A MANUAL OP THERAPEUTICS. RICHARD .lyjGHES, Jj.B.C.P. ED. (EXAM.), m!b.C.S. ENGL. LONDON: HENRY TURNER & CO., 77, ELEET STREET, E.C. AND 74, NEW BOND STREET, W. MANCHESTER: 41, PICCADILLY, AND 15, MARKET STREET. 1869. J. K. ADI.ARD, MTMTER, BARTHOLOMEW CLOSE. PREFACE. Much of wliat I have said in preface to the first part of this work is applicable also to the present volume. I have, moreover, in the “ Introductory ” Letter of the following series explained the prin- ciples which have guided me in this, the therapeutic pprtion of my undertaking. I have a very few words to add in this place. I have strictly kept before me the object I ori- ginally proposed, viz. to supply a manual of Homoeo- pathic practice suitable “for students and beginners.” I have written for these, and not for men of stand- ing and experience. I have attempted to put in a compact and accessible form those applications of remedies to disease which general consent has stamped as classical. These are the alphabet and grammar of Homoeopathic practice : the student must learn them, and cannot acquire the knowledge of them by chance or instinct. The practitioner of standing, on the other hand, is ever endeavouring to overflow and pass over these well-beaten boun- daries. He is seeking for remedies for diseases hitherto neglected, for more accurate adaptations of the medicines he has already learnt to apply, for new weapons from the great armoury of Nature where- with to make his strokes more effectual. For him I have indeed a suggestion here and there: but I VI PREFACE. have not his wants primarily in view. The develop- ment of the Materia Medica on the one side, the increased knowledge of disease on the other, are what he needs : and these things are beyond my present scope. But if I can make the study of Homoeopathy less bristling with difficulties, and the early attempts at its practice less tentative and hap- hazard, I think I shall have done good service. We should have been a larger band than we are, were it not for the many would-be students who have been repelled and the many beginners who have fainted and turned back for lack of a guide. If the present volume shall meet the kindly reception accorded to its predecessor I shall have every reason to be content. Brighton; February, 1869. CONTENTS. Letter page I. Introductory 1 II. “ SlMILIA SlMILIBUS” 13 III. The Dose and its Repetition—Change and Alternation of Medicine—Auxiliaries— The Duties of the Homoeopathic Phy- sician 27 IV. Blood Diseases. Plethora—Anaemia—Scurvy—Purpura... - 43 V. Blood Diseases (continued). Scrofulosis—Tuberculosis— Cancer 51 VI. Blood Diseases (continued). Gout—Rheumatism—Rheumatic Gout— Gonor- rhoeal Rheumatism 58 VII. Blood Diseases (continued). Febricula—Typhus—Typhoid—Relapsing Fever — YellowFever—Plague—Malignant Purpuric Fever 68 VIII. Blood Diseases (continued). Ague—Remittent Fever—Bilious Remittent 79 IX. Blood Diseases (continued). Variola— Varicella—Rubeola 87 X. Blood Diseases (continued). Scarlatina—Rotheln—Dengue—Miliaria 95 XI. Blood Diseases (continued). Hydrophobia— Glanders—Malignant Pustule— Syphilis—Sycosis 104 XII. Diseases of the Nervous System. Cerebral Meningitis—Phrenitis—Softening of the Brain—Apoplexy 114 XIII. Diseases of the Nervous System (continued). Mania — Melancholia—Dementia — Idiocy — General Paralysis of the Insane—Hypochon- driasis—Delirium Tremens 124 XIV. Diseases of the Nervous System (continued). Headache— Vertiqo—Insomnia—Injuries of the Head 133 VIII Letter page XV. Diseases of the Neryofs System (continued). Spinal Meningitis—Myelitis—Spinal Congestion —Spinal Irritation—Spinal Haemorrhage— Softening, Induration, and Atrophy of the Cord—Concussion of the Spine—Paralysis... 142 XVI. Diseases of the Neryofs System (continued). Epilepsy—Tetanus 151 XVII. Diseases of the Neryofs System (continued). Chorea — Catalepsy — Hysteria — Neuralgia — Local Spasms 161 XVIII. Diseases of the Eye. Inflammation of the Lids—Spasmodic and Para- lytic Affections of the Lids—Tarsal Tumours —Inflammation of the Lachrymal Sac—Fistula lachrymalis— Conjunctivitis simplex—Oph- thalmia neonatorum—Gonorrhoeal Ophthal- mia — Purulent Ophthalmia — Diphtheritic conjunctivitis 175 XIX. Diseases of the Eye (continued). Strumous Ophthalmia—Rheumatic Ophthalmia —Arthritic Ophthalmia—Syphilitic Ophthal- mia 185 XX. Diseases of the Eye (continued). Pterygium— Corneitis— Corneal Opacities—Iritis —Mydriasis— Choroiditis— Cataract—Glau- coma — Retinitis—Amaurosis—Asthenopia— Hemeralopia—Diplopia—Myopia and Pres- byopia—Photophobia—Photopsia and Chro- matopsia—Strabismus 192 XXI. Diseases of the Ear. Frysipelas aurium — Eczema aurium — Otitis externa— Otorrhoea—Polypus aurium—Exos- toses of the Meatus — Inflammation of the Membrana Tympani — Throat Deafness — Otalgia — Inflammation, Hypertrophy, and Rigidity of the Tympanic Mucous Membrane— Anchylosis of the Tympanic Ossicles—Caries of the Mastoid Process—Nervous Deafness— Tinnitus aurium 204 XXII. Diseases of the Digestive Organs. Ulcers of the Mouth—Cancer of the Lips— Glossitis—Ulcers, Syphilis, and Cancer of the Tongue — Odontalgia —Parulis —Ptyalism— Parotitis 216 XXIII. Diseases of the Digestive Organs (continued). Angina— Tonsillitis— Chronic Angina—Diph- theria 223 CONTENTS. CONTENTS IX Letter page XXIV. Diseases op the Digestive Organs (continued). Gastritis— XJlcer of Stomach—Cancer of Stomach —Gastrodynia 236 XXY. Diseases of the Digestive Organs (continued). Acute Dyspepsia — Chronic Dyspepsia — Pain after Food —Aridity — Heartburn— Water- brash—Flatulence— Vomiting—Hcematemesis 245 XXVI. Diseases of the Digestive Organs (continued). Inflammation and Spasmodic Stricture of the (Esophagus— Enteritis—Intestinal Ulceration, Cancer, and Haemorrhage—Enterodynia 255 XXVII. Diseases of the Digestive Organs (continued). Diarrhoea—Dysentery—Cholera 261 XXVIII. Diseases of the Digestive Organs (continued). Constipation—Intestinal Obstruction—Hernia . 272 XXIX. Diseases of the Digestive Organs (continued). Haemorrhoids—Fissure of Anus—Prolapsus ani Fistula in ano—Worms — Peritonitis — Ascites 279 XXX. Diseases of the Digestive Organs (continued). Diseases of the Pancreas—Hepatic Congestion— Hepatitis Cirrhosis of the Diver — Acute Atrophy—Fatty, Amyloid, Pigmentary, and Cancerous Degeneration of the Liver—Jaun- dice— Gall-stones 289 XXXI. Diseases of the Respiratory Organs. Nasitis — Coryza — Influenza — Hay fever — Ozaena—Epistaxis—Polypus narium—Laryn- gitis—Aphonia 297 XXXII. Diseases of the Respiratory Organs (con- tinued). Bronchitis — Dilatation of the Bronchi — Em- physema—Asthma 306 XXXIII. Diseases of the Respiratory Organs (con- tinued). Pneumonia—Pulmonary Abscess and Congestion Hcemoptysis — Pulmonary Apoplexy — (Edema Pulmonum 316 XXXIV. Diseases of the Respiratory Organs (con- tinued). Phthisis Pulmonalis—Pulmonary Syphilis and Cancer 323 XXXV. Diseases of the Respiratory Organs (con- tinued). P leurisy — Hydrothorax — Empyema—Pneumo- thorax—Pleurodynia—Injuries of the Chest... 330 X Letter page XXXVI. Diseases op tee Circulatory System. Diseases of the Heart: Palpitation, Hyper- trophy, Dilatation, Patty Degeneration—Angina Pectoris—Pericarditis — Endocarditis —Chronic Valvular Disease 338 XXXVII. Diseases of tiie Circulatory System (con- tinued). Arteritis, Aneurism, and Atheroma — Phlebitis and Varicosis—Pyaemia—Angioleucitis—Inflam- mation and Hypertrophy of the Spleen—Leuco- cythcemia—Disease of the Supra-renal Capsules— Bronchocele—Exophthalmic Goitre 346 XXXIX. Diseases of the Urinary Organs. Albuminuria, from—Nephritis—Granular Dege- neration—Amyloid Degeneration—Patty De- generation—and other causes 355 XL. Diseases of the Urinary Organs (continued). Albuminuria—Chylous Urine —Diabetes —Poly- uria—Gravel—Azoturia 368 XLI. Diseases of the Urinary Organs (continued). Penal Congestion—Suppression of Urine—Hcema- turia—Pyelitis—Penal Cancer and Tubercle— Cystitis—Irritable Bladder—Strangury—Reten- tion of Urine—Stone—Cancer of the Bladder— Stricture of the Urethra 378 XLII. Diseases of the Male Sexual Organs. Orchitis —Sarcocele—Irritable Testicle—Neural- gia Testis—Impotency— Sterility— Spermator- rhoea — Hydrocele — Varicocele—Petraction of the Testicles—Prostatitis—Gonorrhoea—Balani- tis—Soft Chancre—Epithelioma of Penis and Scrotum—Inflammation of Scrotum 387 XLIII. Diseases of the Female Sexual System. Ovaritis—Ovarian Neuralgia—Ovarian Dropsy ■—Menorrhagia—Amenorrhoea — Chlorosis — In- frequent and Vicarious Menstruation—Dysme- norrhcea 399 XLIV. Diseases of the Female Sexual System (con. tinued). Uterine Congestion —Hysteralgia — Endo-metritis — Cervico-metritis — Leucorrhoea — Peri-uterine Hcematocele— Uterine Displacement—Polypus— Fibrous Tumour—Cancel—Hydrometra 411 CONTENTS. CONTENTS. XI Lettee page XLV. Diseases op the Female Sexual System (con- tinued). Vaginitis — Vaginismus — Vulvitis—Acute Labial Abscess—Pudendal Cancer—Pruritus Pudendi— Nymphomania—Vascular Tumour of the Urethra —Sterility—Chronic Mammary Tumour—Irri- table Tumour of the Breast—Mammary Scirrhus 424 XLYI. Diseases op the Female Sexual System (con- tinued). Disorders of Pregnancy: Mental Disorder, Head- ache, Sleeplessness, Tooth-ache, Salivation, Vomit- ing, Heartburn, Cravings, Constipation, Diar- rhoea, Cough, Dyspnoea, Irritation of Bladder, Albuminuria, Uterine pain, Mammary pain, Lumbar pain, Pruritus, False pains—Miscarriage 431 XLV1I. Diseases op the Female Sexual System (con- tinued). Disorders of Parturition: Mal-presentation, Rigid os uteri, Deficient pains, Excessive pains, Retained Placenta—Post-partum Hcemorrhage— Puerperal Convulsions 440 XLVIII. Diseases of the Female Sexual Organs (con- tinued). Disorders of the Puerperal State: After-pains, Torn Perinceum, Retention of Urine, Hcemor- rhoids, Morbid Lochia, Constipation, Diarrhoea— Puerperal Fever—Puerperal Insanity—Disorders of Lactation: Milk Fever, Deficient Milk, Painf ul Suckling, Weaning, Over-lactation, Mastitis— Phlegmasia alba dolens—Critical Age 448 XLIX. Diseases of the Skin. Erythema — Erysipelas — Urticaria —'Roseola — Eczema —Herpes— Scabies—Pemphigus—Rupia —Impetigo—Ecthyma—Lichen—Prurigo—Pity- riasis — Psoriasis — Lepra —Lupus—Elephan- tiasis 458 L. Diseases of the Skin (continued). Warts — Molluscum — Acne — Sycosis menti — Alopecia—Plica Polonica — Favus—Furuncle— Carbuncle—Whitloiv—Disease of Nail Matrix — Ulcers—Pruritus 467 LI. Diseases of the Locomotiye Organs. Myositis —Myalgia — Cramps —Muscular Rheu- matism—Periostitis —Nodes—Ostitis— Caries— Necrosis—Neuralgia of Bone—Mollities Ossium — Synovitis — White Swelling — Arthralgia— Bursitis—Ganglion 475 XII CONTENTS. Letter page LII. Diseases op Children. Rachitis—Remittent Fever—Hereditary Syphilis —Acute Hydrocephalus—Chronic Hydrocepha- lus— Convulsions—Infantile Paralysis 486 L1II. Diseases of Children (continued). Stomatitis —Aphthae—Cancrum Oris —Stammer- ing—Morbid Dentition—Diarrhoea— Co lie—Pro- lapsus Ani—Tubercular Peritonitis 496 LIV. Diseases of Children (continued). Laryngismus Stridulus — Pertussis — Croup — Proncho-pneumonia 505 LY. Diseases of Children (continued). Strumous Adenitis—Tabes Mesenterica—Fnuresis nocturna and other Urinary Difficulties—Leu- corrhaea —Noma Pudendi —Intertrigo—Crusta Lactea —Porrigo Capitis —Strophulus —Ring- worm — Cephalhcematoma — Neevus — Hernia— Mastitis—Icterus—Scleroderma—Trismus 515 LVI. Casualties—Miscellaneous. Wounds—Contusions—Strains—Rums and Scalds — Chilblains —Stings —Fractures —Sunstroke— Fmotional Disturbances—Atrophy —Gangrcena Senilis—Conclusion 523 LETTER I. INTRODUCTORY My dear It is now some time since I wrote you my last letter on Pharmacodynamics. In its concluding sentences I promised ere long to enter with you upon Therapeutics,—to tell you what Homoeopathy can do for the manifold forms of disease, and how it does it. That it is necessary I should thus take up the subject from the side of disease, you have already found in working with my former letters. You have wished that I had affixed to them a clinical index, noting against the various maladies of the human frame the medicines I had mentioned as useful in their treatment. Indeed, you have se- riously thought about compiling some such index for your own use, did I not speedily provide you with a fuller guide to practice. I will therefore delay no longer to redeem my promise: and will begin at once to write you a series of letters on Therapeutics. Let us distinctly understand what it is I propose to do for you in the following letters. You do not want me to write you a treatise on the Practice of Physic. You know disease as well as I do. I can 1 2 INTRODUCTORY. tell you nothing about the history, the diagnosis, or the pathology of its various forms but what you know already, or at any rate may acquaint yourself with by consulting the authorities on your book- shelves. You will meet me half-way here: and I may spare myself the travel over the familiar road. What you want to know is this. Here is a recog- nised malady. You have been accustomed to treat it in such and such a way, and with such and such success. Has Homoeopathy discovered how to treat it better? How far shall you be justified in any given case in dispensing with measures which, how- ever rude, are tried, and trusting unreservedly to the action of specific medicines? The question is a fair, and indeed an imperative one for you to put. The law of similars, relating as it does solely to the dynamic action of medicines, has obviously limitations inherent in its own nature. It is farther only capable of application to practice when similarly acting medicines have been disco- vered. There may be diseases therefore which lie beyond its possible range. Still more likely is it that there are diseases which have not yet come within its practical range. Accordingly, our first step must be to inquire what Homoeopathy can do—as compared with the capabilities of Old Physic—in each malady that comes before us. And next you will require to know what are the specific remedies with which success has hitherto been obtained : and how far they need supplement- ing by auxiliary means. To answer these questions, from a survey of Homoeopathic literature and from my own expe- INTRODUCTORY. 3 rience, will be my only and sufficient task. I shall say no more upon the nature of the various diseases than is necessary for their identification, that we may know we are thinking of the same thing. Confining ourselves thus to their prognosis and treatment, we shall save an infinity of time and space : and shall be devoting our energies to what are really the only points on which your adop- tion of Homoeopathy requires you to have fresh knowledge and modified views. In executing such a work, moreover, I shall be doing something for you which you will not find in any volume now extant. The few manuals of general therapeutics which the Homoeopathic school has produced are framed upon a much more ambi- tious scale. They aim at being complete Treatises on the Practice of Medicine, and at superseding, for Homoeopathic students and practitioners, the ordinary text-books. Shall I confess that this “ vaulting ambition” of theirs seems to me to “ overleap itself And fall on the other side” ? Can they describe like Watson, or compile like Aitken ? I have not seen the recent works of Bahr and Kafka : but I have before me Laurie’s “ Elements of the Homoeopathic Practice of Phy- sic,” Hartmann’s “ Acute and Chronic Diseases and their Homoeopathic Treatment,” and Marcy and Hunt’s “ Homoeopathic Theory and Practice of Medicine.” Dr. Laurie’s book was probably useful once : but it is imperfect in the extreme. It omits numerous forms of disease: and in recommending 4 INTRODUCTORY. medicines rarely tells us whether the choice is made on a priori considerations, or from actual expe- rience. Hartmann, garrulous, credulous, yet prac- tical, is out of date;—his pathology is obsolete, and his nomenclature barely intelligible. Of Drs. Marcy and Hunt’s attempt I have spoken at large in vol. xxiii of the ‘ Brit. Journ. of Horn.,’ p. 475. I regret that I cannot recommend a work which must have cost its authors so much pains. The truly valuable therapeutical literature of our school consists in the clinical records scattered throughout its periodicals, or brought together in the collections of Riickert and Beauvais (Roth): and in the monographs we have on special forms of disease. To these I shall make copious reference as I go on. I shall also occasionally mention the text-books, when their treatment of any subject is instructive. My letters will thus serve as an index to our therapeutic literature at large : so that under its guidance you will be enabled to read up the most that has been written on any malady which is demanding your special attention. In making a classification of diseases for my purpose, I have not aimed at any striking novelty. Before the appearance of Dr. Russell Reynolds’ “ System of Medicine” I had already adopted his division of maladies into “ General” and “ Special.” I have ventured, however, to call the general dis- eases “blood-diseases”—grouping them accordingly; and have omitted from their number all which more obviously belong to the disorders of particular organs. Such are mumps, diarrhoea, dysentery, and cholera,—which I place among the diseases of INTRODUCTORY. 5 the alimentary canal and its associated glands : and influenza and hooping-cough, which I relegate to the sphere of respiratory disorders. I have also introduced the diseases of certain organs,—as the eyes, ears, bones, and joints,—which are usually supposed to belong to Surgery, but to which Ho- moeopathic Medicine has much to say. The result has been the following grouping, which will at least be practical and intelligible, and which I think omits no morbid state of importance. I. BLOOD DISEASES. Plethora. Anemia. Scurvy. Purpura. Scrofulosis. Tuberculosis. Cancer. Gout. Rheumatism. Rheumatic Gout. Gonorrhceal Rheumatism. Febricula. Typhus. Typhoid. Relapsing Fever. Yellow Fever. Plague. Epidemic Cerebro-spinal Meningitis. Ague. Remittent Fever. Variola. Varicella. Measles. Scarlatina. Rotheln. Dengue. Miliaria. Hydrophobia. Glanders. Malignant Pustule. Syphilis. Sycosis. II. DISEASES OF THE NERVOUS SYSTEM. Diseases op the Head. Meningitis. Phrenitis. Softening. Apoplexy. Mania. Melancholia. Dementia. Idiocy. General Paralysis of the Insane. Hypochondriasis. 6 INTRODUCTORY. Diseases of the Head—con- tinued. Delirium Tremens. Headache. Vertigo. Insomnia. Injuries of the Head. Diseases of the Spinal Cord. Meningitis. Myelitis. Congestion. Irritation. Haemorrhage. Softening. Induration. Atrophy. Concussion. Paralysis. The Neuroses. Epilepsy. Tetanus. Chorea. Catalepsy. Hysteria. Eeuralgia. Local Spasms. Diseases of the Lids. Inflammation of the Eye- lids. Spasmodic and Paralytic Affections of the Eye- lids. Tarsal Tumours. Diseases of the Lachrymal Apparatus. Inflammation of the Lach- rymal Sac. Fistula lachrymalis. The Ophthalmia. Conjunctivitis simplex. Ophthalmia neonatorum. Gonorrhoeal Ophthalmia. Purulent Ophthalmia. Diphtheritic Conjunctivi- tis. Strumous Ophthalmia. Rheumatic Ophthalmia. Arthritic Ophthalmia. Syphilitic Ophthalmia. III. DISEASES OF THE EYE. Diseases of the Conjunctiva. Pterygium. Diseases of the Cornea. Corneitis. Opacities. Diseases of the Iris. Iritis. ♦ Mydriasis. Diseases of the Choroid. Choroiditis. Diseases of the Lens. Cataract. Diseases of the Vitreous. Glaucoma. Diseases of the Retina. Retinitis. Amaurosis. Asthenopia. Hemeralopia. Diplopia. Myopia. Presbyopia. Photophobia. 7 Diseases of the Retina— continued. Photopsia. Chromatopsia. INTRODUCTORY. Diseases of the Oculab Mus- cles. Strabismus. IV. DISEASES OF THE EAR. Diseases of the Extebnal Eae. Erysipelas aurium. Eczema aurium. Diseases of the Extebnal Meatus. Otitis externa. Otorrhoea. Polypus. Exostosis. Diseases of the Membbana Tympani. Inflammation. Diseases of the Eustachian Tube. Throat-deafness. Diseases of the Tympanum. Otalgia. Inflammation of Mucous Membrane. Hypertrophy and Rigidity of ditto. Anchylosis of Ossicles. Diseases of the Mastoid Cells. Caries. Diseases of the Inteenal Eae. Nervous Deafness. Tinnitus Aurium. V. DISEASES OF THE DIGESTIVE ORGANS. Diseases of the Theoat. Angina. Tonsillitis. Chronic Angina. Diphtheria. Diseases of the (Esophagus. Inflammation. Spasmodic Stricture. Diseases of the Stomach. Gastritis. Dicer. Cancer. Gastrodynia. Acute Dyspepsia. Chronic Dyspepsia. Diseases of the Mouth. Ulcers of the Mouth. Cancer of the Lips. Diseases of the Tongue. Glossitis. Ulcers. Syphilis. Cancer. Diseases of the Teeth. Odontalgia. Parulis. Diseases of the Salivaby Glands. Ptyalism. Parotitis. 8 INTRODUCTORY. Diseases of the Stomach— continued. Pain after food. Acidity. Heart-burn. Water-brash. Flatulence. Vomiting. Hcematemesis. Diseases of the Intestines. Enteritis. Ulceration. Cancer. Haemorrhage. Colic. Diarrhoea. Dysentery. Cholera. Constipation. Intestinal Obstruction. Hernia. Haemorrhoids. Fissure of Anus. Prolapsus Ani. Fistula in Ano. Worms. Diseases of the Peritoneum. Peritonitis. Ascites. Diseases of the Pancreas. Pancreatitis. Cancer. Diseases of the Liter. Congestion. Hepatitis. Acute Atrophy. Cirrhosis. Fatty Degeneration. Amyloid Degeneration. Pigmentary Degeneration. Cancer. Jaundice. Oall-stones. VI. DISEASES OF THE RESPIRATORY ORGANS. Nasitis. Coryza. Influenza. Hay fever. Ozaena. Epistaxis. Polypus Narium. Laryngitis. Aphonia. Pronchitis. Bronchiectasis. Emphysema. Asthma. Pneumonia. Abscess of Lung. Pulmonary Congestion. Haemoptysis. Pulmonary Apoplexy. (Edema Pulmonum. Phthisis Pulmonalis. Pulmonary Syphilis. Pulmonary Cancer. Pleurisy. Hydrothorax. Empyema. Pneumo-thorax. Pleurodynia. Injuries of the Chest. INTRODUCTORY. 9 VII. DISEASES OF THE CIRCULATORY SYSTEM. Diseases of the Heart. Palpitation. Hypertrophy. Dilatation. Fatty Degeneration. Angina Pectoris. Pericarditis. Endocarditis. Chronic Valvular Disease. Diseases of the Blood-ves- sels. Arteritis. Aneurism. Atheroma. Phlebitis. Varicosis. Pyaemia. Diseases of the Absorbents. Angioleucitis. Diseases of the Spleen. Splenitis. Hypertrophy. Leucocythcemia. Diseases of the Supra-renal Capsules. Addison’s Disease. Diseases of the Thyroid Gland. Bronchocele. Exophthalmic Goitre. VIII. DISEASES OF THE URINARY ORGANS. Diseases of the Kidney. Nephritis. Granular Degeneration. Amyloid Degeneration. Fatty Degeneration. Albuminuria. Chylous Urine. Diabetes. Polyuria. Gravel. Azoturia. Congestion. Ischuria. Hcematuria. Pyelitis. Cancer. Tubercle. Diseases of the Bladder. Cystitis. Irritable Bladder. Strangury. Retention of Urine. Stone. Cancer. Diseases of the Ubethka. Stricture. IX. DISEASES OF THE MALE SEXUAL ORGANS. Diseases of the Testis. Orchitis. Sarcocele. Irritable Testicle. Neuralgia Testis. Impotency. Sterility. Spermatorrhoea. 10 INTKODUCTOIIY. Diseases of the Testis—con- tinued. Hydrocele. Diseases of the Spermatic Cord. Varicocele. Detraction of the Testicles. Diseases of the Prostate Gland. Prostatitis. Diseases of the Penis and Scrotum. Gonorrhoea. Balanitis. Soft Chancre. Fpithelioma. Inflammation of the Scro- tum. Diseases of the Ovaries. Ovaritis. Neuralgia. Dropsy. Disorders of Menstruation. Menorrhagia. Amenorrhcea. Chlorosis. Inf requent Menstruation. Vicarious Menstruation. Dysmenorrhoea. Diseases of the Uterus. Congestion. Hysteralgia. Undo-metritis. Cervico-metritis. Leucorrhoea. Peri-uterine Hcematocele. Displacements. Polypus. Fibrous Tumour. Cancer. Hydrometra. Diseases of the Vagina and Pudenda. Vaginitis. X. DISEASES OF THE FEMALE SEXUAL SYSTEM. Vaginismus. Vulvitis. Acute Labial Abscess. Cancer. Pruritus. Nymphomania. Vascular Tumour of Ure- thra. Sterility. Diseases of the Mammj;. Chronic Tumour. Irritable Tumour. Scirrhus. Disorders of Pregnancy. Miscarriage. Disorders of Parturition. Post-partum Hemorrhage. Puerperal Convulsions. Disorders of the Puerperal State. Puerperal Fever. Puerperal Insanity. Disorders of Lactation. Phlegmasia alba dolens. Critical Age. INTRODUCTORY. 11 XI. DISEASES OF THE SKIN. Exanthemata. Erythema. Erysipelas. Urticaria. Roseola. VESICULE. Eczema Herpes. Scabies. Pemphigus. Rupia. PUSTULE. Impetigo. Ecthyma. PAPULE. Lichen. Prurigo. Squame. Pityriasis. Psoriasis. Lepra. Tubercule. Lupus. Cheloid. Elephantiasis. Diseases of the Papilla. Icthyosis. Warts. Diseases of the Sebaceous Glands. Molluscum. Acne. Sycosis menti. Diseases of the Hair Fol- licles. Alopecia. Plica Polonica. Favus. Mis cellaneous. Furuncle. Carbuncle. Whitlow. Diseases of the Nail-ma- trix. Ulcers. Pruritus. XII. DISEASES OF THE LOCOMOTIVE OKGANS. Diseases of the Muscles. Myositis. Myalgia. Cramps. Muscular Rheumatism. Diseases of the Bones. Periostitis. Nodes. Ostitis. Caries. Necrosis. Neuralgia. Mollifies Ossium. Diseases of the Joints. Synovitis. White Swelling. Arthralgia. Eursitis. Ganglion. 12 INTRODUCTORY. XIII. DISEASES OF CHILDREN. Blood Diseases. Rachitis. Hereditary Syphilis. Infantile Remittent Fever. Diseases of the Neetous System. Acute Hydrocephalus. Chronic Hydrocephalus. Convulsions. Infantile Paralysis. Diseases of the Digestive Oegans. Stomatitis. Aphthae. Cancrum Oris. Stammering. Morbid Dentition. Diarrhoea. Colic. Prolapsus Ani. Tubercular Peritonitis. Diseases of the Respieatoey Oegans. Laryngismus Stridulus. Pertussis. Croup. Broncho-pneumonia. Diseases oe the Cibculatoey System. Strumous Adenitis. Tabes Mesenterica. Diseases of the Ubinaby Oegans. Enuresis Nocturna. Diseases of the Genital Oegans. Noma Budendi. Diseases of the Skin. Intertrigo. Crusta Lactea. Porrigo Capitis. Strophulus. Ringworm. Miscellaneous. Cephalhcematoma. Ncevus. Hernia. Mastitis Neonatorum. Icterus Neonatorum. Scleroderma Neonatorum. Trismus Neonatorum. XIV. CASUALTIES. Wounds. Contusions. Strains. Burns and Scalds. Chilblain. Stings. Fractures. Sun-stroke. Emotional Disturbances. XV. MISCELLANEOUS. Atrophy. Oangrcena Senilis. LETTER II. “ SIMILIA SIMILIBUS.” Before entering upon the main subject of the present volume, viz. the Homoeopathic treatment of the various forms of disease, there are several pre- liminary questions on which we must come to an understanding. The chief of these is, What is Homoeopathy ?—wherein does it essentially consist ? what does it include and what exclude? and what are your duties and limitations now that you are avowedly practising under its banner ? To the consideration of this group of questions I shall devote the present letter. Homoeopathy is, pi'imd facie, the treatment of disease by medicines selected according to the rule “ similia similibus curentur ” “ let likes be treated by likes.”* The “like” (o/uoiov) here spoken of is explained by Hahnemann as opposed both to the “ different ” (aAAotov) and to the “ contrary ” (Ivavriov). Thus :—a case of disease is before us. * I prefer this putting of the motto—which is indeed Hahne- mann’s original formula—to the affirmation “similia sitnilibus curawtur” usually adopted at the present time. I have no desire to quarrel with the Latinity of the latter : though the use of “euro” in the sense of “ cure” is at least unfamiliar. But in the present state of our knowledge I think it wiser to state our principle as a rule of Art than as a law of Science. 14 “similia similibus.” We are not to consider what processes of evacua- tion, revulsion, and such like, will benefit, and pre- scribe our remedies accordingly. Nor are we to think what drug will act in an opposite direction to the symptoms present, and accordingly give Strych- nia for paralysis, aud Opium for sleeplessness. Our inquiry should rather be—what drug is capable of producing upon the healthy body a morbid condition similar to the one before us? The presence of sleeplessness will suggest a medicine capable of banishing natural sleep, as Coffee: while Opium will be indicated rather in conditions of sopor— as in fevers—similar to that which it commonly induces. But now of this “similarity” itself the question arises, wherein does it consist ? This is a point which has exercised the minds of our best men from Hahnemann downwards. For the opinions of the master and his early disciples I refer you to Dr. Dudgeon's “Lectures on Homoeopathy.” Later deliverances on the subject are the essays “ On the Various Actions of Medicines” and on “ Contraria Contrariis” by Dr. Madden in the 8th and 25th vols. of the ‘British Journal of Homoeopathy,’ on “ the Homoeopathic and Allopathic Use of Specifics ” by Dr. Drysdale in vols. xxiv—xxvi, on “ Similia Similibus Curantur” by Dr. Elb in vol. xxvi, and on “ Organopathy ” and “ The Anatomical Basis of Therapeutics’’ by Dr. Sharp in the ‘Monthly Homoeopathic Review ’ for 1867—8. To these I must add Dr.Carroll Dunham’s treatise on “Homoeo- pathy the Science of Therapeutics.” You will do well at your leisure to read what these able thinkers “ SIMILIA STMILIBUS.” 