STRETCHING OF THE FACIAL NERVE. REPORT OF A NEW CASE, WITH REMARKS, AND A SUMMARY OF PREVIOUSLY REPORTED CASES. BY WILLIAM W. KEEN, M.D., OF PHILADELPHIA PROFESSOR OF SURGERY IN THE WOMAN'S MEDICAL COLLEGE OF PENNSYLVANIA ; SURGEON TO ST. MARY'S HOSPITAL. REPRINTED FROM THE TRANSACTIONS OF THE AMERICAN SURGICAL ASSOCIATION, MAY I, l886. PHILADELPHIA: WM. J. DORNAN, PRINTER. 1886. STRETCHING OF THE FACIAL NERVE. Report of a New Case, with Remarks, and a Summary of Previously Reported Cases. I desire to report the following case of right facial spasm, which existed for five and a half years; and in which resection of the right infraorbital nerve was performed with temporary relief; after which stretching of the facial nerve was done, followed by cure, with lessen- ing paralysis of the face up to date of report. Mrs. A. S., native of England, aged forty-eight years, four feet seven and a quarter inches in height, weighing 138^ pounds, and by occupation a housekeeper, was sent to the surgical clinic at the Woman's Hospital, April 1, 1886, by Dr. Wharton Sinkler, for opera- tion, with the following history: Family : Mother died of dropsy at the climacteric. Father died of inflammation of the stomach. Two brothers were killed in the war. One brother living, but not in good health. Personal: Had nervous trouble when she was a child. Was para- lyzed, and unable to walk until she was six years old, when she was brought to this country, and the sea voyage seemed to restore the tone of her nervous system. When twelve years old was again troubled with loss of nerve power: could not hold anything in her right hand. This condition yielded to remedies in a short time. The menstrual function was established at sixteen years of age. The periods have always been accompanied by a profuse discharge, and a good deal of pain ; they were always regular until about five years ago, when her present nervous trouble began, since which time they recur every two or three weeks, accompanied by an exaggeration of the nervous twitching and pain in the head and arm. From the age of sixteen until five years ago she had no recurrence of nervous trouble, was always healthy, except an occasional sick head- ache, and twice an attack of chills and fever. 4 KEEN, She was married at eighteen years of age, and has had ten children, nine of whom are living. Six months after the birth of the youngest, now nearly six years old, she noticed a drooping of the right upper eye- lid, and soon after a twitching of the under eyelid, and the eyeball was quite bloodshot. Was under treatment for some time without relief. In less than six months the entire right side of the face and the right platysma-myoid twitched constantly ; the angle of the mouth was drawn down and there was constant pain in the head. Talking, eating, and indeed any physical or mental effort increased the spasms. The twitch- ing of the cheek against the teeth made it sore, and the cheek was often caught between the teeth in mastication, so that long since she had all the teeth in the right half of the mouth removed, without any effect on the spasms. She has been under Dr. Sinkler's care from July 23, 1883. Galvanism has been faithfully used, as also other remedies such as conium, gelsemium, cannabis Indica, eserine, nitro-glycerine, iodide of potassium, etc., with no permanent effect. Conium had marked influence on the tic when pushed to full doses, but soon lost its effect. Quinine would relieve the pain in the head when severe. April 25, 1884, Pain in the right leg began, and at times there was pain in the back of the neck and arms. February 2, 1885, she complained of twitching in the right leg. In June, 1884, the right infraorbital nerve was resected by Dr. T. G. Morton. About half an inch was cut out. This was followed by a cessation of all the twitching of the muscles, and the pain in the head was relieved. This relief continued a few days, but by the end of six weeks all the twitching returned, and, in addition later, a twitching of the right side and leg. Dr. Sinkler now sent her to Prof. Keen to have the nerve stretched, as had been agreed would be proper. Physical Examination. Lungs-vesicular murmur good. Heart- mitral regurgitation-murmur heard at the apex and in the axillary space. Urinalysis. Specific gravity 1.028. Color, yellow-white-white de- posit. Reaction strongly alkaline, no albumen, no sugar. April 1, 1886. Present State. Entered the hospital in condition before described. The nervous twitching increased when she was ad- dressed or when she tried to speak. Whether her face twitched during sleep could not be determined, as she awakened on the slightest noise. Given an oil injection in the afternoon in preparation for the operation. 2d. Bowels loose, did not sleep very well through the night. Operation. Began etherizing at 1 o'clock, April 2, Dr. Sinkler present and assisting. At 1.10 an angular incision wasjmade two and a half STRETCHING OF THE FACIAL NERVE. 