DEPARTMENT OF
HEALTH, EDUCATION, AND WELFARE

 

PUBLIC HEALTH SERVICE

 

IN REPLYING. ADDRESS THE

August 14, 1956

sannceeh’s © gaage “enter

tie Bact .vy Laboratories

 

tee PA

chee
Chamb we, Seorgia

Dre Je Lederberg
Department of Genetics
University of Wisconsin
Madison 6, Wisconsin

Dear Dr. Lederberg:

We have your letters of July 22 and August 11. Both Cherry
and I had examined the kunzendorf strain 302-50. In ordinary
diagnostic tests we were not able to detect crossing with group B
serum. Of course, it would be rather foolhardy to say that any
two Salmonella cultures do not have antigens in common since they all
have a tendency to degrade to rough forms which are more or less
related. I believe Cherry has written you regarding the action of
phages on the kunzendorf cultures.

Fortunately, I now have reprints from Iseki and have
returned yours under separate cover. Thank you very much indeed
for the loan of them. Some observations which Miss McWhorter made
and which Cherry followed up indicate that Iseki may be right about
V antigen. As yet we are not prepared to make any definite statements.
Of course, this affects the question as to whether antigen V was
transduced to S. abortus equi. It may be that the antigen had only
been uncovered, as the a antigen.

The H antigens of your 1043-Gz are identical with those of
S. enteritidis as demonstrated by reciprocal absorption tests. I
will send you the protocols.

For the Officer-in-Charge, Bacteriology Section
Sincerely yours,
Philip R. Edwards, Phe De

Bacteriologist-in-Charge
Enteric Bacteriology Unit