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'■--,•■• 'J.:•■>"**- ■<• v:,.—' i"*^- 'V'^^^t^;.;-'^-* ■rV: '•'"'•:"-' v- ^ w>- ■■■»*" '• ^<^%---vV.' >i^'-^-'^v?'^'^ m 3 SURGEON GENERAL'S OFFICE !; WBRA1Y ANMEX 'ectio \ ^ _^^. PHYSIOLOGY OF DIGESTION CONSIDERED WITH RELATION TO THE PRINCIPLES OF DIETETICS. BY ANDREW COMBE, M.D. FELLOW or THE ROYAL COLLEOE OF PHYSICIANS OF EDINBURGH j rHYIICIAIf EXTRAORDINARY TO THE O.UEEN IN SCOTLAND, AND CONSULTING PHYSICIAN TO THE KINO AND QUEEN OF THE BELGIANS. " Nor is it left arbitrary, at the will and pleasure of every man, to do as he list; after the dictates of a depraved humour and extrava- fant phancy, to live at what rate he pleaseth ; but every one is ound to observe the Injunctions and Law of Nature, upon the pe- nalty of forfeiting their health, strength, and liberty—the true and long enjoyment of themselves."—Mainwatringe. FRO* THE THIRD EDINBURGH REVISED AND ENLARGE* EDITIOW. ^»B^v^ WITH ILLUSTRATIONS. iw**V XEW YORK: ' ^----- | WILLIAM H. COLYEr/^RAY No. 5 Hague-street. BOSTON: LEWIS & SAMPSON, 1844. ArtT^ wx ADVERTISEMENT TO THE THIRD EDITION. The first edition of the present volume consisted of two thousand copies, and was exhausted in little more than five months. The second extended to the very unusual number of four thousand copies, and has now been for some weeks out of print. In the United States the work has also been twice republished. This success is very gratifying, and affords a very encouraging indication that the importance of physiolo- gical knowledge as a branch of general instruction is every day becoming better understood and more extensively recognised. In the edition now in the hands of the reader various im- provements have been effected. Of these the most important has been the introduction of a new chapter, explaining more fully the relation subsisting between the different kinds of food and the principal varieties of the human constitution. Several other improvements, of a still more extensive kind, had also occurred to me, but long-continued indisposition has prevented me from carrying them into effect. In this uncer- tainty, it seemed to me bette.r rather to reprint the work with such alterations as I was able to make on it, than to defer its appearance for an indefinite time ; and 1 trust that most of my readers will concur in thinking that in this I have decided correctly. With these apologetic remarks, 1 must now leave the work, with all its remaining imperfections, to the kind indulgence of the public. Edinburgh, 25 Rutland-street, October 15,1841. PREFACE. The present volume is essentially a continuation of tire work of which the tenth edition has lately appeared, under the ■title of " The Principles of Physiology applied to the Preser- vation of Health and to the Improvement of Physical and Mental Education ;" and its object is the same—namely, to lay before the public a plain and intelligible description of the structure and usesof some of the more important organs of the human body, and to show how information of this kind may be usefully applied, not only in the prevention of suffering, but in improving the physical, moral, and intellectual condition of man. At first sight it may seem doubtful to many of my readers whether I have not exceeded proper bounds in dedicating a whole volume to the consideration of the single subject of Digestion ; but the more we consider the real complication of the function, the extensive influence which its varying states exercise at every period of life over the whole of the bodily organization, and, consequently, over our moral and intellectual nature, and the degree to which its morbid de- rangements undermine health, happiness, and social useful- ness, we shall become more and more convinced of the deep practical interest which attaches to a familiar acquaintance with the laws by which it is regulated, and of the necessity of entering into their examination at sufficient length to ensure the ready applicability of our knowledge in our general con- duct. In infancy errors in diet and derangement of the digestive organs are admitted to be among the principal causes of the striking mortality which occurs in that period of life. In youth and maturity the same influence is recognised, not only in the numerous forms of disease directly traceable to that origin, but also in the universal practice of referring every obscure or anomalous disorder to derangement of the stomach or bowels. Hence, too, the interest which has always beer- felt by the public in the perusal of books on Dietetics and Indigestion ; and hence the prevailing custom of using purga- tives as remedies for every disorder, very often with good, but not unfrequently with most injurious effects. Numerous and popular, however, as writings on Dietetics bave been, and excellent as are many of the precepts which have been handed down by them from the earliest ages, sanc- tioned by the warm approval of every successive generation, ,JT PREFACE. it is singular how very trifling their influence has been, and continues to be, in altering the hahits of those to whom they are addressed. In a general way, we all acknowledge that diet is a powerful agent in modifying the animal economy ; yet, from our conduct, it might justly be inferred, that we either regarded it as totally devoid of influence, or remained in utter ignorance of its mode of operation, being left to the guidance of chance alone, or of notions picked up at random, often at variance with reason, and, it may be, in contradiction even with our own daily experience. In thus attempting to direct public attention to the more careful consideration of a subject which he conceives to be deeply interesting to their welfare, the Author does not enter- tain the hope that his work will immediately produce any perceptible change in .the general practices of society, or that he will so far shake the force of habit as to induce many healthy men of mature age to forsake their accustomed regi- men merely because it is at variance with the laws of Nature. But he is, nevertheless, willing to believe that, among valetu- dinarians and the young of both sexes,, whose habits are not formed, and numbers of whom err as much from ignorance as from the force of passion, many may be found who will be glad to obtain the guidance of knowledge and principle in the regulation of their mode of life ; and that even many parents, who may not have resolution enough to forsake mischievous indulgences to which they have long been accustomed, may, nevertheless, be anxious to avail themselves of any assistance on which they can depend for the better bringing up of their children. If in these expectations he is not too sanguine, the future advantage to the race from the present diffusion of dietetic knowledge is as certain, and almost as encouraging, as if its effects were instantaneous on both old and young. . In the march of human improvement, months and years count but as moments. The men of to-day will soon have acted their parts, and given place to those who are now with youth- ful energy adding to their knowledge, and throwing off a portion of the prejudices of their fathers. They in their turn will speedily be succeeded by their children, and the appa- rently speculative but really practical discoveries of the one generation will thus become the established and influential truths of the next. In this way every individual change in the habits of society may be so slow and minute as at the moment to escape our notice, but it is not on that account the less real. Nobody who compares the coarse feeding and riotous convi- vialities of our forefathers, at the beginning of last century, with the more refined and temperate habits of the present day, will think of denying that a prodigious step has been made in the interval even with respect to eating and drinking, pro- cesses so often considered as beyond the influence of reason. PREFACE. V And yet, if we were required to point out any single year of the whole century during which a marked reformation took place, we should not be able to do so. This being the case, then, can we, their descendants, maintain that we are arrived so nearly at perfection as to leave no room for corresponding improvement in our day, however slow it may also be ? My conviction is so much the reverse, that it seems to me certain that our onward progress will continue through generations yet unborn, with the same steadiness as it has done through generations long since gathered to their fathers ; and that every attempt made to render man better acquainted with the Jaws of his own constitution, and thereby provide him with fixed and better principles of action, will exert a positive and decided influence on the progress of the race, proportioned in extent to the truth, clearness, and general applicability of the views which are unfolded. On such considerations do I ground my hope that the present volume, notwithstanding its nume- rous defects, will (in so far as it really imbodies truths of practical importance) contribute in its own limited sphere to the general end. The real cause of the little regard paid to dietetic rules— and it is of consequence to remark it—is not so much indiffe- rence to their influence, or even the absolute want of valuable information, as the faulty manner in which the subject is usual- ly considered. In many of our best works the relation subsist- ing between the human body on the one hand, and the qualities of alimentary substances on the other, is altogether lost sight of, although it is the only solid principle on which their proper adaptation to each other can be based. In this manner, while the attention is carefully directed to the consideration of the abstract qualities of the different kinds of aliment, little or no regard is paid to the relation in which they stand to the indi- vidual constitution, as modified by age, sex, season, and cir- cumstances, or to the observance of the fundamental laws of digestion. And hence, although these conditions are not un- frequently of much greater importance to the general health than -even the right selection of food, yet, when indigestion arises from neglecting them, the food alone is blamed, and erroneous conclusions aro drawn, by relying on which, upon future occasions, we may easily be led into still more serious mistakes. It is, indeed, from being left in this way without any guid- ing principle to direct their experience,, and test the accuracy of the precepts laid down to thein for the regulation of their conduct, that many persons begin by being bewildered by the numerous discrepancies which they met with between facts and doctrine, between counsel and experience—and end by becoming entirely skeptical on the subject of all dietetic rules • 1* *I PREFACE. whatever, and regarding them as mere theoretical effusions, based on fancy, and undeserving of a moment's consideration. The true remedy for this state of things is, not to turn away in disgust and despair, but to resort to a more rational mode of inquiry—certain that, in proportion as we advance, some useful result will reward our labours. Such, accordingly, has been my aim in the present publication , and if I shall be found to have been even moderately successful in attaining it, I shall rejoice in the confident conviction that others will be led to still more positive and beneficial results. Utility has been my great object throughout. In following what I conceive to be an improved mode of investigation, I have in some instances placed known facts in a new point of view, and deduced from them practical inferences of considerable value and easy ap- plication : but beyond this I am not ambitious of originality ; and if I have anywhere used expressions which may seem to do injustice to others, it has been entirely without any such design, and, consequently, I will be prompt to acknowledge my error and rectify the involuntary mistake. In the previous editions of this volume I stated that I had derived the utmost advantage from a very valuable work by Dr. Beaumont, an American writer, which—though faulty in its arrangement, and necessarily defective in many essential particulars—contains an authentic record of some of the most curious and instructive observations which have ever been made on the process of digestion. That excellent and en- lightened physiologist had the rare good fortune to meet with a case where an artificial opening into the stomach existed, through which he could see everything that took place during the progress of healthy digestion ; and, with the most disin- terested zeal and admirable perseverance, he proceeded to avail himself of the opportunity thus afforded of advancing human knowledgs, by engaging the patient, at a heavy expense, to live with him for several years, and become the subject of numerous and carefully conducted experiments. Having, through the kindness of a friend resident in the United States, been early favoured with a copy of the original work, I felt so strong a conviction of the superior value of investigations con- ducted under circumstances so unusually free from the many sources of fallacy inseparable from experiments on animals, that at llie time I had almost resolved to reprint it entire, both as an act of justice to Dr. Beaumont, and as a valuable con- tribution to physiological science. In the belief, however, that a republication would immediately appear from some other quarter, I abstained from doing so, and contented myself with making free use of such parts of it as seemed most calculated to throw light upon the practical questions which I was en- gaged in discussing. But after waiting in vain for two years. PREFACE. Til and finding the interest excited in Dr. Beaumont's experiments increased in proportion as their nature and value became more extensively known by means of the extracts given in the pre- sent volume, I felt it due to Dr. Beaumont to delay no longer, and accordingly republished his work with the addition of various explanatory and practical notes,* and the high favour with which it has been welcomed by the leading medical jour- nals shows that I did not exaggerate its importance. Dr. Beaumont's work being thus rendered accessible to the English reader, I was anxious, ii) the present edition, to omit as much of the matter formerly extracted from it as I possibly could. But, on making the attempt, I found the extracts every- where so mixed up with the practical conclusions which they were used to enforce, that I could not leave them out without materially weakening the argument. I have, therefore, retain- ed them ; and an additional reason for doing so was, that Dr. Beaumont's volume is in the hands almost exclusively of pro- fessional men, and is thus likely to remain almost as little known to the general reader as if it were still confined in circulation to the other side of the Atlantic. Objections may be stated to several of the repetitions which occur in the following pages. The only apology I have to offer for them is, that I committed them deliberately, because they seemed to me necessary to ensure clearness, and because the intimate manner in which the different functions are connected with each other sometimes made it impqssible to explain one without again referring to the rest. My prime objects being to render the meaning unequivocally plain, and impress the subject deeply upon the reader's mind, I thought it better to risk in this way the occasional repetition of an important truth, than to leave it in danger of being vaguely apprehended or its true value unperceived. For these reasons, it is hoped that the fault—if such it is—will be leniently overlooked. * Experiments and Observations on the Gastric Juice and the Physiology of Digestion, by William Beaumont, M.D., of the United States Army. Reprinted with Notes by Andrew Combe, M.D 1 vol. post 8vo Edinburgh, 183S CONTENTS. PART I. PHYSIOLOGY OF DIGESTION. CHAPTER I. GENERAL VIEW OF THE OBJECTS AND LAWS OF NUTRITION. Waste or loss of substance always attendant on action—In the ve- getable and animal kingdoms waste is greater than in the phy- sical—Living bodies are distinguished by possessing the power of repairing waste—Vegetables, being rooted in one place, are always in connexion with their food—Animals, being obliged to wander, receive their food at intervals into a stomach—Nutrition most active when growth and waste are greatest—In vegetables the same causes which increase these processes also stimulate nutrition—But animals require a monitor to warn them when food is needed—The sense of Appetite answers this purpose— The possession of a stomach implies a sense of Appetite to regu- late the supplies of food. 25-31 CHAPTER II. THE APPETITES OF HUNGER AND THIRST. Hunger and Thirst, what they are—Generally referred to the stomach and throat, but perceived by the brain—Proofs and illus- trations—Exciting causes of hunger—Common theories unsatis factory—Hunger sympathetic of the state of the body as well as of the stomach—Uses of appetite—Relation between waste and appetite—Its practical importance—Consequences of overlooking it illustrated by analogy of the whole animal kingdom—Disease from acting in opposition to this relation—Effect of exercise on appetite explained—Diseased appetite—Thirst—Seat of Thirst— Circumstances in which it is most felt—Extraordinary effects of injection of water into the veins in cholera—Uses of thirst, and rules for gratifying it. 31-51 CHAPTER III. MASTICATION, INSALIVATION, AND DEGLUTITION. Mastication—The teeth—Teeth, being adapted to the kind of food, vary at different ages and in different animals—Teeth classed and described—Vitality of teeth, and it3 advantages—Causes of disease in teeth—Means of protection—Insalivation, and its uses —Gratification of taste in mastication—Deglutition. 51-63 CHAPTER IV. ORGANS OF DIGESTION--THE STOMACH—THE GASTRIC JUICE. Surprising power of digestion—Variety of sources of food—All structures, however different, formed from the same blood—Ge- neral view of digestion, chymification, chylification, sanguifica- tion, nutrition—The stomach in polypes, in quadrupeds, and in man—Its position, size, and complexity in different animals—Its structure ; its peritoneal, muscular, and villous coats ; and uses of each—Its.nerves and bloodvessels ; their nature, origins, and uses—The former the medium of communication between the brain and stomach—Their relation to undigested food—Animals K CONTEXTS. not conscious of what goes on in the stomach—Advantages of thit arrangement—The gastric juice the grand agent in digestion- Its origin and nature—Singular case of gunshot wound making a permanent opening into the stomach—Instructive experiments made by Dr. Beaumont—Important results. 63-99 CHAPTER V. THEORY AND LAWS OF DIGESTION. Different theories of Digestion—Concoction—Fermentation—Putre- faction—Trituration—Chemical solution—Conditions or laws of digestion^Influence of gastric juice—Experiments illustrative of its solvent power—Its mode of action on different kinds of aliment; beef, milk, eggs, soups, &c.—Influence of temperature—Heat of about 100° essential to digestion—Gentle and continued agitation necessary—Action of stomach in admitting food—Uses of its muscular motion—Gastric juice acts not only on the surface of the mass, but on every particle which it touches—Digestibility of different kinds of food—Table of results—Animal food most di- gestible—Farinaceous next—Vegetables and soups least digestible —Organs of digestion simple in proportion to concentration of nutriment—Digestibility depends on adaptation of food to gastric juice more than an analogy of composition—Illustrations—No increase of temperature during digestion—Dr. Beaumont's sum- mary of inferences. 99-129 . CHAPTER VI. CHYLIFICATION, AND THE ORGANS CONCERNED IN IT. Chyliflcation—Not well known—Organs concerned in it—The intestinal canal—Its general structure—Peritoneal coat—Mesen- tery—Muscular coat—Uses of these—Air in intestines—Uses of —Mucous coat—Analogous to skin—The seat of excretion and absorption—Mucous glands—Absorbent vessels—Course of chyle toward the heart—Nerves of mucous coat—Action of bowels ex- plained—Individual structure of intestines—The duodenum; jeju- num" ; and ileum—Liver and pancreas concerned in chyliflcation —Their situation and uses—Bile, its origin and uses—The pan- creas—Its juice—The jejumim described-t-The ileum ; coacum ; colon ; and rectum—Peristaltic motion of bowels—Aids to it— Digestion of vegetables begins in stomach, but often finished in the bowels—Illustration from the horse—Confirmation by Dupuy- tren. 129-152 PART II. THE PRINCIPLES OF DIETETICS VIEWED IN RELATION TO THE LAWS OF DIGESTION. CHAPTER I. TIMES OF EATING. The selection of food only one element in sound digestion__O.Lat conditions essential— Times of eating—No stated hours for eat- ing—Five or six hours of interval between meals generally suffi- CONTENTS. xJ clent; but must vary according to circumstances—Habit ha* much influence—Proper time for breakfast depends on constitu- tion, health, and mode of life—Interval required between break- fast and dinner ; best time for dinner ; circumstances in which lunch is proper ; late dinners considered ; their propriety depen- dant on mode of life—Tea and coffee as a third meal; useful in certain circumstances—Supper considered—General rule as to meals—Nature admits of variety ; illustrations ; but requires the observance of principle in our rules. 153-175 CHAPTER II. ON THE PROPER QUANTITY OF FOOD. Quantity to be proportioned to the wants of the system—Appetite indicates these—Cautions in trusting to appetite—General error in eating too much—Illustrations from Beaumont, Caldwell, Head, and Abercrombie—Mixtures of food hurtful chiefly as tempting to excess in quantity—Examples of disease from excess in servant-girls from the country, dressmakers, &c.—Mischief from excessive feeding in infancy—Rules for preventing this— Remarks on the consequences of excess in grown persons— Causes of confined bowels explained—And necessity of fulfilling the laws which God has appointed for the regulation of the animal economy inculcated. 175-196 CHAPTER III. CONDITIONS TO BE OBSERVED BEFORE AND AFTER EATING. General laws of organic activity apply to the stomach as well as to other parts—Increased flow of blood toward the stomach during digestion—Hence less circulating in other organs—And, con- sequently, less aptitude for exertion in them—Bodily rest and mental tranquillity essential to sound digestion—Rest always attended to before feeding horses—Hence also a natural aversion to exertion immediately after eating—Mischief done by hurry- ing away to business after meals—Severe thinking hurtful at that time—Playful cheerfulness after dinner conducive to di- gestion—The mind often the cause of indigestion—Its mode of operation explained—Also influences nutrition—Illustration from Shakspeare—Importance of attending to this condition of health enforced. 197-207 CHAPTER IV. THE DIFFERENT KINDS OF CONSTITUTION AND OF FOOD CONSIDERED WITH RELATION TO EACH OTHER. Man remarkable for the variety of his food; advantages of this — Man not guided by instinct to the choice of his food, but by ob- servation and experience ; his welfare thus intrusted to himself __Principle on which fitness of food ought to be determined; in- formation still much wanted—Nature of constitution to be con- sidered—Varieties of constitution or temperament; the lymphatic, nervous, sanguine, bilious, and mixed temperaments—Diet ought to be modified according to temperament; illustrations—Different kinds of food ; their classification and division into animal and vegetable—Londe's propositions regarding their relative digesti- bility—Animal food and its varieties ; its chemical composition no XU CONTENTS. test oi Its dietetic qualities—Division into fibrinous, gelatinous, and urouminous meats—Adaptation of each of these to different temperaments, ages, and states of health—Vegetable aliments and their properties ; principal divisions of them, and general remarks on their use and adaptation. 21W-231 CHAPTER V. ADAPTATION OF DIET TO CONSTITUTION, AGE, SEASON, AND MODE OF LIFE. Food to be adapted to constitution and circumstances—Diet must vary with time of life—Diet in infancy—The mother's milk the best; substitutes for it—Over-feeding a prevalent error—Diet after weaning—Too early use of animal food hurtful—Diet of children in the higher classes too exciting ; and produces scro- fula—Mild food best for children—Incessant eating very inju- rious—Proper diet from childhood to puberty—It ought to be full and nourishing, but not stimulating; often insufficient in board- ing-schools—Diet best adapted for mature age—Regimen powerful in modifying the constitution, mental as well as physical—Far- ther investigation required. 231-249 CHAPTER VI. ON DRINKS. Thirst the best guide in taking simple drinks—Thirst increased by diminution of the circulating fluids—The desire for liquids gene- rally an indication of their propriety—Much fluid hurtful at meals—Most useful three or four hours later—The temperature of drinks is of consequence—Curious fall of temperature in the stomach from cold water—Ices hurtful after dinner—Useful in warm weather, when digestion is completed and caution used— Cold water more dangerous than ice when the body is overheat- ed—Tepid drinks safest and most refreshing after perspiration- Kinds of drink—Water safe for every constitution—Wine, spirits, and other fermented liquors too stimulating for general use, but ( beneficial in certain circumstances—Test of their utility. 250-263 CHAPTER VII. ON THE PROPER REGULATION OF THE BOWELS. Functions of the intestines—The action of the bowels bears a na- tural relation to the kind of diet—Illustrations—And also to the other excretions—Practical conclusions from this—Different causes of inactivity of bowels—Natural aids to intestinal action —General neglect of them—Great importance of regularity of bowels—Bad health from their neglect—Especially at the age of puberty—Natural means preferable to purgatives—Concluding remarks. 264-276 Ikdex. 277-237 WOODCUTS. Under-jaw, 52.—Thoracic and Abdominal Viscera, 68.—Human Stomach, 69.—Stomach of a ruminating animal, 71.__Villous Coat of the Stomach, 75.—Opening into the Stomach of Alexis St. Mar- tin, 85.—Abdominal Viscera, 132.—Transverse section of the Abdo- men, 133.—Lacteals and Thoracic Duct, 138.—Thoracic Duct, 139. —Contents of the Abdomen after removal of the Intestines 143,—! Mucous Coat oi the Duodenum, 145. PART I. PHYSIOLOGY OF DIGESTION. CHAPTER I. GENERAL VIEW OF THE OBJECTS AND LAWS OF NUTRITION. Waste or loss of substance always attendant on action—In the ve- getable and animal kingdoms waste is greater than in the phy- sical—Living bodies are distinguished by possessing the power of repairing waste—Vegetables, being rooted in one place, are always in connexion with their food—Animals, being obliged to wander, receive their food at intervals into a stomach—Nutrition most active when growth and waste are greatest—In vegetables the same causes which increase these processes also stimulate nutrition—But animals require a monitor to warn them when food is needed—The sense of Appetite answers this purpose— The possession of a stomach implies a sense of Appetite to regu- late the supplies of food. Throughout every department of Nature waste is the invariable result of action. Even the minutest change in the relative position of inanimate objects cannot be effected without some loss of substance. So well is this under- stood, that it is an important aim in mechanics to discover the best means of reducing to the lowest possible degree the waste consequent upon motion. Entirely to prevent it is admitted to be beyond the power of man ; for however nicely parts may be adjusted to each other, however hard and durable their materials, and however smoothly motion may go on, still in the course of time loss of substance becomes evident, and repair and renewal become indis- pensable to the continuance of the action. It is thus a recognised fact, or general law of nature, that nothing can act or move without undergoing some change, however trifling in amount. Not even a breath of wind can pass along the surface of the earth without altering in some degree the proportions of the bodies with which it comes into contact ; and not a drop of rain can fall upon a stone without carrying away some portion of its substance. The smoothest and most accurately formed wheel, running along the most level and polished railroad, parts with some portion of its substance at every revolution, and in process of time is worn out and requires to be replaced. The same effect is forcibly, though rather ludicrously, exemplified in the great toe of the bronze statue of St. Peter at Rome, which in the course of centuries has been worn down to less than half its original size by the successive kisses of the faithful; and I venture to mention it, because it affords one of the best specimens of the operation of a principle, 26 WASTE ALWAYS ATTENDANT ON ACTION. the existence of which, from the imperceptibly small effect of any single act, might otherwise be plausibly denied. As regards dead or inanimate matter, the destructive influence of action is constantly forced upon our attention by everything passing around us; and so much human ingenuity is exercised to counteract its effects, that no re- flecting person will dispute the universality of its operation. But when we observe shrubs and trees waving in the wind, ami animals undergoing violent exertion, for year after year, and yet both continuing to increase in size, we may be inclined, on a superficial view, to regard living bodies as constituting exceptions to the rule. On more careful ex- amination, however, it will appear that waste goes on in living bodies not only without any intermission, but with a rapidity immeasurably beyond that which occurs in inani- mate objects. In the vegetable world, for instance, every leaf of a tree is incessantly pouring out some portion of its fluids, and every flower forming its own fruit and seed, speedily to be separated from, and lost to, its parent stem ; thus causing in a few months an extent of waste many hundred times greater than what occurs in the same lapse of time after the tree is cut down, and all its living opera- tions are at a close. The same thing holds true in the animal kingdom. So long as life continues, a copious ex- halation from the skin, the lungs, the bowels, and the kid- neys goes on without a moment's intermission ; and not a movement can be performed which does not at least partially increase the velocity of the circulatijn, and add something to the general waste. In this way, during violent exertion several ounces of the fluids of the body are sometimes thrown out by perspiration in a very few minutes ; where- as, after life is extinguished, all the excretions cease, and waste is limited to that which results from ordinary chemical decomposition. So far, then, the law that waste is attendant on action, applies to both dead and living bodies ; but beyond this point a remarkable difference between them presents itself. In the physical or inanimate world, what is once lost or worn away is lost for ever. There is no power inherent in the piston of the steam-engine by which it can repair its own loss of particles ; and consequently in the course of time it must either be laid aside as useless, or be remo- delled by the hand of the workman. But living bo;!j<\s whether vegetable or animal, possess the distinguishing LIVING BODIES CAN REPAIR THEIR WASTE. 27 characteristic of being able to repair their own waste and add to their own substance. The possession of such a power is, in fact, essential to their very existence. If the sunflower, which in fine weather exhales thirty ounces of fluid between sunrise and sunset, contained no provision within its own structure for replacing this enormous waste, it would necessarily shrivel and die within a few hours, as it actually does when plucked up by the roots ; and, in like manner, if man, whose system throws out every day five or six pounds of substance by the ordinary channels of excre- tion, possessed no means of repairing the loss, his organi- zation would speedily decay and perish. This very result is frequently witnessed in cases of shipwreck and other disasters, where, owing to the impossibility of obtaining food, death ensues from the body wasting away till it be- comes incapable of carrying on the operations of life. In some instances this waste has even proceeded so far that three-fourths of the whole weight of the body have been lost before life became extinct. It is impossible to reflect on these facts, and others of a similar kind, without having the conviction forced upon our minds, that in every department of nature expenditure of material is inseparable from action, and that in living bodies waste goes on so rapidly, and by so many different channels, that life could not be maintained for any length of time without an express provision being made for com- pensating its occurrence. In surveying the respective modes of existence of vege- tables and of animals, with the view of ascertaining by what means this compensation is effected, the first striking dif- ference between them which we perceive, is the fixfty of position of the one, and the free locomotive power of the other. The vegetable grows, flourishes, and dies, fixed to the same spot of earth from which it sprang ; and, however much external circumstances may change around it, it must remain and submit to their influence. If it be deprived of moisture and solar heat and light, it cannot go in search of them, but must remain to droop and to perish. If the earth to which its roots are attached be removed, and a richer soil be substituted than that which its nature requires, it still has no option.: it must grow up in.rank and unhealthy luxuriance, in obedience to an impulse which it cannot re- sist. At all hours and at all seasons it is at homo, and in direct communication with the soil from which its nourish- 28 ANIMALS RECEIVE FOOD AT INTERVALS. ment is extracted. And being thus without ceasing m contact with its food, it requires no store-house in which to lay up provision, but receives immediately from the earth, and at every moment, all that is necessary for its sustenance. But it is otherwise with animals. These not only enjoy the privilege of locomotion, but are compelled to use it, and often to go to a distance, in search of food and shelter. Consequently, if their vessels of nutrition were, like those of vegetables, in direct communication with external sub- stances, they would be torn asunder at every movement, and the animals themselves exposed either to die from star- vation, or to forego the exercise of the higher functions for which their nature is adapted. But the necessity for a constant change of place being imposed on them, a diffe- rent arrangement became indispensable for their nutrition : and the method by which the Creator hasremedied the incon- venience is not less admirable than simple. To enable the animal to move about, and at the same time to maintain a con- nexion with its food, He has provided it with a receptacle or stomach, where it is able to store up a supply of mate- rials from which sustenance may be gradually elaborated during a period of time proportioned to its necessities and mode of life. It thus carries along with it nourishment adequate to its wants ; and the small nutritive vessels im- bibe their food^rom the internal surface of the stomach and bowels, where the nutriment is stored up, just as the roots or nutritive vessels of vegetables do from the soil in which they grow. The possession of a stomach or receptacle for food is accordingly a characteristic of the animal system as contrasted with that of vegetables ; it is found even in the lowest orders of zoophytes, which in other respects are so nearly allied to plants. The sole objects of nutrition being to repair waste and to admit of growth, Nature has so arranged that within certain limits it is always most vigorous when growth or waste proceeds with the greatest rapidity. Even in vege- tables this relation is distinctly observable. In spring and summer, when vegetative life is most active, and when leaves, flowers, and fruit are to be formed and growth car- ried on, nourishment is largely drawn from the soil, and the elaboration and circulation of the sap are proportionally vigorous ; whereas in winter, when the leaves and flowers have passed away, and vegetable life is in repose, little nourishment is needed, and the circulation "of the sap is RELATION BETWEEN WASTE AND NUTRITION. 29 proportionally slow. In accordance with these facts, every one will recollect how freely a shrub or a tree bleeds, as it is called, when its bark is cut early in the season, and how dry it becomes on the approach of winter. It is the activity of the circulation in summer which renders its temporary suspension by transplanting so generally fatal at that season ; whereas, owing to the comparative sluggishness with which it is carried on in winter, its partial interruption is then at- tended with much less risk. In vegetables the quantity of nourishment taken in en- tirely depends on, and is regulated by, the circumstances in which they are placed. When they are exposed, as in spring and summer, to the stimulus of heat and light, all their functions are excited, waste and growth are acce- lerated, and a more abundant supply of nourishment be- comes indispensable to their health and 'existence; and hence, in a dry soil incapable of affording a copious sup- ply of sap, they speedily wither and die. Exposed to cold, on the other hand, and shaded from the light, their vitality is impaired, and the demand for nourishment greatly di- minished. This is uniformly the case in winter ; and many circumstances show that the change is really owing to the causes mentioned above, and not to anything inherent in the constitution of the vegetable itself. In tropical climates, for example, where heat, light, and moisture abound, ve- getable life is ever active, and the foliage ever thick and abundant; and even in our own northern region we are able, by artificial heat, so far to anticipate the natural order of the seasons, as to obtain the ripened fruit of the vine in the very beginning of spring. The whole system of forcing vegetables and fruit, so generally resorted to for the early supply of our markets, is, in truth, founded on the princi- ple we are now discussing ; and, by the regulated applica- tion of heat, light, and moisture, we are able to hasten or to retard, to a very considerable extent, the ordinary stages of vegetable life. But to ensure success in our operations, we must be careful to proportion the supply of nourishment to the state of the plant at the time. If, by the application of heat, we have stimulated it to premature growth and foliage, we must at the same time provide for it an ade- quate supply of food, otherwise its activity will exhaust itself, and indue* permature decay. Hence the regular watering which green-house plants require. But if we have 3* SO ANALOGY OF VEGETABLES AND ANIMALS. retarded its progress and lowered its vitality by excluding heat and light, the same copious nourishment will not only be unnecessary, but will probably do harm by inducing re- pletion and disease. In vegetables the absorption of food is thus regulated chiefly by the circumstances of heat, moisture, and light under which the plant is placed, and by the consequent necessity which exists at the time for a larger or smaller supply of nourishment to carry on the various processes of vegetable life. According to. this arrangement, nutrition is always most active when the greatest expenditure of ma- terial is taking place. When growth is going on rapidly, and the leaves are unfolding themselves, sap is sucked up from the earth in immense quantity ; but when these pro- cesses are completed as summer 'advances, and almost no fresh materials are required, except for the consolidation of the new growth and the supply of the loss by exhalation, a much smaller amount of nourishment suffices, and the sap no longer circulates in the same profusion. In autumn, again—when the fruit arrives at maturity, the leaves begin to drop off, and the activity of vegetable life suffers abate- ment—nutrition is reduced to its lowest ebb ; and in this state it continues till the return of spring stimulates every organ to new action, and once more excites a demand for an increased supply. Nor is the same great principle, of supply requiring to be proportioned to demand, less strikingly apparent in animals. Wherever growth is proceeding rapidly, or the animal is undergoing much exertion and expenditure of material, an increased quantity of food is invariably required ; and, on the other hand, where no new substance is forming, and where, from bodily inactivity, little loss is sustained, a com- paratively small supply will suffice. But as animals are subjected to much more rapid and violent transitions from activity to inactivity than vegetables are—and thus require to pass more immediately from one kind and quantity of nourishment to another, in order to adapt their nutrition to the ever-varying demands made upon the system—they evidently stand in need of some provision to enforce atten- tion when nourishment is necessary, and to enable them always to proportion the supply to the real wants of the body. Not being, like vegetables, in constant connexion with their aliment, they might suffer from neglect if they did not possess some contrivance to warn them in tima THE APPETITES OF HUNGER AND THIRST. 31 when to seek and in what quantity to consume it. But in endowing animals with the sense of Appetite, or the sen- sations of Hunger and Thirst generally included under it, the Creator has guarded effectually against the inconve- nience, and given to them a guide in every way sufficienl for the purpose. The very possession of a stomach or receptacle, into which food sufficient for a shorter or longer period can bd introduced at one time, and which we have already remark ed as characterizing all animals from the lowest to the highest, almost necessarily implies the coexistence of some watchful monitor, such as appetite, to enforce attention to the wants of the system, with an earnestness which it shall not be easy to resist. If this were not the case in man, for example—if he had no motive more imperative than reason to oblige him to take food—he would be constantly liable, from indolence and thoughtlessness, or the pressure of other occupations, to incur the penalty of starvation, without being previously aware of his danger. But the Creator, with that beneficence which distinguishes all His works, has not only provided an effectual safeguard.in the sensations of hunger and thirst, but, moreover, attached to their regulated indulgence a degree of pleasure which never fails to insure attention to their demands, and which, in highly civilized communities, is apt to lead to excessive gratification. Such being the important charge committed to the appetites of hunger and thirst, it will be proper to submit to the reader, before entering upon the consideration of the more complicated process of digestion, a few remarks on their nature and uses. CHAPTER II. THE APPETITES OF HUNGER AND THIRST. Hunger and Thirst, what they are—Generally referred to the stomach and throat, but perceived by the brain—Proofs and illus- trations—Exciting causes of hunger—Common theories unsatis- factory—Hunger sympathetic of the state of the body as well as of the stomach—Uses of appetite—Relation between waste and appetite—Its practical importance—Consequences of overlooking it illustrated by analogy of the whole animal kingdom—Disease Irom acting in opposition to this relation—Effect of exercise on appetite explained—Diseased appetite—Thirst—Seat of Thirst- Circumstances in which it is most felt—Extraordinary effects of injection of water into the veins in cholera—Uses of thirst, and rules for gratifying it. In the preceding, chapter I endeavoured to show, fist, 32 SEAT OF THE SENSATION OF HUNGER. that nutrition is required only because waste and a deposi- tion of new particles are continually going on, so that the body would speedily become exhausted if its constituent materials were not renewed ; secondly, that the sense oi appetite is given to animals for the express purpose of warning them when a fresh supply of aliment is needed as, without some such monitor, they would be apt to neglect the demands of nature ; and thirdly, that vegetables have no corresponding sensation, simply because, from their being at all times in communication with the soil, their nutrition goes on continuously in proportion as it is neces- sary, and without requiring any prompter to put it in action at particular times. If these principles be correct, it follows that, in the healthy state, (and let the reader be once for all made aware that in the following pages the state of health is always inplied, except where it is^otherwise plainly expressed,) the dictates of appetite will not be every day the same, but will vary according to the mode of life and wants of the system, and, when fairly consulted, will be sufficient to direct us both at what time and in what quantity we ought to take in either solid or liquid sustenance. But to make this perfectly evident, a few general observations may be required. It is needless to waste words in attempting to describe what hunger and thirst are : every one has felt them, and no one could understand them without such experience, any more than sweetness or sourness could be understood without tasting sweet or sour objects. Their end is mani- festly to proclaim that farther nourishment is required for the support of the system ; and our first business is, there- fore, to explain their nature and seat, in so far at least as a knowledge of these may4be conducive to our welfare. The sensation of hunger is commonly referred to the stomach, and that of thirst to the upper part of the throat and back of the mouth ; and correctly enough to this extent, that a certain condition of the stomach and throat tends to produce them. But, in reality, the sensations themselves, like all other mental affections and emotions, have their seat in the brain, to which a sense of the condition of the stomach is conveyed through the medium of the nerves. In this respect Appetite resembles the senses of Seeing, Hearing, and Feeling ; and no greater difficulty attends the explanation of the one than of the others. Thus, the cause which excites the sensation of colour is certain rays of light HUNGER A MENTAL SENSATION. 33 striking upon the nerve of the eye ; and the cause which excites the perception of sound is the atmospherical vibra- tions striking upon the nerve of the ear ; but the sensations themselves take place in the brain, to which, as the organ of the mind, the respective impressions are conveyed. In like manner, the cause which excites appetite is an impres- sion made on the nerves of the stomach ; but the feeling itself is experienced in the brain, to which that impression is conveyed. Accordingly, just as in health no sound is ever heard except when the external vibrating atmosphere has actually impressed the ear, and no colour is perceived unless an object be presented to the eye—so is appetite never felt, except where, from want of food, the stomach is in that state which forms the proper stimulus to its nerves, and where the communication between it and the brain is left free and unobstructed. But as, in certain morbid states of the brain and nerves- voices and sounds are heard, or colours and objects are seen, when no external cause is present to act upon the ear or the eye—so, in disease, a craving is often felt when no real want of food exists, and where, consequently, indul- gence in eating can be productive of nothing but mischief. Such an aberration is common in nervous and mental dis- eases, and not unfrequently adds greatly to their severity and obstinacy. In indolent unemployed persons, who spend their days in meditating on their own feelings, thi3 craving is very common, and, from being regarded and indulged as if it were healthy appetite, is productive of many dys- peptic affections.* If the correctness of the preceding explanation of the sensation of hunger be thought to stand in need of confir- mation, I would refer to the very conclusive experiments by Brrchet, of Lyons, as setting the question entirely at rest. Brachet starved a dog for twenty-four hours, till it became ravenously hungry, after which he divided the nerves which convey to the brain a sense of the condition of the stomach. He then placed food within its reach, but the animal, which a moment before was impatient to be fed, went and lay quietly down, as if hunger had never been experienced. When meat was brought close to it, it began to eat; and, apparently from having no longer any con- * Dyspepsia (from the Greek words 6vg, dus, bad, and Tzeirru, pepto, I concoct) is synonymous with indigestion. 34 NERVOUS COMMUNICATION BETWEEN THE sciousness of the state of its stomach--whether it was full or empty—it continued to eat till both it and the gullet were inordinately distended. In this, however, the dog was evidently impelled solely by the gratification of the sense of taste ; for, on removing the food at the beginning of the experiment to the distance of even a few inches, it looked on with indifference, and made no attempt either to follow the dish or to prevent its removal.* Precisely similar results ensued when the nervous sym- pathy between the stomach and brain was arrested by the administration of narcotics. A dog suffering from hunger turned listlessly from its food when a few grains of opium were introduced into its stomach. It may be said that 3uch a result is owing to the drug being absorbed and carried to the brain through the ordinary medium of the circulation; but Brachet has proved that this is not the case, and that the influence is primarily exerted upon the nerves. To establish this point, two dogs of the same size were selected. In one the nerves of communication were left untouched, and in the other they were divided. Six grains of opium were then given to each at the same mo- ment. The sound dog began immediately to feel the effects of the opium and became stupid, while the other continued lying at^the fire-side for a long time, without any unusual appearance, except a little difficulty of breathing. In like manner, when the experiment was repeated with that powerful poison nux vomica, upon two dogs similarly circumstanced, the sound one fell instantly into convul- sions, while the other continued for a long time as if no- thing had happened. These results demonstrate, beyond the possibility of doubt, the necessity of a free nervous communication be- tween the stomach and brain, for enabling us to experience the sensation of hunger. The connexion between the two organs is, indeed, more widely recognised in practice than it is in theory; for it is a very common custom with the Turks to use opium for abating the pangs of hunger when food is not to be had, and sailors habitually use tobacco for the same purpose. Both substances act exclusively on the nervous system. The relation thus shown to subsist between the stomach * Brachet, Recherches Experimental sur les Fonctions du Systgme Nerveux Ganglionaire, chap. iii. Paris edition. STOMACH AND BRAIN NECESSARY FOR ITS PERCEPTION. 35 and the brain, enables us in some measure to understand the influence which strong mental emotions and earnest intellectual occupation exert over the appetite. A man in perfect health, sitting down to table with an excellent ap- petite, receives a letter announcing an unexpected calamity, and instantly turns away with loathing from the food which, a moment before, he was prepared to eat with relish; while another, who, under the fear of some misfortune, comes to table indifferent about food, will eat with great zest on his " mind being relieved," as the phrase goes, by the receipt of pleasing intelligence. Excessive and absorbing emotion, even of a joyful kind, has the same effect. Captain Back tells us, in the interesting narrative of his last journey, that when he first heard of Captain Ross's return, " the thought of so wonderful a preservation overpowered, for a time, the common occurrences of life. We had but just sat down to breakfast, but our appetite was gone, and the day passed in a feverish state of excitement." (P. 245 ) In such cases no one will imagine that the external cause destroys ap- petite otherwise than through the medium of the brain. Occasionally, indeed, the aversion to food amounts to a feeling of loathing and disgust, and even induces sickness and vomiting—a result which depends so entirely on the state of the brain, that it is often excited by mechanical injuries of that organ. The analogy between the external senses and the appe- tite is in various respects very close. If we are wrapped in study, or intent on any scheme, we become insensible to impressions made on the ear or eye. A clock may strike, or a person enter the room, without our being aware of either event. The same is the case with the desire for food. If the mind is deeply engaged, the wants of the system are unperceived and unattended to—as was well exemplified in the instance of Sir Isaac Newton, who, from seeing the bones of a chicken lying before him, fancied that he had already dined, whereas, in reality, he had eaten nothing for many hours. Herodotus ascribes so much effi- cacy to mental occupation in deadening the sense of hun- ger, that he speaks of the inhabitants of Lydia having successfully had recourse to gaming as a partial substitute for food, during a famine of many years continuance. In this account there is, of course, gross exaggeration ; but it illustrates sufficiently well the principle under discussion. 36 CAUSE OF THE SENSATION OF HUNGER. Many attempts have been made, but without much suc- cess, to determine what the peculiar condition of the stomach is which excites in the mind the sensation of hunger. For a long time it was imagined that the pre- sence of gastric or stomach juice, irritating the nerves of the mucous membrane, was the exciting cause ; but it was at last ascertained that, after the digestion of a meal is completed, and the chyme has passed into the intestine, the gastric juice ceases to be secreted till after a fresh supply of food has been taken in.* It was next supposed that the mere emptiness of the stomach was sufficient to excite hunger, and that the sensation arose partly from the opposite sides rubbing against each other. But this theory is equally untenable ; for the stomach generally contains a sufficient quantity of air to prevent the actual contact of its sides, and, moreover, it may be entirely void of food, and yet no appetite be felt. It may be laid down, indeed, as a ge- neral rule, that an interval of rest must follow the termina- tion of digestion before the stomach becomes fit to resume its functions, or appetite is experienced in any degree of intensity ; and the length of time required for this purpose varies very much, according to the mode of life and to the extent of waste going on in the system. In many diseases, too, the stomach remains empty for days in succession, without any corresponding excitation of hunger. Even in healthy sedentary people, whose expenditure of bodily sub- stance is small, real appetite is not felt till long after the • stomach is empty, and hence one of their most common complaints is the want of appetite. Dr. Beaumont suggests a distended state of the vessels which secrete the gastric juice as the exciting cause of hunger, and thinks that this view is strengthened by the rapidity with which the juice is poined out after a short fast—a rapidity, he says, which cannot be accounted for except by supposing the juice to have existed ready made in the vessels or follicles by which it is secreted. But this * It is difficult, as in the above sentence, to avoid occasionally using expressions and referring to processes which have not pre- viously been explained ; but it would only lead to confusion and unnecessary repetition to stop at every page and introduce explana- tions, which, after all, the reader would scarcely understand on ac- count of their brevity. In the present instance, therefore, where I allude to the process of digestion, it is better to refer the reader to the outline given at the beginning of Chanter IV., than to distract his attention by introducing it also here. SYMPATHY BETWEEN SYSTEM AND STOMACH. 