MECHANICAL OBSTRUCTION IN DISEASES OF THE UTERUS. BY GEORGE F. HULBERT, M.D., OF ST. LOUTSTSttr.' FROM THE MEDICAL NEWS, December 20, 1890. Reprinted from THE MEDICAL NEWS, December 20, 1890. MECHANICAL OBSTRUCTION IN DISEASES OF THE UTERUS.1 BY GEORGE F. HULBERT, M.D., OF ST. LOUrS,'*MO. My observations of and experience with the dis- eases of the uterus in which mechanical obstruction, or its congener, stenosis of the canal, is considered to be the malady is so at variance with the consensus of medical opinion and practice, that I wish to make it a matter of record and open the door to criticism and correction, if such are deserved. It may be somewhat startling to many of those men whose reports of cases and operations relating to the subject under consideration so frequently appear in our medical journals, when we say that in more than ten thousand women coming under our care in hospital and private practice, a large proportion of whom suffered from uterine disease, we have not seen a single case which satisfied us that mechanical obstruction existed or was the dis- ease, although the phenomena supposedly attendant upon that condition were frequently observed; and that in over three hundred autopsies in which the 1 Read at the sixteenth annual meeting of the Mississippi Val- ley Medical Association, Louisville, Kentucky, October 8, 9, and 10, 1890. 2 HULBERT, pelvic contents and conditions were carefully ex- amined, we have not found a single case which positively demonstrated that during life mechanical obstruction existed -that condition which has oc- cupied so much of the time and attention of gyne- cologists, and has been the fons et origo of so much operative procedure and instrumental paraphernalia. Such being our declaration, it becomes incum- bent upon us, in explanation, to present the reasons for " the faith that is in us." In doing so, we shall consider the subject under the following heads : 1. The normal or natural order of things, as related to structure and function. 2. The abnormal, pathological, or unnatural order of things, as related to structure, and the possibility or impossibility of, or interference with, the per- formance of function. 3. The phenomena usually considered as due to "mechanical obstruction" and their accepted ex- planation. 4. Our criticism and reconciliation of inconsis- tencies, based upon the facts and phenomena ob- served by us during life and in the dead-house. 5. Conclusions. First. We may question if menstruation, as ob- served to-day, is a perfectly normal or natural phenomenon as far as it relates to the quantity of fluid discharged. Reasoning by analogy and from the purely physical standpoint, it certainly seems a strange straining of that universal uniformity of law and order in nature, that in the highest mam- malian this particular element in the functional phenomena should be so greatly and unnecessarily MECHANICAL OBSTRUCTION. 3 overdone. But it seems from the testimony at hand that such is the fact; that at the menstrual period in women we do have a more or less free discharge of fluid, instead of what seemingly should be a simple elimination or excretion. The conclusion, therefore, which we must reach, is that the organ which we are considering must be competent to discharge fluids. The reason that the uterus is composed of involuntary muscle is at once plain to any one who considers its other peculiar func- tion, gestation ; but the reason for its peculiar form, the arrangement of its cavities, the complicated in- terlacement of muscular fibres, the dual nervous supply, and the delicately-poised position in the body is not so evident. In our search for a reason for these things, it occurred to us that the uniformity of law and order in nature might be a possible ex- planation, and that in the physical laws and condi- tions governing the discharge of fluids would be found the answer to the query. Investigation in this direction led to the conviction that the appli- cation of the conic frusta to containers presented the most perfect conditions in order that the greatest velocity and quantity of discharge of fluids be attained. The laws and principles involved in this particular domain of physics presented a striking adaptation to the uterus, and seemed to offer a clear explanation. By reference to Fig. i this application may be seen. We have four apertures of exit, at D, E, C, and A. At the aperture of the Fallopian tubes ; at the internal os or sphincter, extending down to the line B; and at the external os extending into the vagina, we 4 HULBERT, see the principle of the conic frusta applied with peculiar perfection. As to form, we see this at the internal os, C. It is also to be observed that that Fig. i. part of the entire canal which approaches each aperture is more or less perfectly tubular in form, MECHANICAL OBSTRUCTION. 