COMPLIMENTS OF THE AUTHOR. Traumatisms of the Urinary Tract BY JOHN B. MURPHY, A. M., M. D., of Chicago. Professor of Surgery and Clinical Surgery, College of Physicians and Surgeons, Chicago; Professor of Surgery, Post-graduate Medical School and Hospital; Attending Surgeon to Cook County Hospital; Attending Surgeon to Alexian Brothers' Hospital; President National Association reprinte! from I THE SURGEON m CHICAGO. COMPLIMENTS OP THE AUTHOR. Traumatisms of the Urinary Tract JOHN B. MURPHY, A. M., M. D., of Chicago. Professor of Surgery and Clinical Surgery, College of Physicians and Surgeons, Chicago; Professor of Surgery, Post-graduate Medical School and Hospital; Attending Surgeon to Cook County Hospital; Attending Surgeon to Alexian Brothers' Hospital; President National Association Railway Surgeons, etc. < REPRINTED FROM THE RAILWAY SURGEON Monadnock Block, CHICAGO. TRAUMATISMS OF THE URINARY TRACT. By John B. Murphy, A. M.,M. D., of Chicago. Professor of Surgery and Clinical Surgery, College of Physicians and Surgeons, Chicago: Professor of Surgery, Post-graduate Medical School and Hospital: Attending Surgeon to Cook County Hospital; Attending Surgeon to Alexian Brothers’ Hospital; President Na- tional Association Railway Surgeons, etc. The first systematic treatment of trauma- tisms of. the kidney was given by Rayer in 1840. The subject was not advanced by the writers of the next thirty years. The great Simon took it up in 1876 and advanced it to a higher stage than that of a collateral sub- ject. He was followed by Maas in 1878. From the time of the writings of the last two authors the subject has received careful con- sideration at the hands of many writers. Ex- periments and close clinical observations have given results upon which scientific treatment may be based. The most striking work that has appeared in this period is that of Edler, (Traumatische Verletzungen der Parenchy- matoesen-Unterleibs Organe: Archiv fur Klin. Chirurgie, B. 34, 1882). This work con- tains a large number of valuable statistics, although there is little advancement made in 4 the symtomatology and pathology of the authors first mentioned. Other able works are those of Grawitz and Schlange. Injuries of the kidneys may be classified as: First, contusions, those without laceration of the external tissues. Second, penetrat- ing wounds, involving laceration of the tissues as well as of the kidney. Third, ruptures into the peritoneal cavity, whether from pene- trating wounds or contusions. CONTUSIONS OF THE KIDNEY, WITHOUT EXTER- NAL WOUNDS. In considering this group we must be mind- ful of the fact that these injuries vary greatly in degree. The simple contusions, in which there is a slight hematuria, without tumefac- tion or phlegmon in the region of the kidney are of common occurrence, and require but little immediate attention from the sur- geon. Rest in bed for three or four days, abstention from work or violent exercise for ten or twelve days longer is all that is neces- sary in the treatment of sucli cases; though they should be carefully watched for second- ary lesion. The more serious cases of contusions (that is, contusions accompanied by severe hemor- rhage, both within and around the kidney, with tumerfaction and phlegmon) are not of rare occurrence, and tax the surgeon’s 5 judgment and skill to conduct them to a suc- cessful termination. Of this class Edler col- lected ninety cases, to which Grawitz added eighteen, making a total of 108 cases collected up to January, 1889. Since that time I find in the literature a rapidly increasing number of cases. Examples of this class of cases are the fol- lowing: Case I. R. D., aged 11 years, came under my observation the 10th of May, 1885. He was returning from school and was run over by a horse car, one wheel passing directly over his abdomen. Patient was taken home in a collapsed condition and remained so for several hours; he was paralyzed in the right lower extremity, and was unable to urinate. An examination was made and it was found that he was very tender in the area over the left kidney, and that the spinous process of the first lumbar vertebra was fractured; also the nth and 12th ribs on the left side. There was very slight external evidence of an injury to the abdomen. Restoratives were administered, and eight hours after the injury the patient micturated, the urine containing a large quantity of blood. The following day the tenderness in the region of the left kidney increased. There was a sense of fullness and pressure there, as ex- pressed by the patient. The blood continued in large proportions in the urine. This condi- tion remained unchanged until the fifth day, when the tumor became quite marked, and the patient developed a temperature of 101 (prob- ably the absorption fever of Bergmann and Angerer). The fever continued to increase, until at the end of three weeks it had reached in the evening. The patient was emaciat- ing rapidly. The tumor now filled up a greater portion of the left side and extended as far as the umbilicus. The blood had dis- appeared from the urine. It still contained some albumen and debris. A Lumbar incision was made, and about a quart of bloody pus and urine evacuated. An opening about an inch long was found extending from the pelvis of the kidney upward and outward. Urine flowed from the fistula for seven months. The paralysis of the limb (produced, undoubtedly, by the fractured spinous process) entirely dis- appeared, and the patient made an excellent recovery, having no evil effects from the in- jury. Cases II and 111 occurred in the prac- tice of my colleague, Dr. E. W. Lee. Case 11. C. J., aged 10 years, run over by a street car. He was caught under the car in such a manner as to “double him up.” Dr. Lee found him in a condition of extreme col- lapse and reaction was not fully established for nearly 36 hours. The urine was bloody. 7 An area of dullness could be outlined on the fourth or fifth day on the right side over the kidney; it was quite extensive. There was general abdominal tenderness. The case pro- gressed without any marked symptoms for about three weeks, when a well-defined tumor could be outlined. A temperature developed, showing absorption. A lumbar incision was made, evacuating a quantity of pus and urine. It took about four months for the fistula to close. Case 111. Wm. L., aged 24 years, while crossing a railroad track October 28, 1882, fell forward, the right hypochondrium coming in contact with the rail. He felt faint and sick immediately, and was removed to his home. Dr. Lee found him somewhat collapsed, pulse rapid and weak, and the urine bloody. Next morning a distinct area of dullness could be outlined over the right kidney in front; temper- ature normal; pulse slower, and fuller. The urine was occasionally bloody for the next week. He developed an evening temperature of 102 degrees, and November 13 had a chill, followed by a temperature of 103 degrees. November 14 a lumbar incision was made; evacuated about a pint of pus and bloody de- bris. Urine drained through the opening, which closed on December 17. Case IV occurred in my service at the 8 Alexian Brothers’ Hospital, in July, 1892. Frank F—, aged 22 years. He was thrown against the. edge of a coal bin in a rail- road accident. Immediately