regulated by the habit of body; if weak, it fhould be nutritious; if full, the regimen fhould be low. In the former cafe, the peruvian bark is a very effica- _ 3o 3 efficacious remedy, and fhould be given in dofes of 5J. fix or eight times a-day. When the abovementioned circumftances are attended to, and the part affected is kept at reft in a proper pof- ture, the fore is commonly fooner or later reduced to the ftate of the fimple purulent ulcer; and then requires the fame method of treatment. I have never feen any evident good effects produced by the exhibition of nitre; although I have frequently given it in large dofes for a confiderable length of time.* SEC T. IV. Of the Fungous Ulcer. By fungus, or as it is fometimes termed hyperfarcofis, is meant fuch preternatural rifings in fores as are common- ly more foft and fpongy than healthy granulations. Thefe, in fome inftanees, arrive at a very confiderable fize; and now and then acquire very great degrees of hardnefs. The pain attending them is feldom confiderable; and the difcharge afforded varies according to the fpecies of fore they happen to be connected with while they are recent; but after fome continuance, this, as well as other circum- ftances become fo changed, as to form very different fores from thofe which originally exifled. Thefe excrefcences are often owing to the neglect of repreffing the granulations when they fhew a difpofition to advance beyond the furface of the found parts. They are alfo produced in various fores that are not healed at bottom, before granulations are fufrered to proceed any length. * It has, however, in a few inftanees, been attended with very hanpy effects in the cure of old habitual ulcers of the leg. length. Thefe inftead of cicatrizing when they are on a level with the found parts, continue to advance until the caufe is removed. With refpecl to the cure of fungi, when it is found that they are produced merely by an over-growth of parts, if they are not of any confiderable breadth, and efpecially if they are not very high, we fhould have recourfe to efcha- rotics.—By many, we are directed to ufe the actual caute- ry, and by others the fcalpel; but few patients will fub- mit to either of thefe, and particularly as the diforder may juft as effectually, though' net quite fo expeditioufly, be re- moved by means more gentle. Of all the cauftic preparations, the lunar cauftic is the beft for this purpofe. It acts more quickly, and does not give more pain than the milder forts ; it never fails to pro- duce the proper effect as many others do ; and it is not fo apt to run, and to fpread over the neighbouring parts, as fome of the other cauftics. The cauftics fhould be liquefied, and then applied by a fmall brufh or pencil, daily or every other day—A ftronj? / folution of verdigreafe, fal ammoniac, blue or white vitriol, will alfo commonly prove effectual. But folutions of fil- ver or mercury in nitrous acid form the mofl powerful applications of this kind. In making the laft we muft ob- ferve, that one ounce of flrong fpirits of nitre will diffoive no more than about fix drachms of quickfilver. Thefe cauftics fhould never be applied to an extenfive furface at once. After their ufe the part fhould be covered with lint, as ointments leffen their activity. When the bafe of the excrefcence is narrow and its height confiderable, it fhould be removed by a ligature ap- plied at its root, and tightened daily. If, however, toge- ther with great height, the tumor has a broad bafe, this me- thod will not fucceed; and the following muft be put in practice. 4 [ 32 _ A flrong ftraight needle fixed in a handle, with an eye near the point, being puflied through the tumor at its bafe, and two flrong waxed threads being introduced at its eye, it is to be again drawn back, leaving the threads with their ends hanging out at each fide of the fwelling. A firm liga- ture is then to be. formed round each half of the fv/ellingby the threads, and tightened from time to time. The fungus being by either of thefe methods removed, the fore is then to be treated as a fimple purulent ulcer. The other fpecies of fungous excrefcence which proceeds from the granulations not being raifed on a good founda- tion, is generally eafily diftinguifhed from the preceding fpecies : It rifes with greater rapidity, and is not fo firm as healthy granulations. As foon as the caufe is difcovered, any confined matter beneath fhould have vent given to it by a proper open- ing ; after which, by taking care that the fore fills up from the bottom, the cure will go on eafily in the common way. There is feldom then occafion for efcharotics, as the fungus commonly waftes away of itfelf. SECT. V. On the Sinuous Ulcer. By finuous ulcer is meant a fpecies of fore communi- cating with one or more openings or cavities, which are commonly feated in the cellular membrane, between the interftices of mufcles, or between the mufcles and integu- ments. By long continuance, or by the ufe of aftringent applications, a finus often becomes hard and callous in its internal furface ; and in fuch a ftate, from its fuppofed refemblance to a pipe, it is termed a fiftula. -1 The I 33 J" The mofl frequent caufe of finufes, is the want of a free difcharge of matter formed in ulcers and abfceffes; which, falling ^o the mofl depending firuahon of the part, if it does not there find a ready paffage by an opening made to it, readily infinuates itfelf into the cellular mem- brane, and proceeds gradually onward till it finds a vent. Very tight bandages applied immediately over a fore, and not made to act on the parts above and below for fome diftance, are alfo a frequent caufe. In healthy conftitutions, when there is eafy accefs to the finus, a favourable prognofis may generally be made; but when the difeafe has been of very long continuance, and particularly if the finufes open into any of the joints, or are beyond the reach of an operation, a cure is diffi- cult, and doubtful. The intention of cure, in every cafe of finus, is to pro- duce a coalefcence of its fides, fo as to deflroy any vacui- ty that may have been occafioned. To effect this, it is neceffary firft to make a depending orifice for a free exit to the matter; and then, by a gen- tle irritation, to induce on the internal furface of the fore, a flight degree of inflammation, and confequent adhefion of the fides of the finus. Both thefe intentions are anfwered by the introduction of the feton, from the orifice in the ulcer along the courfe of the finus to its other extremity, where an opening fhould be made in the manner we formerly directed in abfceffes. The treatment is then to be fimilar to that of abfceffes in which a feton is ufed. Vide chap. I. feet. iii. A cord fhould be intro- duced into every finus. This method is entirely free from danger, and is admif- fible in almofl every cafe that can occur. It is particu- larly proper in finufes in the perinseum: for the cicatrix formed there after the opening a large finus by the knife, E is [ 34 ] is often more inconvenient and painful than the original difeafe. The finufes being by this means filled up, the ulcers with which they have been connected, are then to be treated by the method adapted to the fpecies to which they belong. By many writers, ancient as well as modern, we are di- rected, in recent finufes, to ufe healing injections ; and when their fides have become callous, efcharotic injec- tions and powders have been recommended. None of thefe, however, produce any permanent good effects; and often convert fimple finufes into the callous. Others advife to lay open the different finufes, and cut out the whole of the callofities. This will often effect a cure; but the pain, and often the danger attending it, muft induce a preference of the mode above recommended. When, however, incifion is preferred, unlefs all the parts are evidently callous; in which cafe extirpation may be neceffary, mere divifion of the parts forming the finus fhould alone be ufed. The free vent thus giv- en to the matter, and the fuppuration fupervening, will frequently remove very confiderable callofities. SECT. VI. On the Callous Ulcer. An ulcer is faid to be callous when its edges, inftead of contratting and diminifhing the fize of the fore, keep at a diftance, turn ragged, and at laft, by acquiring a preternatural degree of thicknefs, often rife confiderably above the level of the neighbouring parts—the difcharge afforded [ 35 3 afforded by it, is commonly a thin vitiated matter. Vari- cofe veins alfo occur as a fymptom, and particularly when the difeafe is feated in the lower -extremities; hence the name of varicofe ulcer, which this fpecies has acquired, from a fuppofition that it was produced from matter fup- plied by thefe veins, which frequently have the appearance of opening into the fore. The varices feem to originate chiefly from an obftructed return of blood, by the pref- fure of the callous parts on the veffels. The caufes of callofities in ulcers may be all reduced to neglect and mifmanagement. When, from thefe circum- ftances, the fmall veffels of the edges of ulcers are prevented from proceeding in a proper direction, are forced to pufh upwards, and even fometimes backwards, they, by the preffure of bandages, will neceffarily acquire at length a morbid hardnefs or callofity. In the cure of this difeafe, the caufes originally produ- cing it are firft to be removed ; and the callofities may then be taken away. Recent cafes are often cured merely by the repeated application of warm emollient cataplafms—and alfo by gum-plafters ; but when the parts have acquired much hardnefs, the only remedies are the cauftic, or fcalpel. And as the firft is equally certain with the other, it fhould, as the eafieft method, be always employed. For the reafons formerly given, the lunar cauftic fhould here likewife be preferred. The folution of filver or of mer- cury in nitrous acid, may be alfo ufed to advantage. Ei- ther of thefe fhould be applied to the callous edges every two days, while the cataplafms are ftill continued as long as any degree of foulnefs remains in the fore. For the cure of the varices, it is not only neceffary to remove their primary caufe, the callofity, but like- wife to reftore the tone of the veffels weakened by their diflention, C 36 1 diftention, by the application of the laced flocking, or a roller*. A confiderable fwelling of the adjacent parts very com- monly occurs; when this dees not go off after the hard- nefs is removed, the ufe of a flannel bandage will ufually prove effectual in diffipating it. SECT. VII. On the carious Ulcer. By the term carious ulcer we underftand that fpecies. of the diforder only which is connected with a local affection of a bone : whether the difeafe of the bone may have been always confined to the part, or exifts after a general dia- thefis which originally gave rife to it has been removed.f When a bone is at firft laid bare, it is impoffible to de- termine whether it will become carious ; as in a great ma- ny inftanees this does not follow e>/en a removal of part of it. A cure fhould, hov/ever, never be attempted until this can be afcertained. If at the end of the fourth day after the denudation of a bone, it retains its natural appearance, we may conclude, with tolerable certainty, that a caries will not fucceed. For when this is to happen, it generally begins in three days or four at fartheft. The bone begins to lofe its natural heal- thy appearance, turns firft of a pale white, and then of a pale yellow. It fometimes remains in this ftate for fome days, * The growth of varices may be retarded by the ufe of the. roller or laced ftocking judicioufly applied ; but I never was able to cure old exten- five varices by thefe or any other means. f Caries appears evidently from its fymptoms, caufes, and method of cure, to be a difeafe exaftly of the fame nature with a fphacelus or gan- grene of the foft parts. B. L _•/ J days, and by degrees gets a more deep tallow-like appear- ance. It continues thus for a longer or fhorter time, ac- cording to the degree of violence with which the injury has been done; and afterwards goes through the differ- ent ftages of brown and black, until it has acquired a black of the deepeft dye. . The difcharge from ulcers of this kind, is generally thin; and of a moft difagreeable fcetor, which always be- comes more confiderable as the diibrder advances; at laft it acquires a blackiili hue, and often a confiderable de- gree of acrimony. As the fevcrai degrees of blacknefs go on, fmall holes appear in the bone, and increafe fo as at length to render it quite fpongy. The carious part then generally becomes loofe, and when preffed, a large quantity of a fattifli, intolerably fcetid matter is forced out. This taints the whole difcharge; and the fmell of it is fo very peculiar, as to afford one of the moft charac- teriftic marks of caries. The granulations in this ulcer are foft and flabby, fpring up in clufters, and have a dark brown, together with fome- what of a glaffy appearance. They ufually advance very faft, and if not carefully attended to, will be apt to form large and troublefome excrefcences. All the phenomena abovementioned, occur in greater or lefs degree, whether one lamina, or the whole fubftance of a bone is affected. When the bone has not been bared, it is often a matter of confiderable difficulty to difcover a caries. If we