THE ROCKEFELLER INSTITUTE FOR MEDICAL RESEARCH

66TH STREET AND YORK AVENUE
NEW YORK @2i,N_Y.

April 1, 1959

Dr. Charles Yenofsky

Department of biological Sciences
Stanford University

Stenford, CaLifornia

Dear Charley:

We have read your and Dr. Crawford's excellent paper with
considerabie interest, and are returning it to you with a few
Suggestions and comments, many of which are indicated in pencil
on the MS, and below:

(1) In regard to the tinkage map (Fig. 1) it seems worth
considering including a few crosses between sites in the A and
B groups other than the one b-3 x A-2. the relationship is too
important to rest on one cross only.

(2) Much of the discussion (pp 13 on) seems a Little too
speculative, and adds Little to other previous discussions.

Finally, on whether this paper should be in PNAS, I am not
completely convinced that the publication therein of previous
papers in the series constitutes adequate justification. My
feeling is that in principle in such a series only the first one
opening a new field or concept, and a final definitive paper
belong here. In this regard, it would be good once in a while
to have a first-rate genetic paper of this sort in a genetics
journal.

Notwithstanding this feeling, I wilt submit this paper,
after revision, and if possible a Little condensation and tightening,
to PNAS if you so desire,

With best regards,
Sincerely,
E. L. Tat

ELT: 12