X-- * * .../"* tab r^ NATIONAL LIBRARY OF MEDICINE Bethesda, Maryland Gift of The New York Academy of Medicine THE PHYSIOLOGY OF DIGESTION CONSIDERED WITH RELATION TO THE PRINCIPLES OF DIETETICS. By ANDREW COMBE, M.D., FELLOW OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH, AND PHYSICIAN IN ORDINARY TO THEIR MAJESTIES THE KINO AND QUKEN OF THE BELGIANS. ** Nor is it left arbitrary, at the will and pleasure of every man, to do ai he list; after the dictates of a depraved humour and extravagant phoney, ti live at what rate he plea*. eth j but every one is bound to observe the Injunctions and Law of Nature, upon the pen- alty of forfeiting their health, strength, and liberty—the true and long enjoyment of them- selves." Mainwayrinsx. FOURTH AMERICAN EDITION. BOSTON: MARSH, CAPEN, & LYON. NEW-YORK: DANIEL APPLETON &. CO 1837 PREFACE. The present volume is essentially a continuation of the work first published about two years ago, un- der the title of " The Principles of Physiology ap- plied to the Preservation of Health and to the Im- provement of Physical and Mental Education ;" and its object is the same—namely, to lay before the public a plain and intelligible description of the struc- ture and uses of some of the more important organs of the human body, and to show how information of this kind may be usefully applied in practical life. In " The Principles of Physiology," the structure and functions of the skin, muscles, bones, lungs, and nervous system, the laws or conditions of their healthy action, and the unsuspected origin of many of their diseases in infringements of these laws, were explained in succession and at considerable length; and the means by which their health and efficiency might best be secured were pointed out. It was stated that, in selecting these organs as subjects for discussion, I had been guided by the desire to notice in preference those functions which are most influ- ential in their operation on the general system, and at the same time least familiarly known ; and that, if the attempt to convey the requisite information in a manner suited to the general reader should prove A 2 IV PREFACE. successful, I would afterward prepare a similar ac- count of others, in the right understanding and man- agement of which our interest is not less deeply in- volved, but in regard to which much ignorance con- tinues nevertheless to prevail, even among the most liberally educated classes of society. The numerous proofs which I received of the util- ity of my former work, not only from professional and literary journals, but also from individuals pre- viously unknown to me,—many of them guardians and instructers of youth, speaking from personal ex- perience,—together with the rapid sale of three edi- tions (the last consisting of 3000 copies) in two years, soon completely satisfied me that I had nei- ther been deceived as to the real importance of phys- iological knowledge to the general- public, nor been altogether unsuccessful in the method of conveying it. ' Thus encouraged, accordingly, I cheerfully re- sumed my labours, and began the preparation of the treatise now submitted to the indulgent consideration of the reader. The matters discussed on the present occasion relate chiefly to the function of digestion and the principles of dietetics; and in selecting them I have been guided by the same principle as before. It may, at first sight, be doubted whether I have not exceeded proper bounds in thus dedicating a whole volume to the consideration of a single subject; but the more we consider the real complication of the function of digestion,—the extensive influence which it exercises at every period of life over the whole of the bodily organization,—the degree to which its PREFACE. V morbid derangements undermine health, happiness, and social usefulness, and especially the share which they have in the production of scrofulous and con- sumptive, as well as of nervous and mental affections, —we shall become more and more convinced of the deep practical interest which attaches to a minute acquaintance with the laws by which it is regulated. In infancy, errors in diet, and derangement of the digestive organs, are admitted to be the principal causes of the striking mortality which occurs in that period of life. In youth and maturity, the same in- fluence is recognised, not only in the numerous forms of disease directly traceable to that origin, but also in the universal practice of referring every obscure or anomalous disorder to derangement of the stom- ach or bowels. Hence, too, the interest which has always been felt by the public in the perusal of books on dietetics and indigestion ; and hence the preva- lent custom of using purgatives as remedies