are able to introduce a probe, and by that means find a rough- nefs on the furface of the bone, we may, with certainty, conclude it to be carious. And when it is impoffible to reach the difeafed part with an inftrument, we may com- monly afcertain the exiftence of a latent caries, by the ap- pearance of the fere and the nature of the difcharge. The [ 33 3 The caufes of caries may be, in general, whatever de- flroys the circulation in the whole or any part of a bone: as wounds which affect either the periofteum or bones; violent contufions and inflammations of the periofteum, terminating in abfcefs or gangrene ; the acrid matter of ul- cers penetrating to, and deftroying the periofteum; and the improper application of fharp acrid fpirits and pow- ders to bones merely laid bare. It is to be remarked, that deftruaion of the periofteum, or even the removal of part of a bone is not always follow- ed" by caries; and this is feldomer a confequence of fuch in- jury to the cranium than to any other part of the body; probably from the greater number of blood-veffels diftri- buted to that part. The prognofis in caries muft depend principally on the following circumftances: The fituation of the difeafed parts; the nature of the affected bones; the nature and degree of the caufe; the fize of the caries ; the age and habit of the patient. Thus a caries in any of the bones of the flcull, ribs, or vertebrae, from their fituation near the vital organs, muft be attended with more rifle than when it affects the bones of the extremities. And a caries near a joint from the danger of this becoming difeafed, is always more to be feared than when it is confined to the middle of the bone. The texture of a bone fhould have alfo confiderable influ- ence in the prognofis; as well as the nature of the caufe : exfoliations being much more tedious in the hard and compact, than in the more foft and vafcular bones, and a wound with a fharp inftrument, does not generally produce fo deep or extenfive a caries as that which commonly fuc- ceeds to violent contufions. The cure is likewife produced in a longer or fhorter time as the caries is extenfive or not. And, laftly, the habit and age of the patient muft have ccnfiderable [ 39 3 confiderable weight in making a prognofis. For the cure of caries generally proceeds fo flowly, that few can fupport the difcharge it produces, if they have not previoufly been perfectly healthy. The healing of an ulcer, attended with caries fhould ne- ver be attempted, until the difeafed bone is removed. For if the foft parts above fhould be united, an abfcefs would be produced by the irritation of the bone beneath, and force them open. In a healthy flate of the body, the feparation of the cari- ous bone is produced, as in gangrene, by the intervention of a flight degree of inflammation excited on the extremity of the found parts—Suppuration follows, and this, together with the rifing of granulations, foon detach the dead from the living parts. If we fuffer ourfelves to be directed by this procefs of nature, we may often accomplifh in a few weeks what would otherwife require many more months to effect. The principal indication of cure therefore, it is evident, fhould be, by repeated and judicious applica- tions to excite fuch a degree of inflammation, in the adjoin- ing found parts of the bone, as may be requifite for the feparation of thofe mortified. If the bone is not bared, it fhould be expofed to view either by laying open the foft parts or removing fome of them. The fafefl and eafieft mode of exciting the necef- fary inflammation, is by making a number of fmall perfo- rations in the difeafed yart, with the pin or perforator of a trepan fixed in its handle, to fuch a depth as to give a lit- tle pain, every third or fourth day. When the caries is very deep and extenfive, it will fhorten the procefs to ufe the fmall head of a trepan.—As foon as any part of the bone becomes loofe at the edges, its feparation will be much haftened, by daily infinuating below them the end of a fpatula or levator, fo as to prefs them up- wards ': C 40 3 wards. During the feparation of the bone, in order to obviate the foetor, the fores fhould be walhed with a de- coaion of bark, of walnut leaves, camphor diffolved in fpirits, or lime-water. The latter I would advife to be al- ways ufed, as it not only corrects the foetor, but likewife diffolves the cohefion of the bony matter. Pledgits of lint dipped in thefe fhould be laid on the bone, while the reft of the fore is dreffed in the ordinary way. After the feparation of the caries, the ulcer is to be treated as a fimple purulent fore. When a very large portion, or the whole circumfer- ence of a bone is carious, the fhorteft procefs is to take out all the difeafed parts by the head of a trepan, ©r-a ftraight or circular fpring-faw. This may be done in all cafes where the difeafe is confined to the middle of a bone, except, perhaps, when the thigh bone is affected. There are many inftanees of the regeneration of whole bones; hence we fhould never defpair of a cure where the part difeafed can with fafety be removed. When the thigh bone is extenfively affiled, or when the ends of the larger bones forming joints, are carious, amputation is almoft the only remedy to be depended on. See chap, on Amputa- tion. ' During the treatment of caries, the fame attention is re- quifite to the patient's habit of body, diet, and regimen in general, as we have recommended in other fpecies of fores. The bark is almoft the only remedy that fhould be ufed internally; but when the foft parts become very painful and inflamed, flight fcarification, or bleeding with leeches, fhould be employed, and opiates fhould be given freely. SECT. [ 41 3 SECT. VIII. On the cancerous Ulcer.* Cancers have generally been divided into the occult and open. By the former are meant fuch hard fchirrous fwel- lings as are attended with frequent (hooting pains, and which generally terminate at length in the latter. By the open, or ulcerated cancer, we underftand that fpecies of fore wh'ch commonly fucceeds to hard fwellings of the glands, although in fome inftanees, it occurs without any previous hardnefs. The edges of this ulcer are hard, rag- F ged, * The following obfervations on Cancers, are the refult of the expe- rience of Mr. Berchien, a Swedifh furgeon of eminence; and who, in confequence of having purchafed Mr. Guy's remedy for twenty years, had a very great number of patients with cancerous complaints under his care from all the northern parts of Europe. They were publiftu d in the Swedifh language by Mr. Berchien, and by him fent to Dr. Adam Kuhn, the prefent profeffcr of the practice of phyfic in the univerlity of this place, who has favoured me with a tranflation of them. There are three fpecies of cancers : the cancer genuinus, fungnfus, and fcrophulofus. The cancer genuinus, or genuine cancer, is the moft common. It ufually appears firft in the form of a very fmall, hard, and moveable tumor or fchirrus: this is ufually fmooth and round: but in fome in- ftanees, it feels like a fmall tendon or firing. After fome increafe of fize, it often retains its fmooihnefs; but in other cafes, it becomes rough and angular, affumes the form of a cone, an almond, &c. It often continues of the fame fize for a number of years; but it alfo frequently continues conftantly to increafe in magnitude from its firft appearance. The tumor is at firft moveable, but after it has made fome progrefs, it becomes attached to the adjacent parts. When it advances near to the furface, it becomes very perceptible to the eye, and the fkin contracts a wrinkled appearance. A pain, in fome inftanees, is felt before any evident tumor, particularly in the cord-like cancer. In other cafes, there is no pain until the tumor appears; and in others again, which is moft frequently the cafs, the pain [ 42 3 ged, and unequal, very painful and reverfed in different directions. The furface of the fore is commonly very unequal. The difcharge is for the moft part a thin foe- tid ichor; and is often fo acrid as to excoriate and even deftroy the neighbouring parts, and by this means it fome- times produces confiderable hemorrhagies. There is a confiderable fenfe of heat over the whole ulcerated fur- face, which is the moft tormenting fymptom of the difeafe, and violent, {hooting, lancinating pains. Thefe are the moft frequent fymptoms of cancer, but they pain does not come on until the tumor has acquired a confiderable fize; but after the pain begins., the fwelling conftantly increafes in magnitude. Sometimes a momentary fhooting pain only is felt during the menftrual flux, or upon changes of weather; but in other cafes it is continual. Not long before the cancer becomes ulcerated, the fkin changes to a red colour, and is painful to the touch; it foon after becomes chapped, and a thin fanies iffues from the fiffures. The edges of the fore foon be- come hard and uneven, and are reflected in various directions. There is never a good pus afforded, but the difcharge is a thin fanies or ichor, which often deftroys the contiguous parts. This fpecies of cancer attacks various parts of the body; but particu- larly the lips, nofe, and breaft. The cancer fungofus chiefly occurs in fat women of a lax habit of body and who have large breafts. It begins like the genuinus, with a fmall moveable hard tumor; but it is more fpungy, elaftic, like a clufter of fmall tumors, and not fo hard. Its progrefs is aftonifhingly rapid: in fome inftanees it has grown from the fize of a nutmeg, to the biVnefs of a man's head, in the courfe of eight or ten months. Little blue or reddifh fpots, often appear over the furface of the tumor; which, when opened, difcharge blood, or a bloody ferum. When the cancer ulcerates, it difcharges fuch quantities of a bloody ferous matter, often all at once, that no dreffings can keep it dry. From one or more of the openings, arife large fpongy lobe-like excrefcenccs which fometimes have a refemblance to fheep's liver, and at other times have the form of the head of a cauliflower; and are hard and cartilagi- nous to the touch. Thefe often fpread over the, whole breaft, and are in fome inftanees, ftrangulated at their bafe by the fkin. This fpecies affeils not only the breaft, but alfo the neck, fhoulders arm?, and legs. The [ 43 3 they are often fo varied, that it is not always eafy to diftin- guifli the difeafe. When however, two, three, or more of thefe concur, we may always be pretty certain of the ulcer being cancerous. We may be a.ffifted in the diagnofis by the fituation of the fores : thus they generally affea glands, or parts in which glands are numerous? Hence a far greater num- ber occur in the lips and in the breafts of women than in every other part of the body. Various circumftances have been affigned for the pro- duaion The cancer fcrophulofus begins fometimes like the two other fpecies with a fingle fchirrus; but in moft inftanees, there arc feveral near each other, and which often feem connected: Thefe are not fo hard as in the genuinus, and give little or no pain until they become open fores, and even then but iittle. In the advanced ftages, the breaft appears co- vered with reddifh blue fpots, and is flat and hard. The integuments and fubftance of the breaft being drawn in, fo as to produce a furrow in the middle, and firmly fixed to the mufcles and ribs. This attachment often occafions a confiderable impediment to refpiration. The fubcuta- neous lymphatic glands become hardened in every part of the breaft, and particularly thofe towards the axilla. There arc many openings formed ; fome of thefe often dry up in a little time, and get a thick white fcab : others continue open—fome of them difcharge pus, others a thin foetid black ichor. The edges of the ulcers are frequently red and fungous; and the difcharge often penetrates at length to the ribs and ftcrnum, and even into the thorax. In this fpecies, there are ufually indurated lymphatic glands in various parts of the body, and other marks of fcrophula; and it evidently de- pends on a general affection. Tumors in the breaft from milk, have been accufed of terminating in cancer; but there is no good evidence of this; and where it has appa- rently been the cafe, I.have no doubt that there has, at the fame time, been a fchirrus in the breaft, which has become cancerous from the ir- ritation produced by the milky tumor. The general exciting caufes of cancers, are paflions of the mind, parti- cularly grief or terror, and external violence. In the cancer genu- inus and fungofus, t'ntfe operate locally by producing, probably an ©bftruction in the lymphatic veffels, and a conf.'quent fchirrus from a gradual accumulation of lymph, and abforption of its thinner parts; -but in the cancer fcrophulofus there is a general difeafe connected with the topical [ 44 3 duftion of cancers; and at leaft an equal number of re- medies have been propofed for the cure of them; but our little fuccefs in the treatment of the difeafe fhows clearly, that the ideas adopted, and the remedies offered, have been more founded on theory, than on obfervation and praaice. topical affection. From hence it is evident, that the cure of the latter can only be effected by conjoining the general remedies of fcrophula with proper applications to the cancerous part ; whilft the genuine and fun- gous cancers may be effectually removed by timely, topical remedies a- loue. The fcrophulous cancer may frtmetimes be cured by an early and judicious ufe of mercury, general and topical, and by hemlock ; but both of thefe are injurious in the other fpecies; for the cure of which, we can with fafety, only depend on early extirpation, or Guy's powder.