January 7, 1946 (gery imps Joshua Lederberg Vept. of Botany Yale University New Haven, Conn. Dear Josh: Ag | mentioned to you at Boston, we should like very much to heve you spesk at a Genetics-Cytology seminar at Columbia on Tuesday, February 4, at 5 Pm (tea at 4:36). This is somewhat earlier than the date | had orignally scheduled, but | hope thet wontt inconvenience you any. (Vobzhandky says we can pay your train fere). Naturally, what we want to hear about is the recor\nation story in E. coli. | think it is only tair to say that most graduate students (for whom the seminars are designed) have only the vaguest Idea of the work, the logical structure of the arguement,nature of proofs, etc, since nothing has been published on it as yet. Therefore it seems important to me that you present the story right from the beginning. | mention this cnly because you may not realize how tew people areound here have more than rudimentary awareness of the work. Incidentally, 4 glanced brietly at the manuscript which Ryan had a couple months ago of yours. Vo you have an extra carbon copy of it lying around which you could send mebefore you come down? There are a number of points | want to get quite straight and then discuss with you, Sincepaly, Vv | Foca Note: Please send me the title of your talk for announcement purposes,