DISEASES OF THE THROAT. REPORT OF DISEASES OF THE THROAT. F. I. Knight, M.D. Harv. trary, the polyp is situated high (at the tip of the epiglottis, for in- stance) to permit it to be seen directly, or when, with the laryngoscope, it is disco- vered in the cavity of the larynx, if its volume occasions slight dyspnoea, if it is implanted in such a manner that its dis- placement cannot lead to an unforeseen ac- cess of asphyxia ; if, in a word, it is possi- ble to prepare the patient, the operation will be performed per vias naturales Laryngotomy for the Removal of Neo- plasms (Krishaber, Planchon, Guyon, Cut- ter, Schwebel, Luschka).—A distinguished German laryngoscopist who has had much experience in the removal of neoplasms from the larynx, recently remarked that he had never performed laryngotomy for this purpose, because he had never had a case in which it was necessary in order to re- move the growTth. Still, there are cases in which it undoubtedly may be necessary on account of the situation of the growth (e.g., in the ventricle of Morgagni), the age of the patient, or some other peculiarity of the case. His remark, however, shows the' great improvements which have been made in the methods of operating per vias natu- rales. Per vias Aetificiales. “ Laryngotomy in cases of polyp of the larynx has hitherto been made very rarely. The proceedings employed are thus classi- fied : We wish, however, in the present article, to lay before our readers some account of the improved methods of laryngotomy, when this operation is necessary. Until the ap- pearance of Krishaber’s article (Diction- naire Encyclopedique des Sciences Medi- cates, 1868), no general laws in regard to the limitation of the operation had been laid down for the guidance of the surgeon. In this excellent article, M. Krishaber says : a. Section of all the parts of the larynx (cricoid, thyroid, the membrane which unites them and the thyro-hyoid mem- brane), plus some rings of the tra- chea. (Ehrmann, Gordon Buck, Gibb, Boeckel). b. Same operation without section of the cricoid (Debron). c. Section of the thyroid alone (Brauers, of Louvain). d. Section of the thyroid and of the thyro- hyoid membrane (Busch, Koeberle). e. Section of the cricoid and trachea (Gilewsky). f. Section of the thyro-hyoid membrane alone (Pratt, Follin).;? “ We have just seen, in considering the two dominant symptoms, that the polyp of the larynx being diagnosticated, the sur- geon, according to the nature of the symp- toms which it establishes, should make, sometimes, direct laryngotomy, sometimes this operation preceded by tracheotomy ; and ought sometimes, on the contrary, to operate per vias naturales.” “ When the polyp is voluminous and, situated in the cavity of the larynx, is liable to cause asphyxia, it is necessary to perform tra- cheotomy. If the polyp is multiple, if its extraction per vias naturales encounters dif- ficulties pertaining to the age or particular condition of the patient, if the nature, even, of the polyp causes a fear that a partial re- moval may cause a rapid multiplication, in all these cases the polyp should be extract- ed per vias artifidales. When, on the con- From a consideration of the cases referred to above, M. Krishaber draws the follow- ing inferences, which, on account of the limited number of cases, diversity of the operations and multiple conditions, he does not claim to be conclusive. “ 1. There are cases where destruction at their seat and removal of polyps of the larynx are impossible per vias naturales, perhaps on account of their volume, per- haps for very many other reasons which we have developed at length. 2. In these cases, two operative proceed- ings may be employed : 2 a. Sub-thyroid laryngotomy, that is to say the section of the thyro-hyoid mem- brane, in case of multiple vegetation, as these have a tendency to recur (pa- pillomata) and as their seat docs not extend below the vocal cords. b. Sub-cricoid laryngotomy, that is to say the section of the tracheo-cricoid membrane, plus the section of some of the rings of the trachea, when the polyp is inserted below the vocal cords. d. Section of the thyroid cartilage and of the thyro-hyoid and crico-thyroid membranes. e. Section of the thyroid cartilage, of the thyro-hyoid, crico-thyroid membranes, and of the cricoid cartilage. f. Section of the thyroid cartilage, of the crico-thyroid, tracheo-cricoid mem- branes, of the cricoid, and of the first rings of the trachea. g. Section of the thyroid cartilage, of the thyro-hyoid, crico-thyroid membranes, of the cricoid, and of the first rings of the trachea. 2. Laryngotomy indirect, comprising:— a. Horizontal section of the thyro-hyoid membrane. b. Horizontal section of the crico-thyroid membrane. c. Horizontal section of the tracheo-cri- coid membrane. d. Section of the cricoid and of the first rings of the trachea.” 3. The section of the cricoid ought never to be practised, whatever may be the seat and volume of the tumor, this being always accessible by the proceedings above or be- low which we have just indicated. 4, The section of the thyroid may be necessary, if the tumor is situated in the ventricle of Morgagni, but in this case alone. This section ought to be avoided under all other circumstances : a. Because the penetrating wounds of the thyroid produce, necessarily, lesion of the vocal cords, however exactly in the median line of the cartilage the operation may be performed. b. Because the wounds of the cartilages- of the larynx (and what we say here has reference, also, to the cricoid) may produce perichondritis and consecu- tive caries. c. Because these cartilages are quite of- ten ossified; because this ossification is ordinarily premature in individuals afflicted by diseases of the larynx, and because it is necessarily a cause of more difficult cicatrization. d. And because, in fact, all the surface of the cavity of the larynx is accessi- ble to the sight and to the touch, with- out the section of any of the cartilages of the larynx. M. Planchon then introduces, in detail, the cases which have come to his know- ledge where laryngotomy has been perform- ed according to one or another of these methods, either for removal of a neoplasm or a foreign body, and from a consideration of these cases draws the following con- clusions : “1. The artificial opening of the larynx has been made by two different proceed- ings : a. Laryngotomy, direct: section of the thyroid cartilage. b. Laryngotomy, indirect: section of the thyro-hyoid, crico-thyroid, or tracheo- cricoid membranes, 2. These operations ought to be practis- ed independently, except in case of lesions extraordinarily extensive. 