INTERESTING CASES OCCURRING IN THE SURGICAL CLINIC OF PROFESSOR W. W. KEEN, M.D., LL.D., In the Jefferson Medical College Hospital, Philadelphia. REPORTED BY A. G. ELLIS, Medical Student. [Reprinted from International Clinics, Vol. IL, Ninth Series.] INTERESTING CASES OCCURRING IN THE SURGICAL CLINIC OF PROFESSOR W. W. KEEN, M.D., LL.D., In the Jefferson Medical College Hospital, Philadelphia. REPORTED BY A. G. ELLIS, Medical Student. SUBDURAL DRAINAGE OF THE LEFT VENTRICLE FOR HYDRO- CEPHALUS. Gentlemen,-We have here a child, four months of age, suffer- ing from acute hydrocephalus. The case was kindly referred to me by Professor E. E. Graham, and is of unusual interest, and an unusual operation will be done in an attempt to save its life. The child's head has enlarged very rapidly, the circumference increasing an inch in one week. Lumbar puncture w'as done, but without suc- cess. In a case of internal hydrocephalus such as this is, the fluid can sometimes be drawn from the ventricles into the spinal canal through the foramen of Magendie and evacuated by lumbar punc- ture. In the present case only two cubic centimetres could be ob- tained in this way, with the advantage of showing, however, that the fluid was sterile. The operation to be done is the ingenious one suggested by Cheyne, of London,-i.e., subdural drainage of the lateral ventricle. The ventricle is punctured, three or four strands of catgut are slipped in, and then, instead of bringing the ends out through the bone and scalp, they are simply pushed under the dura. By this means the fluid, it is hoped, will be drained into the subdural lymph- space and absorbed. The great advantage of this lies in the fact that there is no external wound to dress day after day, and therefore no danger of infection. I care not who the surgeon is or what his technique may be, if he dresses a wound in which drainage makes this necessary day after day, and it may be two or three times a day, it is only a question of time when infection will follow. By Cheyne's method the skull is shut up, and the wound in the brain must be aseptic. 2 A METHOD OF DRAINAGE AFTER SCHEDE'S OPERATION. After reflecting a flap of scalp, I make a small trephine opening a half-inch in diameter, and then I make a small opening in the dura. By using rather stiff catgut just taken out of alcohol, I can push the catgut through the thin cortex into the ventricle as soon as I have made the opening. A very little fluid flows out, nor do I wish a free escape at the time. If much fluid is taken out at once, convulsions follow, and death ensues on the spot or in a day or two. It is a question if this is not best in many such cases of unfortunates. The other ends of the catgut are now slipped under the dura and the wound is closed. The stitches in the scalp are put in very close, to prevent leakage, as it is desirable to have the wound close up as soon as possible. [Considerable leakage occurred during the first twenty-four hours. This was arrested by iodoform collodion. The child re- covered from the operation, though the temperature immediately afterwards and for fourteen days rose as high as 105° and 106° F. No assignable cause for this could be discovered. The fever then ceased, but the child was not improved by the operation. The head, which in the month preceding the operation had increased one and one-eighth inches in circumference, at first shrunk, then again en- larged even beyond its former size. The child was still living several weeks after operation, but without any improvement.] A METHOD OF DRAINAGE AFTER SCHEDE'S OPERATION. The next case to which I wish to call your attention is that of a man who was operated on last week. 1 bring him before you especially to show the method of drainage used since the operation. This man had an old empyema, with a fistulous opening, which had existed for two years and a half. The opening was just below the second rib, higher up than I have ever seen before. The direc- tion of the sinus and extent of the cavity could not be well de- termined by the probe. A T-shaped incision was made, the three flaps were drawn back, the opening into the thorax was found, and with bone-nippers I made an opening large enough to permit me to look in. Schede's operation as modified by myself was determined upon, and the second, third, and fourth ribs were removed, thus taking the whole chest wall, excepting the soft parts external to the ribs, but including the thickened plura, from the lower border of the first rib. The cavity was packed with iodoform gauze for three days. A METHOD OF DRAINAGE AFTER SCHEDE's OPERATION. 