To: "Petros Tsipouras” <tsipouras @ikonisys.com>
Fcc: COM — =:
Subject: publication on detecting male fetal cells
Reply-to: lederberg @ mail.rockefeller.edu

 

Thu Dec 12 18:19:22 EST 2002
I just read the Development Memo, emailed today.

Petros, you have to be very careful that such a publication
is not distorted into an imputation that you are planning to
market early antenatal sex diagnosis.
===>

In Product Requirements 1.51,
I was impressed by "Results Reporting" will include "an overall
risk calculation" of a Downs fetus. That should also include
taking account of priors like maternal age, parity and previous

outcomes, and the like, as well as the implications of the test.

I hope we will have an independent "audit" of your statistical
logic. I might suggest Bert Singer at Princetion.

I assume you will also be presenting confidence limits.

Josh