I j«EX TRACTS f v A K. X O TT S J O tT n IV A Ij H ' I TO I FRANCIS' " I GALVANIC and ELECTRO MAGNETIC PROCESS OF I (Ertrorting Ccctt) witljout pain. | ► / '*C 1$ / gw I ' PHILADELPHIA: j INQUIRER PRINTING OFFICE, 121 SOUTH THIRD STREET, | > '* * 1858. 1 ! . _ EXTRACTS FROM xr zl n. i o rr s <rouiitixrykiijs \ IN RELATION TO FRANCIS' GALVANIC and ELECTRO-MAGNETIC PROCESS OF (£rtrMting CActij mittjout pain. PHILADELPHIA: INQUIRER PRINTING OFFICE, 121 SOUTH THIRD STREET, 1858. EXTRACTS From the July Number, 1858, of the Dental News Letter, edited by J. D. White, M. D. D. D. S., and J. R. McCurdy, D. D. N GALVANIC PROCESS. This seems to be a new application of* galvanism, and one that is likely to be of some importance to the dentist. We cannot see how it could be well applied to any other operation in surgery than to extracting teeth. Our atten- tion was first directed to it by Mr. J. B. Francis, dentist, but we gave it no serious consideration, as we regarded it as one of the thousand expedients of the day to attract attention in the newspapers. But we were attached to a sub-committee of the scientific committee of the Franklin Institute, to investigate its claims ; under these circumstances, we gave it some attention. The manner of applying it has already been made public. Most persons suppose that there is a shock experienced in applying it, or that it is painful to the tooth ; these objections are not correct. We have applied it in many cases, and the pain was considerably less than in the ordinary way, in all except one case. One patient, a lady about twenty-five years of age, had three or four roots extracted, without applying the galvanism, and suffered great pain. We applied the current, and she still suffered severe pain. The teeth were hard to extract. After extracting three teeth, we sent the 4 patient to a dentist who had been very successful in its use, but she suffered there as much as with us; so it is clear, that in this case galvanism, as at present applied, was of no use to that patient; but in every other case it did lessen the pain. Some patients ask, when they observe us leave the mouth, whether we have taken out the tooth or not, as they are not sensible when the tooth left the socket, although they know that we had put the forceps on the tooth, and that an effort at extracting had been made. We sent a great many patients to Dr. Wilkinson and to Dr. Francis, and they all gave a satisfactory report of their success. We sent a small boy to Dr. Wilkinson, and when he returned, he said that it did not " hurt him in the least." A young lady called on us a few days ago to get a set of teeth, who had ten large teeth extracted by Dr. Francis. She said they did not ''hurt her" in the least. These teeth were extracted without lancing the gum. It may do in some cases, but we approve of lancing the gum in extract- ing teeth. The great question to be decided is, does this process take away the terror of extracting a tooth? the pang of dislodging a tooth from the socket ? With us it is our decided opinion that it does. Although some patients experience some pain, they say they would not be afraid to get another extracted. It is a constant remark, "Well, I would not have another extracted the old way." There is no danger in applying the galvanic current in any case, as in chloroform or ether. Many persons tell us that they tried ether once, but would not try it again. It does not relieve the patient from a dread of a second application. We consider this of more importance than the alleviation of pain. There is another important matter connected with the galvanic process. The patient, no matter how many teeth may have been extracted, does not feel exhaused after the operation, 5 as when the extraction is done without the galvanism, or under the influence of ether or chloroform; it leaves no sequences. We have conducted our experiments against prejudice; but what we have witnessed thus far, we are satisfied with, and would recommend it to the consideration of dentists. J. d. w. THE APPLICATION OF GALVANISM IN THE EXTRACTION OF TEETH. For some months past, there has been in this city certain persons professing to extract teeth without pain, by the use of Galvanism, and about which we have received many letters of inquiry. Sufficient interest was felt in the matter to induce the appointment of a committee by the "Franklin Institute" of Philadelphia, also one by the " Pennsylvania Associa- tion of Dental Surgeons," and from the report of the former we shall make some extracts, and the latter we hope to give entire elsewhere.