5 inches long. The angle of the incision was at the apex of the mastoid process, the two lines passing upward behind the ear, and downward in a line parallel with the border of the sterno-cleido-mastoid muscle. Ligated the posterior auricular artery. The parotid gland was dissected and pushed forward till the prevertebral muscles and their aponeurosis were reached. A very weak current of electricity was then applied by a wet sponge to the cheek and a fine wire to various points in the wound until the nerve was found. Immediately a spasm of the facial muscles followed the application. The nerve was then laid bare. A hook was next passed under it and the nerve stretched several times from the face outward, pulling the head over to the right side. When the nerve was stretched, marked contraction of the facial muscles was seen. The force used was estimated at between four and five pounds. No more force was used because a few fibres were felt giving away when an at- tempt was made to lift the head. Horsehair drainage was used and four silver sutures were introduced. Complete paralysis of the facial muscles was noted after the stretching and before she had recovered from the ether. Upon recovering consciousness the patient remarked the absence of pain in the head. Before the operation: pulse 90, temp. 98.8°. After the operation: pulse 82, temp. 98.6°. A carbolized gauze dressing was applied and the operation was com- pleted at 1.50 p. m. On coming out of ether she had four nervous chills. Was given a five grain assafoetida suppository, which quieted her. Took a dessertspoonful of milk or beef-tea every twenty min- utes or half hour through the afternoon. At 6 p. m. complained of severe pain in the ear, which soon passed away. At 7 p. m. vomited, otherwise retained all nourishment. Took short naps through the afternoon and evening. After the operation there was complete paral- ysis of the facial muscles. The right eyelid did not close of itself. Slept very well through the night, snoring loudly. 3d (1st day after operation). 6 a. m. pulse 77, temp. 99.40. Paralysis of facial muscles not so marked as immediately after the operation. No pain in the head, but she complains of a soreness in the right side of leg, which was rubbed with liniment. Took from half an ounce to an ounce of milk every hour, with some coffee. At 1 p. m. pulse 86, temp. 100.40. Gave four grains of quinine. The wound was dressed at 2.30 p. m., slight oozing was found on the dressing. At 4 p. m. pulse 96, temp. 100.40. Felt very comfortable all day and slept soundly all night. 4th (2d day). 6 a. m. pulse 85, temp. 98.6°. Took more nourish- 6 KEEN, ment at longer intervals. Had no pain in the ear. 4.30 p. m. pulse 81, temp. 990. Leg and side still painful, rubbed with liniment. 3th (3d day). 6 a. m. pulse 85, temp. 98.7°. Slept very well through the night, did not snore as on previous nights. Eyelid nearly closed, and facial muscles seem a little less relaxed than before. There has been no twitching of the facial muscles of platysma or leg since the operation. Sat up with bed-rest for an hour in the morning and for twenty-five minutes sat in rocking-chair in the afternoon. 4.30 p. M. pulse 80, temp. 98.6°. 6th (4th day). Temp. 98.4°, pulse 76. Hunyadi water for slight constipation. Out of bed. All the stitches removed this afternoon and the horsehair drainage-a few drops of sanious discharge followed. Bandage removed and adhesive plaster applied. Evening temp. 99.6°, pulse 74. 7 th (5th day). Temp. 98.8°, pulse 73. Complained of pain behind her ear. There was a little discharge through the night. Applied a compress of absorbent cotton with iodoform sprinkled upon it. 8th (6th day), a. m. temp. 98.4°, p. m. 98.4°. Very little dis- charge. 9th (7th day), a. m. temp. 99.90, pulse 73. Able to masticate. Given an enema. Bowels moved. Evening temp. 99°. Was taken unwell. At this period previously the twitching of the face and also of the right side and leg, as well as the pain, were always much worse. All of these are now entirely gone. Neither twitching nor pain is present anywhere. 10th (8th day). Discharged well. 27th (25th day). No twitching or pain. Still complete paralysis, though the eye can be nearly closed. September 10, 1886, five months after the operation, the patient remains well. The facial palsy has almost entirely disappeared, and the face has nearly regained its normal expression. I append the following electrical examination made with great care by Dr. G. Betton Massey : " The under-mentioned muscles of expression of the right side of the face were examined on the tenth day after you had operated-that is, on the 12th of April, and also on the seventeenth and twenty-fourth days after operation. A control examination was at the same time made of the sound side for comparison, and the figures found are placed in the table as the normal formula of each muscle. STRETCHING OF THE FACIAL NERVE. 