THE X - . v\- - ' PHILOSOPHY OF UTERINE DISEASE, WITH THE TREATMENT APPLICABLE TO DISPLACEMENTS AND FLEXURES. BY THOMAS ADDIS EMMET, M. D., STJROEON TO THE WOMAN’S HOSPITAL OP THE STATE OP NEW YORK. [REPRINTED FROM THE NEW TORE MEDICAL JOURNAL. JULY, 1874 ] NEW YORK: I). APPLETON AND COM P A N Y . 549 & 551 BROADWAY. 1874. TWELVE YEARS OF THE WORLD’S HISTORY! APPLETON S’ AMERICAN ANNUAL CYCLOPAEDIA FOR 1872. 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THE PHILOSOPHY OF UTERINE DISEASE, WITH THE TREATMENT APPLICABLE TO DIS- PLACEMENTS AND FLEXURES.1 It would be difficult to present a subject on which a greater diversity of opinion exists in the profession than the one I now have the honor of offering for your consideration. This difference is not only as to cause and effect, but to as great an extent in relation to the proper means of treatment. Indeed, at first sight, this great difference is incomprehensible, and it seems impossible to reconcile the extreme views held by men of honest purpose and equally based on personal observa- tion. But experience has long since taught me that a medi- um course is the most successful one, as from this stand-point we can utilize and better appreciate the views based on the practice of either extreme. In years past I have honestly overcome all obstructions, and by the aid of the knife I have opened up the uterine canal to such an extent that it was im- possible for any mechanical obstacle to exist; and I did not cure my patients. In turn I have devoted no little mechanical skill to overcome every displacement, and have succeeded beyond my expectations; yet the results were not satisfactory. At length I became confident that local congestion and inflam- mation were the causes of the evil, producing hypertrophy, liypersesthesia, versions and flexures. I directed my treatment 1 Bead before the Medical Library and Journal Association of New York, June 5, 1874. 4 THE PHILOSOPHY OF UTERINE DISEASE. now exclusively to relieving the congestion, as I will describe hereafter. My results were better, for I found that as I di- minished the congestion, the hyperaesthesia disappeared, the flexures lessened in degree, and there was, with less hyper- trophy, a great improvement in the versions; but my patients frequently relapsed, and the results were not such as I had an- ticipated. I ultimately recognized the fact that there was a stage in the treatment of almost every case when mechanical support was indispensable as an adjunct, and under certain circumstances the use of the knife could not be ignored. The fact also presented itself to me that in a large number of cases the local condition was secondary to that of the general system, and in no case could we conscientiously overlook the connec- tion. I became convinced that, as a rule, the local difficulty in the beginning was the effect, but a point was reached ulti- mately when the uterine condition became the most promi- nent, and exercised a direct influence in reducing still further the tone of the general system. In addition, experience taught that we cannot restore the female to health by local treat- ment alone, nor by devoting our attention exclusively to the general condition can we relieve the local one. I regard some degree of anteversion as a normal position of the uterus, while retroversion is always incident to, and a flexure is an exaggera- tion due to, causes to be considered hereafter. Any conceivable amount of deviation from a normal stand- ard may and does frequently exist without discomfort, so long as the circulation remains unobstructed and the proper func- tions are performed. Deviations may result from congenital causes, or from accident, and a degree of tolerance may be- come established which ultimately seems to be a normal con- dition for the individual. Yet there is in each case a limit to the immunity, as sooner or later Mature exacts the penalty. A retroversion may exist for years "without producing incon- venience, but from some accidental cause the general health may become impaired ; the vaginal walls will gradually lose their integrity, a miscarriage, or some other cause, will pro- duce an undue congestion, with enlargement of the uterus, and we have at length the most urgent symptoms presenting themselves for relief. There is less immunity from flexures of THE PHILOSOPHY OF UTERINE DISEASE. 