U.S. Army Chemical Corps Research and Development Command U.S. ARMY BIOLOGICAL WARFARE LABORATORIES Fort Detrick, Frederick, Maryland CHIP D-Ba+LO-FD 21 April 1960 Dr. Joshua Lederberg Genetics Department Stanford University Stanford, California Dear br. Lederberg: A little more information is available on the automatic collecting system used in the BW aerosol warning device about which I wrote to you earlier, and I am passing this along. There may be some principles here which would be applicable to remote investigation of particles in planetary atmospheres. ‘ve would be delighted to furnish all information we heve on this or other devices to any group you may have working on your problem. iy, Arthur Rawson, the engineer in this division concerned with the development of this device, asked if you are acquainted with Dr. Per Scholander of the Oceanographic Institute in La Jolla. Mr. fawson reports that Scholander has. devised some excellent equipment for micro- analysis. I appreciate the clinping you sent concerning the infra-red detecting device developed at the Army Chemical Center. “We had a parallel interest in this device and as a matter of fact had a considerably more sensitive version of it constructed for our own experimental program. we had hoped we could determine proteinaceous material in the air with it but the adsorption bands for protein in the infra-red are not too strongand the concentrations we were interested in were much lower than the concentrations needed for CW agents. I think the infra-red adsorption principle could have application in determination of planetary atmospheres and the like, but we would be a little loath to depend upon it for a determination of the presence of airborne biological matter. The NASA has cleared my talk for presentation at the SAB provided I say that they are "interested" in space vehicle sterilization rather than this is their "policy". I am sending along a copy of this paper in which you mey be interested. I felt that even befcre such a group as the SAB, one could not discuss how one might sterilize space vehicles without taking up the question of "why do it" first. 1 have borrowed quite heavily from you in this discussion and would appreciate any comments you may care to make. I hope IJ am not misquoting your thinking in this matter. CMIRD-EW~10-PD 21 April 1960 We have really done nothing cn the question of the effect of extremely high vacuum on bacteria except talk some more about it. I still think that it would be interesting tc perform the experiment some time, just as Becqueral expesed bacteria to temperatures within a fraction of a degree ef absolute zero. Dr. Urey is probably right in that we would likely find no unexpected vacuum effect, just as Becqueral found no unusual cold effect, but it would tidy up the record. JI tried to interest Ur. Krauss of the University of Maryland in the experiment, since he is already planning an experinent to see whether or not mold spores would grow in outer space, but i am afraid i: didn't get very far. His equipment is just about constructed and cannot be readily adapted to perform a vacuum experiment. Sincerely, Chale 2 Incl CHARLES R. PHILLIPS Chief, Physical Defense Division