7 " Farado-contractility was found greatly weakened on the tenth day, and totally abolished on the seventeenth. The galvanic responses tabulated below were noted with great care, all errors from changes in resistance being eliminated by the use of a milliampere meter (Bar- rett's). They were those produced by the minimal current strength at closure of the circuit. " It will be noted by a reference to the table that the frontalis showed the serial change indicative of reaction of degeneration in a slight degree on the seventeenth day. This remained the same on the twenty- fourth, when slight modal change, consisting of a slow wave-like con- traction instead of a sharp, quick one, was noted. The orbicularis palpebrarum showed quantitative diminution of excitability on the tenth day, and serial change on the seventeenth. The levator labii superioris showed slight serial change on the tenth day, which has increased since, amounting on the twenty-fourth day to more than a complete reversal of the normal figures. This was true also of the zygomaticus major, orbicularis oris, and levator menti, in all of which increasing serial change has been found, together with great modal alteration of contraction. The lower muscles of the face show greater change than the upper." Minimal. Contraction at Remarks. Kathodic closure. Anodic closure. f Normal I 1% Frontalis .... J Iot£ 17th day 1/2 I L 24th day I Slight modal change. f Normal % I Orbicularis palpebrarum 4 2/2 2 3 [ 24th day 2% Slight modal change. J- Normal 2^ 3 Levator labii superioris -j day 4 2% 2 L 24th day 3 Modal change. [ Normal 2^ 3 Zygomaticus major . ■ day 2^ 5 3K Modal change. L 24th day 2% Great modal change. f Normal 2% 3 Orbicularis oris J loth d^ 3 Slight modal change. 1% ' Yz Great modal change. L 24th day 1% Great modal change. f Normal 2% Levator menti . . - Iotfj ja^ 1 17th day 2% 3 Great modal change. L 24th day I % Great modal change. The subsequent history, with the later electrical changes, I shall report at future meetings of the Association. 8 KEEN, No. Reporter and method. Reference. Date. Sex, age, and side. Dura- tion of disease. Supposed cause. Temporary result. Final result Remarks. I Baum. (Baum's me- thod.) Berliner klin. Woch., 1878, No. 40, p. 595. July 20, 1878. F. 35 L. 6 years. Epileptic fit. Paralysis disappeared in half an hour; cure for 8-9 mos. Slight return after 8-9 months, another later. After two years so nearly well as not to need a second operation. Great im- provement two years after operation. Right side occasionally twitched. 2 Bernhardt. .Hahn oper- ated. Baum's method). Zeitschr. fiir klin. Med., 1881, p. 96. Nov.i5(?), 1878. M. 36 R. 5 years No paralysis resulted ; twitching returned next day. After two years, all in all, some improve- ment ; often free for hours, at which times active movements do not arouse the spasms. Im- provement not sufficient to en- couragehim to undergo a second operation. Some im- provement two years after operation. Pain preceded the spasms for two years. No electrical difference on two sides. 3 Schtissler. (Baum's me- thod.) Berliner klin. Woch., 1879, No. 46, p. 684, and Godlee's table in Trans. Clin. Soc. xvi. p. 227. Jan. 23, 1879. F. 39 L. 8 years. 9 Paralysis for six weeks, disap- pearing at twelve weeks. Slight return after six months, and growing worse, but in nothing like the previous severity. Some im- provement six months after operation. 4 Eulenberg. (Hueter operated, Hueter's method.) Centralbl. fiir Nervenheilk., 1880, No. 7. and Godlee's table. Dec. 2, 1879. F. 27 L. 2 years. 2 Paralysis for three months, then slowly disappeared, and as. it disappeared the twitchings re- turned, but never so violent as before Some improve- ment three months after operation. • Chiefly sudden and severe bleph- arospasm extending to left side of face, and slightly to right side; also to some spinal acces- sory muscles and flexors of hand and fingers. Schirmer had stretched and divided leftsupra- orbital nerve without result. Posterior auricular nerve not paralyzed by Hueter's opera- tion. Reaction of degeneration followed the operation. Loss of taste in left anterior half of tongue for fifteen weeks. Table of the Recorded Cases of Stretching of the Facial Nerve. STRETCHING OF THE FACIAL NERVE. 9 5 Putnam. (Baum's method.) Archives of Med.,N. Y., Feb. 1881. April 24, 1880. M. 25 R. 3 years. 