following the in- jury he was severely shocked, although he did not lose consciousness. When brought to the hospital he was suffering from severe pain in the abdomen; tenderness of the right kidney; no laceration of the external parts; urine con- tained a considerable quantity of blood. On the third day a distinct tumor could be felt at the position of the right kidney. There was no infiltration of the tissue, and no phlegmon. The patient’s temperature did not exceed These symptoms continued for about ten days, and then began to subside; the tumor dimin- ished in size; the blood gradually disappeared from the urine; and at the end of five weeks the patient left the hospital with a slight en- largement of the right kidney; .urine normal. These suffice as examples of injuries of this class. We will now take up their cause, and the method of their production. The most frequent causes of injuries to the kidneys are blows or kicks (particularly from horses), and falls in which the region of the kidney is brought in contact with a sharp point or edge. The kidney suffers more frequently when the force comes from the front or side, not so often when it comes from behind, ex- cept as in railroad injuries, where the entire 9 body is thrown with great force upon a flat surface; here the kidneys may be considerably lacerated. Indirectly, the kidney may be lacerated by suddenly doubling the body together, as il- lustrated in one of Dr. Lee’s cases. All of these injuries have but slight manifestations upon the surface of the body of their severity, because at this point the surface of the body is yield- ing and readily gives under force. Not infre- quently the ribs, or the spinous processes of the vertebrae are fractured, which shows the severity of the force. The anatomical condi- tion following injuries of this class is as fol- lows: Where the force is from in front we have the kidney protected by the intestine and the soft wall of the abdomen anteriorly; but posteriously we have the hard resistance of the rib, and to the inner side the spinal column. When the rib is fractured in conjunction with an injury to the kidney we may have the lat- ter punctured, as in the case of injuries of the pleura or lung, or we may have it lacerated in the line of the rib from pressure. The kid- ney is found torn in a more or less transverse or radiating direction from the hilus to the periphery, frequently dividing the kidney through and through, into an upper and lower portion; one of these may be entirely separated from its connection with the remaining por- tion of the kidney or pelvis. The following 10 explanation has been given as to the cause governing the direction of the laceration: The kidney is known to be made up in fetal life of from twelve to fifteen small bodies, the so-called “renculi,” which, in the first years of life, adhere and unite, leaving greater or lesser depressions at the line of union; and in many cases a deep fissure continues through life. There is also a depression in the capsule at the position of union of these bodies, and the blood vessels and connective tissue loop and separate to a considerable extent along, these lines; that is, their communication and interlacing is less at this point than any other portion of the parenchyma. This creates a congeni- tal locus minoris resistentise, and accounts for the direction of the line of laceration. The tendency to lacerations in this direction Gra- witz could not establish by experimental con- tusions in the dead subject. Still, he believed this was due to the absence of turgor in the cadaver. Aside from the lacerations we fre- quently have contusions of the parenchyma, accompanied by bloody and urinary infiltra- tion of the tissue. Extensive parenchyma- tous hemorrhages accompany almost every contusion of the kidney. Severe hemorrhages do not take place except where the larger branches at the pelvis are punctured. The injuries to the cortex rarely bleed severely, but transverse lacerations of the hilus close to the 11 attachment of the ureter, not infrequently rup- ture large blood vessels that run parallel to the long axis of the kidney, from which ex- tensive hemorrhage takes place. It is not un- common to have a vessel of one-eighth of an inch in diameter running parallel to the longer axis of the kidney. This I have frequently observed on the injected cadaver and in my experiments on dogs, and the surgeon should always be guarded against incisions in this po- sition. Another condition that favors severe hem- orrhage from laceration of the kidney is the large renal artery, and the high pressure that must exist in its branches. In order to have a urinary infiltration of the parenchyma of the kidney, it is necessary that the pelvis be lacerated When the pelvis and capsule are not lacerated a large blood accumulation may form in the parenchyma of the kidney, and but little appear in the urine, and none escape into the surrounding cellular tissue. But when the capsule is lacerated the blood will pour into the retro-peritoneal cellular tissue, and form a large tumor that may extend from the diaphragm to the pelvis. It is not uncom- mon to have both the capsule and pelvis lacer- ated. In these cases the blood finds a natural outlet through the ureter, and though a con- siderable tumor may form shortly after the in- jury, with a free communication with the cel- lular tissue, it is not uncommon to have this entirely disappear by drainage through the ureter. In rupture of the ureter in connection with laceration of the kidney no such drainage takes place, and the tumor remains and in- creases rapidly in size; finally a phlegmon is formed, involving a greater portion of the side. The condition is entirely changed when the peritoneum is lacerated as well as the kid- ney. Here you have a most dangerous com- plication. This occurs most frequently in children, as the peritoneum is more friable and its tension is greater in early life. The pronounced symptom immediately after injury is shock, and this shock has no specific characteristics to indicate a lesion of the kid- ney. It is the shock of severe abdominal in- jury, and would be present in impalement, con- tusion or laceration of any of the viscera of the abdominal cavity. It is not prolonged, however, beyond a few hours, except when accompanied by severe internal hemorrhage. Almost immediately after the injury, and be- fore the symptoms of shock have subsided, the patient complains of severe pain in the neigh- borhood of the injured kidney. This pain is increased very much on pressure or manipu- lation. The physical signs produced by the hemorrhage will depend: first, on the quantity; SYMPTOMS. and second, whether it is retained in the cellu- lar tissue or admitted into the peritoneal cav- ity. If it be retained in the capsule or cellu- FIG. I. DIAGRAMMATIC SKETCH SHOWING RELATION OF PERITONEUM TO KIDNEY, URETER AND BLADDER, AND DISTANCE BETWEEN PERITONEAL CAVITY, AND SYM- PPIYSIS PUBIS WITH BLADDER DISTENDED. tent depending upon the quantity of blood. When the peritoneum is lacerated the blood lar tissue, palpation and percussion will elicit the signs of tumor around the kidney, the ex- 14 escapes into the /peritoneal cavity, and the evidences of tumor are absent both in the neighborhood of the kidney, and