The Therapeutical Applications 
OF 
Peroxide of Hydrogen 
(MEDICINAL), 
and Glycozone 
BY 
CHARLES MARCHAND, Chemist, 
GRADUATE OF THE "ECOLE CENTRALE DES ARTS ET MANUFACTURES 
DE PARIS'" (FRANCE). 
TREATMENT OF DISEASES CAUSED . 
BY 
GERMS, BACTERIA, MICROBES. 
REVISED EDITION. 
NEW YORK 
1890. 
[ Copyright secured.} CONTENTS. 
Page 
Action of Marchand's Peroxide of 
Hydrogen (medicinal) upon infected 
surfaces 7 
Anthrax-Carbuncle-Treatment .... 32 
Asthma-Treatment by ozonized vapor 
inhalations 20 
Bronchitis-Treatment by ozonized 
vapor inhalations 20 
Catarrh of the Nose and Catarrh of 
the Throat-Treatment 10 
Caution 20 
Comparative chemical reactions be- 
tween Marchand's Peroxide of Hy- 
drogen (medicinal) and ozone 4 
Comparative tests of different anti- 
septics 8 
Consumption-Causes ; Bacillus Tu 
berculosis-Treatment by ozonized 
vapor inhalations 23 
Croup-Causes and treatment 25 
Definition of pathogenic micro-or- 
ganisms, according to Prof. Koch.. 1 
Destructive action of ozone upon the 
virus 3 
Diphtheria-Causes, and successful 
treatment by Marchand's Peroxide 
of Hydrogen (medicinal) 26 
Directions for using Marchand's Hand 
Atomizer and Ozonizer 19 
Diseases caused by germs-bacteria. . 2 
Dyspepsia-Treatment by Glycozone. 27 
Epidemy is caused by the absence 
of ozone in the atmosphere 3 
Gastritis-Catarrh of the Stomach- 
Causes, and successful treatment by 
Glycozone 29 
Gonorrhoea - Gleet - Treatment by 
Marchand's Peroxide of Hydrogen. 34 
Hay Fever-Rose Cold-Coryza- 
Causes and treatment 13, 14 
Important information on Peroxide of 
Hydrogen (medicinal) 5 
Inflammatory diseases of the eyes- 
Treatment by Glycozone......... 38 
Page 
Inhalation of oxygen and the so-called 
compound oxygen (foot-note). Opin- 
ion of Dr. Karl von Ruck,B. S., M. D. 7 
Laryngitis-Treatment 25 
List of diseases successfully treated by 
Marchand's Peroxide of Hydrogen 
(medicinal) and Glycozone 35 
Marchand's Hand Atomizer and Ozo- 
nizer, cuts and description 16 
Nose, Throat and Chest Diseases.... 10 
Opinion of the medical profession.... 42 
Ozone cannot be produced industrially 
in large quantities 3 
Ozoena-Treatment 12 
Pharyngitis-Treatment 25 
Relations of bacteria to disease 1 
Scarlet Fever - Causes - Antiseptic 
treatment by Marchand's Peroxide 
of Hydrogen (medicinal) 30, 31 
Sore Throat-Quinsy-Tonsilitis, and 
all inflammatory diseases of the 
throat-Treatment.- 24 
Suppurative diseases of the ear- 
Treatment by Glycozone 40 
The dangers of carbolic acid. Results 
of experiments (foot-note) 9 
Testing process for the solution of 
Peroxide of Hydrogen (medicinal) . . 6 
The use of Marchand's Peroxide of 
Hydrogen (medicinal) in dental sur- 
gery-General Directions 36 
Typhoid F e v e r-Causes-Mar- 
chand's Peroxide of Hydrogen 
(medicinal) used as a preventive for 
Pyaemia and Septicaemia 31. 32 
Ulcer of the Stomach-Causes and 
treatment by Glycozone 29, 30 
Whooping-Cough-Causes and treat- 
ment 21, 22 
Women's weaknesses-Whites, Leu- 
corrhcea, etc.-Treatment 33, 34 
Yellow Fever-Marchand's Peroxide 
of Hydrogen (medicinal) is the only 
harmless antiseptic remedy to be 
applied 33, 
Copyright, 1890, by Charles Marchand. RELATIONS 
OF 
BACTERIA TO DISEASE. 
The branch of science named Bacteriology was opened to the 
medical profession by the classical researches of Prof. Pasteur in the 
settlement of the question of spontaneous generation, and in his sub- 
sequent studies of the process of fermentation. With the investigations 
of that distinguished French savant began our first positive knowledge 
of the definite relations of bacteria to disease in the animal kingdom. 
Prof. Robert Koch, of Berlin, has contributed widely by his experi- 
ments to the progress in knowledge of the etiology of infectious and 
contagious diseases. 
Owing to the methods which he has devised in order to practically 
and easily isolate different species of bacteria, we are now enabled to 
follow the phases of their development in pure cultures, under varying 
circumstances. 
Microscopical examinations show that, during the various stages of 
their life, bacteria present different forms and dimensions ; but it is also 
demonstrated that one species of bacteria, placed under the same circum- 
stances, always present the same forms, and produce the same effects. 
Bacteria are principally constituted by an albuminoid substance, 
called microproteine. 
The pathogenic bacteria only are of the greatest interest to the 
physician, and, according to the definition given by Prof. Koch, a micro- 
organism is pathogenic when it presents the following characteristics : 
First-It must be found in the excretions, secretions, or tissues of 
the animal suffering or dead from the disease. 
Second-The micro-organism must be cultivated out from the 
organism. 
Third-A pure culture inoculated in an animal should reproduce 
the disease. 2 
Fourth-The bacteria should be found in the humors or tissues of 
the animal after death. 
Pathogenic bacteria are differently affected in their infective power 
by the soil in which they grow ; some of them have a limited or local 
action, and others produce the infection of the whole system with a 
prodigious rapidity. 
These facts have been demonstrated from microscopical examina- 
tions ; for example, the autopsy shows that the blood of a patient who 
died from Diphtheria is invaded with a large number of microbes called 
micrococci, the same microbes being detected also in the diphtheritic 
membrane, which was at first the seat of this infectious disease. 
The microscopical examination of the blood of a patient who died 
from Anthrax shows the presence of the Bacillus Anthracis, which was 
at first found only in the excretions or pus coming from the infected 
surface. 
Consequently, the contagion is not always immediate. During this 
period of localization of the disease, the microbian element should be 
destroyed by a proper medication, in order to prevent its propagation 
through the whole system. 
Micro-organisms or germs in the atmosphere have been shown by 
Ehrenburg to exist in masses or clouds ; so that, in a room containing 
infection, a portion of the air may be loaded, while other portions are 
nearly free, which would seem to explain cases of escape from septic 
or zymotic influences. 
It is owing to the presence of these micro-organisms that Profs. Pas- 
teur, Koch, Tyndall, and others have been able to establish the germ 
theory of disease. 
Diseases caused by Germs or Microbes.-It is to the micro- 
organisms we are indebted for Catarrh, Ozoena, Hay Fever, Diphtheria, 
Croup, Sore Throat, Quinsy, Tonsilitis, Bronchitis, Whooping-cough, 
.Laryngitis, Pharyngitis, Pneumonia, Consumption, Catarrh of the 
Stomach, Women's Weaknesses, Whites, Leucorrhoea, Typhoid Fever, 
Scarlet Fever, Measles, Small-pbx, Skin Diseases, Yellow Fever, Chol- 
era, Abscesses, Carbuncle, Ulcers, Gonorrhoea, Syphilitic Sores, and 
other chronic affections. 
It is no wonder, after becoming acquainted with such facts as the 
above, that scientists have studied with such care the properties of 
antiseptics in order to destroy the germs. 3 
Destructive Action of Ozone upon the Virus.-A fact known 
by bacteriologists and chemists is that : All virus is albuminoid, 
whether propagative or not ; it is destroyed, or by coagulation rendered 
inert, by the oxidizing action of " Ozone," just as it is by contact with 
corrosive sublimate and other antiseptics. 
Then, it is evident that if some substance could be produced which 
would oxidize or destroy these micro-organisms, so as to change their 
infectious character, a great benefit would result, providing this de- 
stroyer of germs would have no injurious consequences upon the life of 
animals. 
Such a substance we have in ozone, Oq or condensed oxygen, O2 -j- O. 
It is nature's disinfectant. 
Houzeau found the air of the country at the height of six feet above 
the ground to contain u of its weight of ozone, or ?q-0]0 o o of its 
volume. 
This very small quantity of ozone is sufficient, owing to its wonder- 
ful oxidizing power, to destroy germs. 
" Ozone " is a normal constituent of fresh air ; its proportion varies 
with temperature and electric conditions of the atmosphere. 
Billard, Wolf, Boeckel, and Strambes agreed that the cholera, when 
it raged in Strasbourg, Berlin, and Milan, coincided with the absence of 
ozone in the atmosphere, and that ozone reappeared at the end of the 
epidemy. 
These observations are in perfect accord with those obtained by Dr, 
F. H. Hammond. Dr. Moffatt, Romain Vigouroux, Uhle, and numer- 
ous other scientists also attribute the prevalence at time of cholera, 
malarious fever, to the absence of ozone in the air. 
Is it due to an excessive production of miasms relatively to the 
normal proportion of ozone, or is it because " Ozone " is in deficiency 
to destroy these germs ? 
No one could answer this question, but the positive fact is that : 
" If Ozone is in excess, there is no epidemy." 
The wonderful antiseptic value of " Ozone " has attracted the atten- 
tion of all scientists, and a number of chemists have devised different 
methods of its production ; but no one of these processes could be 
used to manufacture ozone industrially. 
We have in Peroxide of Hydrogen, H202, a substance which is always 
on a strain to break up into water and nascent oxygen, or ozone. 4 
This fact, that Peroxide of Hydrogen generates " Ozone," is proved 
by experiments which I have made in order to establish the compara- 
tive chemical reactions between these two wonderful bactericides, and 
I now submit to the profession the results which I have obtained : 
COMPARATIVE CHEMICAL REACTIONS BETWEEN MARCHAND'S PEROXIDE 
OF HYDROGEN (MEDICINAL), H2O2, AND OZONE (FORMULA O3). 
H2 O2 Solution. 
Result 
of reaction : 
Potash and Iodine. 
Iodide of Potassium So- 
lution in presence of 
Result 
of reaction : 
Ozone. 
Potash and Iodine. 
Immediate decoloration. 
Escaping of Oxygen 
Gas and formation of 
brown Oxide of Man- 
ganese. 
Permanganate of Potash 
Purple Solution in pres- 
ence of 
H2 02 Acidulat- 
ed Solution. 
Result 
of reaction : 
Ozone. 
Mn2 Og Ra 4- 2 H2 O2 -2 KHO + Mn2 O4 H2 -f- 06 
Same reaction. 
Peroxide of Iron Salt So- 
lution and Ferricya- 
nide of Potassium So- 
lution mixed together 
in presence of 
H2 O2 Solution. 
Result 
of reaction : 
Ferricyanide is trans- 
formed into Ferrocya- 
nide of Potassium, giv- 
ing a blue coloration. 
Ozone. 
Result 
of reaction : 
Same result. 
Tincture of Indigo in 
presence of 
H2 O2 Solution. 
Result 
of reaction : 
Result 
of reaction : 
Decoloration. 
Ozone. 
Decoloration. 
Nitrous acid in presence 
of 
H2 O2 Solution. 
Result 
of reaction : 
Result 
of reaction : 
Formation of Nitric 
Acid. 
Same result. 
Ozone. 
Arsenious Acid in pres- 
ence of 
H2 O2 Solution. 
Result 
of reaction : 
Result 
of reaction : 
Formation of Arsenic 
Acid. 
Same result. 
Ozone. 
Tincture of Guaiacum 
mixed with either 
Blood or Extract of 
Malt. 
H2 O2 Solution. 
Result 
of reaction : 
Blue coloration, with ef- 
fervescence and coagu- 
lation of albumen. 
Ozone. 
Result 
of reaction : 
Same reaction. 
Organic substances such 
as Cotton, Woollen, 
Silk, Feathers, Hair, 
Bones, Ivory, etc., in 
presence of 
H2 O2 Alkaline 
Solution. 
Result 
of reaction : 
Oxidizing and Bleaching 
Action. 
Same result but slower 
action. 
Ozone. 5 
Immediate decomposi- 
tion of H2 O2 produc- 
ing nascent oxygen (or 
ozone); coagulation of 
albuminoid substances; 
destruction of pus and 
bacteria ; absolute dis- 
infection locally as well 
as in the surrounding 
atmosphere. Water and 
Oxygen Gas are the 
results of the above 
reaction. 
Organic substances in a 
decomposing state such 
as Meat, Fish, etc., 
mucous discharges, 
Bacteria, etc., in pres- 
ence of 
H2 O2 Solution. 
Ozone. 
Same result. Ozone trans- 
formed into Oxygen. 
Phosphorous Acid in 
presence of 
H2 O2 Solution. 
Ozone. 
Formation of Phosphoric 
Acid. 
Same result. 
H2 O2 Solution. 
Ozone. 
Formation of Sulphuric 
Acid. 
Sulphurous Acid in pres- 
ence of 
Same result. 
Effervescence, oxidation, 
and coagulation of the 
Albumen. 
Blood and Albumen in 
presence of 
H2 O2 Solution. 
Ozone. 
Same result. 
IMPORTANT INFORMATION ON PEROXIDE OF 
HYDROGEN. 
Pure anhydrous Peroxide of Hydrogen yields four hundred and 
seventy-five volumes of oxygen ; that is, it gives off four hundred and 
seventy-five times its own volume of oxygen. It is a very unstable 
liquid compound, having by itself a slight acid reaction to the litmus 
paper. Its decomposition into water and oxygen takes place under the 
most enigmatical influences. Hence it is not an article of commerce. 
Charles Marchand's Peroxide of Hydrogen (medicinal) is really a 3^ per 
cent, solution of the anhydrous peroxide in water ; 1 per cent, solution 
yields 4.75 times its own volume of oxygen. Consequently, the Per- 
oxide of Hydrogen (medicinal) which I manufacture yields " 3k times 
4.75 " its own volume of oxygen ; viz., a trifle more than fifteen times 
its own volume of oxygen gas. It is called a 15-volume solution. 6 
Owing to the unstableness of this compound, my medicinal prepara- 
tion is acidulated with of hydrochloric acid and yoVo °f phos- 
phoric acid. The acid is indispensable in order to preserve the solution 
from rapid decomposition, and it is unnecessary to neutralize these 
traces of acid, before use, even in the most delicate cases. 
All injurious chemicals are eliminated from Charles Marchand's 
Peroxide of Hydrogen (medicinal). It is a colorless, almost tasteless, 
and odorless liquid. Being kept in a cool place, such as a cool cellar 
or a refrigerator, it will not deteriorate, and will keep for any length 
of time. 
The fifteen volume solution of Peroxide of Hydrogen (medicinal) 
freezes at the temperature of io° to n° Fahr. ; in this event, thaw it 
out slowly at a temperature not exceeding 700 Fahr., and it will not 
lose any of its strength. 
Testing Process.-The following is the testing process which I 
recommend to the physician : 
The standardizing test solution is made by dissolving 3,704 grammes 
of permanganate of potash in distilled water, and making up the 
measure to 1,000 cubic centimetres. Each cubic centimetre of this 
solution corresponds to one volume of oxygen (formula O) when 
applied to one cubic centimetre of any solution of Peroxide of Hydro- 
gen. * 
The test is made by adding to about 50 or 60 cubic centimetres of 
water, acidulated with 2 cubic centimetres of pure sulphuric acid, a 
cubic centimetre of the peroxide of hydrogen solution to be tested. 
Into this, with constant stirring, is dropped, from a graduated burette, 
the permanganate solution until the color of the permanganate ceases 
to be discharged. 
Each cubic centimetre, and fraction of a cubic centimetre, required 
to reach this point, indicates one volume and fraction of a volume 
of oxygen that is available in the solution tested. 
Pure anhydrous peroxide of hydrogen, H2O2, being submitted to the 
above-mentioned test, shows that one cubic centimetre of it contains 
475 cubic centimetres of oxygen gas (formula O); but it would be 
erroneous to say that it contains 475 cubic centimetres of " Ozone " 
(formula Os), or condensed oxygen, O2 + O. 
* The reader will notice that I do not refer to "one volume " of ozone (formula O3), or condensed 
oxygen (Oa + O), but I say, positively, " one volume " of " oxygen " (formula O). 7 
The results of my experiments, published on page 4, prove that 
oxygen exists in peroxide of hydrogen in its allotropic state, called 
"ozone" or "condensed oxygen." 
Action of Charles Marchand's Peroxide of Hydrogen upon 
Infected Surfaces.-When Peroxide of Hydrogen (medicinal) is 
brought into contact with any diseased surface, either of the skin or of 
the mucous membranes, its decomposition takes place immediately, and 
at first " ozone," which is the result of this reaction, coagulates the albu- 
minoid matters of the secretions, the pus is destroyed, and also the 
bacteria. As soon as " ozone " has accomplished its cleansing effects 
upon the infected surface, it is readily transformed into ordinary 
oxygen, owing to its instability. 
It is of great importance to notice that water, charged with fifteen 
times its own volume of oxygen gas (formula O) under pressure, has 
no similar action whatever on the albuminoid substances, as there is no 
coagulation, and no cleansing effects upon the unhealthy secretions of 
the infected surfaces. 