5 thereby assuring a column of liquid above and pres- sure in the axis of exit. We also find that each aperture is provided with a well-developed muscular sphincter, covered with a thin, closely-adherent mucous membrane, which insures the even closure of the lips of the apertures, save at the external os, where other principles come into play, namely, that of aspiration by the contact of the os with the vaginal mucous membrane, and the elastic play insured by the uterine ligaments, the movements of respiration, and the general movements of the body. In estimating the capacity of the normal uterus by means of the above principles of hydrodynamics, it was found that the uterus was capable, with one- fourth of an inch aperture at the point of exit and one inch depth of cavity, with the resultant pres- sure of the column of liquid contained therein, of discharging 0.64541 cubic inch per second, or 38,624.4 ounces during the twenty-four hours. Re- ducing the diameter of the ap rture to one-thirty- second of an inch, we find a capacity equal to 603.493 ounces for twenty-four hours. In men- struation the average flow for twenty-four hours is from three to five ounces of fluid with a temperature of ioo° Fahr, and a specific gravity of 1-055. This gives the uterus a capacity to discharge about 600 ounces more than it is required to discharge, with an aperture of one-thirty-second of an inch. It is also necessary to recall the peculiar arrange- ment of the muscular elements of the uterus, namely, longitudinal, oblique, and transverse muscular fibres intimately interlaced, establishing conditions which, 6 HULBERT, in the presence of proper innervation and nutrition, insure the certainty of play of force. With peculiar strength is the fact of the dual nerve-supply, namely, a direct spinal supply to the cervix and a ganglionic supply to the body of the uterus, brought to mind in our application of these principles. The cervix, responsive to immediate reflex influences at the in- ternal sphincter, especially concerned in permitting exit and entrance under proper conditions; the body, under ganglionic innervation, concerned in the wonderful phenomena of creative energy, in the to-and-fro play of its forces annuls sufficient of the necessary antagonism to establish equilibrium in the performance of function, and menstruation becomes an unconscious experience in the life of women, save to the sense of sight. In the circulatory arrangement we see a still fur- ther application of our principles, in that the quan- tity of fluid is governed by a power inherent in the organs, so that in the presence of equilibrium of all else the supply and discharge are under perfect con- trol. As a last point under this head, we will recall the rhythmical intermittent discharge of the fluid during' menstruation, dependent upon the physiological action of the uterine circulation. It may be well termed the evidence of a uterine respiration, so to speak, by which the life of function is maintained. Second. From a pathological point of view, the conditions accepted as being the cause of mechanical obstruction are those that produce narrowing or closure of the uterine canal. These so far as de- scribed are flexions, conical cervix, pinhole os, and MECHANICAL OBSTRUCTION. 7 congenital or acquired partial or complete stenosis, the latter being synonymous with atresia. Some consider displacements without distortion of the canal as mechanical obstruction, but the presence of the open canal makes such claims inconsistent. However, those who have taken the latter position have made progress, and, in reality, their inconsis- tency has brought them, nearer the truth. The condition of flexion of the uterus has gener- ally been considered the typical one for mechanical obstruction; and we are presented with the flexed rubber tube as illustrating the condition. But this fails to illustrate the conditions as they actually exist. The manner in which a flexion is brought about is, we believe, in perfect accord with mechanical laws. Given that vicious constitutional condition, of which the local expression is debility of the uterine tissue and its supporting ligaments, called softness by Graily Hewitt, without which the de- velopment of a flexion is impossible, the first step is an excessive amount of blood in the parenchyma of the organ and its adnexa. This means lack of mus- cular tone and increased weight, causing the uterus, as a whole, to rest on the posterior and lower part of the pelvic floor; or, if the conditions are so for- tunate, on the lower uterine ligaments. The descent persisting and increasing, owing to the angle at which the cervix meets resistance, or to pressure on the fundus, the cervix or body must move either forward or backward, and the result is a flexion. This is a matter of time ; there is not sudden violent bending of the uterus, as occurs in the rubber tube, 8 HULBERT, and the degree of bending is determined by the con- ditions of the uterine tissue. This bent position having been produced, a process of atrophy at the At A is seen the indentation where the normal tissue has atrophied. B and C show the hypertrophy in the posterior wall! concavity of the angle, and of elongation and hyper- trophy at the convexity, at once begins, and /ar/ /axsvzwith the bending the atrophy and hypertrophy proceed, so that in the process, when completed, that factor which is the essential cause in producing closure in the rubber tube, namely, the V-shaped wedge of tissue at the convexity of the angle, is not 'present. This is shown by the accompanying cut (Fig- 2). The hypertrophy of the posterior wall is due, no doubt, to the constant efforts exerted to accomplish the function of menstruation under the changed conditions, and also by the constant irritation pro- MECHANICAL OBSTRUCTION. 