for ev- ery disorder, very often with good, but not unfie- quently with most injurious effects. Numerous and popular, however, as writings on dietetics have been, and excellent as are many of the precepts which have been handed down by them from the earliest ages, sanctioned by the warm ap- proval of every successive generation, it is singular how very trifling their influence has been, and con- tinues to be, in altering the habits of those to whom they are addressed. In a general way, we all ac- knowledge that diet is a powerful agent in modifying the animal economy; yet, from our conduct, it might justly be inferred, that we either regarded it as totally VI PREFACE. devoid of influence, or remained in utter ignorance of its mode of operation, being left to the guidance of chance alone, or of notions picked up at random, often at variance with reason, and, it may be, in con- tradiction even with our own daily experience. The cause of this extraordinary anomaly—and it is of consequence to remark it—seems to be, not so much the absolute want of valuable information, as the faulty manner in which the subject is usually considered. In many of our best works, the rela- tion subsisting between the human body on the one hand, and the qualities of the alimentary substances on the other, as the only solid principle on which their proper adaptation to each other can be based, is altogether lost sight of; so that, while the atten- tion is carefully directed to the consideration of the abstract qualities of the different kinds of aliment, liitle or no regard is paid to the relation in which they stand to the individual constitution, as modified by age, sex, season, and circumstances, or to the observance of the fundamental laws of digestion. And hence, although these conditions are not unfre- quently of much greater importance to the general health than even the right selection of food, yet, when indigestion arises from neglecting them, the food alone is blamed, and erroneous conclusions are drawn, by relying on which upon future occasions, we may easily be led into still more serious mis- takes. It is, indeed, from being left in this way without any guiding principle to direct their experience, and test the accuracy of the precepts laid down to them PREFACE. Vll for the regulation of their conduct, that many persons begin by being bewildered by the numerous discrep- ances which they meet with between facts and doc- trine—between counsel and experience, and end by becoming entirely skeptical on the subject of all di- etetic rules whatever, and regarding them as mere theoretical effusions, based on fancy, and undeser- ving of a moment's consideration. The true remedy for this state of things is, not to turn away in disgust and despair, but to resort to a more rational mode of inquiry—-certain that, in pro- portion as we advance, some useful resujt will re- ward our labours. Such, accordingly, has been my aim in the present publication ; and if I shall be found to have been even moderately successful in attaining it, I shall rejoice in the confident conviction that others will be led to still more positive and ben- eficial results. Utility, and not novelty, has been my great object throughout; and therefore, although in some instances I have perhaps regarded known facts in a new point of view, and deduced from them prac- tical inferences of considerable value, I lay no claim to any farther originality, except such as is implied in the adoption of what I conceive to be an improved mode of investigation ; and if I have anywhere used expressions which may seem either to do injustice to others, or to arrogate too much credit to myself, it has been entirely without any such design, and, con- sequently, I will be prompt to acknowledge my error and rectify the involuntary mistake. In preparing the present volume for the press I have derived the utmost advantage from a very valu- via PREFACE. able work by Dr. Beaumont, an American writer, which, though scarcely at all known in this country, contains an authentic record of some of the most cu- rious and instructive observations which have ever been made on the process of digestion. That ex- cellent and enlightened physiologist had the rare good fortune to meet with a case where an artificial open- ing into the stomach existed, through which he could see every thing that took place during the progress of healthy digestion ; and, with the most disinterest- ed zeal and admirable perseverance, he proceeded to avail himself of the opportunity thus afforded of advancing human knowledge, by engaging the pa- tient, at a heavy expense, to live with him for sev- eral years, and become the subject of numerous and carefully conducted experiments. Of