3 Of course it was already an infected wound, and, not wanting the pus to collect or remain in the cavity, I used the plan of drainage intro- duced by Cathcart, of Edinburgh, and slightly modified by myself. A large jar of water is placed on a stand by the bedside. Leading from it is a rubber tube on which is placed a clip. This clip is not allowed to shut off the water entirely, but is held open with a small bit of tubing or other object so as to permit the water to run very slowly. This tube terminates in a "Y." This "Y" need not be of Fig. 1. Keen's improved method of drainage by siphonage. glass: a good enough one can be made of tin, or even of two pieces of tubing united by end-to-side anastomosis. One of the upper tubes leading from the " Y" goes into the man's chest and is held in place by plaster, the other upper tube is connected with the bottle of water. The third or lower tube from the " Y" is fastened to the side of the bed in a loop so as to form a siphon. This, of course, must be lower than the one leading from the wound. There is also a piece of glass tubing inserted in the tube from the wound, so that the action of the apparatus can be observed. The tube forming the loop fills slowly 4 FOCAL EPILEPSY, WITH THREE FRACTURES OF THE SKULL. and then siphons over, thus making marked suction each time it empties. Only a slow trickle comes from the jar, so the suction is ex- pended on the fluid in the cavity, which is thus drained out every few minutes. [This man was desperately ill after the operation, but was rescued by hypodermocylsis. Unfortunately, this caused two sloughs as large as the hand on each thigh, but they finally healed. His highest temperature was 101.6° F. He is sitting up in bed occa- sionally now, in order to avoid bed-sores. In a day or two the stitches will be cut, to let the chest wall fall in. An immense cavity was left by the operation, as the flap of soft tissues over the chest was far too small to cover its sides and floor. It is slowly filling up by granulation. Meantime the patient's general condition is excellent, and he is up and about. The micro- scopical examination by Professor Coplin suggests probably a pleural endothelioma as the origin of the empyema.] A CASE OF FOCAL EPILEPSY, WITH THREE FRACTURES OF THE SKULL, ONE OF THE BASE AND TWO OF THE VAULT. This patient is a railroad brakeman from Florida, whose head was caught between a car and a piece of timber. He comes to us with three distinct lesions: First, there is a marked depressed frac- ture of the skull over the left temple, where an angular ridge is distinctly felt. Second, there is a small depression in the vault of the cranium over the right parietal bone, which was presumably a fracture. Third, at the time of the accident he had bleeding from the nose and also vomited blood, but had no bleeding from the ears. This would indicate a fracture of the base of the skull in the anterior fossa, and he has another lesion which confirms this diagnosis. The right optic nerve is atrophied and this eye is practically blind. This shows a lesion at the base of the brain in front of the optic chiasm. This is an irreparable loss for which nothing can be done. The fracture on the left temple is giving no trouble. But on Kovember 1 the man had an attack of epilepsy, and four or five days after that he had a second attack. These started in the left foot, which began to shake before the attack came on. It is rather surprising that the arm is not affected also, but the leg centre seems to be the only one injured. Here is a case in which the knowledge of the localization of function assists the surgeon most markedly. Twenty years ago I should probably have trephined at the fracture on the left temple, TREATMENT OF EXSTROPHY OF THE BLADDER. 5 as that is so much more depressed and seems to have been so much more severe. But the history of his attacks clearly point to the much less marked depression on the right side, which is over the lower border of the centre for the left leg. The patient's epilepsy may be caused by laceration of the brain without fracture, or by a depressed fracture or by a fracture of the inner table only. On account of this uncertainty, the operation will be largely exploratory, but when the skull is opened whatever is necessary will be done. I open the skull with a large gouge and hammer, as I shall not replace the bone and this is a quicker method than trephining. The dura is normal and the bone seems not to have been fractured, in spite of the depression. I will now apply a faradic current by a double electrode before opening the dura. I test the strength of the current first, and make it just strong enough to flex my index finger. Moving it over the centres of motion, we see the fingers of the left hand flexed and movement in the calf of the leg. There is no soft- ness of the dura and no reasonable probability of a cyst or clot being present. But I will make a small opening in the dura, in order to be able to look in and see if the brain is normal. I shall make an opening small enough to be closed with one stitch. The advantage of such a small opening is that we are able to see if a larger one ought to be made, without making a large circular inci- sion with perhaps no reason for it. I see that the brain looks per- fectly normal, so the wound will be closed. Hereafter the wound can be reopened and pieces of bone put in to fill the gap. You may wonder why nothing was done to the brain. It seems to me there could be no good in any operation on it. There is nothing to encourage interference with it. Even if an existing scar were cut out, the resulting one would probably be as bad, and in fact no scar is visible. [Nine days after the operation he left the hospital, entirely well from the operation. His subsequent history is unknown.] TREATMENT OF EXSTROPHY OF THE BLADDER; THE RECTUM A SUCCESSFUL RECEPTACLE FOR URINE AND THE MEN- STRUAL DISCHARGE FOR TWENTY-TWO YEARS AND SEVEN YEARS RESPECTIVELY IN TWO CASES. This little baby has the rather unusual condition of exstrophy of the bladder, a malformation caused by failure of development in the anterior wall of the bladder and abdomen. The urine constantly 