15 have taken the pains to set down upon the point before us. For the present I shall endeavour to express what I myself understand by our thera- peutic rule, and by the “ similarity ” of which it speaks. For this “ similarity,” then, I take the first requisite to be that it be real and not merely apparent. It will not do, because a medicine has caused a sense of weakness and weariness in the lower extremities, to set it down as homoeopathic to paraplegia. When the prover of a drug has expe- rienced from its action a cough with stitchings in the side, he must not infer that he has found the simile of pleurisy or pneumonia. However nume- rous the varieties of diseases thus named, however unique in some respects each individual instance of their occurrence, there are in all certain essential elements, certain peculiar pathological changes. That a medicine shall be capable of causing these changes on the healthy body is the primary requi- site to its homoeopathic relationship. Now how is it to be ascertained that this essen- tial similarity between disease and drug exists? Hahnemann answers, by finding that the “ totality of symptoms” in each coincide. Exception has been taken to his statement; but I imagine that it is based on some misconception of what he means by “ symptoms.” He could not wish to limit the term to those phenomena which appear on the surface, and strike the uneducated eye. At any rate, that is not what we mean by symptoms now. We know that very often the same surface symptom belongs to two or more utterly distinct conditions of the 16 “ SJMTLIA SIMILIBUS.” body, while the symptoms which distinguish these conditions do not lie on the surface, and can only be ascertained by more profound research. They are still symptoms; for every disease is only a group of symptoms or appearances. But they need the pathologist to discover them ; bringing as he does to his aid all the resources of science (the stethoscope, the microscope, the speculum, the test- tube), and thus seeing not only all that the others see on the surface, but all that lies beneath the sur- face as well; so that he can distinguish where they could not, and the ojuoiov to them would be the aXXoTov to him. In Hahnemann’s day, indeed, pathology could hardly be said to exist as a science. But his doctrine is the same. Obtain all the symp- toms you possibly can, both in proving your medi- cines and in examining your patients; then, in prescribing for an individual case, select that remedy which corresponds most nearly to the totality of the symptoms present. The symptoms, then, on whose presence the com- parison of disease and drug is to be effected, are all that can be ascertained, both subjective and objec- tive, both surface and deep. If all which constitute the disease are to be found in their due proportion and sequence in the pathogenesis of the drug, the similarity we desiderate must be considered to be established. Such a simile is Strychnia to tetanus, Cannabis Indica to catalepsy, and Hydrocyanic Acid to the epileptic paroxysm. It cannot be objected with justice that from such a comparison diagnosis is excluded. If diagnosis means the perception of the precise seat of the malady, and of the exact “ SIMILIA SIMILIBUS.” 17 morbid alteration which is going on therein, then it is indeed often necessarily excluded, whether as regards disease or as regards drug-action. Who will tell us what Catalepsy is? Yet it is a definite condition, and the Indian hemp has been observed to produce it. But diagnosis more properly means the clistinguishment of one form of disease from all others which resemble it: and the very means of effecting such distinguishment is a consideration of what symptoms are present and what absent. Nor should it be affirmed that such a method of finding the simile makes the prescriber “liable to overlook the distinction between idiopathic and sym- pathetic affections; between symptoms which arise from diseases of the organs they are connected with, and those which are the effect of sympathy with some other diseased organ.”* Such a mistake would be due to his own ignorance or carelessness,— not to any fault in his method. How do we dia- gnose between vomiting of cerebral and of gastric origin except by considering all the symptoms pre- sent, and observing their proportion and sequence ? If we have done the same with our drug-symptoms, we are not likely to select “ inappropriate remedies” in any given case. A signal merit in this method of arriving at the true simile is that it ensures that the likeness shall be specific, and not merely generic. All things are like each other in some points, but differ in others. All diseases are departures from health: but some are miasmatic, some diathetic, some “ dietic.” All the miasmatic diseases are febrile; but some of the * Dr. Sharp on * Organopathy.’ 18 “ SIMILIA SIMILIBUS.” fevers are intermittent, some continued, some erup- tive. Again, the eruptive fevers resemble each other in possessing an exanthem, but differ according as this is of the character of measles, scarlatina, or small-pox. Then there are certain well-recognised varieties of each of these diseases, in which the characters essential to each exist with certain dif- fering modifications or concomitants. Lastly, each individual case of either small-pox, measles, scarla- tina, or any other disease, has its own peculiarities which distinguish it from every other case. Now the method by totality of symptoms provides for this individualization, alike of disease and remedy. If fully followed out, the medicine will correspond with the malady, not only in the generic lesion we call pneumonia, phthisis, dysentery, and so on, but in the specific characters assumed by it in the variety we are observing, or in the individual patient before us. These specific differences cannot be accidental: they are parts of an organic whole. If they are not found in the medicine as well as in the disease, the former so far falls short of that perfect similarity which is required to ensure per- fect success. The method by totality of symptoms, moreover, has the advantage of meeting every conceivable case. It is only a portion of the great world of disease that has yet been so accurately surveyed that it can be mapped, and planned, and fitted with names. For such concrete maladies only can speci- fics be allotted beforehand. Beyond their range lies a terra incognita of derangements the most diverse, complex, and varying, which as yet defy “ SI MI LI A S1MILIBUS.,J> 19 classification and nomenclature. To cases of this kind the symptomatic method is the only one applicable. I knew not the significance of the occurrence, in a patient convalescing from parturi- tion, of urine loaded with lithates, debility, low spirits, anorexia, copious sour perspirations, and persistent aching of the mammae. But I found all these symptoms (save the last) in the patho- genesis of Causticum: and selected that remedy accordingly, with amply satisfactory results. Hitherto I have been vindicating the scientific accuracy and practical adaptability of the Ilalme- mannian method. Such vindication is necessary if we would not disown those early successes which made the fortune of Homoeopathy so rapidly. But as you read what I shall hereafter write to you, you will see that it is rare indeed that a complete paral- lelism of symptoms exists between diseases and their remedies. But few medicines have been exhaustively proved : and the form in which the early provings have been handed down to us renders any rational comparison of their symptoms with those of disease out of the question. You will find us led to the simile—sometimes by a mere hint in the patho- genesis, sometimes by the evidence of a post- mortem examination, sometimes by the usus in morbis reflecting light upon a group of symptoms otherwise meaningless, sometimes by that usus in morbis alone. But I would have you observe that, by whatever pathway reached, it is the true simile which is obtained. That is, we have found the medicine which is in specific relationship with the disease,—with the part affected, and with the 20 “ SIMILIA SIMILIBUS.” manner of its affection. Baptisia effects as defi- nite an extinguishment of gastric as does Aconite of simple fever: but the application of the former was obtained from merely empirical sources, while that of the other was a pure induction of Hahne- mann’s from the symptoms of his proving. Let me enlarge a little farther on this head. I have spoken of the necessity of considering the sequence of symptoms. This applies especially to those symptoms called “primary and secondary.” Thus, the initial chill and the subsequent burning heat of fever are apparently opposites; and it would seem that a medicine which would be homoeopathic to the rigor would be antipathic to the calor. But observation teaches us that the chill and the heat are but successive expressions of the same morbid condition: experiment even proves that the tem- perature is rising while the patient is still shivering. So far, then, from a different medicine being re- quired for the two stages, it is essential that the one medicine which shall control both shall be capable of causing both, as indeed Aconite does. It is the simile of the two series of phenomena because it is in specific relationship with the vas- cular nerves, and with that disorder of their regulating function in which simple fever consists. The same thing is true of what are known as “alternating symptoms.” We know Nux vomica as one of the remedies for constipation, and Mer- eurius for diarrhoea. But we find looseness of the bowels no rare symptom in the pathogenesis of the former, and constipation in that of the latter. If we are puzzled, observation of disease soon “ SIMILIA SIMILIBUS.” 21 explains the difficulty. That same irritable state of the intestinal fibre which in the adult induces constrictions which impede free evacuation, in in- fants leads to impatience and frequent emptying of the canal. While in chronic hepatic disorder it is no uncommon thing for the patient to complain that his bowels are sometimes unduly confined, and sometimes quite as deranged the other way. In alternating symptoms, then, as in those called primary and secondary, the relationship of simi- larity on the part of the medicine is with the underlying condition capable of producing either or both. Ilcnce “ contraria contrariis ” is often as true phenomenally as “ similia similibus,” and a no less certain guide to the right medicine. I do not mean to imply by this that mere antipathic power on the part of a drug qualifies it for a place among our remedies. Such means will sometimes meet tem- porary emergencies: but they have ever been found wanting in the treatment of prolonged and recurring disorders. Dr. Madden's Bromide of Potassium may have so quenched the acute erotic irritation of his patient that the sympathizing brain had time to recover from its mania. But the use of this drug in epilepsy, so much belauded at present, is to my mind a most unsatisfactory practice. By its dead- ening influence on the nervous centres it suspends the paroxysms for a while. But with its discon- tinuance they nearly always return ; and the patient must either live upon the drug all his lifetime, with evils yet untold developing under its use, or must takv. off the repressing influence only to see the 22 e< SIM ILIA SIMILIBUS.” fits returning, perhaps with renewed vigour after their temporary suspension. The adoption of the antipathic method, as such, is moreover rarely prac- ticable. Very few morbid states have any contraries. Can you tell me the opposite of gout or of scrofula, of typhus or of erysipelas? But the great bulk of the opposites are really not contrary but comple- mentary one to another. Spasm and paralysis, hyperesthesia and anesthesia, contraction and dila- tation of blood-vessels, sopor and insomnia, consti- pation and diarrhoea may succeed one another or replace one another or even co-exist in the same patient. They are but varying expressions of a sub-vital condition of an organ or of the general system,—the variation in the expression being governed by laws as yet little known to us. And so we arrive at the conclusion, that the true contrary of ofxoiog is not Ivavnog but dAAotoe, not opposite but foreign.* If a medicine have no spe- cific relationship to the part affected, Homoeopathic therapeutics have nothing to do with it. If it have such relationship, we shall not be deterred from giving it by an apparent contrariety between the symptoms induced by the drug and those present in our patient to-day. The opposite and comple- mentary symptoms may appear to-morrow. When- ever, indeed, as in tetanus or post-diphtheritic paralysis, in lead-colic or cholera, experience tells us that the symptoms set uniformly in one direction, it is necessary for the simile that the effects of the * Just as the true contrary of love is not hate, hut indifference. Love and hate both imply an interest in their object, and are often (in the lower grades of the former) interchangeable. “ SIM1LIA SIMILIBUS.” 23 medicine should point the same way. That is, the kind of affection, as well as the part affected, must coincide in the disease and the drug respectivel}r. This is still more important when we come to dis- criminate between the specifically different derange- ments which may affect the same organ. That a medicine acts on the liver, and sets up simple in- flammation therein, does not prove it homoeopathic to acute yellow atrophy. The tormina, tenesmus, muco-sanguineous stools, and post-mortem ulcer- ations of dysentery, must be reproduced in the pathogenesis, if a power of inflaming the mucous membrane of the large intestine is to constitute any drug a remedy for this disease. You will see, therefore, that I cannot coincide with Dr. Sharp’s revived “ Organopathy,” or adopt an exclusively “anatomical basis of therapeutics.” Specific re- lationship between drug and disease must include character as well as locality. But what I aim at showing is that specific relationship, thus under- stood, is the fundamental fact on which Homoe- opathic therapeutics are based. I believe, indeed, that in the Divine order of Nature there is a pre- established harmony between disease and drug- action,—between the idiopathic derangements of the organism and the action of poisons upon it: that there is no pathological condition, however peculiar or complex, which is not producible also by some drug, known or unknown. When every sub- stance in the mineral, vegetable, and animal king- doms capable of affecting the body shall have been proved upon it, and its full effects ascertained, then the ncaling art will not be far from perfection. In 24 “ SIMILIA SIMILIBUS.” the mean time mag is venenum magis remedium. The polychrests will be those which correspond to the greatest number and variety of morbid states, or to those of most frequent occurrence. The minor medicines will fill up gaps in those of wider range, or will occupy niches which, if left without special tenants, would be weak points in the therapeutic edifice. We return to our rule “ similia similibus curen- tur.” It appears now in the light of a guide-post towards the true object of our search, specific re- lationship. We may use it either a priori, as when we study the pathogenesis of a medicine to ascertain to what idiopathic diseases it is likely to correspond: or a posteriori, when in viewing a case we consider what medicine causes the group of symptoms we have before us% In either case the rule is our guide to the discovery of specifics. That they may be dis- covered in other ways is obvious. Sometimes, as I have mentioned, by the rule “ contraria contrariis curentur,” as when Ilyoscyamus was given for cere- bral excitement because it sometimes causes sopor. Sometimes purely empirically, “ by the merest chance,” as we say, of which Cinchona bark in ague is a notable instance. I only claim for the rule “ similia similibus” the first place as an instrument for this discovery :—its title thereto being that more specifics have been found by its means in the last fifty years than have rewarded other modes of re- search for the preceding five thousand. Aconite in simple fevers, Arsenic in those of a typhoid type, Belladonna in inflamed throat and erysipelas, Bryonia and Khus in rheumatism, Calcarea in the mal-assi- “ SIMIL1A SIMILIBUS.” 25 milative derangements of childhood, Camphor and Yeratrum in cholera, Chamomilla in nervous ere- thism, Coffea in sleeplessness, Colocynth in colic,— I could go on for a page enumerating the specifics already discovered by this potent instrument. That more and more will come to light as its materials increase, and its application becomes more sound and thorough, I firmly believe : until at last every possible variety of disease shall have found its suitable remedy. Then, and not till then, will Hahnemann's “ Novum Organon'5 cease to be necessary, for its work will have been accom- plished. This is the future of medicine to which I look. The “ perfecting of the Materia Medica” of which we so often hear I regard as only a means to an end; and in proportion as that end is attained the need of any Materia Medica.whatever becomes less and less. Few of us now ever consult the pathogeneses of Aconite or Belladonna, of Arsenic or Camphor. We know all their specific relationships : any fresh appli- cations they may yet receive will be only extensions of those already established. Pathology is every year pushing her outworks farther and farther on. The chaos of disease is steadily being brought into order, and its almost infinite varieties are being dis- tinguished and ticketed and classified. As each new species comes into light it will be our task to assign to it its specific remedy; and if more than one medi- cine corresponds to its symptoms, we must consider what are the varieties of the disease to which each belongs. We shall thus be building up the great 26 tc SIMILIA SIMILIBUS.” edifice of specific therapeutics of which the law of similars I take to be only the sqaffolding. To note, from time to time, the progress of this building, and to make suggestions for its best pos- sible extension ; to set down such specific treatment as has become classical, and to indicate the directions in which to look for more,—this is a work which needs to be done. The following pages, however feebly and imperfectly executed, will at least be wrought in this spirit and with this aim. If, be- sides helping yourself and others who may see them, they contribute anything, however humble, to our knowledge of true specific relationships, I shall not have toiled at them in vain. I have devoted so much space to the consi- deration of the meaning of our fundamental law, that I must defer to another letter the various ques- tions which arise as to its due application. LETTER III. THE DOSE AND ITS REPETITION CHANGE AND ALTER- NATION OF MEDICINES AUXILIARIES THE DUTIES OF THE HOMOEOPATHIC PHYSICIAN. } ou are now in the presence of a case of dis- ease. You are possessed, either through some pre- vious adaptation of remedy to malady, or from a comparison of your patient’s symptoms with the Materia Medica, of the similar medicine you require. But several questions have yet to be settled before you use it : and one of the first which will arise is that of the dose in which it is to be administered. You have probably already learnt that while all practitioners of our school are agreed upon the prin- ciples on which the remedy should be chosen, they are widely divided as to the quantity in which it should be given. It would be of little use for me to add my individual opinion to the multitude already existing. But you will have to make up your own mind upon the subject: and I can at least supply you with some of the data on which your judgment must be formed. The history of the “ homoeopathic dose” is as follows. When Hahnemann first began to pre- scrib' medicines according to the rule “ similia similibus,” he gave them in the usual quantities. 28 THE DOSE AND ITS REPETITION. It is not surprising that his patients* symptoms, even though ultimately removed, were often in the first instance severely aggravated. It needs no ar- gument to show that the ordinary doses of Arsenic, against which even a healthy stomach needs to be shielded, would increase the irritation of one already inflamed. So Hahnemann found, and he reduced his doses accordingly. At what stage of this re- duction he found that fractional quantities of a small- ness hitherto undreamt of exercised a potent influ- ence I cannot say. But once satisfied of the power of infinitesimals, he adopted them with enthusiasm as a part of the new system of medicine he was in- augurating. He regulated their preparation bv a fixed scale of dilution,—the centesimal. With this he boldly pushed on till at the 30tli dilution he had reached decillionths. Here he paused, and appears to have wished to draw at this point a “ hard and fast line/* In his ‘ Chronic Diseases* he recom- mends all medicines to be given in the 30tli dilu- tion, thus advancing to that point the many con- stituents of his £ Materia Medica Pura’ to which he had there assigned the I2th, 9th, or 3rd potency, or even the mother-tincture, as most suitable. With the exception of a suggestion in the preface to the proving of Thuja that such a drug might with advantage be raised even to the 60th, he seems himself to have kept to the 30th as an ultimatum. But his disciples were more Wilkesite than Wilkes himself. A few of them, amongst whom Trinks is eminent, declined even to follow the master, and used only the first two or three of the dilutions of his scale. But the more enthusiastic pushed on THE DOSE AND ITS REPETITION. 29 until the 200th had been reached, nor indeed paused there. You will find an account of the doings of these “ high-potency men” in Dudgeon's ‘ Lectures on Homoeopathy.' They have nearly died out in Germany, and have found very few representatives in France or England. But in America the school has taken a fresh start. 'With a number of prac- titioners there the 200th is considered a low potency, suited for common use : while the 1000th forms a new unit from which to start, and we hear of cures being wrought by the 71 iq dilution, which means the 71,000th ! I must leave you to satisfy yourself, if you care to do so, as to the claims made on behalf of these “ high potencies.” They are altogether outside the range of the Homoeopathy into which I am endeavour- ing to help your induction. I shall do more for you if I tell you how the dose question stands and has stood in this country, which is (with the exception above named) a fair representative of all others in this matter. The converts made to Homoeopathy in Great Britain seem to have started from about the level of the ‘ Materia Medica Pura.' The earliest practice on record in English literature exhibits the medium dilutions—the 12th to the 3rd—chiefly in use, the 30th also being pretty frequently administered. But a tendency soon displayed itself to descend rather than ascend the scale. The writings of Dr. Drysdale* and Dr. Maddenf and the cases recorded * ‘ Brit. Journ. of Horn.,’ vol. vi, p. 1. t Ibid., vol. xi, p. 1. 30 THE OOSE AND ITS HE PETITION. by Dr. Henderson* exhibit the march of this pro- gress. Now almost all British practitioners have joined it. A few remain behind, and protest loudly from their desolate eminences. But while some, and those not of least eminence among us, have even reached the mother tincture as the most suit- able dose, there are few of us who in our ordinary practice go above the 2nd and 3rd. There are indeed advocates for a more extensive range of dose, who believe that different medicines require to be given in very different dilutions, and that different dilutions of the same medicine often subserve very different purposes. Drs. Madden and Bayes are the chief defenders of this position in our present literature ; and with them I humbly range myself. But for your part you will do well to adopt as a general rule the dilutions from the 2nd to the 6th. When the evidence concurs and preponderates strongly, as in the case of Chamomilla, of Lachesis, of Lycopodium, in favour of the higher dilutions,—or as in that of Camphor, of Aconite, and of Baptisia on the side of the lower, you will feel bound to follow it. In other cases the range I have suggested will be found tolerably safe. I have carefully refrained from prejudicing you, either in these or in my former letters, on the ques- tion of dose. WTien writing to you upon our medicines, I have mentioned whether the higher or lower potencies have been most in favour, or whe- ther success has been claimed from different sides for both. In now discussing the treatment of dis- eases, I shall only name the potency of the medi- * * Brit. Joura. of Horn.,’ vols. viii, ix, &c. THE DOSE AND ITS REPETITION'. 31 eines I recommend when it is with the dose, as well as with the remedy, that the experience has gained. You will thus be put in a position to try, as all of us have had to try, the question for yourself; and the result at which you arrive will at least be your own, and not borrowed at second hand from another. For the bibliography of the dose question 1 refer you to Dr. Dudgeon's “ Lectures on Homoeopathy" (Lect. xiv, xv), and to the following papers in the ‘ British Journal of Homoeopathy.' Dr.Drysdale, “ Critical Examination of the Dose," vol. vi, p. 1. Dr. Black, “ Remarks on Posology,' vol. vii, p. 224. Dr. Madden, “ On Infinitesimals," vol. xi, p. 1. Ibid., “ A few more words about the Dose," vol. xix, p. 293. And in the ‘ Annals,' Dec. 1867, on “ The Dose,'’ by Mr. Edward T. Blake, with the Discussion. You will observe that with us the question of dose is that of the “ potency," not of the number of drops or grains. The latter is of little conse- quence, so far as quantity is concerned. But if there be anything in the principle of minute sub- division as extending a given quantity over a wider area,* and if it be so that a number of spermatozoa are requisite for the impregnating impulse, it would seem probable that several drops of the higher dilu- tions at least would make more impression than * See Doppler’s observations in he Essay of Dr. Samuel Brown in the “ Introduction to the Study of Homoeopathy ” by Drs. Drys- dale anu Bussell. 32 THE DOSE AND ITS REPETITION. one. I generally act upon this theory: but I have nothing positive to bring forward in the way of results. 2. You have now selected your medicine and determined upon its potency. The drops of tincture you prescribe will of course be mixed with water, and the grains of trituration suspended in the same vehicle or put dry upon the tongue. The next question which will arise will be as to the fre- quency of the repetition of the dose. It is strange that there should be any difference of opinion on this subject. You will almost instinctively do what the great mass of our practitioners do; i. e. give the medicine once or twice a day in chronic diseases, and in acute diseases from every four hours to every fifteen minutes according to the rapidity of the morbid process you are combating. But you will find that while the latter practice is almost universal, and in cholera at any rate received the sanction of Hahnemann himself, it is otherwise with chronic diseases. The master and his immediate disciples, and in the present day those among us who call themselves specially by his name, advocate in such cases the plan of giving one dose, and “ allowing it to act” for a length of time. A certain “ duration of action” is assigned in the ‘ Materia MedicaPura* and the ‘ Chronic Diseases* (on what grounds I know not) to each medicine : and the practitioner is considered impatient if within this period he repeats his dose. Twenty-four hours is the shortest of these durations : and a week, thirty, forty, fifty days are not uncommon. Now I am not going to condemn such a mode of CHANGE OF MEDICINES. 