----- As a confirmation of the accuracy of this interefting account of can- cer?. I am happy to give the teftimony of Dr. Jones, of this city, whofe long experience has afforded him an ample opportunity of afcertaining its agreement with the phenomena, nature, and proper method of treat- ing- thefe dreadful difeafes. The Doctor thus expreffes his opinion on the fubject:—Mr. Berchien's obfervations on cancers, appear to be the refult of accurate obferva- tion, and great experience ; from which alone any genuine improvement can be made in the cure of difeafes. His diftinction of cancers into the three general fpecies of genui- nus, fungofus, and fcrophulofus, is well founded, and merits the fe- rious attention of all thofe who wifh to treat this terrible difeafe with propriety. The two firft may be radically cuied by extirpation with the knife or cauftic, as they appear to be local difeafes: but the cancer -fcrophulofus requires the aid of internal medicine, to correct the vitiated habit; though very few inftanees occur of perfect cure. The cancer fungofus appears to be more liable to relapft than the ge- nuinus ; and inftanees have been known, where the cancer fungofus has broke out after it appeared to be perfectly cuied by Guy's powder, and remained found above ten years. The fame fpecies of cancer has been frequently clofed by the ufe of arfenic; but has often broke out agahi, and at laft baffled all remedies. Similar confequences have attended a quack noftrum, which has been much boafted of in this city for two years paft. From thefe inftanees, it appears to be a melancholy truth, that there are cancerous ulcers which baffle all the remedies hitherto difcover- ed. I 45 3 It however appears evident to me, that cancer is ge- nerally a W, affection, not originally conneaed with any conftitutional complaint; and that a general cancerous taint, feldom, or perhaps never occurs, but in confequence of the cancerous virus being abforbed into the fyftem from fome local affeaion. This opinion is more particularly rendered probable, by the fuccefs of extirpation in curing cancers. From a ftatement of Mr. Hill, furgeon in Dumfries, it appears that of eighty-eight cancers he had extirpated before the year 1768, in 1770 there were two of the patients not cured : in nine they had broke out again ; one was threatened with a relapfe ; and about forty remained alive and found. From thefe and many other authenticated facts, we think ourfelves warranted in drawing the above mentioned conclufion. The ill fuc- cefsoffome furgeons, and particularly of hofpital prac- titioners, may more juftly be attributed to the inveteracy of the cafes in which they have been ufually confulted, than to any thing really incurable in the nature of the difeafe. Cancers fucceed to external accidents : to tumors of the breafts in nuries and lying-in women mifmanaged ; to fe- vers and other internal diforders, of which they feem to be the terminations: and they happen to women about the time of the ceffition of the menfes. All thefe circumftances probably operate in bringing on cancer, by firft inducing a preternatural determination of fluids to the part, which necefTarily diftend and obftrua its veffels : from the fmall degree of irritability in thefe, the part affeaed being ufually glandular^an indolent tumor or fchirrus is thus gradually produced by the accumulation of fluid : this, at length, either from increafe of bulk or from external violence is excited to inflammation; which, at a lonaer or fhorter period, finally terminates in the forma- tion of the cancerous virus. This explanation will perhaps be admitted as agreeable [ 4<5 3 at leaft to probability, if we confider that glandular parts, which are almoft always, if not in every cafe, the feat of cancer, never afford a good difcharge : and, from the analogy of many other fores which often produce a mat- ter nearly as acrid as the cancerous virus, we may certain- ly be allowed to infer, that fome peculiar affeaion of thefe parts may induce the formation of a matter as acrid as that of cancers : and when the virus is thus formed, it may in time be abfoibed, and produce a general cance- rous diathefis. There is no remedy to be depended on in cancers but ex- tirpation ; and it fhould be had recourfe to immediately on the difcovery of the difeafe. With refpea to the parti- cular modes of performing this operation, we muft refer to what will be faid hereafter; and fhall only obferve in this place, i. That cauftics, on account of the irritation and inflammation they produce, fhould never be preferred to the fcalpel. 2. Wherever the diforder is fituated, eve- ry part that has the leaft appearance of difeafe, every indurated gland in the neighbourhood fhould be always taken off*", otherwife the cancer will certainly return; but no more of the integuments fhould be removed than is abfolutely neceffary : for the fmaller the cicatrix that remains, the lefs will be the confequent irritation ; and from this, perhaps, the chance of the difeafe returning may be leffened. The teguments fhould, as far as poffible, be brought to cover the wound by the employment of the interrupted * From a circumftance which occurred in a cafe of occult cancer of the mamma extirpated by Dr. Hutchinfon, of this city, and of which I was a witnefs, I mould think it very proper, in every inftance, to avoid cutting the tumor. After the operation, the Doctor's pupil wifhing to examine the whole fubftance of the cancer, made an incifion into it, and there immediately iffued forth a confiderable quantity of a thin icho- rous matter. The patient very foon recovered; which, perhaps, might not have been the cafe had this matter been difcharged into the wound. For it is very well known that cancerous fores have been fome- times produced from the application of the virus, even to parts covered \vith the integuments. [ 47 3 interrupted or twifted future. 3. After the removal of the cancer, if the teguments do not entirely cover the wound, and a hemorrhagy enfues, dry lint fhould be ufed as a dreffing; but if there is no difcharge of blood, the lint fhould be fpread with fome emollient ointment. The fore fhould afterwards be treated as a fimple ulcer, and healed as foon as poffible. 4. Some little time before the healing of the fore, an iffue fhould be introduc- ed—and this is probably done with greatefl advantage, if made within the vicinity of the cancer. Iffues feem particularly neceffary in cafes of cancer that proceed from fuppreffed evacuations, and have continued a long time; and we have no doubt, but that they often "prevent the return of the difeafe. The circumftances that fhould prevent the extirpation of cancers, are, in general, 1. The appearance of cance- rous ulcers and fchirrous glands in feveral parts of the body at the fame time. 2. The conneaion of them with other parts that cannot be removed without danger. Thus cancers adhering to the trachea, or to the coats of a large artery, can never, without the greatefl rifk, be extir- pated. But large portions of mufcles and tendons have been taken away with cancers without producing much inconvenience. And there have occurred many inftanees of cancerous mammas, in which there were adhefions to the periofteum of the ribs, to the clavicle, and fometimes a chain of indurated glands, extending to the bottom of the arm-pit, and yet all the difeafed parts were with per- fea fafety removed. 3. An operation can never be advifeable, where the parts affeaed are fo fituated, as to prevent their being to- tally extirpated; as is the cafe in cancers of the uterus and reaum. The indication then, is to palliate the different fymptoms, fo as to render the difeafe as tolerable to the patient as poffible. As, for this purpofe, the great objea is [ 48 3 is the abatement or prevention of pain, nothing fhould be exhibited internally, or applied externally, that can have the leaft effea in producing irritation or inflammation. A diet of milk, and the lighteft vegetables fhould be or- dered : no animal food, fermented or fpirituous liquors, fhould be allowed; and all violent exercife fhould be carefully avoided. The foetor of cancers is confiderably correaed by the ufe of hemlock. This may be taken internally in powder or extraa, and applied externally with emollient poulti- ces in powder, if the juice cannot be had. It commonly alfo mends the difcharge; and this much fooner than the carrot-poultice that has been fo much recommended in foul fores*. When a good difcharge is obtained, the fore fhould be treated as a fimple purulent ulcer—and particular atten- tion fhould be paid to avoid long expofure of the ulcerat- ed furface to the air. The violent fhooting pains are re- lieved fometimes by cicuta—and fometimes by emollient fomentations—when neither of thefe fucceed, we muft have recourfe to opiates. Befides a variety of other remedies, cicuta, belladonna, and arfenicf, externally as well as internally, have been much employed and recommended for the cure of cancers ; but we have * Similar good confequences have fucceeded the ufe of common poke —the ley-poultice—and of fixed air. f Arfenic has been probably the bafis of moft of the quack medicines for cancer; fuch as Guy's, Plunket's, and others. Dr. Rufn has proved, by a chemical analyfis, that Martin's remedy contained this fubftance. It has been obferved to occafion various fpaimodic affe&ions in fome in- ftanees, and particularly to affect the mufcles of the eyes. We have good evidence of its producing beneficial effeds in many inftanees, and of ef- fecting cures in fome. If it is propofed to apply arfenic to an occult cancer, it will be necef- fary to deftroy the cuticle by the lunar cauftic or fome other fubftance, or by [ 49 3 have never feen any of them produce any permanent advan- tage. Mr. Juftamond has fpoken highly of an efcharotic me- dicine compofed of fteel and fal ammoniac, infufed in fpirit of wine, with a certain proportion of oil of tartar and fpirit of vitriol. The edges of the cancers, as well as the hard cxcrefcences that occur in them, are to be conftantly moift-' ened with this liquid ; and during the ufe of it, he like- wife advifes the internal ufe of flores martiales. From the trials I have made of thefe remedies, I have not ex- perienced any real advantages. SECT. IX. On the Cutaneous Ulcer. There are few difeafes lefs underftood than thofe of the fkin. The defcriptions given of them are fo confufed ; and they are fo varioufly named by different writers, that it is difficult to collea any thing on the fubjea fatisfaaory. We fhall here confine ourfelves to fome general obferva- tions on thofe topical complaints of the fkin that are apt to produce troublefome ulcers. Thefe, as well as fome others, have all been included under the general term of Herpes^ from their being apt to fpread from one part to another. The chief varieties of herpes may be comprehended in the four following fpecies, viz. the Herpes farinofus, puflu- lofus, miliaris, and exedens. G The by a knife, previous to its ufe. Mr. Juftamond does not think it neceffary in any cafe to apply it over tha whole furface of the tumor, but merely to its circumference. He is of opinion that arfenic operates in feparating the cancer by exciting an inflammation, and confequent fuppuration, of the found parts connected with thofe difeafed. The arfenic is ufually applied either in form of a watery folution, aj ftrong as it can be rnadet or mixed with fome unguent, or powder. [ 5° 3 The herpes far i ncfus, or what may be termed the dry tet- ter, is the moft fimple of all the fpecies both in its nature and treatment. It appears indifcriminately in different parts of the body; but moft commonly on the face, neck, arms, and wrifts, in pretty broad fpots of exceeding fmall red pimples. Thefe are generally very itchy, but not other- wife troublefome; and after continuing a certain time, they at laft fall off in form of a white powder, fimilar to fine bran ; leaving the fkin below perfeaiy found; and again returning inform of a red cfflorefcence, they fall off, and are renewed as before. The herpes pufulofus appears in the form of puftules, which are originally feparate, but afterwards run together in clufters. At firft they feem to contain nothing but a thin watery ferum, which afterwards turns yellow; and ex- uding over the whole furface of the part.affeaed, it at laft dries into a thick cruft or fcab. When this falls off, the flrin below frequently appears entire, with only a flight de- gree of rednefs on its furface ; but on fome occafions, when the matter has probably been more acrid, upon the fcab falling off, the fkin is found flightly excoriated. Erup- tions of this kind appear moft frequently on the face, be- hind the ears, and on other parts of the head ; and they occur moft commonly in children. The herpes miliaris breaks out indifcriminately over the whole body; but more frequently about the loins, breaft, perinseum, fcrotum and inguina, than in other parts. It generally appears in clufters, though fometimes in dif- tina rings or circles, of very minute pimples, which from their refemblance to millet, have given the denomina- tion to the fpecies.