9 duced at the point of impact on the floor of the pelvis. The atrophy of the anterior wall at the angle is in accordance with the well known effects of pressure and interference with nutrition. The disappearance of this wedge of tissue in the anterior wall at the site of the angle, in the final rearrangement and adapta- tion for function, results in the longitudinal and oblique fibres, anteriorly, having instead of two points of departure in contracting, as at the fundus and extremity of cervix, three points, namely, from fundus to angle, and from the angle to the extremity of the cervix, the ultimate result being the same in either case-pulling forward of the anterior segment of the tissue at the site of the angle. The posterior segment would follow, as it does in the rubber tube, on the simultaneous contraction of the longitudinal and oblique fibres, but for the interposition of the lateral segments, which does not occur in the rubber tube. Thus it is seen that with a fairly coordinate action of all the fibres in any particular transverse plane of the uterine body closure of the canal is simply impossible. Any angle in the direction of the canal must be more or less straightened, this result being dependent upon the area of uterine tissue brought into action. A perfect en masse contrac- tion of the organ must produce more or less straight- ening and patency of the canal dependent upon the amount of force exerted. This is illustrated by Fig. 3. To this antagonism of forces we can attribute the fact that in the most acute flexions the canal is not 10 HULBERT, bent at an angle, but maintains the direction of the segment of a circle. Extreme degree of flexion-450 : O, showing the atrophy in the anterior wall at the site of flexion ; M, O, A, points of departure on the contraction of longitudinal and oblique fibres in the anterior wall. The interposition of the lateral wall between the anterior segment at O and the posterior at B makes it impossible for the inner surfaces at A and B to come in apposition, save by a domi- nant contraction of the sphincter fibres. In our examinations to determine the degree of flexion we frequently deceive ourselves, and speak of acute angles. As a matter of fact, it is rare that we meet with a flexion more acute than a right angle, and in an acute-angled flexion during life we not only would be sure to find the fundus in the position of an anteversion, but the os would be toward the meatus urinarius. Fig. 4 illustrates what would be present in a right- angle flexion : If the central line, D B (Fig. 4), of the fundus was brought forward, and placed on the line C B, Fig. 3, we would have the fundus about in the normal position in the body. Now, moving the MECHANICAL OBSTRUCTION. 11 central line of the cervix forward so that it rests on B, F, we would find that the prolongation of this line would make its exit at the anterior edge of the anus. This would represent a flexion with a right angle. Now place D B on MB (Fig. 5> 12 HULBERT, the central line of the cervix on B F, and we have an angle of 450. In this case a prolongation of the central line of the cervix would pass out through the posterior commissure of the vulva. Fig. 5 shows an extreme degree of flexion, which is found only in the minority of cases. The proof of the disappearance of the tissue at the concavity of the angle of flexion is found in autopsies, and is demonstrated by straightening the bend and com- paring the anterior and posterior walls. We have seen some specimens in which the healthy tissue at the concavity was only one line in thickness. In order that the rubber tube should accord with the existing conditions, it is necessary to select one corresponding in the thickness of its walls and in its calibre with the normal uterus at the internal sphinc- ter, one which is elastic, one in which there is some means of producing the effects of the longitudinal and oblique fibres, and, lastly, one in which a suffi- cient amount of the wall at the concavity of the angle shall be removed corresponding to the absorbed and atrophied tissue at the site of the angle in the de- formed uterus. This done, the bent rubber tube will in a fair degree illustrate what takes place at menstruation in a flexed uterus. The action of the longitudinal fibres, as far as the anterior wall is concerned, can be produced by passing a few threads through the calibre of the tube, fixing it in the angle desired, which is usually not more acute than a right angle, and making traction on the threads in the line of each arm of the bent tube. It will be found that the obstruction even MECHANICAL OBSTRUCTION. 13 with this imperfect arrangement will be overcome, and that water will flow through the tube. This is illustrated by Fig. 6 : Fig. 6. The upper illustration shows the prepared tube ; at A, V-shaped wedge of the anterior wall removed. The lower illustration re- presents the same tube, bent at a right angle, and the effect pro- duced by traction on the threads in the line of each arm of the bent tube. The arms are firmly fixed in position in any sustain- ing apparatus, as a glass tube is slipped over and held by an assistant. Fig. 7. The closure on bending at B is readily understood, and the effect of removing the wedge-shaped piece of the anterior wall at A, as well as the influence of the longitudinal threads, is possibly better appreciated by the comparison. 