fev' :r.; * ,r".". IE THE MEDICAL FORMTTLARY IIEI'NG ACOLLECTION OF PRESCRIPTIONS, DERIVED FROM THE WRITINGS AND PRACTICE OF MANY OF THE MOST EMINENT PHYSICIANS IN AMERICA AND EUROPE. TO WHICH IS ADDED AN APPENDIX, CONTAINING THE USUAL DIETETIC PREPARATIONS AND ANTIDOTES FOR POISONS THE WHOLE ACCOMPANIED WITH A FEW BRIEF PHARMACEUTIC AND MEDICAL OBSERVATIONS. BY BENJAMIN ELLIS, M. D. I.4TE PROFESSOR OF MATERIA MEDICA AND PHARMACY IN THE PHILADEI.PIIU COI.I.FGE OF PHARMACY. Mnrbos autem, non eloquentia sed remediis curari."— Cels. De Med. Lib. / SIXTH EDITION, REVISED AND EXTENDED. BY SAMUEL CEORGE MORTON, M. k).. | O Y> A ". > \ P III L A DELPHI LEA & BLANCH 1842. SUAGFON GENERACSGFncr I W&-7—1801 | A: Mil) 1842; Entered according to the Act of Congress, in the year one thousand eight hundred and forty-one, by LEA & BLANCHARD, in the Clerk's Office of the District Court of the Eastern District of Penn- sylvania. GRIGGS & CO., PRINTERS. N. CHAPMAN, M. D. PROFESSOR OF THE INSTITUTES AND PRACTICE OF PHYSIC AND CLINICAL PRACTICE, IN THE UNIVERSITY OF PENNSYLVANIA, ETC. ETC. WHOSE TALENTS AND URBANITY HAVE RAISED HIM TO THE FIRST BANK IN HIS PROFESSION, AND HAVE ACQUIRED FOR HIM THE CONFIDENCE AND KSTEEM OF A LARGE AND ENLIGHTENED COMMUNITY, _ THIS WORK IS VERY RESPECTFULLY DEDICATED BY HIS OBLIGED FRIEND, THE AUTHOR. CONTENTS. Class I. Emetics - II. Cathartics Enemata III. Diuretics IV. Antilithics V. Diaphoretics VI. Expectorants Inhalation VII. Emmenagogues - VIII. Anthelmintics, IX. Epispastics Rubefacients Baths, Fomentations, §c. - Caustics, or Escharotics Mineral Acids Moxa - Stimulating Ointments, $c. - Issues and Setons Bougies X. Stimulants - XL Narcotics XII. Antispasmodics XIII. Sialagogues - XIV. Tonics Alteratives - XV. Astringents Injections • XVI. Absorbents - Appendix, No. 1. Dietetics II. Poisons III. Endcrmic Medicine, &c. - Index - THE AUTHOR'S ADVERTISEMENT TO THE THIRD EDITION. In preparing a new edition of the Medical Formu- lary for publication, we have endeavoured to render the work as complete as the nature of the subject will ad- mit. The materials have been carefully revised, and almost every class of medicines augmented, by the ad- dition of many prescriptions derived from the periodi- cal journals, standard medical works, and our pro- fessional friends. We are chiefly indebted to the writings of M. Ma- jendie, for the formulae relating to the newly discovered alkaline remedies. If we have occasionally inserted compounds which apparently belong to the pharmaco- poeia, it was from a conviction of their utility to the country practitioner, and also from the fact that they are not contained in the ordinary pharmacopoeias. The list of Poisons with their Antidotes, has been re- vised;—the Index also has been formed on a different plan from that of the first edition, and in such a way that simple medicines, and their numerous compounds, may be referred to at a glance. We cannot close this article without expressing our sincere acknowledgments to our friend Dr. Chapman, for the very flattering manner in which he has recom- mended the Medical Formulary to his class in the Uni- versity of Pennsylvania. THE EDITOR'S ADVERTISEMENT TO THE SIXTH EDITION. Having been originally associated with my lamented friend, the late Dr. Ellis, in preparing this work for the press, and having superintended two editions since his death, I now submit it to the medical public in a revised and extended form. Especial care has been taken to employ the chemical nomenclature at present in use, and to add to the former series of remedial com- binations, all those of recent discovery or modern ap- plication. This, however, I have endeavoured to ac- complish without altering the simple arrangement or unpretending character of the original work. S. G. Morton, November 1, 1841. PRE FACE. The elegant and judicious formation of prescriptions is one of the difficulties which the young practitioner in medicine is obliged to encounter. While a student, he is compelled from the circumstances under which he is placed, to confine his attention to the leading principles of the science. Consequently the minor points, (and the art of directing medicines is consi- dered one of them,) are postponed to that period when he shall have undertaken the practical duties of his profession. To obviate, in some measure, the inconvenience which the graduate at first experiences, the volume now offered to the public was undertaken and executed. It contains, in a condensed form, and we think ad- vantageously arranged, many of the most important prescriptions employed in modern practice, and which, though most of them may be already recorded, are scattered through various medical works. The arrangement framed by Professor Chapman for his Theraputics, appearing to combine greater ad- vantages than any other, we have taken the liberty of adopting as the basis of this Formulary. 2 X PREFACE. Each class has been subdivided into Powders, Pills, and Liquids; without any attempt to preserve the dif- ferent preparations of the same article together, but only with a view to convenience. A few concise rules will be found prefixed to each class, and observations have been attached to those prescriptions, which pos- sess peculiarities either in their composition or effects. The application of the remedies to diseases has been generally left to the judgment of the practitioner, and Therapeutical detail as much as possible avoided, as it would have been inconsistent with the nature and design of the work. The object is to furnish models for extemporaneous formulae, the proportions of which may be either in- Greased or diminished, according to the age, sex, con- stitution or idiosyncracy of the patient, all of which are to be taken into consideration when a proscription is directed, as well as the climate and peculiar epide- mic which may be prevailing. The prescriptions have been couched in the Latin language, and the names of the several articles will be found regularly terminated. The design was to fur- nish something like a Medical Grammar, to those un- acquainted with the dead language; and even those versed in the classics, may occasionally find words used in prescriptions which are new to them. A class of Dietetic preparations has been placed in the Appendix, No. I. They are written in the Eng- lish language, and it is hoped that they may be found PREFACE. xi useful in furnishing directions necessary to be given to the nurse. In the Appendix, No. II. we have arranged those poisons which are usually taken by accident or design, with their appropriate antidotes and some practical ob- servations. Appendix No. III. contains some concise remarks on the mode of using remedies on the *' enderrnic plan" as well as the quantities employed, and the effects pro- duced by several of the most potent remedial agents. The materials for the work have been collected from various sources, the writings of different authors, pe- riodical journals, manuscripts and the contributions of our friends. It is hoped therefore, that the dif- ficulties which have attended its progress will form some apology for the errors which it may possibly be found to contain. As a reason for not more frequently attaching the names of authors to the prescriptions, it may be observed, that they are a kind of common medical property which every physician feels himself privileged not only to employ, but modify as may best correspond with his own views. It is, therefore, dif- ficult to say to whom many of them belong; they have been touched, and retouched, till they have lost their identity. In conclusion, we beg leave to present our acknow- ledgments to some of our friends for the encouragement they have given to the undertaking. To Dr. Chap- man we are particularly indebted for the kindness and Xh PREFACE. interest he has manifested in its publication, and offer to him, (the only return we cm make,) our warmest thanks. It is with particular pleasure we embrace this opportunity of expressing our obligations to our friend Dr. S. G. Morton, whose intimate acquaintance with the subject, and classical knowledge, are only equalled by the kindness and industry he has displayed in facilitating the work. There are others whose names it would gratify us to mention, but who, we know, will be more pleased by our silence. The countenance they gave us on the present occasion has only increased the debt previously incurred. B. E. INTRODUCTION. Before entering upon the main object of this wrork, it is necessary to notice a few circumstances which pertain more especially to Pharmaceutic Chemistry, yet appear to be called for in this place; and though they are familiar to every educated physician, may be useful to the student who has not yet turned his atten- tion to prescriptions. In the first place it is requisite to be well acquainted with the signs of quantity, or those symbolic charac- ters which are used in writing prescriptions. In the ancient practice of medicine there were very many of these symbols, not only for the purpose of denoting the quantity of the ingredient, but the ingredient itself Most of these, however, have become obsolete; and a few only are retained, as indispensable to the conve- nience of the practitioner. These will be found in the following Table, which is adopted in the Pharmaco- poeias for the regulation of weights. English Name. Latin Name. Symbol. Contains A pound, An ounce, A drachm, A scruple, Libra, Uncia, Drachma, Scrupulus, lb. 3, 3, d, 12 ounces. 8 drachms. 3 scruples. 20 grains. In the manipulation of liquid substances, measures have in most countries superseded the use of weights: XIV introduction. the Table of measures recommended by the London College, gives particular names and symbols to the parts forming a gallon, in order to prevent their being confounded with those denoting weights; as in the following Table:— English Name. Latin Name. Symbol. Contains A gallon, A pint, A fluidounce, A fluidrachm, Congius, Octarius, Fluiduneia, Fluidrachma, none, 0, f 3, f 3, 8 pints. 16 fluidounces. 8 fluidrachms. 60 minims. It has been thought unnecessary in the following pages to prefix the f to the signs of quantity used for liquids, inasmuch as it is not a custom in this country to do so, nor does the omission lead to any ambiguity in compounding medicines. The minims used in the table, have been adopted by the London College in place of drops; and although we have not employed this measure in our prescrip- tions, yet we can readily perceive it possesses some important advantages over the ancient practice. The symbol (m,) is sometimes used by medical writers, though very improperly, to denote both minims and drops.* The size of a drop varies according to the greater or less fluidity and gravity of the liquid, and the shape of the vessel from which it is dropped; but as a general rule, we cannot do better on these occa- sions than use a small phial with a thin edge. Dr. Dorsey observes, that, "whenever great precision is necessary, it is easy to dilute the active medicine, and give it in form of a mixture. If sixty grains be diffused * It will be well to recollect that ten minims of any fluid, if measured by the graduated minim measure, will amount to about fifteen drops. introduction. XV in six ounces of water, for instance, each half ounce will contain five." Whenever a table-spoonful of any liquid is ordered, it is considered to be equal to half an ounce by measure; and in the same way a tea-spoonful is used for a drachm: these measures are sufficiently accurate where no great precision is requisite. All the prescriptions contained in this work, are given in the Latin language, without any other abbre- viations than those in common use to denote the quan- tity of an ingredient. The directions for the adminis- tration of medicines are expressed in English. Prescriptions, as usually sent to the Apothecaries, are much abbreviated, and the same course may be pursued with regard to those contained in this collec- tion. For the information of students who have not been in the practice of writing prescriptions, a Table of Abbreviations is subjoined. XVI INTRODUCTION. TABLE OF ABBREVIATIONS. Abbreviation. Latin Word. English Word. aa * Ana, Of each. Ad saturand. Ad saturandum, Until saturated. Ad lib. Ad libitum, At pleasure. Aq. tepid. Aqua tepida, Warm water. Aq. ferv. Aqua fervens, Hot water. Chart. Chartula, A small paper. Coch. Cochlear, A spoonful. Coch. mag. Cochlear magnum, A table-spoonful. Coch. parv. Cochlear parvum, A tea-spoonful. Colent. Colentur, Let them be strained. Collyr. Collyrium, An eye-water. Contus. Contusus, Bruised or broken. F. vel Ft. Fiat, vel Fiant, Let there be made. Fol. Folium, vel folia, A leaf or leaves. Garg. Gargarysma, A gargle. Gr. Granum, vel grana, A grain or grains. Gtt. Gutta, vel guttee, A drop or drops. Haust. Haustus, A draught. Infus. Infusio, An infusion. M. Misce, Mix. Mass. Massa, A mass. Mist. Mistura, A mixture. Pil. Pilula, vel pilnlae, A pill or pills. Pulv. Pulvis, vel pulveres, A powder or powders. Q.S. Quantum sufficit, A sufficient quantity. R- Recipe, Take. Rad. Radix, A Root. S. Signa, Write. Ss. Semi, vel dimidius, The half. Tinct. Tinctura, A tincture. The doses throughout the book are applicable to adult age, unless the contrary is specified. * This is not properly a Latin word, but the Greek proposition *ya. CLASS I. EMETICS. In the administration of Emetics, a few simple rules are worthy of attention. Whatever may be the appa- rent necessity for emptying the stomach, we must take into consideration all the circumstances of the case, and more particularly if there exist much arterial ex- citement, with determination to the head; for where these symptoms are present, blood-letting should be sometimes premised. Where poisons have been taken, our object is to evacuate the stomach as speedily as possible, and for this purpose we select an emetic which is prompt in its action. But where the excitability of the stomach is greatly diminished by a Narcotic, it is necessary to assist the emetic by the addition of some excitant. Where such an effect is caused by opium, the system may be generally rendered susceptible by the use of vinegar, mustard, or ammonia. In these cases, how- ever, the stomach-tube is our best resource. Where free vomiting is desirable, it is effectually solicited by plentiful draughts of tepid water or camo- mile tea. The evacuation of the stomach may be greatly facili- tated by tickling the fauces with a feather, or intro- ducing the point of the finger as far back as possible, and titillating the parts. There are a few cases in which emetics are obviously inadmissible, as in apoplexy, or where there is great 3 L« EMETICS. determination of blood to the head, depending upon constitutional causes; pregnancy; hernia; prolapsus uteri; active hemorrhage from the lungs and uterus, &c. If emetic medicines are ever allowable in these diseases, it is for the most part in nauseating doses only. By the frequent use of emetics, the stomach acquires an increased susceptibility to their action; hence per- sons of delicate habits should use them cautiously.— When excessive vomiting occurs, it may be checked by resort to some one or more of the following resources: Ice broken into small pieces, and allowed to dissolve in the mouth. Lime water and milk, a table-spoonful of each, mixed cold, and given at intervals of fifteen or twenty minutes. A drop, or even half a drop of oil of Creosote, mixed in a wine-glass of cold water, is one of the most effectual anti-emetic remedies. Brandy and water, and clove, and green tea, conduce to the same end; and where other internal means fail in irritable constitutions, an anodyne injection will sometimes accomplish the object. Among external appliances, mustard to the epigas- trium is one of the best: also, spice-plasters, and hot fomentations of brandy and cloves.— POWDERS. Powder of Ipecacuanha. R. Pulveris Ipecacuanhse, 3ij. Divide it into two doses.—Signa.—One to be taken in a little mo- lasses, or sugar and water, and followed by a draught of tepid water. If one powder does not produce the desired effect, the second to be taken in like manner. Powder of Ipecacuanha with Tartarized Antimony. R. Pulveris Ipecacuanhse, 9j. Tartratis Antimonii et potassae, gr. i. Misce.—To be taken in the same manner as the former. EMETICS. 19 Ipecacuanha is supposed by some to counteract the effects of opium by a specific principle, and hence the above prescription is often used where that drug has been taken: a more prompt emetic, however, will in such cases, be preferable to this. Powder of Ipecacuanha with Rhubarb. R. Pulveris Ipecacuanha?. ------ Rhei, aa. 9j. Misce, et signa.—To be taken in sirup. More or less purging will generally follow the eme- tic operation of this dose. The above are the principal combinations of ipeca- cuanha for the purpose of vomiting. It fulfils several other indications, which will be noticed under their appropriate heads. Powde%of Sulphate of Copper. R Sulphatis Cupri, gr. ij, vel x. Signa.—To be given in a little sirup of water. This medicine is seldom employed as an emetic ex- cept in those cases of poisoning where other articles have failed, or are not at hand. It should be followed by a draught of warm water. All vegetable astringent infusions are incompatible substances. Powder of Sulphate of Zinc. R. Sulphatis Zinci, gr. x, vel 5ss. Signa.—To be taken in molasses, and followed by a draught of warm water. This medicine is very prompt in its operation; and is most generally employed in cases of poisoning. It is also used as a nauseating remedy in phthisis; and both as an emetic and tonic in dyspepsia. The stomach is said to be invigorated, rather than exhausted by its operation. 20 EMETICS. WINES, MIXTURES, &c. Wine of Ipecacuanha with Antimony. R. Vini Ipecacuanha1, ^j. Tartratis Antimonii et Potassae, gr. j. Fiat Solutio.—Signa.—A tea-spoonful to be taken every ten or fifteen minutes until vomiting is induced, which may be assisted with tepid drinks. Antimonial Wine. R. Vini Antimonii, ^j. Signa.—A tea-spoonful to be taken every ten or fifteen minutes until free emesis is effected. If antimonial wine is given for the purpose of pro- ducing speedy vomiting, we may safely give half an ounce of it at once; and in the croup of infants, twenty drops every fifteen minutes, until the medicine ope- rates, is a safe dose. * Solution of Tartrate of Antimony. R. Tartratis Antimonii et Potassae, gr. vj. Sacchari albi, 3j. Aquae destillatae, ?iv. Misce.—Fiat Solutio.—A table-spoonful to be given every ten or fifteen minutes, until it operates freely. The wine of antimony possesses no advantage over this extemporaneous prescription; and unless we know the proportion of antimony contained in each ounce of the former, and know also that it has been recently made, the latter is decidedly preferable. Tartar Emetic and Quinine. R. Tartratis Antimonii et Potassae, gr. iij. Sulphatis Quiniae, gr. x. Misce et divide in partes vj. equales.—This preparation is commended by Dr. Gola as successful in intermittent fever, when quinine alone EMETICS. 21 produced no favourable result. He directs a powder to be given every two hours during the apyrexia. It causes both emesis and alvine evacuations, and prevents the recurrence of the paroxysm. Solution of Sulphate of Zinc, <$c. R. Zinci Sulphatis, 3iss. Aluminis, 3ss. Aquae ferventis, Oss. Misce.—Let the solution be filtered through blotting paper.—Signa.— A table-spoonful for adults, and a tea-spoonful for a child of six months old, (and so in proportion to the strength and age of the patient,) every morning upon an empty stomach. This is the celebrated solutio vitriolica of Dr. Mosely, who principally employed it in dysentery and phthisis pulmonalis. Mustard Draught. R. Pulveris Sinapeos, 3J- Aquae tepidae, Oss. To be mixed and swallowed at once. This is a very prompt emetic, and one that is always at hand. Emetic Lozenges of Emetina. R. Sacchari albi, ?ij. Emetinae impurae, gr. xxxij. Misce, et fiant trochisci singuli, gr. xviij. One of these Lozenges taken fasting will generally produce vomiting in children. Three or four will speedily excite it in adults. Majendie. Solution of Emetina. R. Emetinae fuscae, gr. iv. Aquae destillatae, ^ij. Syrupi simplicis, 5ss. Fiat solutio.—Signa.—Give two tea-spoonsful every half hour. Emetina is destitute of the peculiar odour and nauseous taste of Ipe- cacuanha, and may therefore be preferable in some cases. oo EMETICS. It will be observed that we have introduced the im- pure or coloured Emetina, which is much less energe- tic than the perfectly white alkali. The best antidote for an over-dose, is a strong infusion of nut-galls. One grain of Emetina will generally produce as much effect as sixteen grains of Ipecacuanha. Even this quantity of pure Emetina wTould be an unneces- sary large dose; and the emetic property will be readi- ly obtained by dissolving a grain in an ounce of water, and giving it in three or four doses at the usual in- tervals. Mixture of Ipecacuanha, fyc. R. Pulveris Ipecacuanhae, 3ss. Antimonii et potassae tartratis, gr. j. Tincturae Scillae, ^j. Aquae destillatae, 5vijss. Fiat mistura.—Signa.—Four table-spoonsful at first; afterwards two table-spoonsful every ten minutes, until vomiting is induced. This mixture is recommended in dropsies previously to giving the digitalis. Infusion of Ipecacuanha. R. Pulveris ipecacuanhae, 3ij- Aquae bullientis, 5vj. Macerate for one hour and filter.—Of this from one to two table- spoonsful, may be given every half hour, until in excite vomiting. Infusion of Lobelia Inflata. R. Herbae Lobeliae inflatae, 5j. Aquae bullientis, Oj. Fiat infusio.—Signa.—A small wine-glassful may be taken every half hour, until vomiting succeeds. This native remedy, called also Indian Tobacco, is frequently exhibited in the form of saturated tincture. The dose of the latter is a table-spoonful every half hour until emesis is excited. It has gained considera- EMETICS. 23 ble celebrity in the treatment of Asthma, and is now employed by the " Steam Doctors" of the western country, as part of their treatment of all diseases. Its activity is so great that it should be administered with caution. Sirup of Seneca and Squills. R. Syrupi Scillae compositi, 5j. Signa.—Give from ten drops to a tea-spoonful, every quarter, half, or one hour, according to the age of the patient and violence of the disease. This is the Hive Sirup of Professor Coxe: it has ac- quired much confidence from its efficacy in croup: and should it not be sufficiently active in this violent dis- ease, a grain of tartrate of antimony may be added to each ounce.—See Coxe's Bispen. p. 343. Tobacco Poultice. R. Foliorum Nicotianae, 5j. To be beat up with sufficient water to form a cataplasm.—To be applied to the region of the stomach, when emetics cannot be ad- ministered by the mouth. { -m ; CLASS II. CATHARTICS. As a general rule, it may be observed of cathartics, that they are capable of fulfilling three different indi- cations :—1st. Simply to evacuate the bowels; 2d. To excite an increased discharge from the mucous coat of the intestines; and 3d. To stimulate the neighbouring viscera, and cause them to pour out a greater quantity of their peculiar fluids. It seldom, or perhaps never, happens, that the same article will produce these three different effects; in order to do this, we must combine different substances in one formula. There are some, as magnesia, that produce their effect by absorbing the acid generated in the alimenta- ry canal, and thus become converted into a purgative salt. There are others, as aloes, that expend their principal force upon the rectum and great intestines, and for this reason are very advantageously employed in diseases of the lower bowels, as also in those of the uterus and its appendages. These remedies should always be given on an empty stomach : if administered immediately after a full meal, they arrest the digestive process, are liable to produce nausea, if not vomiting, and do not open the bowels with the same certainty or effect. When simple cos- tiveness is to be removed, the evening mav be selected for the exhibition of a cathartic. If this should not prove sufficient, we can repeat the dose in the morning and at regular intervals through the day, until the effect is produced. The principle CATHARTICS 20 says Dr. Paris, which should govern our conduct in the administration of purgatives, may be briefly stated.— The excitement is to be repeated till the requisite action is induced, yet no single excitement being such as may prove an irritant to the organ. But in the treatment of many diseases it is prefera- ble to purge through the day, in order that the sleep of the patient may not be disturbed at night. The operation of these remedies may be very much accelerated by the free exhibition of diluting drinks, such as oatmeal gruel, barley water, &c. &c. By combination we are enabled to modify and con- trol the action of many remedies, and some of the most drastic purgatives may be made to operate mildly, and yet certainly, by uniting several of them in the same dose. Finally, the operation of a cathartic may often be promoted by a judicious venesection; and if spasm of the intestines be present, opium may be advantageously joined with the purgative. POWDERS. Powder with Calomel and Jalap. R. Hydrargyri Chloridi mitis, gr. v. vel x. Pulveris Jalapae, gr. x. Misce, et signa—To be given in molasses or sirup. Powder with Calomel, Jalap and Rhubarb. R. Hydrargyri Chloridi mitis, gr. v. Pulveris Jalapae, ------ Rhei, aa, gr. v. Olei Cinnamomi, gtt. j. Misce, et signa.—To be given as the former. Powder with Magnesia and Rhubarb. R. Pulveris Rhei, 9j. Magnesiae ustae, ^ss. Olei Cinnamomi, gtt. j. Misce, et signa.—To be given in sirup, or sugar and water. 1 20 CATHARTICS. The operation of magnesia may be effectually ob- tained by giving the patient some lemonade, or a solu- tion of super-tartrate of potassa, as a common drink. Powder with Calomel and Rhubarb R. Hydrargyri Chloridi mitis, Pulveris Rhei, aa, gr. x. Olei Cinnamomi, gtt. j. Misce, et signa.—To be given in molasses. Powder with Jalap and Super-Tartrate of Potassa. R. Super-tartratis Potassae, 5ij. Pulveris Jalapce, 5j- Misce.—Divide in chartulas vj.—Of these, give one every two hours in molasses or sirup. Compound Powder ofJaktp and Gamboge. R. Super-tartratis Potassae, 5'j- Pulveris Jalapae, $). ------- Gambogiae, gr. vj. Misce.—Divide in chartulas vj.—Signa.—To be given as directed in the preceding prescription. The compound powder of jalap has been almost con- secrated to dropsical affections; but it forms a very convenient purge in many inflammatory cases; and when we wish to increase its certainty and activity, we may conveniently add the Gamboge, as in the above formula. Powder of Aloes, Canella Alba, 8,-c. R. Pulveris Aloes, 3jss. --------Canellae albae, gr. xviij. --------Radicis Serpentariae virginianae, gr. vj. Misce.—Divide in pulveres vj.—Signa.—One every three or four hours in sirup. CATHARTICS. 27 This compound, the hiera picra of the shops, forms a very good purgative, and is usually employed as an emmenagogue. Powder with Sulphate of Potassa, fyc. R. Potassae sulphatis, 5J- Pulveris Rhei, 9iss. --------Floris Anthemidis, 3j- Tere in pulverem, et divide in doses equales vj. Signa.—Take one twice a day in sugar and water. In dyspepsia and a sluggish state of the bowels. Powder of Sulphur und Super-tartrale of Potassa. R. Sulphuris sublimati, ?ss. Pulveris Super-tartratis Potassae, ^j. Misce, et signa.—Mix in a sufficient quantity of molasses, and give a tea-spoonful four or five times a day to children. In some diseases of the skin. It should be always recollected that sulphur pro- motes insensible perspiration in a very marked, degree, and hence, renders the patient more liable to be affected by the vicissitudes of climate. Powder with Milk of Sulphur and Calcined Magnesia. R. Sulphuris praecipitati vel Lactis Sulphuris, Magnesiae ustae, aa.. ?ss. Misce, et signa.—A tea-spoonful to be taken four or five times a-day. This preparation is better adapted to delicate sto- machs than the former. Either of them forms a good aperient during an alterative course of medicine. Sulphate of Magnesia and Tartrate of Antimony. R. Sulphatis Magnesiae, 3j- Tartratis Antimonii et Potassae, gr. j. Misce, et signa.—To be dissolved in six ounces of water, and taken for a dose. 28 CATHARTICS. By combining tartar emetic with this and other pur- gative salts, we promote at the same time a gentle dia- phoresis; which, in many slight inflammatory aliec- tions, is very desirable. Powder with Tartrate of Soda, Tartaric Acid, #c. vulgo, Seidlitz Powders. R. Tartratis Sodae et Potassae, 5ij. Sodae Bicarbonatis, 9ij. Fiat pulvis.—Signa.—To be dissolved in half a tumbler of cold water. R. Acici tartarici pulverizati, gr. xxv. Signa.