33 practice out of hand. On the contrary, I think it worthy of investigation. But I must assert that it has yet to he established upon experimental grounds. There is no evidence for the long duration ascribed to the action of certain medicines. There is a dif- ference among the Hahnemannians themselves as to whether the high or the low dilutions act the longest. Prof. Hoppe has argued the subject very ably from their point of view in the ‘ Brit. Journ. of Horn./ vol. xx, p. 269. But while we may grant him that in recent disturbance of the organ- ism a single medicinal impression may rectify the disordered balance, and set going the processes which lead back to health, it seems more likely that in disease of some standing a steady and regular repetition of such impressions at not too long intervals would effect most good. At any rate cures are frequently wrought in this way; so that if the repetitions are needless, they are harmless. I recommend you, therefore, for your own part, to follow the ordinary mode of proceeding. But it is right that you should be aware of the existence of this doctrine and practice; and I see no reason why you should not test it in cases where you really know something of the length of action of the medicine, and can watch closely the patient’s symptoms. 3. And now as to continuing your medicine. Are you to expect, when you have once chosen the simillimum of your patient’s condition, that he will be cured by that one remedy alone ? That he should be so cured is perhaps the ideal and the ulti- mate goal of the Homoeopathic method. But it is 34 CHANGE OF MEDICINES. certainly not practicable at present. In chronic disease, even though the starting-point should have been in one organ, by degrees other organs have become involved, and probably the blood and ner- vous system have deviated from the healthy stan- dard. A number of elementary morbid states are concurring to make up the concrete disease before us; and it is by no means certain that, even if you can discover the primary lesion, you can destroy the branches by your cuttings at their root. Very often, too, (the tendency of modern pathology is to say nearly always*) the disorder has begun in the system at large before it has localised itself in any particular organ. Hence your treatment of chronic disease must generally be the unravelling of the coils of a complicated knot, and you will require more than one medicine in its course. Carefully review your patient’s symptoms from time to time, and if any improvement which has resulted from his present medicine has come to a pause, consider whether any other seems more suitable. Only do not be too ready to make a change. Keep the ideal before you, even though at present it be un- attainable. You may sometimes, if the symptoms still point to the original remedy, change its potency only, ascending from low to high, or (still better, as I think) descending from high to low. The medicines to which your first study of the case, if a thorough one, conducted you should be adhered to as firmly as possible throughout its treatment. * See Dr. Gull’s * Address on Medicine/ before tlie British Medical Association, 1868, and the last Edition of Aitken’s ‘ Science and Practice of Medicine/ passim. CHANGE OF MEDICINES. 35 In acute disease we may approach more nearly to the standard. In many cases we are able to oppose the whole group of symptoms with one medi- cine, and see them melt away under its sole influ- ence. The number of diseases which admit of being thus dealt with is continually increasing : and they form some of the most satisfactory parts of our practice. Nor are all the exceptions truly such. For instance, when diseases have well-marked stages—as meningitis, typhoid fever, hooping-cough —it is no departure from the specific ideal to have a different medicine allotted to each stage. And the conformity is complete when the medicines for the different stages show a power of curing the disease then and there before it goes any farther. So, for instance,—while pertussis is a catarrh with a cough violent out of proportion to the inflammatory irri- tation, Aconite and Ipecacuanha precisely cover it, and will every now and then extinguish it. But when it becomes a pure spasm, it has passed the reach of these remedies, and Drosera, Belladonna, Corallia and such like take their place. The same holds good of Baptisia and Arsenicum in the first and second stages of gastric fever, and is familiar to you in the relation of Mercury and Iodide of Potas- sium to primary and secondary syphilis. Recognising this principle of stages, and carefully allotting our remedies to varieties, I think we may in acute disease make the single medicine the rule rather than the exception.* * Upon this subject you should read a paper by Dr. Neville Wood (‘ Annals,’ vol. i, p. 316), with the discussion at the British Homoeopathic Society which followed its reading. 36 ALTERNATION. 4. The above question borders closely upon that of alternation, on which I now desire to say a few words. What are you to do when no one medicine covers all your patient’s symptoms ? In chronic disease I think there can be no hesitation about the answer to the question. You should give the medicine which corresponds to the symptoms of greatest weight, and let it play its part before you bring any other to bear. The adoption of a different course would lead to confusion, certainly in the results of your practice, and probably in the organ- ism of your patient. Save in a few instances, where the exception is warranted alike by reason and experience, the rule is never to give more than one medicine at a time in chronic disease. But again acute disease gives a different aspect to the question. There is often no time to wait till the effect of one medicine is exhausted before you give the other; nor can you stay with your patient to watch the fitting hour for the change. So that upon the ground of practical expediency only we are sometimes driven to alternate, since we are unwilling to mix. Then again there are the cases brought forward by Dr. Bussell, in which two morbid processes, as variola and typhus, run their course in the system at the same time. This, which in Hahnemann’s day was thought impossible, necessitates a modification of the rigidity of his rule to give only one medicine at a time; and encour- ages us further to believe that two medicinal actions, as well as two diseases, can work side by side with- out interference. Nor are there wanting other in- ALTERNATION. 37 stances in which the use of more than one medicine at a time seems justifiable. The pathological pro- cess we call dysentery finds its pi’ecise analogue in Mercurius corrosivus ; and very often this medicine alone is all that we require. But sometimes the fever, sometimes the tormina, sometimes the haemor- rhage, sometimes the tenesmus—are so severe, that an alternating remedy suited to the predominant trouble seems to have a raison d’etre, and is cer- tainly useful. So when hooping-cough becomes complicated with bronchitis,—it would hardly be wise to omit your remedy for the neurosis because you have to give one for the phlogosis: and so you must alternate. All these cases are very different from the slipshod practice of alternating two medicines as a matter of course; or because you think them equally well indicated, and cannot choose between them. This has but to be mentioned to be condemned. Alternation should always be practised—not “under protest,’* but—as an exceptional proceeding. The exception is in part practical only, and may disappear with advancing knowledge. As we often supersede two opposite half-truths by some deeper whole truth which embraces them both, so in many instances in which we now alternate two medicines one may be discovered which shall cover all the symptoms. I think, indeed, that we often alternate unnecessarily as it is. But I am disposed to believe that to some extent alternation is founded on principle ;—that there are (the illustrations are Dr. Madden’s) double stars in the firmament of medicine, compounds which are themselves radicles in therapeutic chemistry. 38 AUXILIARIES. I do not refer to such medicines as Hepar sulphuris, which is a compound of Sulphur and Calcarea. The combination here is chemical, and it has been proved as a simple drug. The “ binary Homoeopathy” of which I speak is vital and not chemical : the reactions of the medicines are not one with another, but with the organs whose different tissues they influence. I will only hint at this now : it is an inquiry which needs working out. But just to indicate what I mean — I can hardly conceive a medicine more homoeopathic to the fever of measles than Aconite, and evil always results from its sus- pension ; and yet you must alternate other medicines with it if you want to relieve the coryza, the bron- chitis, or the diarrhoea from which your patient may be suffering. For further suggestions towards the basing of occa- sional alternation on fixed principles I refer you to the papers of my friend Dr. Drysdale in the 4 —i.e. where the catarrh invades only the trachea and largest bronchi—it is of little use beyond. In animals poisoned by Kali bichromicum it is noted that the bronchise were inflamed as far as their ramifications could be traced. My own ex- perience with it is that, in most cases of simple bronchitis, if, after Aconite has expended its action, any other medicine is required to modify the condi- 308 BRONCHITIS. tion of the inflamed tissue, Kali biehromicum will do it. It is also very effectual in the bronchitis of influenza. We have here a general condition which demands, not Aconite and cold water, but Arsenicum and champagne. When the influenzal catarrh runs down into the bronchial tubes, Arsenic will not fol- low it; and here Kali biehromicum comes in most usefully. There is one symptom often present in these cases, which is especially characteristic of the remedy now under notice. This is a thickly coated tongue, which, with loathing of food, indicates that the catarrh has involved the alimentary passages. Every now and then a case will occur whose symptoms remind you of the phenomena which, in susceptible persons, follow the inhalation of Ipecacu- anha. One such instance I have recorded in my paper. In these attacks—midway between bronchitis and asthma, half neurosis and half phlogosis—the power of Ipecacuanha is very great. 2. Capillary bronchitis, as constituting one of the pulmonary affections of childhood, will come under our notice later on. At present I shall consider it as it occurs in old persons,—the “ peripneumonia notha” and “suffocative catarrh” of the older writers. The grand remedy for this dangerous dis- order is Tartar Emetic. Perfectly homoeopathic to both the local and the general condition, I have almost invariably relied upon it single-handed, and have seen desperate cases recover under its use. Arsenicum is often recommended: but I cannot see its homoeopathicity, and have never used it. The danger in these subjects is from paralysis of the lungs. I have suggested (Pharmacodynamics, p. 273} BRONCHITIS. 309 the homceopathicity of Solania, the “ active princi- ple” of Dulcamara, to this condition: and from what I have seen of its action in chronic semi- paralytic coughs should try it with much hopefulness. 3. Toxsemic bronchitis is liable to be set up by the specific poisons of measles, of typhus and typhoid fever, and of gout, and by the excess of urea in the blood which obtains in chronic Bright's disease. Of the first I have already spoken, and shall speak again. The bronchitis of fever gene- rally calls for Tartar Emetic. In that which occurs in sufferers from chronic Bright’s disease, I would suggest Mercurius corrosivus, which is ho- moeopathic to the primary malady, and in a case of poisoning by which, recorded by Dr. A. Taylor, the bronchial mucous membrane was found inflamed throughout its course. The connection of bron- chitis with gout has lately been insisted upon by Dr. Headlam Greenhow. If the disease proved obstinate in a patient owning this diathesis, I should be disposed to give him the benefit of the as yet mysterious powers of Colchicum. 4. Chronic bronchitis presents itself under such various forms, that it is well-nigh impossible to lay down any general laws for its management. Each case requires to be studied as an individual, and to be treated on its own merits. But I will make an attempt to classify its leading varieties, and to sug- gest their most suitable treatment. I will base my classification on the pathological character of the expectoration,—viz., whether it is mucous, puru- lent, or fibrinous. a. In chronic bronchitis with mucous expectora- 310 BRONCHITIS. tion, the choice generally lies between two great medicines,—the determining symptoms being the consistence of the mucus. If it come up in lumps, be easy to detach and expel, or difficult only be- cause of the muscular debility present, Tartar Emetic is usually the remedy. But where the sputa are difficult and tenacious, and come up in long strings of opaque white mucus, the preference should be given to Kali bichromicum. This indica- tion for the latter medicine, which has been verified over and over again, w'e owe to Dr. Drysdale. b. Chronic bronchitis with puriform expectora- tion is a very serious matter. In cases of mode- rate severity I have seen Mercurius in the medium dilutions of great service. Perhaps Silicea, w'hich Teste commends highly in chronic bronchitis, may find its place here. China will at all events be useful in sustaining the constitution. c. If you meet with the rare form of chronic bronchitis, in which semi-membranous expectora- tion (bronchial polypi) occurs, Dr. Curie’s experi- ments would point to Bryonia as its most homoeo- pathic remedy, though Kali bichromicum is hardly less so. In all forms of bronchitis, but especially in the influenzal and the senile varieties, the cough is sometimes violent quite out of proportion to the local affection. We have here to call in the help of the neurotic drugs, the chief of which are Senega, Hyoscyamus, and Conium. Hyoscyamus is gene- rally a capital medicine for such a cough occurring in influenza,—the characteristic indication being aggravation on lying down. In old persons, where EMPHYSEMA. 311 the cough is harassing, I have much confidence in Senega. These neurotics may be given at the same time with the more strictly curative remedies, either in alternate doses, or (which I think better) the one by day and the other by night. Sometimes even, both in acute and in chronic bronchitis, we have to depend upon the neurotic in preference to the tissue-irritant medicines. I have already spoken of Ipecacuanha in acute bronchitis; and not uncommonly in chronic ie winter-cough ” you will find no medicine so efficacious as Nitric Acid. Sequelse or concomitants of bronchitis are Bronchi- ectasis, Emphysema, and Asthma. Bronchiectasis (dilatation of the bronchi) I take to be pathologically the same lesion as emphysema, only seated in the air-tubes instead of the air-cells. I have only seen one case of it; it ended fatally by abscess of the lung. Beyond the general roborant treatment obviously suitable to all degenerations, I have nothing to suggest as regards its management. Emphysema. When this lesion is partial and mechanical, as from the coughing of pertussis and bronchitis, medicine can have little to say to it. There seems no doubt, however, that emphysema, in its local and most important form, is a primary degeneration of the pulmonary vesicles, constitutional and here- ditary, often appearing to be a manifestation of 312 ASTHMA. gout. If we only knew further what was the nature of the degeneration,—whether fatty, fibroid, and so on,—we might find specific remedies for it, and so at least prevent the farther yielding of the cell walls. The hypothesis of fatty degeneration is supported by Rainey, Williams, and Chambers : but Dr. Waters’ more systematic investigations do not sustain it. It is a pity : for in that case Phospho- rus would have bid fair to help us greatly. But if we are driven back upon simple functional debility of the elastic fibres which conserve the diameter of the air-cells, then morbid anatomy will not help us to the remedy. Symptomatology is equally at fault; and experience is silent, at least so far as our lite- rature is concerned. I have myself treated one well-marked case of idiopathic emphysema for months with Phosphorus, Nitric Acid, and Nux vomica with little result. Perhaps the frequent alliance of the malady with gout may give us a useful hint, as it does with regard to Asthma : and Sulphur may prove as valuable here as there. Whatever medicines we use, the general man- agement of the patient must be of the character indicated by Drs. Waters and Chambers, including (if you like) the administration of iron as a food. Bronchitis, when occurring in emphysematous sub- jects, is of a low type, and attended with profuse secretion : Tartar emetic will be its medicine from the outset, and free stimulation seems indispen- sable. Asthma. I of course limit this term to true idiopathic ASTHMA. 313 paroxysmal dyspnoea, and do not include under its heading the varieties of difficult breathing which are sometimes miscalled “ Asthmatic.” Yet I can- not distinguish it as “ spasmodic asthma,” for I think it has yet to be proved that spasm is of the essence of the affection. I know few more inter- esting pieces of pathological reasoning than Dr. Russell's argument* that the dyspnoea of asthma is a morbid exaggeration of the normal besoin de rescuer, and that no real asphyxia is present or imminent. Dr. Russell follows up his discussion of the na- ture of asthma by a study of the remedies most suitable to meet it. If to his remarks you will add the paper of Dr. Blundell in vol. ii. of the “ Annals,” p. 1, with the discussion following, you will have got the substance of the experience of our school hitherto in its treatment. First, what can we do in the paroxysm? Have we any medicines which give speedy relief? or must we resort to the Stramonium-smoking or in- halation of the fumes of nitre-paper in vogue in the old school? The latter, at least, is harmless enough if it is needed. But very often our reme- dies act with great rapidity. In pure nervous asthma, uncomplicated with bronchial irritation, Cuprum and Lobelia are most effectual. Drs. Rus- sell and Drury each give a case illustrating the virtue of Cuprum; and I myself, in common with many other practitioners, have seen very satis- factory results from Lobelia, not given as an emetic or depressant, but from the 2nd to the 6th dilu- * See his ‘ Clinical Lectures/ Lect. ix, x; “On Asthma.” 314 ASTHMA. tion. When the asthma is bronchitic, I agree with Drs. Russell and Blundell in considering Aco- nite the best palliative. Its use by inhalation may be conjoined, as recommended by these physicians. It is to this variety that I consider Ipecacuanha homoeopathic, and not, as Dr. Russell seems to think, to pure nervous cases. It is especially indi- cated where there is much cough. When by these or other means you have got your patient through his paroxysm, you will have to consider the best means for obviating the ten- dency to its recurrence. The medicines I shall mention under this head are Nux vomica, Arseni- cum and Sulphur. Nux vomica is about the best curative medicine we have for simple “ spasmodic ” asthma, where there is no bronchial lesion, but a standing reflex excitability of the pneumogastric to impressions from without or through the stomach. One of the early cases which made Hahnemann famous was of this kind: and the Nux was given in material doses. Dr. Kidd, also, states that he considers it our best anti-asthmatic. While giving you con- fidence in the medicine, his testimony may also suggest the doses in which you should use it.* * I can confirm the following remark of Dr. Russell about this drug. “ After the paroxysm subsides, it leaves a condition of the digestive organs for which Nux Vomica is the great remedy. The tongue is coated with a thick, yellow fur; there is often slight nausea, flatulence, and constipation. Besides, the breathing is seldom quite right; generally there remains a sort of physical memory of the struggle. The patient feels that no liberties must be taken, either of diet or exercise. Out of this secondary state of bondage nothing will liberate so effectually as Nux Vomica.” ASTHMA. 315 Arsenicum is the best medicine where bronchitic asthma tends to become, or has become, chronic. Of this Dr. Russell furnishes several illustrations: and you cannot do better than read them in his capital lectures. The same medicine may still farther benefit asthmatic sufferers by relieving the symptoms of the heart disease to which they are nearly always, sooner or later, subject. In a great number of cases of asthma you will discover on inquiry gouty inheritance or proclivity, or, what is almost the same thing, some form of cutaneous disease alternating with the dyspnoea. In these cases you will get most satisfactory results from Sulphur. You may send your patients to a sulphureous spring, as Dr. Russell recommends; but I think they will do nearly as well at home under the usual potencies of the drug, of which here I prefer the lowest. LETTER XXXIII. DISEASES OP THE RESPIRATORY ORGANS (iContinued). I propose, in the present letter, to discuss the treatment of the hypersemic affections of the pul- monary parenchyma, i. e. the air-vesicles them- selves. I begin with pneumonia. Pneumonia has been one of the great battle-fields of statistics. After it had been shown what per-centage of cases bloodletting, and tartar emetic, and calomel could kill, Expectancy stepped in to demonstrate that a larger proportion recovered when left alone, and Homoeopathy declared that its treatment gave a lower death-rate still, and a shorter average dura- tion of disease.* But alas ! we have been outdone by Prof. Hughes Bennett, whose results would lead us to believe that under a system of judicious ma- nagement, with small doses of tartar emetic at the beginning, and nutrients and stimulants later, no uncomplicated case of pneumonia need be lost. I have myself very little faith in statistics, when applied to so difficult and delicate a subject as the- rapeutics. But I can sketch to you a treatment of pneumonia which partakes neither of the lowering * See Dr. Henderson’s paper in ‘ Brit. Journ. of Horn.,’ vol. x, p. 629. PNEUMONIA. 317 and spoliative measures of our forefathers, nor of the other extreme of stimulation into which the present age has rushed : but which, while rational in its method, gives obvious relief to the symptoms, shortens the duration of the disease, and will rarely permit your patient to slip through your fingers. I will speak first of the typical form of the dis- ease, as it occurs from chill in tolerably healthy adults. If you see your patient sufficiently early, while the fever—as marked by pulse and temperature—• is still high, you are sure to be doing right if you give him a few doses of Aconite. The observations of Dr. Parkes make it appear that in pneumonia the fever is out of all proportion to the local in- flammation, and runs an independent course of its own,—defervescence (which is very rapid) occurring at or even previous to the height of the consolida- tion. If we can anticipate this crisis by our Aconite, as probably we can, we shall be rendering an unquestionable benefit to our patient, whose distress depends far more on his general than on his local symptoms. If, moreover, Drs. Stokes and Waters be right, that there is a stage of pneumonia prior to that of engorgement, characterized by dry- ness and intense arterial injection of the pulmo- nary membrane, and revealing its presence to the ear by a harsh, loud, puerile, respiratory murmur in the very spot where dulness and crepitation are afterwards discovered,—if, I say, these observers are right, Aconite may fairly be expected at this stage to extinguish the whole morbid state unaided. Aconite is not a specific irritant of the lungs; 318 PNEUMONIA. and if within twenty-four hours of its administra- tion the symptoms have not materially abated, or if general fever has already ceased to be a prominent feature, it is useless. Our grand remedy then is Phosphorus. We owe the establishment of its re- putation to Dr. Fleischmann of Vienna: hut it has since gained universal confidence. Its only rival is Bryonia, for which Tessier has done in Paris what Fleischmann has done with Phosphorus in Vienna. It is not easy to decide between the two. Bryonia would undoubtedly be more suitable to pleuro-pneumonia, and Phosphorus to broncho- pneumonia. But I apprehend that both these diseases are rare; and tha$ the bronchitis and pleurisy associated with pneumonia are generally secondary and partial extensions of the primary inflammation of the pulmonary tissue itself. The only other medicine I have to mention in connexion with acute pneumonia is Tartar Emetic. I have already argued out the unconscious homceo- pathicitv of the common use of this drug in pneu- monia. Its reputation, as usual, has been injured by the quantities in which it has been given. I am glad to find Dr. Waters writing, “ It is rarely, if ever, necessary to give it in large doses. From one sixteenth to one fourth of a grain I have usu- ally found quite enough.” I think it rarely appli- cable in the primary form of the disease. Its pathogenesy shows it to be most suitable when the inflammation has run down from the air-tubes into the cells (catarrhal pneumonia), and when exuda- tion is free and early. We have both these con- ditions present in the pneumonia of epidemic PNEUMONIA. 319 influenza, and here Tartar Emetic is specific. Of its action in the neighbouring capillary bronchitis I have already spoken. You will find some valuable remarks on the place of these four medicines, Aconite, Phosphorus, Bryonia, and Tartar Emetic, in the treatment of pneumonia, in an editorial article on the disease in vol. ix. of the British Journal. Also by Dr. Clotar Muller on Phosphorus and Tartar Emetic in Laurie’s ‘ Homoeopathic Practice of Physic/ p. 282. The only other medicine I think likely to be added to the list is Chelidonium. All I can say of it at present is that it is likely to prove useful when the right lung is inflamed and the liver involved. But I have hitherto been speaking only of pneu- monia in its typical form, and in its ordinary course. I have not included in the latter the occurrence of suppuration. This rare event has not had any definite treatment assigned to it. Dr. P. P. Wells recommends Lachesis and Cannabis sativa (American Horn. Bev., vol. iv, p. 100), Dr. Drvsdale Sanguinaria (Monthly Horn. Rev., vol. x, p. 115). Of circumscribed pulmonary abscess I will speak presently. If gangrene should occur, Lachesis and Arsenicum would be indicated. Again, if pneumonia supervened in the course of continued fever, you of course would not think of Aconite: but Phosphorus or Bryonia would still apply, or Tartar Emetic if there had been previous bronchitis. The latter medicine would also seem suitable to the pneumonia which sometimes com- plicates delirium tremens. 