M. B. L. Tennis Club WOODS HOLE, MASS. June 28 Dear Josh and Esther, I'd like you to know how much I enjoyed staying with you in Madison. It was especially good to meet Novick and Bob Sachs. Our research mill is grinding steadily here, and I am getting around to looking for specific or preferential effects of presumed mutagens which would show up as restriction of the homology pattern. Sounds a little screwball, doesn't it? . After several trials I am forced to conclude that nitrogem mustard produces no lethal mutations detectable by the heterokaryon method. I have no explanation for this fantastic finding, but it is food for thought. Barbee, BJ, and Janie send their regards. hin Yours,