5 the body of the uterus, yet a moderate amount of disease may he borne so long as the general health remains good. A flex- ure of the cervix below the vaginal junction, at a right angle even to the body, or a partially constricted os, may produce but little discomfort for an indefinite time, beyond a slight dys- menorrhoea in the unmarried female; but in the wife, if the condition has produced sterility, we are at length forced by a train of nervous symptoms to recognize a local cause of irri- tation. In other words, anteversion may exist without caus- ing irritation of the bladder, retroversion without symptoms of prolapse or obstruction to the rectum, and flexure without dysmenorrhcea, so long as the nutritive functions maintain their integrity. Impaired nutrition, as the cause and not the effect, depre- ciates the nervous force, and without this needed stimulus functional derangement naturally follows, a loss of balance re- sults, and we have congestion or the opposite condition. Con- gestion produces enlargement of the tissues, and it may remain passive or result in inflammation, while a want of nutrition causes atrophy. Congestion is always the result of some local irritation, a condition which is but temporary in duration if the reparative powers are in a state of integrity. Congestion, however, does not imply inflammation, although the latter cannot have a beginning without it. If the congestion reaches a degree sufficient to establish inflammation, we have at once instituted a distinct train of symptoms which is acci- dental and secondary to the primary condition. The terms congestion and inflammation are synonymous with many in application to uterine disease, and it leads to confusion. In- flammation cannot exist without molecular death, and its products are easily recognized until the injury has been re- paired. We may look in vain, post mortem, for any evidence of a previously-existing endometritis, so called, or ulceration of the cervix, as it is termed. We find the tissues blanched, the blood from the capillaries having passed into the larger vessels as the heart failed in keeping up the supply, but there is neither loss of tissue on the surface of the mucous membrane beyond the epithelium, if so much, nor are products of in- flammation to be found in the tissues of the organ itself. In- 6 THE PHILOSOPHY CF UTERINE DISEASE. flammation can only exist in an acute form, although its products may remain for an indefinite period. Therefore the term chronic inflammation is a misnomer. From congestion and increased weight the uterus will nat- urally settle into the pelvis, and a version mechanically results toward the heavier side. The neck of the uterus soon becomes, as it were, a fixed point, and can move but forward in the axis of the vagina, while the body above becomes bent on itself in the opposite direction. Hence, a flexure of the body, a chor- dee, as it were, to be augmented by any increase or obstruc- tion to the circulation. Violence or an accidental cause may produce partial retroversion, and, if the fundus advances into the hollow of the sacrum beyond a certain point, we have at once two forces operating, in opposite directions, to produce a retroflexion. The cervix becomes pressed upward against the anterior wall of the vagina, which can only yield to a certain degree, and, with the weight and downward pressure in the opposite direction, the body of the uterus is gradually bent upon itself. We have two causes of flexure which may be termed congenital, or at least having an origin previous to puberty. As the uterus becomes developed, the growth of the cervix is, in length, out of proportion to the body. Grad- ually, from a want of room, the cervix slides along the pos- terior wall, in the direction of the least resistance, until it presents in the axis of the vagina, causing a sharp flexure just at the vaginal junction. In a narrow vagina, with a de- ficiency or absence of the posterior cul-de-sac, a degree of re- troversion must exist. At puberty, with increased weight of the uterus and from other causes, the fundus gradually settles into the hollow of the sacrum, and we have a flexure pro- duced in the same manner as I have shown to follow this dis- placement when resulting from accident. Congestion of the mucous follicles, limited to the cervix or extending through the uterine canal, with increased secre- tion and some enlargement of the organ, is the most common form of uterine disease. In my experience, some degree of flexure of the body, with an increase of anteversion, lias been more frequently met with than in the displacement backward. Partial obstruction of the uterine canal, at a given point above 7 THE PHILOSOPHY OE UTERINE DISEASE. the vaginal juncture, is caused by flexure, and is increased by congestion, with passive oedema of the mucous membrane and possibly of the submucous tissues. A resort to surgical means for the relief of this condition has been a favorite pro- cedure with many in the profession. For years I have not divided the cervix laterally except for the removal of fibroids. At an early date in my experience, I satisfied myself that a flexure of the body could not be relieved by a lateral division, even if extended to the vaginal junction, and that the prac- tice was based on unscientific principles. I have never