9 Paralysis disappeared after three months. Spasms returned after nearly a year. Unrelieved nearly a year after the operation. Reaction of degeneration had be- gun on fourth day when first examined electrically, but this disappeared after nine months 6 Bernhart. (Langen- beck oper- ated Hueter's method.) Zeitschr. klin. Med., 1881, p. 99. June 18, 1880. M. 21 L 4 years. Cold Complete paralysis three days. Nearly gone in three months. Gradual return of spasm there- after, but not so severe as be- fore. Somewhat re- lieved four months after operation. Patient would willingly submit to a second operation as the par- alysis was the lesser evil. Re- action of degeneration. Only branches to eye and upper face stretched. 7 Sturge and Godlee. (Godlee operated Baum's method.) Trans. Clin. Soc., London, 1881, xiv. p. 44, and 1883, xvi. 229. July 20, 1880. F. 72 R. 6 years. Mental shock. Paralysis nearly disappearing af- ter three months Slight uncon- scious twitching after three months. At end of nine months, following severe emotional dis- turbance, entire return. Unrelieved three years after opera- tion. 8 Southam. (Baum's method.) Lancet, Aug. 27, 1881, and April 10, 1886. March 28, i88r. F. 59 L. 2 years. Fright. Paralysis disappeared at sixteen weeks. Cure after five years. 9 Hoffmann. Bernhardt, Deutsch, med. Woch., 1882, No. 9, and Godlee's table. March 28, 1881. F. 35 R. 9 Paralysis lasted to some extent till the fall of 1881. At this time, while she was pregnant, and af- ter delivery, spasms were worse, but then subsided (entirely?). Cure or great improvement twenty-five months after operation. Under lip and platysma branches too deep, and were not stretched. IO Godlee. (Bau m's method.) Trans. Clin. Soc., London, 1883, xvi. p. 220. Nov. TO, 1880, left nerve; March 24, 1881, right nerve. M. 36 R. L. 3 years. Paralysis of both sides; began to disappear, after twelve weeks, on each side. As control re- turned, spasms recurred. Unrelieved two years after operation. Left supraorbital nerve was di- vided Sept. 13,1881, for tender- ness, but without good result. II Navratil. Chir. Beit- rage, S. 10. Quoted by Zesas; vide infra. May 15, 1881. F. ? R. 7 years. Slight twitching for three days, then disappeared. Unknown. Not seen later. Slight attack of erysipelas. 12 Putnam. Godlee's table. June 1, 1881. F. 45 L. 9 years. Entire paralysis for two months or more. After several months spasms reappeared. Unrelieved after some months. Supraorbital nerve had been di- vided fruitlessly. 10 KEEN, No. Reporter and method. Reference. Date. Sex, age, and side. Dura- tion of disease. Supposed cause. Temporary result. Final result. Remarks. 13 Southam. (Baum's method.) Lancet, Oct. 8, 1881, and God lee's table. Aug. 1, i88r. F. 32 R. 4 years. Paralysis present after three months, but fading. Cure three months after operation. 14 Benedikt. Wien. med. Presse, 1882, Nos. 13 and 14. July 2, 1881. Old. An old paralysis was followed by secondary tic convulsif for which the operation was done. The lagophthalmia vanished in the eight days of healing. Faradic contractility which had been absentreappeared, and the galvanic approached normal. Improvement about three weeks after operation. Operation was difficult, as it was through the scar of old glandu- lar inflammation; nerve was found thin and gray, and de- generated. 15 Bernhardt. (Hahn oper- ated.) Berliner klin. Woch., 1882, No. 14, and Deutsche med. Woch., 1882, Nos. 9 and 29. Aug. 1881. F. 35 L. 3% years. Persistent drawing with a lens. See remarks. Paralysis disappeared entirely in five months ; twitching began after seven months; after ten months considerable twitching, but not so bad as before. Improvement ten months after operation. Posterior auricular nerve not par- alyzed ; reaction of degenerat'n [Godlee says it "followed lupus which caused contraction of eyelids.'' Bernhardt says it followed " nach anhaltendem Zeichnen mit der Loupe wobei das linke Ange besonders ange- strengt wurde," An amusing error of translation.] 16 Gray. (Baum's method.) Proc. Med. Soc. King's Co., N. Y., 1882, vii. p. T27. May 8, 1882. M. 36 R. 16 years. This was a case of tic douloureux preceded by tic convulsif; pain relieved for four days, then worse than ever; twitching less- ened ; paralysis. Unrelieved as to pain; twitchings im- proved after three months. Reaction of degeneration. '7 Gray. (Baum's method.) do. June 16, 1882. M. 22 R. (L.) 10 years. Only right side stretched; paral- ysis. Cure three months after operation. Both hands also choreic. Re- action of degeneration. 18 Zesas. Wien. med. Woch., 1884, No. 2; and 1885, No. 27. Nov. 16, 1882. M. 37 R. 8 years. Cold. No paralysis followed; spasm lessened, and ceased Jan 4, 1883 [seven weeks], July, 1885, still cured. Cure two years and eight months after operation. No electrical change. Tab le- Concluded. STRETCHING OF THE FACIAL NERVE. 