in the great majority of cases in the peritoneum, unless the quantity of blood is very large, in the latter case you will have the symptoms of acute anemia. When the peritoneum is ruptured the manifestations of collapse are also more profound and of longer duration. (See Fig. I). An almost invariable symptom, and one of great importance, is that of hematuria. It is often excessive, but in rare cases it is entirety absent. The quantity of blood in the urine bears some relation to the extent and position of the laceration; and when it is great the prob- ability is that one of the large vessels of the pelvis is involved. Hematuria without tumefaction indicates that the capsule is not lacerated. The urine may be simply colored with blood, or it may be almost pure blood and coagulate when voided. Intermittent hematuria after a laceration of the kidney is not uncommon. The intermission is produced usually by a co- agulum forming in the ureter. During the intermission there is severe pain in the renal plexus, which may extend down into the tes- ticle, as in renal colic of calculus. Three or four days after the laceration the tissues at the side commence to show urinary infiltration. If the urine be aseptic it does not produce sup- 15 puration, but an infiltration of the tissues, ac- companied by excessive exudation in the cel- lular tissue, muscles and lymph spaces. This infiltration increases the density of the tissue, so that it often has a ligneous feeling, which prevents the detection of fluids by fluctuation, notwithstanding there may be a large quantity present. Percussion enables us to determine the outline and extent of the infiltration and accumulation. Gradually the tumor increases in size; its outlines become more marked, and after a week or ten days, or possibly two weeks, the patient commences to have a tem- perature that exceeds 100, fibrin intoxica- tion or resorption fever. From the quantity and character of the blood, except where it is very minute, it is impossible to say whether it comes from the kidney or bladder. Occasionally we have an angle- worm clot, or a bloody cast of the ureter. When present it is pathogomonic of renal hemorrhage. We have besides these symp- toms, those of vesical tenesmus or bladder colic. This was noticed most frequently by Simon, and is due to a coagulum forming in the neck of the bladder, preventing the- escape of urine. The renal and bladder colics both subside as soon as the clots break down and the free pas- sage is re-established. The hematuria lasts from one week to three; rarely longer. The above is the train of symptoms commonly present, except in the complicated cases; that is, where you have along with the laceration of the kidney a rupture of the intestines, stomach, gall-tracts, etc. The symptoms will vary in accordance with the particular organ injured, and would have in addition symptoms peculiar to that organ. One of the most diffi- cult complications, and indeed, one in which it is impossible to make a diagnosis without exploratory incision, is the laceration of the spleen, as is shown in the folowing case. J. P—, admitted to Cook County Hospital in May, 1879. Patient was in a buggy at- tached to a run-away horse, and was thrown from the vehicle and doubled up around a lamp-post, the force being centered below the margin of the ribs, and a little to the right side. When admitted to the hospital two hours later he was very much collapsed; in a cold, clammy perspiration, and complained of great pain in the abdomen; pulse feeble and frequent; lips pale and exsanguinated. The urine contained a large quantity of blood. Percussion showed dullness on the right side, and there was a frac- ture of the eleventh and twelfth ribs. The patient continued to fail, and died four hours after admission. Post-mortem: Peritoneal cavity full of blood. The spleen was macerated to a pulp. The left kidney was torn transversely in many places, and hung by shreds to the pelvis. The peri- 17 toneum over the kidney was also torn. The ribs did not penetrate the kidney. There was no injury to the intestines nor other internal organs. Cause of death, hemorrhage and shock. Fractures of the spine, rupture of the diaphragm, and rupture of the bladder occa- sionally accompany lacerations of the kidney. Prognosis: Of the 108 cases reported by Edler, 58 terminated in recovery. PATHOLOGY. We have in the nephritis traumatica primary healing and secondary healing. Primary healing takes place in the greater percentage of the cases; that is, the repair without a local- ized abscess or external opening. Of the 58 cases above reported as recoveries, 46 were of this class, and the average time was about three weeks. With secondary infection we have suppuration and a large abscess; or a large accumulation of blood, which requires considerable time for absorption and cicatri- zation. In these cases it is not exceptional to have bloody urine for weeks during the pro- cess of repair. Cicatrization takes place first outside of the kidney, and gradually approxi- mates the kidney substances itself. A loose connective tissue is developed at the point of laceration, Tuffier and Paoli believed that they observed in their experiments the repro- 18 duction of glomeruli in the cicatricial mass; but Barth in his more elaborate and extensive experiments and observations has come to the conclusion that the glomeruli are not re- produced. Maas is of the same opinion, and has found that after primary healing the scar continues to contract until a deep fissue is pro- duced at the position of the wound. If the lacerations have been extensive, when the pro- cess of repair is complete and the contraction has taken place, a great portion of the secret- ing surface may be destroyed; but this is rap- idly compensated for by the hypertrophy in the healthy tissue. In the complicated cases of rupture of the kidney, or the cases of secondary union with suppuration, the mor- tality is greater. Grawitz found in 17 cases of secondary union 10 recoveries. The cause of the suppuration has not been satisfactorily explained. Healthy urine does not produce suppuration, as has been shown many times by experiments, and as I have also demonstrated experimentally; but it does pre- pare the tissues for suppuration, necrosis and gangrene, that is, tissues infiltrated with urine if they become infected, rapidly break down and slough. This should be kept in view in treating all traumatisms involving the urinary tract. We have before the injury presumably a healthy condition of the bladder and kidneys. We should be careful to perform no operation 19 nor procedure that would be liable to infect the tissues; for if infected the suppuration would be great. It was for a time believed that alka- line urine would produce suppuration; but that is not true, unless the alkalinity is produced by (decomposition. Urine will produce an in- flammation, or an excessive regenerative re- action, or cell proliferation; but without the admission of microphytes from without there will be no suppuration. Experiments have shown that lacerations and incisions of the kidney, where there is no loss in substance, re- pair themselves in from ten to twelve days. Where infection takes place the healing is very much retarded, and if the circulation is defec- tive in portions, it is likely to become necro- tic, as in the case recently reported in the New York Medical Record. The modus operand! of infection of the kidney is first and most frequently along the urinary tract, and second through the blood; third through the intestinal canal. First Source.