the results thus obtained, I have not scrupled to make the freest and most ample use ; both because they illustrate al- most every point of importance connected with diges- tion, and because, from Dr. Beaumont's work being still inaccessible to the British reader, it is a bare act of justice towards him, and also the best way of ful- filling the objects he had in view, to make its contents known as widely as possible : for wherever they are known they will be acknowledged to redound to his credit, not less as a man than as a philosopher. In the course of these pages the reader will occa- sionally meet with repetitions, which he may, perhaps with justice, think unnecessary. The only apology I have to offer for them is, that the intimate manner in which the different functions are connected with each other, sometimes made it impossible to explain PREFACE. IX one without referring to the rest; and also that, my prime objects being to render the meaning unequiv- ocally plain, and impress the subject deeply upon the reader's mind, I thought it better to risk occasional repetition of an important truth, than to leave it in danger of being vaguely apprehended, or its enunci- ation in any degree obscure. For these reasons, it is hoped that the fault—if such it is—will be lenient- ly overlooked. Those who wish to study more fully the subject of dietetics, will find much useful information in Dr. Hodgkin's " Lectures on the Means of Promoting and Preserving Health ;'' Professor Dunglison " On the Influence of Atmosphere and Locality, Change of Air and Climate, Seasons, Food, Clothing, Bath- ing, Exercise, Sleep, Corporeal and Intellectual Pur- suits, &c. &c. &c. on Human Health ;" Dr. Paris " On Diet;" and Dr. Kilgour's " Lectures on the Ordinary Agents of Life, is applicable to Therapeu- tics and Hygiene." Brussels, April, 1836. CONTENTS. PART I. PHYSIOLOGY OF DIGESTION. J^HAPTER I. , TRODUCTORY REMARKS. Waste or loss of substance always attendant on action.—In the vegetable and animal' kingdoms waste is greater than in the physical.—Living bodies are distinguished by possessing the power of repairing waste.—Vegetables, being rooted in one place, are always in connexion with their food.—Animals, being obliged to wanSer, receive their food at intervals into a stomach.—Nutrition most active when growth and waste are greatest.—In vegetables the same causes which increase these processes also stimulate nutrition.—But animals require a monitor to warn them when food is needed.—The sense of Ap- petite answers this purpose.—The possession of a stomach implies a sense of Appetite to regulate the supplies of food................Page 17-25 CHAPTER II. THE APPETITES OF HUNGER AND THIRST. Hunger and Thirst, what they are.—Generally referred to the stomach and throat, but perceived by the brain.—Proofs and illustrations.—Exciting causes of hunger.—Common theories unsatisfactory.—Hunger sympathetic of the state of the body as well as of the stomach.—Uses of appetite.—Relation be- tween waste and appetite.—Its practical importance.—Con- sequences of overlooking it illustrated by analogy of the whole animal kingdom.—Disease from acting in opposition to this relation.—Effect of exercise on appetite explained.— Diseased appetite.—Thirst.—Seat of Thirst.—Circumstances in which it is most felt.—Extraordinary effects of injection of water into the veins in cholera.—Uses of thirst, and rule* for gratifying it,.............26-48 12 CONTENTS. CHAPTER III. MASTICATION, INSALIVATION, AND DEGLUTITION. Mastication.—The teeth.—Teeth, being adapted to the kind of food, vary at different ages and in different animals.—Teeth classed and described.— Vitality of teeth and its advantages.— Causes of disease in teeth.—Means of protection—Insaliva- tion and its uses.—Gratification of taste in mastication.— Deglutition.............Page 48-62 CHAPTER IV. ORGANS OF DIGESTION--THE STOMACH--THE GASTRIC JUICE. Surprising power of digestion.—Variety of sources of food.— All structures, however different, formed from the same blood. —General view of digestion, chymification, chylification, san- guification, nutrition.—The stomach in polypes, in quadrupeds, and in man.—Its position, size, and complexity, in different ani- mals.—Its structure; its peritoneal, muscular, and villous coats; and uses of each.—Its nerves and bloodvessels, their nature, origins, and uses.—The former the medium of com- munication between the brain and stomach.—Their relation to undigested food.—Animals not conscious of what goes on in the stomach.—Advantages of this arrangement.—The gas- tric juice the grand agent in digestion.—Its origin and na- ture.—Singular case of gunshot wound making a permanent opening into the stomach.