[From the Proceedings of the Connecticut Medical Society, May, 1874. | SMALL-POX AT SOUTH WINDHAM, CONN. By ASH BEL WOODWARD, M.D., OF FRANKLIN, CONN. SMALL-POX AT SOUTH WINDHAM, CONN. The small-pox which, with almost unexampled severity, scourged the village of South Windham, Conn., during the winter of 1873-4, was marked with features which commend themselves to the attention of the profession. In a community of barely three hundred inhabitants there were about one hun- dred and thirty cases. The disease was introduced from abroad early in December and became generally prevalent towards the close of January, the contagion having been diffused by the free commingling of the people before its existence was suspected. The writer was first called in, Sunday, February 1st, and dur- ing the next six or seven weeks visited the village daily. A majority of the cases presented the ordinary symptoms only. The premonitory fever, accompanied by intense pain in the lumbar region and obstinate vomiting, ushered in the attack, and was fol- lowed in due order by the appearance of pimple, vesicle and pus- tule, and by the other symptoms which usually attend the malady in its progress. Some were predisposed to stupor, while others were restless and wakeful. Active delirium was not infrequent. Instead, however, of advancing in the ordinary way, we noticed many variations. One of the most common of the irregular forms was the " crystalline," in which the eruption continued vesicular. Deviating at first but slightly from the usual appearance, this variety afterwards became more distinctly defined by the unsym- metric shape of the pock and by the absence of color in the con- tained fluid, which did not pass on to purulency but left behind an immature and imperfect crust. The assumption that the pus- tule is an invariable accompaniment of the disease might lead to an error in diagnosis. In several instances the eruptive inflamma- tion extended to the larnyx, trachea, and to the larger divisions of the bronchia, producing hoarseness and sometimes complete loss of voice. This was a dangerous form, threatening death by 3 suffocation. Other modifications were observed, which indicated the great malignancy of the poison, furthered, perhaps, by subtle endemic influences which weakened the power of resistance in the system. The effect was seen in the quick and complete prostra- tion of nervous energy, followed by an imperfect development of the eruption or even its subsequent retrocession. A still more striking proof of the potency of the poison is afforded by the fact that not less than eleven of the sufferers had previously had the disease. It is well known that the small-pox is more malignant in cold than in warm weather. It may be, too, that the frequent and heavy fogs of last winter, coupled with rapid changes of tempera- ture, favored the spread of the pestilence either by affording a surer medium for the diffusion of the germs, or by depressing the vital forces. The poison accumulates and becomes more search- ing and uncontrollable as the numbers stricken down in a neigh- borhood increase ; conditions capable of resisting successfully the less energetic contagion of sporadic cases succumb helplessly as the epidemic spreads. Prophylactic measures, proved by abun- dant experience to be effective ordinarily, now disappoint with painful frequency the hopes of the physician. This shows the supreme importance of isolating every case at the outset and crushing the pestilence in its incipiency. The fire which, if taken in time, a single foot could stamp out, may, if given brief head- way, sweep resistlessly through the forest or across the prairie. As a preventive, vaccination is of paramount importance. Where the system is once thoroughly pervaded by the vaccine virus, the writer believes the protection to be complete. As the small-pox itself does not afford absolute indemnity against the subsequent recurrence of the malady, neither can vaccination claim to be an infallible safeguard. Zymotic diseases generally occur but once in the same person, yet certain constitutions pre- sent exceptional susceptibilities to the influence of specific con- tagions, which may thus affect them several times in the course of life. Ordinarily, if vaccination is performed within four or five days after the exposure of the unprotected to the variolous con- tagion, it gains precedence of the small-pox and affords complete security. But such, as might be anticipated from what we have said, was not the case at South Windham, at least after the pesti- lence had gained such headway that the air had become loaded with the poison. 4 The treatment of the small-pox at every stage of its progress demands from the physician the exercise of ceaseless vigilance and sound discretion. Erroneous and dangerous inferences were formerly drawn from the circumstance that the appearance of the eruption usually brings relief. It was thought desirable to pro- duce copious pustulation, and for that purpose heat and stimulants were freely used. The exact opposite is the truth. The less the eruption, the better. The fewer the pocks, the less the peril. The patient should lie in a cool and darkened room, under few bed clothes, with the access of an abundance of fresh air so grad- uated in temperature as to produce a sensation of agreeable cool- ness. Ice water and other refrigerant drinks are as salutary as they are refreshing. Persons of robust constitution should be kept on a light diet, while the feeble and aged require judicious support. The bowels and secretions are to be regulated by gentle medication so far as deviations from the normal standard call for interference. Inflammation, stupor, wakefulness, neuralgic pain, cerebral congestion, vomiting, and other symptoms, are to be con- trolled by the appropriate remedies. It is fortunate that meas- ures which minister to the comfort of the sick are generally salutary. In the advanced stages another class of perils menace the suf- ferer. The strength exhausted by extensive suppuration and by pain, now needs to be reinforced by the judicious use of tonics and stimulants. The cooling treatment indispensable during the progress of the fever should give place to a regimen of moderate and agreeable warmth. The small-pox has a definite course to run and no remedy can cut it short. As its severity is, as a rule, measured by the amount of the eruption, the main indication in the earlier stage is to re- duce the eruption to a minimum. Throughout, the treatment should be conducted on general principles, the materia medica offering no remedies which exert a specific control over the dis- ease, and yet in few maladies does the treatment determine more frequently the issue of life or death.