37 theory is not more satisfactory than the rest, for in the sudden flow of saliva into the mouth of a hungry man on the unexpected appearance of savoury viands, we have an instance of equally rapid secretion where there was evi- dently no storing up beforehand. Besides, there is an obvious relation between appetite and the wants of the system, which is not always taken sufficiently into account, and which is, nevertheless, too important to be overlooked. If the body be very actively exercised, and a good deal of waste be effected by perspiration and exhalation from the lungs, the appetite becomes keener, and more urgent for immediate gratification; and if it is indulged, we eat with a relish unknown on other occasions, and afterward experience a sensation of bien-itre or internal comfort per- vading the frame, as if every individual part of the body were imbued with a feeling of contentment and satisfaction, the very opposite of the restless discomfort and depression which come upon us, and extend over the whole system, when appetite is disappointed. An amusing example of the principle here inculcated is to be found in the Corres- pondence Inedite de Madame du Deffand,* where she de- scribes her friend Madame de Pequigni as an insatiable, bustling little woman who consumes two hours every day in devouring her dinner, and "eats like a wolf." But, then, remarks Madame du Deffand, by way of explanation, " II est vrai qu'elle fait un exercice enrage." There is, in short, an obvious and active sympathy be- tween the condition and bearing of the stomach and those of every part of the animal frame—in virtue of which. hunger is felt very keenly when the general system stands in urgent need of repair, and very moderately when no waste has been suffered. This principle is strikingly illus- trated during recovery from a severe illness. " In conva- lescence from an acute disease," as is well remarked by Brachet, " the stomach digests vigorously, and yet the in- dividual is always hungry. This happens because all the wasted organs and tissues demand the means of repair, and demand them from the stomach, which has the charge of sending them ; and, therefore, they keep up in it the con- tinual sensation of want, which, however, is, in this case, only sympathetic of the state of the body."t In alluding * Vol. iii., p. 40. Paris, 1309. t Brachet, Recherches Experimentales sur les Fonctions du Syl tome Nerveux Ganglionaire, p. 181. 4 38 RELATION BETWEEN WASTE *ND APPETITE. to this subject, Blaine observes, that " Hunger and thirst can only be satisfactorily explained by considering them as properties in the stomach by which it sympathizes with the wants of the constitution ; and hence it is that food taken in invigorates, even before it can be digested."* Hence also the prostration of strength that is felt when the stomach has been for some time empty. This sympathy is sometimes singularly manifest even in disease. In some cases of affection of the mesenteric glands, for example, where stomachic digestion remains for a time pretty healthy, and the general system suffers chiefly from the want of nourishment caused by the passage of the chyle into the blood being obstructed, the appetite continues as keen and often keener than before ; because the system, being in want of nourishment, and the stomach healthy, all its natural causes continue to act as before ; and accord- ingly, when food is taken, it is digested there as usual, but the chyle which is formed from it in the intestine can no longer be transmitted through the swollen glands in its usual healthy manner, to be converted into nutritive blood in the lungsr, and the system thus failing to receive the required supply, recommences its cravings almost as soon as if no food had been obtained. When the disease has advanced a certain length, however, fever springs up, and destroys both appetite and digestion. The effects of exercise also show very clearly the con- nexion between appetite and the state of the system. If we merely saunter out for a given time everyday, without being actively enough engaged to quicken the circulation and induce increased exhalation from the skin and lungs, we come in with scarcely any change of feeling or condi- tion ; whereas, if we exert ourselves sufficiently to give a general impetus to the circulation, and bring out moderate perspiration, but without inducing fatigue, we feel a light- ness and energy of a very pleasurable description, and ge- nerally accompanied by a strong desire for food. Hence the keen relish with which the fox-hunter sits down to table after a successful chase. This intimate communion between the state of the sys- tem and that of the stomach is a beautiful provision of Nature, and is one of the causes of the ready sympathy which has often been remarked as existing between the • Blaine's Outlines of the Veterinary Art, third edition, p. 273 RELATION BETWEEN WASTE AND APPETITE. 39 stomach and all the other organs—in other words, of the readiness with which they accompany it in its departure from health, and the corresponding aptitude of their disor- ders to produce derangement of the digestive function. Ap- parently for the purpose, among others, of thus intimately connecting the stomach with the rest of the system, it is supplied with a profusion of nervous filaments of every kind, which form a closely-interwoven nervous network in its immediate neighbourhood, and the abundance of which accounts for the severe and often suddenly fatal result of a heavy blow on the pit of the stomach. Without pretending to determine what the precise con- dition of the nerves of the stomach is, which, when con- veyed to the brain, excites the sensation of appetite, I think it sufficient for every practical purpose if we keep in mind, that the co-operation of the nervous system is ne- cessary for the production of appetite, and that there is a direct sympathy between the stomach and the rest of the body, by means of which the stimulus of hunger becomes unusually urgent where the bodily waste has been great, although a comparatively short time has elapsed since the preceding meal. Appetite, then, being given for the express purpose of warning us when a supply of food is necessary, it follows that its call will be experienced in the highest intensity when waste and growth—or, in other words, the operations which demand supplies of fresh materials—are most ac- tive ; and in the lowest intensity when, from indolence ant» the cessation of growth, the demand is least. In youth, accordingly, when bodily activity is very great, and a libe- ral supply of nourishment is required both to repair waste and to carry on growth, the appetite is keener and less discriminating than at any other period of life, and, what is worthy of remark, as another admirable instance of adap- tation, digestion is proportionally vigorous and rapid, and abstinence is borne with great difficulty ; whereas, in ma- ture age, when growth is finished and the mode of life more sedentary, the same abundance of aliment is no longer needed, the appetite becomes less keen and more select in its choice, and digestion loses something of the resistless power which generally distinguishes it in early youth. Articles of food which were once digested with ease, are now burdensome to the stomach, and, if not altogether re- 40 EVILS FROM NEGLECTING THE RELATION jected, are disposed of with a degree of labour and diffi- culty that was formerly unknown. Abstinence also is now more easily supported. When, however, the mode of life in mature age is ac- tive and laborious, and the waste matter thrown out of the system is consequently considerable, the appetite for food and the power of digesting it are correspondingly strong ; for in general it is onlv when the mode of life is indolent and inactive, and the waste consequently small, that the appetite and digestion are weak. So natural, indeed, is the connexion between the two conditions, that exercise is proverbially the first thing we think of recommending to improve the appetite and the tone of the digestive organs, when these are observed to be impaired ; and where po- sitive disease does not exist, no other remedy is half so effectual. But, as already noticed, exercise to be benefi- cial must be of a description calculated to increase the activity of the secretions and excretions; otherwise it cannot place the system in a condition to require an abun- dant supply or excite vigorous digestion. It is' highly important, to notice this natural relation between waste and appetite, and between appetite and di- gestion ; because, if it be real, appetite must b'e the safest guide we can follow in determining when and how much we ought to eat. It is true that in disease, and amid the factitious calls and wants of civilized life, its suggestions are often perverted, and that hence we may err in blindly following everything which assumes its semblance. The conclusion to be drawn from this, however, is, not that the sense of hunger will, if trusted to, generally mislead us, but only that we must learn to distinguish its true dic- tates before we can implicitly rely on its guidance. If, when fairly consulted, its dictates are found to be erro- neous, it will constitute the only known instance where the Creator has failed in the attempt to fulfil his own de- sign—an assumption not only repugnant alike to feeling and to reason, but, in fact, altogether gratuitous. For the apparent discrepancies which occasionally present them- selves between the wants of the system and the dictates of appetite, are easily explicable on the more solid ground of our own ignorance and inattention. Many practical errors arise from overlooking the rela- tion which nutrition ought to bear to waste and growth. BETWEEN WASTE AND APPETITE. 41 Thus, it is no uncommon thing for young men who have experienced all the pleasures of a keen appetite and easy digestion when growing rapidly or leading an active life, to induce severe and protracted indigestion, by continuing, from mere habit, to eat an equal quantity of food either when growth is finished and the system no longer requires the same extensive supply, or after a complete change from active to sedentary habits has greatly diminished that waste which alone renders food necessary. This is, in fact, one of the chief sources of the troublesome dvspeptic complaints often met with among the youthful inhabitants of our larger cities and colleges, and ought not to be lost sight of in the physical education of the young. The error, however, is unhappily not confined to the young, but extends generally to all whose pursuits are of a sedentary nature. There are numerous persons, especially in towns and among females, who, having their time and employments entirely at their own disposal, carefully avoid everything which requires an effort of mind or body, and pass their lives in a state of inaction entirely incompatible with the healthy performance of the various animal func- tions. Having no bodily exertion to excite waste, promote circulation, or stimulate nutrition, they experience little keenness of appetite, have weak powers of digestion, and require but a limited supply of food. If, while inactive and expending little, such persons could be contented to-follow nature so far as not to provoke appetite by stimulants and cookery, and to eat and drink only in proportion to the wants of the system, fliey would fare comparatively well. But having no imperative occupation and no enjoyment from active and useful exertion, their time hangs heavily on their hands, and they are apt to have recourse to eating as the only avenue to pleasure still open to them ; and, forgetful or ignorant of the relation subsisting between waste and nutrition, they endeavour to renew, in the present indul- gence of appetite, the real enjoyment which its legitimate gratification afforded under different circumstances. Pur- suing the pleasures of the table with the same ardour as before, they eat and drink freely and abundantly, and, instead of trying to acquire a healthy desire for food and increased powers of digestion by exercise, they resort to tonics, spices, wine, and other stimuli, which certainly excite for the moment, but eventually aggravate the mischief by 4* 42 EVILS FROM NEGLECTING THE RELATION, ETC. obscuring its progress and extent. The natural result of this mode of proceeding is, that the stomach becomes op- pressed by excess of exertion—healthy appetite gives way, and morbid craving takes its place—sickness, headache, and bilious attacks become frequent—the bowels are habitually disordered, the feet cold, and the circulation irregular—and a state of bodily weakness and mental irritability is induced, which constitutes a heavy penalty for the previous indul- gence. So far, however, is the true cause of all these phenomena from being perceived even then, that a cure is sought, not in abetter regulated diet and regimen, but from bitters to strengthen the stomach, laxatives to carry off the redundant materials from the system, wine to overcome the sense of sinking, and heavy lunches to satisfy the mor- bid craving which they only silence for a little. Some, of course, suffer in a greater and others in a less degree, ac- cording to peculiarities of constitution, mode of life, and extent of indulgence ; but daily experience will testify that, in its main features, the foregoing description is not over- charged, and that victims to such dietetic errors are to be met with in every class of society. The fact of Nature having meant the inactive and indo- lent to eat and drink less than the busy and laborious, is established not only by the diminished appetite and impair- ed digestion of human beings who lead a sedentary life, as contrasted with the keen relish and rapid digestion usually attendant on active exertion in the open air, but on a yet broader scale by the analogy of all other animals. In no- ticing this relation, Dr. Roget remarks, that " the greater the energy with which the more peculiarly animal functions of sensation and muscular action are exercised, the greater must be the demand for nourishment, in order to supply the expenditure of vital force created by these exertions. Com- pared with the torpid and sluggish reptile, the active and vivacious bird or quadruped requires and consumes a much larger quantity of nutriment. The tortoise, the turtle, the toad, the frog, and the chameleon will, indeed, live for months without taking any food." " The rapidity of de- velopement," he continues, " has also great influence on the quantity of food which an animal requires. Thus the caterpillar, which grows very quickly, and must repeatedly throw off its integuments, during its continuance in the larva state, consumes a vast quantity of food compared with FULL DIET INCOMPATIBLE WITH INACTION. 43 the size of its body ; and hence we find it provided with a digestive apparatus of considerable size."* Hence, too, the greater demand for food in infancy and youth when growth and activity are both at their height. In thus insisting on regular bodily and mental activity as indispensable to the enjoyment of a good appetite and sound digestion, the attentive reader will not, I trust, be disposed to accuse me of inconsistency because, when treating of muscular exercise in the former volume,! I explained the bad effects, and inculcated the impropriety, of indulging in any considerable exertion immediately before or after a full meal. It is true, as there mentioned, that exercise, either in excess or at an improper time, impairs the tone of the stomach; but it is not on that account the less true that bodily exertion, when seasonably and properly practised, is the best promoter of appetite and digestion which we pos- sess ; and it is only under the latter conditions that I now speak of it as beneficial and even indispensable to health. In a work like the present, it is obviously impossible to fence round every general proposition with the numerous limitations which an unusual combination of circumstances, or a departure from the state of health, might demand. And, even if possible, it would not be necessary, as the laws of exercise have been so fully explained in the volume alluded to, that their rediscussion here would unavoidably involve much repetition from its pages. At the same time, some warning remark may be required to prevent any risk of misconception, as it might otherwise be plausibly argued, for example, that there can be no such relation as I have alleged between waste and appetite, because a European perspiring under a tropical sun incurs great waste, and yet loses both appetite and digestive power. To render this a valid exception, it must be shown that the European is in- tended by Nature to live in a tropical climate, and that the diet to which he accustoms himself is that sanctioned by experience as the best adapted for his constitution ; be- cause, if neither is the case, his condition under such influ- ences must necessarily be more or less closely allied to the state of disease, and therefore beyond the sphere to which alone my remarks are meant to apply. But even in that in- stance there is less contradiction than might be imagined, * Roget's Bridgewater Treatise on Animal and Vegetable Phy- siology, vol. ii., p. 112. t Principles of Physiology, &c., chapters IV. and V. 44 FULL DIET INCOMPATIBLE WITH INACTION. for the waste of the system, being chiefly fluid, excites— not appetite, but its kindred sensation—thirst, to repair the loss by an unusual demand for refreshing liquids. So true is it that the Creator has established a relation between action and nutrition, that when we attempt for any length of time to combine a full and nutritious diet with systematic inactivity, the derangement of health which generally ensues gives ample proof of the futility of strug- gling' against His laws. Individuals, indeed, may be met with, who, from some peculiarity of constitution, suffer less than the generality of mankind from making the ex- periment ; but even those among them who escape best, generally owe their safety to the constant use of medicine, or to a natural excess in some of the excretory functions, such as perspiration or the urinary or alvine discharges, by means of which the system is relieved much in the same way as by active exercise ; and hence the remark made by Hippocrates, that severe perspirations arising during sleep without any other apparent cause, are a sure sign that too much nourishment is made use of. In others, again, the day of reckoning is merely delayed, and there is habitually present a state of repletion, which clogs the bodily func- tions, and may lead to sudden death by some acute disease wher the individual is apparently in the highest health. I am acquainted with several individuals of this description, who, in the absence of all bodily exercise, are accustomed to live very fully—to eat in the morning a hearty breakfast, with eggs, fish, or flesh—a good solid luncheon, with wine or malt liquor, in the forenoon—a most substantial dinner, with dessert and several glasses of wine, and afterward tea and wine and water, in the evening—and who, nevertheless, enjoy tolerably good digestion. But this advantage is gene- rally only temporary, and even when permanent can scarcely be considered as a boon ; because it is gained at the direct expense either of a very full habit of body and an unusual liability to abdominal congestion and all its attendant evils, or of frequent and profuse perspirations, and severe attacks of bowel complaint, endangering life ; so that, strictly con- sidered, such cases are no exceptions to the general rule. It is, then, no idle whim of the physician to insist on active exercise as the best promoter of appetite and di- gestion. Exercise is, in fact, the condition"without which exhalation and excretion cannot go on sufficiently fast to DEFICIENT DIET AND EXCESS OF LABOUR. 45 clear the system of materials previously taken in; and where no waste is incurred, no need of a fresh supply, and, conse- , quently, in a healthy state of the system, no natural appetite, can exist. It is, therefore, not less unreasonable than vain for any one to insist on possessing, at the same time, the incompatible enjoyments of luxurious indolence and a vigo- rous appetite—sound digestionof a hearty meal, and general health of body ; and no one who is aware of the relation subsisting between waste and appetite, can fail to perceive the fact, and to wonder at the contrary notion having ever been entertained. Among the operative part of the community we meet with innumerable examples of an opposite condition of the system, where, from excess of labour, a greater expenditure of energy and substance takes place than what their defi- cient diet is able to repair. It is true that the disproportion is generally not sufficient to cause that immediate wasting which accompanies actual starvation, but its effects are, nevertheless, very palpably manifest in the depressed buoy- ancy, early old age, and shorter lives of the labouring classes. Few, indeed, of those who are habitually sub- jected to considerable and continued exertion survive their forty-fifth or fiftieth year. Exhausted at length by the constant recurrence of their daily task and imperfect nour- ishment, they die of premature decay long before attaining the natural limit of human existence. In those states of the system, again, such as fever, during the continuance of which most of the secretions are vitiated, and that of the gastric juice often entirely suppressed, and where food would consequently be hurtful rather than advantageous, appetite is scarcely felt, and loathing often occupies its place. But the moment that, by the diminu- tion of the disease, the secretions and exhalations begin to return to their healthy state, and nutrition is resumed, appetite begins to be again felt, and by and by becomes abundantly vigorous, in order to restore the system to its former state. The utmost caution, however, is still required in its gratification, as a premature indulgence is almost certain again to stop the secretions and to produce a relapse. Ignorance of this principle among the community at large, and the consequent error of giving food when there is no demand for it, and no gastric juice to digest it, often do more to defeat the best laid plan of cure than the severity 46 INFLUENCE OF DISEASE ON APPETITE. of the disease itself. The sick man's friends, in their anxiety to support his strength, too frequently turn a deaf ear to every caution which is suggested, arid stealthily administer sustenance when the system docs not require it, and when it serves only to aggravate the danger and increase the weakness of the patient. Since the first publi- cation of the preceding passage, I have seen a striking example of its truth. The patient was gradually recovering from inflammation of the chest, for the cure of which low diet was for a time indispensable. By way of supporting the diminished strength, the relations began to give, prema- turely and clandestinely, about double the quantity of food which was prescribed. For twenty-four hours an increase of strength was felt accordingly ; but very soon it passed into febrile excitement with a quick pulse and increased weakness. A dangerous relapse followed, and its cause was then found out. Abstinence was again enforced, and tartar emetic given to excite nausea. To the surprise of the very injudicious friends, the excitement began almost immediately to subside and the strength to improve where they had just seen it fast giving way under a full diet. Appetite, it ought to be observed, may, like other sensa- tions, be educated or trained to considerable deviations from the ordinary standard of quantity and quality—and this ob- viously for the purpose of enabling man to live in different climates and under different circumstances, and avoid being fixed down to one spot and to one occupation. In civilized life, however, we are accustomed to take undue advantage of this capability, by training the appetite to desire a greater quantity of food'than what the wants of the system require, and stimulating its cravings by a system of cookery little in harmony with the intentions of Nature. But this is evidently an abuse, and no argument whatever against the sufficiency of its natural indications to lead us right. But the most common source of the errors into which we are apt to fall in taking appetite as our only guide, is un- questionably the confounding of appetite with taste, and con- tinuing to eat for the gratification of the latter long after the former is satisfied ; just as the dog already mentioned ate till the oesophagus was distended, although it did not experience the slightest sensation of hunger.* In fact, the whole science of a skilful cook is expended in producing * See p. 34. APPETITE A FAIR INDICATION OF WANT. 47 this willing mistake on our part; and he is considered decidedly the best artiste whose dishes shall recomend them- selves most irresistibly to the callous palate of the gour- mand, and excite on it such a sensation as shall at least remind him of the enviable excellence of a natural appetite. If we were willing to limit the office of taste to its proper sphere and to cease eating when appetite expressed content, indigestion would be a much rarer occurrence in civilized communities than it is observed to be. Viewed, then, in its proper light, appetite is to tie regard- ed as kindly implanted in our nature for the express end of proportioning the supply of nourishment to the wants of the system ; and if ever it misleads us, the fault is not in its unfitness for its object, but in the artificial training which it receives at our own hands, and in our own habitual ne- glect of its dictates. When we attend to its real indica- tions, we eat moderately, and at such intervals of time as the previous exercise and other circumstances render neces- sary ; and in so doing we reap a reward in the daily enjoy- ment of the pleasure which attends the gratification of healthy appetite. But if we err, either by neglecting the timely warning which it gives, or by eating more than the system requires, mischief is sure to follow. In the former case waste continues to make progress till the body be- comes exhausted; and in almost exact proportion do the cravings of appetite become more and more intense, till they pass into those of uncontrollable hunger, which over- throws all obstacles, and seeks gratification at the risk of life itself. In the latter case indigestion, gloomy depres- sion, and repletion with its concomitant evils, make their appearance, and either imbitter or cut short existence. Mischief sometimes arises also from people not being sufficiently aware that, in common with other sensations, appetite may be so far deranged by disease as to give very incorrect and unnatural indications. It often happens, for example, that a patient shivers and complains of cold, when we know by the thermometer that the heat of the skin is really above instead of below the natural standard. In like manner, in some morbid states of the nervous system a craving is often felt which impels the patient to eat, but which is not true hunger ; and here food, if taken, is digest- ed with great difficulty. Occasionally, on the other hand, no desire for food is experienced when the system really 48 APPETITE DISORDERED BY DISEASE--THIRST--ITS SEAT. needs it, and when it would be digested with ease if intro- duced into the stomach. Esquirol alludes to cases of this description, and I have met with similar examples. Voison also mentions that, in the Hospital of Incurables, in Paris, there are some idiots so low in the scale of intel- ligence, as to make no attempt to take the food which is placed before them, although they eat and digest readily when fed by others. Sometimes, again, appetite is de- praved in quality, and the patient desiderates the most nause- ous and refiulsive kinds of food, such as earth, chalk, coals, or excrement. There are states, too, in which the appetite is prodigiously increased, and the patient consumes incre- dible quantities of food—which, however, are very imper- fectly digested. Charles Domery, for instance, when a French prisoner, at Liverpool, consumed, in one day, four pounds of cow's udder and ten pounds of raw beef, with two pounds of tallow candles and five bottles of porter; and, although allowed the daily rations of ten men, he was still not satisfied. Baron Percy speaks of another man, who ate twenty-four pounds of~beef in as many hours, and thought nothing of swallowing a dinner prepared for fifteen German boors. I once attended a patient who was afflict- ed with a similar inordinate craving, and whose only plea- sure was in eating. In such cases no restraint, except actual coercion, is sufficient to prevent indulgence ; but the craving itself is as much the product of disease as the shivering in the beginning of fever, and can no more be removed by reasoning than the sensation of cold can be re- moved by telling a patient that his skin is thermometrically warm. But these, being cases of disease, do not in any degree militate against the accuracy of the exposition above given of the healthy uses of appetite. The general considerations which I have just submitted to the reader on the subject of appetite for food, apply so closely to the sensation of Thirst, that to enter into any detail concerning the latter would be little else but to be guilty of repetition. I shall, therefore, limit myself to a very few remarks. Thirst is generally said to have its seat in the back of the mouth and throat; but the condition of these parts is mere- ly a local accompaniment of a want experienced by the whole frame, and perceived by the nervous system. Local applications, accordingly, go but a short way in giving re- THIRST VARIES ACCORDING TO FOOD. 49 lief, while the introduction of fluids by any other channel —by immersion in a bath, by injection into the veins, or through an external opening into the stomach—is sufficient to quench thirst without the liquid ever touching the throat. The affection of that part, therefore, is merely a result of the state of the system, and not itself the cause of thirst. Thirst, or a desire for liquids, is experienced in its great- est intensity when the secretion and exhalation of the ani- mal fluids is most active ; and it is consequently most urgent in summer, in warm climates, and in persons engaged in severe exertion, particularly if exposed at the same time to a heated atmosphere. Blacksmiths, glass-blowers, en- gineers, and others, whose employment exposes them to the heat of furnaces, and in whom perspiration is excessive, are accordingly almost constantly under the influence of thirst; whereas those who are employed in professions re- quiring only moderate exertion in a temperate atmosphere, and in whom the fluid secretions are very moderate, rarely experience the sensation in an urgent degree. For the same reason great loss of blood induces excessive and in- tolerable thirst; and hence, in the battle-field, the gene- rous self-denial of him who passed the cup to his wounded neighbour, without stopping even to moisten his own lips, cannot be too highly appreciated. Thirst varies in intensity also according to the nature of the food. If the diet be hot and stimulating, such as results from a free admixture of spices or salt, the desire for drink is greatly increased. The same thing happens if the food be of a dry and solid nature. The purpose of the increased thirst in the former circumstances is mani- festly to dilute and diminish the excess of stimulant, and thereby prevent the injury which it would otherwise in- flict. The same principle explains the thirst experienced by those who drink too much wine. In instances of thi3 kind I have heard great thirst in the evening and during the night complained of as habitual, without the person even suspecting that it was owing to the wine ; and yet, on ab- staining from the latter, the thirst very soon disappeared. Continued thirst, it is well known, is much more into- lerable than continued hunger. The mass of circulating fluid in the body is very great, and, as the various excre- tions consist chiefly of fluid matter, it necessarily happens that, when these have been eliminated for a considerable 5 50 THIRST MORE URGENT THAN HUNGER—ITS USES. time without any liquid being received into the system, the proportion of solid matter in the body becomes unduly large. The blood, consequently, becomes thicker and changed in quality, and much more irritating than it is in its natural state. The craving of thirst is thus generally ren- dered more urgent and overpowering than that of hunger. In Asiatic Cholera the watery portion of the blood, on which its fluidity depends, is drained off with frightful rapidity ; and the result is, in the first place, an almost complete stoppage of the circulation, and, in the second, a constant craving for drink to supply the place of the lost serum, which consists chiefly of water holding some of the alkaline salts in solution. This circumstance explains in some degree the extraordinary effects which have been produced, even in the worst stages of the disease when life seemed almost extinct, by injecting large quantities of saline solutions into the veins. Patients apparently on the verge of existence, cold, pulseless, and inanimate, have, in the course of a few minutes, been enabled by this means to sit up in bed, and to exhibit all the signs of restored strength and health. The effect, it is true, was rarely permanent, but for the time it was so wonderful as often to look like restoration from the dead.* Fluids taken into the stomach, it is proper to observe, are not subjected to the slow process of digestion, but are absorbed directly into the system ; so that, when we take a moderate draught, the whole of it is imbibed from the stomach in a very few minutes. Keeping in view this fact, and the above striking illustration of the influence of the condition of the blood upon the body at large, it be- comes easy to conceive why, in a state of exhaustion from abstinence, drink should be more speedily restorative and refreshing than food. Thirst, like appetite for food, is intended to direct us when and in what quantity we ought to drink ; and so long as we lead a life of ordinary health and activity, and con- fine ourselves to the fluids with which Nature provides us, there is little chance of our going far wrong by listening to its calls. But when we become indolent and dyspeptic, or resort to the use of fermented and stimulating liquors, which excite a thirst not recognised by Nature, the prin- » For some very curious details on this subject, the reader mav eoniult the last edition of Dr. Mackintosh's Practice of Physic. MASTICATION. 51 ciple ceases to apply. As present, however, my obser- vations refer entirely to such simple drinks as water, and to the state of health ; and I shall touch upon other liquids when treating of diet in a subsequent part of the volume. Many persons, without experiencing any real thirst, habitu- ally indulge in potations of water or beer at all hours of the day, and to an extraordinary extent, and feel unhappy when suddenly restricted in the indulgence. But this temporary discomfort ought not to be considered as indi- cating that these potations are really necessary, because the same result happens in the analogous instances of smok- ing or snuffing. All three are abuses and perversions of Nature; and the uneasiness attending the sudden cessation of the beer or water drinking is no more a proof of either fluid being required, than that consequent on giving up cigar smoking is an indication that Nature designed the lungs for the reception of the impure effluvia of the tobac- co leaf instead of the fresh breezes of heaven. CHAPTER III. MASTICATION, INSALIVATION, AND DEGLUTITION. Mastication—The teeth—Teeth, being adapted to the kind of food, vary at different ages and in different animals—Teeth classed and described—Vitality of teeth, and its advantages—Causes of disease in teeth—Means of protection—Insalivation, and its uses —Gratification of taste in mastication—Deglutition. Having seen that a regular supply of nourishment is carefully ensured by the constantly returning impulses of Appetite, we come next to examine the mode in which the food is prepared for becoming a constituent part of the animal machine, and endowed with the properties of life. The first important step in the complicated process of digestion, is that by which the food, after being received into the mouth, is mixed with the saliva and broken down till it becomes of a uniform pulpy consistence, fit for being easily swallowed and acted upon by the gastric juice on it sarrival in the stomach. The term mastication, or chew- ing, is used to denote this operation ; and the chief instru- ments by which it is performed are the teeth, the jaws, the muscles which move the jaws, the tongue, and the Balivary glands. On each of these we shal offer a few observations. The teeth vary a good deal according to the kind of food on which the animal is destined to live ; but in man 62 DIFFERENT KINDS OF TEETH. and the higher orders of animals they may be divided into three distinct groups : 1st, The incisor or cutting teeth, being the eight broad and flat teeth with a sharp cutting edge seen in front of the upper and lower jaws, and marked I in the'subjoined wood-cut, which represents one-half of the lower jaw, and consequently only one-fourth of the whole number of teeth. Thus we find only two incisors marked .in the wood-cut, although there are eight of them in all, viz., two more are on the other side of the lower jaw, and four corresponding ones in the upper. 2rf, The cuspidati, canine, or dog teeth, being the sharp-pointed, roundish- bodied teeth, four in number, one, C, in contact with each of the outer incisor teeth, and called canine from being large in the dog and carnivorous animals, and used by them for the purpose of seizing and tearing their food; and, 3d, The molares or grinders, B G, twenty in number, situated at the back part of the jaw, and so called from their office being to grind or bruise the food subjected to their action.* The term grinders, however, is sometimes restricted to the three back teeth on each side, marked G, and seen to have double roots and a broad grinding surface ; and the two, B, inter- vening between them and the cuspidati are styled bicus- pidati or double-speared, from bearing a greater resemblance to a double-headed canine tooth than to the other grinders. * In Latin cuspis signifies the point of a spear; canis, a dog • mola, a mill; incisor, anything which cuts. RELATION BETWEEN TEETH AND FOOD. 53 The teeth are modified in different animals to suit their habits of life. In herbivorous animals the canine teeth, for which they have no use, are comparatively undeveloped ; whereas in carnivorous animals, which tear their prey in pieces, the canine teeth are large, powerful, and pointed, and the incisors comparatively small. In these animals they constitute what are properly called the tusks, and in some species they are of a truly formidable character. The molar or grinding teeth differ in like manner, according to the nature of the food. In herbivorous and granivorous animals they are large and powerful, and to increase their efficiency the lower jaw admits of considerable lateral mo- tion in a horizontal direction ; whereas, in carnivorous ani- mals, it admits of motion only upward and downward, as in opening and shutting the mouth. The lateral grinding motion is very evident in ruminating animals, such as the cow, which, after having filled its stomach with provender, is generally seen to lie down and ruminate, or chew the cud as it is catted—the rumination consisting in bringing up small masses of herbage from the stomach, and submitting them to a thorough mastication or grinding between its molar teeth before being again swallowed and digested. From this relation between the food and the organs of mastication, naturalists can tell with certainty, by simply inspecting the teeth, on what kind of food the animal to which they belong is intended to live ; and as the teeth of man partake of the characters of those of both herbivorous and carnivorous animals, there cannot be a doubt that his diet was intended to be of a mixed kind, not confined ex- clusively to either the vegetable or thfi animal kingdom. Hard and resisting as the teeth appear, they must still be regarded as living structures. Anatomically speaking, each tooth is divided into three parts : the fang or root, implant- ed in the socket of the jaw-bone ; the neck, or portion en- circled by the gum ; and the white crown, appearing above the gum, and covered with enamel. The root of each tooth is perforated longitudinally by a small canal, through which the bloodvessels and nerve are admitted to its central parts. From these bloodvessels the tooth derives its nourishment when growing; but they after- ward almost entirely disappear. From the nerve it derives that sensibility which makes us instantly aware of the con- tact of bodies either too hot or too cold with the teeth; 5* 54 VITALITY OF THE TEETH. and which, when the nerve is diseased, gives rise to the racking pain of toothache. So effectually is life maintained in the teeth by this pro- vision of vessels and nerves, that a tooth newly extracted from the socket of a young animal, and implanted in the fleshy comb of a cock, has been found to adhere and retain its vitality; and, in like manner, if, in early life, a tooth extracted by accident be immediately replaced in its socket, it will generally adhere and live. The visible part or crown of the teeth is covered with a very hard white ivory-looking substance called enamel, which serves to prevent it from being worn down by friction, and into which neither bloodvessels nor nerves have been observed to penetrate. Owing to this structure, the tooth can be safely exposed without sustaining damage—a privi- lege on which most persons will be disposed to place a higher value after having experienced the pains consequent upon injury of the nerve from a portion of the enamel being broken off. An obvious advantage attending the vitality of the teeth is, that it enables them to accommodate themselves to the growth of the jaw and the rest of the system at the diffe- rent periods of life. In early infancy, when the human being is designed to live exclusively on his mother's milk, which of course requires no mastication, and, consequently, no teeth, the latter are still imperfectly formed and entirely hidden in the jaw : it is only at the end of some months that the front or cutting teeth begin to appear ; and the whole set of milk, deciduous, or falling-out teeth, twenty in number,' is not completed till about or after the third year. In the course of three or four years more, however, growth has advanced so far that the first set of teeth no longer fill the jaw ; and they soo'n begin to be displaced by the second or perma- nent set, the gradual developement of which commences at that period of life, and is not finished till the appearance of the last four grinders or wisdom-teeth, about the age of maturity. It is a curious fact, that the infant is born with the rudi- ments of both sets of teeth in the jaw at the same time although neither makes its appearance till long after birth. The permanent teeth lie in a line under the milk-teeth, and it is from their growth causing the gradual absorption of the roots of the first teeth that the latter no longer retain PRESERVATION OF THE TEETH. 55 their hold of the jaw, but drop out as soon as the others are ready to protrude. In the preceding wood-cut the situation of the permanent teeth before they emerge from the jaw is rudely represented at A, where the outer surface of the jaw- bone has been removed on purpose to show the appearance of the roots. But nothing of this kind is to be found in the adult jaw, the parts marked A being inserted in the plate merely to illustrate what was once the position which the permanent teeth occupied. The changes in the condition of the teeth, it may be remarked in passing, indicate clearly what species of food Nature has intended for us at different ages. In early in- fancy, when no teeth exist, the mother's milk is the only nutriment required ; and in proportion7as the teeth begin to appear, a small addition of soft farinaceous food prepared with milk may be made with propriety, and gradually in- creased. But it is impossible to look at the small jaw, moderate muscle, and imperfect teeth of early life, without perceiving that only the mildest kinds and forms of animal food are yet admissible, and that the diet ought to consist essentially of soft and unirritating materials. It is not till the permanent teeth have appeared, that a full proportion of the ordinary kinds of butcher-meat becomes either bene- ficial or safe. The teeth, being living parts, and at the same time en- dowed with a mechanical function, are liable to injury in both capacities. Being composed chiefly of earthy matter, such as phosphate and carbonate of lime, the contact of strong acids decomposes their substance, and leads to their rapid decay. Hence the whiteness produced by acid tooth- powders and washes is not less deceitful than ruinous in its consequences ; and hence also great caution is necessary in swallowing the acid drops frequently prescribed by the physician, which ought never to be allowed to come into contact with the teeth. The teeth being constantly moistened with saliva, have a tendency to become incrusted with the tartar or earthy matter which it contains in solution, and which is separated from it partly by the evaporation of the more fluid consti- tuents in breathing, and partly by chemical decomposition. As this incrustation not only destroys the beauty of the ieeth, but also promotes their decay, it becomes an object of care to remove it as soon as it is formed ; and the most 56 PRESERVATION OF THE TEETH. effectual mode of doing so is to brush the teeth regularly twice a day—especially in the morning, when the quantity is greatest—with a brush dipped in'soft water, till eve^Y particle is removed. - The addition of any soft impalpable powder will assist in the effect; but nothing capable of acting chemically on the teeth, or of injuring them by fric- tion, ought ever to be resorted to. Washing the mouth after every meal is also a good preservative.* When the teeth are not used for a time, and when di- gestion is impaired, the quantity of tartar which accumu- lates on them is very great. Hence they are always most incrusted in the morning, and in fevers and other affections where no food is taken, and the stomach is at the same time disordered. I have seen one instance in which a thick crust of tartar was removed by a dentist in the belief-of its being a diseased tooth—the 'tooth itself on which it was formed being left in the jaw perfectly sound. When the tartar is not duly removed, its presence injures the teeth, irritates the gums, and generally leads, sooner or later, to considerable suffering. The regular washing and brushing abovementioned ought, therefore, to be sedulously practised at every period of life, and taught as a duty to the- young. When digestion is very vigorous, the health good, and the diet plain and containing a full proportion of vegetable matter, the deposition of tartar seems to be di- minished, and the teeth to be naturally of a purer white. Many rustics and savages thus possess teeth which would be envied in a town. When digestion is impaired, and acidity prevails in the stomach, the mucous secretions in the mouth also become altered in character, and by their incessant contact injure and even destroy the teeth. From this cause we often see the teeth of young people in a state of complete decay. They are, in reality, the subjects of chemical decomposition, * M. Cadet de Qassicourt recommends thefollowing compound as a safe and excellent dentrifice, viz., of white sugar and powdered charcoal each one ounce, of Peruvian bark half an ounce, of cream of tartar one drachm and a half, and of canella twenty-four grams, well rubbed together into an impalpable powder. He describes it as strengthening to the gums and cleansing to the teeth, and as de- stroying the disagreeable odour in the breath which so often arises from decaying teeth ; and, as ^.preventive of toothache, I have heard washing the mouth and teeth twice'a day with salt and water strongly recommended by a gentleman who had both experienced and observed much benefit from it. SALIVA AND ITS USES. 57 smd eaten away by the morbid secretions of the mouth ■ and hence, in such cases, we generally find the individual complaining of heat and soreness of the tongue, gums, and mouth, and occasionally of the teeth being "set on edge.1' Considered as living parts, the teeth require some addi- tional care. In that capacity they are exceedingly apt to suffer from sudden changes of temperature. Being from their solidity rapid conductors of heat, their internaf nerv« speedily becomes affected by the alternations of tempera- ture to which they are daily exposed, both in taking food and in the change from a warm to a cold atmosphere. It is a not uncommon practice, for example, to take a glass of cold wine or water immediately after finishing a plateful of very hot soup ; and it is quite usual to take tea and coffee and every kind of meat as hot as they can possibly be swallowed—than which practices it would be difficult to imagine anything more hurtful to the teeth. For the same reason, in going out at night from a warm room to the cold air, it is desirable to protect the teeth from the influence of the sudden change, bv breathing through two or three folds of a silk handkerchief or through a woollen comforter. When the teeth and lower part of the face are left exposed in such circumstances, rheuma- tism and toothache not unfrequently ensue from the direct impression of the cold air upon parts rendered more sus- ceptible by the preceding heat. The great source of injury to the teeth, however, both in childhood and in mature age, is disordered digestion. If the health be good, and the stomach perform its functions with vigour, the teeth will resist much exposure without sustaining injury. But if these conditions fail, they will rarely continue long unscathed. It is almost always from the latter cause that, in infancy, teething so oftea gives rise to serious constitutional dis- order. Something more, however, than the mere action of the teeth and jaws is required to prepare the morsel for being swallowed. If we take a bit of dry biscuit or mealy potato into the mouth, and attempt td masticate it, we en- counter at first no small difficulty from the stiffness and resistance of the dry mass, and feel instinctively that it would be in vain to attempt to swallow it, until moistened either by continued mastication or by the admixture of fluid 58 mast'ication--RUMINATION. from without. In ordinary states of the system, accord- ingly, a fluid called saliva or spittle is copiously secreted and poured into the mouth for this very purpose ; and the process by which its due admixture with the contents of the mouth is accomplished is called the insalivation of the food. To provide this necessary fluid, and to connect its sup- ply directly with the process of mastication to which it is subservient, several glands for its secretion have been placed in the immediate neighbourhood of the mouth and jaws, in such a way that the latter cannot be opened and shut without affording them a stimulus, and still farther increasing the secretion which the presence of the morsel is itself sufficient to begin. From this arrangement it follows, that the more perfectly mastication is performed, the more thoroughly does the morsel become impregnated with the salivary fluid, and the better fitted is it rendered for subsequent deglutition and digestion. The apparatus of mastication varies according to the kind of food on which the animal is destined to live ; but in the higher orders of animals it consists essentially of the parts already mentioned. In some animals, however, which live on soft gelatinous food—as the whale—no teeth are to be found, because their peculiar power is not required. In others—as the granivorous or grain-eating birds—the grinding or triturating process is effected, not in the mouth, but in the gizzard, where the food (mixed with gravel, which the animal is instinctively impelled to swallow for the purpose) is effectually bruised and softened down by the strong muscles which constitute the greater part of its substance. In these instances the gravel is the grinding instrument, and without its presence digestion cannot be carried on any more than it could in man without the agency of teeth. 6 J The degree of mastication required varies also according to the mode of life of the animal, and the digestibility of its food. Animal food, for example, being easy of digestion, requires less mastication than vegetable food, which is more difficult. This is so much the case, that most ani- mals which live on fresh vegetable matter spend half their waking hours in ruminating or remasticating the food, which they have already cropped and stored up for the purpose in one of their four stomachs. To this necessary MASTICATION OF THE FOOD. 59 act in them, Providence seems to have attached a high de- gree of gratification, for the very purpose of ensuring its regular performance. Man, being naturally omnivorous, or adapted for the digestion of both animal and vegetable substances, holds, as it were, an intermediate place in regard to the rapidity of mastication. He is neither obliged to ruminate like the cow, nor can he beneficially bolt his food with the rapidity displayed by birds of prey. His object is merely to reduce the alimentary mass to a soft and pulpy consistence, and digestion is promoted or retarded in exact proportion as he approaches or falls short of this point. Hasty mastication is consequently injurious, because it prevents the food from being sufficiently broken down and impregnated with saliva; and the more uncommon error of protracted mastication is also injurious, owing to the undue dilution which the mass sustains from the overflow of the salivary secretion. Due mastication being thus essential to healthy diges- tion, the Creator, as if to ensure its being adequately per- formed, has kindly so arranged, that the very act of mas- tication should lead to the gratification of taste—the mouth being the seat of that sensation. That this gratification of taste was intended, becomes obvious when, we reflect that, even in eating, Nature makes it our interest to give atten- tion to the process in which we are for the time engaged. It is well known, for example, that, when food is presented to a hungry man, whose mind is concentrated on the in- dulgence of his appetite, the saliva begins to flow unbidden, and what he eats is consumed with a peculiar relish and is easily digested. Whereas, if food be presented to an individual who has fasted equally long, but whose soul is absorbed in some great undertaking or deep emotion, and who is consequently insensible to the gratification of taste, it will be swallowed almost without mastication, and with- out sufficient admixture with the saliva—now deficient in quantity—and, therefore, lie on the stomach for hours un- changed. In this point of view the peculiarly English custom of reading the newspapers or magazines during breakfast is more hurtful than one would suppose ; and many dyspeptics have been surprised at the benefit result- ing from its discontinuance. However, therefore, philoso- phy and morality condemn the undue cultivation of our bodily appetites, it cannot be denied that a certain degree 60 USES OF MASTICATION. of attention to taste, and to the pleasures of appetite, r* both reasonable and beneficial ; and it is only when these are abused that we oppose the intentions of Nature. From the existence of this intentional relation between mastication and the salivary secretion, the latter is always most copious in those creatures whose food requires con- tinued mastication. In ruminating animals, accordingly, the salivary glands are numerous and of great size, while they are at the same time so situated that the play of the muscles in the act of rumination communicates to them a proportionate stimulus. In those, again, which do not masticate at all, but swallow their food entire, there is scarcely any salivary secretion, and the glands appropriated to it are very small. Birds, and many fishes and reptiles, belong to the latter class. From the foregoing explanation of the object and con ditions of mastication, the reason will be apparent why fluids do not require to undergo that process, and also why dry, mealy substances stand in need of protracted chewing before they can be easily swallowed. When hot, spicy food is taken into the mouth the secretion of saliva is immensely increased, obviously for the purpose of diluting the excess of stimulant before it shall be allowed to reach the stomach. But when the food is of a mild and unirritating quality, much dilution is unnecessary, and-the secretion is accord- ingly moderate. The chief purpose of mastication, then, is evidently the minute division of the aliment, so as to admit of its being easily acted upon by the gastric juice when received into the stomach. Dr. Beaumont, however, seems to me to go too far in inferring, that " if the materia alimentaria could be introduced into the stomach in a finely divided state, the operations of mastication, insalivation, and deglutition would not be necessary." It would require a more exten- sive range of experiments than that which he has made, to prove that " aliment is as well digested and assimilated, and allays the sensation of hunger as perfectly, when in- troduced directly into the stomach (through an opening in' the side) in a proper state of division, as when the usual previous steps have been taken."