A CASE OF EXTRAUTERINE PREGNANCY; EMBRYO DESTROYED BY A TWENTY-MILLIAMPERE CURRENT WITHOUT INTERRUPTIONS; Together with Remarks on the Best Manner of Using Electricity for this Purpose. BY A. H. BUCKMASTER, M.D., OF BROOKLYN. FROM THE MEDICAL NEWS, July 21, 1888. [Reprinted from The Medical News, July 21, 1888.] A CASE OF EXTRAUTERINE PREGNANCY; EMBRYO DESTROYED BY A 20 MIL- LIAMPERE CURRENT WITHOUT INTERRUPTIONS; Together with Remarks on the Best Manner of Using Electricity for this Purpose.1 By A. H. BUCKMASTER, M.D., OF BROOKLYN. On the 16th of February, 1888, Dr. A. J. C. Skene requested me to see Mrs. C., for the purpose of destroying an embryo that was developing outside of the uterus. The patient was an Englishwoman, twenty-nine years of age, and gave me the following history: She had been married four years; had one miscar- riage two years ago, and has a child three years of age. Her menstrual periods recur regularly, and have always been plentiful. She was troubled with dysmenorrhoea previous to her marriage, but since then has been free from pain. Last October the patient changed her residence, and menstruated the latter part of that month. She did not menstruate the following month (November), 1 Read before the New York Academy of Medicine, Section on Obstetrics and Gynecology, May 24, 1888. 2 BUCKMASTER, and thought she was pregnant. She had never passed over a period except when enceinte, and was much troubled with nausea and bladder irritation, symptoms she had experienced previously only when bearing child. On the 26th of December (the day on which the Christmas feast was held), while assisting in the preparation of the dinner, she had what she described as a " very queer turn." She said: "I never felt better in my life than I had that morning." A short time before dinner she became nauseated and went to the bath-room to vomit. She suddenly felt a violent pain in the " pit of the stomach," heard a ringing noise in the ears and fainted. She lay on the floor groaning and did not have strength enough to call loudly for assistance. She was found in this condition by her husband and removed to her bed. It is said that her face was very pale, and she fainted at each attempt to sit up. She was very thirsty, and "thought the doctor cruel" in that he did not permit her to drink all the water she desired. Dr. Francis W. Bowron, the family physician, was sent for, and from him I obtained the following history: " On December 26th I was summoned in great haste to Mrs. C., who was reported to be dying. I found her in a condition of collapse, pulseless at the wrist, the lips bloodless and the face pale and ghastly in expression. The heart was irregular and intermittent, and there was great pain in the abdo- men. She was treated as a case of internal hemor- rhage and in the evening rallied. The next day the symptoms of pain and shock recurred, and on the 28th there was again an attack, but of much less EXTRAUTERINE PREGNANCY. 3 severity than before. On the 12th of January there was a recurrence of these fainting spells, also on the 13th and 14th of January. Dr. Skene saw the pa- tient, who had been rapidly increasing in size, on the 14th of February, and made the diagnosis of extrauterine pregnancy. He recommended that Dr. Buckmaster be called in to use the electric current for the destruction of the foetus. The increase in size of the patient's abdomen was arrested after the first treatment by Dr. Buckmaster. The patient is now her natural size and in fair health." The following notes were obtained from Dr. Skene: " I saw Mrs. C., in consultation with Dr. Bowron, on the 14th of February. I found the lower part of the abdomen enlarged. The right iliac region was the most prominent, and there was slight tenderness on touch. Dulness on percussion from the right ilium across the lower part of the abdomen and up- ward to somewhat more than half the distance to the umbilicus. On the left side the dulness did not extend upward more than two inches. An ill- defined mass, elastic to the touch, was distinctly traceable on the right side. Vaginal examination showed that the uterus was crowded forward toward the pubes, and that it was somewhat enlarged and softened. The sac of Douglas was occupied by an elastic mass, in which fluctuation could be detected, and which felt not unlike a small ovarian cyst, and seemed to be part of the tumor felt in the right iliac region, from which the uterus appeared free. " The diagnosis was between an ovarian cyst fixed on the right side and an extrauterine pregnancy. Taking the physical signs with the clinical symptoms 4 BUCKMASTER, a diagnosis of the latter condition was made. The general impression left on the mind of the examiner was that, without doubt, it was a case of extra- uterine