Vaginal Hysterectomy in America, with Report of Two Cases. BY A. PALMER DUDLEY, M. D., burgeon, st. Elizabeth's hospital. REPRINTED FROM 2Tt)e Neto York fCUDical .JJoucnal for July 9 and 16, 188H. Reprinted from the New York Medical Journal for July 9 and 16, 1887. VAGINAL HYSTERECTOMY IN AMERICA, WITH REPORT OF TWO CASES. By A. PALMER DUDLEY, M. D., SURGEON, ST. ELIZABETH'S HOSPITAL. In no branch of the surgical art has greater advancement been made during the past twenty years than in the field of gynaecology. America justly lays claim to her share in this progress. During the time mentioned, hystero-trachelorrhaphy has traversed the rugged path to success, and laparotomy, for various forms of disease, has struggled from infancy with its many enemies to maturity with its thousands of friends, and now occupies an enduring place in modern and future surgery. In the same manner vaginal hysterectomy sprang into existence as a surgical procedure for the relief of a disease most loathsome and dreaded. It is a procedure yet in its infancy, but is daily laying increasing claims upon the profession for recognition, and, although not having its origin in America (for Andreas, of Cruce, is supposed to have done it in 1560, and Langenbeck is known to have done it in 1813, followed by Santu in 1822, Blundell in 1828, and Recamier in 1829), it was not looked upon with favor, and remained dormant as a surgical wonder until April 12, 1878, when Czerny revived it and did the operation which, with few changes, is the accepted operation of to-day. In Europe, during the past ten years, much has been written upon this subject, with scarcely a passing reference to American work. Here even the operation has been looked upon as an unsurgical procedure, cried down by almost the entire profession, while in the small amount of space devoted to it in our medical literature, foreign quotations and praise make up the major portions of the articles, much to the discredit of our own profession. My object in this paper will be to show what the profession of this country has accomplished with this operation, to place upon record a series of cases with individual methods of operation and treatment, and statistics which can not fail to be of in- terest, and to give America a just title to original work in this, as well as the operations previously mentioned. * Read before the Alumni Association of the Woman's Hospital at its third meeting. 2 VAGINAL HYSTERECTOMY IN AMERICA. No. Name of sur- geon. b£) Description of case. Manner of operation. Date of op- eration. Result. When last seen. Remarks. I. Dr. Anderson, San Fran- cisco. 56 Carcinoma of cer- vix and body. Circular incision of vagi- nal vault with a gal- vano-cautery. October 26, 1881. Recovery, with a vesi- cal fistula. February, 1882; no return of the disease. I. Dr. W. H. Ba- ker, Boston. Not pub- lished. 54 Carcinoma of body of uterus. Anterior, then posterior, incision; uterus retro- verted; section lig'tures; wound dressed openly. March 24, 1885. Recovery. Disease returned in Octo- ber, 1885 ; died May 25, 1886. I. Dr. A. C. Ber- nays, St. Louis. 52 Epithelioma, in- volving both lips of the portio va- ginalis. Dec. 12, 1883. Recovery. November 24, 1886; in good health. Had peritonitis lasting only a short time. II. cc 41 Epithelioma of cer- vix and extend- ing into the body • • May 10, 1884. Recovery rapid. December, 1886; no re- turn. Uninterrupted recovery. III. IV. u 42 50 Epithelioma of cervix and body; organ much en- larged. Epithelioma of cer- vix, involving some of vaginal vault. March 26, 1885. June 5, 1885. Recovery rapid. Recovery rapid. November 1, 1886; no re- turn of the disease. July 4, 1886; examined and found no return of the disease. Had some peritonitis with suppuration; tubes and ovaries re- moved with the uterus V. 36 Epithelioma; the entire posterior lip of c'rvix gone; growth extended into the body. August 1, 1885. Recovery rapid. December 3, 1886 ; slight suspicious thickening in the cicatrix. Had secondary haemor- rhage requiring liga- tion of small artery on the fifth day. VI. a 34 Epithelioma of cer- vix, extending to the internal os. November 4, 1885. Recovery rapid. December 4, 1886 ; no re- turn. I. Dr. J.G.Blake, B'st'n. "Bos- ton Med. & Surg. Jour." 42 Carcinoma of the cervix. Circular incision; liga- ments ligated en masse; uterus removed without version. January 28, 1880. Death in 12 hours from shock. The parts were so vas- cular the loss of blood was great. VAGINAL HYSTERECTOMY IX AMERICA. 3 I. Dr. Wm. T. 451 Epithelioma of the Circular incision; uterus February Recovery In October, 1883, the dis- Vagina tamponed with Bull, New York, "New York Med. Journal." cervix uteri. anteverted; broad liga- ments tied in sections; open dressing. 19, 1883. rapid. ease reappeared, and she died in eighteen months. peat-bags. II. a 86 Epithelial growth upon the cervix; cauliflower. u August 16, 1884. Recovery. March, 1886. Death from carcinoma of the peri- tonaeum. Five days before the hysterectomy the cauliflower cervix was removed. III. ci 85 Epithelioma of the cervix, extending to internal os. Circular incision; uterus retroverted; broad liga- ments tied in sections. September 24, 1884. Recovery. September, 1886, she re- mained well. One suture placed across the vaginal wound. IV. u 52 Epithelioma of the cervix. Posterior and lateral in- cision ; uterus retro- verted ; open dressing. July 4, 1886. Recovery. Right broad ligament tied in sections ; left broad ligament cut with cautery. V.' a 43 Cauliflower of the cervix. Uterus pulled down with silver wire and cut away from rect'm and bladd'r. August 27, 1886. Death Au- gust 27, 1886. Two transfusions of saline fluid before death. I Hemorrhage in meso- rectum. I. Dr. • Burke, Connectic't. Not report- ed. 37 Sarcoma of cervix; cauliflower. Uterine arteries ligated; uterus drawn down; cul- de-sac opened; liga- ments tied en masse ; uterus severed & drawn down; vagina stretched. November 11, 1882. Recovery rapid. During the present month, and found in good con- dition. The cervix was amputa- ted six months pre- vious to the operation for hysterectomy. I. Dr. Cushing, San Francis- co. " Am. Jour, of the Med. Sci.," 1882. 47 Carcinoma of the cervix uteri. Sims's position; uterine ar- teries ligated; uterus separated from bladder; ovarian arteries tied; uterus retroverted; vag- inal wound left open. September 4, 1881. Recovery rapid. One year after operation. Disease returned in six months and caused death in one year. I. Dr. B. F. Daw- son, New York. "Am. Journal of Obstetrics." Diffuse sarcoma of themucousmem- brane of the uterus. Circular incision; uterus drawn down and not ante- or retroverted, ow- ing to presence of a fi- broid in the body. April 7, 1885. Death on 3d day from fever. The uterus contained two fibroids, one interstitial. Autopsy showed fatty degeneration of the kidneys. VAGINAL HYSTERECTOMY IN AMERICA. 