—The pimples are at firft, perfeaiy fe- parate ; and contain nothing but a clear lymph, which, in the courfe of the difeafe is excreted upon the furface; and there forms into fmall diftina fcales; thefe at laft fall off, and leave a confiderable degree of inflammation be- low, that Hill continues to exude frefh matter, which like- wife [ 5* 3 wife forms into cakes, and fo falls off as before—The itch- ing in this fpecies is always very troublefome: and the matter difcharged from the pimples is fo tough and vifcid, that every thing applied to the part adheres in fuch a man- ner as to occafion a great deal of uneafinefs on its being removed. The different fpecies of herpes are in common known by the names of tetter, f jingles, and ring-worm -, but the laft is moft frequently applied to the herpes miliaris. The herpes exedens, fo called from its deftroying or cor- roding the parts which it attacks, appears commonly at firft in the form of feveral fmall painful ulcerations, all colleaed into large fpots of different fizes, and of various figures, with always more or lefs of an eryfipelatous-like inflammation. Thefe ulcerations difcharge large quanti- ties of a thin, fharp ferous matter; which fometimes forms into fmall crufts that in a fhort time fall off; but moft frequently the difcharge fpreads along the neighbouring parts, where it foon forms ulcers of the fame kind. Although thefe excoriations or ulcers do not, in general, proceed further than the true fkin; yet fometimes the difcharge is fo corrofive as to deftroy the fkin, cellular fubftance, and on fome occafions, even the mufcles them- felves. It is this fpecies that fhould properly be termed the depafcent or phagedenic ulcer; but ulcers of the herpetic kind have, with great impropriety, been com- monly fuppofed conneaed with fcurvy, and thence, have been termed fcorbuiic: Whereas it is very certain, that herpes is a complaint generally joined with a ftate of the body entirely oppofite to that which takes place in fcurvy, viz. the plethoric and inflammatory, is very differ- ent in its appearance from fcorbutic ulcers, and requires very oppofite remedies. This fpecies of herpes appears at different times in every part of the body, but moft frequently about the loins, where it often fpreads fo as to furround the whole waift. It C 52 3 It feems to be eafily communicated by contagion; that is, by the application of the virus, by the intervention of clothes and other fubftances. I have known even the dry fpecies of the diforder communicated thus. There is as much confufion and uncertainty among au- thors refpeaing the cure of cutaneous difeafes, as with re- gard to their defcription. It has always been fuppofed, till lately, that thefe complaints originated from fome ge- neral morbid affeaion of the fyftem. And it was even be- lieved to be unfafe to attempt their cure in any other way than by correaing the difeafe of the fluids which it was fuppofed produced them. But it is ftrange that this opi- nion fhould not have been rejeaed when it was known that they could be cured by topical applications. It was formerly the praaice to direa long debilitating courfes of medicines—but whenever internal medicines are now di- reaed, it is with a view to reftore the diminiflied difcharge of perfpirable matter ; which, from want of cleanlinefs, and from fome other caufes, being long retained on the furface of the body, and there turning acrid, may often, it is pro- bable, give rife to many cutaneous affeaions. And, ac- cordingly we find, that all fuch remedies prove more or lefs effeaual as they keep up a more or lefs free perfpira- tion. And what puts it beyond a doubt that they pro- duce their good effeas in this manner is, that warm bath- ing and cleanlinefs alone, in many inftanees, will cure thefe difeafes effeaually. In the treatment of all the fpecies of herpes, the firft and principal circumftance to be attended to is, that not only the parts affeaed, but even the whole furface of the body, be kept as clean and perfpirable as poffible; for which pur- pofe nothing is of fo much importance as the frequent ufe of warm bathing, together with gentle friaions, with clean linen cloths; this laft, in the dry fpecies, may be applied over the difeafed parts. When thefe circumftances are properly [ 53 3 properly attended to, few or no internal remedies are ne- ceffary in the flighter degrees of herpes. Of external applications, the feveral drying and aftringent remedies are moft to be depended on—lime-water, decoc- tions of the different kinds of boles, and of the aftringent earths, often remove flight cafes of thefe complaints. A watery folution of faccharum faturni, applied in cataplafms, or on foft linen rags, is fomewhat more powerful—But in inveterate cafes, a folution of corrofive fublimate of mercu- ry in water is more to be depended on than any of thefe. About 10 grains to fbj. of water is in general a proper proportion. Ointments prepared with thefe fubftances are not more effeaual than the watery folutions; the latter are more cleanly, and therefore claim a preference. When the difeafe has been of long ftanding, and efpeci- ally if large quantities of matter are difcharged, it becomes neceffary to have recourfe to other remedies. The more obftinate and virulent fuch complaints are, the o-reater attention becomes requifite to the promotion of a free difcharge by the fkin; for which purpofe, together with warm bathing, warm diluent drinks, fhould be plen- tifully allowed. New whey anfwers in this view very well. Although farfaparilla and mezereon have been much re- commended for this purpofe, I never knew them to pro- duce more beneficial effeas than the common decoaion of the woods. This may be rendered occafionally more diaphoretic by adding fifteen or twenty drops of tinaure of antimony to each cup full. A free perfpiration may in common be kept up by taking two or three pounds of the decoaion in the courfe of every twenty-four hours. Crude antimony, to the quantity of two drachms in the day, is alfo a ufeful and gentle diaphoretic. Its efficacy is often rendered greater by conjoining a fmall quantity of gum [ 54 3 gum guaiacum with it, by which means it proves gently purgative. In plethoric patients, laxatives often prove ferviceable. Thofe of the cooling kind only fhould be ufed. Sea-wa- ter anfwers very well, when the patient's flomach will bear it; but cream of tartar made into an efeauary with an equal quantity of fugar, and fome mucilage of gum ara- ble, forms a much more agreeable laxative. An iffue is always neceffary in the more inveterate fpe- cies of herpes, and fhould be one of the firft remedies; without which, as in ulcers, the difeafe is very apt to re- turn after being cured. As confiderable inflammation fometimes attends herpes, and particularly the herpes exedens, the faturnine applica- tions become very neceffary. Warm poultices and fomen- tations almoft conftantly tend to increafe the difeafe, by fpreading the humour. When the ulcers penetrate deep, it is neceffary to drefs them with ointments, corapofed either of zinc, faccharum faturni, or white precipitate of mercury, and hog's lard. The proportions of zinc and axunge may be 5'ij. in fine powder of the former to 5vi. of the latter. When thefe remedies do not fucceed in the cure of her- pes, which is feldom the cafe, there will be reafon to fufpea that fome other difeafe fubfifts at the fame-time— This, on accurate examination, will frequently be found to be the lues venerea. In this cafe, mercury muft be add- ed to the remedies already advifed. A combination of fcabies or the itch with herpes fome- times occurs, and produces a tertium quid, almoft as loaihfome as the leprofy. In this cafe, the treatment ne- ceffary for fcabies muft be joined with that ufed for the removal of the herpes. Mercury will frequently cure the itch, and often removes herpes; but as it fometimes fails in C 55 3 in the former difeafe, and fulphur hardly ever does, the latter fhould be preferred. In every herpetic eruption to which children are liable, fulphur feems the moft effeaual remedy; and when others have failed it fhould always be tried. The fulphur vivum is much flronger than the flores fulphuris, and fhould therefore be ufed in preference. There is a variety of herpes, which frequently affeas the face, and occurs more particularly in females, ex- ceedingly diftreffing and difficult to remove—All the common remedies are often ineffeaual in curing it. I have fucceeded in many fuch cafes by the ufe of the following preparation: $,. lac. fulphuris 5ii. facchar. faturni ^j. aq. rofar. |viii. m. The eruption is to be bathed with this, morning and evening, firft fhaking the vial. When, however, it is thought proper to ufe mercury, the ungu- entum citrinum, prepared with a lefs quantity of acid than is ufually employed, is the moft effeaual preparati- on of it I have ever ufed. The tinea capitis and crufta laaea of children, belong to the fpecies of herpes puftulofus, and require the fame ge- neral treatment. In the former, it is of great confequence that the hair fhould be cut fhort; and the folution of fublimate fucceeds remarkably well. Iffues-feem particularly ufeful in curing and preventing herpetic difeafes in children; and they may, with the greateft fafety, be healed up after the fifth or fixth year of their age. As the quantity of fluids which, before that period, appears to be difcharged by different eruptions upon the furface, feems then neceffary to be applied to the fecretions of the body. ' SECT. C 5^ 3 SECT. X. On the Venereal Ulcer. We now come, in order, to confider the ulcers con- neaed with a general affeaion of the fyftem; and fhall firft treat of the venereal ulcer. Although, by the term venereal ulcers, is generally meant thofe which are a part of fyphilis ; yet chancres, which are not always conneaed with any general difeafe are alfo included under it. They may therefore be divid- ed into thofe that appear as primary fymptoms of the difeafe, and fuch as may be more properly confidered as fymptomatic. Of the former kind are chancres in general, wherever fituated, whether upon the parts of generation, the nip- ples, or lips. Thofe ulcers may alfo, in fome cafes, be reckoned primary, which remain after the burfting of bu- boes that have arifen from an infeaion lately communi- cated, and before there is a probability that the whole fyftem is affeaed. Such ulcers are confidered as fymptomatic, as arife in confequence of a general taint of the habit. Of this kind are all thofe which fucceed to old buboes, and fuch as appear along with other venereal fymptoms a confiderable time after infeaion ; the moft common fituations of which are, the throat, palate, nofe, the parts immediately above the bones of the cranium, tibia, humerus, and other hard bones thinly covered with flefh. In many cafes, it is difficult to make this diftinaion in venereal fores ; but unlefs it is always done, we cannot di- rect the proper mode of treatment. The principal means of diftinaion are obtained either by information from the patient t 57 3 patient, or from the appearance of the different fores themfelves. If, foon after expofure to infeaion, an ulceration appears upon the part to which the virus was immediately appli- ed, together with fweUings of any of the glands in the courfe of the lymphatics, we may be almoft convinced that thefe are only local affections. Such ulcerations are termed chancres. They appear at firft, as fmall miliary fpots, which foon rife and form little veficles; thefe upon burfting, difcharge fometimes a thin watery fluid, and on other occafions, a more thick yellow matter. The edges of fuch fores are generally hard and painful; and as well as the glandular fweUings already deferibed, are com- monly attended with more or lefs inflammation. The fymptomatic venereal ulcers are in general, more troublefome than chancres. They are diftinguifhed, i. By information from the patient. 