This remark was necessary in order to establish plainly the differ- 
ence between the therapeutical value of Peroxide of Hydrogen and the 
Oxygen or the Compound Oxygen treatments.* 
Although Ch. Marchand's Peroxide of Hydrogen (medicinal) is rec- 
ognized by leading physicians (see the opinions of the medical profes 
* Concerning the so-called " Compound Oxygen treatment," I shall refer the profession to a 
very elaborate report on : 
"The Management of Pulmonary Diseases," by Karl von Ruck, B.S., M.D., Director of the 
Winyah Sanitarium for Diseases of the Throat and Lungs. Ashville, N. C., 1889. On pages 8 and 
9 of this publication, the author writes as follows : 
"Inhalation of Oxygen.-Undoubtedly some benefit has been derived from such inhalations in 
anaemia and digestive derangements, also in certain forms of dyspnoea I have seen patients made 
much more comfortable after each inhalation, especially when a small quantity of nitrous oxide 
was added. I have also seen an occasional but undoubted increase in the number of red 
blood-corpuscles under its administration, both in essential and symptomatic anaemia, especially 
when iron preparations, which alone had proved inefficacious, could be administered at the same 
time. Its range of usefulness in consumption is secondary altogether to many other means, and 
it is only occasionally that anything more than temporary relief can thereby be given, and, no 
matter how plausible the theory as to its influence upon nutrition, practical experience shows that 
its use is always experimental, and frequently without result, the same as is the case in its 
employment in other diseases. Its mixture with nitrous oxide, in the form of the so-called 
'compound oxygen,'by the temporary stimulating ci intoxicating effect of the laughing gas, 
has no advantage whatever, except in dyspnoea, but it makes the patients who become the 
victims of charlatans feel that ' something powerful ' is present in such inhalations, and induces 
them to believe in it the more readily. This 'compound oxygen cure for consumption' still 
flourishes in many localities, the same as do the quack remedies for the same object upon the 
shelves and counters of our druggists, and I have no doubt the venders of such, with their adver- 8 
sionon page 42) as being the most powerful and reliable antiseptic known, 
I now beg to submit to the profession the results of comparative tests 
which I have made, in order to demonstrate experimentally the differ- 
ence between the bactericide potency of the following chemicals, acting 
upon a diphtheritic membrane for the destruction of microbes present 
in half a gramme of the said membrane. 
Mixture or solution containing 3^ per cent, of the following 
chemicals : 
QUANTITY OF THE MIXTURE OR SOLUTION REQUIRED TO 
ANNIHILATE MICROBES. 
Cubic Centimetres. 
Glycozone (harmless) 0.75 
Biniodide of mercury 1.00 
Biniodide of silver '. 1.33 
Marchand's Peroxide of Hydrogen, medicinal (harmless) 2.00 
Bichloride of mercury 3.Q0 
Nitrate of silver 5.00 
Hypochlorite of lime 9.00 
Chlorine gas (aqueous solution) 10.00 
Iodine t 10.00 
Bromine 24.00 
Iodoform (when fresh) 28.00 
Salicylic acid 40.00 
Muriatic acid 100.00 
Carbolic acid 128.00 
Permanganate of potash . 140.00 
Chlorate of potash 158.00 
Alum 180.00 
Tannin 190.00 
Common salt 196 00 
Sulphide of calcium 201.00 
Boracic acid 300.00 
Sulphurous acid 325.00 
Lactic acid 360.00 
Chloride of iron 371-00 
Thymol, eucalyptus, bicarbonate of soda, lime-water, turpentine, 
have no action at all upon the microbes of a diphtheritic membrane 
tisements, are as injurious parasites upon the consumptives as are the tubercle bacilli themselves ; 
and while we must acknowledge that our efforts in phthiso-therapy against the latter have thus 
far been unavailing, many lives could undoubtedly be saved if the former could be extinguished by 
the enactment of wise laws which would oblige them to derive their means of livelihood otherwise 
than by trifling with human life." 9 
when they are developed ; but they may have, to a certain extent, a 
preventive action upon the development of the spores. 
The permanganate of potash, hypochlorite of lime, bichloride of 
mercury, the aqueous solution of chlorine gas, carbolic acid, nitrate of 
silver, etc., destroy the microbes ; but, being poisonous, they have the 
most dangerous effect upon the patient's life. 
It is worthy of note that the medicinal preparations made by 
Charles Marchand, viz., Glycozone and Peroxide of Hydrogen (medi- 
cinal), are absolutely harmless. All other chemicals have toxicant, cor- 
rosive, or poisonous properties, as is proved by chemical tests ; and 
their use is, in many instances, more dangerous than the disease itself. 
By referring to the comparative tests published on page 8, it is 
easy to notice that Charles Marchand's Peroxide of Hydrogen (medic- 
inal), as a bactericide, is i4 times as strong as bichloride of mer- 
cury, 2^ times as strong as nitrate of silver, 5 times as strong as 
iodine, 14 times as strong as iodoform, 20 times as strong as salicylic 
acid, 64 times as strong as carbolic acid.* 
* The Dangers of Carbolic Acid.-The following experiments which I have made prove beyond 
doubt the dangers of applying carbolic acid in the treatment of suppurative diseases. 
Six dogs were submitted to the action of this corrosive antiseptic in the following manner: 
Two to three square inches of hair on the leg of each animal upon which the experimentation 
took place was closely shaved. 
Morning and evening an application, from 8 to io drops (three per cent, solution) of carbolic 
acid was made upon these prepared surfaces and continued for ten days. 
One hour or so after each application the surface was dry, owing to the evaporation of water, 
and then, as an immediate consequence, it was covered by a small quantity of pure, concentrated 
carbolic acid, of which the corrosive properties are well known. 
At the expiration of said time two of these dogs were sick, each one having an ulcer on the 
prepared surface of the leg, which was due to the repeated application and evaporation of the 
three per cent, solution of carbolic acid ; and three days later each one of the four other dogs had 
an ulcer of the same nature, which was produced from the same cause. 
These four dogs were then submitted to treatment by my Peroxide of Hydrogen, which in four 
weeks thoroughly cured them. 
The application of the three per cent, solution of carbolic acid on the ulcers of the two other 
dogs was again continued, and on the fiftieth and sixty-second day, respectively, both animals 
expired from blood-poisoning. The autopsy showed that the blood of these animals was invaded 
by the bacteria of Davaine, which were detected by a microscopical examination. GENERAL DIRECTIONS FOR APPLYING 
CH. MARCHAND'S PEROXIDE OF HYDROGEN 
(MEDICINAL), HjO., 
IN THE TREATMENT OF DISEASES CAUSED BY GERMS. 
NOSE.-THROAT AND CHEST DISEASES.-TREATMENT. 
CA TARRH OR THE NOSE AND CA TARRH OF THE TH RO A T. 
Causes.-Micro-organisms, principally of the micrococcus species, 
have been detected by microscopical examinations, by scientific men, 
and by myself, in the mucous discharges from the nostrils of persons 
afflicted with this disease. Those germs which are the cause of the 
infection are readily destroyed by Charles Marchand's Peroxide of 
Hydrogen (medicinal), and there is no danger for the patient to use 
this remedy in any quantity, as it is positively harmless. 
Treatment.-By means of an atomizer, made of glass and hard 
rubber, spray the nose and the throat copiously and repeatedly twice 
or three times every day with a mixture of 
r tablespoonful Marchand's Peroxide of Hydrogen (medicinal), 
with 4 to io tablespoonfuls of water, 
according to the degree of inflammation in the mucous membranes of 
the nasal cavities ; and, in case of extreme sensitiveness, use even 
a still larger proportion of water. 
Note.-In the absence of an atomizer, apply the remedy to the nose by sniffing the 
liquid from the hand through the nostrils repeatedly, and gargle the throat. It is 
always beneficial to swallow some of the remedy. 
Do not blow the nose too hard, as it might cause a temporary bleed- 
ing. 
In chronic cases of long standing, especially at the beginning of the 
treatment, when the tenderness of the mucous membrane is excessive, 11 
it often happens that the patient will feel, during one hour or so after 
each application of the remedy, a partial obstruction of either one or 
the other of the nostrils. 
This very unpleasant feeling is often accompanied by frequent 
sneezing, which is due to the tickling sensation produced in the nasal 
cavities by the presence of a great quantity of minute bubbles of 
" Ozone," being set free from the decomposition of Charles Mar- 
chand's Peroxide of Hydrogen coming in contact with the infected 
surface. The unhealthy secretions are destroyed by " Ozone," and 
the cleansing of the nostrils is made perfect. 
In chronic cases, when the middle ear is affected, deafness is very 
often the consequence of this disease. Then ozonized vapor inhalations 
should follow immediately the spraying of the nose and the throat, and 
should be administered by means of Charles Marchand's Hand Atom- 
izer and Ozonizer, with a mixture thoroughly made of 
half Marchand's Peroxide of Hydrogen (medicinal) 
and half chemically pure glycerine. 
Renew this mixture every three days. It is important that the above 
mixture should be made perfect by shaking the bottle well, otherwise 
the spray-tube of the apparatus might be clogged on account of the 
syrupy nature of the glycerine.* 
The profession well know that the therapeutical agents used for the 
treatment of this disease have been as follows : 
Bichloride of Mercury.-Calomel.-Sulphate of Zinc.-Sulphate of Copper. 
-Alum.-Nitrate of Silver.-Carbolic Acid.-Salicylic Acid. -Permanganate 
of Potash.-Borax.-Boracic Acid.-Subnitrate of Bismuth.-Common 
Salt.-Muriate of Ammonia.-Extract of Eucalyptus.-Thymol.-Cocaine. 
-Camphor, etc. 
* When chronic Catarrh of the Nose is very tenacious and painful, it is necessary at night, before 
retiring, to apply a few drops of Glycozone to the nostrils. Sniff it hard, as it will accelerate the 
cure. 
In many cases the incurability of Chronic Catarrh of the Nose is due to partial or complete 
obstruction of the nasal cavities, caused by some abnormal conditions of growth, differing in their 
nature. 
When such is the case, apply Marchand's Peroxide of Hydrogen, as heretofore explained, morn- 
ing and evening, and after ten or fifteen days, if the excrescence does not disappear, it will be 
necessary to have a surgical operation performed for its removal. 
A permanent cure may then be effected in a very short time. 
After the excrescence has been removed or destroyed by means of the thermo-cautery, or any 
other operation (no caustic should be used, as it will most likely destroy both taste and smelly an 
absolute cure is certain if the Marchand Peroxide of Hydrogen treatment is earnestly followed. 12 
It is easy to understand why Marchand's Peroxide of Hydrogen 
(medicinal) will surely accomplish a permanent cure, while the above- 
mentioned bactericides can give only temporary relief, and they are 
apt to injure or destroy both taste and smell. 
First-Because Marchand's Peroxide of Hydrogen is the most 
powerful of all antiseptics yet discovered. (See page 8, " Comparative 
Tests.") 
Second-Marchand's Peroxide of Hydrogen (medicinal) is absolutely 
harmless when applied externally or administered internally. 
Third-The borax, boracic acid, subnitrate of bismuth, muriate of 
ammonia, common salt, camphor, eucalyptus, thymol, are not very 
dangerous remedies, but their bactericide properties are too limited to 
destroy the germs which are the cause of the disease. 
On the contrary, Marchand's Peroxide of Hydrogen annihilates these 
germs instantaneously, and it leaves the healthy surrounding tissues in 
their normal condition. 
OZOENA, OR PUTRID CATARRH OF THE NOSE. 
In case of Ozoena, Marchand's Peroxide of Hydrogen (medicinal) 
should be applied three times daily, diluted in the following proportion : 
Mix i tablespoonful Marchand's Peroxide of Hydrogen 
with 4 to 7 tablespoonfuls of water. 
It is only in case of extreme tenderness of the mucous membrane 
that a weaker solution should be used, as follows : Mix i tablespoonful 
of Marchand's Peroxide of Hydrogen with 7 to 10 tablespoonfuls of 
water. 
Spray the nostrils and the throat successively and copiously with this 
diluted Marchand's Peroxide of Hydrogen, or, in the absence of an 
atomizer, apply the remedy to the nose by sniffing the liquid from the 
hand through the nostrils repeatedly, and gargle the throat. 
This treatment is so powerful that the destruction of the microbian 
element takes place immediately, and the putridity which characterizes 
this peculiar and repulsive affection is arrested three or four days after 
the beginning of its application. 
The cure is ordinarily accomplished in four weeks, but in some 
instances, when the case is of a very long standing-having become 
chronic-it requires a longer time to effect an absolute cure. 13 
In case of sneezing and obstruction of the nostrils after each appli- 
cation of the remedy, see the explanations given, page io, article 
headed " Catarrh of the Nose." * 
Marchand's Peroxide of Hydrogen (medicinal) is the most powerful 
remedy which can be used in order to subdue this most offensive and 
very repulsive disease, and it has no injurious or poisonous conse- 
quences. 
HAY FEVER.-ROSE COLD.-CORYZA. 
Causes.-The microscopical examination of the unhealthy mucous 
secretions and excretions from the nostrils of Hay-fever sufferers 
demonstrated the presence of small ovoid micro-organisms, which are 
annihilated instantly when brought into contact with Marchand's Per- 
oxide of Hydrogen (medicinal). 
It is worthy of notice that the degree of susceptibility to the infectious 
action of these germs or microbes differs with different people. The 
spores and germs which cause this disease do not always find a proper 
medium for development in the mucous secretions of different people. 
The peculiarity of this disease is that any one who is afflicted with 
Hay Fever can foretell every year, almost to a certainty, the day upon 
which the disease will begin, and also the day upon which they will get 
rid of it. 
The logical explanation of this is that the conditions of life of 
afflicted people are always the same ; that is, " the circumstances and 
surroundings of their existence are absolutely alike from year to year." 
Thus the microbian causes of the trouble develop under the same in- 
fluences every year, at about the same time ; and, consequently, the 
disease begins when the atmospheric conditions become favorable for 
the development of the spores I have mentioned. These spores grow, 
under proper conditions of temperature and dampness, in the mucous 
secretions of the nostrils, the microbian affection takes place, and in- 
flammation and ulceration of the mucous membrane is the consequence. 
These micro-organisms continue their growth as long as these favor- 
able atmospheric conditions exist, and they disappear as soon as the 
temperature falls and while it remains at a lower degree. Then the 
effects disappear with their causes, and the patient gets rid of his trouble. 
* Glycozone should be applied to the nostrils morning and evening, in order to accelerate the 
cure. 14 
Treatment.-The causes of Hay Fever being now well established, 
it is easy to understand that any remedy having the property to destroy 
microbes or germs will surely prevent or cure the disease by removing 
the cause, providing this antiseptic remedy will have no injurious 
effects upon the surrounding healthy tissues. 
In case of Hay Fever, the remedy should be applied locally to the 
nostrils as a spray, and also by inhalations, in order to subdue the 
asthmatic attacks which accompany this very troublesome complaint. 
It has been demonstrated that among the list of antiseptic remedies 
published on page 8, Marchand's Peroxide of Hydrogen (medicinal) is 
the most powerful bactericide, and it is absolutely harmless. 
I have explained on page 7 that : When Marchand's Peroxide of 
Hydrogen (medicinal) comes in contact with any open and infected 
surface, either of the skin or the mucous membrane, ozone is set free, 
the microbes are instantly destroyed, as well as the unhealthy secretions 
which are caused by their action, and then the diseased surface is 
thoroughly disinfected and made perfectly clean and healthy. The 
residue of this reaction is water and a small quantity of coagulated 
albumen. 
In fact, this Marchand's Peroxide of Hydrogen treatment is based 
upon the indisputable results which are obtained when a Hay-fever 
patient is going to the White Mountains, where the atmospheric con- 
ditions are such that the air contains always a small quantity of ozone. 
The constant breathing of this ozonized air accomplishes the cure of 
this disease in a very short time. 
Hay Fever will always be prevented by an early application of Mar- 
chand's Peroxide of Hydrogen (medicinal), in those cases which occur 
regularly at known periods of the summer. When the disease has 
developed, the same treatment will check it within three or four days, 
and the.cure is effected in less than two weeks ; but it is advisable to 
continue the treatment during the whole Hay-fever season. 
The remedy should be applied as follows : 
First-Spray the nostrils and the throat copiously and repeatedly 
twice or three times every day with a mixture of 
1 tablespoonful of Marchand's Peroxide of Hydrogen (medicinal) 
with 3 to 8 tablespoonfuls of water, 
according to the degree of inflammation. 15 
Second-By means of Charles Marchand's Hand Atomizer and 
Ozonizer, an inhalation of ozonized vapor should be administered with 
a mixture thoroughly made of 
half Marchand's Peroxide of Hydrogen (medicinal), 
half chemically pure glycerine. 
The above should be carefully mixed and renewed every three 
days. 
(See description and cuts of Charles Marchand's Hand Atomizer 
and Ozonizer, pages 16-17.) 
The duration of each inhalation should not exceed ten minutes, and 
should be taken three to six times daily. Inspirations should be as 
deep and prolonged as possible.* 
The above described treatment in cases of Hay Fever is unequalled 
as a preventive, and it is the only cure for this periodic, repulsive, and 
very troublesome disease. 
In case of obstruction of the nostrils or sneezing after each applica- 
tion of the remedy, see the explanations given on page 10, article 
headed 11 Catarrh of the Nose." 
* In very severe cases an application of Glycozone to each nostril, morning and evening, will 
accelerate the cure. (See page io, article headed " Catarrh of the Nose.") 
The ozonized vapor inhalations constitute a very important part of the treatment for this 
disease, as it relieves immediately Asthma, which always accompanies Hay Fever. 16 
CHARI.ES MARCHAND'S 
COMBINED 
HAND ATOMIZER AND OZONIZER. 
DESCRIPTION : 
Cut No. i.-This cut represents apparatus when unpacked from its original box. 
Cut No. 2.-This cut represents apparatus ready for inhaling vapor through the nose 
in the treatment of Asthma, Bronchitis, and all lung diseases. 17 
Cut No. 3.-This cut represents apparatus ready for inhaling vapor through the 
mouth in the treatment of Asthma, Bronchitis, and all lung diseases. 
Cut No. 4 -This cut represents apparatus ready for spraying the throat. 18 
Cut No. 5.-This cut represents apparatus ready for spraying the nostrils. 
Each separate part of the apparatus 
is designated by the following letters : 
A.-The vaporizing glass bulb, with its 
two openings, B and C. 
D.-The curved spray-tube (hard rubber). 
E.-The bent glass tube. 
F.-The slightly curved glass tube. 