4 No. Name of sur- geon. o5 Description of case. Manner of operation. Date of op- eration. Result. When last seen. Remarks. I. Dr. De Vecchi, San Francis- co. "West- ern Lancet" 1883. 53 Epithelioma of the cervix and va- gina. Incision by galvano-cau- tery wire; mass liga- tures ; uterus retro- verted. March 1, 1883. Rapid rec'v- ery; died 2 years and 3 months after. She was under observation till death; the disease showed evidence of re- turn in one year. The disease involved ab- dominal organs; pa- tient died in great agony. II. G 50 g G No date. Rapid re- covery. The disease returned in 6 months, and the pa- tient died before the 6th mo. had passed. I. Dr. A. Palmer Dudley, N'w York. 4 1 Epithelioma of the cervix and right vaginal wall. Anterior vaginal opening; uterus anteverted; liga- ments tied in sections; open dressing. December 20, 1883. Recovery rapid. One year after operation; no return of the dis- ease. Death from laparotomy for entero-vaginal fis- tula. II. I. Dr. A. Palmer Dudley, N'w York. Dr. E. C. Dud- ley, Chica- go. Not re- ported. 48 Epithelioma of the cervix and body. Carcinoma of the cervix and ex- tending into the body of uterus. Anterior vaginal opening; uterus anteverted; liga- ments tied in sections; open dressing. Czerny's method of opera- tion. December 28, 1886. May 23, 1882. Death in 39 hours from acute ne- phritis. Died in four hours from shock. Complete suppression of urine twelve hours before death. I. Dr. J. W. El- liot, Bos- ton. "Bost'n Med. & Sur. Jour.," July 22, 1885. 39 Epithelioma of the cervix uteri. High amputation; ante- rior cul-de-sac opened; uterus anteverted; vag- inal wound tamponed with iodoform gauze. May 12, 1885. Death on the Sth day from haem- orrhage. This patient had high amputation in Janua- ry, 1885; was again curetted in March; death caused by haem- orrhage from torn adhesions. I. Dr. P. F. Eve. " Am. Jour, of the Med. Sci.," 1850. 28 Encephaloid of ap- parently entire uterus and upper part of vagina. Forcibly drawn down and removed with a knife. April 16, 1850. Recovery rapid. Two months after opera- tion; growth found re- turning in the scar. Death July 22, 1850, three months and one week after the opera- tion. VAGINAL HYSTERECTOMY IN AMERICA. 5 I. Dr. C. Fenger, 40 Carcinoma of cer- Uterus anteverted; broad September Recovery inlThe disease returned in A fistula made in the Chicago. vix and lower ligaments tied in two 19, 1881. four weeks. the posterior wall of bladder at time of "Trans, of half of the body sections; vaginal wound Died in bladder in 1884. operation was closed the Am. of uterus. closed with silk. Mav, 1885. with silk; the latter Gynaec. So- ciety." was a nidus for stone passed six months later. I. Dr. M. Frank- lin, Phila- 40 Epithelioma of the cervix uteri. November Death on Autopsy gave no evi- 11, 1882. fifth day dence of peritonitis; delphia. from shock. only a few lymph b'nds about the intestines, at the seat of the operation. I. Dr. Goodell, 50 Epithelioma of the Anterior, then posterior November Died No- Death caused by septicae- Iodoform tampon used, Philadel- cervix uteri. incision; uterus retro- 13, 1883. vember 15, mi a. and vaginal wound phia. verted; ligaments tied in sections. 1883. left open. II. Cl 64 u l< March 3, Recovery. Died October 25, 1886, 1886. from vaginal haemor- rhage. Cervix amputated six I. Dr. R. J. Hall, 35 Epithelioma of the Operation made for haem- August, Recovery. Seen last November; she New York. Not report- ed. 50 cervix and ex- tending into the body of uterus. orrhage; Douglas's cul- de-sac opened; uterus retroverted; open dress- ing; ligaments tied in three sections. Lithotomy position; ante- 1886. October 24, Death same was then well. weeks before the op- eration ; the intes- tines prolapsed dur- ing the operation. This operation was very difficult, owing to pa- I. Dr. J. B. Hun- Carcinoma of cer- ter, New vix and body. rior incision, then poste- 1885. evening York. Not rior, and uterus ante- from shock. tient's fleshiness and published. verted; section ligature of ligaments. Curetted and stitched narrow vagina. I. Dr. E. J. Ill, 42 Cauliflower of cer- May 30, Recovery. April 11, 1886; she shows November 17, 1886, still in good general New Jersey. vix. wound up ; incision on 1885. evidence of return of "N.Y. Med. right side first; anterior the disease. health. Jour.," Feb. cul-de-sac opened and 13, 1886. uterus anteverted; then left side treated, 6 VAGINAL HYSTERECTOMY IN AMERICA. No. Name of sur- geon. bD Description of case. Manner of operation. Date of op- eration. Result. When last seen. Remarks. I. I. I. II. III. IV. V. VI. VII. Dr. J. Taber Johnson, Washingt'n < Dr.Fr'dLange, New York. " Report of Surgical So- ciety." Dr. L. C. Lane, San Fran- cisco. a u u ll Dr. L. C. Lane, San Fran- cisco. 14 27 60 r. Epithelioma of the cervix extending into the internal os. Carcinoma of the cervix extending into the body. Epithelioma of the cervix uteri. cc ll ll ll Epithelioma of the cervix uteri. cc Anterior, then posterior, cul-de-sac opened; uter- us retroverted; section ligatures; iodoform dressing. Martin's method; uterus retroverted; ligaments tied in sections. June, 1885. November 11, 1886. November '11, 1878. 1878. 1884. 1885. 1885. 1886. 1886. Death in 4 days from peritonitis. Recovery rapid. Recovery rapid. Recovery rapid. Recovery rapid. Died in 48 hours from septicaemia. Died 1 week later from peritonitis. Recovery. Died two days after- ward. Four months before the operation the diseas'd cervix was curetted and cauterized. Autopsy showed no re- turn of the disease in the pelvis, but the mesenteric glands contained cancerous deposits. Death from pelvic ab- scess, which burst in- ternally. There was a speedy re- turn of the disease. The autopsy revealed retro-peritoneal haem- orrhage of some standing. February 5, 1887; per- fectly well. One year after, when she had ascites, and died soon afterward. Two months after opera- tion. Still living and doing well. Four months after opera- tion. VAGINAL HYSTERECTOMY IN AMERICA. 7 VIII. c< « 1886. Rapid re- covery. January 1, 1887. Well at the present time. IX. 44 December Rapid re- covery. Well at the present time. 4, 1886. I. Dr.W. II. May, Stockton, Carcinoma of the Circular incision; Doug- las's cu'-de-sac opened September, 1882. Death on Cause of death un- cervix uteri. the fifth known. Cal. first; uterus retrovert- ed; ligaments tied in three sections. day. I. Dr. Paul F. 43 Epithelioma of the Sims's position; anterior, October 10, Recovery. The disease returned in The ovaries and tubes Munde, N'w cervix uteri. then posterior incision 1883. nine months. were removed with York. "Tr. of vagina; uterus retro- the uterus. Am. Gynrec. verted; then ligaments Soc.," 1884. tied in three sections. II. 44 30 Sarcoma of the cer- 44 November Death in 40 vix uteri. 