2. By their fituation; and, 3. By their appearances. Thus if a patient who has fymptoms of infeaion in his conftitution, is attacked with one or more ulcers, whether in confequence of exter- nal injuries or not: and if they refill the common me- thods of cure, there can be little doubt of their being in- feaed by the general taint. But when it cannot be af- certained that the patient is affiled, by his own informa- tion, we muft endeavour to form a judgment from the fi- tuation and appearances of the ulcer itfelf. Venereal ulcers from an old infeaion generally appear immediately above the bones, and particularly above fuch as are but thinly covered with mufcles. They firft ap- pear in the form of a red, and fomewhat purplifh efflo- refcence, confiderably diffufed. This foon rifes into a number of very fmall puftules, which ooze out a thin fretting ferum. At firft, thefe puftules when obfervcd through a glafs, appear perfeaiy diftina ; but they at laft run together, and form one large ulcer, whofe edges are H commonly commonly ragged and fomewhat callous ; and there is ge- nerally a light red appearance, extending a confiderable fpace beyond the fore and efflorcfcence. Sores of this kind have frequently the form of a cup, with the narrow part at the bottom. But when carious bones lie at the lower parr, they are generally filled up with fungous excrefcences. They are feldom attended with much pain. The difcharge from them is at firft thin, but at laft puts on a very charaaeriftic appearance; being of a confiftence rather more vifcid and tough than good pus, with a very loathfome, though not the ordina- ry fetid fmell, and a very fingular greenifli yellow colour. . The diftinaion of venereal fores into primary and fymp- tomatic, is of confequence in direaing the proper treatment. For the former might be cured merely by deftroying the venereal matter with cauftic, if attended to before any ab- forption had taken place. But as it is impoffible to afcer- tain whether the virus has entered the fyftem or not, when we are applied to, the cure of chancre fhould never be trufted to topical applications; but, together with thefe, .mercury fhould be always ufed internally ; and to prevent a further abforption of matter, the healing of the fore fhould be accompliihed as foon as poffible. This diftinaion points out to us likewife, that in ul- cers from an, old pox, we ought never to make ufe of fuch dreffings as have a tendency to heal them foon ; but fhould rather truft entirely to the internal ufe of mercury, and to fuch applications as merely keep them clean and eafy. For the healing of fuch fores then affords the fureft index of the removal of the general difeafe. As we are feldom called early enough to deftroy the virus in chancres by cauftic, and indeed until it would be fomewhat dangerous to attempt it, after wiping the fores clean, I generally fprinkle them with finely powdered red precipitate of mercury, and over this apply lint fpread with -' C 59 3 with common ointment. This anfwers very well in all cafes unattended by inflammation. It feldom occafions much pain or irritation: and produces a flough, which in the courfe of a dreffing or two, generally comes away, and leaves the ulcer perfeaiy clean. When in this ftate, the fore would probably heal if nothing more than cerate was applied to it, but for fear any venereal matter fhould ftill remain, I commonly then drefs it with the flrong mercurial ointment. In this manner chancres are in general eafily cured, and with much lefs mercury given internally than if allowed to remain open a confiderable time. By long continuance however, and the neglea of proper remedies, thefe ulcers put on the appearances and nature of thofe that depend on a general infeaion ; and confequently require the fame method of treatment. They are very apt to become inflamed and very painful; and more efpecially when feated on the penis. Where this is the cafe, it is fometimes neceffary to order bleeding: but in general, the faturnine poultice will be fufficient to moderate the inflam- mation. After the removal of the inflammatory fymp- toms, the beft application is common wax ointment. There are two modes of throwing mercury into the fyf- tem ; the one by giving it internally by the mouth, and the other by introducing it into the body through the abfor- bents on the fkin by means of friaion ; but, as the laft me- thod is by much the moft troublefome and inconvenient, and is not attended by any peculiar advantages, the former is now, I believe, generally preferred. Thofe preparations in which the mercury has undergone no other operation than triture, as the quickfilver pill, P. Edinb. are in general the beft. When this is not found to anfwer,* the mercurius corrofivus fublimatus, or mercurius calcinatus, may be tried : and it is fometimes neceffary to ufe a variety of preparations before a cure can be effeaed. But [ 6o ] But, in whatever form mercury is employed, it fhould always be continued until a forenefs of the mouth is in- duced, as that is the only certain indication of its having entered the fyftem. This forenefs in very fight degree, fhould be fupported until the cure is perfeaed. In order to guard againft the mercury's running off too quickly by the mouth, and producing troublefome faliva- tion, which it is very apt to do, it has been recommended to determine the operation of the medicine in fome degree to the fkin by the ufe of warm bathing—not only during the ufe of the mercury, but previous to its being begun—This effect may, in fome degree, be obtained with lefs rifle from cold, by the ufe of a flannel fhirt, by drinking plentifully of decoaion of the woods or farfaparilla: and by avoid- ing cold. Where the warm bath can be conveniently ufed it fhould, as being more powerful in its effeas, without doubt be employed. It alfo has a good influence in pre- venting the operation of the mercury on the bowels. By the ufe of thefe different remedies, venereal ulcers will commonly foon be removed. The mercury fhould be continued for a longer or a fliorter time after the difap- pearance of the fymptoms, according to the inveteracy or ftanding of the difeafe. It fometimes happens that after a long exhibition of mer- cury, and when there is reafon to fuppofe that the venereal taint of the habit is altogether eradicated, the ulcers can- not be brought to heal. In this cafe there will be room to fufpea that fome other difeafe may have fubfifted in the conftitution together with the lues venerea, and that both may have had fome fhare in the produaion of the ul- cers. When the nature of this diforder is afcertained, proper remedies to correa it muft be conjoined with thofe before given. Venereal C 61 3 Venereal ulcers are fometimes rendered obftinate by a caries of fome bone, independent of any other difeafe. This is to be fufpeaed when they are feated upon or near any of the bones, and particularly if there occur fungous excref- cences. To the remedies for the venereal affeaion, we muft then add the treatment proper for caries. See feaion on the carious Ulcer. When neither caries nor any conftitutional affeaion feem to prevent the healing of fuch ulcers, and they appear to grow worfe; and particularly when the fyftem feems much debilitated by the confinement and effeas of the re- medies, the beft and moft effeaual mode of treatment is, to order a light nourifhing diet, with frefh air and exercife. This by invigorating the body often produces furprifing cures. The Peruvian bark is here alfo of fervice. Old fores of this kind, on account of the floughs with which they are ufually covered, require ftimulant dreff- ings. The following ointment is very proper, §> ung. bafil. flav. |j. mere, prsec. rubr. 5'ij. M. When they be- come clean, they are to be treated in the ufual way. When the glands are the feats of venereal ulcers, it is fometimes neceffary to deftroy the whole, or a confidera- ble part of fuch as are much hardened, by cauftic, before a cure can be obtained. Although venereal ulcers are in general to be cured by proper treatment, yet fome inftanees have occurred, in which they have refilled ail the efforts of nature and art, and at laft have carried off the patient in great mifery.—* Such cafes probably are only to be met with in hofpitals. SECT. * They are fometimes met with in private practice, and after refilling all the methods recommended by different writers, have been known to recover folely by the ufe of a free diet and exercifej [ 62 ] SECT. XI. On the Scorbutic Ulcer. The charaaeriftic marks of ulcers that occur in fcurvy, are as follow:—They never afford a good pus ; but a thin foetid fanious matter, mixed with blood ; which at length has the appearance of blood coagulated, and is with difficulty feparated from the furface of the fore. The flefh beneath this is foft, fpongy, and very putrid.—Efcha- rotics to remove the floughs anfwer no good purpofe, for they certainly appear again at the next dreffing—Their edges are generally of a livid colour, and puffed up by excrefeences beneath the fkin. If compreffion is employ- ed to keep the fungus from rifing, it generally produces a gangrenous difpofition, and always renders the member cedematous, painful, and for the moft part fpotted. As the difeafe increafes, they flioot out a foft bloody fungus, refembling boiled liver ; which often rifes in a night's time to a monftrous fize; and if deftroyed by cauftic or the knife, bleeds plentifully, and returns again by the next dreffing. They continue a confiderable time in this condition, without affeaing the bones—and are produced by the flighteft wound or bruife, in fcorbutic perfons. This defcription is only applicable to fcorbutic ulcers that accompany very great putrefceacy in the fyftem at large ; for fuch inveteracy is not often met with, except in long fea-voyages ; but in Scotland, flighter degrees of the fame kinds of fores are often feen, and fometimes ac- companied with the moft charaaeriftic mark of fcurvy, viz. foft fpongy gums. They generally appear among' the loweft clafs of people, and feem to originate rather from want of food in general, than from confinement to a particular C 63 3 particular kind. They feldom are produced in parts pre- vioufly found; but ulcers already formed, and wounds infliaed during the prevalence of a fcorbutic affeaion, always degenerate into fores of this kind. Moft of the ulcers of the poor in Scotland partake of a fcor- butic taint. The immediate or proximate caufe of fcorbutic ulcers, as well as of every other fymptom of fcurvy, may be re- ferred to a certain degree of putrefcency in the fluids. This may be induced by a variety of caufes, the moft ma- terial of which are, living conftantly upon fait provifions ; a total want of vegetables ; with expofure to a cold, moift atmofphere. See Pringle, Lind, and Huxham, on the Scurvy. The cure of fcorbutic ulcers muft depend chiefly on the correaion of the putrid diathefis of the fyftem ; for which purpofe, vegetables of all kinds, but efpecially thofe of an acefcent nature, with milk and whey, are found to be cer- tain remedies. The different fecretions, efpecially thofe by the kidneys and fkin, and more particularly the laft, which is in common almoft entirely obftruaed, fhould be gently promoted. Laxatives, as tamarinds, manna and cream of tartar, are alfo very ferviceable—Thefe remedies, joined with total abftinence from faked food, and atten- tion to avoid all the other exciting caufes, commonly re- move all the fymptoms of fcurvy. The ulcers fhould be dreffed with powerful antifeptics. Lind recommends ung. aegyptiac. and mel rofarum acidulated with fpirits of vitriol. In the fcorbutic ulcers that occur in Scotland, it is feldom neceffary to confine the patient to an antifcor- butic courfe. And they are more effeaually removed by the gradual allowance of a generous diet, with a moderate proportion of good wine, or perhaps what is better, of porter or flrong beer. Peruvian bark internally C 64 3 internally, and applied to the ulcers in decoaion, is a very ufeful remedy in thefe cafes; but the beft external appli- cation while much putrefcency remains, is the carrot poul- tice ; when this is removed, the ulcer is to be dreffed as in other cafes. Iffues are alfo to be ufed occafionally. SECT. XII. On the Scrophulous Ulcer. By fcrophulous ulcers, are meant thofe fores which are confequent to fweUings, fymptomatic of fcrophula or king's evil. Scrophula begins with indolent, fomewhat hard, co- lourlefs tumors; which at firft chiefly afft-a the conglo- bate glands of the neck; but at length attack the cellular fubftance, ligaments and bones.—Thefe fweUings are more moveable than fchirri, fofter, and feldom much painful; they are tedious in coming to fuppuration ; very apt to difappear fuddenly, and again to rife in fome other part of the body. There is a remarkable foftnefs of fkin in this difeafe, a kind of fulnefs in the face, and generally large eyes, and a very delicate complexion. Scrophulous ulcers feldom yield a good difcharge; af- fording upon their firft appearance, a vifcid, glairy, and fometimes a whitifh curdled matter, that afterwards changes to a more thin watery fanies. The edges are frequently painful: and always much tumefied. As long as there is any fcrophulous diathefis in the fyftem, fuch fores often remain for a great length of time, without fhowing any difpofition either to heal or grow worfe : at other times they heal very quickly, and again break out in fome other part of the body. A variety of caufes have been mentioned as tending to produce fcrophula, viz. a crude indigeftible food ; bad wa- ter; C «S 3 ter; living in low damp fituations ; its being an heredi- tary difeafe, and in fome countries endemic, &c. But, whatever may be the exciting or predifpofing caufes, the difeafe itfelf either depends upon, or at leaft is much con- neaed with a debility of the conftitution in general, and probably of the lymphatic fyftem in particular: the com- plaint firft fhewing itfelf by affections of the latter. This is evident from the nature of many of the caufes, and from fuch remedies as are found to prove moft ferviceable in the cure. Gentle mercurials are fometimes of ufe as refolvents in fcrophulous fweUings*; but nothing has fuch good effeas as the large ufe of peruvian bark. Chalybeate and fulphure- ous waters too, have frequently proved ferviceable: and a long ufe of mild faline aperients have been found benefi- cial. Cold bathing, and particularly in the fea, together with moderate exercife, is often of fingular fervice; as likewife change of air, efpecially to a dry climate. Until the general fcrophulous taint is removed, it is dangerous to heal the ulcers; all that fhould be done, therefore, fhould be, to give