—The most frequent source of infection is through the urinary tract from below, as from gonorrhea, cystitis, or more frequently in connection with injuries to the kidney, faulty catheteriza- tion. The latter procedure is so fre- quently 'performed in a careless; indeed, I might say, dirty manner, that many of the -cases receive their infection from this source. Second Source.—The kidney is recognized as an eliminator of many kinds of bacteria; it is also recognized as the position in which emboli in pyemia, erysipelas, pneumonia, scar- let fever and diphtheria are most frequently arrested, and produce suppurating foci; and as in injuries of the kidney, we have a locus minoris resistentise it would therefore be ex- pected that the microphytes would here be ar- rested, and that they would find a favorable nutrient material for their development. The experiments of Rhine on the lower animals, however, do not justify this theory. 20 Third Source.—The third channel for infec- tion is through the injury of a portion of the intestinal tract in close proximity to the lacer- ated kidney. It is not necessary that there should be a perforation of the bowel, but a traumatic ulcer of the bowel may infect the lymphatics, and by its contiguity to the in- jured kidney produce a suppuration of the latter. CAUSES OF DEATH. Of the 108 cases quoted above 50 terminated fatally—46.3 per cent. Of the 50, 18 were complicated, giving us a mortality in 90 un- complicated cases of 35.5 per cent. It is my belief that this mortality is too high, as many of the milder cases were not reported. The causes of death may be divided into: First, shock; or better, shock accompanied by hem- 21 orrhage. Fourteen of the 108 cases died from this cause on an average of from fifteen to twenty hours after the injury. The quantity of blood found in the abdomen was very much less than would have been necessary to pro- duce death from injuries to the extremities or blood vessels without the element of shock. We know that death from hemorrhage is due not alone to the quantity of blood lost, but that the rapidity with which the blood pressure is lowered is an important cause of sudden death from hemorrhage. When the perito- neum is opened the shock is greater. Not- withstanding that the urine does not produce suppuration, it does produce peripheral nerve irritation, and in that way adds greatly to the element of shock. Second, continuous hem- orrhage for a long time produced death in eight cases. Third, suppuration of the kidney or peri-renal tissue, produced death in seven cases. Fourth, from uremia three deaths. TREATMENT. The treatment of injuries of the kidneys should be such as would overcome the causes of death in such accident. We find in the analysis of the causes of death primary hem- orrhage and shock in 15.5 per cent of the cases. The first indication, therefore, to be met is the hamastasis; can we, by external pressure, by position, by manipulation, in any way lessen the hemorrhage? No. Where we have the symptoms of exsanguination following trau- matism, with bloody urine and local tender- ness, there is but one means of suppressing that hemorrhage, and that is by operation, effecting compression or ligation of the renal vessels, or extirpation of the kidney. Is such an operation justifiable? In cases of laceration of the kidney with severe symptoms it certainly is. Not only can we extend some hope to the 15 per cent who die fromprimary hemorrhageand shock,butwe can also lessen the danger from the 9 per cent that die from secondary hemorrhage, making a total of 24 per cent of the cases whose chances would be increased by an immediate operation. In addition to this we can certainly lessen the mortality of the 16 per cent that die from com- plications, such as rupture of the gall-bladder, intestines, stomach, etc., by immediate action. The indication, therefore, in lacerations of the kidney with severe symptoms is immediate exposure of the kidney: (a) by laparotomy; (b) by lumbar incision; the former is always to be given the preference. In modern surgery is there any other field where hemorrhage (primary and secondary), or lacerations of the viscera are allowed to continue with a mortality of 24 per cent with- out the surgeon making an effort to reduce it? It is my firm conviction that we are swerv- 23 ing in our our patient when we stand idly by and allow a condition that neces- sitates a mortality of 46.40 per cent to continue without making an effort to save the life of the patient. The indication in the milder cases is the opposite. We should wait. If a suppuration or a large accumulation forms, it can readily be drained; this should always be done by the lumbar incision; and indeed, a portion of (or even the entire) kidney may be removed, two, three or more weeks after the injury, if it be in- dicated. The septic symptoms are usually very mild, showing but a low degree of intoxica- tion, making but slight inroads upon the strength of the patient, and allowing the sur- geon ample time to consider all the bearings of the case before he is compelled to operate. When drainage is established the opening should be large and kept patulous. It is pre- ferable in these cases not to operate until the third or fourth week, as the injured tissues have by this time regenerated, and are in bet- ter condition to withstand the secondary in- fection, which frequently takes place after the operation, than they would be at an earlier time. Where the ureter is permeable the fis- tula will finally close, though it may continue to discharge for months. The cases of traumatic nephritis in which the symptoms of uremia occur must be treated from a medical standpoint, with water, diure- tics and proper diet. Penetrating wounds are rare accidents in railway surgery, and for that reason will not be considered in extenso here. I would merely say that the symptoms and indications are practically the same as for those of the sub- cutaneous variety, the greatest precaution be- ing taken to keep the wound aseptic, and if the peritoneum be invaded as a complication, suture it immediately and shut it off from the renal lesion and drain in front. Injuries of this class are produced more frequently by railroad accidents than any other form of traumatism of the urinary tract. We will divide them into three classes. First, ruptures into the peritoneal cavity. Second, sub-peritoneal ruptures. Third, ruptures of the neck into the pelvic cellular tissue above the triangular ligament. TRAUMATIC RUPTURES OF THE BLADDER. All of these may, or may not, be accompa- nied by external openings. More frequently they are not. Ruptures of the bladder have been recognized, treated and feared for cen- turies. Heinrich von Ruhnheisen wrote the first classical description of this class of in juries in 1663. The ruptures may be produced by severe blows in the pelvic region; by the body being 25 thrown with great force against solid objects; by crushing injuries, as between bumpers, by being run