0101 HCS 03/06/79 informatics inc information Processing Services Division 6811 Kenilworth Avenue Riverdale, Maryland 20840 301 699-7700 a cs iv INDEX ABRUPTIO PLACENTAE (See also PERINATAL MORTALITY) maternal smoking levels and, 3, 7 smokers vs. nonsmokers, 3,8 ADOLESCENTS smoking habit, 50, 52 ADVERTISING effect on cigarette consumption, 52- 53 AGING effect on mortality ratios in smokers, 28 effect on mortality ratios in ex- smokers, 36-37 AMERICAN CANCER SOCIETY STUDY methodology, 25-26 ANTISMOKING CAMPAIGNS (See also PREVENTION OF SMOK- ING) short and long term strategies, 48-50 BIRTH WEIGHT effect of carbon monoxide in rabbits, 12 effect of cessation of smoking during pregnancy, 2 effect of maternal smoking, 14 fetal and maternal carboxyhemoglo- bin levels and, 9-10 maternal smoking and, 11, 18 BLOOD VESSELS effect of carboxyhemoglobin on fetus and placenta, 9 effect of smoking, 13 BREAST FEEDING (See also LACTATION) effect of nicotine on infants, 15 BRITISH DOCTORS STUDY methodology, 26-27 CARBON MONOXIDE effect on pregnancy, 9-18 effect on birth weight and neonatal mortality in rabbits, 12 low birth weight infants and, 12 CARBOXYHEMOGLOBIN effect on fetal and placental blood vessels, 9 effect on oxygen transport in fetus, ll CARBOXYHEMOGLOBIN LEVELS birth weight and, 9-10 birth weight in rabbits and, 12 effect of maternal smoking on fe- tal/maternal ratio, 11 effect of smoking in pregnant vs. nonpregnant women, 9-10 CARDIOVASCULAR DISEASES (See also ISCHEMIC HEART DISEASE; MYOCARDIAL INFARCT; THROMBOEMBOLISM) mortality risk in oral contraceptive users and smokers, 13-14 oral contraceptives and smoking and, 18-15 CESSATION OF SMOKING (See also EX-SMOKERS; SMOKERS VS. EX-SMOKERS) effect on birth weight in offspring, 2 effect on ischemic heart disease mor- tality risk, 36 effect on lung neoplasm mortality risk, 37 effect on mortality rates and ratios, $2-37, 41-42 health benefits, 48-50 CHILDREN effect of maternal smoking during pregnancy on intellectual and physical development, &9 smoking habit, 50, 52 5T informatics inc § Information Processing Services Division 6811 Kenitworth Avenue Riverdale, Maryland 20640 301 699-7700 MEKaaee HCS 03/06/79 INDEX CIGARETTE CONSUMPTION effect of tobacco industry advertis- ing, 52-58 CIGARETTES, LESS HAZARDOUS health benefits, 48-49 mortality ratios in low vs. medium vs. high tar/nicotine smokers, 30- 81 mortality ratios in low tar/nicotine smokers vs. nonsmokers, 31 CONTRACEPTIVES, ORAL cardiovascular diseases and smoking and, 13-15 myocardial infarct and smoking and, 13-15 DDT effect of maternal smoking on levels in breast milk, 15 EX-SMOKERS (See also CESSATION OF SMOKING; SMOKERS VS. EX-SMOKERS) birth weight in offspring, 2 mortality ratios, 32-33 FETUS (See also BIRTH WEIGHT; PERINA- TAL MORTALITY) effect of carboxyhemoglobin on blood vessels, 9 effect of maternal smoking on oxy- gen transport, 11-12 HEREDITY role in disease etiology, 49 INHALATION effect on mortality ratios in ciga- rette smokers, 29 effect on mortality ratios in cigar vs. pipe smokers, 38 INTELLECTUAL DEVELOPMENT effect of maternal smoking levels during pregnancy on offspring, 