as free a vent to the matter as poffible, and to prevent the formation of finufes. The beft applications are the faturnine preparations: thefe remove that inflammatory complexion they affume when relaxants are employed; and tend much to prevent the fpreading of the fores. When, however, the ulcers become fwelled and pain- ful, and difcharge a very corrofive matter, we may fufpea a caries to be at the bottom of the fores. Nature muft then be affifted, where it is praaicable, by the removal of fuch parts of the bones as are moft difeafed, and have become loofe. But this cannot be done when the large joints are I affefted: * Compreffes dipped in a folution of fal ammoniac, in vinegar and wa- ter, and applied to the tumors before any inflammation appears, have been found ufeful. [ 66 ] affeaed: In that cafe, as amputation is not always advifea- ble, for fear of the difeafe returning, we muft trufl to na- ture for a cure. Here the general remedies, formerly men- tioned, fhould be diligently employed. I think I have feen cicuta have very good effeas in mending the difcharge from the ulcers, when joined with the bark. When it will be fafe to heal the ulcers, iffues fhould al- ways be introduced. Gentle compreffion has uncommonly good confequences in fores of this kind. CHAP. III. SECT. I. Of the Symptoms and Caufes of White Swellings of the Joints. THE term white fwelling has commonly been apr plied to fuch enlargements of the joints as are not attended with difcolouration of the integuments ; the only fymptoms which at firft take place, being a greater or lefs degree of fwelling, with a deep feated pain. In the pro- grefs of the difeafe, however, inflammation affeas all the adjoining parts, as well external as internal; and when this terminates in fuppuration, it is not uncommon for openings to be formed all around the difeafed joints. There feem to be two fpecies of this difeafe, entirely different in nature from each other. In the one, a cure is often in part, and fometimes wholly obtained; whereas the other is always beyond the reach of art. Swellings C 67 3 Swellings of this kind occur more frequently m the large than in the fmaller joints; thus, at leaft twice as many are met with in the knee and. ankle joints, as in all the reft of the bodybefides. § 1. Of the Rheumatic fpecies of White Swelling. This difeafe begins with an acute pain, which feems to be diffufed over the whole joint, and frequently even ex- tends along the tendinous expanfions of the mufcles. There is from the beginning, an uniform fwelling of the whole furrounding teguments in greater or lefs degree: but is al- ways fo confiderable as to occafion an evident difference in point of fize between the difeafed, and the found joint of the oppofite fide. A confiderable tenfion generally prevails; but there is feldom, in this period of the diforder, any ex- ternal difcolouration. The patient from the beginning, fuffers much pain from the motion of the joint; and, finding it eafieft in a relaxed pofture, keeps it generally bent; this often produces a rigi- dity in all the flexor mufcles, which is often afterwards with difficulty removed. If the difeafe is not now carried off, the fwelling augments gradually; and has fometimes ac- quired thrice the natural fize of the part. The cuticular veins become turgid and varicofe: the limb below the tu- mor decays confiderably in its flefhy fubftance, at the fame time that it frequently acquires an equality in point of thicknefs, by becoming cedematous; the pain now begins to be more intolerable, efpecially when the patient is warm ; and abfceffes form in different parts of the fwelling, and run in various direaions, but frequently without inter-com- munication. In thefe a fluauation is generally evident up- on preffure.—Thefe fweUings have a peculiar elaftic feel. When the colleaions of matter have an opening formed to them, they difcharge at firft a pretty good pus: this, however, [ 68 ] however, foon degenerates into a thin foetid ill-digefted fanies ; and has never any remarkable influence in reducing the fize of the fweUings. If the fores are not kept open by art, they foon heal up, and others are formed by colfeaions in different places ; fo that in fome cafes, the furrounding te- guments are entirely covered with cicatrices remaining after fuch ulcers. Long before this period, the patient's health fuffers con- fiderably: firft from the pain, which is often fo violent as to take away both fleep and appetite, and afterwards from the abforption of the matter. When the difcharge of matter commences, the effeas of its abforption begin to appear ; thefe are quick pulfe, night fweats, and weakening diarrhoea, which generally at laft carry off the patient, unlefs the difeafe is cured. I have had feveral opportunities of examining limbs af- feaed with white fweUings, that were amputated in very early periods of the difeafe, on account of the intolerable pain, and an apprehenfion of the complaints being incura- v ble. In all thefe inftanees the only morbid appearance, was a preternatural thicknefs of the furrounding ligaments, without any difeafe of the joint whatever. The degree of this enlargement did not appear always proportionate to the duration of the complaint. In an advanced ftage, it always was confiderable; and was generally attended by an effufion of a thick glairy matter into the furrounding cel- lular fubftance, which probably caufes the peculiar elaftic feel of the fwelling. The different abfceffes run in various direaions through this matter, without feeming to mix with it.—A great ma- ny fmall hydatids are alfo obferved in fome inftanees, in dif- ferent parts of the tumor—And, in the farther progrefs of the difeafe, all thefe together form a confufed mafs. All thefe appearances I have met with, without any con- comitant affeaion of the bones of the joint. When the complaint, C 69 ] complaint, however, has continued very long, the ligaments are deftroyed by the acrimony of the matter, which in con- fequence abrades the cartilages, and then renders the bones carious. The tendons are neither enlarged nor hardened. § 2. Of the Symptoms of the Scrophulous White Swelling. In this fpecies the pain is generally more acute than in the other; and inftead of being diffufed, is more confined to a particular fpot, moft frequently to the middle of the joint. The pained part appears fometimes to be no larger than a dollar. The fwelling is at firft commonly very in- confiderable. The leaft motion gives pain; hence a con- traaion of the limb is at length produced as in the other fpecies. As the difeafe advances the pain and fwelling in- creafe ; and an evident enlargement of the ends of the bones takes place. In procefs of time the tumor acquires the fame elafticity as occurs in the rheumatic fpecies ; varicofe veins appear— abfceffes are formed—On examination the bones are found carious, and parts of them are difcharged at the fores that are produced.—By the farther continuance of the difeafe, the conftitution fuffers in the femerhanner, as in the vari- ety firft defcribed. When joints are diffeaed in the firft ftages of the dif- order, the foft parts feem to be very little affeaed ; but in all that I have examined, there was conftantly obferved an enlargement either of the whole ends of the bones, or of their epiphyfes; frequently of thofe on one fide of the joints only; but in fome, both bones have been difeafed. This enlargement fometimes is the only morbid appearance; but generally, and always in the advanced ftages, the foft fpongy parts of fuch bones are found to be diffolved into a thin, fluid, fetid matter; and that in fome cafes without the cartilages being much affeaed. Thefe, however, are at length diffolved; and then the different C 70 J different hard and foft parts intermixing, exhibit an incon- ceivably confufed mafs. In the advanced flagc of the complaint the foft parts are generally affeaed. The ligaments become thickened, and the cellular membrane is filled with the fame glairy matter that is produced in the rheumatic white fwelling. § 3. Of the Caufes of White Swellings. The caufes of the rheumatic fpecies may be, fprains that particularly affea the ligaments of the joints, bruifes, lux- ations, and whatever can tend to produce inflammation of the ligaments. A rheumatic diathefis or difpofition is pro- bably alfo a principal caufe of this difeafe. For rheumatifm is known to attack particularly the ligaments, or other deep feated membranes, and more efpecially affeas the larger joints—Hydarthrus or white fwelling alfo occurs in the fame habits that are moft fubjea to rheumatifm, viz. the young and plethoric. That it is the ligaments that are firft affeaed in this difeafe is evident from the hiftory and diffeaions. From thefe we may conclude, that this complaint is at firft al- ways occafioned by an inflammation of the ligaments of the joints. And we may confider the different matters that are formed, to depend on the difference of parts affeaed in the courfe of the difeafe. The other fpecies of the diforder, from the fymptoms enumerated, and the appearances on diffeaion, feems evi- dently to be originally an affeaion of the bones ; the foft parts feeming only to fuffer in the progrefs of the difeafe from their conneaion with and vicinity to thefe. It fel- dom is the confequence of any accident; and the patient is feldom able to account for it. This difeafe is generally attended with known fymptoms of fcrophula; or the patient has had them at an earlier pe- riod C 7i 3 riod of life, or at leaft is of fcrophulous parents. From thefe, and the above defcribed circumftances, it is probable the diforder is of a fcrophulous nature. SECT. II. Of the Treatment of White Swellings. In the rheumatic white fwelling, as it is always at firft of an inflammatory nature, confiderable advantages are ob- tained in common, by the ufe of an antiphlogiftic courfe. The firft remedy which fhould be employed is blood-let- ting—This is moft effeaual if the blood is drawn immedi- ately from the affeaed part, by cupping, performed on each fide of the joint. At leaft eight or ten ounces fhould, if poffible, be difcharged at each time, and this fhould be repeated according to circumftances. When a fuffici- ent quantity of blood cannot thus be obtained, leeches fhould be had recourfe to. A fmall blifter fhould be immediately applied on the an- terior part of the joint; and the part afterwards kept run- ning until the wounds from which the blood was difcharg- ed, are fo far healed, that a veficatory may be laid on one fide and as foon as this is nearly healed another fhould be placed on the oppofite fide of the joint. By thus ap- plying them alternately to each fide, a conftant flimulus is kept up; which, in deep-feated inflammations, feems to have a greater effea than the difcharge produced from them. Cooling laxatives, at proper intervals, are alfo of ufe; and the patient fhould, in every refpecl, be kept upon a ftria antiphlogiftic courfe. From an attention to all thefe cir- cumftances the difeafe has frequently been removed. The [ 72 3 The inflammatory fymptoms being moftly gone, and while there are yet no appearances of the formation of matter, mercury, not given fo as to falivate, but merely to affea the mouth gently and to keep it fomewhat fore for a few weeks, I have fometimes known of ufe. The beft form of employing it in this cafe is by way of unc- tion— 5'ij. of a weak mercurial ointment fhould be rubbed into the part three times a-day ; and as the friaion may be very ferviceable, it fhould be continued an hour each time. By the French writers, falls of warm, and of cold water, on fweUings of this kind are much recommended. There is the greateft reafon to fuppofe, from the known relaxing powers of moifture when joined with heat, that a proper application, and particularly of warm emollient fleams may prove more ufeful than any other remedy. The friaion in the ufe both of warm and cold water has probably a confiderable influence; and the chief effea I think, can be attributed to that only in the latter cafe. I have fome- times feen it employed with advantage. Although by the ufe of thefe remedies, the difeafe is often entirely removed ; yet, in many inftanees, when the pain and fwelling are chiefly or entirely gone, it frequently happens, from the bent pofition in which the limb has been kept, that the ufe of the joint is entirely loft, and it contraas fuch a rigidity, that very great pain attends any attempts to move it. It has unfortunately happened that this contraaion has been generally attributed, either to an union of the ends of the conneaed bones, or to an infpiffation of the fynovia ; both of which are incurable. But from diffeaions we may confidently conclude, that except in the moft advanced ftate of the difeafe, the firft does not occur in one cafe in twenty; and that it is very doubtful whether the laft is ever produced. The [73 3 The immobility of the joint is confequently to be confi- dered as the effea of a contraaed ftate bf the flexor muf- cles, and tendons; which, in feveral inftanees, fome of which were thought to be of the worft fpecies of anchylo- fis, I have feen totally removed by the application of emol- lients. See chap, on Contratlions of the Limbs. After the formation of matter, no confiderable advantages can be expeaed from any of the remedies we have above recommended. In that cafe, the