over with heavy weights or wagons; they are frequently accompanied by fractures of the pelvis, the fragments of bone producing the laceration. Bartels, in 1878, found in 504 injuries to the bladder 169 ruptures. Rivington, in 1882, re- ports 322 cases of bladder rupture, of these 183 were intra-peritoneal, and 119 extra-peritoneal. Of the 183 intra-peritoneal only one recovered. Of the 119 extra- peritoneal twenty-six recovered. A suc- cessful case of intra-peritoneal rupture oc- curred in the practice of Dr. Walter of Pitts- burg, where he performed an immediate lapa- rotomy and suture of the bladder. To Walter, therefore, belongs the honor of being the first to outline a rational treatment for ruptures of the bladder. The procedure previous to that, (and indeed, by many since) has been the per- manent catheter. From the time of Simon it has been established that healthy urine in the peritoneal cavity does not produce septic per- itonitis. Why, then, should the mortality be so great? While urine in the peritoneum does not pro- duce suppuration, it does produce an abrasion, that is, an exfoliation on the endothelium ot the peritoneum, and thus prepares the surface for infection and rapid absorption. Schlange, in 1892, collected 33 cases operated; 22 for intra-peritoneal rupture, with 10 recoveries and 12 deaths; 10 for extra-peritoneal rup- ture, with seven recoveries and three deaths. At first sight this would seem to be a great advance; but I doubt if the statistic justify the conclusion that 40 per cent of these cases have been saved, as many unfavorable ones are not reported. Still, it does justify beyond question laparotomy for intra-peritoneal laceration. Let us take some examples. In September, 1890, I saw with Dr. J. W. O’Connor, chief surgeon of the Denver & Rio Grande, a case at his Salida hospital. The patient had been injured in a wreck two days before. He was suffering from a fracture in the pelvis; had great pain in the abdomen; tender; tympanitic, and in no place could a distinct outline of dullness be determined. His pulse at the time we saw him was about 140; his temperature 101. Several hours after the injury he was catheterized and a small quan- tity of bloody urine obtained. A few hours later the catheter was again passed, and only a few drops of blood. The next morning catheterization was repeated, and by pushing the instrument in as far as possible, a large quantity of bloody urine (something like a quart) flowed out. Subsequently the catheter gave but a little clear urine. At the time we saw him his expression was bad; he was col- lapsed, and his condition such that he would not tolerate any operative interference. Diagnosis: Rupture of the bladder. Post- mortem the following day. The abdominal wall slightly infiltrated with serous exudate. Peri- toneum excoriated, inflamed, and the pelvis contained a considerable quantity of sero- purulent urine and blood. Bladder contracted. There was an extensive laceration of the blad- der on the posterior surface, extending through the peritoneum. A multiple fracture of the pelvis. Cause of death, peritonitis from rup- ture of the bladder. It is evident from the post-mortem that the small quantity of bloody urine, and the clear urine withdrawn with the catheter, were taken from the bladder. The large quantity withdrawn on the second morn- ing was taken from the peritoneal cavity by the passage of the catheter through the open- ing in the bladder into the peritoneal cavity. Dr. Fernand Henrotin kindly furnished me with the history of the following case; Male., aged 15 years. Admitted to the hos- pital April 6, 1895. A few hours before, while leaning over a banister, he lost his balance: fell three stories, landing on his hip and right side. Collapsed after the injury, but was not unconscious. No bones broken. Com- plained of very severe pain in the abdomen, the latter was tense and tympanitic. In- ability to produce bowel movement. Fre- 28 quent vomiting and constant nausea. No urine was passed in the first twenty-four hours. A little blood was discharged after efforts at urination. No hemorrhage from the urethra. After catheterization a small quantity of clear urine was obtained. .Laparotomy; large quantity of blood and urine in peritoneal cavity; laceration of bladder not found, as patient’s condition was too extreme to per- mit prolonged search; abdominal drain; urine discharged through incision for three days and patient succumbed. Post-mortem not per- mitted. In arriving at a definite diagnosis in lacera- tion of the bladder the history of the case must be taken into consideration, and a careful ex- amination made of the boney framework of the pelvis. In the absence of fracture of the pelvis, with the remaining symptoms of rup- ture of the bladder, the chances are that the rupture is of intra-peritoneal variety, and not a rupture into the cellular tissue of the pelvis. On the other hand, when it is accompanied by a fracture of the pelvis, the bladder is very likely to be lacerated at the neck, and extra- peritoneally, careful palpation and percussion should be made of the abdomen and pelvis. The area of dullness may be found either lo- cated centrally or to one side. Palpation through the rectum and vagina may assist us DIAGNOSIS. 29 in outlining the tumor. If the resistance to the wall of the abdomen be too great, it will be necessary to place the patient under an anaes- thetic, and to prepare for a laparotomy. The diagnosis must be made at the first examina- tion; that is, we are not justified in allowing the patient to go for hours and hours with an indefinite idea of the condition. It will be noted so far that I have refrained from mentioning the catheter. The catheter should not be used as an aid to diagnosis if the patient is able to urinate, but if he is not able to urinate it must be passed, and all the aseptic precautions taken in inserting the cath- eter that would be taken by a man with an aseptic conscience if he intended to insert that catheter into the peritoneal cavity; for if the patient has a rupture of the bladder it is pos- sible that the catheter will be passed directly into the peritoneal cavity, and even though it be not passed through the peritoneum and the rupture exists the catheter will set up a decomposition of the urine and blood in the bladder, and this will rapidly spread through the opening into the peritoneal cavity. It is my belief (and it is based on the observa- tions of a long hospital service), that there are more lives sacrificed and more subsequent trouble and pain produced by uncleanly cathe- terization than by any other operative proce- dure indulged in by physicians to-day. True, the majority of physicians to-day do not spit ron the catheter for the purpose of lubricating it; but many do slip their hands into their pockets, draw out the catheter, and insert it without disinfecting the catheter, their hands or the genitals. In this connection I do not allude to the permanent catheter. That will be considered under the subject of treatment. The information that we can derive from catheterization, is the quantity and character of the contents of the bladder. If it be small and bloody and the patient has not urinated for a considerable time previous to the injury, it signifies rupture. We must be careful to note that the eye of the catheter is not closed with a blood clot, as a very distended bladder under such circumstances could not be evac- uated. If no urine is withdrawn from the bladder it may be filled with a colored salt so- lution by means of a siphon attached to the catheter, the quantity being first measured ex- actly, using on the average a quart of water. This should then be made to siphon off and again measured. If there be a noticeable dif- ference in the quantity, and the catheter is not closed by a blood clot, the chances are alto- gether in favor of a rupture of the bladder. The increase in the area of dullness in the ab- domen should be noted before filling, while full and after emptying the bladder. When this procedure is undertaken every prepara- tion must have been made to do an imme- diate laparotomy. 