8-9 ISCHEMIC HEART DISEASE (See also CARDIOVASCULAR DIS- EASES) mortality risk, effect of cessation of smoking, 36 LACTATION (See also BREAST FEEDING) effect. of maternal smoking, 15 LUNG NEOPLASMS mortality risk, effect of cessation of smoking, 37 MORTALITY annual probability of dying in smok- ers vs. nonsmokers vs. ex-smokers, 34-37 cardiovascular diseases, risk in oral contraceptive users and smokers, 18-14 cigarette vs. cigar vs. pipe smokers, 38 effect of smoking, 21-45 myocardial infarct, rates in oral con- traceptive users and smokers, 18- 14 summary of the 1964 Surgeon Gener- al’s Report findings, 22-23 summary of the 1967 Health Conse- quences of Smoking findings, 23 MORTALITY RATIOS cigarette vs. cigar vs. pipe smokers, 388, 41-48 effect of inhalation, 29,38 effect of smoking duration in cigar smokers, 39 effect of smoking duration in ciga- rette smokers, 28-29 effect of smoking duration in pipe smokers, 39-41 effect of smoking levels in cigar smokers, 39-40 effect of smoking levels in cigarette smokers, 27-29 effect of smoking levels in pipe smokers, 39-41 ex-smokers, 32-37 low tar/nicotine smokers vs. non- smokers, 31-32 low vs. medium vs. high tar/nicotine smokers, 38, 41-48 MYOCARDIAL INFARCT (See also CARDIOVASCULAR DIS- EASES) mortality rate in oral contraceptive users and smokers, 13-14 oral contraceptives and smoking and, 18-15 NATIONAL CHILD DEVELOPMENT STUDY, 8&9 NATIONAL CLEARINGHOUSE FOR SMOKING AND HEALTH effect of maternal smoking on preg: nancy, survey of public aware- ness, 16 role in prevention of smoking, 55 SUCRE cs 03/06/79 informatics inc i Informanon PTOCeSBNG SeNICes Onasion 6811 Kenitworth Avenue Riverdale, Maryland 20840 301 699-7700 cs fv, INDEX yICOTINE effect on breast-fed infants, 15 effect on mortality ratios, 30-31 \EONATAL MORTALITY effect of carbon monoxide in rabbits, 12 ONTARIO PERINATAL MORTALITY STUDY, 3 OXYGEN TRANSPORT effect of carboxyhemoglobin on fetus, 11 * effect of maternal smoking on fetus and mother, 11-12 ' ppRINATAL MORTALITY (See also ABRUPTIO PLACENTAE; BIRTH WEIGHT; PLACENTA PREVIA; PREMATURITY; STILL- BIRTHS) effect of maternal smoking, 2-3, 7 maternal smoking and, 13 risk factors, 2-3 PHYSICAL DEVELOPMENT effect of maternal smoking levels during pregnancy on offspring, 8-9 PLACENTA effect of carboxyhemoglobin on blood vessels, 9 PLACENTA PREVIA (See also PERINATAL MORTALITY) maternal smoking levels and, 3-4, 7 smokers V8. nonsmokers, 3-4, 8 PREGNANCY effect of carbon monoxide, 9-13 effect of maternal smoking, 1-13 effect of maternal smoking, public awareness, 15-16 PREMATURITY (See also FETUS; PERINATAL MOR- TALITY) maternal smoking levels and, 3-4 PREVENTION OF SMOKING (See also ANTISMOKING CAM- PAIGNS) barriers to successful control, 58-55 health benefits, 48-50 international programs, future needs, 55-56 SMOKE, CIGARETTE (See also SMOKING) synergistic action in disease etiology, 49 SMOKERS, CIGAR mortality ratios, 88-43 mortality ratios, effect of smoking duration 38-39 mortality ratios, effect of smoking levels, 38-40 SMOKERS, PIPE mortality ratios, 38-43 mortality ratios, effect of smoking duration, 38-41 mortality ratios, effect