—Dissolve in an equal quantity of water with the above, and mix them both together. To be taken while in a state of effer- vescence. This a very popular purgative, and justly so; it is a gentle aperient, and may be taken by persons whose stomachs would reject any of the ordinary saline pre- parations. Phosphate of Soda. R. Phosphatis Sodae, 5j. This salt so much resembles in taste the common table salt, (muriate of soda,) that it may be conve- niently taken in a bowl of broth. It is a mild purga- tive. PILLS. Pills of Calomel, Jalap, 8rc, {known as Griffins' Cathartic Pills.) R. Pulveris Jalapae, ------- Rhei, Saponis albi, aa. gss. Hydrargyri Chloridi mitis, gr. xxv. Tartratis Antimonii et Potassae, gr. iss. Aquae destillatae, quantum sufficit—ut fiat massa: divide in pilulas xxv. Signa.—Two of these pills may be taken at once, and repeated in two hours, if not sufficient. CATHARTICS. 29 This combination of purgatives with the tartrate of antimony, forms a most excellent anti-bilious remedy; and, in cases of fever, prepares the alimentary canal for the reception of other remedies better than a more simplified preparation. Pills of Blue Mass, Aloes, fyc. R. Massae ex Hydrargyro, Pulveris Jalapae, -------Aloes, aa. gr. xv. Syrupi simplicis, q. s. ut fiat massa, et divide in pilulas xij. Signa.—Three may be taken at night, and the same dose repeated in the morning, if the first is ineffectual. Pills of Blue Mass, Soda, $c. R. Massae ex Hydrargyro, gr. ix. Pulveris Rhei, Bicarbonatis Sodae, aa. gr. xij. Syrupi Rhei aromatici, q. s. ut fiat massa, et divide in pilulas, xij. Signa.—One, twice or three times a-day, as an alterative in derange- ment of the liver. Hartshorne. Powdered Charcoal. R. Pulveris Carbonis, 3j. Of this a tea-spoonful may be given in milk, molasses, or sugar and water; repeated as often as necessary to keep the bowels in a solu- ble state. Charcoal occasionally accumulates in the bowels, and occasions the most distressing constipation. When it fails, therefore, to operate promptly, some other pur- gative should be given. It may be observed, that charcoal is exceedingly well adapted to many cases of dyspepsia, enabling the patient to digest more, and a greater variety of food, than he can without it. The safest and most effectual mode of using it is to dust it over the aliments in the same way as pepper. 30 CATHARTICS. Pills of Calomel, Rhubarb, and Opium* R. Hydrargyri Chloridi mitis, gr. xij. Pulveris Rhei, gr. xx. --------Opii, gr. j. Misce, et divide in pilulas viij.—Signa.—Four may be taken at once, and the remainder in one hour if the first are insufficient. This compound may be employed when we wish the effect of calomel, and when there is pain in the bowels; if there should be much costiveness, it may be necessary to follow the pills with a dose of castor oil, or Epsom salts. Pills of Rhubarb and Soap. R. Pulveris Rhei, 5j. Saponis albi, gr. x. Aquae destillatae, q. s.—ut fiant pilulae xv. Signa.—Three for a dose. To remove costiveness, or produce a gentle evacua- tion in debilitated habits. Pills of Aloes and Rhubarb. R. Pulveris Rhei, --------Aloes aa. 2ss. Saponis albi, quantum sufficit—ut fiant pilulae xxv. Signa.—Three or four of these may be taken occasionally, in habitual costiveness and in dyspepsia. Pills of Rhubarb, with Sulphate of Iron, &c. R. Pulveris Rhei, riss. Sulphatis Ferri, ?ss. Saponis albi, 9ij. Aquae destillatae, q. s.—Fiat massa in pilulus xl. dividenda. The intention of these pills is obviously to remove costiveness, and impart tone to the bowels. They were a favourite medicine with Dr. Griffitts, late of CATHARTICS. 31 tli is city. Three or four may be taken for a dose at bed-time. Pills with Aloes, Gentian, fyc. R. Pulveris Aloes, 2j. Extracti Gentianae, rss. Olei Carui, gtt. x. Syrupi simplicis, quantum sufficit. The mass to be divided into pills, each one weighing gr. iv.—Sig- na.—Two or three for a dose. Pills of Croton Oil. R. Olei Tiglii, gtt. j. Micae panis, q. s.—ut fiant pilulae iv. Signa.—One every hour until they operate. This powerful remedy has lately been restored to the materia medica. One drop is a full dose, and fre- quently less will answer every purpose. Pill with Aloes, Ipecacuanha, fyc. R. Pulveris Aloes, Jss. --------Ipecacuanhae, gr. iv. Saponis albi, 9ij. Syrupi simplicis, q. s.—ut fiant pilulae xx. Signa.—Two or three for a dose; and to be repeated when necessary. These pills, with almost any other of the aloetic pre- parations, from their specific action on the rectum, will sometimes restore suppressed haemorrhoids. Aperient Pills. R. Aloes socotorinae, gj. Pulveris Rhei, ^j. -------Ipecacuanhae, gr. vj. Saponis venetae 9j. To be divided into sixty-four pills.—As a simple aperient, one may be taken every night at bed-time; but where a full purgative effect is desirable, the dose is two or three. 32 CATHARTICS. Pills with Asafcelida and Aloes. R. Gummi Asafcetidae, Pulveris Aloes, Saponis albi, 5a. 5SS- Aquae destillatae, quantum sufficit—ut fiat massa in pilulas xxv. di- videnda. These pills are usually kept made by the apotheca- ries, but the physician may prefer them recent, and therefore the formula is here inserted. We may alter this prescription by substituting rhubarb for aloes, if it is deemed preferable. Three or four of them are suf- ficient for a dose. Pills with Extract of Butternut, Jalap, fyc. R. Extracti Juglandis cinerei, 5SS« Pulveris Jalapae, 9j. Saponis albi, gr. x. Misce.—Fiant pilulae xv. Signa.—Three or four of these may be taken for a dose, and if they do not operate, two or more may be safely administered. The extract of Butternut, either alone or in combi- nation, is very highly recommended as a cathartic in fevers, dysentery, &c. Pills of Blue Mass, and Colocynth. R. Massae ex Hydrargyro Extracti colocynthidis, 5a. gr. v. Olei Carui, gtt. ij. Fiant pilulae, ij. These constitute an active cathartic. Confection of Sulphur. R. Sulphuris sublimati et loti, 5iss. Confectiones Sennae, 5ij. Potassae nitratis, giij. Syrupi Aurantii, q. s.—ut fiat confectio. CATHARTICS. 33 Signa.—From one or two drachms may be taken once or twice a-day. Useful in haemorrhoidal affections. Pills of Compound Extract of Colocynth and Calomel. R. Extracti Colocynthidis compositi, gr. xlviij. Hydrargyri chloridi mitis, gr. xij. Misce et divide in pilulas xij. Signa.—One, or at most two of these pills will generally act as a cathartic. Pills of Compound Extract of Colocynth, <$c. R. Extracti Colocynthidis compositi, Bj. ------ Jalapae resinosi, gr. vj. Pulveris Scammoniae compositi, gr. x. Hydrargyri chloridi mitis, gr. x. Tartratis Antimonii et Potassae, gr. j. Saponis veneti, gr. v. Olei Cassiae, gtt. iv. Misce et divide in pilulas xv. Signa.—One, two, or three to be taken at bed-time, for a cathartic. Dr. Meigs. Pills with Aloes and Mercurial Blue Mass. R. Massae ex Hydrargyro, 9j. Pulveris Aloes, gr. xxv. Misce et divide in pilulas xv.—Signa.—One every two hours until they operate. In cases of constipation depending upon deficiency of bile, these pills may be advantageously employed. Pills of Compound Extract of Colocynth, %c. 8,-c, commonly called FothergiWs Pills. R. Extracti Colocynthidis compositi, 5iss- * Oxidi Antimonii illoti, 5SS» Misce et divide in pilulas xxx.—One of these pills will frequently produce a free evacuation; but two or more may be taken when required, at bed-time. * This preparation of antimony was formerly known by the name of Calx Antimonii Illota. 5 3-1 CATHARTICS. Pills with Aloes, (iuaiacum, $c. R. Pulveris Guaiaci, 5ss. ------- Aloes, gr. xxxvj. ------- Rhei, j~ij. Balsami Canadensis, quantum sufficit—ut fiat massa in pilulas xlviij. dividenda. Signa.—One to be taken every three hours. This combination forms a highly stimulating ca- thartic. Electuary of Senna and Figs. R. Pulveris Sennae, 3ss. Pulpae ficus, quantum sufficit—ut fiat electuarium. Signa.—A piece, the size of a marble, night and morning, in costive- ness from sedentary habits. MIXTURES, INFUSIONS, &c. Oleaginous Mixture. R. Olei Ricini, 3iss. Pulveris gummi Arabici, 5M- Sacchari albi, 3j- Misce secundum artem, et tunc adde gradatim— Aquae Menthae sativae, 3iv. Tincturae Opii, gtt. xl vel 1. Signa.—A table-spoonful every hour and a half or two hours, until it purges. It is of some consequence in preparing this mixture, to shake the oil and powders well together before add- ing the water, which should be poured in grad ually, agitating it after each addition; or, combine the whole in a mortar. Mixture of Oil of Turpentine, fyc. R. Olei Terebinthinse rectificati, 5j. Pulveris Gummi Arabici, ------- Sacchari albi, 55. 3ij. Aquae Mentha? sativae, 5iv. Misce, et Signa.—A table-spoonful every two hours, until it operates. CATHARTICS. 35 This preparation must be made in the same manner as the oleaginous mixture. Mixture with Magnesia, Tinct. Foclida, »$-c. R. Magnesiae carebonatis, 5ss. Tincturae Asafoetidae, gtt. lx. ------- Opii. gtt. xx. Sacchari albi, 3j- Aquae destillatae, 5j. Misce.—Fiat mistura.—Signa.—Twenty-five drops may be given to an infant of two or four weeks old; in flatulent cholic, diarrhoea, &c. This preparation is strongly recommended and much employed by Dr. Dewees of this city. If the calcined magnesia be used, it unites with the resin of the asafoetida, forms an almost solid mass at the bottom of the vessel, and defeats the object of the prescription. Mixture of Carb. Magnesia, fyc. R. Magnesiae carbonatis, 3ss. ------- Sulphatis, 3iij- Spiritus Ammonia? aromatici, 3j« Tincturae Rhei, 5ss. ------- Hyosciami, Jss. Aquae Menthae sativae, ?iv. Fiat mistura.—Signa.—A large table-spoonful to be taken two or three times a-day. Dr. Meigs. Oleaginous Mixture with Oil of Turpentine. R. Olei Ricini, 5iss. Vitellum ovi, j. Sacchari albi, 3ij- Olei Terebinthinae rectificati, 5ss. Aquae Menthae sativae, ?iv. Misce optime et fiat mistura.—Signa.—A large table-spoonful may be taken every hour, according to circumstances. This preparation is much used by some of our best practitioners, in cases requiring a brisk and stimulating 36 CATHARTICS. cathartic. It has also been recommended as a purga- tive, after the effects of an over-dose of opium have been partially subdued by the proper preliminary remedies. Mixture of Oil of Euphorbia Latyris, or Oil of Spurge. R. Olei Euphorbia? latyris, gtt. viij. Gummi Acacia?, Sacchari albi, aa. 5j> Aquae Menthae sativae, ^j. Fiat mistura.—Signa.—One half of this mixture may be given at once, and repeated in two hours if the bowels are not moved. The oil of spurge is an old remedy, lately revived and introduced to notice by the Italians. The Euro- pean oil is stated to be as mild as castor oil, and as prompt and efficacious as the croton oil, in the above doses. The oil prepared from the beans grown in this country, is said to be much more acrid, occasioning both nausea and griping. Mixture of Croton Oil. R. Olei Tiglii, gtt. j. Mucilaginis acacia?, Aquae destillatae, 55. 5j. Misce et Signa.—To take a tea-spoonful every two hours until it operates. Saponaceous Solution of Croton Oil. R. Olei Tiglii, gtt. viij. Potassae purae, gr. vj. Aquae destillatae, 3ij. Fiat solutio.—Signa.—From three to six drops may be given for a dose. This is a substitute for the soap of the croton oil proposed by the French, and which is more trouble- some to make. Mr. Conevel states, that four drops of this oil rubbed on and round the umbilicus, will produce a cathartic CATHARTICS. 37 effect; even the odour of it has been known to excite the alimentary canal, either as an emetic or purgative. Solution of Epsom Salts with Nitric Acid. R. Sulphatis Magnesia?, 5ss. Tincturae Jalapae, 3j- Acidi nitrici, gtt. x. Aquae Menthae, 5ij. Misce.—Signa.—To be taken for a draught. The nitric acid is said to destroy in great measure the bitter taste of the salt. Infusion and Tincture of Senna, S,-c. R. Infusionis Senna?, 3vj« Tincturae-------, 3ij. Mannae, 3ij. Magnesiae sulphatis, 5ss. Aqua? Menthae sativa?, ---- destillatae, 55. 5iss. Misce.—Signa.—One half to be taken for a dose, and repeated if it does not operate. This was a very common prescription of the late Mr. Abernethy, of London. Purgative Draught. R. Foliorum Senna?, Jij- Sulphatis soda?, 5ss. Aquae, ^iv. Syrupi Rhamni, 5j. The water should be added boiling hot, and the infusion then cooled and strained. A few grains of Jalap may be substituted for the Sirup of Buckthorn. Mixture of Magnesia, Rhubarb, iyc. R. Magnesia? ustae, 3ss. Pulveris Rhei, gr. vj. ------- Sacchari albi, 3j> Essentia? Menthae piperita?, gtt. vj. Aquae destillatae. Siss. Fiat mistura.—Signa.—A tea-spoonful to be given every two hours to children, until it operates. 38 CATHARTICS. This preparation is designed for the bowel com- plaints of children, in which it is very serviceable. Laudanum can be added according to the age and circumstances of the patient. Solution of Sulphate of Magnesia, Misce, et signa.—To be infused in a pint of boiling water for half an hour; one-half to be taken at once; if insufficient, the remainder in two or three hours. This infusion may be longer kept if a little tinctura sennse be added to it. Decoction of Prunes. R. Fructus Pruni, 5iij. Aquae, Jfeiij. Decoque ad libras duas.—Used as a mild laxative. Infusion of Senna with Rhubarb, Sfc. R. Foliorum Senna?, 5vj. Manna? optima?, 5j. Radicis Rhei contusae, 3ij. Seminum Cardamomi contus: 3ij. CATHARTICS. 39 Misce, et signa.—To be infused in a pint of boiling water for one hour. A tea-cupful given every hour till it operates. Compound Tincture of Senna, vulgo, Warner's Cordial. R. Tincturae Sennae composite?, gj. / Direct a table-spoonful, mixed with double the quantity of water, as hot as it can be drunk, to be taken for a dose, in cases of violent pain of the stomach, where a cordial purgative is required; to be repeated pro re nata. Decoction of Aloes, /c,\ v' ""lJfnr . Oil of Jumper, fc./QJ ^y* ^ *\^Z\t.^ Nova 1395 "" Gummi arabici, 55. giss. Aquae destillatae, 3iv. >V^^'. ;-?Y ^ Misce et signa.—A table-spoonful to be taken eveTy hour cT two hours. Infusion of Juniper Berries, 4*c. R. Bacca? Juniperi contusae, Siss. Super-tartratis potassa?, 3j. Aqua? bullientis, Oj. Fiat infusio.—Of this a tea-cupful may be taken four or six times a-day; adding to each a tea-spoonful of the sweet spirits of nitre. In general and local dropsy. Mixture of Colchicum, Squills, fyc. R. Oxymellis Colchici, Scillae, Tincturae Nicotianae, aa. 3ss. M. Signa.—Take a tea-spoonful in a little water four times a-day. If requisite, the Spiritus setheris nitrici may be added in the same quantity. This forms the diuretic drops of Dr. Ferriar. Infusion of Digitalis, fyc. R. Foliorum Digitalis, 3j. Aqua? bullientis, Oss. Macerate for three hours, then strain.—Dose for an adult, a table- spoonful three times a-day. The prostrating effects of Digitalis should always be borne in mind by the practitioner; and the rule that DIURETICS. 51 when it acts upon the stomach, the bowels, the pulse, or the kidneys, it should be discontinued, cannot, when we consider the power of the article, be too scrupu- lously observed. Mixture of Digitalis, Potash, $c. R. Infusionis Digitalis, giv. Tinctura? Digitalis, gi. Acetatis Potassae, gj. Tincturae Opii, gtt. x. Fiat mistura.—Signa.—A table-spoonful three or four times a-day. Mixture of Spirits of Turpentine, Tincturae Castorei, 3ss. Syrupi Tolutani, ^ss. Tinctura? Opii, gtt. v. Aquae Cinnamomi, 5j. Fiat mistura.—Signa.—A small table-spoonful every three or four hours in troublesome cough. ^r- Mugs- Mixture of Morphia and Tolu. R. Oxymellis Scillae, ^iss. Syrupi Tolutani, fss. Acetatis Morphia?, gr. ij. Misce.—Signa.—A tea-spoonful may be taken every two or three hours, pro re nata. Useful in Phthisis pulmonalis, and other dis- eases attended with troublesome cough. Dr. Meigs. Tolu with Morphia and Antimony. R. Mucilaginis gummi Arabici, Oj. Syrupi Tolutani, ^ij. Morphia? sulphatis, gr. iss vel ij. Antimonii tartarizati, gr. ij. Misce, et signa.—A table-spoonful to be given every two hours. Morton on Consumption, page 123. Decoction of Seneka Root. R. Radicis Polygala? senega? contusae, ^j. ------Glycyrrhizae, 3ss. Aquae destillatae, Oiss. Boil down to a pint, and strain. This decoction is serviceable in pectoral diseases. In croup, the author has seen it productive of great benefit. INHALATION. Inhalation is a means of applying remedies directly to the lungs. EXPECTORANTS. 85 The best instrument for this purpose is the Inhaler of Mudge. As a substitute however, the common tea- pot may be used, or a funnel inverted over a bowl. The substances usually selected for inhalation are— The steam of warm water: The steam of vinegar, produced by pouring it into boiling water. Also, Balsam Tolu, as follows:— R. Balsami Tolutani, ?j. Aqua? bullientis, Oj. Misce.—To be inhaled in diseases of the lungs. Ether is also used alone, or impregnated. When saturated with cicuta, and inhaled from a wine-glass, it is said to be serviceable in protracted catarrh, pneu- monia, consumption, &c. Dr. Morton advises Dr. Pearson's formula, which consists in keeping a drachm of powdered cicuta in an ounce of ether for a week. A tea-spoonful or two of this impregnated fluid may be inhaled at a time, and repeated thrice per diem.— Morton on Consumption, page 136. Stramonium is an article recommended particularly in asthma and consumption. The root is cut, dried, and smoked from a common pipe. Fumigations of tar and turpentine are also recom- mended from high authority. The former is said to have cured consumption. It usually,is applied by placing the tar on a dish over coals, and suffering it slowly to evaporate:—but a far neater and more effec- tual mode is that practised by Sir Alexander Crichton, viz: " an ounce of potash is added to every pound of tar, in order that the latter may be deprived of its pyroligneous acid. The two ingredients being well mixed, should be first boiled for a few minutes in the open air, in order to disengage any impurities, and then be kept at a simmer in the room of the patient. This is effected by putting the mixture in an iron ves- sel, and placing the latter over a spirit lamp, or some 86 EXPECTORANTS. analogous contrivance. In this way, not only a cham- ber, but an entire house, is speedily pervaded by a most agreeable vapour, which, although it may at first excite some disposition to cough, both in healthy and sick persons, .very soon, in a majority of cases, allays this symptom, and with it a great proportion of the patient's distress."—Morton, ut supra. The fumes of resin are frequently employed by Dr. Parrish, of this city; he directs it to be put on a hot shovel, or coals, and allows the patient to inhale it gra- dually until it is ascertained whether it can be borne. To some persons it is very agreeable, while the lungs of others cannot tolerate it. He has found it beneficial in debility of the lungs, whether idiopathic or the re- sult of disease; and also advises it in pertussis and phthisis. In some cases of croup, the inhalation of ether or Hoffman's anodyne, will often procure the most prompt relief, and gain time for the application of general re- medies. Chlorine gas has also been much used by inhalation, not pure, however, but mixed or diluted with atmo- spheric air. For this purpose a little acid of any kind may be dropped gently on a mixture of chloride of lime, by which means the chlorine is gradually disen- gaged, and be inhaled as it rises; or, the air of a room may be charged with it in like manner. It has been much commended in Bronchitis and the kindred affec- tions, but is getting into disuse from its manifest want of efficacy.* * Fumigation oj Chlorine. gi. Muriatis Sodae, Ifcij. Oxidi Manganesii, gv. Aqu33, ft)j- Acidi Sulphurici, tbj. Mix the salt and manganese, and add at proper intervals the acid and water, mingled. When used in the wards of hospitals or other infected apartments, the patients should be previously removed. For the method of preparing the different chlorides used as disenfecting agents, see Journal of the Philadelphia College of Pharmacy, Vol. I. Ao. 4, EXPECTORANTS. 87 The following is Dr. Scuddamore's recipe for Iodine Inhalation: R. Iodinae, Iodidi potassii, aa. gr. vj. Aquae destillatae, gv 3vj. Alcohol, gj. Mix, and use for inhalation. " I usually commence with a drachm of this mixture, proceeding gradually to the extent of half an ounce, (rarely more,) putting two- thirds the dose for the first half of the time (10, 15, or 20 minutes,) and the other third for the remainder, always adding thirty minims of a saturated tincture of conium, with an increase if the cough be very irritable. Occasionally I add some saturated tincture of ipecacuanha; and when the respiration is spasmodically affected, some aetherial tincture of the lobelia inflata."—Scuddamore. ( 88 ) CLASS VII. EMMENAGOGUE S. Emmenagouges are those medicines which promote the menstrual discharge, or restore it when entirely suppressed. Although by some authors the specific action of these medicines on the uterus has been ques- tioned, if not denied, yet by others, whose authority is equally to be trusted, it has been fully acknow- ledged. It must, however, be observed, that amenorrhcea oc- curs under opposite states of the system; and where general debility appears to be the cause of the local dis- ease, it is advisable to accompany the emmenagogue with an active course of tonics. While, on the con- trary, if the obstruction be the effect of a plethoric habit, bleeding, cathartics, &c, are essential preliminaries to the exhibition and success of a specific remedy. POWDERS. Powder of Hiera Picra. R. Pulveris Hierae picrae, -Z]. Divide in chartulas vj.—One three times a-day. This article is placed under the head of cathartics, but it is a remedy so generally employed as an em- menagogue; that it appears necessary also to insert it here. EMMENAGOCTJES. <59 Powder of Madder. R. Pulveris Rubia? tinctori, 5ss. Signa.—A small tea-spoonful to be taken morning, noon' and night, in sugar and water. It should be remembered that there are three or four qualities of madder, which circumstance may account for the frequent failure of this remedy. Dr. Dewees frequently employs it. Powder with Savin, $c. R. Sabinae exsiccatae, Pulveris Zingiberis, aa. 3j- ------- Potassa? sulphatis, rij. Fiant pulveres vj.—Signa.—One to be taken twice a-day Powder with Savin and Cantharides, R. Pulveris Sabinae, 3ij- ------ Cantharidum, gr. ij. Misce et divide in pulveres iv.—Signa.—One to be taken every night, on going to bed. Powder of Spurred Rye. R. Pulveris Secalis cornuti, 9ij. Divide in chartulas iv—Of which one may be taken morning and night, in sugar and water. Drs. Chapman and Dorsey have placed this remedy under the head of Emmenagogues, though we are not aware that it has ever been successfully employed as such. Pills of Myrrh, Sulphate of Iron, fyc. R Gummi Myrrhae, Sulphatis Ferri, aa. 9ij. Carbonatis Potassae, Saponis purificati, aa. zss. Fiat massa, in pilulas xl. dividenda.—Of which two may be taken morning, noon and night. In that suppression of the catamenia which is incident to phthisis pulmonalis. 12 yo EMMENAGOGUES. Hooper's Pills. R. Sulphatis Ferri, 9j. Pulveris Senna?, ------- Jalapae, ------- Super-tartratis Potassae; aa. 9ss. ------- Zingiberis, gr. xij. Syrupi simplicis, q. s.—ut fiat massa, in pilulas xxv. dividenda. The patient is directed to take three twice in the day, followed by twenty drops of the tinctura ferri muriatis in a glass of some bitter infusion. This compound is sold by the apothecaries as a patent medicine. Pills of Aloes, Sulphate of Iron, fyc. R. Sulphatis Ferri exsiccati, 9j. Pulveris Aloes, 9ij. ------- Caryophylli, gr. v. Terebinthinae veneta?, q. s..—ut fiant pilula? xx.—Signa.—One to be taken three times a-day. DECOCTIONS, TINCTURES, &c. Decoction ofSeneka. R. Radicis Senega? contusae, ?j. Corticis Aurantiarum, ij. Aquae destillatae, Oj. Let the seneka simmer over a slow fire until the fluid be reduced one- third; add the orange-peel, cover until cool, and then strain. Dr. Chapman observes—" My rule in the adminis- tration of the medicine in these cases, (that is, of amenorrhcea,) is to give about four ounces of the de- coction, more or less, during the day, according to the circumstances of the case. But at the time when the menstrual effort is expected to be made, and until the discharge is actually induced, I push the dose as far as the stomach will allow, having given as much as two ounces every hour."—Therapeutics, Vol. II. p. 38. EMMENAGOGUES. 91 Infusion of Ergot. R. Secalis Cornuti contusi, 3ij- Aquae bullientis, 5vj. Fiat infusio.—To be given by spoonsful, in protracted parturition occasioned by deficiency of contractile power in the uterus. For the same purpose the powder may also be given in doses of 9j., as well as to assist in arresting uterine hemorrhage, and to cause the expulsion of the pla- centa. Decoction of Ergot. R. Secalis cornuti, 5j. Aqua?, Oiiss. Boil gradually down to two pints, and give a table-spoonful every fifteen minutes. Used in the same circumstances as the infusion. Tincture of Ergot. R. Secalis cornuti, giiss. Spiritus tenuioris, Oj. Macerate for fourteen days, and strain. This is the formula used in Guy's Hospital. Dose twenty drops to a dram. Sirup of Ergot. R. Secalis cornuti, gr. xx. Extracti Opii, gr. |. Syrupi simplicis, ^viij. M.__Dose an ounce (two table-spoonsful) pro re nata, in engorge- ment of the uterus. Lisfranc. Decoction of Madder. R. Pulveris Rubiae tinctori, ^j. Aqua? bullientis, Oj. Simmer for fifteen minutes—and add— Caryophylli contusi, 3j- Sjgna—When cool, strain and give a wine-glassful every three hours, a short time before the expected return of the menstrual discharge- See Dewees on Females, p. 74. 92 RMMEN AGOG LIES. Mixture of Camphor, fyc. R. Camphorae, 9j. Spiritus vini rectificati, q. s.—ut fiat pulvis: dein adde— Pulveris gummi Arabici, 3J- Sacchari albi, q. s. Aqua? Cinnamomi, ^j. Fiat mistura. This mixture would more properly appear under the head of Narcotics, but as Dr. Dewees considers it particularly efficacious in dysmenorrhoea, we have given it a place with Emmenagogues. He directs " one-half the above draught to be given the instant pain is experienced, and if not relieved in an hour or two, the remainder to be given."—Syst. Mid. p. 158. Tincture of Hellebore. R. Tincturae Hellebori nigri, gj. Signa.—A tea-spoonful three times a-day, increasing the quantity as the stomach will admit of it. Tincture of Hellebore, Myrrh, 4'C R. Tinctura? Hellebori nigri, gss. ------- Myrrhae, gj. ------- Cantharidum, 3ij. Fiat mistura.—The patient may take thirty drops, three times a-day, in a little sugar and water. Tincture of Savin, fyc. R. Tincturae Sabinae compositae, gj. ------- Hellebori nigri, gss. ------- Castorei, 51J. Fiat mistura.—Signa.—To take forty drops three times a-day, in any vehicle. Tincture of Guaiacwn, (Dewees.) R. Pulveris Guaiaci, giv. Carbonatis Soda? vel Potassa?, riss. Pulveris Pimentae, gj. Alcoholis diluti, ftsj. EMMENAGOGUES. 93 Misce.—" Digest for a few days.—The volatile spirit of ammonia to be added pro re nata, in the proportion of a drachm or two, to every four ounces of tincture." The above formula is different from' that adopted in the Pharmacopoeias, for which reason we have inserted it here. Dr. Dewees informs us, that after nearly thirty- five years' experience with this tincture, he has never known it to fail in restoring the suppressed catamenia, where the suppression was an idiopathic disease. He gives it morning, noon and night, in doses of a tea- spoonful in a little sweetened milk; and sometimes in a little Madeira, Sherry, or Teneriffe wine. It is oc- casionally necessary to continue the medicine for some weeks, on which occasion, the dose must be judiciously augmented.—Syst. Mid. p. 149. Volatile Tincture of Guaiacum, fyc. R. Tincturae Guaiaci volatilis, gj. Balsami Copaiba?, gss. Misce.—Signa.—A tea-spoonful two or three times a-day. In cases of amenorrhcea connected with general de- bility. Tincture of Iodine. R. Iodini optimi, 9ij. Spiritus vini rectificati, gj. Spiritus Lavendula? compositi, 3'j. Fiat tinctura.—Signa.—From ten to twenty drops twice a-day, gra- dually increasing it to forty drops. The above we are informed by M. Durand, apothe- cary of this place, is a saturated tincture. Dr. Bell has used it beneficially in amenorrhcea, gonorrhoea, leucorrhcea, &c. From its great activity, it requires to be cautious] v administered. Solution of Iodide of Potassa. R. Potassii Iodidi, 3j- Aqua? destillaLc, gj. 94 EMMENAGOGUES. Fiat solutio.—Signa.—Thirty drops of this solution is directed by Dr. Bell in the above cases.—See N. A. M. and S. Journal, Oct. 1828. Injection of Aqua Ammonias, $c. R. Aqua? Ammonia?, gtt. xx. Lactis recentis, gi. Misce.—Signa.