—Instructive experiments made by Dr. Beaumont.—Important results......63-106 CHAPTER V. THEORY AND LAWS OF DIGESTION. Different theories of Digestion.—Concoction.—Fermentation.— Putrefaction.—Trituration.—Chymical solution.—Conditions or laws of digestion.—Influence of gastric juice.—Experi- ments illustrative of its solvent power.—Its mode of action on different kinds of aliment—beef, milk, eggs, soups, &c.—In- fluence of temperature.—Heat of about 100° essential to di- gestion.—Gentle and <;ontinued agitation necessary.—Action of stomach in admitting food.—Uses of its muscular motion. —Gastric juice acts not only on the surface of the mass, but on every particle which it touches.—Digestibility of different kinds of food.—Table of results.—Animal food most digesti- CONTENTS. 13 ble.—Farinaceous next.—Vegetables and soups least digesti- ble.—Organs of digestion simple in proportion to concentra- tion of nutriment.—Digestibility depends on adaptation of food to gastric juice more than on analogy of composition.— Illustrations.—No increase of temperature during digestion.— Dr. Beaumont's summary of inferences . . Page 106-143 CHAPTER VI. CHYLIFICATION, AND THE ORGANS CONCERNED IN IT. Chylification.—Not well known.—Organs concerned in it.— The intestinal canal.—Its general structure.—Peritoneal coat.—Mesentery.—Musculai coat.—Uses of these.—Air in intestines.—Uses of.—Mucous coat.—Analogous to skin.— The seat of excretion and absorption.—Mucous glands.— Absorbent vessels.—Course of chyle tbwards the heart.— Nerves of mucous coat.—Action of bowels explained.—Indi. vidual structure of intestines.—The Duodenum—Jejunum— and Ileum.— Liver and pancreas concerned in chylifica- tion.—Their situation and uses.—Bile, its origin and uses.— The pancreas.—Its juice.—The jejunum described.—The il- eum— Coecum—Colon—and Rectum. — Peristaltic motion of bowels.—Aids to it.—Digestion of vegetables begins in stomach, but often finished in the bowels.—Illustration from the horse.—Confirmation by Dupuytren .... 144-172 PART II. THE PRINCIPLES OF DIETETICS VIEWED IN RE LATION TO THE LAWS OF DIGESTION. CHAPTER I. TIMES OF EATING. The selection of food only one element in sound digestion.— Other conditions essential.—Times of eating.—No stated hours for eating.—Five or six hours of interval between meals generally sufficient.—But must vary according to circum stances.—Habit has much influence.—Proper time for break- fast depends on constitution, health, and mode of life.—Inter- val required between breakfast and dinner—best time for dinner—circumstances in which lunch is proper—late din- 14 CONTENTS. ners considered—their propriety dependant on mode of life.-— Tea and coffee as a third meal—useful in certain circumstan- ces.—Supper considered.—General rule as to meals.—Nature admits of variety,—illustrations—but requires the observance of principle in our rules........Page 173-197 CHAPTER II. ON THE PROPER QUANTITY OF FOOD. Quantity to be proportioned to the wants of the system.—Appe- tite indicates these.—Cautions in trusting to appetite.—Gen- eral error in eating too much.—Illustrations from Beaumont, Caldwell, Head, and Abercrombie.—Mixtures of food hurtful chiefly as tempting to excess in quantity.—Examples of dis- ease from excess in servant-girls from the country, dressma- kers, &c.—Mischief from excessive feeding in infancy.—Rules for preventing this.—Remarks on the consequences of excess in grown persons.—Causes of confined bowels explained— And necessity of fulfilling the laws which God has appointed for the regulation of the animal economy inculcated 197-224 CHAPTER III. OF THE KINDS OF FOOD. What is the proper food of man ?—Food to be adapted to consti- tution and circumstances.—Diet must vary with time of life. —Diet in infancy.—The mother's milk the best.—Substi- i tutes for it.—Over-feeding a prevalent error.—Causes which vitiate the quality of the milk.—Regimen of nurses.—Wean- ing.—Diet after weaning.—Too early use of animal food hurt- ful.—Diet of children in the higher classes too exciting—and produces scrofula.—Mild food best for children.—Incessant eating very injurious.—Proper diet from childhood to puberty. —It ought to be full and nourishing, but not stimulating.— Often insufficient in boarding-schools.—Diet best adapted for different constitutions in mature age.—Regimen powerful in modifying the constitution, mental as well as physical.—Far- ther investigation required.........225-254 CHAPTER IV. CONDITIONS TO BE OBSERVED BEFORE AND AFTER EATING. General laws of organic activity apply to the stomach as well as to other parts.—Increased flow of blood towards the stomach du- CONTENTS. 15 ring digestion.—Hence less circulatingin other organs.—And consequently less aptitude for exertion in them.