9, 1883. hours from internal bleeding. III. Dr. Paul F. 17 Epithelioma of the cervix ingrafted Lithotomy position; open'd first cul-de-sac; retro- January 30, 1885. Death in 30 Although this operation was more difficult Munde, N'w hours from York. "N'w upon lips of an verted uterus; ligaments shock. than the previous, he prefers the lithotomy York Obst. old lacerated tied in three sections. Soc.," 1884. cervix. position. I. Dr. Polk, New 27 Epithelioma of the Patient upon the back; July 14, Death on On the sixth day. Cause of death, septic York. cervix and body. circular incision of vag- 1884. the sixth peritonitis. inal vault; uterus retro- verted. day. II. u 31 Epithelioma of the Operation similar, but the January 6, Recovery Three months after opera- The disease returned in cervix and body, uterus anteverted and 1886. rapid. tion. three months. the uterus mov- able. removed. III. 44 57 44 Operation similar, but the uterus retroverted. March, Recovery rapid. Patient now well. 1886.' IV. u 66 44 Operation similar, but the May 27, 44 Seen last September, 1886, This was a very fleshy uterus anteverted. 1886. and disease found re- patient, with a nar- turning. row pelvis, 8 VAGINAL HYSTERECTOMY IN AMERICA. No. Name of sur- geon. St Description of case. Manner of operation. Date of op- eration. Result. When last seen. Remarks. V. u 55 Epithelioma of cer- vix and body, and the vaginal wall posteriorly. As in previous cases, but he was obliged to ante- vert the uterus. November, 1886. Death in 14 hours from shock. The autopsy showed im- plication of the glands of the broad liga- ments, evidence that the disease was not all removed at the time of the operation. VI. ii 45 Epithelioma of the cervix extending to the internal os. On the back ; anterior and posterior incisions with cautery; high amputa- tion of the cervix, then the body anteverted. December 18, 1886. Recovery rapid. Patient doing well at present. I. Dr. Reamy, Cincinnati. Epithelioma of the cervix and one half of the body of uterus. Uterus anteverted; after ligating uterine arteries and broad ligaments, stitched the peritonaeum to vaginal wall. August, 1886. Death in 48 hours from shock. Long ligatures were left, and vaginal wound left open. II. (4 47 Sarcoma of the body of the uter- us, not involving the cervix. cc November 8, 1886. Recovery in 4 weeks. The temperature never rose above 101°, or pulse above 108. I. Dr. W. E. Tay- lor, San Francisco. Not report- ed. IS Carcinoma of the cervix. Circular incision; posterior cul-de-sac opened; uter- us retroverted; section ligatures; vaginal wound sutured. August 14, 1881. Recovery rapid. The disease returned in April, 1882 ; death took place in August, 1882. II. u 51 Carcinoma of cer- vix and vaginal wall. Il August 19, 1881. Death Au- gust 20, 1881. In both these cases there was prolapse of the intestines into the vagina during the operation. I. Dr. Thomas, New York. Not pub- lished. 69 Epithelioma of the cervix extending into the body. Uterus retroverted thro'gh Douglas's cul-de-sac. October 5, 1882. Died on 7th day from septicaemia. The patient was much exhausted prior to the operation. VAGINAL HYSTERECTOMY IN AMERICA. 9 I. Dr. Van Ram- 30 Epithelioma of cer- Sims's position; amputa- July 16, Recovery. December 26, 1886 ; vagi-!Ovaries and tubes were I. dohr, New York. Dr. Von Hoff- 37 vix extending to internal os. Carcinoma of the tion of posterior lip of cervix; ligature of uter- ine arteries; uterus an- teverted; iod. tampon. Bladder separated from 1886. October 25, Recovery nal roof feels hard and suspicious. not removed. Post mortem showed IL man, San Francisco. Not pub- lished. 44 86 cervix existing four months. Carcinoma of body vagina first; then Doug- las's cul-de-sac opened, and uterus retroverted. 44 1883. May 1, rapid; died January 14, 1884. Recovery. Well at the present time. carcinoma of omen- tum and peritonaeum, but no return in the pelvis. III. 44 50 of uterus, exist- ing six months. Carcinoma of cer- Uterus retroverted; vagi- nal wound left open. 44 1886. Fall of Recovery. History of this and the IV. 44 53 vix. 44 44 1884. Fall of Recovery. following patient lost; they came from a dis- tance, went home well in four weeks, and have not been heard I. Dr. R. F.Weir, New York. " Trans. N. Y. Surgical Society." 44 40 Epithelioma of the Lithotomy position; blad- 1884. November Recovery. April 27, '85 ; the growth had commenced to re- turn. Patient only lived a few from since. II. 15 cervix uteri; cau- liflower. Epithelioma of cer- der separated first; uter- us anteverted; broad ligaments tied in three sections; vagina closed with catgut. 44 10, 1884. May 16, Death from Uterus much enlarged, I. Not pub- lished. Dr. Wile,Conn. 49 vix uteri. Carcinoma of the Bladder perforated by a retractor. Anterior incision; silk ligature carried over right broad ligament; then posterior vaginal wall opened, and left side treated. Divided uterus longitudin- 1885. November shock and loss of blood. Died No- hours. She had a sharp haemor- complicating the op- eration. During the operation I. "New Eng- land Med. Monthly," Feb. 15, 1883. Dr. C. M. Wil- 50 cervix uteri. Carcinoma of an 13, 1882. September, vember 16, from shock. Recovery. rhage from the right uterine artery, and it was ligated the second time. December 14, 1886; still in good health, with no evidence of return. the intestines pro- lapsed into the va- gina. The inversion had ex- son, Phila- d'lphia. Not published. inverted uterus. ally; tied arteries with catgut, and touched stump with cautery. 1886. isted for six years. 10 VAGINAL HYSTERECTOMY IN AMERICA. The credit for the first removal of the uterus per vaginam for malignant disease in this country, so far as I am able to learn, is due Professor Paul F. Eve, of Augusta, Ga., who, on April 16, 1850 ("Am. Jour, of the Med. Sciences," 1858), did vaginal hysterectomy for extensive malignant disease of the uterus and vagina-at that time diagnosticated as encephaloid. This operation was done in the presence of Dr. J. A. Eve, Dr. Longstreet, Dr. Montgomery, and Dr. Henry Campbell, and to the latter I am indebted for an accurate description of the case and operation. The patient, a negress, twenty-eight years old, had been married, but never impregnated. Her disease had existed for three years, attended by frequent haemorrhages from the vagina. She was placed under chloroform, in the lith- otomy position, and the growth seized with forceps, which repeatedly gave way, bringing with it large masses of necrosed tissue. Finally the growth was dragged down to the ostium vaginae, and, finding it impossible to remove the firm resisting body, it was carefully excised with a knife, from above down- ward, or in an antero-posterior manner. The left uterine artery, which bled quite profusely, was ligated with animal ligature. A solution of sulphate