of smoking Jevels, 38-41 SMOKERS vs. EX-SMOKERS (See also CESSATION OF SMOKING; EX-SMOKERS) annual probablity of dying, 34-37 SMOKERS vs. NONSMOKERS abruptio placentae, 3, 5-6, 8 annual probability of dying, 34-37 birth weight in offspring, 4 membrane rupture during pregnancy, 18 myocardial infarct in oral contracep- tive users, 13-15 perinatal mortality, 5 placenta previa, 3-4, 6, 8 prematurity, 4 SMOKING (See also SMOKE, CIGA- RETTE; SMOKERS, CIGAR; SMOKERS, PIPE; SMOKING DU- RATION; SMOKING LEVELS; SMOKING, MATERNAL) effect on blood vessels, 183 effect on carboxyhemoglobin levels in pregnant vs. nonpregnant women, il effect on mortality, 21-45 in etiology of disease, review of mechanisms, 47-49 synergistic action in disease etiology, 49 SMOKING AND HEALTH research needs, 53-56 SMOKING DURATION (See also EX-SMOKERS, SMOKERS, CIGAR, SMOKERS, PIPE; SMOK- ING; SMOKING LEVELS) effect on mortality ratios in cigar smokers, 38-39 effect on mortality ratios in ciga- rette smokers, 28-29 effect on mortality ratios in ex- smokers, 32-34 ko akereees HCS 03/06/79 informatics inc Information Processing Services Division 6811 Kenilworth Avenue Riverdale, Maryland 20840 301 699-7700 CS iy. INDEX effect on mortality ratios in pipe smokers, 38-41 SMOKING HABIT children and adolescents, 50, 52 initiation, establishment, maintenance and modification, 50-51 research needs, 53-54, 56 trends in 20th Century, 51-53 women, 1 SMOKING LEVELS (See also SMOKERS, CIGAR; SMOK- ERS, PIPE; SMOKING; SMOKING DURATION; SMOKING LEVELS, MATERNAL) effect on mortality ratios in cigar smokers, 38-40 effect on mortality ratios in ciga- rette smokers, 27-29 effect on mortality ratios in ex- smokers, 32-34 effect on mortality ratios in pipe smokers, 38-41 effect on myocardial infarct risk in oral contraceptive users, 14-15 SMOKING LEVELS, MATERNAL (See also SMOKING, MATERNAL) abruptio placentae and, 3, 5, 7 bleeding during pregnancy and, 3, 7 effect on birth weight, 24 effect on carboxyhemoglobin levels, 10 effect on intellectual and physical development in offspring, 8-9 effect on perinatal mortality, 3, 5, 7 membrane rupture during pregnancy and, 3, 7 prematurity and, 3-4 placenta previa and, 3-4, 7 SMOKING, MATERNAL (See also SMOKING LEVELS, MATER- NAL) effect on birth weight, 1-2 effect on DDT levels in breast milk, 15 effect on fetal/maternal carboxyhem- oglobin ratio, 11 effect on intellectual and physical development in offspring, 8-9 effect on lactation, 15 effect on oxygen transport in fetus and mother, 11-12 effect on perinatal mortality, 2-3 effect on pregnancy, 1-13 effect on pregnancy, public aware- ness, 15-16 effect on umbilical artery, 13 low birth weight and, 13 perinatal] mortality and, 13 stillbirths and, 8 STILLBIRTHS (See also PERINATAL MORTALITY) maternal smoking and, 8 THROMBOEMBOLISM (See also CARDIOVASCULAR DIS- EASES) mortality rate in oral contraceptive users and smokers, 14 TOBACCO INDUSTRY effect of advertising on cigarette sales, 52-53 UMBILICAL ARTERY effect of maternal smoking, 13 U.S. VETERANS STUDY methodology, 26 WOMEN smoking habit, 1 summary of smoking related health problems, 17 Sy’vv1 8