G.-The straight tip (hard rubber). 
H.-The nasal tip (hard rubber). 
I. J.-The two soft rubber bulbs. 
K.-The soft rubber stopper. 
L.-The glass bottle containing the remedy. 
Cut No. 6.-This cut shows the different parts of the Hand Atomizer and Ozonizer 
when disconnected. 19 
The three-ounce glass bottle L is graduated in twelve parts, each 
part corresponding to one-quarter of one ounce, so that it is very easy 
to mix the medicine in the required proportions. 
The working of this apparatus will be easily understood by referring 
to the above illustrations. 
DIRECTIONS FOR USING THE APPARATUS IN THE 
DIFFERENT CASES. 
First-The proper mixture of Marchand's Peroxide of Hydrogen 
(medicinal) with chemically pure glycerine for administering ozonized 
vapor inhalations is thoroughly made in the bottle Z, as it is shown on 
cuts No. 2 and No. 3. 
Then, by quickly and repeatedly pressing the terminal soft rubber 
bulb Z, the air is forced through the bottle Z, and produces a coarse 
spray in the vaporizing bulb A. The concussion of the spray against 
the glass breaks up the mixture, and a large amount of fine ozonized 
vapor escapes in a continuous flow through the bent glass tube E, as 
represented on cut No. 2, or through the straight glass tube F, as 
shown on cut No. 3. 
When the condensed liquid in the bulb A reaches the lower part of 
the neck E, it should be emptied in the bottle Z, by disconnecting 
the spray-tube D. Then reconnect the parts, and the apparatus is 
again ready for use. 
Second-When the apparatus is needed to spray either the throat or 
the nose, Marchand's Peroxide of Hydrogen (medicinal) is mixed with the 
necessary quantity of water in the graduated bottle Z, as shown on cuts 
No. 4 and No. 5. Note.-Some practitioners believe that Peroxide 
of Hydrogen may be inhaled by means of any of the ordinary inhalers, 
the same being placed in a jacket vessel of water heated to i2o°-i4c° 
Fahr. This method is absolutely wrong, for the following reason : 
When Peroxide of Hydrogen is heated to i2o°-i4o° Fahr., steam, 
oxygen (formula O), and only traces of ozone are inhaled by the 
patient (see foot note, page 7, article headed "Oxygen Inhalation "). 
On the contrary, when Peroxide of Hydrogen (medicinal) vapor is 
mechanically produced by means of the Hand Atomizer and Ozonizer, 
the vapor which reaches the diseased tissues has the same curative 
properties as Peroxide of Hydrogen itself. 20 
CAUTION. 
The spray-tube should be kept clean bypassing tepid water through it at 
least twice a week. Should it get clogged, disconnect the vaporizing 
bulb A and the bottle Z, unscrew the tip G, and blow both ways through 
the spray-tube, or pass a thin wire through it, as you would do for any 
ordinary spray atomizer. 
The above-described apparatus is entirely made of glass and hard rubber, 
because no metal should come in contact with Marchand's Peroxide of 
Hydrogen (medicinal). Use only silver, hard rubber, glass, or porcelain 
spoons to measure either Marchand's Peroxide of Hydrogen (medicinal) 
or Glycozone. 
Treatment of Asthma.-By means of Ch. Marchand's Hand 
Atomizer and Ozonizer, inhalations of ozonized vapor should be admin- 
istered three to six times daily. Any similar apparatus made of metal 
should never be used in connection with Marchand's Peroxide of 
Hydrogen (medicinal). 
The action of vaporized Marchand's Peroxide of Hydrogen (medic- 
inal), or ozonized vapor, upon the diseased surface of the bronchial 
tubes or the cells of the lungs is similar to the action of this bactericide 
upon any open sore or ulcer which is invaded by microbes. The 
microbian element is destroyed at the contact of ozone, which is set 
free, and the diseased tissues are purified and made healthy. 
The mixture for inhalations which has given the most satisfactory 
results is made of f 
one-half Marchand's Peroxide of Hydrogen (medicinal), 
mixed with one-half chemically pure glycerine. 
Mix well together by shaking the bottle, and renew this mixture 
every two days. 
The duration of each inhalation should not exceed ten minutes, and 
after each inhalation, during the winter, the patient should remain 
in-doors for fifteen or twenty minutes. 
In many cases of long standing it will be found very beneficial to the 
patient to take internally every day two or three tumblerfuls of ozon- 
ized water made of 
i ounce Marchand's Peroxide of Hydrogen (medicinal) 
with 2 pints of water. 
This will cleanse and purify the stomach and regulate the bowels. 
Bronchitis-Treatment.-By means of Charles Marchand's Hand 21 
Atomizer and Ozonizer three inhalations of ozonized vapor should be 
administered daily. 
It is the most efficacious local treatment which can be prescribed to 
subdue this disease, on account of the harmless, although very power- 
ful, antiseptic and healing properties of Marchand's Peroxide of 
Hydrogen (medicinal). 
It quickly checks profuse bronchial secretion, and by its stimulating 
action upon the diseased tissues of the bronchial tubes an absolute 
cure is effected in a very short time. 
Mixture for inhalations : 
One-half Marchand's Peroxide of Hydrogen (medicinal) 
with one-half chemically pure glycerine. 
This mixture should be made perfect by shaking the bottle, and 
renewed every three days. 
And as a beverage, drink daily three or four tumblerfuls of ozonized 
water made of 
i ounce Marchand's Peroxide of Hydrogen (medicinal) 
mixed with 2 pints of water. 
This beverage will have the most beneficial effect upon the stomach, 
which is always more or less affected by droppings from the throat. 
In this malady Marchand's Peroxide of Hydrogen (medicinal) 
destroys the microbes or germs which are the cause of the disease, 
the unhealthy secretions of the bronchial tubes disappear, and the 
diseased tissues are made healthy. 
Whooping-cough-Causes.-Dr. Burger, of Bonn, Germany, 
and Dr. Affanassieff, of Russia, have demonstrated the presence of 
micro-organisms in Whooping-cough sputum. Dr. Affanassieff has 
prepared, with all the precautions, for microscopical experimentation, 
a small portion of the expectoration of a Whooping-cough patient, 
which showed large numbers of short rod bacteria, part singly, partly 
in two and of larger chains. 
With pure cultures of these rod bacteria the investigator has made 
several experimental inoculations upon animals. A solution of this 
culture upon agar-agar, at least eight days old, in one-half a cubic 
centimetre of common salt, was made and injected into the windpipe 
or lungs of dogs and rabbits, of course under antiseptic precautions. 22 
The animals all contracted a disease similar to Whooping-cough, 
often complicated with Broncho-pneumonia. 
Several died, and the autopsy showed that the mucous membranes 
of the bronchi, of the trachea, and even of the nose, are the chief seats 
of the injected bacteria. 
This same bacterium was found in the lungs and respiratory mucous 
membranes of children who died of Whooping-cough. 
Dr. Affanassieff considers it to be the true cause of Whooping- 
cough, and names it the 11 bacillus tussis convulsive^." 
Dr. Schwenker (London Lancet, January 7, 1888) and Dr. Wenat 
(Medical News, June 2, 1888) have confirmed Dr. Affanassieff's obser- 
vations. 
One hundred cubic centimetres of the pure culture, containing a 
considerable quantity of the above-mentioned micro-organisms, have 
been submitted to the action of three cubic centimetres of Marchand's 
Peroxide of Hydrogen (medicinal). The complete annihilation of the 
bacteria has been effected in less than seventy seconds of contact. 
Treatment.-Whooping-cough, being caused by a microbian affec- 
tion, requires antiseptic treatment ; and Marchand's Peroxide of Hy- 
drogen (medicinal), applied in the following manner,will effect promptly 
an absolute cure : 
First-Spray frequently and copiously the nose, throat, pharynx, and 
larynx with a mixture made of 
r tablespoonful of Marchand's Peroxide of Hydrogen (medicinal) 
with 4 to 6 tablespoonfuls of water. 
The patient may swallow some of the remedy without discomfort, as 
it is beneficial and perfectly harmless. Three to four applications 
every day will be sufficient in most cases. 
Second-By means of the Hand Atomizer and Ozonizer, administer 
ozonized vapor three to six times daily, in order to insure the complete 
destruction of the microbian element in the respiratory organs. 
The mixture for inhalations should be made of 
half Marchand's Peroxide of Hydrogen (medicinal) 
with half chemically pure glycerine. 
Mix well together, and renew the mixture every three days.* 
* The disorders of the stomach which often accompany this disease will always be surely pre- 
vented and cured by the use of Glycozone as an internal treatment. Dose : i teaspoonful of Gly- 
cozone, diluted in a wineglassful of water, three times daily. 23 
Consumption, Phthisis, Tuberculosis of the Lungs- 
Causes.-It is a well-demonstrated fact that Consumption or Phthisis 
is caused by a microbe of a particular species which has been discov- 
ered by Dr. Koch, of Berlin, and which is called the Bacillus Tuber- 
culosis of Koch. 
Bacillus Tuberculosis 
in Sputum x 1250 diameters. 
With pure cultures of this bacillus, Dr. Koch and other scientific 
authorities have made experimental inoculations upon animals. A 
solution of this culture upon agar-agar was made and injected into the 
windpipe or lungs of dogs. The animals all contracted the Tubercu- 
losis of the Lungs or Consumption. This bacillus is located in tuber- 
cules, and it causes the formation of ulcerated cavities of the lungs. 
The bacillus tuberculosis is readily destroyed by antiseptic remedies; 
but although the annihilation of the microbian element is accomplished 
almost instantaneously by the action of Marchand's Peroxide of 
Hydrogen (medicinal), this remedy will not cure Consumption when 
the disease has reached such a degree of development that the lung 
tissue has broken down. In fact, if it should be possible to bring this 
remedy into contact with all parts of the lungs which are invaded by 
the bacillus, undoubtedly the cure of Consumption might be always 
effected by the ozonized vapor inhalations.* 
Treatment.-Frequent and deep ozonized vapor inhalations should 
be administered three to six times daily, with a mixture of 
2 to 3 tablespoonfuls of Marchand's Peroxide of Hydrogen (medicinal) 
with i tablespoonful of chemically pure glycerine well shaken. 
Renew this mixture every three days. 
* Whenever ozonized vapor is mentioned, it means " vapor produced by the Ozonizer from the 
mixture of Marchand's Peroxide of Hydrogen (medicinal) with chemically pure glycerine." 24 
The duration of each inhalation should not exceed ten minutes, and 
inspiration should be as deep and as prolonged as possible. The 
remedy will reach the lungs if administered either through the nose or 
mouth, by means of Charles Marchand's Hand Atomizer and Ozonizer. 
(See page 16.) 
Remain in-doors for fifteen to twenty minutes after each inhalation 
during the cold weather. 
It is easy to understand that, the ozonized vapor coming into con- 
tact with the bacillus tuberculosis, located in the ulcerated cavities of 
the lungs, " ozone," which is set free, destroys the microbian element 
immediately, as explained before on page 7. . 
When Consumption has not taken developments beyond its first or 
second stages-that is, when the ulcerated cavities caused by the bacil- 
lus tuberculosis are limited and can be easily reached by the ozonized 
vapor-the above treatment prevents absolutely the spreading of the 
infection and a cure is effected. But in all cases of Consumption, no 
matter at what stage of the disease, the relief of the patient will be 
surely and quickly obtained by the Marchand Peroxide of Hydrogen 
treatment. 
Ozonized vapor has no corrosive, toxic, or injurious action upon the 
healthy tissues of the lungs ; on the contrary, it has very powerful 
stimulating properties. In addition to the inhalations, the administra- 
tion of three tumblerfuls daily of ozonized water, made of 
11 ounces of Marchand's Peroxide of Hydrogen (medicinal) 
with 2 pints of water, 
after each meal, will be found very helpful to the relief of the patient. 
Sore Throat, Angina, Quinsy, Tonsilitis, and all Inflam- 
matory Diseases of the Throat. 
Treatment.-Spray or gargle the throat copiously and frequently 
with a mixture of 
1 tablespoonful of Marchand's Peroxide of Hydrogen (medicinal) 
with 3 to 6 tablespoonfuls of water. 
You may swallow the remedy without discomfort, as it is rather bene- 
ficial. In case of Tonsillar Abscesses gargle more frequently (every 
two hours, for instance), in order to destroy surely and quickly the pus 
which is present. 25 
Laryngitis.-Marchand's Peroxide of Hydrogen (medicinal) is cer- 
tainly the safest remedy to apply in order to subdue this disease. 
Spray or gargle three times every day with a mixture made of 
i tablespoonful Marchand's Peroxide of Hydrogen (medicinal) 
with 2 to 6 tablespoonfuls of water, 
and swallow a portion of the remedy. 
In many cases, ozonized vapor inhalations will accelerate the cure. 
Pharyngitis.-Spray or irrigate copiously the pharynx three times 
every day with a mixture of 
i tablespoonful Marchand's Peroxide of Hydrogen (medicinal) 
with 3 to 7 tablespoonfuls of water ; 
swallow a portion of the remedy, and administer ozonized vapor inhala- 
tions morning and evening. 
Appropriate internal medication may accelerate the cure. 
Croup, Membraneous Croup.-This disease seems to be caused 
by the same specific virus as Diphtheria, but it shows a milder grade of 
infection. 
When fully developed, whitish spots or membraneous exudations are 
observed in the larynx. After the membrane is once formed, if left 
alone it may be cast off in the form of a cylinder, in bands or shreds. 
Some recent experiments have proved that Marchand's Peroxide of 
Hydrogen (medicinal) destroys these membranes after a short contact, 
and by its curative properties the diseased surface is rendered healthy. 
In case of Membraneous Croup, the nose, throat, mouth, pharynx, 
and larynx should be flooded every two hours with a mixture of 
i tablespoonful of Marchand's Peroxide of Hydrogen (medicinal) 
with 4 to 6 tablespoonfuls of water. 
The membranes are destroyed, and by using this remedy frequently 
and very freely you prevent their reproduction. 
In this way the physician will observe that the inflamed parts are 
thoroughly and quickly cured, and there is no danger of the patient 
being exposed to the suffocation resulting from the development of 
these infected membranes.* 
* As an internal treatment, i tablespoonful of Glycozone diluted in a wineglassful of water and 
taken three times a day will prevent any disturbance of the stomach and regulate the bowels. 26 
Diphtheria-Causes.-Diphtheria is at first a local disease (see 
page 2), which is secondarily propagated to the general organism by 
a contagious virus located about the tonsils ; this virus is an albuminoid 
substance invaded by a large number of bacteria called micrococci. 
Marchand's Peroxide of Hydrogen (medicinal) destroys this virus 
instantaneously, and it has no injurious effects upon the surrounding 
healthy tissues. 
These cuts illustrate a well-developed case of Diphtheria before and 
after its cure by use of Marchand's Peroxide of Hydrogen (medicinal). 
Time taken to destroy the micrococci was less than 70 seconds. 
Magnified Diphtheritic Membrane, 8oo 
Diameters. Figure i shows the bacteria 
called micrococci. Fig. 2 shows the fibrin. 
Showing the same membrane after short 
contact with Peroxide of Hydrogen. The 
bacteria are destroyed ; the fibrin remains 
normal. 
Directions for Use.-Spray or gargle copiously, every two hours, 
the nose, throat, mouth, pharynx, and larynx with a mixture of 
i tablespoonful Marchand's Peroxide of Hydrogen (medicinal) 
with 4 to 6 tablespoonfuls of water. 
It is beneficial to swallow the remedy, ora portion of it, in gargling. 
The virus or germs are readily destroyed from the contact with 
Peroxide of Hydrogen (medicinal), and the contagion is therefore pre- 
vented. 
When Diphtheria is well developed it is necessary to spray the child's 
nostrils, throat, mouth, pharynx, and larynx more frequently with a 
mixture made of 
i tablespoonful Marchand's Peroxide of Hydrogen (medicinal) 
with 3 tablespoonfuls of water. 27 
It is only when the disease is spreading very rapidly that a more 
concentrated solution should be used, as follows : 
1 tablespoonful Marchand's Peroxide of Hydrogen (medicinal) 
with 1 to 3 tablespoonfuls of water. 
A child's nostrils, pharynx, and mouth may be flooded every three 
hours, or oftener, from a proper spray apparatus entirely made of hard 
rubber and glass, with diluted Marchand's Peroxide of Hydrogen 
(medicinal), without force and with very little discomfort ; and any 
solution which finds its way into the larynx or stomach is beneficial 
rather than harmful. 
Adults and children old enough to gargle the pharynx and rinse the 
mouth will get a better effect in this way* 
Dyspepsia-Predisposing Causes.-Deficient gastric secretion, 
with resulting fermentation of food, is perhaps the most prevalent 
cause of Dyspepsia. 
The two main constituents of gastric juice, namely, acid and pepsin, 
may be deficient in quantity or disturbed in their relative proportions. 
A certain amount of acid is absolutely essential to the digestive process, 
while a small amount of pepsin may be sufficient to digest a large 
amount of albuminoid food. 
Bidder and Schmidt have made repeated analyses of pure gastric 
juice, and their results are confirmed by the analyses of five specimens 
of gastric juice, free from saliva, and taken by Charles Marchand from 
dogs. 
The gastric juice of a dog is composed of : 
Water 968.20 
Pepton and pepsin 17.12 
Free muriatic acid 2.98 
Alkaline chlorides 4.16 
Ammonium chloride 0.51 
Chlorine 5.16 
Phosphates 
Lime 1.54 
Magnesia 0.28 
Iron 0.05 
The most careful analysis proved beyond doubt that fresh gastric 
juice contains only one mineral acid-that is, muriatic acid. 
* As an internal treatment, i teaspoonful of Glycozone diluted in a wineglassful of water, ad- 
ministered every three to four hours will prevent the microbian infection developing in the 
stomach of the patient, and that is a very important result to obtain in order to avoid the infection 
of the system. 28 
Exciting Causes.-The profession well know that excess in eat- 
ing and drinking, imperfect mastication and insalivation, the use of 
indigestible and unwholesome food and of alcohol, the imperfect 
arrangement of meals, over-drugging, etc., are chiefly the exciting 
causes of Dyspepsia, and indigestion is the immediate consequence. 