5. In cases where asphyxia is imminent, tracheotomy will find its immediate in- dication, and the safety of the patient once reestablished by this operation, the surgeon will consider the consecutive proceedings which he should employ following the indications that we have developed in detail.” 3. Tracheotomy will only be performed with laryngotomy when there are special indications. 4. The section of the cricoid cartilage ought always to be avoided. 5. The choice of the operation will be established by the exact diagnosis of the lesion. Dr. Charles Planchon (Fails Gliniques de Laryngofomie, Paris, 1869) adopts M. Krish- aber’s classification of operations with some extension as follows : 6. The section of the thyroid cartilage is not serious as regards life; practised me- thodically, it is not serious for phonation. The ossification of this cartilage is not a contra-indication. The healing will only be slower. This operation may be made every time there is need of access into the cavity, proper, of the larynx. The new artificial passage can be augmented at will by the section of the conoid ligament and “I. Laryngotomy direct, comprising : a. Section of the thyroid cartilage alone. b. Section of the thyroid cartilage and of the thyro-hyoid membrane. c. Section 0f the thyroid cartilage and of the crico-thyroid membrane. 3 of the crico-thyroid membrane, practised transversely perhaps to the right, perhaps to the left of the median line, perhaps on two sides at once. In certain cases of se- rious fracture of the larynx, thyroid laryn- gotomy should be made in preference to tracheotomy. It might be very useful in some cases of obliteration of the larynx consecutive to wounds of the respiratory tube, or certain grave affections of the organ. sufficient to open the larynx at this exact seat. “5. Of all the methods employed up to this time for the extraction of polyps, the operation, of which I have just given the history, is that in which the incision of the larynx is the least extensive. It is to this proceeding that I attribute the cure of the patient. I propose to call the ope- ration I have just described restricted thy- rotomy (thyrotomie restreinte).” 7. Indirect laryngotomy should only be employed in very special cases. The pro- ceeding employed by Follin—section of the thyro-hyoid membrane immediately above the thyroid cartilage—is preferable to the proceeding of Malgaigne, section below the hyoid bone. It will be observed that M. Krishaber has very materially modified his opinion pre- viously expressed in regard to the necessity of injuring the vocal cords, in making section of the thyroid cartilage. M. Krishaber’s paper is supplemented by a report by Dr. F. Guyon, to whom the subject seems to have been referred, which approves of Krishaber’s method of operat- ing in the case reported, and says that thy- rotomy alone gives direct and complete access to the larynx, particularly to the ventricular cavities. It says that sub-hyoid laryngotomy practised according to the in- structions of Malgaigne only gives access to the vestibule of the larynx, that is, to parts accessible per vias naturales, and that furthermore this operation requires exten- sive incision, and that it is only at the bot- tom of a very deep wound that the surgeon perceives, with difficulty, the ary-epiglottic folds and the ventricular bands. When the incision is made nearer the thyroid car- tilage, as was performed by Follin, an easier access is gained to the larynx, par- ticularly to the posterior part. 8. Section of the crico-thyroid membrane, and that of the tracheo-cricoid membrane, are very simple operations, but still more rarely applicable than the preceding.7’ M. Krishaber (La Thyrotomie Restreinte appliquee au polype du ventricule du la- rynx, Paris, 1869) gives a resume of a paper presented to the “ Societe Imperiale de Chi- rurgie,” in which he recommends section of the thyroid cartilage without section of any of the membranes, and containing the details of a case and the following conclu- sions derived from his farther experience : "1. There are cases of polyp of the larynx, in which destruction and extirpa- tion per vias naturales are impossible; in these cases, one can open the larynx direct- ly, obtain its complete cicatrization and the cure of the patient. “2. The choice of the mode of operation will depend upon the tumor and its struc- ture ; the opening of the larynx can be performed on the membranes of the larynx or on one of its cartilages. To reach the larynx by the course fol- lowed by Follin, it is necessai’y to divide a bursa and a cushion of fat often quite ex- tensive, to detach the epiglottis from its inferior attachment and to raise it. Section of the crico-thyroid membrane gives suffi- cient space to introduce a canula or instru- ments, but it does not permit one to see into the laryngeal cavity, it does not ne- cessitate a deep incision, but it exposes to injury the little crico-thyroid artery, hemor- rhage from which is not without gravity, on account of the liability of the blood to run into the air passages. “3. In cases where the polyp is implant- ed in the ventricule of Morgagni, section of the thyroid cartilage must be made. The separation thus obtained is sufficient for the extraction of even a voluminous polyp, without section of the thyro-hyoid and crico-thyroid membranes. The section