14 HULBERT, Fig. 7 illustrates the usual faulty method, save that the tube is of the proper dimensions to use in the above experiment. From the foregoing we conclude that in the abnormal deviations of direction which are found in flexions, nature in her conservatism still utilizes the principles and agencies present in the normal state, and thereby perpetuates the operation of natural laws and insures the performance of func- tion. Only by this conception are we able to account for the phenomena of normal menstruation so fre- quently found, certainly in fifty per cent, of women who have well-marked flexions. We have frequently seen women in whom it was possible to pass into the uterus only a small wire probe, who had at no time suffered from inconvenience during the men- strual flow. Upon the other conditions productive of mechan- ical obstruction there is this observation to make, namely, that at times there exists the capacity to dis- charge fluid blood, save in only one condition- atresia. All that the uterine canal can justly be called upon to permit to pass through it is fluid blood. If the passage of clots, mucous plugs, shreds of membranes, etc., are the evidences needed to establish the conditions for mechanical obstruction, then we are, indeed, undone. We respectfully sub- mit that such a demand is unreasonable, illogical, and unscientific. We conclude, therefore, that the passage of fluid blood is positive proof that there exists a capacity in all the above conditions, save that of atresia, for the performance of function. MECHANICAL OBSTRUCTION. 15 Third and fourth. Such being our conclusion, how do we account for the symptoms usually ascribed to mechanical obstructions, namely, pain, intermit- tent and scanty flow, relief from pain when the flow is present, and inability to pass the uterine sound ? The most radical of those who claim that flexions produce mechanical obstruction, freely ad- mit that where menstruation is normal and painless obstruction is not present. Stenosis being the con- dition considered necessary, by the "obstruction philosophy," in the absence of the diagnostic symp- toms mentioned above, there is, consequently, no stenosis; hence these diagnostic symptoms must be explained. We have seen from what has been presented the importance of that harmonious, perfect, involuntary, and unconscious rhythm of circulatory, muscular, and nutritive action found in health. As the dom- inant energizing factor we must look to the inherent quality of nutritive and nervous capability, and to this alone; and in grasping the full meaning of this we must go back to the quality of protoplasm before our position becomes rational. This is a universal principle so frequently lost sight of by us as gyne- cologists, that it is no surprise to see so much error and disappointment in our therapeutics, be they surgical or otherwise. We must go to the nervous system, especially the sympathetic, for the all-governing factor: to nutri- tion, as a whole, we must go for stability of function. The nerve-tone coupled with the resultant nutritive activity and power, both impressed, under favorable environment, with the capacity for a higher stand- 16 HULBERT, ard, determines what shall be the future of every organism or part thereof. A woman born with and maintaining a standard degree of health will never be cursed with any of the conditions we are considering. But in those who are born without the standard, or who, by the vicissitudes and accidents of life, depart from per- fect health, in proportion to the deviation we will find the liability to and acquisition of these condi- tions. In these deviations from the standard degree of health we find lowered nerve and nutritive tone, manifested by irregular and erratic innervation, re- sulting in irregu'ar, incoordinate action, increased irritability, irregular circulation and muscular action, pain, spasm, and relaxation, alterations of secretion, rapid exhaustion, slow recuperation, imperfect re pair, insuring debility, fatigue, pain, and disorder in the accomplishment of function. These are the real factors in the dysmenorrhoea of so-called mechanical obstruction. These, and not stenosis, are the disease. In the functional antagonism between the cervix and the body of the uterus we find the immediate cause of all the symptoms attendant upon mechanical dysmenorrhoea. Irritation or dilatation of the cer- vix produces contraction of the cervix. This physi- ologically and anatomically demonstrable fact, which, if sought for, is always found antedating and associated with mechanical dysmenorrhoea, when followed to its reasonable and logical conclusion, proves that mechanical obstruction, as at present generally accepted, does not exist save in that con- dition termed atresia. The constitutional condition means increased MECHANICAL OBSTRUCTION. 