* We had been of the opinion that the effect of the application of an electric current to the tooth, would not lessen the amount of pain usually experienced in extrac- tions, but simply change the character of that pain, yet causing more or less suffering; and we found similar opinions were entertained by one or more occupying prominent positions in the profession, consequently we had given but little attention to the matter; but now, from the increasing interest manifested by the profession as evidenced by personal and written inquiries made of us, and the position it has assumed, gives it an import- ance that requires some notice in our journal, and we propose, therefore, to give such facts in connexion with it as we have been able to collect. *This report has not yet been made. 6 Any agency that promises the alleviation of pain is to be sought after, and such an one is peculiarly desirable in the extraction of teeth; for how many there are whose health is impaired by retaining in their mouths diseased teeth and roots, rather than submit to the pain of extraction. If, therefore, by this process, the pain, if not entirely annulled, be only diminished, and that without the risk and dread sometimes attending the employment of the ordinary anasthetics, much every way is accomplished ; and for these very important considera- tions we trust the profession will test the matter tho- roughly and report results. The application is somewhat as follows:-The nega- tive pole or wire of the ordinary electro-magnetic machine -which is a graduated battery-is attached to the forcep or handle of it,* and then placing the metallic handle of the other pole in the hand of the patient; by this means a circuit is at once formed, on the forceps coming in con- tact with the tooth. An additional appliance is used in the form of a small spring footboard, which interrupts the current, but by pressure of the foot upon it, the circuit is at once formed. This interruption is said to be desirable until the forcep is placed upon the tooth, when the circuit is formed and the extraction made at once. One gentleman remarked to us that he often permitted the current to flow for a second or two before the attempt at extraction. It is given by another as his experience, that in a protracted operation, the prolonged pain would over- come or neutralize the effects of the electric current, and that in such cases, no exemption is afforded the patient by its use. We witnessed the extraction of some ten teeth and roots from the mouth of an intelligent but nervous lady, *One gentleman we saw operate, had the attachment made by drilling a hole through the end of one handle of the forcep, through which he passed a small copper wire hook, to which the flexible cord of the battery was attached. 7 whose features we watched closely throughout the opera- tion, and who remarked that she " suffered very little pain from their extraction," and when complimented on her courage, said, in substance, that " she could not lay any claim to courage, for her endurance must be wholly attributed to the galvanism, which rendered the opera- tion comparatively a painless one." A peculiarity was noticeable in this case, viz :-The entire exemption from pain in the extraction of a molar tooth, the surrounding parts of which were very sensi- tive from being in a highly inflamed condition, and which rendered this exhibition of its effects very satisfactory. One thing, however, we could not fully understand, which was the shrinking of the patient on the application of the forceps, for, we reasoned, if no pain, why this indication of fear ? But this was clearly explained to us in a sub- sequent experiment by another operator, (when we wit- nessed the extraction of several teeth and roots, the patient-a nervous female-asserting that she suffered very little pain,) by having the application made to our own mouth. The sensation, when the current was com- pleted, being anything but agreeable, and somewhat simi- lar in pungency to the application of fire, or a jet of flame to the living tissue, when we could readily understand why the pain of extraction would be neutralized to a very great extent under this influence, and were at once reminded of our former opinion of its merely changing the character of the pain. Still, had we any teeth requiring extraction, we should certainly test the bat- tery, in the hope that we would be the gainer thereby. From the report of the committee appointed by the Franklin Institute, we extract as follows :- " One hundred and sixty-four teeth were extracted in the presence of the committee. * * * * " The committee is satisfied from the observation and experience of its members, that in a large majority of 8 cases of extraction with this apparatus, no pain whatever is felt by the patient. * * * * * " To test the question whether the effect might not be simply mental, the circuit was broken without the patient being aware of it, when the usual pain was experienced, although, in the same patient, and on the same occasion, teeth had been removed while the current was flowing, without causing pain. * * * * * " The sensation produced by the passage of the current is not painful, it being so adjusted as to be just percepti- ble to the patient. The committee believes its use to be entirely without danger, and not likely to be followed by any unpleasant after effects. * * * The operator requires no new instruments except the battery and coil. * * * * * "As to the theory of these very singular and unex- pected results, the committee does not express an opininion; of the facts it is fully satisfied." A gentleman out of the city, who felt a great desire to