* It is quite true that ♦ Experiments and Observations on the Gastric Juice and the Physiology of Digestion, by William Beaumont, M.D., of the United States Army, reprinted with Notes by Andrew Combe, M.D., Edin burgh, 1838. DEGLUTITION—THE GULLET. 61 mastication and deglutition are chiefly mechanical process- es ; but it is difficult to believe that so much care would have been taken to provide a proper supply of fluid of a constant and peculiar character like saliva, if water were capable of answering the purpose as well, and if saliva were useful only in lubricating the food. There subsists, moreover, between the sense of taste and the power of digestion a certain relation, which renders it more than probable that the active gratification of the former durino- mastication is favourable to the production and flow of nervous energy toward the stomach, and, consequently, in so far conducive to the healthy performance of digestion that even in that point of view insalivation could not easily be dispensed with. Dr. Beaumont's experiments, however, abundantly demonstrate that Monte"gre, and those who, along with him, consider the saliva as the principal agent in digestion, have not a shadow of foundation for their opinion. When unmasticated food is introduced into the stomach, the gastric juice acts only upon its surface, and changes of a purely chemical nature sometimes commence in its sub- stance before its digestion can be effected. Hence often arise, especially in children, those pains and troubles, that nausea and acidity, consequent on the continued presence of undigested aliment in the stomach. By a peculiarity of constitution, however, the stomach will not long retain food which it cannot dissolve. After a number ol hours —varying, according to the state of health, from one or two to ten, or even twenty—it is either rejected by vomit- ing, or transmitted unchanged to the intestine, where its presence irritates and gives rise to colic, flatulence, bowel- complaints, and, in delicate children, not unfrequently to convulsions. Hence another proof of the importance of slow and deliberate mastication. As soon as the morsel has been thoroughly masticated and impregnated with saliva, it is ready for transmission to the stomach. To this part of the process the term deglu- tition or swallowing is applied. Immediately at the back part of the mouth several pas- sages present themselves, leading in different directions—■ one upward and forward into the nose, another downward and in front into the-windpipe, and a third downward and behind into the oesophagus, gullet or meatpipe, and stomach, The last is the passage taken by the food ; and the violent 63 DEGLUTITION. coughing and occasional suffocation induced when it acci- dentally passes into the windpipe, are but a specimen of the serious evils which would be continually occurring if some provision were not made to obviate the danger, while the rarity with which such accidents actually happen, proves the almost unfailing efficacy of that which has been devised. The passage of the food into the nostrils is prevented by the interposition of a moveable fleshy curtain or valve hang- ing down from the palate, and visible at the back part of the mouth; this, in the act of swallowing, is stretched back- ward, so as to extend to the back part of the throat, and thus entirely shut up the opening into the nostrils. The passage into the windpipe, again, is protected by a cartila- ginous lid or covering called epiglottis, (from em, epi, upon, and y^urrtr, glottis, the tongue,) which projects backward from the. root of the tongue, and conducts the morsel over the glottis or opening of the windpipe. The epiglottis,. however, is greatly assisted in this operation by that rising upward arid forward of the gullet and windpipe to meet the morsel, of which we are conscious, and which can be felt by the hand in the act of swallowing, and the effect of which is in some degree to hide the glottis under the back- ward projection of the root of the tongue, and allow the morsel to drop past it into the gullet. Once fairly in the gullet, the course of the food into the stomach is easy enough. The gullet is simply a round tube, made up of two rows of muscular or fleshy fibres, the one longitudinal and the other transverse and circular, with a soft moist lining membrane to facilitate the trans- mission of its contents. When the morsel is introduced, its upper part contracts involuntarily, and pushes the mass downward ; the portion now reached contracts in its turn, and propels it farther; and so on in succession till it arrives at the stomach. Deglutition or swallowing is thus a more complicated operation than at first sight it appears to be. On looking at any person eating, one is apt to think that the morsel passes along the gullet into the stomach by its own weight; but we speedily perceive the error, when we recollect that, in the horse and the cow, for example, the mouth is on a level with the ground when feeding or drinking, and that the morsel or water is consequently propelled upward into the stomach against its own gravity. It is well known also, TARIETY OF SOURCES OF FOOD. 63 and often made a matter of public exhibition, that a man can swallow even liquids when standing on the crown of his head, with! the natural position of the stomach reversed. Deglutition is easier and quicker when the appetite is keen, and the alimentary bolus or morsel is moist and pro- perly softened. It is slow and difficult when the morsel- is dry and mealy, and the appetite nauseated. In vomiting, the action of the muscular fibres is inverted, or proceeds from, the lower end of the gullet toward the mouth ; and hence the object is carried upward instead of downward, as in the natural order. CHAPTER IV. ORGANS OF DIGESTION--THE STOMACH—THE GASTRIC JUICE. Surprising power of digestion—Variety of sources of food—All structures, however different, formed from the same blood—Ge- neral view of digestion, chymification, chyliflcation, sanguifica- tion, nutrition—The stomach in polypes, in quadrupeds, and in man—Its position, size, and complexity in different animals—Its , structure ; its peritoneal, muscular, and villous coats ; and uses of each—Its nerves and bloodvessels ; their nature, origins, and uses—The former the medium of communication between the brain and stomach—Their relation to undigested food—Animals not conscious of what goes on in the stomach—Advantages of this arrangement—The gastric juice the grand agent in digestion— Its origin and nature—Singular case of gunshot wound making a permanent opening into the stomach—Instructive experiment made by Dr. Beaumont—Important results. If, in the whole animal economy, where all is admirable, there be one operation which, on reflection, appears more wonderful than another, and which evinces in a higher de- gree the prodigious resources and power of the Creator in fashioning everything to His own will, it is perhaps that by which the same kind of nutriment is extracted from the most opposite varieties of food consumed by living beings. For, singular as it may appear, recent researches tend to establish the fact, that, eve(n in animals differing so widely in their aliment as the herbivorous and carnivorous quadru- peds, the ultimate products of digestion in both—the chyle and the blood—are identical in composition, in so far at least as can be determined by their chemical analysis.* Remarkable, .however, as this uniformity of result un- doubtedly is, it becomes still more striking when we con- template the variety of sources from which food is derived for the support of animal life. To use the words of an able » See Koget's Bridgewater Treatise, note at p. 58, vol. ii. 64 ALL STRUCTURES FORMED FROM THE BLOOD. writer already quoted, " There is no part of the organized structure of an animul or vegetable, however dense its tex- ture or acrid its qualities, that may not, under certain cir- cumstances, become the food of some species of insect, or contribute in some mode to the support of animal life. The more succulent parts of plants, such as the leaves or softer stems, are the principal sources of nourishment to the greater number of largeT quadrupeds, to multitudes of insects, as well as to numerous tribes of other animals. Some plants are more particularly assigned as the appro- priate nutriment of particular species, which would perish if these ceased to grow : thus, the silk-worm subsists almost exclusively upon the leaves of the mulberry tree ; and many species of caterpillars are attached each to a particu- lar plant, which they prefer to all others. There are at least fifty different species of insects that feed upon the common nettle ; and plants of which the juices are most acrid and poisonous to the generality of animals, such as euphorbium, henbane, and nightshade, afford a wholesome and delicious food to others."* Nor are the precision and accuracy with which the same fluid—the blood—affords to every structure of the body the precise species of nourish- ment or secretion which its elementary composition re- quires, however different each may be from the rest in chemical qualities, less admirable and extraordinary than its own original formation from such a variety of materials. To bone the blood furnishes the elements of bone with unerring accuracy ; to muscle the same blood furnishes the elements of muscle—to nerves the elements of nerve— to skin the elements of skin—and to vessels the elements of vessels ;—and yet, while each of these differs somewhat in composition from the others, the constituent elements of the blood by which they are furnished are everywhere the same. Similar phenomena, indeed, occur in the vegetable world; but this, instead of diminishing our wonder, tends rather to augment it. The same elements, extracted from the same soil, are converted into every variety of vegetable product__ into leaves of every shade of green, flowers of every form and tint, and juices of. every quality, from the deadly poison up to bland and life-supporting milk. Nay, even in the same plant—as in the poppy—we sometimes find the seeds * See Roget's Bridgewater Treatise, vol. ii., p. 59, GENERAL VIEW OF DIGESTION. 65 and the capsule which covers them endowed with the mest opposite properties. It would be very interesting to discover by what resources Nature thus effects the production of the same kind of nutritive fluid or chyle from so great a variety of substances, and apportions to every part the precise elements of which it stands in need ; but it is doubtful whether the human faculties were ever designed to penetrate so far into the modes of vital action, and, in the meantime, it will be better for us to confine our attention to that branch of the inquiry which we can easily comprehend, and which bears a direct reference to our own welfare. We know already that certain organs are concerned in the processes abovemen- tioned, and that these organs act under the regulation of certain general laws. If we make ourselves acquainted with, and carefully fulfil, these laws, we reap a rich reward in the enjoyment of sound and vigorous digestion. Where- as, if, either from ignorance or from carelessness, we neglect their fulfilment, we bring upon ourselves a severe punish- ment in the form of dyspeptic or nervous disease. As- suredly, then, alternatives like these ought to excite some desire for information in the minds even of the most indif- ferent. Before, however, commencing a description of the organs concerned in digestion, it will be useful to take a general view of the different stages of preparation through which the food passes, between its reception into the stomach and its assimilation, or ultimate conversion into a constituent part of the animal body, and becoming endowed with the properties of life. The reader will thus be better enabled to understand the meaning of various terms and expres- sions, the frequent use which it is almost impossible to avoid, even in the beginning of our exposition. When the food is received into the stomach, it is there subjected to the action of a solvent fluid, called the gastric or stomach juice, (from yaarrjp, gaster, stomach,) by which it is gradually converted into a soft grayish and pultaceous mass, called chyme, {from xvp°Ci chymos, humour or juice ;) whence the process is called chymification, or chyme-making. The chyme, as fast as it is formed, is expelled by the con- tractile power of the stomach into the duodenum, (from duodenus, consisting of twelve, because it is supposed to ba about twelve inches long,) or first portion of the intestines, 66 GENERAL VIEW OF DIGESTION. It there meets with the bile from the liver, and with the pancreatic juice, which very much resembles the saliva, from the. pancreas or sweet bread, {nag, pas, all, and icptag, kreas, flesh, it being of a fleshy consistence,) a large gland which lies across the spine a little below the stomach, and is marked P in the wood-cut given in the chapter on Chy- lification. By t?he action of these two fluids the chyme is converted into two distinct portions—a milky white fluid named chyle, {from x^og chylos, chyle,) and a thick yellow residue. This process is called chylification, or chyle-ma- king. The chyle is then sucked in by absorbent vessels, extensively ramified on the inner membrane or lining of the bowels, and sometimes named, from the white colour of their contents, lacleals or milk-bearers, (from lac, milk.) These lacteals ultimately converge into one trunk, named the thoracic duct or chestpipe, (from its course lying through the thorax or chest,) and which terminates, as will be seen in a cut in Chapter VI., in the great vein under the clavi- cle or collar-bone, hence called subclavian vein, just before the latter reaches the right side of the heart; and there the chyle is poured into the general current of venous blood. But although thus mingled with the blood, the chyle is not yet sufficiently capacitated for its duties in the system. To complete its preparation, it still requires to be exposed to the action of the air during respiration. This is accord- ingly done by its passing through the lungs along with the dark and venous blood, which stands in need of the same change. In the course of this process both the chyle and the venous blood are converted into red, arterial, or nutritive blood, which is afterward distributed by the heart through the arteries, to supply nourishment and support to every part of the body. Hence the change which t3kes place in the lungs is properly enough named sanguification, or blood-making. * The thickish yellow residue left in the duodenum after the separation of the chyle from the chyme, is that portion of the food which affords no nourishment, and which, after traversing the whole length of the intestinal canal, and undergoing still farther change, is thrown out of the body in the shape of faces or excrement. But in this course its * For a full explanation of the nature, importance, and laws of respiration, see the author's Principles of Physiology, &c., 10th edi. tion, chap. iz. STOMACH IN THE LOWER ANttfALS. 6? bulk is increased and its appearance changed, by the addi- tion of much waste matter, which, having already served its purposes in the system, is at last, as will be afterward shown, thrown out by the same channel. With this general view of the nature of Digestion before us, we can now examine more satisfactorily the structure and mode of action of each of the organs concerned in effecting it. Chymification being the first step in the com- plicated process, we shall begin with the organ by which it is performed, namely, the Stomach. In the lowest'class of animals—the hydra, for example, which belongs to the order of gelatinous polypi, and abounds in stagnant pools—the stomach is like a simple bag, devoid of any peculiar organization ; or, more properly speaking, the animal itself is nothing more than a living stomach ; for the minutest inspection can discover in it no trace of anything like vessels, nerves, brain, lungs, heart, or other known organ. Even the experienced eye of Cuvier, aided by a powerful microscope, could detect in their structure nothing more than a transparent parenchyma, full of darkish grains or points, and offering no trace of any distinguisha- ble organs.* In form the animal somewhat resembles the finger of a glove, the hollow in the centre being appropri- ated for the reception of its food ; and yet, with all this simplicity of structure, it not only moves and swims, but seizes its prey by means of its tentacula, thrusts it into its cavity, and digests it visibly—" d vue d'ceil." And what is still more strange, when it is turned inside out, the surface which was formerly the exterior of the body, now digests as actively and efficiently as if it had never served any other purpose. Bloodvessels being merely pipes serving for the convey- ance of nourishment from the place where it is stored up and prepared, to those more distant parts which stand in need of it, it is obvious that in animals of this very simple description, where every part of the internal surface of the body is already in immediate contact with its food, and itself imbibes or absorbs directly all the nourishment which it requires, they would be entirely superfluous, and accord- ingly none are to be found. Owing to this extreme simplicity of organization, a hydra may be cut into pieces, each of which will become a per- » Cuvier's Regne Animal, vol. ii, p. 296. 68 THE HUMAN STOMACH DESCRIBED. feet animal. But in proportion as we ascend in the scale of creation, the organization becomes more complicated, and the functions more numerous and also more dependent on each other; so that, when we arrive at man—the highest of all—we find that the loss or injury of any vital organ puts a stop to, or impairs, the action of all the rest. It is impossible, however, in an elementary work like this, to trace the gradation through the different series of animals. We must confine our examination to man, and only borrow from other creatures such illustrations as may be necessaij" for throwing light upon the human structure. THE STOMACH. 69 In man, then, the stonwch is a large membranous and jnuscular bag, lying under the convexity of the lower ribs of the left side, and stretching toward the right a little be- yond the hollow commonly called the pit of the stomach. In shape it somewhat resembles the bag of a bagpipe, as will be seen from the annexed figure ; its left or larger extremity being in contact with the ribs, and its right or narrow extremity situated under the pit of the stomach. The position of the stomach (Stm.) relatively to the chest, bowels, and liver, will be understood by inspecting the figure on the preceding page. It is separated from the cavity of the chest by the diaphragm or midriff DD, with which its upper surface is in immediate contact, and through which the gullet passes to enter its left extremity. Its right or pyloric extremity, marked P in the subjoined cut, lies close to the lower surface of the liver, (Livr.,) the latter being a little displaced to show its situation. On the lower surface it has the appearance of resting on the intes- tines, as if imbedded among their folds. The parts of the stomach which have received names and require to be noticed, are—the cardiac orifice, (marked C in the following figure, and so named from being near the Ktap, hear, or heart,) in which the gullet terminates, and ^ through which food and drink are introduced ; P, the pylo- 70 THE STOMACH VARIES IN SIZE. rus, or pyloric orifice, (from irvlopog, pyloros, a gatekeeper, because it allows none but digested food to pass out.) where the intestine called the duodenum begins, and through which the chyme passes after digestion is completed, and which, when the stomach is full, is nearly on a level with the cardia, although when empty it is lower; SS, the smaller arch or curvature ; and GGG, the greater arch or curvature. The spleen is attached to that part of the larger arch marked with dotted points. From the situation of the cardia 0, and its connexion with the gullet, it will be at once perceived that this forms one of the points of attachment by which the stomach is retained in its place. In size the stomach varies much in different individuals, as well as in different animals, according to the bulk and quality of their food. As a general rule, it is larger among the labouring poor than among the rich, as the former re- quire a larger quantity of their inferior food to obtain from it an equal amount of nourishment. For the same reason, animals which subsist on vegetable substances have a very capacious stomach, while those subsisting on animal or concentrated food have it simple and small. In man its capacity may be diminished or augmented within certain limits, by corresponding modifications of diet. In some gluttons, and in cases of diseased appetite, it has been found of enormous dimensions; but this rule does not always hold, for the stomach is sometimes smaller than usual in immoderate eaters, and then its contents pass through only partially digested. In accordance with this relation between the capacity and structure of the organs of digestion and the quality of food, the stomach and intestines are found to be very small and short in carnivorous quadrupeds and birds of prey, which are intended to live on concentrated aliment. The same is the case with the granivorous or grain-eating birds, as their food also is contained in a small bulk. But in herbivorous animals—in the food of which the nutritive principle forms a very small proportion of the whole, per- haps not one-twentieth, and which, consequently, require a large bulk of it for their sustenance—the digestive appara- tus is on a large scale, as any one may conceive in a mo- ment, by comparing the portly protuberance of the cow with the lank paunch of the greyhound. The cow, in fact Is little else but a living laboratory for the conversion of STOMACH IN ■CMINATING ANIMALS. 71 vegetable into animal matter; and accordingly, not only is its stomach large and complex, but its intestinal canal is nearly twenty-four times the length of its body ; whereas, in some carnivorous animals the whole intestine does not exceed once their own leno-th. In ruminating animals, such as the sheep and ox, the stomach, as will be seen from the annexed figure, not only is large, to adapt it to the bulky nature of their food, but is complicated in its structure, to fit it for effecting the great changes which vegetable aliment requires to undergo before it can be converted into blood. It may indeed be said to consist of four distinct stomachs conjoined. In the first of these, AA, termed the paunch, the herbage is de- posited when first swallowed after hasty and ineffectual mastication. It there undergoes a kind of maceration or sleeping in a fluid provided for the purpose ; after which it passes from the paunch into a smaller bag, called the reti- culum, or bonnet, B, which, in some animals, such as the camel and dromedary, is designed exclusively as a reservoir for water, which being there stored up in large quantities, ready for use when wanted, fits them in a wonderful man- ner for travelling through the arid deserts where no water is to be obtained, and where, without some such provision, they would of course soon perish. So admirably is the re- ticulum adapted for this special purpose, that the water con- tained in it undergoes little or no change either in quality 72 STOMACH IN GRAIN-EATING BIRDS. or quantity, although if it were collected in the ordinary digesting stomach, it would be entirely absorbed in the course of a few minutes. It is not even mixed with the food which is swallowed after it, as the animal has the power of directing solids at once into the other cavities. From the reticulum the alimentary mass is again returned to the mouth, there to be thoroughly masticated and mixed with the saliva; after which it descends a second time through the gullet: but, instead of passing, as before, into the paunch, it enters the third bag, omasum, or many-plies, C, where it undergoes farther changes, and is then trans- mitted to the fourth portion, D, adjoining the pylorus, and named ab-omasum, or red-bag. The last portion is exactly similar in structure and in function to the simple stomach of man and the other mammalia, and is, in fact, the true stomach, the other three being merely preparatory organs. The first part of the process, by which the food is taken hastily into the paunch and afterward sent back to the mouth in detached portions for farther mastication, is called rumination or chewing the cud, and those species which perform it are thence called ruminating animals. Sheep and cows may be seen lying ruminating in pasture- fields after having cropped as much herbage as fills the paunch ; and feeding is thus rendered to them a source of prolonged enjoyment. In those birds, again, which live on hard grain and seeds, and possess no organs of mastication wherewith to bruise , or grind them down, another modification of the digestive apparatus is found. ' Nature has furnished them with a membranous bag, called a crop or craw, into which trie food is received, and where it is slightly softened by a mucous fluid secreted from the surface of the bag. Thus prepared, it is transmitted into an organ analogous to the stomach of other animals, and called the gizzard, which has a very singular structure. Its walls are composed of four distinct portions of thick tough muscular substance, a large one at each side of the cavity and a small one at each end. The inner surface of the muscle is lined with an extremely callous cuticle, approaching in hardness to cartilage or horn. When the moistened grain is introduced into the gizzard from the crop, the muscular walls of the gizzard enter into powerful action, and, by their alternate contraction and relaxation, bruise the grains as between STRUCTURE OF THE STOMACH—COATS OF THE STOMACH. 73 two grindstones. In some birds their action is assisted by a quantity of small gravel, purposely swallowed along with the food ; and it is well known to seamen that poultry never thrive on a voyage, however well they may be fed, if gravel or coarse sand, as well as food, be not placed within their reach. Mr. Hunter has counted as many as a thousand small stones in the gizzard of a common goose.* The astonishing force with which the muscles of the gizzard act, and the resistance of its lining membrane, may be conceived from the experiments of Spallanzani and Reaumur, who compelled geese and other birds to swallow needles, lancets, and other sharp metallic bodies, and, on afterward killing them, regularly found the points broken off and the edges blunted, without any injury having been sustained by the gizzard itself. In structure, the stomach of both man and animals consists of three membranous layers or coats, of follicles or glands, and of numerous bloodvessels and nerves. The first or external layer is the smooth, glistening, whitish membrane, which is familiar to all who have ever seen an animal opened, or a fowl drawn for cooking. It is a fold of the tough shining membrane called peritoneum, (frorn nepireivu, periteino, I extend round,) which lines the abdomen, and constitutes the outer covering of all the ab- dominal organs. Its use is obviously to strengthen the substance of the stomach, to assist in binding down this and the other organs in their respective situations, and, by the smoothness and constant moisture of their surfaces, to enable them to move upon each other, and adapt them- selves freely to their different states of emptiness and dis- tention. The second, middle, or muscular coat consists of fleshy fibres, one layer of which, running longitudinally from the cardia to the pylorus, seems to be a continuation of the longitudinal muscular fibres of the gullet: another runs in a circular direction, embracing, as it were, the stomach from one curvature to the other, and constituting what are called the transverse fibres. A third and more internal layer of this coat, is spoken of by Sir Charles Bell as a * The above descriptions and figure are taken, with slight alt i ra- tions, from the Treatise on Animal Physiology in the Librar/ of Useful Knowledge. 7 74 COATS OF THE STOMACH. continuation of the circular fibres of the gullet, whici divide into two parcels, the one distributed over the left or larger end, and the other over the pyloric or narrower end. *The uses of the muscular coat have, as we shall after- ward see, a direct reference to the special function of diges- tion. By the joint action of its longitudinal and circular fibres, the stomach is enabled to contract, and shorten its diameter in every direction, so as to adapt its capacity to the volume of its contents ; while, by their successive ac- tion, or alternate contraction and relaxation, a kind of churning motion is produced, which contributes greatly ta digestion by the motion which it imparts to the food, and the consequent exposure which it effects of every portion of it in its turn to the contact of the gastric juice. The force and rapidity of these muscular contractions are modified by the more or less stimulant nature of the food', the state of health,exercise, and other circumstances -T but, according to Dr. Beaumont, the ordinary direction in which they take place, and the course which they im- part to the food, are as follows : The alimentary bolus or morsel, on entering the cardiac orifice, turns to the left, follows the line of the great cur- vature of the stomach toward the pylorus, returns in the line of the smaller curvature, makes its appearance again at the cardia, and then descends, as before, to the great curvature, to undergo similar revolutions till digestion be completed. Each revolution occupies about from one to three minutes, and its rapidity increases as chymification advances. In treating of muscular action in the former volume, I pointed out (p. 122) the necessity of the co-operation of a nervous stimulus to produce the result; and remarked that there are two kinds of muscles, one called the volun- tary, which contract at the command of the will, and the other the involuntary, over which the will has no control, and which act only in obedience to their own peculiar sti- muli. Of the latter description are the muscular fibres of the stomach. They contract when the stimulus of food is applied to them, but we can neither contract nor relax them by an effort of the will, nor are we even conscious of their existence. It is, indeed, fortunate for us that the necessary motion* MUCOUS COAT OF THE STOMACH. 75 «oT the stomach are not intrusted to our guidance, like those of the hand or foot. Supposing that we were to eat three meals a day, the digestion of each requiring three or four hours—and that its management depended entirely upon our superintendence—our whole attention would be required to the process, to the exclusion of every other duty, for ten or twelve hours a day ; and every time that our thoughts wandered for a few minutes, digestion would stand still, and the stomach be disordered by the chemical decomposition of the food which would ensue, so that it would be impossible for us to dedicate any time either to business or to social enjoyment. But from all these in- conveniences we are entirely freed, by the stomach being placed under the dominion of the involuntary nerves, and so constituted as to perform its functions without any aid from our will. The third and innermost coat, called the mucous or vil- lous, is that smooth, unequal, velvety membrane, of a red- dish white or pale pink colour, which lines the internal surface of the stomach. From being of much greater ex- tent than the other two coats, its surface is thrown into ruga, plica, folds, or wrinkles, which are simple in man, but very marked in some animals, as seen familiarly in tripe. The subjoined wood-cut, from the Library of Use- ful Knowledge, will give some notion of their appearance. Near the pyloric orifice the villous coat is doubled on itself, lous coat is constantly covered with a very thin transpa- rent viscid mucus, and its folds are always best seen in fthose who die suddenly. After disease when the stomach is relaxed, they frequently disappear. 78 N1RVE3 AND BLOODVESSELS OF THE STOMACH. In addition to the folds just described, the mucous coat contains a great number of spheroidal glandular bodies or follicles, some of them scarcely larger than pin-heads, which lie immediately beneath and almost incorporated with it, and which are most numerous near the pylorus. Physiologists are not entirely agreed whether the fluid se- creted by these follicles be the gastric juice, or merely the mucus already referred to as lubricating the internal sur- face of the stomach. The latter, however, is the opinion generally entertained, and the one which is supported, as we shall afterward see, by the strongest evidence ; the gastric juice being, in fact, secreted directly from the ca- pillary or hair-sized vessels in which the minute branches of the arteries terminate. Of the nerves and bloodvessels supplying the stomach it is unnecessary to say much. We shall afterward have occasion to notice the former at some length, and to the general reader the origin and distribution of the blood- vessels are as unimportant as they would be difficult of comprehension; for the nature of the red blood is the same by whatever artery it is supplied, and that of the dark blood the same by whatever vein it is returned to the heart. All that it is important to know is, that the sto- mach receives a large supply of blood by means of nume- rous bloodvessels, the principal of which, as represented on the wood-cut at page 69, follow the course of GG the greater and SS the smaller curvatures, and send off innu- merable small branches as they proceed to every part of the stomach. The coronary artery and the pyloric branch* of the hepatic or liver artery go to the smaller curvature, while another branch of the hepatic, and one from the sple- nic or spleen artery, are ramified on the larger curvature. In determining the uses of the internal or villous coat of the stomach, we must begin by considering separately that of each of the elementary structures of which it is composed—its follicles, bloodvessels, and nerves—and the nature of the peculiar secretion, the gastric juice, to which it gives rise. The follicles pour out the bland viscid mucus which lubricates the internal coat, and protects it in some degree from sustaining injury by the immediate contact of irritating bodies. When the follicles are diseased, as in what is called water-brash, they sometimes throw out a large quan, BLOODVESSELS of the stomach. 77 lity of a ropy transparent fluid, which oppresses the stomach and impairs digestion. The bloodvessels of the stomach, like those of every other part, are more or less active according to the energy of its functions at the time. In treating of the laws of exer- cise as applicable to all living parts,* I took considerable pains to point out the relation which the Creator has established between the activity of every organ and the energy of its vital functions. When the brain is exercised and the mind active, an augmented flow of blood takes place toward it to support its increased action, of which the throbbing temples and fiery complexion of a man in a paroxysm of rage are familiar examples. When it is inac- tive and the mind indolent, a diminished flow of blood occurs. In like manner, when the muscles are called into vigorous action, the circulation of the blood through them is quickened, and their nerves are more than usually ex- cited : greater waste of material is caused by the increase of activity, and more blood, consequently, is required to repair the waste and sustain their tone. This law was so well known to the older writers, that it was announced by them as an axiom in the very comprehensive phrase, Ubi stimulus, ibi affluxus—" Wherever a stimulus is, there is also an afflux." The stomach forms no exception to this general law of the animal economy. When it is empty and idle, it is contracted upon itself into comparatively small bulk, and its bloodvessels become shortened and tortuous in a corres- ponding degree. The result is both a diminution of their calibre and a slower circulation through their branches. But when the stomach is full and active the bloodvessels have free scope, their tortuosity disappears, their diameter enlarges, and the circulation through them becomes quicker, and fit for the rapid secretion of the mucous and gastric fluids in the quantities which we have seen to be required for the fulfilment of digestion. Accordingly, when the latter process is going on, the small arterial branches ramified on the mucous coat of the stomach become so multiplied and distended, as to impart to it a deeper red colour than it has when the stomach is empty. The in- creased afflux of red or arterial blood to the stomach during digestion is not merely inferred from the analogy of other * Principles of Physiology, 10th edition, &c, pp. 153, 192, and 302. 7* 7S NERVES OF THE STOMACH. organs. Many opportunities have occurred of ascertaining" the fact; and, as I shall have occasion to mention, Dr. Beaumont very often saw it take place. A corresponding change occurs in the veins of the sto- mach during digestion. Their diameter becomes enlarged, their course more straight, and the current of blood through: them more rapid. As the minute or capiUary extremities of the arteries open upon the inner surface of the stomach, and there exhale a fluid secretion, so the corresponding venous capillaries likewise open upon the same surface, and inhale or absorb fluid, which they carry into the general circulation. The rapidity with'which this absorption some- times takes place is almost incredible ; for a large draught of water may be thus taken up in a few minutes. Fluids mixed with camphor or other strong-scented substance have been given to animals as an experiment, and, on killing them shortly afterward, the peculiar smell has been detected in the blood. Most liquids are thus not digested, but simply absorbed. Rapid, however, as the process is, poisons which enter the system by absorption do not act by any means so in- stantaneously as those which directly affect the nervous system. In regard to the peculiar influence which each of the nerves ramified on the stomach exercises on its functions, much difference of opinion still prevails. We may, how- ever, gather some useful notions by adverting to the diffe- rent sources whence they are derived, and comparing these with the purposes for which we know from analogy that different kinds of nerves are required. Strictly speaking, the nervous filaments supplied to the stomach proceed from three distinct sources, and may be held to fulfil as many distinct uses. In apparent accordance with this, we observe three, if not four, distinct classes of operations going on in that organ, each of which may, from analogy, be presumed to require a distinct nerve for its performance. These are, first, the pleasurable conscious- ness attendant on the presence of wholesome food in a healthy stomach, and which becomes painful and disagree- able when the stomach is diseased or the food of improper quality; secondly, the peristaltic or muscular motion which commences the moment food is swallowed, and continue* till digestion is completed ; and, lastly, the different pro* DIFFERENT USES OT THE STOMACHIC NERVES. 79 Cesses of circulation, nutrition, secretion, and absorption, which go on in the component tissues of the stomach and support its life. To these ought perhaps to be added the sensation in which the feeling of appetite originates, and which we have already seen to be connected with the pneumogastric nerve. But as it is still uncertain whether it and the first of the three now named may not be modifi- cations of the same thing, I shall not insist on considering them as different. Although we cannot state positively what particular nerve presides over each of these functions, it may be mentioned that strong presumptive evidence has been adduced, particularly by Brachet, to show that the pneumo- gastric* nerve is charged with the involuntary motions of the stomach, as well as with the sense of its condition. Food being the natural stimulus of that organ, as light is of the eye, its presence alone, without and even against the will, suffices to produce the contraction of its muscular coat; and, accordingly, the more stimulating the food, the more rapid and vigorous is the muscular contraction which it excites. So far, indeed, do the stomachic nerves respond to their own stimuli, that, if nauseous or other irritant and indigestible substances be swallowed, the action of the muscular coat becomes so violent as to excite sympatheti- cally the simultaneous contraction of the diaphragm and abdominal muscles, to aid in their immediate expulsion by vomiting; and this is the reason why such substances are in common use as emetics. Magendie doubts whether these movements are in any measure dependent upon nervous influence ; but the fact of their being so seems to be proved by the experiments of Gmelin and Tiedemann, who found them constantly pro- duced when the pneumogastric nerve was irritated either by the scalpel or by the contact of alcohol. Brachet also, who examined the subject with great care, obtained similar results ; and the only plausible argument against their conclusiveness consists in the double function which seems thus to be assigned to a single nerve—that of conveying to the brain a sense of the state of the stomach, and that of imparting motion to its muscular fibres. Brachet, however, turns this charge into an additional proof; for, on careful * From nvevpov, pneumon, a lung, and yaorep, gaster the sto- mach, or lung and stomach nerve. 80 USES OF THE PNEUMOGASTRIC NERVE. dissection, it appears that the pneumogastric nerve is really a compound of two distinct sets of fibres, intimately connected no doubt in structure and in function, but each essentially distinct in its origin, and so far fitted for a peculiar office. When the pneumogastric or chief nerve of the stomach is tied or cut through, and its ends separated so as to interrupt the flow of nervous energy toward that organ, digestion is either entirely arrested or greatly impaired. By the greater number of physiologists this result is considered to arise from the consequent stoppage of that gentle and continued agitation of the alimentary mass in the stomach which is necessary for its thorough impregnation with the gastric juice, and which we have seen to depend on a stimulus communicated to its muscular coat by that nerve. By some, however, this explanation is regarded as incorrect. Magendie and Dr. Holland, for example, say that they have sometimes observed digestion continue even after the division of the nerves ; and that, when it is retarded or impaired, the result arises only from the troubled state of respiration which the cutting of the nerve induces at the same time. To this, again, it is answered, that Dupuytren has divided the nerve below the part where the pulmonary branches are given off, and, consequently, left respiration unimpaired ; but that still digestion was arrested, provided a portion of it was cut out so as not to allow the current of nervous influence to continue : for if the two ends of the nerve be left nearly in contact, it appears that little interruption of its action takes place. Here, however, I cannot help observing, that, in drawing conclusions from experiments of this nature, the constitu- tional disturbance inseparable from the infliction of exten- sive wounds on living animals is seldom taken sufficiently into account. As regards digestion, for example, it is not to be expected that that function can be carried on with all the regularity of health when the animal is suffering severe pain, even although the stomach be left untouched. Brachet, indeed, has shown, by direct experiment, that digestion may be interrupted almost as effectually by making an incision on the side or thigh, (provided it be sufficiently deep and painful to excite constitutional disturbance,) as by cutting the pneumogastric nerve itself. This being the case, we must not be loo hasty in considering every appa- USES OF THE PNEUMOGASTRIC NERVE. 81 rent result as inseparably and exclusively connected with the individual injury under our notice at the time ; we must repeat our observations under every variety of cir- cumstances, and be careful to separate the accidental from the essential, before admitting the inference to be correct. It is, in fact, this unavoidable source of vagueness which so often renders experiments on living animals as incon- clusive as they are inherently cruel. But after making every allowance on this account, the experiments on digestion have been so frequently repeated and so extensively varied, that the general results already noticed may safely be regarded as demonstrated. On all hands, accordingly, the necessity of the co-operation of the nervous energy in effecting it is admitted ; for no one se- riously denies the fact, that retardation or total cessation of digestion ensues, when the flow of the nervous fluid to- ward the stomach is prevented by the division and separa- tion of the cut ends of the pneumogastric nerve, or by the operation of narcotics and the other disturbing causes already alluded to. It is true that the mode in which the nerve acts is not yet ascertained, although the fact of its neces- sary co-operation is rarely disputed. As, however, the di- rection of a current of galvanism to the cut end of the nerve next the stomach suffices to re-establish digestion after that process has been suspended by the interruption of the ner- vous influence consequent on its division, we may reason- ably infer that, in the healthy state, the nerve merely trans- mits to the stomach a stimulus or energy generated for the purpose either in the brain or in the spinal marrow and ganglia—that the nerve, in short, acts only as a condutor, and does not originate the influence which it evidently imparts. In several of Brachet's cases, indeed, as well as in those of Tiedemann, the continued irritation of the cut end of the nerve proved sufficient to carry on digestion to a certain point, by affording, in another way, the necessary stimulus to the muscular contractions of the stomach : for in all these experiments digestion was found to have ad- vanced almost in exact proportion to the degree of admixture which had been effected of the food with the gastric juice —an admixture now ascertained to be produced chiefly by the contractile power of the stomach itself. The muscular contractions of the stomach being thus under the guidance of the pneumogastric nerve, what are 82 USES OF THE SYMPATHETIC NERVE. called its vital functions—those by which its life is sustain- ed—viz., circulation, nutrition, secretion, and absorption, are generally considered to be carried on under the influence of the great sympathetic or ganglionic nerve, so called from its v«ry extensive ramifications being supposed to bring the different parts of the system into relation with each other, and which, accordingly, is found to exist in animals that have neither brain nor spinal marrow, nor nerves of volun- tary motion. In man, however, the sympathetic nerve' receives filaments from the sentient or feeling part of the spinal marrow, probably for the purpose of connecting more intimately the organic with the higher functions of animal life. But as much obscurity still prevails on this subject, and, moreover, we have no direct control over the action of the ganglionic nerves, I shall not detain the reader with any conjectural discussion, but rather request his attention for a moment U the circumstance that it is through the medium of the nervous communications above hinted at that the very remarkable influence which all must have experienced and observed as constantly exerted by the mind and sto- mach on each other, is kept up—an influence so powerful in its effects on both bodily and mental health, as to require special notice when we shall treat of the practical applica- tion of the present exposition. The importance of the nervous agency in effecting diges- tion has been denied, because we are not conscious of the presence of food in the stomach. B ut in health the want of such consciousness is aprivilege, and not a defect; and it has been admirably pointed out by Dr. Southwood Smith* that, in possessing, as we do, the distinct consciousness of a pleasurable feeling in the stomach after indulging in a suitable meal, we have all that is desirable for either utility or enjoyment. If we were aware of the presence of every portion of food v/hiph the stomach contains, and of the changes occurring in each, our attention would be so dis- agreeably and unprofitably taken up, that we would pray to be delivered from the annoyance. Where, however, from disease or the food being inappropriate, the stomach is in- jured by what is eaten, consciousness then becomes pain- ful for the express purpose of warning us that mischief has been done, and that we must take means for its removal. In some kinds of dyspepsia, indeed, the sensibility becomes » Philosophy of Health, voL i., p. 80. RELATION OF NERVES TO UNDIGESTED FOOD. "83 exalted to an extraordinary degree. Barras, who suffered intensely from this cause, says of himself '• the sensibility of the stomach increased to a surprising extent ; instead of organic it became animal, to use the expression of Bichat. Everything which took place in the principal organ of di- gestion became as palpable to sense as if it had taken place on the organ of touch, and the presence of aliment was per- ceived as clearly as if it had been under my hand."* The nerves of the stomach, it ought to be remarked, have a direct relation to undigested but digestible substances ; or, in other words, undigested food forms their natural and appropriate stimulus. In consequence of this arrangement, when any body incapable of digestion is introduced into its cavity, distinct uneasiness is speedily excited, and an effort is soon made to expel it either upward by the mouth or downward by the bowels. It is in this way that bile in the stomach excites nausea, and that tartar emetic produces vomiting. The nerves of the bowels, on the other hand, are constituted with relation to the presence of digested food, and, consequently, when anything escapes into them from the stomach in an undigested state, it becomes to them a source of irritative ex«itement; and hence the colicky pains and bowel-complaints which so commonly attend the pas- sage through the intestinal canal of such undigestible sub- stances as fat, husks of fruits, berries, and cherry-stones. Such, then, are the component parts of the stomach, and such the uses which they individually fulfil ; but before we can consider them in their combined form, there is still another agent, and an important one in digestion, which has already been repeatedly named, and which, though not a portion of the stomach, yet plays too conspicuous a part in its operations not to require some separate notice—the gas- tric OR STOMACH JUICE. The existence of a solvent fluid in the stomach has long been known and its uses suspected ; but for our first accurate acquaintance with its propensities and mode of action we are indebted chiefly to the sagacity and persevering zeal of Spallanzani, who investigated the subject with great care and success about the middle of last century. Con- sidering the peculiar difficulties by which the inquiry is surrounded, it i3 offering no trifling homage to that distin- guished observer to say, that, by means of numerous, varied, * Cyclop. Pract. Med., voL ii., p. 635. 