6 TREATMENT OF EXSTROPHY OF THE BLADDER. exudes and excoriates the skin, making a very deplorable state of affairs. Treatment, as a rule, is unsatisfactory. Various forms of flap operations have been devised, the best probably being the one in which a piece from above is turned down with the skin side towards the bladder and then a flap from each side is placed over this by sliding it sidewise. But this makes no urethra, and there is no possibility of making one. In these cases it is necessary for the patient constantly to wear a urinal. This, of course, is excessively difficult to keep clean and sweet. I have found that the best means of keeping such a urinal free from smell is to put a teaspoonful of chloral into it every time it is emptied. This answers the purpose well enough to make it a point worth knowing. Recently another method of treating these cases has been devised by Fowler, and it is the method above all others in my estimation, though by no means free from danger. The operation consists first in opening the belly and finding the ureters. Then the rectum is opened and the ureters are implanted in its sides. This does ad- mirably, and the patient is kept thoroughly dry except for the mucus secreted by the mucous membrane of the posterior wall of the bladder. But this is only slight in amount and can easily be attended to. I have recommended this operation in the present case when the child is old enough, and have advised the parents to wait some time. The child is so small now that the operation would be very difficult. When it is ten or twelve years old, or even before if it grows fast, the operation can be done. The question naturally arises whether the urine will irritate the rectum, and if it will be retained under such circumstances. The rectum seems to answer such purpose very well. In confirmation of this, only last week I saw a patient with a most interesting history. She is a woman who during an attack of typhoid fever noticed that urine was escaping from the vagina. Soon after faeces also made their exit by this passage, the infection of the fever having caused gangrenous sloughs from both the recto-vaginal and vesico-vaginal septa. One of my colleagues and I did a number of operations to relieve this unfortunate woman, she being a social pariah on account of her condition. In all she had thirteen operations done. She was nearing the climacteric and was a widow. After the operation had been explained to her, she readily consented to have the vagina entirely closed. To obtain this result, at the last operation I excised FRACTURE OF NOSE. 7 the remnant of the urethra left and totally closed the vagina. That was in 1876, and she has been well and dry and clean ever since and able to work as a nurse. Both urine and fseces now pass through the rectum, and while she menstruated that discharge also took the same course. The urine has never irritated the rectum, and she has done well ever since the operation, with the exception of one occa- sion, when a small calculus formed in the vagina and acted as a ball valve. It was readily crushed through the anus and the recto-vaginal fistula by a simple curved pair of haemostatic forceps. She generally voids urine two or three times during the night. I have recently had another case in which for an incurable vesico- vaginal fistula Professor Parvin seven years ago totally closed the vagina after making a recto-vaginal fistula. No trouble has been experienced from the urine and menstrual discharge in the rectum, but there has been such contraction of the recto-vaginal fistula as to give her great annoyance. Dilatation has relieved her entirely. A NOSE DEFORMED BY FRACTURE GREATLY IMPROVED. Our next operative case is one in which an attempt will be made to restore the shape of a nose which has been deformed by a com- pound fracture. The patient is a girl who some time ago fell and sustained a compound fracture which has left a saddle-shaped nose. I have had a dentist make a cast of this nose, and then from that a model by which he made a plate to be inserted. The plate is a double one, with an air space between in order to make it light. The plate is made of silver and then gilded. Along the margins is a row of holes, which have been left with the hope that granulation tissue will grow up through these and, becoming fibrous, will hold the plate firmly in place. The first operation of this kind by myself was done four years ago, and the gold piece is yet in place and has given no trouble. A similar case in Australia, done some years be- fore my own, was doing perfectly well seven years after operation. Other supports have been used, such as celluloid, which does very well. Aluminum is too easily destroyed by the fluids of the tissues. If there was no scar a small opening at the side would be made and the plate slipped in, but as there is a scar here, an incision in it will make it no worse. An incision is made, and the tissues are loosened from the bone and cartilage with a dissector, being very careful to avoid infection by not invading the cavity of the nose. A 8 SARCOMA OF AN ECTOPIC TESTICLE. few cases have given trouble by irritation, but this has not occurred in the two cases mentioned. The external wound will be sewed with a fine needle and the finest silkworm gut. The stitches will be re- moved as soon as possible. In order to guard against the possible collecting