of zinc was applied to restrain further haemorrhage, which had been considerable. There was no protrusion of the bowel, or other severe symptom, following this operation. In the mass removed the uterus was readily recognized, with its Fallopian tubes and round ligaments. The patient returned to her home on the seventeenth day, and on June 15th, two months after the operation, rode eleven miles to see the doctor, who found the disease returning in the vaginal wall. She died from haemorrhage three months and one week after the operation. Such is a brief history of the first case of vaginal hysterectomy in the United States for malignant disease. But this, it seems, was not the first time the uterus was removed per vaginam successfully, although not for malignant disease, for I find that as early as September, 1834, Dr. John M. Esselman, of Nashville, Tenn., successfully removed the inverted uterus by means of the ligature, and his patient made a good recovery. He again did the operation successfully in August, 1843, for inverted uterus con- taining a fibroid. Others followed his example with success. From 1850 to 1878, a period of twenty-eight years, I am unable to find recorded a single case of complete removal of a cancerous uterus per vaginam. During that time in this country the fashionable method of operating seems to have been by abdominal section, and numerous cases are tabulated of removal of the uterus, or the corporeal portion of it, for malignant dis- ease or fibroid. As early as June 25, 1853, Dr. Walter Burnham, of Lowell, Mass., operated by this method, followed by Dr. Gilman Kimball, of the same city, in August of the same year. At the end of the period mentioned, on January 30, 1878, Freund's operation, with the history of which you are all familiar, was given to the profession. Numerous cases of it are recorded, but death followed so closely in its wake that I hasten to dismiss it from my subject; and, as it is the purpose of this paper to speak of vaginal hysterectomy for malignant disease only, I will simply give a passing notice to the removal of the uterus by other methods. VAGINAL HYSTERECTOMY IN AMERICA. 11 On October 17, 1876, Dr. Emil Noeggerath, of this city, reported a case before the New York Obstetrical Society (see page 150, " Trans.," '76 and '78), entitled "A New Operation for the Removal of the Uterus with its Peritoneal Envelope through the Vagina for Carcinoma," which he stated was the first operation of the kind. Undoubtedly it was, and has remained so ever since, for the operation was never finished. A word of explanation for this remark is necessary and just: The operation was undertaken per vaginam. The anterior and posterior vaginal connections were severed with the galvanic knife, the openings thus made were stretched with an Ellinger's dilator, and the finger was passed into the pelvic cavity to examine the broad ligaments. They were found to be hard and infiltrated, rendering extraction by the vagina difficult. The abdominal cavity was therefore opened through the linea alba, Plan's wire constrictors were passed in and the broad ligaments and tubes constricted ; then the abdomi- nal incision was closed. (This procedure at once excludes this operation from my list of purely vaginal ones.) The patient died of septicaemia on the fourth day. An autopsy showed the uterus in situ, although nearly severed from its ligamentous attachments by the constricting wires. The operation will pass into history as an uncompleted procedure, and I must look in another direction for the next successful case of vaginal hysterectomy in the United States. This I find to be credited to Dr. L. C. Lane, of San Francisco, who, on the 11th day of November, 1878, did the operation for epithelioma of the cervix, and repeated it the same year. His method of operation I shall speak of farther on. I can find no report of its having been done again until January 28, 1880, when it was performed by Blake, of Boston, whose patient died in twelve hours from shock. The next to perform it was Cushing (September 4, 1881), of San Francisco, followed in a few days by Anderson and Taylor, of San Francisco, and Fenger, of Chicago, with suc- cessful results. Up to this time, you can see, the western part of our country took the lead. Then surgeons in the East resorted to the opera- tion, and during the year 1882 six operations were done by as many operators, the result being a loss of five of the patients. In 1883 eight patients were operated upon by seven different operators with a loss of two. In 1884 eight operations were done by six operators, the result being one death, so that from November, 1878, to the first of the year 1885, thirty operations had been done, resulting in death in ten. I have records of fourteen operations that were done during 1885, nearly half the number of all those done in the previous years I have men- tioned. Of that number, eight ended fatally, and, with the exception of Lane', Munde', and Weir', they were the operators' first and only cases. But do not hasten to condemn this operation on that account. One who has tried it knows the difficulties he has to surmount, and no one can appre- ciate them until he has done it himself; and when he has, almost his first thought will be, I can do it better the next time. VAGINAL HYSTERECTOMY IN AMERICA. 12 The record for 1886 seems to confirm this statement, for of the twenty- one cases for that year, of which I have a record, with the exception of three, whose cases were all successful, the operation was done by old opera- tors, and of the twenty-one, five resulted fatally. This is a material in- crease over the records of the previous years, and evidences either an improvement in manipulative skill, or more careful choice of cases selected for operation. Of the sixty-six cases I have collected which are shown in the table, twenty-three resulted fatally, while forty-three patients re- covered and remained well afterward for periods varying from three months to three years (see table). The variety of disease for which this operation has been resorted to most frequently in this country has been epithelioma of the cervix uteri. It is difficult to tabulate the exact number of each form of the dis- ease, for, while one operator in his report speaks of his case as carcinoma of the cervix, another describes it as cauliflower, and still another as epithelioma, without going into details sufficiently to be positive. Of the sixty-six cases I have collected, thirty-three are designated epithelioma involving the cervix and extending into the body to a more or less degree. Only four cases are diagnosticated as carcinoma of the body, three as sarcoma of the cervix, and only one as sarcoma of the body-evidence of a much more frequent occurrence of the epithelial form of the disease. The methods of operation