31 Now if the fluid does not return, and we are convinced that it is a rupture of the bladder, the question arises; is it intra-peritoneal, sub- peritoneal, or intercellular? If of the intra- peritoneal variety, the fluid passes in with less force, and the dullness will become more dif- fuse. In the sub-peritoneal variety, as shown by the following history, the tumor will be circumscribed, and will be highest in the cen- ter. DR. ALEX. C. WIENER’S CASE. F. D—, a healthy, strong man, aged 28 years. While unloading railroad iron fell back- ward, with a rail crossing his abdomen. Be- came unconscious immediately, but soon re- acted, was taken to his home, and went to bed. Was unable to urinate; had severe vesical tenesmus. In the evening he became tym- panitic and complained of great pain in the abdomen. The following morning the patient collapsed; pulse 130; temperature sub-normal. Abdomen very tympanitic; dullness over lower portion of abdomen, having the outline of a very much distended bladder, or an ovarian tumor. Catheterization produced only a few drops of bloody urine. Diagnosis: Extra-peritoneal rupture of the bladder; sectio alta. Removed to the Stadt- krankenhaus. As soon as the deep fascia and 32 the pre-vesical space was opened there was a gush of bloody urine, as if under considerable pressure. Deep down in the sub-peritoneal space was found a contracted bladder, in the apex of which was an opening three quarters of an inch in diameter. The peritoneum was pushed up into the abdomen, and a large quan- tity of fluid had accumulated in a sac, sur- rounded by peritoneum above. As the fluid escaped the peritoneum fell back in the direc- tion of the bladder. The opening in the blad- der was sewed with silk, and a drainage tube inserted in the sub-peritoneal cavity between the bladder and the peritoneum. This was re- moved on the third day. There was no frac- ture of the pelvis. The patient made an un- eventful recovery, and was discharged from the hospital in four weeks. This case illustrates beautifully the method in which the peritoneum is separated from the bladder, and the large quantity of urine that may be accommodated, without rupture into the peritoneal cavity. It also illustrates the indication for treatment in those cases where there is laceration; that of immediate suture of the bladder and thorough drainage be- tween it and the peritoneal cavity. In this class of cases it can be readily seen why the peritoneum is pushed in advance of the urine, and forms a second urinary sac (extra-peritoneal), between the peritoneum and the wall of the contracted bladder. It can also be seen that an exploration of the bladder from the perineum, and through the perineal sec- tion with the finger is not possible, particu- larly if the patient be at all obese, and even if you find a laceration in the bladder you can- not (determine whether 'the laceration con- tinues through the peritoneal coat, or whether the peritoneum be pushed forward ahead of the fluid and separated from the other coats of the bladder. The proper operation for such cases, both with a positive diagnosis of intra-peritoneal rupture, or with a doubtful diagnosis of intra-peritoneal rupture, or with a diagnosis of rupture into the cellular tissue, is a supra-pubic section. The bladder can be opened through this incision and explored without opening the peritoneal cavity, and if the urine be sub-peritoneal, it can be drained through this opening. If the opening in the bladder be sub-peritoneal it can be sewed through this incision. If the rupture is intra- peritoneal, the peritoneum can be opened by increasing the incision an inch upward, and the cavity can be irrigated and drained through the same opening. A permanent drainage of the bladder can also be made through the lat- ter, thus placing it in a most favorable condi- tion to keep the escaping urine aseptic. With a glass speculum the surface of the bladder can be thoroughly examined with the eye as well as digitally. The ureter can be examined and re-united if ruptured, and hemorrhage can be suppressed, all through the same incision. In other words, every indication (immediate and remote) in connection with intra-perito- neal rupture of the bladder can be made by this method of operating, and that without jeopardizing the patient by the operation itself, or the function of the neck of the bladder dur- ing subsequent years. It was first suggested by Gutesbock, and performed by Mikulicz After the bladder is open a careful examina- tion of the surface should be made, not alone for one opening, but for many, as the rupture is frequently multiple. The usual incision for supra-pubic section should be made. The tissues will be found infiltrated with blood and urine; the bladder will be found deep in the pelvis and contracted. It cannot be elevated with a rectal bag in these cases. When the bladder is opened and the anchor stitches are placed in position a digital exploration may be made, and then an examination with a speculum. If it is found that the bladder is ruptured into the peritoneal cavity, the in- cision should be enlarged upward, and the peri- toneal cavity opened. The bladder closed with a Czerny-Lembert suture. The peritoneum should then be thoroughly 'cleansed, thor- oughly irrigated with a salt solution, the ureters examined, and a large glass drain in- 35 serted. The bladder should be sutured to the abdominal wall, and a speculum or a drain an inch in diameter retained in the opening in the bladder. It can in this way be frequently irrigated. What are the dangers? First, there is dan- ger of peritonitis from the effect produced to the peritoneum by the urine. In these cases death occurs as a rule from the third to the fifth day. Second, there is danger of absorp- tion of the infiltrated urine in the pelvic cellu- lar tissue. Third, there is danger from necro- sis of the cellular tissue, and extensive slough- ing produced by the decomposed urine. The indications, therefore, are: prevent fur- ther contact of the urine with the peritoneum, and provide thorough external drainage for the urine from the bladder. This cannot be done with a small drainage tube, nor with a siphon, but must be done with a glass specu- lum an inch in diameter. Where the perito- neum is separated from the bladder wall and the wall of the abdomen, and the urine rests in the sub-peritoneal space, great care should be taken not to open the peritoneal cavity, but to drain