April 25, 1980 Dear Dr. Lederberg: This will certainly get to you after the two letters to California have gone on their way, but it may be useful in providing some new information for the other letters. I'm very encouraged by the fact that both of the callers from Pitzer and Claremont have said that I'm in the top 5 being considered for the positions. The biology job is a good deal better than the one in psychology, because it's sure of being a longer contract, and because I think that there are probably better possibilities of dialogue and collaboration with the biology faculty, but at this point I want so much not to be a postdoctoral fellow any longer that I wouldn't turn up my nose at either of them, It's not that I'm tired of research, but I am tired of being dependent on someone else. I'm also tired of engaging in hand-to-hand combat in order to get the use of the centrifuge/slice chamber/spectro- photometer/Corex test tubes... Of course, Claremont may not have any of these things, but at least that will be more peaceful, and as long as I have animal facilities and a test room, I can still do research, The decrease in research money and the increase in competition are certainly important factors in my increasing inclination to leave academia. As I said, I'm thinking about pharmaceutical houses; I've also been looking into scientific publishing. I'm enclosing my current curriculum vitae and copies of some of the teaching eyaluations from my animal behavior course. They are representative of the whole population, even though they are a limited sample; they do show what students seem to like about my teaching. I'm still plowing ahead on my biochemistry and have started a replication of my histological study; the data from the first one say that corticosterone implants shut down the adrenal cortex (no surprise) but they don't produce as much astroglial hypertrophy as we expected. I'm really getting very curious, because the two reports of hypertrophy induced by corticosterone both used a daily injection procedure. If these animals also don't respond to the corticosterone per se, it will be very interesting indeed. Thank you again for your help and advice.