of blood under the plate, I shall put in a double strand of silkw'orm gut for drainage, which will be removed to-morrow. A dressing covering both eyes as well as the wound will be applied, great care being taken not to use too much pressure, as a slough might easily form over the plate. [The patient made an excellent recovery by first intention. Some months later one corner of the plate, which was not pushed far enough from the wound, protruded and the plate was removed. A second attempt to insert the plate will be made in the autumn.] We owe this case to the courtesy of Professor Hearn. The patient is thirty years of age, was married five years ago, but has no children. Six years ago the left testicle descended into the inguinal canal. Soon after the right came down the same distance. In this position they are subject to pressure and violence and are apt to undergo sarcomatous degeneration. At the present time there is a hard mass in the right inguinal region where the right testicle lodged. It is ten centimetres long and half as wide. The skin over it is freely movable, but the tumor is tightly adherent to the pelvic brim. There is another tumor, at least twenty centimetres in length and six in width, extending from the left of the umbilicus, under the liver and colon, towards the right side and the xiphoid. It is dense and also fixed. We have, therefore, (1) a partially descended testicle in the left inguinal canal, (2) a sarcoma of the right partially descended testicle, and (3) a large sarcoma in the retro-peritoneal tissue of the abdomen, in all probability secondary to the one in the groin. Oper- ation is out of the question here. The man has come too late. An ectopic testicle should be placed in the scrotum by operation or, fail- ing in this, be removed. It is generally of no value sexually, and this man would seem to belong to this class. I have seen one man who had both testicles in the scrotum, normally developed genitals, and normal sexual desire and its normal gratification, and yet who had not a single spermatozoon in the spermatic fluid. In the last few years many operations for transposing an ectopic SARCOMA OF AN ECTOPIC TESTICLE. MYXO-SARCOMA OF THE TONSIL. 9 testicle into the scrotum have been done, especially in France. Some years ago I assisted Professor J. Chalmers Da Costa in operat- ing on such a case. He found that he could not bring the testicle down far enough, and therefore he dissected the cord loose from the posterior aspect of the testicle and simply turned the latter down into the scrotum, with an excellent result. MYXO-SARCOMA OF THE TONSIL. This case has been an interesting one and has presented several serious phases. The patient is a girl eighteen years of age, sent to us by Dr. J. D. McLean. She presented herself several months ago with a growth in the right tonsil. An operation was urged at that time, but this was declined by her parents. The tumor had increased in size until it nearly filled the entire oro-pharynx and very seriously interfered with her breathing when she returned early in October. The glands of the neck were involved and they were first removed. My intention was to extirpate both carotids, as suggested by Dawbarn, to prevent recurrence, if possible, by starving the growth. By at- tacking the glands first and laying bare the vessels, I should have instant control of them in case of serious haemorrhage when removing the tumor. While removing them dyspnoea became most alarming, and tracheotomy seemed imminent. To avoid this, if possible, about one-third of the tumor was cut off with a pair of scissors. One of the first steps in the operation on the neck had been to throw a loose ligature around the cartotid, so as to enable me instantly to control haemorrhage should it be alarming. This was not required, as the bleeding was moderate. The relief was immediate, and the haemor- rhage was easily controlled by iodoform gauze. The Trendelenburg posture was of the greatest assistance. In fact, without it operation on the immense growth would have been almost impossible. After removing the glands in the neck, the external carotid artery was dissected out, its branches were ligated, and about four and a half centimetres of the artery excised. The remainder of the tumor was then removed through the mouth, without splitting the cheek. When the patient had recovered, which she did nicely, Professor J. Chalmers Da Costa operated upon the glands and dissected out the external carotid artery on the opposite side. This operation proved a serious one. The glands were involved more than was suspected and were very adherent. So strong was the adherence that the jugular 10 LEONTIASIS OSSIUM. vein was torn in removing them, but was secured by double ligatures. Then the external carotid was looked for, but could not be found. A dissection was made far up the neck without result, and then the carotid artery was followed down as far as possible, when it was found that there was no division on that side and consequently no external carotid to excise. This is a rare condition and made the operation a puzzling one. [The patient recovered from the second operation. Unfor- tunately, two months after the operations there was a slight recur- rence on the postero-lateral wall of the right pharynx, for which another operation will soon be done.] RECURRENT CARCINOMA This woman had her breast removed by