of this cartilage can be made so as to spare the vocal cords, and then the voice remains intact. The presumed ossification of the cartilage is not a contra-indication although it retards cicatrization. Notwithstanding the fortunate results with regard to the voice which have been obtained by M. Krishaber and others, after section of the thyroid, considering the un- fortunate results obtained by other opera- tors and the results of experiments upon the cadaver, the report does not regard the operation to be without serious danger to the voice, but does not consider this a “ 4. Laryngotomy which consists in the section of the entire larynx, membranes and cartilages, such as has been performed a number of times, ought to be rejected. When, by means of the larynscope the exact seat of the tumor is established, it is 4 contra-indication in cases where thyrotomy is indicated. In regard to the restriction of the operation proposed by M. Krishaber, the report considers that oftentimes in case of multiple sessile polypi, section of the thyroid cartilage alone might not give sufficient room for operation. In all these cases, there is always time, as M. Krisha- ber thinks, to enlarge the incision by divid- ing the membranes longitudinally. Balassa has twice incised the crico-thyroid mem- brane transversely, in order to separate more freely the two parts of the thyroid. This resource could be employed if the separation allowed by the longitudinal in- cision were not sufficient. moval of polypi (Wiener Med. Wochenschr., 28 Juni und Juli, 1865. British Medical Journal, Sept,, 1865), (Planchon). The operation has been done twice since that time by Balassa, and once by Krishaber, whose case, an abstract of which was pub- lished in the Medical Times and Gazette, Nov. 20th, 1869, was remarkable from the fact that the patient spoke with a perfectly normal voice immediately after the operation. Schwebel (These de la Laryngotomie Thyroidienne et de ses Indications, Stras- bourg, 1866, p. 17), sajm the operation of la- ryngotomy being decided upon, if the patient is afflicted with intense dyspnoea, if suffoca- tion appears imminent, one should com- mence by practising tracheotomy and in- troducing a canula in order to -make sure of respiration, or rather should make laryn- go-tracheotomy by an incision of two rings of the trachea and of the cricoid cartilage. When, on the contrary, it has been decided to operate on a polyp which has not caused very serious trouble in respiration, and when asphyxia is not imminent, one can proceed to thyroid-laryngotomy without preliminary tracheotomy. It has been sufficiently demonstrated that simple thyrotomy gives sufficient space for operation within the larynx, for operators to impose upon themselves the rule only to pass the limits of the cartilage, when, in the course of the operation, necessity com- pels them to do so. Dr. Cutter, in a monograph entitled, Thyrotomy for the Removal of Laryngeal Growths, Modified (Boston, 1871), recom- mends, “ In the operation for the removal of growths in the larynx by section of the thyroid cartilage to hold the use of trache- otomy and the tracheotomy tube as a re- serve measure.’7 Dr. Cutter is certainly entitled to all the merit of originality in this method of operating, for he seems not to have been aware of the operations of pure thyrotomy which preceded this ; but we cannot call it the “ American method,” as it was done by others before he did it, and has been performed about an equal number of times in this country and in Europe, for the removal of growths, not taking into account the numerous opera- tions of this kind for the removal of foreign bodies. The first operation of simple thy- rotomy of which we have any record was performed by Brauers de Louvain, in 1833 (Krishaber, Diction. Encyc., p. 162). Deb- ron reported a case to the Societe de Chirur- gie de Paris, March 30th, 1864 ( Gazette des Hopitaux, 1864, Nos. 76, 87, 88), (Krisha- ber), in which he attempted sub-hyoid laryngotomy, was obliged, on account of threatened asphyxia, to perform thyrotomy and finally to perform tracheotomy, the cricoid cartilage having been left intact. Koeberle (Gazette des Hopitaux, Jane 7th, 1866j, reports a case in which he performed “ Laryngotomie d’emblee sans Tracheoto- mie,” for the removal of a growth, June 19th, 1865. In Dec., 1864, Gilewski made a section of the thyroid cartilage and of the crico-thyroid membrane for the re- Laryngotomia Thyreoidea Lateralis. Luschka (Der Kehlkoph des Menschen, Tubingen, 1871, p. 19) suggests this ope- ration which has thus far only been per- fox-med on the cadaver. It is recommended, in case of neoplasm in the ventricle of Morgagni, when, from any cause, median thyrotomy does not seem advisable, or in case of any affection of the wall of the ven- tricle, removable by operative procedure. By this operation, it is proposed to open the ventricle of Morgagni without expos- ing the vocal cord or its muscle to any danger of injury. This suggestion is founded on the well known fact, that the ventricles of the larynx extend upward on each side to the neigh- borhood of the upper border of the lateral wings of the thyroid cartilage. The long axis of the ventricle runs nearly in the direction of a vertical line, drawn between the first and second quarter of the horizontal distance, between the incisura thyreoidea superior and the posterior bor- der of the thyroid cartilage. This vertical line indicates the direction of the incision for lateral thyrotomy, in the execution of which it is necessary to divide the skin, the muse, sub-cut. colli, the muse, sterno- hyoideus, as well as the thyroid cartilage from top to bottom. After the edges of the cartilage have been drawn asunder by blunt hooks, the upper end of the ven- tricle of Morgagni comes into view in such 5 a manner that there is no difficulty in con- tinuing the incision through its lateral wall as far as the level of the upper surface of the vocal cords. sion of the Vocal Cords.