seen a case permanently benefited by the operation, except in rare instances, where pregnancy fortunately took place during a slight remission of symptoms, due to the revulsive action at- tending the process of reparation. I can, moreover, state that I have never known the malpractice of any other surgical procedure followed at times by such evil consequences. When practised by skillful hands, under proper surroundings, and with the requisite after-treatment, the operation is attended with comparatively little risk, but without benefit. It has been regarded by the profession at large as a simple operation ; and it is certainly one in execution, but it requires no little ex- perience to decide when it can be practised with safety, even when it is advisable. I believe that there are but few of us who have not in years past seen the most deplorable results fol- lowing the indiscriminate practice of this operation, through reckless inexperience and neglect afterward. November 28, 1862, I operated on a patient, who had re- ceived, in labor, a double lateral laceration of the cervix to the vaginal junction, by denuding and bringing together with sil- ver sutures the anterior and posterior flaps. It was a case in my private hospital. I was assisted by Dr. G. S. Winston, then my assistant, and I believe Dr. T. G. Thomas was also present at the operation. This lady suffered from hypertrophy of the uterus, with an intractable erosion covering a cervix apparently some two inches in diameter. The erosion by great care had been several times healed, but its recurrence took place as soon as she began again to exercise. She had been some time un- der treatment before I appreciated the laceration, as the tissues had undergone fatty degeneration, and were so softened and 8 THE PHILOSOPHY OF UTERINE DISEASE. flattened out as to give no evidence, on inspection, of the real condition. My attention was first attracted to the width of the cervix in comparison with the body, during an examina- tion with the finger, as the patient was lying on the hack. The relative size of the cervix to the body of the uterus was as the top of a half-grown mushroom would be to its stalk. By seizing the anterior and posterior portions of the cervix with a tenaculum in each hand, I found that, when the flaps were brought into apposition, the inverted portion rolled in- ward to the canal, and the cervix was in fact then but little larger than natural. The remedy at once suggested itself to me, and I performed the operation to which I have referred, the effect being that the hypertrophy rapidly diminished, with no recurrence of the erosion afterward. It was evident that the hypertrophy and erosion had been due to the rolling out of the tissues, as the flaps were forced apart on standing, by the posterior one catching on the recto-vaginal septum, while the anterior flap was crowded forward in the axis of the canal, in the direction presenting the least resistance. This case.was one of great importance to me, for it has been my practice from that time to close all lateral lacerations which have passed under my observation as a result of labor. It led me also to appreciate exactly the same condition as a result of lateral division of the cervix in all cases where the operation had been thoroughly done; and I have since in every in- stance endeavored to correct the damage by reuniting the flaps before resorting to any other treatment. I know of no one previous to this time who had recognized this chronic condition as a cause of hypertrophy and extensive erosion, when resulting from childbirth, or as a consequence of lateral division of the cervix ; and I believe the above operation to have been the first practised for its reparation. In a paper entitled “ Surgery of the Cervix,” published in the American Journal of Obstetrics, and read before the Medical Society of the County of Hew York, February 8, 1869, I have pre- sented my views at greater length in reference to this condi- tion and operation. When the flexure occurs at or below the vaginal junction, it is seldom in the unmarried that we are called upon for the THE PHILOSOPHY OF HTEEINE DISEASE. 