Constipation of the bowels is an almost universal accompaniment of 
deranged digestion, and when persistent for years it is apt to lead to 
the most disastrous consequences. 
The most prominent of the local symptoms of Dyspepsia are : A sense 
of fulness and distention after eating, discomfort during digestion, 
lack of appetite and eructations, or heart-burn, flatulence, regurgitations 
of food, and sometimes, in acute cases, nausea and vomiting. 
Now that I have resumed the causes of Dyspepsia, which produce 
a general inflammation of the coats of the stomach, the profession 
know that the innumerable remedies which have been recommended to 
subdue this disease may be classified as follows : 
First-Remedies having a stimulating action upon the secretion and 
muscular coats of the stomach. 
Second-Introduction in the stomach of a necessary amount of one 
or several of the constituent elements of the gastric juice, in order to 
make it normal. 
Third-Remedies having the property to lessen the abnormal irri- 
tability. 
Fourth-Remedies having the property to facilitate digestion. 
It is evident that any remedy which will restore the coats of the 
stomach to their normal condition will contribute to effect an absolute 
cure, providing the patient will observe a proper regimen. 
Glycozone, by its wonderful antiseptic and healing properties, not 
only prevents the fermentation of the food in the stomach, but it cures 
also the inflammation or irritation of the mucous membrane in a very 
short time. Consequently, the most powerful and efficacious treatment 
to be applied, in order to remove the causes of Dyspepsia, can be for- 
mulated as follows : 
Before or after each meal administer i teaspoonful of Glycozone in 
a wineglass nearly filled with water, stirred and taken three or four 
times daily. 
Use no other remedy. 
The digestion is accomplished, from the beginning of its application^ 29 
without the least discomfort. The relief is almost immediate, and a 
cure absolute, if earnestly used. 
After a few days the secretion of gastric juice is made normal, and 
the most acute cases of Dyspepsia, those of long standing, are perma- 
nently cured within two to six months of this treatment, when all other 
remedies have failed. 
Catarrh of the Stomach, or Gastritis, Chronic or Recent.- 
The mucous membrane of the stomach is usually the seat of this 
disease. 
Among the direct exciting causes of gastric inflammation, corrosive 
poisons and the excessive use of alcohol are recognized to be more 
prevalent than any others. 
Chronic Catarrh of the Nose is often the cause of Gastritis on 
account of the large quantity of infected secretions which, after de- 
veloping in the nasal cavities, find their way into the stomach. 
The immediate consequence of that dropping is to produce an 
inflammation of the coats of the stomach, and little by little the 
microbian infection produces a general morbid condition having the 
symptoms of Catarrh of the Stomach. 
In cases of acute Catarrh of the Stomach the autopsy shows that 
the mucous membrane is covered with a thick, tenacious, stringy 
mucus ; the secretion of gastric juice is very imperfect, and the diges- 
tion of food cannot be accomplished. 
Glycozone, by destroying the morbid element which is the cause 
of this disease, rapidly subdues the inflammatory condition of the 
coats of the stomach, and then the mucous membrane, being restored 
to its normal state, the secretion of the gastric juice will become 
regular, and the digestion will not be disturbed any more. 
Treatment.-Administer, three or four times daily, before or after 
each meal, 
i to 2 teaspoonfuls of Glycozone, 
diluted in a wineglassful of water, well stirred. 
This treatment will never fail to accomplish an absolute cure within 
two to six months, providing the physician will impress upon the mind 
of his patient that he should take his meals regularly and with sobriety. 
Ulcer of the Stomach.-This disease is due to various causes, 
of which the immediate effect is to interfere with the digestion. 30 
Vomiting of food is an indication of Gastric Ulcer, and in severe 
cases it is followed by hemorrhage. 
The gastric juice is secreted with deficiency, and in order to remove 
the cause of this disorder a powerful antiseptic treatment is required. 
The most satisfactory results are obtained : 
First-If the patient use as a beverage a small quantity of ozonized 
water at each drink, this ozonized water being made of 
i ounce of Marchand's Peroxide of Hydrogen (medicinal) 
with 2 pints of water. 
The microbian element is readily destroyed by the small quantity of 
ozone which is set free at the immediate contact of the ulcerated 
surface. 
Second-The healing part of the treatment consists in the adminis- 
tration of 
i to 2 teaspoonfuls of Glycozone 
diluted in a wineglassful of water, three or four times daily, before or 
after eating. 
This treatment is absolutely harmless, and the relief of the patient 
is obtained almost immediately. 
An absolute cure is effected within two to six months. 
Scarlet Fever-Causes.-It is a proven fact that this disease is 
caused by bacteria of the micrococcus species, as shown by the cut 
below, which illustrates a magnified portion of excretions of an ulcer 
of the larynx (8oo diameters) taken from a Scarlet-fever patient. 
Fig. i shows the bacteria of 
the scarlet fever. 
Fig. 2 shows the fibres of the 
tissue and globules. 31 
Every physician knows that Scarlet Fever is a contagious affection 
to the highest degree, and that it may be communicated by anything 
that has touched the patient, such as air, food, clothing, sheets, furni- 
ture, curtains, etc. All discharges from bowels, kidneys, nose, mouth, 
eyes, ears, and skin are dangerous ; and the poison may remain active 
for months or years by means of clothing packed away in drawers. 
Treatment.-The germs which cause this disease are readily 
destroyed by Marchand's Peroxide of Hydrogen (medicinal); and the 
most powerful local medication is obtained in the following manner : 
Spray or gargle the throat copiously and repeatedly every 2 to 3, 
hours with a mixture made of 
1 tablespoonful Marchand's Peroxide of Hydrogen (medicinal) 
with 3 to 5 tablespoonfuls of water.* 
As a preventive treatment for secondary infection : On the third day 
of Scarlatina Fever, the whole body of the patient should be washed, 
morning and evening, with equal parts of 
Marchand's Peroxide of Hydrogen (medicinal) 
and tepid water. 
Use a porcelain dish and a clean soft sponge. 
This local treatment does not preclude the internal medication, 
which may be deemed necessary by the attending physician. 
Typhoid Fever-Causes and Treatment.-It is a well-known 
fact that contaminated water is the cause of this disease. 
The following cut illustrates the typhoid bacille, magnified 1250 
diameters, from pure culture : 
* As a beverage, Glycozone should be administered three times daily. Dose-i teaspoonful 
diluted in a wineglassful of water. 32 
Marchand's Peroxide of Hydrogen (medicinal) destroys those 
microbes instantaneously. Consequently, a beverage made of 
i ounce Marchand's Peroxide of Hydrogen (medicinal) 
with 3 pints of water 
constitutes the most efficacious and powerful antiseptic treatment, 
which always prevents both pyaemia and septicaemia.* 
This antiseptic medication does not preclude the general treatment 
which may be prescribed by the attending physician. 
Anthrax-Carbuncle.-This affection, which is caused by the 
Bacillus Anthracis, is at first a local disease which requires a very 
powerful antiseptic treatment, immediately after the carbuncle has 
been opened by a surgical operation or otherwise. 
The following cut illustrates the Bacillus Anthracis, magnified 1250 
diameters, from pure culture : 
Bacillus Anthracis x 1250 
diameters. 
The Bacillus Anthracis is readily destroyed by Marchand's Peroxide 
of Hydrogen (medicinal). 
Treatment.-Wash or irrigate the sore, morning and evening, with 
Marchand's Peroxide of Hydrogen, full strength, taking great care 
that the liquid should be thrust into the discharging sinuses, in order 
to secure the complete destruction of the microbian element ; the pus 
is also destroyed, and the cleansing of the sore is made perfect. 
As a local dressing a double thickness of surgical lint should be 
♦Glycozone, administered three times daily in the proportion of i teaspoonful diluted in a 
wineglassful of water, will prevent the disorders of the stomach. 33 
soaked into Glycozone and applied to the sore ; and an over-covering 
of oiled silk should be used. 
The above local treatment does not exclude the internal medi- 
cation. 
Yellow Fever.-According to the recent researches made by Dr. 
Paul Gibier, of the Faculte de Medecine de Paris, France, it seems to 
be a positive fact that Yellow Fever is caused by bacteria which are 
located in the intestines. This theory being supported by other 
prominent bacteriologists, the most logical treatment, in order to sub- 
due this intestinal infection, is to administer some laxatives in connec- 
tion with antiseptic remedies. 
The use of bichloride of mercury solution has been recommended 
as a rectal injection, although it should be absolutely condemned, 
owing to its corrosive and toxic properties. 
A 3 per cent, solution of bichloride of mercury is equivalent, as a 
bactericide, to a 2 per cent, solution of Peroxide of Hydrogen (medic- 
inal). Then a 1 per cent, solution of Peroxide of Hydrogen (medic- 
inal), which corresponds to a 41 volume capacity, has the same bac- 
tericide power as a per cent, solution of bichloride of mercury. 
(See on page 8, " Comparative Tests.") 
Treatment.-By means of a glass or a hard rubber syringe the 
physician should prescribe a rectal injection, administered three times 
daily, with one-half pint of a mixture made of 
1 ounce of Marchand's Peroxide of Hydrogen (medicinal) 
with 3 to 4 ounces of lukewarm water ; 
and he will obtain the same disinfectant action as he would obtain by 
using half a pint of a i| per cent, bichloride of mercury solution. The 
use of such a quantity of bichloride of mercury should evidently kill 
both the germs of the disease and the patient. 
WOMEN'S WEAKNESSES. 
Whites, Leucorrhcea, etc.-These very troublesome and pain- 
ful diseases require not only an appropriate internal medication, but 
also a powerful local antiseptic treatment. 
All the remedies prescribed to subdue these affections are more or 
less injurious on account of their corrosive, irritating, or poisonous 34 
properties ; and, in fact, they produce very often an aggravation of 
the disease. 
On the contrary, Marchand's Peroxide of Hydrogen (medicinal), 
which is more powerful than any one of these antiseptics (see page 
8, " Comparative Tests "), has, by its stimulating action upon the 
diseased mucous membrane of the vagina, a prompt and curative 
effect. 
Treatment.-By means of either a glass or a hard rubber syringe, 
copious injections should be administered at least twice daily, morn- 
ing and evening, with a mixture of 
i to 3 ounces of Marchand's Peroxide of Hydrogen (medicinal) 
with i pint of lukewarm water, 
according to the tenderness of the infected surface. 
The above treatment will promptly accomplish an absolute cure 
where all other remedies have failed. 
In cases of acute inflammation or ulceration of the womb, injec- 
tions should be administered copiously and repeatedly morning and 
evening, with a mixture made of 
2 to 4 ounces of Marchand's Peroxide of Hydrogen (medicinal) 
with i pint of lukewarm water.* 
Gonorrhoea.-This disease is known to be characterized by a local 
infection of the urethral canal, which is caused by bacteria of the 
gonococcus species. 
Those germs, as well as the unhealthy excretions which are present, 
are readily destroyed by Marchand's Peroxide of Hydrogen (medic- 
inal), and the physician may prescribe three injections every day, to 
be administered by means of a glass or hard rubber syringe, with a 
mixture of 
i ounce Marchand's Peroxide of Hydrogen (medicinal) 
with 4 to 8 ounces of water, 
according to the degree of inflammation ; retain this liquid in the 
canal for a few seconds, f 
* Besides the Peroxide of Hydrogen treatment, in chronic cases it is necessary to apply the 
Glycozone on lint into the vagina morning and evening. 
+ In case of chronic Gonorrhoea, or Gleet, besides the above treatment the physician should 
prescribe one injection every night with Glycozone. 35 
The dangers of stricture resulting from the use of caustic or 
astringent remedies are absolutely avoided, and the cure is effected in 
half the ordinary time if the above treatment is earnestly followed. 
The appropriate internal medication should be prescribed by the 
physician. 
LIST OF DISEASES WHICH ARE SUCCESSFULLY TREATED BY 
MARCHAND'S PEROXIDE OF HYDROGEN (MEDICINAL) AND BY 
"GLYCOZONE." 
The fact that Marchand's Peroxide of Hydrogen (medicinal) is the 
most powerful pus-destroyer is so well known among physicians who 
have used it that it is acknowledged to be unsurpassed as a cleansing 
agent for pus-discharging surfaces, especially in cases otherwise difficult 
of access, for the instant it touches pus, " ozone " is set free, effervescence 
takes place, and continues until the pus is destroyed. Physicians may 
apply this remedy with perfect safety, and they will always obtain the 
most satisfactory results in the treatment of affections caused by germs 
or microbes. 
For example, Marchand's Peroxide of Hydrogen should be applied 
to the treatment of the following diseases : 
Open Boils, Open Abscesses, Mastoid Abscesses, Ulcers (syphilitic 
or not), Scrofulous Sores, Cancerous Sores, Bed Sores, Local Gan- 
grene, Broken Ampulla or Blisters, Aphthae or Ulcerations of the 
Mouth, Stomatitis, Burns, Herpes Zoster or Zona, Eczema, Skin 
Diseases, Itch, Piles, and all microbian affections. 
Treatment.-As a rule, the above-mentioned diseases should be 
treated as follows : 
First-By means of a glass dropper, or otherwise, apply Mar- 
chand's Peroxide of Hydrogen (medicinal) to the sore, and take care 
not to remove the white foam which is generated when this remedy 
comes in contact with the diseased surface ; let it stand until it disap- 
pears, which occurs in a few minutes. 
Then, by means of a glass dropper or a soft camel's-hair brush, 
apply the Glycozone to the sore and cover it with a double thickness of 
surgical lint soaked in Marchand's Peroxide of Hydrogen (medicinal).* 
* It is advisable to apply both " Marchand's Peroxide of Hydrogen (medicinal) " and " Glyco- 
zone," full strength, but it is not always possible, in cises when the sore is exceedingly tender. 
When such is the case, the Peroxide of Hydrogen (medicinal) should be diluted with water, and 
the Glycozone should be thoroughly mixed with chemically pure glycerine. 36 
THE USE OF MARCHAND'S PEROXIDE OF HYDROGEN 
(MEDICINAL) IN DENTAL SURGERY. 
I beg to call the attention of the dental profession to the fact that, 
owing to its wonderful bactericide properties, the Peroxide of Hydro- 
gen (medicinal) which I manufacture is the most powerful remedy 
to apply in order to cure the dental affections which are known to be 
caused by germs or microbes, such as, for example : 
Alveolar Abscesses and Abscesses of the Inferior Maxilla. 
Laceration, Inflammation, and Ulceration of the Gums ; Stomatitis. 
Necrosis and Caries of the Teeth. 
The profession well know that the therapeutical agents used for the 
treatment of these diseases have been as follows : 
Chloride of Sodium.-Salicylic Acid.-Chloride of Zinc.-Nitrate of Sil- 
ver.-Creosote, and Carbolic Acid. 
With the exception of chloride of sodium, which has no appreciable 
destructive action upon the microbian element, the other above-men- 
tioned remedies are poisonous, and, owing to their corrosive proper- 
ties, the dentists cannot always limit their action to the affected parts. 
The creosote and carbolic acid have such an offensive odor that 
they should not be used at all. (See foot-note, page 9, article headed, 
" The Dangers of Carbolic Acid.") 
On the contrary, Charles Marchand's Peroxide of Hydrogen (medic- 
inal) is absolutely harmless ; it is almost odorless and tasteless.* 
By the healing power of this wonderful remedy, the diseased surface 
is made healthy and the surrounding tissues remain in their normal 
condition. 
GENERAL DIRECTIONS. 
Alveolar Abscesses and Abscesses of the Inferior Maxilla 
-Treatment.-When an Alveolar Abscess is caused by any constitu- 
tional derangement, internal medication would necessarily have to be 
prescribed. 
The local treatment demanded is such as will destroy the accumu- 
lated pus. 
* It is used without danger or risk of poisoning the patient, and yet it is the strongest bacteri- 
cide and purifier known. (See " Comparative Tests," on page 8.) 37 
At first, the abscess should be broken by a surgical operation or 
otherwise, then the cleansing and destruction of pus will be accom- 
plished instantaneously, as follows : 
By means of a silver, gold, or platinum syringe, administer into the 
cavity, morning and evening, one or two injections with a mixture of 
i part Ch. Marchand's Peroxide of Hydrogen (medicinal) 
with 3 to 4 parts of water. 
In the treatment of Abscesses of the Inferior Maxilla, where there is 
no free egress for the pus and debris, much more energetic treatment 
is necessary, and the dentist need not hesitate to administer injections, 
morning and evening, with a mixture of 
i part Ch. Marchand's Peroxide of Hydrogen (medicinal) 
with 2 parts of water. 
Besides the above local treatment, the mouth should be kept clean 
by frequent washings with a mixture of 
i tablespoonful of Charles Marchand's Peroxide of Hydrogen (medici- 
nal), diluted in half a tumblerful of tepid water.* 
By following this treatment, the diseased tissues become healthy 
after one or two applications, and an absolute cure is effected in half 
the ordinary time. 
Laceration, Inflammation, and Ulceration of the Gums- 
Stomatitis-Treatment.-Charles Marchand's Peroxide of Hydro- 
gen (medicinal) is the most powerful remedy which may be applied in 
order to subdue these very tenacious and painful affections. 
It should be used freely and repeatedly as a tooth-wash, morning and 
evening, in the following proportion : 
i ounce Medicinal Peroxide of Hydrogen, 
diluted with half a pint of water. 
Rinse the mouth well, and retain this liquid in the mouth for one 
minute or so at each washing. No injurious action whatever upon the 
enamel of the teeth need be feared. 
* In chronic cases, during four or five days, floss silk or absorbent cotton, moistened with 
Glycozone, should be applied immediately after each cleansing of the cavity. 38 
The gums are strengthened by this treatment, healthy granulations 
develop very rapidly, and an absolute cure is quickly effected. 