—Dr. M. J. Ross- bach ( Virchow’s Archiv, April 11th, 1872) reports two cases of special interest with reference to the physiology of the voice, in which, during partial paralysis of one vocal cord, there were produced two tones instead of one, clearly distinguishable from each other. One tone had always the cha- racter of a chest-tone, the other that of a falsetto, Thq affected cord was seen to be stretched somewhat, but was not rendered so tense as that on the sound side. On at- tempted phonation, the arytenoid cartilages were not brought up quite to the median line ; hence there was not a complete clo- sure of the glottis. Dr. R. says that this formation at the same time of two tones by two unequally stretched cords, which, of course, were much weaker and less clear than a normal tone, admits probably of no other interpretation than that they have been formed by the vibrations of the vocal cords themselves. For, during the process of phonation the chink of the glot- tis was several millimetres wide and the processus vocales of the arytenoid carti- lages did not even touch each other, so that there could be no interrupted currents of air. Then, again, it is hard to think that one and the same current of air, set into un- equal vibrations by not equally rapid move- ment, should be divided into two tones. Dr. Mackenzie, in a letter {Lancet, Dec. 2, 1871), replying to certain remarks of Mr. Durham in the Royal Medico-Chirurgi- cal Society, reiterates the opinion expressed in his Essay on Growths in the Larynx, considering it “a cardinal law that an extra laryngeal method ought never to he attempted (even when laryngoscopic treatment cannot be pursued), unless there be danger to life from suffocation or dysphagia.” Perichondritis Laryngea.—A case is re- ported in the British Medical Journal, July 13th, 1812, which seems to have been one of perichondritis laryngea; it occurred at the Hull Infirmary under the care of Dr. G. F. Elliot. The case is remarkable from its having occurred in a robust man with- out any history of syphilis or other consti- tutional disease, and from its having re- covered without any necrosis. Ten weeks before admission, and shortly after the ces- sation of what seemed a slight cold, the patient noticed a difficulty in swallowing, and also that respiration was somewhat ob- structed, especially on making any exertion. When these symptoms had existed for about a month, he observed that his neck was harder and larger than natural, and this continued gradually to increase. On his admission, the most noticeable feature was the great increase in the antero-posterior diameter of the neck ; the swelling was evidently situated in the thyroid cartilage ; it was hard, painless on pressure, and pre- sented no indication of suppuration. He was ordered an iodide of potassium mix- ture, and the local application of iodide of ammonium ointment. On the 28th of Feb- ruary, he was suddenly seized with a com- plete obstruction to respiration. Mr. Plax- ton, the house-surgeon, having been imme- diately summoned, with great promptitude opened the trachea, and respiration (all at- tempts at which had ceased) was happily restored by intermittent pressure on the thorax. The necessary incision gave vent to a quantity of somewhat glaiz-y-looking pus. From this time, the man’s improve- ment was uninterrupted, the swelling of the neck gradually subsided, and the thick- ened thyroid cartilage became nearly re- duced to its natural dimensions. The tube was removed on the 7th of May, rather more than two months after its incision ; the opening rapidly closed, and on the Ilth of May, he was discharged, well. Cases have been reported by Merkel and Tiirck in which a double tone was produced by a collection of mucus between the vo- cal cords and ventricular bands, and by growths and polyps on the vocal cords, dividing the glottis into unequal parts, but the above are the first cases reported in which a double tone was produced by une- qual tension of the vocal cords. Papilloma of the Larynx; Warts on the Hands.—Dr. Paluce de Marmon (iV. Y. Med. Record, Oct. Ist, 1872) reports the case of a patient 51 years of age, who had had whooping cough at 4, lasting four or five months. This was followed by hoarse- ness and aphonia. A homoeopathist had told the parents that the child “ would out- grow it.” Instead of this, however, it died suddenly of asphyxia. On post-mor- tem examination, a large papillomatous growth was found in the larynx. There were also half a dozen warts on the backs of the hands. Dr. M. is inclined to think that there was a connection between the two growths. Primitive Cancer of the Larynx.—Dr. Emile Blanc (Etude sur le Cancer primitif da Larynx, Paris, 18V2), at the end of his Double Tone of the Voice in unequal Ten- 6 monograph, draws the following conclu- sions : fulfils its mission, which is to soothe if not to cure.” “1. Primitive cancer of the larynx is a rare affection ; the number of observations of laryngeal tumors in general, hitherto published, is very considerable ; that of cancer of this region is limited to less than thirty. The Electrolytic Treatment of Naso-Pha- ryngeal Polypi.