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Dear Joshua,

This is to tell you - with a few days delay,as I got the
news since more than a week but was busy with guests in the meanwhile -
that 1 have obtained a Rockefeller fellowship for a stay up to five
months in your laboratory, beginning march 15 or September.

It must be for September rather than March,and I shall not
presumably be ver to spend all the five months in the U.S.A. I hope,
however, te sping + 3 months at your place. This might be enough fir
some/Pegbard BRich we might plan in advance,and for which | would
welcome your suggestions.

As to my programme, 1 cannot fix it in detail since now,
but it would be roughly «is follows : arriving to New York ig August,
second half, spend a couple of weeks there and,if you will be at Ma-
dison in the second or third week of Sevtmmber, join you there. I shall
have to leave for italy shortly before or after Xmas,as 1 am supposed
to be back here for Jan.15 . I would like to make a two weeks trip to
Californiabmt have no idea where to fit this,as it depends on various
circumstances, like Buzzati's presence at La Jolla,and the possibility
of securing money for the journey (the Rockefeller pays only my travel
to Madison). I imagine it should be easy to make ahorter trips from
Madison to neighbouring places of scientific interest during the rest
of my stay. ,

My fellowship will paymfor self and wife, $ 325 a month.
This should be free of tazx,i imagine. I have no idea of the cost of
life at Madison,and should be grateful if you could give me a rough
impression of it. We would of course be without the children and some-
thing like a dcuble-—bedroom with use of the bathroom would suit us.

Re genetic analysis of drug resistance ; I wonder if we
might dedicate a few evenings in Madison to writing xk the booklet
you suggested ? A book of 10U-150 pages,expanding and completing the
joint paper of Rome,especially if we agreed in advance on the contents,
might be not too long to write down in detail when there,and my wife
could help in the typing etc. 1 would care for the literature in advan-
ce so as to have everything ready before I come. i would suggest to
group the contents roughly as follows :; (i)drug action - types of drugsp
their activities,mechanism of action,environment in which they act ;
(ii)drug adaptation - genetics of the individual and of the population,
experimentatl distinction, mutation to reshmbance,recombination , phy-
siology of resistance,drugs gas indueers of genetic changes ; (iii)drug

3
association (synergism and antagonism, physiol.and genetical ; (iv)drug
production — chemistry of drugs in relation to metabolites,and genetics
of antibiotic producing strains.Of course, (ii) would be the central .y

subject, out I think that an introductory (i) would be EES en BS
(F) a uppae odd Con. We werk of Come Kitp AB mene pert 4

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MILAN ESE

    
  

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