When the above diseases of the gums are caused by constitutional 
derangement, internal medication would necessarily be prescribed. 
Necrosis and Caries of the Teeth.-Caries is a very common 
cause of Necrosis. Excessive medication, especially with mercury, will 
sometimes produce partial, and, occasionally, total Necrosis. 
The profession know that the most common agents that injure the 
teeth are originated in the mouth by the decomposition of animal and 
vegetable matter. 
Inflammation of the mucous membrane of the mouth is a common 
result of diseased teeth. 
The Caries may be constitutional or local, and, if constitutional, the 
dentist knows that it may be modified by therapeutic treatment of the 
general system. 
In all cases of Caries, the aggravation of the disease will always be 
prevented by using frequently and copiously, as a tooth-wash, a mixt- 
ure of 
i to 2 ounces of Ch. Marchand's Peroxide of Hydrogen (medicinal), 
with half a pint of water. 
Rinse the mouth well, at least morning and evening, and retain this 
liquid in the mouth for one minute or so at each washing. 
When the Caries is local, an absolute cure is promptly accomplished 
by the above treatment. 
MARCHAND'S PEROXIDE OF HYDROGEN (MEDICINAL), 
USED AS A WASH IN THE TREATMENT OF THE 
INFLAMMATORY DISEASES OF THE EYES. 
GLYCOZONE IS THE MOST POWERFUL HEALING AGENT FOR 
THESE CONTAGIOUS DISEASES. 
Catarrhal Conjunctivitis, or Ophthalmia-Causes.-The pro- 
fession well know that all the forms of Conjunctivitis which are 
accompanied by secretion are caused by germs which develop under 
more or less favorable circumstances, producing a local infection which 
is contagious to the highest degree. 39 
The virulence of the contagion increases with the impurity of the 
atmosphere, and this disease is communicated by conveyance of 
secretion from one to another, by towels, handkerchiefs, etc., with a 
prodigious rapidity. 
Besides a proper ventilation, it is necessary to isolate sick people, 
and also to keep them perfectly clean, in order to prevent the contagion ; 
for instance, when any form of Conjunctivitis appears in a public insti- 
tution it is urgent to put all the affected persons apart from the healthy. 
Numerous analyses which I have made in order to ascertain the 
nature of the remedies ordinarily applied in the treatment to this 
disease show that they are as follows : 
Nitrate of Silver.-Sulphate of Zinc.-Sulphate of Copper.-Bichloride oi 
Mercury.-Red Oxide of Mercury.-Carbolic Acid.-Alum.-Sugar of Lead. 
-Tannin.-Borax.-Boracic Acid.-Sulphate of Atropine.-Cocaine. 
Although some of these remedies have a destructive action upon 
the microbian element which is the cause of this disease, such remedies 
should be condemned, owing to their corrosive and irritating properties, 
In some instances they have the most injurious effect upon the cornea, 
and very often destroy not only the germs of the disease, but also 
weaken or destroy the optic nerves, and for this reason their use proves 
more dangerous than the disease itself. 
Tannin, borax, and boracic acid are not dangerous remedies; but 
their bactericide power is so feeble that a cure could not be effected by 
their action, since they cannot remove the cause of the infection. 
On the contrary, Marchand's Peroxide of Hydrogen (medicinal) 
removes the cause of the disease, and Glycozone, by its strength- 
ening and curative action, makes the mucous membranes of the eye 
grow stronger daily. 
Treatment.-First the eyelids should be cleansed by a thorough 
washing made with a mixture of 
i ounce Marchand's Peroxide of Hydrogen (medicinal) 
with 2 pints of lukewarm water ; 
then, by means of a glass dropper, apply to the inner portion of the 
eye, next to the nose, one, two, or more drops of Glycozone every night 
before retiring and first thing in the morning. 
If no dropper is at hand, apply the remedy with a soft camel's-hair 40 
brush, dipped in the Glycozone, to the outer edge of the eye, with an 
outward motion of the brush, or it may be applied with the finger. In 
whatever manner the Glycozone is applied, it penetrates the inner sur- 
face of the eye by simply opening and shutting the eye repeatedly for a 
few times. 
At first it causes smarting, and often very severe pain for a few 
seconds, but it is only momentary and soon passes away. 
Purulent Conjunctivitis - Ophthalmia Neonatorum, or 
Ophthalmia in Children.-The oculists well know that the Ophthal- 
mia Neonatorum, or Ophthalmia in Children, is much more dangerous 
in its consequences than the Catarrhal Conjunctivitis. 
This disease, which is the most frequent source of blindness in 
children, can always be cured if treated as follows : 
First cleanse the eyelids by a thorough washing with a mixture of 
i ounce Marchand's Peroxide of Hydrogen (medicinal) 
with i pint of lukewarm water. 
This should be done three times, or at least morning and evening, 
every day. 
Each cleansing should be immediately followed by the application 
of Glycozone. (See explanations given on page 39, article headed 
" Catarrhal Conjunctivitis.") 
Granulated Eyelids.-Same treatment as Catarrhal Conjunctivitis. 
In all diseased conditions of the eyes the patients should expose 
themselves to air-draughts or bright light as little as possible, and the 
bowels should be kept open by a suitable internal medication. 
SUPPURATIVE AND INFLAMMATORY DISEASES OF THE 
EAR-TREATMENT BY MARCHAND'S PEROXIDE OF 
HYDROGEN (MEDICINAL) AND 4i GLYCOZONE." 
Owing to its wonderful bactericide properties Marchand's Peroxide 
of Hydrogen (medicinal) is of great value in cases of obstinate 
chronic suppuration of the middle ear, especially in such cases where 
it is difficult to reach all the suppurating tract by any local agent. 
The fact that it can be forced through the osseous sinuses without 
danger highly commends its value in the different diseases just men- 
tioned. 41 
In case of profuse suppuration, the cleansing and destruction of 
pus should be made perfect by applying the remedy in the following 
manner : 
By means of either a glass or a hard rubber syringe inject into the 
cavity, morning and evening, half an ounce of Marchand's Peroxide of 
Hydrogen (medicinal), full strength ; let the remedy act during two or 
three minutes, and then apply into the ear, as a dressing, a small 
quantity of absorbent cotton well impregnated with Glycozone. 
Two washings with Peroxide of Hydrogen and two dressings with 
Glycozone, applied every day, will cure the most obstinate chronic 
case in a very short time. 
When the disease is not chronic, the suppuration being relatively 
limited, instead of applying Marchand's Peroxide of Hydrogen (medic- 
inal), full strength, it should be diluted with lukewarm water, in the 
proportion of half-and-half. 
The local dressing should be always made with pure Glycozone, 
as heretofore explained. OPINION OF THE MEDICAL PROFESSION. 
See a report on Hydrogen Peroxide, read at the Indiana Institute of Homoeopathy, May 19, 
1885, published in the Medical Era July, 1885, and republished in response to numerous requests, 
after having been revised, in the number issued April, 1886. By Wm. B. Clarke, M.D., Indian- 
apolis, Ind. 
In this very elaborate article Dr. Wm. B. Clarke says : " I have used several makes of Peroxide 
of Hydrogen, foreign and domestic, and find the purest and best to be Ch. Marchand's Peroxide 
of Hydrogen (medicinal). 
See also a report on Hydrogen Peroxide read before the New York Society for Medico-Scientific 
Investigation, by W. W. Blackman, M.D., Brooklyn, N. Y. This report is published in the North 
American Journal of Homoeopathy, July, 1886, pp. 554 to 564. 
SOME CLINICAL FEATURES OF DIPHTHERIA AND THE TREAT- 
MENT BY PEROXIDE OF HYDROGEN. 
SURGEON METROPOLITAN THROAT HOSPITAL ; PROFESSOR DISEASES OF THROAT, UNIVERSITY 
OF VERMONT. 
GEORGE B. HOPE, M.D., New York. 
[Extract from the New York Medical Record, October 13, 1888.] 
The sentiment, so long divided, with regard to the constitutional or local inception of diphtheria, 
seems to be now almost universal in the direction of the latter theory. Consequently, in the light 
of this opinion, it is clear that the rational treatment must rest more on the recognition of some 
local agent which will surely destroy the specific germ before a full development of the constitu- 
tional infection is reached, rather than on any system of general medication which might be pre. 
sumed to act more or less as an antidote in combating the septic influences occurring in the course 
of the disease 
On account of their poisonous or irritant nature the active germicides have a utility limited 
particularly to surface or open-wound applications, and their free use in reaching diphtheritic 
formations in the mouth or throat, particularly in children, is unfortunately not within the range 
of systematic treatment. In Peroxide of Hydrogen, however, it is confidently believed will be 
found, if not a specific, at least the most efficient topical agent in destroyingthe contagious element 
and limiting the spread of its formation, and at the sapie time a remedy which may be employed 
in the most thorough manner without dread of producing any vicious constitutional effect. 
Although the Peroxide is by no means of recent date, its medicinal value has been chiefly confined 
to the cleansing of foul ulcers and suppurating wounds, and there is hardly more than a casual 
mention of its utility in the treatment of diphtheria previous to a paper of Dr. Mount Bleyer on 
this subject.* Quite independently of these observations, somewhat over eighteen months since, 
at the Metropolitan Throat Hospital, several cases of well-marked buccal diphtheria were treated 
with the Peroxide, with the effect of confirming in the most satisfactory manner the results 
obtained by Dr. Bleyer. The report of these cases was consequently omitted, pending the exper- 
iences it was supposed others would be quick to furnish on a more extended scale of the new 
remedy so warmly advocated. Among the somewhat small number of trial cases which have 
appeared at various times in the medical press, there are none in which a distinctly negative 
opinion is expressed, and where only a partial!}' satisfactory result is attained there has appeared 
to be sufficient cause to permit a reasonable explanation for the fact 
A further explanation for the uncertain results attending the use of the Peroxide lies in the 
direction of the preparation itself, as also in the manner of its topical application. The usual 
descriptions allow the diluted strength of from three to seven volumes of distilled water. Inasmuch 
as the efficacy depends upon the ozonized oxygen in solution, it has seemed desirable to rely on the 
full strength of the officinal preparation of fifteen volumes, especially when used in the fauces, where 
* The Medical Record, August 13, 1887. 43 
anyslight irritation from its acidity is not apparent. In all the cases treated, a fresh, standard 
Marchand preparation of fifteen volumes was that on which the experience of the writer 
has been based. An equally important element is in making the application in such a manner as 
to produce the most determined effect on the diseased tissues with as little local disturbance as pos- 
sible. Swabbing the tonsils and pharynx is the rough and ready method commonly resorted to, with 
the second motive of detaching, if possible, the membraneous formation. Such treatment is not only 
unnecessarily harsh toward the patient, but also in intrinsic efficacy falls far short in securing the 
best therapeutic value of the remedy. It is properly recognized that the removal of the membrane, 
unless it occurs spontaneously, is not favorable to the local conditions ; moreover, the glairy mucus 
coating the surface does not permit the application to come fairly in contact with the disease, or 
so superficially as to require the most constant repetition. The latter criticism holds the same 
bearing, only modified in a degree, to the hand-ball vapor and spray-producing instruments that 
have been recommended. 
A steady, coarse spray, with an air-pressure of twenty pounds or more, will in a few moments' 
time produce a more positive action than prolonged efforts to reach the fauces by means of cotton 
applicators. The force of the spray should be sufficient to cleanse at once the surface accumula- 
tions, as it destroys the necrosial elements with which it comes in contact. In this manner the 
removal of the debris and the action on the deeper structures go hand in hand. 
It will be noticed that immediately on contact with the Peroxide a white, cloudy coagulum is 
formed on and about the diphtheritic patches, readily floated off and exposing a more sharply 
defined and a flatter, smooth, and whiter base. Properly speaking, there is no liquefaction 
of the exudation, but the decomposition of the inflammatory products is so complete that the cells 
are broken up and freed from the entangling fibrous net-work beneath. In a particular instance, 
in the case of apparently a continuous diphtheritic slough, involving the tonsils and extending in 
an unbroken line across the margin of the soft palate, a solitary application exhibited this effect to 
such a degree that the natural color of the mucous membrane appeared in spots as if the exudation 
might have bridged across sound tissue without as yet securing attachment to the sub-epithelial 
layers. 
How frequently the treatment is to be followed up depends to a considerable extent on the 
density as well as the area of the surface involved. It may be said, however, that two applications 
a day, in the great majority of cases, should be sufficient, if thoroughly performed, to arrest all 
danger of extension and accomplish the gradual resolution of the local formation. 
If the experience of the writer is confirmed, it is apparent how much time, trouble and unneces- 
sary handling is obviated when contrasted with the methods outlining hourly or half-hourly 
swabbing, or, as one has more frankly expressed it, "scrubbing," with nauseating applications, 
and culminating in the exhaustion of the patient, if not the most indifferent success. No reason- 
able objection can be raised either on the score of the expense or the difficulty of transporting the 
apparatus necessary, as small portable air-receivers can be readily obtained in the instrument 
shops, on the model of those devised by Codman & Shurtleff, of Boston, and which for the pur- 
pose are equally efficient as the larger stationary office fixtures. 
The more recent experience of Dr. Gifford (the Medical Record, September i, i888>, establish- 
ing the active germicidal properties of Peroxide of Hydrogen, rapidly diminishingin proportion to 
its dilution in what might be called a geometrical ratio, appears to emphasize in a marked degree 
the clinical observations on which the main features relating to its employment have been based. 
[Nezo ¥br& Medical Journal, Saturday, Feb. 2, 1888.] 
SOME PRACTICAL HINTS IN CONNECTION WITH INTUBA- 
TION OF THE LARYNX, AND A RESUME OF 206 CASES 
OF DIPHTHERIA OPERATED ON FROM 1886 TO 1888. 
By J. MOUNT BLEYER, M.D. 
(Extract.) 
. . . . Irrigation.-This is an admirable method of washing- away the products of the local 
lesion. I use a No. 8 soft-rubber catheter which is attached to a fountain-bag syringe ; the catheter 
is passed into the nostrils, first the right and then the left. The solution which is used is made by 
taking Peroxide of Hydrogen (Charles Marchand's), fifteen-volume solution, chemically pure, one 
ounce to twelve ounces of water. With this solution irrigate each nostril thoroughly. After this 
has been done, the next move is to wash out the mouth, pharynx, and larynx. If the child can be 
managed without forcing the mouth open, there is no need of the insertion of a gag ; but if not. use 
it. The patient is to be held well forward over a basin for the reception of the returning fluid. 
Make a second mixture of the Peroxide of Hydrogen of the strength of four drachms to twelve 
ounces of water. The catheter is passed well down into the larynx, the surrounding parts, and 
thoroughly irrigated. The fluids are very seldom swallowed, and if this fluid mixture should be 
swallowed there is no danger of poisoning, as it is a perfectly harmless antiseptic. The fluid is gen- 
erally immediately expelled by coughing. The mouth is to be kept wide open and the head well 
forward. By this mode of treatment patches of membrane, inspissated muco-pus. etc , can be 
washed away without difficulty and without pain. My experience with Peroxide of Hydrogen for 
the last four years has made me familiar with its varied use in the treatment of the diseases of the 
nose and throat. From a consideration of the action of Peroxide of Hydrogen upon the deposit 44 
of diphtheritic membranes, and the rapid reproduction of bacteria, it will at once be evident that 
the earlier the application of the remedy is adopted, the better. While the membrane is thin and 
friable, the action of this agent is thorough, quick, and effective ; the deposit melts down before 
the contact of it like Sugar in water, to be reproduced in a short time and again removed until the 
diseased tissue beneath can be plainly seen free from this characteristic covering. In this way, also, 
the spread of the membrane is checked and its limits often sharply circumscribed, until after 
some days, when the germinating power of the membrane is conquered and the poison ceases to 
produce its kind, no more deposit takes place, and the diseased tissues heal. In view of the 
rapid reproduction of bacteria already mentioned, it is evident that the applications should be no 
longer apart than two hours, or even less, according to the rapid reproduction of the mem- 
branes. Gargling may be practised by those who are able, but irrigation is preferred, as a more 
thorough application 'is thereby made. Irrigation is easily learned by the nurse, and there is 
absolutely no danger connected with its use. . . . 
For internal use I give the preference to Glycozone, which is chemically pure glycerine satu- 
rated with active ozone. It is to be used locally, as a substitute for bichloride of mercury, carbolic 
acid, permanganate of potash. This is the most powerful of all organic disinfectants and bacteri- 
cides. I give to a child over two years of age half a teaspoonful of Glycozone, well diluted with 
water or milk, every two to four hours, and under that age twenty drops. . . . 
ON THE MEDICINAL USES OF HYDROGEN PEROXIDE. 
E. R. SQUIBB, M.D., Brooklyn. 
Read before the Kings County Medical Association, February 5, 1889, during the discussion on 
diphtheria, and published in Gaillard's Medical Journal for March, 1889, p. 267. 
{Extract.} 
Throughout the discussion upon diphtheria very little has been said of the use of the Per- 
oxide of Hydrogen, or hydrogen dioxide, yet it is perhaps the most powerful of all disinfectants 
and antiseptics, acting both chemically and mechanically upon all excretions and secretions, so as 
to thoroughly change their character and reactions instantly. The few physicians who have used 
it in such diseases as diphtheria, scarlatina, small-pox, and upon all diseased surfaces, whether of 
skin or mucous membrane, have uniformly spoken well of it so far as this writer knows, and per- 
haps the reason why it is not more used is that it is so little known and its nature and action so 
little understood. Until within the last few years, except in a few manufacturing processes, it 
was chiefly known as a chemical curiosity, rarely seen because difficult to make. . . . 
In order to use it intelligently both the pharmacist and the physician must know something of 
its nature and properties. The name hydrogen dioxide expresses its composition, and its formula, 
H2O2 represents this name. Hydrogen monoxide, H2O, or water, can under certain conditions 
be made to combine with a second molecule of oxygen, the result being a water-like liquid, H2O2. 