—Dr. Paul Bruns, assistant in the surgical clinique at Tubingen, in an arti- cle on this subject (Berliner Klin. Woch- ensch., July 1,1872), reports a case* treated in the clinique of his father, a short notice of which has already appeared in the latter’s work on “ Galvano-Chirurgie.” A young man nineteen years of age, with a large nasb-pharyngeal polypus, appeared at the clinique in November, 1865. Treatment by means of Electrolysis was attempted, but given up after six applications on account of want of noticeable improvement and of the proper apparatus. In December, 1866, the tumor was extirpated by means of a wire sling, but there remained a small part, which could not be immediately removed on account of profuse bleeding and faint- ness. The patient appeared again at the clinique towards the end of the year 1868. The tumor had grown to a much greater size than before the extraction. “2. The point of origin and the seat of election of cancer of the larynx, is espe- cially the mucous membrane of the ventri- cle of Morgagni. “ 3. The principal varieties of cancer of the larynx are medullary cancer and epithe- lioma. “ 4. Left to itself, cancer of the larynx invades the neighboring tissues, contract- ing the respiratory passages and those of deglutition. The cartilages of the larynx oppose for a long time the progress of the disease, but they end by being involved in their turn, and then the progress of the tumor is arrested only by the death of the patient. “5. At the beginning of the affection, in spite of the most careful laryngoscopic ex- amination, it is very difficult to recognize the cancerous nature of a laryngeal tumor. Later, the rapid extension and the peculiar aspect of the neoplasm, the ganglionic en- gorgement and the final cachexy make the diagnosis certain. It now caused a very considerable dis- figurement of the face, which was notice- able at the first glance. Nearly the whole of the left half of the face appeared pushed up, the left half of the nose was noticeably broadened, the left nostril much dilated and filled up by a pale-red smooth swelling. The fossa canina and temporalis of the same side were filled up, the whole cheek pushed forward. The globe of the left eye stood several lines farther forward, and was at the same time displaced outwards and downwards. In consequence of this, there existed diplopia, incomplete closure of the lid and impaired action of the internal rec- tus muscle. “ 6. The treatment recognizes two prin- cipal indications : a. To remove the disease. b. To palliate the most urgent symptoms and especially the threatening of asphyxia. This last indication is fulfilled by tracheoto- my, the first by the extirpation of the tu- mor. According to the case, this removal is practised by the mouth or by different procedures of laryngotomy. The pharyngeal cavity was nearly com- pletely filled up with a very resistent tumor, which pushed forward between the edges of the artificial slit in the soft palate, which was made previously to the first operation, into the mouth and downwards as far as the lower end of the uvula. “ Laryngotomy is always indicated when the tumor is not accessible by the natural passages, or when by this latter means we do not succeed in the total destruction of the neoplasm. In conclusion, however well practised and however radical it may be, extirpation is constantly followed, some- times by local recurrence, sometimes by secondary generalization, and finally by death by cancerous cachexy. Always, if one does not succeed in saving the life of the patient, at least he mitigates and pro- longs it. It was thus that in the case ob- served by M. Desormeaux laryngotomy permitted the subject to survive for three years. Here, then, as in other analogous circumstances, surgical art by interfering Both nostrils were impervious to the air, the left in consequence of complete stop- page by the nasal part of the polypus, the right in consequence of the pushing of the septum towards this side, and the closure of its posterior opening by the growth. Respiration and deglutition were rendered * An allusion to this article has been already made in the report on Electro-Therapeutics, Oct. 31, 1872, but the great importance of any aid in treating this most troublesome affection leads me to give the details of Dr. Bruns’s case, and some particulars not given by Dr. Lin- coln. 7 difficult. Hearing on the left side and the sense of smell were entirely lost. There existed also a condition of great general debility and frequent somnolency. From the above appearances the diagnosis of a so called retro-maxillary tumor (Langen- beck) was made, the extirpation of which it was thought could only be made by means of a temporary (osteoplastic) resec- tion of the upper jaw. Instead of this, the attempt to destroy the tumor by electro- puncture was repeated, and this treatment was commenced May 2d, 1869. The elec- trolytic treatment was continued to the end of March, 1810, and during these eleven months there were made one hundred and thirty applications, sometimes daily and sometimes at the interval of one or several days. The duration of one application was ten to fifteen minutes. After the first sit- ting, the left nostril was a little pervious to the air; after the tenth sitting, there was an evident diminution in the size of the pharyngeal part of the polyp. It continued gradually to diminish in size, and after forty sittings the anterior end of the nasal part was three centimetres removed from the edge of the nostril. There was notable im- provement in breathing through the nose, the globe of the left eye was less promi- nent, its movement less hindered, and there was no diplopia. After sixty sittings no exophthalmos existed; the nasal part of the tumor was four centimetres from the nasal opening. After eighty sittings the polyp was five centimetres from the nasal opening; the pharyngeal part was no longer visible in the cleft of the palate, and could only be reached by means of a curved needle. After one hundred sittings, by rhinoscopic examination there was seen in the remainder of the tumor, which was of the size of a walnut, a deeg ulcerating hole covered with purulent secretion which was soft to the touch, friable, and surrounded by resisting edges. After one hundred and thirty sittings, at the conclusion of the treatment, the outward deformity of the face, the prominence of the whole left upper half of the face, and the dislocation of the globe of the eye had disappeared. Both nostrils were pervious to the air, the nasal part of the polyp had entirely disappeared, the pharyngeal part was no longer visible in the cleft of the palate, and only a hard knot of the size of a bean remained on the posterior edge of the vomer. .Respiration and deglutition were unimpeded; hearing in the left ear was nearly normal. Up to March, 1872, there had been no