practiced by the operators of this country differ but slightly in their essential points. In the cases reported, two thirds of the surgeons have preferred the lithotomy position for the patient, while the remaining third have employed the Sims position. The choice as to opening the anterior or posterior cul-de-sac first has been about equally divided, while in the large majority of the cases the uterus has been retroverted for the purpose of bringing it into the vagina, and the broad ligaments have been tied in sections. Open dressing of the wound is the accepted method, iodoform gauze being used as an application to the cut surfaces, applied in the form of a loose tampon, and allowed to remain for several days, unless contra-indicated by a rise of temperature. Such is the method practiced by Dr. Lane, of San Francisco, who stands at the head of the list of operators, in point of number, having done nine operations, with a loss of three patients, while Dr. Bernays, of St. Louis, although second in point of number, heads the list of successful operators, having done six operations without a death. Dr. Polk, of this city, favors the dorsal position, and, as his method differs so materially from that practiced by others, I desire to mention the essential steps taken in its performance. The patient on the back, he divides the vaginal mucous membrane into the cellular tissue on the sides first, preferably with the galvano-cautery, then through these openings he passes his modified aneurysm-needle, hooks down the uterine arteries and ligates them before cutting farther. The anterior and posterior vaginal wall are then treated in the same manner. When this has been done the VAGINAL HYSTERECTOMY IN AMERICA. 13 patient is ready for the second step in the operation, which is a supra- vaginal amputation of the cervix. He then has only loose cellular tissue and peritonaeum to deal with. Before opening the latter, the vagina is thoroughly cleansed with an antiseptic solution. This being done, the peritonaeum is opened, and the remaining portion of the body is anteverted or retroverted, as the case may indicate. The ovarian arteries are then ligated, including as much of the tubes and ovaries as possible. The space then remaining between the uterine and ovarian arteries is ligated en masse, and small bleeding points in Douglas's pouch are ligated separately. No portion of the wound is closed by suture and no drainage-tube is used, but the wound is packed with iodoform gauze. In view of the good results obtained and reported by Dr. Baker at a previous meeting of this society, the question might be raised as to why the doctor should open the peri- tonaeum and remove the remaining portion of the body after having done so thorough a supra-vaginal amputation without loss of much blood. Opinions concerning the operation differ but slightly among the opera- tors of the United States. It is the universal opinion that it is limited to certain forms of the disease-namely, carcinoma of the body and epi- thelioma of the cervix, neither of which shall have advanced sufficiently to have involved the peri-uterine structures, and that the organ shall be perfectly movable. Dr. Hunter and Dr. Bull, of this city, believe this operation the best that can be chosen for the class of cases I have men- tioned. My own experience has been limited, but peculiar features of interest have attended it, and I have taken pains to follow the cases closely to their termination, and will report their results in full. My first was- Vaginal Hysterectomy ; Recovery. Entero-vaginal Fistula Six Months La- ter; Laparotomy for its Relief.-Mrs. G., aged forty-six, married thirty years, and the mother of six children, the last two years old; two miscarriages since the birth of the last child, caused by taking rhubarb ; menstrual function always regular, but profuse, with some pain during the flow; menopause six months previous. Her general health was poor, and she was thin and ansemic. Her present illness had lasted nine months. It began with pain of a lancinating character in the back, lower part of the abdomen, and vulva, radiating into the thighs and legs. The pain was increased by standing or walking. Local exami- nation revealed epithelioma of the cervix uteri, extending into the cervical canal, and also involving the vaginal wall slightly on the right side. The uterus was perfectly movable, and she had not suffered from haemorrhage. The patient's condition called for removal of the diseased tissues without delay. Removal of the uterus per vaginam was proposed, and on December 20, 1883, the operation was performed in the following manner: The patient was given an anaesthetic composed of equal parts of methylene and ether, and placed upon the left side in Sims's position. A large Sims's speculum was introduced, and the bladder was emptied and held forward against the pubes by a Peaslee's sound. I then grasped the cervix with a volsella, and carried it backward toward the posterior vaginal wall, thereby tilting the body of the uterus forward, and putting the anterior vaginal wall upon the stretch. The forceps being held by an assistant, 14 VAGINAL HYSTERECTOMY IN AMERICA. the vaginal wall immediately in front of the cervix was caught up upon a tenac- ulum, and, keeping the cervix as a guide, a semicircular incision, about an inch and a half long, was made with a sharp knife, the cut being continued until the peritonaeum covering the utero-vesical fold could be felt, and this also was caught up and cut with 'blunt-pointed scissors. The finger could now be readily passed to the fundus of the uterus, and swept along each broad ligament. Still retaining my finger within the incision already made, I introduced by the side of it the long handle of a scalpel, and gradually enlarged the opening by a process of scratching until it extended in a half-circle around the cervix to each broad ligament. Then, firmly fixing one blade of a volsella in the fundus, I made gradual traction forward, at the same time pressing the cervix back in the vagina until the fundus appeared at the opening, and was grasped with a catch forceps. The difficulty now arose of drawing the fundus into the vagina, but, by steady traction and using my thumb and finger, I was able (so to speak) to put the cut surface back over the fundus, and bring the latter into the vagina with little difficulty. A thin, flat sponge was then secured by silk, and passed into the pelvic cavity to protect the intestines. The patient being on the left side, the left or lower broad ligament was first ligated, including the ovarian artery, and was divided down to the vaginal roof, the uterine artery of that side still remain- ing untied. The uterine surface of the cut was secured by clamp forceps. The right ligament was treated in the same manner, and was severed down to the