9 relief of any serious uterine disturbance until later in life. Dysmenorrhoea, it is true, always exists in the beginning of the flow, but is relieved as soon as it has become established, while the contrary is the case when the flexure is in the body of the uterus. In the latter condition the dysmenorrhoea does not begin until menstruation has already made its appearance, it then increases in degree, and continues until the flow ceases. In the first instance, the long and narrow cervix becomes thick- er, shorter, and straighter, in consequence of the menstrual con- gestion, so that the mechanical obstruction is removed for the time. With flexure of the uterine body, in either anteversion or retroversion, the obstruction becomes exaggerated on in- creased congestion. This is due to the fact that the disease is confined chiefly to one side of the organ, while the circula- tion is comparatively unobstructed on the opposite side. For the relief of the flexure at the vaginal junction, I al- ways divide, with scissors, the posterior lip backward in the median line. This operation is attended with but little risk, if the case is properly cared for, from the fact that the organ is otherwise in a comparatively healthy condition ; unless the history of the case points to the existence of a previous attack of cellulitis, resulting from some accidental cause, there will be but little danger of this complication from the operation. Quite the contrary will be the case when the body has been involved in either anteflexion or retroflexion of long standing, for a certain amount of perimetritis is almost certain to have existed at some previous date, leaving a condition afterward requiring but a slight provocation to reestablish the inflam- mation in a more serious form. The ultimate result of the operation is to bring the neck to a natural length, for, by a division of the circular fibres, the longitudinal ones gradually retract, and the canal becomes straight; were other advan- tages equal, the backward operation is preferable to the lateral one, as the cervix is divided only on one side, and the risk from haemorrhage is less, as the circular artery can be easily avoided. Moreover, there will be no gaping or rolling out of the edges, after they have healed, as the flaps are kept suffi- ciently in contact by the lateral walls of the vagina. Al- though there may be no bleeding at the time of the opera- 10 TIIE PHILOSOPHY OF UTERINE DISEASE. tion, the use of a tampon for some ten days is a necessary precaution to guard against subsequent haemorrhage. The incision must be kept open by gently drawing the point of a sound through the angle of the wound, and the edges apart by daily dressings of cotton pledgets saturated with glycerine. To guard against inflammation, it is indispensable that the patient should be kept in bed, and protected from cold, until the parts have healed. The object of the operation is to re- move a very common cause of sterility, and one liable to re- sult in retroversion, from sexual intercourse, with prolapse afterward, so soon as the body becomes forced over in line with the axis of the vagina. In the unmarried the dysmen- orrhoea is relieved by the operation, the tendency to retrover- sion obviated by shortening the neck, and an exciting cause of future disease removed by allowing of a free escape of the secretions from the canal. When a flexure of the body has long existed, the tissues, at the point of greatest constriction, gradually undergo fatty de- generation from pressure, and absorption takes place, causing a permanent deformity, as after caries of the spine. When a point has been reached, after careful treatment of such a case, at which all tenderness on pressure has been removed, it is often judicious to divide the cervix backward, and to incise forward the seat of flexure above, sufficiently to open the canal. This will facilitate the application of any after-treatment which may be found necessary to the canal above, and guard against a relapse from any mechanical obstruction afterward. But, if done too soon, without the proper preparation and the requisite subsequent care, all previous gain will be lost by pel- vic cellulitis, and even general peritonitis may result. The patient’s life may be saved for the time, but there is seldom vitality enough remaining even to regain the condition exist- ing previous to the operation. During the time I held the position of surgeon-in-cliief to the Woman’s Hospital, from September 1, 1862, to May 1, 1872, there were 1,842 patients treated under my charge. This operation was performed sixty times in the institution, as will be seen by the following statement taken from the records and furnished me by Dr. William II. Baker, the house-surgeon. THE PHILOSOPHY OF UTERINE DISEASE. 11 From September 1, 1862, to the close of the year, eight opera- tions; 1863, nine; 1864, six; 1865, four; 1866, three; 1867, three; 1868, five; 1869, six; 1870, thirteen; 1871, one; 1872, to May 1st, two. During the year 1870 four lateral operations were performed for the removal of fibroids, making a total of fifty-six operations for flexure of the cervix. The operations were all, I believe, performed by myself, except during the year 1870, when my assistants, Dr. J. G. Perry and Dr. Bache Em- met, operated six times—the former five times, the latter once. Three cases of serious cellulitis followed these operations, but from which complete recovery took place ; one death occurred from general peritonitis, coming on after the patient