—This quantity to be thrown into the vagina three or four times a-day in cases of amenorrhcea. Tincture of Cantharides, (Dewees.) This tincture, as prepared from the formula of Dr. Dewees, differs from that kept in the shops in strength only. Ten drops may be taken three times a-day, and gradually increased; and, if necessary, until strangury is induced. Mixture of Muriate of Iron, Sic. R. Tincturae Muriatis Ferri, -------Aloes compositae, aa. gss. -------Castorei, 3ij- Fiat mistura.—Signa.—Take a tea-spoonful three times a-day in a wine-glassful of camomile tea. Tincture of Hiera Pier a. R. Tinctura? Hiera? Picrae, gj. Signa.—A tea-spoonful may be taken three times a-day in sugar and water. Compound Tincture of Aloes. R. Tinctura? Aloes et Myrrhae, gj. Dose.—A tea-spoonful pro re nata. ( 95 ) CLASS VIII. ANTHELMINTICS. Anthelmintics are medicines employed to destroy and bring away worms from the alimentary canal. They are also termed Vermifuges. The only unequivocal proof of the existence of worms in the alimentary canal is the ejection of some of them per anum, or, as sometimes happens, by the mouth. When, in such cases vermifuges are resorted to, they must be persevered in for several days, with the occasional intervention of an active cathartic. POWDERS. Calomel with Gamboge. R. Hydrargyri Chloridi mitis, gr. v. Pulveris Gambogia?, gr. vj vel x. Misce.—For an adult.—To be taken in sirup early in the morning. Gamboge is sometimes given in doses of fifteen or twenty grains for the tape-worm, and is highly spoken of in such cases. Calomel with Pink-Root. R. Hydrargyri chloride mitis, gr. iv. Pulveris Spigeliae, gr. x. Misce.—Signa.—To be taken two mornings in succession, and on the afternoon of the second day, followed by a dose of castor oil or senna and manna.—For children upwards of four years old. 90 anthelmintics. Pink-Root with Savin. t\-c. R. Pulveris Spigeliae, ------- Senna?, aa. 9ij- ------- Sabina?, gr. xij. Fiant chartulaevj.-Signa.-One every morning till three are taken, then give a dose of castor oil; if the effect is not produced, the remainder may be exhibited after the same manner. Common Salt with Cochineal. R. Sodii Chloridi, siij. Coccinella? pulverizatae, gr. xv. Fiant doses vj.—Signa.—One every morning, following the last dose with some purgative medicine. Dr. Rush speaks in high terms of this remedy. Carbonate of Iron. R. Carbonatis Ferri, 3J. Divide in chartulas iij.—One powder to be taken before breakfast. Of this remedy, also, the late Professor Rush had a very favourable opinion. He gave it in doses of from 5 grs. to 3SS. to children of from one year old to ten, and sometimes in half ounce doses, with safety and success. It is chiefly used in tape-worm.—See Observ. and Inquiries, p. 243. Powder of Male Fern. Give of the powder of the Male Fern Root from one to three drachms, in a large cupful of any distilled water, early in the morning. If the stomach should reject it, the powder must be repeated again, as soon as the sickness has gone off, in the same quantity. When it has been upon the stomach about two hours, a strong cathartic bolus made of calomel and gamboge, (eight or ten grs. of the last and five or six grs. of the first,) must be taken, and worked off with a draught of green tea every now and then: and its operation may be still farther promoted, if necessary, by half an ounce, or 3VJ. of salts, dissolved in warm water. Till the worm comes away, which ANTHELMINTICS. 97 generally happens on the same day, the patient is to take nothing but broth. If, however, the worm should not be discharged, either wholly or in part, the powder is to be repeated with the same regimen, the next day. In the tape-worm.—Nouffer. It has been suggested, and with some probability, that the purge directed to follow this remedy is that on which the greatest reliance is to be placed. Tin Electuary. R. Pulveris Stanni, 3yj vel gj. * Sacehari liquidi, giv. Misce.—Two or three table-spoonsful may be given early in the morning; to be repeated until the whole be taken, and then fol- lowed by an active cathartic. The efficacy of this remedy is said to be increased by combination with sulphur, by which means sul- phuretted hydrogen would be generated, and the worm destroyed by this offensive gas. Larger doses than those mentioned are sometimes prescribed. Cowhage Electuary. R. Spicularum Dolichi, 3J. Mellis liquidi, q. s.—ut fiat electuarium.—Dose, a lea-spoonful to a child two or three years old; to be given before breakfast in the mornings of three successive days, and then followed by a brisk cathartic. In Lumbrici. Vermifuge Bolus. R. Hydrargyri Chloridi mitis, gr. ij. Seminum Artemisia? santonicae, gr. viij. Camphorae, gr. vj. Syrupi, q. s.—ut fiat bolus. To be repeated pro re nata—for children of four or six years of age. Ratier's Formulary. * Molasses. Any sirup will, of course, answer the same purpose. 13 98 ANTHELMINTICS. INFUSIONS, DECOCTIONS, &c. Infusion of Pink-Root, #c, vulgo, Worm-Tea. R. Radicis Spigeliae Marilandieae, gss. Senna? foliorum, 3IJ. Mannae optimae, gj, Seminum Fceniculi, 3U vel gss. Aquae bullientis, Oj. Fiat infusio.—Signa.—A wine-glassful may be given to a child of two years old, three or four times a-day. Pills of Venice Turpentine, &/c. R. Terebinthina? venetae, 3J. Extracti Hyosciami, gr. iv. Hydrargyri Chloridi mitis, gr. viij. Fiat massa, et divide in pilulas singulas gr. ij. Of these four are to be taken every three hours, and during the entire period, the patient is to take only weak broth, tea, or coffee. They are strongly recommended by some of the German practitioners in tape-worm. Infusion of Pink-Root. R. Radicis Spigelia, 5j. Aqua? bullientis, Oj. Fiat infusio.—Of which a child may take from one to two table- spoonsful at a dose; an adult from gj to giv. The spigelia sometimes affects children violently; hence the necessity of caution in its use. Decoction of the Geoffrea Bark. R. Corticis Geoffrea?, 5j. Aquae Oij. To be boiled over a slow fire until it assumes the colour of amber or Madeira wine.—Dose for adults four table-spoonsful; for children two or three years old, one table-spoonful; and so in proportion to ANTHELMINTICS. 99 the age and strength of the patient.—The dose of the extract of this medicine is stated by Dr. Chapman to be three grains, and of the powder, 3SS. We are not aware that the remedy has been much employed in this city. Cold water is to be avoided while using this decoction; if, however, any unpleasant consequences follow its exhibition, and particularly where an overdose has been given, our best resource is Oleum Ricini, together with tepid water acidulated with lemon juice, or some other vegetable acid. Mixture of Worm-seed Oil. R. Olei Chenopodii, 3j' Sacchari albi, Gummi Arabici, aa. jiss. Misce, secundum artem; tunc adde— Aquae Mentha? sativae, gijss. A tea-spoonful of this preparation may be given four times a-day for two days in succession, and then purged off with castor oil or salts.— For children of three to eight years old. This is a vermifuge of considerable reputation in this country. It is generally used in Lumbrici and Ascarides ; though we have heard of its having been successfully given for Tenia, but in much larger doses. Spirit of Turpentine. Is recommended for Tape-worm, in doses of 3ss to gij. daily, taken in honey. Dr. Chapman speaks highly of this remedy; and the safety of such doses seems to be now fully esta- blished. Olive Oil and Ammonia. R. Olei Olivarum, gviij. Spiritus Ammoniae aromatici, gij. Dose, three spoonsful night and morning. 100 ANTHELMINTICS. This remedy is highly spoken of by some authors, and may be given in much larger quantities; if it should not purge, it will be necessary to follow it with some aloetic or other cathartic preparation. Decoction of the Bark of Pomegranate. R. Corticis radicis Granati, 3ij. Aqua? destillatae, Oiss. To be boiled away one-half, and given in doses of an ounce several times in the day. " The efficacy of the bark of the root of the Pome- granate," says Dr. Ainslie, (Mat. Med. of Hindoostan,) "asa remedy for the tape-worm, is now well established in India."—Paris, vol. ii.p. 173. Aloetic Enema. R. Gummi Aloes, 31J. Lactis recentis, Oj. Fiat enema.—The half of this may be given to a child eight or ten years old. In Ascarides. Spirits of Turpentine with Hartshorn. R. Olei Cornu Cervi fcetidi, gss. ---Terebinthinae, 5iss. Misce, et signa.—A tea-spoonful to be given every morning. In taenia. - '. • '- ' ■....« [M. Chabert. Spirit of Turpentine, Ether, &c. R. Olei Terebinthinae, gss. iEtheris sulphurici, 3ij. Pulveris gummi Arabici, gss. Aquae Chamaemelae destillatae, gxvj. Misce, et signa.—Two table-spoonsful to be taken morning and even- ing. In taenia. Dr. Frank. Enema of Camphor, fyc. R. Camphorae, gj. Olei olivarum, 3ij. Misce pro enemate. ANTHELMINTICS. 101 This preparation is particularly adapted to Ascarides, and should be freely thrown up the rectum for three or four successive nights. No remedy is more effect- ual than this in relieving the intolerable itching caused by those worms. Enemata are the most certain of all remedies in As- carides; they may be made of various substances, such as solution of asafoetida, of common salt, hepar sulphu- ris, pure olive oil, soap, &c. &,c. ( 102 ) CLASS IX. EPISPASTICS. " By the ancients, all the external applications which redden or inflame the skin, were called Epispastice, and these were designated according to the several degrees of effect:—the slightest, entitled phoenigmoi; the next, sinapismi; the more active, vesicatorii; and the strongest, caustict.,> We shall, however, as heretofore, follow the arrange- ment adopted by Dr. Chapman, and divide them into Rubefacients, Blisters, and Caustics; and with him too, we shall first speak of Blisters. As a general rule, blisters should remain on the pa- tient ten or twelve hours, in order to ensure their full effect. There are individuals, however, whose skins are so delicate, that a shorter application will answer every purpose; in children, it is seldom, and perhaps never, necessary to leave them on longer than four or six hours. When they are applied to the scalp, twenty- four hours is almost universally required; and Dr. Chapman directs the hair to be shaved, if possible, some hours before the application is made. The usual dressing, when a blister is taken off, is basilicon ointment, or ceratum simplex, according to the urgency of the case, or the irritability of the sys- tem. In order to keep it open, the weak epispastic, or savin ointment, will be found sufficient. EPISPASTICS. 103 In cases of acute disease, these remedies ought never to precede those means which have a tendency to re- duce the system. It is generally admitted, that other- wise employed, they do harm, though there are indi- viduals of acknowledged experience who say, "they can bring a patient to the blistering point at pleasure;" and in pleurisy, and some other acute diseases, apply them soon after a free bleeding. The blister should be placed as near the affected part as possible. In fevers they are usually put on the inside of the forearms or legs, back of the neck, or between the shoulders. Where the system is very prostrate, they should be applied to the inside of the thighs, or the last two places mentioned: for when the circulation is very languid in the extremities, they seldom draw well, and are even liable to produce gangrene by exhausting the little vi- tality that remains. Where, from peculiarity of constitution, strangury is produced by them, we must take them off after a few hours, and bathe the part wTith sweet oil or some such mild application—if this prove insufficient, resort must be had to diluent drinks, such as flaxseed tea or barley water, with the sweet spirits of nitre; camphor or pars- ley tea, or bladders half filled with warm water and applied to the pubes. An opium suppository or in- jection will be found very advantageous. A poultice of ground flaxseed or starch is often very serviceable. Prevention, however, is better than cure; and in irrita- ble constitutions, or in persons disposed to strangury, the blistering ointment, before being spread, should be rubbed up with three or four grains of opium and three or four times as much camphor, before it is spread. This preventive seldom fails. Blisters are rendered much less irritating by covering them with a fine gauze, which, if it be pressed in close contact with the plaster, will not prevent or materially retard its operation. It is said by some writers, that if a blister be sprinkled with powdered camphor, previous to its application, strangury will never result: this precaution cannot 104 EFISPASTICS. always be relied on, though it will be well to give it a trial where strangury is anticipated. Epispastic Ointment. R. Cera? flavae, Resina?, Axungiae Porcinae, aa. 5vj. Melt over a slow fire, and when at the temperature of 98° add slowly-— Pulveris Cantharidum, gvijss. Misce, et fiat unguentum. If the cantharides be united with the melted plaster before it is partially cooled, they are liable to be injured by the heat. In employing this ointment, the margin of the blister should be covered with adhesive plaster, in order to confine it to its place, and prevent its creating unneces- sary irritation. Another mode is to draw straps across it diagonally, which plan we generally prefer; it pre- vents the blister from rising in the middle, and thereby partially defeating its object. It is mentioned in Paris' Pharmacologia, that the flies may be deprived of their power of producing stran- gury by first boiling them in water. RUBEFACIENTS. The substances called Rubefacients not unfrequently vesicate on very delicate skins. The term, therefore, is relative. They are employed for the same purpose as Blisters, and are often good substitutes for them. Plaster of Mercurial Ointment, Camphor, $*c. R. Unguenti Hydrargyri, gj. Olei Terebinthinae, Camphorae, aa. 2ij. Cerati simplicis, ij. Fiat unguentum secundum artem. Used as a rubefacient over the hy- pochondriac region, when blisters are precluded. EPISPASTICS. 105 Tartar Emetic Plaster. This may be made by sprinkling the powdered Tartrate of Antimony on the surface of a Burgundy pitch or adhesive plaster, or on one made by spreading Basilicon, or simple ointment, on leather or linen. In either way the margin should be left clean. This remedy requires a longer time to produce its effect than the ordinary blister; the irritation is of a peculiar and very painful kind. Tartar Emetic Ointment. R. Tartratis Antimonii, 3j. Axungia? Porcinae, gj. Misce secundum artem. This ointment, when applied to the skin, is a slow but certain means of exciting an eruption. We have given the formula of Dr. Hannay, of Glasgow, in Scot- land. Dr. Jenner recommended a much larger propor- tion of the antimony. Tartar Emetic and Corrosive Sublimate. R. Tartratis Antimonii, ^j. Chloridi Hydrargyri, gr. v. Aqua? destillatae, gj. Spiritus Lavandulae compositi, 3j. Solve sales in aqua, dein adde spiritum. This solution is applied by wetting the fingers with it, and rubbing it on the part. The rubbing should be continued for five or ten minutes, and after some hours a pustular eruption will appear.—Dr. Hannay's essay, " De Tartratis Antimonii Usu Externo" p. 26. It has been extolled in pertussis, dyspnoea, cough, pains in the chest, &c, and in the removal of incipient tumours. It has been ascertained by the illustrious Jenner and others, that Tartar Emetic employed for an undue 14 106 EPISPASTICS. length of time externally, will produce violent effects upon the system. We find in a note in Beck's Medical Jurisprudence, vol. ii. p. 283, that Dr. Francis mentions two cases where Tartar Emetic Ointment, excessively used, pro- duced effects similar to those at times arising from the outward application of arsenic. Majendie and Brodie ascertained by experiments upon animals, that inserted into wounds its effects resemble those produced by internal exhibition. Granville's Ammoniated Counter-irritant, or Antidynous Lotions, These preparations act with great celerity, and are now in common use. They are formed of three ingredients, mixed in certain propor- tions, according to the urgency of the case. 1. The first ingredient is the strongest liquor of ammonia (liquor ammoniae fortissimus) which is made by saturating a given quantity of distilled water, contained in a glass receiver surrounded by ice, with ammoniacal gas, obtained in the usual way from a mixture of equal parts of hydrochlorate of ammonia and recently slacked lime, both reduced to a fine powder. The water, by this process, may be made to take up nearly eight hundred times its bulk of ammoniated gas, and is three times the strength of the liquor ammonia? of the London Phar- macopeia. 2. The second ingredient is distilled spirits of Rosemary, prepared by taking two Jfos of the tips or small leaves of fresh Rosemary, and eight pints of alcohol, which are infused together for twenty-four hours in a covered vessel, and after adding as much water as will first prevent the empyreumatic smell, distil over seven pints. 3. The third ingredient is spirit of camphor, made as follows: To four oz. of pure camphor, add two pints of alcohol, so as to dissolve the camphor, which solution should be filtered. Of the preceding ingredients, Dr. Granville prepares two ammo- niated lotions, differing in strength; viz. The Milder Ammoniated Lotion. (Lotio ammoniata mitior.) R. Liquoris ammonia? fortissimi, 3j. Spiritus rosmarini, 3vj. ------camphorae, 5ij, Misce, EPISPASTICS. 107 The Stronger Ammoniated Lotion. (Lotio ammoniata fortior.) R. Liquoris ammonia? fortissimi, 3x. Spiritus rosemarinae, gss- ------- camphora?, 3ij. Misce.* As to the method of applying these counter-irritants, we shall use the words of their inventor, Dr. Granville. " First impregnate with the colourless and transparent liquid, either a piece of linen folded six or seven times to the size of the part intended to be covered, or a piece of thick and coarse flannel; and, secondly, lay either of them on the spot, pressing with the hand at the same time, very steadily and firmly, the said linen or flannel, over which there should be placed a thick towel, doubled several times, so that not only the evaporation of the lotion may be impeded, but the hand employed in pressing the application to the part may not suffer damage from any evaporation, or from contact with the liquid. In some parts of the body more con- venient than the others, the readiest and most effectual mode of press- ing down the application is, by tying over it a towel or thick bandage; but to this mode there is the objection that we cannot, under certain circumstances, infect the part as quickly and as often as required, so as to judge, from the effect of the application, when to stop, or how long to persevere in using it."t When applied to the temples, forehead, jaws, or chin, great care must be taken to prevent the effluvia from affecting the eyes and nos- trils. The skin should be examined in a minute or two after the ap- plication, in order to see the effect produced. When the pain is severe after the lotion is removed, simple diluent washes, and warm water is perhaps the best, will speedily allay it. Vesication will generally take place in from two to five minutes, and even in a minute in some persons: but where cauterization is requisite, ten, or twelve minutes may be necessary. The irritated or denuded surface may be dressed according to existing indications, with a simple poultice, tepid fomen- tation, cerate or irritating ointments. -The Pommade Ammoniacale of M. Goudret, which belongs to this series of counter-irritants, is made as follows: * Dunglison, New remedies, p. 504. i Granville. Counter-irritation, its Principles and Practice, p. 39. 10^ KrixrANTICS R. Adipis, 3vij. Olei amygalarum, ^iss. Ammoniae liquidae (25°) 5vj> Melt the lard, mix the oil with it, and pour them into a wide- mouthed, vial with a glass stopper; then add the ammonia, close the bottle, mix the contents together by shaking, and keep the mixture in a cool place. If the skin is to be excited, perspiration to be re-esta- blished, or some sub-cutaneous engorgement to be dissipated, light and hasty practices accomplish these objects. If a rubefacient effect is desirable, spread the ointment thickly on linen, and apply it for one or two minutes. For vesication, continue the application for five or six minutes; and by a farther continuance, absolute cauterization is speedily produced. These powerful preparations are used in a great variety of diseases, and in all cases when speedy and powerful counter-irritation is de- manded; as in Neuralgia and rheumatic affections generally, both acute and chronic; spasms, convulsions, gout, paralysis, inflammatory dis- eases of internal organs, diseases of the heart, sprains, Sic. Sic. Instantaneous Vesication. The French practitioners have a process for raising an instant blis- ter. A piece of linen or paper being cut to the requisite size, is im- mersed in spirits of wine or brandy, or even cologne water, or spirits of camphor, whichever is most readily obtained. It is then laid on the part to be blistered, taking care that the moisture does not wet the surrounding surface. The flame of a lighted taper is then applied quickly over the surface of the paper, so as to cause ignition, which is almost instantaneous. At the conclusion of this operation, the cuticle is found detached and raised from the true skin beneath. Ointment of Iodine and Calomel. R. Iodini, partem j. Hydrargyri chloridi mitis, partem iss. Axungiae, partes xlviij. The iodine to be first united to the lard, and then the calomel added. MM. Plane and Souberain, by whom this ointment is proposed, state that these are the only proportions that can be used, without leading to decompositions that will defeat our intentions. EPISPASTICS. 100 Ointment of Protoiodide of Mercury, Sic. R. Protoiodidi Hydrargyri, gr. vj. Acetatis Morphia?, gr. viij. Axungiae, gj. Misce, fiat unguentum. Recommended by the French physicians in glandu- lar swellings. The morphia is believed by them to prevent the unpleasant effects of iodine when used in the shape of ointment. Pelletan. Ointment of Protoiodide of Mercury. R. Protoiodidi Hydrargyri, 9j. Axungiae, giss. Fiat unguentum.—Used to accelerate the cicatrization of inveterate venereal ulcers. An ointment may be made in the same proportions of the deutoiodidc of mercury. Of course to be used with more caution. Ointment of lodate of Zinc. R. Iodatis Zinci, 3j- Axungiae, gj. Fiat unguentum.—A drachm to be rubbed on the tumour twice a-day. Dr. Ure recommends the above as a substitute for the ointment of hydriocate of potassa in glandular swellings. Ointment of Hydriodate of Potash. R. Hydriodatis Potassae, 9j. Cerati simplicis, gj. Fiat unguentum. To be applied to scrofulous swellings, where the skin is unbroken. 110 EPISPASTICS. Iodine Ointment. R. Deuto-iodureti hydrargyri, gr. xv. Adipis preparatas, gij. Olei limonis, gtt. xx. Fiat unguentum. Employed as a curative application to syphilitic tubercles, chronic ulceration and other sequella? of venereal. Its great activity re- quires caution in its use. Ralxer. Simple Iodine Ointment. R. Iodinae, gr, iij. Adipis, ^ij. Fiat unguentum. Used as the preceding preparation. Iodine Liniment. R. Linamenti saponis compositi, %\. Tinctura? Iodinae, 3J. Misce. Ointment of Iodide of Potassium. R. Potassae iodidi, 3SS« Adipis, giss. Ut unguentum.—For Tetter and the kindred eruptions. Lugol's Ointment of Ioduretted Iodide of Potassium. R. Iodinae, gr. xij. Potassae iodidi, 9iv. Adipis, gij. Fiat unguentum.—Used in scrofulous opthalmia, ulcers, Sic. Ointment of Ioduretted Iodide of Potassium with Opium. R. Iodinae, gr. xvj. Potassa? iodidi, 3J. Tincturae opii, 3ij- Adipis, gij. Fiat unguentum. Applied to scrofulous and other ulcers.—Lugol. EPISPASTICS. Ill Ointment of Iodide of Arsenic. R. Iodidi arsenici, gr. iij. Adipis preparatae, gj. Fiat unguentum. Employed in Lepra, Impetigo, and other cutaneous affections. Ointment of Cyanide of Mercury. R. Hydrargyri Cyanidi, gr. xij. Adipis, gj. Fiat unguentum. Ointment of Iodide of Sulphur. R. Iodureti Sulphuris, partes 5. Adipis, partes 96. Fiat unguentum.—In Diseases of the Skin. Magendie. Ointment of Bromium. \\. Adipis, |j. Hydrobromatis Potassae, gr. xxxiv. Fiat unguentum. Decoction of Turpentine and Cantharides. ^^^ R. Pulveris Cantharidum, ±i. Olei Terebinthina?, 5viij. Boil them together for three hours, then filter. This is the process usually followed by our apothe- caries, but we conceive thirty minutes' boiling would be quite sufficient, and the cantharides be less likely to be injured by the heat. It was first made by Dr. Hartshorne of this city, wTho has used it with great success in the typhoid state of fever. It is merely rubbed over the surface of the body. Kentish Ointment. R. Unguenti Resinae flavae, gij. Olei Terebinthina?, 5>j' vel gss. Fiat unguentum. 112 EPISPASTICS. This preparation has long been celebrated in burns and scalds. We must be careful to avoid touching the sound skin, for turpentine occasionally inflames it severely. Turpentine Liniment. R. Olei Terebinthinae, gij. ---Olivarum, gij. Tinctura? Camphorae, gj. Aquae Ammonia?, 5j- Fiat linimentum. Creosote Ointment. R. Creosotis, gtt. xv. Cerati simplicis, gj. Olei cinnamomi, gtt. vj. Fiat unguentum.—In ulcers of a chronic character, and in cutaneous eruptions. Digestive Ointment of the French Hospitals. R. Unguenti terebinthina? comp. gij. Vitellum ovi j. Olei olivarum, gij. Misce.—Used in dressing indolent wounds and ulcers. Ratier. Sulphur Ointment. R. Adipis suilli, fly. Sulphuris sublimati, gviij. Fiat unguentum.—Used in friction—three to six drachms at a time. Mercurial Cerate. R. Unguenti Hydrargyri, 3iv. Cerati simplicis, gx. Fiat unguentum.—A dressing for venereal ulcers. Ratier. Ointment of Belladonna. R. Extracti Belladonna?, gij. Aquae destillatae, gij. Adipis Suillae, 5ij. Misce.—Employed by M. Chaussier as a direct application to the neck of the uterus, in case of rigidity of that part. Ratier. RUBEFACIEiYPs. 113 Liniment with Camphor, Sic. R. Spiritus Camphorati, 3iij. Acidi acetici fortis, ?j. Fiat embrocatio.—To be applied to bruises, rheumatic parts, &c. Soap Liniment, Sic. R. Liniment! saponis, 3>j. Aquae Ammoniae, 5j. Tincturae Opii, 3ss. Fiat linimentum.—To be used as above. Liniment with Ammonia and Olive Oil, vulgo, Volatile Liniment. R. Olei Olivarum, Aquae Ammonia?, aa. 5j. Misce.—This preparation is frequently employed in inflammation of the throat and other similar cases. Liniment of Ammonia and Tartarized Antimony. R. Linimenti Ammonias, gj. Tartratis antimonii, gj. Misce.—This is often applied to indolent tumours, and other swell- ings. Liniment of Cantharides, Sic. R. Camphorae, giij. Solve in decocti Cantharidis cum terebinthina, gss.—et adde__ Unguenti Hydrargyri fortis, --------simplicis, aa. X}. Fiat linimentum.—This preparation might be employed in cases of low fever, where it is desirable to rouse the system, and at the same time affect it with mercury; also in tumours. Lotion of Cyanide of Potassium. R. Potassii cyanidi, gr. xij. Mistura? amygdalarum, gvj. Fiat lotio.—Used in Lichen, and other chronic eruptions, 15 114 RUBEFACIENTS. Solution of Caustic Potash. R. Potassae purae, giss. Aquae destillatae, ^ij. Fiat solutio.—Signa.—To be applied to the spine in cases of tetanus. Dr. Hartshorne speaks in high terms of the benefi- cial effects of this solution in the above disease. The best mode of applying it, so as merely to produce a rubefacient action, is to tie a piece of sponge to a stick or common table fork, and use it as a brush to apply the solution from the nape of the neck to the sacrum. When the solution is tolerably strong, the effect is powerful. Compound Opiate Liniment. R. Tincturae Opii, Spiritus iEtheris Sulphurici, -------Camphorae, aa. gij. Fiat embrocatio.—To be applied to parts affected with rheumatism. It is very useful in odontalgia, pain in the region of the ear, &c. Opiate Liniment. R. Olei olivarum, gij. Tinctura Opii, gij. Aquae acetatis plumbi, ^ss. Misce. Embrocation of Acetate of Ammonia. R. Ammonia? carbonatis, gij. Acidi acetici, Oiij. vel q. s. ad saturandum: Spiritus tenuis, Oiss. Mix the ammonia with the vinegar, and after effervescence ceases, add the spirit. To be applied to rheumatic affections; or mixed with linseed meal, it may be used as a poultice to chronic inflammations of the joints, &c. RUBEFACIENTS. 115 Compound Liniment of Tar. R. Petrolei Barbadensis, gj. Camphorae, ?ss. Alcoholis, gtt. xl. Fiat linimentum.—Powder the camphor by adding the spirit, and then mix the whole in a mortar. To be applied round the joints in cases of a chronic kind, and especially where thickening of the liga- ments is suspected. Creosote Liniment. R. Creosoti, gtt. x. Olei Olivarum, gj. Fiat linimentum.—In Herpes, &c. Creosote Lotion. R. Creosoti, gtt x. Aceti, gij. Aquae destillatae, 5ij. Fiat lotio.