test it, reports :- 1 have extracted about 30 teeth since I returned, by the "Galvanic Process," with the most satisfactory results, some saying that it did not 'hurt a bit,' (to use their own language.)" In the Southern Medical and Surgical Journal for June, we find a communication from I). S. Chase, M. D., D. D. 8., detailing his experience in extracting " more than fifty teeth" with electricity, from which we extract as follows :- " The First Case in which I tried it, I removed seven teeth, all firmly set-five molars and two cuspidati or eye teeth. In extracting the first tooth, too much electricity was applied, and the patient complained of pain from the shock, but not from the removal of the tooth. In the second tooth too little was applied, and the tooth itself gave pain. After this, we were able to regulate the quantity, so that neither the electricity nor the extraction of th^ tooth gave much pain. Patient not at all nervous, and frequently expressed herself highly pleased with the operation. The feeling expe- rienced during the extraction of the teeth, as she 9 expressed it, was a benumbing sensation about the tooth, which appeared to be attached only to the gum. " Second Case.-Extracted six teeth. Patient some- what debilitated from previous suffering with her teeth, and quite nervous. Suffered considerable pain during the operation, but would not allow one to be extracted without electricity. " Third Case.-Extracted four teeth. Patient suffered but little pain. " Fourth Case.-Extracted a molar tooth, that had been previously broken, for a highly intelligent gentle- man from a neighboring village. He was much pleased with the operation, and was very enthusiastic in his praises of electricity as applied to Dental Surgery. " Fifth and last Case, that I will report at present.- Extracted ten teeth for an elderly lady. Expressed no fear or pain during the operation, and seemed to treat the affair as a mere trifle, which might be attended to any morning, without much inconvenience. " The general expression by those who have tried it, seems to be decidenly in favor of electricity in extract- ing teeth. In some of the cases mentioned above, the gums were lanced by the same process, by connecting one pole of the battery with the handle of the lancet, while the patient held the other-the hand of the operator being protected by a silk glove." As will be noticed in the above extract, a glove is necessary on the hand of the operator to prevent his receiving a portion of the current, or the intervention of a napkin between the operator's left hand and the pa- tient's mouth may be sufficient. The suggestion of connecting the lancet with the bat- tery is a good one, and worthy of attention. We have been informed, we may say in conclusion, that a patent has been obtained for this application of gal- vanism, and that it is the intention of the proprietors to dispose of office rights. About this, however, we need say nothing further now, than we regret any restriction to its universal use, should be placed upon a discovery claiming to be such a blessing to the human race. J. r. m'c. 10 EXTRACT From The American Journal of Dental Science, of July, 1858, edited by Chapin A. Harris, M. D., D. D. S. and A. Snowden Piggot, M. D. EDITORIAL DEPARTMENT. Local Anaesthesia by the Application of an Electric Cur- rent.-Many, if not most of the readers of the Journal, have doubtless heard of this novel method of producing local anaesthesia, and its application in the extraction of teeth. It was brought to the notice of the Senior Editor about two months ago, by one of the agents of Mr. Jerome B. Francis, of Philadelphia, the inventor, with the request that he would give it a fair trial. Hav- ing consented to do so, he requested the agent to place in the infirmary of the Baltimore College of Dental Surgery one of the small galvanic batteries which had been gotten up for the purpose, and, at the time appointed for the experiment, a number of persons, having decayed and aching teeth, presented themselves for the purpose of undergoing what they had been led to believe would be a painless operation, and in nearly every case their hopes were seemingly realized. Between thirty and forty teeth were extracted by Dr. Arthur, late Professor in the Philadelphia Dental College. The experiment at the College was continued two afternoons; on the second day the Senior Editor was not present, but Dr. Arthur informed him it was quite as successful as on the 11 first, and with a view of ascertaining how much the imagination might influence the patient, he, in the case of a boy, who wished to have two teeth extracted, ap- plied the electric current while removing the first; the lad affirmed that he suffered no pain, but in the removal of the second it was not applied, and the pain occasioned by the operation was so great, that he screamed lustily. The apparent success of these experiments, induced the Senior Editor to apply the invention of Mr. Francis in his private practice, and the result thus far has cer- tainly been very satisfactory-a large majority of his patients, for whom he has extracted teeth, having