84 SINGULAR CASE OF WOUND IN THE STOMACH. and well-devised experiments on man and animals, he succeeded in overcoming most of the obstacles which had baffled the ingenuity of his predecessors, and in obtaining results, the general accuracy and importance of which are now appreciated more and more highly, in proportion as our knowledge advances and opportunities present them- selves of bringing them to the test of experience. It is rarely, indeed, that we can actually see what is going on in a healthy stomach ; but in a few instances this advan- tage has been enjoyed, and turned to account in investiga- ting the phenomena of digestion. By far the most instruc- tive example of this kind which has ever occurred, came under the observation of Dr. Beaumont of the American army ; and as that gentleman eagerly embraced the oppor- tunity so unexpectedly afforded him of testing the prevailing doctrines by a series of experiments, continued during a period of several years, and under various conditions of health and external circumstances, I shall so frequently have occasion to refer to his observations, that it will be useful to give a brief outline of the case before entering farther upon the subject, in order that the reader may be enabled to judge for himself what weight is due to Dr. Beaumont's evidence on any disputed point. Dr. Beaumont, while stationed at Michillimackinac, in the Michigan territory, in 1822, in the military service of the United States, was called upon to take charge of Alexis St. Martin, a young Canadian of eighteen years of age, good constitution and robust health, who was accidentally wounded by the discharge of a musket on 6th June, 1822. " The charge," says Dr. Beaumont, " consisting of pow- der and duck-shot, was received in the left side, at the distance of one yard from the muzzle of the gun. The contents entered posteriorly, and in an oblique direction, forward and inward ; literally blowing off integuments and muscles to the size of a man's hand, fracturing and carrying away the anterior half of the sixth rib, fracturing the fifth, lacerating the lower portion of the left lobe of the lungs, the diaphragm, and perforating the stomach." On the fifth day sloughing took place ; lacerated por- tions of the lung and stomach separated, and left a perfora- tion into the latter, " large enough to' admit the whole length of the middle finger into its cavity ; and also a pas- sage into the chest half as largo as his fist.'" Violent fever LEAVIKG A PERMANENT OPENING INTO ITS CAVITY, 85 and farther sloughing ensued; and for seventeen days everything swallowed passed out through the wound, and the patient was kept alive chiefly by nourishing injections. By and by the fever subsided, the wound improved in ap- pearance, and after the fourth week the appetite became good, digestion regular, the evacuations natural, and the health of the system complete. The orifice, however, never closed; and at every dressing the contents of the stomach flowed out, and its coats frequently became everted or protruded so far as to equal in size a hen's egg, but they were always easily returned. The above figure exhibits the appearance of the wound after it was healed. The circumference of the wound, E E E L, extended to about twelve inches ; and the opening into the stomach, AAA, nearly in its centre, was about two inches below the left nipple F. The folds of the villous coat are visible at B C. Some months after, St. Martin suffered extremely from the death and exfoliation of portions of the injured ribs and their cartilages, and his life was often in jeopardy ; but, through the skill and unremitting care with which he was treated by Dr. Beaumont, he ultimately recovered, and in 86 SINGULAR CASE OF WOUND IN THE STOMACH, April, 1823, was going about, doing light work and rapidly regaining strength. On 6th June, 1823, a year from the date of the accident, the injured parts were all sound, except the perforation into the stomach, which was now two and a half inches in cir- cumference. For some months thereafter the food could be retained only by constantly wearing a compress and bandage; but early in winter a small fold or doubling of the villous coat began to appear, which gradually increased till it filled the aperture and acted as a valve, so as com- pletely to prevent any efflux from within, but to admit of being easily pushed back by the finger from without. Here, then, was an admirable opportunity for experi- menting on the subject of digestion, and for observing the healthy and undisturbed operations of nature free from the agony of vivisections, and from the sources of fallacy in- separable from operating on animals. Dr. Beaumont was sensible of its value, and accordingly pursued his inquiries with the most praiseworthy perseverance and disinterested- ness. Having been fortunate enough to obtain a copy of his work, I shall not hesitate to make free use of its contents. Dr. Beaumont began his experiments in May, 1825, and continued them for four or five months, St. Martin being then in high health. In the autumn St. Martin returned to Canada, married, had a family, worked hard, engaged as a voyageur with the Hudson's Bay Fur Company, remain- ed there four years, and was then engaged, at a great ex- pense, by Dr. Beaumont to come and reside near him on the Mississippi, for the purpose of enabling him to complete his investigations. He came accordingly in August, 1829, and remained till March, 1831. He then went a second time to Canada, but returned to Dr. Beaumont in Novem- ber, 1832, when the experiments were once more resumed, and continued till March, 1833, at which time he finally left Dr. Beaumont. He now enjoys perfect health, but the orifice made by the wound remains in the same state as in 1824. Dr. Beaumont describes the aperture in St. Martin's sto- mach as being situated about three inches to the left of the cardia, near the left or superior termination of the oreat curvature. When the stomach was nearly empty, he was able to examine its cavity to the depth of five or six inches by artificial distention. When it was entirely empty, the stomach was always contracted on itself, and the valve LEAVING A PERMANENT OPENING INTO ITS CAVITY. 87 generally forced through the orifice, together with a portion of the mucous membrane equal in bulk to a hen's egg. After sleeping for a few hours on the left side, the protruded portion became so much larger as to spread " over the neighbouring integuments five or six inches in circumfer- ence, fairly exhibiting the natural ruga, villous membrane, and mucous coat, lining the gastric cavity. This appear- ance is almost invariably exhibited in the morning before rising from bed." Such was the very favourable subject on whom Dr. Beaumont's observations and experiments were made, and such were the numerous opportunities which he enjoyed for repeating them and verifying their accuracy. Having given this outline, we now return to the conside- ration of the gastric juice, on the origin and qualities of which it removes any uncertainty which previously existed. In treating of the properties of the gastric juice, I shall, on all disputed points, give a decided preferencfe to the ob- servations of Dr. Beaumont over those of any other physio- logist ; because, although a few cases have occurred in which, from external wounds, direct access has been given to the interior of the stomach, and Richerand and others have availed themselves of the opportunities thus afforded of adding to our knowledge of the digestive process, still, in most of them which have been recorded, the patients were a comparatively short time under observation, and were not sufficiently re-established in health to admit of either extensive or conclusive experiments being made. Whereas, in the case which Dr. Beaumont had the good fortune to meet with, the patient remained under his eye for several years, and in the enjoyment of the most robust health ; so that ample time and opportunity were afforded for every variety of experiments which reflection could sug- gest, and for their subsequent repetition under such modi- fications as seemed to be requisite for clearly distinguishing the accidental from the constant and essential result. In addition to these reasons, it_ ought to be added, in justice to the American physiologist, that, from the excellent judg- ment with which he carried on his investigations, and the scrupulous care with which he announces his results and separates facts from theory, it is impossible not to place great confidence both in his personal qualifications as an observer, and in the general accuracy of his statements. Moreover, as he enjoyed the rare advantage of seeing what 88 PECULIARITIES OF GASTRIC JUICE. he describes to have taken place in the stomach during healthy digestion, his evidence comes before us with the strongest possible,claims on our attention.* The first disputed point which is conclusively settled by Dr. Beaumont is, that the gastric juice does not continue to be secreted between the intervals of digestion, and does not accumulate to be ready for acting upon the next meal. By inducing St. Martin to fast for some hours, and then plac- ing him with the opening in the left side exposed to a strong light, so as to give a distinct view of the cavity of the sto- mach, Dr. Beaumont found its only contents to consist of a little viscid and occasionally slightly acidulated mucus mixed with saliva, and in no instance did he perceive any accumulation of the proper gastric juice. The same results had, indeed, been obtained by Tiedemann and other physio- logists before the publication of Dr. Beaumont's memoir ; but the evidence of the latter is so much more direct and incontrovertible, that it may justly be regarded as setting the question for ever at rest. Having proceeded so far, Dr. Beaumont next endeavour- ed to discover at what time the gastric juice begins to be poured out, and under what conditions its secretion is car- ried on ; and here again ocular inspection afforded him sa- tisfactory results * I cannot help thinking that, if St. Martin be still alive, which is \ most likely, some effort should be made either by the government or by a public subscription, to bring him over to this country, and, under the direction of a competent committee, subject him to such farther experiments as may be necessary to complete the investiga- tion. A similar opportunity may never again occur, and it would, therefore, be a disgrace to the science of the nineteenth century to allow it to pass unimproved. In a former edition I suggested that the Royal Society should take the necessary steps for this purpose ; but they, it appears, want funds. At the Newcastle Meeting of the British Association for the Promotion of Science, in 1838, a commit- tee recommended a grant of £200 from the general funds in aid of this object ; but at the suggestion, it is said, of the noble president, who considered such inquiries " disgusting," the recommendation was unfortunately negatived ! If my suggestion shall ever be acted upon, special care should be taken not to injure St. Martin's health by withdrawing him entirely from his accustomed diet and mode of life, otherwise the whole value of the experiment may be lost—the * object being to ascertain the laws and conditions of hkalthy diges- tion. In throwing out this suggestion, I need scarcely add, that I am far from undervaluing what Dr. Beaumont has accomplished, and that I consider it no disparagement to him to say, that he has left some subjects of interest connected with the inquiry still unde- termined. MODES OF OBTAINING GASTRIC JUICE. 89 It has already been remarked, that, on pushing back the valve which filled up the opening into the stomach, the cavity within became visible to a considerable extent; and that when St. Martin lay over for a time on the left side, a portion of the villous coat, large enough to exhibit several inches of its surface, generally protruded. Owing to these circumstances, Dr. Beaumont could easily observe what changes occurred, both when food was swallowed in the usual way, and when it was introduced at the opening left by the wound. Accordingly, on examining the surface of the villous coat with a magnifying glass, he perceived an immediate change of appearance ensue whenever any ali- ment was brought into contact with it. The action of the neighbouring bloodvessels was instantly increased, and their branches dilated so as to admit the red blood much more freely than before. The colour of the membrane con- sequently changed from a pale pink to a deeper red, the vermicular or worm-like motions of the stomach became excited, and innumerable minute lucid points and very fine nervous and vascular papillae could be seen arising from the villous coat, from which distilled a pure, colourless, and slightly viscid fluid, which collected in drops on the very point of the papilla? and trickled down the sides of the sto- mach till it mingled with the food. This afterward proved to be the secretion peculiar to that organ, or, in other words, the true gastric juice; the rnucous fluid secreted by the follicles, which some have mistaken for it, is not only more viscid, but wants altogether the acid character by which it is generally distinguished. Pursuing his experiments, Dr. Beaumont then found that the contact, not only of food, but of any mechanical irritant, such as the bulb of a thermometer, or other indigestible body, invariably gave rise to the exudation of the gastric fluid from these vascular papillae; but that in the latter cases the secretion always ceased in a short time, as soon apparently a-3 the organ could ascertain that the foreign body was one over which the gastric juice had no power. But the small quantity obtainable in this way is perhaps more pure and free from admixture, and, therefore, better adapted for examination, than any which can be produced under any other circumstances. Various methods have been employed for procuring the gastric fluid in a state of purity. Pieces of dry sponge, en- 8* 90 ELEMENTS OF GASTRIC JUICE. closed in a small hollow perforated ball with a string attach- ed to it, have been swallowed both by man and by inferior animals, and afterward withdrawn to have the juice express- ed from them. In some instances the stomachs of crimi- nals and animals killed after fasting have been opened, and the secretion collected. At other times the juice has been procured by voluntary or artificial vomiting. None of these methods is equal to that employed by Dr. Beaumont; but of the three the first is unquestionably the best, because, although no gastric juice previously exists, the very contact of the ball excites the secretion of a quantity sufficient to moisten the sponge. In the second mode of proceeding, any portion of juice secreted in consequence of a stimulus applied after the stomach is open, must necessarily be very small, and rendered impure by the large admixture of mucus which it will contain; while by the third method, as the gastric juice does not exist ready made in the stomach, either none but merely mucus will be procured, or it will be expelled mixed with the food or substance which had previously elicited its secretion. Gastric juice, in its purest form, and unmixed with any- thing except the small portion of mucus from which it can never be obtained entirely free, is described by Dr. Beau- mont to be a clear transparent fluid, without smell, slightly saltish, (probably from the admixture of mucus,) and very perceptibly acid. Its taste, he says, resembles that of thin mucilaginous water, slightly acidulated with muriatic acid. It is readily diffusible in water, wine, or spirits, and effer- vesces slightly with alkalis—a direct proof of its acid na- ture. It coagulates albumen, and is powerfully antiseptic, checking the progress of putrefaction in meat. When pure it will keep for many months, but when diluted with saliva it becomes fetid in a few days. According to Pro- fessor Dunglison, to whom some was submitted by Dr. Beaumont for analysis, it contains free muriatic and acetic acids—phosphates and muriates with bases of potassa, soda, magnesia, and lime—together with an animal matter solu- ble in cold but insoluble in hot water. Tiedemann and Gmelin, again, describe it as composed principally of mu- riatic and acetic acids, mucus, saliva, osmazome, muriate, and sulphate of soda, with little or no albumen ; and, ac- cording to Nthe same physiologists, the proportion of acid is always greatest when vegetables or other substances THE GASTRIC JUICE A SOLVENT OF FOOD. 9t of difficult digestion constitute the chief part of the diet. Other chemists give an analysis somewhat different from either of these ; a circumstance which was, indeed, to be expected, considering not only the differences caused by variations of diet and of health, but also the necessarily diffe- rent degrees of purity of the fluid submitted to examination. The most remarkable property of the gastric juice is unquestionably the power which it possesses of dissolving and reducing to the appearance of a soft thickish fluid mass everything in the shape of food which is submitted to its action—while it exerts no perceptible influence on living or inorganic matter; for, so far as is yet known, nothing which is not organized, or which is still alive, can serve as nutriment for the animal frame. Water is the only in- organic body which is taken into the system for its own sake, and all mineral and other inorganic productions enter it as component parts of previously organized substances of either an animal or a vegetable nature. To a great ex- tent, indeed, vegetation seems to be merely a process for the conversion of inorganic matter into a proper nutriment for the support of animal life ; and many species of animals seem in their turn to be little else than living machines for the conversion of vegetable substances into a nutriment fit for other species by which they are intended to be devoured It is true that, in some parts of South America, the natives, pressed by want, consume quantities of a soft unctuous clay, which is, of course, destitute of organization; but as there is every reason to believe that no nourishment is derived from it, and that it merely serves to allay the pang3 of hunger, such instances form no exception of the gene- ral rule. It would have been easy for the Creator to bestow such a structure on all animals, as to make them subsist entirely on vegetable aliment. But the arrangement which He has seen fit to adopt is the source of an infinitely greater amount of active enjoyment that what could otherwise have existed. Had there been no beasts of prey, the world would soon have been overrun with herbivorous creatures to such an extent, that their numbers would speedily have become excessive in reference to the possible supply of food, and there would have been infinitely more suffering from starvation and disease, than what actually arises out of their existing relation to each other. On the present 92 ACTION OF GASTRIC JUICE ON THE STOMACH. plan there is ample food and enjoyment for all; and when the time does arrive when one animal must become the prey of another, the deprivation of life is in most cases un- foreseen, and the suffering which attends it is in general only momentary in duration. There is thus both complete enjoyment of life while it lasts, and a great additional field opened for the support of an immense class of animals, which, with their present constitution, could not otherwise have existed at all.* The gastric juice, as already remarked, has no power over living animal matter—a most wise and admirable pro- vision, since otherwise it would at once have attacked and destroyed the very organ which produces it. This is the reason why certain worms are able to exist in the stomach of man and other animals ; and if it were possible for an oyster swallowed directly from the shell to continue to live, it would also effectually resist every attempt at digestion. But it, in common with most other beings, soon perishes in circumstances so foreign to its habits ; and when once dead, the gastric juice assumes the mastery, and speedily converts it into chyme. If anything could have opened Monte"gre's eyes to the fallacy under which he laboured in considering the gastric juice as almost identical with saliva, the circumstance we are now to mention would have sufficed. When a person, previously in good health, dies by a violent death, or when an animal is killed soon after a meal, it very often happens that, on opening the body after an interval of some hours, the stomach is found to be eroded, and its contents poured into the cavity of the abdomen, precisely as if a hole had been formed in it by ulceration. It was long before the reason of this was discovered ; but at length it was ascer- tained to arise from the action of gastric juice {the abun- dant secretion of which was provoked by the immediately preceding meal) upon the substance of the stomach, now subjected to its power from being deprived of life. This fact has been so often verified, that it is by all admitted as incontrovertibly true.f If, therefore, the gastric juice be * The reader will find the same line of argument most eloquently and successfully pursued by'Dr. Buckland in his admirable Bridge- water treatise on " Geology considered with reference to Natural Theology," which appeared subsequently to the first edition of thii volume. f Professor Carsewell, of the London University, has rendered an GASTRIC JUICE ANTISEPTIC. 93 merely saliva and mucus, we might expect to find after death distinct traces of similar results from the contact of saliva within the mouth or gullet; bufrtere no such erosion is ever witnessed, nor, as Montegre himself admits, does saliva exert any solvent power whatever over dead animal matter out of the body. These facts appear quite sufficient to convince any unprejudiced mind. The power of coagulating milk, and albumen or the white of eggs, is another remarkable property of the gas- tric jmce—and one so familiarly known, that in dairies an infusion of the stomach of the calf is in common use, under the name of runnet or rennet, for curdling milk. In infants, also, we know that the nurse's milk has scarcely reached the stomach before coagulation takes place; a fact which leads many experienced mothers to infer that the infant is already suffering from acidity, and to counteract the sup- posed evils by repeated doses of magnesia—which, of course, do more harm than good. The coagulation of milk in the stomach is so far from being a morbid process, that milk cannot be properly digested without it. By the separa- tion and absorption of the fluid whey, the curd is reduced to a proper consistence for being acted upon, both by the gastric juice itself and by the contractions of the muscular coat. The gastric juice is also powerfully antiseptic; that is to say, it prevents animal substances from becoming putrid, and even renders sweet such as have advanced a conside- rable way toward putrefaction. Dr. Beaumont mentions that the pure juice will keep unchanged for almost any length of time ; and, according to Spallanzani, meat may be preserved in it without taint for five or six weeks, or even longer. This antiseptic tendency of the gastric fluid ac- counts for the circumstance that little or no mischief results from the common practice among epicures, of not making use of game till the putrefactive process is advanced farther than is agreeable to the1 palates of the uninitiated. essential service to practical medicine, as well as morbid anatomy, t>y demonstrating, in an excellent paper published in the 34th vo- lume of the Edin. Med. and Surg. Journal, that softening and ero- sion of the stomach, considered by Broussais and others as always results of inflammatory irritation during life, are generally caused py the digestive action of the gastric juice after death. The essay is well worthy of an attentive perusal: but it would carry me too far to notice it here at greater length. 94 GASTRIC JUICE VARIES ACCORDING TO FOOD. The qualities of the gastric juice are so directly adapted to the natural food of the animal, that flesh introduced into the stomach of an ox or a sheep, for example, undergoes scarcely any change ; while vegetable food, on the other hand, remains equally undigested in that of a beast of prey. Thus, " when a hawk or an owl has swallowed a small bird, in the stomach of which have been seeds, these bodies are not dissolved by the gastric fluid,"* but pass through the intestines unaltered. Man, the dog, and some other crea- tures, possess the power of digesting all sorts of aliment, whether vegetable or animal, and are hence called omni- vorous or all-eating ; but even in them the relation which the properties of the gastric juice bear to the qualities of the food chiefly or exclusively used is so close, that, when a widely different kind is suddenly resorted to, indigestion is the almost inevitable consequence—because then the gastric juice has not had time to acquire its requisite adap- tation to the new materials on which it has to act. Hence also the danger arising from suddenly eating a full meal after having been long famished. The stomach, accustomed for a time to the smallest quantity, is no longer able to pro- vide gastric juice sufficient for the purposes of digestion ; and, being irritated by continued craving, its secretions are vitiated and its sensibility exalted to such a degree as to require the wisest management to enable it to regain its healthy tone. Trie gastric juice of carnivorous animals differs even in its chemical constitution from that of the herbivorous ; a circumstance which accounts for the difference observed in their action. In the former, such as that of birds of prey, serpents, and fishes, no free or uncombined acid can be detected, although it is invariably found in the gastric fluid of vegetable-eaters. In crows and dogs, on the other hand, and such animals as can live on either kind of aliment, it is never acid, except when they have been fed chiefly on grain or plants. In man the same relation has, by nume- rous experiments, been ascertained to exist. But although, in every class of living beings, the gastric juice is constituted with a direct relation to its natural food, still its qualities may be so much modified by a very gra- dual change of diet, as to fit it for digesting aliment of a * Macgillivray's Description of the Rapacious Birds of Great Bri- tlin, p. 24 GASTRIC JUICE VARIES ACCORDING TO FOOD. 95 very dissimilar or opposite kind. Thus, in the natural state, the stomach of a sheep exerts scarcely any action on beef or mutton ; but if the change from the one kind of food to the other be made by slow degrees, the gastric juice will in the end become so essentially altered as to enable it to digest both. In this way, as is mentioned by Delabere Blaine,* a horse at the Veterinary College was supported for some time by animal matter alone ; while others have subsisted on dried fish or on milk. It has been shown also, by John Hunter, Spallanzani, and others, that eagles, falcons, owls, pigeons, and domestic fowls may for a time be fed on aliments altogether foreign to their natural habits. But these facts only show the extent to which Nature will go, on an emergency, for the preservation of life ; and no more indicate the equal fitness of both kinds of aliment, than the fact of some men being able to stand for a few minutes on their heads proves an inverted position to be the natural attitude of the human race. In consequence of this adaptation of the gastric juice to the nature of the food, it is obvious that sudden and extreme changes from one kind of diet to another must be injurious, because the stomach has not time to modify its secretions sufficiently to meet the altered demand made upon its powers. This, accordingly, is one of the reasons why so much caution is used in bringing horses info condition after having been for some time in the pasture-field. When they have previously been on dry food in the straw-yard, corn may be given with greater safety: so that it is the change, not so much in quantity as in kind of aliment, which causes the risk. And on this account, when a horse is to be put upon hard food, after having been fed on grass or other succulent vegetables, Blaine recommends, not only that hay and corn should be given in very small quantity at first, but that the hay should be moistened and the corn mixed with bran and mashed; by which means having acquired a greater analogy to grass, it will be more easily acted upon by the gastric juice, which has been previously adapted for green food. Even in man the gastric juice undergoes considerable modifications, not merely according to the kind of aliment habitually used, but also according to the time of life, the wants of the system, the season of the year, and the state of * Blaine's Veterinary Art, 3d edit., p. 247. 96 GASTRIC JUICE VARIES ACCORDING TO FOOD. the health ; so that, while sudden and great changes from one kind of diet to another are positively hurtful on the one hand, absolute uniformity is not less objectionable on the other, because it leads to so great a uniformity in the quality of the gastric juice habitually secreted as to render it incapable of acting with due effect on any accidental variety of food, to which a change of circumstances may compel us. Many attempts have been made to ascertain to which of the elements of the gastric juice its power is chiefly to be ascribed, and experiments have been instituted on them individually to discover which of them is most nearly analo- gous to it in effect. 'From the general results, it appears that acetic acid (vinegar) and muriatic acid have a wider range of influence, and produce solvent effects more closely resembling those of gastric juice, than any other known substances. Both of these acids, it will be recollected, are constituent elements of the gastric fluid ; and it has, in consequence, been argued that to them it is indebted for all its energy. And, indeed, without laying too much stress on this real or supposed analogy, it is impossible to over- look the well-known fact, that scurvy and a highly alkaline state of the system are generally induced by a diet restrict- ed for a long time to animal food alone, and are prevented or cured most easily by a free use of lemon juice or of vegetable matter, either fresh or fermented. In these cir- cumstances the vegetable acid is probably efficacious, both by directly improving digestion and by combining with the excess of the alkaline salts already existing in the system. It is worthy of remark, too, that in weak stomachs acidity is almost invariably induced by the use of vegetable food, possibly to some extent for the very purpose of effecting its digestion ; for it has been ascertained beyond a doubt, that in herbivorous animals the gastric juice always con- tains some free or uncombtned acid—and in man also, after living much on vegetables for some time. The necessity of acid for the chymification of vegetable food affords an explanation of the fondness which the Ger- mans and Dutch display for saur-kraut—or cabbage in a state of acetous fermentation—and of its alleged easy di- gestibility. It explains also the general use of vinegar along with salads, cucumbers, oysters, salmon, and other substances of difficult digestion, and shows that its utility GASTRIC SECRETION VARIES FROM DISEASE. 97 is not imaginary, but loudly proclaimed by Nature's own acts. Another important principle, which Dr. Beaumont con- ceives to be established by his numerous experiments, and which forced itself upon him by degrees, is, that in health THE GASTRIC SECRETION ALWAYS BEARS A DIRECT RELA- TION TO THE QUANTITY OF ALIMENT NATURALLY REQUIRED by the system ; so that if more than this be taken, there will necessarily be too small a supply of the juice for the digestion of the whole. The principle here laid down is in perfect harmony with the sympathy which we have seen to exist between the stomach and the rest of the body, and, therefore, not only is highly probable in itself, but, if sound, will prove a most valuable guide in the practical regulation of diet. The number of phenomena which it explains, and its general applicability to daily use, afford no small pre- sumption of its truth. When, for example, we eat more than the wants of the system require, indigestion will fol- low, because there will be more food in the stomach than what the quantity of gastric juice provided is able to dis- solve ; the proportion of the juice secreted being in relation, not to what we eat, but to the actual wants of the system, which, in the case supposed, we have greatly exceeded. Here a remarkable harmony will be perceived between the quantity of the secretion and the true indications and uses of appetite as a guide to diet, explained in a preceding chapter, (p. 38.) The gastric secretion and the appearance of the villous coat undergo great modifications during disease, and on this subject also Dr. Beaumont's observations are highly valuable ; because, instead of merely inferring, as others are obliged to do, he enjoyed the privilege of seeing with his eyes what was actually going on. In the course of his at- tendance on St Martin he found that, whenever a feverish state was induced, whether from obstructed perspiration, from undue excitement by stimulating liquors, from over- loading the stomach, or from fear, anger, or other mental emotion depressing or disturbing the nervous system, the villous coat became sometimes red and dry, and at other times pale and moist, and lost altogether its smooth and healthy appearance. As a necessary consequence, the usual secre- tions became vitiated? impaired, or entirely suppressed ; and the follicles from which, in health, the mucus which pro- 9 98 GASTRIC JUICE DEFICIENT IN DISEASE. tects the tender surface of the villous coat is poured out, became flat and flaccid, and no longer yielded their usual bland secretion. The nervous and vascular papilla?, thus deprived of their defensive shield, were then subjected to undue irritation. When these diseased appearances were considerable, the system sympathized, and dryness of the mouth, thirst, quickened pulse, and other symptoms show- ed themselves ; and no gastric juice could be procured OR EXTRACTED EVEN ON THE APPLICATION OF THE USUAL STIMULUS OF FOOD. These facts, if correctly observed, are of extreme im- portance ; and, from the care with which Dr. Beaumont pursued his investigations, and their accordance with the facts recorded by preceding physiologists, I do not think their general accuracy can be called in question. The dry, irritated appearance of the villous coat, and the absence of the healthy gastric secretion in the febrile state, not only explain at once the want of appetite, nausea, and uneasi- ness generally felt in the region of the stomach, but show the folly of attempting to sustain strength, by forcing the patient to eat when food Cannot be digested, and when Nature instinctively refuses to receive it. Before dismissing this part of the subject, it may be re- marked, that the alleged sympathy of the stomach with the wants of the body has been denied, because the sense of hunger disappears the moment food is swallowed, or the stomach is distended even with clay or saw-dust, although the actual wants of the system cannot by possibility have been supplied in either case. But these facts seem to me rather to justify the inference that a sympathy does exist. Hunger ceases when food is taken, simply because now the 'condition of the stomach is in the desired relation to the state of the body, and the nerves consequently feel and transmit this impression td the more distant parts. In the other case, again, it ceases because the stomach cannot at first distinguish what is food from what is not ; and, there- fore, when distended, expresses content, because it feels satisfied that it has been honestly dealt with, and got what it wanted. But whenever it discovers the cheat, which it does in no long time, hunger returns, and can be properly appeased only by digestible substances. Dr. Beaumont, indeed, expressly mentions, that, although the gastric se- cretion commences the moment any indigestible body EXPLODED THEORIES OF DIGESTION. 99 touches the mucous surface of the stomach, it invariably ceases soon after discovering that the substance is one over which it has no power—thus strongly confirming the existence of the sympathy. Here it may be also proper to observe, that, from the frequent and pointed references which I have made to the results obtained by Dr. Beau- mont, some of my readers have imagined that I claimed for him the merit of the original discovery of all the truths which his experiments tend to establish. Nothing, however, was farther from my intention, and, accordingly, on page 84 I speak distinctly of his having eagerly em- braced the opportunity afforded him of " testing the pre- vailing doctrines " on digestion; and on page 88 and other places I state that the same results had previously been arrived at byTiedemann and other observers, but that the evidence in their favour adduced by Dr. Beaumont was "more direct and incontrovertible," and, therefore, more conclusive, than theirs—a position wholly at variance with any claim of discovery on his part. Indeed, the utter ab- sence of pretension in Dr. Beaumont's work is one of its most pleasing characteristics. CHAPTER V. THEORY AND LAWS OF DIGESTION. Different theories of Digestion—Concoction—Fermentation—Putre- faction—Trituration—Chemical solution—Conditions or laws of digestion—Influence of gastric juice—Experiments illustrative of its solvent power—Its mode of action on different kinds of aliment; beef, milk, eggs, soups, &c—Influence of temperature—Heat of about 100° essential to digestion—Gentle and continued agitation neeessary—Action of stomach in admitting food—Uses of its muscular motion—Gastric juice acts not only on the surface of the mass, but on every particle which it touches—Digestibility of different kinds of food—Table of results—Animal food most di- gestible-Farinaceous next—Vegetables and soups least digestible —Organs of digestion simple in proportion to concentration of nutriment—Digestibility depends on adaptation of food to gastric juice more' than an analogy of composition—Illustrations—No increase of temperature during digestion—Dr. Beaumont's sum- mary of inferences. Before entering upon the consideration of the theory of digestion which naturally evolves itself from the facts expounded in the preceding chapter, it may be of advantage to turn for a moment to the various theories which have prevailed since the subject first attracted the attention of the learned. 100 EXPLODED THEORIES OF DIGESTION. Hippocrates regarded digestion as a kind of concoction or stewing; and many of his followers believed that it is ef- fected in the stomach by the agency of heat alone, much in the same way as food is cooked over a fire. It is quite ascertained that heat favours the process, but it is pure absurdity to maintain that that agent alone will accomplish digestion. Others of the older physiologists contended that chymi- fication results from simple fermentation of the alimentary mass, and referred to the gas disengaged during difficult digestion as a proof that the process of fermentation goes on. But it is now demonstrated that the tendency of healthy digestion is rather to arrest than to induce fermenta- tion, and that the latter takes place only when disease exists, or when more food has been swallowed than the quantity of gastric juice secreted by the stomach is able to dissolve. Moreover, the products of digestion and of fermentation are so extremely different, that it is impossible to believe them to originate from the same chemical action. The next theory which prevailed considered digestion to be the result of the putrefactive process. The single fact, that the gastric juice not only arrests putrefaction, but even restores to sweetness meat in which that process is begun, is sufficient to demonstrate the wildness of such a supposition. Another set of physiologists imagined that trituration would account best for all the changes occurring in the food during digestion ; and, consequently, regarded the chyme as a sort of emulsion formed by the intimate mix- ture of the aliment with the juices of the stomach, just as an emulsion is formed by rubbing down almonds in a mor- tar. The advocates of this theory referred for proofs, not only to the contractile motions of the stomach already noticed, but to the muscular apparatus for trituration which forms so remarkable a feature in the gizzard of gra- nivorous birds. But, in adopting this conclusion, they forget that in birds the triturating apparatus does not di- gest, but serves, like the organs of mastication in man and quadrupeds, merely to bruise the grain on which the ani- mal lives. In birds, in fact, digestion begins only after the trituration is finished. A more recent and much more accurate view of diges- tion, is that which considers it as neither more nor less CONDITIONS REQUIRED FOR DIGESTION. 101 ■than a chemical solution of the food in the gastric juice. This theory is supported by a greater number of facts and experiments than any other; but, although substantially correct, it is perhaps too exclusive and limited in its princi- ples. It is true that, by the agency of gastric juice on food out of the body, a change very similar to chymifica- tion can be effected on it; but when we remember that chyme, or the result of real digestion, is essentially the same in its elementary or component principles, whatever be the kind of food from which it is formed—and that, as yet, we are acquainted with no purely chemical agent which, if applied to different substances, gives rise to the same uniform product—we shall be more willing to believe that chymification is neither a purely mechanical nor a purely chemical operation ; but the result of a vital pro- cess, to which both mechanical and chemical forces con- tribute, and which no action or combination of inanimate matter can either exactly imitate or supersede. To enable ourselves to appreciate correctly the nature of digestion, we must begin by considering the conditions essential for its performance, or without which it cannot be carried on. The first indispensable requisite is an adequate supply of gastric juice, and its thorough admixture with every par- ticle of the food on which it is to operate. The second is a steady temperature of about 98° or 100° Fahr ; and the third is the gentle and continued agitation of the alimen- tary mass in the stomach while digestion is going on. In illustration of the influence of the first condition, I may refer to the experiments already mentioned as having been made by Spailanzani, Stevens, and others, to show the solvent power of the gastric juice on food even out of the boay. Spailanzani states that, when small portions of well-masticated beef or mutton are placed in a vial with a due proportion of gastric juice, and the requisite tempera- ture and gentle agitation are secured by placing the vial in the arm-pit, the appearances presented at the end of a few hours are extremely analogous to those observed in the natural process of chymification; the meat being in both cases converted into the soft grayish mass of a pultaceous consistence called chyme. Dr. Beaumont, who was well aware of the importance of Spallanzani's researches, and of the almost universal 9* 102 AN ADEQUATE SUPPLY OF GASTRIC JUICE. adoption of his views by succeeding physiologists till con- fidence in their accuracy was for a time shaken by the bold and fallacious assertions of Montegre, felt that the opportunity afforded him by St. Martin's wound for verify- ing or disproving the experiments on which these views were founded, was much too valuable to be lost. He therefore entered upon a long series of investigations, of which the following is an imperfect, though I hope instruc- tive, abstract: To test the reality of the solvent powers ascribed to the gastric juice, Dr. Beaumont withdrew from St. Mar- tin's stomach about one ounce of it, obtained after a se- venteen hours' fast, by introducing first a thermometer to induce the secretion, and then a gum-elastic tube to carry it off. Into this quantity, placed in a vial, he introduced a piece of boiled recently-salted beef, weighing three drachms. He then corked the vial tightly, and immersed it in water raised to the temperature of 100°, which he had previously ascertained to be the heat of the stomach when the secre- tion was going on. In forty minutes digestion had dis- tinctly commenced on the surface of the beef. In fifty minutes the fluid became quite opaque and cloudy, and the texture of the beef began to loosen and separate. In sixty minutes chyme began to be formed. In one hour and a half the muscular fibres hung loose and unconnected, and floated about in shreds. In three hours they had diminished about one-half. In five hours only a few remained undis- solved. In seven hours the muscular texture was no longer apparent; and in nine hours the solution was completed. To compare the progress of digestion in the natural way with these results, Dr. Beaumont, at the time of com- mencing the experiment just described, suspended a piece of the same beef, of equal weight and size, within the stomach by means of a string. At the end of the first half hour it presented the same appearances as the piece in the vial ; but when Dr. Beaumont drew out the string at the end of an hour and a half, the beef had been com- pletely digested and disappeared, making a difference of result in point of time of nearly seven hours. In both the solution began on the surface, and agitation accelerated its progress, by removing the external coating of chyme as fast as it was formed. When the experiment was repeat- ed with chicken instead of beef, the solution was slower, ACTION ON GASTRIC JUICE. 103 from the greater compactness of the chicken not allqwing the gastric fluid to penetrate its substance so readily. Had the beef and chicken been masticated before being subjected to experiment, the difference between them in the rapidity of digestion would probably have been less. To ascertain still more accurately the difference be- tween natural and artificial digestion, (the one in and the other out of the stomach,) Dr. Beaumont put twelve drachms of recently-salted boiled beef into a vial, with the same number of drachms of fresh gastric juice obtained through the opening of the stomach after a fast' of eighteen hours ; and then placed the vial in a basin of water on a sand-bath, where he kept it at the heat of 100° Fahr., and continued to agitate it gently. Digestion soon com- menced and went on uniformly for about six hours, when it ceased. One-half of the meat was then dissolved, and the texture of the remainder loosened and tender—re- sembling the same kind of aliment when ejected from the stomach partly digested some hours after a meal, as fre- quently seen in cases of indigestion. On weighing the undissolved portion which remained after all action had ceased, six drachms and twelve grains of the beef were found to have been digested by twelve drachms* or nearly double its weight, of gastric juice. It thus appears that a given quantity of gastric fluid can digest only a relative proportion of meat ; so that, when more is eaten than what there is juice sufficient to dissolve, stomachic disor- der must necessarily follow. In this latter case Dr. Beau- mont found that the addition of fresh juice causes digestion to be resumed. To discover what influence would be exerted on food masticated, swallowed, and mixed with the gastric juice in the usual way, and then withdrawn from the stomach, Dr. Beaumont gave St. Martin an ordinary dinner of boiled salted beef, bread, potatoes, and turnips, with a gill of pure water for drink ; and twenty minutes afterward drew off through the opening about a gill of the contents of the stomach into an open-mouthed vial. In this short space of time digestion had already commenced, thus negativ- ing the common notion that an hour elapses before it be- gins. The vial was now placed in a water-bath, al a tem- perature of 100°, and continued there for five hours. Ex- amined at the end of that time, the whole contents were 104 MODE OF ACTION OF GASTRIC JUICE, found to be dissolved. On then extracting an equal quan- tity of chyme from the stomach, and comparing it with the solution in the vial, little difference was observable between them, except that the process had been some- what more rapid in than out of the stomach. But this expe- riment is remarkable in another point of view, as showing that in the short space of twenty minutes enough of gastric juice had been secreted for the entire completion of digestion. With a view to verify these results, and also to disco- ver the comparative digestibility of different kinds of ali- ment, Dr. Beaumont gave St. Martin for dinner eight ounces of recently-salted lean beef, four ounces of potatoes, some bread, and four ounces of boiled turnips. After fif- teen minutes he withdrew a portion of the contents of the stomach, and found that some of the meat had already been slightly digested. In a second portion, withdrawn at the end of forty-five minutes, fragments of the beef and bread were perceptible, and in a still more advanced state of digestion ; the meat was in small shreds, soft and pul- py, and the fluid containing it had become more opaque and gruel-like in appearance. When two hours had elapsed a third quantity was taken out, at which time near- ly all the meat had become chymified and changed into a reddish brown fluid ; but small pieces of vegetable matter now presented themselves for the first time, but in a state of digestion so much less advanced than the meat, that their peculiar structure was still distinctly visible. Some of the second and third portions, put into a vial and treat- ed in the usual way, advanced to complete digestion, as in the other experiment, except that the process was slower, and that a few vegetable fibres remained to the last undissolved ; thus confirming the general opinion that vegetables are more difficult of digestion than animal substances. The mode of solution by the gastric juice varies ac- cording to the nature of the food on which it acts. We have seen that it gradually reduces solids to a soft and fluid state ; but its effect on milk and albumen is diffe- rent. It begins by coagulating them, so as to give them the requisite consistence for being affected by the muscu- lar contractions of the stomach, and impregnated with the juice. Fifteen minutes after St. Martin had drunk half a pint of milk, a portion taken out of the stomach ACTION OF GASTRIC JUICE ON LIQUIDS. 105 by Dr. Beaumont presented the appearance of a fine loosely-coagulated substance, mixed with a semi-transpa- rent whey-coloured fluid. A drachm of warm gastric juice poured into two drachms of milk, at a temperature of 100°, produced a precisely similar appearance in twentv minutes. In another experiment, when four ounces of bread were given along with a pint of milk, and the con- tents were examined at the end of thirty minutes, the milk was coagulated, and the bread reduced to a soft pulp floating in a large proportion of fluid. In two hours the whole was digested. When the white or albumen of two eggs was swallowed on an empty stomach, small white flakes began to be seen in about ten or fifteen minutes, and the mixture soon as- sumed an opaque whitish appearance. In an hour and a half the whole had disappeared. Two drachms of albumen, mixed with two of gastric juice out of the stomach, under- went the same changes, but in a rather longer time. When the food is chiefly liquid, as when soup is taken f either alone or in large proportion, the more fluid part is speedily absorbed, to fit the remaining nutritious portion for being better acted on by the gastric juice and muscular power of the stomach ; but in impaired digestion the re- quisite absorption of the fluid part does not go on so rapidly. Fifty minutes after St. Martin had dined on vegetable soup, beef, and bread, Dr. Beaumont found the stomach to contain a pulpous mass, like thick gruel in consistence, and of a semi-gelatinous aspect. The fluid portion had been absorb- ed to such an extent, that the remainder was even thicker than is usual after eating more solid food. From many similar observations, Dr. Beaumont infers it to be a general law, that soups and liquids cannot be digested till they are formed into a thicker mass by the absorption of their watery part—as till then they are too liquid~to be easily acted on by the gastric juice. Hence their unfitness for weak sto- machs, and the impropriety of large libations of tea or coffee at breakfast by persons whose digestion is bad. During recovery from illness, chicken-tea, beef-tea, and soups are often useful, simply because the system then requires the liquid to make up its lost blood. Unfortunately Dr. Beaumont made few experiments on the action of gastric juice upon vegetables ; and, in the few recorded, he generally contents himself with noting the 106 INFLUENCE OF TEMPERATURE ON DIGESTION. length of time required for their solution, which generally proved considerably longer than for animal substances. , In one experiment, however, he states, that an hour after giving St. Martin nine ounces of raw, ripe, sour apples, the stomach was full of fluid and pulp, "quite acrid, and irritating the edges of the aperture, as is always the case when he cats acescent fruits or vegetables." In an hour and a half the contents were still more sharp and acrid, and the pulp of the apple visible. At the end of two hours the" stomach was empty, but the mucous membrane exhibited an irritated appearance. With farinaceous ve- getables, however, the results were different. Thus, when a pint of thick, rich, boiled sago, sweetened with sugar, was given, the whole was digested in less than two hours, and there was neither acrimony of the gastric contents nor smarting of the edges of the Wound ; on the contrary, it seemed peculiarly grateful to the stomach, and rendered the mucous membrane soft, uniform, and healthy. The same results followed a repetition of the experiment, and also when a pint of soft custard was taken. In some states of the stomach, it is true, even farinaceous food excites acrimony and irritation, but rarely in the same degree as the other forms of vegetable aliment. Such being the influence of gastric juice on different aliments at the natural heat of the body, we have now to ascertain, in the second place, what share the high temperature has in the result. To determine this point, Dr. Beaumont took out two ounces of gastric juice, and divided it into two equal por- tions, in separate vials. He added to each an equal weight of masticated fresh beef; and placed the one in a bath at the temperature of 99°, and the other in the open air at 34°. As a contrast to these, he placed beside the latter a third vial, containing the same weight of masticated meat in,an ounce of clear water. In two hours the meat in the warm vial was partially digested; that in the cold gastric juice was scarcely changed ; and the third portion, in the cold water, seemed only a little macerated. In six hours the meat in the warm vial was half digested, while that in the two others had undergone no farther alteration. The gastric juice in the first viaPhaving by this time dissolved as much as it could of the beef, four drachms more were added from the stc- INFLUENCE OF TEMPERATURE ON DIGESTION. 107 mach, and the vial was replaced in the bath. Digestion, which had previously ceased, was now resumed, and went on as steadily as if it had not been interrupted ; thus show- ing, in a striking manner, the impropriety of exceeding in our meals the quantity for which alone a sufficiency of gastric juice can be provided. At the end of twenty-four hours the three portions were examined. That contained in the warm juice was completely dissolved, and presented the usual appearances. The portions contained in the cold juice and in the cold water very much resembled each other, and exhibited no appearance whatever of chyme. They were macerated or softened, but not digested. These experiments, and others of a similar nature, show clearly that a temperature equal to ordinary blood-heat is requisite for chymification. To make sure that it was the low temperature alone which prevented the occurrence of digestion in the experi- ment detailed, Dr. Beaumont now placed the vial containing the meat which had been exposed without effect for twenty hours to the action of the cold gastric juice on a water- bath at the ordinary blood-heat. In a very short time " digestion commenced, and advanced regularly as in the other parcels." The same results were always obtained from a repetition of these experiments, so that they may be held as perfectly conclusive in establishing the essen- tiality of heat to the digestive process. Common obser- vation, indeed, establishes this truth. Dr. Kitchener, for example, after stating that " a certain degree of heat is absolutely necessary to excite and support a regular process of digestion," remarks that, "when the circulation is lan- guid and the food difficult of solution in aged persons and invalids, even external heat will considerably assist concoction, and the application of the calefacient concave (stomach warmer) will enable the digestive organs to over- come refractory materials, and convert them into laudable chyle."* Thirdly.—The necessity of gentle and continued agi- tation for the accomplishment of digestion is so obvious from the preceding exposition, that it requires no direct experiments to establish it. When portions of meat were suspended in the stomach, by a string so short as to pre- vent them from being fully subjected to the motion already » Art of Invigorating and Prolonging Life, 3d edition, p. 180. 