by a supra-pubic incision, as in the case kindly furnished me by Dr. Alex. C. Wiener. Wherever there has been a urinary infiltra- tion in any tissue, the most careful provision must be made for drainage, as it rapidly de- 36 composes when exposed; and when decom- posed its destructive effect is very great. The most common ruptures of the bladder are those of the neck; and they are usually associated with fracture of the pelvis. The symptoms are very similar to those above- mentioned, except that the area of dullness does not extend up in the direction of the peritoneal cavity; but there is infiltration, ten- derness, tumor in the supra-pubic space (or evidences of tumor), and an infiltration to be felt in the pelvic cellular tissue through the vagina or rectum. Where we are able to ex- pose the laceration in the bladder, and through that to explore the bladder for other lacera- tions, it is not necessary to make an incision into the bladder. But where we are unable to locate the opening in the bladder, it should be opened supra-pubically, the location of the wound determined, and the same sutured. With immediate suture of the incision in the bladder we should resort to drainage of the space between the bladder and peritoneum for three or four days, until we determine whether or not primary union will take place. Itls un- necessary in these cases to keep the bladder in the external wound. It is also unnecessary to keep it open, as we can drain the line of suture and incision thoroughly after they are approx- imated; and in case of leakage it will not escape 37 into the cellular tissue and through the perito- neum, but along the line’ of free drainage. There should be free incision into the infil- trated area, and the most thorough antiseptic precautions taken. The tissues should be irri- gated and constantly saturated with a boric acid solution. LACERATIONS OF THE URETHRA BELOW THE TRIANGULAR LIGAMENT. These are by far the most common injuries to the urinary tract. A kick, a blow, a fall, striking on a hard body with the perineum very frequently lacerates the urethra, with or without a fracture of the pelvis. More fre- quently without. These lacerations may be divided into partial and complete, that is, first, in cases where the urethra is torn only for a portion of its circumference, where it is possi- ble for the patient voluntarily or with the aid of the catheter to evacuate the urine; and second, where there is complete laceration, and when the patient makes an effort to urinate he feels an intense burning and sense of pressure in the perineum. Method of production: The urethra is im- pinged between the foreign body and the sym- phesis and lacerated; the force of a sharp ob- ject pressing the urethra against the corpus cavernosum may produce the laceration; or the laceration may be produced by a fracture 38 of the pelvis, or by penetrations of the peri- neum. (See Fig. II.) Symptoms: Hemorrhage from the meatus; pain and burning in the perineum; inability to urinate, and when an effort is made, pain, burning and pressure are experienced in the perineum. In these cases it is not uncommon to have FIG. 2. ILLUSTRATING RELATIONS OF TRIANGULAR LIGA MENT (DEEP PERINEAL FASCIA) TO URETLIRA, ETC. (FROM GRAY). an infiltration of urine in the cellular tissue of the thigh, and along up the cellular tissue of the abdomen in the direction of the umbilicus. But if a case receives proper treatment at the start, that is, early operation and drainage, this does not take place. 39 Physical signs; Swelling and infiltration or the perineum; tenderness on pressure; inabil- ity to pass catheter; distended bladder. Pathology: When the urethra is lacerated partially, or completely, the patient is unable to urinate; or if he does, it is but little and very painful. The urine is forced out by the con- traction of the bladder, and through the lacera- tions into the cellular tissue of the perineum into the corpus spongiosum; and the quantity may be so great as to produce a distinct swell- ing of the perineum, the buttocks, or even pass up onto the side of the leg. Catheteri- zation, if attempted, is ineffectual in relieving the bladder. The urethra at the point of laceration is thereby infected, and we have* a rapid decomposition of the urine in the cellular tissue, and a further infiltration at each effort to urinate. The distress becomes so great that the patient must have relief. The indications are: First, to relieve the distended bladder. Second, to relieve the urine from its retention in the perineum. Third, to provide a permanent and free escape of the urine. Fourth, if the tissues are exten- sively infiltrated, to give free exit to the fluid producing the infiltration. Fifth, to re-unite the urethra. The distended bladder is relieved by (a) the passage of a soft rubber aseptic catheter, with the hands and genitals thoroughly disinfected. If this fails (and it should not be persisted in for too long a time), the next indication (b) is immediate perineal section for the relief of the distended bladder and infiltrated perineum, at the seat of the laceration. One of the great- est difficulties in this operation is finding the proximal end of the urethra, particularly after the case has existed for a number of days. The steel sound or silver catheter should be passed down into the opening of the urethra; a free incision should then be made and the end of the catheter and the tissues carefully inspected; and with a grooved director an en- deavor made to locate the proximal end of the urethra. The tissues may be found cut, torn, lacerated, in fact mutilated, without greatly jeopardizing the patient. The prosta- tic and membranous portion of the urethra may be proximately located by passing the finger into the rectum and following it down. The search for the urethra may be kept up for an hour. If success has not attended by that time, it is advisable to allow the patient to come from under the influence of the anaes- thetic, and have him endeavor to urinate. The urine will frequently flow out through the wound. You have then accomplished the first and second indications. With the uretha thus opened the urine may escape through the wound immediately on the patient’s efforts to ■urinate. The proximal end of the urethra 40 41 can then be readily located, and should be joined by suture, where it is possible, to the distal; and an opening retained for permanent drainage. If it be impossible for the patient to urinate after this procedure, and the urethra has not been found, his bladder may be aspirated with a fine needle in the supra-pubic position; or a supra-pubic cystotomy may be performed, though this is rarely necessary. When the urine escapes freely through the perineal wound in the efforts at urination, it is not necessary to keep in the catheter. Indeed, it is highly desirable that it should not be used at all. If it is impossible to bring the ends of the urethra together, a catheter should be inserted into the urethra and passing down to the sphincter, and retained there to aid in the for- mation of a permanent canal. On what class of cases of laceration of the urethra should we perform perineal section? On every case of traumatism to the perineum in which the urethra is involved; where there is hemorrhage from the