assured him that they experienced no pain while under- going the operation, and, as a general thing, those who did suffer, stated that the pain was much less than what they usually suffered under the operation. The anaesthetic effect of the electric current seems to be different in different individuals. When the tooth can be grasped and extracted without the instrument coming in contact with the gum, the operation has been appar- ently completely successful, but when it is pressed against the surrounding soft tissues, the entire current of the electricity does not pass through the tooth, and we presume it is for this reason, that the operation is not then successful. How it is that local anaesthesia is thus produced we cannot understand, but that it is, at least in a large majority of cases, seems to be well established, and wishing to give our readers all the information we possess upon the subject, we subjoin the following report of the Philadelphia Franklin Institute, and to -which, it will be perceived, are attached the names of two dentists well known to the profession. As the method of applying the electrical current is described in this report, it is not necessary for us to repeat what is there said upon the subject. 12 Hall of the Franklin Institute, Philadelphia, April 8, 1858. The Sub-Committee on Science and Arts, constituted by the Franklin Institute of the State of Pennsylvania, for the promotion of the Mechanic Arts, to whom was referred for examination the method of extracting teeth, invented by Mr. Jerome B. Francis, of Philadelphia, Pa. REPORT. That the object of this invention is the painless ex- traction of teeth. The method is simple. It consists in attaching the extracting instrument by means of a flexi- ble conductor to one pole (preferably the negative) of an ordinary electro-magnetic machine, while the patient grasps the metallic handle attached to the other pole. An interrupted electrical current thus traverses the body of the patient and the extracting instrument. The intensity of the current is previously graduated by with- drawing the piston of the coil while the patient grasps both the forceps and handle, until it is just distinctly perceptible, and the circuit through the tooth is not com- pleted until the moment at which extraction is to begin. In regard to the efficacy of the process, the Committee has the following testimony :- 1st. 164 teeth were extracted in the presence of the Committee, a report of which cases is herewith sub- mitted. 2d. Members of the Committee have experimented independently with the apparatus. The report of one member who has had it in use four weeks, and extracted between four and five hundred teeth with it, is also sub- mitted. The Committee is satisfied, from the observation and experiment of its members, that in a large majority of cases of extraction with this apparatus, no pain whatever is felt by the patient. 13 To test the question whether the effect might not he simply mental, the circuit was broken without the patient being aware of it, when the usual pain was experienced, although, in the same patient, and on the same occasion, teeth had been removed while the current was flowing, without causing pain. In the less successful cases, the teeth were broken and diseased below the level of the gum, and the pain, in adjusting the forceps previous to the completion of the circuit and the extraction, considerable. The sensation produced by the passage of the current is not painful, it being so adjusted as to be just percepti- ble to the patient. The Committee believes its use to be entirely without danger, and not likely to be followed by any unpleasant after effects. The whole apparatus is cheap, the operator requires no new instruments except the battery and coil, and the application demands no more time, and scarcely more trouble than the ordinary method. In these respects its use contrasts favorably with that of general ansesthetics, which are troublesome and tedious in their application, and not free from danger, or the employment of freezing mixtures to the jaw, for the pur- pose of producing local anaesthesia; a process which cannot be recommended as either harmless or efficient. The Committee believes the employment of electricity in the manner and for the object indicated, to be original with Dr. Francis. It is true, that the heat developed by the passage of a considerable current through fine platinum wire, has been employed to cauterize ulcers of the throat, and to destroy the nerves of teeth. There is obviously, however, no parallelism in these cases. The use of the electrical current in neuralgia presents more analogy; in these cases, however, the current is used for a long period, and with the object of inducing a change in the morbid state of the parts, rather than as 14 a means of removing pain at once; whereas, to be effec- tive in extraction, the current must be applied at the moment of extraction ; if allowed to flow through the tooth for a very short time before the operation, its effect is diminished or lost. As to the theory of these very singular and unex- pected results, the