108 INFLUENCE OF THE MUSCULAR CONTRACTION described as always going on during digestion, the action of the gastric juice was confined almost entirely to their surface, and a longer time was, consequently, required for their solution than when they were left at liberty. In like manner, when meat out of the stomach was placed in a vial containing gastric juice, its solution was uniformly accelerated by gentle agitation, which acted simply by removing the coating of chyme as it formed on the surface, and thus affording to the gastric fluid an easier access to the undigested portions below. Accordingly, when in one of Dr. Beaumont's experiments two ounces of unmasticated roasted beef were introduced through the external aperture into the stomach, and held by a string, only one-half of it was digested in four hours, evidently from the want of mastication confining the action of the gastric juice to the surface of the mass, and because the string prevented it from following the regular motions of the stomach. Having now made the reader sufficiently acquainted with the agents concerned in, and the conditions essential to, the performance of digestion out of the body, we have next to exhibit the same agents and the same conditions in their ordinary operation in the living being, and to describe the beautiful arrangements by which they are respectively and unerringly regulated. It has been already shown that, in endowing us with appetite, Nature has intended both to ensure by its means a timely provision for the wants of the system, and to guard against our eating more than enough to supply them. We have also seen that, within certain limits, the quantity of gastric juice secreted bears a direct relation to the quantity of food consumed ; that when the food exceeds considerably the real necessities of the system, a part of it remains undigested, because the stomach is unable to secrete a sufficiency of fluid for the solution of the whole, and that, as a necessary consequence, indigestion follows. This being the case, we may expect to find all the arrangements of Nature made with a view to prevent us from hastily filling the stomach to repletion, without being fully warned beforehand of the error we are committing. And such, accordingly, is the fact. Considered in this light, the processes of mastication, insalivation, and deglutition are not only useful in prepa- ring the morsel for the future action of the gastric juice, OF THE STOMACH ON DIGESTION. 109 but, by transmitting the food to the stomach in small portions at a time, likewise serve the important secondary purpose of preventing its too rapid or excessive distention. To this good end, indeed, the stomach itself contributes, as has been distinctly shown by Dr. Beaumont. In the natural state of that organ a regular and gentle contraction of its whole fibres and cavity follows the introduction of each individual morsel, and it is not till the relaxation consequent on that contraction takes place, that another is willingly admitted. This arrangement was more than suspected by other physiologists, but it remained for the American experimenter to demonstrate its existence and purposes. It is true that, during a hurried repast, for example, food may be rapidly introduced into the stomach by an active effort of the will, but it is precisely in such circumstances that we are apt to eat too much, and that indigestion follows ; because, from no time being allowed for the secretion of the requisite quantity of gastric juice, and its proper mixture with each portion of the aliment, the stomach is placed in an unnatural situation, and its nerves cannot receive the same impression of " enough eaten," which is designed by Nature to arise only from the one being duly proportioned to, and mixed with, the other. The advantage of the natural arrangement is, there- fore, confirmed rather than refuted by what may at first appear an exception. When Dr. Beaumont depressed the valve in St. Martin's stomach, and introduced a few spoonfuls of soup at the orifice, he observed the ruga? or folds of the mucous mem- brane to close gently upon it, gradually diffusing it through the gastric cavity, and completely preventing the entrance of a second quantity till this diffusion was effected—when relaxation again took place, and admitted of a farther supply. When solid food was introduced in the same way, either in larger pieces or finely divided, the same gentle contraction and grasping motion were excited, and continued from fifty to eighty seconds, so as to prevent more from being intro- duced without considerable force till the contraction was at an end. When St. Martin was so placed as to admit of the cardia or upper orifice of the stomach being brought into view, and was then made to swallow a morsel of food in the natural way, a similar contraction of the stomach, and closing of its fibres upon the bolus, was Invariably 110 ADMIXTURE OF FOOD AND GASTRIC JUICE. observed to take place; and, till this was over, a second morsel could not be received without a considerable effort. And accordingly, when, either from haste or hunger, we disregard the order of Nature, and hurriedly gulp down food without due mastication, and without allowing time for the regular contraction of the stomach, we necessarily ex- pose ourselves to the risk, both of overloading it and of ultimately impairing its digestive power. Such being the provision made for ensuring the gradual admission of food into the stomach, the next requisite is its proper admixture with the gastric juice. Food being the appropriate stimulus of the secreting ves- sels of the stomach, the moment the alimentary morsel comes into contact with the mucous membrane, the ac- tion of the latter, as was formerly pointed out, becomes in- creased ; its bloodvessels are distended, its colour deepens to a brighter red, and the gastric juice immediately begins to De poured out. The muscular fibres of the stomach, being acted upon by the same stimulus, next come into play, and execute their specific function of alternate contraction and relaxation. By these means the aliment speedily becomes impregnated with the gastric fluid, and undergoes the influ- ence of that continued gentle agitation already described as essential to digestion, and which seems to have for its chief object the careful admixture of every portion of the nutriment with the quantity of gastric juice necessary for its solution. The particles of food are thus continually changing place, and if the quantity taken be not to great for the power of the gastric juice which the stomach can supply, chymification goes on equally throughout; so that, if the contents of the stomach be withdrawn in from thirty minutes to an hour after a moderate meal, they will be found to consist of perfectly formed chyme and particles of food, intimately mixed and blended, in larger or smaller proportions, according to the vigorous or enfeebled state of the digestive organs, and the quality of the aliment it- self. So effectually, indeed, has the admixture of food and solvent juice taken place in this short time, that, as already shown, when a portion is removed from the stomach and placed in an appropriate vessel, digestion will commonly continue in it, provided it be placed in a proper temperature and subjected to gentle and continued agitation. It is the impossibility of its being adequately acted upon ADMIXTURE OF FOOD AND GASTRIC JUICE. Ill by the muscular contractions of the stomach which renders fluid and highly concentrated nourishment, when exclusively used, so difficult of digestion ; and hence the reason why a certain bulk and consistence given to whale oil, for example, by the admixture of such innutritious substances as vege- table fibre, bran, or even saw-dust, make it a more accep- table and digestible article of food to the inhabitants of the northern regions, than when it is consumed in its pure state. In like manner, in civilized society, bread, potatoes, and vegetables are useful, not less by giving the requisite bulk and consistence to the rest of the food, than by the nutri- ment which they contain. Soups, jellies, arrow-root, and similar substances are, for the same reason, more easily di- gested when eaten along with bread or some bulkier aliment, than when taken alone, especially if used for some time. The motion which we have seen to be excited in the stomach by the entrance of aliment is at first very gentle and slight; but in proportion as digestion proceeds or the organ is distended, it becomes more rapid and energetic; and then it serves the additional purpose of gradually pro- pelling the chyme through the pylorus into the intestine, there to be farther prepared and converted into chyle. The necessary churning or agitation of the food is, from the pecu- liar situation of the stomach, greatly assisted by the play of the diaphragm and abdominal muscles during inspiration and expiration ; and the diminution of the vivacity and ex- tent of the respiratory movement which always attends des- pondency and grief, is one source of the enfeebled digestion which notoriously accompanies or follows depression of mind. The same cause also leads necessarily to an unfa- vourable condition of the blood itself, which in its turn weakens digestion in common with every other function ; but the muscular or mechanical influence is that which at present chiefly concerns us. On the other hand, the active and energetic respiration attendant on cheerfulness and buoyance of spirits, adds to the power of digestion, both by aiding the motions of the stomach and by imparting to it a more richly constituted blood. If to these causes be add- ed the increase of nervous stimulus which pleasing emotions occasion in the stomach, (as in the muscles, and organs of secretion generally,) we shall have no difficulty in perceiv- ing why digestion goes on so well in parties where there is much jocularity and mirth. " Laughter," says Professor 112 GASTRIC JUICE ACTS ON EVERY PORTION Hufeiand, of Berlin, " is one of the greatest helps to diges- tion with which I am acquainted ; and the custom prevalent among our forefathers, of exciting it at table by jesters and buffoons, was founded on true medical principles. In a word, endeavour to have cheerful and merry companions at your meals : what nourishment one receives amid mirth and jollity will certainly produce good and light blood."* Exposed to the action of all the agents above enume- rated, and to the increased nervous and vascular excitement which are necessary during digestion, a singular change soon commences in the food, and goes on till chymification is completed. After a little while the contents of the stomach, whatever their nature and variety, begin to be converted into a substance of a homogeneous, soft, grayish, and viscid appearance, of a sweetish, fade, and slightly acid taste, but which still preserves some of the qualities of the food, and is called chyme. The chyme always forms on that part of the food with which the gastric juice is in im- mediate contact; and, in proportion as it is produced, it is carried gradually onward by the gentle motion of the sto- mach toward the pylorus, where, consequently, it always exists in the greatest quantity. At the cardiac or left end of the stomach it is most sparingly found, both because digestion is there only beginning, and because the chyme is speedily removed from it and carried away toward the py- lorus. The doctrine hitherto generally received, and held by Dr. Wilson Philip and others as demonstrated, is, that " the layer of food lying next to the surface of the stomach is first digested, and in proportion as this undergoes the pro- per change, and is moved by the muscular action of the stomach, that next in turn succeeds, to undergo the same change." Dr. Beaumont, however, declares that, what- ever may be the case in rabbits and other animals on which Dr. Philip's experiments were made, such was not the order observed in the stomach of Alexis St. Martin—and such, he naturally infers, is not the order in the human sto- mach in general. Nor is such, I may add, the order which either experience or a correct view of the antecedent cir- cumstances and physiological conditions ought to lead us to anticipate. When vomiting, for instance, occurs an hour » Art of Prolonging Human Life, English edition. London, 182a P. 282 OF FOOD WHICH IT TOUCHES. 113 or two after a meal composed of, different ingredients has been swallowed, no such separation into digested and un- digested portions is to be found, but the whole are observed to have undergone changes proportioned to their degrees of digestibility, whether they were eaten first or last. In conformity with this view, Dr. Beaumont mentions, that, when, St. Martin swallowed a mouthful of any tena- cious food after the digestion of the preceding meal was con- siderably advanced, he always saw it first pass toward the great curvature of the stomach, and then disappear. In a minute or two it reappeared, more or less broken down, and mixed with the general alimentary mass ; and in a short time longer it was so much changed as entirely,to lose its identity. From these and numerous other facts, Dr. Beau- mont infers, that " there is a perfect admixture of the whole ingestae during the period of alimentation and chymifica- tion ;" and that " the whole contents of the stomach, until chymification be nearly complete, exhibit a heterogeneous mass of solids and fluids—hard and soft, coarse and fine, crude andchymified—all intimately mixed, and circulating promiscuously through the gastric cavity, like the mixed contents of a close vessel, gently agitated or turned in the hand." (P. 112.) As we proceed we shall meet with various indirect proofs of these statements being correct. If Dr. Beaumont's observations on this subject are accu- rate, we may expect to find that chymification commences on the surface of each individual fragment of the food, and is not confined to the outer surface of the entire alimentary mass, as stated by Dr. Philip. Such, accordingly, is the fact. When Dr. Beaumont extracted a portion of the food through the opening half an hour or an hour after eating, he invariably found it composed of perfectly formed chyme and particles of food intimately mixed and blended ; and in these experiments every portion of the aliment was already so completely supplied with gastric juice, that its chymification proceeded till the whole was digested with no other aid than that of the requisite heat and agitation. When a meal is taken before the preceding one is out of the stomach, digestion is observed to be disturbed. Dr. Wilson Philip explains this by stating, that the newly swal- lowed food becomes imbedded in, and occupies the centre of, the older and half-digested mass, where it remains dis- tinct and untouched till the former meal is entirely disposed 10* 114 GASTRIC JUICE ACTS ON EVERY PORTION of. A more logical explanation, however, and one more in harmony with facts, is offered by Dr. Beaumont, who ascribes the disturbed digestion to the supply of gastric juice having been entirely taken up by the first meal, and to the stomach, now comparatively exhausted, being unable to secrete a fresh supply for the second—seeing that, in ordi- nary circumstances, its vessels secrete only enough to meet the real wants of the system. Dr. Beaumont adduces, in confirmation of this view, the fact that many children, and most cooks, are in the habit of eating small quantities of food almost evoryhour or two without their digestion suf- fering materially, because then the amount of gastric juice secreted is quite equal to the chymification of the whole quantity taken. Reasonable as this inference appears from the facts stated by Dr. Beaumont, I cannot help thinking that there is some- thing more in the constitution of the stomach than the mere deficiency of gastric juice, which renders the too early in- trusion of new food hurtful. We know, for example, that, at the commencement of digestion, the muscular contrac- tions of the stomach are comparatively slow and feeble, and that as chymification advances they become rapid and ener- getic, as if to remove the chyme as fast as it is formed. If, then, new food, for which the feebler movement is best adapted, be introduced when digestion is far advanced and the energetic motion going on, may not this disproportion be itself an impediment, and co-operate with the deficiency of the gastric juice in disordering digestion'? Moreover, as the stomach, in common with every other organ intend- ed for alternate activity and repose, is always more or lesa fatigued by the active fulfilment of its function, its prema- ture excitement by new food must add to its exhaustion and weaken its power, (in the same way in which fresh muscular exertion adds to the exhaustion of muscles already sufficiently exercised,) and, consequently, lead to imperfect digestion. Th% same principle which explains the necessity of re- pose for repairing the vascular and nervous energy of the stomach, when these have been excited and exhausted by the labour of digestion, also affords a solution of the ques- tion why the appetite does not return as soon as the sto- mach is empty, but begins to be felt only after the latter has enjoyed a period of repose, varying in duration with tha OF FOOD WHICH IT TOUCHES. 115 mode of life, the state of health, and the nature of the pre- vious meal. If we regard chymification as going on at the surface of every individual portion of the food, we at once see that the constant motion of the stomach serves, not only to affect the original mixture of the food with the gastric juice, but to remove the chyme from the surface of each little fragment of the alimentary mass in proportion as it is formed, and by this very removal to expose a fresh surface of the fragment to the contact of the mucous membrane, thereby enabling it to excite a farther secretion of the gas- tric juice, where, as sometimes happens, the stomach is unable to provide a sufficient quantity from the beginning. In this way the formation and removal of chyme go on from the very first, although, of course, more slowly than after the gastric solvent has had time to act. It is generally said that an hour elapses before any chyme is formed ; but Dr. Beaumont has detected its existence at a much earlier period, and is of opinion that, from the uniform and constant decrease in the contents of the stomach, which begins as soon as the food is swallowed, chymification commences almost immediately. This decrease, though slow at first, becomes gradually accelerated, till the whole mass is con- verted into chyme. Apparently in harmony with this more energetic action, the acidity of the gastric fluid also be- comes greater, and affords a greater stimulus, in proportion as digestion advances. As formerly explained, the thickish, semi-fluid, grayish chyme into which the aliment is converted, is gradually impelled toward the pyloric extremity of the stomach. On its arrival there the pylorus, or valve between the stomach and the intestine called the duodenum, opens and allows the chyme to pass into the intestine. But, by a curious mode of sensibility, if any portion of undigested food be mixed with it, the pylorus contracts upon it, refuses it egress, and throws it back into the stomach for farther digestion. If, however, anything really indigestible finds its way into the stomach, and presents itself at the pylorus—or if the stomach has temporarily lost its digestive power, and the food remains in it for many hours unchanged—then the pylorus, after repeatedly refusing egress, at last opens and allows it to pass into the gut. So marked is the contractile 116 COMPARATIVE DIGESTIBILITY OF impulse toward the pylorus when digestion is going on, that Dr. Beaumont found even the bulb of his thermometer carried down with a steady and considerable force. Such are the direct conditions requisite/or the fulfilment of digestion : but there remain others, of an indirect kind, which also require to be noticed. Of these, a due supply of arterial blood and nervous energy is the most remarka- ble; but as both produce their effect by modifying the secretions and motions of the stomach, already described as the direct requisites of digestion, it will save a good deal of repetition if, for the present, we take their influence for granted, and reserve their farther elucidation till we come to treat of the practical applications of the preceding expo- sition. Having thus obtained a comprehensive view of the agents employed in effecting digestion, and of the changes produced by it on different kinds of food, we find another important subject of investigation, immediately connected with the process, presenting itself—the comparative diges- tibility of different kinds of food. Dr. Beaumont did not neglect this branch of the inquiry ; but the experiments which he performed for its elucidation are, like those of most of his predecessors, deprived of great part of their value by the vague way in which they seem to have been conducted, and the common omission of all particulars in regard to those conditions which are known to exert a powerful influence on the progress of digestion. The following table, which I have arranged in a more lucid order than Dr. Beaumont has done, exhibits the ge- neral results of all the experiments made upon St. Martin posterior to 1825 ; and the average is deduced from thosa which were performed when the stomach was considered by Dr. Beaumont to be in its natural state, and St. Martin himself subjected to ordinary exercise. DIFFERENT KINDS OF FOOD. 117 TABLE showing the Mean Time of Digestion of the different Articles of Diet. Mode Time re- Articles of Diet. of quired for Preparation. Digestion. Rice - ... Boiled H. M. 1 Pig's feet, soused Boiled 1 Tripe, soused ... Boiled 1 Eggs, whipped ... Raw 1 30 Trout, Salmon, fresh Boiled 1 30 Trout, Salmon, fresh - Fried 1 30 Soup, barley ... Boiled 1 30 Apples, sweet and mellow Raw 1 30 Venison steak Broiled 1 35 Brains .... Boiled 1 45 Sago..... Boiled 1 45 Tapioca - Boiled 2 Barley - • Boiled 2 Milk .... Boiled 2 Liver, beef's, fresh - Broiled 2 Eggs, fresh ... Raw 2 Codfish, cured, dry ... Boiled 2 Apples, sour and mellow Raw 2 Cabbage, with vinegar Raw 2 Milk .... Raw 2 15 Eggs, fresh - Roasted 2 15 Turkey, wild - Roasted 2 18 Turkey, domestic - Boiled 2 25 Gelatine - - Boiled 2 30 Turkey, domestic - Roasted 2 30 Goose - - - Roasted 2 30 Pig, sucking • Roasted 2 30 Lamb, fresh ... Broiled 2 30 Hash, meat and vegetables Warmed 2 30 Beans, pod - Boiled 2 30 Cake, sponge Baked 2 30 Parsnips Boiled 2 30 Potatoes, Irish Roasted 2 30 Potatoes, Irish - Baked 2 30 Cabbage, head Raw 2 30 Spinal marrow - Boiled 2 40 Chicken, full grown Fricassee 2 45 Custard - Baked 2 45 Beef, with salt only Boiled 2 45 Apples, sour and hard • Raw 2 50 Oysters, fresh ... Raw 2 55 Eggs, fresh Soft boiled 3 Bass, striped, fresh . - - Broiled 3 Beef, fresh, lean, rare - Roasted 3 Beef steak - Broiled 3 Pork, recently salted - Raw 3 | Pork, recently "salted Stewed 3 118 COMPARATIVE DIGESTIBILITY OF TABLE showing Mean Time of Digestion—continued. Mode Time re- Articles of Diet. of quired for Preparation. Digestion. Mutton, fresh ... Broiled H. 3 M. Mutton, fresh ... Boiled 3 Soup, beans ... Boiled 3 Chicken soup ... Boiled 3 Aponeurosis ... Boiled 3 Cake, corn .... Baked 3 Dumpling, apple Oysters, fresh ... Boiled 3 Roasted 3 15 Pork steak ... Broiled 3 15 Pork, recently salted Broiled 3 15 Mutton, fresh Roasted 3 15 Bread, corn Baked 3 15 Carrot, orange - Boiled 3 15 Sausage, fresh Broiled 3 20 Flounder, fresh Fried 3 30 Catfish, fresh ... Fried 3 30 Oysters, fresh - • Stewed 3 30 Beef, fresh, dry ... Roasted 3 30 Beef, with mustard, &c. Boiled 3 30 Butter .... Melted 3 30 Cheese, old, strong Raw 3 30 Soup, mutton ... Boiled 3 30 Oyster soup ... Boiled 3 30 Bread, wheaten, fresh Baked 3 30 Turnips, flat ... Boiled 3 30 Potatoes, Irish ... Boiled 3 30 Eggs, fresh ... Hard boiled 3 30 Eggs, fresh .... Fried 3 30 Green corn and beans • • Boiled 3 45 Beet - Boiled 3 45 Salmon, salted - Boiled 4 Beef, fresh, lean Fried 4 Veal, fresh ... Broiled 4 Fowls, domestic ... Boiled 4 Fowls, domestic Roasted 4 Ducks, domestic ... Roasted 4 Soup, beef, vegetables, and bread Boiled 4 Heart, animal ... Fried 4 Beef, old, hard, salted - Boiled 4 15 Pork, recently salted - . Fried 4 15 Soup, marrow bones - Boiled 4 15 Cartilage - " - . . Boiled 4 15 Pork, recently salted - Boiled 4 30 Veal, fresh .... Fried 4 30 Ducks, wild ... Roasted 4 30 Suet, mutton Boiled 4 30 Cabbage, with vinegar - Boiled 4 30 Suet, beef, fresh ... Boiled 5 3 Pork, fat and lean Roasted 5 15 Tendon .... Boiled 5 30 DIFFERENT KINDS OF FOOD. s 119 This table is very interesting, but the results must nAt be too much relied upon, or regarded as representing the uniform rate of digestibility. We have already seen that chymification is greatly influenced by the interval which has elapsed since the preceding meal, the amount of ex- ercise taken, the keenness of the appetite, the state of the health and mind, the completeness of the mastication, the state of rest or exercise after eating, and various other cir- cumstances ; and, above all, the quantity swallowed, in pro- portion to the gastric juice secreted. And, consequently, if an experiment be made without regard to these conditions, and without anything being recorded, except the time oc- cupied in digestion in the individual case, the conclusions deduced from it may be most fallacious. The very aliment which, taken in full quantity, remains on the stomach for hours, may, in a smaller quantity, be entirely digested in one-third of the time. Thus, in the foregoing table, two and a half hours are set down as the average period re- quired for the chymification of jelly ; and yet, in one of Dr. Beaumont's experiments, we find that eight ounces of that substance were entirely digested in one hour. So that, if all the other conditions are not carefully kept in view at each trial, the results cannot possibly be held as conclu- sive. It may be said that, on the occasion just alluded to, St. Martin's digestion must have been particularly good—and, in truth, it seems to have been so; for at nine o'clock, a. m., he breakfasted on soused tripe, pig's feet, bread and coffee, and yet one hour later no vestige of any of these savoury things remained in the stomach. What renders this result the more remarkable, is the fact, that, in an- other table, a simple breakfast of coffee and bread is set down as having required four hours for its digestion. The rapid disposal of the same elements with the addition of soused tripe and pig's feet, instead of disproving my position, evidently strengthens it, by showing that, if from any cause the digesting power varies in intensity, the re- sult obtained from the experiment on one kind of food cannot, with any show of reason, be considered as an ac- curate index of its rate of digestibility in comparison with that of other kinds. This neglect of the other conditions is accordingly the circumstance which throws a doubt over the results, not 120 COMPARATIVE DIGESTIBILITY OF only of Dr. Beaumont's experiments, but of those of every other inquirer. Dr. Beaumont, indeed, candidly admits, that his were performed for the purpose of demonstrating other important principles connected with digestion, and not at all with the view of determining the comparative rates of digestibility of different kinds of aliment; and, in alluding to the various requisites for a satisfactory series of experiments, he himself justly states, that this would be a Herculean task which it would take years to accom- plish. In considering the following general results, then, the reader ought to bear in mind that they are only pro- bable and approximative, and not strictly demonstrated or certain. As a general rule, animal food is more easily and speedi- ly digested, contains a greater quantity of nutriment in a given bulk, and, therefore, satisfies hunger for a longer time than either herbaceous or farinaceous food; but, apparently from the same cause, it is also more heating and stimulating. Minuteness of division and tenderness of fibre are shown by Dr. Beaumont's experiments to be two grand essentials for the easy digestion of butcher- meat ; and the different kinds of fish, flesh, fowl, and game are found to vary in digestibility chiefly in proportion as they approach or depart from these two standard qualities. Farinaceous food, such as rice, sago, arrow-root or gruel, is also rapidly assimilated, and proves less stimu- lating to the system than concentrated animal food ; but as it affords no scope for the due action of the muscular coat of the stomach, its exclusive use for any length of time seldom fails to weaken that organ and impair diges- tion. For the same reason, however, it becomes a very appropriate aliment, where stomachic irritation already exists. When the stomach is in a healthy state, milk is digested almost as easily as farinaceous food, and is equally unstimulating. The other kinds of vegetable substance are the slowest of all in undergoing digestion, and very frequently pass out of the stomach and through the bowels comparatively little changed ; and hence the uneasiness which their presence so often excites in the intestinal canal, especially in persons of weak digestion, owing to the nerves of the intestines having a relation to chyme or digested food, and not to substances which resist the action of the gastric DIGESTIBILITY OF DIFFERENT KINDS OF FOOD. 121 juice. In a given bulk they contain less nutriment, and excite the system less, than any other kind of food ; so that they are well adapted for the diet of those in whom it is necessary to avoid every kind of stimulus, and who are not subjected to great muscular exertion ; but to a per- son undergoing hard labour they afford inadequate support. Liquids—soup, for example—do not call into play the muscular coat of the stomach, and are so slow of digestion where that organ is already weakened, that they often give rise to acidity ; and hence they are unfit for most dyspep- tic patients. Before the gastric juice can act upon them, the fluid part must be absorbed and the mass thickened to a proper consistence for undergoing the usual churning motion. On examining the contents of the stomach an hour after St. Martin had dined on beef soup, Dr. Beau- mont found that on one occasion the absorption of the watery part had been carried so far as to leave the remain- der of even a thicker consistence than after an ordinary solid meal, but a similar result follows only when the diges- tive powers are very vigorous. When drink'is swallowed, it also is carried off by absorption, and is not digested or allowed to pass through the pylorus. One purpose of this provision seems to be to prevent the gastric juice from being rendered inefficient by too much dilution. When the food on which an animal lives is of a highly concentrated kind, and contains much nourishment in a small bulk, the apparatus of organs provided for its diges- tion is on a correspondingly small scale in point of extent. Thus, in carnivorous animals, whose food is, bulk for bulk, the most nutritions of all, the stomach and intestines are simple and short, the latter not exceeding in length more than from one to four or five times that of the body. In herbivorous animals, on the other hand, whose food is sparingly nutritious, and, therefore, requires to have a large bulk or volume, the stomach, as we saw in a former chap- ter, is greatly more complicated, and the length of the intestines enormously increased. Man, being intended to feed on both animal and vegetable substances, possesses an organization which holds an intermediate place between the two extremes. In him neither are the intestines so short as in carnivorous animals, nor have they the com- plexity and length characteristic of the herbivorous—thus rlearly showing the intentions of Nature in regard to his II 122 WHY ANIMAL FOOD IS MORE DIGESTIBLE food, and at the same time allowing him a considerable latitude of adaptation when the force of circumstances for a time denies turn access to any variety. Animal food being in general more quickly digested than vegetable, and a simpler organization being sufficient for its conversion into chyme, many physiologists have inferred that this is owing solely to its being already of an animal nature, and, therefore, requiring scarcely any change to fit it for becoming a constituent part of the living fibre. But I agree with Dr. Beaumont in thinking that this explanation is more gratuitous than philosophical, and that the process of chymification implies almost as complete a change in the one instance as in the other. In both the operation of the gastric juice seems to be en- tirely analogous. In both a complete solution takes place, and the chyle'into which animal food is ultimately convert- ed, bears no greater resemblance to the future animal fibre than does that produced from vegetable aliment. Thus the chyle of a horse, which lives exclusively on vegetables, has quite as great a resemblance to its future muscle, as that of a tiger, a lion, or a fox has to its future produce. Besides, whether the food be animal or vegetable, the ul- timate result of digestion is always the formation of new animal matter; but in the former case the nutritive par- ticles are mixed up with a smaller proportion of innutri- tious matter than in the latter, and, consequently, a larger quantity of them can be extracted from a given bulk in a shorter time, than in the case of vegetables. There are, most probably, also minute differences in the chemical composition of the chyle derived from different kinds of food ; but its general nature—its fitness for forming new animal tissue—and that of the process by which it is pro- duced, are always the same. Animal food, it is true, affords a more stimulating nutri- ment than farinaceous and other kinds of vegetable aliment, and hence it is avoided in diseases of excitement. But it seems to me that this stimulus is owing, not only to its own inherent properties,,but also to its more highly concentrated state, and to the much greater quantity of chyle which is derived from it than from an equal bulk of vegetable ali- ment. From the numerous experiments of injecting water, poisons, and other substances into the veins, performed by Magendie and others, we have direct proofs that the sain* THAN VEGETABLE. 123 agent which, introduced rapidly into the system, will some- times act so powerfully as to destroy life, will excite scarce- ly any perceptible disorder if introduced very slowly. Ana- logy, therefore, bears us out in believing that the rapid. admixture of very nutritious chyle with the blood may over- stimulate the system, when its more gradual introduction would have produced no such effect. At the same time, there can be no doubt that there is also a greater inherent stimulus in animal than in vegetable aliment. It seems to be partly for the purpose of obviating the evil of the too rapid introduction of nutriment, and partly for that of varying the stimulus, that Nature has rendered a certain bulk of food advantageous to digestion, and decreed that no animal can long retain its health if fed on highly concentrated aliment alone. Dogs fed on oil or sugar, which are almost wholly converted into chyle, become dis- eased and die in a few weeks ; and, as Dr. Paris has acutely remarked, the very capacity of our digestive organs is a proof that Nature never intended them for the exclusive recep- tion of highly concentrated food. Dr. Paris refers to post- horses fed chiefly on beans and corn, as instances among the lower animals of the insalubrity of too condensed nutriment, and shows that they live constantly on the brink of active dis- ease, and every now and then require bleeding, laxatives, and emollients, to keep them in condition. Sportsmen, boxers, and others, who train themselves for severe exertion, are ad- ditional examples showing that a similar mode of living in- duces a morbid tension of the system which cannot be long kept up without danger. The Kamtschatdales sometimes live with impunity for months on fish-oil, by wisely mixing it up with saw-dust or other indigestible vegetable fibre, which has the double advantage of diluting the food and of afford- ing due scope for the action of the muscular coat, and thus placing the food in more perfect harmony with the constitu- tion of he stomach. If the preceding explanation of the more rapid digestion of animal than of vegetable substances, and the higher sti- mulus which they afford, be correct, the common notion of the former being more digestible than the latter, solely be- cause there is a greater.analogy between animal food and the system which it goes to nourish, and, therefore, a smaller change to be undergone, necessarily falls to the ground. If it be true—which it seems to be—that, in the natural 124 DIGESTIBILITY OF FOOD EXPLAINED. state, in a temperate climate, animal food is more easily digested than vegetable, the fair inference ought rather to be that the system requires the former in larger proportion than the latter, and that the gastric juice is purposely con- stituted with reference to this circumstance. Accordingly, in the Arctic Regions, where the climate renders great sti- mulus necessary, animal food, of to us the most indigesti- ble kind—that consisting of pure fat and oil—is eaten in immense quantities and digested with enviable facility ; while in India and other tropical climates, where much less stimulus is required, the natives digest vegetable aliment with at least equal ease and satisfaction. If, as Dr. Paris imagines, animal food owes its digestibi- lity simply to its possessing " a composition analogous to that of the structure which it is designed to supply," and, therefore, requiring " little more than division and depura- tion," instead of the alleged " complicated series of decom- positions and recompositions which must be effected before vegetable matter can be animalized of assimilated to the body,"*—it follows that butcher-meat must in all climates and situations be more digestible than vegetables; and that raw meat, which has the greatest analogy of all to the struc- ture of the body, must require still less digestive power for its solution and assimilation than cooked meat. These propositions, however, are wholly at variance with experi- ence : in particular, the effect of cooking is unquestionably to induce a change of composition subversive of the analogy on which Dr. Paris rests his opinion. That the easier digestibility of animal food in man arises chiefly from its greater adaptation to the qualities of the gastric juice, and not from any such analogy as that now alluded to, is rendered still more probable by the fact, that in him the gastric fluid contains scarcely any free acid, ex- cept where the diet has consisted for some time principally of vegetables; whereas it always contains a considerable proportion of acid in herbivorous creatures. In the latter, moreover, the analogy is quite as great between animal sub- stances and their own structure as in man, and yet to a cow beef is much more indigestible than grass, notwithstanding the " decompositions and recompositions " which the latter is supposed to require before becoming animalized. Dr. Beaumont is, therefore, quite justified in maintaining, that ♦ Paris on Diet, p. 93. HEAT OF STOMACH DURING DIGESTION. 1251 the process of digestion implies as complete a solution and recomposition in the case of animal as of vegetable sub- stances ; and that the rapidity with which the chyrhification of either is effected depends more on' its adaptation to the properties of the gastric juice provided by Nature for its solution, than on the closeness of resemblance oj its own composition to that of the body of which it is to become a part. Another prevalent notion—that the digestive apparatus is simpler and shorter in carnivorous than in herbivorous animals, merely because their food is more analogous in composition to their own bodies, and therefore requires less perfect digestion—seems to me equally unfounded, and to be negatived by the fact that, in the grain-eating birds, in the constituent elements of whose food there is no such analogy, the intestines, nevertheless, scarcely exceed in length those of carnivorous birds—a circumstance at va- riance with the notion of length being necessary solely on account of the great elaboration required for the conversion of vegetable into animal substance. The true principle—■ and it is important to notice it, as the error is generally adopted—appears to be, that where the food of the animal contains much nutriment in a small bulk, there the stomach and intestinal canal are simple and short; but where, on the contrary, it contains little nutriment in a large bulk, there great capacity, complexity, and length become re- quisite to enable the animal to elaborate a sufficiency of; nourishment for its subsistence, by taking in the requisite quantity from which it is to be derived. Accordingly, in the elephant and some other herbivorous animals we find the capacity to depend, not on the length, but on the width and increased surface of the intestine, or, in other words, on the greater calibre of its cavity ; whereas, in some fishes which live on very concentrated aliment, the intestinal canal is not much more than the length of the body—thus showing that the common opinion on the subject is utterly untenable: Before concluding his experiments on the agents em- ployed in digestion, Dr. Beaumont made many observations with a view to ascertain whether any increase of tempera- ture occurs during that process. By introducing a ther- mometer with a long stem at the external opening into St. Martin's stomach, both before and during chymification^he succeeded in obtaining very accurate information on this 11* 126 dr. beaumont's general inferences. point. In two or three of the experiments the heat of the stomach seemed to be increased after taking food, but in by far the greater number the temperature remained the same. It appears, however, that the variations of the at- mosphere produce a sensible change on-the heat of the stomach—a dry air increasing and a moist air diminishing it. The ordinary temperature may be estimated at 100° Fahr., and in several instances it was higher at the pyloric than at the cardiac end. On one cloudy, damp, and rainy day the thermometer rose only to 94°, and on another to 96° ; whereas next day, when the weather was clear and dry, it rose to 99°, and on that following, when the weather was both clear and cold, to 100°. On several occasions it rose as high as 102°, and once to 103° ; but these were after exercise, which was always observed to cause an in- crease of two'or three degrees. We have already seen that artificial digestion is entirely arrested by cold, and is re- sumed on raising the temperature to ordinary blood-heat. Such, then, are the phenomena and conditions of healthy digestion, and such is the light thrown upon them both by the valuable publication of the American physiologist. Before leaving this branch of the subject, however, it may be useful to lay before the reader, as a kind of summary, the principal inferences deduced by Dr. Beaumont from his numerous experiments and observations. But in doing so I shall attempt to arrange the results in their natural order; for in the original work they are given without reference either to logical sequence or to time. INFERENCES FROM DR. BEAUMONT'S EXPERIMENTS AND OBSERVATIONS.* 1. That hunger is the effect of distention of the vessels that secrete the gastric juice. 2. That the processes of mastication, insalivation, and deglutition, in an abstract point of view, do not in any way affect the digestion of the food ; or, in * The inferences are given in Dr. Beaumont's own words, and the italics also are his. It is needless to say that Dr. Beaumont does not present these inferences as discoveries. Most of them were known before ; but he has the merit of adding greatly to the strength of the evidence on which they rest, and of substituting certainty for doubt in many instances. The very title of " Inferences " which he modestly gives them, implies that he does not even consider them as proved, and still less as discoveries ; although a learned review erof the first edition charges him with this presumption. BR. BEAUMONT^S GENERAL INFERENCES. 127 other words, when food is introduced directly into the stomach in a finely divided state, without these previous steps, it is as readily and as perfectly di- gested as when they have been taken. 3. That saliva does not possess the properties of an ali- mentary solvent. 4. That the agent of chymification is the gastric juice. 5. That the pure gastric juice is fluid, clear and transpa- rent ; without odour ; a little salt; and perceptibly acid. !6. That it contains free muriatic acid, and some other active chemical principles. 7. That it is never found free in the gastric cavity ; but is always excited to discharge itself by the intro- duction of food or other irritants. 8. That it is secreted from vessels distinct from the mu- cous follicles. i 9. That it is seldom obtained pure, but is generally mixed with mucus, and sometimes with saliva. When pure it is capable of being kept for months, and per- haps for years. i. 3. That it coagulates albumen, and afterward dissolves the coagula. 11. That it checks the progress of putrefaction. 12. That it acts as a solvent of food, and alters its pro- perties. 13. That, like other chemical agents, it commences its ac- tion on food as soon a3 it comes in contact with it. 14, That it is capable of combining with a certain and fixed quantityof food, and when more aliment is present- ed for its action than it will dissolve, disturbance of the stomach, or " indigestion," will ensue. 15 That its action is facilitated by the warmth and motions of the stomach. 16 That it becomes intimately mixed and blended with the ingestae in the stomach by the motions of that organ. 17. That it is invariably the same substance, modified oniy by admixture with other fluids. •18. That the motions of the stomach produce a constant churning of its contents, and admixture of food and gastric juice. 19. That these motions are in two directions, transversely and longitudinally. 128 dr. Beaumont's- general inferences. 20. That no other fluid produces the same effect on foorj that gastric juice does; and that it is the only sol- vent of aliment. 21. That the action of the stomach and its fluids is the same on all kinds of diet. 22. That solid food, of a certain texture, is easier of di gestion than fluid. 23. That animal and farinaceous aliments are more easy of digestion than vegetable. 24. That the susceptibility of digestion does not, however, depend altogether upon natural or chemical distinc tions. 25. That digestion is-facilitated by minuteness of division and tenderness of fibre; and retarded by opposite qualities. 26. That the ultimate principles of aliment are always the same, from whatever food they may be obtained. 27. That chyme is homogeneous, but variable in its colour and consistence. 28. That, toward the latter stages of chymification, it be- comes more acid and stimulating, and' passes more- rapidly from the stomach. 29. That the inner coat of the stomach is of a pale pink colour, varying in its hues according to its full or empty state. 30. That, in health, it is sheathed with mucus. 31. That the appearance of the interior of the stomach, in disease, is essentially different from that of its healthy state. 32". That stimulating condiments are injurious to the healthy stomach. 33. That the use of ardent spirits always produces disease of the stomach if persevered in. 34. That water, ardent Spirits, and most other fluids, are not affected by the gastric juice, but pass from the stomach soon after they have been received. 35. That the quantity of food generally taken is more than the wants of the system require ; and that such ex- cess, if persevered in, generally produces, not only functional aberration, but disease of the coats of the stomach. 36. That bulk as well as nutriment is necessary to the- articles of diet. NATURE of CHYLIFICATION. lira 37. That bile is not ordinarily found in the stomach, and is not commonly necessary for the digestion of the food ; but, 38. That when oily food has been used it assists its digestion. 39. That oily food is difficult of digestion, though it con- tains a large proportion of the nutrient principles. 40. That the digestibility of aliment does not depend upon the quantity of nutrient principles that it contains. 41. That the natural temperature of the stomach is about 100° Fahrenheit. 42. That the temperature is not elevated by the ingestion of food. 43. That exercise elevates the temperature ; and that sleep or rest, in a recumbent position, depresses it. 44. That gentle exercise facilitates the digestion of food. 45. That the time required for that purpose is various, de- pending upon the quantity and quality of the food, state of the stomach, &c.; but that the time ordi- narily required for the disposal of a moderate meal of the fibrous parts of meat, with bread, &c, is from three to three and a half hours. A few more inferences are given, trht are here omitted because they refer exclusively to the chyle, which has not yet been treated of. The first is probably erroneous, and the second and seventeenth are, perhaps, too strongly ex- pressed. A complete change of diet, for example, causes some variation in the gastric juice, although the latter in- ference, taken in a literal sense, affirms the contrary. CHAPTER VI. CHYLIFICATION, AND THE ORGANS CONCERNED IN IT. Chyliflcation—Not well known—Organs concerned in it—The intestinal canal—Its general structure—Peritoneal coat—Mesen- tery—Muscular coat—Uses of these—Air in intestines—Uses of —Mucous coat—Analogous to skin—The seat of excretion and absorption—Mucous glands—Absorbent vessels—Course of chyle toward the heart—Nerves of mucous coat—Action of bowels ex- plained—Individual structure of intestines—The duodenum; jeju- num ; and ileum—Liver and pancreas concerned in chyliflcation —Their situation and uses—Bile, its origin and uses—The pan- creas—Its juice—The jejunum described—The ileum ; ccecum ; colon ; and rectum—Peristaltic motion of bowels—Aids to it— Digestion of vegetables begins in stomach, but often finished in the bowels—Illustration from the horse—Confirmation by Dupuytren. The conversion of food into chyme, an operation which, 2.6 we have seen, takes place in the stomach, is only one K39 NATURE OF CHYLIFICATION. •f the series of changes which aliment undergoes before- becoming fit to be assimilated with the living body ; and the next process which we have to notice is chyliflcation, er that by which, chyme is converted into chyle. In proportion as chyme is formed from the food, it is. gradually propelled, as already shown, through the pyloric orifice of the stomach into the duodenum or beginning of the small intestine. On its arrival there it is acted upon by the bile from the liver and the pancreatic juice from the pancreas; and the result is the separation of the chyme into two distinct substances—the one a milky-white fluid called chyle, which is absorbed into the system, and forms nutriment; and the other a yellowish and more consistent mass, which is the indigestible remains of the food, and which, after traversing the whole length of the intestinal canal, and being there mixed with the waste matter sepa- rated from,the blood in order to-be thrown out of the system through the same channel, is at last expelled in the form of faces or excrement. If physiologists experience much difficulty in satisfactorily explaining all the phenomena of chymification or stomach digestion, the reflecting reader will not be surprised to learn that they are still more puzzled to account for those of ehylification or intestinal digestion. The organs concerned in the latter are so deep-seated and inaccessible during life, that very few opportunities occur of obtaining accurate information on the subject; and, therefore, in what follows, I shall not enter into disputed or intricate details, but con- fine myself to such general views as are not contested, and as the reader may easily understand. Fortunately, igno- rance of this branch of the inquiry is of less practical inv portance than if it extended to stomachic digestion also ; because such is the harmony between all the parts-of the system, that whatever conduces to the perfect accomplish- ment of the first stage of the process, chymification, is in so far equally conducive to the proper fulfilment of ehylifica- tion or intestinal digestion. The simple fact, indeed, of our having no direct control over the process of ehylification, and of our being able to modify it only by varying, through the medium of the sto- mach, the elements out of which chyle is to be formed and the mode in which they shall be digested, is a proof that, practically speaking, it is chiefly the laws or conditions of INTEST1NAT. CANAT.. 131 stomachic digestion which are intended to regulate our con- duct ; and that, in obeying them, we in reality obey also those of intestinal digestion. The organs concerned in ehylification are the duodenum, the liver, and the pancreas ; but, in order to avoid repetition, I shall, in describing the first, notice also the remainder of the intestine. The intestine or intestinal canal, as represented in the subjoined figure, begins at the pyloric orifice of the stomach P, and after many windings and turnings, called convolutions, ■(from the Latin word convolutus, rolled or folded together,) terminates in the rectum or straight gut Y, at the external orifice, called the anus. Although continuous throughout its whole extent, the intestinal tube is, nevertheless, divided by anatomists into six portions, to each of which a different name is assigned : the distinction between some of these is more nominal than reaj, but it still continues to be made on account of its convenience. The first grand division is into the small and great intes- tines ; the former beginning at the stomach, including all the convolutions marked R S S S S—and the latter begin- ning at T, where the small intestine terminates, and inclu- ding the large gut U TJ U U X Y Y, which surrounds, and is partly hidden by, the other bowels. The small intestines, again, are subdivided into three portions—the duodenum, the jejunum, and the ileum ; and the larger, in like manner, into three portions—the caput ccecum or simply the caecum, the colon, and the rectum. Of the whole length, the small intestines constitute by much the greater part, and they differ somewhat from the larger in function as well as in magnitude. In structure, the intestines exhibit a great analogy with the stomach. They consist, in common with it, of three coats or layers of membrane ; the outer or peritoneal—the middle or muscular—and the internal, mucous, or villous. The peritoneal coat is the white, firm, smooth, shining, and moist membrane, seen on the outside of the intestine on opening the cavity of the abdomen. It serves both as a support and as a medium of attachment to fix the intes- tine in its place. By its smooth, soft, and lubricated sur- face, it admits readily of the change of place among the bow- els necessarily produced by respiration, exercise, and even by different degrees of distention of the bowels themselves. INTESTINE--THE MESENTERY. 