This second atom of oxygen is very loosely combined, and the compound molecule is always on 
a strain to break up into water and oxygen, and when it breaks up, either slowly or rapidly, the 
oxygen separates in that nascent or most active and potent of its conditions next to the condition 
known as ozone. It is in the change of this breaking up into water and active oxygen that the 
latter element exerts its power, and the simple contact with organic matters, which are them- 
selves of complex nature and in condition to be changed, is sufficient to break up the dioxide and 
liberate the active oxygen. For example, some albuminoids are instantly changed by contact 
with hydrogen dioxide, as is shown by rinsing the mouth with a dilute solution, when the albu- 
minoid matters of the secretions are at once coagulated. Then, as all virus is albuminoid, 
whether propagative or not, it is destroyed or by coagulation rendered inert by simple contact 
with this agent, just as it is by contact with corrosive sublimate. This simple experiment of 
rinsing the mouth with a dilute solution of hydrogen dioxide and examining the discharged liquid 
can hardly fail to convince any one of the destructive potency of this active oxygen on some albu- 
minoids, and of its thoroughly cleansing effects upon the mucous surfaces. 
Now, if diphtheria be at first a local disease, and be auto-infectious-that is. if it be propagated 
to the general organism by a contagious virus located about the tonsils, and if this virus be, as it 
really is, an albuminoid substance, it may and will be destroyed by this agent upon a sufficient 
and a sufficiently repeated contact. . . . All kinds of spray and injection apparatus can now 
be easily obtained with fittings of hard rubber or glass, and such only should be used. 
A child's nostrils, pharynx, and mouth may be flooded every two or three hours, or oftener, 
from a proper spray apparatus with a two-volume solution without force, and with very little 
discomfort; and any solution which finds its way into the larynx or stomach is beneficial rather 
than harmful, and thus the effect of corrosive sublimate is obtained without its risks ordangers. 
Adults and children old enough to gargle the pharynx and rinse the mouth will get a better effect 
in this way. equally without much discomfort, from a three-volume solution ; and this applies not 
only to diphtheria, but also to scarlatina and other conditions of mouth and throat which require 
cleansing and disinfecting. As vaginal injections in cases of uterine cancer, etc., the strength 
must be increased until the disinfectant effect is obtained. A copious flushing out with a one- 
volume solution will often be sufficient. When wetted cloths are laid over external sores an over- 
covering of oiled silk should be used. 
As, in passing through several hands after leaving those of the maker, a little mismanagement 
may spoil the solution, some easily applicable tests of quality and strength are needed. 45 
So long as the solution will yield any active oxygen at all, it will give this off with active effer- 
vescence when poured onto a crystal or two of potassium permanganate. A solution containing 
only a quarter of its volume will give an effervescence so strong as to be misleading, and there- 
fore a quantitative test is needed. The following is a modification of a testing process given to 
the writer, with much other useful information, by Mr. Charles Marchand, of No. 10 West 4th 
Street, New York City, one of the oldest and best makers of Peroxide of Hydrogen, and one who 
supplies it to all parts of the country. . . . 
(The testing process is given in full on page 6.) 
If this agent is to be generally used in the treatment of diphtheria, as it well deserves to be on 
well established principles of action, it is very important that it be freely applied in the earliest 
possible stages of th^e disease, or while it is yet local; and therefore the agent should be easily and 
promptly accessible in places known to physicians, and not over a mile apart throughout a city, 
and in hands which know the agent well, and know how to keep it from change and to dispense 
it on physicians' orders. . 
If all pharmacists should undertake to keep it-or even all the prominent ones-it would soon 
share the fate of many other important medicines. , . . 
\Medical World, Philadelphia, Pa., June, 1889.] 
REPORT OF DR. R. CHAREST. 
PEROXIDE OF HYDROGEN FOR GONORRHOEA. 
Editor Medical World : 
I intended for some time to give the readers of the Medical World my favorite treatment for 
gonorrhoea and gleet, and I will take the opportunity of Dr. H. E. Stroud's offer to do so now. 
What I consider the simplest, quickest and least harmful treatment of gonorrhoea is Peroxide of 
Hydrogen in injection △ j to the 5 of distilled water, three to five times a day. 
Internally ten to fifteen grains of sodae bicarb., every three hours, to keep the urine alkaline. 
Walking to be avoided as far as possible, also beer, coffee, pepper, etc.; keep the bowels regular; 
use a syringe with tapered end and soft rubber tip for the injections. 
The Peroxide cf Hydrogen is used a good deal in commerce for bleaching purposes, so that there 
are different qualities of it on the market. 
For medical use it must be neutral to the litmus paper, odorless and colorless.* This kind you 
mav have from C. Marchand, io West Fourth Street, New York City. It must be kept at a 
temperature below 65° F., and no metal must come in contact with it. 
In writing to the above-named firm you will receive a pamphlet on this valuable remedy well 
worthy to be studied. 
I consider it the best germicide, as it is the least harmful and the most effective. For the past two 
weeks I have used it in the form of a spray, in one of the worst cases of eczema, of four years' 
standing, which had so far resisted the assaults of a dozen doctors, backed up by as many drug 
stores, and is now almost well. 
For syphilitic ulcers, soft chancres, diphtheria, ulcerated cervix, in fact, whenever there is pus 
or germs, this is the true remedy. 
In gonorrhoea, when the penis is highly inflamed, use the injection four to five times a day and 
the inflammation will rapidly be subdued, leaving theurethra in a perfectly healthy condition. 
The use of a suspensory is a great relief to the patient. 
The fl. ext. of black willow is very good for the erections. 
It is also the remedy par excellence in gleet, and there is nothing like its inhalation to cut short 
a paroxysm of asthma. 
I don't claim the Peroxide of Hydrogen (H2 O2) to cure gonorrhoea in three or eight days, for I 
don't believe there is anything that will do so without danger ; but it will cure it in three weeks and 
leave the unfortunate in the best of condition. 
St. Cloud, Minn, R. CHAREST, M.D. 
MEDICINAL USE OF HYDROGEN PEROXIDE. 
Editorial {Medical Record}. 
It is with pleasure that we peruse the new issue of Squibb's Ephemeris for July, 1889, confident 
as we are that whatever it tells us is in accord with the latest scientific advances, and is the result 
of careful thought and research. Among its articles is one by E. R. Squibb, on " Hydrogen 
Peroxide '' (published also in Gaillard's Medical Journal, March, 1889). This substance, which 
is one of the most powerful and at the same time the least harmful of all antiseptics and disin- 
fectants, has never come into general use, probably because it is so unhandy and spoils so readily 
(Dr. Scjuibb thinks it is because it is so little known and so little understood). It is made in large 
quantities by several large firms, but is used chiefly in the preparation of secret remedies. Its 
properties have been known for a long time. It is a compound of hydrogen and oxygen which 
is easily decomposed, yielding water and nascent oxygen which quickly oxidizes substances with 
* See page 5, article headed, " Important Information on Peroxide of Hydrogen." 46 
which it is in contact. The mere application of a solution of Peroxide of Hydrogen to certain 
albuminoid substances is sufficient to liberate its oxygen, which immediately coagulates the albu- 
minoid substance within its reach. Thus all sorts of virus, whether propagative or not, are 
destroyed, or by coagulation rendered inert in its presence, just as when strong corrosive subli- 
mate solutions are applied to them. The undiluted liquid peroxide is from its nature very un- 
stable, and on slight disturbance breaks up into water and oxygen with almost explosive 
rapidity. Therefore it is never made nor used undiluted, but is always dissolved in water. The 
"Peroxide of Hydrogen " which is furnished to the physician is really a solution of the pure 
liquid in water to which a little hydrochloric acid has been added, the acid being necessary to 
prevent rapid decomposition of the peroxide. A solution which will yield its own volume of 
active (nascent) oxygen is called a one-volume solution. The fifteen-volume solution (yielding 
fifteen times its volume of nascent oxygen) is that which is generally supplied by the makers. It 
is put up in pint bottles, containing about fifteen fluid ounces, sold at $9 a dozen. It is colorless 
and nearly odorless, tastes slightly acid, and leaves a slight, fleeting, not unpleasant after-impres- 
sion. Changes in this solution are indicated by the formation of bubbles of gas, which rise 
through the liquid or adhere to the sides of the bottle, and also by increased pressure within the 
bottles. At or below 590 F. the solution does not change for a long time. At 68° F. it does 
change, sometimes very rapidly, giving off oxygen gas. The solutions, whether strong or dilute, 
should be kept cool, outside the window of the sick-room in winter, and on ice or in ice-water in 
summer. The bottles in which the solutions are contained must not be held in the hand for any 
considerable time, as its warmth will cause decomposition. It must not be kept in contact 
with metals, nor applied by means of metal apparatus, as it not only ruins the instruments, but 
forms poisonous salts from the metal. It does not attack hard rubber or glass. It is not neces- 
sary to apply it as strong as when it comes from the maker. The ordinary fifteen-volume solu- 
tion sold is not injurious, but it is stronger than necessary, and to use it undiluted is wasteful. 
For the irrigation of a child's nostrils, pharynx, and mouth, a two-volume (made by adding two 
ounces of the fifteen-volume solution to a pint of water) solution may be used every two or 
three hours, and any part of this solution passing into the stomach will do good rather than harm. 
Adults and children who can gargle- especially in scarlatina and diphtheria-may use, as a 
gargle and mouth-wash, a three-volume solution (three ounces of fifteen volume solution to a 
pint of water). For vaginal injections, as in cancer, etc., a thorough washing with the one- 
volume solution will often suffice, but it may be necessary to increase the strength until the 
desired effect is produced. When cloths wetted in a solution are laid upon external sores they 
should be covered with oiled silk. The methods fortesting the activity of any solution are given 
in full, but need not be repeated here. Mr Charles Marchand, of No 10 West Fourth Street, 
New York City, is referred to as one of the best makers and furnishers of hydrogen peroxide. 
It is very necessary to get a good article, as careless preparation and after-handling may render 
it inactive. It is desirable that it should be applied very early when used in diphtheria, before 
the deposits in the throat have caused disease of the adjacent parts or of the general system. 
PEROXIDE OF HYDROGEN FOR THE RELIEF OF BITES FROM 
VENOMOUS INSECTS. 
[Page 148, Medical Record, February 8,1890.] 
Dr. Philippe Ricord, of Newark, N. J., writes : 
" Recently, while charging my atomizer with the full strength of fresh, standard Marchand 
preparation of Peroxide of Hydrogen, at the bedside of a child suffering with diphtheria, my atten- 
tion was attracted by the patient's mother, who appeared in pain, and stated that while taking up 
a blanket to wrap about her child she supposed she had been pricked by a needle, and on further 
examination discovered a hornet between the folds she had touched. Thereupon I immediately 
directed the Peroxide of Hydrogen spray into the wound, the surrounding tissues, in the few 
seconds that had elapsed, being swollen to such an extent as to distinctly mark its site. Instantly 
all pain ceased, and the swelling rapidly disappeared. In this case the wound was still suffi- 
ciently open to readily admit the Peroxide of Hydrogen, and the destruction of the virus was 
apparently in a moment so completely accomplished that no further treatment was after ward 
required,' May we not, therefore, infer that it is quite possible to annihilate many other poisons 
likewise, by the prompt application of so powerful yet safe an agent as the Peroxide of 
Hydrogen ? " TESTIMONIALS. 
Indianapolis, Ind., February 5, 1886. 
Dear Sir: I find Marchand's Peroxide of Hydrogen a very superior article, and shall take 
great pleasure in recommending it. Please send me, by express, 10 more 1 lb. bottles of the 15 
volume-the freshest you have. Yours truly, 
WM. B. CLARKE, M.D., 
No. 2 W. Market Street. 
Seward, Neb., December 23, 1886. 
Dear Sir : I have been using Charles Marchand's Peroxide as a local application to diph- 
theritic exudations, and as a dressing for pus-discharging surfaces, with unparalleled success. 
In my practice of twenty years' standing, I never have been acquainted with a remedy of equal 
potency in dissolving pus cell-formation, and arresting the condition on which it depends. 
Respectfully yours, 
J. H. WOODWARD, M.D. 
Charles Marchand, Esq. Brooklyn, January 21, 1887. 
Dear Sir : Your letter was received yesterday. 
I have tried the Glycozone with very gratifying results, and think it superior to the ordinary 
preparation of H2O2. 
I apply it as a dressing, on absorbent cotton, to sloughing and ulcerated surfaces, and think it 
superior to any other preparation I have ever used for that purpose. Applied twice daily it keeps 
the diseased surface perfectly clean and sweet, and rapidly stimulates healthy granulations. 
Its absolute purity does away with the necessity of neutralizing the acid found in ordinary 
preparations of H2O2, and, therefore, makes it most valuable as a remedial agent. I generally 
apply as a dressing 2 volumes strong. In ulceration of the cervix uteri, applied on absorbent 
cotton, it is "safe, sure, and speedy " in its action. Sincerely yours, 
Dr. W. W. BLACKMAN, 
Prof. Medical College, 23d Street and 3d Avenue. 
Boston, February 17, 1887. 
Dear Sir: Will you kindly forward me by express, as soon as possible, one-quarter dozen 
Charles Marchand's Hydrogen Peroxide (15 vol. Med., use) ? The package I received some time 
since I divided among three patients of mine, and to say that I am charmed with its action but 
feebly expresses it; I am already enthusiastic. Very truly, 
H. E. SMALL, M.D., 
690 Shawmut Avenue. 
Indianapolis, Ind., February 18, 1887. 
Dear Sir : Send me, by express, one dozen pound bottles of H2O2. 
Regarding Glycozone, I consider that it will be of great use to surgeons. I have observed that, 
applied to old sores, it at once renders them bright colored, and soon encourages healthy action 
by virtue of its power as an oxygenizer. Yours truly, 
WM. B. CLARKE, M.D. 
New York, April 14, 1887. 
Dear Sir: Speaking personally, Charles Marchand's Peroxide used at the Hospital (Met- 
ropolitan Throat Hospital) gives the most perfect satisfaction, both as a disinfecting and cleansing 
agent, among the chronic and severe cases of nasal and pharyngeal affections. 
Yours truly, 
Dr. G. B. HOPE. 
Holyoke, Mass., May 27, 1887. 
Dear Sir: Last March I read a paper before the Vermont State Dental Society, entitled 
" Growth, Development, and Treatment of Alveolar Abscess." This paper will be published in 
the July number of the Independent Practitioner, and will be illustrated. Peroxide of Hydrogen 
is my stronghold in the treatment of these abscesses ; in fact, is my main reliance. I have used 
the peroxide a little over fifteen months, but until I was at your place, the 13th of last month, I 
have had a great deal of trouble in getting it, and what I have had has been very weak. Among 
my dental friends the inquiry has been, " Where can we get good Peroxide of Hydrogen ? " Since 
using Charles Marchand s Peroxide I am very much pleased with it, and can heartily recommend 
it to my friends. Yours truly, 
GEO. A. MAXFIELD, D.D.S. 48 
Park Ridge, N. J., June it, 1887. 
Charles Marchand, Esq. 
Dear Sir : I have now used Charles Marchand's Hydrogen Peroxide and Glycozone for some 
time. I have been surprised at the results which I obtained by their employment as antiseptic 
agents when applied to ulcerated and gangrenous surfaces. In the treatment of all classes of 
wounds I consider them far superior to any of the most favorite methods now practised, leaving 
the surface clean and free from pus, promoting healthy granulations in a very short period, and, 
above all, is undoubtedly the cleanest dressing that can be had, as there is no bad smell when 
properly used. I have also used the peroxide with excellent results in ulcerative sore throat. In 
gonorrhoea I have used the Glycozone as an injection, with great satisfaction, the discharge 
ceasing immediately. I write these few lines to you to inform you of my first experience with 
these two remedies. My conclusions, so far. are that I shall never treat the above-mentioned 
diseases in any other way after this than with them. I shall in a few weeks have prepared the 
history of several cases which I have now in treatment, and which, 1 think, will prove beyond 
doubt, that in these two remedies we possess the most efficient means which we can desire, in the 
treatment of wounds and ulcerations. Yours truly, 
EUGENE JEHL, M.D. 
12 W. 39TH Street, New York, September 10, 1887. 
Dear Sir : Please send me three dollars' worth of Charles Marchand's Peroxide of Hydrogen, 
same as you furnished me last January. I found it an admirable article. 
Yours truly, 
HENRY C. HOUGHTON, M.D. 
Olean, N. Y., October 3, 1887. 
Dear Sir : Enclosed please find draft for $2.50. Please send me one pound of Charles Mar- 
chand's Peroxide of Hydrogen, 15 volumes solution, and one-half pound of Glycozone. The Per- 
oxide of Hydrogen received a few weeks ago is a splendid preparation, and has done me noble 
service. Please ship by express as soon as possible, as I am nearly out. 
Very respectfully, 
J. F. STEYNER, M.D. 
Newark, N. J., October 18, 1887. 
Mr. Charles Marchand, 10W. 4th Street, N. Y.: 
The bottle of Peroxide of Hydrogen sent proved very satisfactory. Please send a pint of the 
same, etc. Yours truly, 
ELEANOR HAINES, M.D. 
Newark, October 5, 1887. 
Mr. Charles Marchand. 
Dear Sir : In reply to your letter on the 5th, I will say that the " Glycozone " has had a good 
trial in nasal treatment. I found its results gratifying. 
I remain, yours respectfully, 
H. L. KNAUBER, M.D. 
Great Bend, Kan., December 13, 1887. 
Dear Sir : The Charles Marchand Peroxide of Hydrogen sent me is a charm. It is my strong- 
hold in the treatment of all abscesses, alveolar, etc., in which cases I have had under treatment 
since I received it ; my results have been a quick success in every case. I most heartily recom- 
mend it to dental profession. 
The Charles Marchand's Peroxide of Hydrogen is an excellent preparation ; no professional man 
should be without it. Dr. JNO. C. WALKER. 
St. Louis, December 23, 1887. 
Mr. Charles Marchand: 
I use the Peroxide of Hydrogen very much in diphtheria, and have always had trouble to find a 
reliable article. I shall use Charles Marchand's Peroxide exclusively hereafter. 