11 '9 Bernhardt. (Levy oper- ated.) Archiv fiir Psychiatric und Nerven- krank., 1884, xv. p. 777. Jan. 16, 1884. M. 25 R. 4% years. Cold. Had paralysis of right face when first seen ; after operation par- alysis much diminished by April 1, 1884. By May 8, spasms returned almost as bad Unrelieved of spasms four months after operation; previous par- alysis some- what im- proved. Reaction of degeneration. as ever. Voluntary power o some muscles had returned. ver 20 Kaufmann. (Hueter's method.) Centralbl. fiir Chirurg., 1885, No. 3. Sept. 16, 1884. M. 61 R. 7 years. Anger. Incomplete paralysis ; improve- ment for four days ; on fifth day returned as bad as ever. Unrelieved four months after operation Only part of nerve stretched. On fifth day same nerve divided without result. 21 Keen. (Baum's method.) Trans. Amer. Surg. Assoc., iv. p. 275. April 2, 1886. F. 48 R 5% years. Nervous trouble coincident with clim- acteric Paralysis ; not lessened when ported (25 days), and with return of spasms. re- no Uncertain; too early to re- port (25 days); [five months after operation still cured; paralysis n early disappeared.] Reaction of degeneration on tenth day. Infraorbital nerve had previously been stretched with- out permanent relief. The most accurate tables heretofore compiled, though not free from errors, are those of Godlee and Zesas. That of Chandler (New York Medical Record, Sept. 9, 1882) is exceedingly inaccurate. Eulenberg has reported only one case, and there is no such case as that of "Germon," while the rose-colored views of the results are not justified by the facts. Dr. Harte, in Agnew's Sur- gery (vol. iii.) has used the tables of Chandler without verification (in that of mimic spasm at least), and has repeated its errors. Moreover, Harte's last four cases should be of the facial, and not the inferior dental nerve. Of these 21 cases there are males, 9; females, ix; unstated, 1. The right nerve was involved it times, the left 7, both 2, and side not stated I. The age is from 21 to 72. Four of them had undergone previous operations (4, 10,12, 21), the first three section or resection of the supraorbital, and the last of the infra- orbital nerve, with no permanent effect. Davidson (Lancet, 28, 1882) stretched the infraorbital nerve in a woman, set. fifty-three, for muscular spasms limited to the muscles of the region supplied by this nerve. The spasms ceased in a fortnight. The case was reported about two months after the operation. 12 KEEN, Remarks.-The operation of nerve stretching was first intro- duced by Billroth and Nussbaum in 1872. It has been done only twenty-one times upon the facial nerve so far as I have been able to ascertain. Five of these cases have been done in America (Putman two, Gray two. My own is the fifth). These twenty-one cases are summarized in the preceding tables. Reason for the Operation. All of the cases have been for more or less extensive tic non-douloureux of the face, lasting from two to ten years. In two cases paralysis of the face pre- ceded the convulsive tic, and in one case tic douloureux fol- lowed the tic convulsif. As Sturge has pointed out, the lesion in tic convulsif is probably central and not peripheral, though Kaufmann's curious case (see p. 286) would seem to show other- wise. In my own case the previous history points almost con- clusively in this direction from the repeated and extensive paralyses. It might be objected, therefore, in limine, that the operation should not be done since it cannot reach the actual seat of the disease, and any interference with the nerve, the mere conductor of motor impulses, would have to paralyze the muscles permanently in order to effect the desired relief. The experiment of Godlee, in which he dissected out the spinal acces- sory and the facial and found that a slight pull on the former was immediately evident on the central side of the short, wide, and straight jugular foramen, while traction on the facial even to rupture of the nerve was not perceptible at the central end of the long, narrow, and curved aquaeductus Fallopii, proves that no central alteration can be urged in favor of the operation on the seventh nerve, although in one case (4) taste was lost for fifteen weeks. But, per contra, while the expected paralysis nearly always follows, it always disappears in time, as I shall show, and the relief of the tic that has followed in a good proportion of the cases, gives a reasonable ground for the operation. Method of Operating. Two methods have been proposed, that of Baum and that of Hueter. In the former the incision is made behind the ear by an angular incision two and a half inches long, the apex being at the apex of the mastoid process. The parotid gland is the first landmark. Its posterior border is STRETCHING OF THE FACIAL NERVE. 