320 HEMOPTYSIS. I have only to add that when the exudation is slow in taking its departure, or the disease threatens to become chronic, Sulphur should be given. For simple chronic pneumonia itself, should you meet with that very rare affection, Lycopodium is a valuable remedy. Abscess Of the Lung (non-tubercular) I believe to be more common than is usually sup- posed. I myself have seen five well-marked cases of it. Under suitable climatic conditions, there is nothing to prevent its being recovered from :— Iodine and China being the medicines most helpful towards such an issue. Congestion of the Lungs stands on the other side of pneumonia, and is also, though rarely mentioned in text-books, far from uncommon. If it originates in a chill, Aconite may be necessary: but Phosphorus is the really important medicine. Mechanical congestion of the lungs is of course common enough in cardiac disease: but this you must treat from the side of the heart. Haemoptysis. A word is sufficient to say that in pulmonary haemorrhage from mechanical violence, Arnica is sufficient: and that when it constitutes a vicarious menstruation, Bryonia is said to be efficacious in (EDEMA PULMONUM. 321 restoring the menstrual haemorrhage to its proper place. The haemoptysis of cardiac or aortic disease is generally the result of mechanical embarrassment of the circulation : and would be helped by Aconite, or by Digitalis if the heart be dilated and feeble. And now we have left the most important and frequent variety of this haemorrhage; that occurring in connexion with pulmonary tubercle. In sanguine temperaments, and when the pulse is full and bounding, Aconite is indispensable here, and may be all that is required. I confess I have never had occasion to use it. The two medicines on which I have learnt to rely are Millefolium and Hamamelis, in the 1st dilution of each. The former is most suitable when the haemorrhage is predominantly arterial, the latter where it is venous and passive. Other medicines of importance are Ipecacuanha and Ferrum Aceticum, for the latter of which I refer you to the ‘ Annals/ vol. v, p. 409. Pulmonary Apoplexy is, therapeutically, the same thing as haemoptysis, and can be helped by no other treatment. So much for the hyperaemiae of the lungs : but before passing to phthisis let me say a word upon (Edema Pulmonum. Drs. Wurmb and Caspar, in their reports of the Leopoldstadt Hospital, mention more than once 322 (EDEMA PULMONUM. having cured this condition with Tartar Emetic. I myself have seen oedema of the lungs, occurring in the course of general dropsy, subside entirely under the use of the same medicine. I gave it, as they did, in the 12th dilution. LETTER XXXIY. DISEASES OF THE RESPIRATORY ORGANS (iContinued). I shall begin my present letter with the thera- peutics of Phthisis Pulmonalis. I desire to yield a hearty and ungrudging tes- timony to the advance which Old Medicine lias made in the treatment of this disease. There is no doubt that the mortality is less, and the duration of life greater, in phthisis than it was thirty years ago : and it has been a genuine triumph of scientific investigation. The unanimous consent of all the teachers of the present day as to the principles of treatment to be observed in phthisis is worthy of admiration : and commends the method to us with unwonted force. When we examine the method in question, however, we find it to be purely regiminal and dietetic,—the iron and cod-liver oil which are the only “ medicines ” given falling under the latter heading. And herein is illustrated that which Dr. Madden has insisted upon,—that the recent ad- vances made in the old school are on the com- mon ground of hygiene, and have no relation to the administration of drugs. We can thankfully 324 PHTHISIS FULMONALIS. recognise and adopt them : while in our own department of specific medication we still, unhappily, stand alone. Some day we hope that prejudice will no longer “ to the marriage of true minds Admit impediments.” Let it be fully understood, then, that the basis of the treatment of phthisis must be with us as with others hygienic. Let us nourish our patient well and wisely; let him always breathe fresh air, and take plenty of exercise ; choose his climate for him if possible; and give him cod-liver oil and— save in the rare “ phthisis florid a ”—chalybeate food. But Homoeopathy will enable you to do more than this. It will enable you to keep down pulmonary inflammation without lowering the sys- tem. It will give you “ cough medicines” Avhich will not spoil the stomach, “ alteratives ” free from the poisonousness of mercurials, and remedies for diarrhoea which do not constipate. It has even means of no slight energy for modifying the tuber- cular diathesis itself. Let me tell you all I know about the medicines which are useful in phthisis. 1. The most recent researches “ leave very little room for doubt that the bad habit of body in scrofulous affections associated with the growth of tubercle-matter must be established in the first instance through the digestive processes, as first described by the late Dr. Tweedy Todd under the name of strumous dyspepsia, and which has been since so fully described by Sir James Clark, Bennett, Hutchinson, and others” (Aitken). The PHTHISIS PULMONALIS. 325 characteristic features of this strumous dyspepsia are dislike to and difficulty in the assimilation of fats, “ biliousness/’ heart-burn, flatulence, and, above all, acid eructations after taking food. Such dyspeptic symptoms, when ordinarily occurring, call for Calcarea carbonica and Pulsatilla. The former medicine, specially indicated by the acid eructations, would be quite in place here: but I think that only temporary and superficial benefit could be expected from Pulsatilla. The mischief lies, I suspect, not so much in the stomach, as in the organs devoted to the assimilation of fatty matters,—the pancreas and the mesenteric glands. Iodine is the medicine which has the greatest control over these: and on Iodine, with an occa- sional dose of Calcarea, I would advise you to rely whenever you meet with phthisis in this “ pre- tubercular stage.” Test your patient's progress by his temperature and his weight rather than by the sounds of his chest: and direct your attention to his stomach rather than to his lungs. 2. When phthisis has thoroughly localized itself in the lungs, although Calcarea and Iodine are still very good, and in the absence of indications for special medicines may be persevered with, yet urgent needs generally call for other remedies. Above all, we have to keep down pulmonary irri- tation and hypersemia : and for this purpose Phos- phorus is invaluable. Not only in intercurrent attacks of inflammation, but continuously, this medicine may be given with advantage. When the pneumonic symptoms are more chronic and passive in character, especially in young men, Lycopodium 326 PHTHISIS PULMONALIS. is even preferable to Phosphorus. The cough, which is the most troublesome symptom in this stage, may be sufficiently moderated by these means: but often requires a medicine to itself, which you may find in Ipecacuanha, Hyoscyamus, Drosera, or Kali carbonicum, according to the symp- toms present.* 3. Again, our patient comes to us when softening has set in, and when puriform expectoration brings hectic in its train, whose colliquative sweats are matched by diarrhoea, and its exhausting influence enhanced by vomiting of the ingesta. It is by checking this hectic, this diarrhoea, this vomiting that medicine can give most help in the present stage. If Iodine and Phosphorus have now lost their power to modify the symptoms (Calcarea and Lycopodium have long been left behind), other remedies will come into play. China and Phos- phoric Acid will oppose the hectic, if you will not be afraid to give them (the former especially) in pretty full doses. Arsenicum (3rd dec. trituration) has often in my hands arrested the diarrhoea. Kreasote (2nd) is specific against the vomiting : and Dr. Hilbers credits it with a supporting and resto- rative influence over the whole system. These are the medicines from which I think you will gain most help in your endeavours to arrest the progress of phthisis in its several stages. Too often, alas ! your best-directed efforts will fail, and * I.e. Ipecacuanha and Drosera when the cough is spasmodic, with retching : Hyoscyamus when it is much increased at night and on lying down; Lachesis and Kali Carbonicum when it seems kept up hy irritation of the fauces and pharynx. PHTHISIS PULMONALIS. 327 increasing exhaustion and emaciation with uncon- trollable diarrhoea and commencing aphthae herald the fatal issue. Still perseverance in what might be curative will be found palliative: and will best promote the euthanasia. I can say nothing as to our per-centage of cures until we have a Con- sumption Hospital: but I can answer for the power of our system to smooth the passage to the grave. And now a few words upon varieties and compli- cations of phthisis. Acute pulmonary tuberculosis I have seen arrested by Arsenic and Phosphorus; Mr. Pope, in his excellent paper on the therapeutics of Consumption in vol. xx of the British Journal, speaks of a case in which Arsenic and Calcarea effected a cure. The same writer, following Dr. Clotar Muller, calls attention to the well-known fact that Iron, injudiciously administered, often brings on ha3mo- ptysis and phthisis: and suggests the homoeopathicity of Ferrum to the form of disease known as ft phthisis florida.” If laryngeal symptoms should supervene in the course of phthisis, you may give Spongia with good hope of success : but primary laryngeal phthisis is another matter. Iodine and Drosera would promise most in its treatment: but the few cases I have seen have invariably gone on from bad to worse. Of the intercurrent pleurisy of phthisis I shall speak when I come to the former disease. I cannot but feel that we are on the eve of a revolution in our pathological notions of pulmonary phthisis. On the one side, we have experimental researches into the inoculability of tubercle, which 328 PULMONARV SYPHILIS. are leading to unexpected conclusions as to its nature and history. On the other, the cases called “ phthisical ” are being analysed and distinguished ; and many other pulmonary deposits besides genuine miliary tubercle are shown to be capable of causing the phenomena which go under its name. Thus we hear of “ scrofulous or epithelial phthisis,” of “ pneumonic phthisis,” of “fibrous,” “amyloid,” “syphilitic,” “haemorrhagic,” and “embolic” phthisis (see Dr. Andrew Clark’s table in Aitken, vol. ii, p. 760). In time our therapeutics of the disease will have to receive a parallel development: and we shall probably learn what were the varieties of the disease which the older Homoeopaths curSd with Kali carbonicum, Sulphur, and Stannum. For the present, this must suffice. A few words before I end this letter upon syphilis and cancer of the lungs. Pulmonary Syphilis is described as occurring in two forms. It may be a chronic bronchial irritation, with the general symptoms of phthisis, complementary to the se- condary cutaneous syphilides. Or it may consist in the deposit of gummatous nodules, which some- times soften like tubercle (syphilitic phthisis). In the former variety the Iodides of Mercury would probably prove specific: in the latter I cannot suggest any improvement upon the ordinary use of Iodide of Potassium. PULMONARY CANCER. 329 Pulmonary Cancer must be named here, for the sake of completeness : but I have no information to give or suggestions to make as to its treatment. It is happily very rare. LETTER XXXV. DISEASES OF THE RESPIRATORY ORGANS (Continued). In the present letter I shall speak of the affec- tions of the pleura, and of those of the thoracic walls, concluding with a few remarks on the treat- ment of injuries of the chest. Pleurisy is a disease the Homoeopathic treatment of which is as well established as is that of pneumonia. If you will read the monographs upon it by Drs. Wurmb and Trinks in vol. i and by Dr. Beilby in vol. x of the ‘ Brit. Journ. of Homoeopathy/ and further look out in the index for the separate cases of the disease -which have been published from time to time, you will see a remarkable uniformity in the medicines given by different practitioners in the recognised varieties and stages of the disease. These are as follows. In simple acute pleurisy, arising from exposure to cold in a healthy person, and beginning with a dis- tinct rigor, Aconite is the one sufficient medicine. The pleura is one of the few parts to which it is a specific irritant: hence it covers the whole disease. The effusion in these cases is rather plastic than serous: and should its re-absorption be delayed, PLEURISY. 331 Dr. Wurmb highly commends Sulphur as a medicine capable of hastening it. Still farther off from the primary disorder, a lingering deposit of lymph has disappeared under the action of Hepar Sulphuris (see a case in fBrit. Journ. of Horn.,’ vol. xviii, p. 162). But I must admit that this typical pleurisy is rarely seen. Without speaking now of the occur- rence of the disease as a secondary lesion, it com- monly sets in after a more insidious manner, with no distinct rigor, and with early serous effusion. Hence the great anti-pleuritic is the remedy for this variety of the disease, Bryonia. You will remember my citations from Trinks as to the place of this medicine in all serous inflammations (Pharmaco- dynamics, p. 168). Consider in addition the Reports of the Leopoldstadt Hospital, in which Bryonia stands from year to year at the head of the remedies for pleurisy: and you will see that an almost in- variable use of it in this disease is well warranted. When the (serous) effusion is very rapid and copious, Bryonia must be replaced by or at least alternated with Arsenicum. Dr. Wurmb speaks of this medicine in pleurisy as follows. “Arsenic is especially indicated in serous pleurisy, and our con- fidence in it is so great, that we wholly despair of the possibility of curing a case of serous pleurisy in which Arsenic has produced no beneficial change at all, as in the art-defying haemorrhagic diathesis. The first good effects of Arsenic are manifested by the alleviation of the painfully asthmatic respiration ; after this the dropsical swellings abate, the febrile attacks become less frequent, and at length the 332 HYDROTHORAX. absorption of the effusion takes place . . . Arsenic is also one of those medicines which do good speedily, if they are to do good at all.” Secondary pleurisy, when calling for special attention, is to be treated upon the principles already mentioned. If it supervene upon rheumatism, you will continue your Aconite and Bryonia. If it occur in connexion with pulmonary tubercle, Bryonia may suffice; but it is here that Kali carbonicum has attained so much repute. The pleurisy attendant on Bright's disease would pro- bably be helped by Arsenicum in preference to any other medicine, This brings us to Hydrothorax, ■which may be either serous pleurisy in its chronic stage, or a secondary dropsy. In the latter form Apis and Apocynum are said to have proved cura- tive ; but I should have much greater reliance upon Arsenicum. Indeed I think Apis much more suit- able when hydrothorax has remained behind after pleurisy. Iodine, in some of its forms, appears in as high repute as ever for causing the absorption of pleural fluid : and I have already mentioned obser- vations which go to show that Iodide of Potassium can cause pleurisy, and that effusion into the pleura may be found as the result of poisoning with Iodine (‘ Pharmaco-Dynamics/ p. 321). PLEURODYNIA. 333 Empyema undoubtedly requires paracentesis for the evacua- tion of the fluid. But when you have effected this, you may find in Silicea a potent means of prevent- ing fresh suppuration. You might inject it into the cavity of the pleura, besides giving it internally. Do not forget, also, the power of China over the hectic which drain of pus excites. Pneumo-thorax must be mentioned here : but it is obviously out of the range of medicinal influences. The thoracic walls are the seat of Pleurodynia. I include under this heading every form of pain occurring in the chest walls. Pleurodynia, in this extended application, may be either a rheumatism, a myalgia, or a neuralgia. 1. In rheumatic pleurodynia you will give Aconite, in repeated doses of a low dilution, if the attack be recent, especially if fever be present. But unless speedy relief is obtained, you will do well to substi- tute remedies having more local affinity with the thoracic walls. Bryonia, Actcea racemosa, Ranun- culus bulbosus, and Colchicum are all more or less homoeopathic and curative. I should choose the first where the rheumatic diathesis was marked: the second for women: the third where the pain 334 INJURIES OF THE CHEST. was very intense, so that the patient dare not move (see Dr. Dudgeon’s case in vol. xxiv of the ‘ Brit. Journal/ p. ICO) : the fourth where a gouty as well as a rheumatic tendency was present. 2. Myalgic pleurodynia has also found its remedy in Ranunculus, as in some cases by Dr. Strong in the ‘Monthly Horn. Review* for Dec. 1866. But its chief medicine is Arnica. When it resembles pleurisy so much as to render diagnosis very diffi- cult (“ spurious pleurisy **), a few doses of this drug will often clear up the question by extinguishing the symptoms. 3. Neuralgic pleurodynia (intercostal neuralgia, infra-mammarypain) appears under twoleadingforms. First, in young women otherwise fairly healthy, where it is hysterical, or otherwise symptomatic of deranged uterine function. Here Actcea Racemosa is specific. Secondly, as an idiopathic neuralgia in anaemic or debilitated subjects. In these Arsenicum or Ranunculus again will relieve the pain; but its return must of course be guarded against by mea- sures suited to build up the system at large. Injuries of the Chest —I refer especially to penetrating wounds—derive tlieir chief importance from the strong tendency to inflammatory excitement which occurs. You must carefully be on the watch for this: but should it appear, you may trust to Aconite to do at least as much as the usual bloodletting to allay it. COUGH. 335 APPENDIX TO DISEASES OF THE RESPIRATORY ORGANS. Cough is such a frequent accompaniment of the affections of the air-passages and chest that I have thought it well to append here a special list of cough medicines, noting briefly under each the symptoms which call for its use. Acidurn nitricum. Spasmodic cough. Ambra. Hysterical cough. Ammonium carbonicum. Incessant cough excited by a sensation as of down in the larynx. Antimonium tartaricum. Cough with profuse and easy mucous expectoration. Arsenicum. Cough of asthmatic subjects and of cardiac disease. Belladonna. Dry spasmodic cough, with deter- mination of blood to the head; pertussis in second stage. Bromine. Laryngeal cough, with hoarseness. Bryonia. Dry, irritative, shaking cough, worse in day-time; tickling, or heat and soreness behind sternum; pains in walls of chest and abdominal muscles. Causticum. Laryngeal cough, dry; urine spirts out during paroxysm. Coccus cacti. Violent cough causing vomiting and expectoration of much thick mucus. Conium. Nocturnal cough, dry, hacking, and almost continual. Corallia rubra. Nervous, spasmodic, and hys- teric cough ; second stage of pertussis. 336 COUGH. Crotalus. Cough of phthisis. Drosera. Spasmodic cough, worse at night, with retching : second stage of pertussis. Hepar sulphuris. Laryngeal cough, with expec- toration : hoarseness. Hyoscyamus. Nervous cough, continual hack- ing; worse on lying down. Often best in alterna- tion with Ipecacuanha. Iodium. Laryngeal cough, dry. Ipecacuanha. Spasmodic cough with mucous expectoration; retching and vomiting. Pertussis in first stage. See Hyoscyamus. Kali bichromicum. Laryngeal cough, with hoarse- ness : cough with tough stringy expectoration. Kali carbonicum. Chronic coughs of obscure chest disease, a bow to be drawn at a venture occasionally.* Lachesis. “ Throat-cough ; ” cough of cardiac disease. Lycopodium. As Kali carbonicum. Mercurius. Chronic bronchial coughs, -with puru- lent expectoration. Naja. Cough of cardiac disease and of phthisis. Nux vomica. Spasmodic cough, hurting head; “ stomach cough,” worse after food. Phosphorus. Cough of phthisis. Pulsatilla. Loose mucous cough in children : loose night-cough of pulmonary disease. Rumex crispus. Laryngo-tracheal cough, dry, irritating, incessant, aggravated by pressure, talk- * Also from irritation of relaxed uvula (see ‘ Annals,’ vol. iv, p. 543). COUGH. 337 ing, and inspiration of cool air : sense of excoriation behind sternum. Scilla. Tracheal coughs, with much expectora- tion. Senega. Dry, irritating cough, with pains about chest. Comp. Bryonia. Sepia. As Kali earbonicum. Expectoration greyish-white and saltish. Spongia. Laryngeal cough, dry. Stannum. As Kali earbonicum. Expectoration profuse, of greenish colour and sweetish taste. Sulphur. Cough of asthma, especially in gouty subjects. Verbascum. Hoarse dry night-coughs. LETTER XXXVI. DISEASES OF THE CIRCULATORY SYSTEM. Instead of passing from the Respiratory organs to the next great tract of mucous membrane,—the genito-urinary, I shall first review the disorders of the Circulatory system, with which the former are both anatomically and physiologically so closely con- nected. Under this heading I shall consider the diseases of the Heart, of the Arteries and Veins, of the Lymphatics and Lacteals, and of those ductless glands—notably the Spleen and the Thyroid— which functionally belong to the blood and its circulation. I take first the diseases of the heart. In their dis- cussion I shall follow closely in the footsteps of the late Dr. Russell, who, in his papers on cardiac dis- orders in the ‘British Journal of Homoeopathy’ (vol. xii), and in his ‘Clinical Lectures/ has done so much for this subject. With him I shall begin with Palpitation. Dr. Russell divides the cases of this disorder into those in which the primary evil is, 1st, in the heart itself, 2nd, in the blood, 3rd, in the stomach. 1. The heart beconms liable to palpitation from any cause which weakens its nervous energy. Such HYPERTROPHY. 339 are great mental exertion, anxiety or emotional tension of any kind, masturbation or excess in venery, abuse of tea and tobacco, and so on. To relieve an acute attack of this kind, there is nothing equal to Moschus. The chronic tendency may he obviated, if the exciting cause can be removed, and suitable regimen carried out, by such medicines as Lachesis and Naja, Glonoine, Digitalis, and Phos- phoric Acid. The last named is of course specially suitable where sexual excess has been the exciting cause. 2. The presence of the gouty poison in the blood, and ansemia, are frequent causes of palpita- tion. Treatment directed against the diathesis in the one case, and Iron in the other, are the curative remedies. Nux moschata would probably give temporary relief to palpitation of gouty origin. 3. Dyspeptic palpitation is often nothing but gout. When it owns no relation with that diathesis, you may with advantage remember what Dr. Elliotson says of Hydrocyanic Acid, that it is good for “ those disorders of the stomach which, in some of their symptoms, resemble affections of the heart.” Passing now from the functional to the organic diseases of the heart, I will take first those of its muscular substance, beginning with Hypertrophy. In the acute attacks of palpitation incident to this disease, Aconite takes the place filled by Moschus in nervous palpitation. The continued 340 DILATATION OF THE HEART. use of the same medicine is also very serviceable in relieving the permanent distress of these sufferers. A still higher value in this direction is assigned by Dr. Russell to Naja and by Dr. Rubini to Cactus Grandiflorus. A good case is given by the former illustrative of the value of his favourite medicine (‘ Brit. Journ/ vol. xii, p. 543). But whether with these or any other medicines you can actually reduce an hypertrophied heart is quite another question. The only form of the disease in which such a result may fairly be expected is, I think, that which results from violent exercise, as rowing. Here the curative medicine, as you may suppose, is Arnica (see Dr. Madden’s paper on f Myalgia ’ in the c Brit. Journ. of Horn.5 vol. xxv, p. 80, and Dr. Bayes’ observations on Arnica in the f Monthly Horn. Review ’ for Dec. 1866). The above remarks apply to hypertrophy, whether accompanied with dilatation or not. But we have now to consider Dilatation of the Heart itself. I have nothing to say against the usual prescription of Iron in this disease, but everything in its favour. I would only recommend you in its treatment always to add to your dietetics homoeo- pathy, in the shape of Digitalis. I am not going to re-open here the questions as to the cardiac action of this drug, which I have already discussed at length when writing to you upon it. I content myself with recommending to you its continued use. At the first appearance of dropsy in these cases it ANGINA PECTORIS. 341 may often be banished by Apis: but sooner or later Arsenicum will be required : and with the aids already mentioned will long keep it at bay. Fatty Degeneration of the heart presents itself under two forms. In the first, the fat is in the first instance deposited upon the heart, and the degeneration of tissue is secondary : in the second it is primary. The treat- ment varies accordingly. Patients of the former kind have to be urged to a diet and mode of life calculated to avoid obesity ; and perhaps Calcarea would be a useful medicine for them. For the medicines suited to the latter variety I refer you to an able paper by Dr. Drury in the f Brit. Journ. of Horn/ vol. xix. Arsenicum and Phosphoric Acid are the medicines he most favours : but I think that both must now yield the first place to Phosphorus, the power of which to produce fatty degeneration in the heart as well as the liver is undoubted. The chalybeate food on which most reliance is placed in the old school will harmonize as well with Phosphorus here as with Digitalis in dilatation. Angina Pectoris is generally considered to be a symptom of fatty heart and atheromatous coronary arteries. Dr. Anstie maintains that it is a neuralgia. But how. ever this may be (and the two views are not ir_ reconcileable) you will find Arsenicum a capita^ 342 PERICARDITIS. medicine for it. I do not mean in the paroxysms themselves, where at present no specific medicine* has availed to take the place of chloric ether: but given continuously to check their recurrence. Naja, also, has here again done good service, this time in Dr. Bradshaw’s hands (see ‘ Annals,’ vol. i, p. 296). When angina is plainly a spasm,—especially when there is a sensation as if the heart were grasped by a hand of iron,—Cactus is a better medicine than either. Pericarditis. The idiopathic form of this disease is so rarely witnessed : and so little is known either to Patho- logy or Therapeutics of its pysemic, haemorrhagic, or tubercular varieties, that I shall speak of its treatment only as occurring in connexion with acute rheumatism and in the course of Bright’s disease of the kidney. If in the progress of a case of acute rheumatism a double-friction sound begins to be heard, and the other sj'mptoms of pericarditis are setting in, you can nearly if not quite always arrest them in twenty- four hours by giving your Aconite alone in sufficient strength and frequency (a drop of the 1st dec. dilu- tion every hour or so), and covering in the heart with a hot linseed-meal poultice. Experto crede. But you are not always fortunate enough thus to catch the disease at its first breaking out, and must be prepared for its treatment in its several stages. You will begin by reading the cases narrated by * Spigelia, however, should be tried. ENDOCARDITIS. 