T. GRISWOLD COMSTOCK, M.D., 
507 N. 14th Street. 
Boston, January 17, 1888. 
I am pleased with the results of Charles Marchand's Peroxide of Hydrogen used as a thera- 
peutic agent, and have done my part in Boston among our pharmacists to draw their attention to 
it, as I made inquiries at all our first-class houses and found I could not obtain it. Dr. Blackman 
was the first person to call my attention to it, and from the high recommender he gave I wras led 
to use it in a minor surgical case a year ago. It delighted me, and I do not feel equipped in my 
office without it now. Yours respectfully, 
Dr. J. K. CULVER, 
698 Tremont Street. 
Baltimore, Md., February 23, 1888. 
Dear Sir .• I have been using Charles Marchand's Peroxide of Hydrogen (medicinal) for some 
time as ordered through Lilly. Rogers & Co., of this city, with very good benefit. When its value 
becomes better known by members of our profession and others, I have no doubt you will have a 
large sale. W. R. MONROE, M.D., 
1734 Bolton Street. 49 
New York, June 5, 1888. 
Mr. Charles Marchand. 
Dear Sir .• Allow me to commend your Peroxide of Hydrogen and Glycozone in the highest 
terms, as the most powerful of all antiseptics at present to me known. I have, after making a 
trial with the above-mentioned preparation in over one hundred cases of diphtheria in my clinic at 
the Eastern Dispensary, and with forty cases of diphtheria which have undergone the operation 
of intubation of the larynx by me, used in all these cited cases ozonized vapor and topical appli- 
cation, with fine camel's-hair brush of the five-volume solution of Peroxide of Hydrogen every 
three hours ; the Glycozone was applied in the same manner, only to repeat again with praise, 
that my expectations of these preparations have been fully realized. These have been recom- 
mended by me to all my colleagues, and spoken of the results that were obtained with such 
harmless, non-poisonous, curative, and powerful antiseptics. I make use of the Peroxide of 
Hydrogen and Glycozone in my office practice for nose, throat, and chest diseases, in all forms of 
application, as the ozonized vapor spray, local application, etc., with satisfaction to myself and 
patients, and hope that the further returns will agree with what my experience has taught me. 
In whooping-cough the ozonized vapor has rendered me extensive valuable service. 
Dr. J. MOUNT BLEYER, 
83 Second Avenue. 
Indianapolis, Ind., June 4, 1888. 
Dear Sir: We have used Marchand's Peroxide of Hydrogen in the past and liked it very 
much, but by some means were induced to try a peroxide manufactured in St. Louis, which we 
thought to be a good article for a time. 
Now we have decided to return to the Marchand's Peroxide of Hydrogen, and wish you to send 
us one dozen one-pound bottles at your earliest convenience. 
Yours, 
O. S. RUNNELS, M.D.. 
50 Circle Street. 
Brooklyn, N. Y., July 14, 1888. 
Dear Sir: Please deliver to bearer two bottles Ch. Marchand's Peroxide of Hydrogen. I have 
used it in bronchitis and consumption with gratifying results. 
Yours truly, 
E. H. MUNCIE, M.D., 
363 Tompkins Avenue, 
Topeka, Kan, November ax, 1888. 
I have never used anything that gives me such universal success in the treatment of diphtheria, 
catarrh, and many other equally difficult diseases to treat successfully, as Ch. Marchand's Peroxide 
of Hydrogen (medicinal). I really do notknowwhat I would do without it. Only a few months 
ago I would not have promised cures that I now have no hesitancy in guaranteeing. To me it 
approaches wonderland. I have done so much with it that has startled me, that I do not now 
think anything impossible in its therapeutic sphere. 
Dr. W. T. BRANSTRUP, Secretary Board of Health* 
Cambridge, Mass., February 6, 1889. 
Ch. Marchand, Esq.: 
Dear Sir : I am glad to learn that you have decided to put up your Peroxide of Hydrogen in 4 
oz. bottles. 
I think that this departure will be appreciated by the dental profession as soon as it becomes 
known. Dentistshave heretofore had great difficulty both in procuring and keeping such a desir- 
able compound. Now we shall be enabled to have a fresh supply to uncork at more frequent 
intervals. Dr. H. E. CUTTER, 
432 Harvard Street. 
125 E. 25TH Street, New York, June 6, 1889. 
Mr. Ch. Marchand: 
In reply to your favor, relating to our experience in the French Hospital with your Peroxide of 
Hydrogen and Glycozone, I will state that after a year's trial in a great many cases of obstinate 
chronic ulcers, carbuncles, and wounds of all types, we have obtained such favorable results that 
we now employ them almost exclusively. 
Their advantage over other disinfectants and antiseptics is, in my estimation, their easy applica- 
tion, quick action, and freedom from danger of absorption. 
Yours very truly, 
J. J. HENNA, M.D. 
Delaware, O., September 28, 1889. 
Please send me two Hand Atomizers and Ozonizers for using Marchand's Peroxide of Hydro- 
gen, such as I got for my own use some time ago. 
I like the method of treating catarrh and throat troubles very much. 
Yours truly, 
M. P. HUNT, M.D., Surgeon. 50 
Quincy, III., November 18, 1889. 
I have been using Marchand's Peroxide of Hydrogen almost three years and feel no hesitation 
in asserting that for purity, strength, and stability it excels any make with which I am acquainted. 
I have employed it in a great variety of cases, both internally and topically, and have derived 
such uniform success with it that I have come to look upon Charles Marchand s remedy as one of 
the most valuable in the materia medica. 
My experience leads me to believe that its range of application has been limited too much to 
surgical affections. I employ it almost daily as an internal remedy and derive most gratifying 
results. It is not only useful in diseases of the respiratory organs, but also in almost every 
affection of the alimentary tract, in rheumatism, anaemia, chlorosis, neuralgia, typhoid, and a host 
of other diseases. 
Trusting that your Peroxide of Hydrogen may meet with the universal recognition which its 
merits deserve, I remain, yours respectfully, 
C. E. EHINGER. M.D. 
Office Board of Health, 
Topeka, Kan., December 19, 1889. 
Dear Sir: I am of the same opinion I was when I wrote to you on the 21st of November, 1888, 
only I am more charmed with the effects of Marchand's Peroxide of Hydrogen (medicinal). I 
have no words to express my admiration of its wonder-working powers. 
W. T. BRANSTRUP. M.D.. Secretary. 
Holyoke, Mass., December 24, 1889. 
I will say that Charles Marchand's Peroxide of Hydrogen (medicinal) is a necessity in my prac- 
tice and treatment of pulpless teeth, alveolar abscess, etc. It is my main reliance. 1 have used it 
about two years and I am perfectly satisfied with it. GEO. A. MAXFIELD, D.D.S. 
Olean, N. V., Dec. 24, 1889. 
Peroxide of Hydrogen is of inestimable value to me in the antiseptic treatment of old chronic 
sores, abscesses, and suppurating surfaces of all kinds. It is the ideal antiseptic in diphtheria, 
instantly removing all fetor and rapidly dissolving the membranes. I have used Glycozone in 
Leucorrhcea w'ith great satisfaction. I have used all brands of Peroxide of Hydrogen, but prefer 
the Marchand's, on account of its strength and keeping qualities. 
J. F. STEYNER. M.D., U. S. Examiner Surgeon. 
New York. December 24, 1889. 
Dear Sir: Let me endorse my statements of two years since, which I am able to do with 
emphasis Peroxide of Hydrogen is an agent unique ; no other takes its place in treatment of sup- 
purative disease of the middle ear ; it is of special value in the treatment of cases complicated by 
polypi and exuberant granulations ; also in necrosis, or caries, as it can be forced into cavities 
and sinuses,where it acts as no other applicant can act. In prescribing it I have sometimes been 
disappointed, but never when able to get your brand. Yours. 
H. C. HOUGHTON, M.D.. 
President of the College of the Neto York Ophthalmic Hospital, 
7 W. 39th Street. 
Indianapolis, Ind., December 25, 1889. 
Further experience only confirms my statement in the Chicago Medical Era, of July, 1885, that 
Hydrogen Peroxide is the most powerful (yet absolutely harmless) anti-putrid topical application 
known, and consequently unsurpassed as a cleanser of, and dressing for, pus-discharging sur- 
faces, and to prevent the process of pus-forming. Many cases of Pyaemia. Septicaemia and blood- 
poisoning would be prevented were its use more general While it is but fair to acknowledge 
that several large chemical works produce a good article of it, I am free to say that my preference 
is for the Marchand brand, because of the good work it has done for me. and because its maker is 
exclusively in the manufacture of it and its congeners, hence more likely to keep up and even 
improve, if possible, its high standard. Its principal congener, Glycozone, is as valuable, when 
indicated, as. in my opinion, it is when a slower yet more continued action is desired. 
WM. B. CLARKE, M.D., 
Secretary Indiana Institute of Homoeopathy. 
Ithaca. N. Y.. December 26.1889. 
I have used Marchand's Peroxide of Hydrogen (medicinal) in the treatment of Bronchitis, 
Asthma, and Amenorrhcea. caused from debility, with satisfactory results. I consider it a 
valuable tonic and antiseptic. A. BISHOP, M.D. 
St. Louis, December 27, 1889. 
I have used Ch. Marchand's Peroxide of Hydrogen (medicinal) daily for a number of years, and 
I must say it has proved itself a most valuable remedy. I use it diluted with water as a spray for 
catarrhal complaints, pure as a spray or a gargle for Diphtheria, and as a vapor when combined 
with glycerine for Hay Fever, Bronchitis, Asthma, and Phthisis. Have also used it as a cleans- 
ing wash for old ulcers. 
Have also used Glycozone, both internally and externally, and would not be without it. Its 
uses are manifold, and will amply repay any physician for using it. 
W. N. BAHRENBURG. M.D . 
019 Wash Street. 51 
Sidney, Ohio, December 25, 1880. 
I can only speak in the highest terms of Ch. Marchand's Peroxide of Hydrogen (medicinal) and 
Glycozone. Other preparations of Peroxide of Hydrogen have been recommended to me, but I 
only tried them,when I soon abandoned them to return to Marchand's, and in future shall only use 
this brand. It never fails to do its work. H. E. BEEBE, M.D. 
St. Louis, December 28, 1889. 
I have used Marchand's Peroxide of Hydrogen (medicinal), H2 O?, since about December, 1884, 
so that I regard myself as one of the first to recognize its peculiar virtues. I find medical gentle- 
men in societies speaking freely about it and extolling its merits. It is certainly most excellent 
in diphtheria and a host of other affections where there is any abnormal secretion set up. I have 
used it with good effect in some cases of fistula in ano, where the sinus was very much circum- 
scribed (short), and had not lasted long. As regards Glycozone, I found it to be very practical in 
ill-conditioned ulcers, in sinuses that are indolent and will not heal on account of the presence of 
a pyogenic membrane. T. GRISWOLD COMSTOCK, M.D. 
Buri.ington, Ia., December 29, 1889. 
Ch. Marchand, Esq. : 
I have used with great satisfaction both of your preparations. The Hydrogen Peroxide (medi- 
cinal) is the best I have ever used ; but to the comparatively new drug, " Glycozone," I must give 
all praise. I am simply surprised and delighted with results following its use. In all cases where 
an emollient seems indicated it has proven more than satisfactory. I can confidently recommend 
Glycozone as an application to allay irritation, alleviate inflammatory soreness, swelling and pain. 
I have been remarkably successful with it in treating Phagedenic Pericementitis, commonly known 
as Pyorrhoea Alveolaris. I use it in all abscessed conditions. I have delighted several patients 
by correcting an offensive condition of the breath. In a word, I cannot now think of being with- 
out Glycozone, and to that end I lecture to my class at the State University. I am sorry my time 
will not allow me to detail cases and to say more in favor of Glycozone, as I know of its value. 
One great advantage Glycozone has is the fact it will not coagulate albumen ; at least it so re- 
sponds to my tests with egg albumen, R. L. COCHRAN, D.D.S., 
State University of Iowa. Dental Department. 
Marietta, Ga., December 30, 1889. 
I have used Ch. Marchand's Peroxide of Hydrogen (medicinal) in many cases of diseases of the 
throat and nasal passages, and am using it now almost every day, and consider it a very useful 
remedy in all diseases of the mucous membranes. J P. R. CORTELYOU, M.D. 
Cambridge, Mass., December 30,1889. 
I am using Ch. Marchand's Peroxide of Hydrogen (medicinal) constantly in my dental practice, 
and find it to be a reliable compound, as it gives uniformly excellent results. 
H. E. CUTTER, D.D.S., 
432 Harvard Street. 
Lincoln, Neb., December 31, 1889. 
We have used Marchand's Peroxide of Hydrogen for two years, and can say that we are well 
pleased with it. We use it in Typhoid Fever where there is foul discharges, brown tongue, etc. ; 
ten drops in water every two hours will cleanse the mouth and tongue and dispel the bad smell 
from breath and discharges in from twenty-four to forty-eight hours. Also, it is well taken by 
the weakest stomach in foul or sloughing sore throat, Diphtheria, and Croup. It is a safe and reli- 
able remedy. Drs. BENTLEY & MAXON. 
St. Louis, December 31, 1889. 
I believe that I was among the first to use Peroxide of Hydrogen in this city years ago, and of 
various solutions that I have tried, I give Marchand's Peroxide of Hydrogen (medicinal) the 
preference over all others. The ordinary Peroxide of Hydrogen, as prepared and used for bleach- 
ing purposes, has an over-proportion of acid and is very irritating to mucous surfaces. As a 
cleansing and disinfecting agent, Marchand's Peroxide of Hydrogen is unequalled. I have used it 
extensively in diseases of the nose, throat, and ear, and even certain eye troubles, with the greatest 
satisfaction to myself, both in private practice and in hospital and clinical work. 
JAMES A. CAMPBELL, M.D., 
1729 Washington Avenue. 
Connellsville, Pa., January 1, 1890. 
I have had an extended trial of five years with Marchand's Peroxide of Hydrogen (medicinal), 
and in that time have probably used 200 bottles. I obtain it through Jno. Wyeth & Bros., of Phila- 
delphia. I have but lately received two dozen bottles. I employ it in Phthisis, Bronchitis, nose 
and throat affections, as a spray and by inhalation by means of hot water. Think it of great, very 
great value in Diphtheria. Have within fifteen days employed it as a spray in membraneous 
croup every hour or half hour : child of a girl-was given up on 8th of December by attending 
physician. I succeeded to this physician in the case, which I cured on the 23d day. Used, 
of course, heart stimulants, etc., and full feeding. I attribute the cure very greatly to employment 
of the Peroxide of Hydrogen. I. BRANDT ENOS, M.D. 52 
Upper Montclair, N. J., February i, 1890. 
Charles Marchand, Esq. . 
I wish to convey to you my appreciation of your efforts to supply the profession with a reliable 
Peroxide of Hydrogen. It will be conceded by the medical fraternity that no more powerful 
agent can be placed in their hands, for curative measures, than a preparation of oxygen, and to 
your efforts are we to-day enabled to command a reliable and comparatively stable agent. 
I am induced to speak well of your special preparation through my practical experience with it. 
My most extended acquaintance with your Peroxide and Glycozone has been in the use of them 
in cases of Nasal Catarrh and abnormal uterine discharges. 
In this peculiar class of troubles I can fully coincide with all of the enthusiastic utterances 
which have from time to time come within my hearing. 
I can also add that I am fully convinced that no application equals your two preparations in the 
dressing of wounds, more especially those showing marked loss of tissue. This I nave proved in 
a large number of accidents to railway employees, where the conditions for rapid healing have 
been of the worst character, and have not failed to get marked improvement after the systematic 
use of both medicaments. Dr. MORGAN WILLCOX AYRES. 
Baltimore, January 1, 1890. 
The topical application of oxygen is capable of immense benefit. In the pitting of small-pox I 
most earnestly advocate and urge its use, either in the form of Glycozone or properly diluted 
Marchand's Peroxide of Hydrogen (medicinal). I believe much deformity can be obviated by its 
use, and the force of the disease lessened. Foul and indolent ulcers, when treated by iodoform, 
carbolic acid, etc., are apt to poison the patient; such cases have occurred. With oxygen that 
would be impossible. In large suppurating sores, where the various germicides are dangerous on 
account of the large breach of continuity and absorption of the poison, the topical application of 
oxygen is perfectly safe, and, to say the least, equally efficacious. 
Ophthalmia is advantageously treated by the topical application of either the Peroxide or Gly- 
cozone. Styes can be aborted if Glycozone be rubbed on the lids at the commencement ; and as 
styes are painful and the swelling and pain last for a few days, the use of Glycozone is satisfac- 
tory to both patient and physician. In nasal catarrh, when the mucous membrane is dry and 
crusts form, prompter and more satisfactory results can be obtained from Glycozone than from 
any other means known. In the various chronic inflammations of the throat which are ordinar- 
ily obstinate to treatment, I have frequently satisfactorily treated by the Peroxide (diluted), espe- 
cially when the orifice of the eustachian tube was closed by swelling, and the patient rendered 
uncomfortable by temporary deafness and ringing in the ears. 
Dr. J. H. DeWOLF, 
519 N. Charles Street, i-:altimore, Md. 
35 W. 49TH Street, New York, January 1,1890. 
I have made constant and extensive use of Marchand's Peroxide of Hydrogen (medicinalI and 
Glycozone ever since they were first placed on the market, and found bath of these remedies to 
fulfil all the claims made for them. Dr. F. G. WELCH. 
Pemberton, N. J., January 1, 1890. 
I have used Marchand's Peroxide of Hydrogen (medicinal) in cases of debility arising from 
asthma, and consider it one of the most valuable tonics and restoratives in the materia medica. I 
consider Marchand's preparation among the very best. W. L. WOODRUFF, M.D. 
Brooklyn, N. Y., January 3, 1890. 
I am pleased to say that I am delighted with the beneficial results I have experienced in the use 
of Marchand's Peroxide of Hydrogen (medicinal). In asthma, catarrhal diseases of the nose and 
throat, it is wonderfully efficacious and very convenient of application. 
