MAR 1? 1969 OAK RIDGE NATIONAL LABORATORY OPERATED BY UNION CARBIDE CORPORATION NUCLEAR DIVISION POST OFFICE BOX x OAK RIDGE, TENNESSEE 37830 Office of the Director March 10, 1969 Professor Joshua Lederberg Stanford University Medical Center Department of Genetics Stanford, California 94305 Dear Josh: I asked Stanley Auerbach, head of the Radiation Ecology group in our Health Physics Division, to comment on your letter of February 24. I hope that his remarks, together with the reprints, are responsive to your request. If you have further questions, I would Suggest that you or your student contact Witkamp or Auerbach directly. Sincerely ydurs, “Lee. ea AMW:p1 Alvin M. Weinberg Enclosures Thank you very much, Al. The replies are responsive (perhaps also and quite needlessly a little defensive), and I will communicate directly with witkamp. . Al, a quite different subject. Can you recall your first use of the idea of the "technological fix" in print? I ran into this myself,I belicve quite independently (but who knows?) in thinking about artificial organs and hetero-spefific transplants as a way to evade the impossible problems of organ supply from man. Taat was presented at the CIBA symp. in 1962, Sincerely, . 2 a we A Ee Pte iy + “ ~ MAR 18 1969