Committee does not express an opinion ; of the fact it is fully satisfied. In view of the importance of the discovery, the Com- mittee recommends to Mr. Francis, the award of the Scott's medal and premium. All of which is respect- fully submitted. [Signed,] Wm. Hamilton, Actuary. Philadelphia, April 3d, 1858. To the Sub-Committee of Science and the Arts, of Franklin Institute, on Francis' Invention: Gentlemen: I have deemed it my duty to submit to you the fol- lowing statement, for fear I might not be able to attend at your meeting. When I first heard of Mr. Francis' invention, my impression of it was very unfavorable ; more, perhaps, for the reason that I did not understand how the elec- tricity was applied. Having heard from several of my patients that teeth had actually been extracted without pain, I felt it my duty to try some experiments with it. The first experiment I tried was on three teeth of my son's. I attached one of the poles of the electro-magnetic machine to the forceps, and fitted on the tooth. 1 then had my son grasp firmly a handle attached to the other pole of the machine, and at the same time I drew the tooth. The rod of the electro-magnetic machine had been previously so adjusted, that when my son (the patient) grasped the handle in one hand, and the forceps in the 15 other, he could only feel a slight and pleasant sensation of electricity. The experiment was entirely successful, the tooth was extracted (my son says) without pain. I was just as successful with the other two, and also on some teeth which I extracted from my servant girl. I have up to this time, extracted with this process between four and five hundred teeth, and have been successful with ninety-five per cent of them. This process has, of course, entirely changed my first impression of the invention. I have now the most ex- alted opinion of it, and would not extract teeth without its aid upon any account. When a patient has more than one tooth to be ex- tracted, I find it saves me much time, for, by the old way, when I had extracted one tooth, I found it very difficult to persuade the patient to have another pulled, which sometimes consumed a great deal of time. By this process, I can go on pulling, as witnessed in the case recorded in my book as No. 3, in which four stumps were extracted in forty (40) seconds, and in No. 4, four teeth were extracted in fifteen (15) seconds, and waited only fifteen seconds, and then extracted two more in ten seconds. Case No. 6, had five teeth pulled in 30 seconds. Case No. 11, had five teeth extracted in 35 seconds, after an interval of thirty seconds, had six in thirty seconds more, and after an interval of thirty seconds, had two more in eight seconds, and after an interval of two and a half minutes, had one more incisor, making 14 in all. I also found, contrary to my first impression, that teeth diseased at the root could be extracted with but slight pain, and sometimes without any, and without any disagreeable feeling from the current, as witnessed in case No. 25 ; a lady, twenty-five years of age, had three teeth taken out, one of them very badly diseased at the root. She exclaimed, Oh ! that don't hurt 1 and so with several 16 other cases. There is sometimes an after-pain in extract- ing diseased teeth. It occurs immediately after the tooth leaves the socket; it is probably caused by the cold air coming in contact with the diseased part thus exposed. Teeth extracting is the most unpleasant part of den- tistry, and I am happy to state that, by my use of this process, I have been saved much of the unpleasantness occasioned by giving my patients so much pain. A young man had a tooth extracted by me yesterday, he said he had always a great difficulty in having his teeth extracted, but with this one he said he felt no pain. He was quite delighted and thanked me; something, he said, he had never done to a dentist before. Numerous instances of the same kind have occurred in my use of this invention. I have found that the hemorrhage is in no degree increased by this process, and I have heard of no person who experienced any sub- sequent pain or inconvenience. In no case have I found the use of this invention in any way objectionable. Very respectfully, yours, &c., B. Howard Rand, M. D. W. S. WILKINSON. Franklin Peale, Esq. J. Aitken Meigs, M. D. The report of the Committee on file in the Franklin Institute is signed by B. Howard Rand, M. D. Franklin Peale, W. H. Hazard, M. D. J. Aitken Meigs, M. D. Henry Hartshorne, M. D. J. De Haven White, M. D. Wm. S. Wilkinson, Edward Townsend, 1). D. S. The exclusive right to the application of electricity for the production of local anaesthesia in the extraction of teeth, has been secured to the inventor, Mr. Francis, as will be seen by the following schedule and letters patent: Eds. 17 The Schedule referred to in these Letters Patent, and making parts of the same. To ALL WHOM IT MAY CONCERN : Be it known, that I, Jerome B. Francis, of the City of Philadelphia, and State of Pennsylvania, have invented a new and useful improvement in instruments for remov- ing teeth; and I do hereby declare the following