neighborhood of the uterine artery. The uterus was now perfectly movable, and I was able to readily pass a curved needle through Douglas's cul-de-sac at each side of the cervix, and to ligate the uterine arteries. This accomplished, both broad ligaments were entirely severed, and the uterus was separated from its attachment to Douglas's cul-de-sac and removed. The vagina was then thoroughly cleansed with a solution of bichloride of mercury, 1 to 3,000, and the cut surfaces were inspected to be sure that all diseased tissue had been re- moved. Several small points of indurated tissue were found. These were removed, including some of the apparently healthy tissue, until the whole cir- cumference of the cut surface felt soft to the touch. This started afresh the haemorrhage from the small vessels of the vaginal walls. These I did not at- tempt to ligate, as it is quite difficult to do properly, and takes much valuable time. The bleeding points were caught by small torsion forceps, which were allowed to remain until the next morning. The sponge was next removed from the pelvic cavity, and the latter was thoroughly cleansed with a solution of bichloride and sponged dry. The intestines could be seen lying high in the cavity, away from the pelvic roof. Another sponge was then introduced into the vagina and placed in apposition to the cut surface, and the patient was put to bed. The time of operation was one hour and forty minutes. The sponge was removed on the same evening, and the forceps the next morning. No haemorrhage followed. The patient's recovery was facilitated by sufficient mor- phine to relieve pain, together -with perfect cleanliness. The urine was drawn every six hours, and the vagina washed out with a solution of bichloride, 1 to 3,000. The bowels were first moved by enemata on the sixth day, and each day after that either by oil or enema. The daily temperature ranged from 100° to 102° F., and the pulse from 100 to 110. The ligatures were removed on the thirteenth day. Twenty days after the operation the patient sat up several hours. Twenty-six days after the operation, examination showed union per- fect, and she was discharged well. VAGINAL HYSTERECTOMY IN AMERICA. 15 T am well aware that vaginal hysterectomy for cancer is an operation not yet accepted by a majority of the profession as a justifiable procedure, and it is only by tracing such cases to their final termination that their histories become of any value in enabling us to draw just conclusions con- cerning such operations. This I have endeavored to do in the present case, and for a concise record of the patient's condition from the time she left the hospital until her death I am indebted to Dr. II. W. Smith, of Placer- ville, California, who kindly furnished me with the following history: The operation was performed in December, 1883, and she remained in good health until the following June, when, while making beds one day, she felt something suddenly give way in the lower part of the abdomen, and immediately began to have pain. She was then under the care of another physician. On July 28th she was seen by Dr. Smith in consultation, at which time she had stercoraceous vomiting, and all the symptoms of complete obstruction of the bowel. Examination per raginam revealed a hardened mass in the pelvis in about the position that the body of the uterus should have occupied. The doc- tor does not state the method of treatment adopted at that time. He did not see her again until the following November. During the interval the intestine had sloughed, and a fistulous opening into the vagina had formed so that the contents of the bowels passed entirely through this opening, which readily ad- mitted the passage of a large sound into the intestine. Very little cicatricial tissue surrounded the fistula. In November she placed herself under Dr. Smith's care, and desired an operation for closure of the fistula. At that time her gen- eral health was much improved, but she was mentally depressed, owing to her failure to secure permanent relief. At that time Dr. Smith scraped away some of the raw edges of the fistula, and, after submitting it to microscopical exami- nation, declared it to be non-malignant; but, finding some hard lumps in the region of the ascending colon, he thought that possibly the growth had re- turned higher up in the pelvis, and that the lumps felt might be infiltrated glands. But, after one month's observation, with repeated examinations, and finding no change in her condition, he consented to operate for closure of the fistula. December 13, 1884, she was again placed under an anaesthetic, and, assisted by Dr. Cook and Dr. Stone, he made an incision through the linea alba five inches and a half long. The abdominal contents were examined, com- mencing at the stomach and following the intestine down to its obstruction, which was found to be eight inches from the ileo-caecal valve. The ileum was twisted upon itself in a half-figure-of-eight manner, and bound down in Douglas's cul-de-sac by bands of plastic lymph, the remains of a former peritoni- tis. The portion of the ileum from the stricture to the colon had atrophied, and was no larger than a lead-pencil. The vermiform appendix was attached to the right broad ligament by plastic bands. After thoroughly examining the pelvis by conjoined manipulation, the doctor states positively that there was no return of the cancer present, and that the lumps felt were faecal concretions in the ascending colon. The intestines were normal except the atrophied portion, through which nothing had passed for six months. The spleen, kidneys, and liver were normal. After this thorough examination of the abdominal organs, the intestines were drawn up, and, after squeezing the faecal concretions from the caecum, the ileum was united to the ascending colon, just above the ileo-caecal valve, by the Lembert stitch, the KJ GINAL HYSTERECTOMY IN AMERICA- 16 serous surfaces being carefully brought together and the muscular coats being included in the stitches. Fine silk was used for sewing the gut together. After all the oozing had stopped, he closed the abdominal incision with silver-wire sutures, applied antiseptic dressings, and put the patient to bed. She reacted well after the operation, and in six hours flatus escaped from the rectum by passing a catheter, and for three days her condition was very favorable. Dur- ing the third night she had a natural passage from the bowels, the first in six months. Her temperature ranged from normal to 101 *5°, and her pulse from 112 to 128. There was no tympanites until the initiatory chill of peritoni- tis, from which she died on the morning of the fifth day, one year after the first operation. There are several interesting features in this case, which may be summed up as follows: 1. The advance which the disease had made before the operation was resorted to. The cervix was so much involved that it broke down when grasped by the forceps, and the right wall of the vagina also was somewhat affected. Still, at the expiration of one year, no return had manifested itself. (In an article entitled "The Limitation of Vaginal Hysterectomy," read before the American Gynaecological Society in 1884, by Dr. Paul F. Munde, he gives statistics of eighty-two operations, in thirty-two of which, or 39'2 per cent., the patients remained free from recurrence two years after the operation.) 