SUMEX

STANFORD UNIVERSITY
MEDICAL EXPERIMENTAL COMPUTER RESOURCE
RR-00785

ANNUAL REPORT—YEAR 14

Submitted to

BIOMEDICAL RESEARCH TECHNOLOGY PROGRAM
NATIONAL INSTITUTES OF HEALTH

June 1, 1987

STANFORD UNIVERSITY SCHOOL OF MEDICINE
Edward H. Shortliffe, Principal Investigator
Edward A. Feigenbaum, Co-Principal Investigator
DEPARTMENT OF HEALTH AND HUMAN SERVICES
, PUBLIC HEALTH SERVICE
NATIONAL INSTITUTES OF HEALTH

DIVISION OF RESEARCH RESOURCES
BIOMEDICAL RESEARCH TECHNOLOGY PROGRAM

ANNUAL PROGRESS REPORT
PART I., TITLE PAGE

. PHS GRANT NUMBER:

. TITLE OF GRANT:

. NAME OF RECIPIENT INSTITUTION:

. HEALTH PROFESSIONAL SCHOOL:

. REPORTING PERIOD:

Sa. FROM:
5b. TO:

. PRINCIPAL INVESTIGATOR:

6a. NAME:
6b. TITLE:

6c. SIGNATURE:

. DATE SIGNED:

. TELEPHONE:

5 P41 RROO785-14

SUMEX

Stanford University Medical
Experimental Computer Resource

Stanford University

School of Medicine

08-01-86
07-31-87

Edward H. Shortliffe, M.D., Ph.D.
Associate Professor of Medicine
and Computer Science

 

415-723-6979
5P41-RR00785-14

Table of Contents

I. Title Page
Il. Description of Program Activities

ILA. Scientific Subprojects
II.B. Books, Papers, and Abstracts
H.C. Resource Summary Table

HII. Narrative Description

Ilf.A. Summary of Research Progress
III.A.1. Resource Overview
TIE.A.1.1. SUMEX-AIM as a Resource
TH.A.1.2. The Future of SUMEX-AIM
III.A.2. Resource Definitions and Goals
IH.A.2.1. Knowledge-Based System Research
III.A.2.2. Resource Sharing
{11.A.2.3. Significance and Impact in Biomedicine
TII.A.2.4. Summary of Current Resource Goals
Ill.A.3. Details of Technical Progress
HWHIA.3.1. Progress Highlights
TH.A.3.2. Core ONCOCIN Research
HI.A.3.3. Core AI Research
[1.A.3.4. Core System Development
HIJ.A.3.5. Relevant Core Research Publications
III.A.3.6. Resource Equipment
IIE.A.3.7. Training Activities
IIL.A.3.8. Resource Operations and Usage
HLLB. Highlights
HEB.1. The MENTOR Project
III.B.2. The GUIDON Project
I1.B.3. The PROTEAN Project
Ill.B.4. The Medical Information Science Program
I1.B.5. Remote Virtual Graphics
HI.C. Administrative Changes
II.D. Resource Management and Allocation
III.D.1. Overall Management Plan
III.D.2. 2060 Cost Center
I.E. Dissemination of Resource Information
IIL.F. Suggestions and Comments

IV. Description of Scientific Subprojects
IV.A. Stanford Projects
IV.A.1. GUIDON/NEOMYCIN Project

IV.A.2. MOLGEN Project
IV.A.3. ONCOCIN Project

SAA A EoD OD DOD

E. H. Shortliffe
$P41-RR00785-14

IV.A.4. PROTEAN Project 138

IV.A.5. RADIX Project 146

IV.B. National AIM Projects 159
IV.B.1. INTERNIST-I Project 160

IV.B.2. CLIPR - Hierarchical Models of Human Cognition 165

IV.B.3. MENTOR Project 170

IV.B.4. SOLVER Project 174

IV.B.5. ATTENDING Project 181

IV.C. Pilot Stanford Projects 186
IV.C.1. REFEREE Project 187

IV.D. Pilot AIM Projects 193
IV.D.1. PATHFINDER Project 194

IV.D.2. RXDX Project 200

IV.D.3. Dynamic Systems Project 203

IV.D.4. Knowledge Engineering for Radiation Therapy 211

IV.D.5. Pathophysiologic Diagnosis Project 214
Appendix A. AIM Management Committee Membership 217
Appendix B. Scientific Subproject Abstracts 221
References 245

E. H. Shortliffe li
5P41-RR00785-14

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Figure 17:

List of Figures

A Sample OPAL Form
TALK Session Example and the Software Layers Involved in TALK
File Server Throughput Benchmarks
SUMEX-AIM DEC 2060 Configuration
SUMEX-AIM Sun File Server Configuration
SUMEX-AIM Xerox File Server Configuration
SUMEX-AIM VAX File Server Configuration
SUMEX-AIM EtherNet Configuration
Total CPU Time Consumed by Month
Monthly CPU Usage by Community
Monthly Terminal Connect Time by Community
Cumulative CPU Usage Histogram by Project and Community
Public Data Network Terminal Connect Time
INTERNET Terminal Connect Time
System Downtime -- Hours per Month
Overall System Reliability Summary
2060 Cost Center Performance

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ili E. H. Shortliffe