difcharge of the colfeaions fhould be made as foon as poffible, by the employment of the feton—This can eafily be effeaed, and fometimes has been the means of faving many fuch difeafed joints. Amputation fhould never be had recourfe to unlefs the patient's conftitution is fo much reduced, that there would be confiderable rifle from any farther delay. When the difeafe has deftroyed the ligaments, and per- haps the cartilages and bones of the joint, amputation is the only refource. See chap, on Amputation. All the above remarks, relate particularly to the rheu- matic white fwelling. With refpea to the more fatal fpe- cies, the fcrophulous, we can offer nothing fatisfaaory. When the fmall joints are affeaed, and the difeafed parts of the bones begin to caft off, a cure may be fometimes promoted by aflifting the efforts of nature; but in all the larger joints, it is not probable that any other refource than amputation will ever afford much relief. And even the effects of this can feldom be depended on as lafting; for while the fcrophulous taint fubfifts in the conftitution, the diforder will moft probably appear again in fome other part. On account of the violence of the pain, it is how- ever neceffary fometimes to run the rifk of this. When it does not appear advifeable to perform the ope- ration, we muft truft to palliatives. Of thefe, opiates in large dofes, by moderating the pain and procuring fleep, are generally the moft ufeful. The general remedies and diet proper in fcrophula, are alfo to be recommended. K CHAP. t 74 3 C H A P. IV. Of Sutures. THE intention of futures, is to unite parts that have been divided. The futures in prefent ufe are dif- tinguifhed into the true or bloody, and the falfe or dry. The true futures are the interrupted, the glover's, and the twijled; thefe are performed by the needle. The union of parts produced by the medium of adhefive plafters has been termed the dry future. SECT. I. Of the Interrupted Suture. This is the fpecies of future that has generally been made ufe of in deep wounds; but we fhall endeavour to make it appear hereafter, that it is not fo well adapted to fuch cafes as the twilled future. In order to a proper retention of the parts, in forming futures in general, it has ufually been confidered neceffary to carry the needle to the bottom of the wound, fo as to give no room for the accumulation of matter; and this has commonly been done by introducing it from without in- wards, and then from the wound to the fame diftance on the oppofite fide. But, the interrupted future is more neatly and eafily performed, by paffing both ends of the thread from within outwards, by means of a needle fixed on each. When they are carried through, the needles are to be C 75 3 be removed, and the threads remain untied, until all that are found neceffary are paffed. The number of ligatures muft depend chiefly on the ex- tent of the divided parts. One future has generally been faid to be fufficient for an inch of wound, but when muf- cular parts are cut tranverfely, a greater number in pro- portion to the extent of the fore will be neceffary. A li- gature fhould be introduced at every angle of a wound, however inconfiderable it may be. In paffing the ligatures it has been a rule to pierce the fkin at a diftance from the edges of the wound equal to its depth, in order to prevent them from cutting through the parts. But it is very feldom proper to make the fpace more than an inch, or lefs than half an inch. The form of the crooked needle proper for forming the interrupted future is delineated in plate vii. fig. 6. The fize of the needle, as well as the ftrength of the ligature, muft always be pro- portioned to the depth of the wound, and the retraaion of the parts. The ligatures ought nearly to fill the eyes of the needles ; and in order to make them pafs eafily, to render them durable, and eafily fufceptible of a flattened form, by which they are lefs liable to cut through the contained parts, they fhould be well waxed. While the furgeon is tying the threads, the lips of the wound fhould be preffed together by an affiftant. The ends of the ligatures are ufually carried twice through the firft noofe, to prevent them from flipping. This forms the furgeon's knot. The in- fertion of lint beneath or between the knots, as recommend- ed by fome, prevents them from being well made, and has little good effea. It is neceffary to tie the threads imme- diately above the wound, in order to give an equable fup- port to each edge of it. SECT. [ 16 1 SECT. II. Of the Studied Suture. The quilled future is formed by a quill, or piece of plaf- ter, rolled up into the form of a quill, and placed on each fide of a wound, one of which is included in the doubling of the ligature, and the other is preffed by the knot. This future has been ufed in very deep wounds, and fuppofed to give better fupport than ligatures alone, which fometimes cut through the parts; but it is evident that the threads muft make as great a preffure when the quills are ufed, as when they are not; and confequently, that this fpe- cies of future might with propriety be entirely laid afide. SECT. III. Of the Glover's Suture. The glover's future confifts in a feries of flitches connea- ed with each other, and continued in an oblique fpiral di- reaion along the courfe of the divided parts. The ufe of this future has been confined to wounds of the inteftines: but even thefe may be more perfeaiy united by the inter- [ rupted future. See chap, on Wounds of the Intejlines. It will therefore follow, that the glover's flitch is en- tirely unneceffary to a furgeon. SECT. £ 77 3 SECT. IV. Of the Twifed Suture. In making the twifted future, we unite divided parts by means of threads twifted around pins or needles pufhed through their edges. This future has feldom been employed, except in the hare-lip; but it is preferable to any other fpecies in all wounds that are not more than an inch and a half in depth, becaufe better calculated to retain the parts in contaa. In very deep wounds the interrupted future muft neceflari- ly be ufed, on account of the difficulty and pain that would attend the introduaion of pins to form the twifted future. The pins made ufe of for twifting the threads upon, fhould be flat, as in plate ix. fig. 7.; as the whole preffure falls upon them, and when thus made they are not fo apt to divide the parts as ligatures. Thofe ufually employed are of filver, with fleel points ; but as gold pins are not fo lia- ble to acquire a cruft by immerfion in fluids, and require no fleel points, they fhould be preferred. They ought, in general, to be from an inch to an inch and an half in length, of a proportionate breadth, and have heads for the fingers to prefs upon. In performing this operation, the divided parts muft be brought nearly into contaa by an affiftant, leaving only fuch a fpace as will allow the furgeon to fee that the pins are car- ried to a proper depth. A pin is then to be introduced on one fide externally, pufhed inwards to within a little fpace of the bottom of the wound, and carried through the oppofite fide, to the fame diftance from its edge that it was made to enter at on the other fide. The diftance at which the pin fhould be entered from the edge muft be determined by the depth of the wound, and the degree of retraaion of its fides, as in making the interrupted future. If the pins do C 78 3 do not pafs eafily, the inftrument termed porte-aiguille may be ufed to pufh them forward. The firft pin being thus paffed very near one end of the wound, and the parts flill fupported, a firm waxed ligature fhould be carried three or four times around and acrofs it, fo as to defcribe the figure of 8, and fufficiently tight to draw the lips of the wound into clofe contaa. The thread fhould then be fecured by a loofe knot, and another pin introduced. The ligature is now to be loofened, and applied to this pin as direaed for the firft, and others paffed at proper diftances, the whole length of the wound, all being conneaed by the fame ligature. A pin fhould always be placed near each end of trie fore, to prevent the feparation of its extremities. In large wounds the pins fhould be three-quarters of an inch dif- tant from each other; but in the fmaller, a greater num- ber in proportion to the extent of fore will be neceflary. When the futures are all formed, the wound fhould be covered by lint wet with mucilage, to exclude the external air. The introduaion of lint beneath the ends of the pins has a tendency to make them cut the parts. When they give uneafinefs, a piece of thin linen fpread with adhefive plafter will be better. I have never known the appli- cation of a bandage after this operation produaive of good effeas, but have often feen it occafion troublefome inflammation. In general, the pins fhould be fuffered to remain from five to feven days, according to the depth of the wound. But when the patient is unhealthy, a longer time may be neceffary*. As * In young healthy fubjecls the union is often completed in half the time; but perhaps the fafeft way is to leave the pins in the parts till a fmall degree of digeftion appears. C 79 3 As foon as they are removed, a bandage may be ufed with advantage, to fupport the newly-united parts. But perhaps ftrips of leather fpread with glue, applied to each fide of the cicatrix, and conneaed by ligatures, would be preferable. Of the dry future we fhall treat hereafter. CHAP. V. Of the Ligature of Arteries, and other artifi- cial means offopping Hemorrhagies. IN every wound, the firft circumftance to be attended to is the hemorrhagy. This is either produced from the large arteries, or by a general oozing from the fmaller veffels. In the firft cafe, a temporary ftoppage of the difcharge fhould be immediately attempted by com- preffion, until the permanent fecurity of ligatures can be obtained. In the head and trunk, the eafieft method of preffure is formed by lint or foft linen retained firmly on the mouths of the veffels by the hand or a bandage; or if the fuperior part of the veffels can be compreffed it anfwers better, as ligatures can then be applied with more eafe. When the wound is in the extremities, and compreffion can be made on the fuperior part of the artery, it fhould immediately be done by means of the tourniquet. Plate iii. fig. 5. ' Previous [ 8o 3 Previous to the application of the tourniquet, a cufhion, three inches in length, and one and an half in breadth, fhould be placed immediately above the principal artery, and well fecured by two turns of a roller. Over this roller the ftrap of the tourniquet is to be firmly fix- ed, the fcrew being on the fide of the limb oppofite to the cufhion: one turn of the fcrew is generally fufficient. See plate and explanation. As the ancients were ignorant of the ufe of the tourniquet and of ligatures, they endeavoured to remove hemorrha- gies by applying aaual cauteries or hot irons to the large veffels, and lint covered with ftyptic powders, to the fmaller. But thefe often failed. Even lately, agaric, cha- lybeate folutions, and the mineral acids have been much recommended. Thefe in many cafes do not produce the defired effea. When ligatures can be well applied, they invariably fucceed; and in the larger veffels fhould alone be depended on. Various methods have been ufed for tying arteries. The common praaice at prefent is, by means of a curved needle to pafs a ligature of fufficient ftrength around the mouth of the veffel, including a quarter of an inch of the contiguous parts : but, as tying the nerves and mufcles often produces not only partial but general fpafms, and always a great deal of pain, it is advifeable to include the artery only in the ligature, by employing forceps, or rather the te- naculum, Plate vii. fig. 5. In very deep wounds the needle may be neceffary ; but fuch cafes rarely occur. Ex- perience from repeated comparative trials has convinced me, that the mode recommended is, as fecure as that by the needle ; and when it is ufed the ligatures come away much fooner, generally at the third or fourth dreffing ; which is often of very great advantage. I have feen inftanees of the ligatures remaining for weeks when the needle was employed, and fome cafes in which they were at laft cut away by the furgeon. The C 8i ] The forceps do not anfwer well in tying fmall arteries; they might therefore, with propriety, be entirely laid afide, as the tenaculum or hook is equally applicable to the large and fmall arteries. The manner of ufing it is as fol- lows : In order to detea the arteries to be tied, the tourniquet muft be loofened, and as foon as the largeft artery is dif- covered, the furgeon fixes his eye upon it, and immediate- ly again tightens the tourniquet. An affillant then forms a noofe in the ligature, and placing it over the end of thevef- fel, the operator pufhes the point of the tenaculum thro' the fides of the veffel, and pulls as much of it out as he thinks fhould be included in the furgeon's knot now to be made by the affiftant. For greater fecurity a fecond knot fhould alfo be formed. In making the knots, a very fmall addition to the force requifite for reftraining the hemorr- hagy, is fufficient. In this manner all the arteries that can be diftinguifhed fhould be fecured: For fatal hemorrhagies have fome- times been produced from very inconfiderable veffels, when the patient has become warm in bed. Lofs