2. The manner of operation. From what I can gather from the litera- ture of the subject (especially from the German), the usual position for operation is upon the back. Both anterior and posterior vaginal con- nections are severed, and the uterus is retroverted and brought into the vagina. It seems to me that the lateral (Sims's) presents many advantages over the dorsal or lithotomy position. In the former, fewer assistants and instruments are required to keep the parts in view, and the haemorrhage can be much better controlled, while the blood, escaping from the most dependent portion of the vagina, does not obstruct the view of the parts. Dr. Munde, in summing up the report of his cases, stated that in the future he should operate with his patient in the gluteo-dorsal position in prefer- ence to the Sims, his main reason being the difficulty of doing the opera- tion in case of narrow vagina. I can not see the advantage of the dorsal position, with the numerous retractors, even under such circumstances, for the narrow or contracted condition of the vagina can be largely overcome by thoroughly packing it with antiseptic cotton for a few days before the operation. 3. With the patient in the dorsal position, one of the most trouble- some features of the operation is to keep the intestines and bladder out of danger. In Sims's position both bladder and intestines are carried out of the way by force of gravity, and thus are Jess liable to be wounded. Again, by anteverting the uterus and drawing it down, while the posterior vaginal connection still remains intact, there is less liability of necrosed VAGINAL HYSTERECTOMY IN AMERICA. 17 tissue and poisonous fluids coining into contact with the intestines or pelvic peritonaeum, while the danger of concealed haemorrhage from bleeding vessels behind the Sims speculum (as happened in Dr. Mundb's case) is avoided; and certainly, after the uterus has been removed, the operator is better able to detect any portions of diseased tissue which may not have been included in the first incisions. These advantages of the side position tend to shorten considerably the actual time required to perform this operation, which is an item worth con- sidering. In my own case, although the woman had borne children, the vagina was not voluminous; still, the operation was completed without haste in one hour and forty minutes. 4. As to the best method of leaving the wound after operation. In this case I did not close any part of the wound with sutures, but left it to heal by granulation (and how far may this method have been the cause of the inflammatory adhesions which resulted in obstruction of the bowel and production of the fistula?), which is a rare occurrence after such an operation. Martin, in his last work, reports sixty operations for various forms of disease (carcinoma, sarcoma, epithelioma, and adenoma), in one of which an entero-vaginal fistula resulted, but in that case the cancer had involved the tissues around the uterus. His method of treating the wound is by closely uniting the peritonaeum and the vagina with interrupted sutures, applied with a sharply curved needle, the application of the sutures follow- ing closely upon each incision so as to avoid haemorrhage. They are passed through the vaginal wall and peritonaeum, returning on the same side so as to ligate all bleeding vessels, and at the same time fasten the perito- naeum around the circumference of the wound. The angles of the wound are then brought together with interrupted sutures. He concludes that a drainage-tube is necessary for a good result, and uses the soft rubber tubing. At stated intervals he cleanses the vagina, but does not inject water into the peritoneal cavity. The cut surfaces heal by granulation, and he afterward removes the peritoneal-retaining sutures carefully. In my case, as before stated, the wound was left to heal by granulation at the same time that free drainage was secured, and it healed perfectly in twenty days. The surgeons who have done vaginal hysterectomy have each his own peculiar way of treating the wTound after operation. While one stitches the wound closely around a drainage-tube, another is content to leave the wound to heal by granulation. But, as statistics show a decrease of mortality in proportion to the increase of our knowledge of antiseptic surgery in this operation as well as in others, the main feature of the after- treatment proves itself to be antisepsis, and for statistical evidence of this fact the reader is referred to a valuable paper by Dr. Sarah Post in the "American Journal of the Medical Sciences" for January of the past year. 5. This case is also of interest because it demonstrates how the intes- tines may be treated, in accidents to the latter, during or following such VAGINAL HYSTERECTOMY IN AMERICA. 18 operations or abdominal section for any purpose, even after a lapse of six months, without a proper movement. Since writing the preceding portion of this paper I have done the operation a second time, and, although not with such good success (it having terminated fatally), I desire to place a short report of it before you, in order to call your attention to some features of the case which to me have been most instructive. The patient was Mrs. Marie B., German, aged forty-eight years, married twenty years, the mother of ten children ; no miscarriages ; widow eight years With her first four children she had a physician ; the last six a midwife was in attendance. She ceased to menstruate at the age of forty-five, and remained well for nearly two years. Then she commenced to have pain through the back and pelvis, which continued until the time I saw her. For the last five months it had been severe, and accompanied with frequent haemorrhages per raginam. She first came to my clinic at the Northeastern Dispensary, December 20, 1886, when I made a diagnosis of malignant disease of the uterus, involving the cervix and extending into the body. I sent her to the Post-graduate school, where Professor Bache Emmet confirmed my diagnosis. She was admitted into the hospital on the 26th, and on the morning of the 28th of December the operation was done. During the two days that she bad been in the hospital the vagina had been packed as closely as she could bear with an iodized