—Applied in phagadenic ulceration. Camphorated Oil. R. Camphorae, gj. Olei Olivarum, 5iv. Tere, et fiat solutio; tunc adde, Olei Terebinthinae, ^iss. To be applied by rubbing with a piece of flannel; in deep-seated rheu- matic pains. Epithem with Tincture of Cantharides. R. Pulveris Cantharidum, gj. Spiritus vini rectificati, 5iv. Digest with a gentle heat for two days.—Strain and add— Camphorae, ±ss. To be rubbed on the parts affected. In paralysis. 116 CATAPLASMS, &C. Epithem with Camphor and Carbonate of Ammonia. R. Spiritus Camphorati, ^iv. Carbonatis Ammoniae, gss. Olei Juniperi, --- Succini, aa. gij. Misce.—To be employed in the same cases as the former. Liniment of Oil of Amber, fyc. R. Olei Succini rectificati, gij. ---Olivarum, 5ss. Tincturae Opii, gij. Spiritus vini Gallici, 5iij. Fiat linimentum.—Signa.—To be rubbed between the shoulders. In pertussis. Cayenne Pepper and Alcohol Dilute. R. Pulveris Capsici, gij. Spiritus vini diluti, 3viij. Misce.—This preparation forms an excellent rubefacient in cases of low fever. Dr. Chapman recommends it strongly in sciatica, and other rheumatic affections. In dyspepsia, and some diseases of the head attended with cold feet, socks dusted with Cayenne pepper are very useful. CATAPLASMS, Sic Cataplasm of Pepper, tf-c. R. Seminum Sinapeos contus: ftss. Piperis nigri, Pulveris Zingiberis, aa. 3j. Syrupi simplicis, q. s. ut fiat cataplasma. To be applied to the region of the stomach in severe pain or sickness; or, to the soles of the feet when revulsion is desirable. CATAPLASMS, &C. 117 Spice Plaster. R. Pulveris Caryophillorurn, ------• Cinnamomi, —----• Capsici annui, aa. gss. Misce, et adde— Farina?, Vini Gallici, aa. q. s.—ut fiat cataplasma. Let the plaster, thus prepared, be made hot, and applied to the epigas- tric region. Dr. Parrish was accustomed to speak in the highest terms of this plaster in cholera. Mustard Cataplasm. R. Pulveris Sinapeos, 3ij. Acidi acetici tepidi, q. s.—ut fiat cataplasma. The uses of the mustard poultice are too well known to require description. We will only observe, that it is frequently made by adding an equal quantity of wheat or rye flour; this should always be done for children, or other persons of delicate skins. It cannot, generally, be borne longer than a half hour or hour. Iodine Cataplasm. R. Tinctura? Iodinae, ^ss. Pulveris lini, 3J. Farina? avenae, iriij. Aqua? q. s.—ut fiat cataplasma. Applied to indolent ulcers, (especially those of a scrofulous character) and to tumours of the same class. Garlic Cataplasm. The Garlic Cataplasm is employed with the same intention as the mustard, though it is much less active. It may be made by bruising the cloves of garlic, and mixing them in a common poultice of bread and milk. Onions may be substituted for garlic. 118 CATAPLASMS, &C. Cataplasm of Common Salt, &/c. R. Pulveris Lini, Mica? panis singulorum partes aequales, Aqua? Soda? muriatis saturatae, q. s.—ut fiat cataplasma. To be applied to indolent strumous swellings, and enlargements of the joints. When it produces irritation or inflammation, the common bread and milk poultice must be substituted; and the other re-applied when the skin will admit of it Cataplasm of Vest. R. Farina?, ftj. Cerevisia? fermenti, Oss. Misce.—This cataplasm is useful in stimulating foul ulcers and gan- grenous wounds, and removing the unpleasant odour. It should be made with fresh yeast, and applied warm. Cataplasm of Charcoal. This cataplasm is made by stirring into the common bread and milk poultice as much finely powdered charcoal as it will bear. It is a very useful application to offensive ulcers; removing in a short time the fcetor, and disposing them to a more healthy aspect. Cataplasms are made of carrots or turnips, by simply boiling them to softness, and beating them to a pulpy mass. Both of these are said to furnish a good poul- tice for cancerous and other painful sores. Cloves. Quilt some powdered cloves in flannel, and wring them out in hot brandy. Thus prepared, they form an excellent external applica- tion in cases of colic, and great irritability of the stomach, as it occurs in cholera. Emollient Cataplasm. R. Farina? seminum Lini, --------------Hordei, aa. partes equales. Aquae vel lactis, q. s.—ut fiat cataplasma. The milk or water may be warmed if desirable. Applied to inflam- matory tumours. BATHS, FOMENTATIONS, &C. 119 Antiseptic Cataplasm. R. Cataplasmatis emollientis, 3viij. Pulveris Kino, ------. Camphorae, aa. gij. Fiat cataplasma.—Applied to wounds and ulcers that have assumed an unhealthy action. Hotel Dieu. Resolvent Cataplasm. R. Cataplasmatis emollientis, giv. Acetatis plumbi, 3j. Muriatis ammonia?, gss. Fiat cataplasma.—Applicable to tumours that require a gentle excite- ment. Ratier's Formulary. Warm Strengthening Plaster. R. Picis Burgundici, 3v. Unguenti Cantharidum, 3j. Fiat emplastrum.—This plaster is applied in the same way, and used in all the cases for which Burgundy Pitch is prescribed. It is irri- tating, and on some persons will draw a blister. BATHS, FOMENTATIONS, &c. The ordinary application of cold, tepid and shower baths is too well known to require any particular no- tice. The hot bath should be of a temperature of 93 to 96 degrees of Fahrenheit. It is designed to alleviate general or local irritation, and to induce repose and sleep. It is especially adapted to fevers with deficient capillary circulation, rheumatism, herpetic eruptions, paralytic affections, &c. The lower temperature is best adapted to cutaneous complaints, and to bring on relaxation of the skin during febrile irritation: the warmer temperature is suited to paralysis; and, as a general rule, more heat is desirable to act upon deep seated than on superficial diseases. Vapour Baths are produced by the evaporation of boiling water in a suitable apparatus. They are used, like ordinary warm baths, in rheumatic and cutaneous 120 BATHS, FOMENTATIONS, &C. affectons and in every case wherein profuse perspira- tion is desirable. They are avoided in persons labour- ing under pulmonary or cardiac disease, and in cases of exhaustion from any cause. Local Baths are admirably adapted to parts which are swelled and painful, and may consist of tepid water only, or their strength may be increased by the addi- tion of saline, emollient, narcotic or stimulant sub- tances. Sulphurous Water, or Artificial Bareges Bath. R. Sulphureti Potassa?, jfoj. Aquae, cong. xxx. Mix for a bath. In cutaneous eruptions. Sulphureo-Gelalinous Bath. R. Sulphureti Potassae, gij vel giv. Aquae, cong. xxx. Add to this solution, Ichthyocollae, fkj. vel ifeij i*1 Aquas bullientis solutae, J^x. This bath, according to Dr. Green, (Diseases of the Skin, p. 240,) " is preferable to the artificial Bareges Bath, as it is neither irritating nor apt to occasion feverishness, which the common sulphureous water bath is. A cheaper and not less efficacious gelatine may be procured by dissolving from a pound and a half to two pounds of parchment-clippings in water by long boiling, or by using a neat's or a calf's foot for the purpose." Emollient Bath. To an ordinary tepid water bath, add a large cupful of thick gruel or paste, and mix it well with the water. These baths are very effica- cious in prurigo, eczema, lichen and impetigo. Nitro-murialic Acid Bath. R. Acidi nitrici, 3iij. Acidi muriatici, 3j. Mix, and add to the water of a tepid bath, which should then be about as sour as distilled vinegar. BATHS, FOMENTATIONS, &C. 121 Sublimate Bath. R. Hydrargyri bichloridi, gij vel gj. Aqua? tepidae, cong. xxx. Mix for a bath. Prescribed by the French physicians in syphilitic affections, when it is desirable to avoid the action of the medicine on the stomach. This plan is seldom resorted to, on account of the great risk of employing corrosive sublimate in such large quan- tity. Alkaline Bath. R. Potassae carbonatis, giv vel gviij. Aqua? tepidae, cong. xxx. Mix for a bath. Very useful in promoting desquammation from the skin, and in allaying itching in various forms of Prurigo. Artificial Harrowgate Bath. R. Soda? muriatis, tfoij. Magnesiae sulphatis, giij. Potassa? sulphureti, ffoj. Aqua?, cong. xxx. Mix for a bath. Fomentation is a yet more restricted mode of ap- plying fluids to the surface of the body, which is done by means of a sponge, flannel or soft cloth. To be efficacious they should be often repeated, and not allowed to get cold. Stimulant Fomentation. R. Vini rubri, Oij. Mellis, giv. Misce.—This is an active fomentation, and is applied to parts in a low state of vitality. Ratier. Saponaceous Fomentation. R. Spiritus vini gallici, Oij. Saponis, 3J. Misce.—A resolvent in indolent tumours, and in sprains. Ratier. 16 122 BATHS, FOMENTATIONS, &C. Narcotic Fomentation. R. Gum Opii, gij. Aquae, Oj. Solve.—Adapted to painful affections of the joints, as chronic rheu- matism, Sic. Ratier. Narcotic Fomentation. R. Foliorum Dulcamara?, gij. Capsularum papaveris, gij. Aquae ferventis, Oj. Fiat infusum.—Employed as a soothing application to irritable sur- faces. Mustard Fomentation. R. Farina? sinapeos, giv. Aqua? ferventis, Oj. Misce.—By wetting cloths in this fluid and applying them to the skin, irritation may be prolonged to any requisite degree. Tobacco Fomentation. R. Foliorum tabaci, gij. Aqua? ferventis, Oj. Misce.—Employed in Psora, but is apt to produce nausea and vomit- ing. Fumigations are for the most part used to pu- rify infected air by absorbing or otherwise counter- acting deleterious gases. They are also employed in diseases of the skin, and may be sometimes substituted for a local bath. The ordinary process for fumigating apartments with chlorine, has been already described. (Page 86.) Fumigations of sulphur, cinnabar, and mercury are also in common use, for medicinal purposes, and are readily applied with a proper apparatus. For Inhalations, see Expectorants, p. 84. CAUSTICS, OR ESCHAROTICS. 123 CAUSTICS, OR ESCHAROTICS. Caustics or cauteries are divided into the actual and potential. The first consists of fire itself; and the second of those substances which destroy the living solids, either by excessive stimulation, or, as some have supposed, by producing a chemical decomposition. Common Caustic with Opium. R. Potassae cum Calce, gij. Pulveris Opii, gss. Saponis mollis, q. s. Misce.—This preparation is employed for the same purpose as the common caustic. Potassa. The Causticum commune acerrimum is the pure Potash: when mixed with lime, its activity is lessened, and it is then called Causticum commune mitius. For the best mode of applying this remedy, see the remarks on Issues. As this caustic spreads rapidly and eats deeply, care should be taken not to leave it on too long, when in the neighbourhood of large blood-vessels. When, however, we wish to arrest its effects, we may neutralize it at once by a little vinegar. Lunar Caustic. This caustic is the Nitras Argenti, deprived of its water of crystalliza- tion, fused and cast into moulds. Its mode of application is univer- sally known. It is free from the inconveniences of the former. Burnt Alum. The Alumen ustum is made by depriving this salt of its water of crystallization by heat. It is applied in powder to the fungous granulation of ulcers; and, mixed with an equal part of powdered sugar, is used to remove specks or nebulae of the cornea. 124 CAUSTICS, OR ESCHAROTICS. MINERAL ACIDS. The mineral acids are all escharotics, though seldom employed, because of the difficulty of managing fluids when used in this way. Nitric Acid diluted is some- times applied to extensive foul ulcers, in warm weather, to destroy the animalculse which are apt to be gene- rated in such sores. Solution of Muriate of Ammonia, $c. R. Muriatis Ammonia?, gj. Aceti destillati, 3ij. Aqua? fontanae, 3iv. Fiat solutio.—To be applied to venereal warts. Bell on Venereal. White Oxide of Arsenic, or Arsenious Acid. R. Acidi Arseniosi albi, 9j. Aqua? fontanae, 5ij. Fiat solutio. This solution is occasionally applied to cancerous sores : it was formerly used in the shape of powder or paste, as an empirical remedy. But it is now seldom employed, from the circumstance of its producing constitutional irritation. Sir Astley Cooper mentions cases where, from its aborption when applied to open sores, partial if not complete paralysis of the limbs was the consequence. Ointment of Arsenic. R. Acidi Arseniosi pulveris, gj. Adipis Suillae, Cerati cetacei, aa. gvj. Melt the cerate and lard over a slow fire, and then pour it on the white oxide of arsenic, and triturate it in a glass mortar until it is inti- mately united.—Pharm. Chirurg.—For cancers, &c. CAUSTICS, OR ESCHAROTICS. 125 The same care is required in its use as in the solu- tion. Dubois's Arsenical Powder. R. Oxydi arsenici albi, gss. Sulphureti Hydrargyri rubri, 3j. Resina? pterocarpi, gss. Fiatpulvis.—Chiefly used in the French hospitals as a caustic to can- cerous affections. Ratier. MOXA. This is another mode of using the actual cautery; and, as it is engaging the attention of physicians, we insert the usual mode of applying it.—The Chinese employ this remedy by means of the Mugwort. They separate this soft lanuginous substance by beating, and form it into a cone; the base of this is attached, by be- ing wetted, to the skin, and the point set on fire. Dr. Boyle recommends dipping cotton in a strong solution of nitrate of potash, and enclosing pieces of this thoroughly dried in paper cylinders, about one inch in diameter, and another inch in height. Dr. Burne employs wood in a state of dry-rot, touch-wood. This only requires to be shaped properly, and burns, he says, with certainty and steadiness, and is prefera- ble to the other modes suggested;—some of which, as common cotton, or lint, requiring the use of the bel- lows, and when they have been dipped in nitre, de- manding care to prevent the scintillations from injuring the surrounding parts. The cylinders or cones of touch-wood may be con- fined to the skin by a little adhesive plaster affixed to the edges. It is proposed to place pieces of cold iron in the neighbourhood of the part while the moxa is burning, in order to render the sensations more vague, and there- fore less painful. Moxa is used in diseases of the spine, paralysis, &c. &c. 126 STIMULATING OINTMENTS, &C. STIMULATING OINTMENTS, &c. Ointment of Red Precipitate. R. Hydrargyri oxydi rubri, 3j. Terebinthinae venetae, gj. Fiat unguentum. This preparation may be applied to indolent sores, and is said, by some practitioners, to be a specific in itch. White Precipitate. R. Hydrargyri precipitati albi, gr. xv. Nitratis Potassae, gss. Florum Sulphuris, gj. Bene teranturet adde— Axungiae Porcinae, 3ij. Fiat unguentum. Dr. Chapman remarks, that this ointment has long been celebrated in the cure of itch. Solution of Phosphoric Acid. R. Acidi phosphorici, gj. Aqua? destillatae, gviij. Fiat solutio. Dr. Lentin, a German Physician, has employed this solution on compresses applied to ulcers situated over carious bones, and he imagines with decided benefit.— Spillaris Supplement to the British Pharmacopoeias. Corrosive Sublimate and Lime-Water. R. Chloridi Hydrargyri corrosivi, gr. j vel iij. Aqua? Calcis, gj. Fiat solutio.—Signa.—The yellow wash. STIMULATING OINTMENTS, &,C. 127 For ordinary purposes one grain to the ounce will be sufficient. It is employed in phagedenic and vene- real ulcers. Calomel and Lime-Water. R. Hydrargyri Chloridi mitis, 3J. Aquae Calcis, giv. Misce.—Signa.—The black wash. This prescription is used in the same cases as the other. The red-oxide in that, and the black-oxide of mercury in this, are precipitated by the lime-water. They are sometimes administered in the form of in- jections, in gleets and obstinate gonorrhoea. Anli-psoric Ijotion of Dupuytren. R. Sulphureti potassae, giv. Aquae, Oj. Acidi sulphurici, giv. Misce.—To be applied two or three times a-day on the parts covered with pustules, and with this treatment the simple bath is conjoined. Lotion of Myrrh. R. Tincturae Myrrhae, Liquoris Calci, aa. gj. Misce. This lotion is recommended by Dr. Kirkland for taking down fungous flesh. In cases of fungous brain, he found it extremely serviceable applied to the excre- scence on dossils of lint. Powder of Verdigris and Calomel. R. Acetatis Cupri, Hydrargyri chloridi mitis, aa. 9j. Fiat pulvis subtillisimus.—For chancres and indolent ulcere, 128 ISSUES AND SETONS. Powdered Rhubarb, $-c. R. Pulveris Rhei, ------ Ipacacuanhae, aa. gj. Fiat pulvis.—To be dusted on sarcomatous and warty tumours. Rhubarb alone forms an excellent application to in- dolent ulcers. Powder of Savin, &/c. R. Pulveris Sabina?, ------ Acetatis Cupri, aa. 3j. Fiat pulvis.—To be dusted on sores accompanied with fungus ex- crescences. Ointment with Carbonate of Ammonia, fyc. R. Carbonatis Ammoniae, 3ss. Unguenti simplicis, 3ss. Fiat unguentum.—To be used in indolent ulcers of a scrofulous cha- racter. ISSUES AND SETONS. These remedies are employed as substitutes for blis- ters, where a permanent discharge is desired. We therefore insert the best rules for their employ- ment. There are three kinds of issues in common use, by either of which we may procure a discharge of puru- lent matter for any length of time that may be re- quired. They are applied in different situations, ac- cording to circumstances, and some one of the following parts is generally chosen; the nape of the neck; the hollow of the deltoid muscle, and between the shoul- ders or ribs; in the inferior extremities they are most conveniently formed in the inside of the leg, either above or below the knee. ISSUES AND SETONS. 120 1. Blister Issue. To form this issue it is merely necessary to apply a blister to any part in the usual manner; the skin being thus removed, the discharge should be continued by means of stimulating ointments, as Unguen- tum Cantharidum, Ung. Basilici, Ung. Sabinae, etc. These may be alternated with mild liniments, in order to prevent the ulceration and consequent discharge from becoming excessive. 2. The Pea Issue. There are two modes of forming this issue; the first is made by means of a lancet; the part is merely taken in the thumb and finger, and an incision made by passing the lancet through the skin. The wound should be kept open by means of orange peas, the common pea, a bean, or a bit of orris root. The following extracts from the Surgeon's Vade Mecum, will best exemplify the manner of forming the issue with caustic:— " The part is first to be covered with a piece of ad- hesive plaster, in the centre of which a circular hole has been cut of the size of the intended issue; in this hole the caustic, kali purum, made into a paste with soap, is to be placed. The whole is then to be covered with another plaster, secured by a bandage, and suf- fered to remain for ten or twelve hours. Generally in two or three days an eschar begins to separate, when the opening should be filled with the substance made choice of." These substances are enumerated above. 3. TheSeton. To form this artificial discharge, take the seton needle, to which is attached a skein of silk, the latter being partially anointed with some oleaginous substance. The needle is to be passed completely through the part chosen for the operation, after which it is removed, and the ends of the silk left hanging from the wound. It should be dressed every day, or twice a-day, with some mild ointment; and if this be not sufficient to keep up the discharge, the more stimulating unguents may be used, as mentioned when speaking of the blister issue. 17 130 BOUGIES. BOUGIES. Although directions for forming bougies may appear out of place under this head, yet as country physicians may often be obliged to make these articles, we can not forbear inserting the formula?, and we see no more appropriate place in the work. R. Cera? alba?, gxvj. Terebinthinae venetae, 3iss. Olei olivarum, gi. Melt the wax and turpentine over a slow fire, and then add the oil. Bougie, with Red Lead. R. Olivarum Olei, Oj. Cera? flavae, gx. Oxidi Plumbi rubri, gxv. Boil over a slow fire until the minium is perfectly dissolved, which will be in about four or six hours. Dr. Swediaur's Bougie. R. Cera? flavae, Jfcj. Cetacei ceti, 3iij- Plumbi acetatis, 3 v. These are to be boiled like the former until the composition is of a proper consistence for forming bougies. Sharp's Bougie. R. Diachyli cum pice Burgundica, gij. Argenti vivi, gj. Antimonii sulphureti ppt: gss. The quicksilver to be previously dissolved in balsam of sulphur or in honey, and added to the plaster when melted in a moderate heat. Bell on Venereal. In order to form a bougie, a slip of linen, an inch in width at one end, and an inch and a quarter at the other, and from ten to twelve inches long, must be dipped into the melted composition, taking care that it be evenly applied; it is then to be carefully folded up BOUGIES. 131 into the proper longitudinal shape, and rolled firmly between two marble slabs, till perfectly smooth and even.—Pharmacop. Chirurgica. The caustic bougie is made by simply rolling in the centre of the wax bougie, at the extremity, a small piece of lunar or common caustic. The former is more manageable, and therefore generally preferred. Bougies are sometimes dipped in Basilicon or mercurial oint- ment, oil of turpentine, &c, in order to render them more stimulating when employed in the treatment of gleet, &c. ( 132 ) CLASS X. STIMULANTS. In the use of stimulants, it is for the most part ad- visable to begin with small doses, and augment them as circumstances may require. There are cases, how- ever, in which it is necessary to give them plentifully ab initio. It will be often requisite to change not only the sti- mulating substances, but the part of the body to which they are applied; thus when the stomach fails, the rectum and skin may be acted upon with advantage. PILLS, POWDERS, &c. Pills of Camphor, fyc. R. Pulveris Lyttae, gr. xviij. -------Opii, -------Camphorae, aa. gr. xxxvj. Conservae rosarum, q. s. Ut fiant pilulae xxxvj.—Of which one or two may be taken every night on going to bed. Designed for impotency arising from general debi- lity. Pills of Deuto-iodide of Mercury. R. Deuto-iodidi Hydrargyri, gr. j. Extracti Juniperis vel Glycyrrhiza?, gr. xij. STIMULANTS. 133 Divide in pilulas viij.—Signa.—Two in the morning and two at night; dose to be augmented gradually to four in the morning and four at night. Pills of proto-iodide of mercury may be made in the same proportions and given in the same doses. In scrofula. Pills of Turpentine, fyc. R. Pulveris Guaiaci, gj. Terebinthinae venetae, q. s. Ut fiant pilula? xv.—Signa.—One three times a-day. These pills have a powerful effect upon the urinary organs. They are employed in gleet and leucorrhcea, and frequently produce the most obstinate strangury. Pills of Cayenne Pepper. R. Pulveris Capsici,gj. Mica? panis, Aquae destillatae, aa. q. s. Ut fiant pilulae xij.—Signa.—One three or four times a-day. In de- bility of the stomach, resulting from intemperance. Aromatic Pills. R. Carbonatis Ammonia?, Capsici, Caryophylii, Macis, aa. ^j. Olei Carui, gtt. v. Extracti Gentiana?, gr. xij. Syrupi simplicis, q. s. Ut fiant pilulae xx.—Signa.—One every two hours in gout of the sto- mach. Dr. Parrisk. Tincture of Cantharades, <$'c. R. Radicis Rhei contusae giss. Guaiaci, gr. xlv. Gummi Laccae, 3ss. Cantharidum contusarum, 3J. Spiritus vini rectificati, gxij. 134 STIMULANTS. Fiat infusio, et cola. Dose from thirty to fifty drops, night and morn- ing, in a draught of water. In gleets. From the active nature of these articles, we would recommend caution in the use of them. Mixture of Carbonate of Ammonia, $c. R. Carbonatis Ammoniae, 3iss. Pulveris sacchari albi, ------ gummi Acacia?, aa. ^iss. Spiritus Lavendula? compositi, 3ij- Aquae destillatae, vel Mentha?, riv. Fiat mistura.—Signa.—A table-spoonful for a dose, every one or two hours.—And, if desirable, Tinct. Opii, gtt. xl vel 1. may be added to the mixture. Draught with Valerian and Carbonate of Ammonia. R. Pulveris Valeriana?, 9j. Carbonatis Ammonia?, gr. xv. Aqua? Cinnamomi, gij. Misce.—Fiat haustus.—To be taken every fourth hour. Suited to cases of nervous headach, and depression of spirits. Mixture of Cubebs, fyc. R. Pulveris Cubebarum, ^ij. Carbonatis Sodae, gss. Mucilaginis Acacia?, gvj. Aquae Menthae, gvj. Fiat mistura.—Signa.—Take a table-spoonful every hour and a-half. Mixture of Oxide of Bismuth, Cubebs, fyc. R. Pulveris Cubebarum, 3ij- Sub-nitratis Bismuthi, 3ss. Mucilaginis Acacia?, gss. :; Syrupi simplicis, gvj. Aquae destillatae, gvj. Fiat mistura.—Signa.—Take two table-spoonsful three times a-day. STIMULANTS. 135 We have extracted these prescriptions from a paper of John Fosbroke, surgeon, Chittenham; published in the Medical Recorder, April, 1825. They are recommended, with other similar com- pounds, in various affections of the mucous mem- branes :—viz. of the bowels, bladder, trachea, &c. There is not much general confidence reposed in cubebs in this country. Perhaps this skepticism as to their efficacy may not be well founded. Camphorated Enema. R, Enematis communis, f^ij. Camphorae, ^ij. Vitellum unius ovi. Misce.—Signa.—One fourth part to be thrown up the rectum in the treatment of putrid fevers, pro renata. M. Chaussier. R. Acetatis Ammoniae.—Quantum placet. This article,it is said, will dissipate inebriety in less than five minutes. The dose may be safely ten grains. Antisceptic Pills. R. Camphorae, Nitratis potassae, Pulveris Gummi Arabicae, aa. 9j. Mix, and divide into pills of four grains each.—Dose two pills every hour or two hours, when a tendency to gangrene exists. Draught with Powdered Ginger, fyc. R. Pulveris Zingiberis, gr. xv. Carbonatis Ammonia?, gr. viij. Spiritus Cinnamomi, gij. Aqua?, giss. Misce.—Signa.—To be taken at once. In cases of gout in the sto- mach. 136 STIMULANTS. Camphor Mixture. R. Camphorae, ^j. Pulveris gummi Arabici, ------- Sacchari albi, aa. giss. Tinctura? Opii, gtt. xl. Aqua? Mentha?, giv. Fiat mistura.—Signa.—A table-spoonful to be given every two hours. In reducing camphor to powder, (which must be done before it can be formed into a mixture,) it is ne- cessary to add to it a few drops of alcohol. Camphor in Milk. R. Camphorae, gj. Lactis bullientis, giv. Fiat solutio.—This preparation may be taken in the manner as di- rected in the former. Camphor Julep. R. Camphorae, 3j. Aquae bullientis, ^viij. Fiat mistura.—This preparation should be set aside in a covered ves- sel for half an hour, and then strained.—Signa.—A table-spoonful for a dose pro re nata. Camphor with Magnesia. R. Camphorae pulverizatae, gj. Magnesiae carbonatis, gij. Aquae destillatae, Oj. Fiat mistura. This prescription answers the same purpose as the former. It is considered a more elegant preparation, and is given in the same doses. It should be suffered to settle; and the clear liquor, which is slightly impreg- nated with the camphor, decanted for use. STIMULANTS. 137 Camphor with Myrrh. R. Camphorae pulverizatae, gj. Pulveris gummi Myrrhae, 2ss. ------ Sacchari albi, gij. Aquae destillatae, 3vj Misce.—Signa.—A table-spoonful to be given every two hours. Mixture with Oil of Turpentine. R. Olei Terebinthinae, gtt. cxx. Pulveris gummi Arabici, ------ Sacchari albi, aa. gij. Tincturae Opii, gtt. lx. -------Lavendulae compositae, 3ij- Aquae Menthae sativae, 3v. Fiat mistura.—Signa.—A table-spoonful for a dose every two hours. This remedy has gained great reputation in some of the low forms of fever. The author once employed it in the dose prescribed above, in passive hemorrhage from the bowels, with complete success; and in he- morrhage from the bladder, resulting from low fever, he knows it to have been given with equal advantage. Linctus with Oil of Turpentine. R. Olei Terebinthinae, 3ij. Mellis optimi, 5j. Fiat linctus—Dose a tea-spoonful night and morning, with a draught of warm tea. In Sciatica. Emulsion of Phosphorus. R. Phosphori puri, gr. ij. Mucilaginis Arabici, q. s. Let these articles be carefully and effectually triturated in a mortar, and add gradually as much distilled water as will make an emulsion of gvj. then add— Syrupi simplicis, ?j. Liquoris Hoffmani mineralis, gtt. xxx. Fiat mistura.—Of which the usual dose is a table-spoonful every two hour.^. IS 138 STIMULANTS. This preparation was originally made by the cele- brated Hufeland, and is now taken from Dr. Chap- man's Therapeutics, p. 176, vol. 2. The violence of the remedy, and its very great power, are generally known to physicians. We need hardly repeat the necessity there is for the greatest caution in its administration. It is sometimes given in sweet oil, but this is said to be extremely nauseous. A saturated solution of ether has also been employed, and is perhaps as neat a mode as any other. This solution contains about eight grains to the ounce. Mixture of Camphor and Guaiacum. R. Tincturae Opii Camphoratae, ------ Guaiaci ammoniatae, aa. ?j. Fiat mistura, et signa.—Two tea-spoonsful every two hours. In misplaced and retrocedent gout. Aromatic Spirit of Hartshorn. R. Spiritus Ammonia? aromatici, rij. Signa.