to be a full and exact description of the same, reference being- had to the annexed drawing, making part of this specifi- cation, which represents a perspective view of my im- provement. My improvement consists in combining with a common dental forceps an electro-magnetic machine, in such man- ner that a wire from a negative pole of the machine shall form a metallic connection with that part of the forceps that grasps the tooth, and that the positive pole of the machine shall be connected with the patient's hand by a metallic connection. The handles of the forceps, which are held by the operator, are better to be insulated with gutta-percha, or similar non-conducting substance. In the accompanying figure, A represents an ordinary electro-magnetic machine, with the battery, B, attached. D represents the ordinary dental forceps. A wire, C, passes from the negative pole, P, of the electro-magnetic machine to the point, d, of the forceps, where a close metallic connection is made. On the inner side of the forceps, at the point d, a small metallic cup is placed, and a small copper stem projects from the opposite side, e, of the forceps. As the parts f and g of the forceps close upon the tooth where it is surrounded by the gum, the induced current from the electro-magnetic machine passes through the wire C, and across from d to e, and thus applies itself around the whole tooth in the vicinity of the nerves, and so affects also the nerves, rendering them temporarily insensible. The patient, or person operated on, must hold in one of his hands the extremity 18 of the other wire, II, so as to complete the circuit through his body. 1 represents the hands of the operator grasp- ing the forceps, and K the hand of the patient grasping the wire passing to the positive pole of the machine. The electro-magnetic machine has a sliding rod, by which the induced current may be varied in intensity. The intensity of the current to be passed through the patient's tooth should be graduated, by observing in advance how much he can conveniently bear when he grasps the extremity of the wires H and C in each hand. A little practice will enable the dentist to determine this readily. The electro-magnetic machine, A, is of the ordinary form employed for medical purposes, and consists of a battery of one cell, a primary coil and inducing coil, a small electro-magnet for breaking and closing the circuit through the wires C and II and the patient's body. Any other form of electro-magnetic machine may be employed. I have described above, particularly, the machine frequently called an electro-magnetic machine, and which is used for medical purposes. There are several other forms of machine, sometimes classified as electro-mag- netic, or magneto-electric, which are known to be equiva- lent in their action on the nervous system to the one above described-such, for example, as the double helices, or coils composed of two coils of wire, one surrounding the other, one being a quantity helix, or coil, and con- nected with the battery, and the other an intensity helix, or coil, and to be connected with the body of the patient. Instead of using a little electro-magnet break-circuit in the first helix as shown in the drawing, a clock-work break-circuit, or electrotome, may be used, or a rasp may be used, in connection with the aid of an assistant, for breaking and closing the circuit ; so also there are several forms of magneto-electric machines in which permanent magnets are used, to induce, by mechanical action, a magneto-electric current in a coil surrounding a revolving 19 soft iron armature. In all these cases the same peculiar effect on the nerve of the patient's tooth would result if either of these machines were combined with the forceps, inasmuch as they are all well known to be ecpiivalents in applying electricity to the body for medical purposes. A direct circuit from the battery might also be combined with the forceps, and either with or without t he aid of an interposed break-circuit the same effect would take place to a great degree, although the use of such a bat- tery, of the proper intensity, would probably be found much more inconvenient than the magneto-electric (or as they are sometimes called, electro-magnetic,) machines above named. Instead of a metallic conductor, to connect the electro- magnetic machine with the forceps, any other kind of conductor might be used-or the operator's hands might be used for one conductor. I prefer to connect the nega- tive pole of the machine with the forceps; but this is not indispensable, as the positive pole will also answer. The little pieces, f and g, are not indispensable, because the forceps itself conveys the current very rapidly to the tooth, around the whole body of the tooth. Having thus described my improvement, what I claim as my invention, and desire to secure by Letters Patent, is the combination of the electro-magnetic machine, or its equivalent, with the dental forceps, for removing teeth without pain; arranged and operating substantially in the manner above described. J. B. FRANCIS. Witnesses, J. H. B. Jenkins, Charles D. Freeman. ISSUE