Clairemont Fd. . Helmont MA OSLYS C617) 494-0440, April @, i992, Me. W. Marshali Monford, OYNExXLS Assaciates, PO fox G, Manhasset, NY Liowe., Dear Mr. Monford, i share your interest in scientific terminolagy, having wntroduced the terms “auxatraph"” and "pshenome" many years aqo. And Io agree that engineering, intervention, or manipulation have undesirable avertones when applied to deliberate genetic alterations in humans. Gut “allanie” seems to me unnecessarily diverced fram the already familiar terminology of genetics, and Bt faiis ta indicate what is being changed. Might not "allogeny” and “aliaqenic”™ far the process, and "allogen” far the block af C chive and acceptabley I haven't AMA being maved, be more effe done any research on them, so [I suppose there is same danger that they have already been used in genetics. Webeter a Unabridged Internat, Dick. and ed.) lists “allogenic" as a term used in geaqlody, Hut there snould mot be any confusion in using the same term for somewhat parailel meanings in such different contexts as two fields of science. Towould take the tiberty of further ting that you may have weakened your case for replacing the undesirable present terms by your enthusiasm for an extensive new, classical terminology. i daubt that the scientific community will embrace anything iike the long list of new words that you sug@e@st, but Io can imagine that a few key authors in molecular genetics might aqree ta — promate a single key new term. Sincerely, Hernard D. Davis Adele Lehman Fraotessor of Hacterial PRysialiagy, Emeritus c/J. Lederberg mR. Hotchkiss