December 31, 1964
Dear Dr. Kornberg:
There have been several important developments in the field of purine-pyrimidine cocrystallization during this past year which I thought would be of special interest to you.  In particular, there is a possibility that a correlation exists between the de novo synthesis of the perfectly alternating dAT copolymer and the Hoogsteen pairing configuration found in the adenine-thymine crystalline complexes.  I have therefore taken the liberty of sending you a copy of my research proposal which describes this in considerable detail.
I would greatly appreciate your comments about this.
My best regards to you.
Sincerely yours,
Henry M. Sobell