DEPARTMENT OF HEALTH, EDUCATION, AND WELFARE PUBLIC HEALTH SERVICE BETHESDA 14, MD. NATIONAL INSTITUTES OF HEALTH September 25, 1957 Dr. Joshua Lederberg c/o Prof. S. D. Rubbo Department of Bacteriology University of Melbourne Carlton N3, Vic., Australia Dear Joshua, Thanks for your letter of July 15. Do you have any references to the Gal 3 mutant? If you have, please send them to me as soon as possible. I am writing a review for Advances in Enzymology. In this review I had a Section on Genes and Enzymes which I first gave up because Nord wanted the manuscript right away. When I told him that I had made the article briefer and cut out a discussion on gene-enzyme interrelation, he gave me three extra weeks since he particularly welcomed a discussion of such problems in Advances in Enzymology. I will, therefore, try to formulate an additional section but it will only comprise one~half to three-quarters of a page. I shall send you a copy. I will also discuss it with Kiyoshi. Best regards to you and Esther from both of us. I am anxious to hear about your trip. I take off October 10 for Japan, India, Israel and Europe. Sincerely, Nem~ Herman M. Kalckar ae ~~ HMK: Lh National Cancer Institute National Heart Institute National Institute of Allergy and Infectious Diseases National Institute of Arthritie and Metabolic Diseases National Institute of Dental Research National Institute of Mental Health National Institute of Neurological Diseasea and Blindness The Clinical Center Division of Biological Standarde Division of Business Operations Division of Research Grants Division of Research Services