was well enough to be up, and it could be attributable alone to her own imprudence. This patient was sent to the hospital by Dr. Baur, of Brooklyn, but now of St. Louis; after permission had been refused, she took a cold bath with her windows open, and was seized with a violent chill before she had completed her toilet; it was followed immediately by a most violent attack of peritonitis, and death resulted in a few days. During the past thirteen years I have operated some forty- nine times in my private hospital, and have in the same pe- riod treated two thousand and thirty-six uterine patients, with one death and one serious case of cellulitis, terminating in pelvic abscess, from which recovery took place after an illness of two years. The cause of death was peritonitis, occur- ring in a case where I operated the day after her arrival from a long and fatiguing journey, to oblige her physician, who wished to return home without delay. I have since held myself culpable for the death of this patient, so far as to have deviated from my rule in never operating until a patient has been sufficiently long under observation for me to appreciate fully her condition and to prepare her properly for it. The pelvic abscess, following an attack of cellulitis, wras brought about by the patient’s imprudence in sitting up and exposing herself to cold in her night-dress, and bare feet. To the best of my recollection, I have performed this operation but twice outside of my private hospital, and in both instances the patients remained under the charge of their physician. One of these cases, on whom I operated for retroflexion, died 12 THE PHILOSOPHY OF UTERINE DISEASE. ultimately from the effects of a pelvic abscess. It occurred some years ago, before I had learned from experience that in cases of retroflexion a certain amount of cellular inflammation has previously existed, and that its products are seldom if ever absent so long as the organ remains in this position. The lady was a foreigner with whom I was unable to hold any per- sonal communication ; the operation was performed at a large hotel where she did not get the proper care, and I have no doubt she suffered from exposure. The number of cases treated in private practice has been given, that they may be added to those cared for at the hos- pital, from the fact that many of the patients were sent to the institution by me specially for the operation—as otherwise the proportion would be too large. The ratio to the whole number treated can be but an approximation, however, since I can give no estimate of the number seen by consultation in private practice, or with accuracy the number treated in the outdoor department of the institution; and yet many of the operations performed were on patients received from these sources, although the proportion of operations to the given number of uterine cases under treatment is larger than it would be in reality, could we arrive at the total number under observation, yet it is sufficiently small to show that this operation has never been with me the rule of treatment. We will now consider briefly the mechanical means to be resorted to for the relief of displacements. I am ignorant of any instrumental means, safe or reliable, for correcting the po- sition of an anteverted uterus. Great relief may sometimes be obtained, on increasing the degree of anteversion, by the use of a pessary with a long-enough curve in the posterior cul-de- sac to lift the neck of the organ from the floor of the pelvis. On thus slinging the organ, as it were, with the fundus resting against the pubis and the cervix elevated, the circulation will be improved, and the irritability of the bladder lessened. We gain time by this means, and enable the patient to take more exercise, since we break the force or jar which would be other- wise transmitted to the organ so long as the cervix rested on the floor of the pelvis. The various devices for forcing the uterus into an upright position to a point which the organ THE PHILOSOPHY OF UTERINE DISEASE. 13 likely never occupied even when in a healthy state, are faulty in theory and wrong in practice. If we can lift, by any appli- ance, the uterus to a point where the obstructed venous circu- lation can be relieved through the neighboring tissues, which have been put on the stretch by the sagging organ, it is all that can be accomplished by such means, and the mere antever- sion is of no consequence. Any instrument making direct pressure on the anterior wall, the chief seat of disease and the point of greatest tenderness, must prove a source of irritation. I deprecate even more the intra-uterine stem-pessary, for, had this instrument been the device of the Evil One himself, its use could not be productive of more danger. Its use in a flexure seems as rational as would be the introduction of a straight