133 Every time we breathe an undulating motion is commu- nicated to the whole intestines, which facilitates their action, but which could not take place unless they were capable of gliding easily and freely over each other. The peri- toneal coat, being strong, extensible, and elastic, is very useful also as a support to the other coats. The peritoneal coat, after forming the outer covering of the intestine, represented by the dotted line round the circle I in the subjoined figure, is continued from it in the form of a double membrane (represented by the two dotted lines)-toward the spine S, to which it is first firmly attach- ed by cellular substance; after which the folds again se- parate, each being continued or reflected, as it is called, over the whole inner substance of the cavity of the abdomen in the course shown by the dotted line, the figure itself represent- ing a transverse sec- tion of the abdomen. By this arrangement two importantobjects are attained. First, the abdominal perito- neum AP forms a soft lubricated surface cor- responding to that of the bowels themselves ; and, secondly, a firm point of at- tachment for the bowels is secured, by which they may be supported in their proper places, and at the same time ad- mit of some change of position. The floating portion of the peritoneum M, by which the attachment is effected, is called the mesentery, (from fieoog, mesos, the middle, and evrepov, enteron, intestine.) But the intestinal canal being so much longer than the portion of the spin* to which the mesentery is attached, the latter is necessarily disposed in folds con- verging toward the spine, something like the folds of a fan converging toward its narrow end. In this way the me- sentery, besides serving as a support to the gut, serves also to receive and afford protection to the numerous vessels, nerves, and lacteals which are copiously ramified on every portion, particularly of the 6mall intestines. This feature, however, will be better understood by inspecting the wood- cut on page 138, representing a portion of the bowel 11, 12 134 INTESTINE—MUSCULAR COAT as attached to the 3pines by the mesentery M M, along which the absorbent vessels or lacteals LKL are seen to pass from the gut toward the thoracic duct T D. The portion of peritoneum by which the small intestines are fixed to the spine, constitutes what is properly called the mesentery. That portion by which the larger bowel is attached is called the mesocolon, from its enclosing the colon; but in other respects the membrane presents no difference. The muscular coat is composed principally of transverse and longitudinal fibres, and its sole object here, as else- where, is to effect motion. By the alternate contraction of the two kinds of fibres, the contents of the gut are gradual- ly propelled in a downward direction, just as we see a motion propagated from one end of a worm to the other; and hence it is sometimes called the vermicular or worm- like motion, (from vermis} a worm.) Some nauseating sub-. stances, such as emetics, have the power of inverting the order of the muscular contractions, and directing the, con- tents upward instead of downward—whence vomiting ulti- mately arises. Other substances, again, have the property of exciting the natural action to a higher degree, and con- sequently propelling the contents faster downward—in other words, of purging. Rhubarb, aloes, and similar laxatives, especially when combined with tonics, act in this way, and are, consequently, best adapted for obviating the kind of costiveness which arises from imperfect intestinal contrac- tion. In a natural mode of life the muscular coat is great- ly aided in its operation by the large abdominal and thoracic muscles, brought powerfully and frequently into play during active exercise and employments. When this aid is with- drawn, as it is in sedentary people, the intestinal action often proves insufficient for the purpose; and.hence the costiveness which is so invariable an attendant on most females, literary men, and others, whose occupations deprive them of active muscular exercise in the open air. In fe- males the use of tight stays renders the free expansion of the chest and corresponding motion of the abdomen al- together impossible, and thus aggravates the evils of their sedentary mode of life. Hence also the peculiar fitness, in such cases, of the class of purgatives above alluded to, in preference to those of a saline nature, which act chiefly by stimulating the mucous surface to farther secretion. In addition to the ordinary longitudinal and transverse INTE8TINE—MUCOUS COAT. 135 fibres, the colon presents three remarkable muscular bands running along its whole length, and one of which is repre- sented on the colon in the figure on page 132. On the rectum all the three bands are seen. It is in the colon and rectum that the feculent matter accumulates before it is thrown out of the bowels, and these bands are useful chiefly by adding to their propelling power. The natural tendency of muscular fibre being to contract, it may naturally be supposed that, after the intestine is emptied, its opposite sides will come into contact, and, by thus obliterating the cavity altogether, present an obstacle to the subsequent passage of any solid matter. But, on inspecting the abdomen after death, we rarely meet with any considerable portion thus contracted ; and, in general, the whole intestines are distended to a greater or less degree, according to circumstances. The agent by which this effect is brought about, is one known more familiarly by the inconveniences and pain to which it gives rise when in excess, than by its proper uses, which are, nevertheless, important. I allude to the presence of air in the bowels, which is as necessary to their healthy action as their muscular contraction itself. Air, in fact, by its expansive energy, forms the antagonist power to the muscular coat, and serves to dilate the bowel after the requisite contraction has propelled its contents. A certain degree of distention, indeed, not only is a stimulus to farther muscular con- traction, but is useful in facilitating the passage of the subsequent portions of the feculent matter ; and hence the injection of air into the bowels in large quantity has lately been employed successfully in overcoming obstinate constipation. The mucous, internal, or villous coat of the intestine, also resembles in many respects that of the stomach. It is a soft, velvety membrane, full of wrinkles or folds through the greater part of its course, by means of which its surface is greatly increased in extent, so as to afford ample space for the ramification of the bloodvessels, nerves, and absorbents, with which it is very plentifully supplied. The cut on p. 145 will convey some idea of its appearance, as seen in the smaller intestine. So far as nutrition is concerned, the mucous coat is the truly essential part of the bowel. It alone is in direct contact with the chyme, and in its cavity the bile and pancreatic juice perform their respective parts, 136 INTESTINE—MUCOtJS COAT. and give rise to the formation of chyle, which is afterward transmitted from its surface into the general system. The peritoneal and muscular coats are useful only in affording protection, and communicating the power of propelling its contents. The mucous coat appears, on examination, to be so entire- ly continuous with the skin, that no line of demarcation can be detected between them, either at the mouth or at the anus. In structure they greatly resemble each other, and the sympathy between them is well known to be very rapid and intimate. Eruptions on the skin, for example, are almost always owing to disorder of the digestive organs ; and bowel-complaint, on the other hand, is often produced by a sudden chill on the surface. In like manner, in enor- mous eaters, like those formerly mentioned, an immense exhalation takes place from both the skin and the bowels, and in many instances the one supplies the place of the other in a considerable degree. We have seen, moreover, that in the lowest tribes of animals the digesting surfaces and skin are not only undistinguishable, but actually con- vertible into each other by the simple process of turning the animal inside out, when each will perform the function of the other as well as if it had never done anything else. In common with the skin, too, the mucous coat is charged with the double function of excretion and absorp- tion. For the former, it is eminently fitted by its plentiful supply of blood, and by the great number of minute vessels ramified on its surface, from the extremities of which the excretion takes place. It is by this channel that much of the waste matter requiring to be removed from the body is thrown out. Being poured into the cavity of the intestine from the small arterial branches, it mixes there with the indigestible residuum of the food and bile, and, united with them, forms the common fa?ces or excrement. When the blood is suddenly repelled from the surface by a chill, and thiown in upon these vessels in large quantity, the natural excretion is sometimes increased to such an extent as to constitute bowel-complaint; while, at other times, that peculiar form of action is induced which constitutes inflam- mation. The local stimulus of some kinds of food, and of many medical substances, also excites the secretion to unusual activity. Salts, for instance, have this effect, and thus often produce numerous fluid evacuations, the sub- INTESTINE—MUCOUS COAT. 137 stance or materials of which did not before exist in the bowels ; and hence the mistake into which many fall, of taking more medicine on the ground of this effect proving that much stuff was lodged in the bowels—when, in fact, it was not only removed but created by the physic. It is from exciting a fluid discharge of this description, that salino purgatives are so useful for lowering the tone of the system when that is required ; but, for the same reason, they are most improper where relaxation and debility already exist. In Asiatic cholera almost the whole fluids of the bodyare carried off by this channel, leaving the blood too thick in consistence to circulate longer through the smaller vessels. The excretions from the minute arterial branches rami- fied on the internal coat are mingled with a bland fluid from the mucous follicles, the evident use of which is to protect from injury the sensitive surface of the intestine. Occa- sionally, however, the mucous secretion becomes so abun- dant and viscid as to adhere with unusual force, and to impede the formation and absorption of the chyle, and even the action of the usual purgatives. Worms are then com- mon, and cannot be expelled, except by remedies which tend to remove the mucus in which they live imbedded. To fit the mucous coat for its office of absorption, an immense number of minute vessels, called absorbents, are ramified on its internal surface, the nature and purposes of which are analogous to those mentioned in the former volume when describing the functions of the skin.* In both structures the absorbents are small capillary or hair- sized vessels, so infinite in number that at least one goes to every little point or papilla. Those which open upon the inner surface of the smaller intestines, and which suck in or absorb the chyle, are called lacteal absorbents, or simply the lacteals or milk-vessels, (marked LLLL in the subjoined wood-cut,) from the white colour of the chyle shining through them and giving them the appearance of vessels full of milk. In that part of the gut they are so numerous that every minute point of the villous coat may be seen, by the aid of a microscope, to contain one with its mouth open to receive the chyle as fast as it is formed. Even in the colon the absorbents are numerous ; but, as all traces of chyle have there disappeared, they are much fewer than in the smaller intestines. In the colon they • Principles of Physiology, &c, chap. ii. 12* 138 INTESTINE—MUCOUS COAT—ITS ABSORBENTS. serve chiefly to remove the more watery portions of the intestinal contents, by which means the faeces are rendered TD more solid and less bulky, and, therefore, better adapted for being retained for a time without inconvenience. It some- times happens that, when food or medicine cannot be swal- lowed in the usual way, life is preserved by injecting it into the bowels ; in which case the absorbents of the large gut become active, and carry it into the system. Strong soups, milk, opium, laxatives, and other remedies are often admi- nistered in the same way, when any reason exists against giving them by the mouth. There are absorbents in every structure of the body, because there are everywhere waste particles to be taken up and removed; but, except in the case of the lacteals, their contents are limpid or colourless, and hence in other places they are called lymphatics : in almost every other respect, however, the two classes of vessels are analogous to each other. The peculiar property by which the minute lacteal ves- sels imbibe or take up the white chyle is not well understood. From the fact in physics, that liquids rise in capillary tubes, the inference has been drawn that absorption in living INTESTINE—MUCOUS COAT—ITS ABSORBENTS. 139 Vessels also takes place from capillary attraction. But in the animal body the application of the principle is undoubt- edly modified by the properties peculiar to organization, and one of the most remarkable proofs of this is the circum- stance of the absorbent vessels in different situations having, to some extent, a specific adaptation to the qualities of the substances upon which they are severally destined to act. At one time, indeed, it was supposed that the principle of exclusive adaptation was so complete that every absorbent vessel was permanently shut to everything except its own peculiar object, and that, from amid many elements, each selected its own with unerring tact. But of late j it has been proved that the absorbents are less rigidly discriminating than was previously supposed, and that substances are readily taken up by them which Nature never intended them to receive. In mix- ing madder with the food of fowls, for example, for the purpose of dying their bones, the colouring mat- ter of the root is taken up without difficulty by the absorbents along with the chyle, although madder was certainly never intend- ed to be their natural sti- mulus. But even admit- ting this latitude in its fullest extent, there still exist a fitness and pecu- liarity of relation between the absorbents and their proper objects, which ren- ders the latter more acces- sible to them than to any foreign body. The lacteal vessels are 140 INTESTINE—CONVERSION OF CHYLE INTO BLOOD. most easily seen an hour or two after a meal; because they are then fully distended with chyle, even in their smaller branches. The latter, indeed, may then be distinctly traced proceeding from the different portions of intestine, and gra- dually coalescing into larger trunks, as seen at L L in the figure on p. 138. These, again, terminate in the vessel called the thoracic duct, (the beginning of which is seen at TD in the same figure,) by which the chyle is conveyed al- most in a direct course along the spine, and which "is repre- sented at D D D D in the cut on p. 139. On its arrival at the upper part of the chest, the thoracic duct crosses over and opens into the subclavian vein S, just before the latter reaches the right side of the heart, so that the chyle is there poured into the circulating current of the venous blood. Such is the course of the chyle. But the lacteal absor- bents, in their progress from the intestine to the thoracic duct, pass through the small glandular bodies called the mesenteric glands, (M G, p. 138,) where some change, the nature of which is not at all understood, is produced upon the chyle, but which seems, nevertheless, to be of importance to its constitution. Where these glands are hardened and enlarged, as they often are in scrofulous children with large prominent bellies and thin bodies, nutrition is greatly im- paired, although the appetite and stomachic digestion re- main comparatively unaffected. The reason why the chyle is carried so far, to be poured into the current of the venous blood just before the latter reaches the right side of the heart, is, on consideration, not less obvious than cogent. Chyle itself is not fitted to become a constituent part of the animal frame. Before it can become so it must be converted intoblood; and this can be effected only by exposing it to the action of the air in the air-cells of the lungs in a state of intimate mixture with the venous blood. This admixture, again, is ensured by the gradual way in which the chyle advances along the thoracic duct and falls into the circulating current almost drop by drop ; and it takes place just before the dark blood has finished its course, and is again subjected to complete aeration in its passage through the lungs. As explained in the former volume, this aeration is so indispensable to the renovation of the old and the formation of new blood, that whenever it is rendered imperfect, either by obstructions in the lungs themselves or by the absence of a sufficiently INTESTINE—CONVERSION OF CHYLE INTO BLOOD. 141- pure air without, the result is invariably injurious to health; because the blood, being no longer properly constituted, becomes incapable of furnishing a healthy stimulus and nourishment to all the parts of the body. Hence the rapid " decline" which follows the appearance of pulmonary consumption, and other diseases affecting the structure and interrupting the functions of the lungs. Everybody knows as a fact that bad air is hurtful, and that wasting disease of the lungs is attended with rapid loss of flesh and strength ; but the manner in which these effects are produced is not so familiarly known. Yet, in a practi- cal point of view, a knowledge of the principle is highly im- portant. Properly considered, respiration is in reality the completion of digestion. The stomach may convert the food into chyme, the small intestines may convert the chyme into chyle, and the absorbents may take up the latter and duly convey it into the circulating system ; but, unless it undergo the necessary change in the air-cells of the lungs, it will not constitute good blood nor afford due nourishment to the body. Hence it is that those among the working classes who are much confined in an impure and insalubri- ous atmosphere, even when plentifully supplied with food, are generally thin and ill nourished ; and hence those who, along with good digestion, have small narrow chests and very limited respiration, are commonly found to be consti- tutionally lean—while those who, along with good digestion, have amply developed lungs and free and powerful respira- tion, are at the same time remarkable for proportional vigour of nutrition and stoutness of body. It is on this ac- count that in chronic pulmonary disease recovery is always to be distrusted, unless, along with the disappearance of the prominent symptoms, restoration of the ,lost flesh occurs. If nutrition remains impaired, however great the relief may be in other respects, there is reason to believe that the lungs are still so extensively diseased as to injure their functions, and that, on the application of any fresh exciting cause, the dormant mischief will resume its activity. In such cases, when stomachic digestion is sound, a full diet generally over-stimulates the system, by pouring into the blood more chyle than the lungs are able to assimilate ; in consequence of which it is diffused over the whole body in an imperfect state of preparation. The mucous membrane is, like the skin, well provided 142 INTE3TINS—DUODENUM • with nerves, and has a mode of sensation peculiar to itself. Every villous point, indeed, has a nervous fibre ramified on it, to give it the necessary sensibility to its own stimuli. It is true, we are not conscious in health of the impressions made on the intestinal nerves; but this, as already shown in describing the stomach, is a privilege and not a defect. They recognise their appropriate stimuli, and cause the necessary actions to follow without requiring aid from the will. But when they meet with substances which ought not to be there, such as pieces of undigested food, or foreign bodies which have no natural relation to their constitution, they immediately indicate uneasiness, and excite the mus- cular contractions to rid them of the offending cause. To secure full and natural action in the intestinal canal, several principal conditions are thus necessary, failure of any of which may impair their activity. The first condition is well-digested chyme and chyle ; the second, a due quan- tity and quality of mucous and vascular secretions from the villous coat; the third, full contractile power in the mus- cular fibres of the intestine, and free action of the abdominal and respiratory muscles; and the last, a due nervous sensi- bility to receive impressions and communicate the necessary stimulus. And hence, when the bowels act imperfectly, it is of importance to ascertain to what cause the inability is to be ascribed, that an appropriate treatment may be devised. Such are the general structure and uses of the intestinal canal; but there are modifications in its individual portions, on which it may be right to offer a few additional remarks. We shall begin with the duodenum. The duodenum (from duodeni, twelve, being considered equal in length to twelve finger-breadths) commences at the pyloric orifice of the stomach, from which it crosses over under the lower surface of the liver, toward the right side ; it then descends in front of the right kidney, and there form- ing a second curve, it proceeds again toward the left, and a little beyond the spinal column terminates in the, jejunum. It thus describes a course like the letter C, and has its con- vexity turned toward the right, while the pancreas or sweet- bread (P P) lies in the space enclosed by its concavity. To enable the reader to form some notion of the relative position of these parts, I have introduced a wood-cut on the next page, showing the situations and appearance of the different organs after the intestines, as in the figure on 144 INTESTINE—DUODENUM. page 132, have been removed from the body. The letters LLLL point out the inferior surface of the liver, a little raised from its natural position to show the gall-bladder G and the pancreas P P, round the right end of which the duodenum is curved. S indicates the spleen, with a vacant space over it, in which the stomach lies. The kidneys K K lie one on each side of the spine; and the two pipes UU are the ureters which convey their secreted fluid to the bladder B. The letters A A indicate the great artery, (the aorta,) through which the nutritive blood descends to supply the bowels and lower parts of the body ; and V V mark the corresponding vein, (the cava,) by which the dark blood returns from the extremities toward the heart. R is the beginning of the rectum or straight gut seen at Y Y in the cut on page 132. The duodenum, being'thus in the immediate vicinity of the spine, is fixed firmly down in its position by the con- necting membrane, and is not left to float loosely in the cavity of the abdomen or belly. Had it not been tied down in this way, it would not only have acted by its weight as a continual drag upon the stomach and disturbed its functions, but likewise have been constantly altering its own relation to the pancreatic and hepatic (or liver) ducts, and thereby affecting the flow of their respective fluids into its cavity, by which the chyliflcation would have often been interrupted. The duodenum is much smaller in diameter than the stomach, but large than the jejunum or ileum; and its muscular coat is also thicker. From its size and the im- portance of the changes effected in it, it has been con- sidered by some as a secondary stomach or ventriculus succenturiatus. Its mucous coat, which has a soft velvety feel, presents a greater multitude of the folds or plaits al- ready described, and which have for their object to extend its surface and delay the passage of the chyme. Some notion of their appearance may be formed from the sub- joined wood-cut. These folds or ruga are called valvula conniventes or folding valves, and are inherent in the na- ture of the mucous coat, and not produced by mere folds of the whole thickness of the intestine, consequently they exist even when the latter is distended. They are com- paratively few in number in the part of the duodenum near the stomach, and gradually multiply in the course DUODENUM AND LIVER. 145 downward till they arrive at the maximum of developement at its lower end and in the jejunum : they again diminish in the ileum, and disappear altogether in the large gut. The bloodvessels and nerves of the duodenum are extremely numerous, and indicate the importance of its functions. The duodenum serves to receive the chyme as its issues from the stomach, and to prepare it for the farther changes which it is about to undergo. But as other organs, namely, the liver and pancreas, are directly concerned along with the duodenum in effecting ehylification, it will be proper to take a cursory view of them also before describing the rest of the intestine. The liver (LLLL, p. 143) is a very large glandular body lying under the short ribs of the right side, immedi- ately below the diaphragm or midriff, to which it is attach- ed by strong ligamentary bands, which sustain its weight and keep it in its place. Its office is to secrete the bile, but it differs in one important particular from every other secreting organ. Its secretion is derived, not, as in other instances, from the arterial or nutritive blood, but from the venous or exhausted blood, which is collected from all the abdominal organs, and transmitted through it for this purpose on its way back to the heart. From this pecu- 146 THE LIVER—BILE—ITS NATURE. liarity it is legitimately enough inferred, that the liver served the double purpose of providing a fluid indispensable for ehylification and the proper action of the bowels as or- gans of excretion, and also of separating from the venous blood useless> or spent materials, which require to be thrown out of the system. The influence of the bile as a stimulant to the bowels is proved by the fact, that cos- tiveness ensues when it is deficient in quantity, and an opposite condition when the secretion is redundant, as during the heat of autumn. Bile is a bitter, viscid, greenish-yellow fluid, the taste and general appearance of which are familiar to most people, and the office of which in the animal economy must be one of no small moment, if it be justly charge- able with even a tenth part of the catalogue of human ills which are laid to its account. Its secretion seems to go on continuously ;- but the quantity produced depends much on the amount of venous blood which is circulating through the liver at the time. Hence, in health, it is always greatest soon after a meal; because, as we have already seen, the supply of blood in both the arteries and the veins connected with digestion is then at its maximum. But as the secretion of the bile is constantly going on, and its presence in the duodenum' is required only when the latter contains chyme, a contrivance becomes requisite for storing it up in the interval, to be ready for use when wanted. This is effected by the small shut sac or bag G, named the gall (or bile) bladder, which adheres to the lower surface of the liver, and is always most full after a fast of some duration. The bile contained in the gall- bladder is generally more viscid, dark, and bitter than that which proceeds directly from the liver—apparently from the absorption of its more fluid parts. It is in this bag that gall-stones, as they are called, are sometimes form- ed, and it is their passage through the narrow tube in which it terminates that causes the acute pain so often complain- ed of in that affection. From the livrr the bile is conducted into the duodenum through a membranous tube, of about the diameter of a qjuill, and which is called the biliary or hepatic duct. Iri its course a similar pipe, called the cystic dhtct, (from Kvarig, kystis, a bladder,) from the gall-bladder, unites with it into one trunk, like the two limbs of the letter Y ; and THE PANCREAS—ITS JUICE. 147 diis trunk enters the duodenum by an orifice common to it and the pancreatic duct: In the healthy state bile is to be found only in the duode- num, and not in the stomach ; although one would suppose the contrary from the familiar way in which we speak of the stomach being oppressed with bile, and of our being " very bilious." When vomiting is excited, either artifi- cially or by illness, we, no doubt, often bring up plenty of bile. Sometimes this bile has been existing in the stomach and causing nausea ; but very often it is brought into the stomach solely by the inverted action which constitutes vomiting, and was consequently placed there by the very remedy which is supposed to have cleared it away. The process of vomiting is accompanied by an inverted action of the intestinal canal, whereby it propels its contents up- ward instead of downward, and thus the bile is, as it were, forced from the duodenum into the stomach, instead of being propelled downward and expelled in the usual way. Hence, in sea-sickness, for example, the first fits of retching generally bring up nothing but food or mucus—the real contents of the stomach—and it is only after continued straining that bitter bile makes its appearance. In the healthy state fat or oily food often causes the presence of bile in the stomach, as if its aid were necessary there for the accomplishment of digestion. The pancreas, or sweetbread, P P, is a large oblong gland, which lies across the spine, and secretes a fluid almost identical with the saliva. Its duct, as stated above, enters the duodenum along with the biliary duct, so that the two fluids meet at their entrance, which takes place at the first curvature of the intestine, at the distance of about one-third of its whole length from the stomach. The bile and pancreatic juice thus poured out together are both requisite for the formation of chyle, and appa- rently modify the action of each other. The bile being somewhat of an unctuous nature, and the pancreatic juice somewhat alkaline, their union forms a kind of sapona- ceous compound, which is less irritating and more easily incorporated with the chyme than pure bile. In proportion as the chyme is formed and expelled from the stomach, it is received into the duodenum, where it probably undergoes some farther change even before ar- riving at the entrance of the biliary and pancreatic ducts 148 INTESTINE—JEJUNUM—ILEUM. From the numerous folds or wrinkles which line the inner surface of the duodenum and impede the motion of its contents, and also from the intestine itself being more fixed down, and less subjected to the influence of the movements of respiration, the progress of the chyme along its surface is very slow. Every particle of chyme is thus allowed to receive its share of the bile and pancreatic juice as it proceeds on its course, and time is afforded for the requisite changes taking place. By simply stating that, in the duodenum, the chyma becomes mixed with the two fluids just mentioned, and that the result is its separation into a fluid, milky, and nutritive portion, named chyle, which is absorbed by the lacteals, and a darker yellow-coloured thickish mass which remains in the bowel, we communicate to the reader almost every- thing that is known on the subject. Theories and conjec- tures could be added, but scarcely any facts of a very positive nature. The remainder of the small intestine,, namely, the jeju- num (from jejunus, fasting or hungry, because it is generally empty) and the ileum? (from ei'Aeu, eileo, I twist or turn about,) marked RSSSS in the cut on p. 132, are merely continuations of the duodenum, and have precisely tha same number of coats and the same general structure. Their inner surface presents the same kind of folds or ruga, whereby the extent of the mucous membrane is increased, and ample space given for the ramifications of bloodvessels and the origin of the absorbents by which the chyle is sucked up and carried into the system. Exhalation or exudation also goes on from their surface, and in bowel-complaints often becomes so excessive as in a few days to reduce the patient to the extremity of emaciation and weakness. As the contents of the jejunum and ileum advance, the proportion of chyle in them becomes smaller and smaller, and the residual matter becomes more and more consistent, yellow, and fetid—approaching, in short, to the ordinary appearance of excrement when expelled from the body. In accordance with these changes, the number of absorbent vessels and the distinctness of the villous folds gradually diminish as we proceed downward, till, on arriving at the termination of the ileum in the colon or great gut, they altogether disappear, and the contents assume the colour, smell, and appearance- by which excrement or feculent matter is characterized. '' INTESTINE--COLON. 149 The division between the small and great intestines is indicated, not only by marked differences in their diameter and external appearance, but also by an internal valve placed between them, the object of which is to prevent the contents of the colon from following a retrograde course and return- ing to the ileum. It is also worthy of notice, that the colon is not a gradually enlarged continuation of the ileum. On the contrary, the latter enters the side of the colon almost at right angles to its course, at a little distance from its commencement. The small portion of the celen which thus lies at one side of the entrance of the ileum, and which has, of course, no opening at its extremity, is thence called the caput caecum, coli, or blind head of the colon, or simply the caecum. Its position is at T in/the figure on p. 132, but it is hidden by the folds of the ileum. The colon, (from kol?i.ov, coilon, hollow,) or great gut UUU in the same figure, constitutes not more than one-fifth in length of the intestinal canal. It begins at the lower part of the right side of the belly, at T in the cut on page 132 ; rises upward on the same side toward the liver; crosses over to the left side in contact with the stomach ; descends along the left side ©f the abdomen ; makes a turn at UWX like an italic s, (and hence called sigmoid flexure,) while lying on the left haunch-bone ; and lastly, terminates in the rectum or straight gut YY at the anus. Being fixed by local attachments, the colon remains always in the same situation, and thus describes a figure not unlike a square, s in the centre of which lie the whole of the smaller intes- tines. In the cut referred to the left portion is hidden behind them. The diameter of the colon is about double that of the small intestines. In structure it is analogous to them, having three coats ; but the valvula connivent.es, or folds of the mucous coat, are no longer to be seen, and with them all traces of chyle and chyle-bearing vessels also disappear The colon serves more as a reservoir for waste or excre- mentitio'us matter than as a vital organ. Absorption is carried on from its inner surface, but through the medium of lymphatic absorbents and minute venous ramifications, and not of lacteals. Hence not only food, but medicine, are frequently administered by being injected into the rec- tum, and life has been saved in this way when nothing could be given by the mouth. 13* 150 INTESTINAL DIGESTION OF VEGETABLE FOOD*. The passage of the intestinal contents from the stomach downward is affected chiefly by the peristaltic or vermicular motion, that is, the successive muscular contraction of the middle or fleshy coat, already frequently adverted to ; and this, in its turn, is greatly aided by the constant, but gen- tle, agitation which the whole digestive apparatus receives during the act of breathing, and during exercise of every description. In inhaling air into the lungs, the diaphragm is depressed, the bowels are pushed down, the walls of the belly yield, and it becomes protuberant. When air is thrown out from the lungs, the diaphragm rises into the chest, the bowels follow, and the belly becomes flattened and drawn in. The stomach and bowels are thus placed between, and receive a never-ending impulse from, two bodies differently placed and in continual motion. During exercise breathing is deeper, and muscular contraction greater in power and in extent; and hence the assistance afforded is also increased. Those who take no exercise, or who have the chest and bowels confined and bound down by tight stays and bandages, lose this natural stimulus, and have, in consequence, the bowels obstinate and troublesome. The great extent and capacity of the intestinal canal in herbivorous animals, and others living on bulky and innu- tritions food, have been already noticed and their reason explained. Perhaps it ought to be added, that an additional reason is the fact, that the digestion of vegetable nutriment is not, like that of animal food, completed in the s'tornach, but in the intestines. It is familiarly known, for example, that when digestion is weak, fruits and fresh vegetable ali- ments often pass through the bowels very little changed ; and that, even at the best, they are digested more slowly than animal food. On examining the bodies of animals at different intervals from the time of feeding, the distinguish- ing fibrous structure of vegetable food is observed to dimi- nish in proportion to its distance from the stomach, and it does not finally disappear till it is nearly arrived at the end of its course. From this it has been inferred, that the digestion of vegetable matter is only partially accomplished in the stomach, and that it requires the aid of the intestinal juices for its completion. Delabere Blaine arrives at the same conclusion, from considering the peculiar digestion of the horse. In the horse the stomach is a simple bag, of very moderate size, and yet that animal not only can INTESTINAL DIGESTION OF ANIMAL FOOD. 151 drink a gallon or two of water at a time, but can eat a much larger quantity of hay or grass than its stomach seems to be capable of containing. Blaine explains this, by stating that, in reality, oats and hay are not long retained in the stomach, and that, after receiving the requisite supply of gastric juice, and undergoing its influence to some extent, they are gradually propelled toward the duodenum, where their digestion is continued, but not completed till long after being subjected to the action of the bile and pancrea- tic juice, and passing through the remainder of the small intestine. It is owing, he adds, to this speedy evacuation of the stomach that the horse is less inclined to drowsi- ness, and less incommoded by active exercise, soon after meals, than almost any other animal. The late Baron Dupuytren had several opportunities of observing something analogous to this in the humam sub- ject. He had, at various times, under his care, patients in whom an opening into the intestine had taken place at different distances from the stomach, and through which the intestinal contents readily escaped. On giving several kinds of food at one meal, he remarked that they presented themselves at the wound in the inverse order of their di- gestibility. Thus, fresh vegetables always made their appearance first, still retaining much of their peculiar structure ; while animal substances either did not appear at all, or were so much altered in appearance as scarcely to be recognised. In the natural evacuations, however, the vegetable structure was generally imperceptible ; so that a considerable change must have taken place on it as it advanced through the bowels, after passing the seat of the wound. Londe had occasion to remark the same thing in a lady in whom an opening into the intestine existed. When she ate cutlets or chicken, digestion was so far advanced before they reached the opening, that their identity could not be recognised. But when she ate spinage, carrots, or vegetable soups, these articles arrived at the orifice scarce- ly at all changed. In this patient also vegetable substances passed rapidly out of the stomach. Thus salads, prunes, apples, and spinage made their appearance at the opening in about an hour; while the remains of animal food never appeared in less than three hours. Londe, indeed, lays it down as a principle, that where the wants of the system are not great, the digestion or alteration of innutritious sub- S52 CONCLUDING REMARKS. stances, such as stewed or raw fruits, carrots, &c, " begins only in the ileum" He adds, that he "has always seen these substances resist the action of the acid and mucous juices of the stomach, as well as that oT the pancreatic and biliary secretions."* From the circumstance of vegetable aliment containing Utile nourishment and muck indigestible matter, it naturally happens that a larger quantity of refuse remains to be thrown out of the bowels when it constitutes the chief part of the diet, than when animal or farinaceous food, which contains much nourishment and little indigestible matter, is used. Hence, as a general rule, the bowels act more freely, or are more open, in the former than in the latter case ; and hence the common saying, that milk, eggs, jellies, and meat are binding. They have the appearance of being so, chiefly because they are almost wholly absorb- ed. But as neither the stomach nor the bowels are adapt- ed in structure for very concentrated food, such articles cannot be long used with advantage. Brown and rye bread, and fruits, are in repute for relieving a costive habit of body, and their usefulness is explicable on the same principle. They leave a large residue to be thrown out of the system, and this residue forms the natural stimulus of the bowels, and, consequently, excites them to freer action. This effect is probably aided also by the stimulus which the indigestible refuse imparts to the mucous glands, increas- ing the lubricating secretion, and giving additional facility to the propelling powers. In the preceding exposition of the structure and func- tions of the organs of digestion many omissions necessari- ly occur, and many questions of much intrinsic interest are passed over with very little notice. But a minuter survey was incompatible with both the objects and the limits of the work. My great aim was, not so much to extend the bounds of physiology, but to turn to a useful purpose what is already known in regard to one of its most important departments, and to interest a larger class of people in its cultivation. If I have said enough to make the points of doctrine on which I have touched intelligible to the ordinary reader, and to impress him with a just sense of their prac- tical value, 1 shall have accomplished the utmost I have sought to attain. x * Londe, Elemens d'Hygiene, tome ii., p. 16. 153 PART II. THE PRINCIPLES OF DIETETICS VIEWED IN RELATION TO THE LAWS OF DIGESTION. CHAPTER I. TIMES OF EATING. The selection of food only one element in sound digestion—Othe* conditions essential- Times of eating—No stated hours for eat. ing—Five or six hours of interval between meals generally suffi- cient ; but must vary according to circumstances—Habit has much influence—Proper time for breakfast depends on constitu- tion, health, and mode of life—Interval required between break- fast and dinner ; best time for dinner ; circumstances in which lunch is proper ; late dinners considered ; their propriety depen- dant on mode of life—Tea and coffee as a third meal; useful in certain circumstances—Supper considered—General rule as to meals—Nature admits of variety ; illustrations ; but requires the observance of principle in our rules. Having, in the first part of the present work, traced the progress of the food through its successive stages of pre- paration for becoming a constituent element of the animal frame, and examined the structure and nature of the vari- ous organs engaged in digestion, I shall now endeavour to turn the exposition to account, by making it, as far as pos- sible, subservient to a closer and more rational observance of the laws of digestion, and to a better adaptation of diet and regimen to different ages, sexes, and constitutions, than that which is generally prevalent. I am deeply sensible of the imperfections which will abound in this part of the work ; but, at the same time, I am so strongly impressed with the urgent importance of the subject, and with the success which will infallibly attend its farther investigation on sound physiological principles, that I consider the like- lihood of personal failure to be of secondary importance, when compared with the benefits which will accrue to society from the exertions of others whose labours may be more profitably directed by an acquaintance with the guiding principles unfolded in these, pages. According to the popular notion of dietetics, the selection of the proper kind of food seems to be considered the only condition required for the enjoyment of healthy digestion. Hence medical men are constantly questioned whether this or that article of diet is good or bad for the stomach, while 154 INTERVAL BETWEEN MEALS curiosity rarely, if ever, extends so far as to inquire in' what circumstances the one ought to be preferred to the other, or whether Nature has annezed any other conditions to sound digestion which also it may be expedient to know and to observe. In reality, however, the choice of aliment is but one out of many circumstances which require to be attended to ; and it often happens that the same food which is digested with ease when the collateral conditions are ful- filled, will remain for hours on the stomach unaltered when they are neglected. It is essential, therefore, that these conditions should be known and attended to. Even when we have ascertained what kind of food is most suitable for the individual, the limes and quantities in which it ought to be taken are still important points to be determined. However well regulated the diet maybe in other respects, if we eat either more or less frequently,,or in larger or smaller quantity, than the wants of the system require, diges- tion and nutrition will speedily suffer. It will be proper, therefore, to begin our inquiry by explaining the principles according to which the times of eating ought to be ar- ranged. Times of Eating.—If we look to the exposition of the objects of eating already given in treating of appetite, it will be obvious that Nature intended us to regulate our meals by the demands of the system, and not to eat at stated hours as a matter of course, whether nourishment be required or not. If we are engaged in occupations which induce a rapid expenditure of material, or if growth is going on so fast as to require unusually ample supplies, food ought to be taken both more frequently and in larger quan- tity than when we are differently circumstanced ; or, in other words, food ought to bear a relation to the mode of life and circumstances of the individual, and not be determined by a reference to time alone. In reality, however, the animal economy is constituted with so strong a tendency to periodical activity, that, after growth is completed and the waste of the system becomes in some measure definite and regular, as great an approxima- tion as possible oujrht to be made to fixed times of eating. In general little difficulty and much advantage attend the arrangement; because, where the mode of life is nearly the same throughout a whole class, the same waste will go on, anu^ consequently, the demand for a supply of nourish- TO BE DETERMINED BY CIRCUMSTANCES. 155 ment in all the individuals composing it will be felt at nearly the same intervals, subject only to such variations as are induced by original differences of age and constitution. As regards each class, therefore, regularity in the recurrence of meals is not less natural than advantageous ; and it is only when we attempt to combine a given order of diet with different and even incompatible modes of life, that Nature refuses to sanction the arrangement. So strong, indeed, is the tendency to periodicity in the system, that appetite returns for a time at the accustomed hour, even after the mode of life, and consequently the wants of the system, have undergone a change; and if not gratified it again subsides. Ultimately, however, its call becomes too urgent to admit of being a second time disregarded. Nature has accorded to man considerable latitude in fix- ing the interval within which the demands of appetite must be gratified, and in this provision has obviously had in view the infinite variety of circumstances in which he may be placed in the discharge of his numerous duties. As a ge- neral rule, and in mature age, five or six hours should elapse, between one meal and another—longer if the mode "of life be indolent, shorter if very active, as during the efferves- cence of childhood and youth. Digestion occupies from three to five hours, according to the nature and abundance of the meal and the state of health ; and the stomach re- quires an interval of rest after, the process is finished, to enable it to recover its tone, before it can again enter upon the vigorous performance of its function. Appetite, accord- ingly, does not begin to show itself till some time after the stomach has become empty ; and if food be taken before it has recovered its tone by repose, the secretion of gastric juice and the contraction of its muscular fibres will be alike imperfect, and digestion consequently become impaired. If, again, food be taken before the digestion of the preced- ing meal be completed, the result will be still worse ; be- cause the whole of the gastric juice which the stomach can secrete being already engaged in the solution of the first meal, the one subsequently taken will necessarily remain unsupplied, and, consequently, liable to undergo the same chemical change—fermentation—which would occur in it if exposed out of the stomach to an equal degree of heat and moisture. And, therefore, Dr. Kitchener, in alluding to the advantages arising from giving the stomach 156 INFLUENCE OF TRAINING ON EATINO. an occasional rest, truly and forcibly remarks that, " unless the constitution is so confoundedly debilitated that the cir- culation will not run alone, abstinence is the easiest— cheapest—and best cure for the disorders which arise from indigestion or intemperance." In these cases, indeed, abstinence is to the exhausted stomach what repose is to the wearied muscles, and hence the benefits which result from its judicious observance. The interval between each meal ought to be longer or shorter in proportion to the quantity eaten, and to the age and more or less active habits of the individual; and it would be absurd to fix the same standard for all. A young growing person requires frequent supplies of nourishing food to furnish the materials of growth. For a similar reason a strong labouring man, whose system is subjected to great waste from being engaged all day in hard work, will require not only more frequent but more copious meals than an indolent and sedentary man ; and those who eat very little will-require to eat at shorter intervals than those whose meals are heavy. An invalid on restrict- ed diet may thus require to eat every four hours, where, with a more copious diet, once in six hours would be suffi- cient. Some, indeed, are so constituted as to require only one or two abundant meals in twenty-four hours. Early training exercises great power over the stomach as well as over the mind. In savage life, where the sup- plies of food are precarious, a single meal may be copious enough to serve for two or three days together. The monks of La Trappe make it part of their religion to eat only once a day, and nothing but vegetable food—unless when sick, in which case milk is allowed ; but it is long f before they become reconciled to the restriction. Some years ago I travelled for three days in a French diligence with one of the order, then on his way from Italy to the Monastery of La Trappe, near Nantes, and observed that he scrupulously adhered to his single meal. He had a dispensation, however, authorizing him to eat animal food and use wine during his journey ; and I was surprised at the extent to which he availed himself of the permission, by devouring at one time a store sufficient to last for a week instead of a day. But, as in the case of the boa constrictor in similar circumstances, a deep lethargy im- mediately succeeded, and it was not till four or five hours BEST TIME FOR BREAKFAST. 157 afterward that his almost apoplectic features became again animated and expressive : iong before next meal, however, his renewed appetite betrayed itself by expressive glances toward the comforts of the breakfast-table. Nature, then, has fixed no particular hours for eating, but has established principles easy of discovery and of ap- plication, by which, with a little reflection, we may readily adapt our regimen to our respective ages, constitutions, and habits. According to these principles, whenever the mode of life is uniform and the expenditure of the system pretty equable, fixed hours for meals may be safely adopt- ed ; but where these are irregular, the intervals between meals ought also to vary, and the safest guide will then be the recurrence of true appetite—a sure sign that the system is in need of a supply. Meals, then, ought to be early or late in proportion to the habits of the individual. If, adhering to the order of Nature, we work by day and sleep by night, an early break- fast, an early dinner, and an early evening meal will un- doubtedly be the most conducive to sound digestion and the enjoyment of health. But if, against the laws of Na- ture, we rise from bed late in the forenoon, reserve our activity till late in the afternoon, and do not go to sleep till two or three hours before daybreak, then assuredly the late breakfasts and dinners of the fashionable society of the present day will be the best for our comfort that can be devised. Here the grand error is in the unnatural mode of life which renders very late meals necessary. But so long as such a mode of life is persisted in, it would only add to its injurious effects to attempt to combine it with the observance of the early hours of eating suited to those who live in conformity with nature. This principle is often lost sight of by medical men. The proper time for taking breakfast ought to be regu- lated by the individual constitution and habits. Those who eat supper ought not to breakfast till one or two hours at least after rising ; but persons who dine late and eat nothing afterward, and whose digestion is vigorous, require breakfast sooner. Individuals of a delicate frame are often unable for either bodily or mental exertion in the morning, and are invariably injured by any attempt at active exercise or serious thinking before breakfast; but strong healthy persons, and invalids in whom digestion is slow rather 158 SUSCEPTIBILITY GREATEST BEFORE BREAKFAST. than diseased, may enjoy, and even be benefited by, two or three hours of activity before their morning meal, es- pecially if accustomed to eat supper. Keeping the phy- siological principle in view, a little experience will enable any one to decide what time is the most suitable for himself. As a general rule, perhaps, breakfast about half an hour or an hour after rising will be found most beneficial; but those who rise very early will do well to follow the French custom of taking a cup of coffee or tea, and bread, on getting up. and reserve their appetite for a more substantial breakfast three hours later. This is an invaluable rule for students, who often seriously impair their digestive func- tions by studying for hours in the morning, regardless of the craving of the system for nourishment and support. If exposure of any kind is to be incurred in the morn- ing, whether to the weather or to the causes of disease, it becomes a matter of much importance that breakfast or some substitute for it should be taken previously. It is well known that the system is more susceptible of infec- tion, and of the influence of cold, miasma, and other mor- bid causes, in the morning before eating than at any other time ; and hence it has become a point of duty with all naval and military commanders, especially in bad climates, always to give their men breakfast before exposing them to morning dews or other noxious influences. - Sir George Ballingall even mentions a regiment quartered in New- castle, in which typhus fever was very prevalent, and in which, of all the means used to check its progress, nothing proved so successful as an early breakfast of warm coffee. In aguish countries, also, experience has shown that the proportion of sick among those who ate exposed to the open air before getting anything to eat, is infinitely greater than among those who have been fortified by a comforta- ble breakfast. Where there is any delicacy of constitu- tion, the risk is of course increased. The cause of this susceptibility in the morning is not difficult to he discovered. It arises from the craving ac- tivity of the absorbents excited by the wants of the system, and the length of time which has elapsed since the preced- ing supply. If we suppose the previous meal to have taken place at six o'clock in the evening, the process of nutrition, the various secretions, and the exhalation of waste matter from the lungs, kidneys, and skin, must have ABSORPTION MOST ACTIVE IN THE MORNING. 