AIR MAIL December 22, 1957

Dr. G. Nossal

Hall Institute

Royal Melbourne Hospital
Parkville N2, Victoria
AUSTRALIA

Dear Dr. Nossal:

Professor Joshua Lederberg of the University of Wisconsin has re-
quested that we send you information regarding Millipore diffusion
chambers for tissue culture in vivo.

At the risk of "burying you in great reams of paper", I felt that
it might be appropriate to bring your files up to date on the

sort of thing that Millipore is doing by sending along a selection
of material having fairly broad application.

It is certainly true that Dr. Algire's work - and that by
Weaver, Prehn, Grobstein, Campbell and others - has been start-
ling in the extreme in that it has, at one stroke, established
a research procedure of new sensitivity, and also suggested the
possibilities for direct surgical intervention in humans -- in
nerve tissue regeneration problems, in surgical burn dressings
and in the transfer of endocrine tissue.

A very recent development, which - from present indications -
will surplant the use of conventional materials in this type of
work, revolves around the new MICROWEB materfals - a sample of
which I am enclosing - which provide infinitely greater mechani-
cal strength -- which is an absolute must for practical applica-
tion in human surgery. (These materials should be boiled gently
for five minutes in distilled water before use in tissue work.)

Dr, Algire has employed our convention type HA and AA materials
quite extensively. The major portion of his work has involved
17.5 mm filters (which sell for $13.70 per package of 100). He
constructs his own Lucite chamber walls - which we do not supply

   
   
 

Standard materials are available in a complete range of porosi-f
ties from 10 millimicrons to five microns - and in ultra thi
sections as well. The MICROWEB materials are available in
two porosities - WH (at 0.45 microns) and WS (at 3.0 micron#

Please do not hesitate to call on us if we may be of furthe
assistance,

Very truly yours,

’

A new standard of precision

J, ae
( Gebate’ ‘ ty in microfiltration and analysis
Walter W. Kenyon

Vice President

WWK/cap
enclosures