DEPARTMENT OF CHEMISTRY CORNELL UNIVERSITY ITHACA, NEW YORK Sept. 9, 1965 Prof. J. Lederberg, Dept. of Genetics Stanford University Dear Prof. Lederberg: Thank you tor your last letter ex, laining the notation for non—-hamiltonian circuits. No, we are not making any gauche graphs. However, my own opinion is that this "sopological hiatus" will be first filled by molecules of the type showr below. L don't see any need on my part of the complete set of graphs at this point, but I would be very interested if your proz.rams can produce the complete set of graphs on n vertices, n odd, with n-l vertices trivalent, and one vertex : divalent. Tnese would be representations of anions, cations or radicals. Sincerely,