13 dissected and pushed forward by a grooved director and forceps till the shining aponeurosis of origin of the sterno-cleido is seen as the second landmark. The interspace between these two is cleared to the depth of one or one and a half inches, when the prevertebral muscles and their anterior fascial covering are the next landmark. The nerve lies in front of this fascia. Some- times the posterior belly of the digastric is seen. The transverse processes of the vertebrae and the styloid process can both be felt and are valuable as additional guides. This space between the mastoid process and the vertical ramus of the jaw is quite narrow and deep. It will barely admit the finger. Hence a good side light is essential, and I found great help from a student lamp and a forehead mirror held by Dr. Sinkler, which illuminated the deeper parts admirably. The chief trouble is to find the exact spot at which the nerve crosses this space on its way from the stylo-mastoid foramen to enter the parotid. Dis- section will always reveal it, but in order to avoid needless injury and abridge the search, I found the use of a weak faradaic current very useful. A strong current at any point in the moist state of the wound will produce muscular spasm at once, but a very weak current will only do so when the nerve is touched. A wet sponge was held on the cheek and the wire end of the other cord was touched at successive points till the nerve was easily detected, when its white trunk was quickly laid bare. While being stretched the extent of twitching produced by it should be noted to see whether the trunk has been stretched on the central side of all the branches. If any branches have escaped, the muscles supplied by them will not twitch when the nerve is stretched, and also, even during etherization, spon- taneous convulsive movements will sometimes recur in the muscles the nerve branches to which have not been stretched, and so point out what branches have escaped. The other method is that of Hueter by an incision in front of the ear two inches long, its middle at the level of the upper part of the lobule. The parotid is at once disclosed. The incision is carried more and more deeply till, at about three- quarters of an inch, one of the two main branches of the nerve 14 KEEN, is reached. Further dissection will soon reveal the second branch and at their junction the main trunk. If it is desired to dissect back to the foramen, a second short incision at right angles to the first must be made posteriorly. Of the two methods, that of Baum is by far the better. In the first place, its scar is hidden by the ear, and especially in a woman this is very desirable. Secondly, it is far less bloody: usually only the posterior auricular artery is cut, and possibly one or two other small vessels; whereas, in Hueter's, there are, usually, a number of glandular branches requiring ligature. Thirdly, much less damage to the gland and other tissues is inflicted. Fourthly, and chiefly, the nerve is reached directly at its emergence from the stylo-mastoid foramen before it has given off any branches except, possibly, the posterior auricular, an unimportant branch. How important this advantage is, is best shown by Kaufmann's case, in which he operated by Hueter's method. His first stretching disclosed the fact that he had not gone far enough back, for the frontalis and orbicularis palpebrarum were not paralyzed. Enlarging the wound upward and downward (it should have been backward) a second stretch- ing gave the same result. On the fifth day the twitching was as bad as ever, and he wished to do Baum's operation, but the patient would not consent to a second scar, so he opened the original wound, found the injected nerve and divided it. The wound promptly healed, but no benefit resulted, and the patient went home worse than he came, for he not only had the twitch- ing but his cheek and mouth were also paralyzed. What light this case may throw upon the pathology of the disease I am hardly able to say. It certainly would seem to point to a peripheral cause for the spasms. In Hoffmann's case also the muscles of the under lip and the platysma were not paralyzed, and in Eulenberg's and Hahn's cases the posterior auricular branch was not affected. I have only had opportunity to compare the two methods upon the cadaver. The result of a score of trials is decidedly in favor of Baum's method, except in the ease of performance from the less room and greater depth, in which particulars STRETCHING OF THE FACIAL NERVE. 