17 local irritability and lowered nutrition. This begets irreg-ular and spasmodic muscular and circulatory action, with altered excessive or scanty secretion and excretion. The excessive flow, the blood-clots, the membranes, and the mucous plugs are due to the influences mentioned, and their expulsion produces severe suffering. Such cases are used by some as an argument in support of the idea of mechanical dysmenorrhoea, especially when a flexion is present. It is unnecessary to answer such arguments. It would be perfectly consistent for these men to as- sume mechanical obstruction as a disease, in the delivery of a foetus. But given menstruation with fluid blood as the substance to be expelled in a woman who presents the symptoms of mechanical dysmenorrhoea, what facts will aid us in the present discussion? Excluding atresia, it matters not what the local condition is, we find the general devia- tion from the standard degree of health. A fat and apparently well-nourished woman may present symptoms at her menstrual period similar to those presented by another woman in the opposite condi- tion of general health. In the first instance, inner- vation, motor power, is at fault; in the second, the fault is in both innervation and nutrition. In both the local conditions are alike. Now, take either of these women and place her under methods of treat- ment that will allay irritation, produce coordinate action, and improve the general health, and we find that without any local treatment all the symptoms indicative of mechanical dysmenorrhoea disappear, and still the flexion, pinhole os, elongated cervix or stenosis, remains. Let the woman return to 18 HULBERT, the original diseased condition, and the symptoms of mechanical dysmenorrhoea again appear. Further- more, in the worst cases, in which the flow is usually very scanty, we find that in spite of the persistent stenosis, as they approach the standard degree of health the flow increases and the suffering decreases and eventually disappears. Manifestly, we must look elsewhere for the cause of the symptoms, and we find it in lowered nutrition and increased irrita- bility, expressed by hypersesthesia and erratic mus- cular and circulatory action. It is nerve-ache, muscle-ache, nerve tire, muscle-tire. It is the cry for quietude, harmony, and rest from the ceaseless and persistent wants of the physiological rhythm of forces. That the local condition in its development has no influence on the systemic we do not affirm. In the progress of every case the time arrives when the local condition, by reflex influences, becomes a very important element in the process: first, from general to local ; second, from local to general, until the poor sufferer cries out in agony, afraid to move, afraid to laugh, afraid to lie down ; tenderness and pain in all parts of her body, and in constant fear of the monthly onslaught of what should be to her an unconscious relief. This is not enough, it seems, but she must be further accused of carrying around with her a disease called "mechanical ob- struction," and be subjected to sponge-tents, and incision and divulsion of the cervix, followed by the use of a stem-pessary. Especially bearing upon the interpretation of the pain in conditions of supposed mechanical obstruc- tion, we desire to direct attention to a condition in MECHANICAL OBSTRUCTION 19 which the pain is of the same character and in which mechanical obstruction cannot be present, namely, the "after-pains" of parturition. We are of the opinion that as far as the location, character, and manner of onset of the pain are concerned, there are no differential features between the pain of mechanical dysmenorrhoea and the "after-pains" of labor, yet in the presence of only fluid blood severe "after-pains" frequently occur. There being no stenosis after a parturition, the severity of " after- pains " in the absence of blood-clots is considered dependent upon nervous, nutritive, circulatory, or muscular influences, even by the most radical sup- porters of mechanical obstruction in menstruation. In considering the question of spasm of the inter- nal sphincter as a factor in producing the phe- nomena of mechanical obstruction, we are impressed with the desperation of many in striving to retain the mechanical idea of dysmenorrhoea. Correctly understood, this frequent and ever-ready action of the internal sphincter serves but to establish our position in antagonizing the mechanical idea. The presence of the spasmodic element is proof positive of unnatural and incoordinate muscular action, as well as increased local irritability. This, coupled with the antagonism existing between the cervix and body of the uterus,-readily explains why during menstruation, rhe spasmodic action should occur, and also why there is no flow until the spasm is relieved. In spasmodic or neuralgic dysmenorrhoea the menstrual flow is almost ml. This is not due to a damming back by the spasmodic closure at the sphincter, but is due to the fact that there is no 20 HULBERT, menstrual fluid in the cavity of the uterus, and it is only when coordinate action is accomplished that blood exudes from the endometrium. This is readily proven by the introduction of a tube into the uterine canal during the menstrual period, insuring beyond a doubt patency of the canal. The diminution or disappearance of pain when the flow is established is now readily understood, when we say that it is due to the rhythm of forces finally accomplished, to nervous, muscular, and cir- culatory factors, within the tissues, and not to the forcible expulsion of retained fluid. The failure to pass the probe or sound is a mere matter of diagnosis and dependent upon the hand that manipulates it. Finally, we appeal to post-mortem investigations. Any one who has labored in the dead-house, inves- tigating the pathology of those conditions which are considered active factors in the production of mechanical obstruction will meet with one stub- born fact, namely, that the conditions found after death are far different from those that would be expected from the severity of the symptoms during life. Consider, for instance, endometritis, and in the dead-house the specimen, macroscopically, is hardly distinguishable from one obtained from a subject who had never during life suffered from such a disorder. Microscopically we find the dif- ference, and in the vast majority of cases are forced to conclude that this difference is more a func- tional than organic one. Take also any speci men and study the subject of stenosis of ihe canal, and how often, unless there is stenosis from scar- tissue in the mucous tissue lining the canal or MECHANICAL OBSTRUCTION. 