343 Dr. Drysdale in the fBrit. Journ. of Horn/ vol. xii, p. 557, by Dr. Laurie in vol. v of the same Journal, p. 310, by Dr. Kidd in vol. xiii, p. 198, and by Dr. Russell in his ‘ Clinical Lectures,’ Lect. II. You will find that after Aconite, Bryonia, Colchicum, Spigelia, and Arsenicum are in highest favour. Bryonia has never been trusted to alone, but always in alternation with Aconite or Spigelia. I think the distrust only natural, and always suspend its administration in rheumatic fever in favour of other medicines when cardiac mischief sets in. Colchicum has no a priori evidence in its favour; but its action in Dr. Kidd’s and one of Dr. Laurie’s cases was not a little remarkable. Spigelia has the highest reputation, and has in its favour the testi- mony of Dr. Fleischmann, who uses no other medi- cine. Arsenicum is preferable to it only when serous effusion into the pericardial sac is consider- able. It is noted here by more than one observer that it frequently relieves the anxiety and oppression some time before the physical signs announce the resorption of the fluid. Armed with these medicines, you may with much confidence encounter the rheumatic form of peri- carditis. In that which occurs in Bright’s disease Colchicum and Arsenicum are the only members of the group likely to be called into requisition. And now of Endocarditis, which for all practical purposes may be considered exclusively in its connexion with rheumatism. You 344 CHRONIC VALVULAR DISEASE. will find a capital case by Huber in vol. xii of the * British Journal/ p. 562, where Aconite 1 was the only medicine : and another by Dr. Bayes in the £ Monthly Horn. Review 3 for June 1867, in which Spigelia proved effectual. Dr. Russell’s case, more- over, in the second of his c Clinical Lectures ’ was one of endo- rather than of pericarditis, though there was a little of the latter. Aconite was of most service, though several intercurrent medicines were required. Aconite and Spigelia are thus, in inflammation of the lining as well as the covering membrane of the heart, the principal remedies. This is only to be expected, when we consider the close similarity of the two textures, and the identity of the usual exciting cause. I must add Arsenicum, which has genuine endocarditis among its poisonous effects. The sequelae of endocarditis are the various forms of Chronic Valvular Disease. The power of Homoeopathic medicines to give relief to the sufferings of patients thus afflicted is very considerable. From Dr. Russell’s experience it seems that Naja should always be given during the convalescence from an acute endocardial attack, and has great power of ensuring complete recovery. Nor is it less useful as a palliative medicine subse- quently, when this happy result has not been obtained. Two other very useful medicines here are Cactus and Arsenicum. The former is most useful where there is hypertrophy with the valvular CHRONIC VALVULAR DISEASE. 345 disease, as in Dr. O’Brien’s case which I have cited when writing upon this medicine. Arsenicum is better when the right heart has become dilated, and dropsy is threatening. The acute paroxysmal attacks incident to valvular disease are best relieved by Camphor. This is all I have to say upon the treatment of cardiac disease. But you will forgive the brevity, when you see that it arises, not from scanty know- ledge of its remedies, but from their fewness in number, and their accurate adaptation to its varie- ties. I only wish I could dismiss with so few words the whole nosological series. LETTER XXXVII. DISEASES OE THE CIRCULATORY SYSTEM [continued). I am now going to approach a class of diseases most of which are sufficiently obscure patholo- gically, but which are still less known to thera- peutics. These are the diseases of the blood- vessels : of the lymphatic and lacteal system: and of the vascular glands. As diseases of the arteries I will consider arteri- tis, aneurism, and atheroma. Arteritis, if you ever diagnose it, would probably be met by the treatment suitable to endocarditis, viz. Aconite in low dilution and repeated doses. If it occurred in a superficial artery, as the carotid or the femoral, the local application of the same medicine in the form of a strip of rag soaked in a strong solution would be advisable. Aneurism, •when not amenable to surgical procedures, you will probably treat by the rest in the horizontal posture and the limited diet now usually adopted. In aid of such measures Aconite will again come in most PHLEBITIS. 347 usefully. It will give the relief from pain for which resort is so often had to bloodletting: and it will at least quiet the circulation to its norm. Lycopodium has some credit in the treatment of aneurism : and nothing would be lost by adminis- tering it during the intervals when Aconite is not required. Should a tendency to the recurrence of aneurism manifest itself, you must treat the un- healthy state of the arteries, as for Atheroma. If this change be, as is usually supposed, a fatty degeneration, we ought to have a useful medicine for it in Phosphorus. But I have already quoted Prof. Hughes Bennett's statement, that the fatty change here is not in the arterial tissue, but in the exudation of an arteritis. This would alter the case : and so, though we had better try what Phos- phorus will do, we must not be disappointed should it fail us. The diseases of the veins which we shall have to consider are phlebitis and varicosis. Phlebitis, in its most familiar form of phlegmasia alba dolens, will come under notice among the Diseases of Women. When occurring under other circum- stances, you will find two excellent medicines for it in Pulsatilla and Hamamelis. I hardly know to which to give the palm. The former would cer- tainly be preferable in chronic cases, as in the one 348 PYJ5MIA. narrated in the f Brit. Journ. of Horn/ vol. xxiv, p. 496. The only cases of acute phlebitis known to me in our literature are by Mr. Ayerst in the * Brit. Journ/ vol. xv. Lachesis seems to have been the most efficient of the several medicines used. Varicosis, while capable of considerable relief from the old medicines Pulsatilla, Silicea and Fluoric Acid, is still more effectually helped by Hamamelis. Where the external veins are affected, as in the leg, the local application of the diluted tincture is of service, while the 1st or 2nd dilution is being given internally. Before leaving the arteries and veins I must speak of pvsemia, under which heading the facts recently being brought to light regarding embolism and thrombosis will find their place. Pyaemia. The following are the conclusions arrived at by Dr. Bristowe, in his article on this disease in Rus- sell Reynolds’ c System of Medicine.’ “ 1. Pyaemia is almost invariably, if not always, preceded by some local suppuration, and this of an erysipelatous, gangrenous, or otherwise unhealthy sort. “ 2. The link between the local mischief and the constitutional infection is most frequently inflam- mation of the veins of the part affected, hut may be simply absorption of unhealthy ichor. “ 3. The local lesions which characterize pyaemia are congestions, extravasations of blood, inflamma- tory deposits, abscesses and necrosis. These are PYAEMIA. 349 generally, if not always, the result of blocking up of small arteries either by 1 emboli’ detached from the veins of the part primarily affected, or by £ thrombi ’ formed within the artery by the un- healthy blood. To the c ichorsemia * itself are due certain diffused inflammatory processes (as inflam- mation of the joints and of serous surfaces) for which arterial obstruction will not account. “ 4. The constitutional symptoms of purulent in- fection are rigors followed by sweating, a typhoid condition, quick and weak pulse, jaundice, early prostration, and generally death. The jaundice is not dependent on any appreciable affection of the liver. When the disease takes a more chronic course, the symptoms are those of hectic.’-’ I have put down these details that you may estimate the warrant I have for saying that Lachesis is the most promising remedy we have for this condition. The phenomena, local and general, which follow the serpent’s bite lead us to expect that when a local affection assumes a malignant character, and from thence proceed poisoning of the blood and prostration of the nervous energies, there Lachesis will be homoeopathic and curative. Now this is just what we have in pysemia. Experience has proved the value of the medicine in such analogous conditions as traumatic gangrene, malignant pustule, and septicaemia from dissecting wound; and the following record by Dr. C. Dunham reads very like phlebitic pyaemia itself. “ I have three times,” he w rites, “ been called to cases of chronic ulcer of the lower extremities (probably of syphilitic origin) in which the discharge had ceased, the extremity had 350 ANGIOLEUCITIS. become oedematous, and a hard, slightly red swell- ing extending up along the coarse of the principal veins—together with a great and sudden prostration of strength, low muttering delirium, and general typhoid symptoms—gave good reason for supposing that general phlebitis had occurred. In these cases a careful study of the symptoms induced me to give Lachesis. The effect was all that could be desired, the patients rallying promptly—all symp- toms of phlebitis speedily disappearing ” (‘Amer. Horn. Review,’ vol. iv, p. 110). In chronic pysemia, with hectic, the administra- tion of China would probably aid good food and wine in supporting the system through the exhaust- ing suppuration. It is to be hoped that the surgeons attached to our hospitals, and who must have had opportunities of treating pysemia, will communicate the results of their experience. Of the diseases of the lymphatics and lacteals very little is known. The scrofulous affections of the mesenteric, bronchial, and cervical glands will come before us hereafter. I must, for the sake of com- pleteness, mention Angioleucitis, though I cannot tell you how it should be treated. The only form in which I know it is where the lymphatics of the arm inflame after a poisoned wound. Aconite and Belladonna, in low dilutions and frequent doses, are good for this. The glands subservient to the circulatoi’y system 351 LEUCOCYTH.'EMIA. are, besides the lymphatic and the mesenteric al- ready mentioned, the spleen, the supra-renal cap- sules, and the thyroid. The spleen is sometimes attacked by inflamma- tion, Splenitis. China and Perrum both have a specific action upon the spleen: and considering that inflammation of this organ is nearly always of malarial origin, the former medicine would appear remarkably well suited to it. Hypertrophy of the Spleen, as a sequela of ague, is not uncommon. The medi- cines already mentioned are useful in its treatment, but Dr. Maclean’s results with the ointment of the Biniodide of Mercury* would lead me to try the internal administration of this medicine with the best hopes of success. In connexion with the lymphatic glands and the spleen, I must speak of Leucocythsemia. We have no known medicine which causes any phenomenal resemblance to this disease. Nor does Pathology help us; for she has hardly made up her mind whether the mischief begins in the blood itself, or in the blood-glands. Aitken, however, mentions two cases in which its “ origin obviously dated from inflammatory swellings of the lymphatic glands after exposure to cold and wet.” This may * See ‘Brit. Journ. of Horn./ vol. xxvi, p. 476. 352 Addison’s disease. give us a hint for the administration of Iodine, especially as he adds “ a high degree of emaciation ordinarily accompanies it.” But we want a medi- cine which shall certainly influence all the blood- glands,—the supra-renal capsules and the thyroid as well as the lymphatic glands and the spleen. The only affection of the supra-renal capsules of which we know anything is Addison’s Disease According to Dr. Wilks, there is one special form of disease of the capsules with which the bronzed skin and other phenomena described by Addison are connected. This is analogous to the scrofulous enlargements of the lymphatic glands. The asthenia and other symptoms of the malady probably depend upon the relation of the organs to the ganglionic nerves. It becomes a question, then, whether we should treat the disease symptomatically, and as a whole, in which case Arsenicum would be indicated: or whether we should endeavour to attack the “ scrofulous ” disease of the capsules as if lymphatic glands were in question, as by Calcarea and Iodine. Perhaps the Arsenite of Lime (Cal- carea Arsenica) would be useful in this disease. I have only seen one unquestionable case of it: and there neither Arsenicum nor Kreasote were of any avail to check the vomiting or to avert the fatal issue. But as the old school reports no better success, we are at least not worse off than they. As diseases of the thyroid gland I shall speak of BRONCHOCELE. 353 the simple hypertrophy which we call bronchocele* and of the curious vascular enlargement generally styled exophthalmic goitre. Bronchocele. By this name, I say, I understand simple hyper- trophy of the thyroid gland, excluding all cystic and other growths within it, which latter are the subjects of Surgery. I have already argued the liomoeopathicity of the later Iodine, and therefore of the older burnt Sponge, in its treatment. It is from these twro medicines that we, in common with the old school, obtain most benefit in goitre. Nor is it always necessary to give them in material doses for the purpose. That such doses, carefully proportioned to the state of the gland and of the patient, may be given without risk is certain, from the observations of Dr. Kidd in the Brit. Journ. of Horn., vol. xxv, p. 177. But in an earlier volume of that Journal (vol. iii, p. 439) you will find striking results recorded from Iodine 30: and in vol. xxvi, p. 670, no less satisfactory effects from medium and high dilutions of Spongia. Curiously enough, in one of the cases last referred to the burnt sponge was given in 3 grain doses of the crude powder, and with equal benefit. Perhaps, then, your best plan will be to try in the first instance high dilutions of Spongia or Iodine, with which at any rate you can do no harm : and if these fail, to administer with caution small but material doses. Should you have to seek farther for remedies, I would call your attention to 354 EXOPHTHALMIC GOITRE. the cases apparently cured by Apis in vol. xxiii of the Journal, p. 674; and to the observations on the power of the fluorides to produce goitre in vol. xxiv, p. 418. Exophthalmic Goitre, with its associated palpitation of the heart and pro- trusion of the eyeballs, is a very interesting disease. I have seen three cases of it, but in each have been hindered from some cause or other from following up the treatment. When ansemia is present, there can be no doubt of the advantage of Iron, as in the case so well recounted by Dr. Ker of Cheltenham in the Brit. Journ., vol. xxvi, p. 594. But very often no such condition of the blood obtains; and here you cannot do better than follow Dr. Kidd’s practice in the case narrated by him (vol. xxv, p. 187), and give Belladonna as he did. I am not sure that I agree with him as to the similarity between the symptoms of disease and drug: but as to the true specific relation of Belladonna to the vascular nerves at fault there cannot be a doubt. Of any diseases which may affect the thymus and pineal glands and the pituitary body I know nothing. And so I end my discussion of the cir- culatory system and its offsets. LETTER XXXIX. DISEASES OF THE URINARY ORGANS. In the present letter I enter upon the diseases of the Urinary Organs. The diseases of the Kidney will first engage our attention; and of these we shall begin with those morbid conditions of the organ with which albuminuria is associated. Before proceeding to therapeutics, however, we must agree upon certain points as regards pathology and nosology. When writing to you upon Pharma- codynamics, I used the nomenclature of renal dis- eases which we learnt together from Dr. George Johnson. I do not find that I have been led into any real misstatements thereby. But to those who adopt a later pathology than his some of my lan- guage about “desquamative” and “ non-desquama- tive ” nephritis seems hardly correct. Let us come to an understanding, then, upon the terms we shall use. There is no question raised but that (besides fatty and amyloid change) there are two distinct forms of Bright’s kidney,—the large, white, and smooth, and the small, hard, and granular. The causes and symptoms of the two varieties are as well recognised as their post-mortem appearances. Now Dr. Johnson* calls the former of these morbid conditions a “chronic * On Diseases of the Kidney. 1852. 356 DISEASES OF THE URINARY ORGANS, non-desquamative nephritis.” He states that in it the epithelial cells are not found detached after death, nor do they appear in the urine during life; and that in fact the enlargement of the gland con- sists of a real hypertrophy of its secreting structure. He considers that the disease sometimes appears in an acute form, of which he gives three instances. Hr. Dickinson,* on the other hand, maintains that the large white kidney of Bright's disease is simply the chronic form of the “acute desquamative nephritis ” which both authors recognise as the result of cold and of scarlatina. I must say that on com- paring the observations and arguments of the two writers, my judgment inclines to the side of Dr. Dickinson. Dr. Johnson’s “ non-desquamative nephritis ” must thus drop out of my nosology. His acute cases I can without difficulty refer to the category of renal congestion or ischuria: while the chronic cases he so characterises are mostly, I think, examples of amyloid disease,—when he wrote little understood. And now as to the hard, contracted kidney. Dr. Johnson styles it “chronic desquamative nephritis,” and thinks that the diminution of the size of the organ results from the shedding of its epithelial cells. Dr. Dickinson, on the other hand, considers that the mischief begins in the fibrous matrix, and that the whole process is identical with that which obtains in cirrhosis of the liver. I care less here, save as a matter of pathological interest, to make my choice between the two. Both are describing the same disease, and both recognise its most im- * On Albuminuria. 1868. NEPHRITIS. 357 portant relationship, viz. that which it bears to gout. So, though I will call it, with Dickinson, “ granular degeneration” (a name purely phenomenal), I will leave untouched the question whether it is a cirrhosis or a desquamative nephritis. You will find that the matter of treatment lies outside the sphere of dispute. I have also, in my former letters, distinguished simple acute nephritis (as from cold) from the post- scarlatinal inflammation of the kidney. As the morbid condition in the two is identical, I will include them here under the common heading Nephritis. This will therefore correspond with the “ tubal nephritis ” of Dr. Dickinson, the “ acute desquama- tive nephritis” of Dr. G. Johnson. In its recent form it is the lc acute renal dropsy,” “acute albu- minuria,” and “ post-scarlatinal dropsy ” of authors. In its chronic form it constitutes the majority of the cases in which the large white kidney of Brights disease is diagnosed or discovered. I shall best treat it by discussing the principal medicines which have been used in its treatment. Terebinthina, by general consent, stands at the head of our remedies for acute hypersemic states of the kidney. That it is, speaking generally, homoeo- pathic thereto I need not demonstrate to you. But I think it necessary to examine, with more accuracy than in my Pharmacodynamics, what is the exact condition to which it corresponds. There is a typical case of its pathogenetic effects 358 NErilRITIS. related in eh. xi of Dr. Johnson’s treatise. Besides the evidence of inflammation of the urinary passages, there was considerable haemorrhage, which the pre- sence of blood-casts of the renal tubes proved to have come from the kidneys themselves. But ob- serve that albumen was found only when blood was present, and that no desquamation of renal epithe- lium could be discovered. These are, as I have satisfied myself, the usual effects of Turpentine upon the kidney. They signify, I take it, that its main influence is expended upon the Malpighian bodies, causing their congestion, which may manifest itself in hsematuria on the one side, or in diminution even to suppression of the aqueous portion of the urine on the other. I shall have occasion to speak here- after of its supreme value in these conditions. But now as to its application to nephritis. It would be preferable according as the congestion predominated over the desquamation. This obtains, according to Dr. Dickinson, in the nephritis from cold as distin- guished from that from scarlatina. Our experience with the drug fairly corresponds with these patho- genetic indications. Dr. Kidd’s paper on Bright’s disease (Brit. Journ. of Horn. vol. xiii) first brought it prominently forward as a remedy. The first case in which he gave it was one of albuminuria of some months’ standing, with great anasarca, from cold. The urine was scanty and smoky, sp. gr. 1018 ■ under the microscope blood-globules only were observed. Com- plete recovery took place under four-drop doses of the pure spirit three times a day. The other case was apparently one of granular degeneration. But it had begun with haematuria from mechanical NEPHRITIS. 359 violence: there was much anasarca, with hvdro- thorax ; and the urine contained fibrinous casts and blood-discs. Terebinthina gtt. j ter die, removed the anasarca and hydrothorax, and the general health righted; but the urine remained albuminous and of sp. gr. 1010 only. Nor do the cases of post-scarla- tinal nephritis adduced by Drs. Henderson and Yeldham (Brit. Journ. vol. xiv, p. 1. Annals, vol. i, p. 386) lead to any different conclusion. In all the immediate effect of the Turpentine is to make the urine freer and clearer;—i. e. it liberates the Malpi- ghian capillaries from their congestive torpor, so that the aqueous portion of the urine is freely secreted, and the loaded tubes flushed of debris and cleared for action. I have already said that I myself prefer Arsenicum in this form of the disease; but I do not question the results said to have been obtained from Turpentine. Cantharis. It is generally assumed of this drug that its action is identical with that of Turpentine. But read SchrofFs experiment with it as detailed by Hr. Clotar Muller (Brit. Journ. of Horn., vol. xvii, p. 550). Besides blood, albumen, and fibrinous casts, “ epithelial cells from the renal tubes ” were observed in the sediment. Then consider the case related by Dr. Dickinson (p. 50) in which the ad- ministration of iqxxv doses of tincture of Canthari- des caused pain in the loins and increased desqua- mation, but no blood : and after death there was intense injection of the superficial capillaries, i. e. those belonging to the secreting tubes. I think there can be no doubt but that Cantharis acts more on these latter than on those of the Malpighian bodies : 360 NEPHRITIS. and is accordingly most suitable when desquamation predominates over congestion. It lias been but little used in renal disease,—its action on the bladder seeming to have been most prominent in the eyes of our therapeutists. But it deserves attention in desquamative nephritis, especially when acute. Moreover, while neither Cantharis nor Turpentine has caused the oedema characteristic of Bright's disease, the former does produce its “ head symp- toms,”—delirium, convulsions, coma : and as these usually come on some days at least after the ingestion of the poison, they are very probably secondary to the renal mischief it sets up. Arsenicum. This great medicine expends a con- siderable share of its influence upon the kidneys. In acute poisoning by it the urine is nearly always diminished or suppressed : and the presence of albumen is so constant a phenomenon that it has been assigned as a diagnostic mark between Arseni- cal poisoning and Antimonial. Then we have Dr. Mitchell's observations (New York Medical Journal, June 1865) of the repeated appearance of anasarca, with or without albuminuria, as an effect of large medicinal doses of Arsenic. Only “ a few very pale tube-casts” were here observed by the microscope. But Dr. Quaglio’s experiments, related by Dr. Cl. Muller in his paper already cited, enlarge our know- ledge on this score. He sloAvly poisoned six cats with the Arsenite of Potash, during periods of from one to ten months, and produced in all more or less completely developed Bright's disease. During life the urine was scanty, and contained albumen, fat- globules, renal epithelium, fibrin-casts, and blood- NEPHRITIS. 361 corpuscles; it was neutral in re-action, and the proportion of solids was below the standard. The animals died comatose : and after death their kidneys were found enlarged and hypersemic, and the epithe- lial cells charged with fat and granules. I should unhesitatingly have set these patho- genetic effects down to tubal nephritis but for the fact that in four out of these six cats there was found hypertrophy of the left ventricle. This Dr. Dickinson states he has never found in connexion with any other disease of the kidney but granular degeneration. While, therefore, I place Arsenicum among the remedies for Bright’s enlarged kidney, I think it must be borne in mind in relation to gra- nular and also to fatty degeneration. It is perhaps the favourite remedy in our school —it is certainly mine—in post-scarlatinal ne- phritis. In the Brit. Journ. vol. xii, p. 485, and in the Annals, vol. iii, p. 477, you will find cases of albuminuria with dropsy otherwise occasioned in which it was of the utmost service : and a very re- markable cure by it (in drop doses of the Liquor Potassse Arsenitis) is given by Dr. Henderson in vol. xiv, p. 20, of the Journal. Ascites and hydro- thorax here complicated the anasarca. The relation of Arsenic to inflammation of the serous membranes gives us another element in its homceopathicity to Bright’s disease : and indicates its employment, if not previously, at least when they occur. I must now speak very briefly of some other medicines which appear specifically related to tubular nephritis. 362 NEPHRITIS. Digitalis appears to be the favourite remedy for this disease in the old school. It is administered as a “ diuretic.” But it is generally admitted that this action on its part is very different from that of the other substances which bear the name: and is rarely if ever to be obtained in the healthy subject. Indeed, in poisoning by large doses, suppression of urine is often noticed. Chelidonium has caused very striking symptoms of desquamative nephritis. Besides the general phenomena of renal irritation, an examination of the urine in one case shewed the presence of cylin- drical casts with epithelial cells. The mischief in this case was so considerable that cedematous swell- ings of the extremities occurred. The relation of Chelidonium to pneumonia here becomes import- ant, because of the frequent occurrence of this in- flammation as a complication of tubal nephritis in children. Dr. Buchmarm gives one case of cure of chronic renal disease by this medicine: but it was treated at a distance, and too imperfectly described for identification. Ferrum, especially in the form of the tincture of the muriate, is universally recommended in ne- phritis, when the acute symptoms have subsided. Dr. Johnson’s own caution indicates the homoeo- pathicity of its action here. “ If,” he writes, “ the urine becomes more scanty or more deeply-coloured and albuminous after the use of the steel, it may be necessary to suspend it for a time, or to give it in smaller doses.” In a discussion on a paper on the action of Iron at the British Homoeopathic So- ciety, Dr. Metcalfe mentioned a case in which GRANULAR DEGENERATION. 