—Twenty drops to be given in half a wine-glassful of water, pro re nata. In sudden exhaustion from any cause. Mustard Seed. R. Seminum Sinapeos albi, ?j. Signa—A tea-spoonful of the unbruised seeds two or three times a-day. They are said to prove beneficial in costive habits, where the con- stipation depends upon a torpid state of the muscular coat of the intestines.—Paris on Diet, p. 187. Infusion of Sassafras, &;c. R. Corticis Sassafragis, ?ss. Radicis Glycyrrhizae, 3ij. Aqua? bullientis, Oj. Fiat infusio.—Signa.-One half may be taken in the morning, and the other half in the evenino-. Recommended highly by the Germans in many diseases of a scrofulous character.—Hufeland1 s Trea- tise. STIMULANTS. 139 Mustard Whey. R. Lactis vaccinae, ffoj. Seminum Sinapeos contus: 5j. Simmer until the caseous part separates, then strain, and add— Vini albi, 5vj. Signa.—A draught of this whey may be taken every hour or two in low fever, and debilitated stomach. Wine Wliey. R. Lactis vaccinae, Oss. Vini albi, (Madeira,) ?j vel ?ij. Boil the milk and then add the wine. There are few mild stimulants more employed, or more useful than wine whey. Dr. Chapman speaks of it as having particularly a kindred action with car- bonate of ammonia. The dose to be regulated by the circumstances of the case; from four ounces to ten during the day. Infusion of Cayenne Pepper. R. Pulveris Capsici annui, giss. Aquae bullientis, Oss. Fiat infusio.—Signa.—A table-spoonful for a dose in severe colic, or gout in the stomach. For the external use of it, see Rubefacients. Infusion of Cloves. R. Caryophylli contusi, 3j- Aquae bullientis, Oss. Fiat infusio.—Signa.—To be employed in the same cases, and in similar doses as the former. This preparation is also very useful as an adjunct to bark in intermittent fever. An Infusion of Ginger, Is also an excellent stomachic, and may be employed with great benefit in debility of the stomach and bowels. 140 STIMULANTS. Mixture with Wine, $-c. R. VitellumOvij. Olei Cinnamomi, gtt. xx. Misce, et adde— Vini albi, (Madeira,) Aqua? Cinnamomi, aa. 3iij. ---- destillatae, 3ij. Sacchari albi, 3ij- Signa.—Three spoonsful for a dose. During convalescence from low fevers. ( 141 ) CLASS XI. NARCOTICS. Narcotics have been denominated Sedatives, from their power of diminishing action; Anodynes, from their capability of alleviating pain; and Hypnotics, or Soporifics, from their power of inducing sleep. A few words only will be necessary as general rules for their administration, and any peculiarities that individuals of the class may possess will be noticed under the ap- propriate prescriptions. It is well known they possess the power of fulfilling two indications; namely, of ex- citing and depressing the powers of the system. To obtain the first of these results, it is necessary to begin with small doses, and repeat them frequently; while, in order to arrive at the second, a full dose must be given, and not resorted to again for a considerable length of time. We should also bear in mind that the system very soon becomes habituated to their action, and the doses must be continually enlarged if it be found necessary to maintain their impression. The difference between the susceptibility to their action when the body is in a morbid or healthy condition, should not be forgotten. PILLS. R. Pulveris Opii, gr. xij. Saponis albi, gr. iij. Misce et divide in pilulas, xij.—Of which one is the ordinary dose to produce sleep. 142 NARCOTICS. In equal weights of powdered and soft opium, the former is much the more powerful, the latter contain- ing a considerable proportion of water. This should be recollected when we are directing them in the form of pills. An opium pill that has been made long enough to become perfectly* hard and dry, will be retained by an irritable stomach when a fresh one would be rejected. Pills of Lupulin. R. Lupulina? purae, gss. Contunde in mortario, et divide in pilulas x. Signa.—From two to four pills may be given for a dose. This substance, we are told by Dr. Ives, contains all the active properties of the hop. It is slightly narcotic, and will prove serviceable in irritable states of the stomach. The lupulin may be administered in powder, with two parts of white sugar, if it be deemed a preferable mode. Pills of Acetate of Morphia. R. Acetatis morphia?, gr. iij. Conservae rosarum, q. s., ut fiant pilula?, xij. Signa.—One may be given for a dose, repeated pro re nata. One grain of either of the salts of morphia, is usually estimated as equal to four of opium. The Sulphate and Muriate of Morphia are prepared in the same way, and given in the same dose. Pills of Lactucarium. R. Lactucarii optimi, gr. xij. Divide in pilulas, vj. Signa.—One for a dose, to be repeated in two hours, if sleep be not procured. NARCOTICS. 143 The inspissated juice of the garden lettuce is said to act as a direct sedative, lessening the frequency of the pulse, diminishing the natural heat, and procuring sleep, without inducing the subsequent distressing effects which follow the use of opium. The Thridace of the French appears to be prepared by a different process from that employed in the pre- paration of the British Lactucarium. The former is not so highly esteemed in this country as the latter. Pills of Hyosciamus and Ipecacuanha. R. Extracti Hyosciami nigri, gr. x. Pulveris Ipecacuanha?, gr. v. Misce et divide in pilulas x.—Signa.—One every half hour until re- lief is procured. These pills are recommended by Dr. Paris, in his work on diet, in cases of flatulence. They are de- signed to calm the irritability of the bowels. Pills of Opium, Hyosciamus, fyc. R. Pulveris Opii, gr. iv. Extracti Hyosciami, -------Conii, aa. gr. xv. Fiat massa in pilulas vj. dividenda.—One every night where an ano- dyne is required. Pills of Extract of Hyosciamus. R. Extracti Hyosciami nigri, 9j. Divide in pilulas x.—Of which one may be given every four hours, increasing the dose as required. This medicine is employed as a substitute for opium, and is said not to constipate the bowels. Pills of Extract of Stramonium. R. Extracti Stramonii, gss. Divide in pilulas xv.—Signa.—One three times a-day. 144 NARCOTICS. The powdered leaves and seeds are also employed in similar doses. Vide Expectorants. Opiate Confection, R. Confectionis Opii, gss. To be given for a dose.—One grain of opium is contained in forty- three grains of the Edinburgh confection. Pills of Extract of Conium. R. Extracti Conii, gj. Pulveris foliorum Conii, q. s.; ut fiat massa, et in pilulas xx divi- denda. One of these pills night and morning, may be taken at the commence- ment, gradually increasing them to two, three, four, or more, as the patient can bear them. The efficacy of narcotic plants is influenced by soil, climate, exposure, and cultivation; and the extracts by the season when the plants are gathered, and the mode of preparing them. Physicians would do well there- fore to make themselves acquainted with the quality of the article they prescribe, inasmuch as there may be a fatal difference between two parcels of different ages, modes of preparation, &c.— Vide Journal of the Phila- delphia College of Pharmacy.—On Narcotic Extracts, Vol. II. Pills of Camphor. R. Gummi camphorae, 3ss. Gummi Arabici, Alcoholis, aa. q. s. Ut fiant pilulae xv.—Dose.—A pill every two or three hours. Pills of Opium, Digitalis, &/c. R. Pulveris Opii, --------Digitalis, aa. gr. vj. Conserva? rosarum, q. s., ut fiant pilulae xij. Signa.—One to be taken every four hours. In Asthma, &c. NARCOTJCS. 145 Pills of Extract of Conium and Calomel. R. Extracti Conii, 9ij. Hydrargyri chloridi mitis, gr. xv. Misce.—Fiant pilula? xv.—Signa.—One three times a-day. In pseu- do-syphilitic affections. Pills of Powdered Nux Vomica. R. Pulveris Nucis vomicae, 3ss. Conservae rosarum, q. s., ut fiant pilulae x. Signa.—One to be given two or three times a-day, closely watching the effects. In paralysis. Pills of the Resin of Nux Vomica. R. Extracti Nucis vomicae resinosi, gr. x. Divide in pilulas xv.—One pill twice a-day, gradually augmenting until tetanic effects are produced. Pills of Strychnia. R. Strychnia?, gr. ij. Conserva? rosarum, q. s., ut fiant pilula? xxiv. Of which one pill may be given once or twice a-day, according to the idiosyncrasy of the patient. This latter medicine is still more powerful than the former two: for their mode of preparation, manner of exhibition, and peculiar effects, see Majendie's Formu- lary, page 82. It is only necessary in this place to observe, that great nicety is requisite in dividing the mass into pills of equal strength. Tincture of Strychnia. R. Alcohol, 3j. Strychnia?, gr. iij. Fiat tinctura.—This tincture to be given by drops, from six to twenty- four, in draughts or drinks. 19 146 NARCOTICS. Draught of Strychnia. R. Strychnia? puree, gr. j. Sacchari albi, gij. Acidi acetici, gtt. ij. Aqua? destillatae, gij. Fiat solutio.—Signa.—A tea-spoonful morning and evening. Strychnia forms with acids a variety of salts, which generally are very soluble, and for this reason much more active than the alkali uncombined. These may be resorted to when the system becomes habituated to the action of strychnia. The commencing dose of the salts, should not be greater than that of the alkaloid. It should be borne in mind that this substance will be increased by all acid drinks, such as lemonade, both in solubility and power.—See Majendie's Formulary, Edit. 5, p. 12. MIXTURES, TINCTURES, Sic. Opiate Mixture. R. Pulveris Opii, 9ss. Sacchari albi, 3J- Aquae Cinnamomi, 5vj. Fiat mistura.—Signa.—A table-spoonful may be taken every two hours, so that the whole be consumed in twenty-four. In cases of tetanus and colica pictonum. Hemlock Mixture. R. Succi Conii spissati, 3ss. Syrupi Papaveris albi, ^j. Aquae destillatae, gvij. Misce.—A table-spoonful three or four times a-day for a dose. Tincture of Resin of Nux Vomica. R. Extracti Nucis vomicae exsiccati, gr. iij. Spiritus vini rectificati, gj. Fiat tinctura.—This tincture to be given in doses of fifteen or twenty drops, in any kind of drink. NARCOTICS. 147 This preparation, and the pills made of the resin of nux vomica, have been successfully used in cases of general and local paralysis. Nux vomica is also ap- plied by friction in paralytic and other nervous diseases. The following is Majendie's formula for this purpose: R. Tincturae nucis vomicae, ?j. Aquae Ammoniae (ammoniaque concentree,) 3ij- Misce.— Opiate Collyrium, R. Pulveris Opii, gr. j. Camphora?\ gr. v. Mucilaginis Acacia?, ?j. Misce, et fiat collyrium. Anodyne Draught. R. Tinctura? Opii, gtt. xv vel xxv. Syrupi Papaveris, 3ij- Spiritus Cinnamomi, 3j. Aqua? destillatae, gise. Misce.—Signa.—Anodyne draught. Laudanum is very disagreeable to some persons; combined as above, the taste may be disguised. As the regulation of doses for children is, to the young practitioner, one of the most difficult parts of prescribing; and as laudanum is an article so uni- versally employed in their diseases, we subjoin the following graduated table from Dr. Dorsey's Syllabus, 1817, page 36. For a child at birth, or within a month after I to 1 drop. Under a year old - - - - 5 to 2 or 3 From one to two years of age - - - 1 to 5 From two to five.....2 to 8 From five to ten.....5 to 15 From ten to fifteen.....10 to 20 At fifteen years.....15 to 20 For an adult - - - - - 25 to 30 145 NARCOTICS. It is important in the employment of this remedy, that it should be a saturated tincture, and perfectly transparent. For these reasons it should be obtained from the apothecary in small quantities, as it is liable to deposite part of the opium; hence the liquid near the surface is weaker, and causes that in the bottom of the phial to be very strong, if it be shaken before using. Infants have been destroyed by the exhibition of thick laudanum. Physicians, therefore, should always ex- amine the phial, if any be in the possession of a family, before trusting the nurse to give a dose to the child. Solution of Acetate of Morphia. R. Acetatis Morphia?, gr. xvj. Aqua? destillatae, gvj. Acidi acetici diluti, gij. Misce.—The dose is from ten to twenty drops. Sirup of Acetate of Morphia. R. Acetatis Morphia?, gr, iv. Syrupi simplicis, ffcj. Misce.—Signa.—Two tea-spoonsful may be taken for a dose, and repeated pro re nala. The sirup of the sulphate of morphia may be made in the same proportions, and given in the same doses. The latter salt has one superiority over the former, namely, that the acetate when dissolved in water is decomposed, two salts resulting, the one soluble, the other not. From this objection the sulphate is ex- empt. Majendie states that, by alternating these new alka- line remedies, we may prolong the effect without in- creasing the dose. If this observation be correct it is well worth remembering.—Majendie's Formulary, Solution of Sulphate of Morphia. R. Morphia? sulphatis, gr. ij. Aqua? destillatae, gij. NARCOTICS. 149 Fiat solutio.—Dose.—A tea-spoonful, repeated according to circum- stances. Twice that quantity is nearly equivalent to a grain of opium or twenty-five or thirty drops of laudanum. The muriate and nitrate of morphia possess no ad- vantages over the sulphate and acetate. Solution of Cilale of Morphia. R. Morphinae puree, gr. xvj. Acidi citrici crystallizati, gr. viij. Aqua? destillatae, gj. Tincturae coccinellae, q. s. Ut fiat solutio.—Dose five to twenty drops, pro re nala. Majendie. The French chemists have also discovered in opium a principle allied in its effects to morphia, and called Codeine. In dose of a single grain it proves highly anodyne, but distresses the stomach in larger doses. Its salts are given in somewhat smaller quantities.— Majendie, 9vme, Ed. p. 80. A preparation of opium, known as McMunris Elixir, has been for several years much in vogue in this coun- try. The mode of preparation is a secret with the proprietor; but the medicine has certainly some ad- vantages over all others of its class. For example, it rarely affects the head, and causes little or no constipa- tion, but acts freely on the urinary organs and skin. It is given in the same dose as laudanum. Tincture of Lupulin. R. Lupulina? purae contusae, gj. Alcohol, gij. Digest for six days in a close vessel. Strain, filter, and add a suffi- cient quantity of alcohol to make 5iij. of the tincture. Of this from 3ss. to 3ij. may be taken for a dose.—See Pharmacologic, art. Humulus. Tincture of Hops. R. Tincturae Lupulorum, gj. Signa.—Of this, a tea-spoonful may be taken as a narcotic in cases where opium is inadmissible. 150 NARCOTICS. Hops are also given in the form of infusion; for which see tonics. Enclosed in a bag, they have ac- quired some celebrity as a pillow. Their soporific powers, however, when thus employed, are very equivocal. Camphor and Hoffman's Anodyne. R. Aquae camphorae, giv. Liquor Hoffmanni, gij. Misce.—Dose.—A dessert-spoonful every hour or two hours. In nervous affections, and the sleeplessness of fever. Infusion of Camphor. R. Camphorae gummi, gj. Aquae bullientis, gviij. Pour the hot water on the gum, and allow it to stand until cold: it should be then kept in a well-stopped phial. Dose.—A table- spoonful every hour or two hours. In febrile pervigilium and nervous irritability. Tincture of Opium and Oil of Turpentine. R. Tinctura? Opii, ^j. Olei Terebinthinae, ^ss. Misce.—Signa.—A tea-spoonful every hour, may be given in delirium tremens. The turpentine may be added or omitted at the dis- cretion of the physician, and the quantity of laudanum in some cases may be doubled. We have given two tea-spoonsful every hour until |ij. of laudanum were taken, with success. We do not believe in the doc- trine, however, that opium in this disease may be administered almost ad libitum without danger. On the contrary, we are well assured that death has been caused by the excessive use of this narcotic in delirium tremens. Denarcotized Laudanum. R. Tinctura? Opii sine Narcotina. VARCOTICS. 151 This preparation, now common in all our shops, was proposed by Robiquet. It is said to relieve pain and induce sleep, without producing the ordinary sequel© of opium or laudanum. Black Drop. R. Tinctura? Opii acetata?, 3i- From six to eight drops of this preparation may be given to an adult for a dose. It is said to be three times the strength of laudanum, but has obtained celebrity from the fact, that it equally promotes the ends of laudanum without affecting the head and stomach. Where it cannot be had, it is stated by Dr. Chapman, that by giving the alcoholic tincture of opium in vinegar, we obtain nearly the same results. Elixir Paregoric. R. Tincturae Opii camphoratae. A tea-spoonful of this may be given to an adult for a dose. It is prin- cipally employed as an expectorant. Wine of Opium. The dose of the Vinum Opii is the same as the spirituous tincture; though we believe it is seldom employed, except as an external ap- plication to chronic inflammation of the eyes. Tincture of Digitalis. R. Tincturae Digitalis,gij. Of which ten drops may be given at first twice or three times a-day, increasing the quantity as the system becomes accustomed to it. The peculiar character of this remedy should induce caution in giving it. For its particular applications and effects, see Ex- pectorants and Diuretics. Infusion and Tincture of Digitalis. Vide Diuretics and Expectorants, 152 NARCOTICS. Infusion of Conium. R. Foliorum Conii, 3ss. Aquae bullientis, Oj. Fiat infusio et cola.—Signa.—To be applied as a wash to' cancerous and scirrhous ulcers. A cataplasm is also employed for the same purpose, made by mixing the powdered leaves with bread and water poultice. Solution of the Extract of Belladonna. R. Extracti Belladonnae, 9j. Aquae destillatae, 3iij- Fiat solutio.—Signa.—To be applied to the eye in cases of cataract, for the purpose of dilating the pupil and exposing the lens. The extract of belladonna is occasionally given in doses of a grain three or four times a-day. Ointment of Belladonna. R. Extracti Belladonna?, 3ij- Aquae destillatae, 3ij< Adipis suilli, 3ij. Fiat unguentum.—To be applied to the neck of the uterus in rigidity of that part, occasioned by disease, or previous to delivery. It is said to act on the same principle as it does in dilating the iris. The application to be made for some time by means of a syringe with a wide mouth. M. Chaussier. Infusion of Hyosciamus Niger. R Foliorum Hyosciami nigri, ^ss. Aquae bullientis, Oj. Fiat infusio.—Employed as an external application to cancerous, scro- fulous, and other indolent ulcers. Decoction of Bitter Sweet. R. Dulcamara? stipitum, gj. Aquae destillatae, Ojss. Boil to a pint and strain. NARCOTICS. 153 Dr. Chapman directs a wine-glassful to be taken fre- quently, and gradually increased, until a pint is con- sumed daily, in chronic eruptions, &c. The same preparation is employed as a wash. Decoction of Stramonium in Milk. R. Foliorum Stramonii, 3ij- Lactis recentis, Oiss. Boil to a pint and strain. Apply to gouty, rheumatic, and other pain- ful swellings. Solution of Extract of Belladonna. R. Extracti Belladonna?, gr. iij. Aqua? Cinnamomi, gj. Fiat solutio.—Signa.—Two or three drops twice or thrice a-day, to a child under a year old, and an additional drop for every additional year. Belladonna has been recently used in Germany as a preventive of scarlatina. The extract, if given for se- veral days, produces a scarlet eruption, and affection of the fauces, analogous to those of scarlatina; and it is pretended that this factitious disease is sufficient to prevent the access of the real one. Opium Enema. R. Pulveris Opii, gr. ij. Mucilaginis Acacia?, 5ss. Lactis tepifacti, gij. Misce pro enemate. Opium Enema. R. Pulveris Opii, gr. iij vel iv. Axungiae Porcinae, gj. Melt them together with a gentle heat, and when of a proper warmth, inject the mixture with a small syringe. 20 154 NARCOTICS. Solution of Opium in Lime Water, &;c. R. Extracti Opii, gr. j. Aquae Calcis, Olei Amygdalae dulcis, aa. 3iij. Fiat mistura.—Recommended by Dr. Sibergundi of Dorsten, in the treatment of sore nipples. It is to be applied to the parts on dossils of lint. Laudanum Enema. R. Tincturae Thebaicae, gj. Infusionis Lini, 3ij« Fiat enema. It is generally observed that three times the quantity of a remedy may be thrown into the rectum that may be taken into the stomach. As regards opium, how- ever, we believe it to be too much, particularly in chil- dren. Indeed, it is an unsettled point in therapeutics, whether remedies act most powerfully upon the rectum or the stomach. Suppository of Opium. R. Pulveris Opii, gr. ij. Saponis albi, gr. iv. Misce bene.—Introduce into the rectum, when an enema cannot be administered. Plaster of Opium, fyc. R. Opii puri, Camphorae, aa.. 3ss. Emplastri Lithargyri, 3u« Melt the plaster, and having previously powdered the other articles, mix them gradually, stirring it. For local pains. Plaster of Opium. R. Pulveris Opii, --------Camphorae, --------Saponis albi, aa. gj. Tinctura? Thebaicae, q. s.—ut fiat emplastrum. NARCOTICS. 155 This plaster is recommended by Dr. Dewees, and is employed in the same case as the above. Another, and the most common plan, is to spread Theriaca Andromachi* on leather of the size required, and cover it with powdered opium, sprinkling a. little laudanum to promote the adhesion of the opium. * The original Theriaca Andromachi is composed of sixty-one ingredients, pulverized and rubbed up with honey into an electuary. A preparation bearing the same name, but used for the same purposes, is now made in a much less elaborate way. The word Theriaca is, at the present day, applied to any coarse sirup, as treacle or molasses. ( 15fi ) CLASS XII. ANTISPASMODICS. Antispasmodics are those medicines which allay spasm, and compose the irregular actions of the nervous system. Some of the most powerful of them are de- rived from the class of Narcotics. Pills of Asafoetida and Soap. R. Gummi Asafcetidae, gj Saponis albi, gr. x. Aquae fontis, q. s., ut fiant pilulae xx. Two or four of these pills may be taken for a dose and repeated pro re nata. Pilula? Asafcetidae cum aloe, et ---------------cum Rheo, May be given in the same doses as those made with soap only. Opium Pills. As under Narcotics. Pills with Castor and Salt of Amber. R. Castorei, 3j. Acidi Succinici, gss. Extracti Gentians?, q. s., ut fiant pilula? xxiv. Dose three pills night and morning.—In hysteria. antispasmodics. 157 Calomel Pills. As under Sialagogues. Pills of Musk, Camphor, fyc. R. Moschi optimi, 9ss. Camphorae, 9j. Gummi Ammoniaci, 9ij. Opii purificati, gr. iv. Misce, et fiant pilulae singulae, gr. iv. Signa.—The dose may be four or five in the twenty-four hours. In nervous diseases. M. A. Richard. Bolus with Valerian and Rust of Iron. R. Pulveris radicis Valerianae, gj. Carbonatis praecipitatis Ferri, 9ss. Mucilaginis Acacia?, q. s., ut fiat bolus. One three times a-day. Bolus with Musk and Camphor. R. Camphorae, gr. v. Moschi, gr. xv. Syrupi simplicis, q. s., ut fiat bolus. Signa.—To be taken at once. This is a strong dose, but can be readily modified by the practitioner. To confine the aroma, musk should always be kept in phials, whether in the form of pills or otherwise. Bolus with Musk and Carbonate of Ammonia. R. Moschi, Carbonatis Ammoniae, aa. 9ss. Conserva? rosarum, q. s., ut fiat bolus. To be taken every third hour. Recommended in mortification accompanied with spasmodic action. 158 antispasmodics. Musk Mixture. R. Moschi optimi, 3ij- Sacchari albi, 2j. Pulveris gummi Arabici, 3'j- Aquae destillatae, gvj. Fiat mistura.—Signa.—A table-spoonful to be given every hour or two hours. Mixture with Musk, &;c. R. Mistura? Moschatae, %vj. Tincturae Opii camphorata?, 5ss. -------- Veleriana? ammoniatae, ?j. Misce.—Signa.—A tea-spoonful three or four times a-day. For chil- dren in pertussis. Tincture of Asafoetida, Castor, fyc. R. Tinctura? Asafcetidae, --------Castorei, aa. gss. Aquae Ammoniae, rij. Misce.—A tea-spoonful may be taken in a glass of water for a dose. Hoffman's Anodyne and Laudanum. R. Liquoris Anodyni Hoffmani, giij. Tinctura? Thebaicae, gtt. lxxx. Aqua? Cinnamomi, ?vj. Fiat mistura.—Signa.—A table-spoonful every one or two hours. In hysteria, &c. Mixture with Asafoetida, $c. R. Asafoetida?, 3j. Aqua? Mentha? piperita?, 5iss. Fiat solutio, et adde— Tinctura? Valeriana? ammoniata?, 3ij. --------Castorei, 3iij. iEtheris sulphurici, 3j. Signa.—A table-spoonful for a dose every second hour. In hysteria. antispasmodics. 159 Infusion of Valerian. R. Valerianae radicis, gj. Aquae bullientis, Oj. Put them into a covered vessel and let them stand until cold.—Dose a wine-glass full every two or three hours. Tincture of Valerian and Hoffman's Anodyne. R. Liquoris Hoffmani Anodyni, Tinctura? Valerianae, aa. ?i. Misce.—Signa.—A tea-spoonful for a dose, pro re nata, shaking the phial each time. Mixture with Ether and Laudanum. R. ^Etheris Sulphurici, gij. Sacchari albi, Gummi Acacia?, aa. 3iss. Tincturae Thebaicae, gtt. lx. Aquae Cinnamomi, gij. Misce.—Signa.—A tea-spoonful every hour. In cramp of the sto- mach, &c. Solution of Boracic Acid, fyc» R. Syrupi simplicis, gj. Acidi boracici, 3j. Infusionis Tilia? vel foeniculi, giv. Misce.—Signa.—A small table-spoonful three or four times a-day. The above is employed by the French physicians in cerebral affections. Ratier. Asafcetidae. Enema. R. Asafcetidae, 3ij. Decocti Avenae, gx. vel Sxij. Misce pro enemate.—Tine. Opii may be added pro re nata. In hys- teria, spasmodic colic, &c. 160 ANTISPASMODICS. Musk Clyster. R. Moschi, gr. xij. Sacchari purificati, 9ij. Gummi Acacia? contriti, 9jss. Alcoholis ammoniati, gtt. xxx. Infusionis Lini, 5iv. Fiat enema.—For children seized with convulsions. Confection of Opium, Sj-c. R. Confectionis Opii, 3vj. Tincturae Camphorae, 3x. Aceti destillati, 5ij. Misce.—To be applied as a plaster warm to the region of the stomach. In vomitings, &c. Opiate Plaster. As under Narcotics. Hemlock Plaster. As under Narcotics. Tobacco Clyster. As under Cathartics. ( 161 ) CLASS XIII. SIALAGOGUES. Those medicines which increase the salivary secre- tion are denominated Sialagogues. In forming these into a class in this place, we trespass somewhat upon the arrangement of Dr. Chapman, but merely from a motive of convenience; for we agree with him that such a class is better expunged from the Materia Me- dica, at the same time that it appeared necessary to introduce it here, in order to place the mercurial pre- parations in stronger relief than could otherwise be done. Pills of Calomel. R. Hydrargyri Chloridi mitis, gr. xij. Conserva? rosarum, q. s., fiant pilula? xij. Signa.—One morning and evening, and if necessary until salivation is excited. Pills of Corrosive Sublimate. R. Chloridi corrosivi Hydrargyri, ------- Ammoniae, aa. gr. v. Aquae destillatae, gtt. xxx vel xl. Conservae rosarum, gj. Pulveris Glycyrrhizae, q. s., ut fiant pilulas xl. Of which, give one pill three or four times a-day. In lues venerea. 21 162 SIALAGOGUES. Dupuytren's Antisyphililic Pills. R. Deuto-chloridi hydrargyri, gr. ss. Extracti cinchona?, gr. x. ------- Opii, gr. ss. Pulveris cinchona?, q. s. Ut fiant pilulae ij.—The two pills may be taken, one in the morning and the other at night; but as each contains a quarter of a grain of sublimate, their action must be closely watched. M. Dupuytren was partial to these pills in the treatment of Syphilis. He thought the opium and cinchona promoted and beneficially modified the ac- tion of the sublimate. Pills with Corrosive Sublimate and Hemlock. R. Chloridi corrosivi Hydrargyri, gr. vj Solvanturin— Aqua destillata, q. s. et adde— Succi Conii spissati, 3j. cum Pulvere Conii, q. s., ut fiat massa, in pilulas xlviij dividenda. These pills contain the same quantity of mercury as the former, and may be given in the same number, and for the same purpose. Pills of Acetate of Mercury. R. Acetatis Hydrargyri, Manna? optima?, Pulveris Acacia?, aa. 9j. Aquae rosarum, q. s., ut fiant pilulae, xx. Of which let three be taken every night, till a gentle salivation is ex- cited. This preparation is said to be the mildest of the mer- curial salts, and is less apt to disturb the bowels; but it is believed to be less efficacious in arresting the ve- nereal disease. The effect of the mercurial preparations upon chil- dren is sometimes very serious, and even fatal. So powerful upon them is the action of this medicine, that a profuse, or even gentle salivation, will sometimes SIALAGOGUES. 163 produce mortification and destruction to the jaw, cheek, and lip. This, however, does not often hap- pen, but is such a shocking occurrence, that the gums should be frequently and carefully examined whilst they are taking mercury. It is, nevertheless, a fact, that a disease precisely similar in all its features occasionally attacks children who are badly clothed and fed, though no mercury has been given to them. Solution of Cyanide of Mercury. R. Hydrargyri cyanidi, gr. viij. Aqua? destillatae, fly. Fiat solutio.