EDWARD H. ASHWIN, M.D., 
Major and Surgeon ^th Regiment, National Guard, N. K. 
Dunkirk, N. Y., January 4. 1890. 
My experience with Marchand's Peroxide of Hydrogen (medicinal) in practice is very limited. 
I have used it chiefly for cleaning out foul pus in suppurative otitis, and have found it very satis- 
factory for this purpose. Have also used it for a similar purpose in purulent conjunctivitis with 
good results. Dr. GEORGE E. BLACKHAM, 
305 Central Avenue. 
Boston, January 2, 1890. 
Ch. Marchand, Esq.: 
In answer to your inquiry concerning my present opinion of your Peroxide of Hydrogen 
(medicinal), let me say that it retains in my armament the same high position as formerly ; 
added experience gives a wider range to its usefulness. Without writing you a long article I 
could hardly explain my uses of it, for there is not a form of depression of the system in which 
the preparation is not of value, if intelligently handled. I have used all the common brands of 
peroxide, and commend yours most heartily. 
Glycozone will cure gonorrhoea in a safe and painless manner; it is equally efficacious in the 
leucorrhcea that accompanies cervical ulceration : it destroys diphtheritic exudations ; and, in 
general, wherever pus is formed in the economy. Glycozone is my most valued helper : hence its 
maker may feel sure of the friendly regard of HERBERT E. SMALL. M.D., 
690 Shawmut Avenue. 53 
Louisville. Ky., January 6, i8go. 
I have used Marchand's Peroxide of Hydrogen (medicinal) for several years past, and I con- 
sider it one of |the most valuable drugs the surgeon can call to his aid. I know of nothing that 
will take its place in a number of different conditions that the surgeon might meet daily. As a 
cleanser, stimulant, and antiseptic in the treatment of all suppurating cavities or surfaces it has 
no equal. A. MORGAN VANCE, M.D. 
Pittsburgh, Pa., January 6, 1890. 
Would say, in connection with my specialty, "Electro-therapeutics," I have used Marchand's 
Peroxide of Hydrogen (medicinal) in catarrhal diseases, nasal and pharyngeal, quinsy, tonsilitis, 
and conjunctivitis with most satisfactory results. S. L. JOHNSON. M.D., 
No. 30 Ninth Street. 
Jerseyville, III., January 6, 1890. 
From the experience I have had with Marchand's Peroxide of Hydrogen (medicinal), I am well 
pleased with it, and as a mild, harmless, and efficient remedial agent, either alone or accom- 
panied with Glycozone, wherever an antiseptic is needed. WM. W. ESTABROOKE, M.D. 
Lafayette, Ind., January 6, 1890. 
I have used Marchand's Peroxide of Hydrogen (medicinal) and Glycozone with the most grati- 
fying results to my patients and to myself. As disinfectants and curative agents Peroxide of 
Hydrogen (medicinal) and Glycozone have no equal. Marchand's H2O2 will prevent and remove 
the discoloration of bruises. Hence it will be found very useful in cases of accidental injuries 
about the face or eyes. I can heartily recommend both preparations as elegant and powerful 
curative remedies. S. T. YOUNT, M.D., 
Vice-President Indiana State Medical Society, 
Boston, Mass., January 7, 1890. 
I have made use of ozone as an adjunct to treatment of throat diseases for years. I regard 
Marchand's Peroxide of Hydrogen as the best remedy. A. W. K. NEWTON, M.D., 
3 528 Tremont Street. 
Wakefield, Mass., January 8, 1890. 
I can unhesitatingly say I consider Marchand's Peroxide of Hydrogen (medicinal) the most pow- 
erful and harmless of all the antiseptics known to the medical world. I have used it in all diseases 
of the throat and nose with perfect satisfaction to myself and patient. Glycozone I have used in 
all diseases of the stomach, with gratifying success. I consider it an invaluable way of adminis- 
tering ozone. It is the germicide par excellence in foul sores and cancers. 
H. F. BRADBURY, M.D., 
Professor of Therapeutics, University of New Hampshire. 
69 W. 105TH Street, New York City, January 9, 1890. 
I am in constant use of Marchand's Peroxide of Hydrogen (medicinal), and find an increasing 
utility in it. It can be utilized in so many ways in these antiseptic days by the busy practitioner. 
IRETUS G. GARDNER, M.D. 
Baltimore,January 10, 1890. 
After several years' experience in the use of Peroxide of Hydrogen and Glycozone as thera- 
peutic agents, prepared by Prof. Ch. Marchand, of New York, the undersigned is prepared to say 
that he has found them, especially the former (mostly used by him), never failing so far as has been 
prescribed and used by him. He feels constrained to endorse all that Prof. Marchand claims for 
the use of oxygen, as set forth by him in his pamphlet, so far as his observation and experience 
extend. First, as being one of the most powerful and harmless of all antiseptics known. Second 
-as being especially adapted to the speedy relief and cure of diseases of the mucous surfaces, 
especially those of the mouth, nose, throat, bronchial tubes, and lungs ; also of the stomach and 
the entire alimentary or intestinal canal. Third- Externally for abscesses, sores, ulcers, etc. 
Fourth-For genito-urinary ailments, especially the reproductive organs of the female. Fifth- 
For general physical debility and nervousness, taken internally, it is rejuvenating, strengthening, 
and tonic Sixth-Oxygen is absolutely important and invaluable in cases of emergencies, to 
which the physician is often urgently and hastily summoned to administer, and to restore the 
dying or apparently dead : as in asphyxia, poisoning, fainting from almost any cause, from loss of 
blood in profuse hemorrhages, etc. 
The portable and convenient form of Peroxide of Hydrogen as prepared by Prof. Marchand, as 
well as Glycozone, commends the use of the same to the active and busy physician as being so 
readily used and easily carried in a vial or small bottle in his pocket or satchel for immediate use 
in unexpected cases of accident or heart failure, or persons in a supposed dying condition. 
W. ROBT. MONROE, M.D., 
Late Prof, of Therapeutics and Dean in the Baltimore Medical College. 
1734 Bolton Street. 
y Cincinnati, O., January 11, 1890. 
I have used Marchand's Peroxide of Hydrogen and Glycozone for one year, and have always 
found it reliable for certain specialties. I have made a clinical test in competition with other 
makes which have been recommended for similar purposes, and found it superior in efficacy. 
H. DWYER. M.D., 
90 E. 3d Street. 54 
Minneapolis, Minn., January 13, 1890. 
1 have the pleasure of saying that Marchand's Peroxide qf Hydrogen (medicinal) has been my 
favorite germicide for all abscessed cavities for many years. Have made tests as to its value as 
a germicide in our college laboratory, and have positive proof of its superiority over most of the 
popular agents for this purpose. I also use your formula of equal parts of H2O2 with glycerine 
for diphtheria. It is always my first application in specific vagina discharges. I use it for topical 
applications, and in its field it has first place with me. F. A. DUNSMORE. M.D.. 
226 W. 10th Street. 
* Pittsburgh, Pa., January 13, 1890. 
After considerable experience in the treatment of various maladies with Marchand's Peroxide 
of Hydrogen (medicinal) and Glycozone, I find that they possess all the antiseptic and healing 
properties that are generally claimed for them. I have used them in catarrh and lung disease, 
in ulceration of the external ear, abscesses, old sores, varicose and other ulcers, ulceration of the 
rectum and cervix uteri, and in most cases with better results than I have obtained with any other 
specific. J. S. DODGE, M.D., 
418 Penn. Avenue. 
Newark, N. J., January 14, 1890. 
I am both willing and glad to say that J have used Marchand's Peroxide of Hydrogen (medici- 
nal) in its various combinations, and alone, in hay fever, diphtheria, and in the treatment of 
wounds, with great satisfaction to myself and to my patients. Further, I have not seen equally 
as good results with Peroxide of Hydrogen made by other firms. 
B. H. B. SLIGHT, M.D., 
29 Chestnut Street. 
Denver, Col., January 14, 1890. 
Ch. Marchand, Esq.: 
I am in receipt of your favor of the 3d inst. I do not believe in reputable physicians giving 
their endorsement to proprietary or secret prep irations, for, as a rule, it is unprofessional and 
harmful. But I have no hesitancy in saying that I have used your Peroxide of Hydrogen quite 
extensively for nearly two years, and think it unquestionably the best antiseptic and cleansing 
remedy that I have ever used. Its property of dissolving morbid tissue, pus, and unhealthy 
mucus, while leaving the normal tissue unchanged, is unique. 
1 make constant use of it in the treatment of chronic Pharyngitis. Tonsilitis, Diphtheria, and 
kindred diseases T. W. MILES, M.D., 
1739 Stout Street. 
Warren, O., January 15, 1890. 
I have used Marchand's Peroxide of Hydrogen (medicinal) for three or four years, and feel 
pleased with its action. Dr. O. A. PALMER. 
New York, January 16, 1890. 
Ch. Marchand, Esq. : Yours received, and in reply would state that about a year ago we had 
some sample bottles of your Peroxide of Hydrogen (medicinal) and Glycozone, which we used on 
a severe case of burn with good effects. If you have been able to introduce your goods to our 
department through Dr. Rice, chemist, Bellevue Hospital, I would be glad to use, but am inclined 
to think that they come too high for such use. 
Dr. T. M. STRONG, Chief of Staff, 
Deft of Public Charities and Correction ; Homoeopathic Hospital, IV. I. 
Fultonville, N. Y., January 17, 1890. 
It gi-'es me much pleasure to speak very highly of the good qualities of Marchand's Peroxide of 
Hydrogen (medicinal) and Glycozone, both, and which I have used many times, and have yet to 
see a case not benefited by them. The first time I used Marchand's Peroxide of Hydrogen (medi- 
cinal) was upon a large, unhealthy ulcer of the leg. and I was simply astonished at the improvement 
made, and had never before seen such a change for the better, in so short a time, from the use of 
any outside agent. I consider it far superior to the bichloride of mercury, and with none of its 
disadvantages : and, when employed fresh, consider it the best agent we have in the treatment of 
al) wounds. HENRY W. POST. M.D. 
Thornton. Miss., January 18, 1890. 
I have found both Marchand's Peroxide of Hydrogen (medicinal) and Glycozone very desirable 
aids in the treatment of ulcerating wounds ana suppurating surfaces. Having used these pre- 
parations. I do not hesitate to recommend them as worthy of the highest consideration. 
CH. C. THORNTON, M.D. 
Little Falls, Minn., January '9, 1890. 
Ch. Marchand, Esq.: It is with pleasure that I give my appreciation of your Peroxide of Hydro- 
gen (medicinal), which has given me the best results in germ diseases. I would feel very unsafe 
to meet a case of diphtheria, for example, without your preparation of Hz O2, which is my strong- 
hold against microbes of all descriptions. I have found its inhalation to stop a paroxysm of 
asthma instantaneously. R. CHAREST, M.D. 55 
San Antonio, Tex.. January 20, 1890. 
From my extended experience of two years with Marchand's Peroxide of Hydrogen (medicinal) 
in various cases of ulceration and inflammation of the throat and lungs, used in connection with 
the Pneumatic Cabinet Apparatus, I have been highly gratified with its effects, and am induced 
to extend its field of usefulness as far as possible. B. F. KINGSLEY, M.D. 
Springfield. Mass.. January 22, 1890. 
I say, unreservedly, that Ch. Marchand's Peroxide of Hydrogen (medicinal) is one of the essen- 
tials in my practice. I know of nothing that can take its place, and its place is a larger one than 
could have been thought possible a few years since. C. T. STOCKWELL, M.D. 
Alexandria. Neb., January 22, 1890. 
I have used Marchand's Peroxideof Hydrogen (medicinal) for two years, and am satisfied that 
the results obtained by its use internally are not equalled by any other therapeutic means that I 
have tried, when the cases are selected with ordinary diligence and skill. As a dressing to old 
sores and to operation wounds, I have used it freely and with satisfactory results, especially to a 
case of amputation of the left breast and axillary glands, in a woman aged seventy-three. The op- 
eration was very extensive, as many axillary and other neighboring glands were involved, and 
the muscular tissue was so involved as to require removal down to ribs. The dressing was Mar- 
chand's Peroxide of H., in two volumes strength ; no pus, and a favorable course until gran- 
ulation set in. 
The operation was performed June 22, 1889, progressed uninterruptedly, and at this time shows 
no sign of returning. Should I ever have an occasion to again operate for cancer, I should cer- 
tainly use Marchand's Peroxide of H. as a dressing, as I believe it had some influence on the fav- 
orable result, particularly its non-recurrence at this date, for there were a number of minute infil- 
tration points that were not removed by operation, and had something not destroyed them they 
would have been manifest ere this time. JAMES F. THOMAS, M.D. 
Babylon, N. Y., January 25, 1890. 
I have used Marchand's Peroxide of Hydrogen (medicinal) in connection with internal treat- 
ment for several cases of Stomatitis, Bronchitis, Sore Throat, and commencing Phthisis, with 
gratifying results. A. J. WOODRUFF, M.D.. 
32 Main Street. 
Newark, N. J., January 27, 1890. 
My experience with Marchand's Peroxide of Hydrogen (medicinal), in the treatment of Diph- 
theria, has been most favorable, and I consider it to be the most powerful and harmless of all 
bactericides. I have used it in the treatment of Pertussis with most gratifying results. I have 
used Glycozone in the treatment of Chronic Gastric Catarrh, and found it to be a valuable remedy. 
PH. RICORD, M.D., 
433 High Street. 
Brooklyn, N. Y., January 27, 1890. 
In using Marchand's Peroxide of Hydrogen (medicinal) I have had the happiest results. In 
Diphtheria, as a spray, it has no equal. It has also done good work for offensive discharges, and 
as an external dressing it proved satisfactory. GEO. H. DOTY, M.D., 
48 Concord Street. 
Portland, Ore., February 1, 1890. 
I will only be too well pleased to add my voice to the thousands of others in praise of Marchand's 
Peroxide of Hydrogen (medicinal) and Glycozone. They certainly fill a niche in our materia medica 
that cannot be filled as well by any other preparations. I use them quite extensively in my prac- 
tice. Peroxide of Hydrogen is the best antiseptic yet discovered ; Glycozone, in its proper place, 
is equally as beneficial to humanity. R. H. RANDOLPH, M.D., 
313J First Street. 
419 Pine Street, Philadelphia, Pa., February 1, 1890. 
Marchand's Peroxide of Hydrogen (medicinal) has been a marked success in a number of cases 
of chronic, purulent inflammations of the middle ear, and Naso-pharyngeal Catarrh. It has also 
been of practical value in some cases of Phthisis. WM. W. VAN BAUN. 
239 King Street, West, Hamilton, Ont., February 4, 1890. 
My experience with Marchand's Peroxideof Hydrogen (medicinal) and Glycozone has been very 
satisfactory. I have been using it in cases of pulmonary and bronchial affections. In asthma I 
have found it most useful. W. G. STARK, M.D 
New Orleans, La., February 8, 1890. 
I have employed in my practice Marchand's Peroxide of Hydrogen (medicinal) with results very 
satisfactory to me. In all conditions characterized by pus formation I have been invariably 
pleased with its favorable action. I have used this preparation in ear troubles, womb troubles, 
carbuncles, and affections of the throat, where there existed more or less suppuration, and, as I 
say, with invariably good results. I do not, of course, expect it to do everything, but it certainly 
paves the way to successful treatment in all disorders associated with suppuration. I am not a 56 
subscriber to the germ theory of disease, and can account for its action and that of kindred rem- 
edies on very different and, to me, more satisfactory grounds. This is too considerable a question 
to be more than hinted at here Dr. C. H. TEBAULT. 
7 North Street, Lafayette Square. 
400 S. Alabama Street, Indianapolis, Ind., February 10, 1890. 
_ I consider Marchand's Peroxide of Hydrogen (medicinal) the best to be found for medical use. 
Glycozone is all you claim. Both are invaluable agents for the administration of ozone, the great 
germicide and tissue builder. B. P. WELLS, M.D. 
814 Seventeenth Street, N. W., I 
Washington, D. C., February 15, 1890. f 
Ch. Marchand, Esq.: 
I presume I have used as much Peroxide of Hydrogen (medicinal) and Glycozone in various 
venereal and skin affections as any of our physicians, and it is only justice to you to say that I have 
found your preparations remarkably effective-I may even say brilliantly so. There is hardly a 
day that I do not make use of either one or the other of them. 
In Gonorrhoea, a mixture of your Peroxide is the best injection I have ever used, and in slow- 
closing fistulae and sinuses the Glycozone has served me admirably. I trust the profession ap- 
preciate these preparations as I do. Dr. H. C. YARROW. 
Hudson, Mich., February 19, 1890. 
I would say that I have never found anything equal to Marchand's Peroxide of Hydrogen 
(medicinal) and Glycozone, especially in the treatment of Diphtheria and private diseases. In 
Diphtheria it is a specific. F. H. STROUD, M.D. 
1529 Lawrence Street, Denver, Col., February 19, 1890. 
I have used Marchand's Peroxide of Hydrogen (medicinal) and Glycozone in the treatment of 
abscesses, ulcerations, and catarrhal affections, with •uniformly good results. They are harmless 
and powerful bactericides. Dr. C. H. SCOTT. 
1266 Twenty-third Ave., Oakland, Cal., February 10, 1890. 
I began using Marchand's Peroxide of Hydrogen (medicinal) three years ago, and have found it 
a most valuable remedy in both acute and chronic inflammations of mucous membranes. It never 
fails me in giving results, and in gonorrhoea I consider it almost a specific. 
N. K. FOSTER, M.D. 
Mr. Charles Marchand. Brooklyn, Abril 16, 1890. 
Dear Sir: I have continued to use your Peroxide of Hydrogen (medicinal) during the past 
four years, and have always found it reliable for its uniformity, stability, purity, and strength. I 
use no other. Respectfully yours, 
W. W. BLACKMAN, M.D., 
519 Clinton Avenue.