[Reprint from Journal of Materia Medica.} The Early Removal of Tubercular Foci of the Bone. BY B. MERRILL RICKETTS, M. D. Read before Mitchell District Medical Association. Baden Springs,^Ind., July 13, 1893 It is not my intention to address you at any very great length, or present to you a subject upon which no thought has been given by the surgeons in general. My in- tention is to present some thought and evi- dence that may lead us to make an earlier diagnosis and to adopt more prompt and radical measures in tuberculosis of the bone than are generally adopted. Tuberculosis is one of the greatest enemies which the human body encounters. It is surely the greatest destroyer of bone anatomy. When once the frame, or any part thereof becomes diseased, the interest of all that is dependent upon it becomes jeopardized. What greater example can we have of this than in the de- struction of a part or all of one of the spinal 1 vertebne. Whatcanbemore deplorable than the various forms of spinal curvature, or.de- struction of the head of the femur, the meta tarsel or meta carpel bones? What feature is there more prominent than in the various causes of deafness, than that of tuberculosis? Syphilis has been accredited as the great de- stroyer of not only one, but of all kinds of tissue. It is a blessing compared to the ravages which tuberculosis produces, for in syphilis we have a remedy without much surgical interference. In tuberculosis our hands seem to have been tied, and the wheel of progress in its treatment made to stand still. There seems to be no constitutional treat- ment whatever ofthe least benefit in tubercu- lar disease of the bone. It is not because there has been no effort, for medical literature has been flooded with the various remedies suggested for its cure. It seems now that tuberculin has fallen short of our expecta- tions, failing in every particular, and giving no good results whatever. It seems to my mind, that the good to be obtained is through surgical interference only, and that it then depends upon early operative procedures. 2 Aseptic surgery has been the greatest boon to this class of work, and we-must necessarily rely to a great degree upon cleanliness. However, we see how difficult it is to secure primary union even in the extirpation of tubercular glands. Seeing how hard it is to overcome these obstacles and to secure primary union in operation upon the soft tissue, we must necessarily shrug our shoul- ders when we come to the extirpation of tubercular disease of the bones and joints. However, much I might be gratified to present this subject to you voluminously, I must confine myself to the early extirpation of the tubercular foci of the bone. I believe that surgeons in general are responsible for a large per cent, of the cripples as the result of tubercular disease. I am thoroughly satisfied that there has been too much delay, that we have expected nature to do what we ourselves should have done. How natural it is for us to shirk responsibility? My own plan has been to act promptly and radically where 1 have evidence of tubercular disease in either the shaft or epiphysis. Possibly I have at times been hasty, but I would rather 3 be accused of that than of procrastination, for surely the latter is the most dangerous. Even where there is a question as to the identity, it is best to give the patient the benefit of a doubt and operate promptly. In nearly all of the cases where the periosteum is thickened and tender, we have reason to suspect the presence of tuberculosis. Even in cases of trauma, tubercular bacilli seem to find their way and develop rapidly in the injured tissue. When once they are im- planted, they are not long in manifesting themselves and giving evidence of their presence. It is in just such cases as these, especially of the long bones, that an ex- ploratory incision and early extirpation give such excellent results. It is a matter of course that one should hesitate to open a joint as promptly as he would a shaft, but unfortunately the shafts are not so frequently attacked as the epiphysis. It is a great question, and one which must be considered greatly from the light of experience, as to a time when a joint should be opened. How- ever, I am safe in saying that the disease should be removed earlier when it attacks 4 the epiphysis than when the shaft alone is involved. If the foci are.thoroughly removed let them be upon the surface or in the body of the epiphysis, then the destruction of bone is much less and its ability to repair itself much greater. Then too, when early extirpated the possibility of the other bones being involved is lessened. The disease when confined to one foci, is not so rapid in its progress as where several are to be found, although the single one may be as large as several of the smaller ones combined. Then too, the greatest number of tubercular foci are found in the epiphysis because of its spongy nature. There is not much likli- hood of the foci being multiple in the shafts, because they are more compact. I do not believe that there is one loci in a thousand that undergoes spontaneous re- covery, let it be in the shaft or epiphysis, much less is it likely to recover if found in the epiphysis. Even rest, which has been so long considered a cure for tubercular joints, is of little avail, giving, to my mind, no evidence whatever of the reparative pro- cess as the result. When once an area has 5 become attacked by the bacilli, there seems to be no limit to the destruction which it may produce. If they do not become mul- tiple, the one will, in the course of time, destroy all the adjacent tissues. Tubercu- losis of the epiphysis is what epithelioma is to the skin, and should be looked upon with as great consideration, and the treat- ment made as radical. The earlier an epithelioma is removed the greater the chances for permanent relief. Just so with a tuberculous area within the bone. The influence of the diseased area seems to be nothing more than that of a foreign body, except the disease is more rapid and pro- gressive. The opening of a joint free from any disease could result in nothing more than ankylosis, to a greater or less degree. A joint affected with tuberculosis, neces- sarily results in ankylosis to a greater or less degree. Now, is it not better in cases where there is every indication of tuber- cular deposit, to give the patient the benefit of a doubt in exploratory incisions, followed, if necessary, by the removal of tuberculous matter? Until recently it was almost a 6 crime to open the abdominal cavity. Now it has become quite a common occurence, even though doubt exists as to what is to be found in that cavity. Just so with tuberculosis of shafts, and especially joints. What can we expect from any other than radical treatment? The development of large ovarian tumors does not now occur, simply because the gynecologists have be- come so skilled in making early diagnosis that procrastination can no longer be attrib- uted to them. It is to be hoped that surgeons who are called upon to treat the various forms of tuberculosis, especially of joints, will not delay radical operative procedures until there is great destruction of bone, accompanied by the formation of fistula. This is deplorable, and I think is largely due to the surgeon himself. Perhaps he does not early recognize the disease, or it may be due to his inclination to procras- tinate, or his fear in assuming responsillity. It is as unscientific to allow the head of the femur to become destroyed from tubercu- losis as it is to allow an ovarian tumor to grow until it weighs 50 to 75 pounds. It is 7 one thing for the patient or other influences to be responsible for such a state of affairs, and it is another for the responsibility to rest upon the attending physician. Just how much of the adjacent bone should be removed with tubercular foci, is a question for the operator himself to decide. I have no doubt but that in the majority of hip joint cases, the disease has progressed to a greater degree than is generally supposed at the time it is presented for treatment. We must expect all degrees of progress in the destruction of bony tissue as long as the people are isolated and out of reach of sur- gical aid. Poverty and indifference are prominent factors in the delay of treating all classes of diseases. But this should not be of any influence in establishing laws. Let the rules be established, and the good results made known, and there can be no plausible reason why the application should not become general. The Trinidad No. 137 Broadway, July 13, 1893. 8