15 Hueter's is the better operation. But these should not weigh in view of the reasons before stated. The nerve being found, how shall it be stretched, in what direc- tion, and with what force? I have found an ordinary blunt hook an excellent means, and no other instrument seems necessary. As to direction, I stretched it chiefly from the periphery toward the centre as well as the hook would allow, both because no stretching on the central end would affect the medulla, and because, as Marcus has shown, traction on the central end of a mixed nerve abolished sensibility while traction on the periph- eral end abolished both motion and sensation, and the motor effect was here desired. The amount of force to be used is as yet undetermined. Gray estimated it in his case at six to seven pounds; Southam at four to five pounds; and in my own case it was estimated at four to five pounds. It was not enough to lift the head of the patient (which would probably weigh six to seven pounds), for on care- fully attempting to do this, before the head could be lifted I felt a few fibres giving way and I at once desisted. The head, however, was rolled from left to right quite forcibly. Putnam records an interesting experiment on a dog. The facial has two branches, each about equal in size to the main trunk in man. One of these broke at forty pounds. A much less weight would have broken the nerve in my patient, and in several cadavera injected and condensed by the chloride of zinc the attempt to lift the head caused rupture of the nerve. The dog above alluded to was then allowed to come partially out of the ansesthesia and the other branch was stretched. At seven pounds the motion of the eyelid was impaired, a second pull of eight pounds produced complete palsy, which disappeared on the second day. Putnam recommends that the patient should be allowed partially to recover from the ether to judge of the effects of the pull, and that two pulls of about six and seven pounds be the limit imposed, unless symptoms be so severe that prolonged palsy be desired. My own impression is that this is 16 KEEN, too great a force and that it can be best achieved empirically, the attempt being made to lift the head (six to seven pounds) and being abandoned the moment any fibres give way. In Eulenberg's case the nerve was physically disorganized by the stretching, yet the paralysis disappeared in three months and the spasms returned, though with abated force. Schiissler states that in his case, after three or four pulls, the nerve lay in a small loop in the cavity of the wound, yet the palsy disap- peared in twelve weeks and the spasms partially returned after six months. The effects of slight and of severe stretching differ materially. As has been shown by Haber, Ranke, Cornet, and others, slight stretching either has no influence on the irritability of the nerve or even increases it, whereas greater stretching diminishes it or destroys it. Hence, in cases of facial spasm the stretching should be as severe as the integrity of the nerve will allow. And again the fact that the motor function of a mixed nerve is last lost is an additional reason for the maximum stretching that the nerve will bear. As Weir Mitchell also has shown that a nerve stretched to one-fifth of its length lost its mechanical irritability but not its electrical, but that this last was lost when the stretching reached one-quarter of its length, this is also another reason for the greater degree of stretching. But this stretching should be gradual and not sudden. The fact noted by Billroth that in crutch palsy, which is caused by direct pressure, the motor function is lost while sen- sibility remains, naturally raises the question as to whether pressure might not be advantageously substituted for stretching or, as in Baum's case, combined with it. Stretching first abol- ishes the sensory function, and the motor function last; while pressure reverses this and abolishes the motor function first. Zederbaum's careful experiments {Archiv Physiol., 1883, p. 161) show that in the sciatic nerve of the frog moderate pressure increased the irritability, the maximum being reached at 500 grammes (a little over 1 ounce), but that at 900 grammes (nearly 2 ounces), it began to diminish, and was lost at 1700 grammes STRETCHING OF THE FACIAL NERVE. 17 (nearly 4 ounces). Baum is the only one who has used pressure as well as stretching, but the result was only a partial success. The after-treatment is simple. A few strands of horse-hair suffice for drainage, and with antiseptic dressing, the case should be well in a few days. In my own case the patient was out of bed on the third day; all the sutures were removed on the fourth day, and she went home on the tenth day, having staid in the hospital voluntarily some days more than was absolutely needful. Her highest temperature was TOO.40 on the day after the operation, being normal the next day. Rarely, if ever, should suppuration follow. In Godlee's first case the wound was not healed for six weeks. I think it important to bandage the lower jaw for two or three days, to insure quiet while the wound is healing, and for the same reason to give only liquid food during several days in order to avoid the muscular effort and movements of mastication. Results of the Operation. The operation is free from danger; no death has resulted; no serious complications, and, in fact, no serious illness. Paralysis of the facial muscles, more or less complete both in degree and extent, is always to be