meatus; a material diminution in the size of the stream; and where it is impossible for the patient to urinate and the catheter does not readily pass into the bladder. By this I mean, in every traumatism where the urethra is lacerated sufficiently to allow of infiltration of urine into the peri- urethral tissues. Yes, I will even go further, 42 and say in every traumatism to the perineum where there is hemorrhage from the meatus, and where the patient cannot urinate volun- tarily and freely. When should this operation be performed? At the time when the attending physician en- deavors to pass the catheter for the first time after the injury. There should be no attempt at catheterization unless everything is in readi- ness for an external urethrotomy. If the patient goes for hours without urinating after the injury, there is no material destruction in his perineum, as the urine is aseptic, and it in- filtrates the tissue slowly; but just as soon as the catheter is passed, just so soon is decom- position of the urine set up, and immediately the destructive effect of the decomposed urine on the tissues commences. The operation in the early stage is a very simple one, that is, within three or four, or even ten hours after the injury, as the tissues still retain their natural color; impart about a natural sensation to the touch; can be recog- nized by their appearance; and are still in their proper anatomical relations. Now this is all changed in twenty-four, thirty-six or forty- eight hours, particularly if the doctor has spent an hour or two trying to pass a metallic catheter through the urethra. In my opinion the metallic catheter in traumatisms of the urethra is a surgical abomination. Its only 43 potentiality over the elastic is its power to do damage. A soft catheter will pass if the urethra be permeable. A hard catheter can- not be forced into the bladder after it has es- caped from the normal tract of the urethra without making a false passage. It is merely forced into the perineum, into the peri-vesical cellular tissue through the triangular ligament; yes, it has been recorded many a time that it was forced into the peritoneal cavity. It should never be used for the purpose of cath- eterization in the presence of laceration. Its only use should be as a guide to the position of laceration. What are the evil consequences of such a procedure? First, the perineum is severely lacerated around the urethra. Second, the triangular ligament may be perforated, and the pelvic cellular tissue then become infil- trated. Third, the opening in the urethra is made larger; the tissues in the perineum are so torn that the urine freely infiltrates the peri- neum; and worse than all this, the laceration in the urethra is infected, and decomposition of the urine is set up. As a consequence of the infiltration and decomposition we may have the perineum, the scrotum, the corpus spongiosa entirely destroyed, so that the testicles become uncovered and even the tissues of the abdomen may become necro- tic. It has been my painful experience to see 44 three of these cases during the last two years. In all three the entire urethra, from the posi- tion of laceration to the meatus, was destroyed; the skin and cellular tissue of the penis de- stroyed, the testicles left without a particle of dartos to cover them; and though the patients succeeded in escaping with their lives, one of them lost both testicles, one lost one testicle, and in another the testicles were covered with a flap from the thigh; and in all three the pa- tients were compelled to urinate subsequently through a perineal fistula. These are three extreme cases, and true, are only met with in extensive hospital practice; but every surgeon, even with limited practice, has seen examples of lesser degrees of severity of perineal fistulse, destruction of two or three inches of urethra, sloughing of a portion of the scrotum, or peri- neum, two or three months of confinement to bed from infiltration, and not so wery infre- quently deaths from sapremia. We, as railroad surgeons, should consider ourselves as a body of organized men where each individual feels it his duty to cry down careless, meddlesome, pernicious, yes, even criminal catheterization after lacerations of the perineum. The pocket catheter must go, and its place in the perineum must be supplanted by the guide and scalpel. An incision into the urethra has little more danger than an incision of the 45 same size and depth into the calf of the leg. When I speak of incisions of the perineum into the urethra, I imply always incision into the urethra below the triangular ligament. We are never justified in passing beyond that land- mark in any effort to enter the bladder. Fur- thermore, we are never justified in performing the so-called Coxe’s operation, that is, putting the finger into the rectum, and stabbing for the apex of the prostate. In my interneship in the county hospital I saw two cases of this class. In both of them the triangular liga- ment was opened into the cellular tissue, and both patients died from pelvic urinary infiltra- tion and sapremia. When we are unable to get a guide into the bladder or find the urethra below the ligament, we have always left that simple and safe operation, supra-pubic section. Laceration and traumatism of the ureter occur most frequently with fractures of the pelvis or severe contusions of the abdomen, and are produced by penetration into the pelvic cellular tissues, or they may occur in abdominal operations. They may be: (a) extra-peritoneal (b) intra-peritoneal. If they are extra-perito- neal, the urine will accumulate beneath the peritoneum, and there will be a bulging cystic tumor at the position of laceration. This may be either above or below the pelvis. The urine immediately after the laceration may 46 have a small quantity of blood, or, if the ureter is still patulous, the blood may continue in the urine for some time after the accident. If the laceration is intra-peritoneal, we have all the symptoms of the escape of urine into the peritoneal cavity, inflammation, vomiting, shock, etc. It is not uncommon after the first bloody urine passes to have the urine remain clear throughout the course of the case. The indications are, if extra-peritoneal, that the operation should be performed extra- peritoneally. The operation on the ureter above the pelvis can readily be made in this manner by an elongation of the incision usually made for lumbar nephrectomy, one inch anterior to the ilium, and down to the middle of Poupart’s ligament. The peritoneum can then be pushed forward as in ligation of the iliac; and the ureter can then be ex- posed from the brim of the pelvis to the kid- ney. By this operation the danger of cellular infection is increased; but the danger of peri- tonitis, which is the graver, is avoided. When the ureter is exposed, if it be completely sev- ered, the method of ureterectomy originally suggested and performed by Dr. Weller Van Hook of this city, is the best method for re- uniting it. If the laceration be longitudinal, it can be sewed and united by extra-mucous sutures of 47 silk or catgut. If the laceration be trans- verse, and the ureter only partially divided, the method of elongation and lateral suture of Dr. Christian Fenger should be adopted.