sign of a recurrence of the growth in this patient; he had remained in the hospital as an atten- dant. Dr. Bruns then gives abstracts of eight other cases of naso-pharyngeal polypi, which had been successfully treated by electrolysis. Five had been observed by Nelaton, two by Ciniselli, and one by Fischer. In six of these, there was a complete cure, and in the remaining two the cure was incomplete ; in the first in consequence of intercurrent typhus fever, which proved fatal, and in the second because the report was made before the conclusion of the treat- ment. In none of these cases had a recur- rence occurred. The duration of the treat- ment in those cases where it is stated, is reported to have been as follows : six sit- tings, nine sittings at long intervals, six sit- tings within six weeks, and six sittings within about three months. In these cases, where the application was made at such long intervals, the current employed was of much greater intensity than in the case of Professor Bruns. In one of Nelaton’s cases an operation had been previously performed by means of re-section of the hard palate, and there was a recurrence of the growth after three months. Eight months after the cure by electrolysis, there had been no recurrence. Dr. Bruns does not claim that this method of treatment can be employed with success in all cases, and, indeed, mentions a case already reported by himself [Berliner Klin. Wochenschr. 12 u. 13, 1812), in which, after unsuccessful employment of electrolysis, extirpation was performed. The histological character of the tumors successfully operated upon by electrolysis seems to have been fibrous ; in the one un- successful case the tumor is described as being composed of a tissue in part purely fibrous, and in part very rich in cells ap- proaching the sarcoma. Contrary to the custom in the treatment of tumors situated in other parts of the body, experience seems to show that it is better to employ a weak current, frequently repeated, than a strong one at longer intervals ; the close proximity of the brain and the serious local disturbance which might be set up by the strong current, would indicate caution in this respect. Dr. Bruns does not consider that in any base a diminution of the tumor was due to catalytic or escharotic action alone, but to both combined. In conclusion, Dr. Bruns says that there is inducement enough in pre- vious experience to warrant the employment of electrolysis in other cases, even if we 8 cannot share the enthusiasm of Dolbeau, who characterizes its employment as “ une methode qui parait destinee a faire dispa- raitre toutes celles qui I’ont precedee.” nodular varieties. The treatment which has been found most successful in this va- riety by Dr, M., is the introduction of a twine seton passed transversely through the whole substance of the gland.' On the Differential Diagnosis and Treat- ment of Bronchocele.—Dr. Morell Macken- zie (Lancet, May 4th and 11th, 1872) gives an interesting paper on this sub- ject, which he had read before the Hunteri- an Society. Counter-irritation, or applications of tincture of iodine or iodine ointment, or the injection of a solution of iodine, have proved quite unavailing. Out of one hun- dred and one cases of the fibrous varie- ty which came under notice, in thirty-one the tumor was so small and the inconve- nience so slight that treatment was not recommended; and nine patients, who were told that the disease was not dangerous to life, declined treatment. Of the remaining sixty-one, in forty-two the result was com- pletely successful. In eleven, there was considerable improvement ; in five, no change, and in three the parties ceased to attend before the result could be ascer- tained. In the two illustrative cases intro- duced by Dr. M., the dyspnoea was relieved within a day or two after the introduction of the seton. He says that since Coindet discovered the medicinal value of iodine, the therapeu- tics of goitre have - remained almost sta- tionary. Whilst, however, iodine exercises such a beneficial influence over some forms of goitre, in others it is quite inoperative, and hence it becomes important to differ- entiate the varieties of the disease which are met with in practice. Dr. Mackenzie divides bronchocele into seven varieties, viz. : (1) simple or adenoid, (2) fibrous, (3) cystic, (4) fibro-cystic, (5) fibro-nodu- lar, (6) colloid, and (7) vascular. The disease may present the characteris- tic features of any one of the types referred to, or many of the different varieties may be associated together in varying degrees. The internal administration of iodine is a specific for the endemic variety of simple or adenoid bronchocele; and, though it likewise often cures sporadic cases, it is fre- quently unavailing. The treatment of cystic goitre which Dr. M. likes best, is the conversion of the cyst into a chronic abscess. The treatment which most rapidly produces suppuration also most effectually arrests the haemor- rhage. The method of procedure is as fol- lows: Ist. Empty the cyst; when prac- ticable, make the puncture as near as possi- ble to the median line in the most dependent portion of the tumor. As soon as the trocar is felt to pierce the cystic wall, it should be withdrawn and the canula passed further in by means of a blunt pointed key. The fluid having been withdrawn, a solution of per-chloride of iron (two drachms to the ounce), is injected through the canula by means of a syringe, the plug is inserted, and the canula secured in position by a strip of plaster. Tl*e injection of iron is repeated at intervals of two or three days until sup- puration is established. When this point is reached, the tube is withdrawn, poultices are applied, and the case treated as a chronic abscess. When there is more than one cyst, the others can frequently be opened through the cyst originally punc- tured, and in this way some scars may be avoided. Of thirty-nine cases of cystic goitre, thirty-eight underwent treatment; all of these were