expected, indeed desired. But this paralysis has disappeared in every case after a few days, weeks, or months, and in two cases (15, 19) in which prior to the operation paralysis had existed, some degree of voluntary and electrical control was attained. Indeed, this fact, together with the experimental results before referred to as to the effect of moderate stretching in increasing nerve irritability, leads me to suggest that it would be highly proper in some obstinate cases of facial palsy, to stretch the seventh nerve moderately as a therapeutic operation. In Cases 2 and 18 no paralysis resulted, and in Case 1 it dis- appeared in half an hour ; yet, in Cases 1 and 2 there was decided permanent improvement, and in Case 18 a cure lasting for two years and eight months. In such cases as have been examined electrically, the reactions of degeneration have been found, but these have diminished as the nerve was regenerated, and have disappeared after some months. This is also in accordance with the results of experi- mental nerve-stretching in animals in which microscopic ex- 18 KEEN, aminations have been made. More careful observations are, however, needed upon this point. As the paralysis has disappeared and the nerve has regener- ated, in not a few cases the spasms have returned, while in others the relief has extended over years. Hence, the opera- tion maybe regarded from two points of view: (i) as giving temporary relief (palliative) and (2) as giving permanent relief (curative). As a palliative operation the result has been as follows: Case 1. Absolute relief for eight or nine months. Since then great relief (two years). Case 2. Absolute relief for one day. Since then slight im- provement (two years). Case 3. Absolute relief for six months, then return of spasm in lessened severity. Case 4. Absolute relief for three months, then spasms returned with lessened severity (three years and two months). Case 5. Absolute relief for nearly a year, when spasms re- turned. Case 6. Absolute relief for three months, then gradual return of spasms in lessened severity (four months). Case 7. Absolute relief for nine months, then return as bad as ever (three years). Case 10. Bilateral operation. Absolute relief for twelve weeks on both sides, then return of spasms (two years). Case 12. Absolute relief for some months, then spasms re- turned. Case 14. Absolute relief for seven months, then spasms re- turned in lessened severity (ten months). Case 15. Great improvement for three weeks ; prior paralysis lessened. Case 16. Tic douloureux and convulsif both ; pains relieved for four days, then worse than before; spasms somewhat re- lieved. Case 19. Absolute relief for four months, when spasms re- turned with lessened severity. Case 20. Absolute relief for four days; on fifth day as bad as ever (four months). STRETCHING OF THE FACIAL NERVE. 19 Or, in brief, fourteen cases with I. Absolute relief under a week; three cases followed by im- provement for two years in one case and no improvement in the other two. 2. Absolute relief three weeks to four months; five cases followed by improvement in four cases, and no improvement in one. 3. Absolute relief four months to a year; six cases, followed by improvement in three, and no improvement in three. As a palliative operation only, therefore, it is well worth doing, since at no risk of life and but little suffering the relief is often prolonged, and if the spasms return it is with lessened severity. Indeed, my own patient would gladly undergo it again for even the brief respite so far assured, and far prefers a permanent paralysis to the persistent spasms. As a means of permanent cure we have the following: Case 8. Absolute relief for five years. Case 9. Absolute cure or very great improvement (it is not quite clear which) for twenty-five months. Case 13. Absolute relief for three months when last reported. Case 17. Absolute relief for three months. Case 18. Absolute relief for two years and eight months. Or, in brief, two cases of relief, when last reported, for three months, and three of relief for from two to five years. Of the remaining two cases, Navratil's (11) was only followed for three days, and in my own (21), though the result is perfect so far, yet, as it is only twenty-five days since the operation, it is too recent to classify. [Still cured as the proofsheets are corrected, five months after operation.] It would seem, therefore, that whether viewed from the point of palliation or of cure, with our present knowledge, the opera- tion is to be looked upon favorably. Further observation may show its inutility, but when we consider the utter hopelessness of improvement, much less recovery, from any other means, relief by this operation, even if temporary, is had at a very trivial cost, and would be welcomed by any sufferer, while permanent cure is not impossible.