pregnancy." I saw the case with Dr. Bowron on the 16th of February, and found the conditions as just described by Dr. Skene. The patient stated that she had pro- gressively increased in size during the past three weeks. After carefully considering the different methods for destroying the foetus, none of which seemed alto- gether satisfactory, I determined to use the galvanic current without interruptions, for reasons that will be stated later. The current1 was gradually increased by means of a rheostat until a strength of 20 milliamperes was reached-no attempt to go further than this was made, as the patient felt some pain. After main- taining the current for ten minutes it was gradually decreased. The patient experienced no shock. For the abdominal electrode was used a large plaque of clay with sixty-four square inches of contact; the vaginal electrode was of steel covered with wet ab- sorbent cotton. I w'as careful to press down on the abdominal electrode as much as the patient could bear, and also to raise the electrode in the vagina so that the current could be in as intimate relation to the foetus as possible. I regard this as important, because the fluid about the foetus offers so much re- sistance to the passage of the current. At the end of the seance the patient declared herself much re- 1 A fifty cell chloride of silver battery, made by Mr. Barret, was used. EXTRAUTERINE PREGNANCY. 5 lieved from the pelvic pain that had greatly annoyed her. I attributed this relief to the sedative influence of the positive pole. I had used the positive pole in the vagina anticipating this result. Six days after the first treatment the patient was again seen and her physical condition found to be much improved. The appetite had returned and the abdominal circumference had markedly decreased. Both the patient and her friends were delighted with the result. The physical examination was very satisfactory. The cyst seemed to have lost much of its fluid contents. I felt quite sure that the child was dead, but as the thorough examination started up the old pelvic pain, I made another electrical application. The third, and, subsequently, three more applications were made for the relief of this pain, at intervals of about six days. None proved so efficacious as the first. At the third treatment the measurement around the abdomen had increased about an inch, and six days later was half an inch more, but after this, the circumference measurement steadily decreased. Toward the end of February and also at the end of March, the patient menstruated. The patient was seen three months after the first treatment and was in very good health. A hard mass can still be felt by making a vaginal examina- tion, and there is a slight tenderness about it. The questions which would naturally suggest them- selves with this and other cases of this kind are: ist. Was the diagnosis of extrauterine pregnancy warrantable ? We had the subjective symptoms of pregnancy already enumerated : nausea and irritable bladder, 6 BUCKMASTER, and these symptoms were of special significance be- cause they had existed with the previous pregnancy and at no other time. Coupled with the cessation of the menstruation, the diagnosis of pregnancy would be highly probable. The uterus, although somewhat enlarged, did not correspond in size or condition of the cervix with the pregnant uterus of this period. It was pushed forward, and the fundus could be felt above the pubes. In the sac of Douglas was a large fluctuating mass rapidly increasing in size. About the time the second period was due the patient suffered from cramp-like pains followed by signs of internal hemorrhage. From the foregoing facts the case is about as clear as possible, except that there is no definite statement as to the casting off of the decidua, but we know it is often impossible to utilize this sign. 2d. Was the child living when the electricity was first applied ? The rapid increase in size observed by the doctor and the patient during the latter part of January and during February, after the symptoms of a peritonitis had subsided, indicated, by exclusion, a living ovum. Conversely we supposed the death of the ovum from the fact that the tumor decreased in size immedi- ately after the treatment. It not only decreased in size but changed in character, losing its elastic feeling on account of the absorption of the fluid contents. It has been claimed recently that the placenta con- tinues to grow after the death of the foetus, but as we have seen no corroborative evidence, it is not worth consideration at present. EXTRAUTERINE PREGNANCY. 