ISTITUTO SIEROTERAPICO MILANESE
“SERAFINO BELFANTI’”

ENTE MORALE AGGREGATO ALLA UNIVERSITA DI MILANO

Direttore Scientifico: Prof. Augusto De Barbieri

Via Darwin, 200 - MILANO
Diresione Scientifics TELEFONO n. 35.74.44 (5 Linee)

Wonday tne 2oth, arch

Dear Joshua, 41956

fhauks for your note of tiarch 18 . Concerning reprints:
3uu Wil be requested by the istitiuto, and 3uu by my seit, 8x a total
or obvUU;the invoice tor the total ssmould be adaressed tok the istituto.
An invoice wii be netvessary tuc toeing avie to eftect the payment.

{ fina some ditrievitzties in writing chapters lI and
V ,the material tor whicn nas beer: accumuiated and various drafts
have been already written,and shad.,i have to wait tor a period of
insplration.Are you one ot those ¢ ortunate people who can wrxks sit
down at any mouent and write whate ver necessary in good formaxam and
Styse’ I certainty am not,

AS you spoke in your dust Letter abdvuut a reaonstruction
experiment to t.st for Jacop's hyo otnesis; i made asimiitar one some
time ago but it is not quite coneliusive, Here are the essential data:
Various numbers of A ( Mr+Az*) ani/or » celis ( M-Hfr az") were cros-
sed to fle#-(1U04)celis on min, Proisotrophs were tested tor Az and F,
with the results given ;

No. celis _ Age Az®

A B he © Fe

iu! - U U 44 6 ’
= Lu? u 41 U )

4u°  4v? L 34 2 La

au! a4 3 4 37 2

tu! 4u? 5 23 ‘18 2

iu! iu? 2 16 1 7

iv? ww? 2 3 39 6

1 realise now tha’t the experiment was untair to Jacob

there being an excess or F-j;no d(osubt a great amount of infection of
Hfr x f- progecy takes place,but if the present data with an excess

of F- can be taken ag go00d,not fsriough to explain the whole of obser=
ved recombination, Mioreover,if thdimxwerextrue Jacob's hypothesis is
corpwect, there shouia be a EES ami iin Fy PHfr mutation rate of about

i in 3uU ,which seems ratner ‘in czonfLict with all the experience cumu-
tated in thousands of isoluteg firom F+ strains. It should however be
of some importance to establish -the f+ to Hfr mutation rate,and its

bearins on tne recombination fre: quencies,Have you any data,plans, sug-
gestions? Ali the best
es . —_
’ Lfa 2» Ruce -
Rostow
Polya
Steinbeck
Harris
Reid
Duvall
Riesman
Sharp
Weisinger
Gaster
Price

Whyte
Mead

Vestal
Hoyle
Mann
Childe
Goldin
Steinbeck
Swift
Metalious
Jespersen

Daily News
Mikes and Langdon

Veblen
Faulkner
Roget
Christie

Roget
Michener
Toqueville

Michener

Greene

Packard

Mikes and Bentley
Garrard

Toynbee

Mikes and Bentley
Hoyhe

Fermi

Mitford

Shipment Three

The Dynamics of Soviet Society

How to Solve It

The Wayward Bus

Recorded Gazz: A critvital Guide
Mafia

Facts of Life and Love for Teen-Agers
Individualism Reconsidered

Ancient Voyagers in the Pacific
1001 Things ¥ou Can Get Free

The Dead Sea Scriptures

Dialogues of Alfred North Whitehead

Shipment Four
The Organization Man
Cultural Patterns and Technical Change
Burl Ives Sea Songs
The old Skxanta Fe Trail
Frontiers of Astronomy
Confessions of Felix Krull
The Prehistory of European Society
The Living Talmud
The Short Reign of Pippin IV
Gulliver's Travels
Peyton Place
Growth and Structure of the English Language

Shipment Five
Handbook of Chemistry and Physics
New York City Guide and Almanac
Italy for Beginners

wie

Webster's New World Dictionary
The Theory of Business Enterprise
Intruder in the Dust
Thesaurus
Three Act Tragedy
The Burl Ives Song Book
Thesaurus
Return to Paradise
Democracy in America

“hipment Seven
Return to Paradise
The Confidential Agent
The Hidden Persuaders
How to Scrape Skies
The Worst Journey in the World
Civilization on Trial and The World and the West
How to be an Alien
The Nature of the Universe
Thermodynamics
Noblesse Oblige
Catanzaro
Weatherburn

C, Cc, Li

Winsor

Hogan

Geiringer
Pearson

Wert
Winch and McGinnis
Halsey

Shipment Eight

The Home Book of Italian Cooking
Mathematical Statistics
How to Improve your Archery
Papulation Genetics
Selected Papers on Noise and Stochastic Processes
The Space Child's Mother Goose

Shipment Nane
Dictionary of American Synonyms
The World Almanac-1958
Probability Statistics and Truth
The Grammar of Science

Shipment Ten
In search of Adam
Marriage and the Family
With Malice Toward Some

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