363 symptoms very like those of acute ursemia followed a single overdose of Iron, and subsided upon its elimination in the urine. Of some of the complications of this form of Bright’s disease I have already spoken under Can- tharis, Arsenicum, and Chelidonium. I have only to add that for the vomiting Kreasote would pro- bably prove the best remedy. Granular Degeneration is a very serious matter. Dr. Kidd, though ascrib- ing benefit to the use of Nitric Acid, and—as in the case mentioned—to Turpentine, acknowledges its ultimate fatality in nearly all cases. I think our most hopeful outlook is in the direction of Plumbum. So frequent is granular kidney the result of plumbism, that in 26 out of 42 workers with lead, dying from various causes in St. George’s Hospital, this lesion was discovered post- mortem (Dickinson). Cachexia and degeneration of tissue are characteristic of lead-poisoning, and in such conditions it has always been a valued remedy in our hands. Nor does the supposed intermedi- ary development of gout impair the significance of the fact. Dr. George Moore, after a most tho- rough examination of the question, arrives at a verdict of “ not proven ” as to the causation of true gout or rheumatism by lead (Brit. Journ. of Horn., vol. xxiv). And it is admitted that in many instances the granular kidney is the only gouty manifestation present in these subjects. I should prescribe, therefore, a lengthened administration of 364 GRANULAR DEGENERATION. Plumbum to all gouty persons—not lead-workers— in whom symptoms of renal degeneration began to appear. But what if this variety result from lead itself, or from valvular disease of the heart, or as a sequel to the albuminuria of pregnancy. In these cases I would direct attention to Colchicum. There is little doubt of this medicine exerting a specific action upon the kidney, showing itself sometimes by increase, sometimes by diminution of the urinary water, but always by a decrease in the elimination of the organic solids (Bocher). Such is the condition Ave have before us. The certain, though unexplained, relation of Colchicum to gout confirms the indications for its selection. You will remember, moreover, what I have said about the possible relation of Arsenicum to this form of Bright’s disease. Of the complications of granular kidney the car- diac hypertrophy need not be mentioned, as it is a compensatory change. The bronchitis which so frequently occurs would hardly call for Aconite: I have already suggested that this is probably the form of bronchial inflammation caused by Mercu- rius corrosivus. For pericarditis occurring in these patients I should depend upon Colchicum, or Arse- nicum if the effusion be great. The dim sight of which they often complain appears to consist in a serous infiltration of the retina, with extravasations into its substance, and thickening of its connective tissue. It is not a hopeful condition: and for this, with the atheroma, the tendency to haemor- rhage, the cachexia, and the depression of spirits, I could only rely on such a medicine as Plumbum AMYLOID DEGENERATION 365 which covers the central mischief. For the dys- pepsia, if accompanied with much slimy mucus about the fauces, Dr. Kidd recommends Nitric Acid. Vomiting probably gets rid of some of the urea: but if it is excessive, Kreasote might help. When ursemic symptoms set in Opium is the only medicine from which much help can be expected: * but you will do well to aid it by setting the skin to work by a hot-air bath. Of the general treatment of these cases I have nothing to say in addition to what has already been said by Drs. Johnson and Dickinson. The facts brought forward by the latter writer as to the influence of climate are very important. For my- self, were I the subject of this disease, I would place abandonment of the British Islands as the first item in my treatment. Amyloid Degeneration of the kidneys—of old styled waxy or lardaceous, and by Dr. Dickinson (upon a hypothesis of its causation) named “ depurative infiltration ”—ap- pears to be in all cases the result of a drain upon the system, especially of pus. In seeking for a remedy to suggest, I have come upon Phosphoric Acid as promising most. This medicine has well- known virtues in the hectic of the suppuration from phthisical lungs and carious bones : it might also remedy the more remote consequence now * Dr. Drury declares it to be often of striking efficacy. Dr. G. Schmid recommends Cuprum Aceticum, and Dr. Marcy Cannabis Indica. 366 FATTY DEGENERATION. before us. Its close relative, Nitric Acid, has cured the same degeneration in the liver, and Phosphoric Acid has an affinity almost equal for the kidney, as we shall see farther on. Dr. Dickinson also notes the constant diminution of Phosphoric Acid in the urine in this disease. The pulmonary complications of this amyloid de- generation probably call for the same treatment as those of tubal nephritis. The oedema and diarrhoea ought not to divert our attention from the main current of the treatment. Fatty Degeneration is a not uncommon accompaniment of the last- named, and indeed of every form of albuminuric disease. Correspondingly it has been caused and may be cured by Arsenicum. But whenever it presents itself, as in the cases described by Dr. G. Johnson, as an idiopathic and substantive affection, I would direct your attention to Phosphorus. You already know the relation of this medicine to fatty change as such; aud a case of poisoning by it re- corded by Dr. Hempel well shows its specific affi- nity for the kidneys.* In this connexion it is interesting to note that in one of Dr. Johnson’s cases the affection (which came on in three weeks’ time) appeared to be the immediate result of sexual excess. Moreover, fatty degeneration of the kid- * The face was swollen: the urine scanty, high-coloured and frothy, containing albumen and exudation cells : amaurosis occurred. After death the kidneys were found congested and the uriniferous tubes blocked up. FATTY DEGENERATION. 367 neys has been observed in connexion with acute yellow atrophy of the liver; and the homoeopathi- city of the symptoms of Phosphorus poisoning to those of this malady has been attested by Frerichs himself. Besides, the references already made, I may men- tion in connexion with renal disease and dropsy a paper by Mr. Pope in vol. xvi and another by Dr. Atkin in vol. xvii of the c British Journal of Ho- moeopathy/ and one by Dr. Gibbs Blake in vol. iii of the ‘ Annals/ LETTER XL. diseases of the uiiinary organs (continued). In my last letter I spoke of those conditions of the kidney with which albuminuria was associated. A few additional remarks upon this symptom in its more general relations will bring us to those mala- dies, obviously renal, but really in most instances lying farther back than those organs through wdiich they manifest themselves to our observation. These are Chylous Urine, Diabetes, Gravel, and Azoturia. Albuminuria. That this condition may exist prior to, or even in- dependently of, renal disease is unquestionable. You cannot read a better defence of this position than Dr. Meyhoffer’s papers in the Monthly Horn. Review for 1866-7. Claude Bernard’s experiment, by Avhich irritation of the nervous centres induced albuminuria as well as glycosuria, hints the frequent neurotic origin of such cases. Phosphoric Acid and Helonin will then claim your attention. One of Dr. Mey- hoffer’s cases, and another in Hempel sub voce, will illustrate the action of the former: of that of the latter you will find evidence iu the article on it in Dr. Hale’s book. DIABETES. 369 Chylous Urine is rarely seen in this country. Dr. Chapman, men- tioning the value of Phosphoric Acid in nutritive derangements of children accompanied with a milky state of the urine,* suggests the use of this remedy in the “chylous urine” of the West Indies. If now you will read Dr. Lionel Beale’s account of the constitutional symptoms of this disease, as ob- served by him in several cases,f you cannot fail to see Dr. Chapman’s recommendation confirmed, and the homoeopathicity of Phosphoric Acid to the whole condition established. Uva ursi, also, has some evidence in its favour (see Brit. Journ. of Horn., vol. iv. p. 420). Diabetes. The dietetic treatment of diabetes must always be of high importance. But it is not, in the nature of the case, and by the confession of its advocates, curative. Sometimes indeed under its use Nature, relieved of much of her burden, asserts her recu- perative power, and when the patient returns to his usual regimen, he finds it unattended by its pristine consequence. But too often the diabetic regimen proves but a continuous and most irksome palliative; the least abatement of its rigid restrictions is followed by an increase of the malady, and the patient at length succumbs under pulmonary disease, carbuncle, or * ‘ Brit. Journ. of Horn.,’ vol. vii, p. 391. f ‘ Brit. Med. Journal’ for 1860, p. 772. 370 DIABETES. simple exhaustion of the powers of life. Until we can do more than cut off the supplies,—until we can attack the morbid process, we cannot consider ourselves in a position to cure diabetes. In a paper on this disease in vol. xxiv of the Brit. Journ. of Horn., I have endeavoured to esti- mate our resources for effecting this end. Traditional medicine has given us nothing but Opium and Kreasote. The former is confessedly only palliative; and though the virtues of the latter are dynamic if any at all, they are in this disease rare and uncertain. Homoeopathy on the one hand reports decided benefit in diabetic cases from general and symptom- atic treatment, as by Arsenicum, Nux vomica, Cal- carea phosphorica, and such like. On the other hand it reports certain complete or proximate cures with medicines presumably homoeopathic to the essen- tial lesion. Referring you to my paper for informa- tion as to Natrum sulphuricum and Asclepias vince- toxicum, I desire to concentrate your attention here on Phosphoric Acid and the Nitrate of Uranium. Acidurn Phosphoricum stands at present unques- tionably in the highest place among the remedies for diabetes. The first notice of it is contained in the 16th vol. of the British Journal. Three very in- teresting cases are there recorded by the late Dr. Walker of Manchester, of which the following is a summary. Case 1 is briefly told : sugar was present in the urine, Avith the usual symptoms; improvement ensued, and the disease Avas for some time kept at bay by Phosphoric Acid and the saccharated (!) carbonate of iron (quantities not stated) but the DIABETES. 371 patient eventually sank under pulmonary disease. Case 2 was equally well-marked; the patient was put upon rigid diet, and took three times a day a dessert-spoonful of a solution of 14 grains of anhydrous Phosphoric Acid in 6 oz. of water. The sugar and the general symptoms soon disappeared; and when, six months after, the patient returned to his usual diet, he felt no ill effects; he was cured. In Case 3 the Phosphoric Acid was given in the same manner ; but the diet wras unrestricted. The sp. gr. of the urine fell in eight days of this treat- ment from 1035° to 1023°. The ultimate issue of the case is not recorded.—Next, in vol. xix of the same Journal, Dr. Hansford contributes two cases in which Phosphoric Acid was the main remedy,— in the first in the 6th dilution, in the second in grain doses of the anhydrous acid. The usual restrictions were put upon the diet. In both the sugar disap- peared from the urine, and the patient got well.— Two other cases are cited in my paper in which the disease wras kept at bay or nearly cured by the medicine. What is the rationale of this unquestionably curative action of Phosphoric Acid ? It cannot be other than dynamic, for it is exerted in all dilutions, though more markedly in the lowest. Whether it is homoeopathic or not, the proving contained in the ‘ Chronic Diseases3 does not enable us to say. But it deserves to be noted that Dr. Pavy found saccharine urine to result from the injection of Phosphoric Acid into the general venous system, and also from its introduction into the intestinal canal (On Diabetes, p. 82). He considers the acidity of the drug to 372 DIABETES. have caused the phenomenon; but he did not try •whether other acids would produce the same effect. In estimating the claims of Phosphoric Acid to be a remedy for diabetes, we must not forget its power- ful action on the nervous centres, in whose derange- ment the disease often essentially consists. Uranium Nitricum has even higher claims on our attention. In the Brit, and For. Medico-Chirurgi- cal Review for 1857, it is stated, as the result of some experiments by M. Lecomte, that the gradual poisoning of dogs with small doses of Nitrate of Uranium invariably caused the urine to become saccharine. This fact, curious only in the eyes of an alioeopathic reader, was to a homoeopath pregnant with suggestiveness. Its import was first pointed out by Dr. Bradford, of America, in the ‘ North American Journal of Homoeopathy.’ The earliest cases, however, were supplied by Dr. E. M. Hale, in the No. of the same Journal for Nov. 1861. Unfortunately no examination was made of the urine ; but the symptoms were those of genuine dia- betes. Of the three cases, two were cured, and one greatly ameliorated. I have given a resume of these cases in my paper, and have followed them with three from my own practice. In the first, the sp. gr. of the morning urine was reduced under five weeks of the Uranium from 1042° to 1025°; and this with- out change of diet, which had previously been restricted. I have since seen this patient about, and he looks thriving: but I have had no profes- sional intercourse with him. In the second, an old man, dieting and Nitrate of Uranium reduced the sp. gr. in a fortnight from 1035° to 1019° : and he DIABETES. 373 became and continues free from all diabetic symp- toms. The third case, up to the end of the report, was a brilliant one. In four months’ treatment he gained thirteen pounds in weight, improving corres- pondingly in health and strength. The urine had fallen from six pints daily to three, and its sp. gr. from 1035° to 1022-8°; but it still contained some sugar. Much to my disappointment, I heard that this gentleman, of whom I had lost sight since Feb. 1866, had died of acute pulmonary disease. I have had no cases of diabetes under my care since I wrote the paper above cited. But Dr. Drysdale (Brit. Journ. of Horn. vol. xxv, p. 597) has spoken of obtaining great benefit from the Uranium in this disease: and Dr. Eugene Curie, of Paris, has published three cases in the Bull, de la Soc. Med. Horn, de France corroborative of its value. One was cured : and in the other two the quantity of sugar in the urine was reduced to one half. Another, from an American source, you may read in vol. xxvi of the Brit. Journal, p. 661. During the present year, however, Mr. Edward Blake, of Wolverhampton—worthy scion of a worthy bouse—has been publishing in the same Journal a series of experiments with the Nitrate of Uranium on both men and animals. In none of these was sugar eliminated by the urine, and the only con- stant post-mortem appearance in the animals was ulceration of the stomach and duodenum. Mr. Blake’s comments on the results he has obtained are “ 1st. That the Nitrate of Uranium will not -cause the urine to become saccharine. 374 POLYURIA. “2nd. That the Nitrate of Uranium exerts a specific action on the circulation of the stomach and duodenum resembling that of Kali bichromi- cum and Arsenicum. “ 3rd. That that action, which is usually ulcera- tive, is displayed to the most marked degree in the neighbourhood of the pylorus. “ If the power of producing glycosuria be denied to this drug, it will be asked ‘ How, then, can the success of the Uranium treatment be explained ?’ I think it must be attributed to the homoeopathic rapport which exists between the pathogenesis of Nitrate of Uranium and the digestive symptoms so commonly seen in the diabetic.” As a remedy for Polyuria, the so-called “ diabetes insipidus,” you will natu- rally seek to medicines of the order “ diuretics.” Of these Scilla deserves your best attention. The first case in which I gave it was an Indian officer, who had for two years been passing an inordinate quantity of pale urine. There were no special symptoms present, but the drain seemed to keep his health and strength below par. Phosphoric Acid, which I first gave, did no good. He then got Scilla 2, three drops in water twice daily. After taking this for three or four weeks, he re- ported that the urine had fallen to its normal amount, and that he was feeling quite well. 1 have since given it in a similar case with equally good results. GRAVEL. 375 Gravel. It is necessary to have clear ideas about the various morbid states included under this term. I will divide them into four groups. 1. There may be actual excess of lithic or phos- phoric acid formed in the system, and eliminated by the urine. This is indeed rare, especially as regards phosphoric acid. Excess of lithic acid is of course characteristic of the gouty diathesis: and I have already told you what we can do to modify this. The only additional question raised by this manifestation of the diathesis is that of giving alka- lies. I cannot think that we should refuse the temporary aid of these remedies when we have reason to apprehend concretion. Excess of phos- phoric acid implies waste of nervous tissue (more, rarely disease of bone, as mollifies ossium). Its best medicine would probably be Phosphoric Acid itself in the dynamized form. 2. There may be deposit, without excess, of lithic acid or lithates on the one hand, or phos- phates on the other. They arise, as you know, the one from a too acid, the other from a too alkaline urine. Again there can be no objection that I can see to redressing temporarily the balance of an over-acid urine by chemical measures. But you will be too wise to expect its radical cure from anything but proper diet and mode of living. In this category you will consider the regulated use of Lemon-juice, of whose value Dr. Kidd has fur- nished so many striking illustrations (Brit. Journ. 376 GRAVEL. of Horn., vol. xxi, p. 43). Deposit of lithates is generally connected with some temporary derange- ment of health, and here requires no special treat- ment. Its occurrence in a permanent form, as one of a group of symptoms pointing to digestive de- rangement, I have always found an indication for Lycopodium. If, however, the symptoms be rather neuralgic, the presence of abundant lithates leads me to Quinine. I cannot explain why it is so : but I give it you as a bit of experience.—Alkaline urine, when secreted so by the kidney, must de- pend upon a depressed state of the general, especi- ally the nervous, system. Phosphoric Acid is here again likely to help as a medicine; and if you like to give it in material doses so as to obtain its che- mical as well as its dynamic effects I at least shall not quarrel with you. But I apprehend that alka- line urine is most frequently the result of inflam- mation of some part of the urinary mucous tract, and requires the treatment proper thereto. 3. I suppose that the use of nitro-muriatic acid in oxaluria is one of the most satisfactory bits of the ordinary practice. What is the rationale of its action ? There is no alkaline condition here to be chemically neutralized; indeed, the alliances of the oxalic are rather with the lithic than the plios- pliatie diathesis, as Dr. Bence Jones has demon- strated. I suspect that the nitro-muriatic acid is a tertium quid different either from the nitric or the muriatic : and that its action in oxaluria is specific and dynamic. I must add, however, that—upon the analogy of the usefulness of Phosphoric Acid in the phosphatic diathesis— I gave Oxalic Acid AZOTURIA. 377 itself, in the 12th dilution, to a case of this kind, and with very satisfactory results. 4. When, in connexion with any of the causes and varieties of gravel, renal calculi are formed, the case is passing into the region of chemistry or sur- gery. Your general and medicinal means may indeed still check their multiplication or increase. If pain accompanies their passage down the ureter, Dr. Beakley tells us that five-drop doses of Cha- momilla 1 frequently repeated will relieve : hut I should be prepared with the inhalation of chloro- form in the very probable event of its failure. Azoturia —i. e. excess of urea in the urine—you are hardly likely often to encounter. If you should do so, you will read with interest Dr. Drysdale’s case in vol. xxv of the Brit. Journal, in which, after the failure of remedies symptomatically selected, Senna (j>, four drops twice a day, was given with marked benefit. Dr. Drysdale was led to this medicine by the statement in Cl. Muller’s paper that Senna invariably causes in healthy persons an increase in the amount of urea, chloride of sodium, earthy phosphates, and urates in the urine, the specific gra- vity of which is consequently increased. You may also consider what has been said of Causticum (Pharmacodynamics, p. 205), though I do not know that urea formed part of the undue tissue waste it has been found to rectify. LETTER XLI. diseases of the urinary organs (continued). I have hitherto been speaking of disorders in which renal mischief is but one, however import- ant, element. But I must now tell you what we can do when the kidney itself is primarily and solely affected. Renal Congestion, though not mentioned in our systematic treatises, I take to be no uncommon malady. I do not mean their chronic and mechanical engorgement, as from valvular disease or pregnancy; but an acute hypersemia of the glands, short of inflammation, caused by cold. Here, as you might expect, Tere- binthina is an almost infallible remedy. I have always given the 3rd dec. dilution. The condition just mentioned probably lies at the bottom of Suppression of Urine, and we accordingly have a case cured by Dr. Yeld- ham with Terebinthina 1, in which no urine had been passed for four days (Annals, I, p. 386). Sup- pression of urine has also been observed in cases of HSEMATURIA, 379 poisoning by Mercurius corrosivus, Arsenic, and Kali bichromicum; so we have some medicines to fall back upon, should Turpentine disappoint us. The last named is said to have been beneficial in the ischuria which follows Asiatic cholera, whose association with absence of the biliary secretion suggests its dependence upon drain of fluid from the blood rather than direct action of the poison upon the glands. Hsematuria is often another manifestation of renal congestion, and Terebinthina is nearly always serviceable in its treatment. If it be a part of general purpura, you will of course treat it on the principles laid down when speaking of that disease. I cannot say whether Arnica is of service when bloody urine depends, as it frequently does, upon mechanical disturbance of renal calculi. In the so-called “in- termittent haematuria” no blood whatever is pre- sent, according to Dr. Lionel Beale.* Dr. Trinks has recorded a case (Annals, vol. iii, p. 228) in which hsematuria was the prominent symptom of post-scarlatinal nephritis. As anaemia was already resulting, he gave China 1st dec., three drops every four hours, with the result of rapid disappearance of both local and general symptoms. Haematuria from disease of the bladder requires the treatment of the disease it complicates. Its presence, however, is in chronic cases an indication for Ferrurn Muriaticum : and, when acute, it calls * See the ‘ Practitioner * for Aug., 1868. 380 PYELITIS. for Hamamelis or Millefolium, besides the local measures in which I need not instruct you. Under the heading Pyelitis I will now speak of the forms of suppurative ne- phritis, which nearly always begin in the medullary portion and the pelvis of the kidney. A large number of them are either secondary to bladder disease, or they manifest their existence largely by symptoms of distress of that organ. Sir B. Brodie has given a capital account of these cases. He be- lieves that they often arise from “an injudicious use of large doses of copaiva and cubebs, especially the latter ■ ” and that it is here, and not in simple catarrh of the bladder, that uva ursi and buchu exert the influence which has given them repute in urinary disorders. He also recommends the Tinct. Ferri Mu- riatis. These hints may be of service to us. The Uva ursi and the Ferrum Muriaticum promise most: and the former has cured a case of the kind. Nor can I suggest anything better when pyelitis arises from mechanical violence or from the irrita- tion of calculi. If there is drain of pus from the kidney, you will of course keep your patient up by China. Of cancer and tubercle of the kidney, in their therapeutical aspects, I have nothing to say : and so we will pass on to the urinary passages, which we have already approached when speaking of pye- litis. Let us take first the diseases of the bladder. IRRITABLE BLADDER. 381 Cystitis, in its acute form, is rarely met with. When oc- curring as a metastasis of gonorrhoea, it must be treated with Cantharis; and the constitutional ir- ritation will generally require the alternation there- with of Aconite. When resulting, as it sometimes does, from local damp, Dulcamara is even better than Cantharis. Chronic cystitis—catarrh of the bladder—is common enough, though generally se- condary to stricture, stone, diseased prostate, &c. You are not the less to apply to it your specific remedies, while of course you will not neglect the treatment appropriate to the primary affection. Here again Cantharis takes the first place, but Cannabis saliva closely treads upon its heels. The clogging of the catheter with mucus described by Morgagni in poisoning by the latter drug is just what is often observed in this malady. The Chi- maphila umbellata is another medicine specifically applicable to this condition, especially wdien occur- ring in women. The remedies used in old-school practice for chronic cystitis—notably pareira brava, turpentine, and cubebs—are almost confessedly homoeopathic thereto ; and you may bear them in mind in the event of your having to go beyond the medicines commonly used by Homoeopathic physicians. Irritable Bladder, without inflammation, is often a symptom of gout, when Nux vomica may relieve it. If it be a 382 IRRITABLE BLADDER. simple hypersesthesia, you will generally get good results from a persevering use of Belladonna. But if the irritability be diurnal only—indicating a localization in the inferior portion of the bladder,— and without spasm, Ferrum is specific. The pre- cisionising involved in this last bit of practice we owe to Dr: Robert Cooper of Southampton (Annals, vol. v, p. 399).* You must remember that irrita- bility of the bladder sometimes arises from disease remotely seated,—as in the kidney, the uterus, or the rectum : or from an irritating quality of the urine. * His cases are peculiarly instructive. The first was “ a light- haired, pale complexioned, delicate little girl,” who had been suffering for two weeks from “incontinence of urine, coming on nearly every half-hour, sometimes Softener, but only in the day- time, and invariably ceasing on her retiring to bed at night, and when lying down during the day.” She had been taking much alloeopathic medicine, chiefly Iron. After Podophyllum had been taken for three days without avail, Dr. Cooper, suspecting that the Iron had caused the trouble, gave Arsenicum as an antidote, and in less than a week no trace remained of her distressing malady. Then the brother of the little girl, two or three months afterwards, was afflicted in a precisely similar manner: and as there was with him no antecedent history of pernicious medication, he got Ferrum Phosphoricum 1 with speedy and complete success. The next case was of a woman, set. 65, a teetotaller: her symptoms were aggravated after drinking tea. The same medicine and dose cured in a few days: the trouble had lasted six months. The fourth case was after parturition, and the vesical disorder was accompanied with metrorrhagia and a sense of hearing down and weakness in the hypogastrium. All the symptoms disappeared in a few days under the Iron. In these cases the phosphate was given; but in a fifth the acetate acted equally well, and in the 6th dilution. In the sixth case—a man—the phosphate was again successfully prescribed: it seemed to him as if any fluid he took went right through him ten minutes after. RETENTION OF URINE. 