THE ROCKEFELLER UNIVERSITY 1230 YORK AVENUE NEW YORK. NY 10021 dune 20, 1986 TOSHUA LEDERBERG u Dr. Barton Childs The Johns Hopkins Hospital Baltimore, Maryland 21205 PRESIDENT Dear Barton: Thank you for the introduction to the reissue of "Inborn Factors in Disease". It is a very fine analysis and I have hardly any comments. I would say that Stent grossly understates the hetero eneity of science and especially as this is divided among its disciplines. You touch upon this; but if anything that may deserve a little bit more emphasis. Geneticists were not generally expected to know. much chemistry, nor vice versa, at a time when there was little "genetic chemistry" to study -- a vicious cycle. Contrary to your page 12 it is this social organization of science rather than the technology of communication that has changed in modern times. Page 14: perhaps you would also want to add that his books were in fact reissued over some period of time during Garrod's lifetime. It would be helpful if there were a complete bibli- ography of Garrod's work on this subject including these kinds of details like new editions and so forth. Jos Lederberg Encl.