—This is the Liqueur Anti-Syphilitique of Chaussier, who prefers it to corrosive sublimate on account of its greater solubility and more speedy action. By giving a tea-spoonful of the solution we give one-eighth of a grain of the cyanide, which may be repeated morning, noon and night, watching its effects. Pills of Iodide of Mercury. R. Iodidi hydrargyri, gr. v. Confectionis rosae, q. s. Ut fiant pilulae, xxx. Each pill will contain the sixth of a grain, which may be given three times a-day. Double the quantity (two pills) is sometimes admi- nistered at first, but care should be taken not to push it too far. Compound Pills of Proto-Iodide of Mercitry. R. Proto-iodidi Hydrargyri, gr. iij. Extracti Opii, gr. ij. Lactucarii, gr. xij. Extracti guiaci, gr. xxiv. Misce, et fiant pilulae, xxiv.—Given by M. Ricord in the syphilis of children. He directs one pill for a child six months old, and two, three, or four pills for older children. Dunglison, New Rem. p. 280. Pills of Proto-Iodide of Mercury. R. Proto-iodidi Hydrargyri, gr. j. Extracti Juniperi, gr. xij. Pulveris Glycyrrhizae, q. s. 164 SIALAGOGUES. Ut fiant pilulae, viij.—In adult patients Majendie directs two to be given morning and evening, to be increased to three or four. Dunglison, ut supra. Pills with Calomel, Camphor, fyc. R. Hydrargyri chloridi mitis, Camphorae, aa. 3j. Pulveris Opii, gr. xij. Syrupi simplicis, q. s.—ut fiant pilula? xx. Signa.—One or two to be taken morning, noon and night. In cases where calomel by itself causes purging. Blue Mercurial Pills. R. Massa? ex Hydrargyro, 9iss. Divide in pilulas, xij. Signa.—One may be taken three or four times a-day, according to circumstances. If they should produce any effect upon the bowels, not desired, Pulv. Opii. gr. ss. may be added. The mass directed in the American Pharmacopoeia con- tains one grain of mercury in every two and a half grains. One grain is contained in four of the Edin- burgh—and in three of the London and Dublin. Powder of Mercury and Chalk with Ipecacuanha. R. Hydrargyri cum creta, 9j. Pulveris Ipecacuanhae, 9ss. Misce.—Fiant chartulae, vj. Signa.—One night and morning in sirup, Recommended by Dr. Paris, in those cases of dys- pepsia in which the biliary secretion is impaired. He prefers it under these circumstances to every other form of mercury. Compound Powder of Sulphate of Mercury. R. Hydrargyri flavi sulphatis, gr. j. Pulveris Asari, 3iss. Misce et divide in chartulas, viij. SIALAGOGUES. 165 Signa.—One of these may be used as an Errhine, morning and evening. In Gutta Serena, Ozoena, and after the removal of Polypi. Pills of the Red Oxide of Mercury. R. Oxidi Hydrargyri rubri, gr. iij. Pulveris Opii, gr. j. Olei Caryophilli, gtt. ij. Fiant pilula? iij.—Signa.—One pill every night for a week. In vene- real cases. This preparation was formerly used by the cele- brated J. Hunter; but from its harshness it is now generally superseded by others. Mixture with Muriate of Mercury. R. Chloridi Hydrargyri corrosivi, gr. ij. Aquae destillatae, 5vj. Spiritus Cinnamomi, Syrupi simplicis, aa. ^j. Misce.—Dose.—One or two large spoonsful, twice or thrice a-day. In venereal cases. Mercurial Solution. R. Chloridi Hydrargyri corrosivi, gr. xvj. Alcoholis, gss. Aquae destillatae, Oj. Misce.—This is the celebrated Liquor of Van Swieten, who directs half an ounce of it to be taken morning and evening, in milk, solu- tion of gum or sirup. Its use requires caution. In venereal affec- tions. Spirituous Solution of Corrosive Sublimate. R. Chloridi corrosivi Hydrargyri, gr. ij. Spiritus vini tenuoris, giv. Solve.—Of which a table-spoonful, night and morning, may be taken in a draught of decoction of Sarsaparilla. 166 SIALAGOGUES. The muriate of mercury is decidedly preferred by some physicians in the treatment of syphilis. John Hunter was of opinion, however, that the disease was more liable to recur, after its use, than when some of the other preparations had been employed. Strong Mercurial Ointment. R. Unguenti Hydrargyri fortis, gj. One drachm of this ointment to be rubbed on the inside of the thighs, before the fire, every night. It is by some physicians recommended to employ the warm bath before using this ointment, while others consider it useless. We think the practice may oc- casionally be beneficial. The hands of the person rubbing it on, if it be an attendant, should be enve- loped in a bladder, or gloves made of oiled silk. Strong Mercurial Ointment with Camphor. R. Unguenti Hydrargyri fortis, gj. Camphorae, gj. Misce.—To be employed as the former. Masticatory with Pellitory, fyc. R. Pulveris Radicis Pyrethri, Resina? Mastichi, aa. gj. Let these be dissolved together by a moderate application of heat: then divide the mass into two equal parts. One of these lumps may be chewed at pleasure. In toothach and paralytic affections of the tongue. Mixture of Pellitory, Opium, fyc. R. Radicis Pyrethri contusae, gss. Aceti destillati, gvj. Gummi Opii, gr. iij. Digest in a sand bath for an hour.—Signa.—A spoonful to be held in the mouth and frequently renewed. Used in the same cases as the former. There are several other substances, such as polygala senega, nitric acid, &c, which occasionally excite SIALAGOGUES. 167 salivation; but as this is simply one effect of these remedies, and one of little consequence, they are treated of under more appropriate heads. Mercurial Lotion. R. Chloridi Hydrargyri corrosivi, 3j. Aqua? destillatae, 3vj. Solve et adde— Muriatis ammoniae, 3ij. Potassa? nitratis, gss. Fiat lotio.—Principally used as a wash in itch. Good's Study of Med. vol. iv. Antacrid Tincture. R. Guaiaci pulveris, 3j- Balsami Canadensis, 3j« Hydrargyri chloridi corrosivi, 9j. Olei Sassafragis, 3ij. Spiritus Vini Rectificati, 3viij. Dissolve the Corrosive Sublimate in one-half the spirit, and then add to it the other ingredients.—Signa.—Of this from ten to twenty drops may be taken morning and evening, in wine or water. This form of exhibiting corrosive sublimate is of ancient date; and has been lately employed by Dr. Emerson and other practitioners of this place in lues venerea, &c. Antacrid Ointment. R. Hydrargyri Oxidi rubri, gss. —--------Chloridi corrosivi, gij. Acetatis Plumbi, gj. Cerae Alba?, 3iv. Olei olivarum, gvj. Olei Bergamotta gtt. xx. Rub the two mercurial preparations with water to an impalpable pow- der__then dry them, and add the acetate of lead. Melt the oil and wax together, and add the other ingredients gradually—stirring the mixture. 168 SIALAGOGUES. This ointment has some celebrity in the cure of tet- ter, and some other obstinate cutaneous diseases. Ointment of Red Precipitate, #c. R. Oxidi Hydrargyri rubri, gr. x. Sulphatis Zinci, 9j. Axungiae purificata?, gij. Fiat unguentum. Recommended by Professor Dupuytren in obstinate chronic ophthalmia depending on a scrofulous dia- thesis. Anti-herpetic Ointment. R. Sulphatis Hydrargyri flavae, 3j. Tinctura? Opii, gj. Sulphuris sublimati, gss. Axungiae, gj. Fiat unguentum.—This has been successfully used in herpes, alter- nated with the simple water bath by M. Cullerier. Ointment of Deulo-ioduret of Mercury. R. Deuto-iodureti Hydrargyri, gr. xv. Adipis preparatae, gij. Olei limonis, gtt. xx. Fiat unguentum. This ointment has been found highly efficacious in syphilitic tubercles, or chronic ulceration of a syphili- tic character, but its great activity requires close at- tention. The following formula, which is much less active, may be employed with less inconvenience. R. Proto-iodureti Hydrargyri, 3ss. Adipis praeparatae, 3iss. Olei, gtt. xv. Fiat unguentum.—Syphilitic ulcerations which have resisted a variety of remedies, have cicatrized rapidly under the use of this ointment. Ratier. SIALAGOGUES. 169 Ointment of Cyanuret of Mercury. R. Cyanureti Hydrargyri, gr. xvj. Adipis praeparatae, 3j- Essentia; citri medicae, gtt. xv. Fiat unguentum.—Used in Herpes, attended by intense inflammation and itching. 22 ( 170 ) CLASS XIV. TONICS. Those medicines are considered Tonics which im- part strength to the system, without subjecting it to any preternatural excitement during their operation. They stimulate, however, in a secondary manner, by gradu- ally increasing the force of the circulation, and by re- storing the digestive and secretory functions to a more healthy state. Considerable perseverance is often ne- cessary in giving any one of this class a fair trial; and when one fails, we may often resort with success to another: much also may sometimes be gained by alter- nating them. POWDERS, &c. Powder of Peruvian Bark. R. Pulveris Cinchona? optima?. A drachm or a tea-spoonful to be taken every hour in port-wine, wa- ter, or milk, during the intermission of fever and ague. It is directed by some practitioners to suspend the bark till within a few hours of the expected paroxysm; and by a few others to administer it during the hot stage of the disease. We have generally found it to be the most successful plan to commence immediately after the paroxysm has ended, and give every hour a TONICS. 171 dose of the remedy, until the expected period of its return; and if the chill does not recur, to continue it in smaller quantities for several days. Powder of Peruvian Bark and Cloves. R. Pulveris Cinchona?, Super-tartratis Potassa?, aa, 3j. Pulveris Caryophilli, 3j. Misce.—Dose.—A drachm and a half every second hour. This compound will sometimes succeed when the bark alone fails. Powder of Peruvian Bark and Sulphate of Magnesia. R. Pulveris Cinchona?, Sulphatis Magnesiae, aa. 3vj. Fiat pulvis, et divide in partes aequales iv.—One to be taken every two hours, where purging is required. Powder of Peruvian Bark, Snake Root, <$c. R. Pulveris Cinchona?, 3ss. --------Serpentariae, 3j. Sodae Bi-carbonatis, gr. xl. Misce.—Divide in chartulas iv.—Signa.—One to be given every two hours. In obstinate intermittents. If the bark should purge when given alone, a little opium may be added : when it oppresses the stomach, cloves, as in a former prescription. If costiveness should follow, rhubarb, or sulphate of magnesia may be used. The alkali in the above preparation will cor- rect acidity. Powder of Augustura Bark. R. Pulveris Cusparia? febrifuga?, 3ss. Divide in chartulas vj.—Of which one may be taken three or four times a-day, in water or any other vehicle. 172 TONICS. This remedy, we learn, has been successfully em- ployed in uterine hemorrhage. Powder of carbonate of Iron. R. Pulveris carbonatis Ferri praecipitati, gj. Divide in chartulas iv.—Signa.—One every six hours in molasses. In Chorea, Neuralgia, &c. The above remedy, we are told, has been success- fully used in these very painful affections, both in England and America. The dose is sometimes car- ried as far as 3ss. every four or six hours, after anti- phlogistic treatment, if the latter be required. Powder of Colombo, Ginger, $c. R. Pulveris Colombae, --------Carbonatis Ferri praecipitati, --------Rhei, --------Zingiberis, aa. 3j. Misce.—Fiant doses xij.—One to be taken three times a-day, in mo- lasses. Powder of Colomba and Tartrate of Iron. R. Tartratis Ferri, 9ij. Pulveris Colombae, 3j. Fiant pulveres iv.—Signa.—One every three or four hours, in sirup. ! Powder with Rust of Iron, fyc. R. Sulphatis Ferri, 9ij. Carbonatis Ferri praecipitatis, 3iss. Divide in pulveres xij.—Signa.—One to be taken morning, noon and night, in sirup or molasses. Pilts of Cinchona and Camphor. R. Extracti cinchona?, 3j. --------Opii, gr. j. Gummi camphorae, gr. xij. Pulveris cinchonae, q. s, Ut fiant filula? xij.—One to be taken three or four times a-day. Ratier. TONICS. 173 Powder of Prussiate of Iron and Guaiacum. R. Ferrocyanatis Ferri, Pulveris Guaiaci, aa. 3j- Misce et divide in chartulas xij.—Signa.—One three times a-day. This prescription has been successfully employed in obstinate intermittents. Pills of Extract of Burk, &/c» R. Extracti Cinchona?, --------Gentianae, aa. 3j. Sulphatis Ferri, 3ss. Pulveris Myrrhae, 3y Olei Carui, gtt. x. Syrupi Zingiberis, q. s., ut fiant pilulae lx. Signa.—Three to be taken three times a-day. Pills of Sulphate of Quinia, &/c. R. Sulphatis Quiniae, gr. x. Conservae Rosarum, q. s., ut fiant pilula? x. Signa.—One to be given every hour in the apyrexia of intermittent fever. There is also another principle obtained from the cinchona lancifolia, or pale bark, which possesses very nearly the same powers as the first. This is called Cinchonia. These preparations produce all the effects of the Peruvian bark, and have now almost entirely superseded it. The sulphate of quinia affects the chest of the consumptive patient with tightness in an equal degree with the bark; and we have several times observed it to produce a soreness of the mouth exactly resembling that resulting from mercury. The obser- vations of some of our friends have confirmed this fact. A substance has lately been discovered in the bark of the willow, (Salix helix,) which is proved not to be alkaline, but which answers all the purposes of quinia in the cure of intermittent fevers. It is called salicine, 174 TONICS. and has been used both in France and Italy.— Vide Journal of the Philadelphia College of Pharmacy, Vol. II. No. 3. Pills of Salicine. R. Salicinae, gr. xxiv. Mucilaginis, q. s. Ut fiant pilula? viij.—A pill to be taken three or four times a-day. Salicine is obtained from willow bark (salix helix.) It has been chiefly used in intermittent fever, and produces effects very similar to those of Quinia. Pills of Ammoniuret of Copper. R. Cupri ammoniati, 9j. Conserva? rosarum, q. s., ut fiant pilulae xxx. Signa.—One or two to be taken at bed-time. In Epilepsy. Pills of Sulphate of Quinia and Carbonate of Ammonia. R. Sulphatis Quinia?, gr. xij. Carbonatis Ammoniae, gr. xxiv. Misce.—Fiant pilulae vj.—Signa.—One every hour, beginning six hours before the expected paroxysm. These pills are large, but we have succeeded with them when quinia alone and in smaller doses had proved unavailing. They may also be combined ad- vantageously with the oil of black pepper, or other essential oils, in cases of irritable stomach. Febrifuge Boluses. R. Pulveris Cinchona?, gj. Muriatis Ammoniae, Carbonatis Ammoniae, aa. gr. xij. Tartratis Antimonii, gr. xviij. Syrupi simplicis, q. s., ut fiat massa et divide in bolos xlviij. Signa.—One to be taken four times a-day, during the apyrexia of fever- Hotel Dieu. TONICS. 175 Pills of Pipcrina R. Piperina? puree, gr. xij. Extracti Gentianae, q. s., ut fiant pilulas xij. Signa.—One every hour during the apyrexia of fever. This is one of the new remedies lately introduced into practice. It is prepared from the black pep- per, and is said to possess considerable febrifuge powers. It sometimes vomits, purges, or produces diaphoresis; and therefore requires caution in its ad- ministration. It may be given in mixture, if preferred. Pills of Arsenic, &;c. R. Acidi arseniosi, gr. ij. Pulveris Opii, gr. iij. Saponis venetae, gr. viij. Pulveris Glycyrrhizae, q. s., ut fiat massa in pilulas xx dividenda. Signa.—One four times a-day, increased gradually according to cir- cumstances. In intermittent fever and local diseases of an intermit- tent character. Dr. Meigs. Pills with the Sulphate of Copper. R. Sulphatis Cupri, gr. iv. Extracti Cinchona?, gr. xxxij. Syrupi simplicis, q. s., ut fiat massa, in pilulas xvj dividenda. One to be taken four times a-day. In obstinate intermittents. Pills of the Oxide of Bismuth. R. Sub-nitratis vel oxidi Bismuthi,gj. Mucilaginis gummi Acacia?, q. s., ut fiant pilulae xxx. Signa.—One to be taken every two hours. In dyspepsia. Pills of Muriate of Ammonia, Arsenic, fyc. R. Muriatis Ammoniae, 3ss. Pulveris Opii, gr. viij. Acidi arseniosi, gr. vj. Syrupi simplicis, q. s., ut fiant pilulae xxxij. Of which one may be given three times a-day. In intermittent fever. 176 TONICS These pills are strongly recommended by some practitioners. Great care is requisite in preparing them. Pills of Ammoniated Iron, &;c. R. Ammoniati Ferri, 9j. Pulveris Rhei, gr. viij. Conservae rosarum, q. s., ut fiat massa in pilulas v dividenda. This remedy is recommended in Rachitis, and is to be continued with one pill a-day for a fortnight, and then intermitted for the same length of time and again resumed. The intention of this direction ap- pears to be to prevent the system from becoming ha- bituated to the medicine. Pills of Oxide of Zinc. R. Oxidi Zinci, gij. Conserva? rosarum, q. s., ut fiant pilulae x. Signa.—One three or four times a-day. In epilepsy, chorea, &c. Dr. Chapman speaks favourably of this medicine, and recommends to begin with the above dose, and gradually to increase it. Pills of Steel Filings. R. Limatura? Ferri, gr. xvj. Extracti Gentianae, q. s., ut fiat massa.—Divide in pilulas vj. Signa.—One three times a-day, followed by a draught of some bitter infusion. Pills of the Extract of Quassia. R. Extracti Quassia? mollis, 3j- Pulvaris Gentianae, q. s., ut fiant pilulae xx. Of which one may be taken three or four times a-day, succeeded by a wine-glassful of the infusion of quassia. This is one of the purest bitters, and where we wish the effect of this class only, we cannot select a more appropriate preparation. TONICS. 177 Pills of Nitrate of Silver, Sj-c. R. Nitratis Argenti, gr. iij. Pulveris Opii, 3ss. ------- Camphorae, ------- Nucis moschatae, aa. 9j. Mucilaginis Acacia?, q. s., ut fiat massa.—Divide in pilulas xlv. Dose.—One morning and evening. In chorea and epilepsy. Pills of the Sulphate of Iron. R. Sulphatis Ferri, 3J- Extracti Gentianae, q. s., ut fiat massa.—Divide in pilulas, xxx. One to be taken morning, noon and night. In dyspepsia. Pills of Nitrate of Silver. R. Nitratis Argenti, gr. iij. Mica? panis, gss. Aquae fontanae, q. s., ut fiant pilulae xij. Signa.—One to be taken night and morning, gradually increasing them as the case may demand. The nitrate of silver should first be dis- solved in a little water, and the crumbs of bread afterwards added; and a glass mortar should always be employed to compound them in. Electuary of Cinchona, Rust of Iron, 8fc. R. Pulveris Cinchona? optima?, ------- Carbonatis Ferri, aa. gj. Balsami Copaiva?, q. s., ut fiat electuarium. To be made (by the patient) into pills of the ordinary size. Of which four may be taken three times a-day. Pills of the Nitro-Muriate of Gold. R. Nitro-muriatis Auri, gr. v. Pulveris Glycyrrhizae, giss. Mucilaginis Acaciae, q. s., ut fiat massa, in pilulas lxxv. divi- denda. Signa.—One or two thrice a-day. In syphilis, &c. This metal is placed under the head of tonics by Dr. Chapman, and we have followed his example. Although once much extolled, it is now seldom used. 23 178 TONICS. Pills of Ammoniuret of Copper and Extract of Quassia. R. Cupri Ammoniati, gss. Extracti Quassia? mollis, 3iss. Misce, et divide in pilulas xxx.—Of which one may be taken three times a-day. In nervous diseases. MIXTURES, &c. Griffth's Myrrh Mixture. R. Gummi Myrrha?, 3j. Sulphatis Ferri, 9j. Carbonatis Potassae, 3J. Sacchari Purificati, 3ij. Aquae destillatae, gvj. Fiat mistura.—Dose.—A table-spoonful according to circumstances. Employed as a tonic in phthisis. Mixture of Sulphuric Acid, Src. R. Sulphatis Ferri, gr. ij. Acidi sulphurici, gtt. x. Sacchari albi, 3j« Aquae destillatae, gj. Misce.—Signa.—A tea-spoonful for a dose, to be repeated every two, three, or four hours. Designed for children. Vinous Infusion of Carbonate of Iron, 8fc. R. Carbonatis Ferri Praecipitatis, 3iss. Pulveris radicis Gentianae, Corticis Aurantii contusae, aa. iiss. Vini Lusitanici rubri, Oij. Macerate for two or three days, and give a wine-glassful two or three times a-day. In dyspepsia arising from intemperance. Mixture with Tincture of Bark and Citrate of Potash. R. Succi Limonis recentis, gjss. Carbonatis Potassae, 3j. Tincturae Cinchona?, gj. Aquae Cinnamomi, giij. TONICS. 179 Misce.—Signa.—A table-spoonful every two hours. In cases in which it is desirable to promote insensible perspiration whilst taking the bark. Infusion of Sage and Boneset. R. Saliva? officinalis, Eupatorii perfoliati, aa. gss. Corticis Cascarillae, gj. Misce.—Infuse in three half-pints of water until cold. Dose.—A wine-glassful every three or four hours. In Hectic Fever Decoction of Cinchona. R. Corticis Cinchona? contusae, 3j. Aqua? frigidae, Oj. Boil for ten minutes—and while hot add— Surpentariae radicis, 3ss. Corticis Aurantii contusae, 3ij. And suffer them to infuse for half an hour near the fire in a covered vessel.—Dose.—A wine-glassful every hour. If the bark be boiled longer than ten minutes, it deposites extractive and resinous matter, becomes paler, and is less efficient. The last ingredients are directed to be infused because their aromatic proper- ties would be dissipated by decoction. Decoction of Bark, fyc. R. Decocti Cinchona?, 3vj. Tincturae Cinchona? Huxhami, 3j. Acidi sulphurici aromatici, gtt. xl. Misce.—A table-spoonful may be taken every one or two hours pro re nata. By this preparation we obtain the extract, both aqueous and alcoholic, of the bark. Sulphate of Quinia in Sirup. R. Sulphatis Quinia?, gr. xv. Acidi sulphurici, gtt. vj. Surupi Zingibe vel Limonis, 3ij. 180 TONICS. Misce.—Signa.—A large tea-spoonful may be given every hour during the apyrexia. The French physicians employ a wine and tincture of quinia, which, however, are not superior to the com- pound used in this country. Both in Europe and America, and especially in Italy, the dose is carried to a much greater amount than we have directed. Eight, ten, fifteen, twenty, and thirty grains have been given by the Italians without danger and with success. Such doses many persons cannot bear, and generally the cure can be accomplished with sixteen grains in twenty- four hours. Mixture of Sulphate of Quinia. R. Sulphatis Quinia?, gr. xvi. Acidi sulphurici, gtt. v. Sacchari albi, 3j. Aqua? Cinnamomi, gijss. Misce.—Signa.—A tea-spoonful for a dose, every hour during the apyrexia of intermittents. By the addition of sulphuric acid, a super-sulphate of quinia is formed, which is soluble in the aqueous menstruum. Tincture of Quinia. R. Quininae, 9j. Alcohol, 3ss. Fiat tinctura.—Dose.—Ten to twenty drops every hour. Ferrocyanale of Quinia. R. Ferrocyanitis quinia?, gr. iv. Spiritus rectificati, 5J« Solve et adde— Aquae camphorae, 3vij. Misce.—This preparation is said to be more active than the sulphate, whence it should be given in less doses: a tea-spoonful of the solu- tion (which will contain half a grain of the salt) may be taken every TONICS. 181 hour or two hours, according to circumstances.* Pills of the Fer- rocyanate of Quinia are prepared with simple mucilage, and admi- nistered like the sulphate. The acetate, citrate, muriate and nitrate of Quinia, have also been employed in Europe, and occasionally in this country. They possess no advantages over the ordinary preparations, and are given in much the same quantity. Sirup of Cinchonine. R. Sulphatis Cinchoninae, gr. xxiv. Syrupi simplicis, Oss. Fiat mistura.—A table-spoonful will contain nearly a grain and a-half of the salt, which is a full dose; to be repeated pro re nata. Cinchonine is also and more readily administered in pills of a grain or two grains each. In intermittent fevers. Mixture of Red Bark in Port Wine, fyc. R. Pulveris Cinchona? oblongifoliee, 5ss. Theriaca? Andromachi, 3j- Succi limonis, 31J. Vini Lusitaniae, 3iv. Misce.—Signa.—A wine-glassful every second hour during the apy- rexia. We find this prescription strongly recommended in the JY. A. Medical and Surgical Journal, by Dr. Meigs, in intermittent fever. Mixture with Decoction and Tincture of Bark, fyc. R. Decocti Cinchona?, 5iij. Tinctura? Huxhami, ^j. Pulveris Cinchona?, 3ij. Syrupi simplicis, 3ss. Fiat mistura.—A table-spoonful to be taken every one or two hours during the absence of fever. * Vide Dunglison, New Remedies, p. 408 182 TONICS. Mixture with Extract of Bark, $c. R. Extracti Cinchona?, 3j- Decocti Cinchona?, gvj. Tincturae Cardamomi, giv. Misce.—A table-spoonful for a dose, as above directed. Tincture of Cinchona, Valerian, &/c. R. Tinctura? Cinchona?, --------Valerianae, aa. ^j. -------- Cardamomi, zij. Aquae menthae, 5iv. Fiat mistura.—Of this mixture a table-spoonful may be given every third hour. This preparation is especially designed as a tonic in nervous temperaments. Mixture of Fowler's Solution, §c. R. Liquoris potassae arsenitis, gtt. lx. Tincturae Opii, gtt xxx. Spiritus Lavendula? compositi, gj. Aqua? Cinnamomi, giij. m Fiat mistura.—Signa.—A table-spoonful for an adult, a tea-spoonful for a child; to be administered every two hours, during the apyrexia of intermittents. Arsenical Mixture. R. Liquoris arsenicalis, gtt. x. Aqua? destillatae, 5j. Tincturae Opii, gtt. x. Spiritus lavendula? compositi, 3ss. To be taken at a dose. This mixture is recommended by Dr. Graves, when the simple arsenical solution irritates the stomach. Acidulated Tincture of Gentian. R. Tinctura? Gentianae compositae, gj. Acidi sulphurici aromatici, 3j. TONICS. 183 Misce.—A small tea-spoonful may be taken in sugar and water, three or four times a-day. In dyspepsia. Tincture of Bark. R. Tincturae Cinchonae compositae, gj. Signa.—A tea-spoonful for a dose, every two hours. In the same doses as the above may be taken. Tinctura Colombae—et Tinctura Gentianae composita. Muriated Tincture of Iron. R. Tinctura? Ferri muriatis, 3j- From twenty to sixty or eighty drops may be taken in a glass of cold chamomile tea, twice or thrice a-day. Infusion of Colomba and Ginger. R. Radicis Colomba? contusae, gj. ------Zingiberis, 3ij. Aquae bullientis, Oj. Fiat infusio.—Give of the strained liquor, (cold,) a wine-glassful every two hours. This infusion, when freely used, has proved success- ful in chronic diarrhoea. Infusion of Colomba, Rhubarb, §-c. R. Seminum Carui contusorum, Radicis Colombae, ------Rhei, aa. 9J. Aqua? ferventis, gviij. Digest for two hours, and strain. R. Liquoris colati, giijss. Tincturae Rhei, 3j. Syrupi Zingiberis, 3ij. Misce.—Dose.—A tea-spoonful to a table-spoonful for children, ac- cording to their age. In Diarrhoea. 184 TONICS. Mixture of Sulphate of Iron and Elixir of Vitriol. R. Ferri sulphatis, gr. iv. Acidi sulphurici aromatici, gtt. xl. Aquae destillatae, gj. Fiat mistura, et signa.—A tea-spoonful to be taken three times a-day in half a wine-glass of water. Vinegar Draught. R. Acidi acetici, gj. Tinctura? cardamomi composita?, gss. Syrupi simplicis, 3ss. Aquae, 3x. Misce.—To be taken every twenty minutes as a draught. Advised by Dr. Howard, of London, in sick headach. Acorn Coffee. R. Pulveris Glandis torrefactae, 3j. Aquae bullientis, Oj. Fiat infusio.—Three or four tea-cupsful may be taken during the day, and augmented according to circumstances. The above is a very favourite remedy with the Ger- mans. " It is one of the most successful in mesenteric atrophy, commencing rachitis, glandular swellings, asthma, and cough. Continued for a long time, it is one of the most powerful means we possess, for de- stroying the scrofulous disposition."—Hufeland's Trea- tise, p. 215. Infusion of Quassia. R. Ligni Quassia?, Radicis Serpentariae, Corticis Aurantii contusae, aa.. 5ss. Aqua? bullientis, Oij. Fiat infusio et cola.—Of which a tea-cupful may be taken cold, three times a-day. Decoction of Bark and Valerian. R. Corticis Cinchona? contusae, ?j. Boil in a pint of water for ten minutes, and strain. TONICS. 185 R. Radicis Valerianae contusae, gj. Aquae bullientis, Oj. Infuse for one hour and strain.—Add the decoction of bark to this in- fusion, and give a tea-cupful cold, three or four times a-day. This was a favourite prescription with Dr. Parrish, in certain cases of headach, which appear to depend upon rheumatism, and which are entirely unmanageable with the lancet, purgatives, &c. &c. Infusion of Chamomile and Orange Peel. R. Florum Anthemidis nobilis, 3J. Corticis Aurantii, ?ss. Aqua? frigidae, ftjiij. Macerate for twenty-four hours.—Dose.—A tea-cupful three or four times a-day. The infusion of chamomile made with cold, is in general more grateful to the patient than when made with boiling water; the same remark applies to infu- sions generally, and they are also less liable to fer- ment when made with cold water. Decoction of Anguslura Bark. R. Corticis Cusparia? febrifuga? contusae, 5j. Aquae fontanae, Ojss. Boil for fifteen or twenty minutes, and strain.—Of this decoction a wine-glassful may be taken every two hours. Decoction of Wild-Cherry Tree Bark. R. Corticis Pruni Virginiani contusi, 5j. -------Aurantii contusae, 3'j- Aqua? fontanae, Oj. Boil the bark alone for half an hour, and then add the orange-peel.— A wine-glassful may be taken every hour or two in consumptive cases, asthma, Sic. Infusion of Serpenlaria. R. Serpentaria? Virginianae, gss. Aqua? bullientis, Oj. 24 186 TONICS. Infuse in a covered vessel for one hour.—A wine-glassful every hour or two hours, pro re nata. Compound Tincture of Aloes, Gentian, S,-c. R. Aloes socotorinae, 3j- Pulveris Zedoariae, ------- Gentianae, ------- Croci, ------- Rhei, ------- Agarici, Syrupi, aa. gj. To be mixed into a quart of brandy. This is the celebrated Baume de Vie, or Elixir of Life. It is a powerful tonic, and one of the most effectual febrifuge medicines. In intermittents, especially, it is justly celebrated. Dose.