completely cured. Simple hypertrophy occurring in weak anremic girls, is most effectually treated by iron and proper hygienic measures. Cases not yielding to internal treatment may al- most invariably be cured by counter-irrita- tion, or the internal and external treatment maybe combined. The liquor epispasticus of the British Pharmacopoeia, applied about twice a week on alternate sides of the throat, is the remedy which Dr. M. usually employs. Electrolysis had also proved of great service in some cases. Of the fifty- four cases of simple goitre of which notes were taken, forty-seven underwent treat- ment. In thirty-five the enlargement en- tirely disappeared, five were lost sight of after a few visits, and in seven no appreci- able alteration took place. Fibrous Bronchocele may. attack either lobe, the isthmus, or the whole gland, but it is comparatively rare that the isthmus alone is affected. To the touch fibrous goitre is smooth, hard, and unyielding. It does not, as a rule, cause any disturbance of function, but in some cases it presses on the trachea and produces dyspnoea. When once established it never disappears spon- taneously, though it may occasionally be developed into the fibro-cystic or fibro- The treatment of a case of fibro-cystic goitre consisted in the evacuation of the cysts and the injection of iron, and after the obliteration of the cysts, the introduc- tion of a drainage-tube, from left to right, through the entire mass. 9 Great induration remaining, two caustic darts were introduced. By this treatment the circumference of the throat was reduced five inches and a half. least, causes no dyspnoea, but complete loss of voice, difficult expectoration and impossibility of forcible cough. There is the same want of dyspnoea in complete pa- ralysis of the recurrent on one side. This is easily explained from the position of one or both vocal cords in these cases. With reference to this point, the views of differ- ent authors seem to differ considerably. Many pathologists have spoken of paraly- sis of the recurrent when the paralyzed vo- cal cord is displaced nearly or quite up to the median line. Such a conception seems to Riegel to be erroneous. Complete pa- ralysis of the recurrent can never result in a position of the vocal cord exactly on the median line. He does not deny that such a median position can be the consequence of an affection of the recurrent, as a neuro- pathic paralysis; but in the peculiar me- dian position of the vocal cord there is never a paralysis of all the muscles of the larynx.* In fibro-nodular bronchocele, treatment has seldom any beneficial effect. Of two reported cases of colloid bron- chocele, one was treated by electrolysis, and the other by a seton, both unsuccessfully. Dr. M. thinks that with his increased expe- rience both of these cases might have been successfully ti’eated by irritating setons or caustic darts. No case of the vascular form of bron- chocele occurred. The rule which Dr. Mackenzie has adopted with reference to the advisability of surgical interference in cases of goitre is, not to •recommend patients to undergo treatment unless there is serious embarrassment of function or continuous increase of the tumor ; but, as none of the various methods of treatment employed by him have hitherto been attended by fatal results in his practice, he has always been willing to carry out treatment when the patient desired it, on account of disfigure- ment. From this position of the glottis in com- plete paralysis of the recurrent, the want of dyspnoea, at least under ordinary cir- cumstances, is easily explained. The me- dian position, however, pre-supposes an activity of the vocal cord ; it can only oc- cur through action of the adductors, and, therefore, can never he observed in com- plete paralysis of the cord. Neither is much dyspnoea possible in this form of pa- ralysis, as there is still sufficient room for inspiration and expiration, as the glottis now in a manner assumes a mean position, the resultant of those two positions, which correspond to the two functions of vocali- zation and respiration. The same thing must naturally hold good for complete pa- ralysis of the recurrent on one side. Here, the conditions for the production of dysp- noea are still more unfavorable. If we ask, on the contrary, which form of paralysis of the vocal cords produces dyspnoea, it is evidently the paralysis of the adductors. This form, also, of paralysis, like the com- plete paralysis of the recurrent, can occur on one or both sides. Paralysis of the abduc- tors, while the adductors remain intact, is not followed by a mean position of the vocal cords and arytenoid cartilages. One would here, indeed, expect the same position as on the cadaver, with the possibility of ap- proximation to the median line on intona- tion. Observation shows, however, that this does not occur, or at least such a con- dition has not been seen in those cases which have been considered paralysis of the abductors. The picture of paralysis of Paralysis of the Abductors of the Vocal Cords.—Dr. Franz Riegel, Privat-Docent and First Assistant in the Medical Clinique at Wurzburg (Berliner Klin. Woch., May 18th and 20th, 1812), says that paralysis of one or a few muscles of the larynx is sel- dom met with; but when it does occur, it is generally myopathic ; much more rarely does it happen that only a single muscle or a small group of muscles is paralyzed in consequence of a central lesion, or one af- fecting the vagus and recurrent. He be- lieves the opinion of Gerhardt, that, in case of an affection of the recurrent only, a sin- gle group of muscles may be paralyzed, namely, the adductors and tensors, to be correct, notwithstanding the opposition of Navratil; and refers to a case reported by himself* in which paralysis and change in the voice came on immediately after an op- eration in a case of struma, evidently from injury to the recurrent nerve. The paraly- sis affected only a part of the muscles of the vocal cord on the side of the injury ; the widening of the glottis was completely unimpeded. Those cases in which the pa- ralysis is incomplete must not be consi- dered as myopathic ; for in an affection of the recurrent the paralysis may be incom- plete at first, and afterwards become com- plete. It seldom happens that paralysis of the vocal cords, under ordinary conditions, leads to disturbance of the respiration. Complete paralysis of the recurrent on both sides, under ordinary circumstances, at * Deutsches Archiv far Klin. Med., Band 6. * Complete paralysis of all the muscles of the larynx will produce only the post-mortem position of the vocal cord, and the ary tenoid cartilage. 