159 been carried on for the twelve to fifteen hours between that time and the usual hour of breakfast upon the nourishment taken in during the preceding day. The result is, that the stomach, duodenum, and upper intestine, from which chiefly fresh nutriment is obtained, have been for some time en- tirely empty, and are, consequently, without any means of supplying the loss which the system has sustained during the night. In these circumstances, if food be taken, the absorbents, refreshed by repose and stimulated by want, act vigorously, and imbibe the chyle as fast as it is formed. But if legitimate food be denied to them, the same prone- ness to energetic action will impel them to imbibe any morbid or other agent which may be presented to them. When the system is fully replenished, on the other hand, the natural stimulus of the absorbents is withdrawn, and, consequently, noxious effluvia, even when present in the air, are less likely to be imbibed than under opposite cir- cumstances. It is from this constant relation between the wants of the system and the state of the absorbents that our first daily meal is almost universally of a more fluid and less substantial description than any of the subsequent ones, an the great loss of fluid by exhalation during the night causes a natural demand for liquids in the morning; while our active exertion and loss of solids during the day create a proportionate demand for a more substantial repast in the afternoon. The function of absorption, then, is at its highest pitch of activity in the morning, simply because every part of the frame is craving for a supply to repair the losses which it has sustained ; and if the body be exposed to miasma or other impurities, they will be much more easily and speedily absorbed by the skin, the pulmonary membrane, and the stomach, before eating, than after the absorbents have been supplied with their legitimate food. This is the true theory of the greater susceptibility of infection and other poisonous influences when the stomach is empty. So rapid is absorption from the stomach in the morning, that 1 have repeatedly seen nine tumblers of a saline mi- neral water taken at eight o'clock, and a very hearty break- fast finished within half an hour after the water was drunk ! When in bad health a few years ago, I observed almost equal expedition in my own person. I took half a pint of ass's milk at seven o'clock, and, in consequence of cough- 160 DELICATE PERSONS SHOULD BREAKFAST EARL*. ing violently, was frequently seized with vomiting and retching within twenty minutes after taking it; but only twice or thrice was any portion of the milk perceptible, al- though the stomach was entirely emptied. This was even more remarkable than the other case, inasmuch as milk undergoes digestion, which vteter does not. In allusion to this rapidity of absorption, Sir Francis Head, in speaking of the quantity of the chalybeate waters swallowed of a morn- ing at the Brunnens of Nassau, humorously remarks, that "one would think that this deluge of cold water would leave little room for tea and sugar; but, miraculous as it may sound, by the time I got to my ' Hof there was as much stowage in the vessel as when she sailed: besides this, the steel created an appetite which was very difficult to govern."* In setting out early to travel, a light breakfast before starting is a great protection against colds and subsequent fatigue or exhaustion. I am quite aware that robust and healthy men can and do take much active exercise before breakfast with apparent impunity, if not benefit, and I have often done so myself; but experience ultimately taught me that I became sooner exhausted on continuing the exertion through the day, than when I began by eating a little. During the first winter of my studies in Paris, I regularly attended the surgical visits at the Hotel Dieu, which began at six o'clock in the morning and lasted tiff nine or fre- quently half-past nine. Not being then aware of the prin- ciple under discussion, I ate nothing till my return home ; but I felt more weariness before the day was done than the mere exertion ought to have produced. At last, on noticing for a time the regularity with which many of the work-people passing along paid their respects at a small Bhop, the only one then open, where fancy rolls were sold, along with wine and brandy, I thought of following their example to the extent of trying how far a roll would add to my comfort. I soon found great reason to be pleased with the expedient; and discovered that I was not only less exhausted during the day, but more able to follow the lecture which concluded the visit, and in possession of a keener appetite for breakfast at my return ; and ever since I have acted on the principle now inculcated, and with marked benefit. I was then astonished at the regularity * Bubbles from the Brunnens of Nassau EXPOSURE MOST HURTFUL BEFORE BREAKFAST. 161 with which the Parisian workmen seemed to take their morning allowance of brandy on their way to their labours, apparently for the very purpose of getting that wholesome energy which they ought to have sought in food alone. During the prevalence of cholera both here and on the continent, it was often remarked that a large proportion of the attacks occurred in the morning, in persons who had gone to bed apparently well. Chronic invalids and persons of a delicate habit of body are also familiar with the fact of the animal heat and general vigour diminishing toward morning. When reduced in strength by pulmonary com- plaints, I often passed the night in comparative comfort, sure to awake about four or five o'clock with a feeling of chill and absence of animal heat, which I could not dissi- pate till after receiving sustenance. From these facts, the general inference is clearly war- ranffd, that delicate persons ought to have some kind of food soon after rising, and that even those who are robust will act wisely in not exposing themselves unnecessarily to fatigue, infection, or other morbid causes, without having previously supplied the wants of the system, either par- tially by a cup of coffee, tea, or milk, or entirely by a regu- lar breakfast. Where fever, for example, is in a family, the danger of infection will be much greater to a person going directly from his own bed to the bed-side of the pa- tient, than to one who first takes the precaution of drinking were it only a cup of coffee. I have elsewhere noticed the safety which Captain Murray obtained for his crew in the West Indies, partly by attention to this rule; and have likewise referred to the experience of Sir George Ballingall in the prevention of fever by a similar expedient. In boarding-schools for the young and growing, who ' require plenty of sustenance and are often obliged to rise early, an early breakfast is almost an indispensable con- dition of health. On the continent, in similar establish- ments, seven o'clock is the common hour for breakfast, especially in summer. In recommending what I conceive ought to be the general rule, let me not be understood as wishing to extend it so far as to advise those whose constitutions admit of two or three hours' activity before breakfast, to abandon what experience proves to be beneficial to them. My only wish is, to help those who are in doubt as to choosing the plan 162 BEST TIME FOR DINNER. which is most likely to be of advantage, and to relieve those who are already suffering from ignorance. The morning meal being comparatively a light one, and the stomach being then in high vigour, digestion goes on briskly, so that appetite revives within a shorter time than after the more substantial dinner. Accordingly, in all na- tions and classes of society not perverted from the course of nature, a longer interval than five hours rarely elapses between breakfast and dinner. Our forefathers dined at noon, as our sailors continue to do at the present day. Over no small portion of the continent of Europe the same primitive hour is still adhered to ; and among the labouring population of Great Britain one or two o'clock is the com- mon dinner-hour, eight or nine being that of breakfast. Even the rich manufacturers of Manchester and other English towns continue to this day to dine at one o'clock ; and the very universality of a mid-day meal among those who rise early, is itself a strong presumption in favour of its propriety, and of its being in harmony with the laws of the animal economy. To prevent business from interfering unduly with diges- tion, it was formerly the custom in Edinburgh to shut up shops and counting-houses for two hours in the middle of the day ; and in Switzerland I have seen the same practice followed. The members of the family being then assembled, relaxation and enjoyment take the place of the cares of the world ; and the result is highly satisfactory. The appetite is keen enough to induce them to eat with zest all that Na- ture requires, while it wants the resistless force which is given by a fast of eight or nine hours. There is, conse- quently, slower mastication, less cramming, and a much earlier return of the aptitude for business ; while at the same time the mental and bodily faculties are refreshed by the interruption of their accustomed labour, and the affections cherished by healthful domestic intercourse taking place before too much weariness is induced to permit of its being enjoyed. In England such weariness is a very common occurrence. The parent and husband, exhausted by the eager pursuit of wealth during the livelong day, returns home in the evening jaded and harassed, and little able to take pleasure or interest in the enjoyments of his wife and family. Hence, indeed, too often arise indifference and unhappiness between those whom Nature has formed as if on purpose to suit each other. BEST TIME FOR DINNER. 163 In enterprising commercial communities—in London and Liverpool, for example—it is a common practice to hasten away to the counting-room immediately after an early breakfast; to remain there in active employment from nine or ten o'clock in the morning till six o'clock in the evening, and then to hurry home to a late dinner at six or seven o'clock ; by which time the vital functions have become so far exhausted as to create a strong desire for indulgence in something stimulating both in food and drink. If this desire be gratified, immediate relief will be obtained, and a tempo- rary feeling of comfort pervade the frame; but nothing can be more erroneous than to regard this as a proof of the indul- gence being beneficial. The organization soon gets accus- tomed to the stimulus ; its susceptibility becomes impaired by the frequency with which the latter is administered ; and in a short time indigestion is the inevitable consequence. The evils attendant on this course of life are not unfre- quently aggravated by the preposterous means resorted to for their prevention. Having some vague notion that ex- ercise improves digestion, and not being at all aware that there is an improper as well as a proper time for taking it, many persons, after being exhausted by seven or eight hours' confinement to the counting-house, proceed to take a walk of four or five miles before going home to dinner, and thus utterly throw away the little strength that was left to them, and are filled with disappointment on finding their appetite and digestion worse than before.* Dr. Paris mentions the case of a clerk in a public office who brought upon himself all the horrors of dyspepsia and melancholy by following this plan. He breakfasted at nine, went to his office at ten, continued there till five, walked till seven, and then dined. He was cured in six weeks, by adopting a more rational regimen and dining at three, o'clock. Many females and delicate persons injure their powers of digestion by delaying their exercise till the system is too much exhausted to profit by it. In boarding-schools, from the desire which is felt to have all the lessons over before allowing any play, the same error is often committed, and with pernicious effects on the health of the pupils. As a general rule, then, not more than five hours ought to intervene between breakfast and dinner. If the mode * Respecting the proper regulation of exercise, see The Princi- ples of Physiology, 10th edition, chapter vi. 164 BEST TIME FOR DINNER. of life be such as involves great activity in the open air, or the period of life be one of rapid growth or filling up, (as during youth or convalescence from illness,) the interval may with propriety be shortened ; whereas, if the mode of life be sedentary, and unattended wiih much activity of nutrition, the interval may be ci>n-id"r»bly protracted with- out much inconvenience. Much also ought to depend on the natural rapidity or slowness of digestion. In some constitutions ehylification gojs on so slowly that the indi- vidual can pass with ease eitjht or ten hours without food ; whereas, in others it is so rapid that a fresh supply becomes necessary in half the time. Spnllanzani himself was an example of the former kind ; for in him digestion went on so slowly that he was unable for study till five or six,hours after even a very spare dinner The proper rule in every case is, to take dinner at such an interval after breakfast as the return of healthy appetite indicates, whether that interval be longer or shorter than the average specified. That, according to this rule, the general time for dinner ought to be somewhere about five hours after an ordinary breakfast, is evident from the almost universal return of appetite at the end of such an interval, and from the fact that many, through sheer inability to resist longer the wholesome cravings of nature, are in the regular practice of eating dinner at that time, but, to save appearances, give it the name of luncheon; by which means they hold themselves entitled to the enjoyment of a second and more substantial dinner later in the day. Invalids, dyspeptics, and all who, possessing vigorous digestion, wish to retain it, will do well to follow the in- tentions of Nature, and observe the intervals which she has appointed. Those who disregard them, and still digest without difficulty, have reason to be grateful to Providence ; but they may rest assured that they will longer enjoy (heir privilege, and better evince their gratitude, by regulating their conduct according to the ordinary laws of the animal economy, than by presuming too much on their supposed exemption from trie bad consequences of their habitual infringement. Supposing nine o'clock to be the hour of breakfast, the natural dinner-hour would thus be two o'clock ; and such, accordingly, is that sanctioned by the most extended ex- perience, and which ought to be adhered to by all whose BEST TIME FOR DINNER. 165 occupations will admit of its observance, and who wish to enjoy the highest health of which they are susceptible. Artificially arranged, however, as society now is, whole classes of the community, from business and other causes, find it impossible to dine till much later in the day. The question then comes to be—As we cannot implicitly follow the system laid down by Nature, what is the nearest approxi- mation which we can make to it 1 Ought we to eat nothing till we can find time to dine at five, six, or seven o'clock; or ought we rather to take a light luncheon at the natural time, about one or two o'clock, and delay eating a more substantial meal till the later hour at which alone we can find leisure to digest it 1 From the exposition already given, the reader will have no difficulty in determining that the latter is the preferable plan. If we leave the stomach too long empty,, its powers, as well as those of the system at large, are liable to become impair- ed from exhaustion; ahd, therefore, when dinner cannot be taken earlier than seven or eight hours after breakfast, most people will find it advantageous to partake of some slight refreshment in the meantime—enough to blunt the keenness of appetite, but not entirely to destroy it. When the individual is exposed to much bodily exertion in the open air, or is at the period of rapid growth, a portion of animal food, or an ordinary luncheon, taken in moderation, may be allowable, and even requisite ; but where the habits are sedentary and the constitution formed, a bit of bread or biscuit, and a glass of water, will be far more serviceable. Many people, from want of any better occupation, make a pastime of filling their stomachs every forenoon at the pastry-cook's, with as little regard to its powers and neces- sities as if digestion were meant merely as an appendage to taste ; and think themselves entitled to complain of their defective appetites, and the great discomfort which attends the subsequent indigestion of a heavy dinner. To relieve the weakness, arising not from exhaustion but from the oppression of satiety, they resort to wine, as if by adding fuel to the fire they could hope to extinguish the flame ! Even in fashionable life the superiority of Nature's ar- rangements over those of man is so far acknowledged, that it is an almost universal rule for children to dine in the middle of the day ; and there cannot be a doubt that the practice is attended with manifold advantages to the young, 166 BEST TIME FOR DINNER. although, as regards their moral training, these would be greatly increased were they to associate at meals with their parenis, instead of being left entirely to the company and management of servants. Here I cannot refrain from earnestly soliciting the atten- tion of the reader to the injury inflicted on the young by the irrational mode of life and education to which they are now subjected. As growth and nutrition are in them in their highest activity, it follows that at no period of life is strict adherence to the laws of the animal economy of so much moment, because, if the youthful system does not receive at the proper intervals the supplies of food of which it stands urgently in need, it must necessarily be impaired in tone, and become more liable to the inroads of disease. The completed and compact frame of an adult may resist for a time delay or irregularity in its supplies, but the undeve- loped and susceptible organization of the young suffers from the very first, and the evil increases in proportion as the aberration from the order of Nature is repeated. Hence reason, affection, and enlightened benevolence all concur in enforcing a strict adherence to an early dinner-hour for the young. On no account whatever ought it to be delayed beyond one or two o'clock. And yet, if we examine the customs of society, especially in the middle and higher ranks resident in towns, we find the school occupations so irrationally arranged, that, while the children are obliged to breakfast early, even in winter, to reach them in time, most of them find it impossible to dine till five or six o'clock— eight or nine hours after their first meal, instead of four or five. And when stunted growth, feeble digestion, delicacy, or bad health results as the natural consequence of exhaus- tion, instead of ascribing it to its true cause—the depri- vation of sustenance—and trying to cure it by a better regulation of the diet, it is usual to leave the evil to do its worst, and to content ourselves with complacently lamenting the degeneracy of the age, and boasting of the marvellous constitutions and hardihood of the children of our day, whom neither wind nor weather could hurt. If it were a favourite colt or dog whose training we were superintend- ing, the folly of shutting it up all day in a confined atmo- sphere, and denying it food at proper intervals, would stare us in the face. But, in our vain conceit, we act as if degra- dation were implied in the admission that in man health and BEST TIME FOR DINNER. 167 growth are regulated by the same physiological laws as in animals, and as if we were better pleased that disease and death should follow than that we should study and obey the laws which God himself has appointed for our guidance. The evil, however, is the source of much suffering and disappointment; and as it cannot be corrected until the public is rendered fully aware of its existence and influence, it cannot be too often brought under its notice, or too strongly condemned. The teacher alone has not the power of providing a remedy. The concurrence and co-operation of the parent are indispensable ; but both combined could easily effect such a distribution of the time and business of the school, as to leave at least a couple of hours in the middle of the day appropriated to dinner and play after it in the open air. It is no valid objection to say that in winter the day is too short to allow the " sacrifice " of so much time. The shorter it is, the greater is the necessity for making the most of it by adequate attention to the laws of health. The real " sacrifice " of time is when health is im- paired and progress retarded by undue confinement and depri- vation of exercise in the open air. The very shortness of the day, indeed, implies that we should employ the hours of darkness in in-door occupations, and make the most of the daylight' by going out while we have it; and I have no doubt that, as society advances, this truth will be felt and acted upon to the great advantage and delight of the young. An additional, and with right thinking people an irresis- tible, reason for reforming this error in education is, that, while it injures the physical system, and in delicate consti- tutions seriously affects the health, it is scarcely less hurt- ful to the mind, for which the sacrifice is made. Experience bas shown that the excessive cultivation of the intellectual faculties in the young to the disregard of the laws of the physical organization, is productive of evil even to the in- tellect. When schooling and tasks are continued daily for many successive hours, the attention flags and the vigour of the mind becomes impaired instead of being increased. In this w iy the progress made is in the long run much smaller, and acquired at a much greater risk of health and life, than when appropriate intervals are allowed, not only for eat- ing meals at the times required by the wants of the sys- tem, but also for the enjoyment of adequate muscular exer- cise in the, open air. In some schools, where a more 163 BEST TIME FOR DINNER. rational system has been tried, where the confinement to school has been lessened by one-half, and the time for meals and exercise has been doubled, as well as arranged on sound physiological principles, the results have been not only improved health and increased physical activity, but also more rapid intellectual progress and a more perfect developement of mental vigour. In the one case the mind is exhausted by the continued and monotonous strain upon the attention, and the body from want of exercise, food, and pure air. In the other the mind is strengthened by strong calls which rouse and agreeably stimulate attention, while the body also gains in vigour from receiving nourishment at the right time, and obtaining that muscular exercise in the open air without which health cannot long be preserved.* Supposing it to be made an imperative condition of .our social existence that we shall rise after mid-day, and not go to bed till a late hour in the morning, the present fashion of dining at seven or eight o'clock becomes much more rational than is commonly imagined by those who declaim against it without regard to the concomitant circumstances. It is, no doubt, most absurd and hurtful for a man who rises at seven or eight o'clock, breakfasts at nine, and goes to bed at eleven, to delay dining till seven in the evening ; but it by no means follows that seven is a bad dinner-hour for a person who rises at twelve or one o'clock, breakfasts at two, and goes to bed at three in the morning. The inter- val between the breakfast at one and dinner at seven o'clock is the same as between breakfast at nine and dinner at three, namely, six hours—which is little more than enough. The error lies not in the hours chosen for meals, but in the utter perversion of the whole system oj living, by which night is converted into day, and the business of life is postponed five or six hours beyond the time appointed by the Creator for its performance. So far from the late dinner being hurt- ful in such circumstances, it would be perfectly proper if the mode of life which leads to it were itself imperative. Under the present perverted system, accordingly, it is only the sti- mulus and support which the late dinner affords that enable the victims to withstand the fatigue even for a single week. No one has a stronger sense of the injury done to society by the wide departure from the laws of Nature by which its * The reader will find this subject more fully discussed in the tenth edition of The Principles of Physiology, &c. BEST TIME FOR DINNER. 169 present arrangements are characterized, and no one is more anxious to contribute all that is within his power to reform them, than the writer of these pages ; but, in returning to the order of Nature, the whole mode of life must be amend- ed and brought into harmony with the laws of the animal economy ; and no real progress will be made by merely altering the horir of dinner, while the conditions which have led to the existing arrangement are left unchanged. In the country, even among the higher classes, a greater approximation to the order of Nature is observable than in towns. The inducements to sleep away the day and to be awake during the night are diminished ; bodily exercise and exposure to the open air are more indulged in ; the appe- tite becomes keener and digestion more vigorous ; and, as a necessary result, meals are taken an hour or_two earlier. But, throughout all these changes, the general feature of having some kind of refreshment, either luncheon or dinner, within four, five, or six hours after breakfast, may be pretty accurately traced. If business admits of it, and the person can then com- mand two hours of relaxation, the best plan, unquestionably, is to dine about five or six hours after breakfast. But if this be impossible, and an active exertion of mind or body must be continued for several hours longer, it will be far better to eat some light refreshment in the forenoon, and to postpone dinner, not only till business is over, but till half an hour or an hour's repose has allowed its attendant excite- ment or fatigue to subside. By this means the stomach will enter upon its duties with vigour, and the dinner be digested with greater comfort and despatch than if we sit down to table the moment our work is finished. In this way the tedious quarter of an hour preceding the announcement of " dinner " is far from being lost to the subsequent digestion. Very few people, indeed, can eat a good dinner and return immediately to bodily or intellectual labour with continued impunity. On this account, actors, for example, whose vocation requires exertion of both mind and body, almost all either dine very early, or take their chief meal at night on their return home, the latter being the more common practice. Students, literary men, and persons intently en- gaged in business, are very apt to damage themselves by neglecting relaxation at and after meals. The time for dinner ought, then, to vary according to 15 170 USES OF TEA AND COFFEE. the constitution, occupations, and mode of life of the indi- vidual ; and the nearer the whole of these can be made to approximate to the intentions of Nature, the more vigorous will be the powers of digestion, and the more complete the nutrition of the body ; and, consequently, the more easily will the stomach recover the tone which it may have lost from previous mismanagement. In attempting to cure indigestion, notwithstanding the most scrupulous adherence to the rules given for the proper selection of food, if we set at defiance all the other conditions of healthy digestion, our adherence will be of little avail. Whereas, if we fulfil the laws of our constitution, by rising from bed in the morning, obtaining a healthy appetite ana lively circulation by the regular exercise of the various functions of mind and body in a free and pure atmosphere, eating moderately, and en- joying social relaxation after our meals, digestion will be so far strengthened that no very rigid observance of any particular kind of diet will be necessary ; it being always understood, however, that we shall not exceed in quantity what the wants of the system require. It would be a waste of time to discuss gravely whether tea and coffee ought to be allowed in the evening. Custom has already decided the point, and experience has shown that, in moderation, they rather promote than impede digestion. But when strong and taken in quantity,'especially by persons of a sanguine or nervous constitution and weak digestion, they are decidedly hurtful. Many ruin their health and in- duce severe nervous depression from the abuse of strong green tea, at the very time when they profess to know no cause to which their misery can be ascribed. Literary men, artists, and actors, and other public performers who are subjected at times to great intellectual or moral excitement, also suffer very frequently from the abuse of tea or coffee. When the dinner is early—say at one, two, or three o'clock —a light meal of tea and bread in the evening is very suitable, as it saves the necessity of eating a heavier sup- per. If the individual be accustomed to much active exer- tion in the afternoon, so as to cause considerable waste in the system, and especially if he be young, a small addition of animal food may be made with great propriety to the evening meal. But. on the other hand, when the dinner is late, or little exertion is incuned after it, tea or coffee ought to be used more as a diluent than as a meal. PROPRIETY OF- A THIRD MEAL CONSIDERED. 171 The French drink a single cup of strong coffee without cream immediately after dinner, and find digestion go on all the better for it. It acts as a strong stimulant, and cer- tainly increases the feeling of comfort for the time. Like all other stimulants, however, its use is attended with the disadvantage of exhausting the sensibility of the part on which it acts, and inducing weakness. This inconvenience is not felt to the same extent, indeed, after coffee as after spirits, but still it exists ; and it is infinitely better that the stomach should be brought up to do its own work un- grudgingly, than taught to dppend upon assistance from without; and, therefore, such assistance ought to be reserv- ed for the relief of occasional exhaustion, instead of being resorted to as a regular indulgence. The French partake of a much greater variety of dishes at one meal than we are accustomed to do, and may thus require the aid of coffee to keep the stomach from actual rebellion. But the proper way to obviate this necessity, is obviously to eat a more simple and moderate meal. In determining whether a third meal ought to be taken, either as tea or as supper, the general principle already laid down will be very useful. If dinner be sufficiently early to admit of digestion being completed and of the stomach being afterward recruited by repose, and if the mode of life be active, so as to occasion a natural return of appetite before the day is done, the propriety of a third meal cannot be questioned. But if dinner be late, and there be too short an interval between it and bed-time to admit of diges- tion being finished and the appetite renewed, then every additional mouthful swallowed is sure to do mischief. The farmer who dines at two o'clock, for example, and, after walking about his fields for three or four hours in the after- noon, comes home in the evening with a genuine and un- deniable appetite, has a legitimate right to an additional supply of wholesome food before betaking himself to his couch ; because a sufficient interval has elapsed to allow the stomach to recover itself from the labour of digesting his dinner, and the continued waste of the system requires to be replaced. In like manner, the man of fashion who dines at seven o'clock, and frequents assemblies till threo or four in the morning, is well entitled to some kind of supper about one or two o'clock, and could scarcely get through his laborious duties without farther sustenance from m TIME FOR MEALS. either food or wine, or both. Even in his case six hours may thus intervene between dinner and supper ; and we know that, on an average, the digestion of a moderate meal is finished in four or five hours. The chief difference be- tween him and fhe farmer is, that the farmer reaps health and sound digestion from adhering in his hours to the insti- tutions of the Creator, and that the man of fashion impairs his constitution and enfeebles his digestion—less by the improper intervals at which he eats, than by his wide de- parture from the order of Nature in the perverse mode of life which he adopts. If, following the precepts of ultra-temperance, we dine early, live actively, and go to bed with the stomach entirely empty, we may sleep, but our dreams will scarcely be more pleasant, or our sleep more tranquil, than if the stomach were overloaded. A gnawing sense of vacuity is felt in such circumstances, which is apt to induce restlessness, and nervous impatience and irritability. I have repeatedly seen these unpleasant symptoms dispelled, and sound sleep obtained, by no other prescription than a cupful of arrow- root an hour or two before bed-time. Where tea is made to constitute a meal, supper is alto- gether superfluous, except in early life, and in the case of those who lead a very laborious existence and observe very early hours. In youth waste, growth, and nutrition are so active,- that a moderate supper is often indispensable, especially when the muscular system is freely exercised in the open air. But it ought to be of a light nature, and taken at least an hour or two before going to bed. If din- ner be taken early, and tea be used in the afternoon, not as a meal, but merely as a diluent, a light supper will be very proper. In short, the grand rule in fixing the number and pe- riods of our meals is, to proportion them to the real wants of the system, as modified by age, sex, health, and manner of life, and as indicated by the true returns of appetite; and, as an approximative guide, to bear in mind that, under ordinary circumstances of activity and health, three, four, or five hours are required for the digestion of a full meal, and one or two hours more of repose before the stomach can again become fit for the resumption of its labours. If the meal be temperate and the mode of life natural, diges- tion will be completed in from three to four hours, and TIME FOR MEALS. I?3 one hour of rest will serve to restore its tone ; but if the quantity of food be great, or the general habit3 be those of indolence, digestion may be protracted to five or six hours, and two or more be required for subsequent repose. It is, therefore, utterly absurd and inconsistent with the laws of Natnte to pretend, as many writers have done, to lay down rules which shall apply to every indivi- dual and to every variety of circumstances. As already mentioned, rules applicable to classes may be prescribed, because there is a considerable similarity in the circum- stances of all the individuals comprehended in each ; but even there numerous exceptions must occur, which can be judged only by the standard of the individual constitution. The Creator, indeed, has obviously never intended that we should be bound down to the rigid observance of a very strict order in diet ; but, to fit us for the ever-vary- ing circumstances in which we are placed, has wisely and benevolently allowed us considerable latitude, and made appetite to vary in the extent and earnestness of its de- mands in proportion to the waste to which we are sub- jected for the time. It is astonishing how rapidly a healthy frame accommodates itself even to great changes when temperance is duly observed, and a proper regard is paid to the intimations of appetite. In suiting my own mode of life to the circumstances under which I have at various times been placed, I have repeatedly, even as an invalid, made sudden changes in the hours of eating, with no farther injury than temporary dis- comfort ; but, then, I always adhered to the general prin- ciples above insisted on. It was by some of these experi- ments that my attention was first drawn to the great influ- ence of the"accessory conditions in retarding or promoting digestion. At one time, on altering my place of residence from Aix to Marseilles, I changed at once from breakfast- mo- at eight o'clock, dining at two, and taking tea in the evening, to breakfasting at eleven and dining at six. For the first few days I felt uncomfortable from waiting so long in the morning; but, by following the plan of taking a cup of coffee and a crust of bread soon after risit.g, and at- tempting no considerable bodily exertion till after break- fast, every feeling of inconvenience ceased, and the system completely adapted itself to the change. Three months afterward I embarked on the Mediterranean, and again 15* 174 PRINCIPLES ON WHICH THE NUMBER AND passed at once to breakfasting between seven and eight o'clock, dining about noon, and taking tea in the evening, which I continued to do for some time after arriving in Italy. On my way home the hours of eating were never two days the same, and yet I did not suffer. If breakfast was early, I ate it with relish. If it was late, I had re- course to a biscuit or some dried fruit early in the morn- ing, to sustain the system in the meantime, and was ready for it when it came. In the same way, if dinner was to- day at one o'clock, I took it when it was offered, and had recourse to some refreshment in the evening ; if to-morrow it was postponed till eight o'clock, which sometimes hap- pened, the refreshment came in the forenoon, and a mode- rate meal was taken in the evening. In these changes, however, it will be remarked, that the laws of digestion were, in reality, much less infringed as to time than one might imagine from merely hearing that I dined one day at noon and the next day at eight o'clock in the evening. At whatever hour the meal was taken, the real, wants of the system were supplied when they manifested themselves in the form of appetite, and the re- quisite intervals were observed. If a substantial breakfast was taken at eight o'clock, then a corresponding interval elapsed before another meal followed at one or two. If, again, the morning allowance was trifling, then the real breakfast followed at an interval correspondingly short, namely, at eleven o'clock. So also with dinner. And if dinner was at one o'clock, tea followed at the distance of six or seven hours ; whereas, if dinner came at six or seven o'clock, a refreshment preceded and nothing follow- ed it, and the results were comfort and sound digestion. If, however, we yield unguardedly to the impulse of appe- tite in travelling, and eat and drink plentifully instead of temperately, no arrangement of hours that we can make will render our situation either pleasant or healthful. While, therefore, it seems to be obvious beyond a doubt, that those who live according to the laws of Nature and begin their activity with the morning, should breakfast betimes, dine early in the day, and take a lighter meal in the evening, and that those who do so will reap a reward in health and vigour of mind and body unattainable to the same extent by those who live differently, and convert night into day—it would be not less hurtful than absurd TIME OF MEALS OUGHT TO BE DETERMINED. 175 tu prescribe the same hours for meals to all, whatever their periods of activity and whatever their modes of life; and I cannot help thinking, that it is the preposterous at- tempt to generalize too much which, losing sight of true" principle and the modifications whicn it requires in indivi- dual cases, ha-s brought dietetic precepts into disrepute, and led to the belief that the rules laid down are merely arbi- trary assumptions, resting on no solid foundation in the human constitution, or in the designs of our Creator. As experience is the best guide to knowledge, I may be allowed to add, that, when travelling on the continent in health and strength, I suffered more from feverish fa- tigue and stomachic discomfort, induced by ignorant in- fringement of the laws of digestion, than I ever afterward did, even from more continued exertion when travelling as an invalid under a better regulated system of diet. I did not, in either case, make any exception to the meals which awaited our arrival at the inns, or to the hours at which they were served. The chief difference was, that, when well, I ate till my appetite was fully satisfied, under the notion that, in travelling, a full diet is necessary to enable one to withstand the fatigue ; and that, as an in- valid, on the other hand, I ate more sparingly, and, if the regular meal was much later than usual, had recourse to biscuit, fruit, or a slice of cold meat, as an intermediate refreshment, to prevent the stomach becoming exhausted from too long a fast. Following the dictates of experience, I have long adhered to the latter plan, and am convinced that few who have tried both will long prefer the former. CHAPTER II. ON THE PROPER QUANTITY OF FOOD. Quantity to be proportioned to the wants of the system—Appetite indicates these—Cautions in trusting to appetite—General error in eating too much—Illustrations from Beaumont, Caldwell, Head, and Abercrombie—Mixtures of food hurtful chiefly as tempting to excess in quantity—Examples of disease from excess in servant-girls from the country, dressmakers, &.c.—Mischief from excessive feeding in infancy—Rules for preventing this— Remarks on the consequences of excess in grown persons- Causes of confined bowels explained—And necessity of fulfilling the laws which God has appointed for the regulation of the animal economy inculcated. The next important step in the regulation of diet is, te determine the quantity which ought to be eaten. 176 TOO MUCH FOOD IS USUALLY TAKEN. To ensure easy digestion and sound health, the quantify of food ought always to be proportioned to the wants of the system ; but this can be done only by a constant reference to the constitution and circumstances of the individual, and not by attempting to lay down any standaru as admitting of universal application. We have seen that, where waste is great and growth active, an abundant supply of food is required, and that, is accordance with this relation, it is in such circumstances that the desire for food is most keenly felt. Generally speaking, appetite is a safe guide as to quantity ; but, in fol- lowing its dictates, we must take special care neither to eat so fast as to prevent it from giving timely intimation that we have had enough, nor to confound the mere gratification of taste, or the yearning of a vacant mind, with the natural craving of unsatisfied want. Dr. Beaumont's remarks on this subject are characterized by so much soundness of judgment, that no- apology can be required for soliciting the attention of the reader to the fallowing very pertinent extract from his work : " There is no subject of dietetic economy," says Dr. Beaumont, " about which people err so much as that which relates to quantity. The medical profession, too, has been accessory to this error, in giving directions to dyspeptics to eat until a sense of satiety is felt. Now, this feeling, so essential to be rightly understood, never supervenes until the invalid has eaten too much, if he have an appetite, which seldom fails him. Those even who are not other- wise predisposed to the complaint, frequently induce a di*- eased state of the digestive organs by too free indulgence of the appetite. Of this fact the medical profession are, generally, not sufficiently aware. Those who lead seden- tary lives, and whose circumstances will permit of what is called free living, are peculiarly obnoxious to these com- plaints. By paying particular attention to their sensations during the ingestion of their meals, these complaints may be avoided. There appears to be a sense of perfect intelli- gence conveyed from the stomach to the encephalic centre, which, in health, invariably dictates what quantity of ali- ment (responding to the sense of hunger and its due satis- faction) is naturally required for the purposes of life ; and which, if noticed and properly attended to, would prove th© EAQtit salutary monitor of health, and effectual preventive INDICATIONS OF A SUFFICIENCY OF FOOD. 177 of disease. It is not the sense of satiety, for this is beyond the point of healthjul indulgence, and is Nature's earliest indication of an abuse and overburden of her powers to re- plenish the system. It occurs immediately previous to this, and may be known by the pleasurable sensation of -perfect satisfaction, ease, and quiescence of body and mind. It is when the stomach says enough, and is distinguished from satiety by the difference of the sensations—the former feel- ing enough—the latter too much. The first is produced by the timely reception into the stomach of proper aliment, .in exact proportion to the requirements of Nature, for the perfect digestion of which a definite quantity of gastric juice is furnished by the proper gastric apparatus. But to effect this most agreeable of all sensations and conditions—the real Elysian satisfaction of the reasonable epicure—rtimely attention must be paid to the preliminary processes, suca, as thorough mastication and moderate or slow deglutition. These are indispensable to the due and natural supply of the stomach at the stated periods of alimentation ; for if food be swallowed too fast, and pass into the stomach im- perfectly masticated, too much is received in a short time, and in too imperfect a state of preparation to be disposed of by the gastric juice. " The quantity of gastric juice, either contained in its proper vessels or in a state of preparation in the circulating fluids, is believed to be in exact proportion to the proper quantity of aliment required for the due supply of the sys- tem. If a more than ordinary quantity of food be taken, a part of it will remain undissolved in the stomach, and pro- duce the usual unpleasant symptoms of indigestion. But if the ingestion of a large quantity be in proportion to the calls of nature, which sometimes happens after an unusual abstinence, it is probable that more than the usual supply of gastric juice is furnished ; in which case the apparent excess is in exact ratio to the requirements of the economy, and never fails to produce a sense of quiescent gratification and healthful enjoyment. A great deal depends on habit in this respect. Our Western Indians, who frequently undergo long abstinence from food, eat enormous quantities, when they can procure it, with impunity."* * Experiments and Observations on the Gastric Juice and Phy- siology of Digestion, by William Beaumont, M.D. Reprinted with notes by Andrew Combe, M.D. Edinburgh, 1838, pp, 54-56. 178 rNTEMPERANCE IN EATINO If the purposes for which eating is necessary be kept ire mind, the keen appetite and vigorous digestion observable in growing youths, and in those who undergo much active) exercise in the open air—and the weaker appetite and fee- bler digestion observed during the middle period of life,, especially in persons of sedentary habits—will appear to be in strict harmony with the wants of the system in the res- pective circumstances. But, from no attention being paid by either the old or the young to the principle by which the supply of nourishment ought to be regulated, and the hasto with which every one labours to appease the cravings of hunger, it may be affirmed, as a general fact, that mankind eat greatly more than, is required for their sustenance ; and the indigestion thereby induced is a salutary provision of Nature to prevent the repletion which would otherwise- ensue-. « Sir Francis Head, in his humorous book entitled Bubbles from the Brunnens of Nassau, by an Old Man, expresses his astonishment at the " enormous quantity of provisions '* which the invalids and sojourners at these watering-places u so placidly consume;" and, after noticing " the heavy masses which constitute the foundation of the dinner, and the successive layers of salmon—fowls—puddings—meat again —stewed fruit—and, lastly, majestic legs of mutton—which form the lighter superstructure^" he adds, " Nothing which. this world affords could induce me to feed in this gross manner. The pig which lives in his sty would have some excuse, but it is really quite shocking to 3ee any other ani- mal overpowering himself at mid-day with such a mixture and superabundance of food." (P. 71.) In another page he Teturns to the subject, and quaintly enough remarks, " that almost every malady to which the human frame is subject is, either by highways or byways, connected with the sto- mach ; and I must own, I never see a fashionable physician mysteriously counting the pulse of a plethoric patient, or,' with a silver spoonon his tongue, importantly looking down his red inflamed gullet, (so properly termed by Johnson ' the meat-pipe,') but I feel a desire to exclaim, ' Why not tell the poor gentleman at once—Sir, you've eaten too much, you've drunk too much, and you've not taken exercise- enough !' That these are the main causes of almost every one's illness, there can be no greater proof than that those •avage nations which live actively and temperately hav» A PREVAILING ERROR IN SOCIETY. 179 only one great disorder—death. The human frame was not created imperfect—it is we ourselves who have made it so ; there exists no donkey in creation so overladen as our stomachs; and it is because they groan under the weight so cruelly imposed upon them, that we see people driving them before them in herds to drink at one little brunnen." (P. 91-2.) Our supposed " Old Man " is by no means singular in his opinions. The celebrated Roman physician Baglivi, who, from practising extensively among Catholics, had ample opportunities of observation, mentions that in Italy an un- usually large proportion of the sick recover during lent, in consequence of the lower diet which is then observed as part of their religious duties. This fact is at once a testi- mony in favour of temperance, and a proof of the assertion that excess in quantity is a prevailing error in society. Professor Caldwell, of the United States, in ene of his vigorously conceived and very instructive essays, inveighs eloquently against the intemperance of his countrymen in eating as well as in drinking, and tells them that one Ame- rican consumes as much food as two Highlanders or two Swiss, although the latter are among the stoutest of the race. " Intemperate eating," says he, " is perhaps the most universal fault we commit. We are all guilty of it, not occasionally, but habitually, and almost uniformly from the cradle to the grave. It is the bane alike of our infancy and youth, our maturity and age. It is infinitely more com- mon than intemperance in drinking ; and the aggregate of the mischief it does is greater. For every reeling drunkard that disgraces our country, it contains one hundred gluttons —persons, I mean, who eat to excess and suffer by tha practice." " How, indeed," he afterward exclaims, " can the case be otherwise, while children and youth are regular- ly taught, hired, bribed, or tempted to over-eat themselves from their birth ! Do you ask me for evidence in proof of this charge1? Go to our dining-rooms, nurseries, fruit- shops, confectionaries, and pleasure-gardens—go even ti obvious truth. The evil attending their unnecessary use may not be felt at the moment, but, nevertheless, it is there ; and for demonstrative proof of the fact we are again indebt- ed to Dr. Beaumont. On examining St. Martin's stomach after he had been indulging freely in ardent spirits for several days, Dr. Beaumont found its mucous membrane covered with erythematic (inflammatory) and aphthous (ulcerous) patches, the secretions vitiated, and the gastric juice di- minished in quantity, viscid and unhealthy ; although St. Martin still complained of nothing, not even of impaired appetite. Two days later, when the state of matters was aggravated, " the inner membrane of the stomach was un- usually morbid, the erythematic appearance more extensive, the spots more livid than usual; from the surface of some of them exuded small drops of grumous blood ; the aphthous patches were larger and more numerous—the mucous cover- ing thicker than common,' and the gastric secretions much more vitiated. The gastric fluids extracted were mixed with a large proportion of thick ropy mucus, and a considerable mucopurulent discharge slightly tinged with blood, resem- bling the discharge from the bowels in some cases of dysen- tery. Notwithstanding this diseased appearance of the stomach, no very essential aberration of its functions was manifested. St. Martin complained of no symptoms indi- cating any general derangement of the system, except an uneasy sensation and a tenderness at the pit of the stomach, and some vertigo, with dimness and yellowness of vision, on stooping down and rising again ; had a thin yellowish brown coat on his tongue, and his countenance was rather sallow ; pulse uniform and regular, appetite good ; rests quietly, and sleeps as usual."* I have marked part of this quotation in italics, because it cannot be too attentively considered by those who contend that the stimulus of spirits is not injurious to the stomach or general health, unless where the mischief shows itself by palpable external signs. Here we have incontestable proof, that disease of the stomach was induced, and going on from bad to worse, in consequence of indulgence in ardent spirits, although no prominent symptom made its appearance, and St. Martin was, in his general habits, a healthy and sober man. And if such be the results of a * Beaumont's Experiments and Observations, &c., reprinted by Andrew Combe, M.D., p. 250. 262 STATE OF STOMACH IN FEVER. few days of intemperance in a person of a sound constitu- tion, it is impossible to deny that continued indulgence must be followed by more serious evils, whether these show them- selves from the first by marked external signs or not After a few days of low diet and the use of mild diluents, the coats of St. Martin's stomach were seen to resume their healthy appearance ; the secretions became natural, the gas- tric juice clear and abundant, and the appetite voracious. Dr. Beaumont adds, that, in the course of his experiments, diseased appearances of a similar kind were frequently observed—generally, but not always, after some appreciable cause. " Improper indulgence in eating and drinking has been the most common precursor of these diseased condi- tions of the coats of the stomach. The free use of ardent spirits, wine, beer, or any intoxicating liquor, when conti- nued for some days, has invariably produced these morbid changes. Eating voraciously or to excess, swallowing food coarsely masticated or too fast," " almost invariably produce similar effects, if repeated a number of times in close suc- cession." (P. 252 ) These observations require no com- ment ; their practical bearing must be obvious to all who are willing to perceive it. Dr. Beaumont had also frequent occasion to remark, that, when stomachic disorder, attended with febrile symptoms, was present, the mucous coat of the stomach presented dis- tinct appearances of disease. He frequently saw it, for ex- ample, red, irritable, and dry ; and, on the food touching it, no gastric juice exuded, and, consequently, any food taken lay long undigested. But after the diseased action was subdued by regimen and medicine, the gastric juice again flowed readily, and digestion went on as vigorously as be- fore. Even anger and violent mental emotions sometimes produced these appearances, and gave rise to temporary indigestion. These observations show the futility, not to say mischief, of administering food during fever and other diseases by way of supporting the strength, when, from the deficiency of the gastric juice, it cannot be digested, and can only add to the existing irritation. In this state, how- ever, bland fluids are appropriate; because they allay irri- tation, and are almost entirely absorbed, without requiring to be digested. The condition of the stomach above described, and the consequent failure and vitiation of the gastric secretion, in- EFFECT OF DRAMS. 