—A table-spoonful three times a-day. Infusion of Sage and Boneset. R. Salvia? officinalis, Eupatoria? perfoliatae, aa. gss. Corticis cascarillae, gj. Mix, and infuse in three half pints of boiling water until cold. Dose.— A wine-glassful every two or three hours. In the colliquative per- spiration of hectic fever. Decoction of Dog-Wood Bark. R. Corticis Corni Florida? contusae, 3j. Aquae fontana?, Oj. Boil for twenty or thirty minutes, and strain.—A wine-glassful may be given every hour, as a substitute for Peruvian Bark in intermit- tents. Infusion of Hops. R. Humuli lupuli,3j. Aquae ferventis, Oj. Infuse for two hours, and strain by expression. Of this a wine-glassful may be taken three or four times a-day. In dyspepsia. Infusion of Boneset. R. Eupatorii perfoliati, 3j. Aqua? bullientis, Oj. TONICS. 187 Infuse for two hours, and strain.—Of this a wine-glassful may be taken every one or two hours, cold. In intermittent fever. Enema of Extract of Bark, SfC. R. Extracti Cinchona?, 3ss. Aquae tepidae, giv. Solve; dein adde— Olei olivarum, gss. Tincturae Opii, gtt. x. Fiat enema.—Signa.—To be thrown up every fourth hour. In inter- mittents. Where it is preferred, the powdered bark may be used—say 31J. mixed with some of the decoction in- stead of common water. The bark thus administered may occasionally be made to arrest an intermittent when the patient cannot swallow it. Bark is also employed externally in the form of a waistcoat, worn next the skin. A poultice made by mixing the powder and decoction into a paste, is occasionally applied to the region of the stomach; and lastly, the decoction may be used as a semicupium. Enema of Quinine. Quinine is employed in enemata, and in this form has an immediate and powerful effect on intermittent fevers. From eight to twelve grains of the sulphate of quinine, dissolved in a tea-cupful of flax- seed or other mucilage, may be administered at a time, and repeated in twelve hours. Infusion of Cinchona with Lime Water. R. Cinchona? corticis cordifoliae, 3ij- Liquoris calcis, Oij. Misce, et fiat infusio. This infusion was formerly much employed and esteemed as an excellent compound. A wine-glassful may be taken three or four times per diem, or once every hour, in intermittent and other forms of fever. 138 TONICS. GENTIAN IN. This substance is obtained by an elaborate chemical process from the root of the gentiana lutea. It is in- tensely bitter, but possesses no advantages oyer the common preparations of Gentian. Majendie gives two formulae for its administration : R. Gentianinae, gr. v. Alcoholis, 3j- Fiat tinctura.—Dose.—Two tea-spoonsful, which will contain a little more than a grain of the medicine. Commended in scrofulous affec- tions. Sirup of Gentianin. R. Gentianinae, gr. xvj. Syrupi, Oj. Misce.—Dose.—A wine-glassful, which will contain a grain. Compound Infusion of Gentian. R. Radicis Gentiana? concisae, gss. Corticis Aurantii contusae, 3ij. Seminis Cardamomi, gss. Aqua? ferventis, Oj. Fiat infusio. Gentian is an excellent bitter, and the above will prove useful in wine-glassful doses, in debility of the diges- tive organs, &c. ALTERATIVES. Alteratives have been defined—those medicines which are given with a view to re-establish the healthy functions of the animal economy, without producing any active evacuation. This class of remedies, there- fore, embraces numerous preparations which produce a slow but decided effect on the various secreting or- gans, sometimes without any sensible increase of the TONICS. 189 secretions themselves, but in other instances obviously augmenting or magnifying them. Such is the action of minute doses of mercury, iodine and other sub- stances upon the glandular apparatus. These medi- cines are generally classed with stimulants and tonics, and some of them with narcotics, and others have been placed with those preparations to which they seem most allied when given in an over-dose,—Sialagogues, for example. Without attempting to investigate this question farther than regards practical convenience, we proceed in this place to indicate the more active and important Alteratives; merely premising the fa- miliar truth, that medicines of almost every class of the materia medica become alteratives by being ad- ministered in very small doses at intervals of a few hours. Mthereal Tincture of Iodine. R. Iodini, gr. vj. iEtheris Sulphurici, 3j. Misce.—Thirty drops contain one grain of iodine.—Dose.—Ten drops twice or three times a-day. In cutaneous and glandular diseases. Compound Tincture of Iodine. R. Iodinae, gj. Potassa? iodida?, gij. Spiritus rectificati, Oij. Fiat tinctura.—Dose.—Five to fifteen drops, pro re nata. Mixture of the Hydriodale of Potash, ifc. R. Iodidi Potassae, gr. ij. Sulphatis Magnesiae, gss. Tartratis Antimonii et Potassae, gr. ss. Aquae destillatae, gvj. Misce.—Signa.—A tea-spoonful three or four times a-day. In scrofula. Iodine with Hydriodale of Potash. R- Iodinae, gr. iij. Potassa? iodidi, gr. vj. Aqua? destillatae, ^]. 190 TONICS. Solve et signa.—Dose.—Six to ten drops thrice a-day in a wine-glass of cold water. If it produce dizziness, pain in the bowels, or other unpleasant symptoms, diminish the quantity. Dr. Morton (" Illustrations of Pulmonary Con- sumption,") strongly recommends this mixture in catarrh, phthisis, &c. It has a powerful effect in glandular disease, and in all affections of the mucous membranes. Mixture of Tincture of Iodine, fyc. R. Tincturae Iodini, f. 3j. Mucilaginis Acacia?, f. 3ij. Aquae destillatae, f. gvj. Fiat mistura et signa.—A table-spoonful every two hours. Employed in cases of ulceration accompanied by purulent discharge from the meatus auditorius, and where there exists a scrofulous diathesis. See Astringents. Solution of Hydriodale of Iron. R. Iodidi ferri, gj. Aquae destillatae. 3j. Fiat solutio.—Dose.—Six to ten drops morning, noon and night, in a wine-glass of cold water. Solution of Iodide of Potassium. R. Potassii iodidi, gr. xxxvj. Aquae destillatae, gj. Fiat solutio.—Dose.—Five to twenty drops, morning, noon and night, in a wine-glass of sweetened water. Majendie. Solution of the Ioduretted Hydriodale of Potassa. R. Iodinae, gj. Potassii iodidi, 9ij. Aqua? destillatae, gvij. Fiat solutio.—Dose.—Six drops, morning and evening, in a wine- glass of water. In scrofulous and scirrhus diseases. Dunglison, New Remedies, p. 306. TONICS. 191 Tyrrell's Mixture of Ioduretted Hydriodale of Potassa. R. Iodinae, gr. ss. Potassae iodidi, 3ss. Syrupi papaveris, 3ss. Aqua? destillatae, tbss- Fiat mistura.—Given in dose of a wine-glassful three times a-day. In syphilis combined with scrofula. Vide Dunglison, ut supra. Mixture of Iodo-Hydrargyrate of Potassium. R. Hydrargyri deuto-iodidi, gr. iv. Potassii iodidi, 9j. Aquae destillatae, 3j. Misce.—Dose.—Five drops three times a-day, much diluted. Tincture of Iodo-Hydrargyrate of Potassium. R. Potassa? iodo-hydrargyratis, gr. j. Spiritus vini tenuioris, 3j. Fiat tinctura.—Dose.—Ten drops three times a-day, much diluted. Ioduretted Sulphuric Ether. R. Etheris sulphurici, gj. Iodidi puri, gr. vj. Solve.—Thirty drops of this solution contain a grain of Iodine. Six drops constitute a full dose. Majendie's Anti-Epileptic Solution of Iodine. R. Iodureti potassii, 3iv. Iodidi, gr. ij. Aqua? menthae destillatae, 3vj. Fiat solutio.—Dose.—A spoonful thrice per diem. Iodine Waters. The physicians of Europe, and especially of Paris, have made ex- tensive and salutary use of Iodine waters, both internally and exter- nally. In these the Iodine is very much diluted, and generally with the addition of more or less common salt. These waters are prepared 192 TONICS. on a large scale and with great precision by the Pharmaceutists of Paris, but they have been but partially introduced into this country. M. Majendie, however, gives formulae for some extemporaneous Iodine waters, which may answer all the purposes of the more elaborate preparations. The following is an example:— Ioduretted Water. R. Iodureti Potassii, gr. vj. Iodini, gr. j. Aquae purae, Oij. Fiat solutio.—This solution is directed to be drank at meals, in place of common water. That Iodine is one of the most powerful alteratives at present known, there can be no question. There are few diseases dependent upon or connected with morbid secretion of the glandular structures, but what are more or less modified by its use, while in others it acts as a direct curative agent. It is chiefly, however, in scrofulous, glandular and cutaneous affections that it acts most beneficially, dispersing indurations of the glands, and restoring the secretions of the cutaneous and mucous apparatus: whence its advantages in erup- tive diseases, bronchitis, leucorrhcea, amenorrhcea, &c. &c. It has been found to restore suppressed hsemorr- hoidal and catamenial discharges, and when pushed too far, has even produced alarming hemorrhage of the lungs, nose and uterus. These facts should make the practitioner extremely cautious in its administration, beginning with small doses, and watching their effects. Should it produce any of the inconveniences already mentioned, or dizziness, nausea, purging, burning of the skin or swelling of the gums, it should be at once suspended or given less frequently and in smaller doses. It is well known that Iodine was first discovered in sea-weed and sponges; and the latter having long had the reputation of being a cure for Goitre, it was found that Iodine was the active remedial agent. We TONICS. 193 give below two prescriptions for the use of sponge as formerly in vogue, but now nearly superseded by the preparations of pure Iodine. Burnt Sponge. R. Spongiae ustae, 3j- Sacchari albi, ^j. Misce et divide in chartulas, vj.—One three times a-day, gradually . augmenting the dose. In Bronchocele. Decoction of Sponge. R. Spongiae concisae et torrefactae, 3j. Aquae destillatae, Oj. Coque et infunde duodecem horas.—Of this, filtered and rendered palatable by the addition of a little mint water, a table-spoonful or more may be taken every three hours. STRYCHNINE. We have already (under the head of Narcotics) given several prescriptions for using this extremely poisonous substance; but as it is chiefly given as an alterative, we here add some additional modes of administration. Strychnine is now much in vogue in the whole class of nervous diseases, paralysis, whether general or local, neuralgia, chorea, hysteria, &c. It is also employed in syphilis, amenorrhcea, dyspepsia, bronchitis, and in fact, in all cases where an alterative course is indicated. Solution of Acetate of Strychnine. R. Strychnia? acetatis, gr. iij. Alcohol, 3J. Aqua? cinnamomi, ^vij. Misce.—Dose.—Five drops twice a-day, gradually increasing the quantity. Dunglison, New Remedies, p. 450. 25 194 TONICS. Tincture of Acetate of Strychnine. R. Strychnia? acetatis, gr. iss. Alcohol, 5ss. Fiat tinctura.—Dose.—Five to twenty drops thrice per diem. In syphilitic pains of the bones. Dunglison, ut supra. A Sulphate of Strichnine is also in use. It is prepared like the Acetate, of course substituting sulphuric acid. It has no advantages over the preparations already given, and is little used. See Majendie, Formulaire, 9vme. Ed. p. 30. Brucine. The alkaline principle called Brucia or Brucine, is contained in the Augustura bark, Nux vomica and St. Ignatius's bean. That obtained from the bark is pre- ferable for medicinal purposes. It possesses the pro- perties of Strychnia, but in less degree. It may be ad- ministered in doses of one to three grains without dan- ger; but the minimum dose should be first given, and the quantity gradually augmented. Pills of Brucia. R. Brucia? pura?, gr. xij. Conserva? rosarum, q. s., ut fiat massa. Divide in pilulas xxiv. Signa.—One pill may be taken four times a-day, and gradually in- creased. Tincture of Brucia. R. Alcoholis, ±j. Brucia? purae, gr. xviij. Fiat tinctura.—From six to twenty-four drops may be taken in a draught. Mixture of Brucia. R. Bruciae, gr. vj. Aquae destillatae, 5iv. Sacchari albi, gij. TONICS. 195 Fiat mistura. Dose.—A table-spoonful night and morning. These preparations are chiefly used in paralysis, and the entire series of spasmodic affections. Bromine. This substance, which is allied to chlorine and io- dine, is obtained from salt springs and other mineral waters. In medicine it is chiefly used in combina- tion with potassa. Solution of Bromide of Potassium. R. Potassii bromidi, gr. xviij. Aqua? lactuca? destillatae, giij. Syrupi althaea?, ^j. Fiat mistura.—Majendie directs the preceding quantity to be given during the twenty-four hours, in doses of a table-spoonful. It is recommended in scrofula, glandular diseases, amenorrhcea, Sic. Pills of Bromide of Iron. R. Bromidii Furri pulverisate, gr. xij. Conserva? rosarum, gr. xviij. Gummi Arabici, gr. xij. Misce, and fiant pilulae xx secundum artem. Two pills to be taken in the morning, and two in the evening, or, one three times a-day. In Hypertrophy of the Heart, and scrofulous affections. Majendie. Mercury. The mercureal preparations constitute the most de- cided and efficient medicines of this class. In addi- tion to several formulae inserted under the head of Sialagogues, the following will be appropriately no- ticed in this place. Calomel Pills. R. Calomelanos, gr. ij. Conserva? rosarum, q. s., ut fiant pilulae xij. Of which one may be taken every one or two hours. In cases of marasmus, Sic. Sic. 196 TONICS. The use of calomel in minute doses has become very general, and certainly, if we may be allowed to give our experience, very deservedly so. In the he- patic and intestinal complaints of children, it is pro- ductive of the happiest results when carefully ma- naged. In infants, for example, the sixteenth or eighth of a grain, repeated every hour or two hours, according to age and circumstances, will often check diarrhoea, and even dysentery, which have resisted every treat- ment. If the discharges are attended by pain and te- nesmus, small doses of powdered opium or laudanum may be added; but, as a general rule in these cases, the anodyne had better be given by injection. The preparation called blue pill (massa ex hydrar- gyro) is indicated in similar conditions, and is espe- cially beneficial wherever an alterative is called for. In these cases a grain given at bed time, or even a grain in divided portions through the day, will often produce the desired effect. Hence their extensive use in chronic and obscure derangements of the digestive organs, especially of the stomach and liver;—in the whole class of syphilitic affections, glandular enlarge- ments, &c. In like manner all the mercurial preparations men- tioned under the head of Sialagogtjes, become altera- tives by cautious administration in doses more or less minute, and especially when they are given in con- junction with the preparations of sarsaparilla. Pills of Quinia, Opium, $c. R. Calomelanos, gr. vj. Pulveris Opii, gr. iij. Sulphatis Quinia?, gr. xij. Syrupi simplicis, q. s., ut fiat massa et in pilulae xij dividenda. Signa —One night and morning. Dr. Meigs. TONICS. 197 Pills of Blue Mass, Quinia, fyc. R. Massa? ex Hydrargyro, Sulphatis Quinia?, Pulveris Aloes, aa. gr. xij. Syrupi Rhaei aromatici, q. s. ut fiant pilulae xij. Signa.—One three or four times a-day. Either of the above prescriptions will be found use- ful in that condition of the system which supervenes an attack of bilious intermittent or remittent fever. They may be denominated tonic alteratives. Arsenic. Arsenic is a powerful alterative, and one which should be administered with the utmost circumspec- tion. In addition to the formulae already given, the following will be found useful. Pills of Arsenic and Black Pepper. R. Protoxidi arsenici, gr. iv. Piperis nigri, 3ix. Pound these substances in a mortar for a few days at intervals, after which water enough is to be gradually added to form a pill mass, which should be divided into one hundred pills: the French physicians direct double that number, and restrict the patient to one or two pills daily* This preparation of arsenic is regarded in India as an infallible cure for Tuberculous Lepra. Pills of the Arseniate of Iron. R. Proto-arseniatis Ferri, gr. iij. Extracti humuli lupuli, gij. Pulveris althaea?, gss. Syrupi, q. s. ut fiat massa. To be divided into forty-eight pills, of which one is given daily. Recommended !>y Dr. Biett in scrofulous, cancerous, and herpetic diseases. Hydriodale of Arsenic and Mercury. R.. Liquoris hydriodatis arsenici et hydrargyri, gij. Aqua? destillatae, giiiss. Syrupi ziuzibcris, 3*?. 198 TONICS. Misce.—To be taken in four draughts, night and morning. Chiefly given in scrofula and cutaneous eruptions.—Donovan, in Dungli- son, New Remedies, p. 288. MINERAL ACIDS. Nitro-Muriatic Acid. R. Acidi nitrici, gj. ----Muriatici, 3ss. Aqua? destillatae, Svijss. Misce, et adde— Spiritus aetheris nitrici, gijss. Fiat mistura.—Signa.—A tea-spoonful to be given every two hours, in a wine-glass of sweetened water. These acids, in the same proportions, are also em- ployed as a bath in hepatic derangements, and by some are esteemed highly beneficial. To accomplish this end, put a tea-spoonful of the compound acid into a quart of warm water, and apply it to the region of the liver night and morning, by means of a soft sponge. Diluted Nitric Acid. R. Acidi nitrici, gj. Aqua? destillatae, Oij. Sacchari albi, 5j. Fiat mistura.—Signa.—This quantity to be taken daily by the patient. In Lues Venerea. Ferriar, Med. Hist. Mixture of Nitric Acid. R. Acidi nitrici, giss. Pulveris Acacia?, Sacchari albi, aa. 3iij. Aquae destillatae, gvj. Fiat mistura.—Signa.—A table-spoonful pro re nata. Nitric acid may be prescribed as a tonic in the above form, or simply diluted with water. It is best TONICS. 199 taken through a quill, as the teeth suffer when it comes in contact with them. We have seen it arrest the col- liquative sweats of hectic fever when other remedies had failed. Mixture of Nitrous Acid, Laudanum, $c. R. Acidi nitrici, gj. Mistura? Camphorae, gviij. Tincturae Opii, guttas xl. Misce.—Signa.—One fourth part to be taken every three or four hours. This compound is highly recommended by Mr. Thomas Hope, Surgeon, Chatham, in dysentery and cholera.—N. A. Medical and Surgical Journal, Oct. 1826. ( 200 ) CLASS XV. ASTRINGENTS. Doctor Cullen describes astringents to be "such substances as applied to the human body, produce contraction and condensation in the soft solids, and thereby increase their density and force of cohesion." "And by the operation of this corrugating power," adds Dr. Murray, " either directly exerted on a part, or extended by sympathetic action, the morbid affec- tions arising from a state of relaxation are supposed to be removed." In the use of this class of medicines there is one caution suggests itself; namely, that they should not be given to arrest evacuations that are critical, and designed by nature to relieve a plethoric state of the system; unless, however, such evacuation exist to an alarming extent. PILLS, POWDERS, &c. Compound Powder of Alum. R. Aluminis, 9j. Pulveris Kino, gr. v. Misce.—Fiant pulveres, v.—Signa.—One every two hours. In ob- stinate diarrhoea. This compound, though much employed, and praised by some practitioners, contains substances incompati- ASTRINGENTS. 201 ble with each other. It is, nevertheless, very useful in menorrhagia, &c. Powder of Sugar of Lead and Calomel. R. Hydrargyri chloridi mitis, gr. ij vel iv. Acetatis Plumbi, gr. ss ad gr. j. Fiant pulveres iv.—-One every three hours. In Cholera Infantum. The above dose is adapted to any period between ten and twenty months of age. Dr. T. D. Mitchell. Powder with Alum and Opium. R. Aluminis, 3ss. Pulveris Opii, gr. iij. Fiant pulveris vj.—Signa.—One to be taken every three or four hours. In diarrhoea. Powder of Blue Vitriol, fyc. R. Sulphatis Cupri, Boli Armenia?, aa. 5j. Camphorae, gij. Fiat pulvis.—Project 3j. of this powder into a pound of boiling water —filter the solution, and mix gj. of it with gj. of clear water, and apply it to the purulent eyes of infants by means of a syringe, pro re nata.—See Cooper's Surgery. Pills of Acetate of Lead and Calomel. R. Acetatis plumbi, gss. Calomel, gr. v. Conserva? rosarum, q. s. Ut fiant pilula? x. One to be given every two, three, or four hours, according to circumstances. In Hemorrhage, and especially in He- matemesis. Sugar of Lead and Opium. R. Acetatis plumbi, 9j. Gum Opii, gr. j. Misce, et divide in pilulas xij.—A pill to be taken every hour at first, and then every two hours. This is Dr. Graves's prescription for the treatment of Cholera. 26 202 ASTRINGENTS. Pills of Acetate of Lead and Opium. R. Acetatis Plumbi, gr. xij. Pulveris Opii, gr. vj. Conserva? rosarum, q. s., ut fiat massa, in pilulas vi dividenda. One to be taken for a dose, according to circumstances. In haemop- tysis and other hemorrhages. Bolus with Alum and Extract of Bark. R. Aluminis, Extracti Cinchona?, Nucis myristica?, aa. ^ss. Syrupi simplicis, q. s., ut fiat bolus. To be given in uterine and other hemorrhages, and repeated pro re nata. Pills of Alum, Catechu, fyc. R. Aluminis, gr. vj. Extracti Opii, gr. j. Catechu, gr. j. Misce.—To be divided into six pills, one of which is to be given every two, three or four hours. In passive hemorrhage, and in atonic mucous discharges. Pills of Rhatany. R. Extracti Rhatania?, 9j. Pulveris kino, q. s, Ut fiant pilula? viij.—Signa.—A pill to be given every hour or two hours. In the Profluvia. Pills of Creosote. R. Creosoti, gtt. x. Pulveris glycyrrhiza?, gj. Mucilaginis, q. s. Ut fiant xx—Dose—a pill thrice in the day. In Bronchitis, Neural- gia, &c. ASTRINGENTS. 203 Creosote Mixture. R. Creosoti, gtt. xij. Mucilaginis Arabici, giv, Sacchari albi, gj. Fiat mistura.—Dose—a table-spoonful every two or three hours. In Hemorrhages. Alcoholic Solution of Creosote. R. Creosoti, gtt. j. Alcoholis rectificati, gtt. xvj. Misce.—A drop or two of this solution dropped into the cavity of an aching tooth, is said to afford immediate relief. Marinus. Tannin Pills. R. Tannina? pura?, gr. ij. Gummi vel Syrupi, q. s. Ut fiant pilulae viij. One may be given every two or three hours. In Gonorrhoea, &c- Chalk Mixture. R. Cretae praeparatae: 3iss. Sacchari albi, Gummi Arabici, aa. q. s. Aqua? destillata?, 3iv. Olei cinnamomi, gtt. ij. Tincture Opii, gtt. xl vel lx. Misce.—Dose—a table-spoonful every two hours. In Diarrhoea and Dysentery. Another formula for chalk mixture will be given under the head of Absorbents and Antacids. When a strongly astringent chalk mixture is desira- ble, we may add to the above formula Tinct. Kino, 3ij., or the same quantity of Tinctura Rhataniee, or Catechu, or Nut-galls. Camphor, Laudanum and Nitric Acid. R. Aquae camphorae, giv. Acidi nitrici, gtt. iv. Tincturae Opii, gtt. xl vel lx. 204 ASTRINGENTS. Fiat mistura. Dose—a table-spoonful every two hours. In Diarrhrjea and Dysentery. This is the well known and very efficacious prepa- ration called Hope's Mixture. If the nitric acid is added in larger proportion, it is very liable to defeat the object of the prescription. Camphor Water, Lavender, &j-c. R. Aquae camphorae, giv. Tinctura? lavendula? compositae, 3^. Tinctura? Opii, gtt xl vel lx. Fiat mistura. Dose—a table-spoonful every two hours. This prescription is employed in the same cases as the preceding one, and was strongly commended by the late Dr. Parrish. Electuary of Catechu and Opium. R. Electuarii Catechu, gj. Suited to cases of diarrhoea, in tea-spoonful doses. Ten scruples con- tain one grain of opium. Pills of Kino, Opium, fyc. R. Pulveris Kino, gr. xx. -------Opii.gr. ij. Mucilaginis Acacia?, q. s. ut fiant pilula? iv. Of which take one every four hours. In diarrhoea, pyrosis, Sic. Monesia. This substance is the product of a tree which grows in Chili, but its botanical affinities are yet unknown. It is given in the form of Extract, twelve or twenty grains daily, divided into three grain pills. In Leucorrhcea, Diarrhoea, Menorrhagia, &c. &c. ASTRINGENTS. 205 COLLYRIA. These are preparations applied to the eyes; they are sometimes dry, but generally liquid—consisting of in- fusions, decoctions, or distilled waters, with the addi- tion of various substances. Dry Collyrium of Sugar, fyc. R. Sacchari albi, Oxidi Zinci, aa. partes equales. Tere in pulverem. M. Recamier. Dry Collyrium of Mercury, fyc. R. Sacchari albi, gij. Oxidi Hydrargyri rubri, gr. x. Oxidi Zinci impuri praeparati, J)j. Fiat pulvis. M. Dupuytren, Dry Collyrium of Opium, fyc. R. Pulveris Opii, gr. iv. Hydrargyri chloridi mitis, Sacchari purificati, aa. 9j. Tere bene. These compounds are blown into the eyes for the removal of specks on the cornea resulting from inflam- mation. Alum Curd. R. Pulveris Aluminis, gss. Albuminem Ovi, j. Agitate them well until a coagulum be formed.—To be applied on a linen rag to inflamed eyes. It should be removed in three or four hours. Alum Collyrium. R. Pulveris Aluminis, gr. xij vel xx. Aqua? rosarum, 5iv. Fiat solutio.—To be applied to the eye in chronic inflammation 206 ASTRINGENTS, Collyrium of Ioduret of Potassium. R. Aquae rosarum, 5vj. Iodureti potassii, gr. xxiv. Iodini, gr. j vel ij. Fiat collyrium. To be applied to the eyes three or four times in the day. In scrofulous ophthalmia, and ulcerations of the cornea and conjunctiva. Collyrium of Acetate of Zinc. R. Sulphatis Zinci, Acetatis plumbi, aa. gr. vj. Aqua? rosarum, 5iv. Fiat solutio. In this prescription, a double decomposition takes place. Acetate of zinc is held in solution, while sul- phate of lead falls to the bottom. It should be filtered, or used without shaking. Collyrium of Acetate of Lead, &/c. R. Liquoris plumbi acetatis, gtt. xij. Vini Opii, gtt. xl. Aquae rosarum, 5iv. Fiat collyrium. Collyrium of Vinegar, &/c. R. Aceti destillati, 3J- Spiritus Vini diluti, 5ss. Aquae rosarum, gviij. Fiat mistura.—Signa.—To be applied to weak eyes, and in ophthal- mia after depletion. Collyrium of Acetate of Ammonia and Camphor. R. Liquoris Ammonia? acetatis, gij. Mistura? Camphorae, gvj. Misce.—-Signa.—To be applied to eyes requiring a mild astringent and stimulant remedy. ASTRINGENTS. 207 Collyrium of Acetate of Ammonia with Opium. R. Liquoris Ammoniae acetatis, 5ij. Aqua? ferventis, 5vj. Extracti Opii mollis, gr. x. Dissolve the extract of Opium in the hot water—strain, and add the liquor of acetate of ammonia. Useful in acute ophthalmia when considerable pain remains after depletion. Collyrium of Sulphate of Copper. R. Sulphatis Cupri, gr. vj. Camphorae, gj. Aqua? ferventis, gviij. Rub the camphor with the water—then strain, and add the sulphate of copper. This is nearly the same as the formula recommended by Mr. Ware in the treatment of purulent ophthalmia. Collyrium of Corrosive Su blimate. R, Hydrargyri chloridi corrosivi, gr. ij. Aquae destillatae, gviij. Fiat solutio. The above may be advantageously used in gonor- rhceal ophthalmia, as also in that of a scrofulous cha- racter. Collyrium of Opium and Camphor. R. Extracti Opii mollis, gr. x. Camphorae, gr. vj. Aquae ferventis, gxij. Rub the camphor and opium well together in a mortar and add the water. Then strain before using. Collyrium of Poppies, fyc. R. Fomenti papaveris capsularum, giv. Aqua? rosarum, Mistura? Camphora?, aa. gij. 208 ASTRINGENTS. Misce.—Either of the last two coUyria may be employed in the early _ stages of ophthalmia. All of these remedies can be most successfully ap- plied to the eyes by introducing the point of a small syringe into the outer angle, and gradually injecting the collyria. Collyrium of Nitrate of Silver. R. Nitratis Argenti, gr. ij. Aquae destillatae, gij. Fiat solutio.—To be applied at the close of acute ophthalmia, and to promote the absorption of nebulae of the cornea. Emollient Collyrium. R. Radicis Altha?ae officinalis, 3ij- Aquae destillatae, fly. Infuse for^three hours near the fire, and strain.—Employed in inflam- mation of the conjunctiva accompanied with violent irritation. Anodyne Collyrium. R. Colchici autumnalis, 3J. Aqua? Lini bullientis, giv. Tinctura? Opii, 3j- Fiat mistura.—Employed in opthalmia accompanied with great sensi- bility. M. Jadelot. Strichnine Collyrium. R. Strichnia? purae, gr. ij vel iv. Acidi acetici diluti, Aqua? destillatae, aa. ?j. Fiat solutio.—A drop or two, diluted or not according to circumstances, to be applied to the eye several times a-day. Commended by Dr. Ryan in Amaurosis. ASTRINGENTS. 