21 congenital atresia, will you find a contraction that fluid blood would not find its way through; certain it is that fluid blood will travel through the capil- lary system, and the uterine canal, save in atresia, has a diameter equal to at least several capillary vessels. We also find in post mortem examinations that the uterine canal, even in the presence of great deviations in surrounding structures, or extreme dis- tortion and displacement of the organ, is free from acute angles, and that the cavity is tubular, especi- ally at the site of the internal sphincter. These facts are readily proved by sections in any direction, and are readily accounted for if we accept the in- fluence of the muscular elements and correctly interpret the mechanical laws at work in the form and structure of the uterus in their relation to the performance of function. In the attempted demonstrations of the existence of mechanical obstruction by its supporters, the fact that they were dealing with a dead organ seems to have been lost sight of; for in no other way can we explain the usual methods of attempting to prove mechanical obstruction during life by forcing a life- less flexed uterus into a greater degree of flexion, for even dead as it is it will not remain in the forced position. It would seem unnecessary to remark that pickled specimens are not suitable for demonstration, either affirmative or negative, yet they are frequently presented as showing the state during life. The therapeutic measures which are successful in relieving and curing mechanical dysmenorrhoea demonstrate beyond all doubt the correctness of 22 HULBERT, our position. And in using the expression thera- peutic measures, we wish it distinctly understood that we exclude all local, surgical, or mechanical treatment to relieve the supposed stenosis of the canal. The use of reconstructives, such as good, palatable food, the elegant gluten and malt prepar- ations, and the hypophosphites and bitter tonics, for the purpose of restoring the standard nutri- tion ; the employment of narcotics, anodynes, anti- spasmodics, such as opium, compound spirit of ether, antipyrine, viburnum opulus and viburnum prunifo- lium, alaetris farinosa, helonias dioica, cimicifuga, Scutellaria, laterifolia, and gelsemium; the valuable anti-congestive drug, hydrastis; the coordinating muscular tonics, ustilago maydis and quinine; and last but not least, electricity, are attended with results eminently successful. The intelligent and persistent use of these means will, in the absence of atresia, cause all the phenomena of mechanical obstruction to dis- appear, while the local deviation, as far as form and displacement are concerned, may remain. The local state, as far as secretion and function are concerned, will be restored to a normal condition. Furthermore, it is a matter of daily observation, that all surgical and mechanical methods of treating dysmenorrhcea which are not assisted by pronounced improvement in the systemic, nervous, and nutritive forces of the patient are ineffectual. We respectfully submit the following conclusions: i. That in the natural order of things we find the uterus in form and structure endowed with a capacity for the performance of the function, menstruation, so far in excess of any legitimate demand, that with MECHANICAL OBSTRUCTION. 23 a diameter of the canal of one-fourth of an inch at the sphincters the excess is 7724.8 times the de- mand, and with a diameter of one-thirty-second of an inch the excess equals 120.7 times the requirement. 2. That in the pathological conditions considered essential for mechanical obstruction we find that the conservation of force so regulates the condi- tions that this capacity is not abolished, but persists in an eminent degree, so that in the presence of the normal physiological energy the function is accom- plished, unless there is atresia. 3. That the phenomena considered as dependent upon mechanical obstruction are not due to the forcible expulsion of retained fluids through the uterine canal, but are produced within the tissues, and are dependent upon disturbed rhythm of physi- ological forces evolved by abnormal innervation, muscular action, and circulation. 4. That the demand upon the uterus for the passage of blood-clots, membranes, mucous plugs, uterine sounds, sponge-tents, uterine dilators, etc., in order that the diagnosis of mechanical obstruc- tion may be made, is not only vicious in the extreme, but irrational, illogical, and unscientific. 5. That the correct and rational interpretation of the testimony offered by symptomatology, path- ology, and therapeutics, removes mechanical ob- struction from the domain of gynecology as a demonstrable fact, save in atresia uteri. 3026 Pine Street. THE MEDICAL NEWS. 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