263 duced by drinking ardent spirits, and by general intempe- rance, explain at once the miserable digestion and impaired appetite of the habitual drunkard ; and it would be well for those who are in danger of becoming the victims of the habit, were they early impressed with some of these stri- king and important truths. If it be asked whether I go the length of proscribing all fermented liquors, from table-beer upward, I answer that I do not; I merely mean that, where the general health is perfect without them, they ought not to be taken, because then their only effect is to produce unnatural excitement. But wherever the constitution or health is so deficient, or the exertions required by the mode of life are so great, that the system cannot be sustained in proper vigour without some additional stimulus, I would not only sanction, but recommend the use of either wine or such other fermented liquor as should be found by experience to support the strength, without quickening the circulation, exciting the mind, or disordering the digestive functions. If, however, 0 any of these effects be produced, I would consider its occur- rence as a proof that the stimulus is inappropriate, and can- not be too soon discontinued, or at least diminished to 3uch a quantity as shall be consistent with the ordinary action of the animal functions. It may be alleged that a glass of brandy after a heavy dinner facilitates digestion, and, therefore, cannot do harm. I admit at once, that, when we eat too much, or fill the stomach with indigestible food, a dram of brandy, from its temporary stimulus, enables us to get rid of the load sooner than we could do without it. But it seems to me.that a far wiser plan would be, to abstain from eating what we know to be oppressive to the stomach ; and that by this means we shall attain our end infinitely better than by first eating a heavy meal and then taking a stimulus, the efficacy of which is diminished by every repetition of its use. If we were compelled to exceed the bounds of mo- deration in eating, there would be some apology for our conduct. 264 CHAPTER VII. ON THE PROPER REGULATION OF THE BOWELS. Functions of the intestines—The action of the bowels bears a na- tural relation to the kind of diet—Illustrations—And also to the other excretions—Practical conclusions from this—Different causes of inactivity of bowels—Natural aids to intestinal action— General neglect of them—Great importance of regularity of bowels—Bad health from their neglect—Especially at the age of puberty—Natural means preferable to purgatives—Concluding remarks. Having now taken a general view of the objects, nature, and laws of digestion, and of the structure and rriode of action of the various organs concerned in its performance, and made ourselves acquainted with the principles on which our conduct ought to be regulated, so as to second the in- tentions of Nature for our welfare and happiness, I have only to add a few practical remarks on the proper manage- ment of the bowels, and then conclude. The proper uses of the intestines are, as we have seen, to serve, 1st, for the performance of ehylification ; 2dly, for the absorption of the nutritive chyle ; and, 3dly, as a reservoir for the indigestible residue of the food, and an outlet for both it and the effete matter which requires to be thrown out of the general system. The processes of ehylification and absorption having been treated of in a former chapter, it is in the last capacity only we have now to consider the intestinal canal. Besides the bowels, there are several other channels by which the waste materials of the body pass out. The most important of these are the skin, the lungs, and the kidneys ; and in certain circumstances, where the action of the one is impaired or repressed, the natural alliance subsisting among their respective functions, enables the rest to come to its assistance, and even for a time to supply its place. Thus, when, by continued exposure to cold, the exhalation from the skin is much diminished, the blood is thrown in upon the internal organs in larger quantity, and, as a con- sequence, the urinary secretion and the exhalation from the lungs are both increased, and full relief to the system is temporarily obtained. During hot weather, on the other hand, when the skin is in high action and perspiration flowing freely, the urinary secretion is greatly lessened. The same principle applies equally to the case of the bowels; and hence the sudden application of cold to the surface of N THE PROPER REGULATION OF THE BOWELS. 265 the body, and consequent suppression of perspiration, often increase the intestinal secretions to such an amount as to induce bowel-complaint. On the other hand, the excited action of the bowels by laxatives tends equally to diminish .the activity of the skin; and hence, indeed, one source of the cooling effect of saline purgatives administered in fever and inflammations. The bowels being thus the outlet of the indigestible portion of the food, and of waste matter from the system, it follows that in health their action ought to bear a rela- tion . to the kind of aliment used, and to the state of the other excretory functions ; and, consequently, that what may constitute healthy action at one time, and in one indi- vidual, may be very far from presenting the same character at another time, and in a different individual. If, for ex- ample, a person be fed chiefly on milk, rice, or farinaceous aliment, which is almost entirely appropriated to the pur- poses of nutrition, and leaves very little residue, the bow- els, having little to throw out, will naturally act seldomer and less fully than when the diet consists chiefly of bulky and innutritious vegetables, which leave a large portion of indigestible matter to be evacuated. Most persons are aware of the difference of effect between the two kinds of diet, but, from not being acquainted with the principle on which it depends, are apt to conclude that, because in the first case the bowels act less, therefore they ought to be assisted by laxatives. The inference, however, is by no means necessarily sound ; because the diminished intestinal action consequent on an exclusively farinaceous diet is then the natural and healthy result*; and accordingly, where such diet is required, and is not used in excess, the mere costive- ness is attended with no injury to the constitution. The proper conclusion to be drawn from it is, that the perma- nent and exclusive use of concentrated food is not in harmony with the structure and functions of our digestive and assimilating organs, and that, therefore, instead of continuing their use, and merely resorting to purgatives to excite an action for the removal of a residue which does not exist, reason requires that we should select a diet better adapted to the constitution and laws of the organiza- tion by which it is to be acted upon. The same remark applies to those who are accustomed to dine chiefly on animal food, and rice or bread, without 23 266 THE ACTION OF THE BOWELS BEARS A any sufficient admixture of herbaceous or other innutritioue substances. If, in such circumstances, the aliment ia almost entirely converted into nourishment and absorbed, it follows, as a matter of necessity, that little will remain to be thrown out of the body, and that the bowels will act less than with a different kind of diet. If the state of the constitution at the time be such as to require the exclusive use of this kind of aliment, forced action of the bowels by purgatives will not be needed, because their slowness will be natural and healthy. But if it be not, then the proper remedy is, not to excite the bowels by irritating purgatives, but to remove the cause of the intestinal inactivity by changing the system of diet. It may be answered to this, that there are many in- stances in which the stomach is unable to digest any vege- table or innutritious food, and in which, consequently, the diet cannot be altered without injury. I admit that, in the present state of society, where the laws of the animal economy are so generally disregarded, cases of this kind are common; but their number would be greatly reduced if a proper mode of life were systematically adopted, and that regard paid to the conditions of health which their in- trinsic importance deserves. There are very few indivi- duals who, when in health, and with the aid of a proper regimen, cannot digest aliment suited to the natural con- stitution of the stomach and bowels; and when such cases do occur, they constitute exceptions to the general rule, and must, of course, be treated either by the use of laxa- tives, or such other remedies as the circumstances may require. As the frequency and amount of the intestinal evacua- tions may thus vary according to the nature of the diet, without necessarily involving aiiy disturbance of health, so may they also vary according to the state of the other ex- cretions ; and hence, again, is evident the absurdity of considering the same standard as applicable alike to all persons, times, and circumstances. If, from continued ex- ertion, perspiration is kept unusually active, the excretion from the bowels may be proportionally diminished, not only without injury, but even with advantage to the health ; because, if the same waste were to go on by the bowels as before, and the increased exhalation from the skin also to continue, the system would speedily become reduced. In NATURAL RELATION TO THE KIND OF DIET. 267 consumption, for example, exhausting bowel-complaint and profuse perspiration are frequently observed to alternate, and whatever remedy is given to check the one generally aggravates the other. But if both were to run their course together, instead of singly, how much more rapidly would the system be undermined ! From this relation between the different excretory func- tions it follows that, when sluggishness of the bowels is induced by excess in another excretion, the first step ought to be to remove or diminish the unnatural stimulus which has occasioned that excess, before attempting, by means of purgatives, to force the bowels to act. If the cause which has produced the deviation from the due proportion of the excretion be left unabated, the only effect of strong laxatives will be, not to relieve, but to irritate and weaken. The mere fact of the bowels not being emptied so fre- quently as usual, is, therefore, when taken by itself, no evidence that they ought to be stimulated by medicine. Before coming to this conclusion, we ought to determine clearly whether the diminished action results from morbid sluggishness of the intestinal canal, or is the natural result of an accidental change of diet, or temporary excess in the other excretions ; because the remedy which is appropriate and efficacious in the one case, may be altogether inappli- cable to the other. Where it arises entirely from the aliment leaving little residual matter to be thrown out, the health may suffer from the diet being inappropriate, but it will not suffer merely from the diminished action of the bowels. Whereas, when the diet is of the ordinary mixed kind, and the costiveness proceeds from morbid inaction, then general derangement of the system will be induced, unless the bowels be attended, to and their natural action restored. This distinction ought never to be lost sight of. Judging from the prevalent notions on the subject, from the universal reference of all kinds of bad health to derange- ment of the stomach and bowels as their source, and from the scarcely less universal use of purgatives as remedial agents, one would be apt to suppose that, to ensure health and long life, nothing more was required than to procure, no matter by what means, an intestinal evacuation regularly every day ; and the inference would, to a certain extent, be confirmed by the acknowledged extensive utility of laxa- tive medicines. The real state of the case, however, is 268 DIFFERENT CAUSES OF INACTIVE BOWELS. not quite so simple ; and as it is of importance that it should be understood, I shall attempt to explain it as clearly as I can. We have seen that inactivity of the intestinal canal may arise from the use of too concentrated aliment, and from excess in the other exertions. In the great majority of cases, however, the cause is very different. In general, the diet is sufficiently varied and abundant, and the balance of functions sufficiently equal, to leave a considerable quan- tity of alimentary residue and effete matter to be thrown out by the bowels ; and if it is not regularly expelled, some obstacle of a different kind must exist, which, in the first place, ought to be removed, before we can expect to suc- ceed in restoring the natural action. To learn what that obstacle is, let us turn our attention for a moment to the natural means by which the intestinal evacuations are ef- fected. The progress of the intestinal contents along their canal depends, first, on their affording the necessary stimulus to excite the contraction of the muscular coat; secondly, on the assistance derived from the free action of the abdominal and respiratory muscles, not only during respiration, but during every kind of bodily exercise ; and, thirdly, on the inner surface of the intestine being duly lubricated with the mucous secretion. If any or all of these conditions be un- fulfilled, the inevitable result will be morbid sluggishness of the intestinal action, and the various consequences depen- dant on it; and hence, when the evil exists, the first point to be determined is the nature of the cause by which it is produced. As already remarked, farinaceous, gelatinous, and other concentrated aliments do not afford the requisite stimulus to the muscular fibres of the intestine; because they are in a great measure absorbed, and leave little to be thrown out. If, therefore, concentrated food be the cause of cos- tiveness, the proper remedy is to alter the diet, and to have recourse to other means only where that proves insufficient. If, again, the inactivity of the bowels proceeds from the food not being sufficiently digested, and from their contents being on this account inadequate to excite them to healthy and regular action, it follows, as a necessary consequence, that, before we can expect to obtain intestinal regularity, digestion must be improved by steady perseverance in a DIFFERENT CAUSES OF INACTIVE BOWELS. 269 proper regimen, and such other means as may be required to restore the tone of the stomach. It is in cases of this description that the practitioner is most frequently consulted. If he and the patient are satisfied with simply procuring relief, he has ready means at hand in any of the ordinary purgatives. But if a cure is their object, they must go back to the root of the evil, and begin by restoring the diges- tive organs to health as the first step toward permanent success. The observance of a proper adaptation between the quan- tity of the food and the state of the digestive organs and mode of life is, then, not less essential to the proper action of the bowels than to that of the stomach. If we eat more than the system requires, the bowels become oppressed and weakened by their load ; and it is in such circumstances that purgatives afford immediate relief by the removal of the superfluity, and, by blinding the individual to the real nature of the evil, tempt him to recur too frequently to the use of medicine. Where, however, as most frequently happens, the con- stipation arises chiefly from the absence of all assistance from the abdominal and respiratory muscles, and in part only from an inappropriate diet, the first step to be taken is again to solicit the aid of the former—first, by removing all impediments to free respiration, such as stays, waistbands, and belts ; and, secondly, by resorting to such active exer- cises as shall call the muscles into full and regular action : and the next is to proportion the quantity of food to the wants of the system and to the condition of the digestive organs. If we employ these means systematically and per- se veringly, we shall rarely fail in at last restoring the healthy action of the bowels with little aid from medicine. But if we set these natural conditions at defiance, we may go on for years, adding pill to pill, and dose to dose, without ever attaining the end at which we aim. How, indeed, can it be otherwise 1 If the Creator has so constituted us that the free play of the lungs and mus- cles is indispensable to proper intestinal action, it is in vain for us to struggle against the arrangement, and expect to substitute beneficially the stimulus of purgatives for that of the natural play of the muscles. Either we must give up our own obstinate adherence to sedentary pursuits and conform to the divine laws, or we must submit t6 the pun- 23* 270 NATURAL AIDS TO INTESTINAL ACTION. ishment inseparable from disobedience, and merely endea- vour to mitigate its severity by such partial remedies as lie within our reach. ' Where bodily weakness, or any other cause, absolutely prevents us from engaging in active bodily exertion, cor- responding moderation in eating, and continued kneading and rubbing over the region of the bowels, when used daily and persevered in till the strength be restored, are of great service in promoting their healthy action. Where great sluggishness of the bowels exists, and no exercise can be taken, the rubbing generally requires to be continued for an hour or more daily, or even twice a day. Sometimes intestinal inaction proceeds from defective mucous secretion on the surface of the internal coat, caused either by errors in diet or by local irritation. When cos- tiveness is excited in this way, a mild diluent regimen will generally remove it. It is in such cases that saline medi- cines, which act by increasing the mucous secretions, are often very useful; while aloetic and other stimulant purga- tives increase the evil by aggravating the irritation. Such being the mode of action of the bowels, and such the natural agents by which it is carried on, we can now appreciate the folly of seeking to apply the same remedy tC every kind of costiveness. no matter from what cause it pro- ceeds. If a clerk who sits motionless all day in an office, who indulges his appetite, and has no bodily exercise to facilitate respiration and give a natural impetus to the bowels, begins after a time to complain of constipation, it is not difficult to tell what is required for his cure. The first step which a knowledge of the animal functions would suggest is, to diminish the food to such a quantity as the system re- quires and the stomach can digest; the next, to use such a diet as is calculated to excite the muscular coat of the intestine to healthy activity ; the third, to seek the natural aid arising from exercise of the abdominal arid respiratory muscles ; and the last of all, to have recourse, when neces- sary, to such medicines as may for a time be required to restore the tone of the bowels, and enable them to act with- out farther assistance. The course usually adopted, how- ever, is widely different from that here described. From ignorance of the laws of organization, the patient is not aware of the extent to which he infringes them in his con- duct, and, consequently, rests satisfied with lamenting his REGULARITY OF BOWELS IMPORTANT. 271 hard fate in possessing such a bad constitution, and resort- ing to strong medicines to force that action which he feels to be essential to health, but which he will not consent to elicit by the means with which Nature has furnished him. Among the middle and higher classes very many females act on the same erroneous plan, and with equally unfortu- nate results. In them the evil is aggravated by the tight- ness of their clothing impeding almost entirely the descent of the diaphragm, and the free play of the abdominal mus- cles, in respiration. From this view of the nature and cause of costiveness it will be evident that, as a general rule, the bowels are perfectly competent to the discharge of their functions, when the conditions essential for their healthy action are duly fulfilled. And hence, whenever they become morbidly inactive, we may rest assured that, in some point or other, our own management is or has been defective; and the surest way to remedy the evil is, not to have instant re- course to medicine, but to begin by discovering and amend- ing the defect. In the rare occurrence of constipation among children and other actively employed persons, we have ample proof of the fundamental principle that the bowels do not naturally stand in need of the stimulus of medicine, but require only to be properly treated to fit them for the office with which they are charged. While, then, I entirely agree with public opinion in at- taching great importance to the proper regulation of the bowels, and in tracing much suffering to their neglect, I am only the more anxious that we should, as far as possible, follow Nature in our arrangements, and reap the benefit of her aid. If we do so, we shall not only be less frequently obliged to have recourse to medicine, but, by our knowledge of the causes of the deficient action, be greatly assisted in our selection of an appropriate kind of laxative, and thus avoid forcing the constitution too far. It sometimes hap- pens, for example, that, from debihty of the muscular coat, the peristaltic motion is insufficient to propel the contents of the intestines, even with the aid of proper diet and exer- cise. In such cases small doses of aloes or rhubarb, or other laxatives, which act chiefly by exciting the mus- cular contraction, will be sufficient to clear the bowels, especially when any mild tonic is conjoined with them; while saline laxatives, which act chiefly on the mucous coat, 272 DYSPEPSIA IN EARLY LIFE FROM may be given freely, and even cause numerous watery evacuations, and yet the real or solid contents of the intes- tines continue unremoved. In practice this often happens ; and hence the frequent mistake of supposing that there is proper passage from the bowels, when, in reality, there is no such thing. The period of life at which intestinal inactivity is at- tended with the most serious consequences is, at and for a few years after puberty. At that age a sudden change is often made from the restless activity of youth to all the stillness of a sedentary profession, without any correspond- ing alteration being made in the quantity of food consumed. The vigorous appetite, which is perfectly natural during a period of growth and great bodily activity, remains at first unimpaired, and impels the individual to eat an amount of food far beyond the present necessities of the system or the powers of digestion. The consequence is a ten- dency, not only to fulness from excessive nutrition, but to obstinate digestive disorder from the stomach and intes- tines being weakened both by want of exercise and by excess of food. From pretty extensive observation, I am confident that a large proportion of the severe dyspeptic cases attended with great derangement and imperfect ac- tion of the bowels, which occur, in what are considered regular living men, on the approach of manhood, or be- tween twenty and forty years of age, are fairly attributa- ble to this cause, and might be avoided by the exercise of a rational foresight ; and I have known several who suf- fered severely in this way for years, emphatically lament the ignorance which betrayed them into the error. There are many persons, no doubt, constitutionally too devoted to intemperance to be corrected by any such considerations ; but there are also many misled, less by the force of appe- tite than by ignorance, who may profit by the remark. After the above observations were written, I was struck with a remarkable confirmation of them in the excellent work recently published by Mr. Parker, of Birmingham, " on the stomach and its morbid states." After describ- ing the mode in which repeated attacks of gastric irritation ultimately induce disorganization of the stomach, Mr. Par- ker says, " I have had the' charge of several patients in the latter stages of gastric diseases, who have been able distinctly to trace the commencement of their complaints. NOT ADAPTING DIET TO CIRCUMSTANCES. 273 These have seldom commenced before the age of twenty-five, at the periods when they had began the habitual use of a fuller and more stimulating diet than that of the earlier periods of life. The symptoms with which they were first affected were those of simple indigestion, in its various forms of pain or distention after food, nausea, or vomiting. These have ceased at intervals, have been relieved by va- rious plans of treatment, but have shown a disposition to recur at longer or shorter intervals from dietetic errors or excesses, or from other causes, in more aggravated and obstinate forms than those in which they first made their appearance, and accompanied by sympathetic irritations in the head, heart, liver, or lungs, exhibited in the forms of giddiness, palpitations, jaundice, or cough." " Many of the patients in whom dyspeptic symptoms have commenced about the ages of twenty or thirty, have fallen victims to gastric diseases and their complications at the ages of from forty-five to fifty-five."—P. 47. Mr. Parker supports his position by numerous cases, the histories of which are de- tailed by the patients themselves, and, with the slight dif- ference that he speaks of the patients beginning the use of the full and stimulating diet at twenty-five, when, ac- cording to my observation, their error consisted rather in continuing the full diet of earlier life, we entirely agree in opinion. The effect is, however, much aggravated when, to mere excess in quantity, a stimulating quality is added, such as arises from the indulgence in wine or ardent spi- rits, common enough in young men at the age to which Mr. Parker refers. In such circumstances it is not the stomach alone which suffers. The bowels also become seriously disordered, lose their natural tone, and thus seem to demand the constant aid of medicine. In one case, arising from pure excess of eating after growth had finish- ed, four years of continued bad health in an otherwise sound constitution were the penalty inflicted before the real eause was accidentally discovered. During all that time, too, temporary relief invariably followed the use of purgatives, and seemed in some measure to point to the truth ; but fiom the mind never having been directed to the principles, its practical bearing was overlooked, and now the individual wonders that the cause did not, even at first sight, arrest the attention of his medical advisers. : In cases of this description, however, it ought to be ob- 274 REGULARITY OF BOWELS IMPORTANT. served that it is not the mere constipation which injures the health and requires to be removed. It is, in reality, to the mode of life which induces it that we ought to direct our attention; for. unless that be amended, all our efforts to preserve the health by merely removing the effect will prove insufficient. In the natural and healthy state, under a proper system of diet, and with sufficient exercise, the bowels are relieved regularly once every day. In some constitutions, however, the ordinary period is shorter or longer than this—twice a day, or only once in two days ; but such differences are unimportant when they do not proceed from morbid causes or in any way disturb the health. Habit, in this as in other operations under the influence of the nervous system, is powerful in modifying the result, and in sustaining healthy action when once fairly established. Hence the obvious advantage of observing as much regularity in relieving the system as in taking our meals, and the impropriety of at- tempting to break through the habit when once formed. Sleep seems to be favourable to the progress of nutrition, and it is apparently during the night that the assimilation of the daily food is completed, and its residue prepared for being expelled along with the other excretions. Hence there is a natural tendency in the bowels to act in the morn- ing, and we ought, therefore, to encourage it by a voluntary effort. Even the reception of breakfast into the stomach seems to act as a stimulus to intestinal contraction, and, in consequence, many persons experience the inclination im- mediately after their morning repast, and suffer if they are prevented from yielding to it. Where, either from constitutional weakness, sedentary occupation, or other unavoidable causes, the bowels are unable to act sufficiently to relieve the system without as- sistance, we have, of course, no choice but to select that which is most suitable to the circumstances and most gen- tle in its operation ; because, if assistance be not afforded, the health will assuredly suffer. Numerous examples of this kind are met with every day ; and, when treating them, we should always be careful to aid nature as far as possible by an appropriate diet and regimen, and not trust to medi- cine alone for rectifying the consequences of the patient's misconduct. In the great majority of cases the action of the bowels may be restored with little or no aid from me- CONCLUDING REMARKS. 275 dicine, provided a suitable regimen be observed, and the result be awaited with patience and prudent forbearance. I have already seen many examples of this fact in persons who had been accustomed for years to the use of purgatives, and believed they could not exist without them. It is true that some inconvenience was experienced at firsthand that some caution was required in determining how far to trust to the efforts of Nature. But in no instance did any bad consequences result even from considerable delay, when precautionary means were used to prevent it. In this, as in other instances, we ought never to lose sight of the great truth, that, if the bowels were originally constituted by the Creator with power to act sufficiently on the application of their own stimulus, food, there must necessarily be a wide departure from His laws in some part of our conduct to cause the loss of that power ; and, therefore, whenever we find the bowels unable to act without medicine, our first business ought to be to discover and rectify the error into which we have fallen—and recourse should be had to medi- cine only in so far as it shall be necessary to remedy the consequences which the transgression has brought upon us. As the sole object of the present volume is to make the reader acquainted with the natural laws of the animal eco- nomy, and with the means by which aberrations from them may be prevented and health preserved, I shall not enter at all upon the discussion either of the morbid conditions of the bowels or of the remedies by which these may be cured —and, consequently, shall say nothing farther of the use of purgative or other medicines. The consideration of these matters is not only foreign to the subject, but would require an extent of detail much beyond my present limits. Perhaps some persons may think that, before concluding, I ought to apologize for having introduced to the notice of the general reader such topics as those discussed in this and some of the former chapters. In doing so, I have been actuated by a deep sense of the misery arising from the pre- vailing ignorance on topics which, although in themselves as interesting and important as any to which the human mind can,' ie directed, have, nevertheless, been passed over in sih nee, partly from not the least suspicion being generally enter ain ed of their real bearing on our health and happi- ness, an 1 partly also from false notions of delicacy divert- ing al te ntion from their calm and deliberate examination. 276 CONCLUDING REMARKS. In endeavouring, therefore, to unfold what I conceive to be useful truths, in the language of reason, I confess that I feel no apprehension that any well-constituted mind will receive contamination from the perusal of what is contained in these pages. 277 INDEX. Abercrombie, Dr., quoted on intemperate eating, 18L Absorbents of the bowels, 137. Absorption most active before breakfast, 158. Rapid absorp- tion of liquids from the stomach, 50, 78.105, 121,159. Acids, in what cases they promote digestion, 96. Acidity of stomach, 246. Ages, different, require different kinds of food, 187,214,234. Albumen, composition of, 221. Albuminous aliments, 227. Aliments. See Food. Americans intemperate and rapid eaters, 179, 201. Animal food more digestible and nutritious than vegetable, 106,120, 217. Different kinds of, 222. Composition of, 221. Cause of its greater digestibility, 122. Also more stimula- ting, ib. Why apparently more binding, 152. Improper for infants, 236. Anxiety impedes digestion, 205. Appetite, its necessity as a warning that nutriment is re- quired, 31. Susceptible of being trained, 46. Not to be relied on when morbid, 47. A guide to quantity, 182. See Hunger. Thirst. Arrow-root, 111, 120. Barras quoted on the sensibility of the stomach, S3. Bathing improper immediately after meals, 202. Beaumont Dr., his view of the exciting cause of hunger, 36. Quoted on mastication, 60. His observations on the stomach of a patient named St. Martin, quoted, 74, 78, 84, 97,101,112, 116 et sea 17"7, 181, 197. Makes little pretension to the ho- nour of discovery, 99, 126. Summary of inferences drawn from his experiments, 126. Quoted on the quantity of food proper to be eaten, 176,181. On digestion, 197. Bile secreted by the liver, 145. Account of it, 146. Not found in the stomach during health, 147. Its presence there facilitates the digestion of fat and oily food, 248. Bilious temperament, 212. - Birds, gizzards of granivorous, 58,72. •) Blaine quoted on hunger, 38. Blood^irculated in the stomach increased by its action, 77, 197 Breathing necessary for the conversion of chyle into blood, 141. Fulness of blood, 189. Bloodletting improper im- mediately after meals, 202. 24 278 INDEX. Bloodvessels of the stomach, 76. Boarding-schools, time for breakfast and dinner in, 157, 160. Insufficient food often given there, 196. Bowels described, 131. Their different coats—the peri- toneal, 132 ; muscular, 134; and mucous, 135. Action of purgatives on the, 134, 136 Contain air, 135. Their sym- pathy with the skin, 136. Excretion and absorption of the, ib. Conditions essential to their perfect action, 142. Their ver- micular or peristaltic motion, 134, 150. Their nerves, 142. Why most open when vegetable food is used, 152. Regulation of, 264. Do not naturally require the aid of laxatives, 187. Their uses, 264 ; as an outlet of waste matter, 265. Their action bears a relation to the kind of food, ib. Causes of their inactivity considered,268. Natural ai3s to their action, 134, 269. General neglect of these, 271. Bad health thence aris- ing, 272. Their regularity important, 273. Bowel-complaint frequently produced by chill of the skin, 136, 264. Brachet, his experiments showing that hunger is an affec- tion of the brain, 33. Quoted'on hunger, 37. Brain, the seat of the sensations of hunger and thirst, 32. Should not be overtasked in childhood, 237. Influence of its state upon digestion, 203, 238, el seq. Brains as food, 228. Breakfast, proper time for, 157. Labour before it improper without refreshment, 160. Diseases, easily caught before breakfast, 158. Reading newspapers during it improper, 59. Brigham, Dr., referred to, 238. Caldwell, Dr., quotedon intemperate eatingin America, 179, 201,206. On the influence of the state of the brain as a source of indigestion, 217. Carnivorous animals have small organs of digestion, 70,121, 125. Their existence necessary, 91. Their gastric juice, 94. Carswell, Prof., on softening and erosion of the dead sto- mach by the gastric juice,, 92, note Cassius, his leanness as described by Shakspeare, 205. Cheerfulness promotes digestion, 111,217. Chewing, 51. See Mastication. Chicken, 224. Children, great importance of regulating their diet properly, 165, 185. Prevalent error of over-feeding them. 184, 236. Suffer also from deficiency of food, 236. Animal diet not to be given them too early, 235. Impropriety of tasking and con- fining them too much at school, 237. Dull children often be- come talented men, ib. Cholera, loss of the fluid parts of the body in, 50, 137. Chyle, 66. Its composition the same, from whatever food derived, 63. Chyliflcation described, 130. This subject ra- ther obscure, ib. Chyle converted into blood in the lungs, 140. INDEX. 27* Chyme, 65,127. Clark, Sir James, on the great importance of the proper re- gulation of diet in youth, 236,242. Clarke, Adam, a dunce at school, 238. Climate ought to modify food, 124. Appetite in warm cli- mates, 43. Coagulation of milk and albumen by gastric juice, 93,104. Ccecum, 149. Coffee after dinner, 171. Colon described, 149. Condiments, 128. i Constitution. See Temperament. Consumption, pulmonary, how productive of leanness of the body, 141. Often the result of mismanagement of diet in childhood, 237, 242. Cookery, influence of, 220. , Cornaro, 181. Costiveness, causes of, 134, 189,267. Howremoveable,272. Crime from deficiency of food, 195. Cumberland, Richard, beneficial effects of his temperate habits, 230. Deffand, Madame de, quoted, 37. Deglutition of food, 61. Diet, adaptation of, to individuals, 231, 244. To circum- stances, 183. Errors in, in maturity, 190. Defective, of la- bouring classes, 194. Effects of, on crime, 195. See Food. Meals. Dietetics, principles of, viewed in relation to the laws of digestion, 153. Digestion, vigorous and rapid in proportion to the quantity of nourishment required by the body, 39. Organs of, described, 63, et seq. Its wonderful power of reducing the most opposite varieties of food to the same substance, ib. Nervous energy essential to, 81, 228. Different theories of, 99. Is a chemico- vital process, 101. Conditions requisite for it—1. A suffi- ciency of gastric juice, ib. 2. A temperature of 98° or 100°, 106: and 3. Gentle agitation of the contents of the stomach, 107. Aided by laughter and cheerfulness, 111. Ill performed when previous meal remains in stomach, 113. Comparative digestibility of different kinds of food, 116. Time required for digestion of the same article different in different states of the body, 119. Animal food more digestible than vegetable, 106, 120,217,219 ; and why, 121. A proper selection of food not the only requisite of good digestion, 154. Is the temperature of the stomach raised during digestion? 125. Vegetable food partly digested in the intestines, 150. Vigorous in youth, 211. Retarded by bodily or mental exertion immediately before or after eating, 203, et seq. Intellectual vivacity diminished 280 INDEX. while digestion is going on, 201. Influence of the mind upon digestion, 204, et seq. Dinner, proper time for, 162,174. Early dinner-hours best, 162. Fashionable late dinner-hours, 168. Relaxation neces- sary after dinner, 169, 202. Time for dinner ought to vary with circumstances, 168. Drams at, 263. Drink necessary to supply the waste of the liquid portions of the body. 49. Bad effects when withheld, ib. Absorbed directly from the stomach into the system, 50,78,105,121, 158. Temperature of drinks considered, 252-6. Water as a drink, 254, 257. Wine and other fermented liquors, 257. Spirits hurtful, 258. Sudden changes of its temperature hurtful to the teeth, 55. See Liquid. Thirst. Dunglison's Elements of Hygiene quoted and recommended, 251,255. Duodenum, 65,143. Dyspepsia sometimes an advantage, 192. Prevalent in United States, and why, 201, 206. Vegetables and soup often bad in, 245. Eating ought not to be too rapid, 59,108. Times of, 153. Eating too much, a prolific source of disease, 40,179. Con ditions to be observed before and after eating, 197. See Food. Meals. Eggs, 228. Epiglottis, 62. Excrement, 130,148. Excretion of waste matter into the bowels, 136. Exercise renders appetite keen, 37, 38, et seq. Prevents costiveness, 180, 252,271. Improper immediately before and after meals, 222. Farinaceous food, 106,120, 229, 247. Fermentation and digestion different processes, 100. Fermented liquors, 257. Fever, loss of appetite during it a wise arrangement, 46, 98. Fibrin, composition of, 221. Fibrinous aliments, 222. Fish, 229. Fluids. See Drink. Liquid. Thirst. Follicles of the stomach, 76. Food necessary to supply waste of the substance of living beings, 27. Requisite quantity varies according to circum- stances, 28, et seq. Warning given by hunger when food is required, 31, 32, 37, 175. Most necessary durin<; growth, 39, 241; and when the life is active, 40, et seq. Error of eating too much, 41, et seq., 175. Thirst varies in intensity according to the kind of food, 49. Mastication, 51, insalivation, 58, and deglutition of food, 61. Its quality modifies the amount of saliva secreted, 60. The most opposite kinds of food reduced 281 by digestion to the same substance, 63. Different stages through which food passes between its reception into the sto- mach and its assimilation, 65. Size of the stomach varies according to its quality, 70. Advantages of our want of con- sciousness of its presence in the stomach, 82. Sudden and extreme changes of diet injurious, and why, 95. Ought not to be rapidly swallowed, 59,109. Thoroughly mixed with the gastric juice in the stomach, 110. Concentrated food, why digested with difficulty, 111, 123, 249. Ought not to be taken till previous meal is digested, 113. Comparative digestibility of different kinds of, 116. Animal food more digestible and nutritious than vegetable, 106, 120, 217, 220, 248 ; and why, 122. Farinaceous food, 106,120, 229. Soup, 105, 111, 121, 225. Changes of food in the bowels, 130, 217. Injection of food into the bowels, 138. Times of eating, 154. Quantity to be eaten, 176. Bad effects of eating too much, 179. Are mixtures of food hurtful ? 181. Food of children—See Chil- dren. Food of the poor too scanty, 193 ; consequences of, 195. Proper food of man, 197. Variety of human food, 208. Dif- ferent kinds of animal food, 222. Different kinds of food suitable in different climates, 124 ; for different constitutions, 209, 232 ; and at different ages, 214, 234. French meals, 158. See Meals. Eating. Gall-bladder, 146. Gall-stones, ib. Game, 223. , , . . , . Gastric juice, 65, 83. Secreted only when there is food in the stomach, 88. Its chemical composition, 90 Acts only upon dead inorganic substances, 91. Its power of coagulating milk and albumen, 93, 104. Its antiseptic quality, 93, 105. Adapted in different animals to the nature of the food, 94. Modified in the same individual according to the wants of the system, 96. On which of its elements does its solvent power depend? ib. The amount secreted always in proportion to the quantity of aliment required by the body, 97, 177. Its se- cretion retarded by disagreeable mental emotions and fever- ishness,97,197. Indispensable to digestion, 101. Thoroughly mixed with the food in the stomach, 110. Adaptation of food to its qualities in different individuals, 122. Gelatine, composition of, 121. Nutritive power of soup made from, 225 Gelatinous aliments, 224. Gizzard of granivoious birds, 58, 72. Grief enfeebles digestion, 111,205 . Growth, periods of, require.an increased supply of food in vegetables, 30 ; and animals, 30, 39,178. Diet during, 241. Head. Sir Francis, quoted on the quantities of cold water drunk at the brunnens of Nassau, 160 ; and on the prejudicial effects of intemperate eating, 178,189. 24* 282 INDEX. Heidler, case quoted from, 183. Herbivorous animals have large organs of digestion, 70,1"1, 125. Their gastric juice, 74. The digestion of their food partly effected in the intestines, 150. Hippocrates, his theory of digestion, 100. Horse, should not have diet suddenly changed, 95. Diges- tion of the, 150. Is not fed immediately before or after a jour- ney, 201. May sometimes drink a little though perspiring, 256. Hufeland quoted on the beneficial influence of laughter in aiding digestion, 112. Hunger, necessity of the sense of, as a warning that food is required, 31,175. An affection of the brain, 32. Allayed by narcotics, 33, 34. Influenced by mental emotions, 35 By what condition of the stomach is it excited? 36. Felt keenly when the body is in need of repair, 37, et seq. Sharpened by muscular exercise, 37, 38. Its absence during fever a wise arrangement, 45. Susceptible of being trained, 46. Error of confounding it with taste, ib. Morbid cravings of hunger when food is not required, 47. Instances of extraordinary voracity, 48. Periodicity of, 154. Does not return till stomach has been for some time empty, 155. Hydra, stomach of the, 67. Ices and ice-creams hurtful after a meal, 254. Ice useful in warm weather when used with caution, ib. Examples in Italy and Virginia, 255. Ileum, 148. Indigestion, why prevalent among sedentary persons, 44, 232. Injures the teeth, 56. Often beneficial in warding off more serious diseases, 193. Caused by grief, anxiety, and over-study, 111,205. Infants, food proper for, as indicated by the state of theit teeth, 55. Diet of, 185, 234. Prevalent errors in the treat- ment of, 236. See Children. Infection, why most easily caught before breakfast, 158. Injection of food into the bowels, 138. Insalivation of food, 58. Intemperate eating a prevalent cause of disease, 178. Dr. Caldwell on, 179. Evils of, 190. Drinking, 251. Intestines described, 131. Changes on animal and vegeta- ble food produced in, 217. See Bowels. Jejunum, 148. Jelly, 111. Kitchiner, Dr., quoted on digestion, 107,156. Lacteals, 66,137. La Trappe, diet of the monks of, 156. Lamb, 224. Laughter aids digestion, 112. Laxatives, 134,188,249. INDEX. 283 Lent, rapid recovery of the sick in Catholic countries during it, 179. Liquid food, 78,105, 121, 217, 233. Too cold or hot inju- rious, 236,239. Different kinds in use, 232. Literary men, indigestion of, 168, 203. Liver, its function, 145. Londe, Dr., quoted on the digestion of vegetables, 151. Ex- periments on intestinal digestion, 217. Luncheon, 164. Lungs, how wasting of the body is produced by their disease, 141. See Consumption. Lymphatics, 138. Lymphatic temperament, 211. Mastioation, process of, described, 51. Its apparatus va- rious in different animals according to the nature of their food, 58. Bad effects when mastication is incomplete, 59. Pur- pose of, 60. Maturity, errors of diet in, 190. Meals at what times and after what intervals they ought to be taken, 155. Relaxation necessary after them, 169. Prin- ciples on which their times and number ought to be fixed, 172. Conduct proper before and after meals, 197. Inaptitude for bodily and mental exertion after them, 198. Rest and tran- quillity then necessary, 199. Whether drink is proper during meals, 251. French meals, 171. See Food. Eating. Meconium, 188. Mesenteric glands, 140. Mesentery, 133. Mesocolon, 134. ... Milk, coagulated in the stomach by the gastric juice, 93,104. Digested with ease, 120. The natural food of infants, 186, 235 Miller, Captain of Glasgow Police, on starvation as a cause of crime, 195. . .. Milliners, an improvement in the management oi their es- tablishments suggested, 184. Mind, its influence on appetite for food, 35. Deteriorated by defective nutrition, 195. Ought to rest during digestion, 199, 202. Its influence on digestion, 205, et seq. Mirth promotes digestion, 111, 203,205. Mixtures of food, whether prejudicial, 181. Monks of La Trappe, diet of, 157. Montegre's opinion of the use of saliva, 61, 92. Morning, exposure before breakfast often dangerous, 158. Vigour of "the system then least, ib. Mortality of children, 185. Mortality greatest among the l'°Mothers generally ignorant of the rational mode of treating children, 186. 284 INDEX. Mucous or villous coat of the stomach, 75; and intestines, 136, 144. Muscular coat of the stomach, 73; and intestines, 134. Muscular exercise. See Exercise. Mutilation of animals, unsatisfactory nature of experiments so made, 80. Napoleon not a bright school-boy, 238. Narcotics allay hunger, 33, 34. Nerves of the stomach, 39, 78. Of the bowels, 142. Nervous energy essential to digestion, 81, 204. Tempera- ment, 212. Newton, Sir Isaac, a dull school-boy, 237. Nursing of children, 18C, et seq. Nutrition required to repair waste of substance in living beings, 28. See Food. GKsophagus, 61. Operatives ought not to resume work immediately after meals, 204. Opium allays hunger, 34. Overfeeding, evils of, 183,188. Oysters, 228. Pancreas, and pancreatic juice, 66,148. Parker on dyspepsia, 272. Paris, Dr., an opinion of his controverted, 124. Pastry not easily digestible, 248. Periodicity of appetite, 155. Peristaltic motion of the bowels, 134, 150, Peritoneum, 73, 132. Philip, Dr. Wilson, an opinion of his controverted, 112. Pneumogastric nerve, 79. Poor have larger stomachs than the rich, 70. Their food too scanty and innutritious, 193. Their minds thereby de- teriorated, 195. Precocity of talent little to, be desired, 238. Purgatives, their mode of action, 134,137. Not required by nature, 188. Putrefaction, digestion different from, 100. Pylorus, 70. Allows only digested food to issue from the stomach, 115. Quantity of food proper to be eaten, 176. Errors in, ib. Dr. Beaumont on excess in, 170-7. Cornaro and Cheyne on. 181. Rapid eating improper, 59,109, 201. Reading during meals improper, 59. Rectum, 149. Repose before and after meals, 199. Ob- served in animals;201. Evils of neglecting, ib. Respiration, use of, 66. Digestion aided by, 111, 141. Ne- cessary for the conversion of chyle into blood, 141. Rice, 106,120,265 INDEX. 285 Roget, Dr., quoted on nutrition, 42; on varieties of food, 64. Rumination of animals, 53, 58. Stomach of ruminants described, 71. ' Sago, 106, 120. Saliva, secretion and purpose of, 58. Its amount greatest when food spicy, 60. Different in quality from gastric juice, 92. Salt meat, how productive of thirst, 49. Sanguification, 66,140. Sanguine temperament, 212. Satiety, 176. Schools, children too much confined and tasked in, 237. See Boarding Schools. Scrofula frequently the result of a penurious diet, 196,236; also of too exciting food, 242. Sedentary habits, how productive of indigestion, 41; and costiveness, 135,150, 272. Less food required by sedentary than by active persons, 182. Sheridan a dunce at school, 238. Siesta, 202. Skin, its sympathy with the bowels, 136,264. Smith, Dr. Southwood, quoted, 82, 194. Soldiers, private, why inferior in strength and health to offi- cers, 194. Ought not to eat immediately after a march, 200. Soup, digestion of, 105, 111, 121. Gelatine soups, 226. Spirits, their indiscriminate use hurtful, 258. Effects of, on stomach, 260. Spittle, 58. See Saliva. Spleen, 144. St. Martin, Alexis, remarkable case of, 84. Suggestion as to farther observations on, 88, note. See Beaumont. Stays injure the action of the bowels, 134,150. Starvation and crime, 195. Stomach, peculiar to animals, 28. By what state of it is hunger excited 1 36. Its sympathy with the rest of the body, 36. et seq. Described, 67, et seq. Stomach in the lowest class of animals, ib. In man, 69. Various in size according to quantity and quality of food, 70. Stomach of ruminating ani- mals described, 71. Coats of the stomach—external, 73; muscular, ib. ; and mucous or villous, 75. Its muscular action, 74. Its bloodvessels and follicles, 76. Its sanguineous cir- culation increased during digestion, 78. Its power of absorb- ing fluids, 50, 78, 105, 121, 159. Its nerves, 78. Contracts when each morsel is introduced, 109. Its motion during di- gestion, 111. Is its temperature then increased? 125. Con- tains no bile in the healthy state, 147. Sensibility of the, a sign of disease, 82. Numerous diseases unjustly laid to its charge, 189. Effects of spirits on, 260. Supper, in what cases proper, 171. 286 INDEX. Swallowing, process of, 61. Sympathetic nerve, 82. - Tartar on the teeth, 55. Tasso, his genius precocious, 238. Taste, error of confounding it with appetite, 46. Its gratifi- cation proper, 59. Tea, 171,252,255. Teeth described, 51,53. Modified in different animals to suit their habits of life, 53. Milk-teeth, 54. Changes of the condition of the teeth indicate the propriety of certain kinds of diet, 55, 234. Necessity of keeping them clean, 55. Im- paired by indigestion, 56. Sudden changes of temperature hurtful to them, 57. Temperaments, or constitution, different kinds of, consider- ed in relation to food, 208. May be greatly modified by regi- men, 244. Temperance in eating may be carried too far, 196. Tem- perance Societies, 260. Temperature necessary for digestion, 106. Whether that of the stomach is thereby increased, 125. That of drinks con- sidered, 252. Thinking, intense, impedes digestion, 203. Thirst necessary as a warning when drink is required by the system, 31, 50, 250. Nature of, 33, 48. Greatest when body in need of liquid nourishment, 49. Varies in intensity according to nature of the food, ib. Consequences of its cra- ving not being gratified, ib. See Drink. Thoracic duct, 66, 140. Time in which the digestion of an article is effected varies with circumstances, 119, 128. Times of eating, 153,154. Tobacco allays hunger. 34. Tooth-powders, 56. Training, effects of, on eating, 156, 244. Travelling before breakfast frequently improper, 160. Diet in travelling, 175. Trituration, digestion not effected by, 100. United States, dyspepsia prevalent in, 201. Veal, 224. Vegetables, continual waste of their substance, 26. How repaired, 27. Quantity of nourishment requisite for them varies with circumstances, 29 Principle of forcing their growth, ib. Vegetable food less digestible than animal, 106, 120; and why, 122. Also less nutritious, 121. Its digestion effected to some extent in the intestines, 151. Properties of, 230 • acidity from, 247. Why more laxative than animal food, 152,' 248. Venison, 248. Vermicular motion of the bowels, 134,150,271. INDEX. 287 Villous or mucous coat of the stomach, 75, and bowels, 135. Vomiting, inverted action of the gullet and bowels in, 63, 134. Vomiting of bile, 147. , Voracity, remarkable instances of, 48. Waste universally the attendant of action, 25. Food the means of repairing it in living beings, 27. See Food. Waste matter excreted into the bowels, 136, 248. Water safe as a drink, 257. Cold spring water dangerous when person overheated, 255. Water-brash, 76. Wine, how productive of thirst, 49. Circumstances in which its use is proper and improper, 258. Preferable to spirits, 259. Worms in the bowels, 137. Youth, appetite keen and digestion vigorous in, 39. Im- portance of properly regulating the times of eating in youth, 166, 187. Parents blameable for errors in, 186. Diet in youth, 238,241. Errors in diet of the young, 242. Supper frequent- ly necessary, 172. Period of transition from youth to man- hood a critical season, 185. Diseases of the stomach and bowels why then common, 272. See Children. Infancy. Mothers. THE END ■o ■■■"• <. »■.- V •' ■■'i?.:\:. ;■■;'•' ."_ «•■■- ■ • ..'.♦• » ••. :*;» -" " -*T'*«'*••'.-■' *. ■ * •'■'■!•;•' .- v "■-. ."■ • Stfcv*"- ■'■'ziyZi'-:.''■ :;-•;'v,-v--., ■,.'-. :.'■'.■ ■/-. t-.f • •■•...■ :.>>-r-r'-:f:v--:' ;. *. '.'..• ;■;>. ;:%- '.. .'ww'-