—Bodily rest and mental tranquillity essential to sound digestion.—Rest al- ways attended to before feeding horses.—Hence also a natural aversion to exertion immediately after eating.—Mischief done by hurrying away to business after meals.—Severe thinking hurtful at that time.—Playful cheerfulness after dinner con- ducive to digestion.—The mind often the cause of indigestion. —Its mode of operation explained—Also influences nutrition. —Illustration from Shakspeare.-^-Importance of attending to this condition of health enforced.....Page 255-268 CHAPTER V. ON DRINKS. Thirst the best guide in taking simple drinks.—Thirst in- creased by diminution of the circulating fluids.—The desire for liquids generally an indication of their propriety.—Much fluid hurtful at meals.—Most useful three orfour hours later.— The temperature of drinks is of consequence.—Curious fall of temperature in the stomach from cold water.—Ices hurt- ful after dinner.—Useful in warm weather, when digestion is completed, and caution used.—Cold water more dangerous than ice when the body is overheated.—Tepid drinks safest and most refreshing after perspiration.—Kinds of drink.—Wa- ter safe for every constitution.—Wine, spirits, and other fermented liquors, too stimulating for general use, but bene- ficial in certain circumstances.—Test of their utility 269-286 CHAPTER VI. ON THE PROPER REGULATION OF THE BOWELS. Functions of the intestines.—The action of the bowels bears a natural relation to the kind of diet.—Illustrations.—And also to the other excretions.—Practical conclusions from this.— Different causes of inactivity of bowels.—Natural aids to in- testinal action.—General neglect of them.—Great importance of regularity of bowels.—Bad health from their neglect.— Especially at the age of puberty.—Natural means preferable to purgatives.—Concluding remarks . •. . . . 287-300 Index..................301 WOOD-CUTS. Under-jaw,................49 Thoracic and Abdominal Viscera, - -...... 70 Stomach, ............---- 71 Stomachs of a ruminating animal,.....■ - - 73 Villous Coat of the Stomach,.......' - - 78 Aperture in the stomach of Alexis St. Martin, - - - 90 Abdominal Viscera,......•.....- ■ 1*7 Horizontal section of the Abdomen,.......149 Lacteals and Thoracic Duct,..........154 Thoracic Duct,.....«-......-. - I56 Contents of the Abdomen after removal of the Intestines, 161 Mucous Coat of the Duodenum, ........163 • PART I. PHYSIOLOGY OF DIGESTION. CHAPTER I. INTRODUCTORY REMARKS. Waste or loss of substance always attendant on action.—In the vegetable and animal kingdoms waste is greater than in the physical.—Living bodies are distinguished by possessing the power of repairing waste.—Vegetables, being rooted in one place, are always in connexion with their food.—Animals, being obliged to wander, receive their food at intervals into a stomach.—Nutrition most active when growth and waste are greatest.—In vegetables the same causes which increase these processes also stimulate nutrition.—But animals require a monitor to warn them when food is needed.—The sense of Ap- petite answers this purpose.—The possession of a stomach implies a sense of Appetite to regulate the supplies of food. Throughout every department of Nature waste is the invariable result of action. Even the minu- test change in the relative position of inanimate ob- jects cannot be effected without some loss of sub- stance. So well is this understood, that it is an im- portant aim in mechanics to discover the best means of reducing to the lowest possible degree the waste consequent upon motion. Entirely to prevent it is admitted to be beyond the power of man; for, how- ever nicely parts may be adjusted ,to each other, however hard and durable their materials, and how- ever smoothly motion may go on, still, in the course B2L 18 WASTE ALWAYS ATTENDANT ON ACTION. of time, loss of substance becomes evident, and re- pair and renewal become indispensable to the con- tinuance of the action. It is thus a recognised fact, or general law of na- ture, that nothing can act or move without under- going some change, however trifling in amount. Not even a breath of wind can pass along the sur- face of the earth without altering in some degree the proportions of the bodies with which it comes into contact; and not a drop of rain can fall upon a stone without carrying away some portion of its substance. The smoothest and most accurately formed wheel, running along the most level and pol- ished railroad, parts with some portion of its sub- stance at every revolution, and in process of time is worn out and requires to be replaced. The same effect is forcibly, though rather ludicrously, exem- plified in the great toe of the bronze statue of St. Peter