383 Strangury. By this term (of which dysuria is a practical equivalent) I mean frequent, difficult, and painful micturition,—a small quantity only being passed at a time. It is, I suppose, an affection of the neck of the bladder, and may be either nervous or inflam- matory. When it occurs in an acute form—and I know few seizures more painful—do not care to in- quire to which of these categories it belongs, but give your patient repeated doses of Camphor, and I promise you that you will earn his grateful thanks. The same treatment is applicable when absorption of cantharides from blister is the cause of the symptoms. In cases of less urgency, you will with advantage discriminate between the inflammatory and the nervous variety. In the former, you can hardly do better than give Cantharis itself, if your patient be of the male sex. But if the dysuria occur, as it very often does, in a woman, I commend to you Copaiba and the Eupatorium purpureum. The cases in which I have seen the former act so well have all been women advanced in life : but I do not know that it has any special suitability to these. In nervous dysuria you will find Belladonna, in the 1st dilution, a rarely-failing remedy. If you should want another, you may try Apis. Retention of Urine may be either spasmodic or paralytic. The former variety will come under our notice in connexion 384 CANCER OF THE BLADDER. with stricture of the urethra. The latter is a true paralysis of the bladder. When occurring idiopathi- cally, as in a case described by Sir B. Brodie (Lectures on the Urinary Organs, 4th Ed. p. 101) Opium ought to be its remedy ; and the same medi- cine might help the catheter to prevent accumulation of urine in typhus. When paralysis of the bladder occurs in connexion with disease or injury of the spine it might be thought that little could be done for it. But I have seen power return, and ammo- niacal urine become healthy, in a case of this kind under drop doses of the Tincture of the Muriate of Iron. Hysterical retention is of this character: and while I concur in the desire not to use the catheter for it if possible, I cannot suggest any medicine capable of supplying the instrument’s place. Stone in the Bladder calls for our medicines only to diminish the inflam- mation it sets up : and of these I have spoken under Cystitis. Cancer of the Bladder is hardly likely to be touched by anything you can do for it: but the haemorrhage to which it gives rise may be checked by Ferrum Muriaticum. Passing now from the bladder to the urethra, and reserving gonorrhoea and gleet for the diseases of the male sexual organs,, I shall have to speak of STRICTURE. 385 Stricture. You may think that I am here presuming upon the province of Surgery: but it is not so. Let me cite Sir B. Brodie’s sketch of the usual history of these cases. “ The patient voids his urine in a diminished stream. The diminution gradually in- creases, being sometimes attended with a slight mucous or muco-purulent discharge. By-and-bye there is a complete retention of urine. This sub- sides spontaneously, or is relieved by art. After an interval, which may vary from weeks to months, or even to years, he is overtaken by another attack of retention. During the whole of this time the stream of urine continues to become smaller; it is flattened, or otherwise altered in shape, or divided into two. At last the urine never flows in a stream larger than a thread, nor without great effort and striving.” Now there are three stages in this melancholy pro- gress in which our medicines will render effectual help. 1. The first is in the attack of retention, when the stricture is narrowed by spasm or inflammation, or both. When pure spasm is present, it will gene- rally yield with great rapidity to repeated doses of Camphor. When inflammation predominates or complicates, as from gonorrhoea or irritating injec- tions, you may depend with equal confidence upon Aconite. With these medicines, and the warm bath, you will seldom need the catheter. 2. I think there is no doubt but that the inci- pient symptoms of organic stricture of the urethra may be in many cases abolished by the administra- 386 STRICTURE. tion of Clematis. I have given you the evidence for this statement when speaking of the medicine in question in my letters on Pharmacodynamics.* 3. When organic stricture has become confirmed, so that mechanical dilatation is indispensable, Dr. Yeldham testifies to the great advantage of having such medicines as Aconite and Cantharis to control all inflammatory and spasmodic tendencies prior to the introduction of instruments. Aconite, more- over, administered after their passage, has been found to prevent the sometimes perilous rigor which in susceptible persons follows the operation. The surgical diseases of the prostate, i. e. the mechanical consequences of its enlargement, belong to those of the urinary organs. But physiologically the gland is a part of the male sexual system: and its only disorder which is under medical control— viz. inflammation—rarely occurs save in connexion with gonorrhoea. So I will speak of it in my next letter. * See also * Brit. Journ. of Horn.,’ vol. xxiv, p. 689. LETTER XLII. DISEASES OP THE MALE SEXUAL ORGANS. In the present letter I shall begin, if I do not finish, the consideration of the maladies affecting the male sexual organs, including those of the tes- ticle, the spermatic cord, the prostate gland, and the penis and scrotum. Of the diseases of the testis I shall speak first of Orchitis. We are most familiar with this disease when oc- curring secondarily to gonorrhoea. In these cases it seems to be the epididymis on which the stress of the mischief falls: while in orchitis from cold, from sexual excess, or from mumps, the body of the gland is mainly affected. Whether there should he a cor- responding difference in the treatment,—whether the testis and epididymis are as distinct pathologically as the cortical structure and the pelvis of the kidneys, I cannot say.* In my own experience Pulsatilla, with Aconite, has given me every satisfaction alike in the orchitis of gonorrhoea and in that of mumps : and it appears to be the general favourite. Clematis is its only rival : and although its efficacy has been ques- * Parenchymatous orchitis is generally more painful than epididymitis, especially if the tunica albuginea is involved: and would hence require more Aconite. 388 SARCOCELE. tioned (see HempeFs Mat. Med. vol. ii, p. 511), there is a case of Dr. Ransford’sin the Brit. Journ. of Horn, vol. xxv, p. 659, in which no medicine could have acted better. Spongia has some evidence in its favour. Its symptoms point to irritation of the tunica vaginalis and spermatic cord rather than of the body of the gland. I have never employed ice or compression in this disease; nor do I think either necessary : but there is of course nothing to forbid them. Sarcocele is a term including every variety of solid enlarge- ment of tlie testis. Where the tumour is carcino- matous, enchondromatous, cystic, or fibro-plastic it hardly comes within the range of Medicine : and any interference must be in the way of castration. Simple, strumous, and syphilitic sarcocele are the varieties of the disease of whose treatment I shall speak. 1. Simple sarcocele means chronic orchitis, with induration. The medicines I have already men- tioned in connexion with acute orchitis—Pulsatilla, Clematis, and Spo?igia—have occasionally proved useful here. But two important additions to their number are Aurum and Rhododendron. I have myself seen the best effects from Aurum. Dr. Yeldham considers it specially applicable when the cord is palpably enlarged, and is affected with neural- gic pains. Rhododendron, like Spongia, seems to act mainly if not entirely on the tunica vaginalis: as you will see in its proving, and in the cases cured by it. NEURALGIA TESTIS. 389 2. Strumous sarcocele may be either chronic orchitis in a patient having this diathesis, or actual tubercular deposit,—the latter generally in the epididymis. In the former Spongia—and perhaps Iodine itself—would bid fair to be useful. In the latter a general anti-scrofulous treatment, medicinal and hygienic, would probably give the best results. 3. To the usual remedies for syphilitic sarcocele, Mercury and Iodide of Potassium, we have Aurum to add. Irritable Testicle is so often a symptom of other mischief, as varico- cele, disease of the prostate or prostatic urethra ; or a result of improperly-regulated sexual functions,— that its treatment is usually “ tolle causam.” Igna- tia ought to be a useful medicine. Neuralgia Testis may be said to exist, when, without or besides mor- bid sensibility of the gland, paroxysms of sharp pain occur from time to time. Aurum is usually recom- mended for it: but I would direct your attention to the proving of Hamamelis by Dr. Burt in vol. xxiv of the Brit. Journ. of Horn., p. 610. Pull doses of the fluid extract of this drug gave him such excruciating pain in the testicles that he was com- pelled to discontinue the proving. He has only hitherto made use of this pathogenetic fact in the treatment of ovarian neuralgia : but I have myself given Hamamelis in a case of neuralgia, with heat 390 IMPOTENCY. and morbid sensibility, of the testicles with very satisfactory results. Colocynth, also, deserves con- sideration (see Mr. Pope’s remarks in the Monthly Horn. Review, Dec. 1868, p. 733). Impotency. In undertaking the treatment of a case of this kind, you will of course begin by ascertaining whether your patient has any discoverable disease of the testis or cord, or of the kidney; whether he is dyspeptic, or has oxaluria; and whether it is moral treatment rather than medical which is re- quired. When these causes of impotencv have been eliminated, there remain three others to which his trouble may be traced, and which require treat- ment accordingly. 1. The fault in many instances is in the nervous centres. Sometimes the sexual weakness is one element in general paralysis, especially locomotor ataxy. Sometimes there is a history of a blow or fall, when you will think of Arnica or Hypericum. You will observe cases of this variety, moreover, in which the loss of power is not in the testicles, but in the ejaculatory, erectile, and intromittent func- tions. This, which is a true paralysis, has been caused and may be cured by Arsenic. In some cases of conjoined sexual atony and cerebral de- pression Kali bromidum might prove useful. 2. Impotency may be the result of over-indul- gence of the sexual functions, in which event it is usually complicated with spermatorrhoea (q. v.). Rest to the exhausted organs, and the administration SPERMATORRHOEA. 391 of Phosphorus and Phosphoric Acid, are the remedies. 3. A premature senility, or a sort of general eunuchism with or without atrophy of the testicles, may be the condition of the patient who consults you for impotency. Baryta carbonica is good here : and Coniurn is so homoeopathic that it ought to be of service. The same may be said of Agnus castus, which Stapf states that he has several times used with success in impotence. Perhaps Camphor should be added to the list. Sterility in the male subject—i.e. capacity for sexual inter- course but inability to procreate—so generally depends upon organic causes that it rarely comes within the reach of medicine. If it be associated with atrophy of the testicles, the medicines capable of causing this atrophy, viz. Iodine and Conium, might be tried. Spermatorrhoea. We owe to Lallemand the demonstration of the frequent dependence of this trouble upon chronic inflammation of the prostatic portion of the urethra, with the seminal ducts and vesicles, and the pros- tate. But we are not, I think, to follow him in the treatment of such cases by the local application of nitrate of silver,—roughly homoeopathic though it be.* We shall accomplish the same end by our * A milder local treatment is advocated by Dr. Yaughan-Hughes 392 SPERM ATORItHCEA. internal medicines, which by elective affinity seek out and influence the affected part. The chief of these are Cantharis and Staphysagria. Dr. Kidd speaks highly of the former: * and I have myself seen great benefit result from the latter. Excluding the comparatively rare instances in which spermatorrhoea results from rectal irritation, which must be treated with reference to the latter region; and from suppressed cutaneous eruptions, where Sulphur is required, the only other form of spermatorrhoea we have to combat is the atonic, from masturbation or sexual excess. Hahnemann and his immediate followers, as Hartmann, consider China specific in this condition. It would suit the condition of morbid irritability in which it com- mences admirably. “ The frequent and morbid excitement of the sexual organs, resulting in an involuntary emission of semen, and caused even by slight abdominal irritations, is permanently relieved by Cinchona : ” so writes Hahnemann. Later on Phosphorus and Phosphoric Acid become our most suitable medicines : and, in alternate use and varying dilutions, will be found very serviceable. I must confess, however, that the after-effects of long-continued masturbation are not easy to re- move. Perhaps the habit is seldom entirely broken off. in a paper on this disease, under the title of “ The Irritable Pros- tate,” in vol. v of the ‘ Annals.’ You will weigh his recommenda- tions in unusually obstinate cases. * ‘ Annals/ vol. v, p. 131. VARICOCELE. 393 Hydrocele, in its common vaginal form, has not unfrequently been cured by Homoeopathic remedies. “Acute hydrocele,” i.e. inflammation of the tunica vaginalis independently of the other contents of the scrotum, would probably find its best remedy in Sponyia. But chronic hydrocele is rather a serous dropsy. Pulsatilla, Rhododendron, and Aururn are again the medicines which have done the good service to the testicle: but Graphites is to be added. Cases illustrative of the action of Pulsatilla and Graphites by Dr. Black may be read in the ‘ Brit. Journ. of Horn./ vol. vii, p. 525, and there is a case cured by Rhododendron by Dr. Hastings in the same Journal, vol. xviii. p. 351. I have myself seen a hydrocele disappear under Aurum. In cases which refuse to yield to this treatment you will consider the arguments of M. Jousset, to which I have already directed your attention (Phar- macodynamics, p. 329), and which go to prove that the Iodine injections so successful in hydrocele cure, not by setting up inflammation, but by a specific alterative influence exerted upon the serous walls of the sac. The disorders of the spermatic cord which come before us for treatment are varicocele and retraction of the testicles. Varicocele is as open to specific treatment as is varix occurring elsewhere in the body, and by the same medicines, 394 RETRACTION OF THE TESTICLES. viz. Hamamelis and Pulsatilla, whose affinity for the testicle gives them especial power over this local variety of the complaint. You may use a suspender or apply the pressure of a truss as you please : but I think you will find that the “ radical cure” of varicocele is better obtained by the use, internal and external, of these specifics than by any of the operative procedures now in vogue. Ttetraction of the Testicles must imply a spasm of the cremaster muscle. We are familiar with it as a symptom of the passage of a renal calculus : and even in apparently idiopathic cases it would be well to see if there is any obscure urinary irritation at the bottom of it. But if none such is discoverable you will do well to consider the frequent appearance of this symptom among the subjects of lead-poisoning: and Teste’s statement, that he has employed Plumbum with particular success in “ an excessively painful retraction of the testicles and penis, which seemed to re-enter the hypogastrium (in consequence of prolonged venereal excesses and repelled tetters).” When now we come to the prostate gland, you will naturally think of that chronic enlargement of its substance which is one of the troubles of old age. I cannot tell you that medicine has any control over this : nor indeed is it likely. I can only speak of the treatment of acute and chronic inflammation of the gland. 395 GONORRHOEA. Prostatitis is rarely seen save as a complication of gonorrhoea or gleet. In its acute form Pulsatilla appears to be its specific remedy, with or without Aconite as may be required. If the inflammation tend to linger in a subacute form, Dr. Yeldham recommends the administration of grain doses of Kali hydriodicum. Chronic prostatitis may be helped by Pulsatilla, but finds a still more efficient remedy in Thuja. A good case of it, treated mainly by this medicine, is recorded in the * Brit. Journ. of Horn./ vol. xxiv, p. 499. We have lastly to consider the diseases affecting the penis and scrotum, and will begin with the most common and central of all the maladies of the male sexual organs, Gonorrhoea. I have no opinion to offer as to the abortive treatment of this disease, whether by the Sepia 30 recommended by Jahr, or by the injections of the old school. But I can confidently recommend the following treatment for the fully established disorder. If your patient has it for the first time, and the inflammatory symptoms run high, put him on a low dilution of Aconite, and trust to this medicine alone. A case by Mr. Pope in vol. xxv of the ‘ British Journal/ p. 508, will show you what it can do. When the inflammatory symptoms have subsided, or if they have been moderate from the first, give Cannabis saliva steadily. It seems generally agreed 396 BALANITIS. that the proper dose for this medicine is from one to five drops of the mother-tincture. The only additional remedy likely to be required in acute gonorrhoea is Cantharis, which should be given intercurrently with the other medicines when the urinary symptoms indicate that the inflammation is extending towards the bladder. Chronic gonorrhoea—“ gleet”—is not always amenable to internal remedies, though to the Far- rum Muriaticum of the old school we have to add Cannabis, Petroselinum, Sepia, and Thuja. The last is especially serviceable when the prostate is involved, or when condylomata are present. Zin- cum Muriaticum has been found useful by Tessier. If you have to use injections, those recommended by Dr. Yeldham are effectual and uninjurious, viz. Liq. Plurnbi Diacet. 53s, Aquae Destill. $j, and an infusion of an ounce of powdered Hydrastis root to a pint of water. Dor further information upon the treatment of gonorrhoea and gleet I refer you to the last-named author’s capital book on “ Homoeopathy in Venereal Diseases,” and to some observations by Dr. V. Meyer in the Brit. Journ. of Horn., vol. xv. I have said nothing about the Copaiba and Cubebs of the ordinary treatment. There is little doubt of their action being of a specific nature: and perhaps some day they may find their place in the Homoeopathic treatment of the disease. Balanitis is not a very serious matter: but any one will SOFT CHANCRE. 397 thank you for telling them how rapidly it may be subdued by Mercurius. In neglected cases Dr. Yeldham recommends the local use of Calendula. Soft Chancre, with its suppurating bubo, is now generally recog- nised as a local affection. Mercurius is its great remedy, not on account of its relation to the syphi- litic poison, but because of its action on the part, and its power over ulcerations generally. For the same reasons Nitr’ic Acid is an excellent medicine wherewith to re-inforce the action of Mercurius when that is flagging. If the chancre should become phagedaenic, it seems generally agreed that Mercurius corrosivus is the best medicine to arrest the mischief; but I have known it cause disappointment. All these medicines are recommended in the lowest potencies. The treatment of the chancrous bubo I will borrow from the large experience of Dr. Yeldham. He recommends the early evacuation of the matter. But if this has been delayed, or the patient is un- healthy, and the bubo becomes phagedaenic, “ it demands the most careful management, both local and constitutional. The former consists, first, in the use of warm linseed poultices; and, secondly, of Calendula lotion, in the proportion of one part of the tincture to eight of water. Cotton-wool should be soaked in this, and laid in, and over, the wounds. The constitutional treatment consists in the administration of the Biniodide of Mercury, in two or three grain doses of the 2nd dec. trituration, 398 INFLAMMATION OF THE SCROTUM. if Mercury has not already been given ; or, if it have, of Acidum Nitricum, in ten drop doses of the 2nd dec. dilution; or of Kali hydriodicum, in one or two grain doses, three times a day. The patient’s powers should, at the same time, be sus- tained by a generous diet, to which a table-spoon- ful of cod-liver oil every night is an excellent addi- tion. He should, also, keep himself quiet, and as much as possible in the recumbent posture. Move- ment, from the peculiar situation of the disease, tends to retard the healing process ” (Homoeopathy in Venereal Diseases, p. 73). I must add, however, that Carlo animalis has considerable reputation in dispersing these buboes, even after fluctuation can be detected. Elephantiasis of the penis and scrotum (and pru- rigo of the latter) belongs to Cutaneous diseases; but I must speak of the form of cancer Avhich affects them, and which is nearly always Epithelioma. If this could be seen and treated early, I should expect very good results from Thuja. Later, Arsenic would probably do all that could be ex- pected from medicine. Inflammation of the Scrotum is either of the “ diffuse ” form, affecting the abun- dant cellular tissue : or one threatening mortifica- tion, analogous to the noma pudendi of the other sex. Apis for the former, Arsenicum for the latter, would be the suitable medicines. LETTER XLIII. DISEASES OE THE EE MALE SEXUAL SYSTEM. The disorders peculiar to the female sex will next engage our attention : aud from the frequency with which they come under our notice will de- mand a careful consideration. I have abundant material on which to draw,—England, .France, Spain, and America having each produced a treatise on the Homoeopathic treatment of these maladies, from the pen of Leadam, Jahr, Croserio, and Guernsey respectively. Besides these there are Dr. Peters’ Treatises on the “ Disorders of Menstru- ation ” and on the “ Diseases of Married Females.” I begin with the diseases of the ovaries. Yery little is known of the action of medicines upon these organs : but their homology with the testes leads us to apply to their morbid conditions the remedies suitable in the corresponding diseases of the latter; and we have every reason to trust the soundness of our inference. Ovaritis is very uncommon in an acute form : but when oc- curring, as from sudden suppression of the menses, Aconite and Pulsatilla are its medicines, as in the corresponding acute orchitis. When occurring in 400 OVARIAN NEURALGIA. connection with gonorrhoea, Dr. Ludlam recom- mends the internal and external use of Hamamelis. If the peritoneum be involved, Belladonna is his remedy : but I have seen this element in ovaritis rapidly dispelled by Mercurius corrosivus, while Pulsatilla was required to complete the cure. Colocynth, also, must be remembered here. Pul- satilla is often serviceable also in the more frequent chronic form of the disease : but it has a rival in Conium, which is strongly recommended by Dr. Drury. Platina is recommended by Dr. Hering in induration,* Lachesis in abscess of the ovary. Chronic ovarian trouble often comes before us as Ovarian Neuralgia. It seems probable that a large proportion of these cases depend on chronic subacute inflammation of the surface of the organ and of the adjacent peri- toneum (ovarian folliculitis and pelvi-peritonitis). We should have here, besides the occasional pa- roxysms, permanent tenderness and enlargement, and perhaps continuous pain. But there may un- questionably be a pure neurosis of the ovary, answering to the irritable and neuralgic testicle. Of the three cases cured by Dr. Burt with Hama- melis (Brit. Journ. vol. xxiii, p. 614) the first seems to belong to the former, the second and third to the latter category. This medicine is also highly praised in the inflammatory form by Dr. Ludlam, of Chicago, in his very interesting Clinical Lecture on * See a case by Mr. Harmar Smith in the ‘ Brit. Journ.’ vol. xxv, p. 157. OVARIAN DROPSY. 401 Ovaritis in the United States Medical and Surgical Journal, from which I have already quoted. Colo- cynth is also in considerable repute in ovarian neu- ralgia. Its virtues are probably owing to its specific influence upon the peritoneum,—chronic inflammation of the ovarian portion of this mem- brane so often lying at the bottom of the symp- toms. In pure ovarian neuralgia Dr. Ludlam recommends Atropine or Valerianate of Zinc. Ovarian Dropsy. In thinking over the possible curability of this disease, it must be remembered that it corresponds, not with hydrocele, but with cystic disease of the testicle. As the only help for the latter is castra- tion, so it would appear that ovariotomy is quite in place for the former. But as there is no hurry about these cases, it is worth while testing the reputed virtues of some of our medicines. Of these Apis and Iodiiim stand first: some cases illus- trating the action of the former have come from America, and there is one cured by Iodine in the Brit. Journ., vol. xx, p. 588. In Dr. Lea- dam’s book there are two cases, one of apparently complete cure, the other of great diminution of size. In the former many medicines were given, according to the general symptoms : the latter had Sepia and Sulphur. The only case I have had an opportunity of treating was a tolerably favourable one, the tumour being unilocular, and the patient’s general health excellent. I gave Apis persistently, and in various dilutions, for thj*ee months: and 402 MENORRHAGIA. then again after having tapped her, but without any result. Bromide of Potassium seems coming into use in the old school in the treatment of ovarian dropsy, and Dr. Black has just published (Brit. Journ. of Horn., Jan. 1869) a case cured by this medicine in grain doses three times a day. If ovariotomy is decided upon, our remedies for peritonitis and vomiting would probably go far to diminish the possible fatality of the operation. I will take next the disorders of menstruation, which occupy a common ground with the diseases of the ovaries and those of the uterus. I will speak first of Menorrhagia. I tliink the best division of the cases in which this trouble occurs to be that of Dr. Guernsey, who classifies Menorrhagia as Organic, Sympathetic, or Functional. Organic menorrhagia implies that some local disease of the womb is present, of which the haemorrhage—generally inter-menstrual as well as menstrual—is but a symptom. Sympathetic menor- rhagia is that which appears in Bright’s disease and in tuberculosis, in the inhabitants of malarious districts, and in the subjects of lead-poisoning. The persistent treatment of these cases must of course be that of the primary disease. But you must not therefore suppose that you cannot diminish the profuseness of the menstrual flow at the time. What Dr. Kidd has told us may be done with Sabina, Secale, and Ferrum in the menorrhagia of .MENORRHAGIA. 