of blood, fear, or cold, often occafion fuch a retraaion of the fmal- ler arteries, that it is difficult to detea them :—To ef- fea this, the tourniquet fhould be loofened, and the wound well wafhed with a fponge and warm water ; and if the patient is faintifh, a glafs of wine or fome other cordial fhould be given. As in fome inftanees we are unable to tie arteries by means of the tenaculum, we fhould be provided with nee- dles of various forms and fizes. Thofe ufed in forming the interrupted future are very well adapted to the tying of arteries. In ufing the needle, it fhould be introduced, armed with a ligature, at the diftance of a fixth or eighth of an inch from the artery, pufhed to a depth fufficient for retaining the thread, and carried one half round the veffel. L It [ 82 3 It muft now be withdrawn, and being again pufhed for- ward till it has encircled the mouth of the artery, is then to be pulled out, and a knot formed on the ligature as al- ready direaed. Hemorrhagies to an alarming degree are frequently pro- duced in extenfive wounds by a general oozing from the furface of the fore ; and fometimes it is with difficulty they are fupprcffed. They feem to proceed from two very dif- ferent circumftances : ift. In robuft habits, either from too great a quantity of blood, an excefs of tone in the veffels, or a combination of both; or 2dly. And more frequent- ly, in relaxed debilitated habits, from a diffolved ftate of the blood, a want of tone in the veffels, or a concurrence of both thefe. In healthy conftitutions, the difcharge of blood from the fmaller veffels of wounded parts is commonly foon remo- ved by the contraaion of thefe veffels, and the difcharge of a glutinous fluid from them, which is diffufed over the furface of the wound : But when it continues in fuch de- gree as to fhew a morbid ftate, it is to be attributed to one of the caufes abovementioned. In robuft habits relief is to be obtained by opening a vein; or perhaps more ef- feaually by untying one of the principal arteries of the part and fuffering it to difcharge freely ; by keeping the patient cool ; giving him cold acidulated drinks ; obliging him to avoid motion, particularly of the part; covering the wound with lint; and by applying a bandage over it. In all thefe cafes, and particularly when violent fpaf- modic affeaions fupervene, a large dofe of opium is one of the moft effeaual remedies, and fhould be exhibited as foon as the patient has been bled and put to bed. When we have reafon to fuppofe the difeafe is fupported by the fecond fet of caufes mentioned, a generous diet, and a free ufe of Port, Madeira, or other good wines, fhould be al- lowed i C 83 1 lowed; the patient fhould be kept cool; mineral acids, particularly the vitriolic, muft be given ; reft of body en- joined ; and opiates, to obviate pain or fpafm, liberally ad- miniftered. Together with thefe general remedies, particular dref- fings, adapted to the ftate of the fyftem, fhould be applied. Dufting the parts with ftarch or wheat flour, or gum arabic in fine powder, has been ufeful in all flates of the body, but particularly in that of debility. In this cafe, lint moiften- ed with tinaure of myrrh, traumatic balfam, and other fti- mulating applications, are very ferviceable. When thefe do not prove effeaual, an equable preffure by a bandage, or the hand applied ever the dreffing, will feldom fail*. * This laft mode of preffure is much the beft, and has fucceeded in fome aneurifms, where it could be made immediately upon the orifice of the wounded artery. CHAP. [ 84 3 CHAP. VI. Of Blood-letting. SECT. I. Of Blood-letting in general. IN all general affeaions where blood-letting is confider- ed neceffary, the blood is difcharged by an opening made in an artery or vein. The former operation is^ cal- ? led arteriotomy; the latter phlebotomy. In local affeaions, ^ particular benefit is often afforded by dividing a number ■ of the fmaller veffels of the part difeafed; this is termed . topical bleeding. i We fhall firft confider phlebotomy. The choice of a vein | in this operation, muft be determined by the particular circumftances of the patient. The veins from which blood is ufually drawn, are thofe of the arm at the flexure of &e cubitus or fore arm, the jugular veins, and thofe of the ankles and feet. On certain occafions, blood is alfo taken from the veins of the hands, tongue, and other parts. In blood-letting in general, as the pofition of the pati- ent has fome influence on the effeas of the operation, it fhould be precifely fixed. When fainting is likely to be induced, and we do not wifh to rifk it, an horizontal pof- ture is to be preferred; but if we expea advantages from the fainting, the patient fhould be placed erea. The part to C 85 3 to be operated upon fhould- be fo fituated, as that the principal light of the apartment may fall direaiy up- on it: and the furgeon ought always to be feated ; as he will then bleed with much more fleadinefs and nicety than if he ftands*. When the patient is properly fixed, a ban- dage fhould be applied to the member to be operated upon, to produce an accumulation of blood in the veins ; but not fo tight as to obftrua its paffage in the correfponding ar- teries. Various inftruments have been invented to bleed with ; but there are only two now in ufe : the lancet and the phleme. The phleme is placed immediately on the part to be cut, and by means of a fpring is ftruck fuddenly into the vein. Its inconveniencies are, that we muft regulate the depth to which it is to go, before we apply it;. on which account, if the vein lies deeper than fuppofed, we may not reach it; and there is danger of its wounding arteries, \ qr other parts beneath the vein, if it fhould go too farf. j Thefe difadvantages do not attend the ufe of the lancet, / and therefore it certainly ought to be preferred. The lancet fhould be fpear-pointed—it then enters the integuments with little pain •, and forms an opening in , them very little larger than the orifice ia-the vein, which readers it an jafy matter to flop the difcharge.—Thefe ad- vantages are not derived from the broad-fhouldered lan- cet in common ufe. The ligature having been made for a fhort time to pro- duce fome fwelling in the veins, that vein is to be fefeaed which * This depends upon habit—thofe accuftomed to operate ftanding will perform with more eafe to themfelves, than if they were feated. f Notwithftanding thefe obvious objections, the phleme is very uni- verfally ufed here, among the bleeders, in preference to the lancet; and even fome medical practitioners employ it. I have very feldom heard of any material bad effects from itj ufe—never but of one cafe of aneu- rifm. C 86 } which rolls lefs than the others on being preffed with the finger, even if it fhould be fomewhat deeper than thofe near it—Veins that lie contiguous to arteries and tendons fhould, if poffible, be avoided ; although a dextrous ope- rator may often open them with perfect fafety. When a vein is made choice of, the furgeon, if he is to ufe the right hand, grafps firmly the member, an inch and an half below the part to be operated upon with his left, and makes fuch a preffure on the vein, with the thumb, as will interrupt the communication between the inferior part of it, and the part above the thumb, and will render the teguments fomewhat tenfe. The lancet being bent to ra- ther more than right angles, is then to be taken between the thumb and fore-finger of the right-hand of the opera- tor, and leaving one half of the blade uncovered, he refts his hand on the remaining fingers, and then pufhes the point of the lancet into the vein, and carries it forward in an oblique direaion, until the orifice is fufficiently large. The point ought neither to be raifed nor depreffed, left it fhould wound parts unneceffarily. The inftrument is now to be withdrawn, and the left hand removed as foon as the cup for receiving the blood is applied. While the blood is flowing, the member fhould be kept in the pofition it had when the incifion was made; otherwife the fkin may flip over the orifice in the vein, obftrua the difcharge, and produce ecchymofis. If the wound is made longitudinally, it does not admit of a free difcharge ; and if acrofs the vein, it is difficult to heal. The fize of the orifice muft depend on the circum- ftances of the difeafe for which the bleeding was ordered. In general, when the fpear-pointed lancet is ufed, an eighth of an inch will be fufficiently large; but when we employ the common lancet, a quarter of an inch will not be too much. It C 87 3 It fometimes happens that the blood is not freely dif- charged, either from faintifhnefs, or from the opening in the fkin receding from that in the vein. In the firft cafe, it will be proper to admit a ftream of air into the apart- ment, to give fome wine or other cordial, and have the patient placed in a horizontal pofture. If the blood does not then flow as we wifh it, the part fhould be put into a variety of pofitions, the mufcles fhould be thrown into ac- tion by moving fomething in the hand, if the arm is ope- rated upon; and if the pulfe is feeble in the inferior part of the member, we fhould loofen the ligature. As foon as a fufficiency of blood is drawn, the com- preffion fhould be taken off, and if the difcharge does not then ceafe, the thumb fhould be applied above, and the fore-finger below the orifice, and it being well wafhed and cleared of blood, its fides fhould be brought exaaiy to- gether, and there retained by a ft rip of adhefive plafter. This will generally be fufficient; if it is not, it will be pro- per to apply a linen comprefs over the plafter, and fecurc both with a roller. The wound will commonly heal by the firft intention, or without the formation of pus; but troublefome confe- quences fometimes enfue. Of thefe the moft material are thrombus or ecchymofis; wounds of arteries, nerves, or tendons contiguous to the vein; and inflammation of the internal coat of the vein operated upon. SECT. II. Of a Thrombus or Ecchymofis. A thrombus is a fmall round tumor produced by extra- vafated blood infinuating itfelf into the cellular membrane. When this fwelling is more diffufed it is termed an ecchy- mofis. C 88 3 mofis. In bleeding, it is commonly induced by the orifice in the fkin receding from that in the vein. Immediately on the appearance of fuch fweUings the ligature fhould be removed, and again applied, as foon as the limb is brought into the pofition it had during the operation. Should not this fucceed in difperfing the tumor, or at leaft in pro- curing a free difcharge of blood, the ligature muft again be taken off; and if the neceffary quantity of blood has not been drawn, another vein fhould be opened. Thefe fweUings in general go off of themfelves ; but if they do not, they may often be difperfed by the applica- tion of compreffes wet with brandy, or a folution of fal ammoniac in vinegar. If thefe have not the defired effea, the tumor fhould be laid open, the blood taken out, and the wound then healed in the ufual mode. SECT. III. Of Wounds of the Arteries. The only certain method of knowing whether an ar- tery is wounded through the vein, in bleeding, is to com- prefs the vein above and below the orifice; if the artery is wounded, the difcharge will then continue, or be increafed; if it is not, it will ceafe. The flow of blood being per fal turn, is a fallacious criterion, becaufe it may happen from a vein lying immediately above an artery. As foon as we are certain of an artery being thus wound- ed, as much blood fhould be fuffered to flow as the ftate of the body will admit of, and the wound fhould then be clofed by adhefive plafter; reft fhould be enjoined, and the body kept cool; gentle purgatives muft be given, and blood-letting repeated occafionally. By thefe means, the fyftem will be relaxed, and we fhall have fome chance of healing [ 89 3 healing the wound. If this is not accomplished, the effufi- on of blood forms a fpecies of aneurifm. It has been the common praaice in wounds of the ar- teries, to apply immediate and flrong compreffion, by means of compreffes and bandages ; but it is evident that this, from the obftruaion it gives to the paffage of the blood, according to its degree, muft either increafe the he- morrhagy by producing an increafed aaion in the artery, or caufe a gangrene in the parts below. SECT. IV. t Of Wounds in the Nerves and Tendons from Bleeding. These accidents arife from carrying the lancet through the back part of the vein; and may be avoided by keep- ing the point of the inftrument in a ftraight direaion*, in- flead of depreffing it after it has entered the cavity of the vein. If immediately on the introduaion of the lancet the pa- tient complains of exquifite pain, we may reft affured that either a nerve or tendon has been wounded. In fome cafes, by proper management, the pain will gradu- ally go off entirely without any bad confequence whatever. At other times, however, the pain foon increafes, a fmall degree of fwelling takes place ; the lips of the fore become fomewhat hard and inflamed ; and in the courfe of about twenty-four hours from the operation, a thin watery ferum begins to be difcharged at the orifice. If relief is not foon obtained, thefe fymptoms generally continue nearly in the fame flate for two or three days longer. At this time, the pain becomes greater, and in- M ftead * See Se