UNIVERSITY OF CALIFORNIA

DEPARTMENT OF BACTERIOLOGY April 20, 1949
BERKELEY 4, CALIFORNIA

Dr, Joshua Lederberg
Department of Genetics
University of Wisconsin
Madison, Wisconsin

Dear Josh:

Thank you for your very interesting letter, Your story about the
adaptation of lactose fermentation by growth in butyl galactoside is near-
ly incredible, I hope to be able to help you with some of these fascinating
phenomena that you are uncovering, J have received a Guggenheim Fellowship
and want to spend the first two or three months with you, My plans corres-
pond closely to your preferences in that I want to come there early in Au-
gust and stay until about October, Please let me know if this is convenient,

We are continuing the studies on the coli-mutant but have no definite
results yet, Maybe I shall have something interesting to tell you in Cin-
cinatti,

Have you seen the latest paper by Monod in which he shows the reversi-~
bility of the amylomaltase reaction? We have been scooped twice now, this
time because of the slovenly action of the J,B.C. I don't remember if I
told you that they kept the manuscript for two months until I asked about it
and then they said that they were very interested in tite paper but that the
Giscussion weakened the report, so would I shorten’the discussion, I de-
cided to hell with them and cut almost the entire discussicn out. I have
not yet received proofs,

I shall send you a culture of T, monosa as soon as I have a transfer
made,

Looking forward to seeing you in May, I am
Sincerely yours,
Michael Doudoroff
MD:hb