March 26, 1962

vr. aly McKhann

Nepartment of Neurology
Massachusetts General bospital
Boston 14, Massechusetts

Dear Or, McKhann:

1 hope you wiii be giving serious consideration to the possibility
of joingag us at Stanford Medical School as Dr. Aretchmer has recently
brought up with you. { am writing myself to indicate how much | enjoyed

the prief chat we had about some problems in neurochemistry, and to
indicate how, in recent months, we have made a major decisior to Include
a vigorous effort on problems of the molecular biulogy of the nerveéeoss
system within the program of the Genetics Department. Your awn work on
the uptake of ammonia by brain protein seems to me to furnish a very
exciting lead, and the whole field should be ripe for a concerted attack
to bring problems of cerebral function into the same context as the
molecular biology of gene action and prutein syntiesis. | would personal iy
be very pleased to find you a member of our sistar depurtment, and | am
sure that this would be the occasion for @ continued and fruitful inter-
change of ideas, insights and approaches.

with cordial best wishes,

Yours sincerely,

Joshua Lederberg
Professor of Genetics

“iY py M 5 |