30 janvier 1970 Dear Marshall, I understand from the paper of Gordon Sato in PNAS that you have developed a series of elegant micro-assays for the enzymes of catecholamine, acetylcholine, serotonin and GABA biosynthesis and catabolism. I have left the nematodes which do not allow me to do what I would like. I am turning now to work on mouse nervous system and mouse cell cultures. I have of course no experience in the field, but I would very much like to have in hand the techniques for the study of the transmitters. If you have no objection, I would be very grateful for a detailed protocol for these enzyme and transmitter assays. What is new with nematodes with mouse neuro-blastoma and other cells in your lab? Is there any chance to see you around Paris in the near future? With very best wishes, Yours sincerely, Francois Jacob