7 3d. Is the uninterrupted current the best means for destroying the foetus ? I shall say but little as to the advisability of the use of electricity. So many eminent Americans have advocated its employment, that it has justly become known as the American plan of treatment. Although an Italian, Bachetto, first used the current for the destruction of the foetus, he used it in con- nection with puncture, a procedure which indicates that he had no conception of the advantages of this potent agent. So, as Dr. Garrigues very justly re- marks, the honor of priority may be justly claimed by America. Dr. T. G. Thomas, whose experience has been very large, says, in his characteristically forcible manner, "It has these great advantages: if an error of diagnosis has been made, this remedy will do no harm; if the diagnosis be correct, expe- rience proves it to be sufficient in its effect; . . . and it requires no surgical skill in its use."1 Many cases will undoubtedly appear as the literature of the subject expands, in which, after cutting into the abdomen, it will be found impossible to complete the operation.2 Three methods are in use for the destruction of the ovum by electricity.3 In the first method we may mention the use of the primary or secondary current of the ordinary faradic machine. This 1 Trans. Amer. Gyn. Soc., vol. lx. 2 See autopsy by T. G. Thomas, Trans. Amer, Gyn. Soc., vol. viii. p. 167. 3 The use of the static form of electricity is not considered be- cause of the difficulties in the way of its application. 8 BUCKMASTER, method is the one that has been most commonly used. For the second method we use a galvanic current of from ten to sixty milliamperes with in- terruptions ; and in the third class we consider the use of the galvanic current of effective intensity without interruptions, and increased or diminished gradually.1 The first method depends for its effectiveness on the shocks produced by the rapid breaking of the current by the magnet. The current strength is in- significant, and is usually obtained from two cells. Landis2 applied the poles of a Flemming faradic bat- tery against the shoulder and opposite rump of a newborn rabbit, and then used the full force of the battery for five minutes, and yet the rabbit recov- ered. A newborn rabbit is killed by very slight violence, and it would appear from this and other experiments, which he made on minnowsand beetles, that embryonic life is not so easily destroyed by this agent as one might imagine. This idea will be confirmed in reading the very interesting history of a case of extrauterine preg- nancy by Dr. Ely Van De Walker.3 He used a powerful induction coil. He says : " The irritation from one induction coil was such that it could not be tolerated elsewhere about the body for a 1 At the meeting of the Section before which this paper was read the writer stated that he believed his case was the first one in which the current had been applied in the manner above mentioned. He finds, however, that in Dr. Janvrin's case, which antedates his, it was so applied at Dr. Rockwell's suggestion. 2 Landis: Amer. Joum. of the Med. Sciences, October, 1885. 3 Trans. Amer. Gynecolog. Assoc., vol. xii. p. 296. EXTRAUTERINE PREGNANCY. 9 momentShe had ten seances of half an hour duration each, on the same number of consecu- tive daysOn the pelvic mass there was no evidence that I had made any impression what- ever. Its size remained the same, and its resistance to the touch, or what I would prefer to term tension, was unchanged." He determined to prolong the treatment to an hour. "We did so for three successive days, using the full strength of the induction coil. On the third day we found evidence that the electricity was accomplishing its work." The danger of producing rupture of an already weakened tube has been pointed out, but some of the recent writers are disposed to belittle this risk because we have no deaths directly traceable to it as a cause. We have had as yet too few cases reported to draw any such deduction, and the dangers of a possible rupture offer td my mind a valid objection against the use of the faradic current. By the second method, in which a comparatively strong galvanic current is used, the advantages of the first method are rendered greater, and the dan- ger of rupture is also increased. This is so true that I doubt if the second method is justifiable with our present knowledge of the subject. t)r. A. J. McCosh, speaking of a case treated by this method some time ago, says: "The contraction of the legs and abdo- men was very energetic when the current was inter- rupted." 1 On February 15, 1887, at a meeting of the Ob- stetrical Society of New York, Dr. Paul F. Mund£ remarked that he had reported a case two years be- 1 Trans. Amer. Gynecolog. Assoc., vol. ix. p. 173. 