September 26, 1977 My dear Sydney, I've been in fairly constant touch with Aaron but all I hear about you is your travels! I am enclosing, for your amusement, two short pieces I have written recently, one for the FEBS meeting in Copenhagen and the other for the Helsinki conference on chromosomes. You won't find anything new in them except for the rather cryptic sentence in italics in the middle of page 5 of the Krebs lecture report. I'd be very interested to know how you are getting on with the 'genetic engineering' work. Soon there will be so many DNA sequences that what we shall need most is good ideas on what to look for in them. Do let me know if you plan to be in the States at any time during this winter. If so, perhaps we could arrange to meet. You know you are always welcome should you wish to pay a visit here. I plan to make a real effort in the next few months to grasp the general layout of the higher nervous system of mammals but with all the other distractions this is proving very hard work. I have a whole set of naive questions, so that gives me some motivation, but it's proving very difficult to find out how to look for the answers. Next summer we hope to spend at least two months in England, staying at the cottage and visiting the lab. I may make two or three trips to the continent but hope to keep them fairly short. The exact dates of our visit are still not fixed but tentatively we plan to arrive in late May and return to La Jolla in mid-August. F. H. C. Crick