anothei surgeon a year or two ago, and now presents the following condition. The right arm is oedematous to such a degree that it is at least twice as large as the left. The glands above the clavicle are involved and can be easily felt. No enlarged glands are to be detected in the axilla, but there must be involvement of those near the vein, as is shown by the oedema of the arm. The sternum is tender to the touch. In the way of local treatment nothing can be done in this case. Only one operation is possible, and that is not very promising,-the removal of both ovaries. This treatment is in the experimental stage at present. Just what connection there is between these organs and the growth or hinderance of cancer is not known: whatever is said about it is only theory. It is thought that there is probably an ovarian secretion, which when poured into the system is favorable to the growth of cancer. The operation has been done several times. A very few of the patients have improved, but the majority go on to death. However, considering the comparative safety of abdominal operations, in a woman to whom the ovaries are no longer of func- tional value the procedure is worth trying. It is the only hope, and I shall suggest to this woman such an operation at an early date. [The operation was declined.] LEONTIASIS OSSIUM. The last case is that of a girl ten years of age. Six years ago the left eye became inflamed and gave considerable trouble. Shortly afterwards a swelling was noticed in the frontal region above that eye. This enlarged, the eyeball being pushed downward, and optic Fig. 2.-The ease of leontiasis ossium after the second operation. LEONTI ASIS OSSIUM. 11 neuritis was present. A tumor of the frontal lobe was thought pos- sible, although the absence of cerebral symptoms gave rise to un- certainty. There had been no mental symptoms, as is generally the case in frontal tumors. The child remained as bright as any one of her age would be. There was no epilepsy nor headache. A large flap of skin was turned up, but on trephining the skull was found to be enormously thickened. The bone was so soft that it was easily gnawed away with the bone-forceps, and could even be shaved off with a scalpel. The dura was exposed over a large area. An examination of the orbit showed no necessity for interfering with its roof, as was feared. The bone was at least three centimetres thick. The fragments being diseased, it was not desirable to replace them. [The child made an excellent recovery, and two months later a piece of celluloid was inserted to protect the brain. This operation also was followed by primary union.] INTERNATIONAL CLINICS. Ninth Series. A Quarterly of Clinical Lectures on Medicine, Neurology, Surgery, Gynaecology, Obstetrics, Ophthalmology,: Laryngology, Pharyngology, Rhinology, Otology, and Dermatology, and SPECIALLY PREPARED ARTICLES ON TREATMENT AND DRUGS. 5* By Professors and Lecturers in the Leading Medical Colleges of the United States, Germany, Austria, France, Great Britain, and Canada. EDITED BY JUDSON DALAND, M D., Philadelphia, Pa. Illustrated. Price per annum : Cloth, per set, $8.00; Half Leather, per set, $g.00. Each volume contains about 300 pages, octavo, is printed from large, clear type on good paper, and is neatly bound in Cloth and Half Leather. A copious index is contained in each volume ; and Volume IV. of each series contains in addition a general index of the four volumes for the year. Ninth Series commences April, 1899. BY SUBSCRIPTION ONLY. " This work, as the title sets forth, is a collection of the best and most prac- tical clinical lectures delivered in the leading medical colleges of the United States, Great Britain, and Canada. These lectures, after having been reported by competent medical stenographers, are arranged by the editors in a form best suited for the purposes of this work, and afterwards they are returned to the professors and lecturers for their personal revision. The reader is thus given the final thoughts and most advanced practical ideas of our ablest professional teachers. These handsome and well-printed volumes, which are issued with great regularity every quarter, contain a vast amount of instructive and readable matter. The range of subjects is as wide as that of medicine itself, and the lectures upon them are gathered from the clinical schools on both sides of the Atlantic. The publication of such a repertory ot bedside experience cannot fail to exercise a marked influence on thought and practice, whilst the fact that a venture of this magnitude should have attained its seventh year of existence demonstrates that its volumes have obtained a recognized and sure place in periodical medical literature. Each volume contains some fifty or sixty lectures and commentaries upon cases of disease; a certain number of the forms are elaborated into general disquisitions, but the majority are purely clinical-that is, they are based upon cases under observation at the time of the delivery of the lecture. In our opinion, this is the only right form into which a clinical lecture should be cast. It does not and ought not to aim at being an exhaustive survey of the topic with which it deals, such a review should be reserved for the mono graph or thesis ; but it should bring out in clear detail the clinical facts attaching to the patient and deduct therefrom the lessons they convey. " -London Lancet.