JL letter to Andre Lwoff dated: 12/14/84 transcribed from manuscript _990301 relates to his reply, BBAASQ ----------------- Dear Andre: Do you by chance keep a diary? This is by way of an attempt to reconstruct the day in July 1946 when I presented E. coli K-12 to the Cold Spring Harbor Symposium. The preliminary program, enclosed, of course does not foretell the date, as the presentation was arranged ad hoc. I have no other record now but believe that Thursday (or Friday) was the likelier date. The exact date is the smallest of details. A real windfall if it existed would be your own memoir of the occasion, whether contemporary or newly written. Of course I do recall a spirited exchange of views for which I was most grateful thence forward. My regret is not to reminesce at closer hand. Perhaps an opportunity will yet arise. All best wishes, Joshua --------------------------------------------------------------------- transcribed from manuscript BBAASQ _990301 Andre Lwoff's letter to JL date: 1/3/85 Dear Joshua: Alas I have not followed the illustrious route tread by so many writers, scientists, generals, politicians etc. I do not keep I have never kept a diary. Sometimes I regret it. Of course I remember the 1946 Cold Spring Harbor Symposium (it was my first visit to the States). In fact the only important scientific event -- the most spectacular was the announcement of the sexuality of Escherichia coli. The transmission of characters from bacteria to bacteria was of course well known: the transforming principle. But that bacteria were able to copulate had to my mind never been foreseen. Somebody, maybe I, raised the objection that symbiosis between two deficient bacteria could explain your data but you masterfully eliminated this hypothesis. Anyhow the fact, bacterial sexuality, was in itself interesting for those in love with bacteria but I wonder if anyone, except you perhaps, had realized that the discovery of bacterial copulation would allow the birth and blooming of molecular biology and genetics during the next ten years -- an explosive, unpredicted blooming. This is all I can say. With kind regards. Andre Lwoff P.S. You may use this letter as you wish but please correct the mistakes concerning my English.