No. 20,390. TO ALL WHOM THESE LETTERS PATENT SHALL COME : Whereas, Jerome B. Francis, of Philadelphia, Pa., has alleged that he has invented a new and useful Improve- ment in the Method of Extracting Teeth, (he having 20 assigned his right, title and interest in said Improvement to William Harper^ Jr. of said Philadelphia, and said Harper having re-assigned the same to said Jerome B. Francis, and the said Jerome B. Francis having assigned the same to James J. Clark, of said Philadelphia,) which he states has not been known or used before his appli- cation; has made oath that he is a citizen of the United States ; that he does verily believe that he is the original and first inventor or discoverer of the said improvement, and that the same hath not, to the best of his knowledge and belief, been previously known or used ; has paid into the Treasury of the United States the sum of thirty dollars, and presented a petition to the Commissioner of Patents, signifying a desire of obtaining an exclusive property in the said Improvement, and praying that a Patent may be granted for that purpose. These are therefore to grant, according to law, to the said James J. Clark, his heirs, administrators or assigns, for the term of fourteen years from the twenty-fifth day of May, one thousand eight hundred and fifty-eight, the full and exclusive right and liberty of making, construct- ing, using, and vending to others to be used, the said improvement, a description whereof is given in the words of the said Jerome B. Francis, in the schedule hereunto annexed, and is made a part of these presents. In Testimony Whereof, I have caused these letters to be made patent, and the seal of the Patent Office has been hereunto affixed. Given under my hand, at the City of Washington, this twenty- fifth day of May, in the year of our Lord one thousand eight hundred and fifty-eight, and of the Independence of the United States of America the eighty-second. JACOB THOMPSON, Secretary of the Interior. Countersigned and sealed zvith the seal of the Patent Office. J. HOLT, Commissioner of Patents. 21 Twelfth Meeting of the American Association for the Advance- ment of Science. General Session, Tuesday, May 4th, 1858. The Association was called to order by the President, and the minutes of Monday's proceedings read and approved. Dr. C. P. Williams read a paper on the production of local Anaesthesia, by a novel application of current elec- tricity. Though much has been done by Morse, Cooke, Wheat- son, Bain, Henry, House, and others, in the application of electricity to the arts, very little has been done in this respect for Physiological and Pathological science. The investigations of Matteucci and Raymond have been directed chiefly to the elucidation of the electricity of the body; those of Duchenne and Golding Bird have had in view the therapeutic uses of this agent. But the inquiries into this latter field are just beginning to open out into a new channel. A number of highly interesting experiments lately carried on in the city of Philadelphia, have developed the remarkable fact, that electricity can be applied with great advantage as a local anaesthetic agent. The drugs generally used to produce anaesthesia are, as is well known, troublesome and tedious in appli- cation, and not free from danger. Mr. Jerome B. Francis, of Philadelphia, (a dentist by profession,) has met with great success in the application of the electric current, to prevent pain in extracting teeth. His method for using the current is briefly described in the report of the committee appointed by the Franklin Institute of Philadelphia, to witness and investigate these experiments; a copy of which report is herewith submitted. The operations consist in attach- ing the extracting instrument, by means of a flexible conductor, to one pole of an electro-magnetic machine, while the patient grasps the metallic handle attached to 22 the other pole. An interrupted electrical current thus traverses the body of the patient and the extracting instrument. The intensity of the current is previously graduated by withdrawing the piston of the coil, while the patient grasps both the forceps and the handle, and thus secures a current that will not be unpleasant. [From the Baltimore American of May 5th, 1858. Office rights to use this Invention will be sold for $100, for the fourteen years for which the patents have been issued. In order to make the payment easier, we will sell on the following condition :- Right to use the invention for six months will be sold for $30-the purchaser to have the privilege of buying the right for the remainder of the time for which the patents have been issued, for $70 more. The purchaser will be furnished with complete appa- ratus with instructions, accompanied by a correct litho- graph, showing the operation of extracting a tooth by this process. Any further information may be had by addressing JAMES J. CLARK, Assignee and Patentee, Box 1885 Philadelphia Post Office. Thos. L. Vanderbeck is general Agent, and is vested with power of Attorney to sell Rights and protect the interests of the invention. JAMES J. CLARK.