403 fibrous tumours (see Brit. Journ. of Horn., vol. xx, p. 52) is true also of other instances of the organic and sympathetic forms of the disease. The remedies for menorrhagia are,in the first rank, Crocus, Ipecacuanha, and Sabina; in the second, Aloes, Arsenicum, Belladonna, Chamomilla, China, Calcarea, Ferrum, Hamamelis, Platina, and Secale. I place the three first named in the front rank, because they are most frequently used. Crocus is invaluable in functional menorrhagia, when the dis- charge is blackish and lumpy. It should be given during the flow only, and China or some other medicine suited to the cause substituted in the inter- vals. I have often used it with success : but have never met with the “ sensation as if something were alive in the abdomen in the form of a ball ” which is said to be so characteristic of it. Sabina is suit- able in the frequently occurring cases which depend npon active hypersemia of the uterus: the blood is bright red. If urinary or rectal irritation co-exist, the indications for it are still clearer. It may often be continued during the intervals, as the sole remedy required. Ipecacuanha may be given where neither Crocus nor Sabina is specially indicated, and where much nausea is present. The other anti-menorrhagic medicines are called for under the following conditions. Aloes is good where the menorrhagia depends upon general pelvic congestion, and is accompanied by piles. Arsenicum, in material doses, has proved curative in some ob- stinate cases, perhaps of chronic endo-metritis. Bel- ladonna may be given when the indications are present of which I shall speak under the head of 404 MENORRHAGIA. Uterine Congestion. Chamomilla lias undoubted control over uterine haemorrhage : and may be given in preference to other medicines when it has been brought on by disturbing emotions, and where sensi- bility and mobility, local and general, are abnormally exalted. China is of course the best medicine for relieving the debility incident to menorrhagia. But it is also homoeopathic to the disorder itself, pro- ducing a flow like that of Crocus. It is accordingly specially useful to re-inforce that medicine in the menstrual intervals. It helps, moreover, to restore the periodicity in cases of irregularity. Calcarea is suitable, during the intervals, in cases where the menorrhagia is but one element of general mal-nu- trition, as in that sympathetic with tubercle. A Dr. Patzack has reported some striking cures with a medicinal course comprising Calcarea, Sulphur, China, and Nux vomica. You will find his observa- tions in Peters’ Treatise. It is doubtful to which of the medicines, or whether to all, the benefit is to be ascribed. Ferrum is good in some cases of passive menorrhagia, chiefly from organic disease of the womb. Platina is a favourite remedy for this dis- order : and would probably be most in place when it depended upon undue ovarian excitement. The same may be said of Hamamelis. With Platina the menses are too early and too long-continued, as well as profuse. Secale is given by our therapeutists as by those of the old school in atonic conditions of the uterus, as in those who have resided in tropical climates; and, strange to say, often produces its effects in infinitesimal doses. This is all I have to say about menorrhagia; and AMENORRHOEA. 405 now I have to direct your attention to the opposite condition, Amenorrhoea. I include under this heading all marked defi- ciencies of the catamenial flow, whether in quantity or quality, down to its complete absence. I will not now speak of the form of this disorder which comes before us in those entering upon puberty, a3 I shall have to speak of their troubles under the head of “ Critical Age.” But I am thinking of those in whom the menses are suddenly suppressed, or gradually diminished until they finally disappear. The treatment of these cases will vary according as the cause is local or constitutional. The menses which a chill has suddenly suppressed may often be restored then and there by the timely administration of Aconite. If too late for this, a course of Pulsatilla continued until the next period comes round rarely fails to put matters straight. But if after such suppression anjemia has set in, you will materially aid the restoration of the func- tion by a previous chalybeate course. The case I have already cited when writing upon Anaemia illustrates the advantage of this method. Cases in which the catamenia are simply sus- pended—i.e. fail to occur at the expected time— are generally due to change of climate or mode of life, and rarely cause any derangement of health or require treatment. But the most important variety of amenorrhcea is that in which the discharge, having diminished in amount for two, three, or 406 CHLOKOSIS. more periods, or the interval having become longer and longer, has finally ceased. This is generally dependent upon constitutional causes, and the men- strual suppression is but a symptom of the deranged health of the whole system. It is rare that the error is on the side of plethora. Where it is so, Belladonna should be given during the intervals, and Aconite at the periods; and the obvious hygienic regulations observed. Far more commonly the general condition is one of mal-nutrition and debility. If its character be that of ansemia simply, the chalybeate treatment already recommended is usually sufficient to set everything right. When hvdrsemia is present, and there is some pale discharge at each period, Argentum nitricum deserves attention (see the observations of Dr. Yon Grauvogl, in the Brit. Journ. vol. xxvi). The constitutional condition, however, most commonly associated with amenorrhoea is that which is styled Chlorosis. Chlorosis is, I take it, something more than anaemia : it is a cachexia. It is rare that iron alone will cure it, though with the aid of specific remedies it powerfully contributes to restore the impoverished blood. You will consider the whole group of symp- toms present; and then select a remedy corresponding bothwith these and with the depressed catamenialfunc- tion. You will generally find it amongst the following —Pulsatilla, Cyclamen, Graphites, Sepia, Sulphur, Conium, Plumbum, and Natrum Muriaticum. Pulsa- tilla is suitable for the simplest form of chlorosis, INFREQUENT MENSTRUATION. 407 where the patient is just pale, chilly, and languid, with nausea, loss of taste and appetite; the bowels regu- lar, or tending towards diarrhoea. It is much aided by Sulphur when the patient is habitually unhealthy. Cyclamen acts very like Pulsatilla : headache with dizziness and obscuration of sight are symptoms specially calling for it. Graphites stands next to Pulsatilla in the frequency of its usefulness: con- stipation and tendency to cutaneous eruptions are its special indications, and it is perhaps better when the menses are delayed, scanty, and painful, than when they are altogether absent. Sepia is most suitable when there is much leucorrhoea, and where the general dyscrasia is considerable: the rectum also gives evidence of the existence of portal or pel- vic congestion. Natrum Muriaticum also has con- stipation for one of its indications : and, like Sepia, is most useful in chronic cases with greatly impaired nutrition, as evidenced especially by the appearance of the skin. The same is to be said of Plumbum, which was introduced as a remedy for chlorosis by Dr. Winter of Lunenburg. You will find his paper translated, with some additional observations by Dr. Drysdale, in vol. i of the ‘ British Journal/ p. 160. Conium is homoeopathic where the amenor- rhcea is part of a general depression of sexual activity : in which cases the salts of Baryta also might be useful. Infrequent Menstruation requires special mention, because it may co-exist either with a scanty or with a copious discharge. 408 DYSMENORIIIICEA. In the former case the medicines—especially Gra- phites—mentioned under amenorrlioea and chlorosis have to be considered, and to these Kali carboni- cum and Dulcamara maybe added. When the flow is copious, although late, Belladonna, Calcarea, Chelidonium, China, Nux vomica, and Phosphorus are all homoeopathic, and the choice between them must be based upon the characters already assigned to these medicines. Vicarious Menstruation is rather an annoyance than a disease of moment. Dr. Leadam recommends Ferrum, and Dr. Carroll Dunham Bryonia as ordinarily the most suitable remedies for re-diverting the menstrual nisus to its proper seat. Hamamelis, also, has occasionally effected this purpose. I have last to speak of painful menstruation, Dysmenorrhoea. In undertaking tlie treatment of a case of this kind, you will of course begin by eliminating the purely mechanical variety of “ obstructive dysmenor- rhoea.'* Whether arising from congenital nar- rowness of the cervix, or from subsequent flexion of the womb, in either case it seems to require me- chanical treatment, though the latter is somewhat (as we shall see) under the influence of medicine. Functional dysmenorrhoea implies that the ova- ries and uterus (chiefly the latter) cannot perform their periodical duties without pain. Either their DYSMENORRHOEA. 409 natural livpersemia oversteps the boundary of health, or their nerves are abnormally sensitive ; or the uterine muscular fibres are prone to spasm or stiff- ened by rheumatism. The leading medicines for dysmenorrhcea will find their place under one or other of these forms. Obstructive dysmenorrhcea, i. e. when the pain is felt chiefly if not entirely before the flow begins, when not mechanical, is due to narrowing of the cervical canal by congestion or by spasm. If from congestion limited to the uterus itself, Sabina should be given during the flow and the intervals, and Aconite administered while the pain lasts. If the congestion be more general—as shown by con- stipation, liseinorrhoids, hepatic disturbance, and so on— Collinsonia is a good medicine, both at the periods and between them. Tor the spasmodic form I find Gelseminum, not higher than the 1st dec, dilution, a most excellent remedy. It is scarcely more than palliative at the time, however ; and Caulophyllum is the best medicine to be given as curative during the intervals. Its action upon the uterus is like that of Secale, but with the difference (so important here) that it influences the cervix as well as the fundus. Non-obstructive dysmenorrhcea, where the pain continues throughout the flow, means either ovarian irritation, or uterine rheumatism or neuralgia. It is probably in ovarian dysmenorrhcea that the virtues of Hamarnelis, which is attaining much reputation in this disorder, find their scope. A curious variety of this form is the “ membranous dysmenorrhcea,” in which, under the morbid ovarian stimulus, the 410 DYSMENOIUUKEA. normal catamenial exfoliation of the uterine mucous membrane becomes an inflammatory process. If the Hamamelis given for the ovaries is insufficient to cure this complication, you may with advantage remember the striking results once obtained by Dr. H. Bennet in a case of this kind from Borax (see Peters, p. 146). When the uterus is rheumatic, Actcea Racemosa is to us what Guaiacum seems to be in the old school. And when it is liable to suffer neuralgic pain in the performance of its monthly function, Chamomilla and Coffea are re- commended,—but I have seen the most speedy effects from Xanthoxylum. Dr. Hale’s experience with this drug quite coincides with this allotment of its place. “ I think Xanthoxylum,” he writes, “ more especially indicated in females of spare habit, nervous temperament, and delicate organiza- tion. In some cases of plethoric habit it has failed me.” You will observe what large use I have made of the American remedies in my recommendations for dysmenorrhoea. Indeed I should have had little to say with confidence about its treatment did I not pos- sess these valuable agents. The subject is touched with a very uncertain hand by Leadam and Peters, to whom they were unknown. LETTER XLIY. DISEASES OF THE FEMALE SEXUAL SYSTEM (icontinued). I now come to the morbid states of the uterus itself. And first of Uterine Congestion. By this name, and not by that of chronic metritis, I must describe that permanently hyperaemic con- dition of the womb which obtains when its tem- porary physiological engorgements have become pathological. There need not be any ulceration of the cervix here : and of this I shall speak sepa- rately. The medicines of chief service in this malady are Belladonna, Conium, Murex purpurea, Pulsatilla, Sabina, and Sepia. In discriminating between these, you may first divide them into two groups, according as the congestion to which they correspond is arterial or venous. In the first group we shall have Belladonna, Murex, and Sa- bina : in the second Conium, Pulsatilla, and Sepia. Then, subdividing still farther, you will think of Sabina in preference where haemorrhage is free, and there is consentaneous urinary irritation : of Belladonna where there is the characteristic sensa- tion of pressure downwards, as if the contents of 412 HYSTERALGIA. the pelvis would be forced out (Qy. tenesmus of the cervix ?) : of Murex where the patient com- plains of great faintness and sinking at the epigas- trium. In the venous cases, Pulsatilla will be most suitable when the affection is recent, and where the patient’s temperament is that belonging to this medicine ; Sepia where the rectum is in- volved in the congestion : Conium where there is evidence of diminished sexual life. You will con- sider also the character of the leucorrhoea always present in these latter cases as helping to deter- mine the choice. When long-standing congestion has brought the uterus into a state of induration, these remedies cease to be applicable, and Mercurius corrosivus and Platina take their place. There is also a form of uterine congestion not contemplated in the above remarks, viz. that se- condary to general abdominal or pelvic engorge- ment. Sulphur and Nux vomica in the former, Aloes or Collinsonia in the latter, will be the suit- able remedies. Hysteralgia. The “ irritable uterus ” is sometimes a congested one, still oftener a flexed one : and requires treat- ment accordingly. But when all such cases have been eliminated, there remain behind some to which the description of Gooch and Ferguson ap- plies,—in which the uterus, without recognisable lesion, is a constant source of trouble in itself and to the whole system. None of the old remedies CEItVICO-METllITIS. 413 are so good for this complaint as the Actcea Race- mosa. The frequent presence of a rheumatic ten- tency in the patients strengthens the indications for it. I recommend you to continue its use, in varying dilutions, for a considerable length of time. Endo-metritis. By this name I mean an inflammation (only met with as chronic) of the mucous membrane lining the body of the uterus. The membranous dysmenor- rhoea of which I have already spoken is probably of this nature: and the Borax found so useful there must not be forgotten here. But the chief remedy for endo-metritis is Arsenicum. It is especially useful when menorrhagia is a prominent symptom of the disease. I come now to the very difficult subject of the treatment of the inflammations, indurations, and ulcers of the os and cervix uteri. I will discuss the subject under the head of Cervico-metritis. There seems no reason, a priori, why ulcerations of this part should not be as curable by internal means as those which occur elsewhere. But the prejudice in favour of local caustics is so strong, and the temporary relief they afford is so obvious, that their relinquishment is one of the most diffi- cult tasks the convert to Homoeopathy has to per- form. But 1 am persuaded that he must perform it, if he wishes to be thorough in his new system, 414 CERVICO-METRITIS. and not a mere eclectic. Dr. Madden's published experience is instructive upon this point. Having devoted a good deal of attention to uterine diseases, and feeling far from satisfied with the results of internal medication in ulceration of the cervix, he proposed and for some time practised the local ap- plication of caustics (see his elaborate paper in the Brit. Journ. of Horn., voh ix, p. 11). But before many years had passed over, we find him candidly avowing that he had found the practice ultimately injurious, leading to the development of disease in other parts (see vol. xi of the same Journal, p. 638). Now he tells us (Annals, vol, v, p. 129) that he never uses any stronger application to the uterus than weak Calendula lotion. Leadam and Guernsey on the other side tell us that in- ternal medicines are sufficient without any cauteri- zation. And the current of opinion in the old school itself seems to me to be setting against the barbarous local treatment which not long ago was thought indispensable. If, however, we are to dispense with these potent measures, we must all the more carefully select our specific remedies. The main distinction I appre- hend to be between ulceration within or without the cervix. In the former case the surface affected is that of a freely-secreting glandular organ, covered with columnar epithelium : in the latter it is an ordinary mucous membrane with squamous epi- thelium, covering a fibro-muscular structure. In the former the history generally begins with leu- corrhoea, this being itself often a symptom of venous congestion j and the abnormal activity of the cervical LEUCORRHOEA. 415 muco-glands has gone on to irritation, inflammation, and ulceration. In such a case the medicines will be those for chronic leucorrhoea, of which I shall be speaking directly. The latter form of ulceration is more primarily inflammatory. If it be superficial, Mercurius solubilis or Arsenicum (the latter if the pain is burning and the patient weak) should be given internally, and injections of Calendula (one part to eight, or weaker) employed. If it be more deeply excavated, and the visible portion of the os and cervix be swollen and indurated, Mercurius corrosivus is my favourite medicine : but Dr. Leadam speaks highly of Lycopodium and Hepar sulphuris. You will of course look carefully after syphilis, and also sycosis, in your patient: and treat their local manifestations as you would do if they appeared on the penis. Leucorrhoea is indeed a symptom rather than a disease, and may be associated with many of the uterine maladies we have already considered or shall yet have to con- sider. But there are several varieties of leucorrhoea which come before us for treatment as such : and the remedies for these I shall now consider. First, we have leucorrhoea occurring in connexion with general debility—as from residence in tropical climates, over-lactation &c.—implying an atonic state of the uterus, but nothing farther. In ad- dition to the general measures you will here adopt for strengthening the system, you will remember 416 LEUCORRHCEA. the special virtues of Helonias as a uterine roborant. If, nevertheless, the leucorrhoea persists, you will find Pulsatilla the specific remedy for the morbid activity of the glands of the cervix. A still more common form of leucorrhoea is that which comes before us in those who have had severe abortions, or who have borne children too frequently. Here, I apprehend, besides debility, there is passive uterine congestion. Accordingly, Sepia is our chief remedy: and with the aid of general and local bracing will do great things for our patients. When leucorrhoea from either cause, hut especially from the latter, has lasted some time, irritation, going on to inflammation and ulceration of the glands of the cervix is set up, as has been shown by Dr. Tyler Smith. Accordingly, when Pulsatilla and Sepia have been fairly tried, but without success, or when from the symptoms or an ex- amination you diagnose disease of the cervix, you must resort to more deeply acting medicines. Of these I have most confidence in Iodine, which is especially useful in strumous or tuberculous subjects. The forms of leucorrhoea hitherto mentioned are uterine, mainly from the mucous crypts of the cervical canal. But there is a vaginal leucorrhoea, usually associated with a chronic inflammatory condition of the passage. For this Dr. Leadam strongly recommends Mercurius solubilis : hut the value of Sepia in gonorrhoea in the female—which s mainly a vaginitis—should make it serviceable also here. Thuja, moreover, has some evidence in its favour. I have only to add that in leucorrhoea from rectal P12III-UTERINE HEMATOCELE. 417 ion, besides the ever-recurring Sepia, Collin- and Aloes are indicated. ave thus endeavoured to indicate the principal ies for the principal forms of leucorrhoea. iyou meet with a case which falls under none of headings, or refuses to yield to these remedies, aust just treat it symptomatically, according 3 colour, quality, and consistence of the dis- 3, the concomitant symptoms, and so on. The ines supposed to be suitable for these will be in the Repertories. to vaginal injections in leucorrhoea, my own ence is decidedly in their favour. Free irri- i of the os and cervix daily with cold water is questionable service: and something is to be **;■ the injection of a solution of the medicine is being given internally, or of Hydrastis. se of medicinal astringents, however, I do not imend. Peri-uterine Hsematocele I its surgical rather than medical questions as s treatment. There are two occasions, how- I m which our medicines may interpose with :age. The first is when the primary hsemor- is still going on. Here Hamamelis would 3th the nature of the trouble and the source e it proceeded. The second is when the m is intra-peritoneal, and has set up inflam- i. The medicines already recommended for | aitis would now come to our aid. 418 DISPLACEMENTS OE THE UTERUS. Displacements of the Uterus, —including ante- and retroversion, and prolapsus— will next engage our attention. It may be thought that medicines can have little to say to these mechanical disorders. But remember how often the flexions of the womb depend upon congestion of the organ or the presence of fibrous tumours in its walls, and bow prolapsus generally implies weakness of the uterine supports; and the place of medicines as remedial agents is evident. What they can some- times do may be illustrated by the following case (‘ Brit. Journ. of Horn./ vol. xxiii, p. 669). “ In 1858 I was called to see an unmarried woman of thirty who had been ill for three years, and had never got much relief from any medical advice she had received. I found her general heaJth much impaired, with constant pain in the back and pelvic region, with extremely painful menstruation, her spirits depressed, and herself convinced that no one had understood her case, and feeling that there could be no cure for her. In my examination of the case I learned from her that, three years pre- viously, while assisting her father to lift some heavy article, she had felt something give way, and had become sick immediately; had kept her bed for some time after; had got little help from any medicine, and had slowly recovered so as partially to resume her labours, but had never been well since, nor ceased to suffer in the back and lower part of the abdomen. “ On making the necessary examination, I found DISPLACEMENTS OF THE UTERUS. 419 the uterus retroverted, the os pressed high up against the pubes, the fundus low down in the hollow of the sacrum. The slightest attempt to replace the organ gave such severe pain as to make me desist immediately; and, after two futile at- tempts, I decided to try Sepia 30, and see her again in a few days. I then found her feeling better, but she said that each repetition of the medicine gave pain from the inguinal region to the pubes, ‘ a kind of drawing pain/ I ordered a continuance of the Sepia, and saw her again about a week after my first examination. To my great joy I found the cervix uteri had descended an inch or more, and the fundus correspondingly ascended. I can hardly ex- press the delight felt at this discovery, believing from that moment that the idea so long cherished would be fully realized, and that my patient would be really cured when the uterus had regained its normal position, and I did not doubt that the means which had so well begun the work w'ould complete it. “ I need only add that the first menstruation after the treatment commenced was accomplished with comparatively little suffering, and that as the cure progressed the suffering ceased. The cure went steadily on, and at the third examination the position was normal : and, although the patient was obliged to rise several times each night to wrait on an aged grandmother, and did not relax from her usual duties about the house, she had no relapse. Some two years after T went to ascertain if she still remained well, and found that she had steadily gained in health, and had no return of the disease.” This case is reported by a “ lady practitioner ” 420 DISPLACEMENTS OF THE UTERUS. in America. I may also refer you to a paper by Dr. Liedbeck, of Stockholm, in vol. xx of the ‘ British Journal/ in which he relates some ex- periences with Belladonna as a uterine remedy. Two of the cases cured by it were of retroversion. He prefers using it in the form of an ointment, which is to be rubbed in to the hypogastrium and thighs. In prolapsus Stannum is a most useful medicine. It relieves speedily the sensation of bearing down, and seems to strengthen the uterine ligaments. There are also (I have mislaid the reference) some cases on record cured by Secale: and one mentioned by Biickert, of prolapsus from lifting a heavy load, in which Nux vomica and Aurum proved curative. Then Dr. Preston com- municates (c Brit. Journ./ vol. xxv, p. 497) his experience with Ferri Iodidum in uterine displace- ments in general, which seems to have been very satisfactory. Dr. Guernsey mentions a case of ten years’ standing, in which the uterus, after being once replaced, and Conium administered, came down no more. But it is no uncommon thing for such a proceeding to be followed by a cure without Conium or any other medicine,—adhesions forming between the (generally) ulcerated cervix and the vagina, which prevent the return of prolapse. You will now be able to estimate the relative place in the treatment of uterine displacements of medicines and pessaries. As a rule, you will be doing most justice to your patients if you begin with medicines alone. If, after a fair trial, mechanical support seems indispensable, do not therefoi e discon- tinue your medicines, as they may hasten the time POLYPUS UTERI. 421 when a radical cure shall have been accomplished, and pessaries be no longer needed. These remarks do not apply to the restoration of the uterus in the first instance to its normal position, as by manipula- tion or the sound. Polypus Uteri is another of those diseases in which Homoeopathy can occasionally accomplish by internal medicines that for which the knife or the ligature were thought the only remedies. Dr. Petroz considers these growths to be a manifestation of the svcotic diathesis, and gives a case in which Thvja 18 effected in eleven days the detachment of a large one, which had caused distress for a long time (Memoire sur la Sycose, in Cretin’s Edition of his collected writings). In vol. xxvi of the ‘ British Journal/ p. 364, are re- corded two cases, in one of which five fibrous polypi were expelled from the interior of the uterus under the use of Conium, and in the other one from the vagina under Thuja 1 and Calcarea 3. This action may of course have been spontaneous (see Dr. Helmuth’s paper on Fibrous Tumour in the ‘ Brit. Journ./ vol. xxiii, p. 548). The analogy of nasal polypi, in which our medicines are so often helpful, is very encouraging here. Fibrous Tumour of the Uterus you have more reason for expecting to be under the control of medicine, as Mercury, Iodine, and Bromine have already some repute in its 422 UTERINE CANCER. treatment. There is a paper on the subject by Dr. Kidd in vol. xx of the Brit. Journal. He bears testimony to the value of Mercury in discussing these tumours, recommending the bichloride (gtts.j •—iij of the 2nd dec. dilution) where profuse muco- purulent excoriating leucorrhoea exists, and the biniodide in cases characterised by a stony hardness of the tumour without much excoriation. The cases he gives, however, hardly bear out his sug- gestions, as in one of the four only was any im- pression made upon the tumour. Here, moreover, Mercurius corrosivus was the curative agent, although no leucorrhoea wras present. Dr. Helmuth, of America, who has contributed a paper on the sub- ject to vol. xxiii of the same Journal (p. 538), is less sanguine as to the results of Homoeopathic medication. The menorrhagia accompanying fibrous growths is ordinarily under the control of the usual remedies for this trouble : but you must not hesitate to give full and repeated doses of Ergot in the flooding which accompanies the expulsion of polypi. Uterine Cancer. In addition to the general remarks I have made upon the treatment of cancer, I shall now give you some reference to records of cases in which it occurred in the uterus. In vol. xvii of the ‘British Journal/ Dr. von Viettinghoff gives two cases of uterine can- cer. In one