209 INJECTIONS Injections are liquid compositions, containing emol- lient, astringent, or stimulating substances. The parts into which they are thrown are, the external auditory passages, the canal of the urethra, the bladder, and also fistulous cavities, the tunica vaginalis in the case of hydrocele, and the vagina. When employed in the cure of gonorrhoea, two circumstances merit especial attention, viz. the manner of throwing them up, and the frequency of using them. When the common syringe is used, the pipe should be perfectly smooth, short, and conical, so that it cannot pass more than a quarter of an inch into the urethra. The patient should oil the pipe before using it, seat himself on the edge of a chair so as to avoid pressing the perinaeum, draw the penis forward on the syringe with the left hand, and throw up the injection to the seat of disease, (previously ascertained,) with the other. As respects the frequency of injecting, it may be observed, that six or eight times a-day are not too often, and that the cure will be retarded by using these remedies at longer intervals. We cannot forbear remarking, that gonor- rhceal inflammation, situated near the extremity of the penis, can be often cured by a routine plan; but when seated higher up the canal, and affecting Cowper's gland or the prostate, it becomes a serious disease, the cure of which ought not to be undertaken by those ignorant of the structure of the parts and the nature of morbid action. Injection of Pyroligneous Acid for the Ear. R. Acidi pyrolignei, 3\j- Aquae destillatae, 5vj. Fiat injectio.—Signa.—To be injected twice a-day with a silver syringe, in purulent discharge from the meatus auditorius. Buchanan on the Ear. 27 210 ASTRINGENTS. Injection for Catechu for the Ear. R. Extracti Catechu, gr. xij. Aquae bullientis, gvj. Fiat injectio.—To be used four or five times a-day. Idem. Pyroligneous Acid, Ether, fyc.,for the Ear. R. Acidi pyrolignei, Spiritus jEtheris sulphurici, Olei Terebinthinae, aa. partes equales. Misce.—Signa.—Introduce two drops into the meatus auditorius every night, when the cerumen is deficient in quantity.—Idem. Injection of Sulphate of Zinc, fyc. R. Sulphatis Zinci, gr. x. Pulveris Acacia?, 3ij« Tinctura? Opii, 3j. Aquae destillatae, gviij. Fiat injectio.—Used in gonorrhoea virulenta. Injection of Corrosive Sublimate, Sic. R. Sulphatis Zinci, gr. x. Chloridi Hydrargyri corrosivi, gr. ij. Aquae rosarum, gviij. Fiat injectio.—To be used in gleet. This powerful remedy should be employed with great caution. Peruvian Balsam, <$rc.,for the Ear. R. Fellis Bovini, 3iij. Balsami peruviani, 3j. Misce.—Signa.—To be dropped occasionally into the ear to correct a fetid discharge, syringing the ear every day with a weak solution of soap and water. j)r. Hugh Smith. ASTRINGENTS. 211 Injection of Muriate of Ammonia, Sic. R. Muriatis Ammoniae, gr. j vel ij. Chloridi Hydrargyri corrosivi, gr. ij. Aquae destillatae, giv. Fiat injectio.—To be used in chronic gonorrhoea. Injection of Acetate of Zinc. R. Acetatis Zinci, gr. viij. Aquae rosarum, giv. Fiat injectio.—Used in gonorrhoea virulenta. For all these preparations, rose water is an admira- ble menstruum ; it possesses the advantages of being slightly astringent and rendered pure by distillation, and seems therefore particularly applicable to the for- mation of injections and collyria. Injection of Armenian Bole. R. Sulphatis Zinci, 9j. Boli Armenia?, 9ij. Pulveris Acacia?, gij. Aqua? rosarum, § viij. Fiat injectio.—To be used in gonorrhoea. Injection of Calomel, Sic. R. Hydrargyri chloridi mitis, 3J- Gummi Arabici, Tinctura? Opii, aa. gss. Aquae destillatae, 3viij. Fiat injectio.—Signa.—For gonorrhoea or gleet. Injection of Sulphate of Copper. R. Cupri sulphatis, gr. vj. Aquae destillatae, |vj. Tincturae Opii, 3j. Fiat solutio.—Signa.—To be thrown up the urethra in chronic gonor- rhea. 212 ASTRINGENTS. Injection of Tea. R. These viridis foliorum, gj. Aquae ferventis, gvj. Fiat infusio et cola.—To be used as an injection in gonorrhcea viru- lenta. Injection of Ammoniuret of Copper. R. Cupri Ammoniureti, gr. v. Aquae rosarum, 3viij. Fiat solutio.—To be used in chronic gonorrhoea. GARGLES, MOUTH WASHES, &c. Gargles, like injections, are astringent and stimu- lating; to be of any service they must be frequently applied and persevered in for some time. Gargle of Brandy. R. Spiritus vini gallici, Aquae fontanae, aa. partes equales. Brandy and water form an excellent gargle for some cases of inflamed fauces. Gargle of Galls and Alcohol. R. Infusionis gallarum, gvij. Spiritus vini rectificati, \%y Fiat gargarysma.—To be used frequently, in relaxation of the uvula and soft palate. Gargle of Infusion of Oak Bark. R. Corticis Querci falcatae, gj. Aquae fontanae, fbjss- Boil to a pound, and strain ; then add— Sulphatis aluminis, 3ss. Spiritus vini gallici, 3ij. Misce.—To be applied to the uvula when swelled or relaxed, and to be used as an injection in fluor albus. ASTRINGENTS. 213 Gargle of Sulphate of Quinia, fyc. R. Sulphatis Quinia?, gr. xij, -------cupri, gr. xvj. Acidi sulphurici aromatici, 3j. Aquae fontana?, gviij. Fiat mistura.—Signa.—A table-spoonful to be used three or four times a-day, in obstinate sore throat. Dr. Hartshorne. Gargle of Borax, &;c. R. Boratis sodae, 3j. Tincturae myrrhae, gss. Mellis despumati, gj. Aquae rosarum, giv. Fiat gargarysma.—Signa.—To be used as a gargle or mouth wash, in ptyalism or scorbutic affections of the gums. Gargle of Sulphate of Zinc, &/c. !*• Sulphatis Zinci, 3j. Mellis, gss. Tincturae Myrrhae, gj. Spiritus vini gallici, gj. Aquae rosarum, giv. Fiat gargarysma.—To be applied to ulcerated gums, occasioned by excessive salivation. Water can be added if it be too strong. In many cases of mercurial sore mouth, common lead water forms a most soothing and useful applica- tion. It, makes the teeth black—an effect which is only temporary. Dr. Blake's Toothach Solution. R. Aluminis, 3ij> (in pulverem subtillissimum triturandum.) Spiritus aetheris nitrici, 3vij. Fiat solutio.—Said by Dr. Blake, of London, to be an infallible cure for toothach, where this is not connected with rheumatism. Gargle of Alum. R. Sulphatis alumina? et potassae, 3ij. Aquae, 3iv. 214 ASTRINGENTS. Solve.—This is Dr. Cavarra's gargle for foetor oris, or offensive breath. Gargle of Pomegranate. R. Corticis punica? granati, gss. Petalarum rosae rubrae, 3ij. Aquae bullientis, gvj. Fiat infusio.—Cola et adde— Mellis despumati, gj. Aluminis, 3ij. Fiat gargarysma.—Signa.—To be used in inflammations of the throat and fauces. This gargle is highly praised by Dr. Meigs. Muriatic Acid Gargle. R. Infusionis Cinchona?, giv. Mellis despumati, gj. Acidi muriatici, gtt. xviij. Fiat gargarysma.—To be used in chronic inflammation, when pain and swelling have been reduced by depletion—also in cynanche maligna. Ratier's Formulary. Wash of Sulphate of Copper, fyc. R. Sulphatis Cupri, 3ij. Pulveris Cinchona?, gss. Aquae destillatae, giv. Misce.—Signa.—To be used in the gangrenous sore mouth of children; and to be applied to the full extent of the ulceration and excoria- tion. Dr. B. II. Coates. Linctus ivith Muriatic Acid, fyc. R. Acidi Muriatici, 3j. Mellis, Aquae rosarum, aa. gj. Misce.—Signa.—To be applied to scorbutic gums three or four times a-day. Detergent Gargle—Sulphuric Acid, &;c. R. Decocti Hordei, giv. Mellis despumati, gss. Acidi sulphurici, gtt. xx. Fiat gargarysma. Ratier's Formulary. ASTRINGENTS. 215 Mercurial Gargle. '' "" r ' R. Chloridi Hydrargyri corrosivi, gr. ij. Mellis despumati, gss. Aquae destillatae, giv. Fiat solutio.—To be used in venereal sore throat. Idem. Acetous Gargle. R. Acidi acetici, gij. Muriatis Ammoniae, 3j. Mellis, giss. Aquae fontanae, gxij. Fiat gargarysma.—To be used in inflamed fauces. Idem. Astringent Gargle of Acetate of Lead, fyc. R. Acetatis Plumbi, 3ss. Syrupi simplicis, gj. Decocti Hordei, Oj. Fiat solutio.—In mercurial sore mouth, Sic.—Ratier's Formulary. MIXTURES, INFUSIONS, &c. Infusion of Galls. R. Gallae contusae, 3ij. Aquae bullientis, gx. Infuse for four hours, and strain.—Signa.—To be taken in doses of a table-spoonful every hour or two hours. In diarrhoea. It may be rendered more agreeable by the addition of some aromatic. Infusion of Galls and Chalk. R. Infusionis Gallarum, giv. Cretae praeparatae, gss. Tincturae Opii, 3j. Gummi Acacia?, 3j. Fiat mistura.—Dose.—A table-spoonful every two hours. In diar- rhoea. Infusion of Logwood. U. Haematoxyli ligni, £ss. Aqua? bullientis, Oj. 216 ASTRINGENTS. Infuse for two or thee hours, and strain.—Of this a table-spoonful to, be given to children every two or three hours. In cholera and diarrhoea. Mixture of Extract of Logwood, &j-c. R. Extracti Haematoxyli, 3iij' Tincturae catechu, 3ij« Aquae fontanae, 5vij. Misce.—Signa.—Two spoonsful to be given once in three or four hours. In the advanced stages of diarrhoea and dysentery. Mixture with Extract of Bark and Alum. R. Extracti Cinchona?, 5ss. Aluminis, 3ij. Aqua? Cinnamomi, gv. Syrupi Limonis, 5j. Misce.—Signa.—Two spoonsful may be taken every two hours. In low diseases accompanied with hemorrhage. Mixture with Tincture of Catechu, fyc. R. Tincturae Catechu, ?j. ------- Opii, gtt. lx. Pulveris Acacia?, 3ij- Aquae Cinnamomi, 5yj. Misce.—Signa.—A table-spoonful every two hours. In diarrhoea. Solution of Vitriolated Zinc and Alum. As under Emetics. Alum Whey. R. Lactis Vaccinae bullientis, Oj. Pulveris Aluminis, ?ij. Boil them until the coagulum separates, and strain. A cupful to be taken occasionally. In diabetes, &c. Peruvian Bark with Lime Water. R. Pulveris corticis Cinchona?, gss. Aqua? Calcis, gviij. Misce.—Signa.—A table-spoonful to be taken every two hours, or oftener if necessary. In diarrhoea and menorrhagia. ASTRINGENTS. 217 Sirup of Galls, Brandy, <$r. R. Gallarum contusarum, 3>j- Spiritus gallici, gviij. Misce.—Set the brandy on fire and burn out the spirit;—then add— Corticis Cinnamomi, Macis, aa. 3ij> While hot, add sugar by burning it over the inflamed brandy until a sirup is formed.—Decant the pure sirup.—Dose.—A table-spoonful every two hours. In chronic and obstinate diarrhoea. Dr. Parrish. Clyster of Lime Water and Catechu. R. Electuarii Catechu, gss. Aqua? Calcis, gx. Fiat solutio.—Signa.—One-half may be injected at a time; in the diarrhoea of continued fevers. Solution of Sulphate of Copper, &j-c. R. Sulphatis Cupri, gr. iij. Acidi sulphurici, gtt. xx. Aquae destillatae, 3ij. Fiat solutio.—Signa.—From twenty to forty drops to be given every one or two hours in sirup, pro re nata. In menorrhagia. Thatcher's Practice. Enema of Acetate of Lead, $e. R. Acetatis Plumbi, 9j. Tincturae Opii, gtt. lx. Aquae tepidae, gij. Fiat solutio.—Signa.—To be thrown up the rectum in uterine hemor- rhage. Dewees's Syst. of Mid., p. 420. Mixture of Extract of Rhatuny Root, $c. R. Extracti Rhataniae, gj. Syrupi papaveris, Aquae rosarum, aa. gj. Fiat solutio.—Signa.—A tea-spoonful for a dose, pro re nata. In passive hemorrhage and chronic dysentery. M. Fouquier. 28 218 ASTRINGENTS. LINIMENTS, LOTIONS, &c. Lotion of Lime Water, Zinc, 8rc. R. Oxidi Zinci, gr. xij. Cupri sulphatis, gr. iij vel iv. Mellis rosacei, 3j. Aqua? calcis, gij. Fiat lotio.—Recommended as very useful in phagedaenic ulcers of the genitals. Vide Swediaur on Syphilis. Liniment of Lime Water and Linseed Oil. R. Olei Lini, giij. Liquoris Calcis, gvj. Fiat linimentum.—To be applied to burns and scalds by means of a feather or soft rag. Lotion of Lime Water and Alcohol. R. Spiritus vini rectificati, gij. Liquoris Calcis, Oss. Fiat mistura.—To be applied in the same cases as the above. Lotion of Goulard's Extract of Lead, &c. R. Liquoris acetatis plumbi, gj. Spiritus Camphorae, 3iij« Aquae fontanae, Oj. Fiat lotio.—To be used as the former. Chloride of Soda. R. Chloridi Sodas, quantum placet. This compound is much recommended by some of the French surgeons, applied by means of lint in the treatment of old ulcers. Epithem of Acetate of Lead. R. Confectionis rosa?, gj. Mellis, Liquoris plumbi acetatis, Tincturae Opii, aa. Bij. ASTRINGENTS. 219 Misce.—Signa.—To be applied to painful venereal ulcers, and to chancres after the use of lunar caustic. Compound Lotion of Sulphuret of Potash. R. Sulphureti Potassae, gss. Saponis venetae, gj. Spiritus rectificati, giv. Tinctura? Myrrhae, gss. Liquoris Calcis, Oj. Fiat mistura secundum artem.—To be applied to the head night and morning, in cases of tenea capitis. The hair must be shaved pre- vious to its employment. Astringent Fomentation. R. Radicis Bistortae, Corticis Punicae granati, aa. gij. Muriatis Ammoniae, 3ij. Vini rubri, Oj. Misce.—Signa.—To be applied to indolent inflammatory swellings. Ratier's Formulary. Lotion of Bark. R. Cinchona? rubra? contusae, gj. Aquae fontanae, Oj. Boil for ten minutes, strain, then add— Alcoholis camphorati, gviij. This preparation may be used whenever a tonic and stimulant lotion is required. Lotion of Sulphuret of Potassa, fyc. 1. R. Sulphureti Potassae, gj vel ^ij. Aquae, Oj. Misce.— 2. R. Acidi hydrochlorici, gj vel |ij. Aquae destillatae, Oij. Mix one ounce of each lotion with four ounces of warm water, and apply by means of a sponge in cases of psora.—M. Alibert. 220 ASTRINGENTS OINTMENTS. Ointment of Alum, Calomel, fyc, R. Hydrargyri chloridi mitis, 3»j« Sulphatis Aluminis exsiccati, Oxidi plumbi albi, aa. 5ss. Olei Terebinthina?, 3ij« Cerati simplicis, 5iss. Fiat unguentum. This ointment is particularly efficacious in Tinea Capitis. It should be applied every night going to bed, and washed off in the morning ; as soon as the child's head is dry, it should be dusted over with powdered starch, which in the evening is again to give place to the ointment. The hair should be cut off previous to the application of the ointment. Ointment of Gall-nuts. R. Pulveris Gallarum, gj vel ij. Adipis suillae, gj. Fiat unguentum.—Used in hapmorrhoidal affections. Ointment of Oxide of Zinc. R. Oxidi vel florum, 3j- Butyri recentis, gvj. Fiat unguentum.—To be applied to the eyes in cases of defluxions arising from relaxation or slight inflammation of the lids. Ointment of Rhubarb, Opium, &/c. R. Pulveris Rhei, gr. x. ------- Opii, gr. v. Cerati simplicis, giss. Fiat unguentum.—This ointment has been found very efficacious in indolent ulcers. Ointment of Tar, S,-c. R. Unguenti picis liquidae, gj. --------hydrargyri nitratis vel cilrini, gss. Fiat mistura.—In tinea capitis. ASTRINGENTS. 221 Ointment of Tar and Opium. R. Pulveris Opii, gij. Unguenti picis, gj. Fiat unguentum.—Signa.—Haemorrhoidal ointment. This compound has been found very efficacious in hsemorrhois. Kirkland's Neutral Cerate. R. Emplastri plumbi, 3iv. Olei olivarum, Creta? praeparatae, Acidi acetici, aa. 5ij. Super-acetatis plumbi, 3JSS- The plaster and oil are first to be melted over a gentle fire. The prepared chalk is then to be briskly stirred in, and when the mix- ture is sufficiently cooled, the vinegar and superacetale of lead are to be added, and the whole stirred until nearly cold. This cerate, which is not to be met with in the phar- macopoeia, is strongly recommended in abraded irrita- ble surfaces, and the latter stages of burns. Aromatic Sulphur Ointment. R. Potassae carbonatis, 5ss. Aqua? rosae, ?j. Hydrargyri sulphureti rubri, 5j Olei essentialis Bergamota? 5ss. Sulphuris sublimati et loti, Adipis suilli, aa. gx. Misce secundum artem.—Employed in scabies. Baleman's Synopsis. ( 222 ) CLASS XVI. ABSORBENTS OR ANTACIDS. Absorbents or Antacids form a class of remedies for correcting acidity in the stomach and bowels. As a general rule they should be preceded by an emetic or cathartic, or both. When a permanent effect is de- sired, they are usually combined with tonics, aroma- tics, and sometimes narcotics. When given alone, they too frequently afford but transient relief. POWDERS. Compound Cretaceous Powder with Opium* R. Cretae praeparatae, 3iss. Pulveris Cinnamomi, 3J. ------ Piperis longi, gr. viij. -------Opii, gr. vj. Fiat pulvis.—Divide in chartulas xij.—One three or four times a-day. In diarrhoea. The above formula, with a slight alteration, is from the London Pharmacopoeia. Powder with Crabs' Claws and Rhubarb. R. Chelae cancrorum, gj. Pulveris Rhei, 9ij. ABSORBENTS OR ANTACIDS. 223 Misce, et divide in pulveres iv.—Of which one may be taken once or twice a-day, according to circumstances. In acidity of the Pri- mae viae. This preparation is called by the several names of crabs' claws, eyes, and stones. It is a carbonate of lime united ■, with some animal gelatine, and which, like prepared oyster shells, has little or no superiority over the prepared chalk. Powder with Magnesia, Fennel Seeds, fyc. R. Magnesia?, gss. Pulveris seminum Fceniculi, ------ Cinnamomi, aa. gj. Fiat pulvis.—Dose.—A small tea-spoonful three or four times a-day. Powder with Soda, Magnesia, fyc. R. Magnesiae calcinatae, gss. Bi-carbonatis Sodae, Pulveris Zingiberis, aa. 9j. Misce.—Signa.—A small tea-spoonful occasionally. In cardialgia. Powder with Magnesia and Colombo. R. Magnesiae ustae, 3jss. Pulveris Colomba?, 3j. Misce.—Divide in chartulas vj.—Of which one maybe taken three times a-day, in sugar and water. In Cardialgia. PILLS. Pills of Soda, Rhubarb, $c. R. Pulveris Rhei, Carbonatis Soda? exsiccatae, Extracti Gentianae, aa. 9j. Hydrargyri chloridi mitis, gr. iij. Misce.—Fiant pilulae xx.—Signa.—Two occasionally. In dyspepsia, 224 ABSORBENTS OR ANTACIDS, MIXTURES, SOLUTIONS, &c. Chalk Mixture. R. Cretae praeparatae, 3iij. Sacchari albi, Pulveris gummi Acaciae, aa. 3iss. Aquae Menthae, gvj. Fiat mistura.—Signa.—A table-spoonful for a dose every two hours. When administered in Diarrhoea, Astringents are added. Solution of Salt of Tartar. R. Carbonatis Potassae, gj. Sacchari albi, ?j. Tincturae Lavandula? compositee, 31J. --------Opii, gtt. xl. Aquae Menthae, ^iv. Misce.—Signa.—A table-spoonful every hour or two hours. In sick- ness of the stomach occasioned by acidity. The opium in the above prescriptions may be omit- ted at the discretion of the practitioner. Mixture of Salt of Tartar, Ammonia, $c. R. Spiritus Ammonia?, Carbonatis Potassae, aa. 3ij. Aquae Cinnamomi, giv. Misce.—Signa.—A large tea-spoonful for a dose pro re nata. In Pyrosis. Lime Water and Milk. R. Aqua? calcis, Lactis recentis, aa. giij. Misce.—Signa.—Two table-spoonsful for a dose. In sickness of the stomach few remedies are more prompt in their effect. An antacid remedy admirably adapted to children, is prepared by pouring four ounces of boiling water on a heaped tea-spoonful of calcined mag- nesia, and giving a dessert-spoonful of the clear solution every hour or two. It is slightly aperient. ABSORBENTS OR ANTACIDS. 225 Mixture with Ammonia, Magnesia, 8rc. R. Magnesia? ustae, 3j. Aquae Ammonia?, 2j. Spiritus Cinnamomi, 3hj- Aquae destillatae, gvss. Misce.—Signa.—A table-spoonful every two hours. Usually given in the sickness accompanying pregnancy. Mixture of Magnesia, Camphor, &/c. R. Magnesiae alba?, 3j. Camphorae, gss. Sacchari albi, Gummi Acacia?, aa. gij. iEtheris sulphurici, 5ss. Aqua? destillatae, 5iv. Misce.—Signa.—A table-spoonful for a dose four or five times a-day. In flatulency and irritable stomach.—Dr. E. Griffiths. Dyspeptic Lie. Take of Hickory Ashes ----- 1 quart, Soot ------ 6 ounces, Boiling Water ----- 1 gallon. Mix and let them stand for twenty-four hours, frequently stirring the ingredients. A tea-cupful may be given of this liquor, (decanted,) three times a-day. It should be decanted always at the end of twenty-four hours, for by standing on the materials a long time the water acquires almost caustic properties, and may do serious in- jury. This domestic remedy we have thought best to couch in the English language. It deserves an inser- tion from the circumstance that it was employed by Dr. Physick in his own case, and we are informed was of decided advantage when the usual alkaline remedies had failed. 29 226 ABSORBENTS OR ANTACIDS. Solution of Salt of Tartar, Sj-c R. Carbonatis Potassae, gj. Pulveris gummi Acacia?, 3ss. Olei Mentha? sativae, gtt. ij. Tincturae Opii, gtt. x. Aquae aeratae, ^iij. Fiat solutio.—Signa.—A table-spoonful for a dose, pro re nata. In sickness of the stomach.—Dr. Meigs. Mixture of Colombo, &;c. R. Radicis Colombae, gss. Coque in aqua, ^iij ad Zv. Cola et adde— Carbonatis Potassae, 9ss. Succi limonis, giij. Tinctura? Opii, gtt. xij. Misce.—Signa.—From a tea to a table-spoonful may be given every hour. This mixture is said to be powerfully anti-emetic; and is much praised by Dr. Meigs. Anti-Emetic Mixture. R. Tinctura? corticis Aurantii, ?ss. --------Aloes socotrinae, --------Castorei, aa. 3j. Misce.—Signa.—The dose may be from forty to fifty drops, three or four times a-day. In chronic vomiting, occasioned by atony or spasm of the stomach, the above is strongly recommended in Hufeland's Treatise on Scrofula. ABSORBENTS OR ANTACIDS. 227 Mixture with Carbonate of Soda, &/c. R. Sodae carbonatis, 9iv. Infusionis Gentianae compositae, Aquae cinnamomi, al. giij. Tincturae Cardamomi, gss. Fiat mistura.—Signa.—A table-spoonful every two or three hours. In acidity and flatulency of the stomach, &c. ( 228 ) APPENDIX, NO. I. DIETETIC PREPARATIONS. The importance of an acquaintance with those pre- parations of diet peculiarly designed for the patient during disease and convalescence, is so obvious that it requires little or no comment. It was remarked by Dr. Rush, in his lectures, that a physician should spend six months in a kitchen before entering upon his practical career. As the medical attendant, there- fore, is called upon frequently to give directions and rules for preparing the diet for the sick, we have in- serted a few formulas for those articles which are in daily use. However apparently trifling such a class may appear to some persons, the physician will find that an attention to it will place the patient more completely under his own control, and inspire con- fidence in the relations and attendants. The rules to be observed in giving nourishment to the sick, will generally, present themselves; but there is one in par- ticular which should not be overlooked. In all low diseases, the nurse should be directed never to give too much at once, but frequently to repeat a small pro- portion. The lapse of a very short time without food, will frequently in cases of great prostration, reduce the patient very low, and may endanger his life. This rule is not intended to be applied to those DIETETIC preparations. 229 chronic derangements of the digestive functions, which are to be remedied principally by a regulation of diet, and in which, the old adage, " a little and often," has too frequently, we are convinced, been perniciously advised. Decoction of Barley; or, Barley Water. Take of Pearl Barley, - - - - - 2 ounces, Boiling Water, - - - - - 2 quarts. Before adding the boiling water, let the barley be well washed. Then boil it to one-half, and strain the liquor. A little lemon juice and sugar may be added, if desirable. To be taken ad libitum in in- flammatory diseases. Rice Water. Take of Rice, - - - - - - 3 ounces, Let it be well washed, and add to it— Water, - - - - - - 2 quarts. Boil it for an hour and a half, and then add sugar and nutmeg as much as may be required. To be taken ad libitum. Rice, when boiled for a considerable time, assumes a gelatinous form, and is a very excellent diet, mixed with milk, for children. It is believed by many per- sons to have a constipating property. This opinion, however, appears to be destitute of foundation. Infusion of Flaxseed. As under Expectorants. Mucilage of Gum Arabic. As under Expectorants. Decoction of Bran. Take of Wheat Bran, recent, - - - 1 pint, Water,......3 quarts. 230 dietetic preparations. Boil down one-third, strain off the liquor, and add sugar, honey or molasses, according to the taste of the patient. Bran tea may be made by using boiling water, and suffering the mixture to stand in a covered vessel for three or four hours. Sage Tea. Take of The dried leaves of sage, - - half an ounce, Boiling Water, - - - 1 quart. Intuse for half an hour, and then strain. Sugar and lemon juice may be added in the proportion required by the patient. In the same manner may be made balm and other teas. These infusions form very agreeable and useful drinks in fever, and their diaphoretic powers may be increased by the addition of sweet spirits of nitre; or, what is better, by antimonial wine. Infusion of Malt. Take of Ground Malt, - - - - - 1 pint, Scalding Water,* - - - - - 3 pints. Infuse for two hours, and strain off the liquor, to which may be added sugar or lemon juice, if required. This is a favourite preparation with Dr. Parrish, and employed by him in inflammatory fevers. Lemonade. Take of Fresh Lemon Juice, - Fresh and very thin peel of Lemon, White Sugar, Boiling Water, - 4 ounces, - half an ounce, - 4 ounces, - 3 pints. * Water not quite brought to the boiling point. DIETETIC PREPARATIONS. 231 Let them stand until cold, then strain off for use. When employed in fevers, a little nitrate of potash or sweet spirits of nitre may be added. This preparation, when freely taken by the patient, sometimes produces pain in the bowels. It must therefore be given with some reserve as a daily drink. Water Gruel. Take of Oatmeal, - - - - - -2 ounces, Water, - - - - - - 1 quart. Boil for ten or fifteen minutes, and strain, adding sugar and salt to make it agreeable. Milk for Infants. Take of Cow's Milk, - - - - - 1 part, Water, - - - - - -2 parts. Loaf Sugar as much as may be agreeable. It is necessary, when children are to be raised by the hand, to dilute the milk. These proportions may be altered as the child advances in age. The ob- ject is to make a diet as near the qualities of the ma- ternal milk as possible. Rice Gruel. Take of Ground Rice, - - - - - 1 ounce, Cinnamon, - - - - - 1 drachm, Water, - . - - - - 1 quart. Boil for forty minutes, adding the aromatic near the conclusion. Strain and sweeten it. Wine may be added if neeessary. Panado. Take of Wheat Bread, - - - - - 1 ounce, Cinnamon, - - - - - 1 drachm, Water, - - - - - - 1 pint. 232 DIATETIC PREPARATIONS. Boil them until well mixed, then add a little grated nutmeg and sugar. Wine or butter may also be added if desirable. Compound Salep Powders. R. Salep, Gummi Tragacanthi, Sago, aa. giv. Cochineal, gss. Testae ostrearum preparatae, gj. To be carefully mixed and divided into powders of 3j each. Stir one of these powders into a pint of milk, and boil them together for ten or fifteen minutes. To be drank freely in dysentery and diarrhoea. These are the dysenteric powders of Dr. Castanello. A somewhat analogous preparation which bears the same name, is prepared as follows: R. Pulveris gummi arabici, Gummi Tragacanthi, Marantae, Sago, Tapioca?, aa. 3ij. Mix them well together, and boil in a pint of milk, flavoured with nutmeg or cinnamon. To be used as a diet in dysentery, diar- rhoea, Sic. Sic. Sago. Take of Sago, ----- 2 spoonsful, Water, ----- l pint. Boil gently until it thickens, frequently stirring. Wine, sugar, and nutmeg, may be added according to circumstances. Tapioca Jelly. Take of Tapioca,.......2 spoonsful, Water,.......1 pint. Boil it gently for an hour, or until it assume a jelly-like appearance. Add sugar, wine, and nutmeg, with lemon juice, to suit the taste of the patient and the nature of the case. DIETETIC PREPARATIONS. 233 Arrow Root. Take of Arrow Root,.....1 table-spoonful, Sweet Milk,.....half a pint, Boiling Water,.....half a pint. Boil them a few moments over the fire. Sweetened with loaf sugar it is one of the best ali- ments for children, and more especially when their bowels are irritated. Boiled Flour. Take of Fine Flour,.......a pound. Tie it up in a linen cloth as tight as possible, and after frequently dip- ping it in cold water, dredge the outside with flour till a crust is formed round it, which will prevent the water soaking into it while boiling. It is then boiled until it becomes a hard, dry mass. Two or three spoonsful of this may be grated and prepared in the same manner as arrow root, for which it forms an excellent substitute, and can be obtained in the country, when perhaps the other cannot. Vegetable Soup. Take one turnip, one potato, one onion. Let them be sliced, and boiled in one quart of water for an hour. Add as much salt as is agreeable, and pour the whole upon a piece of dry toast. This preparation forms an agreeable substitute for animal food, and may be given when the former is in- admissible. Chocolate. When this is desired by the patient, it should be suffered to stand until cold, after having been made in the usual way. The oily parts thus collect on the surface and should be taken off. The liquid may then be boiled again, and sugar, bridge. IV. The Hand, its mechanism and vital endowments as evincing design, with numerous wood cuts. By Sir Charles Bell, K. H. F. R. S. V. Chemistry, Meteorology, and the Function of Digestion, considered with reference to Natural Theology. By Wm. Protjt, M. D, F. P.. S. VI. The History, Habits, and. Instincts of Animals. By the Rev. Wm. Kirby, M. A.. F. R. S., Illustrated by numerous engravings on copper. VII /Vnimal and Vegetable Physiology, considered with reference to Natural Theology. By Peter Mark Rojbt, M. D. Illustrated with nearly 500 wood cuts. VIII. Geoloo-y and Mineralogy considered with reference to Natural Theology. By the Rev Wm. Buckland, D. D, Canon of Christ Church, and Reader m Geology and Mineralogy in the University of Oxford. With e.ghty-nine copper-plates and large coloured maps. 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