glycerin tampon. This served to prevent haemorrhage, remove the bad odor, and dilate the vagina to a considerable extent. The operation was done in the same manner as described in the previous case, excepting that after opening the anterior cul-de-sac I took the precaution to ligate each uterine artery before attempting to autevert the uterus. My trouble then commenced, for as I passed my finger over the fundus uteri I discovered that it contained a small fibroid in each horn, which widened the surface to such a degree as to make it impossible to bring the body of the uterus into the vagina. I anteverted it and brought the right horn, containing the largest fibroid, into the vagina, transfixed and ligated beneath the fibroid, and cut the latter away. I then allowed the uterus to fall back into the pelvis, turned it upon itself, and brought the left horn down, and soon succeeded in bringing the body through the incision into the vagina, but in my efforts to do this I lacerated the tissue considerably by making too much traction with the forceps. This promoted considerable bleeding from the left ovarian artery, which 1 readily controlled by casting the elastic ligature around the body close to the vaginal junction. Finding I had perfect control of all haemorrhage, which facilitated my work, I again severed the body close to the ligature. Up to this point the operation had been very difficult, and much time had been consumed owing to the fact that the vagina was narrow, making work exceed- ingly difficult; and this difficulty was further complicated by a whip-cord-like band of peritonaeum, which extended from the lower and posterior surface of the right broad ligament up the side of the pelvis to the true pelvic brim. This hand prevented my being able to draw the uterus down more than an inch, and obliged me to do the entire operation with it high in the pelvis. Having removed the major portion of the body, I transfixed and again ligated each broad ligament, slipped my elastic ligature, and cleared the remaining portion VAGINAL HYSTERECTOMY IN AMERICA. 19 of the uterus from the vagina. The small sponge, placed in the pelvis after anteverting the uterus, had prevented any blood entering among the intestines. The vagina was thoroughly cleansed, the sponge carefully withdrawn, and the wound filled with iodoform gauze. The patient went to bed with a weak pulse, but responded readily to stimulants and reacted rapidly, so that by 8.30 p. m. the pulse was good at 90, and the temperature 99'6°. She was given hot water to drink, with brandy as a stimulant, and passed a very comfortable night. The urine was drawn every four hours, about two ounces being obtained each time. At 11 a. m. the next day, the pulse and temperature having gone up rapidly since morning, I feared haemorrhage into the pelvis and removed the tampon, but found the latter sweet and no evidence of bleeding. I then passed the catheter and got no urine. Wondering what the cause could be, I was informed by the house surgeon that he got but very little from the last passage of the cathe- ter. Our efforts were then directed toward reducing the temperature and relieving the kidneys. The former I succeeded in with hypodermic injections of hydrochloride of quinine and urea and the application of the cold-water coil; but, although twenty minims of tr. digitalis and twenty grains of bromide and acetate of potassium were each given every hour, with hypodermic injec- tions of brandy as a stimulant, the kidneys would not respond, and the pulse gradually weakened and ran higher until death took place thirty-eight hours after the operation. After much persuasion, permission for an autopsy was obtained, and Pro- fessor Porter, pathologist to the school, kindly furnishes me with the following excellent report: The necropsy, which was limited to the abdominal cavity, was made about twelve hours after death. The peritonaeum was carefully examined and found to be absolutely free from any inflammatory action. The pelvic cavity con- tained no blood or serum, and the stump of the operation was free from suppu- ration and in a reparative condition. The spleen was small and fissured, but otherwise normal. Kidneys.-Both glands were enlarged, weighing six ounces (170 grammes) each. They were soft and of a whitish-yellow color. Their capsules were non- adherent to the underlying renal tissue, the surface of which remained perfectly smooth after enucleation. The mucous membrane in both pelves presented a marked congestion and puffiness, which would indicate the existence of an acute pyelitis. The cut surface of the glands showed the cortex to be thickened, pale, granu- lar, and fatty, but the markings were straight. Upon microscopical examination, the epithelium of the uriniferous tubules was found to be in a state of granular and fatty metamorphosis, many of the tubules being occluded by the desquama- ting epithelium, hyaline, finely and coarsely granular and fatty casts. There was no inflammatory change and no active change in the intertubular tissue; but the appearances were those of a rapidly progressing acute parenchymatous meta- morphosis of the kidneys, which had existed for a day or two only. The few drops of urine obtained at the time of the necropsy gave every evidence of the existence of the above lesion. A small lipoma projected from the surface of one kidney. This form of renal lesion is of comparatively frequent occurrence in connection with severe surgical operations, and explains many of the so- 20 VAGINAL HYSTERECTOMY IN AMERICA. called septic symptoms without suppuration, the erroneously named septic symptoms being due to a uraemic toxaemia from non-elimination. The liver was the seat of a marked interlobular cirrhosis. There was a small lipoma in the omentum, near the splenic flexure of the colon, that had under- gone fibrous and cavernous metamorphosis. Sections made from the uterine neoplasm were found to be composed largely of fibrillated connective tissue and non-striated muscle fibers. In some places this mixed tissue contained rings of cylindrical epithelium, commonly described as the cauliflower growth, or cylindrical-celled epithelial carcinoma, while in other sections the perivascular or lymphatic spaces were dilated into alveolar cavities, and were packed full of irregular epithelial cells without intercellular substance, and without any definite order of arrangement, this appearance being that characteristic of a scirrhous carcinoma. For a full description of the pathology and development of this form of renal lesion the reader is referred to Dr. Porter's work, published by William Wood & Co. REASONS WHY Physicians should Subscribe -FOR- The NewYork Medical Journal, Edited by FRANK P. FOSTER, M. D., Published by D. APPLETON & CO., 1, 3, & 5 Bond St. 1. 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