10 BUCKMASTER, fore in which one pole was introduced into the rectum, and twenty four cells were used with inter- rupted shocks; the foetus was killed, but the patient received such a severe shock that she was collapsed, and was restored only after receiving repeated hypo- dermatics of brandy, ether, etc.1 We use the third method precisely as we use the galvanic current for the destruction of a fibroid tumor. That a current of twenty milliamperes strength has a profound effect upon the cellular structure is shown by experiments that I made upon the heart of a living dog,2 in which it was observed that the striae of the heart's muscle became granular and indistinct. I speak of this to indicate with what a potent agent we are dealing, and also it gives us a reason to under- stand how the current is effective. In the case reported by the writer, twenty milliam- peres of current apparently caused the death of the embryo ; but if this amount of current should prove for any reason inefficient, or if instant results are desired, it may be increased upto 100 or 150 milliam- peres if necessary, when there could be no doubt of the result being attained. Sixty to eighty milliam- peres are often borne without discomfort by the patient without an anaesthetic. The fluid about the embryo offers so much resistance that the electrodes should be brought as near the child as possible, and to accomplish this the abdominal electrode should 1 Amer. Journ. of Obstet., April, 1887. 2 Prize Essay read before the Alumni Association of the Long Island Hospital Medical College, 1888. EXTRAUTERINE PREGNANCY. 11 be pressed down and the vaginal electrode raised under the mass. The writer has not considered the question of the use of electricity in connection with puncture of the sac, because he believes, from the experience of reported cases, that this procedure is more dangerous than laparotomy. To recapitulate in regard to the three methods of using electricity for the destruction of the foetus : 1. The faradic current is not certain in its action and not without danger. It must be used a number of times and for prolonged seances. 2. The interrupted galvanic current is more effec- tive than the faradic and by far the most dangerous of the three. It should never be used, because the other methods will accomplish all that is claimed for it, and it is in itself exceedingly dangerous. 3. The uninterrupted galvanic current will accom- plish at once the death of the foetus; it will relieve the intense pelvic pain by the sedative influence of the positive pole placed in the vagina; it is without danger. In the application of this method, all that is neces- sary is any electric battery containing enough cells, connecting cords, a rheostat and a vaginal and an abdominal electrode. The battery used by the writer was the fifty cell chloride of silver battery made by Mr. John A. Barrett. It weighs but eleven pounds and is 11x7x6 inches, so that it can be easily transported. Mr. Barrett has also invented a dry rheostat which can be carried in the pocket and which will prove very 12 BUCKMASTER. satisfactory if the current strength desired is not greater than seventy-five milliamperes. The abdominal electrode consists of two parts, a plate of copper and under it a pad of ordinary cotton batting, two inches thick when dry. The latter should be applied so wet that the water drips from it. The copper plate may be procured from a plumber at the cost of a few cents, and cut with tin- ners' shears to the shape desired. A hole should be punched through it, and then by means of a piece of copper wire it can be fastened to the connecting cord. For the vaginal electrode almost any of those in the market, covered with a layer of wet cotton, will answer the purpose, and if they are large enough there need be no fear of cauterizing the vagina. The following rules for the application of the electricity may be followed with advantage: ist. Use the positive pole for the vaginal elec- trode. 2d. The electrodes being in place and the con- nections secure, permit the current to increase in strength gradually, by means of the rheostat, until the patient complains of pain. 3d. Press up the vaginal electrode and downward on the abdominal electrode, as much as the patient can bear. 4th. If the immediate destruction of the foetus is imperative and the patient cannot bear more than twenty milliamperes, use an anaesthetic and pass a 100 milliampere current. 5th. Decrease the current gradually at the expira- tion of fifteen minutes. the Medical news. A N ational W eeklyMedical Periodical, containing 28-32 Doub le- Columed Quarto Pages of Reading Matter in Each Issue. $5.00 per annum, post-paid Uniting in itself the best characteristics of the magazine and the news- paper, The Medical News renders a service of exceptional value to the profession. 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