10 the abductor is characterized as follows : The vocal cord and arytenoid cartilage of the affected side stand near the median line immovable ; on deep inspiration, the cord does not move outward, but sometimes a little inward; its capacity for tension and vibration is not materially limited ; the voice, therefore, shows no essential change. It may be easily conceived how, on rela- tively little exertion, dyspnoea can arise from this median position of the paralyzed vocal cord. As the glottis-chink is dimin- ished by one-half, the increased demand for air during any marked bodily exertion can- not be satisfied, and dyspnoea is the result. The only abductor of the vocal cord is the crico-arytenoideus posticus. Paralysis of the abductor, therefore, is paralysis of this muscle. Paralysis of the abductors on both sides occurs very rarely. muscles, the limb is drawn gradually to one side. But in the larynx. Dr. Riegel thinks a negative factor is more important. When the vocal cord, in case of paralysis of the abductor, is brought into a state of adduction by intonation, cough, expectora- tion, &c., the power to widen the glottis again is wanting ; the cord retains the po- sition into which it has been brought, with the exception of what change may be due to a relaxation of tension. In case of total paralysis of an extremity, the flexors overcome the extensors. In the larynx, on the contrary, respiration being a more im- portant function than vocalization, we see the abductors overcome the adductors in case of complete paralysis. Hence the considerable drawing outward of the cords. If, on the contrary, only the abductor is paralyzed, the adductors obtain the prepon- derance, and hence a position results near the median line. This last position may only be arrived at gradually. Dr. Riegel alludes to the great rarity of bi-lateral pa- ralysis of the abductors, and says that Gerhardt’s case is the only other true one which has been published ; one or more cases, however, have been published by Mackenzie, and two by the writer.* After citing the cases of Gerhardt, Tiirck and JBiermer, Riegel introduces one of his own, in which there was paralysis of the crico-arytenoideus posticus on each side. The patient, a child 4 years old, was said by his parents frequently to throw hjs head strongly backwards and stretch his throat. On increase of dyspnoea, this position was particularly noticed by his parents. A sim- ilar condition obtained in Gerhardt’s case, who explained this by the power of the hyo-thyroideus, as antagonist of the crico-thyroideus, to approximate the thy- roid cartilage to the arytenoids with relaxa- tion of the vocal cords, and so to diminish the contraction of the glottis caused by tension of the same. The question remains how the position of the vocal cords, which has been mentioned as occurring in case of paralysis of the abductors, is produced. According to theory, paralysis of the ab- ductor, like complete paralysis of the re- current, would manifest itself by the ordi- nary post-mortem position of the vocal cord. It would then be distinguished from complete paralysis of the vocal cord by the existence of the power of adduction, and from paralysis of the adductor from the want of ability to move outward from the post-mortem position. Instead of the post- mortem position, however, we find the vocal cords much nearer.the median line. We see, therefore, an increased activity of the antagonistic muscles, as we see a pre- ponderating contraction of the flexors in paralysis of the extensors. So we can designate this appearance as paralytic con- traction of the vocal cord in the same way as we notice the secondary contractions in paralysis of the extremities. The occur- rence of such contractions in case of paraly- sis has been accounted for by the so-called antagonistic theory, whereby, in conse- quence of the tonicity of the non-paralyzed Successful Tracheotomy performed on a Child of Ten Months (Union Medicate, 1812, No. 18); (Centralblatt fur die Med. Wissenschft, Aug. 23, 1812). Dujardin re- ports a case of croup in a child ten months old, in which tracheotomy was performed. It was necessary to wear the canula eight months. Now, after four years, a small, tracheal fistula exists. The reporter in the Centralblatt says this is the sixth success- ful case of tracheotomy in children under eighteen months reported in France. A Eemedy for Coryza.—E. Brandt (Ber- liner Wochenschrift. No. 12 and 18) ; ( Gen- tralb. fur die Med. Wissensch., No, 29, 1812) reports that for many years he had suffered every autumn with intense coryza,_lastiug several weeks, and that he has obtained a very favorable effect from the “ Olfactorium Anti-catarrh-oicum;; of Dr, Hager (acid carbol. 5 parts, spir. vini rectif. 15, liq. ammonim fort. 5, aq. dest. 10) inasmuch as the coryza was cured after one day’s ex- istence in the first stage, and without, as formerly, invading the trachea. A few drops of the mixture should be poured on blotting paper and inhaled, care being taken to protect the eyes.f * Boston Medical and Surgical Journal, Feb. 25th. and Sept. 30th, 1869. f Writers of papers on the Diseases of the Throat and Chest will contribute much assistance in the preparation of the semi-annual reports in this department if they will forward copies of their papers, addressed to this Journal.—Eds.